locus-tag	class	description
CEG15_00005	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEG15_00015	COG0706	membrane insertase activity
CEG15_00020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CEG15_00035	COG1126	abc transporter atp-binding protein
CEG15_00055	COG0592	DNA-directed DNA polymerase activity
CEG15_00060	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEG15_00065	COG0187	DNA topoisomerase II activity
CEG15_00080	COG0071	Belongs to the small heat shock protein (HSP20) family
CEG15_00085	COG3977	Valine--pyruvate aminotransferase
CEG15_00095	COG0752	glycyl-tRNA synthetase alpha subunit
CEG15_00100	COG2119	membrane
CEG15_00125	COG0604	alcohol dehydrogenase
CEG15_00135	COG0129	dihydroxy-acid dehydratase activity
CEG15_00140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEG15_00145	COG3978	acetolactate synthase activity
CEG15_00155	COG0606	chelatase, subunit chli
CEG15_00165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEG15_00170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CEG15_00185	COG3084	Protein conserved in bacteria
CEG15_00195	COG1272	protein, Hemolysin III
CEG15_00205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEG15_00210	COG0569	domain protein
CEG15_00215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEG15_00215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEG15_00220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEG15_00225	COG0242	peptide deformylase activity
CEG15_00230	COG1652	LysM domain
CEG15_00235	COG0758	DNA mediated transformation
CEG15_00240	COG2922	Belongs to the Smg family
CEG15_00245	COG0551	DNA topoisomerase type I activity
CEG15_00255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CEG15_00260	COG0009	L-threonylcarbamoyladenylate synthase
CEG15_00265	COG0408	coproporphyrinogen oxidase activity
CEG15_00270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CEG15_00280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CEG15_00315	COG3071	HemY protein
CEG15_00320	COG2959	enzyme of heme biosynthesis
CEG15_00325	COG1587	Uroporphyrinogen-III synthase
CEG15_00335	COG3072	Adenylate cyclase
CEG15_00350	COG0019	diaminopimelate decarboxylase activity
CEG15_00365	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CEG15_00370	COG1011	Hydrolase
CEG15_00385	COG0561	phosphatase activity
CEG15_00390	COG2267	carboxylic ester hydrolase activity
CEG15_00395	COG1280	lysine exporter protein (LysE YggA)
CEG15_00400	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CEG15_00405	COG0783	Belongs to the Dps family
CEG15_00430	COG1943	Transposase
CEG15_00445	COG2095	MarC family integral membrane protein
CEG15_00455	COG0742	ribosomal rna small subunit methyltransferase
CEG15_00460	COG0552	protein localization to endoplasmic reticulum
CEG15_00465	COG2884	Cell division ATP-binding protein ftsE
CEG15_00470	COG2177	Part of the ABC transporter FtsEX involved in
CEG15_00475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEG15_00485	COG0705	Rhomboid family
CEG15_00490	COG1580	Controls the rotational direction of flagella during chemotaxis
CEG15_00495	COG3161	chorismate lyase activity
CEG15_00505	COG2937	Belongs to the GPAT DAPAT family
CEG15_00520	COG0534	Mate efflux family protein
CEG15_00540	COG3250	beta-galactosidase activity
CEG15_00570	COG0732	type I restriction modification DNA specificity domain
CEG15_00590	COG2003	Belongs to the UPF0758 family
CEG15_00640	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CEG15_00715	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CEG15_00720	COG3300	MHYT domain
CEG15_00720	COG5001	Diguanylate cyclase
CEG15_00730	COG3852	Histidine kinase
CEG15_00740	COG0174	glutamine synthetase
CEG15_00755	COG1490	D-aminoacyl-tRNA deacylase activity
CEG15_00760	COG0456	acetyltransferase
CEG15_00770	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CEG15_00775	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CEG15_00780	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CEG15_00785	COG3031	protein transport across the cell outer membrane
CEG15_00795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEG15_00800	COG1459	type II secretion system
CEG15_00805	COG2165	general secretion pathway protein
CEG15_00810	COG2165	general secretion pathway protein
CEG15_00815	COG2165	general secretion pathway protein
CEG15_00820	COG4795	General secretion pathway protein
CEG15_00825	COG3156	type II secretion system protein K
CEG15_00830	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CEG15_00835	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CEG15_00845	COG1218	3'(2'),5'-bisphosphate nucleotidase
CEG15_00850	COG0494	nUDIX hydrolase
CEG15_00855	COG0316	Belongs to the HesB IscA family
CEG15_00855	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CEG15_00860	COG1040	competence protein
CEG15_00865	COG0596	Alpha beta hydrolase
CEG15_00875	COG2183	response to ionizing radiation
CEG15_00880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEG15_00900	COG0583	DNA-binding transcription factor activity
CEG15_00910	COG0778	Nitroreductase
CEG15_00920	COG0745	RESPONSE REGULATOR receiver
CEG15_00930	COG2233	PERMEase
CEG15_00935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CEG15_00940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEG15_00945	COG1758	RNA polymerase activity
CEG15_00950	COG0194	GDP metabolic process
CEG15_00955	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CEG15_00960	COG0248	Ppx GppA phosphatase
CEG15_00970	COG3118	belongs to the thioredoxin family
CEG15_00975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CEG15_00985	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CEG15_01040	COG1943	Transposase
CEG15_01045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEG15_01055	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEG15_01060	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CEG15_01060	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CEG15_01065	COG1072	(Pantothenic acid kinase))
CEG15_01090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEG15_01095	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEG15_01100	COG0250	Participates in transcription elongation, termination and antitermination
CEG15_01110	COG0081	regulation of translation
CEG15_01115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CEG15_01120	COG0222	ribosome binding
CEG15_01125	COG0085	RNA polymerase activity
CEG15_01130	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CEG15_01135	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CEG15_01140	COG2816	NAD+ diphosphatase activity
CEG15_01160	COG4942	peptidase
CEG15_01165	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CEG15_01180	COG0490	domain, Protein
CEG15_01180	COG0471	metal ion transport
CEG15_01190	COG1162	GTPase activity
CEG15_01195	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CEG15_01240	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CEG15_01245	COG0802	atpase or kinase
CEG15_01255	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CEG15_01260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CEG15_01265	COG1923	regulation of RNA biosynthetic process
CEG15_01270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEG15_01275	COG0330	HflC and HflK could
CEG15_01280	COG0330	HflC and HflK could
CEG15_01285	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CEG15_01300	COG0545	Peptidyl-prolyl cis-trans isomerase
CEG15_01305	COG2964	Protein conserved in bacteria
CEG15_01310	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CEG15_01315	COG2923	Belongs to the DsrF TusC family
CEG15_01330	COG0049	tRNA binding
CEG15_01335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEG15_01340	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEG15_01345	COG0360	Binds together with S18 to 16S ribosomal RNA
CEG15_01350	COG2965	DNA replication, synthesis of RNA primer
CEG15_01360	COG0359	binds to the 23S rRNA
CEG15_01370	COG0305	Participates in initiation and elongation during chromosome replication
CEG15_01375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEG15_01380	COG0166	Belongs to the GPI family
CEG15_01390	COG0735	belongs to the Fur family
CEG15_01395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEG15_01415	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEG15_01425	COG0175	sulfate reduction
CEG15_01510	COG1410	methionine synthase
CEG15_01510	COG0646	methionine synthase
CEG15_01515	COG0527	aspartate kinase activity
CEG15_01520	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CEG15_01535	COG2239	Acts as a magnesium transporter
CEG15_01545	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEG15_01560	COG0629	single-stranded DNA binding
CEG15_01565	COG2200	EAL domain
CEG15_01565	COG2199	diguanylate cyclase activity
CEG15_01590	COG3267	Type II secretory pathway component ExeA
CEG15_01590	COG3409	Peptidoglycan-binding domain 1 protein
CEG15_01600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEG15_01605	COG1459	type II secretion system
CEG15_01650	COG1077	Cell shape determining protein MreB Mrl
CEG15_01655	COG1792	Involved in formation and maintenance of cell shape
CEG15_01660	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CEG15_01665	COG0424	maF-like protein
CEG15_01670	COG1530	ribonuclease E activity
CEG15_01675	COG3164	Protein of unknown function
CEG15_01680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEG15_01685	COG0312	modulator of DNA gyrase
CEG15_01690	COG2235	arginine
CEG15_01710	COG0589	response to stress
CEG15_01740	COG0531	amino acid
CEG15_01745	COG0142	geranyltranstransferase activity
CEG15_01760	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CEG15_01765	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEG15_01770	COG2966	Psort location CytoplasmicMembrane, score
CEG15_01775	COG3610	response to peptide
CEG15_01790	COG2967	ApaG domain
CEG15_01800	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CEG15_01805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEG15_01810	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CEG15_01815	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CEG15_01865	COG0741	lytic transglycosylase activity
CEG15_01905	COG2313	pseudouridylate synthase activity
CEG15_01915	COG1846	Transcriptional regulator
CEG15_01920	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEG15_01925	COG0697	spore germination
CEG15_01935	COG1942	4-Oxalocrotonate Tautomerase
CEG15_01940	COG0546	phosphoglycolate phosphatase activity
CEG15_01950	COG1194	a g-specific adenine glycosylase
CEG15_01955	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CEG15_01960	COG2066	Belongs to the glutaminase family
CEG15_01965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEG15_01980	COG1872	DUF167
CEG15_01985	COG0762	integral membrane protein
CEG15_01990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CEG15_01995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CEG15_02015	COG1678	Uncharacterized ACR, COG1678
CEG15_02025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEG15_02030	COG2356	endonuclease I
CEG15_02035	COG3091	SprT-like family
CEG15_02040	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CEG15_02045	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEG15_02050	COG0583	DNA-binding transcription factor activity
CEG15_02055	COG4771	TonB-dependent receptor
CEG15_02060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEG15_02065	COG0126	phosphoglycerate kinase activity
CEG15_02075	COG0191	fructose-bisphosphate aldolase activity
CEG15_02080	COG0668	transmembrane transport
CEG15_02100	COG3706	GGDEF domain
CEG15_02110	COG0469	pyruvate kinase activity
CEG15_02115	COG1349	DNA-binding transcription factor activity
CEG15_02140	COG3501	Rhs element vgr protein
CEG15_02180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEG15_02185	COG0358	DNA primase activity
CEG15_02190	COG1610	YqeY-like protein
CEG15_02210	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CEG15_02215	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CEG15_02220	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEG15_02225	COG1968	undecaprenyl-diphosphatase activity
CEG15_02230	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CEG15_02235	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CEG15_02240	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CEG15_02245	COG0585	pseudouridine synthase activity
CEG15_02250	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CEG15_02255	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CEG15_02260	COG1388	LysM domain
CEG15_02260	COG4942	peptidase
CEG15_02265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEG15_02270	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEG15_02290	COG4208	sulfate ABC transporter
CEG15_02295	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CEG15_02300	COG1546	Belongs to the CinA family
CEG15_02305	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CEG15_02310	COG2137	regulation of response to DNA damage stimulus
CEG15_02315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEG15_02320	COG0527	aspartate kinase activity
CEG15_02375	COG5016	pyruvate
CEG15_02375	COG0511	ligase activity, forming carbon-carbon bonds
CEG15_02380	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CEG15_02390	COG1238	metal cluster binding
CEG15_02395	COG0612	Peptidase, M16
CEG15_02410	COG4536	flavin adenine dinucleotide binding
CEG15_02415	COG4137	Cytochrome C assembly protein
CEG15_02420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEG15_02440	COG0335	large ribosomal subunit rRNA binding
CEG15_02445	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CEG15_02450	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CEG15_02455	COG0237	dephospho-CoA kinase activity
CEG15_02465	COG1459	type II secretion system
CEG15_02470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEG15_02480	COG0157	Belongs to the NadC ModD family
CEG15_02490	COG0716	FMN binding
CEG15_02495	COG4974	Belongs to the 'phage' integrase family
CEG15_02500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEG15_02505	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CEG15_02510	COG2186	Transcriptional regulator
CEG15_02515	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CEG15_02520	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEG15_02525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEG15_02540	COG0288	reversible hydration of carbon dioxide
CEG15_02545	COG0659	secondary active sulfate transmembrane transporter activity
CEG15_02550	COG1131	(ABC) transporter
CEG15_02555	COG0842	Transport permease protein
CEG15_02570	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CEG15_02580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEG15_02590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEG15_02595	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CEG15_02600	COG1489	DNA binding
CEG15_02605	COG1643	Atp-dependent helicase
CEG15_02610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEG15_02615	COG1752	Esterase of the alpha-beta hydrolase superfamily
CEG15_02620	COG1049	propionate catabolic process, 2-methylcitrate cycle
CEG15_02625	COG1929	Belongs to the glycerate kinase type-1 family
CEG15_02630	COG2610	gluconate transmembrane transporter activity
CEG15_02635	COG3835	regulator
CEG15_02650	COG0004	ammonium transporteR
CEG15_02655	COG1840	ABC-type Fe3 transport system, periplasmic component
CEG15_02665	COG3842	ATPase activity
CEG15_02670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEG15_02685	COG2971	BadF BadG BcrA BcrD
CEG15_02695	COG4608	Belongs to the ABC transporter superfamily
CEG15_02700	COG0444	Belongs to the ABC transporter superfamily
CEG15_02705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEG15_02730	COG0628	permease
CEG15_02735	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEG15_02740	COG0316	Belongs to the HesB IscA family
CEG15_02755	COG0739	heme binding
CEG15_02760	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CEG15_02770	COG2239	Acts as a magnesium transporter
CEG15_02775	COG2027	D-alanyl-D-alanine carboxypeptidase
CEG15_02785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEG15_02790	COG1534	Rna-binding protein
CEG15_02800	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEG15_02805	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CEG15_02810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEG15_02815	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEG15_02830	COG0779	Required for maturation of 30S ribosomal subunits
CEG15_02835	COG0195	Participates in both transcription termination and antitermination
CEG15_02850	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CEG15_02870	COG1846	Transcriptional regulator
CEG15_02900	COG3153	acetyltransferase
CEG15_02925	COG0513	Belongs to the DEAD box helicase family
CEG15_02945	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CEG15_02950	COG2204	response regulator
CEG15_02960	COG0667	Aldo Keto reductase
CEG15_02965	COG3066	DNA modification
CEG15_02970	COG0494	nUDIX hydrolase
CEG15_02975	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CEG15_02980	COG0730	response to heat
CEG15_02990	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEG15_03015	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEG15_03050	COG1132	(ABC) transporter
CEG15_03085	COG1283	sodium-dependent phosphate transmembrane transporter activity
CEG15_03090	COG0583	DNA-binding transcription factor activity
CEG15_03095	COG0640	Transcriptional regulator
CEG15_03105	COG0728	peptidoglycan biosynthetic process
CEG15_03110	COG0196	riboflavin kinase activity
CEG15_03120	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CEG15_03125	COG1047	Peptidyl-prolyl cis-trans
CEG15_03135	COG1966	Carbon starvation protein
CEG15_03145	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEG15_03150	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CEG15_03155	COG1472	Belongs to the glycosyl hydrolase 3 family
CEG15_03160	COG3279	Response regulator of the LytR AlgR family
CEG15_03165	COG3275	phosphorelay sensor kinase activity
CEG15_03170	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEG15_03175	COG1605	Chorismate mutase
CEG15_03175	COG0287	Prephenate dehydrogenase
CEG15_03185	COG0488	(ABC) transporter
CEG15_03200	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CEG15_03205	COG5001	Diguanylate cyclase
CEG15_03210	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEG15_03215	COG0077	Prephenate dehydratase
CEG15_03215	COG1605	Chorismate mutase
CEG15_03220	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEG15_03225	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEG15_03230	COG0564	pseudouridine synthase activity
CEG15_03240	COG0542	response to heat
CEG15_03285	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEG15_03300	COG0745	RESPONSE REGULATOR receiver
CEG15_03305	COG5002	protein histidine kinase activity
CEG15_03315	COG0248	Ppx GppA phosphatase
CEG15_03320	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CEG15_03330	COG0581	inorganic phosphate transmembrane transporter activity
CEG15_03335	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEG15_03340	COG0704	Plays a role in the regulation of phosphate uptake
CEG15_03345	COG3142	Participates in the control of copper homeostasis
CEG15_03350	COG0450	alkyl hydroperoxide reductase
CEG15_03355	COG0583	DNA-binding transcription factor activity
CEG15_03360	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CEG15_03370	COG0517	IMP dehydrogenase activity
CEG15_03375	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CEG15_03385	COG1862	Preprotein translocase
CEG15_03390	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEG15_03395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEG15_03400	COG0483	inositol monophosphate 1-phosphatase activity
CEG15_03405	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CEG15_03410	COG1959	2 iron, 2 sulfur cluster binding
CEG15_03420	COG0822	iron-sulfur transferase activity
CEG15_03425	COG0316	Belongs to the HesB IscA family
CEG15_03435	COG0443	Heat shock 70 kDa protein
CEG15_03440	COG0633	Ferredoxin
CEG15_03445	COG2975	iron-sulfur cluster assembly
CEG15_03450	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEG15_03470	COG1426	Protein conserved in bacteria
CEG15_03475	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CEG15_03480	COG0124	histidyl-tRNA synthetase
CEG15_03485	COG2976	Protein conserved in bacteria
CEG15_03490	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEG15_03495	COG1160	GTP binding
CEG15_03510	COG0517	IMP dehydrogenase activity
CEG15_03510	COG0516	GMP reductase activity
CEG15_03515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEG15_03515	COG0519	Catalyzes the synthesis of GMP from XMP
CEG15_03520	COG0351	phosphomethylpyrimidine kinase
CEG15_03530	COG1584	GPR1 FUN34 yaaH family protein
CEG15_03535	COG1115	amino acid carrier protein
CEG15_03540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEG15_03555	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CEG15_03560	COG3711	transcriptional antiterminator
CEG15_03560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_03575	COG3964	amidohydrolase
CEG15_03660	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CEG15_03665	COG4804	nuclease activity
CEG15_03670	COG0732	type I restriction modification DNA specificity domain
CEG15_03680	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CEG15_03700	COG2867	negative regulation of translational initiation
CEG15_03705	COG2914	Belongs to the UPF0125 (RnfH) family
CEG15_03710	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEG15_03715	COG0497	DNA recombination
CEG15_03725	COG0814	amino acid
CEG15_03735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEG15_03740	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEG15_03745	COG0443	Heat shock 70 kDa protein
CEG15_03750	COG0484	heat shock protein binding
CEG15_03780	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CEG15_03785	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CEG15_03795	COG0583	DNA-binding transcription factor activity
CEG15_03800	COG0590	tRNA wobble adenosine to inosine editing
CEG15_03805	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CEG15_03815	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEG15_03815	COG0047	phosphoribosylformylglycinamidine synthase activity
CEG15_03835	COG2979	Protein of unknown function (DUF533)
CEG15_03840	COG0442	prolyl-tRNA aminoacylation
CEG15_03845	COG1720	tRNA m6t6A37 methyltransferase activity
CEG15_03855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEG15_03885	COG3098	single-species biofilm formation
CEG15_03890	COG0564	pseudouridine synthase activity
CEG15_03895	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEG15_03900	COG0142	geranyltranstransferase activity
CEG15_03910	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CEG15_03920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEG15_03920	COG0301	tRNA thio-modification
CEG15_03925	COG0583	DNA-binding transcription factor activity
CEG15_03930	COG2363	Small membrane protein
CEG15_03940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEG15_03945	COG1611	Belongs to the LOG family
CEG15_03950	COG3706	GGDEF domain
CEG15_03970	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CEG15_03975	COG1464	Belongs to the NlpA lipoprotein family
CEG15_03980	COG2011	ABC-type metal ion transport system permease component
CEG15_03985	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEG15_03990	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CEG15_04005	COG1263	PTS System
CEG15_04005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEG15_04010	COG0366	Alpha amylase catalytic
CEG15_04015	COG0745	RESPONSE REGULATOR receiver
CEG15_04020	COG2205	protein histidine kinase activity
CEG15_04055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEG15_04060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEG15_04070	COG1943	Transposase
CEG15_04075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEG15_04080	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CEG15_04085	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CEG15_04125	COG1045	serine acetyltransferase
CEG15_04135	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CEG15_04165	COG0489	protein tyrosine kinase activity
CEG15_04170	COG1596	polysaccharide export
CEG15_04190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEG15_04205	COG0321	lipoyl(octanoyl) transferase activity
CEG15_04210	COG2921	Belongs to the UPF0250 family
CEG15_04215	COG1686	Belongs to the peptidase S11 family
CEG15_04220	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CEG15_04225	COG0772	Belongs to the SEDS family
CEG15_04230	COG0768	penicillin binding
CEG15_04235	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CEG15_04240	COG0799	negative regulation of ribosome biogenesis
CEG15_04245	COG1466	dna polymerase III delta subunit
CEG15_04250	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CEG15_04255	COG0495	leucyl-tRNA aminoacylation
CEG15_04260	COG2888	peptidyl-tyrosine sulfation
CEG15_04265	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CEG15_04270	COG4535	Mg2 and Co2 transporter CorC
CEG15_04280	COG1702	phosphate starvation-inducible protein PhoH
CEG15_04285	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEG15_04290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEG15_04295	COG2190	(PTS) system
CEG15_04300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEG15_04305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_04310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CEG15_04315	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CEG15_04320	COG3115	cell septum assembly
CEG15_04340	COG0789	Transcriptional regulator
CEG15_04350	COG0330	HflC and HflK could
CEG15_04355	COG3118	belongs to the thioredoxin family
CEG15_04360	COG1090	epimerase
CEG15_04365	COG0622	Phosphoesterase
CEG15_04380	COG3710	Transcriptional regulator
CEG15_04385	COG0326	Molecular chaperone. Has ATPase activity
CEG15_04395	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CEG15_04400	COG3104	oligopeptide transport
CEG15_04410	COG0367	asparagine synthase
CEG15_04415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEG15_04415	COG4651	solute:proton antiporter activity
CEG15_04420	COG1846	Transcriptional regulator
CEG15_04420	COG1940	carbohydrate kinase activity
CEG15_04425	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CEG15_04430	COG1263	PTS System
CEG15_04430	COG2190	(PTS) system
CEG15_04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEG15_04435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEG15_04455	COG0285	dihydrofolate synthase activity
CEG15_04460	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CEG15_04465	COG1286	toxin biosynthetic process
CEG15_04470	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CEG15_04475	COG2056	Na+-H+ antiporter family
CEG15_04480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEG15_04490	COG0346	lactoylglutathione lyase activity
CEG15_04495	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEG15_04510	COG4658	electron transport chain
CEG15_04515	COG4656	Part of a membrane complex involved in electron transport
CEG15_04520	COG2878	Part of a membrane complex involved in electron transport
CEG15_04525	COG4657	Part of a membrane complex involved in electron transport
CEG15_04535	COG1629	transport
CEG15_04535	COG4774	siderophore transport
CEG15_04540	COG2382	esterase
CEG15_04560	COG3433	isochorismatase activity
CEG15_04560	COG1535	isochorismatase
CEG15_04565	COG1021	2,3-dihydroxybenzoate-AMP ligase
CEG15_04570	COG1169	isochorismate synthase
CEG15_04575	COG1028	Short-chain dehydrogenase reductase Sdr
CEG15_04580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEG15_04585	COG1902	pentaerythritol trinitrate reductase activity
CEG15_04595	COG2814	Major facilitator Superfamily
CEG15_04600	COG1028	Short-chain dehydrogenase reductase Sdr
CEG15_04615	COG0556	nucleotide-excision repair
CEG15_04620	COG2204	response regulator
CEG15_04625	COG2198	Histidine kinase
CEG15_04630	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CEG15_04635	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CEG15_04640	COG0521	Mo-molybdopterin cofactor biosynthetic process
CEG15_04650	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CEG15_04655	COG0314	molybdopterin synthase activity
CEG15_04660	COG2199	diguanylate cyclase activity
CEG15_04665	COG4109	DRTGG domain
CEG15_04675	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CEG15_04685	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEG15_04685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEG15_04690	COG0489	protein tyrosine kinase activity
CEG15_04695	COG0572	uridine kinase
CEG15_04700	COG2982	Protein involved in outer membrane biogenesis
CEG15_04705	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CEG15_04710	COG2067	long-chain fatty acid transport protein
CEG15_04725	COG1595	DNA-templated transcription, initiation
CEG15_04735	COG0183	Belongs to the thiolase family
CEG15_04740	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEG15_04740	COG1024	Enoyl-CoA hydratase
CEG15_04745	COG0778	Nitroreductase
CEG15_04750	COG0583	DNA-binding transcription factor activity
CEG15_04755	COG0745	RESPONSE REGULATOR receiver
CEG15_04765	COG2832	Protein of unknown function (DUF454)
CEG15_04770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEG15_04780	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CEG15_04810	COG2226	methyltransferase
CEG15_04825	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEG15_04835	COG3139	Protein of unknown function (DUF1315)
CEG15_04840	COG0252	asparaginase activity
CEG15_04845	COG0616	signal peptide processing
CEG15_04850	COG1902	pentaerythritol trinitrate reductase activity
CEG15_04850	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEG15_04855	COG0788	formyltetrahydrofolate deformylase activity
CEG15_04865	COG1199	ATP-dependent helicase activity
CEG15_04870	COG1214	PFAM Peptidase M22, glycoprotease
CEG15_04885	COG0596	Alpha beta hydrolase
CEG15_04890	COG0318	PFAM AMP-dependent synthetase and ligase
CEG15_04895	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CEG15_04905	COG2894	cell division
CEG15_04915	COG3100	YcgL domain-containing protein
CEG15_04920	COG2951	lytic endotransglycosylase activity
CEG15_04925	COG0583	DNA-binding transcription factor activity
CEG15_04930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEG15_04955	COG4628	conserved protein (DUF2132)
CEG15_04970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEG15_04980	COG0513	Belongs to the DEAD box helicase family
CEG15_04990	COG1760	l-serine dehydratase
CEG15_04995	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CEG15_05000	COG0745	RESPONSE REGULATOR receiver
CEG15_05005	COG2205	protein histidine kinase activity
CEG15_05010	COG1653	transport
CEG15_05020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEG15_05025	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CEG15_05030	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEG15_05050	COG0544	peptidyl-prolyl cis-trans isomerase activity
CEG15_05065	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CEG15_05070	COG0776	regulation of translation
CEG15_05075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEG15_05080	COG1555	photosystem II stabilization
CEG15_05085	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CEG15_05090	COG0539	negative regulation of cytoplasmic translation
CEG15_05100	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CEG15_05105	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CEG15_05120	COG0583	DNA-binding transcription factor activity
CEG15_05130	COG0686	Belongs to the AlaDH PNT family
CEG15_05135	COG1522	sequence-specific DNA binding
CEG15_05150	COG0501	Belongs to the peptidase M48B family
CEG15_05160	COG0300	oxidoreductase activity
CEG15_05175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CEG15_05185	COG2268	Band 7 protein
CEG15_05195	COG1032	radical SAM domain protein
CEG15_05220	COG0583	DNA-binding transcription factor activity
CEG15_05225	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEG15_05235	COG2350	Protein conserved in bacteria
CEG15_05240	COG1607	acyl-coa hydrolase
CEG15_05270	COG0133	tryptophan synthase activity
CEG15_05275	COG0134	indole-3-glycerol-phosphate synthase activity
CEG15_05275	COG0135	phosphoribosylanthranilate isomerase activity
CEG15_05280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEG15_05285	COG0512	Glutamine amidotransferase of anthranilate synthase
CEG15_05290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CEG15_05300	COG0613	PHP domain protein
CEG15_05305	COG0009	L-threonylcarbamoyladenylate synthase
CEG15_05310	COG1187	pseudouridine synthase activity
CEG15_05320	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CEG15_05325	COG4988	ABC transporter
CEG15_05330	COG0492	ferredoxin-NADP+ reductase activity
CEG15_05335	COG0745	RESPONSE REGULATOR receiver
CEG15_05335	COG3706	GGDEF domain
CEG15_05350	COG2949	membrane
CEG15_05360	COG0281	malic enzyme
CEG15_05380	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CEG15_05390	COG1737	Transcriptional regulator
CEG15_05395	COG0076	glutamate decarboxylase activity
CEG15_05405	COG2431	L-lysine efflux transmembrane transporter activity
CEG15_05415	COG3070	regulator of competence-specific genes
CEG15_05430	COG4191	Histidine kinase
CEG15_05430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEG15_05440	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CEG15_05445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CEG15_05450	COG2915	High frequency lysogenization protein hflD homolog
CEG15_05455	COG0482	sulfurtransferase activity
CEG15_05465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEG15_05470	COG2916	Histone family protein nucleoid-structuring protein H-NS
CEG15_05475	COG1757	Na H antiporter
CEG15_05485	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEG15_05490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEG15_05495	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CEG15_05495	COG0131	Imidazoleglycerol-phosphate dehydratase
CEG15_05500	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CEG15_05510	COG0107	imidazoleglycerol-phosphate synthase activity
CEG15_05515	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CEG15_05515	COG0140	phosphoribosyl-ATP diphosphatase activity
CEG15_05520	COG1187	pseudouridine synthase activity
CEG15_05530	COG1278	Cold shock
CEG15_05535	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CEG15_05540	COG0542	response to heat
CEG15_05545	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CEG15_05550	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CEG15_05555	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CEG15_05560	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CEG15_05570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEG15_05575	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEG15_05580	COG0297	glycogen (starch) synthase activity
CEG15_05600	COG3070	regulator of competence-specific genes
CEG15_05605	COG1609	Transcriptional regulator
CEG15_05615	COG0745	RESPONSE REGULATOR receiver
CEG15_05620	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CEG15_05625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEG15_05635	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CEG15_05640	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CEG15_05655	COG4067	protein conserved in archaea
CEG15_05655	COG0189	ligase activity
CEG15_05660	COG0500	methyltransferase
CEG15_05670	COG1801	Protein of unknown function DUF72
CEG15_05675	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CEG15_05680	COG1435	thymidine kinase activity
CEG15_05690	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CEG15_05715	COG2116	formate transmembrane transporter activity
CEG15_05720	COG4459	periplasmic nitrate reductase
CEG15_05725	COG3005	denitrification pathway
CEG15_05730	COG0243	molybdopterin cofactor binding
CEG15_05740	COG1227	inorganic diphosphatase activity
CEG15_05760	COG3344	reverse transcriptase
CEG15_05770	COG4172	Belongs to the ABC transporter superfamily
CEG15_05780	COG4171	peptide transport system, permease
CEG15_05785	COG4168	peptide transport system, permease
CEG15_05795	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CEG15_05800	COG1842	Phage shock protein A
CEG15_05815	COG0519	Catalyzes the synthesis of GMP from XMP
CEG15_05820	COG0626	cystathionine gamma-synthase activity
CEG15_05830	COG0733	neurotransmitter:sodium symporter activity
CEG15_05835	COG0564	pseudouridine synthase activity
CEG15_05845	COG2200	EAL domain
CEG15_05850	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CEG15_05855	COG4136	ATPase activity
CEG15_05860	COG4135	transport system, permease component
CEG15_05865	COG4134	Bacterial extracellular solute-binding protein
CEG15_05875	COG3313	Fe-S protein
CEG15_05885	COG0737	Belongs to the 5'-nucleotidase family
CEG15_05895	COG0513	Belongs to the DEAD box helicase family
CEG15_05915	COG2205	protein histidine kinase activity
CEG15_05930	COG1061	Type III restriction enzyme res subunit
CEG15_05935	COG1187	pseudouridine synthase activity
CEG15_05940	COG2814	Major facilitator Superfamily
CEG15_05950	COG0702	epimerase
CEG15_05955	COG0534	Mate efflux family protein
CEG15_05960	COG4181	ATPase activity
CEG15_05975	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CEG15_05995	COG0019	diaminopimelate decarboxylase activity
CEG15_06030	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEG15_06035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEG15_06040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEG15_06050	COG0840	transmembrane signaling receptor activity
CEG15_06065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEG15_06065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEG15_06065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_06070	COG2207	Transcriptional regulator
CEG15_06080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEG15_06090	COG1342	Belongs to the UPF0251 family
CEG15_06110	COG1129	ABC transporter
CEG15_06120	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEG15_06125	COG5002	protein histidine kinase activity
CEG15_06130	COG0745	RESPONSE REGULATOR receiver
CEG15_06160	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CEG15_06165	COG0372	Belongs to the citrate synthase family
CEG15_06170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CEG15_06175	COG2828	Protein conserved in bacteria
CEG15_06195	COG0561	phosphatase activity
CEG15_06200	COG0602	queuosine metabolic process
CEG15_06245	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEG15_06250	COG1254	Belongs to the acylphosphatase family
CEG15_06255	COG2920	part of a sulfur-relay system
CEG15_06260	COG0670	Belongs to the BI1 family
CEG15_06265	COG1126	abc transporter atp-binding protein
CEG15_06270	COG0765	amino acid transport
CEG15_06275	COG4597	amino acid ABC transporter
CEG15_06280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEG15_06285	COG1648	precorrin-2 dehydrogenase activity
CEG15_06285	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEG15_06290	COG3706	GGDEF domain
CEG15_06290	COG0745	RESPONSE REGULATOR receiver
CEG15_06300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEG15_06305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEG15_06305	COG0574	Belongs to the PEP-utilizing enzyme family
CEG15_06320	COG2996	Protein conserved in bacteria
CEG15_06330	COG1943	Transposase
CEG15_06340	COG3008	intermembrane lipid transfer
CEG15_06345	COG2995	paraquat-inducible protein a
CEG15_06350	COG1132	(ABC) transporter
CEG15_06355	COG1956	GAF domain-containing protein
CEG15_06375	COG0308	aminopeptidase N
CEG15_06385	COG2902	Dehydrogenase
CEG15_06390	COG0167	dihydroorotate dehydrogenase activity
CEG15_06425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEG15_06430	COG1067	ATP-dependent peptidase activity
CEG15_06435	COG3120	sequence-specific DNA binding
CEG15_06530	COG3278	Belongs to the heme-copper respiratory oxidase family
CEG15_06545	COG2010	Cytochrome c
CEG15_06555	COG2217	Heavy metal translocating P-type atpase
CEG15_06570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEG15_06575	COG0589	response to stress
CEG15_06600	COG3842	ATPase activity
CEG15_06605	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEG15_06610	COG1177	transmembrane transport
CEG15_06615	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEG15_06620	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEG15_06625	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEG15_06630	COG0004	ammonium transporteR
CEG15_06635	COG0488	(ABC) transporter
CEG15_06640	COG2197	response regulator
CEG15_06650	COG2271	Major facilitator Superfamily
CEG15_06655	COG1840	ABC-type Fe3 transport system, periplasmic component
CEG15_06665	COG3842	ATPase activity
CEG15_06670	COG0746	molybdenum cofactor guanylyltransferase activity
CEG15_06675	COG1763	Mo-molybdopterin cofactor biosynthetic process
CEG15_06700	COG0840	transmembrane signaling receptor activity
CEG15_06705	COG0791	NLP P60 protein
CEG15_06730	COG1793	dna ligase
CEG15_06735	COG4667	esterase of the alpha-beta hydrolase superfamily
CEG15_06750	COG0848	biopolymer transport protein
CEG15_06755	COG0811	peptide transport
CEG15_06760	COG0811	peptide transport
CEG15_06790	COG0625	glutathione transferase activity
CEG15_06800	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CEG15_06810	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEG15_06825	COG1115	amino acid carrier protein
CEG15_06830	COG1280	lysine exporter protein (LysE YggA)
CEG15_06835	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CEG15_06840	COG0477	Major facilitator Superfamily
CEG15_06845	COG0583	DNA-binding transcription factor activity
CEG15_06855	COG1643	Atp-dependent helicase
CEG15_06875	COG3706	GGDEF domain
CEG15_06890	COG0443	Heat shock 70 kDa protein
CEG15_06920	COG1609	Transcriptional regulator
CEG15_06925	COG2723	6-phospho-beta-galactosidase activity
CEG15_06930	COG0513	Belongs to the DEAD box helicase family
CEG15_06935	COG0243	molybdopterin cofactor binding
CEG15_06940	COG3005	denitrification pathway
CEG15_06945	COG1278	Cold shock
CEG15_06960	COG4191	Histidine kinase
CEG15_06960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEG15_06965	COG0471	metal ion transport
CEG15_06975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEG15_06985	COG3706	GGDEF domain
CEG15_06995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEG15_07000	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CEG15_07005	COG3768	UPF0283 membrane protein
CEG15_07010	COG3106	COG3106 Predicted ATPase
CEG15_07030	COG0494	nUDIX hydrolase
CEG15_07035	COG0814	amino acid
CEG15_07040	COG1760	l-serine dehydratase
CEG15_07050	COG2356	endonuclease I
CEG15_07055	COG0720	synthase
CEG15_07060	COG0840	transmembrane signaling receptor activity
CEG15_07065	COG0017	Asparaginyl-tRNA synthetase
CEG15_07075	COG2201	protein-glutamate methylesterase activity
CEG15_07080	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CEG15_07085	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CEG15_07090	COG0835	chemotaxis
CEG15_07100	COG0643	Histidine kinase
CEG15_07100	COG2198	Histidine kinase
CEG15_07110	COG0745	RESPONSE REGULATOR receiver
CEG15_07120	COG3437	response regulator, receiver
CEG15_07120	COG2770	Histidine kinase
CEG15_07125	COG1448	Aminotransferase
CEG15_07130	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CEG15_07140	COG0840	transmembrane signaling receptor activity
CEG15_07145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEG15_07150	COG1846	Transcriptional regulator
CEG15_07165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEG15_07170	COG3108	Peptidase M15
CEG15_07175	COG2989	Protein conserved in bacteria
CEG15_07205	COG1940	carbohydrate kinase activity
CEG15_07215	COG0748	coenzyme F420 binding
CEG15_07220	COG3721	Heme iron utilization protein
CEG15_07225	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CEG15_07230	COG0811	peptide transport
CEG15_07235	COG0848	biopolymer transport protein
CEG15_07245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEG15_07250	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CEG15_07270	COG1621	beta-fructofuranosidase activity
CEG15_07280	COG1263	PTS System
CEG15_07280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEG15_07285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEG15_07290	COG2200	EAL domain
CEG15_07295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEG15_07300	COG0840	transmembrane signaling receptor activity
CEG15_07305	COG1294	oxidase, subunit
CEG15_07310	COG1271	oxidase subunit
CEG15_07335	COG3220	belongs to the UPF0276 family
CEG15_07355	COG1294	oxidase, subunit
CEG15_07365	COG0251	oxidation-reduction process
CEG15_07385	COG0745	RESPONSE REGULATOR receiver
CEG15_07385	COG3706	GGDEF domain
CEG15_07405	COG0784	Response regulator, receiver
CEG15_07405	COG0835	chemotaxis
CEG15_07415	COG4565	transcriptional regulatory protein
CEG15_07420	COG3290	protein histidine kinase activity
CEG15_07435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEG15_07460	COG3063	Type IV pilus biogenesis stability protein PilW
CEG15_07475	COG1451	nucleotide metabolic process
CEG15_07485	COG0583	DNA-binding transcription factor activity
CEG15_07510	COG4139	cobalamin transport
CEG15_07515	COG2988	succinylglutamate desuccinylase activity
CEG15_07530	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CEG15_07550	COG2994	toxin metabolic process
CEG15_07580	COG2925	Exonuclease
CEG15_07590	COG1346	cytolysis
CEG15_07595	COG0295	cytidine deaminase activity
CEG15_07600	COG5001	Diguanylate cyclase
CEG15_07605	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CEG15_07615	COG0500	methyltransferase
CEG15_07630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEG15_07630	COG0072	phenylalanine-tRNA ligase activity
CEG15_07675	COG0322	excinuclease ABC activity
CEG15_07680	COG2197	response regulator
CEG15_07685	COG0417	DNA replication proofreading
CEG15_07695	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEG15_07700	COG3099	Belongs to the UPF0263 family
CEG15_07715	COG1228	amidohydrolase
CEG15_07720	COG0010	Belongs to the arginase family
CEG15_07730	COG2986	histidine ammonia-lyase
CEG15_07745	COG0247	lactate metabolic process
CEG15_07745	COG0277	FAD linked oxidase domain protein
CEG15_07775	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEG15_07780	COG1960	acyl-CoA dehydrogenase activity
CEG15_07810	COG5001	Diguanylate cyclase
CEG15_07810	COG3300	MHYT domain
CEG15_07830	COG0784	Response regulator, receiver
CEG15_07830	COG5002	protein histidine kinase activity
CEG15_07845	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CEG15_07850	COG2885	chlorophyll binding
CEG15_07870	COG0811	peptide transport
CEG15_07875	COG0824	Thioesterase
CEG15_07880	COG3790	cyd operon protein YbgE
CEG15_07885	COG4890	Cyd operon protein YbgT
CEG15_07890	COG1294	oxidase, subunit
CEG15_07895	COG1271	oxidase subunit
CEG15_07900	COG2255	four-way junction helicase activity
CEG15_07905	COG0632	four-way junction helicase activity
CEG15_07910	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CEG15_07915	COG0215	cysteine-tRNA ligase activity
CEG15_07920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEG15_07925	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEG15_07930	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CEG15_07935	COG3012	SEC-C Motif Domain Protein
CEG15_07950	COG1199	ATP-dependent helicase activity
CEG15_07960	COG3923	Primosomal replication protein n
CEG15_07970	COG0840	transmembrane signaling receptor activity
CEG15_07975	COG0708	Exodeoxyribonuclease III
CEG15_07980	COG4160	amino acid transport
CEG15_07985	COG4215	(ABC) transporter
CEG15_08010	COG1882	Formate acetyltransferase
CEG15_08025	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEG15_08040	COG2766	serine protein kinase
CEG15_08045	COG2718	Belongs to the UPF0229 family
CEG15_08050	COG2719	SpoVR family
CEG15_08055	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CEG15_08070	COG1132	(ABC) transporter
CEG15_08075	COG2333	competence protein COMEC
CEG15_08075	COG0658	competence protein
CEG15_08085	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEG15_08090	COG1136	(ABC) transporter
CEG15_08095	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEG15_08105	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEG15_08120	COG1252	NADH dehydrogenase
CEG15_08150	COG0537	adenosine 5'-monophosphoramidase activity
CEG15_08165	COG2186	Transcriptional regulator
CEG15_08170	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CEG15_08180	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CEG15_08185	COG2226	methyltransferase
CEG15_08200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CEG15_08210	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEG15_08215	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CEG15_08220	COG0653	protein targeting
CEG15_08225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEG15_08235	COG4120	Belongs to the binding-protein-dependent transport system permease family
CEG15_08245	COG3092	negative regulation of chromosome organization
CEG15_08250	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEG15_08255	COG0280	phosphate acetyltransferase
CEG15_08255	COG0857	belongs to the CobB CobQ family
CEG15_08260	COG0435	Glutathione S-transferase
CEG15_08270	COG0444	Belongs to the ABC transporter superfamily
CEG15_08275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEG15_08280	COG0601	transmembrane transport
CEG15_08295	COG0784	Response regulator, receiver
CEG15_08295	COG5002	protein histidine kinase activity
CEG15_08320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEG15_08325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEG15_08345	COG1216	Glycosyl transferase, family 2
CEG15_08375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEG15_08380	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEG15_08385	COG1028	Short-chain dehydrogenase reductase Sdr
CEG15_08420	COG3555	Aspartyl Asparaginyl beta-hydroxylase
CEG15_08435	COG0800	Aldolase
CEG15_08440	COG2610	gluconate transmembrane transporter activity
CEG15_08445	COG3265	gluconokinase activity
CEG15_08450	COG0129	dihydroxy-acid dehydratase activity
CEG15_08455	COG1609	Transcriptional regulator
CEG15_08470	COG3850	Histidine kinase
CEG15_08470	COG5002	protein histidine kinase activity
CEG15_08480	COG2985	domain, Protein
CEG15_08495	COG2194	sulfuric ester hydrolase activity
CEG15_08500	COG0642	Histidine kinase
CEG15_08505	COG0745	RESPONSE REGULATOR receiver
CEG15_08515	COG4221	oxidoreductase activity
CEG15_08525	COG1022	Amp-dependent synthetase and ligase
CEG15_08550	COG2199	diguanylate cyclase activity
CEG15_08550	COG2203	Gaf domain
CEG15_08565	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CEG15_08570	COG1946	Acyl-CoA thioesterase
CEG15_08575	COG1522	sequence-specific DNA binding
CEG15_08615	COG0318	PFAM AMP-dependent synthetase and ligase
CEG15_08620	COG1441	menaquinone biosynthetic process
CEG15_08625	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CEG15_08635	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CEG15_08640	COG1169	isochorismate synthase
CEG15_08650	COG0436	Aminotransferase
CEG15_08655	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CEG15_08660	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CEG15_08675	COG0616	signal peptide processing
CEG15_08680	COG1028	Short-chain dehydrogenase reductase Sdr
CEG15_08685	COG0835	chemotaxis
CEG15_08685	COG0784	Response regulator, receiver
CEG15_08690	COG1940	carbohydrate kinase activity
CEG15_08700	COG4667	esterase of the alpha-beta hydrolase superfamily
CEG15_08710	COG0733	neurotransmitter:sodium symporter activity
CEG15_08720	COG1263	PTS System
CEG15_08720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEG15_08725	COG0084	hydrolase, TatD family'
CEG15_08730	COG0470	DNA polymerase III
CEG15_08735	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CEG15_08740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CEG15_08745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEG15_08770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEG15_08780	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CEG15_08785	COG1399	metal-binding, possibly nucleic acid-binding protein
CEG15_08790	COG0424	maF-like protein
CEG15_08795	COG0564	pseudouridine synthase activity
CEG15_08800	COG1530	ribonuclease E activity
CEG15_08810	COG1454	alcohol dehydrogenase
CEG15_08810	COG1012	belongs to the aldehyde dehydrogenase family
CEG15_08815	COG2095	MarC family integral membrane protein
CEG15_08820	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEG15_08825	COG1757	Na H antiporter
CEG15_08840	COG3082	Protein of unknown function (DUF1414)
CEG15_08845	COG3083	sulfuric ester hydrolase activity
CEG15_08855	COG0243	molybdopterin cofactor binding
CEG15_08860	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CEG15_08875	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEG15_08880	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CEG15_08900	COG2853	Lipoprotein
CEG15_08915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEG15_08920	COG1138	Cytochrome C-type biogenesis protein
CEG15_08925	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CEG15_08935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEG15_08940	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEG15_08945	COG4133	protoheme IX ABC transporter activity
CEG15_08955	COG0835	chemotaxis
CEG15_08965	COG1192	Involved in chromosome partitioning
CEG15_08970	COG2201	protein-glutamate methylesterase activity
CEG15_08975	COG2198	Histidine kinase
CEG15_08975	COG0643	Histidine kinase
CEG15_08980	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CEG15_08995	COG0455	bacterial-type flagellum organization
CEG15_09005	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CEG15_09010	COG2062	phosphohistidine phosphatase, SixA
CEG15_09015	COG1025	Belongs to the peptidase M16 family
CEG15_09020	COG3102	Protein conserved in bacteria
CEG15_09045	COG1918	ferrous iron import across plasma membrane
CEG15_09050	COG4977	sequence-specific DNA binding
CEG15_09055	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CEG15_09060	COG1121	(ABC) transporter
CEG15_09065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEG15_09080	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEG15_09085	COG0567	Dehydrogenase, E1 component
CEG15_09100	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CEG15_09105	COG2009	succinate dehydrogenase
CEG15_09115	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CEG15_09125	COG0033	Phosphoglucomutase
CEG15_09130	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CEG15_09135	COG0596	Alpha beta hydrolase
CEG15_09145	COG0716	FMN binding
CEG15_09150	COG1346	cytolysis
CEG15_09160	COG0583	DNA-binding transcription factor activity
CEG15_09170	COG0735	belongs to the Fur family
CEG15_09175	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEG15_09180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEG15_09185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEG15_09190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEG15_09190	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CEG15_09195	COG0431	NADPH-dependent FMN reductase
CEG15_09205	COG3101	peptidyl-lysine hydroxylation
CEG15_09210	COG2860	membrane
CEG15_09215	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CEG15_09220	COG2890	protein-(glutamine-N5) methyltransferase activity
CEG15_09225	COG2840	Smr protein MutS2
CEG15_09235	COG1684	flagellar biosynthetic protein fliR
CEG15_09240	COG1987	bacterial-type flagellum assembly
CEG15_09290	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CEG15_09300	COG1677	Flagellar hook-basal body complex protein FliE
CEG15_09305	COG2204	response regulator
CEG15_09310	COG4191	Histidine kinase
CEG15_09315	COG2204	response regulator
CEG15_09320	COG1516	flagellar protein fliS
CEG15_09330	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CEG15_09355	COG2837	iron assimilation
CEG15_09380	COG1393	Belongs to the ArsC family
CEG15_09385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEG15_09405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEG15_09415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEG15_09440	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEG15_09460	COG1196	nuclear chromosome segregation
CEG15_09465	COG1074	ATP-dependent DNA helicase activity
CEG15_09470	COG0210	DNA helicase
CEG15_09525	COG0537	adenosine 5'-monophosphoramidase activity
CEG15_09540	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CEG15_09545	COG0076	glutamate decarboxylase activity
CEG15_09565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEG15_09585	COG4783	chaperone-mediated protein folding
CEG15_09590	COG1393	Belongs to the ArsC family
CEG15_09610	COG2233	PERMEase
CEG15_09615	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEG15_09625	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CEG15_09630	COG2912	Transglutaminase-like superfamily
CEG15_09635	COG3094	Invasion gene expression up-regulator, SirB
CEG15_09640	COG2890	protein-(glutamine-N5) methyltransferase activity
CEG15_09645	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CEG15_09650	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CEG15_09655	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CEG15_09670	COG0193	aminoacyl-tRNA hydrolase activity
CEG15_09775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CEG15_09785	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEG15_09785	COG3951	Flagellar rod assembly protein muramidase FlgJ
CEG15_09790	COG1706	bacterial-type flagellum-dependent cell motility
CEG15_09795	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CEG15_09800	COG4786	Flagellar basal body rod
CEG15_09805	COG4787	bacterial-type flagellum-dependent cell motility
CEG15_09810	COG1749	Flagellar hook protein flgE
CEG15_09815	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CEG15_09820	COG1558	bacterial-type flagellum-dependent cell motility
CEG15_09825	COG1815	bacterial-type flagellum-dependent cell motility
CEG15_09835	COG0835	chemotaxis
CEG15_09835	COG0784	Response regulator, receiver
CEG15_09845	COG2747	anti-sigma28 factor FlgM
CEG15_09890	COG2217	Heavy metal translocating P-type atpase
CEG15_09890	COG2608	mercury ion transmembrane transporter activity
CEG15_09915	COG1187	pseudouridine synthase activity
CEG15_09920	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEG15_09925	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CEG15_09930	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CEG15_09935	COG0121	glutamine amidotransferase
CEG15_09940	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CEG15_09955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEG15_09965	COG2226	methyltransferase
CEG15_09970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEG15_09975	COG0741	lytic transglycosylase activity
CEG15_09975	COG1388	LysM domain
CEG15_09990	COG0347	Belongs to the P(II) protein family
CEG15_10000	COG0037	tRNA processing
CEG15_10005	COG0825	malonyl-CoA metabolic process
CEG15_10010	COG0587	DNA-directed DNA polymerase activity
CEG15_10020	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEG15_10030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEG15_10035	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEG15_10040	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CEG15_10050	COG0750	zinc metalloprotease
CEG15_10055	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CEG15_10060	COG0575	Belongs to the CDS family
CEG15_10065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CEG15_10070	COG0233	cytoplasmic translational termination
CEG15_10080	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CEG15_10085	COG0052	Belongs to the universal ribosomal protein uS2 family
CEG15_10090	COG0024	Methionine aminopeptidase
CEG15_10105	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CEG15_10110	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CEG15_10135	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEG15_10135	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEG15_10145	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CEG15_10150	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CEG15_10170	COG2252	PERMEase
CEG15_10175	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEG15_10180	COG0189	ligase activity
CEG15_10180	COG4067	protein conserved in archaea
CEG15_10185	COG0189	ligase activity
CEG15_10195	COG0733	neurotransmitter:sodium symporter activity
CEG15_10200	COG3706	GGDEF domain
CEG15_10200	COG4251	negative regulation of phosphorylation
CEG15_10200	COG5001	Diguanylate cyclase
CEG15_10200	COG2203	Gaf domain
CEG15_10210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEG15_10220	COG1477	protein flavinylation
CEG15_10255	COG0271	Belongs to the BolA IbaG family
CEG15_10275	COG2211	Major facilitator Superfamily
CEG15_10285	COG1595	DNA-templated transcription, initiation
CEG15_10300	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEG15_10310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CEG15_10315	COG2166	iron-sulfur cluster assembly
CEG15_10320	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CEG15_10325	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CEG15_10335	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CEG15_10335	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEG15_10345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEG15_10350	COG1074	ATP-dependent DNA helicase activity
CEG15_10355	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CEG15_10370	COG3141	response to X-ray
CEG15_10375	COG2171	N-acyltransferase activity
CEG15_10385	COG0456	acetyltransferase
CEG15_10405	COG1609	Transcriptional regulator
CEG15_10415	COG1085	galactose-1-phosphate uridylyltransferase
CEG15_10420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEG15_10425	COG0534	Mate efflux family protein
CEG15_10435	COG3437	response regulator, receiver
CEG15_10435	COG0784	Response regulator, receiver
CEG15_10440	COG1022	Amp-dependent synthetase and ligase
CEG15_10445	COG4628	conserved protein (DUF2132)
CEG15_10450	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEG15_10455	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CEG15_10465	COG0560	Phosphoserine phosphatase
CEG15_10475	COG0813	purine-nucleoside phosphorylase activity
CEG15_10480	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CEG15_10490	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CEG15_10495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEG15_10500	COG0084	hydrolase, TatD family'
CEG15_10510	COG1115	amino acid carrier protein
CEG15_10525	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CEG15_10530	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CEG15_10535	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CEG15_10540	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CEG15_10545	COG0083	homoserine kinase activity
CEG15_10560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CEG15_10565	COG0745	RESPONSE REGULATOR receiver
CEG15_10575	COG0784	Response regulator, receiver
CEG15_10575	COG5002	protein histidine kinase activity
CEG15_10575	COG2198	Histidine kinase
CEG15_10580	COG1242	4 iron, 4 sulfur cluster binding
CEG15_10585	COG0070	glutamate synthase
CEG15_10585	COG0069	glutamate synthase activity
CEG15_10585	COG0067	glutamate synthase
CEG15_10595	COG0070	glutamate synthase
CEG15_10595	COG0067	glutamate synthase
CEG15_10595	COG0069	glutamate synthase activity
CEG15_10600	COG0493	'glutamate synthase
CEG15_10620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEG15_10625	COG2860	membrane
CEG15_10630	COG0583	DNA-binding transcription factor activity
CEG15_10635	COG0730	response to heat
CEG15_10645	COG0505	Belongs to the CarA family
CEG15_10655	COG0494	nUDIX hydrolase
CEG15_10660	COG0653	protein targeting
CEG15_10670	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CEG15_10675	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CEG15_10680	COG0849	cell division
CEG15_10685	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CEG15_10690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEG15_10695	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CEG15_10700	COG0772	Belongs to the SEDS family
CEG15_10705	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CEG15_10710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEG15_10715	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEG15_10720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CEG15_10725	COG0768	penicillin binding
CEG15_10730	COG3116	cell division
CEG15_10745	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CEG15_10750	COG3107	peptidoglycan biosynthetic process
CEG15_10760	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CEG15_10770	COG2969	positive regulation of protein catabolic process
CEG15_10775	COG0625	glutathione transferase activity
CEG15_10780	COG2857	Cytochrome c1
CEG15_10785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CEG15_10790	COG0723	plastoquinol--plastocyanin reductase activity
CEG15_10810	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CEG15_10815	COG3105	Protein conserved in bacteria
CEG15_10820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEG15_10825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEG15_10830	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CEG15_10835	COG0187	DNA topoisomerase II activity
CEG15_10840	COG3150	esterase
CEG15_10850	COG3151	Protein conserved in bacteria
CEG15_10855	COG0494	nUDIX hydrolase
CEG15_10860	COG1538	Outer membrane efflux protein
CEG15_10870	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CEG15_10885	COG3025	triphosphatase activity
CEG15_10890	COG1392	Phosphate transport regulator
CEG15_10895	COG0306	phosphate transporter
CEG15_10900	COG4991	sh3 domain protein
CEG15_10910	COG3409	Peptidoglycan-binding domain 1 protein
CEG15_10910	COG3267	Type II secretory pathway component ExeA
CEG15_10915	COG0617	tRNA 3'-terminal CCA addition
CEG15_10925	COG0504	CTP synthase activity
CEG15_10930	COG3956	TIGRFAM MazG family protein
CEG15_10935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEG15_10940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEG15_10945	COG2205	protein histidine kinase activity
CEG15_10945	COG3437	response regulator, receiver
CEG15_10945	COG3850	Histidine kinase
CEG15_10945	COG4999	Histidine kinase
CEG15_10950	COG0736	holo-[acyl-carrier-protein] synthase activity
CEG15_10975	COG0681	Belongs to the peptidase S26 family
CEG15_10980	COG0481	GTPase activity
CEG15_10985	COG3086	response to oxidative stress
CEG15_11000	COG1595	DNA-templated transcription, initiation
CEG15_11005	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CEG15_11015	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CEG15_11020	COG0354	folic acid binding
CEG15_11035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEG15_11040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEG15_11050	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CEG15_11060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CEG15_11070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEG15_11080	COG0028	Belongs to the TPP enzyme family
CEG15_11085	COG1022	Amp-dependent synthetase and ligase
CEG15_11105	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEG15_11110	COG0473	3-isopropylmalate dehydrogenase activity
CEG15_11120	COG0066	3-isopropylmalate dehydratase activity
CEG15_11185	COG0795	lipopolysaccharide-transporting ATPase activity
CEG15_11190	COG0795	lipopolysaccharide-transporting ATPase activity
CEG15_11195	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEG15_11200	COG2927	DNA polymerase III (CHI subunit)
CEG15_11205	COG0525	valine-tRNA ligase activity
CEG15_11210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEG15_11215	COG0564	pseudouridine synthase activity
CEG15_11225	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEG15_11235	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CEG15_11250	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CEG15_11255	COG0251	oxidation-reduction process
CEG15_11270	COG0204	Acyl-transferase
CEG15_11275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEG15_11280	COG5007	Belongs to the BolA IbaG family
CEG15_11290	COG2854	intermembrane phospholipid transfer
CEG15_11295	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CEG15_11300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CEG15_11305	COG1127	ABC transporter
CEG15_11315	COG0517	IMP dehydrogenase activity
CEG15_11315	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CEG15_11320	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CEG15_11330	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CEG15_11335	COG1137	ATPase activity
CEG15_11345	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEG15_11350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_11360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_11365	COG2239	Acts as a magnesium transporter
CEG15_11370	COG0312	modulator of DNA gyrase
CEG15_11375	COG3028	Belongs to the UPF0307 family
CEG15_11380	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CEG15_11385	COG1178	ABC-type Fe3 transport system permease component
CEG15_11390	COG4143	(ABC) transporter
CEG15_11395	COG0163	prenyltransferase activity
CEG15_11400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEG15_11405	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CEG15_11410	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CEG15_11420	COG2105	PFAM AIG2 family protein
CEG15_11425	COG2911	Protein conserved in bacteria
CEG15_11430	COG0729	surface antigen
CEG15_11435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEG15_11440	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CEG15_11475	COG0529	Catalyzes the synthesis of activated sulfate
CEG15_11480	COG2895	sulfate adenylyltransferase (ATP) activity
CEG15_11485	COG0175	sulfate reduction
CEG15_11490	COG1648	precorrin-2 dehydrogenase activity
CEG15_11490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEG15_11495	COG0737	Belongs to the 5'-nucleotidase family
CEG15_11535	COG0513	Belongs to the DEAD box helicase family
CEG15_11540	COG2153	protein acetylation
CEG15_11545	COG3266	domain, Protein
CEG15_11545	COG3061	Opacity-associated protein A
CEG15_11550	COG0545	Peptidyl-prolyl cis-trans isomerase
CEG15_11555	COG0203	ribosomal protein L17
CEG15_11565	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CEG15_11570	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CEG15_11575	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEG15_11585	COG0201	protein transport
CEG15_11610	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CEG15_11615	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CEG15_11635	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CEG15_11640	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CEG15_11665	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CEG15_11690	COG0051	transcription antitermination factor activity, RNA binding
CEG15_11695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEG15_11700	COG0557	exoribonuclease II activity
CEG15_11705	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CEG15_11715	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEG15_11725	COG1047	Peptidyl-prolyl cis-trans
CEG15_11730	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CEG15_11740	COG2249	NAD(P)H dehydrogenase (quinone) activity
CEG15_11745	COG0488	(ABC) transporter
CEG15_11755	COG0429	hydrolase of the alpha beta-hydrolase fold
CEG15_11765	COG3954	Phosphoribulokinase
CEG15_11770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEG15_11790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEG15_11805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEG15_11815	COG0583	DNA-binding transcription factor activity
CEG15_11830	COG0180	Tryptophanyl-tRNA synthetase
CEG15_11835	COG0546	phosphoglycolate phosphatase activity
CEG15_11840	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEG15_11845	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CEG15_11860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CEG15_11890	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CEG15_11900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CEG15_11900	COG0678	peroxiredoxin activity
CEG15_11905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEG15_11915	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CEG15_11915	COG0165	Argininosuccinate lyase
CEG15_11925	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEG15_11930	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CEG15_11950	COG1045	serine acetyltransferase
CEG15_11955	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEG15_11965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEG15_11970	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CEG15_11975	COG1053	succinate dehydrogenase
CEG15_11980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CEG15_11985	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CEG15_11995	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEG15_12000	COG1509	lysine 2,3-aminomutase activity
CEG15_12020	COG3335	DDE superfamily endonuclease
CEG15_12030	COG0583	DNA-binding transcription factor activity
CEG15_12040	COG0459	protein refolding
CEG15_12070	COG0149	triose-phosphate isomerase activity
CEG15_12075	COG0534	Mate efflux family protein
CEG15_12080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CEG15_12085	COG1575	Belongs to the MenA family. Type 1 subfamily
CEG15_12105	COG1609	Transcriptional regulator
CEG15_12110	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEG15_12120	COG0281	malic enzyme
CEG15_12130	COG0626	cystathionine gamma-synthase activity
CEG15_12135	COG0527	aspartate kinase activity
CEG15_12135	COG0460	homoserine dehydrogenase
CEG15_12140	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CEG15_12150	COG1494	fructose-1,6-bisphosphatase
CEG15_12155	COG0205	6-phosphofructokinase activity
CEG15_12160	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CEG15_12170	COG0745	RESPONSE REGULATOR receiver
CEG15_12175	COG2205	protein histidine kinase activity
CEG15_12180	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CEG15_12185	COG1278	Cold shock
CEG15_12190	COG3030	protein affecting phage T7 exclusion by the F plasmid
CEG15_12195	COG1027	Aspartate ammonia-lyase
CEG15_12200	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CEG15_12205	COG1288	antiporter activity
CEG15_12215	COG0549	Belongs to the carbamate kinase family
CEG15_12220	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CEG15_12230	COG0540	Belongs to the ATCase OTCase family
CEG15_12235	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CEG15_12240	COG1438	arginine binding
CEG15_12245	COG4232	protein-disulfide reductase activity
CEG15_12255	COG3263	regulation of cellular component size
CEG15_12265	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEG15_12270	COG2205	protein histidine kinase activity
CEG15_12270	COG0784	Response regulator, receiver
CEG15_12270	COG2198	Histidine kinase
CEG15_12275	COG2814	Major facilitator Superfamily
CEG15_12290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEG15_12295	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CEG15_12300	COG0511	ligase activity, forming carbon-carbon bonds
CEG15_12305	COG0439	Biotin carboxylase
CEG15_12310	COG2264	protein methyltransferase activity
CEG15_12315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEG15_12320	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CEG15_12325	COG0840	transmembrane signaling receptor activity
CEG15_12330	COG0789	Transcriptional regulator
CEG15_12340	COG0151	Belongs to the GarS family
CEG15_12350	COG0776	regulation of translation
CEG15_12355	COG1253	flavin adenine dinucleotide binding
CEG15_12370	COG3068	Protein conserved in bacteria
CEG15_12375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEG15_12380	COG0668	transmembrane transport
CEG15_12385	COG0840	transmembrane signaling receptor activity
CEG15_12390	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CEG15_12395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEG15_12425	COG0438	transferase activity, transferring glycosyl groups
CEG15_12440	COG1216	Glycosyl transferase, family 2
CEG15_12480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEG15_12505	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEG15_12515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEG15_12540	COG3754	Rhamnan synthesis protein F
CEG15_12570	COG0463	Glycosyl transferase, family 2
CEG15_12580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CEG15_12590	COG0028	Belongs to the TPP enzyme family
CEG15_12605	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CEG15_12625	COG5433	transposase activity
CEG15_12640	COG1682	transport, permease protein
CEG15_12675	COG3307	-O-antigen
CEG15_12680	COG0859	PFAM glycosyl transferase family 9
CEG15_12695	COG1519	Transferase
CEG15_12705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CEG15_12720	COG3642	lipopolysaccharide core region biosynthetic process
CEG15_12725	COG0859	PFAM glycosyl transferase family 9
CEG15_12730	COG0463	Glycosyl transferase, family 2
CEG15_12735	COG0859	PFAM glycosyl transferase family 9
CEG15_12740	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CEG15_12745	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CEG15_12755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEG15_12770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEG15_12775	COG1309	transcriptional regulator
CEG15_12780	COG1560	Kdo2-lipid A biosynthetic process
CEG15_12785	COG1560	Kdo2-lipid A biosynthetic process
CEG15_12795	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CEG15_12800	COG1561	YicC-like family, N-terminal region
CEG15_12810	COG0612	Peptidase, M16
CEG15_12830	COG1120	ATPase activity
CEG15_12835	COG4774	siderophore transport
CEG15_12840	COG1132	(ABC) transporter
CEG15_12845	COG1263	PTS System
CEG15_12845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEG15_12850	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEG15_12870	COG0514	ATP-dependent DNA helicase (RecQ)
CEG15_12875	COG2962	Rard protein
CEG15_12880	COG0405	Gamma-glutamyltransferase
CEG15_12890	COG1280	lysine exporter protein (LysE YggA)
CEG15_12895	COG0210	DNA helicase
CEG15_12900	COG0339	signal peptide processing
CEG15_12905	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CEG15_12910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEG15_12930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEG15_12985	COG1309	transcriptional regulator
CEG15_12990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEG15_12995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEG15_13000	COG2960	long-chain fatty acid transporting porin activity
CEG15_13010	COG0583	DNA-binding transcription factor activity
CEG15_13015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEG15_13040	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CEG15_13045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEG15_13045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEG15_13055	COG0084	hydrolase, TatD family'
CEG15_13060	COG0805	protein transport
CEG15_13065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEG15_13075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CEG15_13090	COG1322	Protein conserved in bacteria
CEG15_13110	COG2160	L-arabinose isomerase activity
CEG15_13120	COG1069	ribulokinase activity
CEG15_13130	COG1879	ABC-type sugar transport system periplasmic component
CEG15_13135	COG1129	ABC transporter
CEG15_13140	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEG15_13180	COG2124	cytochrome p450
CEG15_13185	COG0477	Major facilitator Superfamily
CEG15_13195	COG0251	oxidation-reduction process
CEG15_13205	COG0251	oxidation-reduction process
CEG15_13210	COG3048	D-serine ammonia-lyase activity
CEG15_13215	COG2610	gluconate transmembrane transporter activity
CEG15_13220	COG0583	DNA-binding transcription factor activity
CEG15_13275	COG2081	HI0933 family
CEG15_13290	COG1528	Iron-storage protein
CEG15_13295	COG0589	response to stress
CEG15_13300	COG0697	spore germination
CEG15_13310	COG0742	ribosomal rna small subunit methyltransferase
CEG15_13315	COG1522	sequence-specific DNA binding
CEG15_13335	COG0006	proline dipeptidase activity
CEG15_13335	COG0006	proline dipeptidase activity
CEG15_13340	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CEG15_13350	COG2104	thiamine diphosphate biosynthetic process
CEG15_13355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEG15_13360	COG0352	thiamine-phosphate diphosphorylase activity
CEG15_13450	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CEG15_13455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEG15_13460	COG1739	Uncharacterized protein family UPF0029
CEG15_13470	COG0183	Belongs to the thiolase family
CEG15_13475	COG0583	DNA-binding transcription factor activity
CEG15_13480	COG2814	Major facilitator Superfamily
CEG15_13490	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CEG15_13495	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEG15_13500	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEG15_13505	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEG15_13510	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEG15_13515	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEG15_13525	COG0356	it plays a direct role in the translocation of protons across the membrane
CEG15_13530	COG3312	ion transport
CEG15_13535	COG1475	DNA binding
CEG15_13540	COG1192	Involved in chromosome partitioning
CEG15_13550	COG0445	tRNA wobble uridine modification
CEG15_13580	COG2084	Dehydrogenase
CEG15_13585	COG0814	amino acid
CEG15_13615	COG0583	DNA-binding transcription factor activity
CEG15_13620	COG2910	NAD(P)H-binding
CEG15_13630	COG3304	Inner membrane component domain
CEG15_13650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEG15_13655	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CEG15_13675	COG0363	glucosamine-6-phosphate deaminase activity
CEG15_13685	COG0739	heme binding
CEG15_13690	COG2213	PTS system mannitol-specific
CEG15_13690	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_13695	COG0246	Mannitol dehydrogenase
CEG15_13700	COG3722	fumarate hydratase activity
CEG15_13710	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CEG15_13715	COG1301	dicarboxylic acid transport
CEG15_13720	COG2259	Doxx family
CEG15_13745	COG1846	Transcriptional regulator
CEG15_13755	COG3046	protein related to deoxyribodipyrimidine photolyase
CEG15_13760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEG15_13765	COG0842	Transport permease protein
CEG15_13770	COG1131	(ABC) transporter
CEG15_13785	COG3842	ATPase activity
CEG15_13795	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEG15_13815	COG0513	Belongs to the DEAD box helicase family
CEG15_13820	COG0251	oxidation-reduction process
CEG15_13825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEG15_13835	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEG15_13840	COG1328	CTP reductase activity
CEG15_13850	COG2130	NADP-dependent
CEG15_13855	COG1309	transcriptional regulator
CEG15_13870	COG0745	RESPONSE REGULATOR receiver
CEG15_13880	COG0564	pseudouridine synthase activity
CEG15_13965	COG3501	Rhs element vgr protein
CEG15_14015	COG0471	metal ion transport
CEG15_14020	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CEG15_14030	COG2188	Transcriptional regulator
CEG15_14035	COG1131	(ABC) transporter
CEG15_14045	COG0840	transmembrane signaling receptor activity
CEG15_14065	COG0671	phosphoesterase, PA-phosphatase related
CEG15_14070	COG4399	Belongs to the UPF0754 family
CEG15_14075	COG1132	(ABC) transporter
CEG15_14095	COG3623	hexulose-6-phosphate isomerase
CEG15_14100	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CEG15_14105	COG0561	phosphatase activity
CEG15_14165	COG0366	Alpha amylase catalytic
CEG15_14175	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CEG15_14185	COG1999	signal sequence binding
CEG15_14205	COG0786	glutamate:sodium symporter activity
CEG15_14230	COG1566	PFAM secretion protein HlyD family protein
CEG15_14240	COG3706	GGDEF domain
CEG15_14255	COG0813	purine-nucleoside phosphorylase activity
CEG15_14260	COG3272	Protein of unknown function (DUF1722)
CEG15_14265	COG0789	Transcriptional regulator
CEG15_14270	COG0415	Belongs to the DNA photolyase family
CEG15_14275	COG1388	LysM domain
CEG15_14275	COG1376	ErfK ybiS ycfS ynhG family protein
CEG15_14285	COG0513	Belongs to the DEAD box helicase family
CEG15_14315	COG2267	carboxylic ester hydrolase activity
CEG15_14325	COG0366	Alpha amylase catalytic
CEG15_14330	COG4989	oxidoreductase activity
CEG15_14340	COG1136	(ABC) transporter
CEG15_14340	COG0577	efflux transmembrane transporter activity
CEG15_14345	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEG15_14360	COG0745	RESPONSE REGULATOR receiver
CEG15_14360	COG2972	Histidine kinase
CEG15_14365	COG3279	Response regulator of the LytR AlgR family
CEG15_14370	COG4251	negative regulation of phosphorylation
CEG15_14370	COG5001	Diguanylate cyclase
CEG15_14370	COG2203	Gaf domain
CEG15_14370	COG3706	GGDEF domain
CEG15_14380	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CEG15_14390	COG3437	response regulator, receiver
CEG15_14395	COG4999	Histidine kinase
CEG15_14395	COG3850	Histidine kinase
CEG15_14395	COG2205	protein histidine kinase activity
CEG15_14395	COG3437	response regulator, receiver
CEG15_14405	COG0531	amino acid
CEG15_14425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEG15_14435	COG0784	Response regulator, receiver
CEG15_14435	COG2205	protein histidine kinase activity
CEG15_14435	COG5002	protein histidine kinase activity
CEG15_14455	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEG15_14465	COG1609	Transcriptional regulator
CEG15_14490	COG0673	inositol 2-dehydrogenase activity
CEG15_14495	COG1765	OsmC-like protein
CEG15_14500	COG0110	maltose O-acetyltransferase activity
CEG15_14515	COG0583	DNA-binding transcription factor activity
CEG15_14525	COG0583	DNA-binding transcription factor activity
CEG15_14530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEG15_14535	COG3186	Phenylalanine-4-hydroxylase
CEG15_14545	COG0840	transmembrane signaling receptor activity
CEG15_14550	COG0534	Mate efflux family protein
CEG15_14555	COG2207	Transcriptional regulator
CEG15_14560	COG3437	response regulator, receiver
CEG15_14560	COG0784	Response regulator, receiver
CEG15_14565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEG15_14565	COG4191	Histidine kinase
CEG15_14575	COG2814	Major facilitator Superfamily
CEG15_14585	COG0443	Heat shock 70 kDa protein
CEG15_14600	COG3240	lipase activity
CEG15_14610	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CEG15_14615	COG5380	lipid catabolic process
CEG15_14620	COG3291	Pkd domain containing protein
CEG15_14620	COG4412	M6 family metalloprotease domain protein
CEG15_14645	COG4607	ABC-type enterochelin transport system periplasmic component
CEG15_14650	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEG15_14655	COG4605	iron ion homeostasis
CEG15_14660	COG4604	ABC transporter, ATP-binding protein
CEG15_14675	COG2153	protein acetylation
CEG15_14680	COG0697	spore germination
CEG15_14685	COG0387	Pfam Sodium calcium exchanger
CEG15_14690	COG0861	Integral membrane protein TerC family
CEG15_14705	COG3706	GGDEF domain
CEG15_14710	COG4974	Belongs to the 'phage' integrase family
CEG15_14740	COG1192	Involved in chromosome partitioning
CEG15_14765	COG3344	reverse transcriptase
CEG15_14780	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CEG15_14800	COG3344	reverse transcriptase
CEG15_14825	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEG15_14835	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CEG15_14850	COG0612	Peptidase, M16
CEG15_14865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEG15_14865	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CEG15_14865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEG15_14870	COG1105	Belongs to the carbohydrate kinase PfkB family
CEG15_14875	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_14875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_14880	COG1609	Transcriptional regulator
CEG15_14885	COG0420	3'-5' exonuclease activity
CEG15_14890	COG0419	ATPase involved in DNA repair
CEG15_14895	COG2205	protein histidine kinase activity
CEG15_14895	COG0784	Response regulator, receiver
CEG15_14900	COG0156	8-amino-7-oxononanoate synthase activity
CEG15_14910	COG0038	chloride channel
CEG15_14915	COG0523	cobalamin synthesis protein
CEG15_14930	COG1136	(ABC) transporter
CEG15_14930	COG0577	efflux transmembrane transporter activity
CEG15_14945	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CEG15_14975	COG3730	PTS system glucitol sorbitol-specific
CEG15_14990	COG1028	Short-chain dehydrogenase reductase Sdr
CEG15_14995	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_15000	COG1349	DNA-binding transcription factor activity
CEG15_15005	COG3730	PTS system glucitol sorbitol-specific
CEG15_15020	COG3842	ATPase activity
CEG15_15030	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEG15_15040	COG2182	Extracellular solute-binding protein
CEG15_15045	COG1175	transmembrane transport
CEG15_15050	COG3833	ABC-type maltose transport systems, permease component
CEG15_15075	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEG15_15080	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEG15_15090	COG3005	denitrification pathway
CEG15_15100	COG0243	molybdopterin cofactor binding
CEG15_15110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEG15_15115	COG3850	Histidine kinase
CEG15_15120	COG2197	response regulator
CEG15_15125	COG3069	C4-dicarboxylate transmembrane transporter activity
CEG15_15150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEG15_15160	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CEG15_15165	COG0513	Belongs to the DEAD box helicase family
CEG15_15235	COG1484	DNA-dependent DNA replication
CEG15_15285	COG3772	lysozyme
CEG15_15425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CEG15_15485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEG15_15490	COG0242	peptide deformylase activity
CEG15_15525	COG0346	lactoylglutathione lyase activity
CEG15_15555	COG0625	glutathione transferase activity
CEG15_15580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEG15_15680	COG2161	toxin-antitoxin pair type II binding
CEG15_15685	COG4115	mRNA cleavage
CEG15_15710	COG0454	-acetyltransferase
CEG15_15755	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEG15_15785	COG1028	Short-chain dehydrogenase reductase Sdr
CEG15_15830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEG15_15880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEG15_15915	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CEG15_15985	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CEG15_15990	COG2944	sequence-specific DNA binding
CEG15_15995	COG0724	RNA recognition motif
CEG15_16000	COG0724	RNA recognition motif
CEG15_16075	COG2161	toxin-antitoxin pair type II binding
CEG15_16080	COG4115	mRNA cleavage
CEG15_16565	COG3040	lipid binding
CEG15_16570	COG5433	transposase activity
CEG15_16585	COG0456	acetyltransferase
CEG15_16595	COG0110	maltose O-acetyltransferase activity
CEG15_16715	COG0724	RNA recognition motif
CEG15_16725	COG1196	nuclear chromosome segregation
CEG15_16730	COG0406	alpha-ribazole phosphatase activity
CEG15_16875	COG0346	lactoylglutathione lyase activity
CEG15_16890	COG0346	lactoylglutathione lyase activity
CEG15_16930	COG0583	DNA-binding transcription factor activity
CEG15_16995	COG0384	phenazine biosynthesis protein PhzF
CEG15_17010	COG1028	Short-chain dehydrogenase reductase Sdr
CEG15_17080	COG0023	Translation Initiation Factor
CEG15_17095	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEG15_17105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEG15_17105	COG1042	CoA-binding domain protein
CEG15_17105	COG0045	succinate-CoA ligase (ADP-forming) activity
CEG15_17110	COG0583	DNA-binding transcription factor activity
CEG15_17130	COG3140	Belongs to the UPF0181 family
CEG15_17145	COG0745	RESPONSE REGULATOR receiver
CEG15_17155	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CEG15_17160	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CEG15_17175	COG3706	GGDEF domain
CEG15_17180	COG1278	Cold shock
CEG15_17190	COG0840	transmembrane signaling receptor activity
CEG15_17205	COG2501	S4 domain
CEG15_17210	COG0625	glutathione transferase activity
CEG15_17215	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CEG15_17220	COG0488	(ABC) transporter
CEG15_17235	COG2050	protein possibly involved in aromatic compounds catabolism
CEG15_17245	COG2824	Alkylphosphonate utilization operon protein PhnA
CEG15_17255	COG0861	Integral membrane protein TerC family
CEG15_17260	COG0737	Belongs to the 5'-nucleotidase family
CEG15_17265	COG3593	DNA synthesis involved in DNA repair
CEG15_17275	COG0583	DNA-binding transcription factor activity
CEG15_17280	COG2116	formate transmembrane transporter activity
CEG15_17300	COG2188	Transcriptional regulator
CEG15_17305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEG15_17310	COG1011	Hydrolase
CEG15_17315	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CEG15_17325	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CEG15_17330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEG15_17335	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CEG15_17340	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEG15_17340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEG15_17345	COG0302	gtp cyclohydrolase
CEG15_17350	COG0303	'Molybdopterin
CEG15_17355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEG15_17360	COG2897	thiosulfate sulfurtransferase activity
CEG15_17380	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEG15_17395	COG0545	Peptidyl-prolyl cis-trans isomerase
CEG15_17400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEG15_17405	COG0840	transmembrane signaling receptor activity
CEG15_17410	COG2353	YceI-like domain
CEG15_17415	COG3038	cytochrome b561
CEG15_17425	COG5001	Diguanylate cyclase
CEG15_17425	COG2203	Gaf domain
CEG15_17425	COG3706	GGDEF domain
CEG15_17425	COG4251	negative regulation of phosphorylation
CEG15_17430	COG4172	Belongs to the ABC transporter superfamily
CEG15_17435	COG4239	(ABC) transporter, permease
CEG15_17440	COG4174	ABC transporter (Permease)
CEG15_17445	COG4166	transmembrane transport
CEG15_17460	COG4067	protein conserved in archaea
CEG15_17460	COG0189	ligase activity
CEG15_17470	COG0602	queuosine metabolic process
CEG15_17475	COG1328	CTP reductase activity
CEG15_17480	COG3706	GGDEF domain
CEG15_17505	COG0640	Transcriptional regulator
CEG15_17525	COG3300	MHYT domain
CEG15_17525	COG5001	Diguanylate cyclase
CEG15_17530	COG4191	Histidine kinase
CEG15_17535	COG3852	Histidine kinase
CEG15_17545	COG0745	RESPONSE REGULATOR receiver
CEG15_17560	COG2203	Gaf domain
CEG15_17560	COG3706	GGDEF domain
CEG15_17560	COG4251	negative regulation of phosphorylation
CEG15_17560	COG5001	Diguanylate cyclase
CEG15_17570	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CEG15_17575	COG4149	molybdate abc transporter
CEG15_17580	COG0725	ABC transporter, periplasmic molybdate-binding protein
CEG15_17585	COG1492	cobalamin metabolic process
CEG15_17590	COG3111	PFAM Bacterial OB fold (BOF) protein
CEG15_17600	COG3447	MASE1 domain protein
CEG15_17600	COG5001	Diguanylate cyclase
CEG15_17600	COG5002	protein histidine kinase activity
CEG15_17605	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEG15_17615	COG2207	Transcriptional regulator
CEG15_17620	COG1979	alcohol dehydrogenase
CEG15_17655	COG2205	protein histidine kinase activity
CEG15_17655	COG2198	Histidine kinase
CEG15_17655	COG0784	Response regulator, receiver
CEG15_17660	COG1879	ABC-type sugar transport system periplasmic component
CEG15_17665	COG1803	Methylglyoxal synthase
CEG15_17670	COG0210	DNA helicase
CEG15_17675	COG1289	transmembrane transporter activity
CEG15_17705	COG0784	Response regulator, receiver
CEG15_17705	COG5002	protein histidine kinase activity
CEG15_17720	COG2827	Endonuclease containing a URI domain
CEG15_17745	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEG15_17750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEG15_17755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CEG15_17760	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CEG15_17765	COG0247	lactate metabolic process
CEG15_17770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEG15_17775	COG3118	belongs to the thioredoxin family
CEG15_17795	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEG15_17810	COG2146	nitrite reductase [NAD(P)H] activity
CEG15_17815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEG15_17855	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CEG15_17870	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CEG15_17880	COG0513	Belongs to the DEAD box helicase family
CEG15_17885	COG0814	amino acid
CEG15_17895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEG15_17900	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CEG15_17910	COG1984	allophanate hydrolase subunit 2
CEG15_17920	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CEG15_17925	COG4181	ATPase activity
CEG15_17935	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEG15_17940	COG5001	Diguanylate cyclase
CEG15_17940	COG1716	ATPase activity
CEG15_17950	COG0484	heat shock protein binding
CEG15_17970	COG3437	response regulator, receiver
CEG15_17970	COG0784	Response regulator, receiver
CEG15_17985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEG15_17990	COG3300	MHYT domain
CEG15_17990	COG5001	Diguanylate cyclase
CEG15_18010	COG0010	Belongs to the arginase family
CEG15_18015	COG1166	arginine decarboxylase activity
CEG15_18030	COG4176	ABC-type proline glycine betaine transport system permease component
CEG15_18035	COG2113	Glycine betaine
CEG15_18060	COG0527	aspartate kinase activity
CEG15_18065	COG0662	Cupin 2, conserved barrel domain protein
CEG15_18070	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CEG15_18075	COG0456	acetyltransferase
CEG15_18085	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CEG15_18125	COG0366	Alpha amylase catalytic
CEG15_18145	COG0714	Associated with various cellular activities
CEG15_18165	COG2304	oxidoreductase activity
CEG15_18180	COG3706	GGDEF domain
CEG15_18190	COG1403	HNH endonuclease
CEG15_18205	COG1368	sulfuric ester hydrolase activity
CEG15_18215	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEG15_18220	COG3227	Zinc metalloprotease (Elastase)
CEG15_18235	COG2258	MOSC domain
CEG15_18265	COG1063	alcohol dehydrogenase
CEG15_18270	COG0156	8-amino-7-oxononanoate synthase activity
CEG15_18280	COG0346	lactoylglutathione lyase activity
CEG15_18295	COG2197	response regulator
CEG15_18300	COG3851	Histidine kinase
CEG15_18305	COG2271	Major facilitator Superfamily
CEG15_18340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEG15_18345	COG0640	Transcriptional regulator
CEG15_18350	COG0798	PFAM Bile acid sodium symporter
CEG15_18355	COG0640	Transcriptional regulator
CEG15_18360	COG0659	secondary active sulfate transmembrane transporter activity
CEG15_18365	COG0589	response to stress
CEG15_18390	COG4977	sequence-specific DNA binding
CEG15_18390	COG1917	Cupin 2, conserved barrel domain protein
CEG15_18395	COG4771	TonB-dependent receptor
CEG15_18400	COG2814	Major facilitator Superfamily
CEG15_18405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEG15_18405	COG2226	methyltransferase
CEG15_18405	COG3433	isochorismatase activity
CEG15_18430	COG1021	2,3-dihydroxybenzoate-AMP ligase
CEG15_18435	COG1132	(ABC) transporter
CEG15_18440	COG1132	(ABC) transporter
CEG15_18470	COG0542	response to heat
CEG15_18515	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEG15_18525	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CEG15_18530	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CEG15_18535	COG2204	response regulator
CEG15_18595	COG0516	GMP reductase activity
CEG15_18600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEG15_18625	COG1278	Cold shock
CEG15_18630	COG4681	YaeQ
CEG15_18635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEG15_18635	COG1017	nitric oxide dioxygenase activity
CEG15_18640	COG3604	Transcriptional regulator
CEG15_18655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEG15_18660	COG3217	Mosc domain protein beta barrel domain protein
CEG15_18660	COG0633	Ferredoxin
CEG15_18670	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEG15_18675	COG2354	Protein conserved in bacteria
CEG15_18700	COG3706	GGDEF domain
CEG15_18705	COG1349	DNA-binding transcription factor activity
CEG15_18735	COG1175	transmembrane transport
CEG15_18750	COG3842	ATPase activity
CEG15_18760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEG15_18765	COG0835	chemotaxis
CEG15_18765	COG0784	Response regulator, receiver
CEG15_18770	COG2315	Protein conserved in bacteria
CEG15_18775	COG3706	GGDEF domain
CEG15_18810	COG5001	Diguanylate cyclase
CEG15_18820	COG1741	Belongs to the pirin family
CEG15_18840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEG15_18850	COG0765	amino acid transport
CEG15_18855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEG15_18860	COG0765	amino acid transport
CEG15_18865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEG15_18880	COG0179	Fumarylacetoacetate (FAA) hydrolase
CEG15_18890	COG0697	spore germination
CEG15_18910	COG2814	Major facilitator Superfamily
CEG15_18915	COG0583	DNA-binding transcription factor activity
CEG15_18920	COG5001	Diguanylate cyclase
CEG15_18925	COG0739	heme binding
CEG15_18935	COG0659	secondary active sulfate transmembrane transporter activity
CEG15_18955	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEG15_18960	COG0581	inorganic phosphate transmembrane transporter activity
CEG15_18965	COG0573	inorganic phosphate transmembrane transporter activity
CEG15_18970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEG15_18980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEG15_18985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEG15_19005	COG3047	cAMP biosynthetic process
CEG15_19015	COG3397	chitin binding
CEG15_19020	COG2271	Major facilitator Superfamily
CEG15_19025	COG0584	glycerophosphoryl diester phosphodiesterase
CEG15_19035	COG3527	Alpha-acetolactate decarboxylase
CEG15_19050	COG0488	(ABC) transporter
CEG15_19060	COG3708	Transcriptional regulator
CEG15_19060	COG2207	Transcriptional regulator
CEG15_19065	COG0583	DNA-binding transcription factor activity
CEG15_19070	COG1620	l-lactate permease
CEG15_19075	COG1304	FMN binding
CEG15_19090	COG1881	PFAM PEBP family protein
CEG15_19095	COG3122	Protein conserved in bacteria
CEG15_19105	COG3568	Endonuclease Exonuclease Phosphatase
CEG15_19120	COG0840	transmembrane signaling receptor activity
CEG15_19130	COG1943	Transposase
CEG15_19135	COG1609	Transcriptional regulator
CEG15_19145	COG3842	ATPase activity
CEG15_19150	COG0395	ABC-type sugar transport system, permease component
CEG15_19155	COG1175	transmembrane transport
CEG15_19165	COG1609	Transcriptional regulator
CEG15_19170	COG4580	involved in the transport of maltose and maltodextrins
CEG15_19190	COG2211	Major facilitator Superfamily
CEG15_19200	COG1067	ATP-dependent peptidase activity
CEG15_19210	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CEG15_19215	COG0363	glucosamine-6-phosphate deaminase activity
CEG15_19225	COG0583	DNA-binding transcription factor activity
CEG15_19240	COG1609	Transcriptional regulator
CEG15_19245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEG15_19250	COG1879	ABC-type sugar transport system periplasmic component
CEG15_19255	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEG15_19260	COG1129	ABC transporter
CEG15_19265	COG1869	D-ribose catabolic process
CEG15_19280	COG3501	Rhs element vgr protein
CEG15_19290	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CEG15_19295	COG1640	4-alpha-glucanotransferase
CEG15_19300	COG0058	SHG alpha-glucan phosphorylase activity
CEG15_19305	COG2909	trisaccharide binding
CEG15_19330	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEG15_19350	COG0840	transmembrane signaling receptor activity
CEG15_19385	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CEG15_19395	COG0259	pyridoxamine-phosphate oxidase activity
CEG15_19425	COG0745	RESPONSE REGULATOR receiver
CEG15_19425	COG3706	GGDEF domain
CEG15_19445	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CEG15_19450	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CEG15_19455	COG0840	transmembrane signaling receptor activity
CEG15_19465	COG0835	chemotaxis
CEG15_19470	COG2198	Histidine kinase
CEG15_19470	COG0643	Histidine kinase
CEG15_19475	COG0745	RESPONSE REGULATOR receiver
CEG15_19485	COG1444	tRNA N-acetyltransferase activity
CEG15_19490	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine