locus-tag	class	description
KLK36_00035	COG0175	sulfate reduction
KLK36_00045	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KLK36_00065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KLK36_00070	COG0735	belongs to the Fur family
KLK36_00095	COG0166	Belongs to the GPI family
KLK36_00115	COG0359	binds to the 23S rRNA
KLK36_00125	COG2965	DNA replication, synthesis of RNA primer
KLK36_00130	COG0360	Binds together with S18 to 16S ribosomal RNA
KLK36_00135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KLK36_00140	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KLK36_00145	COG0049	tRNA binding
KLK36_00160	COG2923	Belongs to the DsrF TusC family
KLK36_00165	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KLK36_00170	COG2964	Protein conserved in bacteria
KLK36_00175	COG0545	Peptidyl-prolyl cis-trans isomerase
KLK36_00190	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
KLK36_00195	COG0330	HflC and HflK could
KLK36_00200	COG0330	HflC and HflK could
KLK36_00215	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KLK36_00220	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KLK36_00230	COG0802	atpase or kinase
KLK36_00285	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KLK36_00290	COG1162	GTPase activity
KLK36_00320	COG4942	peptidase
KLK36_00335	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KLK36_00345	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
KLK36_00350	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLK36_00360	COG0222	ribosome binding
KLK36_00365	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KLK36_00380	COG0250	Participates in transcription elongation, termination and antitermination
KLK36_00385	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KLK36_00390	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KLK36_00415	COG1072	(Pantothenic acid kinase))
KLK36_00420	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KLK36_00420	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KLK36_00425	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KLK36_00435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KLK36_00480	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KLK36_00495	COG3118	belongs to the thioredoxin family
KLK36_00515	COG0194	GDP metabolic process
KLK36_00520	COG1758	RNA polymerase activity
KLK36_00535	COG2233	PERMEase
KLK36_00570	COG0583	DNA-binding transcription factor activity
KLK36_00595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KLK36_00600	COG2183	response to ionizing radiation
KLK36_00610	COG0596	Alpha beta hydrolase
KLK36_00615	COG1040	competence protein
KLK36_00620	COG0316	Belongs to the HesB IscA family
KLK36_00620	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KLK36_00625	COG0494	nUDIX hydrolase
KLK36_00630	COG1218	3'(2'),5'-bisphosphate nucleotidase
KLK36_00640	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KLK36_00645	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KLK36_00650	COG3156	type II secretion system protein K
KLK36_00660	COG2165	general secretion pathway protein
KLK36_00665	COG2165	general secretion pathway protein
KLK36_00670	COG2165	general secretion pathway protein
KLK36_00675	COG1459	type II secretion system
KLK36_00680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KLK36_00690	COG3031	protein transport across the cell outer membrane
KLK36_00695	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KLK36_00700	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KLK36_00705	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KLK36_00715	COG0456	acetyltransferase
KLK36_00720	COG1490	D-aminoacyl-tRNA deacylase activity
KLK36_00725	COG1295	ribonuclease BN
KLK36_00730	COG1217	gtp-binding protein TYPA
KLK36_00735	COG0174	glutamine synthetase
KLK36_00745	COG3852	Histidine kinase
KLK36_00760	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KLK36_00830	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KLK36_00875	COG3550	peptidyl-serine autophosphorylation
KLK36_00915	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KLK36_00965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KLK36_00980	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KLK36_00985	COG2937	Belongs to the GPAT DAPAT family
KLK36_00995	COG3161	chorismate lyase activity
KLK36_01000	COG1580	Controls the rotational direction of flagella during chemotaxis
KLK36_01005	COG0705	Rhomboid family
KLK36_01015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KLK36_01020	COG2177	Part of the ABC transporter FtsEX involved in
KLK36_01025	COG2884	Cell division ATP-binding protein ftsE
KLK36_01035	COG0742	ribosomal rna small subunit methyltransferase
KLK36_01080	COG2433	Pfam Transposase IS66
KLK36_01095	COG2095	MarC family integral membrane protein
KLK36_01120	COG0783	Belongs to the Dps family
KLK36_01125	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KLK36_01130	COG1280	lysine exporter protein (LysE YggA)
KLK36_01135	COG2267	carboxylic ester hydrolase activity
KLK36_01140	COG0561	phosphatase activity
KLK36_01150	COG3148	PFAM DTW domain containing protein
KLK36_01155	COG1011	Hydrolase
KLK36_01160	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KLK36_01175	COG0019	diaminopimelate decarboxylase activity
KLK36_01200	COG1587	Uroporphyrinogen-III synthase
KLK36_01205	COG2959	enzyme of heme biosynthesis
KLK36_01210	COG3071	HemY protein
KLK36_01245	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KLK36_01255	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KLK36_01260	COG0408	coproporphyrinogen oxidase activity
KLK36_01265	COG0009	L-threonylcarbamoyladenylate synthase
KLK36_01270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KLK36_01275	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KLK36_01280	COG0551	DNA topoisomerase type I activity
KLK36_01285	COG2922	Belongs to the Smg family
KLK36_01290	COG0758	DNA mediated transformation
KLK36_01295	COG1652	LysM domain
KLK36_01305	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KLK36_01310	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KLK36_01310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KLK36_01315	COG0569	domain protein
KLK36_01320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KLK36_01330	COG1272	protein, Hemolysin III
KLK36_01335	COG3084	Protein conserved in bacteria
KLK36_01345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KLK36_01350	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KLK36_01370	COG2433	Pfam Transposase IS66
KLK36_01450	COG3978	acetolactate synthase activity
KLK36_01455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KLK36_01470	COG0604	alcohol dehydrogenase
KLK36_01485	COG0425	Belongs to the sulfur carrier protein TusA family
KLK36_01495	COG2119	membrane
KLK36_01500	COG0752	glycyl-tRNA synthetase alpha subunit
KLK36_01510	COG3977	Valine--pyruvate aminotransferase
KLK36_01515	COG0071	Belongs to the small heat shock protein (HSP20) family
KLK36_01525	COG0187	DNA topoisomerase II activity
KLK36_01530	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KLK36_01535	COG0592	DNA-directed DNA polymerase activity
KLK36_01555	COG1126	abc transporter atp-binding protein
KLK36_01575	COG0706	membrane insertase activity
KLK36_01585	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KLK36_01590	COG0445	tRNA wobble uridine modification
KLK36_01600	COG1192	Involved in chromosome partitioning
KLK36_01605	COG1475	DNA binding
KLK36_01610	COG3312	ion transport
KLK36_01625	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KLK36_01630	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLK36_01635	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KLK36_01640	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KLK36_01645	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KLK36_01650	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KLK36_01660	COG2814	Major facilitator Superfamily
KLK36_01665	COG0583	DNA-binding transcription factor activity
KLK36_01670	COG0183	Belongs to the thiolase family
KLK36_01680	COG1739	Uncharacterized protein family UPF0029
KLK36_01685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KLK36_01690	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
KLK36_01745	COG0352	thiamine-phosphate diphosphorylase activity
KLK36_01755	COG2104	thiamine diphosphate biosynthetic process
KLK36_01760	COG2022	thiamine diphosphate biosynthetic process
KLK36_01765	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KLK36_01770	COG0006	proline dipeptidase activity
KLK36_01770	COG0006	proline dipeptidase activity
KLK36_01795	COG1522	sequence-specific DNA binding
KLK36_01800	COG0742	ribosomal rna small subunit methyltransferase
KLK36_01815	COG0589	response to stress
KLK36_01820	COG1528	Iron-storage protein
KLK36_01835	COG2081	HI0933 family
KLK36_01845	COG1172	Belongs to the binding-protein-dependent transport system permease family
KLK36_01850	COG1129	ABC transporter
KLK36_01855	COG1879	ABC-type sugar transport system periplasmic component
KLK36_01860	COG1069	ribulokinase activity
KLK36_01870	COG2160	L-arabinose isomerase activity
KLK36_01890	COG1322	Protein conserved in bacteria
KLK36_01895	COG2226	methyltransferase
KLK36_01905	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KLK36_01910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KLK36_01915	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KLK36_01920	COG0805	protein transport
KLK36_01925	COG0084	hydrolase, TatD family'
KLK36_01940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KLK36_01940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KLK36_01980	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KLK36_01985	COG2960	long-chain fatty acid transporting porin activity
KLK36_01990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KLK36_01995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KLK36_02050	COG0601	transmembrane transport
KLK36_02110	COG2433	Pfam Transposase IS66
KLK36_02125	COG3081	Nucleoid-associated protein
KLK36_02145	COG2433	Pfam Transposase IS66
KLK36_02190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KLK36_02195	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KLK36_02200	COG0339	signal peptide processing
KLK36_02205	COG0210	DNA helicase
KLK36_02210	COG1280	lysine exporter protein (LysE YggA)
KLK36_02220	COG2962	Rard protein
KLK36_02225	COG0514	ATP-dependent DNA helicase (RecQ)
KLK36_02245	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KLK36_02250	COG1263	PTS System
KLK36_02250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KLK36_02255	COG1132	(ABC) transporter
KLK36_02260	COG4774	siderophore transport
KLK36_02265	COG1120	ATPase activity
KLK36_02315	COG2433	Pfam Transposase IS66
KLK36_02420	COG1561	YicC-like family, N-terminal region
KLK36_02425	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KLK36_02430	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KLK36_02435	COG1560	Kdo2-lipid A biosynthetic process
KLK36_02440	COG1560	Kdo2-lipid A biosynthetic process
KLK36_02445	COG1309	transcriptional regulator
KLK36_02450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KLK36_02455	COG2003	Belongs to the UPF0758 family
KLK36_02460	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KLK36_02465	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KLK36_02475	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KLK36_02480	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KLK36_02490	COG0463	Glycosyl transferase, family 2
KLK36_02495	COG0859	PFAM glycosyl transferase family 9
KLK36_02515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KLK36_02525	COG1519	Transferase
KLK36_02540	COG0859	PFAM glycosyl transferase family 9
KLK36_02545	COG3307	-O-antigen
KLK36_02555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KLK36_02635	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KLK36_02645	COG0463	Glycosyl transferase, family 2
KLK36_02675	COG3754	Rhamnan synthesis protein F
KLK36_02700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KLK36_02710	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KLK36_02730	COG1596	polysaccharide export
KLK36_02735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KLK36_02770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KLK36_02775	COG0438	transferase activity, transferring glycosyl groups
KLK36_02790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KLK36_02795	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KLK36_02805	COG0668	transmembrane transport
KLK36_02810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KLK36_02815	COG3068	Protein conserved in bacteria
KLK36_02820	COG2852	Protein conserved in bacteria
KLK36_02825	COG1253	flavin adenine dinucleotide binding
KLK36_02830	COG0776	regulation of translation
KLK36_02840	COG0151	Belongs to the GarS family
KLK36_02845	COG0138	bifunctional purine biosynthesis protein purh
KLK36_02860	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KLK36_02865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KLK36_02870	COG2264	protein methyltransferase activity
KLK36_02875	COG0439	Biotin carboxylase
KLK36_02880	COG0511	ligase activity, forming carbon-carbon bonds
KLK36_02885	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KLK36_02890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KLK36_02905	COG2814	Major facilitator Superfamily
KLK36_02915	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KLK36_02935	COG4232	protein-disulfide reductase activity
KLK36_02940	COG1438	arginine binding
KLK36_02945	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
KLK36_02950	COG0540	Belongs to the ATCase OTCase family
KLK36_02960	COG0549	Belongs to the carbamate kinase family
KLK36_02970	COG1288	antiporter activity
KLK36_02975	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KLK36_02980	COG1027	Aspartate ammonia-lyase
KLK36_02990	COG1278	Cold shock
KLK36_02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KLK36_03000	COG2205	protein histidine kinase activity
KLK36_03005	COG0745	RESPONSE REGULATOR receiver
KLK36_03015	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KLK36_03020	COG0205	6-phosphofructokinase activity
KLK36_03025	COG1494	fructose-1,6-bisphosphatase
KLK36_03030	COG3074	FtsZ-dependent cytokinesis
KLK36_03035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KLK36_03040	COG0460	homoserine dehydrogenase
KLK36_03040	COG0527	aspartate kinase activity
KLK36_03045	COG0626	cystathionine gamma-synthase activity
KLK36_03055	COG0281	malic enzyme
KLK36_03065	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KLK36_03070	COG1609	Transcriptional regulator
KLK36_03080	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KLK36_03090	COG1575	Belongs to the MenA family. Type 1 subfamily
KLK36_03095	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KLK36_03100	COG0534	Mate efflux family protein
KLK36_03130	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KLK36_03135	COG0459	protein refolding
KLK36_03150	COG1509	lysine 2,3-aminomutase activity
KLK36_03155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KLK36_03165	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KLK36_03170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KLK36_03175	COG1053	succinate dehydrogenase
KLK36_03180	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KLK36_03185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KLK36_03195	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KLK36_03200	COG1045	serine acetyltransferase
KLK36_03210	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KLK36_03220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KLK36_03225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KLK36_03230	COG0137	argininosuccinate synthase activity
KLK36_03235	COG0165	Argininosuccinate lyase
KLK36_03235	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KLK36_03245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KLK36_03250	COG0678	peroxiredoxin activity
KLK36_03250	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KLK36_03290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KLK36_03295	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KLK36_03305	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KLK36_03310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KLK36_03315	COG0546	phosphoglycolate phosphatase activity
KLK36_03320	COG0180	Tryptophanyl-tRNA synthetase
KLK36_03335	COG0583	DNA-binding transcription factor activity
KLK36_03345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KLK36_03360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KLK36_03380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KLK36_03405	COG0488	(ABC) transporter
KLK36_03420	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KLK36_03425	COG1047	Peptidyl-prolyl cis-trans
KLK36_03435	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KLK36_03440	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KLK36_03445	COG0557	exoribonuclease II activity
KLK36_03450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLK36_03455	COG0051	transcription antitermination factor activity, RNA binding
KLK36_03460	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KLK36_03465	COG0088	Forms part of the polypeptide exit tunnel
KLK36_03480	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KLK36_03495	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KLK36_03505	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KLK36_03515	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KLK36_03520	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KLK36_03525	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KLK36_03530	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KLK36_03535	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KLK36_03550	COG1841	ribosomal large subunit assembly
KLK36_03555	COG0200	Binds to the 23S rRNA
KLK36_03560	COG0201	protein transport
KLK36_03565	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KLK36_03570	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KLK36_03575	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KLK36_03580	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KLK36_03585	COG0202	RNA polymerase activity
KLK36_03590	COG0203	ribosomal protein L17
KLK36_03595	COG0545	Peptidyl-prolyl cis-trans isomerase
KLK36_03605	COG2153	protein acetylation
KLK36_03610	COG0513	Belongs to the DEAD box helicase family
KLK36_03650	COG0737	Belongs to the 5'-nucleotidase family
KLK36_03655	COG1648	precorrin-2 dehydrogenase activity
KLK36_03655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KLK36_03660	COG0175	sulfate reduction
KLK36_03665	COG2895	sulfate adenylyltransferase (ATP) activity
KLK36_03670	COG0529	Catalyzes the synthesis of activated sulfate
KLK36_03705	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
KLK36_03710	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KLK36_03725	COG2105	PFAM AIG2 family protein
KLK36_03730	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KLK36_03735	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KLK36_03740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KLK36_03745	COG0163	prenyltransferase activity
KLK36_03755	COG1178	ABC-type Fe3 transport system permease component
KLK36_03760	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KLK36_03765	COG3028	Belongs to the UPF0307 family
KLK36_03770	COG0312	modulator of DNA gyrase
KLK36_03775	COG2239	Acts as a magnesium transporter
KLK36_03780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KLK36_03785	COG1660	Displays ATPase and GTPase activities
KLK36_03790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KLK36_03795	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KLK36_03810	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KLK36_03820	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KLK36_03825	COG0517	IMP dehydrogenase activity
KLK36_03825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KLK36_03835	COG1127	ABC transporter
KLK36_03840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KLK36_03845	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KLK36_03850	COG2854	intermembrane phospholipid transfer
KLK36_03860	COG5007	Belongs to the BolA IbaG family
KLK36_03865	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KLK36_03885	COG0251	oxidation-reduction process
KLK36_03890	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
KLK36_03920	COG0564	pseudouridine synthase activity
KLK36_03925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLK36_03930	COG0525	valine-tRNA ligase activity
KLK36_03935	COG2927	DNA polymerase III (CHI subunit)
KLK36_03940	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KLK36_03945	COG0795	lipopolysaccharide-transporting ATPase activity
KLK36_03950	COG0795	lipopolysaccharide-transporting ATPase activity
KLK36_04010	COG0066	3-isopropylmalate dehydratase activity
KLK36_04020	COG0473	3-isopropylmalate dehydrogenase activity
KLK36_04045	COG1022	Amp-dependent synthetase and ligase
KLK36_04050	COG0028	Belongs to the TPP enzyme family
KLK36_04060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KLK36_04070	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KLK36_04080	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KLK36_04085	COG3079	Belongs to the UPF0149 family
KLK36_04090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KLK36_04095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KLK36_04110	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KLK36_04120	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KLK36_04125	COG1595	DNA-templated transcription, initiation
KLK36_04145	COG0481	GTPase activity
KLK36_04165	COG1381	Involved in DNA repair and RecF pathway recombination
KLK36_04170	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KLK36_04175	COG0736	holo-[acyl-carrier-protein] synthase activity
KLK36_04180	COG4999	Histidine kinase
KLK36_04180	COG3850	Histidine kinase
KLK36_04180	COG2205	protein histidine kinase activity
KLK36_04180	COG3437	response regulator, receiver
KLK36_04185	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KLK36_04190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KLK36_04200	COG0504	CTP synthase activity
KLK36_04210	COG0617	tRNA 3'-terminal CCA addition
KLK36_04215	COG3409	Peptidoglycan-binding domain 1 protein
KLK36_04215	COG3267	Type II secretory pathway component ExeA
KLK36_04225	COG4991	sh3 domain protein
KLK36_04230	COG0306	phosphate transporter
KLK36_04235	COG1392	Phosphate transport regulator
KLK36_04240	COG3025	triphosphatase activity
KLK36_04260	COG1538	Outer membrane efflux protein
KLK36_04265	COG0494	nUDIX hydrolase
KLK36_04270	COG3151	Protein conserved in bacteria
KLK36_04280	COG3150	esterase
KLK36_04285	COG0187	DNA topoisomerase II activity
KLK36_04290	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KLK36_04295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KLK36_04300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KLK36_04305	COG3105	Protein conserved in bacteria
KLK36_04310	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KLK36_04315	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KLK36_04325	COG0723	plastoquinol--plastocyanin reductase activity
KLK36_04330	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KLK36_04335	COG2857	Cytochrome c1
KLK36_04340	COG0625	glutathione transferase activity
KLK36_04345	COG2969	positive regulation of protein catabolic process
KLK36_04355	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KLK36_04360	COG0792	nuclease activity
KLK36_04365	COG3107	peptidoglycan biosynthetic process
KLK36_04370	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KLK36_04380	COG0275	rRNA processing
KLK36_04385	COG3116	cell division
KLK36_04395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KLK36_04400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KLK36_04415	COG0772	Belongs to the SEDS family
KLK36_04420	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KLK36_04425	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KLK36_04430	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KLK36_04435	COG0849	cell division
KLK36_04445	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KLK36_04460	COG0494	nUDIX hydrolase
KLK36_04465	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KLK36_04470	COG0505	Belongs to the CarA family
KLK36_04480	COG0730	response to heat
KLK36_04485	COG0583	DNA-binding transcription factor activity
KLK36_04490	COG2860	membrane
KLK36_04495	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KLK36_04505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KLK36_04515	COG0493	'glutamate synthase
KLK36_04530	COG0067	glutamate synthase
KLK36_04530	COG0069	glutamate synthase activity
KLK36_04530	COG0070	glutamate synthase
KLK36_04540	COG0784	Response regulator, receiver
KLK36_04540	COG5002	protein histidine kinase activity
KLK36_04540	COG2198	Histidine kinase
KLK36_04550	COG0745	RESPONSE REGULATOR receiver
KLK36_04555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KLK36_04575	COG0083	homoserine kinase activity
KLK36_04580	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KLK36_04585	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
KLK36_04590	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KLK36_04595	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KLK36_04610	COG1115	amino acid carrier protein
KLK36_04615	COG3022	response to hydroperoxide
KLK36_04625	COG0084	hydrolase, TatD family'
KLK36_04630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KLK36_04635	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KLK36_04640	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KLK36_04645	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KLK36_04650	COG0813	purine-nucleoside phosphorylase activity
KLK36_04660	COG0560	Phosphoserine phosphatase
KLK36_04670	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KLK36_04680	COG4628	conserved protein (DUF2132)
KLK36_04685	COG1022	Amp-dependent synthetase and ligase
KLK36_04690	COG0784	Response regulator, receiver
KLK36_04690	COG3437	response regulator, receiver
KLK36_04705	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KLK36_04710	COG1085	galactose-1-phosphate uridylyltransferase
KLK36_04720	COG1609	Transcriptional regulator
KLK36_04750	COG2171	N-acyltransferase activity
KLK36_04755	COG3141	response to X-ray
KLK36_04775	COG1074	ATP-dependent DNA helicase activity
KLK36_04785	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KLK36_04785	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KLK36_04795	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KLK36_04805	COG2166	iron-sulfur cluster assembly
KLK36_04810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KLK36_04820	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KLK36_04835	COG1595	DNA-templated transcription, initiation
KLK36_04845	COG2211	Major facilitator Superfamily
KLK36_04865	COG0271	Belongs to the BolA IbaG family
KLK36_04900	COG1477	protein flavinylation
KLK36_04910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KLK36_04925	COG0733	neurotransmitter:sodium symporter activity
KLK36_04935	COG0189	ligase activity
KLK36_04940	COG4067	protein conserved in archaea
KLK36_04940	COG0189	ligase activity
KLK36_04945	COG2195	Cleaves the N-terminal amino acid of tripeptides
KLK36_04950	COG2252	PERMEase
KLK36_04955	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KLK36_04970	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KLK36_04975	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KLK36_04980	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KLK36_04985	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KLK36_04985	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KLK36_05005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KLK36_05015	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KLK36_05025	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KLK36_05030	COG0024	Methionine aminopeptidase
KLK36_05035	COG0052	Belongs to the universal ribosomal protein uS2 family
KLK36_05040	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KLK36_05050	COG0233	cytoplasmic translational termination
KLK36_05060	COG0575	Belongs to the CDS family
KLK36_05070	COG0750	zinc metalloprotease
KLK36_05080	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
KLK36_05085	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KLK36_05090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KLK36_05100	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KLK36_05110	COG0587	DNA-directed DNA polymerase activity
KLK36_05120	COG0037	tRNA processing
KLK36_05130	COG0347	Belongs to the P(II) protein family
KLK36_05135	COG3021	interspecies interaction between organisms
KLK36_05145	COG0741	lytic transglycosylase activity
KLK36_05145	COG1388	LysM domain
KLK36_05150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KLK36_05160	COG0328	RNA-DNA hybrid ribonuclease activity
KLK36_05180	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KLK36_05185	COG0121	glutamine amidotransferase
KLK36_05190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KLK36_05200	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KLK36_05205	COG1187	pseudouridine synthase activity
KLK36_05275	COG2747	anti-sigma28 factor FlgM
KLK36_05285	COG0784	Response regulator, receiver
KLK36_05285	COG0835	chemotaxis
KLK36_05295	COG1815	bacterial-type flagellum-dependent cell motility
KLK36_05310	COG1749	Flagellar hook protein flgE
KLK36_05315	COG4787	bacterial-type flagellum-dependent cell motility
KLK36_05325	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KLK36_05330	COG1706	bacterial-type flagellum-dependent cell motility
KLK36_05335	COG1705	Flagellar rod assembly protein muramidase FlgJ
KLK36_05335	COG3951	Flagellar rod assembly protein muramidase FlgJ
KLK36_05345	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KLK36_05435	COG0193	aminoacyl-tRNA hydrolase activity
KLK36_05440	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLK36_05450	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KLK36_05455	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KLK36_05460	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KLK36_05465	COG2890	protein-(glutamine-N5) methyltransferase activity
KLK36_05470	COG3094	Invasion gene expression up-regulator, SirB
KLK36_05475	COG2912	Transglutaminase-like superfamily
KLK36_05480	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KLK36_05495	COG2233	PERMEase
KLK36_05515	COG1393	Belongs to the ArsC family
KLK36_05540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KLK36_05555	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KLK36_05575	COG1393	Belongs to the ArsC family
KLK36_05605	COG2837	iron assimilation
KLK36_05630	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KLK36_05640	COG1516	flagellar protein fliS
KLK36_05660	COG1677	Flagellar hook-basal body complex protein FliE
KLK36_05670	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KLK36_05720	COG1987	bacterial-type flagellum assembly
KLK36_05725	COG1684	flagellar biosynthetic protein fliR
KLK36_05735	COG2840	Smr protein MutS2
KLK36_05745	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KLK36_05750	COG2860	membrane
KLK36_05755	COG3101	peptidyl-lysine hydroxylation
KLK36_05770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KLK36_05770	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KLK36_05775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KLK36_05780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KLK36_05790	COG0735	belongs to the Fur family
KLK36_05800	COG0583	DNA-binding transcription factor activity
KLK36_05810	COG1346	cytolysis
KLK36_05825	COG0596	Alpha beta hydrolase
KLK36_05830	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
KLK36_05835	COG0033	Phosphoglucomutase
KLK36_05845	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KLK36_05860	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KLK36_05875	COG0567	Dehydrogenase, E1 component
KLK36_05880	COG0508	dehydrogenase complex catalyzes the overall conversion of
KLK36_05895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KLK36_05900	COG1121	(ABC) transporter
KLK36_05905	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KLK36_05915	COG1918	ferrous iron import across plasma membrane
KLK36_05940	COG3102	Protein conserved in bacteria
KLK36_05950	COG2062	phosphohistidine phosphatase, SixA
KLK36_05980	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KLK36_05985	COG2198	Histidine kinase
KLK36_05985	COG0784	Response regulator, receiver
KLK36_05985	COG0643	Histidine kinase
KLK36_05990	COG2201	protein-glutamate methylesterase activity
KLK36_05995	COG1192	Involved in chromosome partitioning
KLK36_06005	COG0835	chemotaxis
KLK36_06015	COG4133	protoheme IX ABC transporter activity
KLK36_06020	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KLK36_06025	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KLK36_06035	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KLK36_06040	COG1138	Cytochrome C-type biogenesis protein
KLK36_06045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KLK36_06060	COG2853	Lipoprotein
KLK36_06080	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KLK36_06115	COG3083	sulfuric ester hydrolase activity
KLK36_06120	COG3082	Protein of unknown function (DUF1414)
KLK36_06135	COG1757	Na H antiporter
KLK36_06140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KLK36_06145	COG2095	MarC family integral membrane protein
KLK36_06150	COG1012	belongs to the aldehyde dehydrogenase family
KLK36_06150	COG1454	alcohol dehydrogenase
KLK36_06160	COG1530	ribonuclease E activity
KLK36_06165	COG0564	pseudouridine synthase activity
KLK36_06170	COG0424	maF-like protein
KLK36_06175	COG1399	metal-binding, possibly nucleic acid-binding protein
KLK36_06190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KLK36_06215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KLK36_06220	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KLK36_06225	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KLK36_06230	COG0470	DNA polymerase III
KLK36_06235	COG0084	hydrolase, TatD family'
KLK36_06240	COG1263	PTS System
KLK36_06240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KLK36_06250	COG0733	neurotransmitter:sodium symporter activity
KLK36_06265	COG4667	esterase of the alpha-beta hydrolase superfamily
KLK36_06275	COG1940	carbohydrate kinase activity
KLK36_06280	COG0784	Response regulator, receiver
KLK36_06280	COG0835	chemotaxis
KLK36_06305	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KLK36_06310	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KLK36_06315	COG0436	Aminotransferase
KLK36_06320	COG1169	isochorismate synthase
KLK36_06325	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KLK36_06335	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KLK36_06385	COG1522	sequence-specific DNA binding
KLK36_06390	COG1946	Acyl-CoA thioesterase
KLK36_06395	COG3126	Type III secretion system lipoprotein chaperone (YscW)
KLK36_06410	COG3706	GGDEF domain
KLK36_06435	COG1022	Amp-dependent synthetase and ligase
KLK36_06445	COG4221	oxidoreductase activity
KLK36_06455	COG0745	RESPONSE REGULATOR receiver
KLK36_06460	COG0642	Histidine kinase
KLK36_06490	COG5002	protein histidine kinase activity
KLK36_06490	COG3850	Histidine kinase
KLK36_06510	COG0129	dihydroxy-acid dehydratase activity
KLK36_06515	COG3265	gluconokinase activity
KLK36_06520	COG2610	gluconate transmembrane transporter activity
KLK36_06525	COG0800	Aldolase
KLK36_06550	COG1028	Short-chain dehydrogenase reductase Sdr
KLK36_06555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KLK36_06560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KLK36_06590	COG1216	Glycosyl transferase, family 2
KLK36_06610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KLK36_06615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KLK36_06640	COG0784	Response regulator, receiver
KLK36_06640	COG5002	protein histidine kinase activity
KLK36_06655	COG0601	transmembrane transport
KLK36_06660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLK36_06675	COG0435	Glutathione S-transferase
KLK36_06680	COG0280	phosphate acetyltransferase
KLK36_06680	COG0857	belongs to the CobB CobQ family
KLK36_06685	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KLK36_06690	COG3092	negative regulation of chromosome organization
KLK36_06700	COG4120	Belongs to the binding-protein-dependent transport system permease family
KLK36_06710	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KLK36_06715	COG0653	protein targeting
KLK36_06720	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KLK36_06725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KLK36_06735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KLK36_06740	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KLK36_06745	COG0156	8-amino-7-oxononanoate synthase activity
KLK36_06750	COG2226	methyltransferase
KLK36_06755	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KLK36_06770	COG2186	Transcriptional regulator
KLK36_06810	COG3150	esterase
KLK36_06815	COG1252	NADH dehydrogenase
KLK36_06830	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KLK36_06840	COG4591	ABC-type transport system involved in lipoprotein release permease component
KLK36_06845	COG1136	(ABC) transporter
KLK36_06850	COG4591	ABC-type transport system involved in lipoprotein release permease component
KLK36_06860	COG2333	competence protein COMEC
KLK36_06860	COG0658	competence protein
KLK36_06865	COG1132	(ABC) transporter
KLK36_06880	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KLK36_06890	COG2719	SpoVR family
KLK36_06895	COG2718	Belongs to the UPF0229 family
KLK36_06900	COG2766	serine protein kinase
KLK36_06905	COG3013	Belongs to the UPF0304 family
KLK36_06915	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KLK36_06930	COG1882	Formate acetyltransferase
KLK36_06955	COG4160	amino acid transport
KLK36_06960	COG0708	Exodeoxyribonuclease III
KLK36_06965	COG0840	transmembrane signaling receptor activity
KLK36_06975	COG3923	Primosomal replication protein n
KLK36_06985	COG1199	ATP-dependent helicase activity
KLK36_06995	COG3012	SEC-C Motif Domain Protein
KLK36_07000	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KLK36_07005	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KLK36_07010	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KLK36_07015	COG0215	cysteine-tRNA ligase activity
KLK36_07020	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KLK36_07030	COG2255	four-way junction helicase activity
KLK36_07035	COG1271	oxidase subunit
KLK36_07040	COG1294	oxidase, subunit
KLK36_07045	COG4890	Cyd operon protein YbgT
KLK36_07050	COG3790	cyd operon protein YbgE
KLK36_07055	COG0824	Thioesterase
KLK36_07060	COG0811	peptide transport
KLK36_07080	COG2885	chlorophyll binding
KLK36_07085	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KLK36_07090	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KLK36_07095	COG2433	Pfam Transposase IS66
KLK36_07130	COG0582	viral genome integration into host DNA
KLK36_07220	COG2404	hydrolase activity, acting on ester bonds
KLK36_07250	COG3081	Nucleoid-associated protein
KLK36_07340	COG1403	HNH endonuclease
KLK36_07415	COG0740	serine-type endopeptidase activity
KLK36_07585	COG1960	acyl-CoA dehydrogenase activity
KLK36_07590	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KLK36_07620	COG0247	lactate metabolic process
KLK36_07620	COG0277	FAD linked oxidase domain protein
KLK36_07635	COG2986	histidine ammonia-lyase
KLK36_07645	COG0010	Belongs to the arginase family
KLK36_07660	COG3097	Belongs to the UPF0267 family
KLK36_07665	COG3099	Belongs to the UPF0263 family
KLK36_07670	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KLK36_07680	COG0417	DNA replication proofreading
KLK36_07690	COG0322	excinuclease ABC activity
KLK36_07730	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KLK36_07735	COG0072	phenylalanine-tRNA ligase activity
KLK36_07735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KLK36_07740	COG0776	regulation of translation
KLK36_07750	COG0500	methyltransferase
KLK36_07765	COG5001	Diguanylate cyclase
KLK36_07775	COG1346	cytolysis
KLK36_07780	COG1380	Effector of murein hydrolase LrgA
KLK36_07785	COG2925	Exonuclease
KLK36_07790	COG1823	symporter activity
KLK36_07795	COG0702	epimerase
KLK36_07825	COG2994	toxin metabolic process
KLK36_07840	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KLK36_07855	COG2988	succinylglutamate desuccinylase activity
KLK36_07860	COG4139	cobalamin transport
KLK36_07865	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
KLK36_07885	COG0583	DNA-binding transcription factor activity
KLK36_07895	COG1451	nucleotide metabolic process
KLK36_07910	COG3063	Type IV pilus biogenesis stability protein PilW
KLK36_07935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KLK36_07950	COG3290	protein histidine kinase activity
KLK36_07955	COG4565	transcriptional regulatory protein
KLK36_07965	COG0784	Response regulator, receiver
KLK36_07965	COG0835	chemotaxis
KLK36_08005	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KLK36_08080	COG1181	Belongs to the D-alanine--D-alanine ligase family
KLK36_08100	COG1716	ATPase activity
KLK36_08125	COG0515	serine threonine protein kinase
KLK36_08125	COG3064	Membrane
KLK36_08125	COG4991	sh3 domain protein
KLK36_08190	COG0251	oxidation-reduction process
KLK36_08200	COG1294	oxidase, subunit
KLK36_08220	COG3220	belongs to the UPF0276 family
KLK36_08245	COG0840	transmembrane signaling receptor activity
KLK36_08255	COG2200	EAL domain
KLK36_08265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KLK36_08265	COG1263	PTS System
KLK36_08275	COG1621	beta-fructofuranosidase activity
KLK36_08280	COG0840	transmembrane signaling receptor activity
KLK36_08290	COG1054	Belongs to the UPF0176 family
KLK36_08300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KLK36_08310	COG0848	biopolymer transport protein
KLK36_08315	COG0811	peptide transport
KLK36_08320	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KLK36_08325	COG3721	Heme iron utilization protein
KLK36_08335	COG4771	TonB-dependent receptor
KLK36_08335	COG1629	transport
KLK36_08340	COG1940	carbohydrate kinase activity
KLK36_08375	COG3108	Peptidase M15
KLK36_08380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KLK36_08395	COG1846	Transcriptional regulator
KLK36_08400	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KLK36_08415	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KLK36_08420	COG1448	Aminotransferase
KLK36_08425	COG2770	Histidine kinase
KLK36_08425	COG3437	response regulator, receiver
KLK36_08430	COG0840	transmembrane signaling receptor activity
KLK36_08435	COG0745	RESPONSE REGULATOR receiver
KLK36_08445	COG0643	Histidine kinase
KLK36_08445	COG2198	Histidine kinase
KLK36_08455	COG0835	chemotaxis
KLK36_08465	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KLK36_08470	COG2201	protein-glutamate methylesterase activity
KLK36_08480	COG0017	Asparaginyl-tRNA synthetase
KLK36_08485	COG0840	transmembrane signaling receptor activity
KLK36_08490	COG0720	synthase
KLK36_08495	COG2356	endonuclease I
KLK36_08505	COG1760	l-serine dehydratase
KLK36_08510	COG0814	amino acid
KLK36_08515	COG0494	nUDIX hydrolase
KLK36_08520	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KLK36_08535	COG3106	COG3106 Predicted ATPase
KLK36_08540	COG3768	UPF0283 membrane protein
KLK36_08570	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KLK36_08580	COG0471	metal ion transport
KLK36_08585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KLK36_08585	COG4191	Histidine kinase
KLK36_08595	COG1278	Cold shock
KLK36_08600	COG3005	denitrification pathway
KLK36_08605	COG0243	molybdopterin cofactor binding
KLK36_08610	COG0513	Belongs to the DEAD box helicase family
KLK36_08615	COG2723	6-phospho-beta-galactosidase activity
KLK36_08620	COG1609	Transcriptional regulator
KLK36_08685	COG1643	Atp-dependent helicase
KLK36_08700	COG0477	Major facilitator Superfamily
KLK36_08710	COG0673	inositol 2-dehydrogenase activity
KLK36_08715	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KLK36_08720	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KLK36_08720	COG0517	IMP dehydrogenase activity
KLK36_08725	COG2176	DNA-directed DNA polymerase activity
KLK36_08735	COG3718	enzyme involved in inositol metabolism
KLK36_08740	COG3962	Belongs to the TPP enzyme family
KLK36_08745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KLK36_08765	COG0673	inositol 2-dehydrogenase activity
KLK36_08770	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KLK36_08830	COG1204	response to ionizing radiation
KLK36_08850	COG2433	Pfam Transposase IS66
KLK36_08860	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KLK36_08865	COG1280	lysine exporter protein (LysE YggA)
KLK36_08870	COG1115	amino acid carrier protein
KLK36_08885	COG2195	Cleaves the N-terminal amino acid of tripeptides
KLK36_08895	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KLK36_08905	COG0625	glutathione transferase activity
KLK36_08935	COG0811	peptide transport
KLK36_08940	COG0811	peptide transport
KLK36_08945	COG0848	biopolymer transport protein
KLK36_08965	COG1793	dna ligase
KLK36_08980	COG3001	Fructosamine kinase
KLK36_08990	COG0791	NLP P60 protein
KLK36_08995	COG0840	transmembrane signaling receptor activity
KLK36_09005	COG3148	PFAM DTW domain containing protein
KLK36_09010	COG1940	carbohydrate kinase activity
KLK36_09020	COG1763	Mo-molybdopterin cofactor biosynthetic process
KLK36_09025	COG0746	molybdenum cofactor guanylyltransferase activity
KLK36_09030	COG3842	ATPase activity
KLK36_09040	COG1840	ABC-type Fe3 transport system, periplasmic component
KLK36_09045	COG2271	Major facilitator Superfamily
KLK36_09055	COG2197	response regulator
KLK36_09060	COG0488	(ABC) transporter
KLK36_09065	COG0004	ammonium transporteR
KLK36_09070	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KLK36_09080	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KLK36_09085	COG1177	transmembrane transport
KLK36_09090	COG1176	ABC-type spermidine putrescine transport system, permease component I
KLK36_09095	COG3842	ATPase activity
KLK36_09120	COG0589	response to stress
KLK36_09125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KLK36_09140	COG2217	Heavy metal translocating P-type atpase
KLK36_09150	COG2010	Cytochrome c
KLK36_09185	COG3120	sequence-specific DNA binding
KLK36_09190	COG1067	ATP-dependent peptidase activity
KLK36_09195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KLK36_09210	COG0488	(ABC) transporter
KLK36_09230	COG0167	dihydroorotate dehydrogenase activity
KLK36_09260	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
KLK36_09265	COG1956	GAF domain-containing protein
KLK36_09270	COG1132	(ABC) transporter
KLK36_09275	COG2995	paraquat-inducible protein a
KLK36_09280	COG3008	intermembrane lipid transfer
KLK36_09290	COG2996	Protein conserved in bacteria
KLK36_09310	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KLK36_09315	COG1666	GTP binding
KLK36_09325	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KLK36_09325	COG1648	precorrin-2 dehydrogenase activity
KLK36_09330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KLK36_09335	COG4597	amino acid ABC transporter
KLK36_09340	COG0765	amino acid transport
KLK36_09345	COG1126	abc transporter atp-binding protein
KLK36_09350	COG0670	Belongs to the BI1 family
KLK36_09360	COG1254	Belongs to the acylphosphatase family
KLK36_09405	COG0602	queuosine metabolic process
KLK36_09410	COG0561	phosphatase activity
KLK36_09430	COG2828	Protein conserved in bacteria
KLK36_09440	COG0372	Belongs to the citrate synthase family
KLK36_09445	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KLK36_09475	COG0745	RESPONSE REGULATOR receiver
KLK36_09485	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KLK36_09490	COG1902	pentaerythritol trinitrate reductase activity
KLK36_09505	COG1129	ABC transporter
KLK36_09525	COG1342	Belongs to the UPF0251 family
KLK36_09535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KLK36_09545	COG2207	Transcriptional regulator
KLK36_09550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KLK36_09550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KLK36_09550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KLK36_09575	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KLK36_09585	COG3051	citrate lyase alpha subunit
KLK36_09590	COG2301	Belongs to the HpcH HpaI aldolase family
KLK36_09600	COG4565	transcriptional regulatory protein
KLK36_09610	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KLK36_09615	COG5016	pyruvate
KLK36_09615	COG0511	ligase activity, forming carbon-carbon bonds
KLK36_09650	COG0840	transmembrane signaling receptor activity
KLK36_09660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KLK36_09665	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLK36_09670	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLK36_09735	COG4181	ATPase activity
KLK36_09740	COG0534	Mate efflux family protein
KLK36_09745	COG0702	epimerase
KLK36_09755	COG2814	Major facilitator Superfamily
KLK36_09760	COG1187	pseudouridine synthase activity
KLK36_09765	COG1061	Type III restriction enzyme res subunit
KLK36_09780	COG2205	protein histidine kinase activity
KLK36_09785	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KLK36_09800	COG0513	Belongs to the DEAD box helicase family
KLK36_09830	COG3313	Fe-S protein
KLK36_09845	COG4135	transport system, permease component
KLK36_09855	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KLK36_09870	COG0564	pseudouridine synthase activity
KLK36_09875	COG0733	neurotransmitter:sodium symporter activity
KLK36_09890	COG0519	Catalyzes the synthesis of GMP from XMP
KLK36_09905	COG1842	Phage shock protein A
KLK36_09925	COG4171	peptide transport system, permease
KLK36_09935	COG4172	Belongs to the ABC transporter superfamily
KLK36_09950	COG1227	inorganic diphosphatase activity
KLK36_09960	COG0243	molybdopterin cofactor binding
KLK36_09965	COG3005	denitrification pathway
KLK36_09970	COG4459	periplasmic nitrate reductase
KLK36_09975	COG2116	formate transmembrane transporter activity
KLK36_10000	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KLK36_10005	COG1435	thymidine kinase activity
KLK36_10010	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KLK36_10015	COG1801	Protein of unknown function DUF72
KLK36_10025	COG4106	trans-aconitate 2-methyltransferase activity
KLK36_10030	COG0500	methyltransferase
KLK36_10035	COG4067	protein conserved in archaea
KLK36_10035	COG0189	ligase activity
KLK36_10050	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KLK36_10065	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KLK36_10070	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KLK36_10075	COG0745	RESPONSE REGULATOR receiver
KLK36_10085	COG1609	Transcriptional regulator
KLK36_10090	COG3070	regulator of competence-specific genes
KLK36_10110	COG0297	glycogen (starch) synthase activity
KLK36_10115	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KLK36_10120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KLK36_10135	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KLK36_10140	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KLK36_10145	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KLK36_10150	COG0542	response to heat
KLK36_10155	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KLK36_10160	COG1278	Cold shock
KLK36_10170	COG1187	pseudouridine synthase activity
KLK36_10175	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KLK36_10175	COG0140	phosphoribosyl-ATP diphosphatase activity
KLK36_10180	COG0107	imidazoleglycerol-phosphate synthase activity
KLK36_10185	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KLK36_10190	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KLK36_10200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KLK36_10205	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KLK36_10210	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KLK36_10215	COG1757	Na H antiporter
KLK36_10220	COG2916	Histone family protein nucleoid-structuring protein H-NS
KLK36_10225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KLK36_10235	COG0482	sulfurtransferase activity
KLK36_10240	COG2915	High frequency lysogenization protein hflD homolog
KLK36_10245	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KLK36_10250	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KLK36_10260	COG4191	Histidine kinase
KLK36_10260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KLK36_10275	COG3070	regulator of competence-specific genes
KLK36_10285	COG2431	L-lysine efflux transmembrane transporter activity
KLK36_10295	COG0076	glutamate decarboxylase activity
KLK36_10300	COG1737	Transcriptional regulator
KLK36_10310	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KLK36_10315	COG2985	domain, Protein
KLK36_10315	COG3273	potassium ion transport
KLK36_10320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KLK36_10330	COG0281	malic enzyme
KLK36_10340	COG2949	membrane
KLK36_10360	COG0492	ferredoxin-NADP+ reductase activity
KLK36_10365	COG4988	ABC transporter
KLK36_10385	COG1595	DNA-templated transcription, initiation
KLK36_10400	COG1187	pseudouridine synthase activity
KLK36_10405	COG0009	L-threonylcarbamoyladenylate synthase
KLK36_10410	COG0613	PHP domain protein
KLK36_10420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KLK36_10430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KLK36_10435	COG0135	phosphoribosylanthranilate isomerase activity
KLK36_10435	COG0134	indole-3-glycerol-phosphate synthase activity
KLK36_10440	COG0133	tryptophan synthase activity
KLK36_10445	COG0159	tryptophan synthase activity
KLK36_10470	COG2350	Protein conserved in bacteria
KLK36_10480	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KLK36_10500	COG2203	Gaf domain
KLK36_10500	COG2200	EAL domain
KLK36_10500	COG2199	diguanylate cyclase activity
KLK36_10510	COG1032	radical SAM domain protein
KLK36_10520	COG2268	Band 7 protein
KLK36_10530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KLK36_10545	COG0300	oxidoreductase activity
KLK36_10555	COG0501	Belongs to the peptidase M48B family
KLK36_10565	COG1674	ftsk spoiiie
KLK36_10570	COG1522	sequence-specific DNA binding
KLK36_10575	COG0686	Belongs to the AlaDH PNT family
KLK36_10585	COG0583	DNA-binding transcription factor activity
KLK36_10600	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KLK36_10605	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
KLK36_10610	COG0776	regulation of translation
KLK36_10615	COG0539	negative regulation of cytoplasmic translation
KLK36_10620	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KLK36_10625	COG1555	photosystem II stabilization
KLK36_10630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KLK36_10635	COG0776	regulation of translation
KLK36_10640	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KLK36_10645	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KLK36_10655	COG0544	peptidyl-prolyl cis-trans isomerase activity
KLK36_10675	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KLK36_10680	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KLK36_10685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KLK36_10690	COG1653	transport
KLK36_10695	COG2205	protein histidine kinase activity
KLK36_10705	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KLK36_10710	COG1760	l-serine dehydratase
KLK36_10720	COG0513	Belongs to the DEAD box helicase family
KLK36_10730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KLK36_10745	COG4628	conserved protein (DUF2132)
KLK36_10775	COG0583	DNA-binding transcription factor activity
KLK36_10780	COG2951	lytic endotransglycosylase activity
KLK36_10785	COG3100	YcgL domain-containing protein
KLK36_10795	COG2894	cell division
KLK36_10800	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KLK36_10805	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KLK36_10810	COG0318	PFAM AMP-dependent synthetase and ligase
KLK36_10815	COG0596	Alpha beta hydrolase
KLK36_10830	COG1214	PFAM Peptidase M22, glycoprotease
KLK36_10845	COG0788	formyltetrahydrofolate deformylase activity
KLK36_10850	COG0446	pyridine nucleotide-disulphide oxidoreductase
KLK36_10850	COG1902	pentaerythritol trinitrate reductase activity
KLK36_10855	COG0616	signal peptide processing
KLK36_10860	COG0252	asparaginase activity
KLK36_10865	COG3139	Protein of unknown function (DUF1315)
KLK36_10875	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KLK36_10890	COG2226	methyltransferase
KLK36_10905	COG2983	Belongs to the UPF0260 family
KLK36_10915	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KLK36_10930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KLK36_10935	COG2832	Protein of unknown function (DUF454)
KLK36_10945	COG0583	DNA-binding transcription factor activity
KLK36_10950	COG0778	Nitroreductase
KLK36_10955	COG1250	3-hydroxyacyl-CoA dehydrogenase
KLK36_10955	COG1024	Enoyl-CoA hydratase
KLK36_10960	COG0183	Belongs to the thiolase family
KLK36_10965	COG1595	DNA-templated transcription, initiation
KLK36_10975	COG2067	long-chain fatty acid transport protein
KLK36_10980	COG2067	long-chain fatty acid transport protein
KLK36_10985	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
KLK36_10990	COG2982	Protein involved in outer membrane biogenesis
KLK36_10995	COG0572	uridine kinase
KLK36_11000	COG0489	protein tyrosine kinase activity
KLK36_11005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KLK36_11005	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KLK36_11015	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
KLK36_11025	COG0517	IMP dehydrogenase activity
KLK36_11025	COG0617	tRNA 3'-terminal CCA addition
KLK36_11025	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KLK36_11035	COG0314	molybdopterin synthase activity
KLK36_11050	COG0521	Mo-molybdopterin cofactor biosynthetic process
KLK36_11060	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KLK36_11065	COG2198	Histidine kinase
KLK36_11070	COG2204	response regulator
KLK36_11075	COG0556	nucleotide-excision repair
KLK36_11090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KLK36_11105	COG1021	2,3-dihydroxybenzoate-AMP ligase
KLK36_11110	COG1535	isochorismatase
KLK36_11110	COG3433	isochorismatase activity
KLK36_11140	COG2382	esterase
KLK36_11155	COG4657	Part of a membrane complex involved in electron transport
KLK36_11160	COG2878	Part of a membrane complex involved in electron transport
KLK36_11170	COG4658	electron transport chain
KLK36_11175	COG4659	FMN binding
KLK36_11180	COG4660	Part of a membrane complex involved in electron transport
KLK36_11185	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KLK36_11190	COG0346	lactoylglutathione lyase activity
KLK36_11200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KLK36_11205	COG2056	Na+-H+ antiporter family
KLK36_11210	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KLK36_11215	COG1286	toxin biosynthetic process
KLK36_11220	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KLK36_11225	COG0285	dihydrofolate synthase activity
KLK36_11230	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KLK36_11235	COG0101	tRNA pseudouridine synthase activity
KLK36_11245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KLK36_11250	COG1263	PTS System
KLK36_11250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KLK36_11250	COG2190	(PTS) system
KLK36_11260	COG1940	carbohydrate kinase activity
KLK36_11260	COG1846	Transcriptional regulator
KLK36_11265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KLK36_11265	COG4651	solute:proton antiporter activity
KLK36_11270	COG0367	asparagine synthase
KLK36_11280	COG3104	oligopeptide transport
KLK36_11285	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KLK36_11295	COG0326	Molecular chaperone. Has ATPase activity
KLK36_11300	COG3710	Transcriptional regulator
KLK36_11315	COG0622	Phosphoesterase
KLK36_11320	COG1090	epimerase
KLK36_11325	COG3118	belongs to the thioredoxin family
KLK36_11330	COG0330	HflC and HflK could
KLK36_11340	COG0789	Transcriptional regulator
KLK36_11360	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KLK36_11365	COG3115	cell septum assembly
KLK36_11370	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
KLK36_11375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KLK36_11380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KLK36_11390	COG2190	(PTS) system
KLK36_11395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KLK36_11405	COG1702	phosphate starvation-inducible protein PhoH
KLK36_11410	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KLK36_11415	COG4535	Mg2 and Co2 transporter CorC
KLK36_11420	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KLK36_11425	COG2888	peptidyl-tyrosine sulfation
KLK36_11435	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
KLK36_11440	COG1466	dna polymerase III delta subunit
KLK36_11445	COG0799	negative regulation of ribosome biogenesis
KLK36_11450	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KLK36_11455	COG0768	penicillin binding
KLK36_11460	COG0772	Belongs to the SEDS family
KLK36_11470	COG1686	Belongs to the peptidase S11 family
KLK36_11475	COG2921	Belongs to the UPF0250 family
KLK36_11480	COG0321	lipoyl(octanoyl) transferase activity
KLK36_11485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KLK36_11515	COG1596	polysaccharide export
KLK36_11520	COG0489	protein tyrosine kinase activity
KLK36_11545	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KLK36_11555	COG1045	serine acetyltransferase
KLK36_11595	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KLK36_11600	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KLK36_11605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KLK36_11610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KLK36_11660	COG0745	RESPONSE REGULATOR receiver
KLK36_11665	COG0366	Alpha amylase catalytic
KLK36_11670	COG1263	PTS System
KLK36_11670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KLK36_11685	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KLK36_11690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KLK36_11695	COG2011	ABC-type metal ion transport system permease component
KLK36_11700	COG1464	Belongs to the NlpA lipoprotein family
KLK36_11705	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
KLK36_11730	COG1611	Belongs to the LOG family
KLK36_11735	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KLK36_11740	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KLK36_11745	COG2363	Small membrane protein
KLK36_11750	COG0583	DNA-binding transcription factor activity
KLK36_11755	COG0301	tRNA thio-modification
KLK36_11755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KLK36_11765	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KLK36_11770	COG1722	exodeoxyribonuclease VII activity
KLK36_11775	COG0142	geranyltranstransferase activity
KLK36_11780	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KLK36_11785	COG0564	pseudouridine synthase activity
KLK36_11790	COG3098	single-species biofilm formation
KLK36_11820	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KLK36_11825	COG0254	rRNA binding
KLK36_11830	COG1720	tRNA m6t6A37 methyltransferase activity
KLK36_11835	COG0442	prolyl-tRNA aminoacylation
KLK36_11840	COG2979	Protein of unknown function (DUF533)
KLK36_11860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLK36_11860	COG0047	phosphoribosylformylglycinamidine synthase activity
KLK36_11865	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KLK36_11875	COG0583	DNA-binding transcription factor activity
KLK36_11885	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KLK36_11890	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KLK36_11920	COG0484	heat shock protein binding
KLK36_11925	COG0443	Heat shock 70 kDa protein
KLK36_11930	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KLK36_11940	COG3033	Beta-eliminating lyase
KLK36_11945	COG0497	DNA recombination
KLK36_11950	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KLK36_11955	COG2914	Belongs to the UPF0125 (RnfH) family
KLK36_11960	COG2867	negative regulation of translational initiation
KLK36_12005	COG1715	Restriction endonuclease
KLK36_12020	COG2003	Belongs to the UPF0758 family
KLK36_12165	COG3964	amidohydrolase
KLK36_12180	COG3711	transcriptional antiterminator
KLK36_12180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KLK36_12210	COG1115	amino acid carrier protein
KLK36_12215	COG1584	GPR1 FUN34 yaaH family protein
KLK36_12225	COG0351	phosphomethylpyrimidine kinase
KLK36_12230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KLK36_12230	COG0519	Catalyzes the synthesis of GMP from XMP
KLK36_12235	COG0516	GMP reductase activity
KLK36_12235	COG0517	IMP dehydrogenase activity
KLK36_12250	COG1160	GTP binding
KLK36_12260	COG2976	Protein conserved in bacteria
KLK36_12275	COG1426	Protein conserved in bacteria
KLK36_12290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KLK36_12295	COG2975	iron-sulfur cluster assembly
KLK36_12300	COG0633	Ferredoxin
KLK36_12315	COG0316	Belongs to the HesB IscA family
KLK36_12320	COG0822	iron-sulfur transferase activity
KLK36_12330	COG1959	2 iron, 2 sulfur cluster binding
KLK36_12335	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KLK36_12340	COG0483	inositol monophosphate 1-phosphatase activity
KLK36_12345	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KLK36_12350	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KLK36_12355	COG1862	Preprotein translocase
KLK36_12360	COG0343	queuine tRNA-ribosyltransferase activity
KLK36_12370	COG0517	IMP dehydrogenase activity
KLK36_12380	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KLK36_12385	COG0583	DNA-binding transcription factor activity
KLK36_12390	COG0450	alkyl hydroperoxide reductase
KLK36_12400	COG0704	Plays a role in the regulation of phosphate uptake
KLK36_12405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KLK36_12410	COG0581	inorganic phosphate transmembrane transporter activity
KLK36_12420	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KLK36_12440	COG0745	RESPONSE REGULATOR receiver
KLK36_12450	COG0826	peptidase U32
KLK36_12455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KLK36_12495	COG0542	response to heat
KLK36_12500	COG1496	oxidoreductase activity
KLK36_12505	COG0564	pseudouridine synthase activity
KLK36_12520	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KLK36_12525	COG1605	Chorismate mutase
KLK36_12525	COG0077	Prephenate dehydratase
KLK36_12530	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KLK36_12535	COG5001	Diguanylate cyclase
KLK36_12540	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KLK36_12545	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
KLK36_12555	COG0488	(ABC) transporter
KLK36_12565	COG1605	Chorismate mutase
KLK36_12565	COG0287	Prephenate dehydrogenase
KLK36_12570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KLK36_12575	COG3275	phosphorelay sensor kinase activity
KLK36_12590	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KLK36_12595	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KLK36_12610	COG1966	Carbon starvation protein
KLK36_12615	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KLK36_12620	COG1047	Peptidyl-prolyl cis-trans
KLK36_12625	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KLK36_12640	COG0728	peptidoglycan biosynthetic process
KLK36_12645	COG0268	Binds directly to 16S ribosomal RNA
KLK36_12650	COG0640	Transcriptional regulator
KLK36_12660	COG1283	sodium-dependent phosphate transmembrane transporter activity
KLK36_12670	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KLK36_12695	COG2433	Pfam Transposase IS66
KLK36_12730	COG3550	peptidyl-serine autophosphorylation
KLK36_12745	COG3422	double-strand break repair
KLK36_12765	COG2433	Pfam Transposase IS66
KLK36_12775	COG2194	sulfuric ester hydrolase activity
KLK36_12780	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KLK36_12805	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KLK36_12815	COG0730	response to heat
KLK36_12825	COG0494	nUDIX hydrolase
KLK36_12835	COG0667	Aldo Keto reductase
KLK36_12850	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KLK36_12865	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KLK36_12870	COG0513	Belongs to the DEAD box helicase family
KLK36_12895	COG3153	acetyltransferase
KLK36_12900	COG3154	lipid carrier protein
KLK36_12910	COG0826	peptidase U32
KLK36_12915	COG0826	peptidase U32
KLK36_12925	COG1846	Transcriptional regulator
KLK36_12940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KLK36_12960	COG0195	Participates in both transcription termination and antitermination
KLK36_12965	COG0779	Required for maturation of 30S ribosomal subunits
KLK36_12980	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KLK36_12985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KLK36_12990	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KLK36_12995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLK36_13000	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KLK36_13005	COG1534	Rna-binding protein
KLK36_13010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KLK36_13020	COG2027	D-alanyl-D-alanine carboxypeptidase
KLK36_13025	COG2239	Acts as a magnesium transporter
KLK36_13030	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KLK36_13035	COG0739	heme binding
KLK36_13050	COG0316	Belongs to the HesB IscA family
KLK36_13055	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KLK36_13060	COG0628	permease
KLK36_13070	COG2205	protein histidine kinase activity
KLK36_13070	COG0784	Response regulator, receiver
KLK36_13085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLK36_13090	COG0444	Belongs to the ABC transporter superfamily
KLK36_13095	COG4608	Belongs to the ABC transporter superfamily
KLK36_13105	COG2971	BadF BadG BcrA BcrD
KLK36_13120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KLK36_13135	COG1840	ABC-type Fe3 transport system, periplasmic component
KLK36_13140	COG0004	ammonium transporteR
KLK36_13150	COG3112	Uncharacterised protein family (UPF0231)
KLK36_13155	COG3835	regulator
KLK36_13165	COG1929	Belongs to the glycerate kinase type-1 family
KLK36_13180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KLK36_13185	COG1643	Atp-dependent helicase
KLK36_13190	COG1489	DNA binding
KLK36_13195	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KLK36_13200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KLK36_13210	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KLK36_13220	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KLK36_13230	COG0842	Transport permease protein
KLK36_13235	COG1131	(ABC) transporter
KLK36_13240	COG0659	secondary active sulfate transmembrane transporter activity
KLK36_13245	COG0288	reversible hydration of carbon dioxide
KLK36_13260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KLK36_13265	COG0508	dehydrogenase complex catalyzes the overall conversion of
KLK36_13270	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KLK36_13275	COG2186	Transcriptional regulator
KLK36_13280	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KLK36_13285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KLK36_13290	COG4974	Belongs to the 'phage' integrase family
KLK36_13295	COG0716	FMN binding
KLK36_13315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KLK36_13320	COG1459	type II secretion system
KLK36_13330	COG0237	dephospho-CoA kinase activity
KLK36_13335	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KLK36_13345	COG0335	large ribosomal subunit rRNA binding
KLK36_13350	COG0336	Belongs to the RNA methyltransferase TrmD family
KLK36_13355	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KLK36_13360	COG0228	four-way junction DNA binding
KLK36_13380	COG1854	S-ribosylhomocysteine lyase activity
KLK36_13390	COG0612	Peptidase, M16
KLK36_13405	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KLK36_13410	COG0511	ligase activity, forming carbon-carbon bonds
KLK36_13410	COG5016	pyruvate
KLK36_13415	COG3630	sodium ion export across plasma membrane
KLK36_13455	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KLK36_13460	COG0527	aspartate kinase activity
KLK36_13465	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KLK36_13475	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KLK36_13480	COG1546	Belongs to the CinA family
KLK36_13485	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KLK36_13490	COG4208	sulfate ABC transporter
KLK36_13510	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KLK36_13515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KLK36_13525	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KLK36_13530	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KLK36_13540	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KLK36_13550	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KLK36_13555	COG1968	undecaprenyl-diphosphatase activity
KLK36_13560	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KLK36_13565	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KLK36_13585	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KLK36_13590	COG1610	YqeY-like protein
KLK36_13635	COG0210	DNA helicase
KLK36_13765	COG4584	PFAM Integrase catalytic
KLK36_13770	COG1484	DNA-dependent DNA replication
KLK36_13900	COG4104	PAAR repeat-containing protein
KLK36_13925	COG4932	domain protein
KLK36_13925	COG5492	domain, Protein
KLK36_13935	COG1349	DNA-binding transcription factor activity
KLK36_13965	COG0668	transmembrane transport
KLK36_13970	COG0191	fructose-bisphosphate aldolase activity
KLK36_13975	COG0126	phosphoglycerate kinase activity
KLK36_13980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KLK36_13985	COG4771	TonB-dependent receptor
KLK36_13990	COG0583	DNA-binding transcription factor activity
KLK36_13995	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KLK36_14000	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KLK36_14005	COG3091	SprT-like family
KLK36_14010	COG2356	endonuclease I
KLK36_14015	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KLK36_14025	COG1678	Uncharacterized ACR, COG1678
KLK36_14030	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KLK36_14045	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KLK36_14050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KLK36_14055	COG0762	integral membrane protein
KLK36_14060	COG1872	DUF167
KLK36_14070	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KLK36_14075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KLK36_14080	COG2066	Belongs to the glutaminase family
KLK36_14095	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KLK36_14100	COG0741	lytic transglycosylase activity
KLK36_14150	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KLK36_14155	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KLK36_14160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KLK36_14165	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KLK36_14170	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KLK36_14175	COG2967	ApaG domain
KLK36_14190	COG3610	response to peptide
KLK36_14195	COG2966	Psort location CytoplasmicMembrane, score
KLK36_14200	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KLK36_14205	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KLK36_14210	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KLK36_14220	COG0531	amino acid
KLK36_14230	COG1438	arginine binding
KLK36_14235	COG2358	TRAP transporter, solute receptor (TAXI family
KLK36_14245	COG0589	response to stress
KLK36_14265	COG2235	arginine
KLK36_14270	COG0312	modulator of DNA gyrase
KLK36_14275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KLK36_14280	COG3164	Protein of unknown function
KLK36_14290	COG0424	maF-like protein
KLK36_14295	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KLK36_14300	COG1792	Involved in formation and maintenance of cell shape
KLK36_14305	COG1077	Cell shape determining protein MreB Mrl
KLK36_14340	COG2165	general secretion pathway protein
KLK36_14350	COG1459	type II secretion system
KLK36_14355	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KLK36_14365	COG3409	Peptidoglycan-binding domain 1 protein
KLK36_14365	COG3267	Type II secretory pathway component ExeA
KLK36_14390	COG2199	diguanylate cyclase activity
KLK36_14390	COG2200	EAL domain
KLK36_14395	COG0629	single-stranded DNA binding
KLK36_14410	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KLK36_14420	COG2239	Acts as a magnesium transporter
KLK36_14430	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KLK36_14435	COG0527	aspartate kinase activity
KLK36_14455	COG3344	reverse transcriptase
KLK36_14470	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KLK36_14475	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KLK36_14480	COG4604	ABC transporter, ATP-binding protein
KLK36_14485	COG4605	iron ion homeostasis
KLK36_14490	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KLK36_14495	COG4607	ABC-type enterochelin transport system periplasmic component
KLK36_14525	COG5380	lipid catabolic process
KLK36_14530	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KLK36_14555	COG0443	Heat shock 70 kDa protein
KLK36_14565	COG2814	Major facilitator Superfamily
KLK36_14575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KLK36_14575	COG4191	Histidine kinase
KLK36_14585	COG2207	Transcriptional regulator
KLK36_14590	COG0534	Mate efflux family protein
KLK36_14595	COG0840	transmembrane signaling receptor activity
KLK36_14600	COG2154	pterin-4-alpha-carbinolamine dehydratase
KLK36_14605	COG3186	Phenylalanine-4-hydroxylase
KLK36_14610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KLK36_14625	COG0583	DNA-binding transcription factor activity
KLK36_14640	COG0110	maltose O-acetyltransferase activity
KLK36_14645	COG1765	OsmC-like protein
KLK36_14650	COG0673	inositol 2-dehydrogenase activity
KLK36_14670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KLK36_14685	COG0784	Response regulator, receiver
KLK36_14685	COG2205	protein histidine kinase activity
KLK36_14685	COG5002	protein histidine kinase activity
KLK36_14695	COG1151	hydroxylamine reductase activity
KLK36_14710	COG0531	amino acid
KLK36_14720	COG3850	Histidine kinase
KLK36_14720	COG3437	response regulator, receiver
KLK36_14720	COG2205	protein histidine kinase activity
KLK36_14720	COG4999	Histidine kinase
KLK36_14725	COG3437	response regulator, receiver
KLK36_14735	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KLK36_14745	COG4251	negative regulation of phosphorylation
KLK36_14745	COG3706	GGDEF domain
KLK36_14745	COG2203	Gaf domain
KLK36_14745	COG5001	Diguanylate cyclase
KLK36_14750	COG3279	Response regulator of the LytR AlgR family
KLK36_14755	COG0745	RESPONSE REGULATOR receiver
KLK36_14755	COG2972	Histidine kinase
KLK36_14770	COG4591	ABC-type transport system involved in lipoprotein release permease component
KLK36_14775	COG0577	efflux transmembrane transporter activity
KLK36_14775	COG1136	(ABC) transporter
KLK36_14785	COG4989	oxidoreductase activity
KLK36_14790	COG0366	Alpha amylase catalytic
KLK36_14805	COG2267	carboxylic ester hydrolase activity
KLK36_14810	COG2188	Transcriptional regulator
KLK36_14820	COG1735	metal-dependent hydrolase with the TIM-barrel fold
KLK36_14835	COG3457	Alanine racemase
KLK36_14840	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KLK36_14870	COG0513	Belongs to the DEAD box helicase family
KLK36_14880	COG1388	LysM domain
KLK36_14880	COG1376	ErfK ybiS ycfS ynhG family protein
KLK36_14885	COG0415	Belongs to the DNA photolyase family
KLK36_14890	COG0789	Transcriptional regulator
KLK36_14895	COG3272	Protein of unknown function (DUF1722)
KLK36_14900	COG0813	purine-nucleoside phosphorylase activity
KLK36_14925	COG1566	PFAM secretion protein HlyD family protein
KLK36_14950	COG0786	glutamate:sodium symporter activity
KLK36_14965	COG1999	signal sequence binding
KLK36_14985	COG0366	Alpha amylase catalytic
KLK36_15045	COG0561	phosphatase activity
KLK36_15050	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KLK36_15075	COG1132	(ABC) transporter
KLK36_15085	COG0671	phosphoesterase, PA-phosphatase related
KLK36_15125	COG1131	(ABC) transporter
KLK36_15130	COG2188	Transcriptional regulator
KLK36_15140	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KLK36_15200	COG3501	Rhs element vgr protein
KLK36_15225	COG3829	transcription factor binding
KLK36_15290	COG0564	pseudouridine synthase activity
KLK36_15300	COG0745	RESPONSE REGULATOR receiver
KLK36_15315	COG1309	transcriptional regulator
KLK36_15320	COG2130	NADP-dependent
KLK36_15330	COG1328	CTP reductase activity
KLK36_15345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KLK36_15355	COG0513	Belongs to the DEAD box helicase family
KLK36_15375	COG1175	transmembrane transport
KLK36_15385	COG3842	ATPase activity
KLK36_15400	COG1131	(ABC) transporter
KLK36_15405	COG0842	Transport permease protein
KLK36_15410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KLK36_15415	COG3046	protein related to deoxyribodipyrimidine photolyase
KLK36_15420	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KLK36_15430	COG1846	Transcriptional regulator
KLK36_15455	COG2259	Doxx family
KLK36_15460	COG1301	dicarboxylic acid transport
KLK36_15475	COG3722	fumarate hydratase activity
KLK36_15480	COG0246	Mannitol dehydrogenase
KLK36_15485	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KLK36_15485	COG2213	PTS system mannitol-specific
KLK36_15490	COG0739	heme binding
KLK36_15500	COG0363	glucosamine-6-phosphate deaminase activity
KLK36_15520	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KLK36_15525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KLK36_15545	COG3304	Inner membrane component domain
KLK36_15555	COG2910	NAD(P)H-binding
KLK36_15560	COG0583	DNA-binding transcription factor activity
KLK36_15590	COG0814	amino acid
KLK36_15595	COG2084	Dehydrogenase
KLK36_15655	COG1444	tRNA N-acetyltransferase activity
KLK36_15665	COG0745	RESPONSE REGULATOR receiver
KLK36_15670	COG0643	Histidine kinase
KLK36_15670	COG2198	Histidine kinase
KLK36_15675	COG0835	chemotaxis
KLK36_15690	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KLK36_15695	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KLK36_15745	COG0259	pyridoxamine-phosphate oxidase activity
KLK36_15755	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KLK36_15815	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KLK36_15840	COG2909	trisaccharide binding
KLK36_15845	COG0058	SHG alpha-glucan phosphorylase activity
KLK36_15850	COG1640	4-alpha-glucanotransferase
KLK36_15865	COG3409	Peptidoglycan-binding domain 1 protein
KLK36_15865	COG3501	Rhs element vgr protein
KLK36_15875	COG1869	D-ribose catabolic process
KLK36_15885	COG1172	Belongs to the binding-protein-dependent transport system permease family
KLK36_15890	COG1879	ABC-type sugar transport system periplasmic component
KLK36_15895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KLK36_15900	COG1609	Transcriptional regulator
KLK36_15940	COG0363	glucosamine-6-phosphate deaminase activity
KLK36_15945	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KLK36_15955	COG1067	ATP-dependent peptidase activity
KLK36_15985	COG4580	involved in the transport of maltose and maltodextrins
KLK36_15990	COG1609	Transcriptional regulator
KLK36_16005	COG0395	ABC-type sugar transport system, permease component
KLK36_16010	COG3842	ATPase activity
KLK36_16020	COG1609	Transcriptional regulator
KLK36_16050	COG3122	Protein conserved in bacteria
KLK36_16055	COG1881	PFAM PEBP family protein
KLK36_16075	COG1620	l-lactate permease
KLK36_16080	COG0583	DNA-binding transcription factor activity
KLK36_16115	COG0584	glycerophosphoryl diester phosphodiesterase
KLK36_16120	COG2271	Major facilitator Superfamily
KLK36_16135	COG3047	cAMP biosynthetic process
KLK36_16160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KLK36_16165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KLK36_16180	COG0573	inorganic phosphate transmembrane transporter activity
KLK36_16185	COG0581	inorganic phosphate transmembrane transporter activity
KLK36_16190	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KLK36_16205	COG3314	Sporulation integral membrane protein YlbJ
KLK36_16210	COG0659	secondary active sulfate transmembrane transporter activity
KLK36_16220	COG0739	heme binding
KLK36_16225	COG5001	Diguanylate cyclase
KLK36_16230	COG0583	DNA-binding transcription factor activity
KLK36_16235	COG2814	Major facilitator Superfamily
KLK36_16260	COG0179	Fumarylacetoacetate (FAA) hydrolase
KLK36_16280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KLK36_16285	COG0765	amino acid transport
KLK36_16290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KLK36_16295	COG0765	amino acid transport
KLK36_16305	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KLK36_16315	COG3123	guanosine phosphorylase activity
KLK36_16325	COG1741	Belongs to the pirin family
KLK36_16335	COG5001	Diguanylate cyclase
KLK36_16370	COG3706	GGDEF domain
KLK36_16375	COG2315	Protein conserved in bacteria
KLK36_16380	COG0835	chemotaxis
KLK36_16380	COG0784	Response regulator, receiver
KLK36_16385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KLK36_16395	COG3842	ATPase activity
KLK36_16405	COG1175	transmembrane transport
KLK36_16410	COG3833	ABC-type maltose transport systems, permease component
KLK36_16435	COG1349	DNA-binding transcription factor activity
KLK36_16440	COG2199	diguanylate cyclase activity
KLK36_16490	COG4790	Type iii secretion
KLK36_16540	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KLK36_16545	COG2354	Protein conserved in bacteria
KLK36_16550	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KLK36_16555	COG0418	dihydroorotase activity
KLK36_16565	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KLK36_16570	COG2195	Cleaves the N-terminal amino acid of tripeptides
KLK36_16580	COG3604	Transcriptional regulator
KLK36_16590	COG4681	YaeQ
KLK36_16595	COG1278	Cold shock
KLK36_16620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLK36_16625	COG0516	GMP reductase activity
KLK36_16640	COG0589	response to stress
KLK36_16645	COG0659	secondary active sulfate transmembrane transporter activity
KLK36_16655	COG0798	PFAM Bile acid sodium symporter
KLK36_16660	COG0640	Transcriptional regulator
KLK36_16665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KLK36_16685	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KLK36_16690	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KLK36_16700	COG2271	Major facilitator Superfamily
KLK36_16705	COG3851	Histidine kinase
KLK36_16725	COG0346	lactoylglutathione lyase activity
KLK36_16735	COG0156	8-amino-7-oxononanoate synthase activity
KLK36_16740	COG1063	alcohol dehydrogenase
KLK36_16745	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KLK36_16755	COG1368	sulfuric ester hydrolase activity
KLK36_16760	COG3530	Putative quorum-sensing-regulated virulence factor
KLK36_16800	COG2304	oxidoreductase activity
KLK36_16820	COG0714	Associated with various cellular activities
KLK36_16840	COG0366	Alpha amylase catalytic
KLK36_16875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KLK36_16880	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KLK36_16890	COG0456	acetyltransferase
KLK36_16895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KLK36_16900	COG0662	Cupin 2, conserved barrel domain protein
KLK36_16905	COG0527	aspartate kinase activity
KLK36_16910	COG2239	Acts as a magnesium transporter
KLK36_16925	COG2113	Glycine betaine
KLK36_16930	COG4176	ABC-type proline glycine betaine transport system permease component
KLK36_16945	COG1166	arginine decarboxylase activity
KLK36_16950	COG0010	Belongs to the arginase family
KLK36_16970	COG5001	Diguanylate cyclase
KLK36_16970	COG3300	MHYT domain
KLK36_16975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KLK36_17015	COG0484	heat shock protein binding
KLK36_17025	COG1716	ATPase activity
KLK36_17025	COG5001	Diguanylate cyclase
KLK36_17030	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KLK36_17040	COG4181	ATPase activity
KLK36_17045	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KLK36_17055	COG1984	allophanate hydrolase subunit 2
KLK36_17065	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KLK36_17070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KLK36_17080	COG0814	amino acid
KLK36_17085	COG0513	Belongs to the DEAD box helicase family
KLK36_17095	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
KLK36_17110	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KLK36_17130	COG4176	ABC-type proline glycine betaine transport system permease component
KLK36_17160	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KLK36_17180	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KLK36_17200	COG3118	belongs to the thioredoxin family
KLK36_17205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KLK36_17210	COG0247	lactate metabolic process
KLK36_17220	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KLK36_17225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KLK36_17250	COG3132	Protein of unknown function, DUF480
KLK36_17255	COG2827	Endonuclease containing a URI domain
KLK36_17270	COG5002	protein histidine kinase activity
KLK36_17270	COG0784	Response regulator, receiver
KLK36_17300	COG1289	transmembrane transporter activity
KLK36_17305	COG0210	DNA helicase
KLK36_17310	COG1803	Methylglyoxal synthase
KLK36_17315	COG1879	ABC-type sugar transport system periplasmic component
KLK36_17320	COG2205	protein histidine kinase activity
KLK36_17320	COG0784	Response regulator, receiver
KLK36_17320	COG2198	Histidine kinase
KLK36_17325	COG0469	pyruvate kinase activity
KLK36_17330	COG2271	Major facilitator Superfamily
KLK36_17350	COG1979	alcohol dehydrogenase
KLK36_17365	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KLK36_17380	COG3111	PFAM Bacterial OB fold (BOF) protein
KLK36_17385	COG1492	cobalamin metabolic process
KLK36_17390	COG0725	ABC transporter, periplasmic molybdate-binding protein
KLK36_17395	COG4149	molybdate abc transporter
KLK36_17410	COG4251	negative regulation of phosphorylation
KLK36_17410	COG5001	Diguanylate cyclase
KLK36_17410	COG2203	Gaf domain
KLK36_17410	COG3706	GGDEF domain
KLK36_17425	COG3437	response regulator, receiver
KLK36_17445	COG5001	Diguanylate cyclase
KLK36_17445	COG3300	MHYT domain
KLK36_17580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KLK36_17585	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KLK36_17690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KLK36_17695	COG3344	reverse transcriptase
KLK36_17715	COG3550	peptidyl-serine autophosphorylation
KLK36_17720	COG0446	pyridine nucleotide-disulphide oxidoreductase
KLK36_17760	COG3706	GGDEF domain
KLK36_17765	COG1328	CTP reductase activity
KLK36_17775	COG0602	queuosine metabolic process
KLK36_17870	COG0210	DNA helicase
KLK36_17880	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KLK36_17920	COG2433	Pfam Transposase IS66
KLK36_17940	COG0602	queuosine metabolic process
KLK36_17950	COG0189	ligase activity
KLK36_17950	COG4067	protein conserved in archaea
KLK36_17965	COG4174	ABC transporter (Permease)
KLK36_17970	COG4239	(ABC) transporter, permease
KLK36_17975	COG4172	Belongs to the ABC transporter superfamily
KLK36_17990	COG3038	cytochrome b561
KLK36_17995	COG2353	YceI-like domain
KLK36_18000	COG0840	transmembrane signaling receptor activity
KLK36_18005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KLK36_18010	COG0545	Peptidyl-prolyl cis-trans isomerase
KLK36_18025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KLK36_18045	COG2897	thiosulfate sulfurtransferase activity
KLK36_18050	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KLK36_18055	COG0303	'Molybdopterin
KLK36_18060	COG0302	gtp cyclohydrolase
KLK36_18065	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KLK36_18065	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KLK36_18070	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KLK36_18080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLK36_18085	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KLK36_18090	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
KLK36_18095	COG1011	Hydrolase
KLK36_18100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KLK36_18105	COG2188	Transcriptional regulator
KLK36_18115	COG3104	oligopeptide transport
KLK36_18125	COG2116	formate transmembrane transporter activity
KLK36_18130	COG0583	DNA-binding transcription factor activity
KLK36_18140	COG3593	DNA synthesis involved in DNA repair
KLK36_18145	COG0737	Belongs to the 5'-nucleotidase family
KLK36_18155	COG2433	Pfam Transposase IS66
KLK36_18175	COG0500	methyltransferase
KLK36_18310	COG2433	Pfam Transposase IS66
KLK36_18390	COG2433	Pfam Transposase IS66
KLK36_18410	COG2433	Pfam Transposase IS66
KLK36_18435	COG2824	Alkylphosphonate utilization operon protein PhnA
KLK36_18445	COG2050	protein possibly involved in aromatic compounds catabolism
KLK36_18460	COG0488	(ABC) transporter
KLK36_18465	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KLK36_18480	COG0625	glutathione transferase activity
KLK36_18485	COG2501	S4 domain
KLK36_18500	COG0840	transmembrane signaling receptor activity
KLK36_18510	COG1278	Cold shock
KLK36_18515	COG3706	GGDEF domain
KLK36_18530	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KLK36_18535	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KLK36_18545	COG0745	RESPONSE REGULATOR receiver
KLK36_18560	COG3140	Belongs to the UPF0181 family
KLK36_18575	COG2433	Pfam Transposase IS66
KLK36_18590	COG0583	DNA-binding transcription factor activity
KLK36_18605	COG1181	Belongs to the D-alanine--D-alanine ligase family
KLK36_18620	COG0023	Translation Initiation Factor
KLK36_18850	COG0724	RNA recognition motif
KLK36_18880	COG2433	Pfam Transposase IS66
KLK36_18945	COG3040	lipid binding
KLK36_19085	COG2433	Pfam Transposase IS66
KLK36_19100	COG2433	Pfam Transposase IS66
KLK36_19130	COG2433	Pfam Transposase IS66
KLK36_19160	COG0513	Belongs to the DEAD box helicase family
KLK36_19165	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
KLK36_19175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KLK36_19215	COG0270	DNA (cytosine-5-)-methyltransferase activity
KLK36_19275	COG1742	UPF0060 membrane protein
KLK36_19300	COG2433	Pfam Transposase IS66
KLK36_19320	COG1484	DNA-dependent DNA replication
KLK36_19340	COG3069	C4-dicarboxylate transmembrane transporter activity
KLK36_19345	COG2197	response regulator
KLK36_19355	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KLK36_19365	COG0243	molybdopterin cofactor binding
KLK36_19375	COG3005	denitrification pathway
KLK36_19385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KLK36_19390	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KLK36_19415	COG3833	ABC-type maltose transport systems, permease component
KLK36_19420	COG1175	transmembrane transport
KLK36_19425	COG2182	Extracellular solute-binding protein
KLK36_19435	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KLK36_19445	COG3842	ATPase activity
KLK36_19460	COG3730	PTS system glucitol sorbitol-specific
KLK36_19465	COG1349	DNA-binding transcription factor activity
KLK36_19470	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
KLK36_19475	COG1028	Short-chain dehydrogenase reductase Sdr
KLK36_19490	COG3730	PTS system glucitol sorbitol-specific
KLK36_19510	COG3675	Pfam Lipase (class 3)
KLK36_19520	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KLK36_19535	COG1136	(ABC) transporter
KLK36_19535	COG0577	efflux transmembrane transporter activity
KLK36_19545	COG1136	(ABC) transporter
KLK36_19550	COG0523	cobalamin synthesis protein
KLK36_19565	COG0156	8-amino-7-oxononanoate synthase activity
KLK36_19570	COG2205	protein histidine kinase activity
KLK36_19570	COG0784	Response regulator, receiver
KLK36_19575	COG0419	ATPase involved in DNA repair
KLK36_19580	COG0420	3'-5' exonuclease activity
KLK36_19585	COG1609	Transcriptional regulator
KLK36_19590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KLK36_19590	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KLK36_19595	COG1105	Belongs to the carbohydrate kinase PfkB family
KLK36_19615	COG0612	Peptidase, M16
KLK36_19635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KLK36_19645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KLK36_19650	COG0509	glycine decarboxylation via glycine cleavage system
KLK36_19695	COG0656	L-ascorbic acid biosynthetic process
KLK36_19700	COG2249	NAD(P)H dehydrogenase (quinone) activity
KLK36_19710	COG0861	Integral membrane protein TerC family
KLK36_19720	COG2226	methyltransferase
KLK36_19730	COG1162	GTPase activity
KLK36_19735	COG2433	Pfam Transposase IS66
KLK36_19765	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KLK36_19770	COG4605	iron ion homeostasis
KLK36_19775	COG4607	ABC-type enterochelin transport system periplasmic component
KLK36_19865	COG3657	addiction module killer protein
KLK36_19890	COG1192	Involved in chromosome partitioning
KLK36_19950	COG4604	ABC transporter, ATP-binding protein
KLK36_19955	COG1535	isochorismatase
KLK36_19955	COG3433	isochorismatase activity
KLK36_19960	COG1021	2,3-dihydroxybenzoate-AMP ligase
KLK36_19965	COG1169	isochorismate synthase
KLK36_19980	COG2433	Pfam Transposase IS66
KLK36_20050	COG1028	Short-chain dehydrogenase reductase Sdr
KLK36_20165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KLK36_20295	COG3077	Addiction module antitoxin, RelB DinJ family
KLK36_20300	COG3041	Addiction module toxin RelE StbE family
KLK36_20335	COG0697	spore germination
KLK36_20360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KLK36_20395	COG0789	Transcriptional regulator
KLK36_20405	COG2608	mercury ion transmembrane transporter activity
KLK36_20410	COG2608	mercury ion transmembrane transporter activity
KLK36_20415	COG0789	Transcriptional regulator
KLK36_20435	COG4962	Type ii secretion system protein e
KLK36_20440	COG3838	Conjugal transfer protein Trbc
KLK36_20445	COG5268	conjugation