locus-tag	class	description
CLI14_00005	COG0445	tRNA wobble uridine modification
CLI14_00015	COG1192	Involved in chromosome partitioning
CLI14_00020	COG1475	DNA binding
CLI14_00025	COG3312	ion transport
CLI14_00030	COG0356	it plays a direct role in the translocation of protons across the membrane
CLI14_00040	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CLI14_00045	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLI14_00050	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CLI14_00055	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CLI14_00060	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CLI14_00065	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CLI14_00075	COG2814	Major facilitator Superfamily
CLI14_00080	COG0583	DNA-binding transcription factor activity
CLI14_00085	COG0183	Belongs to the thiolase family
CLI14_00095	COG1739	Uncharacterized protein family UPF0029
CLI14_00100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CLI14_00105	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CLI14_00160	COG0352	thiamine-phosphate diphosphorylase activity
CLI14_00170	COG2104	thiamine diphosphate biosynthetic process
CLI14_00180	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CLI14_00185	COG0006	proline dipeptidase activity
CLI14_00185	COG0006	proline dipeptidase activity
CLI14_00210	COG1522	sequence-specific DNA binding
CLI14_00215	COG0742	ribosomal rna small subunit methyltransferase
CLI14_00225	COG0697	spore germination
CLI14_00230	COG0589	response to stress
CLI14_00235	COG1528	Iron-storage protein
CLI14_00250	COG2081	HI0933 family
CLI14_00260	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLI14_00265	COG1129	ABC transporter
CLI14_00270	COG1879	ABC-type sugar transport system periplasmic component
CLI14_00275	COG1069	ribulokinase activity
CLI14_00285	COG2160	L-arabinose isomerase activity
CLI14_00305	COG1322	Protein conserved in bacteria
CLI14_00320	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CLI14_00330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLI14_00335	COG0805	protein transport
CLI14_00345	COG0084	hydrolase, TatD family'
CLI14_00355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLI14_00355	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLI14_00360	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CLI14_00385	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLI14_00390	COG0583	DNA-binding transcription factor activity
CLI14_00400	COG2960	long-chain fatty acid transporting porin activity
CLI14_00405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLI14_00410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLI14_00415	COG1309	transcriptional regulator
CLI14_00470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLI14_00525	COG2433	Pfam Transposase IS66
CLI14_00545	COG3081	Nucleoid-associated protein
CLI14_00565	COG2433	Pfam Transposase IS66
CLI14_00575	COG5290	Psort location Cytoplasmic, score
CLI14_00620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLI14_00625	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CLI14_00630	COG0339	signal peptide processing
CLI14_00635	COG0210	DNA helicase
CLI14_00640	COG1280	lysine exporter protein (LysE YggA)
CLI14_00650	COG2962	Rard protein
CLI14_00655	COG0514	ATP-dependent DNA helicase (RecQ)
CLI14_00675	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CLI14_00680	COG1263	PTS System
CLI14_00680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLI14_00685	COG1132	(ABC) transporter
CLI14_00690	COG4774	siderophore transport
CLI14_00695	COG1120	ATPase activity
CLI14_00720	COG0612	Peptidase, M16
CLI14_00760	COG1061	Type III restriction enzyme res subunit
CLI14_00795	COG1396	sequence-specific DNA binding
CLI14_00810	COG1561	YicC-like family, N-terminal region
CLI14_00815	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CLI14_00825	COG1560	Kdo2-lipid A biosynthetic process
CLI14_00830	COG1560	Kdo2-lipid A biosynthetic process
CLI14_00835	COG1309	transcriptional regulator
CLI14_00840	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CLI14_00855	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CLI14_00865	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CLI14_00870	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CLI14_00875	COG0859	PFAM glycosyl transferase family 9
CLI14_00880	COG0463	Glycosyl transferase, family 2
CLI14_00885	COG0859	PFAM glycosyl transferase family 9
CLI14_00890	COG3642	lipopolysaccharide core region biosynthetic process
CLI14_00905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLI14_00915	COG1519	Transferase
CLI14_00930	COG0859	PFAM glycosyl transferase family 9
CLI14_00935	COG3307	-O-antigen
CLI14_00945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLI14_00970	COG1682	transport, permease protein
CLI14_01000	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CLI14_01025	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLI14_01035	COG0463	Glycosyl transferase, family 2
CLI14_01065	COG3754	Rhamnan synthesis protein F
CLI14_01090	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CLI14_01100	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLI14_01120	COG1596	polysaccharide export
CLI14_01125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLI14_01165	COG0438	transferase activity, transferring glycosyl groups
CLI14_01180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLI14_01185	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CLI14_01195	COG0668	transmembrane transport
CLI14_01200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLI14_01205	COG3068	Protein conserved in bacteria
CLI14_01210	COG2852	Protein conserved in bacteria
CLI14_01215	COG1253	flavin adenine dinucleotide binding
CLI14_01220	COG0776	regulation of translation
CLI14_01230	COG0151	Belongs to the GarS family
CLI14_01240	COG0789	Transcriptional regulator
CLI14_01250	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CLI14_01255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLI14_01260	COG2264	protein methyltransferase activity
CLI14_01265	COG0439	Biotin carboxylase
CLI14_01270	COG0511	ligase activity, forming carbon-carbon bonds
CLI14_01275	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CLI14_01280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLI14_01295	COG2814	Major facilitator Superfamily
CLI14_01300	COG2205	protein histidine kinase activity
CLI14_01300	COG2198	Histidine kinase
CLI14_01300	COG0784	Response regulator, receiver
CLI14_01305	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLI14_01315	COG3263	regulation of cellular component size
CLI14_01325	COG4232	protein-disulfide reductase activity
CLI14_01330	COG1438	arginine binding
CLI14_01335	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CLI14_01340	COG0540	Belongs to the ATCase OTCase family
CLI14_01350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CLI14_01355	COG0549	Belongs to the carbamate kinase family
CLI14_01365	COG1288	antiporter activity
CLI14_01375	COG1027	Aspartate ammonia-lyase
CLI14_01380	COG3030	protein affecting phage T7 exclusion by the F plasmid
CLI14_01385	COG1278	Cold shock
CLI14_01390	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CLI14_01395	COG2205	protein histidine kinase activity
CLI14_01400	COG0745	RESPONSE REGULATOR receiver
CLI14_01410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLI14_01415	COG0205	6-phosphofructokinase activity
CLI14_01420	COG1494	fructose-1,6-bisphosphatase
CLI14_01430	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CLI14_01435	COG0460	homoserine dehydrogenase
CLI14_01435	COG0527	aspartate kinase activity
CLI14_01440	COG0626	cystathionine gamma-synthase activity
CLI14_01450	COG0281	malic enzyme
CLI14_01460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLI14_01465	COG1609	Transcriptional regulator
CLI14_01485	COG1575	Belongs to the MenA family. Type 1 subfamily
CLI14_01490	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLI14_01495	COG0534	Mate efflux family protein
CLI14_01500	COG0149	triose-phosphate isomerase activity
CLI14_01530	COG0459	protein refolding
CLI14_01545	COG1509	lysine 2,3-aminomutase activity
CLI14_01550	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CLI14_01560	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CLI14_01565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CLI14_01570	COG1053	succinate dehydrogenase
CLI14_01575	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CLI14_01580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLI14_01590	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CLI14_01595	COG1045	serine acetyltransferase
CLI14_01615	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CLI14_01620	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CLI14_01630	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CLI14_01630	COG0165	Argininosuccinate lyase
CLI14_01640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLI14_01645	COG0678	peroxiredoxin activity
CLI14_01645	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CLI14_01655	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CLI14_01685	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLI14_01700	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CLI14_01705	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CLI14_01710	COG0546	phosphoglycolate phosphatase activity
CLI14_01715	COG0180	Tryptophanyl-tRNA synthetase
CLI14_01730	COG0583	DNA-binding transcription factor activity
CLI14_01740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLI14_01755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLI14_01775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLI14_01780	COG3954	Phosphoribulokinase
CLI14_01790	COG0429	hydrolase of the alpha beta-hydrolase fold
CLI14_01800	COG0488	(ABC) transporter
CLI14_01805	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLI14_01815	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CLI14_01820	COG1047	Peptidyl-prolyl cis-trans
CLI14_01830	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CLI14_01840	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CLI14_01845	COG0557	exoribonuclease II activity
CLI14_01850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLI14_01855	COG0051	transcription antitermination factor activity, RNA binding
CLI14_01880	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CLI14_01905	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CLI14_01910	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CLI14_01930	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CLI14_01935	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CLI14_01960	COG0201	protein transport
CLI14_01970	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CLI14_01975	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CLI14_01980	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CLI14_01990	COG0203	ribosomal protein L17
CLI14_01995	COG0545	Peptidyl-prolyl cis-trans isomerase
CLI14_02000	COG3266	domain, Protein
CLI14_02000	COG3061	Opacity-associated protein A
CLI14_02005	COG2153	protein acetylation
CLI14_02010	COG0513	Belongs to the DEAD box helicase family
CLI14_02050	COG0737	Belongs to the 5'-nucleotidase family
CLI14_02055	COG1648	precorrin-2 dehydrogenase activity
CLI14_02055	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CLI14_02060	COG0175	sulfate reduction
CLI14_02065	COG2895	sulfate adenylyltransferase (ATP) activity
CLI14_02070	COG0529	Catalyzes the synthesis of activated sulfate
CLI14_02105	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CLI14_02110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLI14_02115	COG0729	surface antigen
CLI14_02120	COG2911	Protein conserved in bacteria
CLI14_02125	COG2105	PFAM AIG2 family protein
CLI14_02135	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CLI14_02140	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CLI14_02145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CLI14_02150	COG0163	prenyltransferase activity
CLI14_02155	COG4143	(ABC) transporter
CLI14_02160	COG1178	ABC-type Fe3 transport system permease component
CLI14_02165	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CLI14_02170	COG3028	Belongs to the UPF0307 family
CLI14_02175	COG0312	modulator of DNA gyrase
CLI14_02180	COG2239	Acts as a magnesium transporter
CLI14_02185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI14_02195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI14_02200	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CLI14_02210	COG1137	ATPase activity
CLI14_02215	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CLI14_02225	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CLI14_02230	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CLI14_02230	COG0517	IMP dehydrogenase activity
CLI14_02240	COG1127	ABC transporter
CLI14_02245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CLI14_02250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CLI14_02255	COG2854	intermembrane phospholipid transfer
CLI14_02265	COG5007	Belongs to the BolA IbaG family
CLI14_02270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLI14_02275	COG0204	Acyl-transferase
CLI14_02290	COG0251	oxidation-reduction process
CLI14_02295	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CLI14_02310	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CLI14_02320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CLI14_02330	COG0564	pseudouridine synthase activity
CLI14_02335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLI14_02340	COG0525	valine-tRNA ligase activity
CLI14_02345	COG2927	DNA polymerase III (CHI subunit)
CLI14_02350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CLI14_02355	COG0795	lipopolysaccharide-transporting ATPase activity
CLI14_02360	COG0795	lipopolysaccharide-transporting ATPase activity
CLI14_02445	COG0066	3-isopropylmalate dehydratase activity
CLI14_02455	COG0473	3-isopropylmalate dehydrogenase activity
CLI14_02460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLI14_02475	COG0583	DNA-binding transcription factor activity
CLI14_02480	COG1022	Amp-dependent synthetase and ligase
CLI14_02485	COG0028	Belongs to the TPP enzyme family
CLI14_02495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLI14_02505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CLI14_02515	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CLI14_02525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLI14_02530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLI14_02545	COG0354	folic acid binding
CLI14_02550	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CLI14_02560	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CLI14_02565	COG1595	DNA-templated transcription, initiation
CLI14_02580	COG3086	response to oxidative stress
CLI14_02585	COG0481	GTPase activity
CLI14_02590	COG0681	Belongs to the peptidase S26 family
CLI14_02615	COG0736	holo-[acyl-carrier-protein] synthase activity
CLI14_02620	COG3437	response regulator, receiver
CLI14_02620	COG3850	Histidine kinase
CLI14_02620	COG2205	protein histidine kinase activity
CLI14_02620	COG4999	Histidine kinase
CLI14_02625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLI14_02630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLI14_02635	COG3956	TIGRFAM MazG family protein
CLI14_02640	COG0504	CTP synthase activity
CLI14_02650	COG0617	tRNA 3'-terminal CCA addition
CLI14_02655	COG3409	Peptidoglycan-binding domain 1 protein
CLI14_02655	COG3267	Type II secretory pathway component ExeA
CLI14_02665	COG4991	sh3 domain protein
CLI14_02670	COG0306	phosphate transporter
CLI14_02675	COG1392	Phosphate transport regulator
CLI14_02680	COG3025	triphosphatase activity
CLI14_02695	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CLI14_02705	COG1538	Outer membrane efflux protein
CLI14_02710	COG0494	nUDIX hydrolase
CLI14_02715	COG3151	Protein conserved in bacteria
CLI14_02725	COG3150	esterase
CLI14_02730	COG0187	DNA topoisomerase II activity
CLI14_02735	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLI14_02740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLI14_02745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLI14_02750	COG3105	Protein conserved in bacteria
CLI14_02755	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CLI14_02775	COG0723	plastoquinol--plastocyanin reductase activity
CLI14_02780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CLI14_02785	COG2857	Cytochrome c1
CLI14_02790	COG0625	glutathione transferase activity
CLI14_02795	COG2969	positive regulation of protein catabolic process
CLI14_02805	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CLI14_02815	COG3107	peptidoglycan biosynthetic process
CLI14_02820	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CLI14_02835	COG3116	cell division
CLI14_02840	COG0768	penicillin binding
CLI14_02845	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLI14_02850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CLI14_02855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLI14_02860	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CLI14_02865	COG0772	Belongs to the SEDS family
CLI14_02870	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLI14_02875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CLI14_02880	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CLI14_02885	COG0849	cell division
CLI14_02890	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CLI14_02895	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CLI14_02905	COG0653	protein targeting
CLI14_02910	COG0494	nUDIX hydrolase
CLI14_02920	COG0505	Belongs to the CarA family
CLI14_02930	COG0730	response to heat
CLI14_02935	COG0583	DNA-binding transcription factor activity
CLI14_02940	COG2860	membrane
CLI14_02945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLI14_02970	COG0493	'glutamate synthase
CLI14_02975	COG0067	glutamate synthase
CLI14_02975	COG0069	glutamate synthase activity
CLI14_02975	COG0070	glutamate synthase
CLI14_02985	COG0069	glutamate synthase activity
CLI14_02985	COG0070	glutamate synthase
CLI14_02985	COG0067	glutamate synthase
CLI14_02990	COG1242	4 iron, 4 sulfur cluster binding
CLI14_02995	COG0784	Response regulator, receiver
CLI14_02995	COG5002	protein histidine kinase activity
CLI14_02995	COG2198	Histidine kinase
CLI14_03005	COG0745	RESPONSE REGULATOR receiver
CLI14_03010	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLI14_03025	COG0083	homoserine kinase activity
CLI14_03030	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CLI14_03035	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CLI14_03040	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CLI14_03045	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CLI14_03060	COG1115	amino acid carrier protein
CLI14_03070	COG0084	hydrolase, TatD family'
CLI14_03075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLI14_03080	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CLI14_03090	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CLI14_03095	COG0813	purine-nucleoside phosphorylase activity
CLI14_03105	COG0560	Phosphoserine phosphatase
CLI14_03115	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CLI14_03120	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLI14_03125	COG4628	conserved protein (DUF2132)
CLI14_03130	COG1022	Amp-dependent synthetase and ligase
CLI14_03135	COG0784	Response regulator, receiver
CLI14_03135	COG3437	response regulator, receiver
CLI14_03150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CLI14_03155	COG1085	galactose-1-phosphate uridylyltransferase
CLI14_03165	COG1609	Transcriptional regulator
CLI14_03195	COG2171	N-acyltransferase activity
CLI14_03200	COG3141	response to X-ray
CLI14_03215	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CLI14_03220	COG1074	ATP-dependent DNA helicase activity
CLI14_03225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CLI14_03235	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CLI14_03235	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CLI14_03245	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CLI14_03250	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CLI14_03255	COG2166	iron-sulfur cluster assembly
CLI14_03260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLI14_03270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLI14_03285	COG1595	DNA-templated transcription, initiation
CLI14_03295	COG2211	Major facilitator Superfamily
CLI14_03315	COG0271	Belongs to the BolA IbaG family
CLI14_03350	COG1477	protein flavinylation
CLI14_03360	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLI14_03375	COG0733	neurotransmitter:sodium symporter activity
CLI14_03385	COG0189	ligase activity
CLI14_03390	COG4067	protein conserved in archaea
CLI14_03390	COG0189	ligase activity
CLI14_03395	COG2195	Cleaves the N-terminal amino acid of tripeptides
CLI14_03400	COG2252	PERMEase
CLI14_03420	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CLI14_03425	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CLI14_03435	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLI14_03435	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLI14_03460	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CLI14_03465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CLI14_03480	COG0024	Methionine aminopeptidase
CLI14_03485	COG0052	Belongs to the universal ribosomal protein uS2 family
CLI14_03490	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CLI14_03500	COG0233	cytoplasmic translational termination
CLI14_03505	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CLI14_03510	COG0575	Belongs to the CDS family
CLI14_03515	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CLI14_03520	COG0750	zinc metalloprotease
CLI14_03530	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CLI14_03535	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLI14_03540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLI14_03550	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLI14_03560	COG0587	DNA-directed DNA polymerase activity
CLI14_03565	COG0825	malonyl-CoA metabolic process
CLI14_03570	COG0037	tRNA processing
CLI14_03580	COG0347	Belongs to the P(II) protein family
CLI14_03595	COG1388	LysM domain
CLI14_03595	COG0741	lytic transglycosylase activity
CLI14_03600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLI14_03605	COG2226	methyltransferase
CLI14_03615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CLI14_03630	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CLI14_03635	COG0121	glutamine amidotransferase
CLI14_03640	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CLI14_03645	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CLI14_03650	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CLI14_03655	COG1187	pseudouridine synthase activity
CLI14_03680	COG2608	mercury ion transmembrane transporter activity
CLI14_03680	COG2217	Heavy metal translocating P-type atpase
CLI14_03725	COG2747	anti-sigma28 factor FlgM
CLI14_03735	COG0784	Response regulator, receiver
CLI14_03735	COG0835	chemotaxis
CLI14_03745	COG1815	bacterial-type flagellum-dependent cell motility
CLI14_03750	COG1558	bacterial-type flagellum-dependent cell motility
CLI14_03755	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CLI14_03760	COG1749	Flagellar hook protein flgE
CLI14_03765	COG4787	bacterial-type flagellum-dependent cell motility
CLI14_03770	COG4786	Flagellar basal body rod
CLI14_03775	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CLI14_03780	COG1706	bacterial-type flagellum-dependent cell motility
CLI14_03785	COG3951	Flagellar rod assembly protein muramidase FlgJ
CLI14_03785	COG1705	Flagellar rod assembly protein muramidase FlgJ
CLI14_03795	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CLI14_03890	COG0193	aminoacyl-tRNA hydrolase activity
CLI14_03905	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CLI14_03910	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CLI14_03915	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CLI14_03920	COG2890	protein-(glutamine-N5) methyltransferase activity
CLI14_03925	COG3094	Invasion gene expression up-regulator, SirB
CLI14_03930	COG2912	Transglutaminase-like superfamily
CLI14_03935	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CLI14_03945	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLI14_03950	COG2233	PERMEase
CLI14_03970	COG1393	Belongs to the ArsC family
CLI14_03975	COG4783	chaperone-mediated protein folding
CLI14_03995	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CLI14_04005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLI14_04025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CLI14_04030	COG1393	Belongs to the ArsC family
CLI14_04055	COG2837	iron assimilation
CLI14_04080	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CLI14_04090	COG1516	flagellar protein fliS
CLI14_04100	COG4191	Histidine kinase
CLI14_04105	COG2204	response regulator
CLI14_04110	COG1677	Flagellar hook-basal body complex protein FliE
CLI14_04120	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLI14_04170	COG1987	bacterial-type flagellum assembly
CLI14_04175	COG1684	flagellar biosynthetic protein fliR
CLI14_04185	COG2840	Smr protein MutS2
CLI14_04190	COG2890	protein-(glutamine-N5) methyltransferase activity
CLI14_04195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CLI14_04200	COG2860	membrane
CLI14_04205	COG3101	peptidyl-lysine hydroxylation
CLI14_04215	COG0431	NADPH-dependent FMN reductase
CLI14_04220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLI14_04220	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CLI14_04225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLI14_04230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLI14_04235	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLI14_04240	COG0735	belongs to the Fur family
CLI14_04250	COG0583	DNA-binding transcription factor activity
CLI14_04260	COG1346	cytolysis
CLI14_04265	COG0716	FMN binding
CLI14_04275	COG0596	Alpha beta hydrolase
CLI14_04280	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CLI14_04285	COG0033	Phosphoglucomutase
CLI14_04295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CLI14_04305	COG2009	succinate dehydrogenase
CLI14_04310	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CLI14_04325	COG0567	Dehydrogenase, E1 component
CLI14_04330	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLI14_04345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLI14_04350	COG1121	(ABC) transporter
CLI14_04355	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CLI14_04360	COG4977	sequence-specific DNA binding
CLI14_04365	COG1918	ferrous iron import across plasma membrane
CLI14_04390	COG3102	Protein conserved in bacteria
CLI14_04395	COG1025	Belongs to the peptidase M16 family
CLI14_04400	COG2062	phosphohistidine phosphatase, SixA
CLI14_04405	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLI14_04415	COG0455	bacterial-type flagellum organization
CLI14_04430	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CLI14_04435	COG0643	Histidine kinase
CLI14_04435	COG2198	Histidine kinase
CLI14_04440	COG2201	protein-glutamate methylesterase activity
CLI14_04445	COG1192	Involved in chromosome partitioning
CLI14_04455	COG0835	chemotaxis
CLI14_04465	COG4133	protoheme IX ABC transporter activity
CLI14_04470	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLI14_04475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLI14_04485	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CLI14_04490	COG1138	Cytochrome C-type biogenesis protein
CLI14_04495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLI14_04510	COG2853	Lipoprotein
CLI14_04530	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CLI14_04535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLI14_04550	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CLI14_04555	COG0243	molybdopterin cofactor binding
CLI14_04565	COG3083	sulfuric ester hydrolase activity
CLI14_04570	COG3082	Protein of unknown function (DUF1414)
CLI14_04585	COG1757	Na H antiporter
CLI14_04590	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLI14_04595	COG2095	MarC family integral membrane protein
CLI14_04600	COG1012	belongs to the aldehyde dehydrogenase family
CLI14_04600	COG1454	alcohol dehydrogenase
CLI14_04610	COG1530	ribonuclease E activity
CLI14_04615	COG0564	pseudouridine synthase activity
CLI14_04620	COG0424	maF-like protein
CLI14_04625	COG1399	metal-binding, possibly nucleic acid-binding protein
CLI14_04630	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CLI14_04640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLI14_04665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLI14_04670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CLI14_04675	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CLI14_04680	COG0470	DNA polymerase III
CLI14_04685	COG0084	hydrolase, TatD family'
CLI14_04690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLI14_04690	COG1263	PTS System
CLI14_04700	COG0733	neurotransmitter:sodium symporter activity
CLI14_04715	COG4667	esterase of the alpha-beta hydrolase superfamily
CLI14_04725	COG1940	carbohydrate kinase activity
CLI14_04730	COG0784	Response regulator, receiver
CLI14_04730	COG0835	chemotaxis
CLI14_04735	COG1028	Short-chain dehydrogenase reductase Sdr
CLI14_04740	COG0616	signal peptide processing
CLI14_04755	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CLI14_04760	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CLI14_04765	COG0436	Aminotransferase
CLI14_04775	COG1169	isochorismate synthase
CLI14_04780	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CLI14_04790	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CLI14_04795	COG1441	menaquinone biosynthetic process
CLI14_04840	COG1522	sequence-specific DNA binding
CLI14_04845	COG1946	Acyl-CoA thioesterase
CLI14_04850	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CLI14_04865	COG3706	GGDEF domain
CLI14_04890	COG1022	Amp-dependent synthetase and ligase
CLI14_04900	COG4221	oxidoreductase activity
CLI14_04910	COG0745	RESPONSE REGULATOR receiver
CLI14_04915	COG0642	Histidine kinase
CLI14_04920	COG2194	sulfuric ester hydrolase activity
CLI14_04935	COG2985	domain, Protein
CLI14_04945	COG3850	Histidine kinase
CLI14_04945	COG5002	protein histidine kinase activity
CLI14_04960	COG1609	Transcriptional regulator
CLI14_04965	COG0129	dihydroxy-acid dehydratase activity
CLI14_04970	COG3265	gluconokinase activity
CLI14_04975	COG2610	gluconate transmembrane transporter activity
CLI14_04980	COG0800	Aldolase
CLI14_05005	COG1028	Short-chain dehydrogenase reductase Sdr
CLI14_05010	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLI14_05015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLI14_05045	COG1216	Glycosyl transferase, family 2
CLI14_05065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLI14_05070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLI14_05095	COG5002	protein histidine kinase activity
CLI14_05095	COG0784	Response regulator, receiver
CLI14_05110	COG0601	transmembrane transport
CLI14_05115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLI14_05120	COG0444	Belongs to the ABC transporter superfamily
CLI14_05130	COG0435	Glutathione S-transferase
CLI14_05135	COG0280	phosphate acetyltransferase
CLI14_05135	COG0857	belongs to the CobB CobQ family
CLI14_05140	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CLI14_05145	COG3092	negative regulation of chromosome organization
CLI14_05155	COG4120	Belongs to the binding-protein-dependent transport system permease family
CLI14_05165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLI14_05170	COG0653	protein targeting
CLI14_05175	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CLI14_05180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CLI14_05190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CLI14_05200	COG0156	8-amino-7-oxononanoate synthase activity
CLI14_05205	COG2226	methyltransferase
CLI14_05210	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CLI14_05220	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CLI14_05225	COG2186	Transcriptional regulator
CLI14_05240	COG0537	adenosine 5'-monophosphoramidase activity
CLI14_05270	COG1252	NADH dehydrogenase
CLI14_05285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CLI14_05295	COG4591	ABC-type transport system involved in lipoprotein release permease component
CLI14_05300	COG1136	(ABC) transporter
CLI14_05305	COG4591	ABC-type transport system involved in lipoprotein release permease component
CLI14_05315	COG0658	competence protein
CLI14_05315	COG2333	competence protein COMEC
CLI14_05320	COG1132	(ABC) transporter
CLI14_05335	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CLI14_05345	COG2719	SpoVR family
CLI14_05350	COG2718	Belongs to the UPF0229 family
CLI14_05355	COG2766	serine protein kinase
CLI14_05370	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CLI14_05385	COG1882	Formate acetyltransferase
CLI14_05410	COG4215	(ABC) transporter
CLI14_05415	COG4160	amino acid transport
CLI14_05420	COG0708	Exodeoxyribonuclease III
CLI14_05425	COG0840	transmembrane signaling receptor activity
CLI14_05435	COG3923	Primosomal replication protein n
CLI14_05445	COG1199	ATP-dependent helicase activity
CLI14_05455	COG3012	SEC-C Motif Domain Protein
CLI14_05460	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CLI14_05465	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLI14_05470	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLI14_05475	COG0215	cysteine-tRNA ligase activity
CLI14_05480	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CLI14_05485	COG0632	four-way junction helicase activity
CLI14_05490	COG2255	four-way junction helicase activity
CLI14_05495	COG1271	oxidase subunit
CLI14_05500	COG1294	oxidase, subunit
CLI14_05505	COG4890	Cyd operon protein YbgT
CLI14_05510	COG3790	cyd operon protein YbgE
CLI14_05515	COG0824	Thioesterase
CLI14_05520	COG0811	peptide transport
CLI14_05540	COG2885	chlorophyll binding
CLI14_05545	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CLI14_05555	COG2433	Pfam Transposase IS66
CLI14_05575	COG0784	Response regulator, receiver
CLI14_05575	COG5002	protein histidine kinase activity
CLI14_05590	COG0582	viral genome integration into host DNA
CLI14_05605	COG1401	restriction endodeoxyribonuclease activity
CLI14_05625	COG3300	MHYT domain
CLI14_05625	COG5001	Diguanylate cyclase
CLI14_05650	COG1960	acyl-CoA dehydrogenase activity
CLI14_05655	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CLI14_05685	COG0247	lactate metabolic process
CLI14_05685	COG0277	FAD linked oxidase domain protein
CLI14_05700	COG2986	histidine ammonia-lyase
CLI14_05710	COG0010	Belongs to the arginase family
CLI14_05715	COG1228	amidohydrolase
CLI14_05730	COG3099	Belongs to the UPF0263 family
CLI14_05735	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CLI14_05745	COG0417	DNA replication proofreading
CLI14_05750	COG2197	response regulator
CLI14_05755	COG0322	excinuclease ABC activity
CLI14_05800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLI14_05800	COG0072	phenylalanine-tRNA ligase activity
CLI14_05815	COG0500	methyltransferase
CLI14_05825	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CLI14_05830	COG5001	Diguanylate cyclase
CLI14_05835	COG0295	cytidine deaminase activity
CLI14_05840	COG1346	cytolysis
CLI14_05850	COG2925	Exonuclease
CLI14_05860	COG0702	epimerase
CLI14_05890	COG2994	toxin metabolic process
CLI14_05895	COG3064	Membrane
CLI14_05895	COG1073	alpha beta
CLI14_05895	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CLI14_05905	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CLI14_05920	COG2988	succinylglutamate desuccinylase activity
CLI14_05925	COG4139	cobalamin transport
CLI14_05950	COG0583	DNA-binding transcription factor activity
CLI14_05960	COG1451	nucleotide metabolic process
CLI14_05975	COG3063	Type IV pilus biogenesis stability protein PilW
CLI14_06000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLI14_06015	COG3290	protein histidine kinase activity
CLI14_06020	COG4565	transcriptional regulatory protein
CLI14_06030	COG0784	Response regulator, receiver
CLI14_06030	COG0835	chemotaxis
CLI14_06045	COG0745	RESPONSE REGULATOR receiver
CLI14_06045	COG3706	GGDEF domain
CLI14_06070	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CLI14_06095	COG3501	Rhs element vgr protein
CLI14_06145	COG1181	Belongs to the D-alanine--D-alanine ligase family
CLI14_06165	COG1716	ATPase activity
CLI14_06190	COG0515	serine threonine protein kinase
CLI14_06190	COG3064	Membrane
CLI14_06190	COG4991	sh3 domain protein
CLI14_06240	COG2433	Pfam Transposase IS66
CLI14_06260	COG0251	oxidation-reduction process
CLI14_06270	COG1294	oxidase, subunit
CLI14_06290	COG3220	belongs to the UPF0276 family
CLI14_06315	COG0840	transmembrane signaling receptor activity
CLI14_06325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CLI14_06330	COG2200	EAL domain
CLI14_06335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLI14_06340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLI14_06340	COG1263	PTS System
CLI14_06350	COG1621	beta-fructofuranosidase activity
CLI14_06355	COG0840	transmembrane signaling receptor activity
CLI14_06370	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CLI14_06375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLI14_06385	COG0848	biopolymer transport protein
CLI14_06390	COG0811	peptide transport
CLI14_06395	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CLI14_06400	COG3721	Heme iron utilization protein
CLI14_06405	COG0748	coenzyme F420 binding
CLI14_06410	COG1629	transport
CLI14_06410	COG4771	TonB-dependent receptor
CLI14_06415	COG1940	carbohydrate kinase activity
CLI14_06445	COG2989	Protein conserved in bacteria
CLI14_06450	COG3108	Peptidase M15
CLI14_06455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLI14_06470	COG1846	Transcriptional regulator
CLI14_06475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CLI14_06490	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CLI14_06495	COG1448	Aminotransferase
CLI14_06500	COG2770	Histidine kinase
CLI14_06500	COG3437	response regulator, receiver
CLI14_06505	COG0840	transmembrane signaling receptor activity
CLI14_06510	COG0745	RESPONSE REGULATOR receiver
CLI14_06520	COG0643	Histidine kinase
CLI14_06520	COG2198	Histidine kinase
CLI14_06530	COG0835	chemotaxis
CLI14_06535	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CLI14_06540	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CLI14_06545	COG2201	protein-glutamate methylesterase activity
CLI14_06555	COG0017	Asparaginyl-tRNA synthetase
CLI14_06560	COG0840	transmembrane signaling receptor activity
CLI14_06565	COG0720	synthase
CLI14_06570	COG2356	endonuclease I
CLI14_06580	COG1760	l-serine dehydratase
CLI14_06585	COG0814	amino acid
CLI14_06590	COG0494	nUDIX hydrolase
CLI14_06595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CLI14_06610	COG3106	COG3106 Predicted ATPase
CLI14_06615	COG3768	UPF0283 membrane protein
CLI14_06620	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CLI14_06625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLI14_06635	COG3706	GGDEF domain
CLI14_06645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLI14_06655	COG0471	metal ion transport
CLI14_06660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLI14_06660	COG4191	Histidine kinase
CLI14_06675	COG1278	Cold shock
CLI14_06680	COG3005	denitrification pathway
CLI14_06685	COG0243	molybdopterin cofactor binding
CLI14_06690	COG0513	Belongs to the DEAD box helicase family
CLI14_06695	COG2723	6-phospho-beta-galactosidase activity
CLI14_06700	COG1609	Transcriptional regulator
CLI14_06730	COG0443	Heat shock 70 kDa protein
CLI14_06770	COG1643	Atp-dependent helicase
CLI14_06780	COG0583	DNA-binding transcription factor activity
CLI14_06785	COG0477	Major facilitator Superfamily
CLI14_06805	COG0673	inositol 2-dehydrogenase activity
CLI14_06810	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLI14_06815	COG0517	IMP dehydrogenase activity
CLI14_06815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CLI14_06820	COG2176	DNA-directed DNA polymerase activity
CLI14_06830	COG3718	enzyme involved in inositol metabolism
CLI14_06835	COG3962	Belongs to the TPP enzyme family
CLI14_06840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLI14_06865	COG0673	inositol 2-dehydrogenase activity
CLI14_06870	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CLI14_06895	COG2433	Pfam Transposase IS66
CLI14_06910	COG1204	response to ionizing radiation
CLI14_06930	COG2433	Pfam Transposase IS66
CLI14_06940	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CLI14_06945	COG1280	lysine exporter protein (LysE YggA)
CLI14_06950	COG1115	amino acid carrier protein
CLI14_06965	COG2195	Cleaves the N-terminal amino acid of tripeptides
CLI14_06975	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CLI14_06985	COG0625	glutathione transferase activity
CLI14_07015	COG0811	peptide transport
CLI14_07020	COG0811	peptide transport
CLI14_07025	COG0848	biopolymer transport protein
CLI14_07040	COG4667	esterase of the alpha-beta hydrolase superfamily
CLI14_07045	COG1793	dna ligase
CLI14_07070	COG0791	NLP P60 protein
CLI14_07075	COG0840	transmembrane signaling receptor activity
CLI14_07100	COG1763	Mo-molybdopterin cofactor biosynthetic process
CLI14_07105	COG0746	molybdenum cofactor guanylyltransferase activity
CLI14_07110	COG3842	ATPase activity
CLI14_07120	COG1840	ABC-type Fe3 transport system, periplasmic component
CLI14_07125	COG2271	Major facilitator Superfamily
CLI14_07135	COG2197	response regulator
CLI14_07140	COG0488	(ABC) transporter
CLI14_07145	COG0004	ammonium transporteR
CLI14_07150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CLI14_07155	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CLI14_07160	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CLI14_07165	COG1177	transmembrane transport
CLI14_07170	COG1176	ABC-type spermidine putrescine transport system, permease component I
CLI14_07175	COG3842	ATPase activity
CLI14_07200	COG0589	response to stress
CLI14_07205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLI14_07220	COG2217	Heavy metal translocating P-type atpase
CLI14_07230	COG2010	Cytochrome c
CLI14_07245	COG3278	Belongs to the heme-copper respiratory oxidase family
CLI14_07275	COG3120	sequence-specific DNA binding
CLI14_07280	COG1067	ATP-dependent peptidase activity
CLI14_07285	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLI14_07310	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CLI14_07310	COG0116	Belongs to the methyltransferase superfamily
CLI14_07320	COG0167	dihydroorotate dehydrogenase activity
CLI14_07325	COG2902	Dehydrogenase
CLI14_07335	COG0308	aminopeptidase N
CLI14_07355	COG1956	GAF domain-containing protein
CLI14_07360	COG1132	(ABC) transporter
CLI14_07365	COG2995	paraquat-inducible protein a
CLI14_07370	COG3008	intermembrane lipid transfer
CLI14_07380	COG2996	Protein conserved in bacteria
CLI14_07400	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLI14_07415	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CLI14_07415	COG1648	precorrin-2 dehydrogenase activity
CLI14_07420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLI14_07425	COG4597	amino acid ABC transporter
CLI14_07430	COG0765	amino acid transport
CLI14_07435	COG1126	abc transporter atp-binding protein
CLI14_07440	COG0670	Belongs to the BI1 family
CLI14_07445	COG2920	part of a sulfur-relay system
CLI14_07450	COG1254	Belongs to the acylphosphatase family
CLI14_07495	COG0602	queuosine metabolic process
CLI14_07500	COG0561	phosphatase activity
CLI14_07520	COG2828	Protein conserved in bacteria
CLI14_07525	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CLI14_07530	COG0372	Belongs to the citrate synthase family
CLI14_07535	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CLI14_07565	COG0745	RESPONSE REGULATOR receiver
CLI14_07570	COG5002	protein histidine kinase activity
CLI14_07575	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CLI14_07580	COG1902	pentaerythritol trinitrate reductase activity
CLI14_07585	COG0583	DNA-binding transcription factor activity
CLI14_07595	COG1129	ABC transporter
CLI14_07615	COG1342	Belongs to the UPF0251 family
CLI14_07625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLI14_07635	COG2207	Transcriptional regulator
CLI14_07640	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLI14_07640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLI14_07640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI14_07665	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CLI14_07670	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
CLI14_07675	COG3051	citrate lyase alpha subunit
CLI14_07680	COG2301	Belongs to the HpcH HpaI aldolase family
CLI14_07685	COG3052	prosthetic group binding
CLI14_07690	COG4565	transcriptional regulatory protein
CLI14_07700	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CLI14_07705	COG5016	pyruvate
CLI14_07705	COG0511	ligase activity, forming carbon-carbon bonds
CLI14_07720	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CLI14_07760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CLI14_07765	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLI14_07770	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLI14_07800	COG0840	transmembrane signaling receptor activity
CLI14_07805	COG0019	diaminopimelate decarboxylase activity
CLI14_07825	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CLI14_07840	COG4181	ATPase activity
CLI14_07845	COG0534	Mate efflux family protein
CLI14_07850	COG0702	epimerase
CLI14_07860	COG2814	Major facilitator Superfamily
CLI14_07865	COG1187	pseudouridine synthase activity
CLI14_07870	COG1061	Type III restriction enzyme res subunit
CLI14_07885	COG2205	protein histidine kinase activity
CLI14_07905	COG0513	Belongs to the DEAD box helicase family
CLI14_07935	COG3313	Fe-S protein
CLI14_07945	COG4134	Bacterial extracellular solute-binding protein
CLI14_07950	COG4135	transport system, permease component
CLI14_07955	COG4136	ATPase activity
CLI14_07960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLI14_07985	COG0564	pseudouridine synthase activity
CLI14_07990	COG0733	neurotransmitter:sodium symporter activity
CLI14_08000	COG0626	cystathionine gamma-synthase activity
CLI14_08005	COG0519	Catalyzes the synthesis of GMP from XMP
CLI14_08020	COG1842	Phage shock protein A
CLI14_08025	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CLI14_08035	COG4168	peptide transport system, permease
CLI14_08040	COG4171	peptide transport system, permease
CLI14_08050	COG4172	Belongs to the ABC transporter superfamily
CLI14_08065	COG1227	inorganic diphosphatase activity
CLI14_08075	COG0243	molybdopterin cofactor binding
CLI14_08080	COG3005	denitrification pathway
CLI14_08085	COG4459	periplasmic nitrate reductase
CLI14_08090	COG2116	formate transmembrane transporter activity
CLI14_08115	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CLI14_08120	COG1435	thymidine kinase activity
CLI14_08125	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CLI14_08130	COG1801	Protein of unknown function DUF72
CLI14_08140	COG4106	trans-aconitate 2-methyltransferase activity
CLI14_08150	COG4067	protein conserved in archaea
CLI14_08150	COG0189	ligase activity
CLI14_08165	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CLI14_08170	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CLI14_08180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CLI14_08185	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CLI14_08190	COG0745	RESPONSE REGULATOR receiver
CLI14_08200	COG1609	Transcriptional regulator
CLI14_08205	COG3070	regulator of competence-specific genes
CLI14_08225	COG0297	glycogen (starch) synthase activity
CLI14_08230	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CLI14_08235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLI14_08245	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CLI14_08250	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CLI14_08255	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CLI14_08260	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CLI14_08265	COG0542	response to heat
CLI14_08270	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CLI14_08275	COG1278	Cold shock
CLI14_08285	COG1187	pseudouridine synthase activity
CLI14_08290	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CLI14_08290	COG0140	phosphoribosyl-ATP diphosphatase activity
CLI14_08295	COG0107	imidazoleglycerol-phosphate synthase activity
CLI14_08300	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CLI14_08305	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CLI14_08310	COG0131	Imidazoleglycerol-phosphate dehydratase
CLI14_08310	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CLI14_08315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLI14_08320	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CLI14_08330	COG1757	Na H antiporter
CLI14_08335	COG2916	Histone family protein nucleoid-structuring protein H-NS
CLI14_08340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLI14_08350	COG0482	sulfurtransferase activity
CLI14_08355	COG2915	High frequency lysogenization protein hflD homolog
CLI14_08360	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CLI14_08365	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CLI14_08375	COG4191	Histidine kinase
CLI14_08375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLI14_08390	COG3070	regulator of competence-specific genes
CLI14_08400	COG2431	L-lysine efflux transmembrane transporter activity
CLI14_08410	COG0076	glutamate decarboxylase activity
CLI14_08415	COG1737	Transcriptional regulator
CLI14_08425	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CLI14_08445	COG0281	malic enzyme
CLI14_08455	COG2949	membrane
CLI14_08470	COG0745	RESPONSE REGULATOR receiver
CLI14_08470	COG3706	GGDEF domain
CLI14_08475	COG0492	ferredoxin-NADP+ reductase activity
CLI14_08480	COG4988	ABC transporter
CLI14_08485	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CLI14_08500	COG1595	DNA-templated transcription, initiation
CLI14_08515	COG1187	pseudouridine synthase activity
CLI14_08520	COG0009	L-threonylcarbamoyladenylate synthase
CLI14_08525	COG0613	PHP domain protein
CLI14_08535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CLI14_08540	COG0512	Glutamine amidotransferase of anthranilate synthase
CLI14_08545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CLI14_08550	COG0135	phosphoribosylanthranilate isomerase activity
CLI14_08550	COG0134	indole-3-glycerol-phosphate synthase activity
CLI14_08555	COG0133	tryptophan synthase activity
CLI14_08585	COG1607	acyl-coa hydrolase
CLI14_08590	COG2350	Protein conserved in bacteria
CLI14_08600	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CLI14_08605	COG0583	DNA-binding transcription factor activity
CLI14_08620	COG2200	EAL domain
CLI14_08620	COG2199	diguanylate cyclase activity
CLI14_08620	COG2203	Gaf domain
CLI14_08630	COG1032	radical SAM domain protein
CLI14_08640	COG2268	Band 7 protein
CLI14_08650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CLI14_08665	COG0300	oxidoreductase activity
CLI14_08675	COG0501	Belongs to the peptidase M48B family
CLI14_08685	COG1674	ftsk spoiiie
CLI14_08690	COG1522	sequence-specific DNA binding
CLI14_08695	COG0686	Belongs to the AlaDH PNT family
CLI14_08705	COG0583	DNA-binding transcription factor activity
CLI14_08720	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CLI14_08725	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CLI14_08735	COG0539	negative regulation of cytoplasmic translation
CLI14_08740	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CLI14_08745	COG1555	photosystem II stabilization
CLI14_08750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLI14_08755	COG0776	regulation of translation
CLI14_08760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CLI14_08775	COG0544	peptidyl-prolyl cis-trans isomerase activity
CLI14_08795	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CLI14_08800	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CLI14_08805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CLI14_08815	COG1653	transport
CLI14_08820	COG2205	protein histidine kinase activity
CLI14_08825	COG0745	RESPONSE REGULATOR receiver
CLI14_08830	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CLI14_08835	COG1760	l-serine dehydratase
CLI14_08845	COG0513	Belongs to the DEAD box helicase family
CLI14_08855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CLI14_08870	COG4628	conserved protein (DUF2132)
CLI14_08895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLI14_08900	COG0583	DNA-binding transcription factor activity
CLI14_08905	COG2951	lytic endotransglycosylase activity
CLI14_08910	COG3100	YcgL domain-containing protein
CLI14_08920	COG2894	cell division
CLI14_08930	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CLI14_08935	COG0318	PFAM AMP-dependent synthetase and ligase
CLI14_08940	COG0596	Alpha beta hydrolase
CLI14_08955	COG1214	PFAM Peptidase M22, glycoprotease
CLI14_08960	COG1199	ATP-dependent helicase activity
CLI14_08970	COG0788	formyltetrahydrofolate deformylase activity
CLI14_08975	COG1902	pentaerythritol trinitrate reductase activity
CLI14_08975	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLI14_08980	COG0616	signal peptide processing
CLI14_08985	COG0252	asparaginase activity
CLI14_08990	COG3139	Protein of unknown function (DUF1315)
CLI14_09000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLI14_09015	COG2226	methyltransferase
CLI14_09045	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CLI14_09055	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLI14_09060	COG2832	Protein of unknown function (DUF454)
CLI14_09070	COG0745	RESPONSE REGULATOR receiver
CLI14_09075	COG0583	DNA-binding transcription factor activity
CLI14_09080	COG0778	Nitroreductase
CLI14_09085	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLI14_09085	COG1024	Enoyl-CoA hydratase
CLI14_09090	COG0183	Belongs to the thiolase family
CLI14_09105	COG1595	DNA-templated transcription, initiation
CLI14_09115	COG2067	long-chain fatty acid transport protein
CLI14_09120	COG2067	long-chain fatty acid transport protein
CLI14_09125	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CLI14_09130	COG2982	Protein involved in outer membrane biogenesis
CLI14_09135	COG0572	uridine kinase
CLI14_09140	COG0489	protein tyrosine kinase activity
CLI14_09145	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLI14_09145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLI14_09155	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CLI14_09165	COG4109	DRTGG domain
CLI14_09170	COG2199	diguanylate cyclase activity
CLI14_09175	COG0314	molybdopterin synthase activity
CLI14_09180	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CLI14_09190	COG0521	Mo-molybdopterin cofactor biosynthetic process
CLI14_09195	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CLI14_09200	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CLI14_09205	COG2198	Histidine kinase
CLI14_09210	COG2204	response regulator
CLI14_09215	COG0556	nucleotide-excision repair
CLI14_09230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLI14_09235	COG1028	Short-chain dehydrogenase reductase Sdr
CLI14_09240	COG1169	isochorismate synthase
CLI14_09245	COG1021	2,3-dihydroxybenzoate-AMP ligase
CLI14_09250	COG1535	isochorismatase
CLI14_09250	COG3433	isochorismatase activity
CLI14_09280	COG2382	esterase
CLI14_09285	COG1629	transport
CLI14_09285	COG4774	siderophore transport
CLI14_09295	COG4657	Part of a membrane complex involved in electron transport
CLI14_09300	COG2878	Part of a membrane complex involved in electron transport
CLI14_09305	COG4656	Part of a membrane complex involved in electron transport
CLI14_09310	COG4658	electron transport chain
CLI14_09325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CLI14_09330	COG0346	lactoylglutathione lyase activity
CLI14_09340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CLI14_09345	COG2056	Na+-H+ antiporter family
CLI14_09350	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CLI14_09355	COG1286	toxin biosynthetic process
CLI14_09360	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CLI14_09365	COG0285	dihydrofolate synthase activity
CLI14_09385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLI14_09390	COG2190	(PTS) system
CLI14_09390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLI14_09390	COG1263	PTS System
CLI14_09395	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CLI14_09400	COG1940	carbohydrate kinase activity
CLI14_09400	COG1846	Transcriptional regulator
CLI14_09405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CLI14_09405	COG4651	solute:proton antiporter activity
CLI14_09410	COG0367	asparagine synthase
CLI14_09420	COG3104	oligopeptide transport
CLI14_09425	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CLI14_09435	COG0326	Molecular chaperone. Has ATPase activity
CLI14_09440	COG3710	Transcriptional regulator
CLI14_09455	COG0622	Phosphoesterase
CLI14_09460	COG1090	epimerase
CLI14_09465	COG3118	belongs to the thioredoxin family
CLI14_09470	COG0330	HflC and HflK could
CLI14_09480	COG0789	Transcriptional regulator
CLI14_09505	COG3115	cell septum assembly
CLI14_09510	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CLI14_09515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CLI14_09520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI14_09525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLI14_09530	COG2190	(PTS) system
CLI14_09535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLI14_09540	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLI14_09545	COG1702	phosphate starvation-inducible protein PhoH
CLI14_09555	COG4535	Mg2 and Co2 transporter CorC
CLI14_09560	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CLI14_09565	COG2888	peptidyl-tyrosine sulfation
CLI14_09570	COG0495	leucyl-tRNA aminoacylation
CLI14_09575	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CLI14_09580	COG1466	dna polymerase III delta subunit
CLI14_09585	COG0799	negative regulation of ribosome biogenesis
CLI14_09590	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CLI14_09595	COG0768	penicillin binding
CLI14_09600	COG0772	Belongs to the SEDS family
CLI14_09605	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CLI14_09610	COG1686	Belongs to the peptidase S11 family
CLI14_09615	COG2921	Belongs to the UPF0250 family
CLI14_09620	COG0321	lipoyl(octanoyl) transferase activity
CLI14_09635	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CLI14_09655	COG1596	polysaccharide export
CLI14_09660	COG0489	protein tyrosine kinase activity
CLI14_09690	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CLI14_09700	COG1045	serine acetyltransferase
CLI14_09740	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CLI14_09745	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CLI14_09750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLI14_09755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLI14_09760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLI14_09795	COG2205	protein histidine kinase activity
CLI14_09800	COG0745	RESPONSE REGULATOR receiver
CLI14_09805	COG0366	Alpha amylase catalytic
CLI14_09810	COG1263	PTS System
CLI14_09810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLI14_09825	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CLI14_09830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLI14_09835	COG2011	ABC-type metal ion transport system permease component
CLI14_09840	COG1464	Belongs to the NlpA lipoprotein family
CLI14_09845	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CLI14_09865	COG3706	GGDEF domain
CLI14_09870	COG1611	Belongs to the LOG family
CLI14_09875	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLI14_09885	COG2363	Small membrane protein
CLI14_09890	COG0583	DNA-binding transcription factor activity
CLI14_09895	COG0301	tRNA thio-modification
CLI14_09895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLI14_09905	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CLI14_09915	COG0142	geranyltranstransferase activity
CLI14_09920	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CLI14_09925	COG0564	pseudouridine synthase activity
CLI14_09930	COG3098	single-species biofilm formation
CLI14_09960	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CLI14_09970	COG1720	tRNA m6t6A37 methyltransferase activity
CLI14_09975	COG0442	prolyl-tRNA aminoacylation
CLI14_09980	COG2979	Protein of unknown function (DUF533)
CLI14_10000	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLI14_10000	COG0047	phosphoribosylformylglycinamidine synthase activity
CLI14_10010	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CLI14_10015	COG0590	tRNA wobble adenosine to inosine editing
CLI14_10020	COG0583	DNA-binding transcription factor activity
CLI14_10030	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CLI14_10035	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CLI14_10065	COG0484	heat shock protein binding
CLI14_10070	COG0443	Heat shock 70 kDa protein
CLI14_10075	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CLI14_10080	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLI14_10095	COG0497	DNA recombination
CLI14_10100	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLI14_10105	COG2914	Belongs to the UPF0125 (RnfH) family
CLI14_10110	COG2867	negative regulation of translational initiation
CLI14_10125	COG0582	viral genome integration into host DNA
CLI14_10130	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CLI14_10150	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CLI14_10155	COG1715	Restriction endonuclease
CLI14_10170	COG2003	Belongs to the UPF0758 family
CLI14_10295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLI14_10300	COG1115	amino acid carrier protein
CLI14_10305	COG1584	GPR1 FUN34 yaaH family protein
CLI14_10315	COG0351	phosphomethylpyrimidine kinase
CLI14_10320	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CLI14_10320	COG0519	Catalyzes the synthesis of GMP from XMP
CLI14_10325	COG0517	IMP dehydrogenase activity
CLI14_10325	COG0516	GMP reductase activity
CLI14_10340	COG1160	GTP binding
CLI14_10345	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLI14_10350	COG2976	Protein conserved in bacteria
CLI14_10355	COG0124	histidyl-tRNA synthetase
CLI14_10360	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CLI14_10365	COG1426	Protein conserved in bacteria
CLI14_10380	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CLI14_10385	COG2975	iron-sulfur cluster assembly
CLI14_10390	COG0633	Ferredoxin
CLI14_10395	COG0443	Heat shock 70 kDa protein
CLI14_10405	COG0316	Belongs to the HesB IscA family
CLI14_10410	COG0822	iron-sulfur transferase activity
CLI14_10420	COG1959	2 iron, 2 sulfur cluster binding
CLI14_10425	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CLI14_10430	COG0483	inositol monophosphate 1-phosphatase activity
CLI14_10435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLI14_10440	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLI14_10445	COG1862	Preprotein translocase
CLI14_10455	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CLI14_10460	COG0517	IMP dehydrogenase activity
CLI14_10470	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CLI14_10475	COG0583	DNA-binding transcription factor activity
CLI14_10480	COG0450	alkyl hydroperoxide reductase
CLI14_10485	COG3142	Participates in the control of copper homeostasis
CLI14_10490	COG0704	Plays a role in the regulation of phosphate uptake
CLI14_10495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLI14_10500	COG0581	inorganic phosphate transmembrane transporter activity
CLI14_10510	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CLI14_10515	COG0248	Ppx GppA phosphatase
CLI14_10525	COG5002	protein histidine kinase activity
CLI14_10530	COG0745	RESPONSE REGULATOR receiver
CLI14_10545	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLI14_10590	COG0542	response to heat
CLI14_10605	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLI14_10610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CLI14_10615	COG0077	Prephenate dehydratase
CLI14_10615	COG1605	Chorismate mutase
CLI14_10620	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CLI14_10625	COG5001	Diguanylate cyclase
CLI14_10630	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CLI14_10645	COG0488	(ABC) transporter
CLI14_10655	COG1605	Chorismate mutase
CLI14_10655	COG0287	Prephenate dehydrogenase
CLI14_10660	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLI14_10665	COG3275	phosphorelay sensor kinase activity
CLI14_10670	COG3279	Response regulator of the LytR AlgR family
CLI14_10675	COG1472	Belongs to the glycosyl hydrolase 3 family
CLI14_10680	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CLI14_10685	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CLI14_10700	COG1966	Carbon starvation protein
CLI14_10710	COG1047	Peptidyl-prolyl cis-trans
CLI14_10715	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CLI14_10725	COG0196	riboflavin kinase activity
CLI14_10730	COG0728	peptidoglycan biosynthetic process
CLI14_10740	COG0640	Transcriptional regulator
CLI14_10745	COG0583	DNA-binding transcription factor activity
CLI14_10750	COG1283	sodium-dependent phosphate transmembrane transporter activity
CLI14_10760	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CLI14_10790	COG2433	Pfam Transposase IS66
CLI14_10830	COG3550	peptidyl-serine autophosphorylation
CLI14_10845	COG3422	double-strand break repair
CLI14_10865	COG2433	Pfam Transposase IS66
CLI14_10875	COG2194	sulfuric ester hydrolase activity
CLI14_10880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CLI14_10905	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CLI14_10915	COG0730	response to heat
CLI14_10925	COG0494	nUDIX hydrolase
CLI14_10930	COG3066	DNA modification
CLI14_10935	COG0667	Aldo Keto reductase
CLI14_10945	COG2204	response regulator
CLI14_10950	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CLI14_10970	COG0513	Belongs to the DEAD box helicase family
CLI14_10995	COG3153	acetyltransferase
CLI14_11025	COG1846	Transcriptional regulator
CLI14_11045	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CLI14_11055	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CLI14_11060	COG0195	Participates in both transcription termination and antitermination
CLI14_11065	COG0779	Required for maturation of 30S ribosomal subunits
CLI14_11080	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CLI14_11085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLI14_11090	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CLI14_11095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLI14_11105	COG1534	Rna-binding protein
CLI14_11110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLI14_11120	COG2027	D-alanyl-D-alanine carboxypeptidase
CLI14_11125	COG2239	Acts as a magnesium transporter
CLI14_11135	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CLI14_11140	COG0739	heme binding
CLI14_11155	COG0316	Belongs to the HesB IscA family
CLI14_11160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CLI14_11165	COG0628	permease
CLI14_11190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLI14_11195	COG0444	Belongs to the ABC transporter superfamily
CLI14_11200	COG4608	Belongs to the ABC transporter superfamily
CLI14_11210	COG2971	BadF BadG BcrA BcrD
CLI14_11225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLI14_11240	COG1840	ABC-type Fe3 transport system, periplasmic component
CLI14_11245	COG0004	ammonium transporteR
CLI14_11260	COG3835	regulator
CLI14_11265	COG2610	gluconate transmembrane transporter activity
CLI14_11270	COG1929	Belongs to the glycerate kinase type-1 family
CLI14_11275	COG1049	propionate catabolic process, 2-methylcitrate cycle
CLI14_11280	COG1752	Esterase of the alpha-beta hydrolase superfamily
CLI14_11285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CLI14_11290	COG1643	Atp-dependent helicase
CLI14_11295	COG1489	DNA binding
CLI14_11300	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CLI14_11305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLI14_11315	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CLI14_11325	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CLI14_11335	COG0842	Transport permease protein
CLI14_11340	COG1131	(ABC) transporter
CLI14_11345	COG0659	secondary active sulfate transmembrane transporter activity
CLI14_11350	COG0288	reversible hydration of carbon dioxide
CLI14_11365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLI14_11370	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLI14_11375	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CLI14_11380	COG2186	Transcriptional regulator
CLI14_11385	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CLI14_11390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CLI14_11395	COG4974	Belongs to the 'phage' integrase family
CLI14_11400	COG0716	FMN binding
CLI14_11410	COG0157	Belongs to the NadC ModD family
CLI14_11425	COG1459	type II secretion system
CLI14_11435	COG0237	dephospho-CoA kinase activity
CLI14_11440	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CLI14_11445	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CLI14_11450	COG0335	large ribosomal subunit rRNA binding
CLI14_11470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CLI14_11475	COG4137	Cytochrome C assembly protein
CLI14_11480	COG4536	flavin adenine dinucleotide binding
CLI14_11495	COG0612	Peptidase, M16
CLI14_11500	COG1238	metal cluster binding
CLI14_11505	COG1063	alcohol dehydrogenase
CLI14_11510	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CLI14_11515	COG0511	ligase activity, forming carbon-carbon bonds
CLI14_11515	COG5016	pyruvate
CLI14_11520	COG3630	sodium ion export across plasma membrane
CLI14_11565	COG0527	aspartate kinase activity
CLI14_11570	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CLI14_11575	COG2137	regulation of response to DNA damage stimulus
CLI14_11580	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CLI14_11585	COG1546	Belongs to the CinA family
CLI14_11590	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CLI14_11595	COG4208	sulfate ABC transporter
CLI14_11605	COG4150	thiosulfate binding
CLI14_11615	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CLI14_11620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLI14_11625	COG4942	peptidase
CLI14_11625	COG1388	LysM domain
CLI14_11630	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CLI14_11635	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CLI14_11640	COG0585	pseudouridine synthase activity
CLI14_11645	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CLI14_11650	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CLI14_11655	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CLI14_11660	COG1968	undecaprenyl-diphosphatase activity
CLI14_11665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CLI14_11670	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CLI14_11695	COG1610	YqeY-like protein
CLI14_11700	COG0358	DNA primase activity
CLI14_11705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLI14_11720	COG3550	peptidyl-serine autophosphorylation
CLI14_11740	COG0210	DNA helicase
CLI14_11755	COG2433	Pfam Transposase IS66
CLI14_11900	COG4584	PFAM Integrase catalytic
CLI14_11905	COG1484	DNA-dependent DNA replication
CLI14_12060	COG3501	Rhs element vgr protein
CLI14_12080	COG4932	domain protein
CLI14_12080	COG5492	domain, Protein
CLI14_12090	COG1349	DNA-binding transcription factor activity
CLI14_12095	COG0469	pyruvate kinase activity
CLI14_12100	COG3706	GGDEF domain
CLI14_12120	COG0668	transmembrane transport
CLI14_12125	COG0191	fructose-bisphosphate aldolase activity
CLI14_12135	COG0126	phosphoglycerate kinase activity
CLI14_12140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CLI14_12145	COG4771	TonB-dependent receptor
CLI14_12150	COG0583	DNA-binding transcription factor activity
CLI14_12155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CLI14_12160	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CLI14_12165	COG3091	SprT-like family
CLI14_12170	COG2356	endonuclease I
CLI14_12175	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CLI14_12185	COG1678	Uncharacterized ACR, COG1678
CLI14_12190	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CLI14_12205	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CLI14_12210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLI14_12215	COG0762	integral membrane protein
CLI14_12220	COG1872	DUF167
CLI14_12235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLI14_12240	COG2066	Belongs to the glutaminase family
CLI14_12245	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CLI14_12260	COG0741	lytic transglycosylase activity
CLI14_12310	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CLI14_12315	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CLI14_12320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLI14_12325	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CLI14_12335	COG2967	ApaG domain
CLI14_12350	COG3610	response to peptide
CLI14_12355	COG2966	Psort location CytoplasmicMembrane, score
CLI14_12360	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CLI14_12365	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CLI14_12380	COG0142	geranyltranstransferase activity
CLI14_12385	COG0531	amino acid
CLI14_12415	COG0589	response to stress
CLI14_12445	COG3550	peptidyl-serine autophosphorylation
CLI14_12460	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CLI14_12470	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CLI14_12515	COG2235	arginine
CLI14_12520	COG0312	modulator of DNA gyrase
CLI14_12525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLI14_12530	COG3164	Protein of unknown function
CLI14_12535	COG1530	ribonuclease E activity
CLI14_12540	COG0424	maF-like protein
CLI14_12545	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CLI14_12550	COG1792	Involved in formation and maintenance of cell shape
CLI14_12555	COG1077	Cell shape determining protein MreB Mrl
CLI14_12600	COG1459	type II secretion system
CLI14_12605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLI14_12615	COG3409	Peptidoglycan-binding domain 1 protein
CLI14_12615	COG3267	Type II secretory pathway component ExeA
CLI14_12640	COG2200	EAL domain
CLI14_12640	COG2199	diguanylate cyclase activity
CLI14_12645	COG0629	single-stranded DNA binding
CLI14_12660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CLI14_12670	COG2239	Acts as a magnesium transporter
CLI14_12685	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CLI14_12690	COG0527	aspartate kinase activity
CLI14_12695	COG0646	methionine synthase
CLI14_12695	COG1410	methionine synthase
CLI14_12740	COG0175	sulfate reduction
CLI14_12745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLI14_12750	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CLI14_12770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLI14_12775	COG0735	belongs to the Fur family
CLI14_12785	COG0166	Belongs to the GPI family
CLI14_12790	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLI14_12795	COG0305	Participates in initiation and elongation during chromosome replication
CLI14_12805	COG0359	binds to the 23S rRNA
CLI14_12815	COG2965	DNA replication, synthesis of RNA primer
CLI14_12820	COG0360	Binds together with S18 to 16S ribosomal RNA
CLI14_12825	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLI14_12830	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLI14_12835	COG0049	tRNA binding
CLI14_12850	COG2923	Belongs to the DsrF TusC family
CLI14_12855	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CLI14_12860	COG2964	Protein conserved in bacteria
CLI14_12865	COG0545	Peptidyl-prolyl cis-trans isomerase
CLI14_12880	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CLI14_12885	COG0330	HflC and HflK could
CLI14_12890	COG0330	HflC and HflK could
CLI14_12895	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CLI14_12900	COG1923	regulation of RNA biosynthetic process
CLI14_12905	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CLI14_12910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CLI14_12920	COG0802	atpase or kinase
CLI14_12925	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CLI14_12975	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CLI14_12980	COG1162	GTPase activity
CLI14_12990	COG0490	domain, Protein
CLI14_12990	COG0471	metal ion transport
CLI14_13005	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CLI14_13010	COG4942	peptidase
CLI14_13030	COG2816	NAD+ diphosphatase activity
CLI14_13035	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CLI14_13040	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLI14_13045	COG0085	RNA polymerase activity
CLI14_13050	COG0222	ribosome binding
CLI14_13055	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CLI14_13060	COG0081	regulation of translation
CLI14_13070	COG0250	Participates in transcription elongation, termination and antitermination
CLI14_13075	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CLI14_13080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLI14_13105	COG1072	(Pantothenic acid kinase))
CLI14_13110	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CLI14_13110	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CLI14_13115	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CLI14_13125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLI14_13170	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CLI14_13180	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CLI14_13185	COG3118	belongs to the thioredoxin family
CLI14_13195	COG0248	Ppx GppA phosphatase
CLI14_13200	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CLI14_13205	COG0194	GDP metabolic process
CLI14_13210	COG1758	RNA polymerase activity
CLI14_13215	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLI14_13220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CLI14_13225	COG2233	PERMEase
CLI14_13235	COG0745	RESPONSE REGULATOR receiver
CLI14_13260	COG0583	DNA-binding transcription factor activity
CLI14_13280	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLI14_13285	COG2183	response to ionizing radiation
CLI14_13295	COG0596	Alpha beta hydrolase
CLI14_13300	COG1040	competence protein
CLI14_13305	COG0316	Belongs to the HesB IscA family
CLI14_13305	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CLI14_13310	COG0494	nUDIX hydrolase
CLI14_13315	COG1218	3'(2'),5'-bisphosphate nucleotidase
CLI14_13325	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CLI14_13330	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CLI14_13335	COG3156	type II secretion system protein K
CLI14_13340	COG4795	General secretion pathway protein
CLI14_13345	COG2165	general secretion pathway protein
CLI14_13350	COG2165	general secretion pathway protein
CLI14_13355	COG2165	general secretion pathway protein
CLI14_13360	COG1459	type II secretion system
CLI14_13365	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLI14_13375	COG3031	protein transport across the cell outer membrane
CLI14_13380	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CLI14_13385	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CLI14_13390	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CLI14_13400	COG0456	acetyltransferase
CLI14_13405	COG1490	D-aminoacyl-tRNA deacylase activity
CLI14_13420	COG0174	glutamine synthetase
CLI14_13430	COG3852	Histidine kinase
CLI14_13440	COG3300	MHYT domain
CLI14_13440	COG5001	Diguanylate cyclase
CLI14_13445	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CLI14_13520	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CLI14_13565	COG3550	peptidyl-serine autophosphorylation
CLI14_13605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CLI14_13640	COG3250	beta-galactosidase activity
CLI14_13665	COG0534	Mate efflux family protein
CLI14_13680	COG2937	Belongs to the GPAT DAPAT family
CLI14_13690	COG3161	chorismate lyase activity
CLI14_13695	COG1580	Controls the rotational direction of flagella during chemotaxis
CLI14_13700	COG0705	Rhomboid family
CLI14_13710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLI14_13715	COG2177	Part of the ABC transporter FtsEX involved in
CLI14_13720	COG2884	Cell division ATP-binding protein ftsE
CLI14_13725	COG0552	protein localization to endoplasmic reticulum
CLI14_13730	COG0742	ribosomal rna small subunit methyltransferase
CLI14_13775	COG2433	Pfam Transposase IS66
CLI14_13790	COG2095	MarC family integral membrane protein
CLI14_13820	COG0783	Belongs to the Dps family
CLI14_13825	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CLI14_13830	COG1280	lysine exporter protein (LysE YggA)
CLI14_13835	COG2267	carboxylic ester hydrolase activity
CLI14_13840	COG0561	phosphatase activity
CLI14_13855	COG1011	Hydrolase
CLI14_13860	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CLI14_13875	COG0019	diaminopimelate decarboxylase activity
CLI14_13890	COG3072	Adenylate cyclase
CLI14_13900	COG1587	Uroporphyrinogen-III synthase
CLI14_13905	COG2959	enzyme of heme biosynthesis
CLI14_13910	COG3071	HemY protein
CLI14_13945	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CLI14_13955	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLI14_13960	COG0408	coproporphyrinogen oxidase activity
CLI14_13965	COG0009	L-threonylcarbamoyladenylate synthase
CLI14_13970	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CLI14_13975	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CLI14_13980	COG0551	DNA topoisomerase type I activity
CLI14_13985	COG2922	Belongs to the Smg family
CLI14_13990	COG0758	DNA mediated transformation
CLI14_13995	COG1652	LysM domain
CLI14_14000	COG0242	peptide deformylase activity
CLI14_14005	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CLI14_14010	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CLI14_14010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLI14_14015	COG0569	domain protein
CLI14_14020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CLI14_14030	COG1272	protein, Hemolysin III
CLI14_14040	COG3084	Protein conserved in bacteria
CLI14_14055	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CLI14_14060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CLI14_14070	COG2433	Pfam Transposase IS66
CLI14_14090	COG2433	Pfam Transposase IS66
CLI14_14110	COG2433	Pfam Transposase IS66
CLI14_14180	COG0606	chelatase, subunit chli
CLI14_14190	COG3978	acetolactate synthase activity
CLI14_14195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLI14_14200	COG0129	dihydroxy-acid dehydratase activity
CLI14_14210	COG0604	alcohol dehydrogenase
CLI14_14235	COG2119	membrane
CLI14_14240	COG0752	glycyl-tRNA synthetase alpha subunit
CLI14_14250	COG3977	Valine--pyruvate aminotransferase
CLI14_14255	COG0071	Belongs to the small heat shock protein (HSP20) family
CLI14_14270	COG0187	DNA topoisomerase II activity
CLI14_14275	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CLI14_14280	COG0592	DNA-directed DNA polymerase activity
CLI14_14300	COG1126	abc transporter atp-binding protein
CLI14_14315	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CLI14_14320	COG0706	membrane insertase activity
CLI14_14330	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CLI14_14360	COG1444	tRNA N-acetyltransferase activity
CLI14_14370	COG0745	RESPONSE REGULATOR receiver
CLI14_14375	COG2198	Histidine kinase
CLI14_14375	COG0643	Histidine kinase
CLI14_14380	COG0835	chemotaxis
CLI14_14385	COG0835	chemotaxis
CLI14_14390	COG0840	transmembrane signaling receptor activity
CLI14_14395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CLI14_14400	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CLI14_14420	COG0745	RESPONSE REGULATOR receiver
CLI14_14420	COG3706	GGDEF domain
CLI14_14450	COG0259	pyridoxamine-phosphate oxidase activity
CLI14_14460	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CLI14_14515	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CLI14_14540	COG2909	trisaccharide binding
CLI14_14545	COG0058	SHG alpha-glucan phosphorylase activity
CLI14_14550	COG1640	4-alpha-glucanotransferase
CLI14_14555	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CLI14_14565	COG3501	Rhs element vgr protein
CLI14_14595	COG0583	DNA-binding transcription factor activity
CLI14_14605	COG0363	glucosamine-6-phosphate deaminase activity
CLI14_14610	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CLI14_14620	COG1067	ATP-dependent peptidase activity
CLI14_14630	COG2211	Major facilitator Superfamily
CLI14_14650	COG4580	involved in the transport of maltose and maltodextrins
CLI14_14655	COG1609	Transcriptional regulator
CLI14_14670	COG0395	ABC-type sugar transport system, permease component
CLI14_14675	COG3842	ATPase activity
CLI14_14680	COG1472	Belongs to the glycosyl hydrolase 3 family
CLI14_14685	COG1609	Transcriptional regulator
CLI14_14715	COG3568	Endonuclease Exonuclease Phosphatase
CLI14_14725	COG3122	Protein conserved in bacteria
CLI14_14730	COG1881	PFAM PEBP family protein
CLI14_14745	COG1304	FMN binding
CLI14_14750	COG1620	l-lactate permease
CLI14_14755	COG0583	DNA-binding transcription factor activity
CLI14_14780	COG3527	Alpha-acetolactate decarboxylase
CLI14_14790	COG0584	glycerophosphoryl diester phosphodiesterase
CLI14_14795	COG2271	Major facilitator Superfamily
CLI14_14800	COG3397	chitin binding
CLI14_14810	COG3047	cAMP biosynthetic process
CLI14_14830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLI14_14835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLI14_14845	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CLI14_14850	COG0573	inorganic phosphate transmembrane transporter activity
CLI14_14855	COG0581	inorganic phosphate transmembrane transporter activity
CLI14_14860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLI14_14880	COG0659	secondary active sulfate transmembrane transporter activity
CLI14_14890	COG0739	heme binding
CLI14_14895	COG5001	Diguanylate cyclase
CLI14_14900	COG0583	DNA-binding transcription factor activity
CLI14_14905	COG2814	Major facilitator Superfamily
CLI14_14925	COG0697	spore germination
CLI14_14935	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLI14_14955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLI14_14960	COG0765	amino acid transport
CLI14_14965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLI14_14970	COG0765	amino acid transport
CLI14_14980	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLI14_14990	COG3123	guanosine phosphorylase activity
CLI14_15000	COG1741	Belongs to the pirin family
CLI14_15010	COG5001	Diguanylate cyclase
CLI14_15045	COG3706	GGDEF domain
CLI14_15050	COG2315	Protein conserved in bacteria
CLI14_15055	COG0784	Response regulator, receiver
CLI14_15055	COG0835	chemotaxis
CLI14_15060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLI14_15070	COG3842	ATPase activity
CLI14_15080	COG1175	transmembrane transport
CLI14_15110	COG1349	DNA-binding transcription factor activity
CLI14_15115	COG3706	GGDEF domain
CLI14_15140	COG2197	response regulator
CLI14_15170	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CLI14_15175	COG2354	Protein conserved in bacteria
CLI14_15180	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLI14_15190	COG3217	Mosc domain protein beta barrel domain protein
CLI14_15190	COG0633	Ferredoxin
CLI14_15195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLI14_15210	COG3604	Transcriptional regulator
CLI14_15220	COG4681	YaeQ
CLI14_15225	COG1278	Cold shock
CLI14_15250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLI14_15255	COG0516	GMP reductase activity
CLI14_15270	COG0589	response to stress
CLI14_15275	COG0659	secondary active sulfate transmembrane transporter activity
CLI14_15285	COG0798	PFAM Bile acid sodium symporter
CLI14_15290	COG0640	Transcriptional regulator
CLI14_15295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CLI14_15315	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CLI14_15330	COG2271	Major facilitator Superfamily
CLI14_15335	COG3851	Histidine kinase
CLI14_15340	COG2197	response regulator
CLI14_15355	COG0346	lactoylglutathione lyase activity
CLI14_15365	COG0156	8-amino-7-oxononanoate synthase activity
CLI14_15370	COG1063	alcohol dehydrogenase
CLI14_15375	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CLI14_15385	COG1368	sulfuric ester hydrolase activity
CLI14_15390	COG3530	Putative quorum-sensing-regulated virulence factor
CLI14_15395	COG1403	HNH endonuclease
CLI14_15405	COG3706	GGDEF domain
CLI14_15420	COG2304	oxidoreductase activity
CLI14_15440	COG0714	Associated with various cellular activities
CLI14_15460	COG0366	Alpha amylase catalytic
CLI14_15500	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CLI14_15510	COG0456	acetyltransferase
CLI14_15515	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLI14_15520	COG0662	Cupin 2, conserved barrel domain protein
CLI14_15525	COG0527	aspartate kinase activity
CLI14_15545	COG2113	Glycine betaine
CLI14_15550	COG4176	ABC-type proline glycine betaine transport system permease component
CLI14_15565	COG1166	arginine decarboxylase activity
CLI14_15570	COG0010	Belongs to the arginase family
CLI14_15590	COG3300	MHYT domain
CLI14_15590	COG5001	Diguanylate cyclase
CLI14_15595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLI14_15640	COG0484	heat shock protein binding
CLI14_15650	COG5001	Diguanylate cyclase
CLI14_15650	COG1716	ATPase activity
CLI14_15655	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CLI14_15665	COG4181	ATPase activity
CLI14_15670	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CLI14_15680	COG1984	allophanate hydrolase subunit 2
CLI14_15690	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CLI14_15695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CLI14_15705	COG0814	amino acid
CLI14_15710	COG0513	Belongs to the DEAD box helicase family
CLI14_15720	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CLI14_15735	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CLI14_15750	COG4175	Glycine betaine
CLI14_15750	COG0517	IMP dehydrogenase activity
CLI14_15755	COG4176	ABC-type proline glycine betaine transport system permease component
CLI14_15785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLI14_15790	COG2146	nitrite reductase [NAD(P)H] activity
CLI14_15805	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLI14_15825	COG3118	belongs to the thioredoxin family
CLI14_15830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLI14_15835	COG0247	lactate metabolic process
CLI14_15840	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CLI14_15845	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CLI14_15850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CLI14_15855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CLI14_15880	COG2827	Endonuclease containing a URI domain
CLI14_15895	COG5002	protein histidine kinase activity
CLI14_15895	COG0784	Response regulator, receiver
CLI14_15925	COG1289	transmembrane transporter activity
CLI14_15930	COG0210	DNA helicase
CLI14_15935	COG1803	Methylglyoxal synthase
CLI14_15940	COG1879	ABC-type sugar transport system periplasmic component
CLI14_15945	COG0784	Response regulator, receiver
CLI14_15945	COG2198	Histidine kinase
CLI14_15945	COG2205	protein histidine kinase activity
CLI14_15950	COG0469	pyruvate kinase activity
CLI14_15955	COG2271	Major facilitator Superfamily
CLI14_15965	COG1840	ABC-type Fe3 transport system, periplasmic component
CLI14_15980	COG1979	alcohol dehydrogenase
CLI14_15985	COG2207	Transcriptional regulator
CLI14_15995	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CLI14_16000	COG3447	MASE1 domain protein
CLI14_16000	COG5001	Diguanylate cyclase
CLI14_16000	COG5002	protein histidine kinase activity
CLI14_16010	COG3111	PFAM Bacterial OB fold (BOF) protein
CLI14_16015	COG1492	cobalamin metabolic process
CLI14_16020	COG0725	ABC transporter, periplasmic molybdate-binding protein
CLI14_16025	COG4149	molybdate abc transporter
CLI14_16030	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CLI14_16040	COG3706	GGDEF domain
CLI14_16040	COG2203	Gaf domain
CLI14_16040	COG4251	negative regulation of phosphorylation
CLI14_16040	COG5001	Diguanylate cyclase
CLI14_16055	COG3437	response regulator, receiver
CLI14_16065	COG3852	Histidine kinase
CLI14_16070	COG4191	Histidine kinase
CLI14_16075	COG5001	Diguanylate cyclase
CLI14_16075	COG3300	MHYT domain
CLI14_16095	COG0640	Transcriptional regulator
CLI14_16120	COG3706	GGDEF domain
CLI14_16125	COG1328	CTP reductase activity
CLI14_16130	COG0602	queuosine metabolic process
CLI14_16140	COG0189	ligase activity
CLI14_16140	COG4067	protein conserved in archaea
CLI14_16155	COG4166	transmembrane transport
CLI14_16160	COG4174	ABC transporter (Permease)
CLI14_16165	COG4239	(ABC) transporter, permease
CLI14_16170	COG4172	Belongs to the ABC transporter superfamily
CLI14_16175	COG4251	negative regulation of phosphorylation
CLI14_16175	COG5001	Diguanylate cyclase
CLI14_16175	COG2203	Gaf domain
CLI14_16175	COG3706	GGDEF domain
CLI14_16185	COG3038	cytochrome b561
CLI14_16190	COG2353	YceI-like domain
CLI14_16195	COG0840	transmembrane signaling receptor activity
CLI14_16200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLI14_16205	COG0545	Peptidyl-prolyl cis-trans isomerase
CLI14_16220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CLI14_16240	COG2897	thiosulfate sulfurtransferase activity
CLI14_16245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CLI14_16250	COG0303	'Molybdopterin
CLI14_16255	COG0302	gtp cyclohydrolase
CLI14_16260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLI14_16260	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLI14_16265	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CLI14_16270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLI14_16275	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CLI14_16285	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CLI14_16290	COG1011	Hydrolase
CLI14_16295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLI14_16300	COG2188	Transcriptional regulator
CLI14_16320	COG2116	formate transmembrane transporter activity
CLI14_16325	COG0583	DNA-binding transcription factor activity
CLI14_16335	COG3593	DNA synthesis involved in DNA repair
CLI14_16340	COG0737	Belongs to the 5'-nucleotidase family
CLI14_16350	COG2433	Pfam Transposase IS66
CLI14_16390	COG2433	Pfam Transposase IS66
CLI14_16425	COG2433	Pfam Transposase IS66
CLI14_16655	COG3040	lipid binding
CLI14_16725	COG2433	Pfam Transposase IS66
CLI14_16755	COG0724	RNA recognition motif
CLI14_16885	COG0023	Translation Initiation Factor
CLI14_16900	COG1181	Belongs to the D-alanine--D-alanine ligase family
CLI14_16910	COG0045	succinate-CoA ligase (ADP-forming) activity
CLI14_16910	COG1042	CoA-binding domain protein
CLI14_16910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLI14_16915	COG0583	DNA-binding transcription factor activity
CLI14_16935	COG2433	Pfam Transposase IS66
CLI14_17035	COG2433	Pfam Transposase IS66
CLI14_17205	COG2433	Pfam Transposase IS66
CLI14_17220	COG0500	methyltransferase
CLI14_17240	COG2433	Pfam Transposase IS66
CLI14_17265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CLI14_17270	COG0513	Belongs to the DEAD box helicase family
CLI14_17275	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CLI14_17285	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CLI14_17310	COG3069	C4-dicarboxylate transmembrane transporter activity
CLI14_17315	COG2197	response regulator
CLI14_17320	COG3850	Histidine kinase
CLI14_17325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLI14_17335	COG0243	molybdopterin cofactor binding
CLI14_17345	COG3005	denitrification pathway
CLI14_17355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLI14_17360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLI14_17385	COG3833	ABC-type maltose transport systems, permease component
CLI14_17390	COG1175	transmembrane transport
CLI14_17395	COG2182	Extracellular solute-binding protein
CLI14_17405	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLI14_17415	COG3842	ATPase activity
CLI14_17430	COG3730	PTS system glucitol sorbitol-specific
CLI14_17435	COG1349	DNA-binding transcription factor activity
CLI14_17440	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI14_17445	COG1028	Short-chain dehydrogenase reductase Sdr
CLI14_17460	COG3730	PTS system glucitol sorbitol-specific
CLI14_17490	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CLI14_17505	COG1136	(ABC) transporter
CLI14_17505	COG0577	efflux transmembrane transporter activity
CLI14_17515	COG1136	(ABC) transporter
CLI14_17520	COG0523	cobalamin synthesis protein
CLI14_17535	COG0156	8-amino-7-oxononanoate synthase activity
CLI14_17540	COG0784	Response regulator, receiver
CLI14_17540	COG2205	protein histidine kinase activity
CLI14_17545	COG0419	ATPase involved in DNA repair
CLI14_17550	COG0420	3'-5' exonuclease activity
CLI14_17555	COG1609	Transcriptional regulator
CLI14_17560	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI14_17560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI14_17565	COG1105	Belongs to the carbohydrate kinase PfkB family
CLI14_17570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLI14_17570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLI14_17570	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CLI14_17585	COG0612	Peptidase, M16
CLI14_17600	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CLI14_17610	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CLI14_17635	COG1566	PFAM secretion protein HlyD family protein
CLI14_17660	COG0656	L-ascorbic acid biosynthetic process
CLI14_17665	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLI14_17675	COG0861	Integral membrane protein TerC family
CLI14_17685	COG2226	methyltransferase
CLI14_17695	COG1162	GTPase activity
CLI14_17700	COG2433	Pfam Transposase IS66
CLI14_17735	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CLI14_17745	COG4604	ABC transporter, ATP-binding protein
CLI14_17750	COG4605	iron ion homeostasis
CLI14_17755	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLI14_17760	COG4607	ABC-type enterochelin transport system periplasmic component
CLI14_17785	COG4412	M6 family metalloprotease domain protein
CLI14_17785	COG3291	Pkd domain containing protein
CLI14_17790	COG5380	lipid catabolic process
CLI14_17795	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CLI14_17805	COG3240	lipase activity
CLI14_17820	COG0443	Heat shock 70 kDa protein
CLI14_17830	COG2814	Major facilitator Superfamily
CLI14_17840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLI14_17840	COG4191	Histidine kinase
CLI14_17845	COG0784	Response regulator, receiver
CLI14_17845	COG3437	response regulator, receiver
CLI14_17850	COG2207	Transcriptional regulator
CLI14_17855	COG0534	Mate efflux family protein
CLI14_17860	COG0840	transmembrane signaling receptor activity
CLI14_17870	COG3186	Phenylalanine-4-hydroxylase
CLI14_17875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLI14_17880	COG0583	DNA-binding transcription factor activity
CLI14_17890	COG0583	DNA-binding transcription factor activity
CLI14_17905	COG0110	maltose O-acetyltransferase activity
CLI14_17910	COG1765	OsmC-like protein
CLI14_17915	COG0673	inositol 2-dehydrogenase activity
CLI14_17935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLI14_17950	COG2205	protein histidine kinase activity
CLI14_17950	COG5002	protein histidine kinase activity
CLI14_17950	COG0784	Response regulator, receiver
CLI14_17975	COG0531	amino acid
CLI14_17985	COG4999	Histidine kinase
CLI14_17985	COG3850	Histidine kinase
CLI14_17985	COG2205	protein histidine kinase activity
CLI14_17985	COG3437	response regulator, receiver
CLI14_17990	COG3437	response regulator, receiver
CLI14_18000	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CLI14_18010	COG3706	GGDEF domain
CLI14_18010	COG5001	Diguanylate cyclase
CLI14_18010	COG4251	negative regulation of phosphorylation
CLI14_18010	COG2203	Gaf domain
CLI14_18015	COG3279	Response regulator of the LytR AlgR family
CLI14_18020	COG2972	Histidine kinase
CLI14_18020	COG0745	RESPONSE REGULATOR receiver
CLI14_18035	COG4591	ABC-type transport system involved in lipoprotein release permease component
CLI14_18040	COG0577	efflux transmembrane transporter activity
CLI14_18040	COG1136	(ABC) transporter
CLI14_18050	COG4989	oxidoreductase activity
CLI14_18055	COG0366	Alpha amylase catalytic
CLI14_18065	COG2267	carboxylic ester hydrolase activity
CLI14_18070	COG2188	Transcriptional regulator
CLI14_18080	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CLI14_18095	COG3457	Alanine racemase
CLI14_18100	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CLI14_18130	COG0513	Belongs to the DEAD box helicase family
CLI14_18140	COG1376	ErfK ybiS ycfS ynhG family protein
CLI14_18140	COG1388	LysM domain
CLI14_18145	COG0415	Belongs to the DNA photolyase family
CLI14_18150	COG0789	Transcriptional regulator
CLI14_18155	COG3272	Protein of unknown function (DUF1722)
CLI14_18160	COG0813	purine-nucleoside phosphorylase activity
CLI14_18175	COG3706	GGDEF domain
CLI14_18185	COG1566	PFAM secretion protein HlyD family protein
CLI14_18210	COG0786	glutamate:sodium symporter activity
CLI14_18230	COG1999	signal sequence binding
CLI14_18240	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CLI14_18310	COG0561	phosphatase activity
CLI14_18315	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CLI14_18320	COG3623	hexulose-6-phosphate isomerase
CLI14_18340	COG1132	(ABC) transporter
CLI14_18345	COG4399	Belongs to the UPF0754 family
CLI14_18350	COG0671	phosphoesterase, PA-phosphatase related
CLI14_18390	COG1131	(ABC) transporter
CLI14_18395	COG2188	Transcriptional regulator
CLI14_18405	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CLI14_18465	COG3501	Rhs element vgr protein
CLI14_18555	COG0564	pseudouridine synthase activity
CLI14_18565	COG0745	RESPONSE REGULATOR receiver
CLI14_18580	COG1309	transcriptional regulator
CLI14_18585	COG2130	NADP-dependent
CLI14_18595	COG1328	CTP reductase activity
CLI14_18600	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CLI14_18610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLI14_18615	COG0251	oxidation-reduction process
CLI14_18620	COG0513	Belongs to the DEAD box helicase family
CLI14_18640	COG1176	ABC-type spermidine putrescine transport system, permease component I
CLI14_18650	COG3842	ATPase activity
CLI14_18665	COG1131	(ABC) transporter
CLI14_18670	COG0842	Transport permease protein
CLI14_18675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLI14_18680	COG3046	protein related to deoxyribodipyrimidine photolyase
CLI14_18685	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CLI14_18695	COG1846	Transcriptional regulator
CLI14_18720	COG2259	Doxx family
CLI14_18725	COG1301	dicarboxylic acid transport
CLI14_18730	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CLI14_18740	COG3722	fumarate hydratase activity
CLI14_18745	COG0246	Mannitol dehydrogenase
CLI14_18750	COG2213	PTS system mannitol-specific
CLI14_18750	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI14_18755	COG0739	heme binding
CLI14_18765	COG0363	glucosamine-6-phosphate deaminase activity
CLI14_18800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CLI14_18815	COG3304	Inner membrane component domain
CLI14_18825	COG2910	NAD(P)H-binding
CLI14_18830	COG0583	DNA-binding transcription factor activity
CLI14_18870	COG0814	amino acid
CLI14_18875	COG2084	Dehydrogenase
CLI14_18965	COG4604	ABC transporter, ATP-binding protein
CLI14_18970	COG3433	isochorismatase activity
CLI14_18970	COG1535	isochorismatase
CLI14_18975	COG1021	2,3-dihydroxybenzoate-AMP ligase
CLI14_18980	COG1169	isochorismate synthase
CLI14_18995	COG2433	Pfam Transposase IS66
CLI14_19060	COG1028	Short-chain dehydrogenase reductase Sdr
CLI14_19075	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLI14_19080	COG4605	iron ion homeostasis
CLI14_19085	COG4607	ABC-type enterochelin transport system periplasmic component
CLI14_19090	COG4774	siderophore transport
CLI14_19095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI14_19100	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CLI14_19125	COG0076	glutamate decarboxylase activity
CLI14_19130	COG1122	ATPase activity
CLI14_19150	COG2433	Pfam Transposase IS66
CLI14_19175	COG3657	addiction module killer protein
CLI14_19200	COG1192	Involved in chromosome partitioning