locus-tag	class	description
CEJ46_00005	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEJ46_00015	COG0706	membrane insertase activity
CEJ46_00020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CEJ46_00035	COG1126	abc transporter atp-binding protein
CEJ46_00055	COG0592	DNA-directed DNA polymerase activity
CEJ46_00060	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEJ46_00065	COG0187	DNA topoisomerase II activity
CEJ46_00080	COG0071	Belongs to the small heat shock protein (HSP20) family
CEJ46_00085	COG3977	Valine--pyruvate aminotransferase
CEJ46_00095	COG0752	glycyl-tRNA synthetase alpha subunit
CEJ46_00100	COG2119	membrane
CEJ46_00125	COG0604	alcohol dehydrogenase
CEJ46_00135	COG0129	dihydroxy-acid dehydratase activity
CEJ46_00140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEJ46_00145	COG3978	acetolactate synthase activity
CEJ46_00155	COG0606	chelatase, subunit chli
CEJ46_00180	COG0840	transmembrane signaling receptor activity
CEJ46_00185	COG0840	transmembrane signaling receptor activity
CEJ46_00195	COG3335	DDE superfamily endonuclease
CEJ46_00215	COG3344	reverse transcriptase
CEJ46_00225	COG0606	chelatase, subunit chli
CEJ46_00235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEJ46_00240	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CEJ46_00255	COG3084	Protein conserved in bacteria
CEJ46_00265	COG1272	protein, Hemolysin III
CEJ46_00275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEJ46_00280	COG0569	domain protein
CEJ46_00285	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEJ46_00285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEJ46_00290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEJ46_00295	COG0242	peptide deformylase activity
CEJ46_00300	COG1652	LysM domain
CEJ46_00305	COG0758	DNA mediated transformation
CEJ46_00310	COG2922	Belongs to the Smg family
CEJ46_00315	COG0551	DNA topoisomerase type I activity
CEJ46_00325	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CEJ46_00330	COG0009	L-threonylcarbamoyladenylate synthase
CEJ46_00335	COG0408	coproporphyrinogen oxidase activity
CEJ46_00340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CEJ46_00350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CEJ46_00390	COG1943	Transposase
CEJ46_00395	COG3071	HemY protein
CEJ46_00400	COG2959	enzyme of heme biosynthesis
CEJ46_00405	COG1587	Uroporphyrinogen-III synthase
CEJ46_00415	COG3072	Adenylate cyclase
CEJ46_00430	COG0019	diaminopimelate decarboxylase activity
CEJ46_00445	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CEJ46_00450	COG1011	Hydrolase
CEJ46_00465	COG0561	phosphatase activity
CEJ46_00470	COG2267	carboxylic ester hydrolase activity
CEJ46_00475	COG1280	lysine exporter protein (LysE YggA)
CEJ46_00480	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CEJ46_00485	COG0783	Belongs to the Dps family
CEJ46_00515	COG2095	MarC family integral membrane protein
CEJ46_00525	COG0742	ribosomal rna small subunit methyltransferase
CEJ46_00530	COG0552	protein localization to endoplasmic reticulum
CEJ46_00535	COG2884	Cell division ATP-binding protein ftsE
CEJ46_00540	COG2177	Part of the ABC transporter FtsEX involved in
CEJ46_00545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEJ46_00555	COG0705	Rhomboid family
CEJ46_00560	COG1580	Controls the rotational direction of flagella during chemotaxis
CEJ46_00565	COG3161	chorismate lyase activity
CEJ46_00575	COG2937	Belongs to the GPAT DAPAT family
CEJ46_00590	COG0534	Mate efflux family protein
CEJ46_00610	COG3250	beta-galactosidase activity
CEJ46_00635	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CEJ46_00710	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CEJ46_00715	COG3300	MHYT domain
CEJ46_00715	COG5001	Diguanylate cyclase
CEJ46_00725	COG3852	Histidine kinase
CEJ46_00735	COG0174	glutamine synthetase
CEJ46_00750	COG1490	D-aminoacyl-tRNA deacylase activity
CEJ46_00755	COG0456	acetyltransferase
CEJ46_00765	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CEJ46_00770	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CEJ46_00775	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CEJ46_00780	COG3031	protein transport across the cell outer membrane
CEJ46_00790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEJ46_00795	COG1459	type II secretion system
CEJ46_00800	COG2165	general secretion pathway protein
CEJ46_00805	COG2165	general secretion pathway protein
CEJ46_00810	COG2165	general secretion pathway protein
CEJ46_00815	COG4795	General secretion pathway protein
CEJ46_00820	COG3156	type II secretion system protein K
CEJ46_00825	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CEJ46_00830	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CEJ46_00840	COG1218	3'(2'),5'-bisphosphate nucleotidase
CEJ46_00845	COG0494	nUDIX hydrolase
CEJ46_00850	COG0316	Belongs to the HesB IscA family
CEJ46_00850	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CEJ46_00855	COG1040	competence protein
CEJ46_00860	COG0596	Alpha beta hydrolase
CEJ46_00870	COG2183	response to ionizing radiation
CEJ46_00875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEJ46_00895	COG0583	DNA-binding transcription factor activity
CEJ46_00915	COG0745	RESPONSE REGULATOR receiver
CEJ46_00925	COG2233	PERMEase
CEJ46_00930	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CEJ46_00935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEJ46_00940	COG1758	RNA polymerase activity
CEJ46_00945	COG0194	GDP metabolic process
CEJ46_00950	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CEJ46_00955	COG0248	Ppx GppA phosphatase
CEJ46_00965	COG3118	belongs to the thioredoxin family
CEJ46_00970	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CEJ46_00980	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CEJ46_01030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEJ46_01040	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEJ46_01045	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CEJ46_01045	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CEJ46_01050	COG1072	(Pantothenic acid kinase))
CEJ46_01075	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEJ46_01080	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEJ46_01085	COG0250	Participates in transcription elongation, termination and antitermination
CEJ46_01095	COG0081	regulation of translation
CEJ46_01100	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CEJ46_01105	COG0222	ribosome binding
CEJ46_01110	COG0085	RNA polymerase activity
CEJ46_01115	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CEJ46_01120	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CEJ46_01125	COG2816	NAD+ diphosphatase activity
CEJ46_01145	COG4942	peptidase
CEJ46_01150	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CEJ46_01165	COG0490	domain, Protein
CEJ46_01165	COG0471	metal ion transport
CEJ46_01175	COG1162	GTPase activity
CEJ46_01180	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CEJ46_01230	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CEJ46_01235	COG0802	atpase or kinase
CEJ46_01240	COG0860	N-Acetylmuramoyl-L-alanine amidase
CEJ46_01245	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CEJ46_01250	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CEJ46_01255	COG1923	regulation of RNA biosynthetic process
CEJ46_01260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEJ46_01265	COG0330	HflC and HflK could
CEJ46_01270	COG0330	HflC and HflK could
CEJ46_01275	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CEJ46_01290	COG0545	Peptidyl-prolyl cis-trans isomerase
CEJ46_01295	COG2964	Protein conserved in bacteria
CEJ46_01300	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CEJ46_01305	COG2923	Belongs to the DsrF TusC family
CEJ46_01320	COG0049	tRNA binding
CEJ46_01325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEJ46_01330	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEJ46_01335	COG0360	Binds together with S18 to 16S ribosomal RNA
CEJ46_01340	COG2965	DNA replication, synthesis of RNA primer
CEJ46_01350	COG0359	binds to the 23S rRNA
CEJ46_01360	COG0305	Participates in initiation and elongation during chromosome replication
CEJ46_01365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEJ46_01370	COG0166	Belongs to the GPI family
CEJ46_01380	COG0735	belongs to the Fur family
CEJ46_01385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEJ46_01405	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEJ46_01415	COG0175	sulfate reduction
CEJ46_01500	COG1410	methionine synthase
CEJ46_01500	COG0646	methionine synthase
CEJ46_01505	COG0527	aspartate kinase activity
CEJ46_01510	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CEJ46_01525	COG2239	Acts as a magnesium transporter
CEJ46_01535	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEJ46_01550	COG0629	single-stranded DNA binding
CEJ46_01555	COG2200	EAL domain
CEJ46_01555	COG2199	diguanylate cyclase activity
CEJ46_01580	COG3267	Type II secretory pathway component ExeA
CEJ46_01580	COG3409	Peptidoglycan-binding domain 1 protein
CEJ46_01590	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEJ46_01595	COG1459	type II secretion system
CEJ46_01640	COG1077	Cell shape determining protein MreB Mrl
CEJ46_01645	COG1792	Involved in formation and maintenance of cell shape
CEJ46_01650	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CEJ46_01655	COG0424	maF-like protein
CEJ46_01660	COG1530	ribonuclease E activity
CEJ46_01665	COG3164	Protein of unknown function
CEJ46_01670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEJ46_01675	COG0312	modulator of DNA gyrase
CEJ46_01680	COG2235	arginine
CEJ46_01715	COG3335	DDE superfamily endonuclease
CEJ46_01750	COG3039	Transposase
CEJ46_01755	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEJ46_01770	COG0589	response to stress
CEJ46_01800	COG0531	amino acid
CEJ46_01805	COG0142	geranyltranstransferase activity
CEJ46_01820	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CEJ46_01825	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEJ46_01830	COG2966	Psort location CytoplasmicMembrane, score
CEJ46_01835	COG3610	response to peptide
CEJ46_01850	COG2967	ApaG domain
CEJ46_01860	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CEJ46_01865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEJ46_01870	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CEJ46_01875	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CEJ46_01925	COG0741	lytic transglycosylase activity
CEJ46_01980	COG2313	pseudouridylate synthase activity
CEJ46_01990	COG1846	Transcriptional regulator
CEJ46_01995	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEJ46_02000	COG0697	spore germination
CEJ46_02010	COG1942	4-Oxalocrotonate Tautomerase
CEJ46_02015	COG0546	phosphoglycolate phosphatase activity
CEJ46_02025	COG1194	a g-specific adenine glycosylase
CEJ46_02030	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CEJ46_02035	COG2066	Belongs to the glutaminase family
CEJ46_02040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEJ46_02055	COG1872	DUF167
CEJ46_02060	COG0762	integral membrane protein
CEJ46_02065	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CEJ46_02070	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CEJ46_02090	COG1678	Uncharacterized ACR, COG1678
CEJ46_02100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEJ46_02105	COG2356	endonuclease I
CEJ46_02110	COG3091	SprT-like family
CEJ46_02115	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CEJ46_02120	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEJ46_02125	COG0583	DNA-binding transcription factor activity
CEJ46_02130	COG4771	TonB-dependent receptor
CEJ46_02135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEJ46_02140	COG0126	phosphoglycerate kinase activity
CEJ46_02150	COG0191	fructose-bisphosphate aldolase activity
CEJ46_02155	COG0668	transmembrane transport
CEJ46_02175	COG3706	GGDEF domain
CEJ46_02180	COG0469	pyruvate kinase activity
CEJ46_02185	COG1349	DNA-binding transcription factor activity
CEJ46_02195	COG2131	deaminase
CEJ46_02270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEJ46_02270	COG4191	Histidine kinase
CEJ46_02295	COG3501	Rhs element vgr protein
CEJ46_02360	COG0328	RNA-DNA hybrid ribonuclease activity
CEJ46_02380	COG1280	lysine exporter protein (LysE YggA)
CEJ46_02445	COG2003	Belongs to the UPF0758 family
CEJ46_02460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEJ46_02470	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CEJ46_02485	COG0582	viral genome integration into host DNA
CEJ46_02495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEJ46_02500	COG0358	DNA primase activity
CEJ46_02505	COG1610	YqeY-like protein
CEJ46_02525	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CEJ46_02530	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CEJ46_02535	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEJ46_02540	COG1968	undecaprenyl-diphosphatase activity
CEJ46_02545	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CEJ46_02550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CEJ46_02555	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CEJ46_02560	COG0585	pseudouridine synthase activity
CEJ46_02565	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CEJ46_02570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CEJ46_02575	COG4942	peptidase
CEJ46_02575	COG1388	LysM domain
CEJ46_02580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEJ46_02585	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEJ46_02605	COG4208	sulfate ABC transporter
CEJ46_02610	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CEJ46_02615	COG1546	Belongs to the CinA family
CEJ46_02620	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CEJ46_02625	COG2137	regulation of response to DNA damage stimulus
CEJ46_02630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEJ46_02635	COG0527	aspartate kinase activity
CEJ46_02690	COG5016	pyruvate
CEJ46_02690	COG0511	ligase activity, forming carbon-carbon bonds
CEJ46_02695	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CEJ46_02705	COG1238	metal cluster binding
CEJ46_02710	COG0612	Peptidase, M16
CEJ46_02725	COG4536	flavin adenine dinucleotide binding
CEJ46_02730	COG4137	Cytochrome C assembly protein
CEJ46_02735	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEJ46_02755	COG0335	large ribosomal subunit rRNA binding
CEJ46_02760	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CEJ46_02765	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CEJ46_02770	COG0237	dephospho-CoA kinase activity
CEJ46_02780	COG1459	type II secretion system
CEJ46_02785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEJ46_02795	COG0157	Belongs to the NadC ModD family
CEJ46_02805	COG0716	FMN binding
CEJ46_02810	COG4974	Belongs to the 'phage' integrase family
CEJ46_02815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEJ46_02820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CEJ46_02825	COG2186	Transcriptional regulator
CEJ46_02830	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CEJ46_02835	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEJ46_02840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEJ46_02855	COG0288	reversible hydration of carbon dioxide
CEJ46_02860	COG0659	secondary active sulfate transmembrane transporter activity
CEJ46_02865	COG1131	(ABC) transporter
CEJ46_02870	COG0842	Transport permease protein
CEJ46_02885	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CEJ46_02895	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEJ46_02905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEJ46_02910	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CEJ46_02915	COG1489	DNA binding
CEJ46_02920	COG1643	Atp-dependent helicase
CEJ46_02925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEJ46_02930	COG1752	Esterase of the alpha-beta hydrolase superfamily
CEJ46_02935	COG1049	propionate catabolic process, 2-methylcitrate cycle
CEJ46_02940	COG1929	Belongs to the glycerate kinase type-1 family
CEJ46_02945	COG2610	gluconate transmembrane transporter activity
CEJ46_02950	COG3835	regulator
CEJ46_02965	COG0004	ammonium transporteR
CEJ46_02970	COG1840	ABC-type Fe3 transport system, periplasmic component
CEJ46_02980	COG3842	ATPase activity
CEJ46_02985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEJ46_03000	COG2971	BadF BadG BcrA BcrD
CEJ46_03010	COG4608	Belongs to the ABC transporter superfamily
CEJ46_03015	COG0444	Belongs to the ABC transporter superfamily
CEJ46_03020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEJ46_03045	COG0628	permease
CEJ46_03050	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEJ46_03055	COG0316	Belongs to the HesB IscA family
CEJ46_03070	COG0739	heme binding
CEJ46_03075	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CEJ46_03085	COG2239	Acts as a magnesium transporter
CEJ46_03090	COG2027	D-alanyl-D-alanine carboxypeptidase
CEJ46_03100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEJ46_03105	COG1534	Rna-binding protein
CEJ46_03115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEJ46_03120	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CEJ46_03125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEJ46_03130	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEJ46_03145	COG0779	Required for maturation of 30S ribosomal subunits
CEJ46_03150	COG0195	Participates in both transcription termination and antitermination
CEJ46_03165	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CEJ46_03185	COG1846	Transcriptional regulator
CEJ46_03215	COG3153	acetyltransferase
CEJ46_03240	COG0513	Belongs to the DEAD box helicase family
CEJ46_03245	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CEJ46_03260	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CEJ46_03265	COG2204	response regulator
CEJ46_03275	COG0667	Aldo Keto reductase
CEJ46_03280	COG3066	DNA modification
CEJ46_03285	COG0494	nUDIX hydrolase
CEJ46_03290	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CEJ46_03295	COG0730	response to heat
CEJ46_03305	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEJ46_03310	COG1283	sodium-dependent phosphate transmembrane transporter activity
CEJ46_03315	COG0583	DNA-binding transcription factor activity
CEJ46_03320	COG0640	Transcriptional regulator
CEJ46_03330	COG0728	peptidoglycan biosynthetic process
CEJ46_03335	COG0196	riboflavin kinase activity
CEJ46_03350	COG1047	Peptidyl-prolyl cis-trans
CEJ46_03360	COG1966	Carbon starvation protein
CEJ46_03370	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEJ46_03375	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CEJ46_03380	COG1472	Belongs to the glycosyl hydrolase 3 family
CEJ46_03385	COG3279	Response regulator of the LytR AlgR family
CEJ46_03390	COG3275	phosphorelay sensor kinase activity
CEJ46_03395	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEJ46_03400	COG1605	Chorismate mutase
CEJ46_03400	COG0287	Prephenate dehydrogenase
CEJ46_03410	COG0488	(ABC) transporter
CEJ46_03425	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CEJ46_03430	COG5001	Diguanylate cyclase
CEJ46_03435	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEJ46_03440	COG0077	Prephenate dehydratase
CEJ46_03440	COG1605	Chorismate mutase
CEJ46_03445	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEJ46_03450	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEJ46_03455	COG0564	pseudouridine synthase activity
CEJ46_03465	COG0542	response to heat
CEJ46_03510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEJ46_03525	COG0745	RESPONSE REGULATOR receiver
CEJ46_03530	COG5002	protein histidine kinase activity
CEJ46_03540	COG0248	Ppx GppA phosphatase
CEJ46_03545	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CEJ46_03555	COG0581	inorganic phosphate transmembrane transporter activity
CEJ46_03560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEJ46_03565	COG0704	Plays a role in the regulation of phosphate uptake
CEJ46_03570	COG3142	Participates in the control of copper homeostasis
CEJ46_03575	COG0450	alkyl hydroperoxide reductase
CEJ46_03580	COG0583	DNA-binding transcription factor activity
CEJ46_03585	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CEJ46_03595	COG0517	IMP dehydrogenase activity
CEJ46_03600	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CEJ46_03610	COG1862	Preprotein translocase
CEJ46_03615	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEJ46_03620	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEJ46_03625	COG0483	inositol monophosphate 1-phosphatase activity
CEJ46_03630	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CEJ46_03635	COG1959	2 iron, 2 sulfur cluster binding
CEJ46_03645	COG0822	iron-sulfur transferase activity
CEJ46_03650	COG0316	Belongs to the HesB IscA family
CEJ46_03660	COG0443	Heat shock 70 kDa protein
CEJ46_03665	COG0633	Ferredoxin
CEJ46_03670	COG2975	iron-sulfur cluster assembly
CEJ46_03675	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEJ46_03690	COG1426	Protein conserved in bacteria
CEJ46_03695	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CEJ46_03700	COG0124	histidyl-tRNA synthetase
CEJ46_03705	COG2976	Protein conserved in bacteria
CEJ46_03710	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEJ46_03715	COG1160	GTP binding
CEJ46_03730	COG0517	IMP dehydrogenase activity
CEJ46_03730	COG0516	GMP reductase activity
CEJ46_03735	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEJ46_03735	COG0519	Catalyzes the synthesis of GMP from XMP
CEJ46_03765	COG0351	phosphomethylpyrimidine kinase
CEJ46_03775	COG1584	GPR1 FUN34 yaaH family protein
CEJ46_03780	COG1115	amino acid carrier protein
CEJ46_03785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEJ46_03805	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CEJ46_03810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEJ46_03810	COG3711	transcriptional antiterminator
CEJ46_03825	COG3964	amidohydrolase
CEJ46_03870	COG3335	DDE superfamily endonuclease
CEJ46_03880	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CEJ46_04005	COG2003	Belongs to the UPF0758 family
CEJ46_04030	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEJ46_04035	COG3716	PTS system mannose fructose sorbose family IID component
CEJ46_04040	COG3715	PTS system
CEJ46_04045	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEJ46_04050	COG2222	sugar isomerase
CEJ46_04060	COG1349	DNA-binding transcription factor activity
CEJ46_04065	COG1349	DNA-binding transcription factor activity
CEJ46_04080	COG2003	Belongs to the UPF0758 family
CEJ46_04110	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEJ46_04135	COG0582	viral genome integration into host DNA
CEJ46_04150	COG2867	negative regulation of translational initiation
CEJ46_04155	COG2914	Belongs to the UPF0125 (RnfH) family
CEJ46_04160	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEJ46_04165	COG0497	DNA recombination
CEJ46_04175	COG0814	amino acid
CEJ46_04185	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEJ46_04190	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEJ46_04195	COG0443	Heat shock 70 kDa protein
CEJ46_04200	COG0484	heat shock protein binding
CEJ46_04230	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CEJ46_04235	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CEJ46_04245	COG0583	DNA-binding transcription factor activity
CEJ46_04250	COG0590	tRNA wobble adenosine to inosine editing
CEJ46_04255	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CEJ46_04265	COG0047	phosphoribosylformylglycinamidine synthase activity
CEJ46_04265	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEJ46_04285	COG2979	Protein of unknown function (DUF533)
CEJ46_04290	COG0442	prolyl-tRNA aminoacylation
CEJ46_04295	COG1720	tRNA m6t6A37 methyltransferase activity
CEJ46_04305	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEJ46_04335	COG3098	single-species biofilm formation
CEJ46_04340	COG0564	pseudouridine synthase activity
CEJ46_04345	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEJ46_04350	COG0142	geranyltranstransferase activity
CEJ46_04360	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CEJ46_04370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEJ46_04370	COG0301	tRNA thio-modification
CEJ46_04375	COG0583	DNA-binding transcription factor activity
CEJ46_04380	COG2363	Small membrane protein
CEJ46_04390	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEJ46_04395	COG1611	Belongs to the LOG family
CEJ46_04400	COG3706	GGDEF domain
CEJ46_04420	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CEJ46_04425	COG1464	Belongs to the NlpA lipoprotein family
CEJ46_04430	COG2011	ABC-type metal ion transport system permease component
CEJ46_04435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEJ46_04440	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CEJ46_04450	COG1609	Transcriptional regulator
CEJ46_04455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEJ46_04455	COG1263	PTS System
CEJ46_04460	COG0366	Alpha amylase catalytic
CEJ46_04465	COG0745	RESPONSE REGULATOR receiver
CEJ46_04470	COG2205	protein histidine kinase activity
CEJ46_04505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEJ46_04510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEJ46_04520	COG1943	Transposase
CEJ46_04525	COG3335	DDE superfamily endonuclease
CEJ46_04530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEJ46_04535	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CEJ46_04540	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CEJ46_04580	COG1045	serine acetyltransferase
CEJ46_04590	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CEJ46_04620	COG0489	protein tyrosine kinase activity
CEJ46_04625	COG1596	polysaccharide export
CEJ46_04645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEJ46_04660	COG0321	lipoyl(octanoyl) transferase activity
CEJ46_04665	COG2921	Belongs to the UPF0250 family
CEJ46_04670	COG1686	Belongs to the peptidase S11 family
CEJ46_04675	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CEJ46_04680	COG0772	Belongs to the SEDS family
CEJ46_04685	COG0768	penicillin binding
CEJ46_04690	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CEJ46_04695	COG0799	negative regulation of ribosome biogenesis
CEJ46_04700	COG1466	dna polymerase III delta subunit
CEJ46_04705	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CEJ46_04710	COG0495	leucyl-tRNA aminoacylation
CEJ46_04715	COG2888	peptidyl-tyrosine sulfation
CEJ46_04720	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CEJ46_04725	COG4535	Mg2 and Co2 transporter CorC
CEJ46_04735	COG1702	phosphate starvation-inducible protein PhoH
CEJ46_04740	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEJ46_04745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEJ46_04750	COG2190	(PTS) system
CEJ46_04755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEJ46_04760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEJ46_04765	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CEJ46_04770	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CEJ46_04775	COG3115	cell septum assembly
CEJ46_04795	COG0789	Transcriptional regulator
CEJ46_04805	COG0330	HflC and HflK could
CEJ46_04815	COG3118	belongs to the thioredoxin family
CEJ46_04820	COG1090	epimerase
CEJ46_04825	COG0622	Phosphoesterase
CEJ46_04840	COG3710	Transcriptional regulator
CEJ46_04845	COG0326	Molecular chaperone. Has ATPase activity
CEJ46_04855	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CEJ46_04860	COG3104	oligopeptide transport
CEJ46_04870	COG0367	asparagine synthase
CEJ46_04875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEJ46_04875	COG4651	solute:proton antiporter activity
CEJ46_04880	COG1846	Transcriptional regulator
CEJ46_04880	COG1940	carbohydrate kinase activity
CEJ46_04885	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CEJ46_04890	COG2190	(PTS) system
CEJ46_04890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEJ46_04890	COG1263	PTS System
CEJ46_04895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEJ46_04915	COG0285	dihydrofolate synthase activity
CEJ46_04920	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CEJ46_04925	COG1286	toxin biosynthetic process
CEJ46_04930	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CEJ46_04935	COG2056	Na+-H+ antiporter family
CEJ46_04940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEJ46_04950	COG0346	lactoylglutathione lyase activity
CEJ46_04965	COG0784	Response regulator, receiver
CEJ46_04965	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CEJ46_04980	COG3335	DDE superfamily endonuclease
CEJ46_04990	COG5433	transposase activity
CEJ46_05015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEJ46_05030	COG4658	electron transport chain
CEJ46_05035	COG4656	Part of a membrane complex involved in electron transport
CEJ46_05040	COG2878	Part of a membrane complex involved in electron transport
CEJ46_05045	COG4657	Part of a membrane complex involved in electron transport
CEJ46_05055	COG1629	transport
CEJ46_05055	COG4774	siderophore transport
CEJ46_05060	COG2382	esterase
CEJ46_05080	COG3433	isochorismatase activity
CEJ46_05080	COG1535	isochorismatase
CEJ46_05085	COG1021	2,3-dihydroxybenzoate-AMP ligase
CEJ46_05090	COG1169	isochorismate synthase
CEJ46_05095	COG1028	Short-chain dehydrogenase reductase Sdr
CEJ46_05100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEJ46_05110	COG1902	pentaerythritol trinitrate reductase activity
CEJ46_05120	COG2814	Major facilitator Superfamily
CEJ46_05125	COG1028	Short-chain dehydrogenase reductase Sdr
CEJ46_05140	COG0556	nucleotide-excision repair
CEJ46_05145	COG2204	response regulator
CEJ46_05150	COG2198	Histidine kinase
CEJ46_05155	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CEJ46_05160	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CEJ46_05165	COG0521	Mo-molybdopterin cofactor biosynthetic process
CEJ46_05175	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CEJ46_05180	COG0314	molybdopterin synthase activity
CEJ46_05185	COG2199	diguanylate cyclase activity
CEJ46_05190	COG4109	DRTGG domain
CEJ46_05200	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CEJ46_05210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEJ46_05210	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEJ46_05215	COG0489	protein tyrosine kinase activity
CEJ46_05220	COG0572	uridine kinase
CEJ46_05225	COG2982	Protein involved in outer membrane biogenesis
CEJ46_05230	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CEJ46_05235	COG2067	long-chain fatty acid transport protein
CEJ46_05240	COG2067	long-chain fatty acid transport protein
CEJ46_05250	COG1595	DNA-templated transcription, initiation
CEJ46_05260	COG0183	Belongs to the thiolase family
CEJ46_05265	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEJ46_05265	COG1024	Enoyl-CoA hydratase
CEJ46_05270	COG0778	Nitroreductase
CEJ46_05275	COG0583	DNA-binding transcription factor activity
CEJ46_05280	COG0745	RESPONSE REGULATOR receiver
CEJ46_05290	COG2832	Protein of unknown function (DUF454)
CEJ46_05295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEJ46_05305	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CEJ46_05335	COG2226	methyltransferase
CEJ46_05350	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEJ46_05360	COG3139	Protein of unknown function (DUF1315)
CEJ46_05365	COG0252	asparaginase activity
CEJ46_05370	COG0616	signal peptide processing
CEJ46_05375	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEJ46_05375	COG1902	pentaerythritol trinitrate reductase activity
CEJ46_05380	COG0788	formyltetrahydrofolate deformylase activity
CEJ46_05390	COG1199	ATP-dependent helicase activity
CEJ46_05395	COG1214	PFAM Peptidase M22, glycoprotease
CEJ46_05410	COG0596	Alpha beta hydrolase
CEJ46_05415	COG0318	PFAM AMP-dependent synthetase and ligase
CEJ46_05420	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CEJ46_05430	COG2894	cell division
CEJ46_05440	COG3100	YcgL domain-containing protein
CEJ46_05445	COG2951	lytic endotransglycosylase activity
CEJ46_05450	COG0583	DNA-binding transcription factor activity
CEJ46_05455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEJ46_05480	COG4628	conserved protein (DUF2132)
CEJ46_05495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEJ46_05505	COG0513	Belongs to the DEAD box helicase family
CEJ46_05515	COG1760	l-serine dehydratase
CEJ46_05530	COG0745	RESPONSE REGULATOR receiver
CEJ46_05535	COG2205	protein histidine kinase activity
CEJ46_05540	COG1653	transport
CEJ46_05550	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEJ46_05555	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CEJ46_05560	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEJ46_05580	COG0544	peptidyl-prolyl cis-trans isomerase activity
CEJ46_05595	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CEJ46_05600	COG0776	regulation of translation
CEJ46_05605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEJ46_05610	COG1555	photosystem II stabilization
CEJ46_05615	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CEJ46_05620	COG0539	negative regulation of cytoplasmic translation
CEJ46_05630	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CEJ46_05635	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CEJ46_05650	COG0583	DNA-binding transcription factor activity
CEJ46_05660	COG0686	Belongs to the AlaDH PNT family
CEJ46_05665	COG1522	sequence-specific DNA binding
CEJ46_05670	COG1674	ftsk spoiiie
CEJ46_05680	COG0501	Belongs to the peptidase M48B family
CEJ46_05690	COG0300	oxidoreductase activity
CEJ46_05705	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CEJ46_05715	COG2268	Band 7 protein
CEJ46_05725	COG1032	radical SAM domain protein
CEJ46_05730	COG5640	endopeptidase activity
CEJ46_05750	COG0583	DNA-binding transcription factor activity
CEJ46_05755	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEJ46_05765	COG2350	Protein conserved in bacteria
CEJ46_05770	COG1607	acyl-coa hydrolase
CEJ46_05800	COG0133	tryptophan synthase activity
CEJ46_05805	COG0135	phosphoribosylanthranilate isomerase activity
CEJ46_05805	COG0134	indole-3-glycerol-phosphate synthase activity
CEJ46_05810	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEJ46_05815	COG0512	Glutamine amidotransferase of anthranilate synthase
CEJ46_05820	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CEJ46_05830	COG0613	PHP domain protein
CEJ46_05835	COG0009	L-threonylcarbamoyladenylate synthase
CEJ46_05840	COG1187	pseudouridine synthase activity
CEJ46_05850	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CEJ46_05855	COG4988	ABC transporter
CEJ46_05860	COG0492	ferredoxin-NADP+ reductase activity
CEJ46_05865	COG3706	GGDEF domain
CEJ46_05865	COG0745	RESPONSE REGULATOR receiver
CEJ46_05880	COG2949	membrane
CEJ46_05890	COG0281	malic enzyme
CEJ46_05910	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CEJ46_05920	COG1737	Transcriptional regulator
CEJ46_05925	COG0076	glutamate decarboxylase activity
CEJ46_05935	COG2431	L-lysine efflux transmembrane transporter activity
CEJ46_05945	COG3070	regulator of competence-specific genes
CEJ46_05960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEJ46_05960	COG4191	Histidine kinase
CEJ46_05970	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CEJ46_05975	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CEJ46_05980	COG2915	High frequency lysogenization protein hflD homolog
CEJ46_05985	COG0482	sulfurtransferase activity
CEJ46_05995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEJ46_06000	COG2916	Histone family protein nucleoid-structuring protein H-NS
CEJ46_06005	COG1757	Na H antiporter
CEJ46_06015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEJ46_06020	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEJ46_06025	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CEJ46_06025	COG0131	Imidazoleglycerol-phosphate dehydratase
CEJ46_06030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CEJ46_06035	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CEJ46_06040	COG0107	imidazoleglycerol-phosphate synthase activity
CEJ46_06045	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CEJ46_06045	COG0140	phosphoribosyl-ATP diphosphatase activity
CEJ46_06050	COG1187	pseudouridine synthase activity
CEJ46_06060	COG1278	Cold shock
CEJ46_06065	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CEJ46_06070	COG0542	response to heat
CEJ46_06075	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CEJ46_06080	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CEJ46_06085	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CEJ46_06090	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CEJ46_06100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEJ46_06105	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEJ46_06110	COG0297	glycogen (starch) synthase activity
CEJ46_06130	COG3070	regulator of competence-specific genes
CEJ46_06135	COG1609	Transcriptional regulator
CEJ46_06145	COG0745	RESPONSE REGULATOR receiver
CEJ46_06150	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CEJ46_06155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEJ46_06165	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CEJ46_06170	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CEJ46_06185	COG0189	ligase activity
CEJ46_06185	COG4067	protein conserved in archaea
CEJ46_06190	COG0500	methyltransferase
CEJ46_06200	COG1801	Protein of unknown function DUF72
CEJ46_06205	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CEJ46_06210	COG1435	thymidine kinase activity
CEJ46_06220	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CEJ46_06245	COG2116	formate transmembrane transporter activity
CEJ46_06250	COG4459	periplasmic nitrate reductase
CEJ46_06255	COG3005	denitrification pathway
CEJ46_06260	COG0243	molybdopterin cofactor binding
CEJ46_06270	COG1227	inorganic diphosphatase activity
CEJ46_06290	COG4172	Belongs to the ABC transporter superfamily
CEJ46_06300	COG4171	peptide transport system, permease
CEJ46_06305	COG4168	peptide transport system, permease
CEJ46_06315	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CEJ46_06320	COG1842	Phage shock protein A
CEJ46_06335	COG0519	Catalyzes the synthesis of GMP from XMP
CEJ46_06340	COG0626	cystathionine gamma-synthase activity
CEJ46_06350	COG0733	neurotransmitter:sodium symporter activity
CEJ46_06355	COG0564	pseudouridine synthase activity
CEJ46_06365	COG2200	EAL domain
CEJ46_06370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CEJ46_06375	COG4136	ATPase activity
CEJ46_06380	COG4135	transport system, permease component
CEJ46_06385	COG4134	Bacterial extracellular solute-binding protein
CEJ46_06395	COG3313	Fe-S protein
CEJ46_06405	COG0737	Belongs to the 5'-nucleotidase family
CEJ46_06415	COG0513	Belongs to the DEAD box helicase family
CEJ46_06435	COG2205	protein histidine kinase activity
CEJ46_06450	COG1061	Type III restriction enzyme res subunit
CEJ46_06455	COG1187	pseudouridine synthase activity
CEJ46_06460	COG2814	Major facilitator Superfamily
CEJ46_06470	COG0702	epimerase
CEJ46_06475	COG0534	Mate efflux family protein
CEJ46_06480	COG4181	ATPase activity
CEJ46_06495	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CEJ46_06500	COG5433	transposase activity
CEJ46_06520	COG0019	diaminopimelate decarboxylase activity
CEJ46_06555	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEJ46_06560	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEJ46_06565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEJ46_06575	COG0840	transmembrane signaling receptor activity
CEJ46_06590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEJ46_06590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEJ46_06590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEJ46_06595	COG2207	Transcriptional regulator
CEJ46_06605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEJ46_06615	COG1342	Belongs to the UPF0251 family
CEJ46_06635	COG1129	ABC transporter
CEJ46_06650	COG1902	pentaerythritol trinitrate reductase activity
CEJ46_06655	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEJ46_06660	COG5002	protein histidine kinase activity
CEJ46_06665	COG0745	RESPONSE REGULATOR receiver
CEJ46_06695	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CEJ46_06700	COG0372	Belongs to the citrate synthase family
CEJ46_06705	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CEJ46_06710	COG2828	Protein conserved in bacteria
CEJ46_06730	COG0561	phosphatase activity
CEJ46_06735	COG0602	queuosine metabolic process
CEJ46_06765	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEJ46_06770	COG1254	Belongs to the acylphosphatase family
CEJ46_06775	COG2920	part of a sulfur-relay system
CEJ46_06780	COG0670	Belongs to the BI1 family
CEJ46_06785	COG1126	abc transporter atp-binding protein
CEJ46_06790	COG0765	amino acid transport
CEJ46_06795	COG4597	amino acid ABC transporter
CEJ46_06800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEJ46_06805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEJ46_06805	COG1648	precorrin-2 dehydrogenase activity
CEJ46_06810	COG3706	GGDEF domain
CEJ46_06820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEJ46_06825	COG0574	Belongs to the PEP-utilizing enzyme family
CEJ46_06825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEJ46_06840	COG2996	Protein conserved in bacteria
CEJ46_06850	COG1943	Transposase
CEJ46_06860	COG3008	intermembrane lipid transfer
CEJ46_06865	COG2995	paraquat-inducible protein a
CEJ46_06870	COG1132	(ABC) transporter
CEJ46_06875	COG1956	GAF domain-containing protein
CEJ46_06895	COG0308	aminopeptidase N
CEJ46_06905	COG2902	Dehydrogenase
CEJ46_06910	COG0167	dihydroorotate dehydrogenase activity
CEJ46_06945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEJ46_06950	COG1067	ATP-dependent peptidase activity
CEJ46_06955	COG3120	sequence-specific DNA binding
CEJ46_06975	COG3278	Belongs to the heme-copper respiratory oxidase family
CEJ46_06990	COG2010	Cytochrome c
CEJ46_07000	COG2217	Heavy metal translocating P-type atpase
CEJ46_07015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEJ46_07020	COG0589	response to stress
CEJ46_07045	COG3842	ATPase activity
CEJ46_07050	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEJ46_07055	COG1177	transmembrane transport
CEJ46_07060	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEJ46_07065	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEJ46_07070	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEJ46_07075	COG0004	ammonium transporteR
CEJ46_07080	COG0488	(ABC) transporter
CEJ46_07085	COG2197	response regulator
CEJ46_07095	COG2271	Major facilitator Superfamily
CEJ46_07100	COG1840	ABC-type Fe3 transport system, periplasmic component
CEJ46_07110	COG3842	ATPase activity
CEJ46_07115	COG0746	molybdenum cofactor guanylyltransferase activity
CEJ46_07120	COG1763	Mo-molybdopterin cofactor biosynthetic process
CEJ46_07145	COG0840	transmembrane signaling receptor activity
CEJ46_07150	COG0791	NLP P60 protein
CEJ46_07175	COG1793	dna ligase
CEJ46_07180	COG4667	esterase of the alpha-beta hydrolase superfamily
CEJ46_07195	COG0848	biopolymer transport protein
CEJ46_07200	COG0811	peptide transport
CEJ46_07205	COG0811	peptide transport
CEJ46_07235	COG0625	glutathione transferase activity
CEJ46_07245	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CEJ46_07255	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEJ46_07270	COG1115	amino acid carrier protein
CEJ46_07275	COG1280	lysine exporter protein (LysE YggA)
CEJ46_07280	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CEJ46_07285	COG0477	Major facilitator Superfamily
CEJ46_07290	COG0583	DNA-binding transcription factor activity
CEJ46_07300	COG1643	Atp-dependent helicase
CEJ46_07320	COG3706	GGDEF domain
CEJ46_07335	COG0443	Heat shock 70 kDa protein
CEJ46_07365	COG1609	Transcriptional regulator
CEJ46_07370	COG2723	6-phospho-beta-galactosidase activity
CEJ46_07375	COG0513	Belongs to the DEAD box helicase family
CEJ46_07380	COG0243	molybdopterin cofactor binding
CEJ46_07385	COG3005	denitrification pathway
CEJ46_07390	COG1278	Cold shock
CEJ46_07405	COG4191	Histidine kinase
CEJ46_07405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEJ46_07410	COG0471	metal ion transport
CEJ46_07420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEJ46_07430	COG3706	GGDEF domain
CEJ46_07440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEJ46_07445	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CEJ46_07450	COG3768	UPF0283 membrane protein
CEJ46_07455	COG3106	COG3106 Predicted ATPase
CEJ46_07480	COG0814	amino acid
CEJ46_07485	COG1760	l-serine dehydratase
CEJ46_07495	COG2356	endonuclease I
CEJ46_07500	COG0720	synthase
CEJ46_07505	COG0840	transmembrane signaling receptor activity
CEJ46_07510	COG0017	Asparaginyl-tRNA synthetase
CEJ46_07520	COG2201	protein-glutamate methylesterase activity
CEJ46_07525	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CEJ46_07530	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CEJ46_07535	COG0835	chemotaxis
CEJ46_07545	COG2198	Histidine kinase
CEJ46_07545	COG0643	Histidine kinase
CEJ46_07555	COG0745	RESPONSE REGULATOR receiver
CEJ46_07560	COG0840	transmembrane signaling receptor activity
CEJ46_07565	COG2770	Histidine kinase
CEJ46_07565	COG3437	response regulator, receiver
CEJ46_07570	COG1448	Aminotransferase
CEJ46_07575	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CEJ46_07585	COG0840	transmembrane signaling receptor activity
CEJ46_07590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEJ46_07595	COG1846	Transcriptional regulator
CEJ46_07610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEJ46_07615	COG3108	Peptidase M15
CEJ46_07620	COG2989	Protein conserved in bacteria
CEJ46_07650	COG1940	carbohydrate kinase activity
CEJ46_07660	COG0748	coenzyme F420 binding
CEJ46_07665	COG3721	Heme iron utilization protein
CEJ46_07670	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CEJ46_07675	COG0811	peptide transport
CEJ46_07680	COG0848	biopolymer transport protein
CEJ46_07690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEJ46_07695	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CEJ46_07720	COG1621	beta-fructofuranosidase activity
CEJ46_07730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEJ46_07730	COG1263	PTS System
CEJ46_07735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEJ46_07740	COG2200	EAL domain
CEJ46_07745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEJ46_07750	COG0840	transmembrane signaling receptor activity
CEJ46_07755	COG1294	oxidase, subunit
CEJ46_07760	COG1271	oxidase subunit
CEJ46_07785	COG3220	belongs to the UPF0276 family
CEJ46_07805	COG1294	oxidase, subunit
CEJ46_07815	COG0251	oxidation-reduction process
CEJ46_07835	COG5433	transposase activity
CEJ46_07860	COG2963	transposase activity
CEJ46_07865	COG2801	Transposase and inactivated derivatives
CEJ46_07905	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CEJ46_07910	COG1012	belongs to the aldehyde dehydrogenase family
CEJ46_07960	COG0515	serine threonine protein kinase
CEJ46_07960	COG4991	sh3 domain protein
CEJ46_07960	COG3064	Membrane
CEJ46_07985	COG1716	ATPase activity
CEJ46_08005	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEJ46_08055	COG3501	Rhs element vgr protein
CEJ46_08085	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CEJ46_08110	COG3706	GGDEF domain
CEJ46_08110	COG0745	RESPONSE REGULATOR receiver
CEJ46_08130	COG0784	Response regulator, receiver
CEJ46_08130	COG0835	chemotaxis
CEJ46_08140	COG4565	transcriptional regulatory protein
CEJ46_08145	COG3290	protein histidine kinase activity
CEJ46_08160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEJ46_08185	COG3063	Type IV pilus biogenesis stability protein PilW
CEJ46_08200	COG1451	nucleotide metabolic process
CEJ46_08210	COG0583	DNA-binding transcription factor activity
CEJ46_08235	COG4139	cobalamin transport
CEJ46_08240	COG2988	succinylglutamate desuccinylase activity
CEJ46_08255	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CEJ46_08265	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CEJ46_08265	COG1073	alpha beta
CEJ46_08265	COG3064	Membrane
CEJ46_08270	COG2994	toxin metabolic process
CEJ46_08300	COG0702	epimerase
CEJ46_08310	COG2925	Exonuclease
CEJ46_08320	COG1346	cytolysis
CEJ46_08325	COG0295	cytidine deaminase activity
CEJ46_08330	COG3300	MHYT domain
CEJ46_08330	COG5001	Diguanylate cyclase
CEJ46_08335	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CEJ46_08345	COG0500	methyltransferase
CEJ46_08360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEJ46_08360	COG0072	phenylalanine-tRNA ligase activity
CEJ46_08405	COG0322	excinuclease ABC activity
CEJ46_08410	COG2197	response regulator
CEJ46_08415	COG0417	DNA replication proofreading
CEJ46_08425	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEJ46_08430	COG3099	Belongs to the UPF0263 family
CEJ46_08445	COG1228	amidohydrolase
CEJ46_08450	COG0010	Belongs to the arginase family
CEJ46_08460	COG2986	histidine ammonia-lyase
CEJ46_08475	COG0247	lactate metabolic process
CEJ46_08475	COG0277	FAD linked oxidase domain protein
CEJ46_08505	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEJ46_08510	COG1960	acyl-CoA dehydrogenase activity
CEJ46_08525	COG5433	transposase activity
CEJ46_08545	COG5001	Diguanylate cyclase
CEJ46_08545	COG3300	MHYT domain
CEJ46_08565	COG0784	Response regulator, receiver
CEJ46_08565	COG5002	protein histidine kinase activity
CEJ46_08580	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CEJ46_08585	COG2885	chlorophyll binding
CEJ46_08605	COG0811	peptide transport
CEJ46_08610	COG0824	Thioesterase
CEJ46_08615	COG3790	cyd operon protein YbgE
CEJ46_08620	COG4890	Cyd operon protein YbgT
CEJ46_08625	COG1294	oxidase, subunit
CEJ46_08630	COG1271	oxidase subunit
CEJ46_08635	COG2255	four-way junction helicase activity
CEJ46_08640	COG0632	four-way junction helicase activity
CEJ46_08645	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CEJ46_08650	COG0215	cysteine-tRNA ligase activity
CEJ46_08655	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEJ46_08660	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEJ46_08665	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CEJ46_08670	COG3012	SEC-C Motif Domain Protein
CEJ46_08685	COG1199	ATP-dependent helicase activity
CEJ46_08695	COG3923	Primosomal replication protein n
CEJ46_08705	COG0840	transmembrane signaling receptor activity
CEJ46_08710	COG0708	Exodeoxyribonuclease III
CEJ46_08715	COG4160	amino acid transport
CEJ46_08720	COG4215	(ABC) transporter
CEJ46_08745	COG1882	Formate acetyltransferase
CEJ46_08760	COG3335	DDE superfamily endonuclease
CEJ46_08770	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEJ46_08785	COG2766	serine protein kinase
CEJ46_08790	COG2718	Belongs to the UPF0229 family
CEJ46_08795	COG2719	SpoVR family
CEJ46_08800	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CEJ46_08815	COG1132	(ABC) transporter
CEJ46_08820	COG0658	competence protein
CEJ46_08820	COG2333	competence protein COMEC
CEJ46_08830	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEJ46_08835	COG1136	(ABC) transporter
CEJ46_08840	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEJ46_08850	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEJ46_08865	COG1252	NADH dehydrogenase
CEJ46_08895	COG0537	adenosine 5'-monophosphoramidase activity
CEJ46_08910	COG2186	Transcriptional regulator
CEJ46_08915	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CEJ46_08925	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CEJ46_08930	COG2226	methyltransferase
CEJ46_08945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CEJ46_08955	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEJ46_08960	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CEJ46_08970	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEJ46_08980	COG4120	Belongs to the binding-protein-dependent transport system permease family
CEJ46_08990	COG3092	negative regulation of chromosome organization
CEJ46_08995	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEJ46_09000	COG0857	belongs to the CobB CobQ family
CEJ46_09000	COG0280	phosphate acetyltransferase
CEJ46_09005	COG0435	Glutathione S-transferase
CEJ46_09015	COG0444	Belongs to the ABC transporter superfamily
CEJ46_09020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEJ46_09025	COG0601	transmembrane transport
CEJ46_09065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEJ46_09070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEJ46_09090	COG1215	transferase activity, transferring glycosyl groups
CEJ46_09125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEJ46_09130	COG1028	Short-chain dehydrogenase reductase Sdr
CEJ46_09155	COG3706	GGDEF domain
CEJ46_09165	COG0800	Aldolase
CEJ46_09170	COG2610	gluconate transmembrane transporter activity
CEJ46_09175	COG3265	gluconokinase activity
CEJ46_09180	COG0129	dihydroxy-acid dehydratase activity
CEJ46_09185	COG1609	Transcriptional regulator
CEJ46_09200	COG5002	protein histidine kinase activity
CEJ46_09200	COG3850	Histidine kinase
CEJ46_09210	COG2985	domain, Protein
CEJ46_09225	COG2194	sulfuric ester hydrolase activity
CEJ46_09230	COG0642	Histidine kinase
CEJ46_09235	COG0745	RESPONSE REGULATOR receiver
CEJ46_09245	COG4221	oxidoreductase activity
CEJ46_09255	COG1022	Amp-dependent synthetase and ligase
CEJ46_09295	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CEJ46_09345	COG3706	GGDEF domain
CEJ46_09360	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CEJ46_09365	COG1946	Acyl-CoA thioesterase
CEJ46_09370	COG1522	sequence-specific DNA binding
CEJ46_09405	COG0318	PFAM AMP-dependent synthetase and ligase
CEJ46_09410	COG1441	menaquinone biosynthetic process
CEJ46_09415	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CEJ46_09425	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CEJ46_09430	COG1169	isochorismate synthase
CEJ46_09440	COG0436	Aminotransferase
CEJ46_09445	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CEJ46_09450	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CEJ46_09465	COG0616	signal peptide processing
CEJ46_09470	COG1028	Short-chain dehydrogenase reductase Sdr
CEJ46_09475	COG0835	chemotaxis
CEJ46_09475	COG0784	Response regulator, receiver
CEJ46_09480	COG1940	carbohydrate kinase activity
CEJ46_09490	COG4667	esterase of the alpha-beta hydrolase superfamily
CEJ46_09500	COG0733	neurotransmitter:sodium symporter activity
CEJ46_09510	COG1263	PTS System
CEJ46_09510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEJ46_09515	COG0084	hydrolase, TatD family'
CEJ46_09520	COG0470	DNA polymerase III
CEJ46_09525	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CEJ46_09530	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CEJ46_09535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEJ46_09560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEJ46_09570	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CEJ46_09575	COG1399	metal-binding, possibly nucleic acid-binding protein
CEJ46_09580	COG0424	maF-like protein
CEJ46_09585	COG0564	pseudouridine synthase activity
CEJ46_09590	COG1530	ribonuclease E activity
CEJ46_09600	COG1012	belongs to the aldehyde dehydrogenase family
CEJ46_09600	COG1454	alcohol dehydrogenase
CEJ46_09605	COG2095	MarC family integral membrane protein
CEJ46_09610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEJ46_09615	COG1757	Na H antiporter
CEJ46_09630	COG3082	Protein of unknown function (DUF1414)
CEJ46_09635	COG3083	sulfuric ester hydrolase activity
CEJ46_09645	COG0243	molybdopterin cofactor binding
CEJ46_09650	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CEJ46_09670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEJ46_09675	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CEJ46_09695	COG2853	Lipoprotein
CEJ46_09710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEJ46_09715	COG1138	Cytochrome C-type biogenesis protein
CEJ46_09720	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CEJ46_09730	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEJ46_09735	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEJ46_09740	COG4133	protoheme IX ABC transporter activity
CEJ46_09750	COG0835	chemotaxis
CEJ46_09760	COG1192	Involved in chromosome partitioning
CEJ46_09765	COG2201	protein-glutamate methylesterase activity
CEJ46_09770	COG2198	Histidine kinase
CEJ46_09770	COG0643	Histidine kinase
CEJ46_09775	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CEJ46_09790	COG0455	bacterial-type flagellum organization
CEJ46_09800	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CEJ46_09805	COG2062	phosphohistidine phosphatase, SixA
CEJ46_09810	COG1025	Belongs to the peptidase M16 family
CEJ46_09815	COG3102	Protein conserved in bacteria
CEJ46_09840	COG1918	ferrous iron import across plasma membrane
CEJ46_09845	COG4977	sequence-specific DNA binding
CEJ46_09850	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CEJ46_09855	COG1121	(ABC) transporter
CEJ46_09860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEJ46_09875	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEJ46_09880	COG0567	Dehydrogenase, E1 component
CEJ46_09895	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CEJ46_09900	COG2009	succinate dehydrogenase
CEJ46_09910	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CEJ46_09920	COG0033	Phosphoglucomutase
CEJ46_09925	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CEJ46_09930	COG0596	Alpha beta hydrolase
CEJ46_09940	COG0716	FMN binding
CEJ46_09945	COG1346	cytolysis
CEJ46_09955	COG0583	DNA-binding transcription factor activity
CEJ46_09965	COG0735	belongs to the Fur family
CEJ46_09970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEJ46_09975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEJ46_09980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEJ46_09985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEJ46_09985	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CEJ46_09990	COG0431	NADPH-dependent FMN reductase
CEJ46_10000	COG3101	peptidyl-lysine hydroxylation
CEJ46_10005	COG2860	membrane
CEJ46_10010	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CEJ46_10015	COG2890	protein-(glutamine-N5) methyltransferase activity
CEJ46_10020	COG2840	Smr protein MutS2
CEJ46_10030	COG1684	flagellar biosynthetic protein fliR
CEJ46_10035	COG1987	bacterial-type flagellum assembly
CEJ46_10085	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CEJ46_10095	COG1677	Flagellar hook-basal body complex protein FliE
CEJ46_10100	COG2204	response regulator
CEJ46_10105	COG4191	Histidine kinase
CEJ46_10110	COG2204	response regulator
CEJ46_10115	COG1516	flagellar protein fliS
CEJ46_10125	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CEJ46_10150	COG2837	iron assimilation
CEJ46_10175	COG1393	Belongs to the ArsC family
CEJ46_10180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEJ46_10200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEJ46_10210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEJ46_10215	COG3335	DDE superfamily endonuclease
CEJ46_10225	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEJ46_10245	COG4783	chaperone-mediated protein folding
CEJ46_10250	COG1393	Belongs to the ArsC family
CEJ46_10270	COG2233	PERMEase
CEJ46_10275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEJ46_10285	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CEJ46_10290	COG2912	Transglutaminase-like superfamily
CEJ46_10295	COG3094	Invasion gene expression up-regulator, SirB
CEJ46_10300	COG2890	protein-(glutamine-N5) methyltransferase activity
CEJ46_10305	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CEJ46_10310	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CEJ46_10315	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CEJ46_10330	COG0193	aminoacyl-tRNA hydrolase activity
CEJ46_10435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CEJ46_10445	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEJ46_10445	COG3951	Flagellar rod assembly protein muramidase FlgJ
CEJ46_10450	COG1706	bacterial-type flagellum-dependent cell motility
CEJ46_10455	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CEJ46_10460	COG4786	Flagellar basal body rod
CEJ46_10465	COG4787	bacterial-type flagellum-dependent cell motility
CEJ46_10470	COG1749	Flagellar hook protein flgE
CEJ46_10475	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CEJ46_10480	COG1558	bacterial-type flagellum-dependent cell motility
CEJ46_10485	COG1815	bacterial-type flagellum-dependent cell motility
CEJ46_10495	COG0784	Response regulator, receiver
CEJ46_10495	COG0835	chemotaxis
CEJ46_10505	COG2747	anti-sigma28 factor FlgM
CEJ46_10590	COG3335	DDE superfamily endonuclease
CEJ46_10640	COG2217	Heavy metal translocating P-type atpase
CEJ46_10640	COG2608	mercury ion transmembrane transporter activity
CEJ46_10670	COG1187	pseudouridine synthase activity
CEJ46_10675	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEJ46_10680	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CEJ46_10685	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CEJ46_10690	COG0121	glutamine amidotransferase
CEJ46_10695	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CEJ46_10710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEJ46_10720	COG2226	methyltransferase
CEJ46_10730	COG0741	lytic transglycosylase activity
CEJ46_10730	COG1388	LysM domain
CEJ46_10745	COG0347	Belongs to the P(II) protein family
CEJ46_10755	COG0037	tRNA processing
CEJ46_10760	COG0825	malonyl-CoA metabolic process
CEJ46_10765	COG0587	DNA-directed DNA polymerase activity
CEJ46_10775	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEJ46_10785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEJ46_10790	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEJ46_10795	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CEJ46_10805	COG0750	zinc metalloprotease
CEJ46_10810	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CEJ46_10815	COG0575	Belongs to the CDS family
CEJ46_10820	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CEJ46_10825	COG0233	cytoplasmic translational termination
CEJ46_10835	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CEJ46_10840	COG0052	Belongs to the universal ribosomal protein uS2 family
CEJ46_10845	COG0024	Methionine aminopeptidase
CEJ46_10860	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CEJ46_10865	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CEJ46_10890	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEJ46_10890	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEJ46_10900	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CEJ46_10905	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CEJ46_10925	COG2252	PERMEase
CEJ46_10930	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEJ46_10935	COG0189	ligase activity
CEJ46_10935	COG4067	protein conserved in archaea
CEJ46_10940	COG0189	ligase activity
CEJ46_10950	COG0733	neurotransmitter:sodium symporter activity
CEJ46_10955	COG4251	negative regulation of phosphorylation
CEJ46_10955	COG5001	Diguanylate cyclase
CEJ46_10955	COG2203	Gaf domain
CEJ46_10955	COG3706	GGDEF domain
CEJ46_10960	COG3335	DDE superfamily endonuclease
CEJ46_10970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEJ46_10980	COG1477	protein flavinylation
CEJ46_11015	COG0271	Belongs to the BolA IbaG family
CEJ46_11035	COG2211	Major facilitator Superfamily
CEJ46_11045	COG1595	DNA-templated transcription, initiation
CEJ46_11060	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEJ46_11070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CEJ46_11075	COG2166	iron-sulfur cluster assembly
CEJ46_11080	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CEJ46_11085	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CEJ46_11095	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEJ46_11095	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CEJ46_11105	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEJ46_11110	COG1074	ATP-dependent DNA helicase activity
CEJ46_11115	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CEJ46_11130	COG3141	response to X-ray
CEJ46_11135	COG2171	N-acyltransferase activity
CEJ46_11165	COG1609	Transcriptional regulator
CEJ46_11175	COG1085	galactose-1-phosphate uridylyltransferase
CEJ46_11180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEJ46_11185	COG0534	Mate efflux family protein
CEJ46_11195	COG0784	Response regulator, receiver
CEJ46_11195	COG3437	response regulator, receiver
CEJ46_11200	COG1022	Amp-dependent synthetase and ligase
CEJ46_11205	COG4628	conserved protein (DUF2132)
CEJ46_11210	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEJ46_11215	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CEJ46_11225	COG0560	Phosphoserine phosphatase
CEJ46_11235	COG0813	purine-nucleoside phosphorylase activity
CEJ46_11240	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CEJ46_11250	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CEJ46_11255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEJ46_11260	COG0084	hydrolase, TatD family'
CEJ46_11270	COG1115	amino acid carrier protein
CEJ46_11285	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CEJ46_11290	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CEJ46_11295	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CEJ46_11300	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CEJ46_11305	COG0083	homoserine kinase activity
CEJ46_11320	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CEJ46_11325	COG0745	RESPONSE REGULATOR receiver
CEJ46_11335	COG2198	Histidine kinase
CEJ46_11335	COG5002	protein histidine kinase activity
CEJ46_11335	COG0784	Response regulator, receiver
CEJ46_11340	COG1242	4 iron, 4 sulfur cluster binding
CEJ46_11345	COG0070	glutamate synthase
CEJ46_11345	COG0069	glutamate synthase activity
CEJ46_11345	COG0067	glutamate synthase
CEJ46_11355	COG0067	glutamate synthase
CEJ46_11355	COG0069	glutamate synthase activity
CEJ46_11355	COG0070	glutamate synthase
CEJ46_11360	COG0493	'glutamate synthase
CEJ46_11380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEJ46_11385	COG2860	membrane
CEJ46_11390	COG0583	DNA-binding transcription factor activity
CEJ46_11395	COG0730	response to heat
CEJ46_11405	COG0505	Belongs to the CarA family
CEJ46_11415	COG0494	nUDIX hydrolase
CEJ46_11420	COG0653	protein targeting
CEJ46_11430	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CEJ46_11435	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CEJ46_11440	COG0849	cell division
CEJ46_11445	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CEJ46_11450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEJ46_11455	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CEJ46_11460	COG0772	Belongs to the SEDS family
CEJ46_11465	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CEJ46_11470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEJ46_11475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEJ46_11480	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CEJ46_11485	COG0768	penicillin binding
CEJ46_11490	COG3116	cell division
CEJ46_11505	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CEJ46_11510	COG3107	peptidoglycan biosynthetic process
CEJ46_11520	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CEJ46_11530	COG2969	positive regulation of protein catabolic process
CEJ46_11535	COG0625	glutathione transferase activity
CEJ46_11540	COG2857	Cytochrome c1
CEJ46_11545	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CEJ46_11550	COG0723	plastoquinol--plastocyanin reductase activity
CEJ46_11570	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CEJ46_11575	COG3105	Protein conserved in bacteria
CEJ46_11580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEJ46_11585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEJ46_11590	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CEJ46_11595	COG0187	DNA topoisomerase II activity
CEJ46_11600	COG3150	esterase
CEJ46_11610	COG3151	Protein conserved in bacteria
CEJ46_11615	COG0494	nUDIX hydrolase
CEJ46_11620	COG1538	Outer membrane efflux protein
CEJ46_11630	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CEJ46_11645	COG3025	triphosphatase activity
CEJ46_11650	COG1392	Phosphate transport regulator
CEJ46_11655	COG0306	phosphate transporter
CEJ46_11660	COG4991	sh3 domain protein
CEJ46_11670	COG3409	Peptidoglycan-binding domain 1 protein
CEJ46_11670	COG3267	Type II secretory pathway component ExeA
CEJ46_11675	COG0617	tRNA 3'-terminal CCA addition
CEJ46_11685	COG0504	CTP synthase activity
CEJ46_11690	COG3956	TIGRFAM MazG family protein
CEJ46_11695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEJ46_11700	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEJ46_11705	COG4999	Histidine kinase
CEJ46_11705	COG2205	protein histidine kinase activity
CEJ46_11705	COG3850	Histidine kinase
CEJ46_11705	COG3437	response regulator, receiver
CEJ46_11710	COG0736	holo-[acyl-carrier-protein] synthase activity
CEJ46_11735	COG0681	Belongs to the peptidase S26 family
CEJ46_11740	COG0481	GTPase activity
CEJ46_11745	COG3086	response to oxidative stress
CEJ46_11760	COG1595	DNA-templated transcription, initiation
CEJ46_11765	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CEJ46_11775	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CEJ46_11780	COG0354	folic acid binding
CEJ46_11795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEJ46_11800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEJ46_11810	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CEJ46_11820	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CEJ46_11830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEJ46_11840	COG0028	Belongs to the TPP enzyme family
CEJ46_11845	COG1022	Amp-dependent synthetase and ligase
CEJ46_11865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEJ46_11870	COG0473	3-isopropylmalate dehydrogenase activity
CEJ46_11880	COG0066	3-isopropylmalate dehydratase activity
CEJ46_11945	COG0795	lipopolysaccharide-transporting ATPase activity
CEJ46_11950	COG0795	lipopolysaccharide-transporting ATPase activity
CEJ46_11955	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEJ46_11960	COG2927	DNA polymerase III (CHI subunit)
CEJ46_11965	COG0525	valine-tRNA ligase activity
CEJ46_11970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEJ46_11975	COG0564	pseudouridine synthase activity
CEJ46_11985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEJ46_11995	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CEJ46_12010	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CEJ46_12015	COG0251	oxidation-reduction process
CEJ46_12030	COG0204	Acyl-transferase
CEJ46_12035	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEJ46_12040	COG5007	Belongs to the BolA IbaG family
CEJ46_12050	COG2854	intermembrane phospholipid transfer
CEJ46_12055	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CEJ46_12060	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CEJ46_12065	COG1127	ABC transporter
CEJ46_12075	COG0517	IMP dehydrogenase activity
CEJ46_12075	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CEJ46_12090	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CEJ46_12095	COG1137	ATPase activity
CEJ46_12105	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEJ46_12110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEJ46_12120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEJ46_12125	COG2239	Acts as a magnesium transporter
CEJ46_12130	COG0312	modulator of DNA gyrase
CEJ46_12135	COG3028	Belongs to the UPF0307 family
CEJ46_12140	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CEJ46_12145	COG1178	ABC-type Fe3 transport system permease component
CEJ46_12150	COG4143	(ABC) transporter
CEJ46_12155	COG0163	prenyltransferase activity
CEJ46_12160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEJ46_12165	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CEJ46_12170	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CEJ46_12180	COG2105	PFAM AIG2 family protein
CEJ46_12185	COG2911	Protein conserved in bacteria
CEJ46_12190	COG0729	surface antigen
CEJ46_12195	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEJ46_12200	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CEJ46_12235	COG0529	Catalyzes the synthesis of activated sulfate
CEJ46_12240	COG2895	sulfate adenylyltransferase (ATP) activity
CEJ46_12245	COG0175	sulfate reduction
CEJ46_12250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEJ46_12250	COG1648	precorrin-2 dehydrogenase activity
CEJ46_12255	COG0737	Belongs to the 5'-nucleotidase family
CEJ46_12295	COG0513	Belongs to the DEAD box helicase family
CEJ46_12300	COG2153	protein acetylation
CEJ46_12305	COG3061	Opacity-associated protein A
CEJ46_12305	COG3266	domain, Protein
CEJ46_12310	COG0545	Peptidyl-prolyl cis-trans isomerase
CEJ46_12315	COG0203	ribosomal protein L17
CEJ46_12325	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CEJ46_12330	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CEJ46_12335	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEJ46_12345	COG0201	protein transport
CEJ46_12370	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CEJ46_12375	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CEJ46_12395	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CEJ46_12400	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CEJ46_12425	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CEJ46_12450	COG0051	transcription antitermination factor activity, RNA binding
CEJ46_12455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEJ46_12460	COG0557	exoribonuclease II activity
CEJ46_12465	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CEJ46_12475	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEJ46_12485	COG1047	Peptidyl-prolyl cis-trans
CEJ46_12490	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CEJ46_12500	COG2249	NAD(P)H dehydrogenase (quinone) activity
CEJ46_12505	COG0488	(ABC) transporter
CEJ46_12515	COG0429	hydrolase of the alpha beta-hydrolase fold
CEJ46_12525	COG3954	Phosphoribulokinase
CEJ46_12530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEJ46_12550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEJ46_12565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEJ46_12575	COG0583	DNA-binding transcription factor activity
CEJ46_12590	COG0180	Tryptophanyl-tRNA synthetase
CEJ46_12595	COG0546	phosphoglycolate phosphatase activity
CEJ46_12600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEJ46_12605	COG5433	transposase activity
CEJ46_12610	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CEJ46_12625	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CEJ46_12655	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CEJ46_12665	COG0678	peroxiredoxin activity
CEJ46_12665	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CEJ46_12670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEJ46_12680	COG0165	Argininosuccinate lyase
CEJ46_12680	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CEJ46_12690	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEJ46_12695	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CEJ46_12715	COG1045	serine acetyltransferase
CEJ46_12720	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEJ46_12730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEJ46_12735	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CEJ46_12740	COG1053	succinate dehydrogenase
CEJ46_12745	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CEJ46_12750	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CEJ46_12760	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEJ46_12765	COG1509	lysine 2,3-aminomutase activity
CEJ46_12780	COG0459	protein refolding
CEJ46_12810	COG0149	triose-phosphate isomerase activity
CEJ46_12815	COG0534	Mate efflux family protein
CEJ46_12820	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CEJ46_12825	COG1575	Belongs to the MenA family. Type 1 subfamily
CEJ46_12845	COG1609	Transcriptional regulator
CEJ46_12850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEJ46_12860	COG0281	malic enzyme
CEJ46_12870	COG0626	cystathionine gamma-synthase activity
CEJ46_12875	COG0460	homoserine dehydrogenase
CEJ46_12875	COG0527	aspartate kinase activity
CEJ46_12880	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CEJ46_12890	COG1494	fructose-1,6-bisphosphatase
CEJ46_12895	COG0205	6-phosphofructokinase activity
CEJ46_12900	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CEJ46_12910	COG0745	RESPONSE REGULATOR receiver
CEJ46_12915	COG2205	protein histidine kinase activity
CEJ46_12920	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CEJ46_12925	COG1278	Cold shock
CEJ46_12930	COG3030	protein affecting phage T7 exclusion by the F plasmid
CEJ46_12935	COG1027	Aspartate ammonia-lyase
CEJ46_12940	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CEJ46_12945	COG1288	antiporter activity
CEJ46_12955	COG0549	Belongs to the carbamate kinase family
CEJ46_12960	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CEJ46_12970	COG0540	Belongs to the ATCase OTCase family
CEJ46_12975	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CEJ46_12980	COG1438	arginine binding
CEJ46_12985	COG4232	protein-disulfide reductase activity
CEJ46_12995	COG3263	regulation of cellular component size
CEJ46_13005	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEJ46_13010	COG0784	Response regulator, receiver
CEJ46_13010	COG2198	Histidine kinase
CEJ46_13010	COG2205	protein histidine kinase activity
CEJ46_13015	COG2814	Major facilitator Superfamily
CEJ46_13030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEJ46_13035	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CEJ46_13040	COG0511	ligase activity, forming carbon-carbon bonds
CEJ46_13045	COG0439	Biotin carboxylase
CEJ46_13050	COG2264	protein methyltransferase activity
CEJ46_13055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEJ46_13060	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CEJ46_13065	COG0840	transmembrane signaling receptor activity
CEJ46_13070	COG0789	Transcriptional regulator
CEJ46_13080	COG0151	Belongs to the GarS family
CEJ46_13090	COG0776	regulation of translation
CEJ46_13095	COG1253	flavin adenine dinucleotide binding
CEJ46_13100	COG2852	Protein conserved in bacteria
CEJ46_13110	COG3068	Protein conserved in bacteria
CEJ46_13115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEJ46_13120	COG0668	transmembrane transport
CEJ46_13125	COG0840	transmembrane signaling receptor activity
CEJ46_13130	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CEJ46_13135	COG5433	transposase activity
CEJ46_13140	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEJ46_13145	COG1215	transferase activity, transferring glycosyl groups
CEJ46_13165	COG0463	Glycosyl transferase, family 2
CEJ46_13185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEJ46_13210	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEJ46_13220	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEJ46_13245	COG3754	Rhamnan synthesis protein F
CEJ46_13295	COG0028	Belongs to the TPP enzyme family
CEJ46_13305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEJ46_13325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CEJ46_13355	COG1682	transport, permease protein
CEJ46_13390	COG3307	-O-antigen
CEJ46_13395	COG0859	PFAM glycosyl transferase family 9
CEJ46_13410	COG1519	Transferase
CEJ46_13420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CEJ46_13435	COG3642	lipopolysaccharide core region biosynthetic process
CEJ46_13440	COG0859	PFAM glycosyl transferase family 9
CEJ46_13445	COG0463	Glycosyl transferase, family 2
CEJ46_13450	COG0859	PFAM glycosyl transferase family 9
CEJ46_13455	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CEJ46_13460	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CEJ46_13470	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEJ46_13485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEJ46_13490	COG1309	transcriptional regulator
CEJ46_13495	COG1560	Kdo2-lipid A biosynthetic process
CEJ46_13500	COG1560	Kdo2-lipid A biosynthetic process
CEJ46_13510	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CEJ46_13515	COG1561	YicC-like family, N-terminal region
CEJ46_13530	COG1396	sequence-specific DNA binding
CEJ46_13550	COG0612	Peptidase, M16
CEJ46_13570	COG1120	ATPase activity
CEJ46_13575	COG4774	siderophore transport
CEJ46_13580	COG1132	(ABC) transporter
CEJ46_13585	COG1263	PTS System
CEJ46_13585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEJ46_13590	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEJ46_13610	COG0514	ATP-dependent DNA helicase (RecQ)
CEJ46_13615	COG2962	Rard protein
CEJ46_13620	COG0405	Gamma-glutamyltransferase
CEJ46_13630	COG1280	lysine exporter protein (LysE YggA)
CEJ46_13635	COG0210	DNA helicase
CEJ46_13640	COG0339	signal peptide processing
CEJ46_13645	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CEJ46_13650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEJ46_13675	COG0840	transmembrane signaling receptor activity
CEJ46_13700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEJ46_13755	COG1309	transcriptional regulator
CEJ46_13760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEJ46_13765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEJ46_13770	COG2960	long-chain fatty acid transporting porin activity
CEJ46_13780	COG0583	DNA-binding transcription factor activity
CEJ46_13785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEJ46_13810	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CEJ46_13815	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEJ46_13815	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEJ46_13825	COG0084	hydrolase, TatD family'
CEJ46_13830	COG0805	protein transport
CEJ46_13835	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEJ46_13845	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CEJ46_13855	COG2226	methyltransferase
CEJ46_13860	COG1322	Protein conserved in bacteria
CEJ46_13880	COG2160	L-arabinose isomerase activity
CEJ46_13890	COG1069	ribulokinase activity
CEJ46_13900	COG1879	ABC-type sugar transport system periplasmic component
CEJ46_13905	COG1129	ABC transporter
CEJ46_13910	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEJ46_14000	COG0583	DNA-binding transcription factor activity
CEJ46_14110	COG2081	HI0933 family
CEJ46_14125	COG1528	Iron-storage protein
CEJ46_14130	COG0589	response to stress
CEJ46_14135	COG0697	spore germination
CEJ46_14145	COG0742	ribosomal rna small subunit methyltransferase
CEJ46_14150	COG1522	sequence-specific DNA binding
CEJ46_14170	COG0006	proline dipeptidase activity
CEJ46_14170	COG0006	proline dipeptidase activity
CEJ46_14175	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CEJ46_14185	COG2104	thiamine diphosphate biosynthetic process
CEJ46_14190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEJ46_14195	COG0352	thiamine-phosphate diphosphorylase activity
CEJ46_14285	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CEJ46_14290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEJ46_14295	COG1739	Uncharacterized protein family UPF0029
CEJ46_14305	COG0183	Belongs to the thiolase family
CEJ46_14310	COG0583	DNA-binding transcription factor activity
CEJ46_14315	COG2814	Major facilitator Superfamily
CEJ46_14325	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CEJ46_14330	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEJ46_14335	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEJ46_14340	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEJ46_14345	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEJ46_14350	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEJ46_14360	COG0356	it plays a direct role in the translocation of protons across the membrane
CEJ46_14365	COG3312	ion transport
CEJ46_14370	COG1475	DNA binding
CEJ46_14375	COG1192	Involved in chromosome partitioning
CEJ46_14385	COG0445	tRNA wobble uridine modification
CEJ46_14415	COG2084	Dehydrogenase
CEJ46_14420	COG0814	amino acid
CEJ46_14450	COG0583	DNA-binding transcription factor activity
CEJ46_14455	COG2910	NAD(P)H-binding
CEJ46_14465	COG3304	Inner membrane component domain
CEJ46_14485	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEJ46_14490	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CEJ46_14510	COG0363	glucosamine-6-phosphate deaminase activity
CEJ46_14520	COG0739	heme binding
CEJ46_14525	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEJ46_14525	COG2213	PTS system mannitol-specific
CEJ46_14530	COG0246	Mannitol dehydrogenase
CEJ46_14535	COG3722	fumarate hydratase activity
CEJ46_14545	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CEJ46_14550	COG1301	dicarboxylic acid transport
CEJ46_14555	COG2259	Doxx family
CEJ46_14580	COG1846	Transcriptional regulator
CEJ46_14590	COG3046	protein related to deoxyribodipyrimidine photolyase
CEJ46_14595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEJ46_14600	COG0842	Transport permease protein
CEJ46_14605	COG1131	(ABC) transporter
CEJ46_14620	COG3842	ATPase activity
CEJ46_14630	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEJ46_14650	COG0513	Belongs to the DEAD box helicase family
CEJ46_14655	COG0251	oxidation-reduction process
CEJ46_14660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEJ46_14670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEJ46_14675	COG1328	CTP reductase activity
CEJ46_14685	COG2130	NADP-dependent
CEJ46_14690	COG1309	transcriptional regulator
CEJ46_14705	COG0745	RESPONSE REGULATOR receiver
CEJ46_14715	COG0564	pseudouridine synthase activity
CEJ46_14800	COG3501	Rhs element vgr protein
CEJ46_14850	COG0471	metal ion transport
CEJ46_14855	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CEJ46_14865	COG2188	Transcriptional regulator
CEJ46_14870	COG1131	(ABC) transporter
CEJ46_14880	COG0840	transmembrane signaling receptor activity
CEJ46_14900	COG0671	phosphoesterase, PA-phosphatase related
CEJ46_14905	COG4399	Belongs to the UPF0754 family
CEJ46_14910	COG1132	(ABC) transporter
CEJ46_14930	COG3623	hexulose-6-phosphate isomerase
CEJ46_14935	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CEJ46_14940	COG0561	phosphatase activity
CEJ46_14975	COG4580	involved in the transport of maltose and maltodextrins
CEJ46_14995	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CEJ46_15005	COG1999	signal sequence binding
CEJ46_15020	COG0786	glutamate:sodium symporter activity
CEJ46_15045	COG1566	PFAM secretion protein HlyD family protein
CEJ46_15055	COG3706	GGDEF domain
CEJ46_15070	COG0813	purine-nucleoside phosphorylase activity
CEJ46_15075	COG3272	Protein of unknown function (DUF1722)
CEJ46_15080	COG0789	Transcriptional regulator
CEJ46_15085	COG0415	Belongs to the DNA photolyase family
CEJ46_15090	COG1388	LysM domain
CEJ46_15090	COG1376	ErfK ybiS ycfS ynhG family protein
CEJ46_15100	COG0513	Belongs to the DEAD box helicase family
CEJ46_15110	COG5433	transposase activity
CEJ46_15140	COG2267	carboxylic ester hydrolase activity
CEJ46_15150	COG0366	Alpha amylase catalytic
CEJ46_15155	COG4989	oxidoreductase activity
CEJ46_15165	COG0577	efflux transmembrane transporter activity
CEJ46_15165	COG1136	(ABC) transporter
CEJ46_15170	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEJ46_15185	COG2972	Histidine kinase
CEJ46_15185	COG0745	RESPONSE REGULATOR receiver
CEJ46_15190	COG3279	Response regulator of the LytR AlgR family
CEJ46_15195	COG3706	GGDEF domain
CEJ46_15195	COG2203	Gaf domain
CEJ46_15195	COG5001	Diguanylate cyclase
CEJ46_15195	COG4251	negative regulation of phosphorylation
CEJ46_15205	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CEJ46_15215	COG3437	response regulator, receiver
CEJ46_15220	COG3850	Histidine kinase
CEJ46_15220	COG2205	protein histidine kinase activity
CEJ46_15220	COG3437	response regulator, receiver
CEJ46_15220	COG4999	Histidine kinase
CEJ46_15230	COG0531	amino acid
CEJ46_15250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEJ46_15260	COG0784	Response regulator, receiver
CEJ46_15260	COG2205	protein histidine kinase activity
CEJ46_15260	COG5002	protein histidine kinase activity
CEJ46_15275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEJ46_15280	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEJ46_15295	COG0673	inositol 2-dehydrogenase activity
CEJ46_15300	COG1765	OsmC-like protein
CEJ46_15305	COG0110	maltose O-acetyltransferase activity
CEJ46_15320	COG0583	DNA-binding transcription factor activity
CEJ46_15330	COG0583	DNA-binding transcription factor activity
CEJ46_15335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEJ46_15340	COG3186	Phenylalanine-4-hydroxylase
CEJ46_15355	COG0534	Mate efflux family protein
CEJ46_15360	COG2207	Transcriptional regulator
CEJ46_15365	COG0784	Response regulator, receiver
CEJ46_15365	COG3437	response regulator, receiver
CEJ46_15370	COG4191	Histidine kinase
CEJ46_15370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEJ46_15380	COG2814	Major facilitator Superfamily
CEJ46_15390	COG0443	Heat shock 70 kDa protein
CEJ46_15405	COG3240	lipase activity
CEJ46_15415	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CEJ46_15420	COG5380	lipid catabolic process
CEJ46_15425	COG4412	M6 family metalloprotease domain protein
CEJ46_15425	COG3291	Pkd domain containing protein
CEJ46_15450	COG4607	ABC-type enterochelin transport system periplasmic component
CEJ46_15455	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEJ46_15460	COG4605	iron ion homeostasis
CEJ46_15465	COG4604	ABC transporter, ATP-binding protein
CEJ46_15480	COG2153	protein acetylation
CEJ46_15485	COG0697	spore germination
CEJ46_15490	COG0387	Pfam Sodium calcium exchanger
CEJ46_15495	COG0861	Integral membrane protein TerC family
CEJ46_15505	COG2161	toxin-antitoxin pair type II binding
CEJ46_15530	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CEJ46_15535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEJ46_15575	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEJ46_15585	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CEJ46_15600	COG0612	Peptidase, M16
CEJ46_15615	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CEJ46_15615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEJ46_15615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEJ46_15620	COG1105	Belongs to the carbohydrate kinase PfkB family
CEJ46_15625	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEJ46_15625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEJ46_15630	COG1609	Transcriptional regulator
CEJ46_15635	COG0420	3'-5' exonuclease activity
CEJ46_15640	COG0419	ATPase involved in DNA repair
CEJ46_15645	COG2205	protein histidine kinase activity
CEJ46_15645	COG0784	Response regulator, receiver
CEJ46_15650	COG0156	8-amino-7-oxononanoate synthase activity
CEJ46_15660	COG0038	chloride channel
CEJ46_15665	COG0523	cobalamin synthesis protein
CEJ46_15670	COG1136	(ABC) transporter
CEJ46_15680	COG1136	(ABC) transporter
CEJ46_15680	COG0577	efflux transmembrane transporter activity
CEJ46_15695	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CEJ46_15720	COG5433	transposase activity
CEJ46_15735	COG3730	PTS system glucitol sorbitol-specific
CEJ46_15750	COG1028	Short-chain dehydrogenase reductase Sdr
CEJ46_15755	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEJ46_15760	COG1349	DNA-binding transcription factor activity
CEJ46_15765	COG3730	PTS system glucitol sorbitol-specific
CEJ46_15780	COG3842	ATPase activity
CEJ46_15790	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEJ46_15800	COG2182	Extracellular solute-binding protein
CEJ46_15805	COG1175	transmembrane transport
CEJ46_15810	COG3833	ABC-type maltose transport systems, permease component
CEJ46_15835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEJ46_15840	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEJ46_15850	COG3005	denitrification pathway
CEJ46_15860	COG0243	molybdopterin cofactor binding
CEJ46_15870	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEJ46_15875	COG3850	Histidine kinase
CEJ46_15880	COG2197	response regulator
CEJ46_15885	COG3069	C4-dicarboxylate transmembrane transporter activity
CEJ46_15910	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEJ46_15920	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CEJ46_15925	COG0513	Belongs to the DEAD box helicase family
CEJ46_15930	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CEJ46_16015	COG1028	Short-chain dehydrogenase reductase Sdr
CEJ46_16295	COG3041	Addiction module toxin RelE StbE family
CEJ46_16340	COG0724	RNA recognition motif
CEJ46_16680	COG3040	lipid binding
CEJ46_16685	COG5433	transposase activity
CEJ46_16810	COG0346	lactoylglutathione lyase activity
CEJ46_16825	COG0346	lactoylglutathione lyase activity
CEJ46_16865	COG0583	DNA-binding transcription factor activity
CEJ46_16965	COG3335	DDE superfamily endonuclease
CEJ46_16970	COG5433	transposase activity
CEJ46_17030	COG1028	Short-chain dehydrogenase reductase Sdr
CEJ46_17095	COG5433	transposase activity
CEJ46_17115	COG0023	Translation Initiation Factor
CEJ46_17130	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEJ46_17140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEJ46_17140	COG0045	succinate-CoA ligase (ADP-forming) activity
CEJ46_17140	COG1042	CoA-binding domain protein
CEJ46_17145	COG0583	DNA-binding transcription factor activity
CEJ46_17175	COG3140	Belongs to the UPF0181 family
CEJ46_17190	COG0745	RESPONSE REGULATOR receiver
CEJ46_17200	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CEJ46_17205	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CEJ46_17220	COG3706	GGDEF domain
CEJ46_17225	COG1278	Cold shock
CEJ46_17235	COG0840	transmembrane signaling receptor activity
CEJ46_17250	COG2501	S4 domain
CEJ46_17255	COG0625	glutathione transferase activity
CEJ46_17260	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CEJ46_17265	COG0488	(ABC) transporter
CEJ46_17280	COG2050	protein possibly involved in aromatic compounds catabolism
CEJ46_17290	COG2824	Alkylphosphonate utilization operon protein PhnA
CEJ46_17300	COG0861	Integral membrane protein TerC family
CEJ46_17305	COG0737	Belongs to the 5'-nucleotidase family
CEJ46_17310	COG3593	DNA synthesis involved in DNA repair
CEJ46_17320	COG0583	DNA-binding transcription factor activity
CEJ46_17325	COG2116	formate transmembrane transporter activity
CEJ46_17345	COG2188	Transcriptional regulator
CEJ46_17350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEJ46_17355	COG1011	Hydrolase
CEJ46_17360	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CEJ46_17365	COG5433	transposase activity
CEJ46_17370	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CEJ46_17375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEJ46_17380	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CEJ46_17385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEJ46_17385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEJ46_17390	COG0302	gtp cyclohydrolase
CEJ46_17395	COG0303	'Molybdopterin
CEJ46_17400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEJ46_17405	COG2897	thiosulfate sulfurtransferase activity
CEJ46_17425	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEJ46_17440	COG0545	Peptidyl-prolyl cis-trans isomerase
CEJ46_17445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEJ46_17450	COG0840	transmembrane signaling receptor activity
CEJ46_17455	COG2353	YceI-like domain
CEJ46_17460	COG3038	cytochrome b561
CEJ46_17470	COG4251	negative regulation of phosphorylation
CEJ46_17470	COG3706	GGDEF domain
CEJ46_17470	COG5001	Diguanylate cyclase
CEJ46_17470	COG2203	Gaf domain
CEJ46_17475	COG4172	Belongs to the ABC transporter superfamily
CEJ46_17480	COG4239	(ABC) transporter, permease
CEJ46_17485	COG4174	ABC transporter (Permease)
CEJ46_17490	COG4166	transmembrane transport
CEJ46_17505	COG4067	protein conserved in archaea
CEJ46_17505	COG0189	ligase activity
CEJ46_17515	COG0602	queuosine metabolic process
CEJ46_17520	COG1328	CTP reductase activity
CEJ46_17525	COG3706	GGDEF domain
CEJ46_17530	COG5433	transposase activity
CEJ46_17555	COG0640	Transcriptional regulator
CEJ46_17575	COG3300	MHYT domain
CEJ46_17575	COG5001	Diguanylate cyclase
CEJ46_17580	COG4191	Histidine kinase
CEJ46_17585	COG3852	Histidine kinase
CEJ46_17595	COG0745	RESPONSE REGULATOR receiver
CEJ46_17615	COG3335	DDE superfamily endonuclease
CEJ46_17630	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CEJ46_17635	COG4149	molybdate abc transporter
CEJ46_17640	COG0725	ABC transporter, periplasmic molybdate-binding protein
CEJ46_17645	COG1492	cobalamin metabolic process
CEJ46_17650	COG3111	PFAM Bacterial OB fold (BOF) protein
CEJ46_17660	COG3447	MASE1 domain protein
CEJ46_17660	COG5001	Diguanylate cyclase
CEJ46_17660	COG5002	protein histidine kinase activity
CEJ46_17665	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEJ46_17675	COG2207	Transcriptional regulator
CEJ46_17680	COG1979	alcohol dehydrogenase
CEJ46_17715	COG2198	Histidine kinase
CEJ46_17715	COG2205	protein histidine kinase activity
CEJ46_17715	COG0784	Response regulator, receiver
CEJ46_17720	COG1879	ABC-type sugar transport system periplasmic component
CEJ46_17725	COG1803	Methylglyoxal synthase
CEJ46_17730	COG0210	DNA helicase
CEJ46_17735	COG1289	transmembrane transporter activity
CEJ46_17765	COG5002	protein histidine kinase activity
CEJ46_17765	COG0784	Response regulator, receiver
CEJ46_17780	COG2827	Endonuclease containing a URI domain
CEJ46_17805	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEJ46_17810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEJ46_17815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CEJ46_17820	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CEJ46_17825	COG0247	lactate metabolic process
CEJ46_17830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEJ46_17835	COG3118	belongs to the thioredoxin family
CEJ46_17855	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEJ46_17860	COG1648	precorrin-2 dehydrogenase activity
CEJ46_17860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEJ46_17870	COG2146	nitrite reductase [NAD(P)H] activity
CEJ46_17875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEJ46_17885	COG1335	isochorismatase
CEJ46_17895	COG3335	DDE superfamily endonuclease
CEJ46_17905	COG0697	spore germination
CEJ46_17950	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CEJ46_17965	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CEJ46_17975	COG0513	Belongs to the DEAD box helicase family
CEJ46_17980	COG0814	amino acid
CEJ46_17990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEJ46_17995	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CEJ46_18005	COG1984	allophanate hydrolase subunit 2
CEJ46_18015	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CEJ46_18020	COG4181	ATPase activity
CEJ46_18030	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEJ46_18035	COG5001	Diguanylate cyclase
CEJ46_18035	COG1716	ATPase activity
CEJ46_18045	COG0484	heat shock protein binding
CEJ46_18065	COG0784	Response regulator, receiver
CEJ46_18065	COG3437	response regulator, receiver
CEJ46_18115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEJ46_18120	COG3300	MHYT domain
CEJ46_18120	COG5001	Diguanylate cyclase
CEJ46_18140	COG0010	Belongs to the arginase family
CEJ46_18145	COG1166	arginine decarboxylase activity
CEJ46_18160	COG4176	ABC-type proline glycine betaine transport system permease component
CEJ46_18165	COG2113	Glycine betaine
CEJ46_18185	COG0527	aspartate kinase activity
CEJ46_18190	COG0662	Cupin 2, conserved barrel domain protein
CEJ46_18195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CEJ46_18200	COG0456	acetyltransferase
CEJ46_18210	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CEJ46_18250	COG0366	Alpha amylase catalytic
CEJ46_18270	COG0714	Associated with various cellular activities
CEJ46_18290	COG2304	oxidoreductase activity
CEJ46_18305	COG3706	GGDEF domain
CEJ46_18315	COG1403	HNH endonuclease
CEJ46_18320	COG3530	Putative quorum-sensing-regulated virulence factor
CEJ46_18325	COG1368	sulfuric ester hydrolase activity
CEJ46_18335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEJ46_18340	COG3227	Zinc metalloprotease (Elastase)
CEJ46_18355	COG2258	MOSC domain
CEJ46_18385	COG1063	alcohol dehydrogenase
CEJ46_18390	COG0156	8-amino-7-oxononanoate synthase activity
CEJ46_18400	COG0346	lactoylglutathione lyase activity
CEJ46_18415	COG2197	response regulator
CEJ46_18420	COG3851	Histidine kinase
CEJ46_18425	COG2271	Major facilitator Superfamily
CEJ46_18460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEJ46_18465	COG0640	Transcriptional regulator
CEJ46_18470	COG0798	PFAM Bile acid sodium symporter
CEJ46_18475	COG0640	Transcriptional regulator
CEJ46_18480	COG0659	secondary active sulfate transmembrane transporter activity
CEJ46_18485	COG0589	response to stress
CEJ46_18510	COG4977	sequence-specific DNA binding
CEJ46_18510	COG1917	Cupin 2, conserved barrel domain protein
CEJ46_18515	COG4771	TonB-dependent receptor
CEJ46_18520	COG2814	Major facilitator Superfamily
CEJ46_18525	COG3433	isochorismatase activity
CEJ46_18525	COG2226	methyltransferase
CEJ46_18525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEJ46_18550	COG1021	2,3-dihydroxybenzoate-AMP ligase
CEJ46_18555	COG1132	(ABC) transporter
CEJ46_18560	COG1132	(ABC) transporter
CEJ46_18595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEJ46_18600	COG0745	RESPONSE REGULATOR receiver
CEJ46_18605	COG0642	Histidine kinase
CEJ46_18610	COG2207	Transcriptional regulator
CEJ46_18610	COG4753	response regulator
CEJ46_18650	COG3335	DDE superfamily endonuclease
CEJ46_18665	COG0583	DNA-binding transcription factor activity
CEJ46_18690	COG0714	Associated with various cellular activities
CEJ46_18725	COG1196	nuclear chromosome segregation
CEJ46_18735	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CEJ46_18745	COG2204	response regulator
CEJ46_18800	COG3501	Rhs element vgr protein
CEJ46_18845	COG0516	GMP reductase activity
CEJ46_18850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEJ46_18875	COG1278	Cold shock
CEJ46_18880	COG4681	YaeQ
CEJ46_18885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEJ46_18885	COG1017	nitric oxide dioxygenase activity
CEJ46_18890	COG3604	Transcriptional regulator
CEJ46_18905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEJ46_18910	COG3217	Mosc domain protein beta barrel domain protein
CEJ46_18910	COG0633	Ferredoxin
CEJ46_18920	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEJ46_18925	COG2354	Protein conserved in bacteria
CEJ46_18950	COG3706	GGDEF domain
CEJ46_18955	COG1349	DNA-binding transcription factor activity
CEJ46_18985	COG1175	transmembrane transport
CEJ46_19000	COG3842	ATPase activity
CEJ46_19010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEJ46_19015	COG0835	chemotaxis
CEJ46_19015	COG0784	Response regulator, receiver
CEJ46_19020	COG2315	Protein conserved in bacteria
CEJ46_19025	COG3706	GGDEF domain
CEJ46_19060	COG5001	Diguanylate cyclase
CEJ46_19070	COG1741	Belongs to the pirin family
CEJ46_19080	COG3123	guanosine phosphorylase activity
CEJ46_19090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEJ46_19100	COG0765	amino acid transport
CEJ46_19105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEJ46_19110	COG0765	amino acid transport
CEJ46_19115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEJ46_19130	COG0179	Fumarylacetoacetate (FAA) hydrolase
CEJ46_19140	COG0697	spore germination
CEJ46_19160	COG2814	Major facilitator Superfamily
CEJ46_19165	COG0583	DNA-binding transcription factor activity
CEJ46_19170	COG5001	Diguanylate cyclase
CEJ46_19175	COG0739	heme binding
CEJ46_19185	COG0659	secondary active sulfate transmembrane transporter activity
CEJ46_19205	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEJ46_19210	COG0581	inorganic phosphate transmembrane transporter activity
CEJ46_19215	COG0573	inorganic phosphate transmembrane transporter activity
CEJ46_19220	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEJ46_19230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEJ46_19235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEJ46_19255	COG3047	cAMP biosynthetic process
CEJ46_19265	COG3397	chitin binding
CEJ46_19270	COG2271	Major facilitator Superfamily
CEJ46_19275	COG0584	glycerophosphoryl diester phosphodiesterase
CEJ46_19285	COG3527	Alpha-acetolactate decarboxylase
CEJ46_19300	COG0488	(ABC) transporter
CEJ46_19310	COG3708	Transcriptional regulator
CEJ46_19310	COG2207	Transcriptional regulator
CEJ46_19315	COG0583	DNA-binding transcription factor activity
CEJ46_19320	COG1620	l-lactate permease
CEJ46_19325	COG1304	FMN binding
CEJ46_19340	COG1881	PFAM PEBP family protein
CEJ46_19345	COG3122	Protein conserved in bacteria
CEJ46_19355	COG3568	Endonuclease Exonuclease Phosphatase
CEJ46_19370	COG0840	transmembrane signaling receptor activity
CEJ46_19380	COG1943	Transposase
CEJ46_19385	COG1609	Transcriptional regulator
CEJ46_19390	COG1472	Belongs to the glycosyl hydrolase 3 family
CEJ46_19395	COG3842	ATPase activity
CEJ46_19400	COG0395	ABC-type sugar transport system, permease component
CEJ46_19405	COG1175	transmembrane transport
CEJ46_19415	COG1609	Transcriptional regulator
CEJ46_19420	COG4580	involved in the transport of maltose and maltodextrins
CEJ46_19440	COG2211	Major facilitator Superfamily
CEJ46_19450	COG1067	ATP-dependent peptidase activity
CEJ46_19460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CEJ46_19465	COG0363	glucosamine-6-phosphate deaminase activity
CEJ46_19485	COG1609	Transcriptional regulator
CEJ46_19490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEJ46_19495	COG1879	ABC-type sugar transport system periplasmic component
CEJ46_19500	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEJ46_19505	COG1129	ABC transporter
CEJ46_19510	COG1869	D-ribose catabolic process
CEJ46_19535	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CEJ46_19540	COG1640	4-alpha-glucanotransferase
CEJ46_19545	COG0058	SHG alpha-glucan phosphorylase activity
CEJ46_19550	COG2909	trisaccharide binding
CEJ46_19575	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEJ46_19595	COG0840	transmembrane signaling receptor activity
CEJ46_19630	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CEJ46_19640	COG0259	pyridoxamine-phosphate oxidase activity
CEJ46_19670	COG0745	RESPONSE REGULATOR receiver
CEJ46_19670	COG3706	GGDEF domain
CEJ46_19690	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CEJ46_19695	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CEJ46_19700	COG0840	transmembrane signaling receptor activity
CEJ46_19710	COG0835	chemotaxis
CEJ46_19715	COG2198	Histidine kinase
CEJ46_19715	COG0643	Histidine kinase
CEJ46_19720	COG0745	RESPONSE REGULATOR receiver
CEJ46_19730	COG1444	tRNA N-acetyltransferase activity
CEJ46_19735	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine