locus-tag	class	description
CG015_00030	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CG015_00035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CG015_00040	COG0438	transferase activity, transferring glycosyl groups
CG015_00050	COG0438	transferase activity, transferring glycosyl groups
CG015_00055	COG1216	Glycosyl transferase, family 2
CG015_00065	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CG015_00070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CG015_00110	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CG015_00130	COG5433	transposase activity
CG015_00135	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CG015_00135	COG2755	lipolytic protein G-D-S-L family
CG015_00140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CG015_00145	COG0110	maltose O-acetyltransferase activity
CG015_00150	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CG015_00160	COG0438	transferase activity, transferring glycosyl groups
CG015_00165	COG0438	transferase activity, transferring glycosyl groups
CG015_00225	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CG015_00240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG015_00255	COG3307	-O-antigen
CG015_00265	COG0859	PFAM glycosyl transferase family 9
CG015_00280	COG1519	Transferase
CG015_00310	COG3642	lipopolysaccharide core region biosynthetic process
CG015_00315	COG0859	PFAM glycosyl transferase family 9
CG015_00320	COG0463	Glycosyl transferase, family 2
CG015_00325	COG0859	PFAM glycosyl transferase family 9
CG015_00330	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CG015_00335	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CG015_00345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CG015_00360	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CG015_00365	COG1309	transcriptional regulator
CG015_00370	COG1560	Kdo2-lipid A biosynthetic process
CG015_00375	COG1560	Kdo2-lipid A biosynthetic process
CG015_00385	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CG015_00390	COG1561	YicC-like family, N-terminal region
CG015_00395	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CG015_00400	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
CG015_00405	COG3051	citrate lyase alpha subunit
CG015_00410	COG2301	Belongs to the HpcH HpaI aldolase family
CG015_00415	COG3052	prosthetic group binding
CG015_00420	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CG015_00435	COG0511	ligase activity, forming carbon-carbon bonds
CG015_00435	COG5016	pyruvate
CG015_00440	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CG015_00450	COG4565	transcriptional regulatory protein
CG015_00465	COG0612	Peptidase, M16
CG015_00485	COG1120	ATPase activity
CG015_00490	COG4774	siderophore transport
CG015_00495	COG1132	(ABC) transporter
CG015_00500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG015_00500	COG1263	PTS System
CG015_00505	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CG015_00525	COG0514	ATP-dependent DNA helicase (RecQ)
CG015_00530	COG2962	Rard protein
CG015_00535	COG0405	Gamma-glutamyltransferase
CG015_00545	COG1280	lysine exporter protein (LysE YggA)
CG015_00550	COG0210	DNA helicase
CG015_00555	COG0339	signal peptide processing
CG015_00560	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CG015_00565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CG015_00675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG015_00730	COG1309	transcriptional regulator
CG015_00735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG015_00740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG015_00745	COG2960	long-chain fatty acid transporting porin activity
CG015_00755	COG0583	DNA-binding transcription factor activity
CG015_00760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CG015_00785	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CG015_00790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG015_00790	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG015_00800	COG0084	hydrolase, TatD family'
CG015_00805	COG0805	protein transport
CG015_00810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CG015_00820	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CG015_00835	COG1322	Protein conserved in bacteria
CG015_00855	COG2160	L-arabinose isomerase activity
CG015_00865	COG1069	ribulokinase activity
CG015_00870	COG1879	ABC-type sugar transport system periplasmic component
CG015_00875	COG1129	ABC transporter
CG015_00880	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG015_00885	COG2081	HI0933 family
CG015_00900	COG1528	Iron-storage protein
CG015_00905	COG0589	response to stress
CG015_00910	COG0697	spore germination
CG015_00920	COG0742	ribosomal rna small subunit methyltransferase
CG015_00925	COG1522	sequence-specific DNA binding
CG015_00945	COG0006	proline dipeptidase activity
CG015_00945	COG0006	proline dipeptidase activity
CG015_00950	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CG015_00960	COG2104	thiamine diphosphate biosynthetic process
CG015_00965	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG015_00970	COG0352	thiamine-phosphate diphosphorylase activity
CG015_01050	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CG015_01055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG015_01060	COG1739	Uncharacterized protein family UPF0029
CG015_01070	COG0183	Belongs to the thiolase family
CG015_01075	COG0583	DNA-binding transcription factor activity
CG015_01080	COG2814	Major facilitator Superfamily
CG015_01090	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CG015_01095	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CG015_01100	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CG015_01105	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CG015_01110	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CG015_01115	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CG015_01125	COG0356	it plays a direct role in the translocation of protons across the membrane
CG015_01130	COG3312	ion transport
CG015_01135	COG1475	DNA binding
CG015_01140	COG1192	Involved in chromosome partitioning
CG015_01150	COG0445	tRNA wobble uridine modification
CG015_01155	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CG015_01165	COG0706	membrane insertase activity
CG015_01170	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CG015_01185	COG1126	abc transporter atp-binding protein
CG015_01205	COG0592	DNA-directed DNA polymerase activity
CG015_01210	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CG015_01215	COG0187	DNA topoisomerase II activity
CG015_01230	COG0071	Belongs to the small heat shock protein (HSP20) family
CG015_01235	COG3977	Valine--pyruvate aminotransferase
CG015_01245	COG0752	glycyl-tRNA synthetase alpha subunit
CG015_01250	COG2119	membrane
CG015_01275	COG0604	alcohol dehydrogenase
CG015_01285	COG0129	dihydroxy-acid dehydratase activity
CG015_01290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG015_01295	COG3978	acetolactate synthase activity
CG015_01305	COG0606	chelatase, subunit chli
CG015_01315	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CG015_01320	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG015_01335	COG3084	Protein conserved in bacteria
CG015_01345	COG1272	protein, Hemolysin III
CG015_01355	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG015_01360	COG0569	domain protein
CG015_01365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CG015_01365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG015_01370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CG015_01375	COG0242	peptide deformylase activity
CG015_01380	COG1652	LysM domain
CG015_01385	COG0758	DNA mediated transformation
CG015_01390	COG2922	Belongs to the Smg family
CG015_01395	COG0551	DNA topoisomerase type I activity
CG015_01400	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CG015_01405	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CG015_01410	COG0009	L-threonylcarbamoyladenylate synthase
CG015_01415	COG0408	coproporphyrinogen oxidase activity
CG015_01420	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CG015_01430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CG015_01460	COG3071	HemY protein
CG015_01465	COG2959	enzyme of heme biosynthesis
CG015_01470	COG1587	Uroporphyrinogen-III synthase
CG015_01480	COG3072	Adenylate cyclase
CG015_01495	COG0019	diaminopimelate decarboxylase activity
CG015_01510	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CG015_01515	COG1011	Hydrolase
CG015_01530	COG0561	phosphatase activity
CG015_01535	COG2267	carboxylic ester hydrolase activity
CG015_01540	COG1280	lysine exporter protein (LysE YggA)
CG015_01545	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CG015_01550	COG0783	Belongs to the Dps family
CG015_01580	COG2095	MarC family integral membrane protein
CG015_01590	COG0742	ribosomal rna small subunit methyltransferase
CG015_01595	COG0552	protein localization to endoplasmic reticulum
CG015_01600	COG2884	Cell division ATP-binding protein ftsE
CG015_01605	COG2177	Part of the ABC transporter FtsEX involved in
CG015_01610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CG015_01620	COG0705	Rhomboid family
CG015_01625	COG1580	Controls the rotational direction of flagella during chemotaxis
CG015_01630	COG3161	chorismate lyase activity
CG015_01640	COG2937	Belongs to the GPAT DAPAT family
CG015_01655	COG0534	Mate efflux family protein
CG015_01675	COG3250	beta-galactosidase activity
CG015_01800	COG4206	TonB-dependent receptor
CG015_01810	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CG015_01855	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CG015_01860	COG3300	MHYT domain
CG015_01860	COG5001	Diguanylate cyclase
CG015_01870	COG3852	Histidine kinase
CG015_01880	COG0174	glutamine synthetase
CG015_01895	COG1490	D-aminoacyl-tRNA deacylase activity
CG015_01900	COG0456	acetyltransferase
CG015_01910	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CG015_01915	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CG015_01920	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CG015_01925	COG3031	protein transport across the cell outer membrane
CG015_01935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CG015_01940	COG1459	type II secretion system
CG015_01945	COG2165	general secretion pathway protein
CG015_01950	COG2165	general secretion pathway protein
CG015_01955	COG2165	general secretion pathway protein
CG015_01960	COG4795	General secretion pathway protein
CG015_01965	COG3156	type II secretion system protein K
CG015_01970	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CG015_01975	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CG015_01985	COG1218	3'(2'),5'-bisphosphate nucleotidase
CG015_01990	COG0494	nUDIX hydrolase
CG015_01995	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CG015_01995	COG0316	Belongs to the HesB IscA family
CG015_02000	COG1040	competence protein
CG015_02005	COG0596	Alpha beta hydrolase
CG015_02015	COG2183	response to ionizing radiation
CG015_02020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CG015_02040	COG0583	DNA-binding transcription factor activity
CG015_02060	COG0745	RESPONSE REGULATOR receiver
CG015_02070	COG2233	PERMEase
CG015_02075	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CG015_02080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CG015_02085	COG1758	RNA polymerase activity
CG015_02090	COG0194	GDP metabolic process
CG015_02095	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CG015_02100	COG0248	Ppx GppA phosphatase
CG015_02110	COG3118	belongs to the thioredoxin family
CG015_02115	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CG015_02125	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CG015_02175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG015_02185	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CG015_02190	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CG015_02190	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CG015_02195	COG1072	(Pantothenic acid kinase))
CG015_02220	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CG015_02225	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CG015_02230	COG0250	Participates in transcription elongation, termination and antitermination
CG015_02240	COG0081	regulation of translation
CG015_02245	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CG015_02250	COG0222	ribosome binding
CG015_02255	COG0085	RNA polymerase activity
CG015_02260	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CG015_02265	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CG015_02270	COG2816	NAD+ diphosphatase activity
CG015_02290	COG4942	peptidase
CG015_02295	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CG015_02310	COG0490	domain, Protein
CG015_02310	COG0471	metal ion transport
CG015_02320	COG1162	GTPase activity
CG015_02325	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CG015_02375	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CG015_02380	COG0802	atpase or kinase
CG015_02390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CG015_02395	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CG015_02400	COG1923	regulation of RNA biosynthetic process
CG015_02405	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CG015_02410	COG0330	HflC and HflK could
CG015_02415	COG0330	HflC and HflK could
CG015_02420	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CG015_02435	COG0545	Peptidyl-prolyl cis-trans isomerase
CG015_02440	COG2964	Protein conserved in bacteria
CG015_02445	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CG015_02450	COG2923	Belongs to the DsrF TusC family
CG015_02465	COG0049	tRNA binding
CG015_02470	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CG015_02475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CG015_02480	COG0360	Binds together with S18 to 16S ribosomal RNA
CG015_02485	COG2965	DNA replication, synthesis of RNA primer
CG015_02495	COG0359	binds to the 23S rRNA
CG015_02505	COG0305	Participates in initiation and elongation during chromosome replication
CG015_02510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CG015_02515	COG0166	Belongs to the GPI family
CG015_02525	COG0735	belongs to the Fur family
CG015_02570	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CG015_02590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CG015_02610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CG015_02620	COG0175	sulfate reduction
CG015_02730	COG0646	methionine synthase
CG015_02730	COG1410	methionine synthase
CG015_02735	COG0527	aspartate kinase activity
CG015_02740	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CG015_02755	COG2239	Acts as a magnesium transporter
CG015_02765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CG015_02780	COG0629	single-stranded DNA binding
CG015_02785	COG2200	EAL domain
CG015_02785	COG2199	diguanylate cyclase activity
CG015_02810	COG3409	Peptidoglycan-binding domain 1 protein
CG015_02810	COG3267	Type II secretory pathway component ExeA
CG015_02820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CG015_02825	COG1459	type II secretion system
CG015_02870	COG1077	Cell shape determining protein MreB Mrl
CG015_02875	COG1792	Involved in formation and maintenance of cell shape
CG015_02880	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CG015_02885	COG0424	maF-like protein
CG015_02890	COG1530	ribonuclease E activity
CG015_02895	COG3164	Protein of unknown function
CG015_02900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CG015_02905	COG0312	modulator of DNA gyrase
CG015_02910	COG2235	arginine
CG015_02930	COG0589	response to stress
CG015_02960	COG0531	amino acid
CG015_02965	COG0142	geranyltranstransferase activity
CG015_02980	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CG015_02985	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CG015_02990	COG2966	Psort location CytoplasmicMembrane, score
CG015_02995	COG3610	response to peptide
CG015_03010	COG2967	ApaG domain
CG015_03020	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CG015_03025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CG015_03030	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CG015_03035	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CG015_03085	COG0741	lytic transglycosylase activity
CG015_03100	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CG015_03105	COG2066	Belongs to the glutaminase family
CG015_03110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CG015_03125	COG1872	DUF167
CG015_03130	COG0762	integral membrane protein
CG015_03135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CG015_03140	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CG015_03155	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CG015_03160	COG1678	Uncharacterized ACR, COG1678
CG015_03170	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CG015_03175	COG2356	endonuclease I
CG015_03180	COG3091	SprT-like family
CG015_03185	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CG015_03190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CG015_03195	COG0583	DNA-binding transcription factor activity
CG015_03200	COG4771	TonB-dependent receptor
CG015_03205	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CG015_03210	COG0126	phosphoglycerate kinase activity
CG015_03220	COG0191	fructose-bisphosphate aldolase activity
CG015_03225	COG0668	transmembrane transport
CG015_03245	COG3706	GGDEF domain
CG015_03250	COG0469	pyruvate kinase activity
CG015_03255	COG1349	DNA-binding transcription factor activity
CG015_03280	COG3501	Rhs element vgr protein
CG015_03320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CG015_03325	COG0358	DNA primase activity
CG015_03330	COG1610	YqeY-like protein
CG015_03350	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CG015_03355	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CG015_03360	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CG015_03365	COG1968	undecaprenyl-diphosphatase activity
CG015_03370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CG015_03375	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CG015_03380	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CG015_03385	COG0585	pseudouridine synthase activity
CG015_03390	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CG015_03395	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CG015_03400	COG4942	peptidase
CG015_03400	COG1388	LysM domain
CG015_03405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CG015_03410	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CG015_03430	COG4208	sulfate ABC transporter
CG015_03435	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CG015_03440	COG1546	Belongs to the CinA family
CG015_03445	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CG015_03450	COG2137	regulation of response to DNA damage stimulus
CG015_03455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CG015_03460	COG0527	aspartate kinase activity
CG015_03515	COG0511	ligase activity, forming carbon-carbon bonds
CG015_03515	COG5016	pyruvate
CG015_03520	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CG015_03525	COG1063	alcohol dehydrogenase
CG015_03530	COG1238	metal cluster binding
CG015_03535	COG0612	Peptidase, M16
CG015_03550	COG4536	flavin adenine dinucleotide binding
CG015_03555	COG4137	Cytochrome C assembly protein
CG015_03560	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CG015_03580	COG0335	large ribosomal subunit rRNA binding
CG015_03585	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CG015_03590	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CG015_03595	COG0237	dephospho-CoA kinase activity
CG015_03605	COG1459	type II secretion system
CG015_03610	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CG015_03620	COG0157	Belongs to the NadC ModD family
CG015_03630	COG0716	FMN binding
CG015_03635	COG4974	Belongs to the 'phage' integrase family
CG015_03640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CG015_03645	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CG015_03650	COG2186	Transcriptional regulator
CG015_03655	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CG015_03660	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG015_03665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CG015_03680	COG0288	reversible hydration of carbon dioxide
CG015_03685	COG0659	secondary active sulfate transmembrane transporter activity
CG015_03690	COG1131	(ABC) transporter
CG015_03695	COG0842	Transport permease protein
CG015_03700	COG0583	DNA-binding transcription factor activity
CG015_03705	COG1486	melibiose metabolic process
CG015_03710	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CG015_03720	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CG015_03730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CG015_03735	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CG015_03740	COG1489	DNA binding
CG015_03745	COG1643	Atp-dependent helicase
CG015_03750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG015_03755	COG1752	Esterase of the alpha-beta hydrolase superfamily
CG015_03760	COG1049	propionate catabolic process, 2-methylcitrate cycle
CG015_03765	COG1929	Belongs to the glycerate kinase type-1 family
CG015_03770	COG2610	gluconate transmembrane transporter activity
CG015_03775	COG3835	regulator
CG015_03790	COG0004	ammonium transporteR
CG015_03795	COG1840	ABC-type Fe3 transport system, periplasmic component
CG015_03810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG015_03825	COG2971	BadF BadG BcrA BcrD
CG015_03835	COG4608	Belongs to the ABC transporter superfamily
CG015_03840	COG0444	Belongs to the ABC transporter superfamily
CG015_03845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG015_03870	COG0628	permease
CG015_03875	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CG015_03880	COG0316	Belongs to the HesB IscA family
CG015_03895	COG0739	heme binding
CG015_03900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CG015_03910	COG2239	Acts as a magnesium transporter
CG015_03915	COG2027	D-alanyl-D-alanine carboxypeptidase
CG015_03920	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CG015_03925	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CG015_03930	COG1534	Rna-binding protein
CG015_03940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CG015_03945	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CG015_03950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG015_03955	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CG015_03970	COG0779	Required for maturation of 30S ribosomal subunits
CG015_03975	COG0195	Participates in both transcription termination and antitermination
CG015_03990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CG015_04010	COG1846	Transcriptional regulator
CG015_04040	COG3153	acetyltransferase
CG015_04065	COG0513	Belongs to the DEAD box helicase family
CG015_04085	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CG015_04090	COG2204	response regulator
CG015_04100	COG0667	Aldo Keto reductase
CG015_04105	COG3066	DNA modification
CG015_04110	COG0494	nUDIX hydrolase
CG015_04115	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CG015_04120	COG0730	response to heat
CG015_04130	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CG015_04135	COG1283	sodium-dependent phosphate transmembrane transporter activity
CG015_04140	COG0583	DNA-binding transcription factor activity
CG015_04145	COG0640	Transcriptional regulator
CG015_04155	COG0728	peptidoglycan biosynthetic process
CG015_04160	COG0196	riboflavin kinase activity
CG015_04170	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CG015_04175	COG1047	Peptidyl-prolyl cis-trans
CG015_04185	COG1966	Carbon starvation protein
CG015_04195	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CG015_04200	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CG015_04205	COG1472	Belongs to the glycosyl hydrolase 3 family
CG015_04210	COG3279	Response regulator of the LytR AlgR family
CG015_04215	COG3275	phosphorelay sensor kinase activity
CG015_04220	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CG015_04225	COG1605	Chorismate mutase
CG015_04225	COG0287	Prephenate dehydrogenase
CG015_04235	COG0488	(ABC) transporter
CG015_04250	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CG015_04255	COG5001	Diguanylate cyclase
CG015_04260	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CG015_04265	COG0077	Prephenate dehydratase
CG015_04265	COG1605	Chorismate mutase
CG015_04270	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CG015_04275	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CG015_04280	COG0564	pseudouridine synthase activity
CG015_04290	COG0542	response to heat
CG015_04335	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CG015_04350	COG0745	RESPONSE REGULATOR receiver
CG015_04355	COG5002	protein histidine kinase activity
CG015_04365	COG0248	Ppx GppA phosphatase
CG015_04370	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CG015_04380	COG0581	inorganic phosphate transmembrane transporter activity
CG015_04385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CG015_04390	COG0704	Plays a role in the regulation of phosphate uptake
CG015_04395	COG3142	Participates in the control of copper homeostasis
CG015_04400	COG0450	alkyl hydroperoxide reductase
CG015_04405	COG0583	DNA-binding transcription factor activity
CG015_04410	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CG015_04420	COG0517	IMP dehydrogenase activity
CG015_04425	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CG015_04435	COG1862	Preprotein translocase
CG015_04440	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG015_04445	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG015_04450	COG0483	inositol monophosphate 1-phosphatase activity
CG015_04455	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CG015_04460	COG1959	2 iron, 2 sulfur cluster binding
CG015_04470	COG0822	iron-sulfur transferase activity
CG015_04475	COG0316	Belongs to the HesB IscA family
CG015_04485	COG0443	Heat shock 70 kDa protein
CG015_04490	COG0633	Ferredoxin
CG015_04495	COG2975	iron-sulfur cluster assembly
CG015_04500	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CG015_04515	COG1426	Protein conserved in bacteria
CG015_04520	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CG015_04525	COG0124	histidyl-tRNA synthetase
CG015_04530	COG2976	Protein conserved in bacteria
CG015_04535	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CG015_04540	COG1160	GTP binding
CG015_04560	COG0516	GMP reductase activity
CG015_04560	COG0517	IMP dehydrogenase activity
CG015_04565	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CG015_04565	COG0519	Catalyzes the synthesis of GMP from XMP
CG015_04570	COG0351	phosphomethylpyrimidine kinase
CG015_04580	COG1584	GPR1 FUN34 yaaH family protein
CG015_04585	COG1115	amino acid carrier protein
CG015_04590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG015_04605	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CG015_04610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG015_04610	COG3711	transcriptional antiterminator
CG015_04625	COG3964	amidohydrolase
CG015_04655	COG0556	nucleotide-excision repair
CG015_04675	COG2610	gluconate transmembrane transporter activity
CG015_04680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG015_04685	COG3622	Belongs to the hyi family
CG015_04690	COG0235	Class ii aldolase
CG015_04695	COG3395	kinase activity
CG015_04700	COG2084	Dehydrogenase
CG015_04705	COG1349	DNA-binding transcription factor activity
CG015_04720	COG2867	negative regulation of translational initiation
CG015_04725	COG2914	Belongs to the UPF0125 (RnfH) family
CG015_04730	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CG015_04735	COG0497	DNA recombination
CG015_04745	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CG015_04750	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CG015_04755	COG0443	Heat shock 70 kDa protein
CG015_04760	COG0484	heat shock protein binding
CG015_04790	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CG015_04795	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CG015_04800	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CG015_04805	COG0583	DNA-binding transcription factor activity
CG015_04810	COG0590	tRNA wobble adenosine to inosine editing
CG015_04815	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CG015_04825	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CG015_04825	COG0047	phosphoribosylformylglycinamidine synthase activity
CG015_04845	COG2979	Protein of unknown function (DUF533)
CG015_04850	COG0442	prolyl-tRNA aminoacylation
CG015_04855	COG1720	tRNA m6t6A37 methyltransferase activity
CG015_04865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CG015_04895	COG3098	single-species biofilm formation
CG015_04900	COG0564	pseudouridine synthase activity
CG015_04905	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CG015_04910	COG0142	geranyltranstransferase activity
CG015_04920	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CG015_04930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CG015_04930	COG0301	tRNA thio-modification
CG015_04935	COG0583	DNA-binding transcription factor activity
CG015_04940	COG2363	Small membrane protein
CG015_04950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG015_04955	COG1611	Belongs to the LOG family
CG015_04960	COG3706	GGDEF domain
CG015_04980	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CG015_04985	COG1464	Belongs to the NlpA lipoprotein family
CG015_04990	COG2011	ABC-type metal ion transport system permease component
CG015_04995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CG015_05000	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CG015_05015	COG1263	PTS System
CG015_05015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG015_05020	COG0366	Alpha amylase catalytic
CG015_05025	COG0745	RESPONSE REGULATOR receiver
CG015_05030	COG2205	protein histidine kinase activity
CG015_05065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG015_05070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG015_05075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CG015_05080	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CG015_05085	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CG015_05130	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CG015_05170	COG0489	protein tyrosine kinase activity
CG015_05175	COG1596	polysaccharide export
CG015_05195	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CG015_05210	COG0321	lipoyl(octanoyl) transferase activity
CG015_05215	COG2921	Belongs to the UPF0250 family
CG015_05220	COG1686	Belongs to the peptidase S11 family
CG015_05225	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CG015_05230	COG0772	Belongs to the SEDS family
CG015_05235	COG0768	penicillin binding
CG015_05240	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CG015_05245	COG0799	negative regulation of ribosome biogenesis
CG015_05250	COG1466	dna polymerase III delta subunit
CG015_05255	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CG015_05260	COG0495	leucyl-tRNA aminoacylation
CG015_05265	COG2888	peptidyl-tyrosine sulfation
CG015_05270	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CG015_05285	COG1702	phosphate starvation-inducible protein PhoH
CG015_05290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CG015_05295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CG015_05300	COG2190	(PTS) system
CG015_05305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CG015_05310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG015_05315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG015_05320	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CG015_05325	COG3115	cell septum assembly
CG015_05345	COG0789	Transcriptional regulator
CG015_05355	COG0330	HflC and HflK could
CG015_05365	COG3118	belongs to the thioredoxin family
CG015_05370	COG1090	epimerase
CG015_05375	COG0622	Phosphoesterase
CG015_05395	COG0326	Molecular chaperone. Has ATPase activity
CG015_05405	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CG015_05410	COG3104	oligopeptide transport
CG015_05420	COG0367	asparagine synthase
CG015_05425	COG4651	solute:proton antiporter activity
CG015_05425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CG015_05430	COG1940	carbohydrate kinase activity
CG015_05430	COG1846	Transcriptional regulator
CG015_05435	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CG015_05440	COG1263	PTS System
CG015_05440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG015_05440	COG2190	(PTS) system
CG015_05445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CG015_05465	COG0285	dihydrofolate synthase activity
CG015_05470	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CG015_05475	COG1286	toxin biosynthetic process
CG015_05480	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CG015_05485	COG2056	Na+-H+ antiporter family
CG015_05490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CG015_05500	COG0346	lactoylglutathione lyase activity
CG015_05505	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CG015_05520	COG4658	electron transport chain
CG015_05525	COG4656	Part of a membrane complex involved in electron transport
CG015_05530	COG2878	Part of a membrane complex involved in electron transport
CG015_05535	COG4657	Part of a membrane complex involved in electron transport
CG015_05545	COG1629	transport
CG015_05545	COG4774	siderophore transport
CG015_05550	COG2382	esterase
CG015_05570	COG1535	isochorismatase
CG015_05570	COG3433	isochorismatase activity
CG015_05575	COG1021	2,3-dihydroxybenzoate-AMP ligase
CG015_05580	COG1169	isochorismate synthase
CG015_05585	COG1028	Short-chain dehydrogenase reductase Sdr
CG015_05590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CG015_05595	COG5002	protein histidine kinase activity
CG015_05600	COG0745	RESPONSE REGULATOR receiver
CG015_05605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG015_05610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG015_05615	COG0454	-acetyltransferase
CG015_05655	COG0328	RNA-DNA hybrid ribonuclease activity
CG015_05675	COG0419	ATPase involved in DNA repair
CG015_05720	COG2003	Belongs to the UPF0758 family
CG015_05730	COG1518	maintenance of DNA repeat elements
CG015_05760	COG0582	viral genome integration into host DNA
CG015_05770	COG0556	nucleotide-excision repair
CG015_05775	COG2204	response regulator
CG015_05780	COG2198	Histidine kinase
CG015_05785	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CG015_05790	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CG015_05795	COG0521	Mo-molybdopterin cofactor biosynthetic process
CG015_05805	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CG015_05810	COG0314	molybdopterin synthase activity
CG015_05815	COG2199	diguanylate cyclase activity
CG015_05820	COG4109	DRTGG domain
CG015_05830	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CG015_05840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG015_05840	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG015_05845	COG0489	protein tyrosine kinase activity
CG015_05850	COG0572	uridine kinase
CG015_05855	COG2982	Protein involved in outer membrane biogenesis
CG015_05860	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CG015_05865	COG2067	long-chain fatty acid transport protein
CG015_05870	COG2067	long-chain fatty acid transport protein
CG015_05880	COG1595	DNA-templated transcription, initiation
CG015_05890	COG0183	Belongs to the thiolase family
CG015_05895	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG015_05895	COG1024	Enoyl-CoA hydratase
CG015_05900	COG0778	Nitroreductase
CG015_05905	COG0583	DNA-binding transcription factor activity
CG015_05910	COG0745	RESPONSE REGULATOR receiver
CG015_05920	COG2832	Protein of unknown function (DUF454)
CG015_05925	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG015_05935	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CG015_05965	COG2226	methyltransferase
CG015_05980	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG015_05990	COG3139	Protein of unknown function (DUF1315)
CG015_05995	COG0252	asparaginase activity
CG015_06000	COG0616	signal peptide processing
CG015_06005	COG1902	pentaerythritol trinitrate reductase activity
CG015_06005	COG0446	pyridine nucleotide-disulphide oxidoreductase
CG015_06010	COG0788	formyltetrahydrofolate deformylase activity
CG015_06020	COG1199	ATP-dependent helicase activity
CG015_06025	COG1214	PFAM Peptidase M22, glycoprotease
CG015_06040	COG0596	Alpha beta hydrolase
CG015_06045	COG0318	PFAM AMP-dependent synthetase and ligase
CG015_06050	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CG015_06060	COG2894	cell division
CG015_06070	COG3100	YcgL domain-containing protein
CG015_06075	COG2951	lytic endotransglycosylase activity
CG015_06080	COG0583	DNA-binding transcription factor activity
CG015_06085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG015_06110	COG4628	conserved protein (DUF2132)
CG015_06125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CG015_06135	COG0513	Belongs to the DEAD box helicase family
CG015_06145	COG1760	l-serine dehydratase
CG015_06150	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CG015_06155	COG0745	RESPONSE REGULATOR receiver
CG015_06160	COG2205	protein histidine kinase activity
CG015_06165	COG1653	transport
CG015_06175	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CG015_06180	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CG015_06185	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CG015_06190	COG2204	response regulator
CG015_06195	COG4191	Histidine kinase
CG015_06205	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG015_06220	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CG015_06225	COG0776	regulation of translation
CG015_06230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CG015_06235	COG1555	photosystem II stabilization
CG015_06240	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CG015_06245	COG0539	negative regulation of cytoplasmic translation
CG015_06255	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CG015_06260	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CG015_06275	COG0583	DNA-binding transcription factor activity
CG015_06285	COG0686	Belongs to the AlaDH PNT family
CG015_06290	COG1522	sequence-specific DNA binding
CG015_06295	COG1674	ftsk spoiiie
CG015_06305	COG0501	Belongs to the peptidase M48B family
CG015_06315	COG0300	oxidoreductase activity
CG015_06330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CG015_06340	COG2268	Band 7 protein
CG015_06350	COG1032	radical SAM domain protein
CG015_06375	COG0583	DNA-binding transcription factor activity
CG015_06380	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CG015_06390	COG2350	Protein conserved in bacteria
CG015_06395	COG1607	acyl-coa hydrolase
CG015_06425	COG0133	tryptophan synthase activity
CG015_06430	COG0134	indole-3-glycerol-phosphate synthase activity
CG015_06430	COG0135	phosphoribosylanthranilate isomerase activity
CG015_06435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CG015_06440	COG0512	Glutamine amidotransferase of anthranilate synthase
CG015_06445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CG015_06455	COG0613	PHP domain protein
CG015_06460	COG0009	L-threonylcarbamoyladenylate synthase
CG015_06465	COG1187	pseudouridine synthase activity
CG015_06475	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CG015_06480	COG4988	ABC transporter
CG015_06485	COG0492	ferredoxin-NADP+ reductase activity
CG015_06490	COG3706	GGDEF domain
CG015_06490	COG0745	RESPONSE REGULATOR receiver
CG015_06505	COG2949	membrane
CG015_06515	COG0281	malic enzyme
CG015_06535	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CG015_06545	COG1737	Transcriptional regulator
CG015_06550	COG0076	glutamate decarboxylase activity
CG015_06560	COG2431	L-lysine efflux transmembrane transporter activity
CG015_06570	COG3070	regulator of competence-specific genes
CG015_06585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG015_06585	COG4191	Histidine kinase
CG015_06595	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CG015_06600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CG015_06605	COG2915	High frequency lysogenization protein hflD homolog
CG015_06610	COG0482	sulfurtransferase activity
CG015_06620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG015_06625	COG2916	Histone family protein nucleoid-structuring protein H-NS
CG015_06630	COG1757	Na H antiporter
CG015_06640	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CG015_06645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CG015_06650	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CG015_06650	COG0131	Imidazoleglycerol-phosphate dehydratase
CG015_06655	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CG015_06660	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CG015_06665	COG0107	imidazoleglycerol-phosphate synthase activity
CG015_06670	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CG015_06670	COG0140	phosphoribosyl-ATP diphosphatase activity
CG015_06675	COG1187	pseudouridine synthase activity
CG015_06685	COG1278	Cold shock
CG015_06690	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CG015_06695	COG0542	response to heat
CG015_06700	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CG015_06705	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CG015_06710	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CG015_06715	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CG015_06725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CG015_06730	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CG015_06735	COG0297	glycogen (starch) synthase activity
CG015_06755	COG3070	regulator of competence-specific genes
CG015_06760	COG1609	Transcriptional regulator
CG015_06770	COG0745	RESPONSE REGULATOR receiver
CG015_06775	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CG015_06780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CG015_06790	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CG015_06795	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CG015_06810	COG0189	ligase activity
CG015_06810	COG4067	protein conserved in archaea
CG015_06815	COG0500	methyltransferase
CG015_06820	COG4106	trans-aconitate 2-methyltransferase activity
CG015_06825	COG1801	Protein of unknown function DUF72
CG015_06830	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CG015_06835	COG1435	thymidine kinase activity
CG015_06840	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CG015_06865	COG2116	formate transmembrane transporter activity
CG015_06870	COG4459	periplasmic nitrate reductase
CG015_06875	COG3005	denitrification pathway
CG015_06880	COG0243	molybdopterin cofactor binding
CG015_06890	COG1227	inorganic diphosphatase activity
CG015_06900	COG4172	Belongs to the ABC transporter superfamily
CG015_06910	COG4171	peptide transport system, permease
CG015_06915	COG4168	peptide transport system, permease
CG015_06925	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CG015_06930	COG1842	Phage shock protein A
CG015_06945	COG0519	Catalyzes the synthesis of GMP from XMP
CG015_06950	COG0626	cystathionine gamma-synthase activity
CG015_06960	COG0733	neurotransmitter:sodium symporter activity
CG015_06965	COG0564	pseudouridine synthase activity
CG015_06975	COG2200	EAL domain
CG015_06980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CG015_06985	COG4136	ATPase activity
CG015_06990	COG4135	transport system, permease component
CG015_06995	COG4134	Bacterial extracellular solute-binding protein
CG015_07005	COG3313	Fe-S protein
CG015_07015	COG0737	Belongs to the 5'-nucleotidase family
CG015_07025	COG0513	Belongs to the DEAD box helicase family
CG015_07045	COG2205	protein histidine kinase activity
CG015_07060	COG1061	Type III restriction enzyme res subunit
CG015_07065	COG1187	pseudouridine synthase activity
CG015_07070	COG2814	Major facilitator Superfamily
CG015_07080	COG0702	epimerase
CG015_07085	COG0534	Mate efflux family protein
CG015_07090	COG4181	ATPase activity
CG015_07105	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CG015_07125	COG0019	diaminopimelate decarboxylase activity
CG015_07160	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CG015_07165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CG015_07170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CG015_07180	COG0840	transmembrane signaling receptor activity
CG015_07195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG015_07195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG015_07195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG015_07200	COG2207	Transcriptional regulator
CG015_07210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG015_07220	COG1342	Belongs to the UPF0251 family
CG015_07240	COG1129	ABC transporter
CG015_07250	COG0583	DNA-binding transcription factor activity
CG015_07255	COG1902	pentaerythritol trinitrate reductase activity
CG015_07260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CG015_07265	COG5002	protein histidine kinase activity
CG015_07270	COG0745	RESPONSE REGULATOR receiver
CG015_07300	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CG015_07305	COG0372	Belongs to the citrate synthase family
CG015_07310	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CG015_07315	COG2828	Protein conserved in bacteria
CG015_07335	COG0561	phosphatase activity
CG015_07340	COG0602	queuosine metabolic process
CG015_07505	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CG015_07510	COG1254	Belongs to the acylphosphatase family
CG015_07515	COG2920	part of a sulfur-relay system
CG015_07520	COG0670	Belongs to the BI1 family
CG015_07525	COG1126	abc transporter atp-binding protein
CG015_07530	COG0765	amino acid transport
CG015_07535	COG4597	amino acid ABC transporter
CG015_07540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG015_07545	COG1648	precorrin-2 dehydrogenase activity
CG015_07545	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG015_07555	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CG015_07560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CG015_07560	COG0574	Belongs to the PEP-utilizing enzyme family
CG015_07575	COG2996	Protein conserved in bacteria
CG015_07585	COG3008	intermembrane lipid transfer
CG015_07590	COG2995	paraquat-inducible protein a
CG015_07595	COG1132	(ABC) transporter
CG015_07600	COG1956	GAF domain-containing protein
CG015_07620	COG0308	aminopeptidase N
CG015_07630	COG2902	Dehydrogenase
CG015_07635	COG0167	dihydroorotate dehydrogenase activity
CG015_07645	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CG015_07645	COG0116	Belongs to the methyltransferase superfamily
CG015_07670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CG015_07675	COG1067	ATP-dependent peptidase activity
CG015_07680	COG3120	sequence-specific DNA binding
CG015_07700	COG3278	Belongs to the heme-copper respiratory oxidase family
CG015_07715	COG2010	Cytochrome c
CG015_07725	COG2217	Heavy metal translocating P-type atpase
CG015_07740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CG015_07745	COG0589	response to stress
CG015_07770	COG3842	ATPase activity
CG015_07775	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG015_07780	COG1177	transmembrane transport
CG015_07785	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CG015_07790	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CG015_07795	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CG015_07800	COG0004	ammonium transporteR
CG015_07805	COG0488	(ABC) transporter
CG015_07810	COG2197	response regulator
CG015_07820	COG2271	Major facilitator Superfamily
CG015_07825	COG1840	ABC-type Fe3 transport system, periplasmic component
CG015_07835	COG3842	ATPase activity
CG015_07840	COG0746	molybdenum cofactor guanylyltransferase activity
CG015_07845	COG1763	Mo-molybdopterin cofactor biosynthetic process
CG015_07870	COG0840	transmembrane signaling receptor activity
CG015_07875	COG0791	NLP P60 protein
CG015_07900	COG1793	dna ligase
CG015_07905	COG4667	esterase of the alpha-beta hydrolase superfamily
CG015_07920	COG0848	biopolymer transport protein
CG015_07925	COG0811	peptide transport
CG015_07930	COG0811	peptide transport
CG015_07960	COG0625	glutathione transferase activity
CG015_07970	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CG015_07980	COG2195	Cleaves the N-terminal amino acid of tripeptides
CG015_07995	COG1115	amino acid carrier protein
CG015_08000	COG1280	lysine exporter protein (LysE YggA)
CG015_08005	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CG015_08010	COG0477	Major facilitator Superfamily
CG015_08015	COG0583	DNA-binding transcription factor activity
CG015_08025	COG1643	Atp-dependent helicase
CG015_08045	COG3706	GGDEF domain
CG015_08065	COG0443	Heat shock 70 kDa protein
CG015_08095	COG1609	Transcriptional regulator
CG015_08100	COG2723	6-phospho-beta-galactosidase activity
CG015_08105	COG0513	Belongs to the DEAD box helicase family
CG015_08110	COG0243	molybdopterin cofactor binding
CG015_08115	COG3005	denitrification pathway
CG015_08120	COG1278	Cold shock
CG015_08135	COG4191	Histidine kinase
CG015_08135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG015_08140	COG0471	metal ion transport
CG015_08150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CG015_08160	COG3706	GGDEF domain
CG015_08170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG015_08175	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CG015_08180	COG3768	UPF0283 membrane protein
CG015_08185	COG3106	COG3106 Predicted ATPase
CG015_08210	COG0814	amino acid
CG015_08215	COG1760	l-serine dehydratase
CG015_08225	COG2356	endonuclease I
CG015_08230	COG0720	synthase
CG015_08235	COG0840	transmembrane signaling receptor activity
CG015_08240	COG0017	Asparaginyl-tRNA synthetase
CG015_08250	COG2201	protein-glutamate methylesterase activity
CG015_08255	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CG015_08260	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CG015_08265	COG0835	chemotaxis
CG015_08275	COG2198	Histidine kinase
CG015_08275	COG0643	Histidine kinase
CG015_08285	COG0745	RESPONSE REGULATOR receiver
CG015_08295	COG2770	Histidine kinase
CG015_08295	COG3437	response regulator, receiver
CG015_08300	COG1448	Aminotransferase
CG015_08305	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CG015_08315	COG0840	transmembrane signaling receptor activity
CG015_08320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CG015_08325	COG1846	Transcriptional regulator
CG015_08340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG015_08345	COG3108	Peptidase M15
CG015_08350	COG2989	Protein conserved in bacteria
CG015_08380	COG1940	carbohydrate kinase activity
CG015_08385	COG4771	TonB-dependent receptor
CG015_08390	COG0748	coenzyme F420 binding
CG015_08395	COG3721	Heme iron utilization protein
CG015_08400	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CG015_08405	COG0811	peptide transport
CG015_08410	COG0848	biopolymer transport protein
CG015_08420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG015_08425	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CG015_08445	COG1621	beta-fructofuranosidase activity
CG015_08455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG015_08455	COG1263	PTS System
CG015_08460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG015_08465	COG2200	EAL domain
CG015_08470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CG015_08475	COG0840	transmembrane signaling receptor activity
CG015_08480	COG1294	oxidase, subunit
CG015_08485	COG1271	oxidase subunit
CG015_08510	COG3220	belongs to the UPF0276 family
CG015_08530	COG1294	oxidase, subunit
CG015_08540	COG0251	oxidation-reduction process
CG015_08560	COG0745	RESPONSE REGULATOR receiver
CG015_08560	COG3706	GGDEF domain
CG015_08575	COG0835	chemotaxis
CG015_08575	COG0784	Response regulator, receiver
CG015_08585	COG4565	transcriptional regulatory protein
CG015_08590	COG3290	protein histidine kinase activity
CG015_08605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG015_08630	COG3063	Type IV pilus biogenesis stability protein PilW
CG015_08645	COG1451	nucleotide metabolic process
CG015_08655	COG0583	DNA-binding transcription factor activity
CG015_08680	COG4139	cobalamin transport
CG015_08685	COG2988	succinylglutamate desuccinylase activity
CG015_08700	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CG015_08720	COG2994	toxin metabolic process
CG015_08750	COG0702	epimerase
CG015_08760	COG2925	Exonuclease
CG015_08770	COG1346	cytolysis
CG015_08775	COG0295	cytidine deaminase activity
CG015_08780	COG5001	Diguanylate cyclase
CG015_08785	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CG015_08795	COG0500	methyltransferase
CG015_08810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG015_08810	COG0072	phenylalanine-tRNA ligase activity
CG015_08855	COG0322	excinuclease ABC activity
CG015_08860	COG2197	response regulator
CG015_08865	COG0417	DNA replication proofreading
CG015_08875	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CG015_08880	COG3099	Belongs to the UPF0263 family
CG015_08895	COG1228	amidohydrolase
CG015_08900	COG0010	Belongs to the arginase family
CG015_08910	COG2986	histidine ammonia-lyase
CG015_08925	COG0247	lactate metabolic process
CG015_08925	COG0277	FAD linked oxidase domain protein
CG015_08955	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CG015_08960	COG1960	acyl-CoA dehydrogenase activity
CG015_08985	COG3300	MHYT domain
CG015_08985	COG5001	Diguanylate cyclase
CG015_09005	COG5002	protein histidine kinase activity
CG015_09005	COG0784	Response regulator, receiver
CG015_09020	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CG015_09025	COG2885	chlorophyll binding
CG015_09045	COG0811	peptide transport
CG015_09050	COG0824	Thioesterase
CG015_09055	COG3790	cyd operon protein YbgE
CG015_09060	COG4890	Cyd operon protein YbgT
CG015_09065	COG1294	oxidase, subunit
CG015_09070	COG1271	oxidase subunit
CG015_09075	COG2255	four-way junction helicase activity
CG015_09080	COG0632	four-way junction helicase activity
CG015_09085	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CG015_09090	COG0215	cysteine-tRNA ligase activity
CG015_09095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CG015_09105	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CG015_09110	COG3012	SEC-C Motif Domain Protein
CG015_09120	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CG015_09125	COG1199	ATP-dependent helicase activity
CG015_09135	COG3923	Primosomal replication protein n
CG015_09145	COG0840	transmembrane signaling receptor activity
CG015_09150	COG0708	Exodeoxyribonuclease III
CG015_09155	COG4160	amino acid transport
CG015_09160	COG4215	(ABC) transporter
CG015_09185	COG1882	Formate acetyltransferase
CG015_09200	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CG015_09215	COG2766	serine protein kinase
CG015_09220	COG2718	Belongs to the UPF0229 family
CG015_09225	COG2719	SpoVR family
CG015_09230	COG3038	cytochrome b561
CG015_09235	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CG015_09250	COG1132	(ABC) transporter
CG015_09255	COG2333	competence protein COMEC
CG015_09255	COG0658	competence protein
CG015_09265	COG4591	ABC-type transport system involved in lipoprotein release permease component
CG015_09270	COG1136	(ABC) transporter
CG015_09275	COG4591	ABC-type transport system involved in lipoprotein release permease component
CG015_09285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CG015_09300	COG1252	NADH dehydrogenase
CG015_09330	COG0537	adenosine 5'-monophosphoramidase activity
CG015_09345	COG2186	Transcriptional regulator
CG015_09350	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CG015_09360	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CG015_09365	COG2226	methyltransferase
CG015_09370	COG0156	8-amino-7-oxononanoate synthase activity
CG015_09380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG015_09390	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CG015_09395	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CG015_09400	COG0653	protein targeting
CG015_09405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CG015_09415	COG4120	Belongs to the binding-protein-dependent transport system permease family
CG015_09425	COG3092	negative regulation of chromosome organization
CG015_09430	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CG015_09435	COG0857	belongs to the CobB CobQ family
CG015_09435	COG0280	phosphate acetyltransferase
CG015_09440	COG0435	Glutathione S-transferase
CG015_09450	COG0444	Belongs to the ABC transporter superfamily
CG015_09455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG015_09460	COG0601	transmembrane transport
CG015_09475	COG0784	Response regulator, receiver
CG015_09475	COG5002	protein histidine kinase activity
CG015_09500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CG015_09505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CG015_09525	COG1215	transferase activity, transferring glycosyl groups
CG015_09555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CG015_09565	COG1028	Short-chain dehydrogenase reductase Sdr
CG015_09585	COG1538	Outer membrane efflux protein
CG015_09590	COG1566	PFAM secretion protein HlyD family protein
CG015_09615	COG0800	Aldolase
CG015_09620	COG2610	gluconate transmembrane transporter activity
CG015_09625	COG3265	gluconokinase activity
CG015_09630	COG0129	dihydroxy-acid dehydratase activity
CG015_09635	COG1609	Transcriptional regulator
CG015_09650	COG5002	protein histidine kinase activity
CG015_09650	COG3850	Histidine kinase
CG015_09660	COG2985	domain, Protein
CG015_09675	COG2194	sulfuric ester hydrolase activity
CG015_09680	COG0642	Histidine kinase
CG015_09685	COG0745	RESPONSE REGULATOR receiver
CG015_09705	COG1022	Amp-dependent synthetase and ligase
CG015_09730	COG3706	GGDEF domain
CG015_09750	COG1946	Acyl-CoA thioesterase
CG015_09755	COG1522	sequence-specific DNA binding
CG015_09790	COG0318	PFAM AMP-dependent synthetase and ligase
CG015_09795	COG1441	menaquinone biosynthetic process
CG015_09800	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CG015_09810	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CG015_09815	COG1169	isochorismate synthase
CG015_09825	COG0436	Aminotransferase
CG015_09830	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CG015_09835	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CG015_09850	COG0616	signal peptide processing
CG015_09855	COG1028	Short-chain dehydrogenase reductase Sdr
CG015_09860	COG0835	chemotaxis
CG015_09860	COG0784	Response regulator, receiver
CG015_09865	COG1940	carbohydrate kinase activity
CG015_09875	COG4667	esterase of the alpha-beta hydrolase superfamily
CG015_09885	COG0733	neurotransmitter:sodium symporter activity
CG015_09895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG015_09895	COG1263	PTS System
CG015_09900	COG0084	hydrolase, TatD family'
CG015_09905	COG0470	DNA polymerase III
CG015_09910	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CG015_09915	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CG015_09920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG015_09945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG015_09955	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CG015_09960	COG1399	metal-binding, possibly nucleic acid-binding protein
CG015_09965	COG0424	maF-like protein
CG015_09970	COG0564	pseudouridine synthase activity
CG015_09975	COG1530	ribonuclease E activity
CG015_09985	COG1012	belongs to the aldehyde dehydrogenase family
CG015_09985	COG1454	alcohol dehydrogenase
CG015_09990	COG2095	MarC family integral membrane protein
CG015_09995	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CG015_10000	COG1757	Na H antiporter
CG015_10015	COG3082	Protein of unknown function (DUF1414)
CG015_10020	COG3083	sulfuric ester hydrolase activity
CG015_10030	COG0243	molybdopterin cofactor binding
CG015_10035	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CG015_10050	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CG015_10055	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CG015_10075	COG2853	Lipoprotein
CG015_10090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG015_10095	COG1138	Cytochrome C-type biogenesis protein
CG015_10100	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CG015_10110	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG015_10115	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG015_10120	COG4133	protoheme IX ABC transporter activity
CG015_10130	COG0835	chemotaxis
CG015_10140	COG1192	Involved in chromosome partitioning
CG015_10145	COG2201	protein-glutamate methylesterase activity
CG015_10150	COG0643	Histidine kinase
CG015_10150	COG2198	Histidine kinase
CG015_10155	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CG015_10170	COG0455	bacterial-type flagellum organization
CG015_10180	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CG015_10185	COG2062	phosphohistidine phosphatase, SixA
CG015_10190	COG1025	Belongs to the peptidase M16 family
CG015_10195	COG3102	Protein conserved in bacteria
CG015_10220	COG1918	ferrous iron import across plasma membrane
CG015_10225	COG4977	sequence-specific DNA binding
CG015_10230	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CG015_10235	COG1121	(ABC) transporter
CG015_10240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CG015_10255	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG015_10260	COG0567	Dehydrogenase, E1 component
CG015_10275	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CG015_10280	COG2009	succinate dehydrogenase
CG015_10290	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CG015_10300	COG0033	Phosphoglucomutase
CG015_10305	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CG015_10310	COG0596	Alpha beta hydrolase
CG015_10320	COG0716	FMN binding
CG015_10325	COG1346	cytolysis
CG015_10335	COG0583	DNA-binding transcription factor activity
CG015_10345	COG0735	belongs to the Fur family
CG015_10350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CG015_10355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CG015_10360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CG015_10365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG015_10365	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CG015_10370	COG0431	NADPH-dependent FMN reductase
CG015_10380	COG3101	peptidyl-lysine hydroxylation
CG015_10385	COG2860	membrane
CG015_10390	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CG015_10395	COG2890	protein-(glutamine-N5) methyltransferase activity
CG015_10400	COG2840	Smr protein MutS2
CG015_10410	COG1684	flagellar biosynthetic protein fliR
CG015_10415	COG1987	bacterial-type flagellum assembly
CG015_10465	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG015_10475	COG1677	Flagellar hook-basal body complex protein FliE
CG015_10480	COG2204	response regulator
CG015_10485	COG4191	Histidine kinase
CG015_10490	COG2204	response regulator
CG015_10495	COG1516	flagellar protein fliS
CG015_10505	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CG015_10530	COG2837	iron assimilation
CG015_10555	COG1393	Belongs to the ArsC family
CG015_10560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG015_10580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG015_10590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CG015_10610	COG4783	chaperone-mediated protein folding
CG015_10615	COG1393	Belongs to the ArsC family
CG015_10635	COG2233	PERMEase
CG015_10640	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CG015_10650	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CG015_10655	COG2912	Transglutaminase-like superfamily
CG015_10660	COG3094	Invasion gene expression up-regulator, SirB
CG015_10665	COG2890	protein-(glutamine-N5) methyltransferase activity
CG015_10670	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CG015_10675	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CG015_10680	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CG015_10695	COG0193	aminoacyl-tRNA hydrolase activity
CG015_10800	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG015_10810	COG3951	Flagellar rod assembly protein muramidase FlgJ
CG015_10810	COG1705	Flagellar rod assembly protein muramidase FlgJ
CG015_10815	COG1706	bacterial-type flagellum-dependent cell motility
CG015_10820	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CG015_10825	COG4786	Flagellar basal body rod
CG015_10830	COG4787	bacterial-type flagellum-dependent cell motility
CG015_10835	COG1749	Flagellar hook protein flgE
CG015_10840	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CG015_10845	COG1558	bacterial-type flagellum-dependent cell motility
CG015_10850	COG1815	bacterial-type flagellum-dependent cell motility
CG015_10860	COG0835	chemotaxis
CG015_10860	COG0784	Response regulator, receiver
CG015_10870	COG2747	anti-sigma28 factor FlgM
CG015_10915	COG2217	Heavy metal translocating P-type atpase
CG015_10915	COG2608	mercury ion transmembrane transporter activity
CG015_10940	COG1187	pseudouridine synthase activity
CG015_10945	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CG015_10950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CG015_10955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CG015_10960	COG0121	glutamine amidotransferase
CG015_10965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CG015_10980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CG015_10990	COG2226	methyltransferase
CG015_10995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG015_11000	COG0741	lytic transglycosylase activity
CG015_11000	COG1388	LysM domain
CG015_11015	COG0347	Belongs to the P(II) protein family
CG015_11025	COG0037	tRNA processing
CG015_11030	COG0825	malonyl-CoA metabolic process
CG015_11035	COG0587	DNA-directed DNA polymerase activity
CG015_11045	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CG015_11055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CG015_11060	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CG015_11065	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CG015_11075	COG0750	zinc metalloprotease
CG015_11080	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CG015_11085	COG0575	Belongs to the CDS family
CG015_11090	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CG015_11095	COG0233	cytoplasmic translational termination
CG015_11105	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CG015_11110	COG0052	Belongs to the universal ribosomal protein uS2 family
CG015_11115	COG0024	Methionine aminopeptidase
CG015_11130	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CG015_11135	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CG015_11160	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG015_11160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG015_11170	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CG015_11175	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CG015_11195	COG2252	PERMEase
CG015_11200	COG2195	Cleaves the N-terminal amino acid of tripeptides
CG015_11210	COG0189	ligase activity
CG015_11220	COG0733	neurotransmitter:sodium symporter activity
CG015_11225	COG4251	negative regulation of phosphorylation
CG015_11225	COG3706	GGDEF domain
CG015_11225	COG5001	Diguanylate cyclase
CG015_11225	COG2203	Gaf domain
CG015_11235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CG015_11245	COG1477	protein flavinylation
CG015_11280	COG0271	Belongs to the BolA IbaG family
CG015_11300	COG2211	Major facilitator Superfamily
CG015_11310	COG1595	DNA-templated transcription, initiation
CG015_11325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CG015_11335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CG015_11340	COG2166	iron-sulfur cluster assembly
CG015_11345	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CG015_11350	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CG015_11360	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CG015_11360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CG015_11370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CG015_11375	COG1074	ATP-dependent DNA helicase activity
CG015_11380	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CG015_11395	COG3141	response to X-ray
CG015_11400	COG2171	N-acyltransferase activity
CG015_11430	COG1609	Transcriptional regulator
CG015_11440	COG1085	galactose-1-phosphate uridylyltransferase
CG015_11450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CG015_11455	COG0534	Mate efflux family protein
CG015_11465	COG0784	Response regulator, receiver
CG015_11465	COG3437	response regulator, receiver
CG015_11470	COG1022	Amp-dependent synthetase and ligase
CG015_11475	COG4628	conserved protein (DUF2132)
CG015_11480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CG015_11485	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CG015_11495	COG0560	Phosphoserine phosphatase
CG015_11505	COG0813	purine-nucleoside phosphorylase activity
CG015_11510	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CG015_11520	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CG015_11525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG015_11530	COG0084	hydrolase, TatD family'
CG015_11540	COG1115	amino acid carrier protein
CG015_11555	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CG015_11560	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CG015_11565	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CG015_11570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CG015_11575	COG0083	homoserine kinase activity
CG015_11590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CG015_11595	COG0745	RESPONSE REGULATOR receiver
CG015_11605	COG2198	Histidine kinase
CG015_11605	COG0784	Response regulator, receiver
CG015_11605	COG5002	protein histidine kinase activity
CG015_11610	COG1242	4 iron, 4 sulfur cluster binding
CG015_11615	COG0067	glutamate synthase
CG015_11615	COG0069	glutamate synthase activity
CG015_11615	COG0070	glutamate synthase
CG015_11625	COG0069	glutamate synthase activity
CG015_11625	COG0067	glutamate synthase
CG015_11625	COG0070	glutamate synthase
CG015_11630	COG0493	'glutamate synthase
CG015_11655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG015_11660	COG2860	membrane
CG015_11665	COG0583	DNA-binding transcription factor activity
CG015_11670	COG0730	response to heat
CG015_11680	COG0505	Belongs to the CarA family
CG015_11690	COG0494	nUDIX hydrolase
CG015_11695	COG0653	protein targeting
CG015_11705	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CG015_11710	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CG015_11715	COG0849	cell division
CG015_11720	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CG015_11725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CG015_11730	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG015_11735	COG0772	Belongs to the SEDS family
CG015_11740	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CG015_11745	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CG015_11750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CG015_11755	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CG015_11760	COG0768	penicillin binding
CG015_11765	COG3116	cell division
CG015_11780	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CG015_11785	COG3107	peptidoglycan biosynthetic process
CG015_11795	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CG015_11805	COG2969	positive regulation of protein catabolic process
CG015_11810	COG0625	glutathione transferase activity
CG015_11815	COG2857	Cytochrome c1
CG015_11820	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CG015_11825	COG0723	plastoquinol--plastocyanin reductase activity
CG015_11845	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CG015_11850	COG3105	Protein conserved in bacteria
CG015_11855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG015_11860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG015_11865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CG015_11870	COG0187	DNA topoisomerase II activity
CG015_11875	COG3150	esterase
CG015_11885	COG3151	Protein conserved in bacteria
CG015_11890	COG0494	nUDIX hydrolase
CG015_11895	COG1538	Outer membrane efflux protein
CG015_11905	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CG015_11920	COG3025	triphosphatase activity
CG015_11925	COG1392	Phosphate transport regulator
CG015_11930	COG0306	phosphate transporter
CG015_11935	COG4991	sh3 domain protein
CG015_11945	COG3409	Peptidoglycan-binding domain 1 protein
CG015_11945	COG3267	Type II secretory pathway component ExeA
CG015_11950	COG0617	tRNA 3'-terminal CCA addition
CG015_11960	COG0504	CTP synthase activity
CG015_11965	COG3956	TIGRFAM MazG family protein
CG015_11970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CG015_11975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CG015_11980	COG3437	response regulator, receiver
CG015_11980	COG2205	protein histidine kinase activity
CG015_11980	COG4999	Histidine kinase
CG015_11980	COG3850	Histidine kinase
CG015_12010	COG0681	Belongs to the peptidase S26 family
CG015_12015	COG0481	GTPase activity
CG015_12020	COG3086	response to oxidative stress
CG015_12035	COG1595	DNA-templated transcription, initiation
CG015_12040	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CG015_12050	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CG015_12055	COG0354	folic acid binding
CG015_12070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CG015_12075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CG015_12085	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CG015_12095	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CG015_12105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CG015_12115	COG0028	Belongs to the TPP enzyme family
CG015_12120	COG1022	Amp-dependent synthetase and ligase
CG015_12125	COG0583	DNA-binding transcription factor activity
CG015_12140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG015_12145	COG0473	3-isopropylmalate dehydrogenase activity
CG015_12155	COG0066	3-isopropylmalate dehydratase activity
CG015_12220	COG0795	lipopolysaccharide-transporting ATPase activity
CG015_12225	COG0795	lipopolysaccharide-transporting ATPase activity
CG015_12230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CG015_12235	COG2927	DNA polymerase III (CHI subunit)
CG015_12240	COG0525	valine-tRNA ligase activity
CG015_12245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG015_12250	COG0564	pseudouridine synthase activity
CG015_12260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CG015_12270	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CG015_12285	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CG015_12290	COG0251	oxidation-reduction process
CG015_12305	COG0204	Acyl-transferase
CG015_12310	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CG015_12315	COG5007	Belongs to the BolA IbaG family
CG015_12325	COG2854	intermembrane phospholipid transfer
CG015_12330	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CG015_12335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CG015_12340	COG1127	ABC transporter
CG015_12350	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CG015_12350	COG0517	IMP dehydrogenase activity
CG015_12355	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CG015_12365	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CG015_12370	COG1137	ATPase activity
CG015_12380	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CG015_12385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG015_12395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG015_12400	COG2239	Acts as a magnesium transporter
CG015_12405	COG0312	modulator of DNA gyrase
CG015_12410	COG3028	Belongs to the UPF0307 family
CG015_12415	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CG015_12420	COG1178	ABC-type Fe3 transport system permease component
CG015_12425	COG4143	(ABC) transporter
CG015_12430	COG0163	prenyltransferase activity
CG015_12435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CG015_12440	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CG015_12445	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CG015_12455	COG2105	PFAM AIG2 family protein
CG015_12460	COG2911	Protein conserved in bacteria
CG015_12465	COG0729	surface antigen
CG015_12470	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG015_12475	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CG015_12510	COG0529	Catalyzes the synthesis of activated sulfate
CG015_12515	COG2895	sulfate adenylyltransferase (ATP) activity
CG015_12520	COG0175	sulfate reduction
CG015_12525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG015_12525	COG1648	precorrin-2 dehydrogenase activity
CG015_12530	COG0737	Belongs to the 5'-nucleotidase family
CG015_12570	COG0513	Belongs to the DEAD box helicase family
CG015_12575	COG2153	protein acetylation
CG015_12580	COG3266	domain, Protein
CG015_12580	COG3061	Opacity-associated protein A
CG015_12585	COG0545	Peptidyl-prolyl cis-trans isomerase
CG015_12590	COG0203	ribosomal protein L17
CG015_12600	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CG015_12605	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CG015_12610	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CG015_12620	COG0201	protein transport
CG015_12645	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CG015_12650	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CG015_12670	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CG015_12675	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CG015_12700	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CG015_12725	COG0051	transcription antitermination factor activity, RNA binding
CG015_12730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG015_12735	COG0557	exoribonuclease II activity
CG015_12740	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CG015_12750	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CG015_12760	COG1047	Peptidyl-prolyl cis-trans
CG015_12765	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CG015_12775	COG2249	NAD(P)H dehydrogenase (quinone) activity
CG015_12780	COG0488	(ABC) transporter
CG015_12790	COG0429	hydrolase of the alpha beta-hydrolase fold
CG015_12800	COG3954	Phosphoribulokinase
CG015_12805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CG015_12825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CG015_12840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CG015_12850	COG0583	DNA-binding transcription factor activity
CG015_12865	COG0180	Tryptophanyl-tRNA synthetase
CG015_12870	COG0546	phosphoglycolate phosphatase activity
CG015_12875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CG015_12880	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CG015_12895	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CG015_12925	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CG015_12935	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CG015_12935	COG0678	peroxiredoxin activity
CG015_12940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CG015_12950	COG0165	Argininosuccinate lyase
CG015_12950	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CG015_12960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CG015_12965	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CG015_12985	COG1045	serine acetyltransferase
CG015_12990	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CG015_13000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CG015_13005	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CG015_13010	COG1053	succinate dehydrogenase
CG015_13015	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CG015_13020	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CG015_13030	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CG015_13035	COG1509	lysine 2,3-aminomutase activity
CG015_13050	COG0459	protein refolding
CG015_13080	COG0149	triose-phosphate isomerase activity
CG015_13085	COG0534	Mate efflux family protein
CG015_13090	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CG015_13095	COG1575	Belongs to the MenA family. Type 1 subfamily
CG015_13115	COG1609	Transcriptional regulator
CG015_13120	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CG015_13130	COG0281	malic enzyme
CG015_13140	COG0626	cystathionine gamma-synthase activity
CG015_13145	COG0460	homoserine dehydrogenase
CG015_13145	COG0527	aspartate kinase activity
CG015_13150	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CG015_13160	COG1494	fructose-1,6-bisphosphatase
CG015_13165	COG0205	6-phosphofructokinase activity
CG015_13170	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CG015_13180	COG0745	RESPONSE REGULATOR receiver
CG015_13185	COG2205	protein histidine kinase activity
CG015_13190	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CG015_13195	COG1278	Cold shock
CG015_13200	COG3030	protein affecting phage T7 exclusion by the F plasmid
CG015_13205	COG1027	Aspartate ammonia-lyase
CG015_13210	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CG015_13215	COG1288	antiporter activity
CG015_13225	COG0549	Belongs to the carbamate kinase family
CG015_13230	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CG015_13240	COG0540	Belongs to the ATCase OTCase family
CG015_13245	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CG015_13250	COG1438	arginine binding
CG015_13255	COG4232	protein-disulfide reductase activity
CG015_13265	COG3263	regulation of cellular component size
CG015_13280	COG2205	protein histidine kinase activity
CG015_13280	COG2198	Histidine kinase
CG015_13280	COG0784	Response regulator, receiver
CG015_13285	COG2814	Major facilitator Superfamily
CG015_13300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG015_13305	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CG015_13310	COG0511	ligase activity, forming carbon-carbon bonds
CG015_13315	COG0439	Biotin carboxylase
CG015_13320	COG2264	protein methyltransferase activity
CG015_13325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CG015_13330	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CG015_13335	COG0840	transmembrane signaling receptor activity
CG015_13340	COG0789	Transcriptional regulator
CG015_13350	COG0151	Belongs to the GarS family
CG015_13360	COG0776	regulation of translation
CG015_13365	COG1253	flavin adenine dinucleotide binding
CG015_13375	COG3068	Protein conserved in bacteria
CG015_13380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CG015_13385	COG0668	transmembrane transport
CG015_13390	COG0840	transmembrane signaling receptor activity
CG015_13395	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CG015_13400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CG015_13405	COG0438	transferase activity, transferring glycosyl groups
CG015_13415	COG0438	transferase activity, transferring glycosyl groups
CG015_13420	COG1216	Glycosyl transferase, family 2
CG015_13430	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CG015_13485	COG0523	cobalamin synthesis protein
CG015_13500	COG0156	8-amino-7-oxononanoate synthase activity
CG015_13510	COG0419	ATPase involved in DNA repair
CG015_13515	COG0420	3'-5' exonuclease activity
CG015_13520	COG1609	Transcriptional regulator
CG015_13525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG015_13525	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG015_13530	COG1105	Belongs to the carbohydrate kinase PfkB family
CG015_13535	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CG015_13535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG015_13535	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG015_13550	COG0612	Peptidase, M16
CG015_13565	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CG015_13575	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CG015_13600	COG0697	spore germination
CG015_13610	COG1335	isochorismatase
CG015_13625	COG0861	Integral membrane protein TerC family
CG015_13645	COG2814	Major facilitator Superfamily
CG015_13660	COG4604	ABC transporter, ATP-binding protein
CG015_13665	COG4605	iron ion homeostasis
CG015_13670	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG015_13675	COG4607	ABC-type enterochelin transport system periplasmic component
CG015_13700	COG3291	Pkd domain containing protein
CG015_13700	COG4412	M6 family metalloprotease domain protein
CG015_13705	COG5380	lipid catabolic process
CG015_13710	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CG015_13720	COG3240	lipase activity
CG015_13735	COG0443	Heat shock 70 kDa protein
CG015_13745	COG2814	Major facilitator Superfamily
CG015_13755	COG4191	Histidine kinase
CG015_13755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG015_13765	COG0784	Response regulator, receiver
CG015_13765	COG3437	response regulator, receiver
CG015_13770	COG2207	Transcriptional regulator
CG015_13775	COG0534	Mate efflux family protein
CG015_13780	COG0840	transmembrane signaling receptor activity
CG015_13785	COG3186	Phenylalanine-4-hydroxylase
CG015_13790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG015_13805	COG0583	DNA-binding transcription factor activity
CG015_13820	COG0110	maltose O-acetyltransferase activity
CG015_13825	COG1765	OsmC-like protein
CG015_13830	COG0673	inositol 2-dehydrogenase activity
CG015_13865	COG0784	Response regulator, receiver
CG015_13865	COG5002	protein histidine kinase activity
CG015_13865	COG2205	protein histidine kinase activity
CG015_13890	COG0531	amino acid
CG015_13905	COG3437	response regulator, receiver
CG015_13915	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CG015_13925	COG5001	Diguanylate cyclase
CG015_13925	COG3706	GGDEF domain
CG015_13925	COG4251	negative regulation of phosphorylation
CG015_13925	COG2203	Gaf domain
CG015_13930	COG3279	Response regulator of the LytR AlgR family
CG015_13950	COG4591	ABC-type transport system involved in lipoprotein release permease component
CG015_13955	COG0577	efflux transmembrane transporter activity
CG015_13955	COG1136	(ABC) transporter
CG015_13965	COG4989	oxidoreductase activity
CG015_13970	COG0366	Alpha amylase catalytic
CG015_13980	COG2267	carboxylic ester hydrolase activity
CG015_14010	COG0513	Belongs to the DEAD box helicase family
CG015_14020	COG1376	ErfK ybiS ycfS ynhG family protein
CG015_14020	COG1388	LysM domain
CG015_14025	COG0415	Belongs to the DNA photolyase family
CG015_14030	COG0789	Transcriptional regulator
CG015_14035	COG3272	Protein of unknown function (DUF1722)
CG015_14040	COG0813	purine-nucleoside phosphorylase activity
CG015_14055	COG3706	GGDEF domain
CG015_14065	COG1566	PFAM secretion protein HlyD family protein
CG015_14105	COG1999	signal sequence binding
CG015_14115	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CG015_14135	COG4580	involved in the transport of maltose and maltodextrins
CG015_14170	COG0561	phosphatase activity
CG015_14175	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CG015_14180	COG3623	hexulose-6-phosphate isomerase
CG015_14200	COG1132	(ABC) transporter
CG015_14205	COG4399	Belongs to the UPF0754 family
CG015_14210	COG0671	phosphoesterase, PA-phosphatase related
CG015_14240	COG0840	transmembrane signaling receptor activity
CG015_14250	COG1131	(ABC) transporter
CG015_14255	COG2188	Transcriptional regulator
CG015_14265	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CG015_14405	COG0564	pseudouridine synthase activity
CG015_14415	COG0745	RESPONSE REGULATOR receiver
CG015_14430	COG1309	transcriptional regulator
CG015_14435	COG2130	NADP-dependent
CG015_14445	COG1328	CTP reductase activity
CG015_14460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CG015_14465	COG0251	oxidation-reduction process
CG015_14470	COG0513	Belongs to the DEAD box helicase family
CG015_14490	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG015_14500	COG3842	ATPase activity
CG015_14515	COG1131	(ABC) transporter
CG015_14520	COG0842	Transport permease protein
CG015_14525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CG015_14530	COG3046	protein related to deoxyribodipyrimidine photolyase
CG015_14535	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CG015_14545	COG1846	Transcriptional regulator
CG015_14570	COG2259	Doxx family
CG015_14575	COG1301	dicarboxylic acid transport
CG015_14580	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CG015_14590	COG3722	fumarate hydratase activity
CG015_14595	COG0246	Mannitol dehydrogenase
CG015_14600	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG015_14600	COG2213	PTS system mannitol-specific
CG015_14605	COG0739	heme binding
CG015_14615	COG0363	glucosamine-6-phosphate deaminase activity
CG015_14635	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CG015_14640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CG015_14660	COG3304	Inner membrane component domain
CG015_14670	COG2910	NAD(P)H-binding
CG015_14675	COG0583	DNA-binding transcription factor activity
CG015_14705	COG0814	amino acid
CG015_14710	COG2084	Dehydrogenase
CG015_14755	COG1444	tRNA N-acetyltransferase activity
CG015_14770	COG2198	Histidine kinase
CG015_14770	COG0643	Histidine kinase
CG015_14775	COG0835	chemotaxis
CG015_14785	COG0840	transmembrane signaling receptor activity
CG015_14790	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CG015_14795	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CG015_14815	COG0745	RESPONSE REGULATOR receiver
CG015_14815	COG3706	GGDEF domain
CG015_14845	COG0259	pyridoxamine-phosphate oxidase activity
CG015_14855	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CG015_14890	COG0840	transmembrane signaling receptor activity
CG015_14910	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CG015_14935	COG2909	trisaccharide binding
CG015_14940	COG0058	SHG alpha-glucan phosphorylase activity
CG015_14945	COG1640	4-alpha-glucanotransferase
CG015_14950	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CG015_14960	COG3501	Rhs element vgr protein
CG015_14975	COG1869	D-ribose catabolic process
CG015_14980	COG1129	ABC transporter
CG015_14985	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG015_14990	COG1879	ABC-type sugar transport system periplasmic component
CG015_14995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG015_15015	COG0583	DNA-binding transcription factor activity
CG015_15025	COG0363	glucosamine-6-phosphate deaminase activity
CG015_15030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CG015_15040	COG1067	ATP-dependent peptidase activity
CG015_15070	COG4580	involved in the transport of maltose and maltodextrins
CG015_15075	COG1609	Transcriptional regulator
CG015_15090	COG0395	ABC-type sugar transport system, permease component
CG015_15095	COG3842	ATPase activity
CG015_15105	COG1609	Transcriptional regulator
CG015_15125	COG3568	Endonuclease Exonuclease Phosphatase
CG015_15135	COG3122	Protein conserved in bacteria
CG015_15140	COG1230	cation diffusion facilitator family transporter
CG015_15155	COG1881	PFAM PEBP family protein
CG015_15170	COG1304	FMN binding
CG015_15180	COG0583	DNA-binding transcription factor activity
CG015_15210	COG3527	Alpha-acetolactate decarboxylase
CG015_15220	COG0584	glycerophosphoryl diester phosphodiesterase
CG015_15225	COG2271	Major facilitator Superfamily
CG015_15230	COG3397	chitin binding
CG015_15240	COG3047	cAMP biosynthetic process
CG015_15250	COG0393	Putative heavy-metal-binding
CG015_15260	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CG015_15275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG015_15280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG015_15290	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CG015_15295	COG0573	inorganic phosphate transmembrane transporter activity
CG015_15300	COG0581	inorganic phosphate transmembrane transporter activity
CG015_15305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CG015_15335	COG0739	heme binding
CG015_15340	COG5001	Diguanylate cyclase
CG015_15345	COG0583	DNA-binding transcription factor activity
CG015_15350	COG2814	Major facilitator Superfamily
CG015_15370	COG0697	spore germination
CG015_15380	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG015_15400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG015_15405	COG0765	amino acid transport
CG015_15410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG015_15415	COG0765	amino acid transport
CG015_15425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CG015_15435	COG3123	guanosine phosphorylase activity
CG015_15445	COG1741	Belongs to the pirin family
CG015_15455	COG5001	Diguanylate cyclase
CG015_15490	COG3706	GGDEF domain
CG015_15495	COG2315	Protein conserved in bacteria
CG015_15500	COG0835	chemotaxis
CG015_15500	COG0784	Response regulator, receiver
CG015_15505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CG015_15515	COG3842	ATPase activity
CG015_15530	COG1175	transmembrane transport
CG015_15565	COG3706	GGDEF domain
CG015_15585	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CG015_15590	COG2354	Protein conserved in bacteria
CG015_15605	COG3217	Mosc domain protein beta barrel domain protein
CG015_15605	COG0633	Ferredoxin
CG015_15610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG015_15625	COG3604	Transcriptional regulator
CG015_15630	COG1017	nitric oxide dioxygenase activity
CG015_15630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CG015_15635	COG4681	YaeQ
CG015_15640	COG1278	Cold shock
CG015_15665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG015_15670	COG0516	GMP reductase activity
CG015_15705	COG0589	response to stress
CG015_15710	COG0659	secondary active sulfate transmembrane transporter activity
CG015_15715	COG0640	Transcriptional regulator
CG015_15720	COG0798	PFAM Bile acid sodium symporter
CG015_15725	COG0640	Transcriptional regulator
CG015_15730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CG015_15770	COG3851	Histidine kinase
CG015_15775	COG2197	response regulator
CG015_15790	COG0346	lactoylglutathione lyase activity
CG015_15800	COG0156	8-amino-7-oxononanoate synthase activity
CG015_15805	COG1063	alcohol dehydrogenase
CG015_15810	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CG015_15820	COG1368	sulfuric ester hydrolase activity
CG015_15825	COG3530	Putative quorum-sensing-regulated virulence factor
CG015_15830	COG1403	HNH endonuclease
CG015_15840	COG3706	GGDEF domain
CG015_15855	COG2304	oxidoreductase activity
CG015_15875	COG0714	Associated with various cellular activities
CG015_15895	COG0366	Alpha amylase catalytic
CG015_15935	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CG015_15945	COG0456	acetyltransferase
CG015_15950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CG015_15955	COG0662	Cupin 2, conserved barrel domain protein
CG015_15960	COG0527	aspartate kinase activity
CG015_15980	COG2113	Glycine betaine
CG015_16000	COG1166	arginine decarboxylase activity
CG015_16005	COG0010	Belongs to the arginase family
CG015_16030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG015_16045	COG0784	Response regulator, receiver
CG015_16045	COG3437	response regulator, receiver
CG015_16070	COG0484	heat shock protein binding
CG015_16085	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CG015_16095	COG4181	ATPase activity
CG015_16100	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CG015_16110	COG1984	allophanate hydrolase subunit 2
CG015_16125	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CG015_16135	COG0814	amino acid
CG015_16140	COG0513	Belongs to the DEAD box helicase family
CG015_16150	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CG015_16165	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CG015_16180	COG4175	Glycine betaine
CG015_16180	COG0517	IMP dehydrogenase activity
CG015_16185	COG4176	ABC-type proline glycine betaine transport system permease component
CG015_16220	COG2205	protein histidine kinase activity
CG015_16235	COG2146	nitrite reductase [NAD(P)H] activity
CG015_16250	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CG015_16270	COG3118	belongs to the thioredoxin family
CG015_16275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG015_16280	COG0247	lactate metabolic process
CG015_16285	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CG015_16290	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CG015_16295	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CG015_16300	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CG015_16325	COG2827	Endonuclease containing a URI domain
CG015_16340	COG5002	protein histidine kinase activity
CG015_16340	COG0784	Response regulator, receiver
CG015_16370	COG1289	transmembrane transporter activity
CG015_16375	COG0210	DNA helicase
CG015_16380	COG1803	Methylglyoxal synthase
CG015_16385	COG1879	ABC-type sugar transport system periplasmic component
CG015_16390	COG0784	Response regulator, receiver
CG015_16390	COG2198	Histidine kinase
CG015_16390	COG2205	protein histidine kinase activity
CG015_16395	COG0469	pyruvate kinase activity
CG015_16400	COG2271	Major facilitator Superfamily
CG015_16410	COG1840	ABC-type Fe3 transport system, periplasmic component
CG015_16425	COG1979	alcohol dehydrogenase
CG015_16430	COG2207	Transcriptional regulator
CG015_16445	COG5002	protein histidine kinase activity
CG015_16445	COG5001	Diguanylate cyclase
CG015_16445	COG3447	MASE1 domain protein
CG015_16455	COG3111	PFAM Bacterial OB fold (BOF) protein
CG015_16465	COG0725	ABC transporter, periplasmic molybdate-binding protein
CG015_16470	COG4149	molybdate abc transporter
CG015_16475	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CG015_16485	COG3706	GGDEF domain
CG015_16485	COG4251	negative regulation of phosphorylation
CG015_16485	COG2203	Gaf domain
CG015_16485	COG5001	Diguanylate cyclase
CG015_16500	COG0745	RESPONSE REGULATOR receiver
CG015_16510	COG3852	Histidine kinase
CG015_16515	COG4191	Histidine kinase
CG015_16520	COG3300	MHYT domain
CG015_16520	COG5001	Diguanylate cyclase
CG015_16540	COG0640	Transcriptional regulator
CG015_16565	COG3706	GGDEF domain
CG015_16570	COG1328	CTP reductase activity
CG015_16575	COG0602	queuosine metabolic process
CG015_16585	COG4067	protein conserved in archaea
CG015_16585	COG0189	ligase activity
CG015_16600	COG4166	transmembrane transport
CG015_16605	COG4174	ABC transporter (Permease)
CG015_16610	COG4239	(ABC) transporter, permease
CG015_16620	COG5001	Diguanylate cyclase
CG015_16620	COG3706	GGDEF domain
CG015_16620	COG2203	Gaf domain
CG015_16620	COG4251	negative regulation of phosphorylation
CG015_16630	COG3038	cytochrome b561
CG015_16635	COG2353	YceI-like domain
CG015_16645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CG015_16650	COG0545	Peptidyl-prolyl cis-trans isomerase
CG015_16665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CG015_16685	COG2897	thiosulfate sulfurtransferase activity
CG015_16690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG015_16695	COG0303	'Molybdopterin
CG015_16700	COG0302	gtp cyclohydrolase
CG015_16710	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CG015_16715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG015_16720	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CG015_16730	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CG015_16735	COG1011	Hydrolase
CG015_16740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CG015_16745	COG2188	Transcriptional regulator
CG015_16765	COG2116	formate transmembrane transporter activity
CG015_16770	COG0583	DNA-binding transcription factor activity
CG015_16780	COG3593	DNA synthesis involved in DNA repair
CG015_16785	COG0737	Belongs to the 5'-nucleotidase family
CG015_16790	COG0861	Integral membrane protein TerC family
CG015_16800	COG2824	Alkylphosphonate utilization operon protein PhnA
CG015_16810	COG2050	protein possibly involved in aromatic compounds catabolism
CG015_16825	COG0488	(ABC) transporter
CG015_16830	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CG015_16845	COG0625	glutathione transferase activity
CG015_16850	COG2501	S4 domain
CG015_16865	COG0840	transmembrane signaling receptor activity
CG015_16875	COG1278	Cold shock
CG015_16880	COG3706	GGDEF domain
CG015_16910	COG0745	RESPONSE REGULATOR receiver
CG015_16925	COG3140	Belongs to the UPF0181 family
CG015_16940	COG0583	DNA-binding transcription factor activity
CG015_16945	COG0045	succinate-CoA ligase (ADP-forming) activity
CG015_16945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG015_16945	COG1042	CoA-binding domain protein
CG015_16955	COG1181	Belongs to the D-alanine--D-alanine ligase family
CG015_16970	COG0023	Translation Initiation Factor
CG015_17030	COG3040	lipid binding
CG015_17065	COG0456	acetyltransferase
CG015_17165	COG1028	Short-chain dehydrogenase reductase Sdr
CG015_17225	COG0724	RNA recognition motif
CG015_17240	COG0384	phenazine biosynthesis protein PhzF
CG015_17275	COG0242	peptide deformylase activity
CG015_17285	COG0384	phenazine biosynthesis protein PhzF
CG015_17345	COG0242	peptide deformylase activity
CG015_17450	COG2161	toxin-antitoxin pair type II binding
CG015_17585	COG0653	protein targeting
CG015_17675	COG0242	peptide deformylase activity
CG015_17720	COG0653	protein targeting
CG015_17805	COG0110	maltose O-acetyltransferase activity
CG015_17880	COG0454	-acetyltransferase
CG015_18020	COG0724	RNA recognition motif
CG015_18025	COG4115	mRNA cleavage
CG015_18030	COG2161	toxin-antitoxin pair type II binding
CG015_18110	COG0653	protein targeting
CG015_18395	COG2161	toxin-antitoxin pair type II binding
CG015_18500	COG4974	Belongs to the 'phage' integrase family
CG015_18520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CG015_18525	COG0513	Belongs to the DEAD box helicase family
CG015_18530	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CG015_18540	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CG015_18565	COG3069	C4-dicarboxylate transmembrane transporter activity
CG015_18570	COG2197	response regulator
CG015_18575	COG3850	Histidine kinase
CG015_18580	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CG015_18590	COG0243	molybdopterin cofactor binding
CG015_18600	COG3005	denitrification pathway
CG015_18610	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG015_18615	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG015_18640	COG3730	PTS system glucitol sorbitol-specific
CG015_18645	COG1349	DNA-binding transcription factor activity
CG015_18650	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG015_18655	COG1028	Short-chain dehydrogenase reductase Sdr
CG015_18670	COG3730	PTS system glucitol sorbitol-specific
CG015_18700	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CG015_18725	COG1136	(ABC) transporter
CG015_18730	COG0523	cobalamin synthesis protein
CG015_18785	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CG015_18785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG015_18785	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity