locus-tag	class	description
N175_00010	ENOG4107QK7	reductase
N175_00020	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
N175_00030	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
N175_00035	ENOG4105K63	Thioredoxin
N175_00040	ENOG4105C1J	atp-dependent rna helicase
N175_00045	ENOG4105C9X	ppx gppa phosphatase
N175_00050	ENOG4105EX9	Membrane
N175_00060	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
N175_00065	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
N175_00070	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
N175_00075	ENOG4105CB5	ATP-dependent DNA helicase recG
N175_00080	ENOG4105C2W	permease
N175_00085	ENOG4105E0F	Histidine kinase
N175_00090	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
N175_00105	ENOG4108RCM	Nitroreductase
N175_00115	ENOG4105ETT	transcriptional Regulator, LysR family
N175_00125	ENOG4105RA2	Membrane
N175_00140	ENOG4108RRZ	Transcription elongation factor GreB
N175_00145	ENOG4105BZM	domain protein
N175_00155	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
N175_00165	ENOG4105MJ2	Competence protein
N175_00170	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
N175_00175	ENOG4107RK2	ADP-ribose diphosphatase NudE
N175_00180	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
N175_00190	ENOG4105U1E	general secretion pathway protein M
N175_00195	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
N175_00200	ENOG4108RTD	type II secretion system protein K
N175_00205	ENOG4108WWZ	General secretion pathway protein J
N175_00210	ENOG4105X5Z	General secretion pathway protein I
N175_00215	ENOG4105VWV	general secretion pathway protein h
N175_00220	ENOG4108VAU	general secretion pathway protein G
N175_00225	ENOG4105D7Q	type ii secretion system
N175_00230	ENOG4107QHF	type ii secretion system protein e
N175_00240	ENOG4108XKW	General secretion pathway protein C
N175_00245	ENOG4105VEJ	Heat shock protein
N175_00250	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
N175_00260	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
N175_00270	ENOG4105SUU	thioesterase domain
N175_00275	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
N175_00290	ENOG4105C5F	glutamine synthetase
N175_00300	ENOG4105CUX	Signal transduction histidine kinase
N175_00305	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
N175_00310	ENOG4105BZU	Histidine kinase
N175_00315	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
N175_00355	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
N175_00365	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
N175_00400	ENOG4105CAF	HipA N-terminal domain protein
N175_00440	ENOG4108C33	Resolvase
N175_00465	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
N175_00480	ENOG4108Y73	Membrane
N175_00490	ENOG4107R73	Mate efflux family protein
N175_00510	ENOG4105E55	glycerol-3-phosphate acyltransferase
N175_00515	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
N175_00520	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
N175_00525	ENOG4105X6C	Flagellar basal body-associated protein FliL
N175_00530	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
N175_00535	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
N175_00545	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
N175_00550	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
N175_00555	ENOG4105CAK	Cell division ATP-binding protein ftsE
N175_00560	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
N175_00565	ENOG4106H78	methyltransferase
N175_00575	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
N175_00615	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
N175_00645	ENOG4108RMU	ferritin dps family protein
N175_00650	ENOG4105D58	Diguanylate phosphodiesterase
N175_00655	ENOG410829K	Lysine exporter protein (Lyse ygga)
N175_00660	ENOG4108EUD	Lysophospholipase
N175_00665	ENOG4105DQF	Hydrolase
N175_00680	ENOG4106IUH	DTW domain containing protein
N175_00685	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
N175_00690	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
N175_00700	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
N175_00705	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
N175_00715	ENOG4105XQ6	frataxin-like protein
N175_00720	ENOG4107T0K	Adenylate cyclase
N175_00725	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
N175_00730	ENOG41076E6	Uroporphyrinogen-III Synthase
N175_00735	ENOG4105ECF	c-methyltransferase
N175_00740	ENOG410601J	HemY protein
N175_00770	ENOG4108Z0R	Transferase
N175_00775	ENOG4105SG3	Protein of unknown function (DUF1488)
N175_00780	ENOG4105E2X	shikimate dehydrogenase
N175_00785	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
N175_00790	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
N175_00795	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
N175_00800	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
N175_00805	ENOG4108WI1	Dna topoisomerase
N175_00810	ENOG4108RPN	Protein smg homolog
N175_00815	ENOG4105C79	DNA protecting protein DprA
N175_00820	ENOG4108WZM	domain protein
N175_00830	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
N175_00835	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
N175_00840	ENOG4105C1A	potassium transporter peripheral membrane
N175_00845	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
N175_00855	ENOG4108UT2	hemolysin iii
N175_00865	ENOG4105PC1	Conserved Protein
N175_00875	ENOG4105E27	serine threonine protein kinase
N175_00880	ENOG4108Z33	Thiol disulfide Interchange Protein
N175_00965	ENOG4105C0P	Mg chelatase subunit ChlI
N175_00975	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
N175_00980	ENOG4105CM2	brancheD-chain amino acid aminotransferase
N175_00985	ENOG4105C01	Dihydroxy-acid dehydratase
N175_00990	ENOG4105C7B	Threonine dehydratase
N175_00995	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
N175_01010	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
N175_01025	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
N175_01030	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
N175_01035	ENOG4105JKW	Valine--pyruvate aminotransferase
N175_01040	ENOG4108ZNX	Heat shock protein
N175_01055	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
N175_01060	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
N175_01065	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
N175_01070	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
N175_01075	ENOG4105EAB	amino acid AbC transporter
N175_01085	ENOG4105CDA	abc transporter atp-binding protein
N175_01095	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
N175_01100	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
N175_01105	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
N175_01110	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
N175_01115	ENOG4105QTB	Flavodoxin
N175_01120	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
N175_01125	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
N175_01130	ENOG4107QJE	Chromosome Partitioning Protein
N175_01135	ENOG4105FA0	parb-like partition protein
N175_01140	ENOG410684E	atp synthase
N175_01145	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
N175_01150	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
N175_01160	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
N175_01165	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
N175_01170	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
N175_01175	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
N175_01180	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
N175_01185	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
N175_01190	ENOG4105CZQ	inner membrane transport protein YdhC
N175_01195	ENOG4105F52	Transcriptional regulator
N175_01200	ENOG4105CHU	acetyl-coa acetyltransferase
N175_01205	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
N175_01210	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
N175_01215	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
N175_01220	ENOG4108RR8	protoporphyrinogen oxidase
N175_01260	ENOG4105WMR	Protein CrcB homolog
N175_01265	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
N175_01270	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
N175_01275	ENOG4105D06	uba thif-type nad fad binding protein
N175_01280	ENOG4105WHD	thiamine biosynthesis protein ThiS
N175_01285	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
N175_01290	ENOG4105D41	biosynthesis protein thiH
N175_01295	ENOG4105DC7	peptidase M24
N175_01295	ENOG4105DC7	peptidase M24
N175_01300	ENOG4105G2Y	Transcriptional regulator
N175_01305	ENOG4105CNH	Multidrug resistance protein MdtL
N175_01320	ENOG4108VVK	transcriptional Regulator, AsnC
N175_01325	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
N175_01335	ENOG4105EMK	carboxylate amino acid amine transporter
N175_01340	ENOG4108M6U	Universal stress protein A
N175_01345	ENOG41090A1	ferritin
N175_01350	ENOG4108V6B	universal stress protein B
N175_01360	ENOG4105CBX	hi0933 family
N175_01370	ENOG4105CNN	ABC, transporter
N175_01375	ENOG4105C2J	ABC transporter
N175_01380	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
N175_01385	ENOG4105EF1	ribulokinase
N175_01395	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
N175_01415	ENOG4105CGY	Dna recombination protein
N175_01420	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
N175_01425	ENOG4105JC1	sterol-binding domain protein
N175_01430	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
N175_01435	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
N175_01440	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
N175_01445	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
N175_01450	ENOG4105F8V	Hydrolase, tatD family
N175_01455	ENOG4105D52	delta-aminolevulinic acid dehydratase
N175_01460	ENOG4105C2M	dna polymerase I
N175_01465	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
N175_01470	ENOG4106RE7	Cytochrome
N175_01480	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
N175_01485	ENOG4105XCT	Protein of unknown function (DUF2489)
N175_01490	ENOG4105D4P	Coproporphyrinogen iii oxidase
N175_01495	ENOG4105EMY	transcriptional regulator
N175_01500	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
N175_01505	ENOG4105W0Z	cytoplasmic protein
N175_01510	ENOG4105BZS	acriflavin resistance protein
N175_01515	ENOG410624X	efflux transporter, rnd family, mfp subunit
N175_01520	ENOG4107Z3H	Transcriptional regulator, TetR family
N175_01525	ENOG4105C4R	Atp-dependent dna helicase
N175_01530	ENOG4105MPD	Cytochrome
N175_01575	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
N175_01580	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
N175_01595	ENOG4108VYJ	response regulator receiver protein
N175_01655	ENOG4106V8H	Nucleoid-associated protein
N175_01690	ENOG4105DB4	
N175_01730	ENOG4105DC8	reductase
N175_01735	ENOG4105D6S	protein involved in catabolism of external DNA
N175_01740	ENOG4105DGW	oligopeptidase A
N175_01745	ENOG4105C4R	Atp-dependent dna helicase
N175_01765	ENOG4105FR1	rard protein
N175_01770	ENOG4105C9U	ATP-dependent DNA helicase RecQ
N175_01785	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
N175_01790	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N175_01795	ENOG4105C5Y	PTS System
N175_01800	ENOG4105BZ1	(ABC) transporter
N175_01805	ENOG4105E0K	tonB-dependent siderophore receptor
N175_01810	ENOG4105E0A	ABC, transporter
N175_01815	ENOG4105J76	Periplasmic binding protein
N175_01820	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
N175_01840	ENOG4107RAN	Peptidase, M16
N175_01935	ENOG4105DSJ	YicC domain protein
N175_01940	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
N175_01945	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
N175_01950	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
N175_01955	ENOG4105D1S	lipid A biosynthesis
N175_01960	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
N175_01965	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
N175_01975	ENOG4105KDC	50s ribosomal protein l28
N175_01980	ENOG4105W0E	50S ribosomal protein L33
N175_01990	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
N175_01995	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
N175_02000	ENOG4105M5K	heptosyltransferase
N175_02005	ENOG4106WTF	Glycosyl transferase, family 2
N175_02010	ENOG4105DKP	glycosyl transferase, family 9
N175_02015	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
N175_02030	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
N175_02035	ENOG4108UT6	Transferase hexapeptide repeat containing protein
N175_02040	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
N175_02045	ENOG4108ST3	glycosyltransferase
N175_02055	ENOG4105XA0	heptosyltransferase ii
N175_02060	ENOG4105PF3	O-Antigen polymerase
N175_02070	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
N175_02075	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
N175_02080	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
N175_02090	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
N175_02100	ENOG4105EY8	ABC transporter
N175_02110	ENOG410600T	transposase
N175_02115	ENOG410600T	transposase
N175_02135	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
N175_02140	ENOG4105FAW	cDP-glucose 4,6-dehydratase
N175_02145	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
N175_02150	ENOG4105C7K	acetolactate synthase
N175_02160	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
N175_02165	ENOG4105CKK	Glycosyl transferase, family 2
N175_02195	ENOG4106IQQ	
N175_02200	ENOG4105H63	Glycosyl transferase, family 2
N175_02220	ENOG4105D3Q	Sugar transferase
N175_02230	ENOG4105E3R	(LipO)protein
N175_02240	ENOG4108MDC	(LipO)protein
N175_02250	ENOG4105DAY	polysaccharide export protein
N175_02255	ENOG4107ZF2	Phosphatase
N175_02295	ENOG4107T8Q	Glycosyl transferase (Group 1
N175_02310	ENOG4105ESV	Glycosyl transferase, family 4
N175_02315	ENOG4105CY0	Metallo-Beta-Lactamase
N175_02320	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_02325	ENOG4105CUY	Mechanosensitive ion channel
N175_02330	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
N175_02335	ENOG4105R2J	Conserved Protein
N175_02340	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
N175_02355	ENOG4105K70	DNA-binding protein
N175_02370	ENOG4105DC1	bifunctional purine biosynthesis protein purh
N175_02380	ENOG4105W1Y	Transcriptional regulator
N175_02385	ENOG4107U4H	Methyl-accepting chemotaxis
N175_02390	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_02400	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
N175_02405	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
N175_02420	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
N175_02425	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
N175_02430	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
N175_02450	ENOG4105D8G	Major Facilitator superfamily
N175_02455	ENOG4105BZU	Histidine kinase
N175_02460	ENOG4107QN1	sodium solute
N175_02470	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
N175_02480	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
N175_02485	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
N175_02490	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
N175_02495	ENOG4105CXT	aspartate transcarbamylase
N175_02505	ENOG4105DBV	ornithine carbamoyltransferase
N175_02515	ENOG4105CEU	Arginine dihydrolase
N175_02520	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
N175_02525	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
N175_02530	ENOG4108IJ0	Aspartate ammonia-lyase
N175_02535	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
N175_02540	ENOG4105VEQ	Cold shock protein
N175_02545	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
N175_02550	ENOG4105E0F	Histidine kinase
N175_02555	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
N175_02565	ENOG41076HS	cation diffusion facilitator family transporter
N175_02570	ENOG4105CTQ	phosphohexokinase
N175_02575	ENOG4105CBT	Fructose-1,6-bisphosphatase
N175_02580	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
N175_02585	ENOG4105SYT	Methylenetetrahydrofolate reductase
N175_02590	ENOG4105CFH	Aspartokinase
N175_02595	ENOG4105C28	cystathionine
N175_02600	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
N175_02605	ENOG4105C6K	Malic enzyme
N175_02610	ENOG4105VFB	Binds the 23S rRNA (By similarity)
N175_02615	ENOG4105C25	Primosomal protein n'
N175_02620	ENOG4105ETE	Transcriptional regulator (LacI family
N175_02630	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
N175_02635	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
N175_02640	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
N175_02645	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
N175_02650	ENOG4107QMU	Mate efflux family protein
N175_02655	ENOG4105CP7	Triose-phosphate isomerase
N175_02680	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
N175_02685	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
N175_02700	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
N175_02705	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
N175_02710	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
N175_02715	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
N175_02730	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
N175_02735	ENOG4107YZP	Rhodanese domain protein
N175_02740	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
N175_02745	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
N175_02750	ENOG4105D7W	serine acetyltransferase
N175_02760	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
N175_02765	ENOG4105CWC	Acetylornithine deacetylase
N175_02770	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
N175_02775	ENOG4105CAS	nag kinase
N175_02780	ENOG4105CH7	arginosuccinase
N175_02790	ENOG4107QN2	dihydrolipoyl dehydrogenase
N175_02795	ENOG4105EHV	domain protein
N175_02800	ENOG4105C5Q	Transcriptional regulator
N175_02805	ENOG4108JQC	penicillin-binding protein 1A
N175_02830	ENOG4105E4G	Type IV pilus
N175_02835	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
N175_02840	ENOG4105D49	3-dehydroquinate synthase
N175_02850	ENOG4105DFE	Dna adenine methylase
N175_02855	ENOG4105DJV	ribulose-phosphate 3-epimerase
N175_02860	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
N175_02865	ENOG4105C31	Tryptophanyl-tRNA synthetase
N175_02880	ENOG4105CR8	Transcriptional regulator
N175_02900	ENOG4105DDQ	anthranilate synthase
N175_02915	ENOG4105C26	Dehydrogenase
N175_02925	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
N175_02930	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
N175_02935	ENOG4105YP7	UPF0270 protein
N175_02940	ENOG4105DNZ	Alpha Beta Hydrolase
N175_02950	ENOG4105C5H	ABC transporter
N175_02955	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
N175_02965	ENOG4105VKU	nucleicacid-binding protein
N175_02970	ENOG4108YZY	peptidylprolyl cis-trans isomerase
N175_02975	ENOG4105D44	asparaginase
N175_02980	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
N175_02985	ENOG4108UV7	flagellar protein motX
N175_02990	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
N175_02995	ENOG4105C2N	RNA methyltransferase TrmH family group 3
N175_03000	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
N175_03005	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
N175_03010	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
N175_03015	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
N175_03020	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
N175_03025	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
N175_03030	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
N175_03035	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
N175_03040	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
N175_03045	ENOG41083MP	50s ribosomal protein l29
N175_03050	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
N175_03055	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
N175_03065	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
N175_03070	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
N175_03075	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
N175_03080	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
N175_03090	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
N175_03095	ENOG4105VPB	50S ribosomal protein L30
N175_03100	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
N175_03105	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
N175_03115	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
N175_03120	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
N175_03125	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
N175_03130	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
N175_03135	ENOG4108ZT0	50S ribosomal protein l17
N175_03140	ENOG4108V1T	peptidylprolyl cis-trans isomerase
N175_03145	ENOG4108UBT	opacity-associated protein
N175_03150	ENOG4107YB6	acetyltransferase, (GNAT) family
N175_03155	ENOG4105C1J	atp-dependent rna helicase
N175_03195	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
N175_03200	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
N175_03205	ENOG4105C11	sulfate adenylyltransferase), subunit 2
N175_03210	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
N175_03215	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
N175_03250	ENOG4108UUE	Transcriptional regulator
N175_03255	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
N175_03265	ENOG4105CFU	surface antigen
N175_03270	ENOG4105MA0	exported protein
N175_03275	ENOG41066HZ	AIG2-like family
N175_03285	ENOG4105F0N	pyrophosphate phospho-hydrolase
N175_03290	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
N175_03295	ENOG4105DFU	Cell wall formation (By similarity)
N175_03300	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
N175_03305	ENOG4105DP9	ABC transporter
N175_03310	ENOG4106SMU	thiamine transporter membrane protein
N175_03315	ENOG4107T0D	ABC, transporter
N175_03320	ENOG4105N42	UPF0307 protein
N175_03325	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
N175_03330	ENOG4105CJW	magnesium transporter
N175_03335	ENOG41080Z8	PHOSPHOCARRIER protein
N175_03345	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
N175_03350	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
N175_03355	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
N175_03360	ENOG4108IUZ	ABC transporter
N175_03365	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
N175_03375	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
N175_03380	ENOG4105C2X	Arabinose 5-phosphate isomerase
N175_03395	ENOG4105DHJ	ABC, transporter
N175_03400	ENOG4105CY3	ABC transporter, permease
N175_03405	ENOG4107PE3	Mammalian cell entry related domain protein
N175_03410	ENOG4105E3I	toluene tolerance
N175_03420	ENOG4105VFK	BolA family
N175_03425	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
N175_03430	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
N175_03445	ENOG4105KME	endoribonuclease L-psp
N175_03450	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
N175_03455	ENOG4105CXT	aspartate transcarbamylase
N175_03460	ENOG4105DBV	ornithine carbamoyltransferase
N175_03465	ENOG4108IAB	Phoh family
N175_03475	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
N175_03480	ENOG4105K3M	)-transporter
N175_03485	ENOG4105D3G	Pseudouridine synthase
N175_03490	ENOG4105C5I	Dehydrogenase
N175_03495	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
N175_03500	ENOG4105MYG	DNA polymerase iii, chi subunit
N175_03505	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
N175_03510	ENOG4108M8S	permease YjgP YjgQ family protein
N175_03515	ENOG4108K5H	permease YjgP YjgQ family protein
N175_03615	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
N175_03620	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
N175_03630	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
N175_03645	ENOG41064T2	transcriptional regulator, lysR family
N175_03650	ENOG4108IQE	Amp-dependent synthetase and ligase
N175_03655	ENOG4105C7K	acetolactate synthase
N175_03660	ENOG4108ZP8	Acetolactate synthase small subunit
N175_03665	ENOG4108JQ1	Dehydrogenase
N175_03670	ENOG4105E66	phosphoriboisomerase A
N175_03675	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
N175_03680	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
N175_03690	ENOG4105D0A	hydroxylase
N175_03695	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
N175_03710	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
N175_03715	ENOG4105Y75	tpr repeat protein
N175_03725	ENOG4108IYU	L-aspartate oxidase
N175_03730	ENOG4105EMN	RNA polymerase sigma factor
N175_03745	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
N175_03750	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
N175_03755	ENOG4105C3F	Signal peptidase i
N175_03760	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
N175_03765	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
N175_03770	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
N175_03775	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
N175_03780	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
N175_03785	ENOG4105BZU	Histidine kinase
N175_03790	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
N175_03795	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
N175_03800	ENOG4105DXN	mazG family
N175_03805	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
N175_03810	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
N175_03815	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
N175_03830	ENOG4106MWK	domain protein
N175_03835	ENOG4105CJ3	phosphate transporter
N175_03840	ENOG4107IX6	phosphate transport regulator
N175_03850	ENOG4105I7R	Adenylate cyclase
N175_03860	ENOG4108NVR	Methyl-accepting chemotaxis
N175_03865	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
N175_03870	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
N175_03880	ENOG4105DFG	type I secretion outer membrane protein
N175_03885	ENOG41087AY	ADP-Ribose pyrophosphatase
N175_03890	ENOG4108SX3	cytoplasmic protein
N175_03895	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
N175_03900	ENOG4105IPS	esterase
N175_03905	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
N175_03910	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
N175_03915	ENOG4105C0H	protease
N175_03920	ENOG4105C0H	protease
N175_03925	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
N175_03930	ENOG4105D6Z	AFG1 family ATPase
N175_03940	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
N175_03945	ENOG4108UJD	30S ribosomal protein S9
N175_03950	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
N175_03955	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
N175_03960	ENOG4105EIX	cytochrome c1
N175_03965	ENOG4107MKT	Stringent starvation protein a
N175_03970	ENOG4105KB2	stringent starvation protein b
N175_03975	ENOG4105W4M	Transport-associated protein
N175_03980	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
N175_03985	ENOG41082RQ	UPF0102 protein
N175_03990	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
N175_03995	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
N175_04005	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
N175_04010	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
N175_04015	ENOG4105CJN	penicillin-binding protein
N175_04020	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
N175_04025	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
N175_04030	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
N175_04035	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
N175_04045	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
N175_04050	ENOG4105DFU	Cell wall formation (By similarity)
N175_04055	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
N175_04060	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
N175_04065	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
N175_04070	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
N175_04080	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
N175_04085	ENOG4105M6F	mutator MutT protein
N175_04090	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
N175_04100	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
N175_04105	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
N175_04110	ENOG4105EJ9	Membrane
N175_04115	ENOG4105VP0	transcriptional regulator, lysR family
N175_04120	ENOG4105EN6	Membrane
N175_04125	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
N175_04135	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
N175_04150	ENOG4105BZ8	glutamate synthase
N175_04155	ENOG4105CBC	glutamate synthase
N175_04170	ENOG4105N5T	Radical SAM Protein
N175_04175	ENOG4105BZU	Histidine kinase
N175_04185	ENOG41065U4	response regulator
N175_04190	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
N175_04205	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
N175_04210	ENOG4105D98	threonine synthase
N175_04215	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
N175_04220	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
N175_04225	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
N175_04240	ENOG4105BZG	amino acid carrier protein
N175_04250	ENOG4105D1Q	UPF0246 protein
N175_04260	ENOG4105EYA	deoxyribonuclease
N175_04265	ENOG4105D9N	nucleoside
N175_04275	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
N175_04280	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
N175_04285	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
N175_04295	ENOG4105EAC	phosphoserine phosphatase
N175_04305	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
N175_04315	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
N175_04320	ENOG4108IQE	Amp-dependent synthetase and ligase
N175_04325	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
N175_04335	ENOG4105UQX	Mate efflux family protein
N175_04345	ENOG4105CMR	udp-glucose 4-epimerase
N175_04350	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
N175_04355	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
N175_04360	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
N175_04365	ENOG41060NJ	transcriptional regulator
N175_04395	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
N175_04400	ENOG4105X2V	dna damage-inducible protein
N175_04415	ENOG4105DSY	exodeoxyribonuclease V, gamma
N175_04420	ENOG4107QKA	exodeoxyribonuclease V beta
N175_04425	ENOG4107QYX	exodeoxyribonuclease v alpha
N175_04435	ENOG4107QZM	n-acetylglutamate synthase
N175_04445	ENOG4105CA3	membrane-bound lytic murein transglycosylase
N175_04450	ENOG4105CUZ	uba thif-type nad fad binding protein
N175_04455	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
N175_04460	ENOG4105C9B	Cysteine desulfurase
N175_04465	ENOG4107S0N	DJ-1 family
N175_04470	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
N175_04485	ENOG4105K6V	RNA polymerase
N175_04495	ENOG4105EYM	Major Facilitator superfamily
N175_04500	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
N175_04510	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
N175_04515	ENOG4105M85	Bola protein
N175_04520	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
N175_04525	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
N175_04530	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
N175_04535	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
N175_04540	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
N175_04545	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
N175_04550	ENOG4105CJ2	(LipO)protein
N175_04560	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
N175_04580	ENOG4105C8J	)-transporter
N175_04590	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
N175_04595	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
N175_04600	ENOG4105CIN	aminoacyl-histidine dipeptidase
N175_04610	ENOG4105C7N	Xanthine uracil vitamin C permease
N175_04615	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
N175_04620	ENOG4108DJV	Fermentation respiration switch protein
N175_04625	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
N175_04630	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
N175_04635	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
N175_04640	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
N175_04645	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
N175_04660	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
N175_04665	ENOG4107YIM	Involved in the transcription termination process (By similarity)
N175_04670	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
N175_04675	ENOG4108ZAI	phosphatidylglycerophosphatase a
N175_04680	ENOG4108T8E	UPF0325 protein
N175_04685	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
N175_04690	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
N175_04695	ENOG4105CE9	30S ribosomal protein S2
N175_04700	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
N175_04705	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
N175_04710	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
N175_04715	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
N175_04720	ENOG4105KNE	Phosphatidate cytidylyltransferase
N175_04725	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
N175_04730	ENOG4105DZP	Membrane-associated zinc metalloprotease
N175_04740	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
N175_04745	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
N175_04750	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
N175_04755	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
N175_04760	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
N175_04765	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
N175_04770	ENOG4105C0B	DNA polymerase III (alpha subunit)
N175_04775	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
N175_04780	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
N175_04785	ENOG4105N7H	Cytochrome
N175_04795	ENOG4108YZA	Nitrogen regulatory protein pii
N175_04810	ENOG4105E9H	Lytic Murein transglycosylase
N175_04820	ENOG4105D1A	Methyltransferase
N175_04825	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
N175_04830	ENOG4108JDX	DNA polymerase iii, epsilon subunit
N175_04840	ENOG4107QPN	acyl-Coa dehydrogenase
N175_04845	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
N175_04850	ENOG4105E7A	Glutamine amidotransferase
N175_04855	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
N175_04860	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
N175_04865	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
N175_04870	ENOG4105FE9	pseudouridine synthase
N175_04890	ENOG4105E2D	ec 3.2.1.52
N175_04900	ENOG4105C59	p-type ATPase
N175_04905	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
N175_04910	ENOG4105UYK	outer membrane protein a
N175_04955	ENOG4107R88	Chemotaxis protein (CheV)
N175_04960	ENOG4105BZU	Histidine kinase
N175_04965	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
N175_04970	ENOG4108ZC9	flagellar basal-body rod protein flgc
N175_04975	ENOG4105W00	Flagellar hook capping protein
N175_04985	ENOG4105BZE	flagellar hook protein, FlgE
N175_04990	ENOG4108KPB	Flagellar basal-body rod protein FlgF
N175_04995	ENOG4105CGA	flagellar basal-body rod protein FlgG
N175_05000	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
N175_05005	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
N175_05010	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
N175_05020	ENOG4105DTJ	flagellar hook-associated protein
N175_05025	ENOG4105I03	Flagellin
N175_05030	ENOG4105I03	Flagellin
N175_05105	ENOG4105C3G	gtp-binding protein
N175_05110	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
N175_05115	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
N175_05120	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
N175_05130	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
N175_05135	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
N175_05140	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
N175_05145	ENOG4108YY7	Invasion gene expression up-regulator SirB
N175_05150	ENOG41063JG	Transcriptional regulator
N175_05155	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
N175_05160	ENOG4105CGH	5'-nucleotidase
N175_05165	ENOG4108Z66	YbaK ebsC protein
N175_05170	ENOG4105C2W	permease
N175_05185	ENOG4105CS1	NAD(P)H quinone oxidoreductase
N175_05190	ENOG4105K89	arsenate reductase
N175_05195	ENOG4105ERG	peptidase m48, ste24p
N175_05210	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_05215	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N175_05225	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
N175_05230	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
N175_05245	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
N175_05250	ENOG4105KUZ	arsenate reductase
N175_05270	ENOG4105QZU	Inner membrane protein YfeZ
N175_05275	ENOG4105EZR	dyp-type peroxidase family protein
N175_05280	ENOG4105I03	Flagellin
N175_05285	ENOG4105I03	Flagellin
N175_05290	ENOG4105I03	Flagellin
N175_05295	ENOG41063QE	flagellar protein FlaG
N175_05300	ENOG4107BRV	flagellar capping protein
N175_05310	ENOG4105MQ3	flagellar protein FliS
N175_05315	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
N175_05320	ENOG4105BZU	Histidine kinase
N175_05325	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
N175_05330	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
N175_05335	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
N175_05340	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
N175_05350	ENOG4108JIR	Flagellum-specific ATP synthase
N175_05370	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
N175_05375	ENOG4105DD5	Flagellar motor switch protein
N175_05380	ENOG4105VTB	flagellar biosynthesis protein fliO
N175_05385	ENOG4105CN7	Flagellar biosynthetic protein FliP
N175_05390	ENOG4105VS8	Flagellar biosynthetic protein fliq
N175_05395	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
N175_05400	ENOG4105D00	flagellar biosynthetic protein flhB
N175_05405	ENOG4108DG9	Smr protein MutS2
N175_05410	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
N175_05415	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
N175_05420	ENOG4105EN6	Membrane
N175_05425	ENOG4108BPE	-transporting atpase
N175_05430	ENOG4105MH2	YfcL protein
N175_05435	ENOG4105Q8W	reductase
N175_05440	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
N175_05445	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
N175_05450	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
N175_05455	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
N175_05460	ENOG41090R7	Ferric uptake
N175_05470	ENOG4105CMU	LysR family (Transcriptional regulator
N175_05475	ENOG4105VAW	lrga family
N175_05480	ENOG41067MG	lrgb family
N175_05485	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
N175_05495	ENOG4105EV9	Alpha Beta Hydrolase
N175_05500	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
N175_05505	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
N175_05515	ENOG4107QNR	UPF0135 protein
N175_05520	ENOG4105BZN	citrate synthase
N175_05525	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
N175_05530	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
N175_05535	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
N175_05540	ENOG4105E33	succinate dehydrogenase
N175_05545	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
N175_05550	ENOG4105C7S	Dehydrogenase
N175_05555	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
N175_05560	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
N175_05565	ENOG4105FAV	ABC, transporter
N175_05570	ENOG4105FDK	ABC transporter
N175_05575	ENOG4105NXV	High-affinity zinc uptake system protein
N175_05580	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
N175_05585	ENOG4105XFK	Ferrous iron transport protein A
N175_05605	ENOG4105C75	arginyL-tRNA synthetase
N175_05610	ENOG4106ZCM	YecM protein
N175_05615	ENOG4108JQM	Insulinase (Peptidase family M16)
N175_05620	ENOG4108BY2	phosphohistidine phosphatase
N175_05625	ENOG4105D7B	Flagellar biosynthesis protein flha
N175_05630	ENOG4105FZW	flagellar biosynthesis regulator FlhF
N175_05635	ENOG4107R21	site-determining protein
N175_05640	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
N175_05645	ENOG4108VYJ	response regulator receiver protein
N175_05650	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
N175_05655	ENOG4105CBS	Chea signal transduction histidine kinase
N175_05660	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
N175_05665	ENOG4107QJE	Chromosome Partitioning Protein
N175_05675	ENOG4108V3W	Chemotaxis protein, CheW
N175_05690	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
N175_05695	ENOG41060IM	Heme exporter protein
N175_05705	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
N175_05710	ENOG4105DA4	cytochrome c-type biogenesis protein
N175_05715	ENOG4107QX9	Thiol disulfide interChange protein
N175_05720	ENOG4108M1T	Cytochrome c-type biogenesis protein
N175_05730	ENOG410903C	(LipO)protein
N175_05745	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
N175_05750	ENOG4105M2J	Glutaredoxin
N175_05755	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
N175_05780	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
N175_05785	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
N175_05795	ENOG4105E68	Sulfatase
N175_05800	ENOG4105YDX	UPF0352 protein
N175_05805	ENOG4106V8H	Nucleoid-associated protein
N175_05815	ENOG4105DFD	Na H antiporter
N175_05820	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
N175_05825	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
N175_05830	ENOG4108EKI	Dehydrogenase
N175_05840	ENOG4105C03	ribonuclease
N175_05845	ENOG4105EI2	Pseudouridine synthase
N175_05850	ENOG4108UHJ	MAF-like protein
N175_05855	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
N175_05860	ENOG4105VGS	50s ribosomal protein l32
N175_05865	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
N175_05870	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
N175_05875	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
N175_05880	ENOG4105CHR	reductase
N175_05885	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
N175_05890	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
N175_05895	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
N175_05900	ENOG4105HHA	aminodeoxychorismate lyase
N175_05905	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
N175_05910	ENOG4107QRG	dna polymerase iii
N175_05915	ENOG4105F8V	Hydrolase, tatD family
N175_05920	ENOG4105CI1	PTS System
N175_05930	ENOG4105C8J	)-transporter
N175_05945	ENOG4108NRW	Phospholipase, patatin family
N175_05950	ENOG4105CA9	Pyruvate kinase
N175_05955	ENOG4105DAG	ROK family
N175_05960	ENOG4107R88	Chemotaxis protein (CheV)
N175_05965	ENOG4105UBK	short-chain dehydrogenase reductase
N175_05970	ENOG4105ERU	peptidase
N175_05985	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
N175_05990	ENOG4105DK2	UPF0207 protein
N175_05995	ENOG4105CHM	Aminotransferase
N175_06000	ENOG4105E4F	Isochorismate synthase
N175_06005	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
N175_06015	ENOG4108IPT	Naphthoate synthase
N175_06020	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
N175_06025	ENOG4105CEY	Amp-dependent synthetase and ligase
N175_06065	ENOG4108XM1	transcriptional regulator AsnC family
N175_06070	ENOG4105C29	acyl-CoA thioesterase
N175_06090	ENOG4106TD9	Diguanylate cyclase
N175_06110	ENOG4108IQE	Amp-dependent synthetase and ligase
N175_06120	ENOG4105EMU	Dehydrogenase
N175_06135	ENOG4105DHQ	Histidine kinase
N175_06140	ENOG4105DIJ	Phosphoethanolamine transferase
N175_06145	ENOG4105EW9	transcriptional regulator AsnC family
N175_06155	ENOG4105D0C	transport protein
N175_06165	ENOG41062D9	Histidine kinase
N175_06180	ENOG4105DIQ	Transcriptional regulator
N175_06185	ENOG4105C01	Dihydroxy-acid dehydratase
N175_06190	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
N175_06195	ENOG4105C6Z	Gluconate
N175_06200	ENOG4108UHU	Aldolase
N175_06215	ENOG4105RW8	MltA-interacting MipA family protein
N175_06220	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
N175_06225	ENOG4105C2D	reductase
N175_06230	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
N175_06235	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
N175_06260	ENOG4105C84	Histidine ammonia-lyase
N175_06265	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
N175_06290	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
N175_06315	ENOG4105BZU	Histidine kinase
N175_06320	ENOG4105BZU	Histidine kinase
N175_06325	ENOG4107QSI	ABC, transporter
N175_06330	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
N175_06335	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
N175_06340	ENOG4105C3U	ABC transporter
N175_06345	ENOG4108JQ7	(ABC) transporter
N175_06350	ENOG4105CHF	Glutathione S-transferase
N175_06355	ENOG4108DNC	Involved in acetate metabolism (By similarity)
N175_06360	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
N175_06365	ENOG4105PQ6	UPF0208 membrane protein
N175_06375	ENOG4105C7J	ABC transporter, permease
N175_06380	ENOG4108JJB	ABC transporter
N175_06385	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
N175_06390	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
N175_06395	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
N175_06400	ENOG4105D1H	recombination factor protein RarA
N175_06405	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
N175_06410	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
N175_06415	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
N175_06420	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
N175_06425	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
N175_06430	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
N175_06435	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
N175_06445	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
N175_06455	ENOG4108NVR	Methyl-accepting chemotaxis
N175_06460	ENOG4105K59	histidine triad (HIT) protein
N175_06485	ENOG4105D0Y	UPF0227 protein
N175_06490	ENOG4105CEP	NADH dehydrogenase
N175_06495	ENOG4106M3D	hemolysin
N175_06505	ENOG4108JA2	transcriptioN-repair coupling factor
N175_06515	ENOG4105D60	lipoprotein releasing system transmembrane protein
N175_06520	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
N175_06525	ENOG4105D60	lipoprotein releasing system transmembrane protein
N175_06535	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
N175_06540	ENOG4105BZ1	(ABC) transporter
N175_06545	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
N175_06550	ENOG4105W49	UPF0434 protein
N175_06555	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
N175_06565	ENOG4105ED1	spovr family
N175_06570	ENOG4106AKX	UPF0229 protein
N175_06575	ENOG4105CYN	Serine protein kinase
N175_06580	ENOG4105XWI	UPF0304 protein
N175_06590	ENOG4105F1A	Pyruvate formate-lyase
N175_06595	ENOG4108NVR	Methyl-accepting chemotaxis
N175_06605	ENOG4105C6N	Formate acetyltransferase
N175_06620	ENOG4108JEH	abc transporter atp-binding protein
N175_06625	ENOG4105E89	ABC transporter
N175_06630	ENOG4105DSP	amino acid AbC transporter
N175_06635	ENOG4106YG3	ABC transporter
N175_06640	ENOG4105CGK	Exodeoxyribonuclease III
N175_06645	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_06650	ENOG4106428	Protein of unknown function (DUF2496)
N175_06655	ENOG4108URS	primosomal replication protein n''
N175_06665	ENOG4105DVT	helicase
N175_06675	ENOG4105K5B	UPF0225 protein
N175_06680	ENOG4105D58	Diguanylate phosphodiesterase
N175_06685	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
N175_06690	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
N175_06700	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
N175_06705	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
N175_06710	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
N175_06720	ENOG4105C4M	(Ubiquinol oxidase) subunit I
N175_06725	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
N175_06735	ENOG4105KJB	cyd operon protein YbgE
N175_06740	ENOG4107YD3	Thioesterase
N175_06745	ENOG4105E02	MotA TolQ exbB proton channel
N175_06750	ENOG4105M8F	Biopolymer transport protein exbD tolR
N175_06760	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
N175_06765	ENOG4105KCK	Peptidoglycan-associated lipoprotein
N175_06770	ENOG4105UFD	tol-pal system protein YbgF
N175_06775	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
N175_06800	ENOG4105BZU	Histidine kinase
N175_06805	ENOG4108RNS	Exports L-alanine (By similarity)
N175_06830	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
N175_06855	ENOG4105BZU	Histidine kinase
N175_06860	ENOG4105C26	Dehydrogenase
N175_06875	ENOG41067SE	Tetr family transcriptional regulator
N175_06880	ENOG4107QPN	acyl-Coa dehydrogenase
N175_06915	ENOG4105CQB	FAD linked oxidase domain protein
N175_06930	ENOG4105C84	Histidine ammonia-lyase
N175_06935	ENOG4105CGP	Urocanate hydratase
N175_06940	ENOG41088SP	formiminoglutamate hydrolase
N175_06950	ENOG4105CZE	histidine utilization repressor
N175_06965	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
N175_06975	ENOG4105CQ2	DNA polymerase
N175_06980	ENOG4105WH1	Two component transcriptional regulator luxr family
N175_06985	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
N175_07025	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
N175_07030	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
N175_07035	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
N175_07045	ENOG4105FQ6	thiopurine methyltransferase
N175_07050	ENOG4107SDU	Methyl-accepting chemotaxis
N175_07055	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
N175_07065	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
N175_07070	ENOG41067MG	lrgb family
N175_07080	ENOG4105CJB	Exodeoxyribonuclease I
N175_07085	ENOG4108ETY	sodium dicarboxylate symporter
N175_07090	ENOG4105K4T	epimerase
N175_07095	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_07110	ENOG4108JJA	ABC, transporter
N175_07120	ENOG4108RC6	RTX toxin
N175_07125	ENOG4105EUK	rtx toxin RtxA
N175_07130	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
N175_07135	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
N175_07140	ENOG4108YZT	Adenosylcobinamide kinase
N175_07155	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
N175_07160	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
N175_07180	ENOG4107RSM	transcriptional regulator
N175_07190	ENOG4108VKG	metal-dependent hydrolase
N175_07205	ENOG41090FY	type IV pilus biogenesis stability protein PilW
N175_07210	ENOG4105CVG	Homoserine O-transsuccinylase
N175_07230	ENOG4107V40	secretion protein, HlyD family
N175_07245	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
N175_07250	ENOG4106YYS	transcriptional regulatory protein
N175_07260	ENOG4107R88	Chemotaxis protein (CheV)
N175_07275	ENOG4105BZU	Histidine kinase
N175_07300	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
N175_07375	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
N175_07400	ENOG4108UW8	fha domain-containing protein
N175_07465	ENOG4107VQW	regulatoR
N175_07495	ENOG4105M4H	endoribonuclease L-psp
N175_07505	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
N175_07510	ENOG4105C4M	(Ubiquinol oxidase) subunit I
N175_07525	ENOG4105E18	UPF0276 protein
N175_07550	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_07565	ENOG4105BZU	Histidine kinase
N175_07570	ENOG4105D7K	pfkb domain protein
N175_07575	ENOG4105C5Y	PTS System
N175_07585	ENOG4107R3K	hydrolase
N175_07590	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_07600	ENOG4105C72	UPF0176 protein
N175_07605	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
N175_07610	ENOG4105EHG	Permease protein
N175_07620	ENOG4106GFD	transport protein
N175_07625	ENOG41090AP	transport protein
N175_07630	ENOG4105WQ5	TonB family
N175_07635	ENOG41090JE	Utilization Protein
N175_07640	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
N175_07650	ENOG4105DKQ	ROK family
N175_07655	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
N175_07680	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
N175_07685	ENOG4105EAQ	(twin-arginine translocation) pathway signal
N175_07690	ENOG4105C5X	domain protein
N175_07705	ENOG41067TZ	transcriptional regulator, MarR family
N175_07710	ENOG4105C94	Transporter
N175_07715	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_07725	ENOG41080XQ	Signal transduction protein with cbs domains
N175_07730	ENOG4105CGF	Aromatic amino acid aminotransferase
N175_07735	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
N175_07740	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_07745	ENOG4108VYJ	response regulator receiver protein
N175_07755	ENOG4105CBS	Chea signal transduction histidine kinase
N175_07765	ENOG4108V3W	Chemotaxis protein, CheW
N175_07770	ENOG4105BZU	Histidine kinase
N175_07775	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
N175_07780	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
N175_07790	ENOG4105C5S	asparaginyl-tRNA synthetase
N175_07795	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_07800	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
N175_07805	ENOG4108K8S	endonuclease I
N175_07815	ENOG4105EJQ	L-serine dehydratase
N175_07820	ENOG4105C44	Serine transporter
N175_07825	ENOG4105P8F	nudix hydrolase
N175_07830	ENOG4105CRQ	synthase (Component I)
N175_07845	ENOG4105CM6	amino acid regulated cytosolic protein
N175_07850	ENOG4106K28	UPF0283 membrane protein
N175_07855	ENOG4108JU8	Transcriptional regulator
N175_07860	ENOG4105D9U	N-acetyltransferase
N175_07870	ENOG4105BZU	Histidine kinase
N175_07880	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
N175_07885	ENOG4108NVR	Methyl-accepting chemotaxis
N175_07890	ENOG4105C8P	)-transporter
N175_07895	ENOG4105BZU	Histidine kinase
N175_07900	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
N175_07910	ENOG4105VEQ	Cold shock protein
N175_07915	ENOG4105CUW	cytochrome C-TYPE protein
N175_07920	ENOG4105C1J	atp-dependent rna helicase
N175_07925	ENOG4105CS2	ec 3.2.1.21
N175_07930	ENOG4105DDV	Transcriptional regulator (LacI family
N175_07960	ENOG4105CFG	Acts as a chaperone (By similarity)
N175_07965	ENOG4105CFG	Acts as a chaperone (By similarity)
N175_07975	ENOG4105BZU	Histidine kinase
N175_07995	ENOG4105CQ7	ATP-dependent helicase
N175_08005	ENOG4108R4R	Iron-regulated virulence regulatory protein
N175_08010	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
N175_08030	ENOG4107RUZ	Sss sodium solute transporter superfamily
N175_08035	ENOG4105C2X	Arabinose 5-phosphate isomerase
N175_08040	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
N175_08050	ENOG4105DH8	myo-inositol catabolism
N175_08055	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
N175_08060	ENOG4105EDK	PfkB domain protein
N175_08075	ENOG4105C26	Dehydrogenase
N175_08085	ENOG4105CIB	oxidoreductase Domain protein
N175_08090	ENOG4105CTD	carboxy-peptidase
N175_08165	ENOG4107UNZ	domain protein
N175_08195	ENOG4105CTD	carboxy-peptidase
N175_08200	ENOG410829K	Lysine exporter protein (Lyse ygga)
N175_08205	ENOG4105BZG	amino acid carrier protein
N175_08220	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
N175_08225	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
N175_08230	ENOG4105F1J	Homogentisate 1,2-dioxygenase
N175_08240	ENOG4108RXX	maleylacetoacetate isomerase
N175_08280	ENOG4109015	Biopolymer transport protein exbD tolR
N175_08295	ENOG4108NRW	Phospholipase, patatin family
N175_08305	ENOG4107QI1	Mate efflux family protein
N175_08315	ENOG4105FGM	Fructosamine kinase
N175_08325	ENOG4107TT5	NLP P60 protein
N175_08330	ENOG4108N3W	hemolysin secretion protein
N175_08340	ENOG4106IUH	DTW domain containing protein
N175_08345	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
N175_08355	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
N175_08360	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
N175_08365	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
N175_08370	ENOG4107RCV	ABC transporter, permease
N175_08375	ENOG4105C4Y	ABC transporter
N175_08380	ENOG4105CXY	transporter
N175_08385	ENOG4105BZU	Histidine kinase
N175_08390	ENOG4108KX4	response regulator
N175_08395	ENOG4105C5H	ABC transporter
N175_08405	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
N175_08410	ENOG4107RUE	extracellular solute-binding protein family 1
N175_08415	ENOG4107RUE	extracellular solute-binding protein family 1
N175_08420	ENOG4105D38	putrescine abc transporter
N175_08425	ENOG4105F38	ABC transporter, permease
N175_08430	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
N175_08450	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
N175_08455	ENOG4105Q9Y	Universal stress protein
N175_08460	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
N175_08475	ENOG4105C59	p-type ATPase
N175_08485	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
N175_08500	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
N175_08525	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
N175_08530	ENOG4105DAN	ATP-dependent protease
N175_08535	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
N175_08550	ENOG4105C5H	ABC transporter
N175_08560	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
N175_08565	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
N175_08570	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
N175_08575	ENOG4105C7I	Dehydrogenase
N175_08585	ENOG4105CD8	aminopeptidase N
N175_08595	ENOG4105CN1	protease
N175_08600	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
N175_08605	ENOG4108ZGC	gaf domain protein
N175_08610	ENOG4105BZ1	(ABC) transporter
N175_08615	ENOG4105H2K	paraquat-inducible protein a
N175_08620	ENOG4105DY2	Paraquat-inducible protein b
N175_08625	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
N175_08630	ENOG4105QNR	S1 RNA binding domain protein
N175_08650	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
N175_08660	ENOG4105BZU	Histidine kinase
N175_08670	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
N175_08675	ENOG4107QXX	ABC transporter
N175_08680	ENOG4105EZ7	amino acid ABC transporter
N175_08685	ENOG4105DRP	amino acid AbC transporter
N175_08690	ENOG4105CDA	abc transporter atp-binding protein
N175_08695	ENOG4108MN8	Membrane
N175_08700	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
N175_08705	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
N175_08710	ENOG4105DR4	Methyltransferase
N175_08715	ENOG410607W	Transposase
N175_08745	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
N175_08750	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
N175_08755	ENOG410667J	hydrolase
N175_08770	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
N175_08775	ENOG4105C7F	AcnD-accessory protein PrpF
N175_08780	ENOG4108I0Z	Aconitate hydratase
N175_08785	ENOG4105BZN	citrate synthase
N175_08790	ENOG4105CR4	methylisocitrate lyase
N175_08820	ENOG4107EXC	regulatoR
N175_08825	ENOG4105GR3	Histidine kinase
N175_08830	ENOG41080IJ	Diacylglycerol kinase
N175_08835	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
N175_08840	ENOG4105EJC	lysr family transcriptional regulator
N175_08845	ENOG4107SDZ	Galactoside transport system permease protein mglC
N175_08880	ENOG4108YRF	PTS System
N175_08890	ENOG4108CIP	transcriptional regulator
N175_08900	ENOG4105DM4	PTS System
N175_08905	ENOG4105EIP	mannose-6-phosphate isomerase
N175_08925	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
N175_08930	ENOG4105YGP	holo-ACP synthase CitX
N175_08935	ENOG4105CHY	citrate lyase, alpha
N175_08940	ENOG4105CI0	Citrate lyase
N175_08945	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
N175_08950	ENOG4106YYS	transcriptional regulatory protein
N175_08955	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
N175_08960	ENOG4105D9Q	decarboxylase (Beta subunit)
N175_08965	ENOG4107QSA	Oxaloacetate decarboxylase
N175_08980	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
N175_09000	ENOG4108N3W	hemolysin secretion protein
N175_09010	ENOG4108N3W	hemolysin secretion protein
N175_09015	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
N175_09020	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
N175_09025	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
N175_09030	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
N175_09060	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_09065	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
N175_09085	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
N175_09100	ENOG4108I0Y	(ABC) transporter
N175_09105	ENOG4105UQX	Mate efflux family protein
N175_09110	ENOG4105CGD	Nad-dependent epimerase dehydratase
N175_09120	ENOG4105C2C	drug resistance transporter, Bcr CflA
N175_09125	ENOG4105I08	Pseudouridine synthase
N175_09130	ENOG4105CFI	type iii restriction protein res subunit
N175_09145	ENOG4105EB3	Histidine kinase
N175_09150	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
N175_09190	ENOG4108W1A	pseudouridine synthase
N175_09195	ENOG4105C8J	)-transporter
N175_09205	ENOG4105C28	cystathionine
N175_09210	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
N175_09220	ENOG4105YYT	phage shock protein B
N175_09225	ENOG41087YS	Phage shock protein A
N175_09230	ENOG4105E51	psp operon transcriptional activator
N175_09235	ENOG4108J59	Extracellular solute-binding protein, family 5
N175_09240	ENOG4108I5W	peptide transport system, permease protein
N175_09245	ENOG4108EU3	peptide transport system, permease
N175_09250	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
N175_09255	ENOG4108JQ2	peptide transport system atp-binding protein
N175_09270	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
N175_09280	ENOG4108J2R	molybdopterin oxidoreductase
N175_09295	ENOG4105TMB	Formate nitrite transporter
N175_09320	ENOG4105GFG	DUF218 domain
N175_09325	ENOG4107104	thymidine kinase
N175_09330	ENOG4105C9M	aspartyl-trna synthetase
N175_09335	ENOG41081XQ	Conserved Protein
N175_09340	ENOG4108N4M	Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enlarged vesicles, which are essential to create a favorable environment where Salmonella can replicate and avoid immune defenses of the host cell
N175_09345	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
N175_09350	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
N175_09355	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
N175_09370	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
N175_09375	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
N175_09380	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
N175_09385	ENOG4106371	Methyltransferase
N175_09390	ENOG4107S90	membrAne
N175_09395	ENOG4106WF9	DNA-binding transcriptional regulator TorR
N175_09405	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
N175_09410	ENOG4105ETE	Transcriptional regulator (LacI family
N175_09415	ENOG4105HP8	regulator of competence-specific genes
N175_09435	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
N175_09440	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
N175_09445	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
N175_09450	ENOG4105RKX	Protein of unknown function (DUF2498)
N175_09455	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
N175_09460	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
N175_09465	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
N175_09470	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
N175_09475	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
N175_09480	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
N175_09485	ENOG4105VEQ	Cold shock protein
N175_09495	ENOG4108R99	pseudouridine synthase
N175_09500	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
N175_09505	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
N175_09520	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
N175_09525	ENOG4105CIH	Imidazole acetol-phosphate transaminase
N175_09530	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
N175_09535	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
N175_09540	ENOG4107S6Z	Na H antiporter
N175_09545	ENOG4108YX2	DNA-binding protein
N175_09550	ENOG4107RE1	Inosine-guanosine kinase
N175_09560	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
N175_09565	ENOG41075W9	High frequency lysogenization protein HflD homolog
N175_09570	ENOG4107QTF	adenylosuccinate lyase
N175_09575	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
N175_09585	ENOG4105BZU	Histidine kinase
N175_09610	ENOG4105DWU	Membrane
N175_09620	ENOG4105DY8	decarboxylase
N175_09625	ENOG4106KNT	transcriptional regulator
N175_09635	ENOG41090BQ	Glutaredoxin
N175_09645	ENOG4105C8V	SAICAR synthetase
N175_09655	ENOG4107R1I	NAD-dependent malic enzyme
N175_09665	ENOG4107GZ4	SanA protein
N175_09670	ENOG4105C9B	Cysteine desulfurase
N175_09680	ENOG4105BZU	Histidine kinase
N175_09685	ENOG4105C3M	thioredoxin reductase
N175_09690	ENOG4108JJ9	ABC, transporter
N175_09695	ENOG4108JJ8	(ABC) transporter
N175_09710	ENOG4105DU6	RNA polymerase
N175_09720	ENOG4105BZU	Histidine kinase
N175_09725	ENOG4105FE9	pseudouridine synthase
N175_09730	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
N175_09735	ENOG4105DB7	PHP domain protein
N175_09745	ENOG4105CRQ	synthase (Component I)
N175_09750	ENOG4105DDQ	anthranilate synthase
N175_09755	ENOG4108I0Q	anthranilate phosphoribosyltransferase
N175_09760	ENOG4105DK0	Indole-3-glycerol phosphate synthase
N175_09765	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
N175_09770	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
N175_09775	ENOG4105CK2	sodium dicarboxylate symporter
N175_09790	ENOG4107835	probably involved in intracellular septation (By similarity)
N175_09795	ENOG4105NAU	thioesterase Superfamily protein
N175_09800	ENOG4105K9H	YciI-like protein
N175_09810	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
N175_09815	ENOG4105DZ2	Transcriptional regulator
N175_09830	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
N175_09840	ENOG4105CCT	upf0313 protein
N175_09850	ENOG4105RHG	
N175_09860	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
N175_09875	ENOG4105E1F	short-chain dehydrogenase reductase
N175_09885	ENOG4105D0M	Protease HtpX homolog
N175_09895	ENOG4105CNU	cell division protein FtsK
N175_09900	ENOG4105EW9	transcriptional regulator AsnC family
N175_09905	ENOG4105DCF	alanine dehydrogenase
N175_09915	ENOG4107R11	Transcriptional regulator
N175_09925	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
N175_09930	ENOG4105CFV	Tetratricopeptide repeat protein
N175_09935	ENOG4105Q4A	inner membrane protein yciS
N175_09940	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
N175_09945	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
N175_09950	ENOG4105CAT	Cytidine monophosphate kinase
N175_09955	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
N175_09960	ENOG4105EIN	peptidylprolyl cis-trans isomerase
N175_09965	ENOG4105K70	DNA-binding protein
N175_09970	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
N175_09975	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
N175_09980	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
N175_09985	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
N175_09995	ENOG4105CQZ	Histidine kinase
N175_10000	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
N175_10005	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
N175_10010	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
N175_10015	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
N175_10020	ENOG4108JP0	extracellular solute-binding protein family 1
N175_10025	ENOG4105E0F	Histidine kinase
N175_10030	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
N175_10035	ENOG4105CNG	UPF0061 protein
N175_10040	ENOG4105EJQ	L-serine dehydratase
N175_10050	ENOG4105C1J	atp-dependent rna helicase
N175_10060	ENOG4105C94	Transporter
N175_10065	ENOG4105C3R	Methionine synthase
N175_10075	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
N175_10095	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
N175_10105	ENOG4105D9N	nucleoside
N175_10110	ENOG4105EJC	lysr family transcriptional regulator
N175_10115	ENOG4105CVE	Lytic murein transglycosylase
N175_10125	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
N175_10130	ENOG4107QMS	site-determining protein
N175_10135	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
N175_10140	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
N175_10145	ENOG4105CEY	Amp-dependent synthetase and ligase
N175_10150	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
N175_10165	ENOG41072GX	Peptidase M22 Glycoprotease
N175_10170	ENOG4105DVT	helicase
N175_10180	ENOG4105CIY	formyltetrahydrofolate deformylase
N175_10185	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
N175_10190	ENOG4105D07	Signal peptide peptidase, SppA
N175_10195	ENOG4105HDK	L-asparaginase
N175_10200	ENOG4105VUT	cytoplasmic protein
N175_10210	ENOG4105E0X	reductase
N175_10220	ENOG4105DSB	aldose 1-epimerase
N175_10225	ENOG4105DHI	Methyltransferase
N175_10240	ENOG4108ZZ3	UPF0260 protein
N175_10245	ENOG4105KRS	Proteinase inhibitor
N175_10250	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
N175_10255	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
N175_10260	ENOG4107QMP	dna polymerase iii subunits gamma and tau
N175_10265	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
N175_10270	ENOG4105WD1	Membrane
N175_10280	ENOG4105I93	response regulator
N175_10285	ENOG4105EJC	lysr family transcriptional regulator
N175_10290	ENOG41069NU	Nitroreductase
N175_10295	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
N175_10300	ENOG4105CHU	acetyl-coa acetyltransferase
N175_10310	ENOG4108AEY	RNA polymerase sigma factor
N175_10320	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
N175_10325	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
N175_10330	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
N175_10335	ENOG4108GAE	asmA family
N175_10340	ENOG4105DBI	uridine monophosphokinase
N175_10345	ENOG4105D1F	ATP-binding protein
N175_10350	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
N175_10360	ENOG4108I5U	Uridine phosphorylase
N175_10380	ENOG4105BZU	Histidine kinase
N175_10385	ENOG4108ZAF	Molybdopterin
N175_10390	ENOG4105M00	molybdopterin converting factor, subunit 1
N175_10395	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
N175_10400	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
N175_10405	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
N175_10410	ENOG4105CHW	UPF0052 protein
N175_10425	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
N175_10445	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
N175_10450	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
N175_10455	ENOG4105E4F	Isochorismate synthase
N175_10460	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
N175_10465	ENOG4105WQI	isochorismatase
N175_10480	ENOG410607W	Transposase
N175_10485	ENOG4105CEY	Amp-dependent synthetase and ligase
N175_10495	ENOG4105E93	esterase
N175_10505	ENOG4107RBR	Receptor
N175_10520	ENOG4108R3D	Electron transport complex
N175_10530	ENOG4105D6A	Electron transport complex
N175_10535	ENOG4108UQQ	Electron transport complex
N175_10540	ENOG4105DZB	Electron transport complex
N175_10545	ENOG4105CSM	endonuclease III
N175_10550	ENOG4108UYE	Lactoylglutathione lyase
N175_10555	ENOG4105EIY	sodium-type flagellar protein motY
N175_10560	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
N175_10565	ENOG4105D3Y	Na H antiporter
N175_10570	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
N175_10575	ENOG4105E96	Colicin v production protein
N175_10580	ENOG4108S3P	Sporulation domain protein
N175_10585	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
N175_10590	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
N175_10595	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
N175_10610	ENOG4105CX6	glutaminyL-tRNA synthetase
N175_10615	ENOG4105CI1	PTS System
N175_10620	ENOG4105CE4	GlcNAc 6-P deacetylase
N175_10625	ENOG4105E2R	ROK family
N175_10630	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
N175_10640	ENOG4105CAQ	asparagine synthetase
N175_10645	ENOG4105MDZ	Transcriptional activator rfaH
N175_10650	ENOG4105DUX	Transporter
N175_10655	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
N175_10660	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
N175_10665	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
N175_10675	ENOG4108DQ1	activator toxR
N175_10690	ENOG4108RE9	Phosphodiesterase
N175_10695	ENOG4105ECP	epimerase
N175_10700	ENOG4107QR8	Thioredoxin
N175_10710	ENOG4107QX8	SPFH domain, Band 7 family protein
N175_10720	ENOG4108Z6Z	Transcriptional regulator
N175_10725	ENOG410607W	Transposase
N175_10735	ENOG41081QG	Porin Gram-negative type
N175_10740	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
N175_10745	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
N175_10750	ENOG4105EXN	Sulfate transport protein CysZ
N175_10755	ENOG4105C6T	cysteine synthase
N175_10760	ENOG4105KZ7	phosphocarrier protein hpr
N175_10765	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
N175_10770	ENOG4105C5Y	PTS System
N175_10775	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
N175_10780	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
N175_10785	ENOG4105C9A	Phoh family
N175_10790	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
N175_10795	ENOG4108JU5	Magnesium and cobalt efflux protein
N175_10800	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
N175_10805	ENOG4107PAI	alpha helical protein
N175_10810	ENOG4105C8T	Leucyl-tRNA synthetase
N175_10815	ENOG4108U2H	Rare lipoprotein B
N175_10820	ENOG4105DJF	DNA polymerase III, delta' subunit
N175_10825	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
N175_10830	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
N175_10835	ENOG4105CJN	penicillin-binding protein
N175_10840	ENOG4105CNI	cell division protein FtsW
N175_10845	ENOG4105K6T	rare lipoprotein A
N175_10850	ENOG4105DZ1	carboxypeptidase
N175_10855	ENOG4108Z43	UPF0250 protein
N175_10865	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
N175_10875	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
N175_10895	ENOG4105DAY	polysaccharide export protein
N175_10900	ENOG4108QV3	biosynthesis protein
N175_10920	ENOG4108MA4	Peptidase M66
N175_10925	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
N175_10935	ENOG4105D7W	serine acetyltransferase
N175_10970	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
N175_10980	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
N175_10990	ENOG4105KJF	protein tyrosine phosphatase
N175_10995	ENOG4105BZS	acriflavin resistance protein
N175_11000	ENOG410624X	efflux transporter, rnd family, mfp subunit
N175_11040	ENOG4105JJR	Histidine kinase
N175_11045	ENOG4107EXC	regulatoR
N175_11050	ENOG4105CG3	alpha amylase, catalytic region
N175_11055	ENOG4105C5Y	PTS System
N175_11060	ENOG4105D4X	repressor
N175_11070	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
N175_11080	ENOG4108UMI	ABC transporter, permease
N175_11085	ENOG4105D01	(LipO)protein
N175_11090	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
N175_11095	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
N175_11100	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
N175_11110	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
N175_11120	ENOG4105EWT	decarboxylase family
N175_11125	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
N175_11130	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
N175_11135	ENOG4105M08	Membrane
N175_11140	ENOG4105ETT	transcriptional Regulator, LysR family
N175_11145	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
N175_11150	ENOG4106VK6	Flagellar motor protein
N175_11155	ENOG4105E14	MotA TolQ exbB proton channel
N175_11165	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
N175_11170	ENOG4105CTB	Polyprenyl synthetase
N175_11175	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
N175_11180	ENOG4105DR9	pseudouridine synthase
N175_11185	ENOG4105WP7	tRNA pseudouridine synthase C
N175_11215	ENOG4108UPT	UPF0178 protein
N175_11225	ENOG4105NRA	50s ribosomal protein l31 type b
N175_11230	ENOG4108R96	Methyltransferase, YaeB family
N175_11235	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
N175_11240	ENOG4108Q2J	Inner membrane protein YebE
N175_11245	ENOG4105W1I	UPF0253 protein
N175_11260	ENOG4108ETH	Formylglycinamide ribotide synthetase
N175_11265	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
N175_11275	ENOG4108Z6B	deaminase
N175_11280	ENOG4105CC0	LysR family Transcriptional regulator
N175_11290	ENOG4105C4W	S-formylglutathione hydrolase
N175_11295	ENOG4105CFC	Transporter
N175_11325	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
N175_11330	ENOG4105CFG	Acts as a chaperone (By similarity)
N175_11340	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
N175_11350	ENOG4105C0F	tryptophanase EC 4.1.99.1
N175_11355	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
N175_11360	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
N175_11365	ENOG4105VDB	UPF0125 protein
N175_11370	ENOG4108Z1B	Cyclase dehydrase
N175_11375	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
N175_11380	ENOG4105DFP	Integrase
N175_11385	ENOG4105CVR	type I restriction-modification system
N175_11405	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
N175_11410	ENOG4106H3A	restriction
N175_11425	ENOG4108YGG	dna repair protein
N175_11495	ENOG4105JXR	Protein of unknown function (DUF3296)
N175_11550	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
N175_11555	ENOG4108VGW	abc transporter atp-binding protein
N175_11560	ENOG4105CXZ	ABC transporter, permease
N175_11565	ENOG4105VNH	ABC transporter solute-binding protein
N175_11575	ENOG4105XZD	Fe-S protein
N175_11585	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
N175_11595	ENOG4105C94	Transporter
N175_11605	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
N175_11610	ENOG4105BZG	amino acid carrier protein
N175_11615	ENOG4106HK8	GPR1 FUN34 yaaH family protein
N175_11625	ENOG4105DWF	phosphomethylpyrimidine kinase
N175_11630	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
N175_11635	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
N175_11640	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
N175_11650	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
N175_11655	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
N175_11660	ENOG4105N21	Membrane
N175_11665	ENOG4105CUT	histidyl-tRNA synthetase
N175_11670	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
N175_11675	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
N175_11685	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
N175_11690	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
N175_11695	ENOG4105WVQ	Fe-S assembly protein IscX
N175_11700	ENOG4108ZIT	Ferredoxin, 2FE-2S
N175_11705	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
N175_11710	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
N175_11715	ENOG4108Z4V	iron-sulfur cluster assembly
N175_11720	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
N175_11725	ENOG4105C3J	Cysteine desulfurase
N175_11730	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
N175_11735	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
N175_11740	ENOG4105ECY	inositol monophosphatase
N175_11745	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
N175_11750	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
N175_11755	ENOG4105VIE	preprotein translocase, subunit YajC
N175_11760	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
N175_11765	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
N175_11770	ENOG4105W87	Cbs domain
N175_11775	ENOG4108I9X	Isocitrate lyase
N175_11785	ENOG4107QP3	malate synthase g
N175_11790	ENOG4105C5Q	Transcriptional regulator
N175_11795	ENOG4105D3R	alkyl hydroperoxide reductase
N175_11800	ENOG4106N3A	copper homeostasis protein cutc
N175_11810	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
N175_11815	ENOG4105E2Z	phosphate ABC transporter (Permease
N175_11820	ENOG4105C8U	phosphate abc transporter
N175_11825	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
N175_11830	ENOG4105C9X	ppx gppa phosphatase
N175_11840	ENOG4105BZU	Histidine kinase
N175_11845	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
N175_11850	ENOG4105DH7	May be involved in recombination (By similarity)
N175_11855	ENOG4105CFP	Peptidase U32
N175_11860	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
N175_11910	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
N175_11920	ENOG4105C34	Pseudouridine synthase
N175_11925	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N175_11935	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
N175_11945	ENOG4107XW0	Spermidine putrescine ABC transporter periplasmic spermidine putrescine-binding protein
N175_11950	ENOG4108K0B	C-di-gmp phosphodiesterase
N175_11955	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
N175_11960	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
N175_11965	ENOG4107SC1	transglycosylase
N175_11970	ENOG4105C5H	ABC transporter
N175_11985	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
N175_11990	ENOG4108HRK	Histidine kinase
N175_11995	ENOG4108NEV	two component transcriptional regulator, LytTR family
N175_12000	ENOG4108NEV	two component transcriptional regulator, LytTR family
N175_12005	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
N175_12010	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
N175_12015	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N175_12035	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
N175_12040	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
N175_12045	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
N175_12050	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
N175_12055	ENOG4105DTN	riboflavin biosynthesis protein ribF
N175_12060	ENOG4105CJR	Integral membrane protein (MviN
N175_12065	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
N175_12070	ENOG41080HT	Transcriptional regulator, arsr family
N175_12075	ENOG41063Z6	transcriptional regulator, lysR family
N175_12085	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
N175_12090	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
N175_12250	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
N175_12255	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
N175_12260	ENOG4105HF0	Membrane
N175_12265	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
N175_12270	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
N175_12275	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
N175_12280	ENOG4105CPC	Aldo Keto reductase
N175_12290	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
N175_12295	ENOG4105CRK	lysyL-tRNA synthetase
N175_12300	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
N175_12305	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
N175_12310	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
N175_12315	ENOG4105C1J	atp-dependent rna helicase
N175_12320	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
N175_12325	ENOG4105BZU	Histidine kinase
N175_12330	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
N175_12345	ENOG4108YYD	acetyltransferase
N175_12350	ENOG4105XPQ	lipid carrier protein
N175_12355	ENOG4105BZU	Histidine kinase
N175_12360	ENOG4105CFP	Peptidase U32
N175_12365	ENOG4106RZ4	Peptidase U32
N175_12375	ENOG41062A4	Transcriptional regulator
N175_12385	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
N175_12390	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
N175_12395	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
N175_12400	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
N175_12405	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
N175_12410	ENOG4105CHV	Transcription elongation factor NusA
N175_12415	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
N175_12440	ENOG4105EEI	dihydropteroate synthase
N175_12445	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
N175_12450	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
N175_12455	ENOG4105HBR	Rna-binding protein
N175_12460	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
N175_12465	ENOG4105FCK	Membrane
N175_12470	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
N175_12475	ENOG4105CJW	magnesium transporter
N175_12485	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
N175_12490	ENOG4105DR5	peptidase
N175_12505	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
N175_12510	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
N175_12520	ENOG4105IPI	Membrane
N175_12525	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
N175_12530	ENOG4105BZU	Histidine kinase
N175_12545	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
N175_12550	ENOG4105C3U	ABC transporter
N175_12555	ENOG4108JQ7	(ABC) transporter
N175_12565	ENOG4105RD7	BadF BadG BcrA BcrD
N175_12570	ENOG4105E2D	ec 3.2.1.52
N175_12580	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
N175_12605	ENOG4108YZA	Nitrogen regulatory protein pii
N175_12610	ENOG4105XTV	UPF0231 protein
N175_12615	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
N175_12620	ENOG4107QQ0	gntp family
N175_12625	ENOG4105BZW	Glycerate kinase
N175_12630	ENOG4107QIJ	Aconitate hydratase 2
N175_12635	ENOG4105D78	K07001 NTE family protein
N175_12640	ENOG4105BZ4	penicillin-binding protein
N175_12645	ENOG4105CQ7	ATP-dependent helicase
N175_12650	ENOG4105PW4	Sugar fermentation stimulation protein homolog
N175_12655	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N175_12660	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
N175_12665	ENOG4105DJ0	Poly(A) Polymerase
N175_12670	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N175_12675	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
N175_12680	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
N175_12690	ENOG4105E3A	(ABC) transporter
N175_12695	ENOG4105DA5	(ABC) transporter
N175_12700	ENOG4105CHH	sulfate transporter
N175_12705	ENOG41077A9	carbonic anhydrase
N175_12710	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
N175_12715	ENOG410630P	Transcriptional regulator
N175_12720	ENOG4107QN2	dihydrolipoyl dehydrogenase
N175_12725	ENOG4107QSN	dihydrolipoamide acetyltransferase
N175_12730	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
N175_12735	ENOG41073TP	transcriptional regulator
N175_12740	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
N175_12745	ENOG4105T95	Thiol disulfide interChange protein
N175_12750	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
N175_12755	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
N175_12765	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
N175_12770	ENOG4105X0D	Fimbrial protein
N175_12785	ENOG4105D7Q	type ii secretion system
N175_12790	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
N175_12795	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
N175_12800	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
N175_12805	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
N175_12810	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
N175_12815	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
N175_12820	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
N175_12825	ENOG4105K5M	30s ribosomal protein S16
N175_12830	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N175_12835	ENOG4106KVJ	cytochrome C assembly protein
N175_12840	ENOG4108JU6	CBS domain protein
N175_12845	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
N175_12850	ENOG4105D9M	gamma-glutamylcysteine synthetase
N175_12860	ENOG4105W39	Membrane
N175_12865	ENOG4105CPQ	Dehydrogenase
N175_12870	ENOG4105D9Q	decarboxylase (Beta subunit)
N175_12875	ENOG4107QSA	Oxaloacetate decarboxylase
N175_12925	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
N175_12930	ENOG4105CFH	Aspartokinase
N175_12935	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
N175_12940	ENOG4105Y3E	Modulates RecA activity (By similarity)
N175_12945	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
N175_12950	ENOG4107TH8	cina domain protein
N175_12955	ENOG4108IJ6	ABC transporter
N175_12960	ENOG4105ECW	sulfate abc transporter
N175_12965	ENOG4108I5D	sulfate abc transporter
N175_12970	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
N175_12975	ENOG4105C6T	cysteine synthase
N175_12980	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
N175_12985	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
N175_12990	ENOG4108K5P	(LipO)protein
N175_12995	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
N175_13000	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
N175_13005	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
N175_13010	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
N175_13015	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
N175_13020	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
N175_13025	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
N175_13030	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N175_13035	ENOG4107ZVW	dihydroneopterin aldolase
N175_13040	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
N175_13050	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
N175_13055	ENOG4105VCC	30S ribosomal protein S21
N175_13060	ENOG4105KTH	gatB Yqey
N175_13065	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
N175_13070	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
N175_13085	ENOG4105CAF	HipA N-terminal domain protein
N175_13105	ENOG4105C4R	Atp-dependent dna helicase
N175_13135	ENOG4105DQ6	Transposase
N175_13210	ENOG4105DQ6	Transposase
N175_13275	ENOG4105D70	Integrase catalytic subunit
N175_13280	ENOG4105F5W	AtP-binding protein
N175_13305	ENOG4106K8T	Toxic component of a toxin-antitoxin (TA) module. A stable (half-life 27.6 minutes) endoribonuclease that in the absence of cognate antitoxin RnlB causes generalized RNA degradation. Degrades late enterobacteria phage T4 mRNAs, protecting the host against T4 reproduction. Activity is inhibited by cognate antitoxin RnlB and by enterobacteria phage T4 protein Dmd. Targets cyaA mRNA
N175_13310	ENOG4106BHJ	Antitoxin component of a toxin-antitoxin (TA) module. A labile antitoxin (half-life of 2.1 minutes) that inhibits the endonuclease activity of cognate toxin RnlA but not that of non- cognate toxin LsoA
N175_13430	ENOG4105CS6	Rhs element vgr protein
N175_13435	ENOG4108WC9	type VI secretion system effector, hcp1 family
N175_13440	ENOG4108YZN	class I peptide chain release factor
N175_13450	ENOG4107VGF	ig domain protein group 2 domain protein
N175_13455	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
N175_13460	ENOG410804X	Transcriptional regulator
N175_13475	ENOG4105CA9	Pyruvate kinase
N175_13480	ENOG4105BZU	Histidine kinase
N175_13490	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
N175_13495	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
N175_13500	ENOG4105D64	Mechanosensitive ion channel
N175_13505	ENOG4105D2N	Aldolase
N175_13510	ENOG4105BZA	Phosphoglycerate kinase
N175_13515	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
N175_13520	ENOG4105D05	Receptor
N175_13525	ENOG4108R4R	Iron-regulated virulence regulatory protein
N175_13530	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
N175_13540	ENOG4105RWS	endonuclease I
N175_13545	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
N175_13550	ENOG4105D7Z	glutathione synthase
N175_13555	ENOG4108UJU	UPF0301 protein
N175_13565	ENOG4105CZX	twitching motility protein
N175_13570	ENOG4105CZX	twitching motility protein
N175_13575	ENOG4105DFA	alanine racemase domain protein
N175_13580	ENOG4105II7	pyrroline-5-carboxylate reductase
N175_13585	ENOG4108VIA	integral membrane protein
N175_13590	ENOG4105VZ9	UPF0235 protein
N175_13600	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
N175_13605	ENOG4105CSA	Coproporphyrinogen iii oxidase
N175_13610	ENOG4105CSV	Glutaminase
N175_13615	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
N175_13620	ENOG4105CEN	a g-specific adenine glycosylase
N175_13625	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
N175_13630	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
N175_13680	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
N175_13685	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
N175_13695	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
N175_13700	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
N175_13705	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
N175_13710	ENOG4105NWN	ApaG protein
N175_13715	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
N175_13725	ENOG4107XM3	UPF0442 protein
N175_13730	ENOG4105DWK	Membrane
N175_13735	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
N175_13740	ENOG4105K46	50S ribosomal protein l27
N175_13745	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
N175_13750	ENOG4105EAH	synthase
N175_13755	ENOG4105D5Q	Arginine ornithine antiporter
N175_13760	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
N175_13765	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
N175_13785	ENOG41081QV	Universal stress protein
N175_13905	ENOG4105CEU	Arginine dihydrolase
N175_13910	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
N175_13920	ENOG4105QD6	exported protein
N175_13925	ENOG4105C03	ribonuclease
N175_13935	ENOG4105VQ7	Rod shape-determining protein MreD
N175_13940	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
N175_13945	ENOG4105DFF	Rod shape-determining protein mreb
N175_13990	ENOG4105D7Q	type ii secretion system
N175_13995	ENOG4107QHF	type ii secretion system protein e
N175_14030	ENOG41062P1	Diguanylate cyclase phosphodiesterase
N175_14035	ENOG4108UUM	single-stranded DNA-binding protein
N175_14040	ENOG41086KC	Transcriptional regulator
N175_14045	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
N175_14060	ENOG4105CJW	magnesium transporter
N175_14075	ENOG4105C5R	Aminotransferase
N175_14080	ENOG4105CFH	Aspartokinase
N175_14085	ENOG4105C3R	Methionine synthase
N175_14090	ENOG4105EEQ	Na H antiporter
N175_14120	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
N175_14125	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
N175_14130	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
N175_14150	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
N175_14155	ENOG4105MYN	Zinc uptake regulation protein
N175_14165	ENOG4107QP8	phosphohexose isomerase
N175_14170	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
N175_14175	ENOG4105CDU	Replicative dna helicase
N175_14185	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
N175_14190	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
N175_14195	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
N175_14200	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
N175_14205	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
N175_14215	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
N175_14220	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
N175_14230	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
N175_14235	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
N175_14240	ENOG4105WWK	YheO domain protein
N175_14245	ENOG4108V1T	peptidylprolyl cis-trans isomerase
N175_14255	ENOG41069P5	Protein slyX homolog
N175_14265	ENOG4105EPW	hflc protein
N175_14270	ENOG4107QJR	hflk protein
N175_14275	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
N175_14280	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
N175_14285	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
N175_14290	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
N175_14295	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
N175_14300	ENOG4105K8N	protein family UPF0079, ATPase
N175_14320	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
N175_14325	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
N175_14330	ENOG4105DJ4	phosphatidylserine decarboxylase
N175_14335	ENOG4107QWE	)-transporter
N175_14340	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_14350	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
N175_14355	ENOG41063SB	peptidase
N175_14365	ENOG41062JF	Transcriptional regulator
N175_14370	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
N175_14375	ENOG4105E09	nadh pyrophosphatase
N175_14380	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
N175_14385	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
N175_14390	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
N175_14395	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
N175_14400	ENOG4108VZM	50s ribosomal protein L10
N175_14405	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
N175_14410	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
N175_14415	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
N175_14420	ENOG4105PM1	preprotein translocase subunit SecE
N175_14425	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
N175_14450	ENOG4105CS9	pantothenic acid kinase
N175_14455	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
N175_14460	ENOG4105D4A	Cell wall formation (By similarity)
N175_14470	ENOG4105JIM	Phosphatidylserine synthase
N175_14580	ENOG4105VFU	Rna-binding protein
N175_14645	ENOG41090WB	Transposase is3 is911
N175_14705	ENOG4108ZJT	translation initiation factor, Sui1
N175_14720	ENOG4105CPF	Cell wall formation (By similarity)
N175_14730	ENOG4105CD5	CoA-binding domain protein
N175_14735	ENOG4105CWB	LysR family transcriptional Regulator
N175_14765	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
N175_14775	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
N175_14780	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
N175_14795	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
N175_14800	ENOG4105VEQ	Cold shock protein
N175_14810	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_14825	ENOG410848D	S4 domain protein YaaA
N175_14830	ENOG4105CYM	Glutathione S-transferase
N175_14845	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
N175_14850	ENOG4105C5H	ABC transporter
N175_14865	ENOG4105KA0	thioesterase Superfamily protein
N175_14875	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
N175_14885	ENOG4105DU1	integral membrane protein, terc
N175_14890	ENOG4105CGH	5'-nucleotidase
N175_14895	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
N175_14900	ENOG4108UQ5	membrane protein YcdZ
N175_14905	ENOG4105DUM	transcriptional regulator, lysR family
N175_14910	ENOG4105TMB	Formate nitrite transporter
N175_14920	ENOG4105DUX	Transporter
N175_14930	ENOG4108K85	Transcriptional regulator
N175_14935	ENOG4105NXH	GreA GreB family elongation factor
N175_14940	ENOG4105PAD	Hydrolase
N175_14945	ENOG4105DZ0	fad dependent oxidoreductase
N175_14950	ENOG4108Z4U	Ferredoxin
N175_14965	ENOG4105CKU	formyltetrahydrofolate synthetase
N175_14970	ENOG4105E0X	reductase
N175_14980	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
N175_14985	ENOG4105D06	uba thif-type nad fad binding protein
N175_14990	ENOG4105KHC	sulfurtransferase
N175_15005	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
N175_15025	ENOG4108V1T	peptidylprolyl cis-trans isomerase
N175_15030	ENOG4107VXZ	Hydrolase
N175_15035	ENOG4108N3W	hemolysin secretion protein
N175_15040	ENOG4108YYC	ycei family
N175_15045	ENOG4105DS1	cytochrome b561
N175_15060	ENOG4108JQ5	ABC transporter
N175_15065	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
N175_15070	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
N175_15075	ENOG4105E43	Extracellular solute-binding protein, family 5
N175_15090	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
N175_15095	ENOG4105CGF	Aromatic amino acid aminotransferase
N175_15100	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
N175_15105	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
N175_15110	ENOG4105BZU	Histidine kinase
N175_15135	ENOG41080HT	Transcriptional regulator, arsr family
N175_15145	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
N175_15150	ENOG4105BZU	Histidine kinase
N175_15160	ENOG4105BZU	Histidine kinase
N175_15170	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
N175_15195	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
N175_15200	ENOG4105E0C	molybdate abc transporter
N175_15205	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
N175_15210	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
N175_15215	ENOG4105WXI	Bacterial OB fold (BOF) protein
N175_15225	ENOG4105BZU	Histidine kinase
N175_15230	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
N175_15240	ENOG4105CF7	AraC family transcriptional regulator
N175_15245	ENOG4108I6A	alcohol dehydrogenase
N175_15250	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
N175_15260	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
N175_15265	ENOG4105CXY	transporter
N175_15270	ENOG4105CA9	Pyruvate kinase
N175_15275	ENOG4105BZU	Histidine kinase
N175_15280	ENOG4108SV3	Tmao reductase system periplasmic protein tort
N175_15285	ENOG4108Z5K	methylglyoxal synthase
N175_15290	ENOG41088T4	Helicase IV
N175_15295	ENOG4105EM2	membrane
N175_15315	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
N175_15325	ENOG4105BZU	Histidine kinase
N175_15330	ENOG4108QGH	periplasmic
N175_15340	ENOG41082IR	Excinuclease ABC C subunit domain protein
N175_15345	ENOG4108YXG	UPF0502 protein
N175_15355	ENOG41090HJ	UPF0265 protein
N175_15365	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
N175_15370	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
N175_15375	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
N175_15380	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
N175_15385	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
N175_15390	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
N175_15395	ENOG4105K63	Thioredoxin
N175_15405	ENOG4105VXR	cytoplasmic protein
N175_15415	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
N175_15430	ENOG4105WZK	nitrite reductase NADPH small subunit
N175_15435	ENOG4107QZF	nitrite reductase NADPH large subunit
N175_15445	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
N175_15450	ENOG4105C26	Dehydrogenase
N175_15455	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
N175_15465	ENOG4108HQS	Glycine betaine
N175_15470	ENOG4108IJ7	Glycine betaine
N175_15485	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
N175_15500	ENOG4105C5W	Aldolase
N175_15510	ENOG4105C1J	atp-dependent rna helicase
N175_15520	ENOG4105E0U	tyrosine-specific transport protein
N175_15525	ENOG4108NVR	Methyl-accepting chemotaxis
N175_15530	ENOG4105CMR	udp-glucose 4-epimerase
N175_15535	ENOG4105E7W	lamb ycsf family protein
N175_15555	ENOG4105CV6	ABC transporter, permease
N175_15560	ENOG4108I0Y	(ABC) transporter
N175_15570	ENOG4105RKW	reductase (By
N175_15585	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
N175_15600	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
N175_15605	ENOG410607W	Transposase
N175_15625	ENOG4107RE1	Inosine-guanosine kinase
N175_15630	ENOG4105BZU	Histidine kinase
N175_15645	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_15650	ENOG4105CYW	agmatinase
N175_15655	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
N175_15665	ENOG4108IJ7	Glycine betaine
N175_15670	ENOG4108HQS	Glycine betaine
N175_15675	ENOG4105GIJ	Glycine betaine
N175_15695	ENOG4105CJW	magnesium transporter
N175_15700	ENOG4105CZK	Aspartate kinase
N175_15705	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
N175_15710	ENOG4108JPW	Aminotransferase
N175_15715	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
N175_15725	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
N175_15730	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
N175_15765	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_15785	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_15790	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
N175_15825	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
N175_15835	ENOG4105N1F	Hnh endonuclease
N175_15840	ENOG4105VRT	cytoplasmic protein
N175_15845	ENOG4105E0M	Sulfatase
N175_15855	ENOG41080IJ	Diacylglycerol kinase
N175_15860	ENOG4105CPQ	Dehydrogenase
N175_15865	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
N175_15870	ENOG4105EXG	Transcriptional regulator
N175_15875	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
N175_15885	ENOG4105CXY	transporter
N175_15890	ENOG4108KX4	response regulator
N175_15900	ENOG4105CXY	transporter
N175_15915	ENOG4108ESY	Metal dependent phosphohydrolase
N175_15935	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
N175_15940	ENOG41082YX	Transcriptional regulator, arsr family
N175_15945	ENOG4105D6J	arsenicaL-resistance protein
N175_15960	ENOG4105CHH	sulfate transporter
N175_15975	ENOG4105BZU	Histidine kinase
N175_15980	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
N175_15985	ENOG4105C5I	Dehydrogenase
N175_16015	ENOG4105VEQ	Cold shock protein
N175_16020	ENOG4108VWS	Yaeq family
N175_16030	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
N175_16035	ENOG4108JUA	Transcriptional regulator
N175_16045	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
N175_16050	ENOG4105D9N	nucleoside
N175_16055	ENOG4105QVC	MOSC domain-containing protein
N175_16060	ENOG4105EKE	dihydroorotase
N175_16065	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
N175_16070	ENOG4105CKW	Inner membrane protein yedI
N175_16075	ENOG4108ESY	Metal dependent phosphohydrolase
N175_16100	ENOG4108WQH	regulatoR
N175_16130	ENOG4105BZU	Histidine kinase
N175_16135	ENOG4105E98	transcriptional regulator DeoR family
N175_16140	ENOG4105VJY	transcriptional regulator
N175_16145	ENOG4105NNS	Autoinducer synthesis protein
N175_16160	ENOG4105EG2	ABC transporter, permease
N175_16165	ENOG4105D56	permease protein
N175_16170	ENOG4107FKK	extracellular solute-binding protein family 1
N175_16175	ENOG4108IJ9	(ABC) transporter
N175_16180	ENOG41086KC	Transcriptional regulator
N175_16185	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
N175_16190	ENOG4107R88	Chemotaxis protein (CheV)
N175_16195	ENOG4105MSB	protein, conserved in bacteria
N175_16200	ENOG4106TD9	Diguanylate cyclase
N175_16215	ENOG4105BZU	Histidine kinase
N175_16235	ENOG4108K0B	C-di-gmp phosphodiesterase
N175_16245	ENOG4105EUB	pirin domain protein
N175_16255	ENOG4105NBK	UPF0345 protein
N175_16265	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
N175_16270	ENOG4105CDA	abc transporter atp-binding protein
N175_16275	ENOG4105E5Q	amino acid AbC transporter
N175_16280	ENOG4106TNF	Periplasmic binding protein
N175_16285	ENOG4105DRP	amino acid AbC transporter
N175_16310	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
N175_16320	ENOG4108SXK	Transporter Drug Metabolite Exporter family
N175_16340	ENOG4105E5M	Multidrug resistance protein D
N175_16345	ENOG4105EQ2	LysR family Transcriptional regulator
N175_16355	ENOG4105DR5	peptidase
N175_16365	ENOG4105CHH	sulfate transporter
N175_16370	ENOG4105DWD	nucleoside recognition domain protein
N175_16385	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
N175_16390	ENOG4105E2Z	phosphate ABC transporter (Permease
N175_16395	ENOG4105C8U	phosphate abc transporter
N175_16400	ENOG4105CVA	phosphate
N175_16410	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
N175_16415	ENOG4108HK0	-acetyltransferase
N175_16430	ENOG4105D4Y	metalloprotease
N175_16440	ENOG4105EIF	outer membrane protein W
N175_16450	ENOG4108M1A	Chitin-binding protein
N175_16455	ENOG4105CXY	transporter
N175_16460	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
N175_16470	ENOG4107FQX	Alpha-acetolactate decarboxylase
N175_16475	ENOG4105C7K	acetolactate synthase
N175_16495	ENOG4105CC0	LysR family Transcriptional regulator
N175_16500	ENOG4105DAA	L-lactate
N175_16505	ENOG4105DMF	Dehydrogenase
N175_16520	ENOG4108V1U	phospholipid-binding protein
N175_16525	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
N175_16535	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
N175_16550	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
N175_16560	ENOG41069D7	Methyl-accepting chemotaxis
N175_16565	ENOG4105ETE	Transcriptional regulator (LacI family
N175_16575	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
N175_16580	ENOG4105DRS	transport system, permease
N175_16595	ENOG41060NJ	transcriptional regulator
N175_16600	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
N175_16620	ENOG4105E5W	Transporter
N175_16625	ENOG4108NVR	Methyl-accepting chemotaxis
N175_16630	ENOG4105DAN	ATP-dependent protease
N175_16640	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
N175_16660	ENOG4105CC0	LysR family Transcriptional regulator
N175_16675	ENOG4105ETE	Transcriptional regulator (LacI family
N175_16680	ENOG4108RVA	ribokinase
N175_16685	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
N175_16690	ENOG4105CNN	ABC, transporter
N175_16695	ENOG4105C2J	ABC transporter
N175_16700	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
N175_16720	ENOG4105CS6	Rhs element vgr protein
N175_16725	ENOG4108WC9	type VI secretion system effector, hcp1 family
N175_16735	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
N175_16740	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
N175_16745	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
N175_16750	ENOG41061ZR	Transcriptional regulator
N175_16755	ENOG4108YYI	Protein of unknown function (DUF2810)
N175_16760	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_16770	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_16775	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
N175_16795	ENOG4107RGH	Aldehyde dehydrogenase
N175_16800	ENOG4105EW9	transcriptional regulator AsnC family
N175_16805	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_16815	ENOG4105CK7	Sodium proline symporter
N175_16825	ENOG4105C26	Dehydrogenase
N175_16840	ENOG4105E6M	Sulphatase-modifying factor protein
N175_16850	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
N175_16855	ENOG4107QZV	Type I secretion membrane fusion protein
N175_16870	ENOG4108JJA	ABC, transporter
N175_16880	ENOG4105BZU	Histidine kinase
N175_16890	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_16895	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
N175_16905	ENOG4105BZU	Histidine kinase
N175_16910	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_16915	ENOG4108V3W	Chemotaxis protein, CheW
N175_16920	ENOG4108V3W	Chemotaxis protein, CheW
N175_16925	ENOG4105CBS	Chea signal transduction histidine kinase
N175_16930	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
N175_16940	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
N175_16945	ENOG4107RUE	extracellular solute-binding protein family 1
N175_16950	ENOG410607W	Transposase
N175_16960	ENOG4106RMF	ParB family
N175_16975	ENOG410607W	Transposase
N175_17000	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
N175_17005	ENOG4105C44	Serine transporter
N175_17035	ENOG4105HEI	LysR family (Transcriptional regulator
N175_17040	ENOG4108RYK	Nad-dependent epimerase dehydratase
N175_17050	ENOG410901E	Membrane
N175_17065	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
N175_17070	ENOG4105D03	DNA-3-methyladenine glycosylase II
N175_17075	ENOG410607W	Transposase
N175_17100	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
N175_17110	ENOG4105DR5	peptidase
N175_17120	ENOG4105CTS	PTS system mannitol-specific
N175_17125	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
N175_17130	ENOG4105E61	Mannitol repressor protein
N175_17135	ENOG4105EP9	oxidoreductase
N175_17140	ENOG4105DN9	Na H antiporter
N175_17145	ENOG4105CK2	sodium dicarboxylate symporter
N175_17150	ENOG4108VGI	doxx family
N175_17175	ENOG4105J12	Multidrug resistance protein mdtN
N175_17180	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
N175_17185	ENOG4108MJ5	VirK protein
N175_17190	ENOG4108M8H	domain protein
N175_17195	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
N175_17200	ENOG41082J7	Rhodanese domain protein
N175_17205	ENOG4107QWP	ABC-2 type transporter
N175_17210	ENOG4105CJ1	ABC, transporter
N175_17225	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
N175_17235	ENOG4105F38	ABC transporter, permease
N175_17255	ENOG4105C1J	atp-dependent rna helicase
N175_17265	ENOG4107VXZ	Hydrolase
N175_17275	ENOG41076CZ	activating enzyme
N175_17280	ENOG4105G0K	glycine radical enzyme YjjI family
N175_17290	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
N175_17295	ENOG4108WUH	Transcriptional regulator, TetR family
N175_17310	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
N175_17320	ENOG4105D3G	Pseudouridine synthase
N175_17385	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
N175_17390	ENOG4108JUB	Transcriptional regulator
N175_17415	ENOG4105CS6	Rhs element vgr protein
N175_17475	ENOG4105C8P	)-transporter
N175_17480	ENOG4108Q67	UPF0319 protein
N175_17490	ENOG4105FDP	GntR family transcriptional regulator
N175_17495	ENOG4105CZV	ABC transporter
N175_17505	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_17520	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_17535	ENOG4105EYK	Phosphatidylglycerophosphatase B
N175_17540	ENOG4108UH6	UPF0754 membrane protein
N175_17545	ENOG4105BZ1	(ABC) transporter
N175_17565	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
N175_17575	ENOG4108K4B	hydrolase
N175_17610	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
N175_17625	ENOG4107FKK	extracellular solute-binding protein family 1
N175_17635	ENOG4105CG3	alpha amylase, catalytic region
N175_17645	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
N175_17670	ENOG4105D6U	Sodium Glutamate Symporter
N175_17675	ENOG4105YE1	PilZ domain
N175_17695	ENOG4105EFX	secretion protein, HlyD family
N175_17700	ENOG4105KK7	inner membrane protein YiaW
N175_17705	ENOG4106TD9	Diguanylate cyclase
N175_17720	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
N175_17725	ENOG4107SEY	Conserved Protein
N175_17730	ENOG4108XDN	Transcriptional regulator
N175_17735	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
N175_17740	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
N175_17750	ENOG4105C1J	atp-dependent rna helicase
N175_17800	ENOG4105MUZ	Protein of unknown function DUF2620
N175_17820	ENOG4108M0H	Extracellular lipase
N175_17825	ENOG4108M0H	Extracellular lipase
N175_17830	ENOG4108M0H	Extracellular lipase
N175_17835	ENOG4108M0H	Extracellular lipase
N175_17850	ENOG4107T9C	Alpha amylase catalytic region
N175_17855	ENOG4107RGM	aldo keto reductase
N175_17865	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
N175_17870	ENOG4105D60	lipoprotein releasing system transmembrane protein
N175_17890	ENOG4108VAC	response regulator
N175_17905	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
N175_17915	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
N175_17920	ENOG4105BZU	Histidine kinase
N175_17925	ENOG4108NVR	Methyl-accepting chemotaxis
N175_17930	ENOG4105DVH	amino acid
N175_17945	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
N175_17955	ENOG4105BZU	Histidine kinase
N175_17970	ENOG4107V40	secretion protein, HlyD family
N175_17975	ENOG4108IJF	Heavy metal efflux pump, CzcA
N175_17985	ENOG4107YWA	deoxycytidylate deaminase
N175_17995	ENOG4105EE0	oxidoreductase
N175_18005	ENOG4108UW5	maltose o-acetyltransferase
N175_18020	ENOG4105DUM	transcriptional regulator, lysR family
N175_18035	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
N175_18040	ENOG4105MIR	Phenylalanine 4-monooxygenase
N175_18045	ENOG41090A4	Pterin carbinolamine dehydratase
N175_18055	ENOG4105C8Q	Methyl-accepting chemotaxis
N175_18060	ENOG4105UQX	Mate efflux family protein
N175_18065	ENOG4108AHD	Transcriptional regulator
N175_18070	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
N175_18075	ENOG4105BZU	Histidine kinase
N175_18085	ENOG4105E5M	Multidrug resistance protein D
N175_18095	ENOG4105R8A	Heat shock protein
N175_18105	ENOG4105EW9	transcriptional regulator AsnC family
N175_18110	ENOG4105KUU	lipolytic protein G-D-S-L family
N175_18115	ENOG4106M3D	hemolysin
N175_18120	ENOG4107IFA	Lipase (EC 3.1.1.3)
N175_18130	ENOG4107G87	m6 family metalloprotease domain protein
N175_18145	ENOG4105KXC	Collagenase
N175_18160	ENOG4105DHS	permease protein
N175_18165	ENOG4105CM4	permease protein
N175_18170	ENOG4108IPW	abc transporter atp-binding protein
N175_18175	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
N175_18180	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
N175_18185	ENOG4108UDW	Transcriptional regulator, luxr family
N175_18220	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
N175_18240	ENOG4105EE5	Membrane protein terC
N175_18250	ENOG4105NF4	modulator of drug activity
N175_18255	ENOG4105CV8	reductase
N175_18260	ENOG4105JQN	Transcriptional regulator
N175_18285	ENOG4105EFX	secretion protein, HlyD family
N175_18300	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N175_18305	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
N175_18310	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
N175_18320	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
N175_18335	ENOG4107RAN	Peptidase, M16
N175_18345	ENOG4105DM4	PTS System
N175_18350	ENOG4105DE4	1-phosphofructokinase
N175_18355	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
N175_18360	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
N175_18365	ENOG4107RFY	SbcCD D subunit
N175_18370	ENOG4105EYH	Exonuclease
N175_18375	ENOG4108MGY	Histidine kinase
N175_18380	ENOG4107KBT	8-Amino-7-oxononanoate synthase
N175_18390	ENOG4105CMQ	Chloride channel
N175_18395	ENOG4105CKI	cobalamin synthesis protein
N175_18400	ENOG4105C19	ABC transporter
N175_18410	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
N175_18425	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
N175_18460	ENOG410787A	Pts system, glucitol sorbitol-specific
N175_18465	ENOG4105DZY	Pts system, glucitol sorbitol-specific
N175_18470	ENOG4105VI0	Pts system, glucitol sorbitol-specific
N175_18475	ENOG4107QMF	Sorbitol-6-phosphate dehydrogenase
N175_18480	ENOG4105J92	DNA-binding transcriptional activator GutM
N175_18485	ENOG410804X	Transcriptional regulator
N175_18490	ENOG410787A	Pts system, glucitol sorbitol-specific
N175_18495	ENOG4105DZY	Pts system, glucitol sorbitol-specific
N175_18500	ENOG4105VI0	Pts system, glucitol sorbitol-specific
N175_18505	ENOG4108IJ9	(ABC) transporter
N175_18515	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
N175_18525	ENOG4107FKK	extracellular solute-binding protein family 1
N175_18535	ENOG4105EG2	ABC transporter, permease
N175_18540	ENOG4108IUK	alpha amylase, catalytic
N175_18560	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
N175_18565	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
N175_18575	ENOG4105CUW	cytochrome C-TYPE protein
N175_18585	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
N175_18600	ENOG4105BZU	Histidine kinase
N175_18605	ENOG4105WH1	Two component transcriptional regulator luxr family
N175_18610	ENOG4105CEE	C4-dicarboxylate transporter
N175_18635	ENOG4105CVA	phosphate
N175_18650	ENOG4105C1J	atp-dependent rna helicase
N175_18655	ENOG4105C22	threonyL-tRNA synthetase
N175_18660	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
N175_18665	ENOG41082NX	50s ribosomal protein l35
N175_18670	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
N175_18695	ENOG4105I08	Pseudouridine synthase
N175_18700	ENOG4108WF3	methyltransferase
N175_18940	ENOG4105QNF	Outer membrane lipoprotein
N175_19245	ENOG4108IPW	abc transporter atp-binding protein
N175_19250	ENOG4105WQI	isochorismatase
N175_19255	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
N175_19260	ENOG4105E4F	Isochorismate synthase
N175_19270	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
N175_19415	ENOG4108JJB	ABC transporter
N175_19420	ENOG4105BZ1	(ABC) transporter
N175_19450	ENOG410607W	Transposase
N175_19460	ENOG4105VUH	addiction module killer protein
N175_19485	ENOG4107QJE	Chromosome Partitioning Protein
N175_19505	ENOG410607W	Transposase