locus-tag	class	description
CEQ50_00005	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEQ50_00020	COG1395	domain, Protein
CEQ50_00095	COG4974	Belongs to the 'phage' integrase family
CEQ50_00105	COG0706	membrane insertase activity
CEQ50_00110	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CEQ50_00125	COG1126	abc transporter atp-binding protein
CEQ50_00145	COG0592	DNA-directed DNA polymerase activity
CEQ50_00150	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEQ50_00155	COG0187	DNA topoisomerase II activity
CEQ50_00170	COG0071	Belongs to the small heat shock protein (HSP20) family
CEQ50_00175	COG3977	Valine--pyruvate aminotransferase
CEQ50_00185	COG0752	glycyl-tRNA synthetase alpha subunit
CEQ50_00190	COG2119	membrane
CEQ50_00215	COG0604	alcohol dehydrogenase
CEQ50_00225	COG0129	dihydroxy-acid dehydratase activity
CEQ50_00230	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEQ50_00235	COG3978	acetolactate synthase activity
CEQ50_00245	COG0606	chelatase, subunit chli
CEQ50_00285	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CEQ50_00290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEQ50_00295	COG4107	phosphonate C-P lyase system protein PhnK
CEQ50_00300	COG3627	carbon phosphorus lyase activity
CEQ50_00305	COG3626	phosphonate metabolism
CEQ50_00340	COG0583	DNA-binding transcription factor activity
CEQ50_00345	COG0606	chelatase, subunit chli
CEQ50_00355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEQ50_00360	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CEQ50_00375	COG3084	Protein conserved in bacteria
CEQ50_00385	COG1272	protein, Hemolysin III
CEQ50_00395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEQ50_00400	COG0569	domain protein
CEQ50_00405	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEQ50_00405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEQ50_00410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEQ50_00415	COG0242	peptide deformylase activity
CEQ50_00420	COG1652	LysM domain
CEQ50_00425	COG0758	DNA mediated transformation
CEQ50_00430	COG2922	Belongs to the Smg family
CEQ50_00435	COG0551	DNA topoisomerase type I activity
CEQ50_00440	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CEQ50_00445	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CEQ50_00450	COG0009	L-threonylcarbamoyladenylate synthase
CEQ50_00455	COG0408	coproporphyrinogen oxidase activity
CEQ50_00460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CEQ50_00470	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CEQ50_00505	COG3071	HemY protein
CEQ50_00510	COG2959	enzyme of heme biosynthesis
CEQ50_00515	COG1587	Uroporphyrinogen-III synthase
CEQ50_00525	COG3072	Adenylate cyclase
CEQ50_00540	COG0019	diaminopimelate decarboxylase activity
CEQ50_00555	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CEQ50_00560	COG1011	Hydrolase
CEQ50_00575	COG0561	phosphatase activity
CEQ50_00580	COG2267	carboxylic ester hydrolase activity
CEQ50_00585	COG1280	lysine exporter protein (LysE YggA)
CEQ50_00590	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CEQ50_00595	COG0783	Belongs to the Dps family
CEQ50_00625	COG2095	MarC family integral membrane protein
CEQ50_00635	COG0742	ribosomal rna small subunit methyltransferase
CEQ50_00640	COG0552	protein localization to endoplasmic reticulum
CEQ50_00645	COG2884	Cell division ATP-binding protein ftsE
CEQ50_00650	COG2177	Part of the ABC transporter FtsEX involved in
CEQ50_00655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEQ50_00665	COG0705	Rhomboid family
CEQ50_00670	COG1580	Controls the rotational direction of flagella during chemotaxis
CEQ50_00675	COG3161	chorismate lyase activity
CEQ50_00685	COG2937	Belongs to the GPAT DAPAT family
CEQ50_00700	COG0534	Mate efflux family protein
CEQ50_00720	COG3250	beta-galactosidase activity
CEQ50_00750	COG0848	biopolymer transport protein
CEQ50_00755	COG0811	peptide transport
CEQ50_00760	COG0811	peptide transport
CEQ50_00770	COG4771	TonB-dependent receptor
CEQ50_00775	COG4178	(ABC) transporter
CEQ50_00780	COG0612	Peptidase, M16
CEQ50_00800	COG2003	Belongs to the UPF0758 family
CEQ50_00815	COG3339	Conserved Protein
CEQ50_00895	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CEQ50_00905	COG3344	reverse transcriptase
CEQ50_00935	COG2433	Pfam Transposase IS66
CEQ50_00945	COG2194	sulfuric ester hydrolase activity
CEQ50_00950	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEQ50_00970	COG2433	Pfam Transposase IS66
CEQ50_00990	COG3550	peptidyl-serine autophosphorylation
CEQ50_01015	COG4206	TonB-dependent receptor
CEQ50_01025	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CEQ50_01060	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CEQ50_01065	COG3300	MHYT domain
CEQ50_01065	COG5001	Diguanylate cyclase
CEQ50_01075	COG3852	Histidine kinase
CEQ50_01085	COG0174	glutamine synthetase
CEQ50_01100	COG1490	D-aminoacyl-tRNA deacylase activity
CEQ50_01105	COG0456	acetyltransferase
CEQ50_01115	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CEQ50_01120	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CEQ50_01125	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CEQ50_01130	COG3031	protein transport across the cell outer membrane
CEQ50_01140	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEQ50_01145	COG1459	type II secretion system
CEQ50_01150	COG2165	general secretion pathway protein
CEQ50_01155	COG2165	general secretion pathway protein
CEQ50_01160	COG2165	general secretion pathway protein
CEQ50_01165	COG4795	General secretion pathway protein
CEQ50_01170	COG3156	type II secretion system protein K
CEQ50_01175	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CEQ50_01180	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CEQ50_01190	COG1218	3'(2'),5'-bisphosphate nucleotidase
CEQ50_01195	COG0494	nUDIX hydrolase
CEQ50_01200	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CEQ50_01200	COG0316	Belongs to the HesB IscA family
CEQ50_01205	COG1040	competence protein
CEQ50_01210	COG0596	Alpha beta hydrolase
CEQ50_01220	COG2183	response to ionizing radiation
CEQ50_01225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEQ50_01245	COG0583	DNA-binding transcription factor activity
CEQ50_01270	COG0745	RESPONSE REGULATOR receiver
CEQ50_01280	COG2233	PERMEase
CEQ50_01285	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CEQ50_01290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEQ50_01295	COG1758	RNA polymerase activity
CEQ50_01300	COG0194	GDP metabolic process
CEQ50_01305	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CEQ50_01315	COG1943	Transposase
CEQ50_01320	COG0248	Ppx GppA phosphatase
CEQ50_01330	COG3118	belongs to the thioredoxin family
CEQ50_01335	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CEQ50_01345	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CEQ50_01405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEQ50_01415	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEQ50_01420	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CEQ50_01420	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CEQ50_01425	COG1072	(Pantothenic acid kinase))
CEQ50_01450	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEQ50_01455	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEQ50_01460	COG0250	Participates in transcription elongation, termination and antitermination
CEQ50_01470	COG0081	regulation of translation
CEQ50_01475	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CEQ50_01480	COG0222	ribosome binding
CEQ50_01485	COG0085	RNA polymerase activity
CEQ50_01490	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CEQ50_01495	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CEQ50_01500	COG2816	NAD+ diphosphatase activity
CEQ50_01520	COG4942	peptidase
CEQ50_01525	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CEQ50_01540	COG0490	domain, Protein
CEQ50_01540	COG0471	metal ion transport
CEQ50_01550	COG1162	GTPase activity
CEQ50_01555	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CEQ50_01605	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CEQ50_01610	COG0802	atpase or kinase
CEQ50_01620	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CEQ50_01630	COG1923	regulation of RNA biosynthetic process
CEQ50_01635	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEQ50_01640	COG0330	HflC and HflK could
CEQ50_01645	COG0330	HflC and HflK could
CEQ50_01650	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CEQ50_01665	COG0545	Peptidyl-prolyl cis-trans isomerase
CEQ50_01670	COG2964	Protein conserved in bacteria
CEQ50_01675	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CEQ50_01680	COG2923	Belongs to the DsrF TusC family
CEQ50_01695	COG0049	tRNA binding
CEQ50_01700	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEQ50_01705	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEQ50_01710	COG0360	Binds together with S18 to 16S ribosomal RNA
CEQ50_01715	COG2965	DNA replication, synthesis of RNA primer
CEQ50_01725	COG0359	binds to the 23S rRNA
CEQ50_01735	COG0305	Participates in initiation and elongation during chromosome replication
CEQ50_01740	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEQ50_01745	COG0166	Belongs to the GPI family
CEQ50_01755	COG0735	belongs to the Fur family
CEQ50_01760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEQ50_01780	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEQ50_01785	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEQ50_01790	COG0175	sulfate reduction
CEQ50_01875	COG0646	methionine synthase
CEQ50_01875	COG1410	methionine synthase
CEQ50_01880	COG0527	aspartate kinase activity
CEQ50_01885	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CEQ50_01900	COG2239	Acts as a magnesium transporter
CEQ50_01910	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEQ50_01950	COG2433	Pfam Transposase IS66
CEQ50_01965	COG2433	Pfam Transposase IS66
CEQ50_02020	COG0629	single-stranded DNA binding
CEQ50_02025	COG2199	diguanylate cyclase activity
CEQ50_02025	COG2200	EAL domain
CEQ50_02050	COG3409	Peptidoglycan-binding domain 1 protein
CEQ50_02050	COG3267	Type II secretory pathway component ExeA
CEQ50_02060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEQ50_02065	COG1459	type II secretion system
CEQ50_02110	COG1077	Cell shape determining protein MreB Mrl
CEQ50_02115	COG1792	Involved in formation and maintenance of cell shape
CEQ50_02120	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CEQ50_02125	COG0424	maF-like protein
CEQ50_02130	COG1530	ribonuclease E activity
CEQ50_02135	COG3164	Protein of unknown function
CEQ50_02140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEQ50_02145	COG0312	modulator of DNA gyrase
CEQ50_02160	COG2433	Pfam Transposase IS66
CEQ50_02165	COG1943	Transposase
CEQ50_02175	COG2235	arginine
CEQ50_02195	COG0589	response to stress
CEQ50_02225	COG0531	amino acid
CEQ50_02230	COG0142	geranyltranstransferase activity
CEQ50_02245	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CEQ50_02250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEQ50_02255	COG2966	Psort location CytoplasmicMembrane, score
CEQ50_02260	COG3610	response to peptide
CEQ50_02275	COG2967	ApaG domain
CEQ50_02285	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CEQ50_02290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEQ50_02295	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CEQ50_02300	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CEQ50_02350	COG0741	lytic transglycosylase activity
CEQ50_02365	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CEQ50_02370	COG2066	Belongs to the glutaminase family
CEQ50_02375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEQ50_02390	COG1872	DUF167
CEQ50_02395	COG0762	integral membrane protein
CEQ50_02400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CEQ50_02405	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CEQ50_02420	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CEQ50_02425	COG1678	Uncharacterized ACR, COG1678
CEQ50_02435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEQ50_02440	COG2356	endonuclease I
CEQ50_02445	COG3091	SprT-like family
CEQ50_02450	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CEQ50_02455	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEQ50_02460	COG0583	DNA-binding transcription factor activity
CEQ50_02465	COG4771	TonB-dependent receptor
CEQ50_02470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEQ50_02475	COG0126	phosphoglycerate kinase activity
CEQ50_02485	COG0191	fructose-bisphosphate aldolase activity
CEQ50_02490	COG0668	transmembrane transport
CEQ50_02510	COG3706	GGDEF domain
CEQ50_02515	COG0469	pyruvate kinase activity
CEQ50_02520	COG1349	DNA-binding transcription factor activity
CEQ50_02545	COG3501	Rhs element vgr protein
CEQ50_02580	COG2378	regulation of single-species biofilm formation
CEQ50_02660	COG2433	Pfam Transposase IS66
CEQ50_02705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEQ50_02715	COG1610	YqeY-like protein
CEQ50_02735	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CEQ50_02740	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CEQ50_02745	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEQ50_02750	COG1968	undecaprenyl-diphosphatase activity
CEQ50_02755	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CEQ50_02760	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CEQ50_02765	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CEQ50_02770	COG0585	pseudouridine synthase activity
CEQ50_02775	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CEQ50_02780	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CEQ50_02785	COG4942	peptidase
CEQ50_02785	COG1388	LysM domain
CEQ50_02790	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEQ50_02795	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEQ50_02815	COG4208	sulfate ABC transporter
CEQ50_02820	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CEQ50_02825	COG1546	Belongs to the CinA family
CEQ50_02830	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CEQ50_02835	COG2137	regulation of response to DNA damage stimulus
CEQ50_02840	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEQ50_02845	COG0527	aspartate kinase activity
CEQ50_02900	COG0511	ligase activity, forming carbon-carbon bonds
CEQ50_02900	COG5016	pyruvate
CEQ50_02905	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CEQ50_02910	COG1063	alcohol dehydrogenase
CEQ50_02915	COG1238	metal cluster binding
CEQ50_02920	COG0612	Peptidase, M16
CEQ50_02935	COG4536	flavin adenine dinucleotide binding
CEQ50_02940	COG4137	Cytochrome C assembly protein
CEQ50_02945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEQ50_02965	COG0335	large ribosomal subunit rRNA binding
CEQ50_02970	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CEQ50_02975	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CEQ50_02980	COG0237	dephospho-CoA kinase activity
CEQ50_02990	COG1459	type II secretion system
CEQ50_02995	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEQ50_03005	COG0157	Belongs to the NadC ModD family
CEQ50_03015	COG0716	FMN binding
CEQ50_03020	COG4974	Belongs to the 'phage' integrase family
CEQ50_03025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEQ50_03030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CEQ50_03035	COG2186	Transcriptional regulator
CEQ50_03040	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CEQ50_03045	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEQ50_03050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEQ50_03065	COG0288	reversible hydration of carbon dioxide
CEQ50_03070	COG0659	secondary active sulfate transmembrane transporter activity
CEQ50_03075	COG1131	(ABC) transporter
CEQ50_03080	COG0842	Transport permease protein
CEQ50_03090	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CEQ50_03100	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEQ50_03110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEQ50_03115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CEQ50_03120	COG1489	DNA binding
CEQ50_03125	COG1643	Atp-dependent helicase
CEQ50_03130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEQ50_03135	COG1752	Esterase of the alpha-beta hydrolase superfamily
CEQ50_03140	COG1049	propionate catabolic process, 2-methylcitrate cycle
CEQ50_03145	COG1929	Belongs to the glycerate kinase type-1 family
CEQ50_03150	COG2610	gluconate transmembrane transporter activity
CEQ50_03155	COG3835	regulator
CEQ50_03170	COG0004	ammonium transporteR
CEQ50_03175	COG1840	ABC-type Fe3 transport system, periplasmic component
CEQ50_03185	COG3842	ATPase activity
CEQ50_03190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEQ50_03205	COG2971	BadF BadG BcrA BcrD
CEQ50_03215	COG4608	Belongs to the ABC transporter superfamily
CEQ50_03220	COG0444	Belongs to the ABC transporter superfamily
CEQ50_03225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEQ50_03250	COG0628	permease
CEQ50_03255	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEQ50_03260	COG0316	Belongs to the HesB IscA family
CEQ50_03275	COG0739	heme binding
CEQ50_03280	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CEQ50_03290	COG2239	Acts as a magnesium transporter
CEQ50_03295	COG2027	D-alanyl-D-alanine carboxypeptidase
CEQ50_03300	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CEQ50_03305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEQ50_03310	COG1534	Rna-binding protein
CEQ50_03320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEQ50_03325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CEQ50_03330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEQ50_03335	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEQ50_03350	COG0779	Required for maturation of 30S ribosomal subunits
CEQ50_03355	COG0195	Participates in both transcription termination and antitermination
CEQ50_03370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CEQ50_03390	COG1846	Transcriptional regulator
CEQ50_03420	COG3153	acetyltransferase
CEQ50_03445	COG0513	Belongs to the DEAD box helicase family
CEQ50_03465	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CEQ50_03475	COG1943	Transposase
CEQ50_03480	COG2204	response regulator
CEQ50_03490	COG0667	Aldo Keto reductase
CEQ50_03495	COG3066	DNA modification
CEQ50_03500	COG0494	nUDIX hydrolase
CEQ50_03505	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CEQ50_03510	COG0730	response to heat
CEQ50_03525	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEQ50_03540	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CEQ50_03545	COG0732	type I restriction modification DNA specificity domain
CEQ50_03550	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CEQ50_03565	COG3550	peptidyl-serine autophosphorylation
CEQ50_03590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEQ50_03610	COG2433	Pfam Transposase IS66
CEQ50_03640	COG2433	Pfam Transposase IS66
CEQ50_03660	COG2433	Pfam Transposase IS66
CEQ50_03675	COG1283	sodium-dependent phosphate transmembrane transporter activity
CEQ50_03680	COG0583	DNA-binding transcription factor activity
CEQ50_03685	COG0640	Transcriptional regulator
CEQ50_03695	COG0728	peptidoglycan biosynthetic process
CEQ50_03700	COG0196	riboflavin kinase activity
CEQ50_03710	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CEQ50_03715	COG1047	Peptidyl-prolyl cis-trans
CEQ50_03725	COG1966	Carbon starvation protein
CEQ50_03735	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEQ50_03740	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CEQ50_03745	COG1472	Belongs to the glycosyl hydrolase 3 family
CEQ50_03750	COG3279	Response regulator of the LytR AlgR family
CEQ50_03755	COG3275	phosphorelay sensor kinase activity
CEQ50_03760	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEQ50_03765	COG0287	Prephenate dehydrogenase
CEQ50_03765	COG1605	Chorismate mutase
CEQ50_03775	COG0488	(ABC) transporter
CEQ50_03790	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CEQ50_03795	COG5001	Diguanylate cyclase
CEQ50_03800	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEQ50_03805	COG0077	Prephenate dehydratase
CEQ50_03805	COG1605	Chorismate mutase
CEQ50_03810	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEQ50_03815	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEQ50_03820	COG0564	pseudouridine synthase activity
CEQ50_03830	COG0542	response to heat
CEQ50_03840	COG1943	Transposase
CEQ50_03885	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEQ50_03900	COG0745	RESPONSE REGULATOR receiver
CEQ50_03905	COG5002	protein histidine kinase activity
CEQ50_03915	COG0248	Ppx GppA phosphatase
CEQ50_03920	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CEQ50_03930	COG0581	inorganic phosphate transmembrane transporter activity
CEQ50_03935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEQ50_03940	COG0704	Plays a role in the regulation of phosphate uptake
CEQ50_03945	COG3142	Participates in the control of copper homeostasis
CEQ50_03950	COG0450	alkyl hydroperoxide reductase
CEQ50_03955	COG0583	DNA-binding transcription factor activity
CEQ50_03960	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CEQ50_03970	COG0517	IMP dehydrogenase activity
CEQ50_03975	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CEQ50_03985	COG1862	Preprotein translocase
CEQ50_03990	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEQ50_03995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEQ50_04000	COG0483	inositol monophosphate 1-phosphatase activity
CEQ50_04005	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CEQ50_04010	COG1959	2 iron, 2 sulfur cluster binding
CEQ50_04020	COG0822	iron-sulfur transferase activity
CEQ50_04025	COG0316	Belongs to the HesB IscA family
CEQ50_04035	COG0443	Heat shock 70 kDa protein
CEQ50_04040	COG0633	Ferredoxin
CEQ50_04045	COG2975	iron-sulfur cluster assembly
CEQ50_04050	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEQ50_04065	COG1426	Protein conserved in bacteria
CEQ50_04070	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CEQ50_04075	COG0124	histidyl-tRNA synthetase
CEQ50_04080	COG2976	Protein conserved in bacteria
CEQ50_04085	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEQ50_04090	COG1160	GTP binding
CEQ50_04105	COG0516	GMP reductase activity
CEQ50_04105	COG0517	IMP dehydrogenase activity
CEQ50_04110	COG0519	Catalyzes the synthesis of GMP from XMP
CEQ50_04110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEQ50_04115	COG0351	phosphomethylpyrimidine kinase
CEQ50_04125	COG1584	GPR1 FUN34 yaaH family protein
CEQ50_04130	COG1115	amino acid carrier protein
CEQ50_04135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEQ50_04150	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CEQ50_04155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_04155	COG3711	transcriptional antiterminator
CEQ50_04170	COG3964	amidohydrolase
CEQ50_04200	COG0556	nucleotide-excision repair
CEQ50_04335	COG0582	viral genome integration into host DNA
CEQ50_04350	COG2867	negative regulation of translational initiation
CEQ50_04355	COG2914	Belongs to the UPF0125 (RnfH) family
CEQ50_04360	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEQ50_04365	COG0497	DNA recombination
CEQ50_04375	COG0814	amino acid
CEQ50_04385	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEQ50_04390	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEQ50_04395	COG0443	Heat shock 70 kDa protein
CEQ50_04400	COG0484	heat shock protein binding
CEQ50_04430	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CEQ50_04435	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CEQ50_04445	COG0583	DNA-binding transcription factor activity
CEQ50_04450	COG0590	tRNA wobble adenosine to inosine editing
CEQ50_04455	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CEQ50_04465	COG0047	phosphoribosylformylglycinamidine synthase activity
CEQ50_04465	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEQ50_04485	COG2979	Protein of unknown function (DUF533)
CEQ50_04490	COG0442	prolyl-tRNA aminoacylation
CEQ50_04495	COG1720	tRNA m6t6A37 methyltransferase activity
CEQ50_04505	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEQ50_04535	COG3098	single-species biofilm formation
CEQ50_04540	COG0564	pseudouridine synthase activity
CEQ50_04545	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEQ50_04550	COG0142	geranyltranstransferase activity
CEQ50_04560	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CEQ50_04570	COG0301	tRNA thio-modification
CEQ50_04570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEQ50_04575	COG0583	DNA-binding transcription factor activity
CEQ50_04580	COG2363	Small membrane protein
CEQ50_04590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEQ50_04595	COG1611	Belongs to the LOG family
CEQ50_04600	COG3706	GGDEF domain
CEQ50_04620	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CEQ50_04625	COG1464	Belongs to the NlpA lipoprotein family
CEQ50_04630	COG2011	ABC-type metal ion transport system permease component
CEQ50_04635	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEQ50_04640	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CEQ50_04655	COG1263	PTS System
CEQ50_04655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ50_04660	COG0366	Alpha amylase catalytic
CEQ50_04665	COG0745	RESPONSE REGULATOR receiver
CEQ50_04670	COG2205	protein histidine kinase activity
CEQ50_04705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ50_04710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ50_04715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEQ50_04720	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CEQ50_04725	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CEQ50_04730	COG0438	transferase activity, transferring glycosyl groups
CEQ50_04735	COG2244	polysaccharide biosynthetic process
CEQ50_04745	COG0438	transferase activity, transferring glycosyl groups
CEQ50_04775	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CEQ50_04820	COG0489	protein tyrosine kinase activity
CEQ50_04825	COG1596	polysaccharide export
CEQ50_04845	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEQ50_04860	COG0321	lipoyl(octanoyl) transferase activity
CEQ50_04865	COG2921	Belongs to the UPF0250 family
CEQ50_04870	COG1686	Belongs to the peptidase S11 family
CEQ50_04875	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CEQ50_04880	COG0772	Belongs to the SEDS family
CEQ50_04885	COG0768	penicillin binding
CEQ50_04890	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CEQ50_04895	COG0799	negative regulation of ribosome biogenesis
CEQ50_04900	COG1466	dna polymerase III delta subunit
CEQ50_04905	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CEQ50_04910	COG0495	leucyl-tRNA aminoacylation
CEQ50_04915	COG2888	peptidyl-tyrosine sulfation
CEQ50_04920	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CEQ50_04925	COG4535	Mg2 and Co2 transporter CorC
CEQ50_04935	COG1702	phosphate starvation-inducible protein PhoH
CEQ50_04940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEQ50_04945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEQ50_04950	COG2190	(PTS) system
CEQ50_04955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEQ50_04960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_04965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CEQ50_04970	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CEQ50_04975	COG3115	cell septum assembly
CEQ50_04995	COG0789	Transcriptional regulator
CEQ50_05005	COG0330	HflC and HflK could
CEQ50_05010	COG3118	belongs to the thioredoxin family
CEQ50_05015	COG1090	epimerase
CEQ50_05020	COG0622	Phosphoesterase
CEQ50_05035	COG3710	Transcriptional regulator
CEQ50_05040	COG0326	Molecular chaperone. Has ATPase activity
CEQ50_05050	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CEQ50_05055	COG3104	oligopeptide transport
CEQ50_05065	COG0367	asparagine synthase
CEQ50_05070	COG4651	solute:proton antiporter activity
CEQ50_05070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEQ50_05075	COG1846	Transcriptional regulator
CEQ50_05075	COG1940	carbohydrate kinase activity
CEQ50_05080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CEQ50_05085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ50_05085	COG2190	(PTS) system
CEQ50_05085	COG1263	PTS System
CEQ50_05090	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEQ50_05110	COG0285	dihydrofolate synthase activity
CEQ50_05115	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CEQ50_05120	COG1286	toxin biosynthetic process
CEQ50_05125	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CEQ50_05130	COG2056	Na+-H+ antiporter family
CEQ50_05135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEQ50_05145	COG0346	lactoylglutathione lyase activity
CEQ50_05150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEQ50_05165	COG4658	electron transport chain
CEQ50_05170	COG4656	Part of a membrane complex involved in electron transport
CEQ50_05175	COG2878	Part of a membrane complex involved in electron transport
CEQ50_05180	COG4657	Part of a membrane complex involved in electron transport
CEQ50_05190	COG1629	transport
CEQ50_05190	COG4774	siderophore transport
CEQ50_05195	COG2382	esterase
CEQ50_05215	COG3433	isochorismatase activity
CEQ50_05215	COG1535	isochorismatase
CEQ50_05220	COG1021	2,3-dihydroxybenzoate-AMP ligase
CEQ50_05225	COG1169	isochorismate synthase
CEQ50_05230	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ50_05235	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEQ50_05250	COG0556	nucleotide-excision repair
CEQ50_05255	COG2204	response regulator
CEQ50_05260	COG2198	Histidine kinase
CEQ50_05265	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CEQ50_05270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CEQ50_05275	COG0521	Mo-molybdopterin cofactor biosynthetic process
CEQ50_05285	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CEQ50_05290	COG0314	molybdopterin synthase activity
CEQ50_05295	COG2199	diguanylate cyclase activity
CEQ50_05300	COG4109	DRTGG domain
CEQ50_05310	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CEQ50_05320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ50_05320	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ50_05325	COG0489	protein tyrosine kinase activity
CEQ50_05330	COG0572	uridine kinase
CEQ50_05335	COG2982	Protein involved in outer membrane biogenesis
CEQ50_05340	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CEQ50_05345	COG2067	long-chain fatty acid transport protein
CEQ50_05350	COG2067	long-chain fatty acid transport protein
CEQ50_05360	COG1595	DNA-templated transcription, initiation
CEQ50_05370	COG0183	Belongs to the thiolase family
CEQ50_05375	COG1024	Enoyl-CoA hydratase
CEQ50_05375	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEQ50_05380	COG0778	Nitroreductase
CEQ50_05385	COG0583	DNA-binding transcription factor activity
CEQ50_05390	COG0745	RESPONSE REGULATOR receiver
CEQ50_05400	COG2832	Protein of unknown function (DUF454)
CEQ50_05405	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEQ50_05415	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CEQ50_05445	COG2226	methyltransferase
CEQ50_05460	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ50_05470	COG3139	Protein of unknown function (DUF1315)
CEQ50_05475	COG0252	asparaginase activity
CEQ50_05480	COG0616	signal peptide processing
CEQ50_05485	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEQ50_05485	COG1902	pentaerythritol trinitrate reductase activity
CEQ50_05490	COG0788	formyltetrahydrofolate deformylase activity
CEQ50_05500	COG1199	ATP-dependent helicase activity
CEQ50_05505	COG1214	PFAM Peptidase M22, glycoprotease
CEQ50_05520	COG0596	Alpha beta hydrolase
CEQ50_05525	COG0318	PFAM AMP-dependent synthetase and ligase
CEQ50_05530	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CEQ50_05540	COG2894	cell division
CEQ50_05550	COG3100	YcgL domain-containing protein
CEQ50_05555	COG2951	lytic endotransglycosylase activity
CEQ50_05560	COG0583	DNA-binding transcription factor activity
CEQ50_05565	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEQ50_05590	COG4628	conserved protein (DUF2132)
CEQ50_05605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEQ50_05615	COG0513	Belongs to the DEAD box helicase family
CEQ50_05625	COG1760	l-serine dehydratase
CEQ50_05630	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CEQ50_05635	COG0745	RESPONSE REGULATOR receiver
CEQ50_05640	COG2205	protein histidine kinase activity
CEQ50_05645	COG1653	transport
CEQ50_05655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEQ50_05660	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CEQ50_05665	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEQ50_05685	COG0544	peptidyl-prolyl cis-trans isomerase activity
CEQ50_05700	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CEQ50_05705	COG0776	regulation of translation
CEQ50_05710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEQ50_05715	COG1555	photosystem II stabilization
CEQ50_05720	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CEQ50_05725	COG0539	negative regulation of cytoplasmic translation
CEQ50_05735	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CEQ50_05740	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CEQ50_05755	COG0583	DNA-binding transcription factor activity
CEQ50_05765	COG0686	Belongs to the AlaDH PNT family
CEQ50_05770	COG1522	sequence-specific DNA binding
CEQ50_05775	COG1674	ftsk spoiiie
CEQ50_05785	COG0501	Belongs to the peptidase M48B family
CEQ50_05795	COG0300	oxidoreductase activity
CEQ50_05810	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CEQ50_05820	COG2268	Band 7 protein
CEQ50_05830	COG1032	radical SAM domain protein
CEQ50_05840	COG2199	diguanylate cyclase activity
CEQ50_05840	COG2200	EAL domain
CEQ50_05840	COG2203	Gaf domain
CEQ50_05855	COG0583	DNA-binding transcription factor activity
CEQ50_05860	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEQ50_05870	COG1943	Transposase
CEQ50_05880	COG2350	Protein conserved in bacteria
CEQ50_05885	COG1607	acyl-coa hydrolase
CEQ50_05915	COG0133	tryptophan synthase activity
CEQ50_05920	COG0135	phosphoribosylanthranilate isomerase activity
CEQ50_05920	COG0134	indole-3-glycerol-phosphate synthase activity
CEQ50_05925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEQ50_05930	COG0512	Glutamine amidotransferase of anthranilate synthase
CEQ50_05935	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CEQ50_05945	COG0613	PHP domain protein
CEQ50_05950	COG0009	L-threonylcarbamoyladenylate synthase
CEQ50_05955	COG1187	pseudouridine synthase activity
CEQ50_05965	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CEQ50_05970	COG4988	ABC transporter
CEQ50_05975	COG0492	ferredoxin-NADP+ reductase activity
CEQ50_05980	COG3706	GGDEF domain
CEQ50_05980	COG0745	RESPONSE REGULATOR receiver
CEQ50_05995	COG2949	membrane
CEQ50_06005	COG0281	malic enzyme
CEQ50_06025	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CEQ50_06035	COG1737	Transcriptional regulator
CEQ50_06040	COG0076	glutamate decarboxylase activity
CEQ50_06050	COG2431	L-lysine efflux transmembrane transporter activity
CEQ50_06060	COG3070	regulator of competence-specific genes
CEQ50_06075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ50_06075	COG4191	Histidine kinase
CEQ50_06085	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CEQ50_06090	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CEQ50_06095	COG2915	High frequency lysogenization protein hflD homolog
CEQ50_06100	COG0482	sulfurtransferase activity
CEQ50_06110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ50_06115	COG2916	Histone family protein nucleoid-structuring protein H-NS
CEQ50_06120	COG1757	Na H antiporter
CEQ50_06130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEQ50_06135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEQ50_06140	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CEQ50_06140	COG0131	Imidazoleglycerol-phosphate dehydratase
CEQ50_06145	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CEQ50_06150	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CEQ50_06155	COG0107	imidazoleglycerol-phosphate synthase activity
CEQ50_06160	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CEQ50_06160	COG0140	phosphoribosyl-ATP diphosphatase activity
CEQ50_06165	COG1187	pseudouridine synthase activity
CEQ50_06175	COG1278	Cold shock
CEQ50_06180	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CEQ50_06185	COG0542	response to heat
CEQ50_06190	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CEQ50_06195	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CEQ50_06200	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CEQ50_06205	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CEQ50_06215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEQ50_06220	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEQ50_06225	COG0297	glycogen (starch) synthase activity
CEQ50_06245	COG3070	regulator of competence-specific genes
CEQ50_06250	COG1609	Transcriptional regulator
CEQ50_06260	COG0745	RESPONSE REGULATOR receiver
CEQ50_06265	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CEQ50_06270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEQ50_06280	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CEQ50_06285	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CEQ50_06300	COG0189	ligase activity
CEQ50_06300	COG4067	protein conserved in archaea
CEQ50_06305	COG0500	methyltransferase
CEQ50_06310	COG4106	trans-aconitate 2-methyltransferase activity
CEQ50_06315	COG1801	Protein of unknown function DUF72
CEQ50_06320	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CEQ50_06325	COG1435	thymidine kinase activity
CEQ50_06355	COG2116	formate transmembrane transporter activity
CEQ50_06365	COG1943	Transposase
CEQ50_06370	COG4459	periplasmic nitrate reductase
CEQ50_06375	COG3005	denitrification pathway
CEQ50_06380	COG0243	molybdopterin cofactor binding
CEQ50_06390	COG1227	inorganic diphosphatase activity
CEQ50_06400	COG2814	Major facilitator Superfamily
CEQ50_06415	COG4172	Belongs to the ABC transporter superfamily
CEQ50_06425	COG4171	peptide transport system, permease
CEQ50_06430	COG4168	peptide transport system, permease
CEQ50_06440	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CEQ50_06445	COG1842	Phage shock protein A
CEQ50_06460	COG0519	Catalyzes the synthesis of GMP from XMP
CEQ50_06465	COG0626	cystathionine gamma-synthase activity
CEQ50_06475	COG0733	neurotransmitter:sodium symporter activity
CEQ50_06480	COG0564	pseudouridine synthase activity
CEQ50_06490	COG2200	EAL domain
CEQ50_06495	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CEQ50_06500	COG4136	ATPase activity
CEQ50_06505	COG4135	transport system, permease component
CEQ50_06510	COG4134	Bacterial extracellular solute-binding protein
CEQ50_06520	COG3313	Fe-S protein
CEQ50_06530	COG0737	Belongs to the 5'-nucleotidase family
CEQ50_06540	COG0513	Belongs to the DEAD box helicase family
CEQ50_06560	COG2205	protein histidine kinase activity
CEQ50_06575	COG1061	Type III restriction enzyme res subunit
CEQ50_06580	COG1187	pseudouridine synthase activity
CEQ50_06585	COG2814	Major facilitator Superfamily
CEQ50_06595	COG0702	epimerase
CEQ50_06600	COG0534	Mate efflux family protein
CEQ50_06605	COG4181	ATPase activity
CEQ50_06620	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CEQ50_06640	COG0019	diaminopimelate decarboxylase activity
CEQ50_06675	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEQ50_06680	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEQ50_06685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEQ50_06695	COG0840	transmembrane signaling receptor activity
CEQ50_06710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ50_06710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ50_06710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_06715	COG2207	Transcriptional regulator
CEQ50_06725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ50_06735	COG1342	Belongs to the UPF0251 family
CEQ50_06755	COG1129	ABC transporter
CEQ50_06765	COG0583	DNA-binding transcription factor activity
CEQ50_06770	COG1902	pentaerythritol trinitrate reductase activity
CEQ50_06775	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEQ50_06780	COG5002	protein histidine kinase activity
CEQ50_06785	COG0745	RESPONSE REGULATOR receiver
CEQ50_06815	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CEQ50_06820	COG0372	Belongs to the citrate synthase family
CEQ50_06825	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CEQ50_06830	COG2828	Protein conserved in bacteria
CEQ50_06850	COG0561	phosphatase activity
CEQ50_06855	COG0602	queuosine metabolic process
CEQ50_06895	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEQ50_06900	COG1254	Belongs to the acylphosphatase family
CEQ50_06905	COG2920	part of a sulfur-relay system
CEQ50_06910	COG0670	Belongs to the BI1 family
CEQ50_06915	COG1126	abc transporter atp-binding protein
CEQ50_06920	COG0765	amino acid transport
CEQ50_06925	COG4597	amino acid ABC transporter
CEQ50_06930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ50_06935	COG1648	precorrin-2 dehydrogenase activity
CEQ50_06935	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEQ50_06945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEQ50_06950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEQ50_06950	COG0574	Belongs to the PEP-utilizing enzyme family
CEQ50_06965	COG2996	Protein conserved in bacteria
CEQ50_06975	COG3008	intermembrane lipid transfer
CEQ50_06980	COG2995	paraquat-inducible protein a
CEQ50_06985	COG1132	(ABC) transporter
CEQ50_06990	COG1956	GAF domain-containing protein
CEQ50_07010	COG0308	aminopeptidase N
CEQ50_07020	COG2902	Dehydrogenase
CEQ50_07025	COG0167	dihydroorotate dehydrogenase activity
CEQ50_07035	COG0116	Belongs to the methyltransferase superfamily
CEQ50_07035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEQ50_07060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEQ50_07065	COG1067	ATP-dependent peptidase activity
CEQ50_07070	COG3120	sequence-specific DNA binding
CEQ50_07120	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEQ50_07150	COG0583	DNA-binding transcription factor activity
CEQ50_07155	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CEQ50_07165	COG3278	Belongs to the heme-copper respiratory oxidase family
CEQ50_07180	COG2010	Cytochrome c
CEQ50_07190	COG2217	Heavy metal translocating P-type atpase
CEQ50_07205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEQ50_07210	COG0589	response to stress
CEQ50_07235	COG3842	ATPase activity
CEQ50_07240	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEQ50_07245	COG1177	transmembrane transport
CEQ50_07250	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEQ50_07255	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEQ50_07265	COG1943	Transposase
CEQ50_07270	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEQ50_07275	COG0004	ammonium transporteR
CEQ50_07280	COG0488	(ABC) transporter
CEQ50_07285	COG2197	response regulator
CEQ50_07295	COG2271	Major facilitator Superfamily
CEQ50_07300	COG1840	ABC-type Fe3 transport system, periplasmic component
CEQ50_07310	COG3842	ATPase activity
CEQ50_07315	COG0746	molybdenum cofactor guanylyltransferase activity
CEQ50_07320	COG1763	Mo-molybdopterin cofactor biosynthetic process
CEQ50_07345	COG0840	transmembrane signaling receptor activity
CEQ50_07350	COG0791	NLP P60 protein
CEQ50_07375	COG1793	dna ligase
CEQ50_07380	COG4667	esterase of the alpha-beta hydrolase superfamily
CEQ50_07395	COG0848	biopolymer transport protein
CEQ50_07400	COG0811	peptide transport
CEQ50_07405	COG0811	peptide transport
CEQ50_07435	COG0625	glutathione transferase activity
CEQ50_07445	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CEQ50_07455	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEQ50_07470	COG1115	amino acid carrier protein
CEQ50_07475	COG1280	lysine exporter protein (LysE YggA)
CEQ50_07480	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CEQ50_07485	COG0477	Major facilitator Superfamily
CEQ50_07490	COG0583	DNA-binding transcription factor activity
CEQ50_07500	COG1643	Atp-dependent helicase
CEQ50_07520	COG3706	GGDEF domain
CEQ50_07535	COG0443	Heat shock 70 kDa protein
CEQ50_07565	COG1609	Transcriptional regulator
CEQ50_07570	COG2723	6-phospho-beta-galactosidase activity
CEQ50_07575	COG0513	Belongs to the DEAD box helicase family
CEQ50_07580	COG0243	molybdopterin cofactor binding
CEQ50_07585	COG3005	denitrification pathway
CEQ50_07590	COG1278	Cold shock
CEQ50_07605	COG4191	Histidine kinase
CEQ50_07605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ50_07610	COG0471	metal ion transport
CEQ50_07620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEQ50_07630	COG3706	GGDEF domain
CEQ50_07640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEQ50_07645	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CEQ50_07650	COG3768	UPF0283 membrane protein
CEQ50_07655	COG3106	COG3106 Predicted ATPase
CEQ50_07680	COG0814	amino acid
CEQ50_07685	COG1760	l-serine dehydratase
CEQ50_07695	COG2356	endonuclease I
CEQ50_07700	COG0720	synthase
CEQ50_07705	COG0840	transmembrane signaling receptor activity
CEQ50_07710	COG0017	Asparaginyl-tRNA synthetase
CEQ50_07720	COG2201	protein-glutamate methylesterase activity
CEQ50_07725	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CEQ50_07730	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CEQ50_07735	COG0835	chemotaxis
CEQ50_07745	COG2198	Histidine kinase
CEQ50_07745	COG0643	Histidine kinase
CEQ50_07755	COG0745	RESPONSE REGULATOR receiver
CEQ50_07765	COG3437	response regulator, receiver
CEQ50_07765	COG2770	Histidine kinase
CEQ50_07770	COG1448	Aminotransferase
CEQ50_07775	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CEQ50_07785	COG0840	transmembrane signaling receptor activity
CEQ50_07790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEQ50_07795	COG1846	Transcriptional regulator
CEQ50_07810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEQ50_07815	COG3108	Peptidase M15
CEQ50_07820	COG2989	Protein conserved in bacteria
CEQ50_07850	COG1940	carbohydrate kinase activity
CEQ50_07855	COG4771	TonB-dependent receptor
CEQ50_07860	COG0748	coenzyme F420 binding
CEQ50_07865	COG3721	Heme iron utilization protein
CEQ50_07875	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CEQ50_07880	COG0811	peptide transport
CEQ50_07885	COG0848	biopolymer transport protein
CEQ50_07895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEQ50_07900	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CEQ50_07920	COG1621	beta-fructofuranosidase activity
CEQ50_07930	COG1263	PTS System
CEQ50_07930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ50_07935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ50_07940	COG2200	EAL domain
CEQ50_07945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEQ50_07950	COG0840	transmembrane signaling receptor activity
CEQ50_07955	COG1294	oxidase, subunit
CEQ50_07960	COG1271	oxidase subunit
CEQ50_07985	COG3220	belongs to the UPF0276 family
CEQ50_08005	COG1294	oxidase, subunit
CEQ50_08015	COG0251	oxidation-reduction process
CEQ50_08050	COG2963	transposase activity
CEQ50_08100	COG3064	Membrane
CEQ50_08100	COG0515	serine threonine protein kinase
CEQ50_08100	COG4991	sh3 domain protein
CEQ50_08125	COG1716	ATPase activity
CEQ50_08145	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEQ50_08195	COG3501	Rhs element vgr protein
CEQ50_08220	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CEQ50_08245	COG0745	RESPONSE REGULATOR receiver
CEQ50_08245	COG3706	GGDEF domain
CEQ50_08260	COG0784	Response regulator, receiver
CEQ50_08260	COG0835	chemotaxis
CEQ50_08270	COG4565	transcriptional regulatory protein
CEQ50_08275	COG3290	protein histidine kinase activity
CEQ50_08290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ50_08315	COG3063	Type IV pilus biogenesis stability protein PilW
CEQ50_08330	COG1451	nucleotide metabolic process
CEQ50_08340	COG0583	DNA-binding transcription factor activity
CEQ50_08360	COG1943	Transposase
CEQ50_08375	COG4139	cobalamin transport
CEQ50_08380	COG2988	succinylglutamate desuccinylase activity
CEQ50_08395	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CEQ50_08415	COG2994	toxin metabolic process
CEQ50_08445	COG0702	epimerase
CEQ50_08455	COG2925	Exonuclease
CEQ50_08465	COG1346	cytolysis
CEQ50_08470	COG0295	cytidine deaminase activity
CEQ50_08475	COG5001	Diguanylate cyclase
CEQ50_08480	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CEQ50_08490	COG0500	methyltransferase
CEQ50_08505	COG0072	phenylalanine-tRNA ligase activity
CEQ50_08505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ50_08550	COG0322	excinuclease ABC activity
CEQ50_08555	COG2197	response regulator
CEQ50_08585	COG2433	Pfam Transposase IS66
CEQ50_08610	COG0417	DNA replication proofreading
CEQ50_08675	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEQ50_08680	COG3099	Belongs to the UPF0263 family
CEQ50_08695	COG1228	amidohydrolase
CEQ50_08700	COG0010	Belongs to the arginase family
CEQ50_08710	COG2986	histidine ammonia-lyase
CEQ50_08725	COG0247	lactate metabolic process
CEQ50_08725	COG0277	FAD linked oxidase domain protein
CEQ50_08755	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEQ50_08760	COG1960	acyl-CoA dehydrogenase activity
CEQ50_08790	COG5001	Diguanylate cyclase
CEQ50_08790	COG3300	MHYT domain
CEQ50_08810	COG2433	Pfam Transposase IS66
CEQ50_08830	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CEQ50_08850	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CEQ50_08870	COG0494	nUDIX hydrolase
CEQ50_08940	COG2003	Belongs to the UPF0758 family
CEQ50_08955	COG0328	RNA-DNA hybrid ribonuclease activity
CEQ50_08995	COG0582	viral genome integration into host DNA
CEQ50_09010	COG5002	protein histidine kinase activity
CEQ50_09010	COG0784	Response regulator, receiver
CEQ50_09020	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CEQ50_09025	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CEQ50_09030	COG2885	chlorophyll binding
CEQ50_09050	COG0811	peptide transport
CEQ50_09055	COG0824	Thioesterase
CEQ50_09060	COG3790	cyd operon protein YbgE
CEQ50_09065	COG4890	Cyd operon protein YbgT
CEQ50_09070	COG1294	oxidase, subunit
CEQ50_09075	COG1271	oxidase subunit
CEQ50_09080	COG2255	four-way junction helicase activity
CEQ50_09085	COG0632	four-way junction helicase activity
CEQ50_09090	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CEQ50_09095	COG0215	cysteine-tRNA ligase activity
CEQ50_09100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEQ50_09105	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEQ50_09110	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CEQ50_09115	COG3012	SEC-C Motif Domain Protein
CEQ50_09125	COG1199	ATP-dependent helicase activity
CEQ50_09135	COG3923	Primosomal replication protein n
CEQ50_09145	COG0840	transmembrane signaling receptor activity
CEQ50_09150	COG0708	Exodeoxyribonuclease III
CEQ50_09155	COG4160	amino acid transport
CEQ50_09160	COG4215	(ABC) transporter
CEQ50_09185	COG1882	Formate acetyltransferase
CEQ50_09200	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEQ50_09215	COG2766	serine protein kinase
CEQ50_09220	COG2718	Belongs to the UPF0229 family
CEQ50_09225	COG2719	SpoVR family
CEQ50_09230	COG3038	cytochrome b561
CEQ50_09235	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CEQ50_09250	COG1132	(ABC) transporter
CEQ50_09255	COG0658	competence protein
CEQ50_09255	COG2333	competence protein COMEC
CEQ50_09265	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEQ50_09270	COG1136	(ABC) transporter
CEQ50_09275	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEQ50_09285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEQ50_09300	COG1252	NADH dehydrogenase
CEQ50_09330	COG0537	adenosine 5'-monophosphoramidase activity
CEQ50_09345	COG2186	Transcriptional regulator
CEQ50_09350	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CEQ50_09360	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CEQ50_09365	COG2226	methyltransferase
CEQ50_09370	COG0156	8-amino-7-oxononanoate synthase activity
CEQ50_09380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CEQ50_09390	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEQ50_09395	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CEQ50_09400	COG0653	protein targeting
CEQ50_09405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEQ50_09415	COG4120	Belongs to the binding-protein-dependent transport system permease family
CEQ50_09425	COG3092	negative regulation of chromosome organization
CEQ50_09430	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEQ50_09435	COG0280	phosphate acetyltransferase
CEQ50_09435	COG0857	belongs to the CobB CobQ family
CEQ50_09440	COG0435	Glutathione S-transferase
CEQ50_09450	COG0444	Belongs to the ABC transporter superfamily
CEQ50_09455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEQ50_09460	COG0601	transmembrane transport
CEQ50_09475	COG0784	Response regulator, receiver
CEQ50_09475	COG5002	protein histidine kinase activity
CEQ50_09500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEQ50_09505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEQ50_09525	COG1215	transferase activity, transferring glycosyl groups
CEQ50_09555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEQ50_09560	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEQ50_09565	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ50_09580	COG1335	isochorismatase
CEQ50_09595	COG1538	Outer membrane efflux protein
CEQ50_09600	COG1566	PFAM secretion protein HlyD family protein
CEQ50_09615	COG0800	Aldolase
CEQ50_09620	COG2610	gluconate transmembrane transporter activity
CEQ50_09625	COG3265	gluconokinase activity
CEQ50_09630	COG0129	dihydroxy-acid dehydratase activity
CEQ50_09635	COG1609	Transcriptional regulator
CEQ50_09650	COG3850	Histidine kinase
CEQ50_09650	COG5002	protein histidine kinase activity
CEQ50_09660	COG2985	domain, Protein
CEQ50_09675	COG2194	sulfuric ester hydrolase activity
CEQ50_09680	COG0642	Histidine kinase
CEQ50_09685	COG0745	RESPONSE REGULATOR receiver
CEQ50_09705	COG1022	Amp-dependent synthetase and ligase
CEQ50_09730	COG3706	GGDEF domain
CEQ50_09745	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CEQ50_09750	COG1946	Acyl-CoA thioesterase
CEQ50_09755	COG1522	sequence-specific DNA binding
CEQ50_09790	COG0318	PFAM AMP-dependent synthetase and ligase
CEQ50_09795	COG1441	menaquinone biosynthetic process
CEQ50_09800	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CEQ50_09810	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CEQ50_09825	COG0436	Aminotransferase
CEQ50_09830	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CEQ50_09835	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CEQ50_09850	COG0616	signal peptide processing
CEQ50_09855	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ50_09860	COG0784	Response regulator, receiver
CEQ50_09860	COG0835	chemotaxis
CEQ50_09865	COG1940	carbohydrate kinase activity
CEQ50_09875	COG4667	esterase of the alpha-beta hydrolase superfamily
CEQ50_09885	COG0733	neurotransmitter:sodium symporter activity
CEQ50_09895	COG1263	PTS System
CEQ50_09895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ50_09900	COG0084	hydrolase, TatD family'
CEQ50_09905	COG0470	DNA polymerase III
CEQ50_09910	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CEQ50_09915	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CEQ50_09920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEQ50_09945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEQ50_09955	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CEQ50_09960	COG1399	metal-binding, possibly nucleic acid-binding protein
CEQ50_09965	COG0424	maF-like protein
CEQ50_09970	COG0564	pseudouridine synthase activity
CEQ50_09975	COG1530	ribonuclease E activity
CEQ50_09985	COG1454	alcohol dehydrogenase
CEQ50_09985	COG1012	belongs to the aldehyde dehydrogenase family
CEQ50_09990	COG2095	MarC family integral membrane protein
CEQ50_09995	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEQ50_10015	COG3082	Protein of unknown function (DUF1414)
CEQ50_10020	COG3083	sulfuric ester hydrolase activity
CEQ50_10030	COG0243	molybdopterin cofactor binding
CEQ50_10035	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CEQ50_10055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEQ50_10060	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CEQ50_10080	COG2853	Lipoprotein
CEQ50_10095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEQ50_10100	COG1138	Cytochrome C-type biogenesis protein
CEQ50_10105	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CEQ50_10115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEQ50_10120	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEQ50_10125	COG4133	protoheme IX ABC transporter activity
CEQ50_10135	COG0835	chemotaxis
CEQ50_10145	COG1192	Involved in chromosome partitioning
CEQ50_10150	COG2201	protein-glutamate methylesterase activity
CEQ50_10155	COG0643	Histidine kinase
CEQ50_10155	COG2198	Histidine kinase
CEQ50_10160	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CEQ50_10175	COG0455	bacterial-type flagellum organization
CEQ50_10185	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CEQ50_10190	COG2062	phosphohistidine phosphatase, SixA
CEQ50_10195	COG1025	Belongs to the peptidase M16 family
CEQ50_10200	COG3102	Protein conserved in bacteria
CEQ50_10225	COG1918	ferrous iron import across plasma membrane
CEQ50_10230	COG4977	sequence-specific DNA binding
CEQ50_10235	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CEQ50_10240	COG1121	(ABC) transporter
CEQ50_10245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEQ50_10260	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEQ50_10265	COG0567	Dehydrogenase, E1 component
CEQ50_10280	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CEQ50_10285	COG2009	succinate dehydrogenase
CEQ50_10295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CEQ50_10305	COG0033	Phosphoglucomutase
CEQ50_10310	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CEQ50_10315	COG0596	Alpha beta hydrolase
CEQ50_10325	COG0716	FMN binding
CEQ50_10330	COG1346	cytolysis
CEQ50_10340	COG0583	DNA-binding transcription factor activity
CEQ50_10350	COG0735	belongs to the Fur family
CEQ50_10355	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEQ50_10360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEQ50_10365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEQ50_10370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEQ50_10370	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CEQ50_10375	COG0431	NADPH-dependent FMN reductase
CEQ50_10385	COG3101	peptidyl-lysine hydroxylation
CEQ50_10390	COG2860	membrane
CEQ50_10395	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CEQ50_10400	COG2890	protein-(glutamine-N5) methyltransferase activity
CEQ50_10405	COG2840	Smr protein MutS2
CEQ50_10415	COG1684	flagellar biosynthetic protein fliR
CEQ50_10420	COG1987	bacterial-type flagellum assembly
CEQ50_10470	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CEQ50_10480	COG1677	Flagellar hook-basal body complex protein FliE
CEQ50_10485	COG2204	response regulator
CEQ50_10490	COG4191	Histidine kinase
CEQ50_10495	COG2204	response regulator
CEQ50_10500	COG1516	flagellar protein fliS
CEQ50_10510	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CEQ50_10535	COG2837	iron assimilation
CEQ50_10560	COG1393	Belongs to the ArsC family
CEQ50_10565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEQ50_10585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEQ50_10595	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEQ50_10615	COG4783	chaperone-mediated protein folding
CEQ50_10620	COG1393	Belongs to the ArsC family
CEQ50_10640	COG2233	PERMEase
CEQ50_10645	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEQ50_10655	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CEQ50_10660	COG2912	Transglutaminase-like superfamily
CEQ50_10665	COG3094	Invasion gene expression up-regulator, SirB
CEQ50_10670	COG2890	protein-(glutamine-N5) methyltransferase activity
CEQ50_10675	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CEQ50_10680	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CEQ50_10685	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CEQ50_10700	COG0193	aminoacyl-tRNA hydrolase activity
CEQ50_10805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CEQ50_10815	COG3951	Flagellar rod assembly protein muramidase FlgJ
CEQ50_10815	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEQ50_10820	COG1706	bacterial-type flagellum-dependent cell motility
CEQ50_10825	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CEQ50_10830	COG4786	Flagellar basal body rod
CEQ50_10835	COG4787	bacterial-type flagellum-dependent cell motility
CEQ50_10840	COG1749	Flagellar hook protein flgE
CEQ50_10845	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CEQ50_10850	COG1558	bacterial-type flagellum-dependent cell motility
CEQ50_10855	COG1815	bacterial-type flagellum-dependent cell motility
CEQ50_10865	COG0835	chemotaxis
CEQ50_10865	COG0784	Response regulator, receiver
CEQ50_10875	COG2747	anti-sigma28 factor FlgM
CEQ50_10920	COG2217	Heavy metal translocating P-type atpase
CEQ50_10920	COG2608	mercury ion transmembrane transporter activity
CEQ50_10945	COG1187	pseudouridine synthase activity
CEQ50_10950	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEQ50_10955	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CEQ50_10960	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CEQ50_10965	COG0121	glutamine amidotransferase
CEQ50_10970	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CEQ50_10985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEQ50_10995	COG2226	methyltransferase
CEQ50_11000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEQ50_11005	COG0741	lytic transglycosylase activity
CEQ50_11005	COG1388	LysM domain
CEQ50_11020	COG0347	Belongs to the P(II) protein family
CEQ50_11030	COG0037	tRNA processing
CEQ50_11035	COG0825	malonyl-CoA metabolic process
CEQ50_11040	COG0587	DNA-directed DNA polymerase activity
CEQ50_11050	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEQ50_11060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEQ50_11065	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEQ50_11070	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CEQ50_11080	COG0750	zinc metalloprotease
CEQ50_11085	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CEQ50_11090	COG0575	Belongs to the CDS family
CEQ50_11095	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CEQ50_11100	COG0233	cytoplasmic translational termination
CEQ50_11110	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CEQ50_11115	COG0052	Belongs to the universal ribosomal protein uS2 family
CEQ50_11120	COG0024	Methionine aminopeptidase
CEQ50_11135	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CEQ50_11140	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CEQ50_11165	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEQ50_11165	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEQ50_11175	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CEQ50_11180	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CEQ50_11200	COG2252	PERMEase
CEQ50_11205	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEQ50_11210	COG4067	protein conserved in archaea
CEQ50_11210	COG0189	ligase activity
CEQ50_11215	COG0189	ligase activity
CEQ50_11225	COG0733	neurotransmitter:sodium symporter activity
CEQ50_11255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEQ50_11265	COG1477	protein flavinylation
CEQ50_11300	COG0271	Belongs to the BolA IbaG family
CEQ50_11320	COG2211	Major facilitator Superfamily
CEQ50_11330	COG1595	DNA-templated transcription, initiation
CEQ50_11345	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEQ50_11355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CEQ50_11360	COG2166	iron-sulfur cluster assembly
CEQ50_11365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CEQ50_11370	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CEQ50_11380	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CEQ50_11380	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEQ50_11390	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEQ50_11395	COG1074	ATP-dependent DNA helicase activity
CEQ50_11400	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CEQ50_11415	COG3141	response to X-ray
CEQ50_11420	COG2171	N-acyltransferase activity
CEQ50_11450	COG1609	Transcriptional regulator
CEQ50_11460	COG1085	galactose-1-phosphate uridylyltransferase
CEQ50_11465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEQ50_11470	COG0534	Mate efflux family protein
CEQ50_11480	COG3437	response regulator, receiver
CEQ50_11480	COG0784	Response regulator, receiver
CEQ50_11485	COG1022	Amp-dependent synthetase and ligase
CEQ50_11490	COG4628	conserved protein (DUF2132)
CEQ50_11495	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEQ50_11500	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CEQ50_11510	COG0560	Phosphoserine phosphatase
CEQ50_11520	COG0813	purine-nucleoside phosphorylase activity
CEQ50_11525	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CEQ50_11535	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CEQ50_11540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEQ50_11545	COG0084	hydrolase, TatD family'
CEQ50_11555	COG1115	amino acid carrier protein
CEQ50_11570	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CEQ50_11575	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CEQ50_11580	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CEQ50_11585	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CEQ50_11590	COG0083	homoserine kinase activity
CEQ50_11605	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CEQ50_11610	COG0745	RESPONSE REGULATOR receiver
CEQ50_11620	COG0784	Response regulator, receiver
CEQ50_11620	COG2198	Histidine kinase
CEQ50_11620	COG5002	protein histidine kinase activity
CEQ50_11625	COG1242	4 iron, 4 sulfur cluster binding
CEQ50_11635	COG0067	glutamate synthase
CEQ50_11635	COG0069	glutamate synthase activity
CEQ50_11635	COG0070	glutamate synthase
CEQ50_11645	COG0070	glutamate synthase
CEQ50_11645	COG0069	glutamate synthase activity
CEQ50_11645	COG0067	glutamate synthase
CEQ50_11650	COG0493	'glutamate synthase
CEQ50_11675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEQ50_11680	COG2860	membrane
CEQ50_11685	COG0583	DNA-binding transcription factor activity
CEQ50_11690	COG0730	response to heat
CEQ50_11700	COG0505	Belongs to the CarA family
CEQ50_11710	COG0494	nUDIX hydrolase
CEQ50_11715	COG1943	Transposase
CEQ50_11725	COG0653	protein targeting
CEQ50_11735	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CEQ50_11740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CEQ50_11745	COG0849	cell division
CEQ50_11750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CEQ50_11755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEQ50_11760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CEQ50_11765	COG0772	Belongs to the SEDS family
CEQ50_11770	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CEQ50_11775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEQ50_11780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEQ50_11785	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CEQ50_11790	COG0768	penicillin binding
CEQ50_11795	COG3116	cell division
CEQ50_11810	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CEQ50_11815	COG3107	peptidoglycan biosynthetic process
CEQ50_11825	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CEQ50_11835	COG2969	positive regulation of protein catabolic process
CEQ50_11840	COG0625	glutathione transferase activity
CEQ50_11845	COG2857	Cytochrome c1
CEQ50_11850	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CEQ50_11855	COG0723	plastoquinol--plastocyanin reductase activity
CEQ50_11875	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CEQ50_11880	COG3105	Protein conserved in bacteria
CEQ50_11885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEQ50_11890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEQ50_11895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CEQ50_11900	COG0187	DNA topoisomerase II activity
CEQ50_11905	COG3150	esterase
CEQ50_11915	COG3151	Protein conserved in bacteria
CEQ50_11920	COG0494	nUDIX hydrolase
CEQ50_11925	COG1538	Outer membrane efflux protein
CEQ50_11935	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CEQ50_11950	COG3025	triphosphatase activity
CEQ50_11955	COG1392	Phosphate transport regulator
CEQ50_11960	COG0306	phosphate transporter
CEQ50_11965	COG4991	sh3 domain protein
CEQ50_11975	COG3267	Type II secretory pathway component ExeA
CEQ50_11975	COG3409	Peptidoglycan-binding domain 1 protein
CEQ50_11980	COG0617	tRNA 3'-terminal CCA addition
CEQ50_11990	COG0504	CTP synthase activity
CEQ50_11995	COG3956	TIGRFAM MazG family protein
CEQ50_12000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEQ50_12005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEQ50_12010	COG4999	Histidine kinase
CEQ50_12010	COG3850	Histidine kinase
CEQ50_12010	COG3437	response regulator, receiver
CEQ50_12010	COG2205	protein histidine kinase activity
CEQ50_12015	COG0736	holo-[acyl-carrier-protein] synthase activity
CEQ50_12040	COG0681	Belongs to the peptidase S26 family
CEQ50_12045	COG0481	GTPase activity
CEQ50_12050	COG3086	response to oxidative stress
CEQ50_12065	COG1595	DNA-templated transcription, initiation
CEQ50_12070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CEQ50_12080	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CEQ50_12085	COG0354	folic acid binding
CEQ50_12100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEQ50_12105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEQ50_12115	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CEQ50_12125	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CEQ50_12135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEQ50_12140	COG1943	Transposase
CEQ50_12155	COG0028	Belongs to the TPP enzyme family
CEQ50_12160	COG1022	Amp-dependent synthetase and ligase
CEQ50_12165	COG0583	DNA-binding transcription factor activity
CEQ50_12180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEQ50_12185	COG0473	3-isopropylmalate dehydrogenase activity
CEQ50_12195	COG0066	3-isopropylmalate dehydratase activity
CEQ50_12255	COG0795	lipopolysaccharide-transporting ATPase activity
CEQ50_12260	COG0795	lipopolysaccharide-transporting ATPase activity
CEQ50_12265	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEQ50_12270	COG2927	DNA polymerase III (CHI subunit)
CEQ50_12275	COG0525	valine-tRNA ligase activity
CEQ50_12280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEQ50_12285	COG0564	pseudouridine synthase activity
CEQ50_12295	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEQ50_12305	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CEQ50_12320	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CEQ50_12325	COG0251	oxidation-reduction process
CEQ50_12340	COG0204	Acyl-transferase
CEQ50_12345	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEQ50_12350	COG5007	Belongs to the BolA IbaG family
CEQ50_12360	COG2854	intermembrane phospholipid transfer
CEQ50_12365	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CEQ50_12370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CEQ50_12375	COG1127	ABC transporter
CEQ50_12385	COG0517	IMP dehydrogenase activity
CEQ50_12385	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CEQ50_12390	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CEQ50_12400	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CEQ50_12405	COG1137	ATPase activity
CEQ50_12415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEQ50_12420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_12430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_12435	COG2239	Acts as a magnesium transporter
CEQ50_12440	COG0312	modulator of DNA gyrase
CEQ50_12445	COG3028	Belongs to the UPF0307 family
CEQ50_12450	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CEQ50_12455	COG1178	ABC-type Fe3 transport system permease component
CEQ50_12460	COG4143	(ABC) transporter
CEQ50_12465	COG0163	prenyltransferase activity
CEQ50_12470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEQ50_12475	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CEQ50_12480	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CEQ50_12490	COG2105	PFAM AIG2 family protein
CEQ50_12495	COG2911	Protein conserved in bacteria
CEQ50_12500	COG0729	surface antigen
CEQ50_12505	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ50_12510	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CEQ50_12525	COG1136	(ABC) transporter
CEQ50_12545	COG0529	Catalyzes the synthesis of activated sulfate
CEQ50_12550	COG2895	sulfate adenylyltransferase (ATP) activity
CEQ50_12555	COG0175	sulfate reduction
CEQ50_12560	COG1648	precorrin-2 dehydrogenase activity
CEQ50_12560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEQ50_12565	COG0737	Belongs to the 5'-nucleotidase family
CEQ50_12605	COG0513	Belongs to the DEAD box helicase family
CEQ50_12610	COG2153	protein acetylation
CEQ50_12615	COG3266	domain, Protein
CEQ50_12615	COG3061	Opacity-associated protein A
CEQ50_12620	COG0545	Peptidyl-prolyl cis-trans isomerase
CEQ50_12625	COG0203	ribosomal protein L17
CEQ50_12635	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CEQ50_12640	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CEQ50_12645	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEQ50_12655	COG0201	protein transport
CEQ50_12680	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CEQ50_12685	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CEQ50_12705	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CEQ50_12710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CEQ50_12735	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CEQ50_12760	COG0051	transcription antitermination factor activity, RNA binding
CEQ50_12765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEQ50_12770	COG0557	exoribonuclease II activity
CEQ50_12775	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CEQ50_12785	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEQ50_12795	COG1047	Peptidyl-prolyl cis-trans
CEQ50_12800	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CEQ50_12810	COG2249	NAD(P)H dehydrogenase (quinone) activity
CEQ50_12815	COG0488	(ABC) transporter
CEQ50_12825	COG0429	hydrolase of the alpha beta-hydrolase fold
CEQ50_12835	COG3954	Phosphoribulokinase
CEQ50_12840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEQ50_12860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEQ50_12875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEQ50_12885	COG0583	DNA-binding transcription factor activity
CEQ50_12900	COG0180	Tryptophanyl-tRNA synthetase
CEQ50_12905	COG0546	phosphoglycolate phosphatase activity
CEQ50_12910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEQ50_12915	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CEQ50_12930	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CEQ50_12960	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CEQ50_12970	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CEQ50_12970	COG0678	peroxiredoxin activity
CEQ50_12975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEQ50_12985	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CEQ50_12985	COG0165	Argininosuccinate lyase
CEQ50_12995	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEQ50_13000	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CEQ50_13020	COG1045	serine acetyltransferase
CEQ50_13025	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEQ50_13035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEQ50_13040	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CEQ50_13045	COG1053	succinate dehydrogenase
CEQ50_13050	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CEQ50_13055	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CEQ50_13065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEQ50_13070	COG1509	lysine 2,3-aminomutase activity
CEQ50_13085	COG0459	protein refolding
CEQ50_13115	COG0149	triose-phosphate isomerase activity
CEQ50_13120	COG0534	Mate efflux family protein
CEQ50_13125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CEQ50_13130	COG1575	Belongs to the MenA family. Type 1 subfamily
CEQ50_13150	COG1609	Transcriptional regulator
CEQ50_13155	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEQ50_13165	COG0281	malic enzyme
CEQ50_13175	COG0626	cystathionine gamma-synthase activity
CEQ50_13180	COG0460	homoserine dehydrogenase
CEQ50_13180	COG0527	aspartate kinase activity
CEQ50_13185	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CEQ50_13195	COG1494	fructose-1,6-bisphosphatase
CEQ50_13200	COG0205	6-phosphofructokinase activity
CEQ50_13205	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CEQ50_13215	COG0745	RESPONSE REGULATOR receiver
CEQ50_13220	COG2205	protein histidine kinase activity
CEQ50_13225	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CEQ50_13230	COG1278	Cold shock
CEQ50_13235	COG3030	protein affecting phage T7 exclusion by the F plasmid
CEQ50_13240	COG1027	Aspartate ammonia-lyase
CEQ50_13245	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CEQ50_13250	COG1288	antiporter activity
CEQ50_13260	COG0549	Belongs to the carbamate kinase family
CEQ50_13265	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CEQ50_13275	COG0540	Belongs to the ATCase OTCase family
CEQ50_13280	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CEQ50_13285	COG1438	arginine binding
CEQ50_13290	COG4232	protein-disulfide reductase activity
CEQ50_13300	COG3263	regulation of cellular component size
CEQ50_13310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEQ50_13315	COG2205	protein histidine kinase activity
CEQ50_13315	COG0784	Response regulator, receiver
CEQ50_13315	COG2198	Histidine kinase
CEQ50_13320	COG2814	Major facilitator Superfamily
CEQ50_13335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEQ50_13340	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CEQ50_13345	COG0511	ligase activity, forming carbon-carbon bonds
CEQ50_13350	COG0439	Biotin carboxylase
CEQ50_13355	COG2264	protein methyltransferase activity
CEQ50_13360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEQ50_13365	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CEQ50_13370	COG0840	transmembrane signaling receptor activity
CEQ50_13375	COG0789	Transcriptional regulator
CEQ50_13385	COG0151	Belongs to the GarS family
CEQ50_13395	COG0776	regulation of translation
CEQ50_13400	COG1253	flavin adenine dinucleotide binding
CEQ50_13435	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEQ50_13445	COG3068	Protein conserved in bacteria
CEQ50_13450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEQ50_13455	COG0668	transmembrane transport
CEQ50_13460	COG0840	transmembrane signaling receptor activity
CEQ50_13485	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEQ50_13495	COG0438	transferase activity, transferring glycosyl groups
CEQ50_13500	COG0367	asparagine synthase
CEQ50_13510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEQ50_13535	COG1215	transferase activity, transferring glycosyl groups
CEQ50_13550	COG1621	beta-fructofuranosidase activity
CEQ50_13565	COG0022	dehydrogenase e1 component
CEQ50_13570	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CEQ50_13585	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CEQ50_13590	COG1088	dTDP-glucose 4,6-dehydratase activity
CEQ50_13600	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CEQ50_13605	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CEQ50_13625	COG3307	-O-antigen
CEQ50_13635	COG0859	PFAM glycosyl transferase family 9
CEQ50_13650	COG1519	Transferase
CEQ50_13680	COG3642	lipopolysaccharide core region biosynthetic process
CEQ50_13685	COG0859	PFAM glycosyl transferase family 9
CEQ50_13690	COG0463	Glycosyl transferase, family 2
CEQ50_13695	COG0859	PFAM glycosyl transferase family 9
CEQ50_13700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CEQ50_13715	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEQ50_13730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEQ50_13735	COG1309	transcriptional regulator
CEQ50_13740	COG1560	Kdo2-lipid A biosynthetic process
CEQ50_13745	COG1560	Kdo2-lipid A biosynthetic process
CEQ50_13755	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CEQ50_13760	COG1561	YicC-like family, N-terminal region
CEQ50_13765	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CEQ50_13770	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
CEQ50_13775	COG3051	citrate lyase alpha subunit
CEQ50_13780	COG2301	Belongs to the HpcH HpaI aldolase family
CEQ50_13785	COG3052	prosthetic group binding
CEQ50_13790	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CEQ50_13805	COG5016	pyruvate
CEQ50_13805	COG0511	ligase activity, forming carbon-carbon bonds
CEQ50_13810	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CEQ50_13820	COG4565	transcriptional regulatory protein
CEQ50_13835	COG0612	Peptidase, M16
CEQ50_13855	COG1120	ATPase activity
CEQ50_13860	COG4774	siderophore transport
CEQ50_13865	COG1132	(ABC) transporter
CEQ50_13870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ50_13870	COG1263	PTS System
CEQ50_13875	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEQ50_13895	COG0514	ATP-dependent DNA helicase (RecQ)
CEQ50_13900	COG2962	Rard protein
CEQ50_13910	COG1280	lysine exporter protein (LysE YggA)
CEQ50_13920	COG0210	DNA helicase
CEQ50_13925	COG0339	signal peptide processing
CEQ50_13930	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CEQ50_13935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEQ50_13980	COG3501	Rhs element vgr protein
CEQ50_13990	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEQ50_14015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEQ50_14070	COG1309	transcriptional regulator
CEQ50_14075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ50_14080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ50_14085	COG2960	long-chain fatty acid transporting porin activity
CEQ50_14095	COG0583	DNA-binding transcription factor activity
CEQ50_14100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEQ50_14125	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CEQ50_14130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEQ50_14130	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEQ50_14140	COG0084	hydrolase, TatD family'
CEQ50_14145	COG0805	protein transport
CEQ50_14150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEQ50_14160	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CEQ50_14175	COG1322	Protein conserved in bacteria
CEQ50_14195	COG2160	L-arabinose isomerase activity
CEQ50_14205	COG1069	ribulokinase activity
CEQ50_14215	COG1879	ABC-type sugar transport system periplasmic component
CEQ50_14220	COG1129	ABC transporter
CEQ50_14225	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEQ50_14235	COG2081	HI0933 family
CEQ50_14250	COG1528	Iron-storage protein
CEQ50_14255	COG0589	response to stress
CEQ50_14260	COG0697	spore germination
CEQ50_14270	COG0742	ribosomal rna small subunit methyltransferase
CEQ50_14275	COG1522	sequence-specific DNA binding
CEQ50_14295	COG0006	proline dipeptidase activity
CEQ50_14295	COG0006	proline dipeptidase activity
CEQ50_14300	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CEQ50_14310	COG2104	thiamine diphosphate biosynthetic process
CEQ50_14315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEQ50_14320	COG0352	thiamine-phosphate diphosphorylase activity
CEQ50_14400	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CEQ50_14405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEQ50_14410	COG1739	Uncharacterized protein family UPF0029
CEQ50_14420	COG0183	Belongs to the thiolase family
CEQ50_14425	COG0583	DNA-binding transcription factor activity
CEQ50_14430	COG2814	Major facilitator Superfamily
CEQ50_14440	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CEQ50_14445	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEQ50_14450	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEQ50_14455	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEQ50_14460	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEQ50_14465	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEQ50_14475	COG0356	it plays a direct role in the translocation of protons across the membrane
CEQ50_14480	COG3312	ion transport
CEQ50_14485	COG1475	DNA binding
CEQ50_14490	COG1192	Involved in chromosome partitioning
CEQ50_14500	COG0445	tRNA wobble uridine modification
CEQ50_14530	COG2084	Dehydrogenase
CEQ50_14535	COG0814	amino acid
CEQ50_14565	COG0583	DNA-binding transcription factor activity
CEQ50_14570	COG2910	NAD(P)H-binding
CEQ50_14580	COG3304	Inner membrane component domain
CEQ50_14600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEQ50_14605	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CEQ50_14625	COG0363	glucosamine-6-phosphate deaminase activity
CEQ50_14635	COG0739	heme binding
CEQ50_14640	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_14640	COG2213	PTS system mannitol-specific
CEQ50_14645	COG0246	Mannitol dehydrogenase
CEQ50_14650	COG3722	fumarate hydratase activity
CEQ50_14660	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CEQ50_14665	COG1301	dicarboxylic acid transport
CEQ50_14670	COG2259	Doxx family
CEQ50_14695	COG1846	Transcriptional regulator
CEQ50_14705	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CEQ50_14710	COG3046	protein related to deoxyribodipyrimidine photolyase
CEQ50_14715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEQ50_14720	COG0842	Transport permease protein
CEQ50_14725	COG1131	(ABC) transporter
CEQ50_14740	COG3842	ATPase activity
CEQ50_14750	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEQ50_14770	COG0513	Belongs to the DEAD box helicase family
CEQ50_14775	COG0251	oxidation-reduction process
CEQ50_14780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEQ50_14790	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEQ50_14795	COG1328	CTP reductase activity
CEQ50_14805	COG2130	NADP-dependent
CEQ50_14810	COG1309	transcriptional regulator
CEQ50_14825	COG0745	RESPONSE REGULATOR receiver
CEQ50_14835	COG0564	pseudouridine synthase activity
CEQ50_14920	COG3501	Rhs element vgr protein
CEQ50_14975	COG0471	metal ion transport
CEQ50_14980	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CEQ50_14990	COG2188	Transcriptional regulator
CEQ50_14995	COG1131	(ABC) transporter
CEQ50_15005	COG0840	transmembrane signaling receptor activity
CEQ50_15035	COG0671	phosphoesterase, PA-phosphatase related
CEQ50_15040	COG4399	Belongs to the UPF0754 family
CEQ50_15045	COG1132	(ABC) transporter
CEQ50_15065	COG3623	hexulose-6-phosphate isomerase
CEQ50_15070	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CEQ50_15075	COG0561	phosphatase activity
CEQ50_15110	COG4580	involved in the transport of maltose and maltodextrins
CEQ50_15130	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CEQ50_15140	COG1999	signal sequence binding
CEQ50_15155	COG0786	glutamate:sodium symporter activity
CEQ50_15180	COG1566	PFAM secretion protein HlyD family protein
CEQ50_15190	COG3706	GGDEF domain
CEQ50_15205	COG0813	purine-nucleoside phosphorylase activity
CEQ50_15210	COG3272	Protein of unknown function (DUF1722)
CEQ50_15215	COG0789	Transcriptional regulator
CEQ50_15220	COG0415	Belongs to the DNA photolyase family
CEQ50_15225	COG1376	ErfK ybiS ycfS ynhG family protein
CEQ50_15225	COG1388	LysM domain
CEQ50_15235	COG0513	Belongs to the DEAD box helicase family
CEQ50_15265	COG2267	carboxylic ester hydrolase activity
CEQ50_15275	COG0366	Alpha amylase catalytic
CEQ50_15280	COG4989	oxidoreductase activity
CEQ50_15290	COG1136	(ABC) transporter
CEQ50_15290	COG0577	efflux transmembrane transporter activity
CEQ50_15295	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEQ50_15310	COG0745	RESPONSE REGULATOR receiver
CEQ50_15310	COG2972	Histidine kinase
CEQ50_15315	COG3279	Response regulator of the LytR AlgR family
CEQ50_15320	COG2203	Gaf domain
CEQ50_15320	COG3706	GGDEF domain
CEQ50_15320	COG4251	negative regulation of phosphorylation
CEQ50_15320	COG5001	Diguanylate cyclase
CEQ50_15330	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CEQ50_15340	COG3437	response regulator, receiver
CEQ50_15345	COG2205	protein histidine kinase activity
CEQ50_15345	COG4999	Histidine kinase
CEQ50_15345	COG3850	Histidine kinase
CEQ50_15345	COG3437	response regulator, receiver
CEQ50_15355	COG0531	amino acid
CEQ50_15375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEQ50_15385	COG2205	protein histidine kinase activity
CEQ50_15385	COG5002	protein histidine kinase activity
CEQ50_15385	COG0784	Response regulator, receiver
CEQ50_15405	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ50_15415	COG1609	Transcriptional regulator
CEQ50_15420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_15440	COG0673	inositol 2-dehydrogenase activity
CEQ50_15445	COG1765	OsmC-like protein
CEQ50_15450	COG0110	maltose O-acetyltransferase activity
CEQ50_15465	COG0583	DNA-binding transcription factor activity
CEQ50_15475	COG0583	DNA-binding transcription factor activity
CEQ50_15480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEQ50_15485	COG3186	Phenylalanine-4-hydroxylase
CEQ50_15495	COG0840	transmembrane signaling receptor activity
CEQ50_15500	COG0534	Mate efflux family protein
CEQ50_15505	COG2207	Transcriptional regulator
CEQ50_15510	COG0784	Response regulator, receiver
CEQ50_15510	COG3437	response regulator, receiver
CEQ50_15520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ50_15520	COG4191	Histidine kinase
CEQ50_15530	COG2814	Major facilitator Superfamily
CEQ50_15540	COG0443	Heat shock 70 kDa protein
CEQ50_15555	COG3240	lipase activity
CEQ50_15565	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CEQ50_15570	COG5380	lipid catabolic process
CEQ50_15575	COG4412	M6 family metalloprotease domain protein
CEQ50_15575	COG3291	Pkd domain containing protein
CEQ50_15600	COG4607	ABC-type enterochelin transport system periplasmic component
CEQ50_15605	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEQ50_15610	COG4605	iron ion homeostasis
CEQ50_15615	COG4604	ABC transporter, ATP-binding protein
CEQ50_15625	COG3385	transposase activity
CEQ50_15635	COG2153	protein acetylation
CEQ50_15640	COG0697	spore germination
CEQ50_15645	COG0387	Pfam Sodium calcium exchanger
CEQ50_15650	COG0861	Integral membrane protein TerC family
CEQ50_15690	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEQ50_15700	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CEQ50_15720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEQ50_15730	COG3501	Rhs element vgr protein
CEQ50_15800	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ50_15800	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ50_15800	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CEQ50_15805	COG1105	Belongs to the carbohydrate kinase PfkB family
CEQ50_15810	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_15810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_15815	COG1609	Transcriptional regulator
CEQ50_15820	COG0420	3'-5' exonuclease activity
CEQ50_15825	COG0419	ATPase involved in DNA repair
CEQ50_15830	COG2205	protein histidine kinase activity
CEQ50_15830	COG0784	Response regulator, receiver
CEQ50_15835	COG0156	8-amino-7-oxononanoate synthase activity
CEQ50_15845	COG0038	chloride channel
CEQ50_15850	COG0523	cobalamin synthesis protein
CEQ50_15855	COG1136	(ABC) transporter
CEQ50_15860	COG1136	(ABC) transporter
CEQ50_15860	COG0577	efflux transmembrane transporter activity
CEQ50_15865	COG1136	(ABC) transporter
CEQ50_15865	COG0577	efflux transmembrane transporter activity
CEQ50_15880	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CEQ50_15905	COG3730	PTS system glucitol sorbitol-specific
CEQ50_15920	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ50_15925	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_15930	COG1349	DNA-binding transcription factor activity
CEQ50_15935	COG3730	PTS system glucitol sorbitol-specific
CEQ50_15960	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEQ50_15965	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEQ50_15975	COG3005	denitrification pathway
CEQ50_15985	COG0243	molybdopterin cofactor binding
CEQ50_15995	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEQ50_16000	COG3850	Histidine kinase
CEQ50_16005	COG2197	response regulator
CEQ50_16010	COG3069	C4-dicarboxylate transmembrane transporter activity
CEQ50_16035	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEQ50_16045	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CEQ50_16050	COG0513	Belongs to the DEAD box helicase family
CEQ50_16055	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CEQ50_16115	COG5002	protein histidine kinase activity
CEQ50_16175	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CEQ50_16200	COG0384	phenazine biosynthesis protein PhzF
CEQ50_16280	COG2433	Pfam Transposase IS66
CEQ50_16360	COG1335	isochorismatase
CEQ50_16445	COG0653	protein targeting
CEQ50_16470	COG4221	oxidoreductase activity
CEQ50_16475	COG1280	lysine exporter protein (LysE YggA)
CEQ50_16645	COG3041	Addiction module toxin RelE StbE family
CEQ50_16705	COG0110	maltose O-acetyltransferase activity
CEQ50_16915	COG0242	peptide deformylase activity
CEQ50_16935	COG4977	sequence-specific DNA binding
CEQ50_16995	COG0346	lactoylglutathione lyase activity
CEQ50_17005	COG1187	pseudouridine synthase activity
CEQ50_17020	COG0110	maltose O-acetyltransferase activity
CEQ50_17065	COG0724	RNA recognition motif
CEQ50_17080	COG1192	Involved in chromosome partitioning
CEQ50_17100	COG3040	lipid binding
CEQ50_17115	COG2433	Pfam Transposase IS66
CEQ50_17170	COG0653	protein targeting
CEQ50_17230	COG0346	lactoylglutathione lyase activity
CEQ50_17275	COG0724	RNA recognition motif
CEQ50_17365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEQ50_17375	COG0110	maltose O-acetyltransferase activity
CEQ50_17425	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ50_17595	COG0023	Translation Initiation Factor
CEQ50_17610	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEQ50_17620	COG1042	CoA-binding domain protein
CEQ50_17620	COG0045	succinate-CoA ligase (ADP-forming) activity
CEQ50_17620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEQ50_17625	COG0583	DNA-binding transcription factor activity
CEQ50_17645	COG3140	Belongs to the UPF0181 family
CEQ50_17660	COG0745	RESPONSE REGULATOR receiver
CEQ50_17670	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CEQ50_17675	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CEQ50_17690	COG3706	GGDEF domain
CEQ50_17695	COG1278	Cold shock
CEQ50_17705	COG0840	transmembrane signaling receptor activity
CEQ50_17720	COG2501	S4 domain
CEQ50_17725	COG0625	glutathione transferase activity
CEQ50_17740	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CEQ50_17745	COG0488	(ABC) transporter
CEQ50_17760	COG2050	protein possibly involved in aromatic compounds catabolism
CEQ50_17770	COG2824	Alkylphosphonate utilization operon protein PhnA
CEQ50_17780	COG0861	Integral membrane protein TerC family
CEQ50_17785	COG0737	Belongs to the 5'-nucleotidase family
CEQ50_17790	COG3593	DNA synthesis involved in DNA repair
CEQ50_17800	COG0583	DNA-binding transcription factor activity
CEQ50_17805	COG2116	formate transmembrane transporter activity
CEQ50_17825	COG2188	Transcriptional regulator
CEQ50_17830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEQ50_17835	COG1011	Hydrolase
CEQ50_17840	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CEQ50_17850	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CEQ50_17855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEQ50_17860	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CEQ50_17865	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ50_17865	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ50_17870	COG0302	gtp cyclohydrolase
CEQ50_17875	COG0303	'Molybdopterin
CEQ50_17880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEQ50_17885	COG2897	thiosulfate sulfurtransferase activity
CEQ50_17905	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEQ50_17920	COG0545	Peptidyl-prolyl cis-trans isomerase
CEQ50_17925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEQ50_17930	COG0840	transmembrane signaling receptor activity
CEQ50_17935	COG2353	YceI-like domain
CEQ50_17940	COG3038	cytochrome b561
CEQ50_17950	COG2203	Gaf domain
CEQ50_17950	COG4251	negative regulation of phosphorylation
CEQ50_17950	COG3706	GGDEF domain
CEQ50_17950	COG5001	Diguanylate cyclase
CEQ50_17955	COG4172	Belongs to the ABC transporter superfamily
CEQ50_17960	COG4239	(ABC) transporter, permease
CEQ50_17965	COG4174	ABC transporter (Permease)
CEQ50_17970	COG4166	transmembrane transport
CEQ50_17985	COG0189	ligase activity
CEQ50_17985	COG4067	protein conserved in archaea
CEQ50_17995	COG0602	queuosine metabolic process
CEQ50_18000	COG1328	CTP reductase activity
CEQ50_18005	COG3706	GGDEF domain
CEQ50_18030	COG0640	Transcriptional regulator
CEQ50_18050	COG3300	MHYT domain
CEQ50_18050	COG5001	Diguanylate cyclase
CEQ50_18055	COG4191	Histidine kinase
CEQ50_18060	COG3852	Histidine kinase
CEQ50_18070	COG0745	RESPONSE REGULATOR receiver
CEQ50_18085	COG2203	Gaf domain
CEQ50_18085	COG5001	Diguanylate cyclase
CEQ50_18085	COG4251	negative regulation of phosphorylation
CEQ50_18085	COG3706	GGDEF domain
CEQ50_18095	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CEQ50_18100	COG4149	molybdate abc transporter
CEQ50_18105	COG0725	ABC transporter, periplasmic molybdate-binding protein
CEQ50_18110	COG1492	cobalamin metabolic process
CEQ50_18115	COG3111	PFAM Bacterial OB fold (BOF) protein
CEQ50_18125	COG5001	Diguanylate cyclase
CEQ50_18125	COG5002	protein histidine kinase activity
CEQ50_18125	COG3447	MASE1 domain protein
CEQ50_18130	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEQ50_18140	COG2207	Transcriptional regulator
CEQ50_18145	COG1979	alcohol dehydrogenase
CEQ50_18160	COG1840	ABC-type Fe3 transport system, periplasmic component
CEQ50_18170	COG2271	Major facilitator Superfamily
CEQ50_18175	COG0469	pyruvate kinase activity
CEQ50_18180	COG2198	Histidine kinase
CEQ50_18180	COG2205	protein histidine kinase activity
CEQ50_18180	COG0784	Response regulator, receiver
CEQ50_18185	COG1879	ABC-type sugar transport system periplasmic component
CEQ50_18190	COG1803	Methylglyoxal synthase
CEQ50_18195	COG0210	DNA helicase
CEQ50_18200	COG1289	transmembrane transporter activity
CEQ50_18230	COG0784	Response regulator, receiver
CEQ50_18230	COG5002	protein histidine kinase activity
CEQ50_18245	COG2827	Endonuclease containing a URI domain
CEQ50_18270	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEQ50_18275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEQ50_18280	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CEQ50_18285	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CEQ50_18290	COG0247	lactate metabolic process
CEQ50_18295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEQ50_18300	COG3118	belongs to the thioredoxin family
CEQ50_18320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEQ50_18335	COG2146	nitrite reductase [NAD(P)H] activity
CEQ50_18340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEQ50_18360	COG2433	Pfam Transposase IS66
CEQ50_18400	COG4176	ABC-type proline glycine betaine transport system permease component
CEQ50_18405	COG4175	Glycine betaine
CEQ50_18405	COG0517	IMP dehydrogenase activity
CEQ50_18420	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CEQ50_18435	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CEQ50_18445	COG0513	Belongs to the DEAD box helicase family
CEQ50_18450	COG0814	amino acid
CEQ50_18460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEQ50_18465	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CEQ50_18475	COG1984	allophanate hydrolase subunit 2
CEQ50_18485	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CEQ50_18490	COG4181	ATPase activity
CEQ50_18500	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEQ50_18505	COG5001	Diguanylate cyclase
CEQ50_18505	COG1716	ATPase activity
CEQ50_18515	COG0484	heat shock protein binding
CEQ50_18535	COG3437	response regulator, receiver
CEQ50_18535	COG0784	Response regulator, receiver
CEQ50_18550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ50_18555	COG5001	Diguanylate cyclase
CEQ50_18555	COG3300	MHYT domain
CEQ50_18575	COG0010	Belongs to the arginase family
CEQ50_18580	COG1166	arginine decarboxylase activity
CEQ50_18595	COG4176	ABC-type proline glycine betaine transport system permease component
CEQ50_18600	COG2113	Glycine betaine
CEQ50_18620	COG0527	aspartate kinase activity
CEQ50_18625	COG0662	Cupin 2, conserved barrel domain protein
CEQ50_18630	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CEQ50_18635	COG0456	acetyltransferase
CEQ50_18645	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CEQ50_18685	COG0366	Alpha amylase catalytic
CEQ50_18705	COG0714	Associated with various cellular activities
CEQ50_18725	COG2304	oxidoreductase activity
CEQ50_18740	COG3706	GGDEF domain
CEQ50_18750	COG1403	HNH endonuclease
CEQ50_18755	COG3530	Putative quorum-sensing-regulated virulence factor
CEQ50_18760	COG1368	sulfuric ester hydrolase activity
CEQ50_18770	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEQ50_18775	COG1063	alcohol dehydrogenase
CEQ50_18780	COG0156	8-amino-7-oxononanoate synthase activity
CEQ50_18790	COG0346	lactoylglutathione lyase activity
CEQ50_18805	COG2197	response regulator
CEQ50_18810	COG3851	Histidine kinase
CEQ50_18815	COG2271	Major facilitator Superfamily
CEQ50_18850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEQ50_18855	COG0640	Transcriptional regulator
CEQ50_18860	COG0798	PFAM Bile acid sodium symporter
CEQ50_18865	COG0640	Transcriptional regulator
CEQ50_18870	COG0659	secondary active sulfate transmembrane transporter activity
CEQ50_18875	COG0589	response to stress
CEQ50_18900	COG1917	Cupin 2, conserved barrel domain protein
CEQ50_18900	COG4977	sequence-specific DNA binding
CEQ50_18905	COG4771	TonB-dependent receptor
CEQ50_18910	COG2814	Major facilitator Superfamily
CEQ50_18915	COG2226	methyltransferase
CEQ50_18915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEQ50_18915	COG3433	isochorismatase activity
CEQ50_18940	COG1021	2,3-dihydroxybenzoate-AMP ligase
CEQ50_18945	COG1132	(ABC) transporter
CEQ50_18950	COG1132	(ABC) transporter
CEQ50_18955	COG0516	GMP reductase activity
CEQ50_18960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEQ50_18985	COG1278	Cold shock
CEQ50_18990	COG4681	YaeQ
CEQ50_18995	COG1017	nitric oxide dioxygenase activity
CEQ50_18995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEQ50_19000	COG3604	Transcriptional regulator
CEQ50_19015	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEQ50_19020	COG3217	Mosc domain protein beta barrel domain protein
CEQ50_19020	COG0633	Ferredoxin
CEQ50_19030	COG3385	transposase activity
CEQ50_19035	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEQ50_19040	COG2354	Protein conserved in bacteria
CEQ50_19045	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CEQ50_19065	COG3706	GGDEF domain
CEQ50_19070	COG1349	DNA-binding transcription factor activity
CEQ50_19100	COG1175	transmembrane transport
CEQ50_19115	COG3842	ATPase activity
CEQ50_19125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEQ50_19130	COG0784	Response regulator, receiver
CEQ50_19130	COG0835	chemotaxis
CEQ50_19135	COG2315	Protein conserved in bacteria
CEQ50_19140	COG3706	GGDEF domain
CEQ50_19175	COG5001	Diguanylate cyclase
CEQ50_19185	COG1741	Belongs to the pirin family
CEQ50_19195	COG3123	guanosine phosphorylase activity
CEQ50_19205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEQ50_19215	COG0765	amino acid transport
CEQ50_19220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ50_19225	COG0765	amino acid transport
CEQ50_19230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEQ50_19250	COG0179	Fumarylacetoacetate (FAA) hydrolase
CEQ50_19260	COG0697	spore germination
CEQ50_19280	COG2814	Major facilitator Superfamily
CEQ50_19285	COG0583	DNA-binding transcription factor activity
CEQ50_19290	COG5001	Diguanylate cyclase
CEQ50_19295	COG0739	heme binding
CEQ50_19305	COG0659	secondary active sulfate transmembrane transporter activity
CEQ50_19325	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEQ50_19330	COG0581	inorganic phosphate transmembrane transporter activity
CEQ50_19335	COG0573	inorganic phosphate transmembrane transporter activity
CEQ50_19340	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEQ50_19350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEQ50_19355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEQ50_19370	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CEQ50_19380	COG0393	Putative heavy-metal-binding
CEQ50_19390	COG3047	cAMP biosynthetic process
CEQ50_19400	COG3397	chitin binding
CEQ50_19405	COG2271	Major facilitator Superfamily
CEQ50_19410	COG0584	glycerophosphoryl diester phosphodiesterase
CEQ50_19420	COG3527	Alpha-acetolactate decarboxylase
CEQ50_19445	COG0640	Transcriptional regulator
CEQ50_19450	COG0583	DNA-binding transcription factor activity
CEQ50_19455	COG1620	l-lactate permease
CEQ50_19460	COG1304	FMN binding
CEQ50_19475	COG1881	PFAM PEBP family protein
CEQ50_19490	COG1230	cation diffusion facilitator family transporter
CEQ50_19495	COG3122	Protein conserved in bacteria
CEQ50_19505	COG3568	Endonuclease Exonuclease Phosphatase
CEQ50_19540	COG0583	DNA-binding transcription factor activity
CEQ50_19550	COG1609	Transcriptional regulator
CEQ50_19555	COG1472	Belongs to the glycosyl hydrolase 3 family
CEQ50_19560	COG3842	ATPase activity
CEQ50_19565	COG0395	ABC-type sugar transport system, permease component
CEQ50_19570	COG1175	transmembrane transport
CEQ50_19580	COG1609	Transcriptional regulator
CEQ50_19585	COG4580	involved in the transport of maltose and maltodextrins
CEQ50_19605	COG2211	Major facilitator Superfamily
CEQ50_19615	COG1067	ATP-dependent peptidase activity
CEQ50_19625	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CEQ50_19630	COG0363	glucosamine-6-phosphate deaminase activity
CEQ50_19640	COG0583	DNA-binding transcription factor activity
CEQ50_19655	COG1609	Transcriptional regulator
CEQ50_19660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ50_19665	COG1879	ABC-type sugar transport system periplasmic component
CEQ50_19670	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEQ50_19675	COG1129	ABC transporter
CEQ50_19680	COG1869	D-ribose catabolic process
CEQ50_19695	COG3501	Rhs element vgr protein
CEQ50_19705	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CEQ50_19710	COG1640	4-alpha-glucanotransferase
CEQ50_19715	COG0058	SHG alpha-glucan phosphorylase activity
CEQ50_19720	COG2909	trisaccharide binding
CEQ50_19745	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEQ50_19765	COG0840	transmembrane signaling receptor activity
CEQ50_19800	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CEQ50_19810	COG0259	pyridoxamine-phosphate oxidase activity
CEQ50_19840	COG3706	GGDEF domain
CEQ50_19840	COG0745	RESPONSE REGULATOR receiver
CEQ50_19860	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CEQ50_19865	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CEQ50_19870	COG0840	transmembrane signaling receptor activity
CEQ50_19880	COG0835	chemotaxis
CEQ50_19885	COG0643	Histidine kinase
CEQ50_19885	COG2198	Histidine kinase
CEQ50_19900	COG1444	tRNA N-acetyltransferase activity
CEQ50_19905	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine