locus-tag	class	description
CK207_00005	COG0445	tRNA wobble uridine modification
CK207_00015	COG1192	Involved in chromosome partitioning
CK207_00020	COG1475	DNA binding
CK207_00025	COG3312	ion transport
CK207_00030	COG0356	it plays a direct role in the translocation of protons across the membrane
CK207_00040	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CK207_00045	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CK207_00050	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CK207_00055	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CK207_00060	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CK207_00065	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CK207_00075	COG2814	Major facilitator Superfamily
CK207_00080	COG0583	DNA-binding transcription factor activity
CK207_00085	COG0183	Belongs to the thiolase family
CK207_00095	COG1739	Uncharacterized protein family UPF0029
CK207_00100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CK207_00105	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CK207_00150	COG0352	thiamine-phosphate diphosphorylase activity
CK207_00160	COG2104	thiamine diphosphate biosynthetic process
CK207_00170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CK207_00175	COG0006	proline dipeptidase activity
CK207_00175	COG0006	proline dipeptidase activity
CK207_00195	COG1522	sequence-specific DNA binding
CK207_00200	COG0742	ribosomal rna small subunit methyltransferase
CK207_00210	COG0697	spore germination
CK207_00215	COG0589	response to stress
CK207_00220	COG1528	Iron-storage protein
CK207_00235	COG2081	HI0933 family
CK207_00270	COG0784	Response regulator, receiver
CK207_00270	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CK207_00300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CK207_00305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CK207_00310	COG3385	transposase activity
CK207_00325	COG3084	Protein conserved in bacteria
CK207_00335	COG1272	protein, Hemolysin III
CK207_00345	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CK207_00350	COG0569	domain protein
CK207_00355	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CK207_00355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CK207_00360	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CK207_00365	COG0242	peptide deformylase activity
CK207_00370	COG1652	LysM domain
CK207_00375	COG0758	DNA mediated transformation
CK207_00380	COG2922	Belongs to the Smg family
CK207_00385	COG0551	DNA topoisomerase type I activity
CK207_00390	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CK207_00395	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CK207_00400	COG0009	L-threonylcarbamoyladenylate synthase
CK207_00405	COG0408	coproporphyrinogen oxidase activity
CK207_00410	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CK207_00420	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CK207_00455	COG3071	HemY protein
CK207_00460	COG2959	enzyme of heme biosynthesis
CK207_00465	COG1587	Uroporphyrinogen-III synthase
CK207_00475	COG3072	Adenylate cyclase
CK207_00490	COG0019	diaminopimelate decarboxylase activity
CK207_00505	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CK207_00510	COG1011	Hydrolase
CK207_00525	COG0561	phosphatase activity
CK207_00530	COG2267	carboxylic ester hydrolase activity
CK207_00535	COG1280	lysine exporter protein (LysE YggA)
CK207_00540	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CK207_00545	COG0783	Belongs to the Dps family
CK207_00575	COG2095	MarC family integral membrane protein
CK207_00590	COG2433	Pfam Transposase IS66
CK207_00605	COG4372	Transposase
CK207_00615	COG2433	Pfam Transposase IS66
CK207_00650	COG3335	DDE superfamily endonuclease
CK207_00670	COG0742	ribosomal rna small subunit methyltransferase
CK207_00675	COG0552	protein localization to endoplasmic reticulum
CK207_00680	COG2884	Cell division ATP-binding protein ftsE
CK207_00685	COG2177	Part of the ABC transporter FtsEX involved in
CK207_00690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CK207_00700	COG0705	Rhomboid family
CK207_00705	COG1580	Controls the rotational direction of flagella during chemotaxis
CK207_00710	COG3161	chorismate lyase activity
CK207_00720	COG2937	Belongs to the GPAT DAPAT family
CK207_00735	COG0534	Mate efflux family protein
CK207_00760	COG3250	beta-galactosidase activity
CK207_00800	COG0328	RNA-DNA hybrid ribonuclease activity
CK207_00845	COG2003	Belongs to the UPF0758 family
CK207_00870	COG2433	Pfam Transposase IS66
CK207_00910	COG2433	Pfam Transposase IS66
CK207_00920	COG0210	DNA helicase
CK207_00940	COG4206	TonB-dependent receptor
CK207_00950	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CK207_00990	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CK207_00995	COG5001	Diguanylate cyclase
CK207_00995	COG3300	MHYT domain
CK207_01005	COG3852	Histidine kinase
CK207_01015	COG0174	glutamine synthetase
CK207_01030	COG1490	D-aminoacyl-tRNA deacylase activity
CK207_01035	COG0456	acetyltransferase
CK207_01045	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CK207_01050	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CK207_01055	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CK207_01060	COG3031	protein transport across the cell outer membrane
CK207_01070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CK207_01075	COG1459	type II secretion system
CK207_01080	COG2165	general secretion pathway protein
CK207_01085	COG2165	general secretion pathway protein
CK207_01090	COG2165	general secretion pathway protein
CK207_01095	COG4795	General secretion pathway protein
CK207_01100	COG3156	type II secretion system protein K
CK207_01105	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CK207_01110	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CK207_01120	COG1218	3'(2'),5'-bisphosphate nucleotidase
CK207_01125	COG0494	nUDIX hydrolase
CK207_01130	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CK207_01130	COG0316	Belongs to the HesB IscA family
CK207_01135	COG1040	competence protein
CK207_01140	COG0596	Alpha beta hydrolase
CK207_01150	COG2183	response to ionizing radiation
CK207_01155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CK207_01175	COG0583	DNA-binding transcription factor activity
CK207_01195	COG0745	RESPONSE REGULATOR receiver
CK207_01220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CK207_01225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CK207_01230	COG1758	RNA polymerase activity
CK207_01235	COG0194	GDP metabolic process
CK207_01240	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CK207_01245	COG0248	Ppx GppA phosphatase
CK207_01255	COG3118	belongs to the thioredoxin family
CK207_01260	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CK207_01270	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CK207_01355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK207_01365	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CK207_01370	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CK207_01370	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CK207_01375	COG1072	(Pantothenic acid kinase))
CK207_01400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CK207_01405	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CK207_01410	COG0250	Participates in transcription elongation, termination and antitermination
CK207_01420	COG0081	regulation of translation
CK207_01425	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CK207_01430	COG0222	ribosome binding
CK207_01435	COG0085	RNA polymerase activity
CK207_01440	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CK207_01445	COG3385	transposase activity
CK207_01450	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CK207_01455	COG2816	NAD+ diphosphatase activity
CK207_01475	COG4942	peptidase
CK207_01480	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CK207_01495	COG0471	metal ion transport
CK207_01495	COG0490	domain, Protein
CK207_01505	COG1162	GTPase activity
CK207_01510	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CK207_01565	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CK207_01570	COG0802	atpase or kinase
CK207_01575	COG0860	N-Acetylmuramoyl-L-alanine amidase
CK207_01580	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CK207_01585	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CK207_01590	COG1923	regulation of RNA biosynthetic process
CK207_01595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CK207_01600	COG0330	HflC and HflK could
CK207_01605	COG0330	HflC and HflK could
CK207_01610	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CK207_01625	COG0545	Peptidyl-prolyl cis-trans isomerase
CK207_01630	COG2964	Protein conserved in bacteria
CK207_01635	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CK207_01640	COG2923	Belongs to the DsrF TusC family
CK207_01655	COG0049	tRNA binding
CK207_01660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CK207_01665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CK207_01670	COG0360	Binds together with S18 to 16S ribosomal RNA
CK207_01675	COG2965	DNA replication, synthesis of RNA primer
CK207_01685	COG0359	binds to the 23S rRNA
CK207_01695	COG0305	Participates in initiation and elongation during chromosome replication
CK207_01700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CK207_01705	COG0166	Belongs to the GPI family
CK207_01715	COG0735	belongs to the Fur family
CK207_01720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CK207_01740	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CK207_01745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK207_01750	COG0175	sulfate reduction
CK207_01835	COG0646	methionine synthase
CK207_01835	COG1410	methionine synthase
CK207_01840	COG0527	aspartate kinase activity
CK207_01845	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CK207_01860	COG2239	Acts as a magnesium transporter
CK207_01865	COG2433	Pfam Transposase IS66
CK207_01885	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CK207_01900	COG0629	single-stranded DNA binding
CK207_01905	COG2199	diguanylate cyclase activity
CK207_01905	COG2200	EAL domain
CK207_01930	COG3409	Peptidoglycan-binding domain 1 protein
CK207_01930	COG3267	Type II secretory pathway component ExeA
CK207_01940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CK207_01945	COG1459	type II secretion system
CK207_01990	COG1077	Cell shape determining protein MreB Mrl
CK207_01995	COG1792	Involved in formation and maintenance of cell shape
CK207_02000	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CK207_02005	COG0424	maF-like protein
CK207_02010	COG1530	ribonuclease E activity
CK207_02015	COG3164	Protein of unknown function
CK207_02020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CK207_02025	COG0312	modulator of DNA gyrase
CK207_02030	COG2235	arginine
CK207_02050	COG0589	response to stress
CK207_02080	COG0531	amino acid
CK207_02085	COG3385	transposase activity
CK207_02090	COG0142	geranyltranstransferase activity
CK207_02105	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CK207_02110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CK207_02115	COG2966	Psort location CytoplasmicMembrane, score
CK207_02120	COG3610	response to peptide
CK207_02135	COG2967	ApaG domain
CK207_02145	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CK207_02150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CK207_02155	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CK207_02160	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CK207_02210	COG0741	lytic transglycosylase activity
CK207_02225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CK207_02230	COG2066	Belongs to the glutaminase family
CK207_02235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CK207_02260	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CK207_02265	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CK207_02285	COG1678	Uncharacterized ACR, COG1678
CK207_02295	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CK207_02300	COG2356	endonuclease I
CK207_02305	COG3091	SprT-like family
CK207_02310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CK207_02315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CK207_02320	COG0583	DNA-binding transcription factor activity
CK207_02325	COG4771	TonB-dependent receptor
CK207_02330	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CK207_02335	COG0126	phosphoglycerate kinase activity
CK207_02345	COG0191	fructose-bisphosphate aldolase activity
CK207_02350	COG0668	transmembrane transport
CK207_02370	COG3706	GGDEF domain
CK207_02375	COG3385	transposase activity
CK207_02380	COG0469	pyruvate kinase activity
CK207_02385	COG1349	DNA-binding transcription factor activity
CK207_02410	COG4251	negative regulation of phosphorylation
CK207_02420	COG3335	DDE superfamily endonuclease
CK207_02460	COG2433	Pfam Transposase IS66
CK207_02465	COG4372	Transposase
CK207_02535	COG0583	DNA-binding transcription factor activity
CK207_02540	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CK207_02560	COG3501	Rhs element vgr protein
CK207_02605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CK207_02610	COG0358	DNA primase activity
CK207_02615	COG1610	YqeY-like protein
CK207_02635	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CK207_02640	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CK207_02645	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CK207_02650	COG1968	undecaprenyl-diphosphatase activity
CK207_02655	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CK207_02660	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CK207_02665	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CK207_02670	COG0585	pseudouridine synthase activity
CK207_02675	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CK207_02680	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CK207_02685	COG1388	LysM domain
CK207_02685	COG4942	peptidase
CK207_02695	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CK207_02705	COG4150	thiosulfate binding
CK207_02715	COG4208	sulfate ABC transporter
CK207_02720	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CK207_02725	COG1546	Belongs to the CinA family
CK207_02730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CK207_02735	COG2137	regulation of response to DNA damage stimulus
CK207_02740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CK207_02745	COG0527	aspartate kinase activity
CK207_02795	COG3630	sodium ion export across plasma membrane
CK207_02800	COG5016	pyruvate
CK207_02800	COG0511	ligase activity, forming carbon-carbon bonds
CK207_02805	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CK207_02810	COG1063	alcohol dehydrogenase
CK207_02815	COG1238	metal cluster binding
CK207_02820	COG0612	Peptidase, M16
CK207_02835	COG4536	flavin adenine dinucleotide binding
CK207_02840	COG4137	Cytochrome C assembly protein
CK207_02845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CK207_02865	COG0335	large ribosomal subunit rRNA binding
CK207_02870	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CK207_02875	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CK207_02880	COG0237	dephospho-CoA kinase activity
CK207_02890	COG1459	type II secretion system
CK207_02895	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CK207_02905	COG0157	Belongs to the NadC ModD family
CK207_02915	COG0716	FMN binding
CK207_02920	COG4974	Belongs to the 'phage' integrase family
CK207_02925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CK207_02930	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CK207_02935	COG2186	Transcriptional regulator
CK207_02940	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CK207_02945	COG0508	dehydrogenase complex catalyzes the overall conversion of
CK207_02950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK207_02965	COG0288	reversible hydration of carbon dioxide
CK207_02970	COG0659	secondary active sulfate transmembrane transporter activity
CK207_02975	COG1131	(ABC) transporter
CK207_03020	COG4974	Belongs to the 'phage' integrase family
CK207_03040	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CK207_03050	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CK207_03060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CK207_03065	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CK207_03070	COG1489	DNA binding
CK207_03075	COG1643	Atp-dependent helicase
CK207_03080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CK207_03085	COG1752	Esterase of the alpha-beta hydrolase superfamily
CK207_03090	COG1049	propionate catabolic process, 2-methylcitrate cycle
CK207_03095	COG1929	Belongs to the glycerate kinase type-1 family
CK207_03100	COG2610	gluconate transmembrane transporter activity
CK207_03105	COG3835	regulator
CK207_03120	COG0004	ammonium transporteR
CK207_03125	COG1840	ABC-type Fe3 transport system, periplasmic component
CK207_03140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CK207_03155	COG2971	BadF BadG BcrA BcrD
CK207_03165	COG4608	Belongs to the ABC transporter superfamily
CK207_03170	COG0444	Belongs to the ABC transporter superfamily
CK207_03175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK207_03185	COG0747	negative chemotaxis
CK207_03200	COG0628	permease
CK207_03205	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CK207_03210	COG0316	Belongs to the HesB IscA family
CK207_03225	COG0739	heme binding
CK207_03230	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CK207_03240	COG2239	Acts as a magnesium transporter
CK207_03245	COG2027	D-alanyl-D-alanine carboxypeptidase
CK207_03250	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CK207_03255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CK207_03260	COG1534	Rna-binding protein
CK207_03270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CK207_03275	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CK207_03280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CK207_03285	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CK207_03300	COG0779	Required for maturation of 30S ribosomal subunits
CK207_03305	COG0195	Participates in both transcription termination and antitermination
CK207_03320	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CK207_03340	COG1846	Transcriptional regulator
CK207_03370	COG3153	acetyltransferase
CK207_03395	COG0513	Belongs to the DEAD box helicase family
CK207_03400	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CK207_03415	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CK207_03420	COG2204	response regulator
CK207_03430	COG0667	Aldo Keto reductase
CK207_03435	COG3066	DNA modification
CK207_03440	COG0494	nUDIX hydrolase
CK207_03445	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CK207_03450	COG0730	response to heat
CK207_03465	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CK207_03490	COG3550	peptidyl-serine autophosphorylation
CK207_03530	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CK207_03550	COG2433	Pfam Transposase IS66
CK207_03565	COG2433	Pfam Transposase IS66
CK207_03585	COG4974	Belongs to the 'phage' integrase family
CK207_03595	COG1283	sodium-dependent phosphate transmembrane transporter activity
CK207_03600	COG0583	DNA-binding transcription factor activity
CK207_03605	COG0640	Transcriptional regulator
CK207_03615	COG0728	peptidoglycan biosynthetic process
CK207_03620	COG0196	riboflavin kinase activity
CK207_03630	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CK207_03635	COG1047	Peptidyl-prolyl cis-trans
CK207_03645	COG1966	Carbon starvation protein
CK207_03660	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CK207_03665	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CK207_03670	COG1472	Belongs to the glycosyl hydrolase 3 family
CK207_03675	COG3279	Response regulator of the LytR AlgR family
CK207_03680	COG3275	phosphorelay sensor kinase activity
CK207_03685	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CK207_03690	COG1605	Chorismate mutase
CK207_03690	COG0287	Prephenate dehydrogenase
CK207_03700	COG0488	(ABC) transporter
CK207_03715	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CK207_03720	COG5001	Diguanylate cyclase
CK207_03725	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CK207_03730	COG1605	Chorismate mutase
CK207_03730	COG0077	Prephenate dehydratase
CK207_03735	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CK207_03740	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CK207_03745	COG0564	pseudouridine synthase activity
CK207_03755	COG0542	response to heat
CK207_03795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CK207_03810	COG0745	RESPONSE REGULATOR receiver
CK207_03815	COG5002	protein histidine kinase activity
CK207_03825	COG0248	Ppx GppA phosphatase
CK207_03830	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CK207_03840	COG0581	inorganic phosphate transmembrane transporter activity
CK207_03845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CK207_03850	COG0704	Plays a role in the regulation of phosphate uptake
CK207_03855	COG3142	Participates in the control of copper homeostasis
CK207_03860	COG0450	alkyl hydroperoxide reductase
CK207_03865	COG0583	DNA-binding transcription factor activity
CK207_03870	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CK207_03880	COG0517	IMP dehydrogenase activity
CK207_03885	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CK207_03895	COG1862	Preprotein translocase
CK207_03900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK207_03905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK207_03910	COG0483	inositol monophosphate 1-phosphatase activity
CK207_03915	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CK207_03920	COG1959	2 iron, 2 sulfur cluster binding
CK207_03930	COG0822	iron-sulfur transferase activity
CK207_03935	COG0316	Belongs to the HesB IscA family
CK207_03945	COG0443	Heat shock 70 kDa protein
CK207_03950	COG0633	Ferredoxin
CK207_03955	COG2975	iron-sulfur cluster assembly
CK207_03960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CK207_03975	COG1426	Protein conserved in bacteria
CK207_03980	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CK207_03985	COG0124	histidyl-tRNA synthetase
CK207_03990	COG2976	Protein conserved in bacteria
CK207_03995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CK207_04000	COG1160	GTP binding
CK207_04020	COG0517	IMP dehydrogenase activity
CK207_04020	COG0516	GMP reductase activity
CK207_04025	COG0519	Catalyzes the synthesis of GMP from XMP
CK207_04025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CK207_04030	COG0351	phosphomethylpyrimidine kinase
CK207_04040	COG1584	GPR1 FUN34 yaaH family protein
CK207_04045	COG1115	amino acid carrier protein
CK207_04050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK207_04065	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CK207_04070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_04070	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_04085	COG3964	amidohydrolase
CK207_04150	COG2433	Pfam Transposase IS66
CK207_04210	COG2003	Belongs to the UPF0758 family
CK207_04255	COG2433	Pfam Transposase IS66
CK207_04310	COG2003	Belongs to the UPF0758 family
CK207_04320	COG4409	exo-alpha-(2->6)-sialidase activity
CK207_04325	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CK207_04330	COG1940	carbohydrate kinase activity
CK207_04335	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CK207_04345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CK207_04350	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CK207_04355	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CK207_04360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CK207_04365	COG1737	Transcriptional regulator
CK207_04370	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CK207_04375	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CK207_04390	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_04395	COG3716	PTS system mannose fructose sorbose family IID component
CK207_04400	COG3715	PTS system
CK207_04405	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK207_04410	COG2222	sugar isomerase
CK207_04420	COG1349	DNA-binding transcription factor activity
CK207_04425	COG1349	DNA-binding transcription factor activity
CK207_04440	COG2003	Belongs to the UPF0758 family
CK207_04490	COG1715	Restriction endonuclease
CK207_04495	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CK207_04500	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CK207_04505	COG0732	type I restriction modification DNA specificity domain
CK207_04510	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CK207_04530	COG2433	Pfam Transposase IS66
CK207_04555	COG2433	Pfam Transposase IS66
CK207_04575	COG2867	negative regulation of translational initiation
CK207_04580	COG2914	Belongs to the UPF0125 (RnfH) family
CK207_04585	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CK207_04590	COG0497	DNA recombination
CK207_04600	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CK207_04605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CK207_04610	COG0443	Heat shock 70 kDa protein
CK207_04615	COG0484	heat shock protein binding
CK207_04650	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CK207_04660	COG0583	DNA-binding transcription factor activity
CK207_04665	COG0590	tRNA wobble adenosine to inosine editing
CK207_04670	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CK207_04695	COG2979	Protein of unknown function (DUF533)
CK207_04700	COG0442	prolyl-tRNA aminoacylation
CK207_04705	COG1720	tRNA m6t6A37 methyltransferase activity
CK207_04715	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CK207_04745	COG3098	single-species biofilm formation
CK207_04750	COG0564	pseudouridine synthase activity
CK207_04755	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CK207_04760	COG0142	geranyltranstransferase activity
CK207_04770	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CK207_04780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CK207_04780	COG0301	tRNA thio-modification
CK207_04785	COG0583	DNA-binding transcription factor activity
CK207_04790	COG2363	Small membrane protein
CK207_04800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CK207_04805	COG1611	Belongs to the LOG family
CK207_04810	COG3706	GGDEF domain
CK207_04830	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CK207_04835	COG1464	Belongs to the NlpA lipoprotein family
CK207_04840	COG2011	ABC-type metal ion transport system permease component
CK207_04845	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CK207_04850	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CK207_04865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK207_04865	COG1263	PTS System
CK207_04870	COG0366	Alpha amylase catalytic
CK207_04875	COG0745	RESPONSE REGULATOR receiver
CK207_04880	COG2205	protein histidine kinase activity
CK207_04915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK207_04920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK207_04925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CK207_04930	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CK207_04935	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CK207_04950	COG1215	transferase activity, transferring glycosyl groups
CK207_04955	COG0438	transferase activity, transferring glycosyl groups
CK207_04975	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CK207_05010	COG0489	protein tyrosine kinase activity
CK207_05015	COG1596	polysaccharide export
CK207_05035	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CK207_05050	COG0321	lipoyl(octanoyl) transferase activity
CK207_05055	COG2921	Belongs to the UPF0250 family
CK207_05060	COG1686	Belongs to the peptidase S11 family
CK207_05065	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CK207_05070	COG0772	Belongs to the SEDS family
CK207_05075	COG0768	penicillin binding
CK207_05080	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CK207_05085	COG0799	negative regulation of ribosome biogenesis
CK207_05090	COG1466	dna polymerase III delta subunit
CK207_05095	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CK207_05100	COG0495	leucyl-tRNA aminoacylation
CK207_05105	COG2888	peptidyl-tyrosine sulfation
CK207_05110	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CK207_05115	COG4535	Mg2 and Co2 transporter CorC
CK207_05125	COG1702	phosphate starvation-inducible protein PhoH
CK207_05130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CK207_05135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK207_05140	COG2190	(PTS) system
CK207_05145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CK207_05150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_05155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CK207_05160	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CK207_05165	COG3115	cell septum assembly
CK207_05185	COG3335	DDE superfamily endonuclease
CK207_05190	COG0789	Transcriptional regulator
CK207_05200	COG0330	HflC and HflK could
CK207_05205	COG3118	belongs to the thioredoxin family
CK207_05210	COG1090	epimerase
CK207_05215	COG0622	Phosphoesterase
CK207_05230	COG3710	Transcriptional regulator
CK207_05235	COG0326	Molecular chaperone. Has ATPase activity
CK207_05245	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CK207_05255	COG2433	Pfam Transposase IS66
CK207_05275	COG3385	transposase activity
CK207_05285	COG0367	asparagine synthase
CK207_05290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CK207_05290	COG4651	solute:proton antiporter activity
CK207_05295	COG1846	Transcriptional regulator
CK207_05295	COG1940	carbohydrate kinase activity
CK207_05300	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CK207_05305	COG2190	(PTS) system
CK207_05305	COG1263	PTS System
CK207_05305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK207_05310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CK207_05330	COG0285	dihydrofolate synthase activity
CK207_05335	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CK207_05340	COG1286	toxin biosynthetic process
CK207_05345	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CK207_05350	COG2056	Na+-H+ antiporter family
CK207_05355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CK207_05365	COG0346	lactoylglutathione lyase activity
CK207_05400	COG1132	(ABC) transporter
CK207_05440	COG2433	Pfam Transposase IS66
CK207_05475	COG2433	Pfam Transposase IS66
CK207_05495	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CK207_05510	COG4658	electron transport chain
CK207_05515	COG4656	Part of a membrane complex involved in electron transport
CK207_05520	COG2878	Part of a membrane complex involved in electron transport
CK207_05525	COG4657	Part of a membrane complex involved in electron transport
CK207_05535	COG4774	siderophore transport
CK207_05535	COG1629	transport
CK207_05540	COG2382	esterase
CK207_05560	COG1535	isochorismatase
CK207_05560	COG3433	isochorismatase activity
CK207_05565	COG1021	2,3-dihydroxybenzoate-AMP ligase
CK207_05570	COG1169	isochorismate synthase
CK207_05575	COG1028	Short-chain dehydrogenase reductase Sdr
CK207_05580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CK207_05590	COG4771	TonB-dependent receptor
CK207_05605	COG0583	DNA-binding transcription factor activity
CK207_05615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK207_05620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK207_05625	COG1902	pentaerythritol trinitrate reductase activity
CK207_05635	COG2814	Major facilitator Superfamily
CK207_05640	COG1028	Short-chain dehydrogenase reductase Sdr
CK207_05655	COG0556	nucleotide-excision repair
CK207_05660	COG2204	response regulator
CK207_05665	COG2198	Histidine kinase
CK207_05670	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CK207_05675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CK207_05680	COG0521	Mo-molybdopterin cofactor biosynthetic process
CK207_05690	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CK207_05695	COG0314	molybdopterin synthase activity
CK207_05700	COG2199	diguanylate cyclase activity
CK207_05705	COG4109	DRTGG domain
CK207_05710	COG3335	DDE superfamily endonuclease
CK207_05720	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CK207_05730	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK207_05730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK207_05735	COG0489	protein tyrosine kinase activity
CK207_05740	COG0572	uridine kinase
CK207_05745	COG2982	Protein involved in outer membrane biogenesis
CK207_05750	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CK207_05755	COG2067	long-chain fatty acid transport protein
CK207_05760	COG2067	long-chain fatty acid transport protein
CK207_05770	COG1595	DNA-templated transcription, initiation
CK207_05780	COG0183	Belongs to the thiolase family
CK207_05785	COG1024	Enoyl-CoA hydratase
CK207_05785	COG1250	3-hydroxyacyl-CoA dehydrogenase
CK207_05790	COG0778	Nitroreductase
CK207_05795	COG0583	DNA-binding transcription factor activity
CK207_05800	COG0745	RESPONSE REGULATOR receiver
CK207_05810	COG2832	Protein of unknown function (DUF454)
CK207_05815	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CK207_05825	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CK207_05890	COG2433	Pfam Transposase IS66
CK207_05925	COG2226	methyltransferase
CK207_05940	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CK207_05950	COG3139	Protein of unknown function (DUF1315)
CK207_05955	COG0252	asparaginase activity
CK207_05960	COG0616	signal peptide processing
CK207_05965	COG1902	pentaerythritol trinitrate reductase activity
CK207_05965	COG0446	pyridine nucleotide-disulphide oxidoreductase
CK207_05970	COG0788	formyltetrahydrofolate deformylase activity
CK207_05980	COG1199	ATP-dependent helicase activity
CK207_05985	COG1214	PFAM Peptidase M22, glycoprotease
CK207_06000	COG0596	Alpha beta hydrolase
CK207_06005	COG0318	PFAM AMP-dependent synthetase and ligase
CK207_06010	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CK207_06020	COG3385	transposase activity
CK207_06030	COG2894	cell division
CK207_06040	COG3100	YcgL domain-containing protein
CK207_06045	COG2951	lytic endotransglycosylase activity
CK207_06050	COG0583	DNA-binding transcription factor activity
CK207_06055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK207_06080	COG4628	conserved protein (DUF2132)
CK207_06095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK207_06105	COG0513	Belongs to the DEAD box helicase family
CK207_06115	COG1760	l-serine dehydratase
CK207_06120	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CK207_06125	COG0745	RESPONSE REGULATOR receiver
CK207_06130	COG2205	protein histidine kinase activity
CK207_06135	COG1653	transport
CK207_06145	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CK207_06150	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CK207_06155	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CK207_06175	COG0544	peptidyl-prolyl cis-trans isomerase activity
CK207_06190	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CK207_06195	COG0776	regulation of translation
CK207_06200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CK207_06205	COG1555	photosystem II stabilization
CK207_06210	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CK207_06215	COG0539	negative regulation of cytoplasmic translation
CK207_06225	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CK207_06230	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CK207_06245	COG0583	DNA-binding transcription factor activity
CK207_06255	COG0686	Belongs to the AlaDH PNT family
CK207_06260	COG1522	sequence-specific DNA binding
CK207_06265	COG1674	ftsk spoiiie
CK207_06275	COG0501	Belongs to the peptidase M48B family
CK207_06285	COG0300	oxidoreductase activity
CK207_06300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CK207_06310	COG2268	Band 7 protein
CK207_06320	COG1032	radical SAM domain protein
CK207_06345	COG0583	DNA-binding transcription factor activity
CK207_06350	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CK207_06360	COG2350	Protein conserved in bacteria
CK207_06365	COG1607	acyl-coa hydrolase
CK207_06395	COG0133	tryptophan synthase activity
CK207_06400	COG0134	indole-3-glycerol-phosphate synthase activity
CK207_06400	COG0135	phosphoribosylanthranilate isomerase activity
CK207_06405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CK207_06410	COG0512	Glutamine amidotransferase of anthranilate synthase
CK207_06415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CK207_06425	COG0613	PHP domain protein
CK207_06430	COG0009	L-threonylcarbamoyladenylate synthase
CK207_06435	COG1187	pseudouridine synthase activity
CK207_06440	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CK207_06445	COG4988	ABC transporter
CK207_06450	COG0492	ferredoxin-NADP+ reductase activity
CK207_06455	COG0745	RESPONSE REGULATOR receiver
CK207_06455	COG3706	GGDEF domain
CK207_06470	COG2949	membrane
CK207_06480	COG0281	malic enzyme
CK207_06500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CK207_06510	COG1737	Transcriptional regulator
CK207_06515	COG0076	glutamate decarboxylase activity
CK207_06525	COG2431	L-lysine efflux transmembrane transporter activity
CK207_06535	COG3070	regulator of competence-specific genes
CK207_06550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK207_06550	COG4191	Histidine kinase
CK207_06560	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CK207_06565	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CK207_06570	COG2915	High frequency lysogenization protein hflD homolog
CK207_06575	COG0482	sulfurtransferase activity
CK207_06585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK207_06590	COG2916	Histone family protein nucleoid-structuring protein H-NS
CK207_06595	COG1757	Na H antiporter
CK207_06605	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CK207_06610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CK207_06615	COG0131	Imidazoleglycerol-phosphate dehydratase
CK207_06615	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CK207_06620	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CK207_06625	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CK207_06630	COG0107	imidazoleglycerol-phosphate synthase activity
CK207_06635	COG0140	phosphoribosyl-ATP diphosphatase activity
CK207_06635	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CK207_06640	COG1187	pseudouridine synthase activity
CK207_06650	COG1278	Cold shock
CK207_06655	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CK207_06660	COG0542	response to heat
CK207_06665	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CK207_06670	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CK207_06675	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CK207_06680	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CK207_06690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CK207_06700	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CK207_06705	COG0297	glycogen (starch) synthase activity
CK207_06725	COG3070	regulator of competence-specific genes
CK207_06730	COG1609	Transcriptional regulator
CK207_06740	COG0745	RESPONSE REGULATOR receiver
CK207_06745	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CK207_06750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CK207_06760	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CK207_06765	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CK207_06780	COG4067	protein conserved in archaea
CK207_06780	COG0189	ligase activity
CK207_06785	COG0500	methyltransferase
CK207_06795	COG1801	Protein of unknown function DUF72
CK207_06800	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CK207_06805	COG1435	thymidine kinase activity
CK207_06815	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CK207_06840	COG2116	formate transmembrane transporter activity
CK207_06845	COG4459	periplasmic nitrate reductase
CK207_06850	COG3005	denitrification pathway
CK207_06855	COG0243	molybdopterin cofactor binding
CK207_06865	COG1227	inorganic diphosphatase activity
CK207_06895	COG0515	serine threonine protein kinase
CK207_06895	COG2815	serine threonine protein kinase
CK207_06910	COG2433	Pfam Transposase IS66
CK207_06915	COG4974	Belongs to the 'phage' integrase family
CK207_06940	COG3344	reverse transcriptase
CK207_06950	COG2433	Pfam Transposase IS66
CK207_06970	COG4172	Belongs to the ABC transporter superfamily
CK207_06980	COG4171	peptide transport system, permease
CK207_06985	COG4168	peptide transport system, permease
CK207_06995	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CK207_07000	COG1842	Phage shock protein A
CK207_07015	COG0519	Catalyzes the synthesis of GMP from XMP
CK207_07020	COG0626	cystathionine gamma-synthase activity
CK207_07030	COG0733	neurotransmitter:sodium symporter activity
CK207_07035	COG0564	pseudouridine synthase activity
CK207_07050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CK207_07055	COG4136	ATPase activity
CK207_07060	COG4135	transport system, permease component
CK207_07065	COG4134	Bacterial extracellular solute-binding protein
CK207_07075	COG3313	Fe-S protein
CK207_07085	COG0737	Belongs to the 5'-nucleotidase family
CK207_07095	COG0513	Belongs to the DEAD box helicase family
CK207_07115	COG2205	protein histidine kinase activity
CK207_07130	COG1061	Type III restriction enzyme res subunit
CK207_07135	COG1187	pseudouridine synthase activity
CK207_07140	COG2814	Major facilitator Superfamily
CK207_07150	COG0702	epimerase
CK207_07155	COG0534	Mate efflux family protein
CK207_07160	COG4181	ATPase activity
CK207_07175	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CK207_07195	COG0019	diaminopimelate decarboxylase activity
CK207_07200	COG0840	transmembrane signaling receptor activity
CK207_07230	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CK207_07235	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CK207_07240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CK207_07250	COG0840	transmembrane signaling receptor activity
CK207_07265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK207_07265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK207_07265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_07270	COG2207	Transcriptional regulator
CK207_07280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK207_07290	COG1342	Belongs to the UPF0251 family
CK207_07310	COG1129	ABC transporter
CK207_07320	COG0583	DNA-binding transcription factor activity
CK207_07325	COG3335	DDE superfamily endonuclease
CK207_07330	COG1902	pentaerythritol trinitrate reductase activity
CK207_07335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CK207_07340	COG5002	protein histidine kinase activity
CK207_07345	COG0745	RESPONSE REGULATOR receiver
CK207_07375	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CK207_07380	COG0372	Belongs to the citrate synthase family
CK207_07385	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CK207_07390	COG2828	Protein conserved in bacteria
CK207_07410	COG0561	phosphatase activity
CK207_07415	COG0602	queuosine metabolic process
CK207_07445	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CK207_07450	COG1254	Belongs to the acylphosphatase family
CK207_07455	COG3328	transposase activity
CK207_07460	COG2920	part of a sulfur-relay system
CK207_07465	COG0670	Belongs to the BI1 family
CK207_07470	COG1126	abc transporter atp-binding protein
CK207_07475	COG0765	amino acid transport
CK207_07480	COG4597	amino acid ABC transporter
CK207_07485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK207_07490	COG1648	precorrin-2 dehydrogenase activity
CK207_07490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CK207_07500	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CK207_07505	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CK207_07505	COG0574	Belongs to the PEP-utilizing enzyme family
CK207_07520	COG2996	Protein conserved in bacteria
CK207_07530	COG3008	intermembrane lipid transfer
CK207_07535	COG2995	paraquat-inducible protein a
CK207_07540	COG1132	(ABC) transporter
CK207_07545	COG1956	GAF domain-containing protein
CK207_07565	COG0308	aminopeptidase N
CK207_07575	COG2902	Dehydrogenase
CK207_07580	COG0167	dihydroorotate dehydrogenase activity
CK207_07590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CK207_07590	COG0116	Belongs to the methyltransferase superfamily
CK207_07615	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CK207_07620	COG1067	ATP-dependent peptidase activity
CK207_07625	COG3120	sequence-specific DNA binding
CK207_07655	COG2433	Pfam Transposase IS66
CK207_07725	COG0270	DNA (cytosine-5-)-methyltransferase activity
CK207_07780	COG3278	Belongs to the heme-copper respiratory oxidase family
CK207_07795	COG2010	Cytochrome c
CK207_07805	COG2217	Heavy metal translocating P-type atpase
CK207_07820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CK207_07825	COG0589	response to stress
CK207_07830	COG2433	Pfam Transposase IS66
CK207_07865	COG3842	ATPase activity
CK207_07870	COG1176	ABC-type spermidine putrescine transport system, permease component I
CK207_07875	COG1177	transmembrane transport
CK207_07880	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CK207_07885	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CK207_07890	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CK207_07895	COG0004	ammonium transporteR
CK207_07900	COG0488	(ABC) transporter
CK207_07915	COG2271	Major facilitator Superfamily
CK207_07920	COG1840	ABC-type Fe3 transport system, periplasmic component
CK207_07930	COG3842	ATPase activity
CK207_07935	COG0746	molybdenum cofactor guanylyltransferase activity
CK207_07940	COG1763	Mo-molybdopterin cofactor biosynthetic process
CK207_07965	COG0840	transmembrane signaling receptor activity
CK207_07970	COG0791	NLP P60 protein
CK207_07995	COG1793	dna ligase
CK207_08000	COG4667	esterase of the alpha-beta hydrolase superfamily
CK207_08015	COG0848	biopolymer transport protein
CK207_08020	COG0811	peptide transport
CK207_08025	COG0811	peptide transport
CK207_08055	COG0625	glutathione transferase activity
CK207_08065	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CK207_08085	COG1115	amino acid carrier protein
CK207_08090	COG1280	lysine exporter protein (LysE YggA)
CK207_08095	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CK207_08100	COG0477	Major facilitator Superfamily
CK207_08115	COG1643	Atp-dependent helicase
CK207_08155	COG0443	Heat shock 70 kDa protein
CK207_08185	COG1609	Transcriptional regulator
CK207_08190	COG2723	6-phospho-beta-galactosidase activity
CK207_08195	COG0513	Belongs to the DEAD box helicase family
CK207_08200	COG0243	molybdopterin cofactor binding
CK207_08205	COG3005	denitrification pathway
CK207_08210	COG1278	Cold shock
CK207_08225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK207_08225	COG4191	Histidine kinase
CK207_08250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CK207_08260	COG3706	GGDEF domain
CK207_08270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK207_08280	COG3768	UPF0283 membrane protein
CK207_08285	COG3106	COG3106 Predicted ATPase
CK207_08300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CK207_08305	COG0494	nUDIX hydrolase
CK207_08340	COG0814	amino acid
CK207_08345	COG1760	l-serine dehydratase
CK207_08355	COG2356	endonuclease I
CK207_08360	COG0720	synthase
CK207_08365	COG0840	transmembrane signaling receptor activity
CK207_08370	COG0017	Asparaginyl-tRNA synthetase
CK207_08380	COG2201	protein-glutamate methylesterase activity
CK207_08385	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CK207_08390	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CK207_08395	COG0835	chemotaxis
CK207_08405	COG2198	Histidine kinase
CK207_08405	COG0643	Histidine kinase
CK207_08415	COG0745	RESPONSE REGULATOR receiver
CK207_08420	COG0840	transmembrane signaling receptor activity
CK207_08425	COG3437	response regulator, receiver
CK207_08425	COG2770	Histidine kinase
CK207_08430	COG1448	Aminotransferase
CK207_08435	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CK207_08450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK207_08455	COG1846	Transcriptional regulator
CK207_08470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK207_08475	COG3108	Peptidase M15
CK207_08480	COG2989	Protein conserved in bacteria
CK207_08510	COG1940	carbohydrate kinase activity
CK207_08520	COG0748	coenzyme F420 binding
CK207_08525	COG3721	Heme iron utilization protein
CK207_08530	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CK207_08535	COG0811	peptide transport
CK207_08540	COG0848	biopolymer transport protein
CK207_08550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK207_08555	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CK207_08570	COG0840	transmembrane signaling receptor activity
CK207_08575	COG1621	beta-fructofuranosidase activity
CK207_08585	COG1263	PTS System
CK207_08585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK207_08590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK207_08595	COG2200	EAL domain
CK207_08600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CK207_08605	COG3335	DDE superfamily endonuclease
CK207_08675	COG0515	serine threonine protein kinase
CK207_08675	COG3064	Membrane
CK207_08675	COG4991	sh3 domain protein
CK207_08700	COG1716	ATPase activity
CK207_08720	COG1181	Belongs to the D-alanine--D-alanine ligase family
CK207_08770	COG3501	Rhs element vgr protein
CK207_08795	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CK207_08820	COG3706	GGDEF domain
CK207_08820	COG0745	RESPONSE REGULATOR receiver
CK207_08840	COG0835	chemotaxis
CK207_08840	COG0784	Response regulator, receiver
CK207_08850	COG4565	transcriptional regulatory protein
CK207_08855	COG3290	protein histidine kinase activity
CK207_08870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK207_08895	COG3063	Type IV pilus biogenesis stability protein PilW
CK207_08910	COG1451	nucleotide metabolic process
CK207_08920	COG0583	DNA-binding transcription factor activity
CK207_08945	COG4139	cobalamin transport
CK207_08950	COG2988	succinylglutamate desuccinylase activity
CK207_08965	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CK207_08975	COG1073	alpha beta
CK207_08975	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CK207_08975	COG3064	Membrane
CK207_08980	COG2994	toxin metabolic process
CK207_09010	COG0702	epimerase
CK207_09020	COG2925	Exonuclease
CK207_09030	COG1346	cytolysis
CK207_09035	COG0295	cytidine deaminase activity
CK207_09040	COG3300	MHYT domain
CK207_09040	COG5001	Diguanylate cyclase
CK207_09045	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CK207_09070	COG0072	phenylalanine-tRNA ligase activity
CK207_09070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK207_09115	COG0322	excinuclease ABC activity
CK207_09120	COG2197	response regulator
CK207_09125	COG0417	DNA replication proofreading
CK207_09135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CK207_09140	COG3099	Belongs to the UPF0263 family
CK207_09150	COG2188	Transcriptional regulator
CK207_09155	COG1228	amidohydrolase
CK207_09160	COG0010	Belongs to the arginase family
CK207_09170	COG2986	histidine ammonia-lyase
CK207_09185	COG0247	lactate metabolic process
CK207_09185	COG0277	FAD linked oxidase domain protein
CK207_09215	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CK207_09220	COG1960	acyl-CoA dehydrogenase activity
CK207_09265	COG5002	protein histidine kinase activity
CK207_09265	COG0784	Response regulator, receiver
CK207_09280	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CK207_09285	COG2885	chlorophyll binding
CK207_09305	COG0811	peptide transport
CK207_09310	COG0824	Thioesterase
CK207_09315	COG3790	cyd operon protein YbgE
CK207_09320	COG4890	Cyd operon protein YbgT
CK207_09325	COG1294	oxidase, subunit
CK207_09330	COG1271	oxidase subunit
CK207_09335	COG2255	four-way junction helicase activity
CK207_09340	COG0632	four-way junction helicase activity
CK207_09345	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CK207_09350	COG0215	cysteine-tRNA ligase activity
CK207_09355	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CK207_09360	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CK207_09365	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CK207_09370	COG3012	SEC-C Motif Domain Protein
CK207_09385	COG1199	ATP-dependent helicase activity
CK207_09395	COG3923	Primosomal replication protein n
CK207_09405	COG0840	transmembrane signaling receptor activity
CK207_09435	COG2433	Pfam Transposase IS66
CK207_09455	COG0708	Exodeoxyribonuclease III
CK207_09460	COG4160	amino acid transport
CK207_09465	COG4215	(ABC) transporter
CK207_09490	COG1882	Formate acetyltransferase
CK207_09505	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CK207_09520	COG2766	serine protein kinase
CK207_09525	COG2718	Belongs to the UPF0229 family
CK207_09530	COG2719	SpoVR family
CK207_09535	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CK207_09550	COG1132	(ABC) transporter
CK207_09555	COG2333	competence protein COMEC
CK207_09555	COG0658	competence protein
CK207_09565	COG4591	ABC-type transport system involved in lipoprotein release permease component
CK207_09570	COG1136	(ABC) transporter
CK207_09575	COG4591	ABC-type transport system involved in lipoprotein release permease component
CK207_09585	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CK207_09600	COG1252	NADH dehydrogenase
CK207_09630	COG0537	adenosine 5'-monophosphoramidase activity
CK207_09645	COG2186	Transcriptional regulator
CK207_09650	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CK207_09660	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CK207_09665	COG2226	methyltransferase
CK207_09680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CK207_09690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CK207_09695	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CK207_09705	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CK207_09715	COG4120	Belongs to the binding-protein-dependent transport system permease family
CK207_09725	COG3092	negative regulation of chromosome organization
CK207_09730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CK207_09735	COG0280	phosphate acetyltransferase
CK207_09735	COG0857	belongs to the CobB CobQ family
CK207_09740	COG0435	Glutathione S-transferase
CK207_09750	COG0444	Belongs to the ABC transporter superfamily
CK207_09755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK207_09760	COG0601	transmembrane transport
CK207_09775	COG5002	protein histidine kinase activity
CK207_09775	COG0784	Response regulator, receiver
CK207_09800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK207_09805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK207_09825	COG1216	Glycosyl transferase, family 2
CK207_09855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CK207_09865	COG1028	Short-chain dehydrogenase reductase Sdr
CK207_09920	COG0800	Aldolase
CK207_09925	COG2610	gluconate transmembrane transporter activity
CK207_09930	COG3265	gluconokinase activity
CK207_09935	COG0129	dihydroxy-acid dehydratase activity
CK207_09940	COG1609	Transcriptional regulator
CK207_09955	COG3850	Histidine kinase
CK207_09955	COG5002	protein histidine kinase activity
CK207_09965	COG2985	domain, Protein
CK207_09995	COG2433	Pfam Transposase IS66
CK207_10005	COG0642	Histidine kinase
CK207_10010	COG0745	RESPONSE REGULATOR receiver
CK207_10020	COG0300	oxidoreductase activity
CK207_10030	COG1022	Amp-dependent synthetase and ligase
CK207_10040	COG3335	DDE superfamily endonuclease
CK207_10060	COG1061	Type III restriction enzyme res subunit
CK207_10080	COG3335	DDE superfamily endonuclease
CK207_10105	COG3706	GGDEF domain
CK207_10120	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CK207_10125	COG1946	Acyl-CoA thioesterase
CK207_10130	COG1522	sequence-specific DNA binding
CK207_10165	COG0318	PFAM AMP-dependent synthetase and ligase
CK207_10170	COG1441	menaquinone biosynthetic process
CK207_10175	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CK207_10185	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CK207_10190	COG1169	isochorismate synthase
CK207_10200	COG0436	Aminotransferase
CK207_10205	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CK207_10210	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CK207_10225	COG0616	signal peptide processing
CK207_10230	COG1028	Short-chain dehydrogenase reductase Sdr
CK207_10235	COG0835	chemotaxis
CK207_10235	COG0784	Response regulator, receiver
CK207_10240	COG1940	carbohydrate kinase activity
CK207_10250	COG4667	esterase of the alpha-beta hydrolase superfamily
CK207_10265	COG0733	neurotransmitter:sodium symporter activity
CK207_10275	COG1263	PTS System
CK207_10275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK207_10280	COG0084	hydrolase, TatD family'
CK207_10285	COG0470	DNA polymerase III
CK207_10290	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CK207_10295	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CK207_10300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CK207_10325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CK207_10335	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CK207_10340	COG1399	metal-binding, possibly nucleic acid-binding protein
CK207_10345	COG0424	maF-like protein
CK207_10350	COG0564	pseudouridine synthase activity
CK207_10355	COG1530	ribonuclease E activity
CK207_10365	COG1012	belongs to the aldehyde dehydrogenase family
CK207_10365	COG1454	alcohol dehydrogenase
CK207_10370	COG2095	MarC family integral membrane protein
CK207_10375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CK207_10380	COG1757	Na H antiporter
CK207_10385	COG3385	transposase activity
CK207_10400	COG3082	Protein of unknown function (DUF1414)
CK207_10405	COG3083	sulfuric ester hydrolase activity
CK207_10415	COG0243	molybdopterin cofactor binding
CK207_10420	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CK207_10475	COG3501	Rhs element vgr protein
CK207_10505	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CK207_10515	COG1196	nuclear chromosome segregation
CK207_10520	COG0732	type I restriction modification DNA specificity domain
CK207_10570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CK207_10575	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CK207_10595	COG2853	Lipoprotein
CK207_10610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CK207_10615	COG1138	Cytochrome C-type biogenesis protein
CK207_10620	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CK207_10630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CK207_10635	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CK207_10640	COG4133	protoheme IX ABC transporter activity
CK207_10650	COG0835	chemotaxis
CK207_10660	COG1192	Involved in chromosome partitioning
CK207_10665	COG2201	protein-glutamate methylesterase activity
CK207_10670	COG2198	Histidine kinase
CK207_10670	COG0643	Histidine kinase
CK207_10675	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CK207_10690	COG0455	bacterial-type flagellum organization
CK207_10700	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CK207_10705	COG2062	phosphohistidine phosphatase, SixA
CK207_10710	COG1025	Belongs to the peptidase M16 family
CK207_10715	COG3102	Protein conserved in bacteria
CK207_10740	COG1918	ferrous iron import across plasma membrane
CK207_10745	COG4977	sequence-specific DNA binding
CK207_10750	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CK207_10755	COG1121	(ABC) transporter
CK207_10760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CK207_10775	COG0508	dehydrogenase complex catalyzes the overall conversion of
CK207_10780	COG0567	Dehydrogenase, E1 component
CK207_10795	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CK207_10800	COG2009	succinate dehydrogenase
CK207_10810	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CK207_10820	COG0033	Phosphoglucomutase
CK207_10825	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CK207_10830	COG0596	Alpha beta hydrolase
CK207_10840	COG0716	FMN binding
CK207_10845	COG1346	cytolysis
CK207_10855	COG0583	DNA-binding transcription factor activity
CK207_10865	COG0735	belongs to the Fur family
CK207_10870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CK207_10875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CK207_10880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CK207_10885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK207_10885	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CK207_10890	COG0431	NADPH-dependent FMN reductase
CK207_10900	COG3101	peptidyl-lysine hydroxylation
CK207_10905	COG2860	membrane
CK207_10910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CK207_10915	COG2890	protein-(glutamine-N5) methyltransferase activity
CK207_10920	COG2840	Smr protein MutS2
CK207_10930	COG1684	flagellar biosynthetic protein fliR
CK207_10935	COG1987	bacterial-type flagellum assembly
CK207_10985	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CK207_10995	COG1677	Flagellar hook-basal body complex protein FliE
CK207_11000	COG2204	response regulator
CK207_11005	COG4191	Histidine kinase
CK207_11010	COG2204	response regulator
CK207_11015	COG1516	flagellar protein fliS
CK207_11025	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CK207_11050	COG2837	iron assimilation
CK207_11075	COG1393	Belongs to the ArsC family
CK207_11080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CK207_11100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CK207_11120	COG2433	Pfam Transposase IS66
CK207_11155	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CK207_11180	COG2433	Pfam Transposase IS66
CK207_11215	COG2433	Pfam Transposase IS66
CK207_11220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK207_11220	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CK207_11225	COG3550	peptidyl-serine autophosphorylation
CK207_11260	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CK207_11280	COG4783	chaperone-mediated protein folding
CK207_11285	COG1393	Belongs to the ArsC family
CK207_11305	COG2233	PERMEase
CK207_11310	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CK207_11320	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CK207_11325	COG2912	Transglutaminase-like superfamily
CK207_11330	COG3094	Invasion gene expression up-regulator, SirB
CK207_11335	COG2890	protein-(glutamine-N5) methyltransferase activity
CK207_11340	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CK207_11345	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CK207_11350	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CK207_11365	COG0193	aminoacyl-tRNA hydrolase activity
CK207_11470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CK207_11480	COG1705	Flagellar rod assembly protein muramidase FlgJ
CK207_11480	COG3951	Flagellar rod assembly protein muramidase FlgJ
CK207_11485	COG1706	bacterial-type flagellum-dependent cell motility
CK207_11490	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CK207_11495	COG4786	Flagellar basal body rod
CK207_11500	COG4787	bacterial-type flagellum-dependent cell motility
CK207_11505	COG1749	Flagellar hook protein flgE
CK207_11510	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CK207_11515	COG1558	bacterial-type flagellum-dependent cell motility
CK207_11520	COG1815	bacterial-type flagellum-dependent cell motility
CK207_11530	COG0835	chemotaxis
CK207_11530	COG0784	Response regulator, receiver
CK207_11540	COG2747	anti-sigma28 factor FlgM
CK207_11585	COG2217	Heavy metal translocating P-type atpase
CK207_11585	COG2608	mercury ion transmembrane transporter activity
CK207_11610	COG3385	transposase activity
CK207_11615	COG1187	pseudouridine synthase activity
CK207_11620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CK207_11625	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CK207_11630	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CK207_11635	COG0121	glutamine amidotransferase
CK207_11640	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CK207_11655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CK207_11665	COG2226	methyltransferase
CK207_11670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK207_11675	COG0741	lytic transglycosylase activity
CK207_11675	COG1388	LysM domain
CK207_11690	COG0347	Belongs to the P(II) protein family
CK207_11700	COG0037	tRNA processing
CK207_11705	COG0825	malonyl-CoA metabolic process
CK207_11710	COG0587	DNA-directed DNA polymerase activity
CK207_11720	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CK207_11730	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CK207_11735	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CK207_11740	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CK207_11750	COG0750	zinc metalloprotease
CK207_11755	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CK207_11760	COG0575	Belongs to the CDS family
CK207_11765	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CK207_11770	COG0233	cytoplasmic translational termination
CK207_11780	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CK207_11785	COG0052	Belongs to the universal ribosomal protein uS2 family
CK207_11790	COG0024	Methionine aminopeptidase
CK207_11805	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CK207_11810	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CK207_11835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CK207_11835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CK207_11845	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CK207_11870	COG2252	PERMEase
CK207_11875	COG2195	Cleaves the N-terminal amino acid of tripeptides
CK207_11880	COG0189	ligase activity
CK207_11880	COG4067	protein conserved in archaea
CK207_11885	COG0189	ligase activity
CK207_11895	COG0733	neurotransmitter:sodium symporter activity
CK207_11900	COG3706	GGDEF domain
CK207_11900	COG4251	negative regulation of phosphorylation
CK207_11900	COG2203	Gaf domain
CK207_11900	COG5001	Diguanylate cyclase
CK207_11910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CK207_11920	COG1477	protein flavinylation
CK207_11955	COG0271	Belongs to the BolA IbaG family
CK207_11975	COG2211	Major facilitator Superfamily
CK207_11985	COG1595	DNA-templated transcription, initiation
CK207_12000	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CK207_12010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CK207_12015	COG2166	iron-sulfur cluster assembly
CK207_12020	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CK207_12025	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CK207_12035	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CK207_12035	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CK207_12045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CK207_12050	COG1074	ATP-dependent DNA helicase activity
CK207_12055	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CK207_12070	COG3141	response to X-ray
CK207_12075	COG2171	N-acyltransferase activity
CK207_12105	COG1609	Transcriptional regulator
CK207_12115	COG1085	galactose-1-phosphate uridylyltransferase
CK207_12130	COG0784	Response regulator, receiver
CK207_12130	COG3437	response regulator, receiver
CK207_12135	COG1022	Amp-dependent synthetase and ligase
CK207_12140	COG4628	conserved protein (DUF2132)
CK207_12145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CK207_12150	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CK207_12160	COG0560	Phosphoserine phosphatase
CK207_12170	COG0813	purine-nucleoside phosphorylase activity
CK207_12175	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CK207_12185	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CK207_12190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK207_12195	COG0084	hydrolase, TatD family'
CK207_12205	COG1115	amino acid carrier protein
CK207_12220	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CK207_12225	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CK207_12230	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CK207_12235	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CK207_12240	COG0083	homoserine kinase activity
CK207_12255	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CK207_12260	COG3335	DDE superfamily endonuclease
CK207_12265	COG0745	RESPONSE REGULATOR receiver
CK207_12275	COG5002	protein histidine kinase activity
CK207_12275	COG2198	Histidine kinase
CK207_12275	COG0784	Response regulator, receiver
CK207_12280	COG1242	4 iron, 4 sulfur cluster binding
CK207_12285	COG0069	glutamate synthase activity
CK207_12285	COG0067	glutamate synthase
CK207_12285	COG0070	glutamate synthase
CK207_12295	COG0070	glutamate synthase
CK207_12295	COG0067	glutamate synthase
CK207_12295	COG0069	glutamate synthase activity
CK207_12300	COG0493	'glutamate synthase
CK207_12320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CK207_12325	COG2860	membrane
CK207_12330	COG0583	DNA-binding transcription factor activity
CK207_12335	COG0730	response to heat
CK207_12345	COG0505	Belongs to the CarA family
CK207_12355	COG0494	nUDIX hydrolase
CK207_12360	COG0653	protein targeting
CK207_12370	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CK207_12375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CK207_12380	COG0849	cell division
CK207_12385	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CK207_12390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CK207_12395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CK207_12400	COG0772	Belongs to the SEDS family
CK207_12405	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CK207_12410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CK207_12415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CK207_12420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CK207_12425	COG0768	penicillin binding
CK207_12430	COG3116	cell division
CK207_12445	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CK207_12450	COG3107	peptidoglycan biosynthetic process
CK207_12460	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CK207_12470	COG2969	positive regulation of protein catabolic process
CK207_12475	COG0625	glutathione transferase activity
CK207_12480	COG2857	Cytochrome c1
CK207_12485	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CK207_12490	COG0723	plastoquinol--plastocyanin reductase activity
CK207_12510	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CK207_12515	COG3105	Protein conserved in bacteria
CK207_12520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CK207_12525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CK207_12530	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CK207_12535	COG0187	DNA topoisomerase II activity
CK207_12540	COG3150	esterase
CK207_12550	COG3151	Protein conserved in bacteria
CK207_12555	COG0494	nUDIX hydrolase
CK207_12560	COG1538	Outer membrane efflux protein
CK207_12570	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CK207_12585	COG3025	triphosphatase activity
CK207_12590	COG1392	Phosphate transport regulator
CK207_12595	COG0306	phosphate transporter
CK207_12600	COG4991	sh3 domain protein
CK207_12610	COG3267	Type II secretory pathway component ExeA
CK207_12610	COG3409	Peptidoglycan-binding domain 1 protein
CK207_12615	COG0617	tRNA 3'-terminal CCA addition
CK207_12625	COG0504	CTP synthase activity
CK207_12630	COG3956	TIGRFAM MazG family protein
CK207_12635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CK207_12640	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CK207_12645	COG4999	Histidine kinase
CK207_12645	COG3437	response regulator, receiver
CK207_12645	COG2205	protein histidine kinase activity
CK207_12645	COG3850	Histidine kinase
CK207_12650	COG0736	holo-[acyl-carrier-protein] synthase activity
CK207_12675	COG0681	Belongs to the peptidase S26 family
CK207_12680	COG0481	GTPase activity
CK207_12685	COG3086	response to oxidative stress
CK207_12700	COG1595	DNA-templated transcription, initiation
CK207_12705	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CK207_12715	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CK207_12720	COG0354	folic acid binding
CK207_12735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK207_12740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK207_12750	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CK207_12760	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CK207_12770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CK207_12780	COG0028	Belongs to the TPP enzyme family
CK207_12785	COG1022	Amp-dependent synthetase and ligase
CK207_12790	COG0583	DNA-binding transcription factor activity
CK207_12795	COG3335	DDE superfamily endonuclease
CK207_12810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CK207_12815	COG0473	3-isopropylmalate dehydrogenase activity
CK207_12825	COG0066	3-isopropylmalate dehydratase activity
CK207_12875	COG3328	transposase activity
CK207_12895	COG0795	lipopolysaccharide-transporting ATPase activity
CK207_12900	COG0795	lipopolysaccharide-transporting ATPase activity
CK207_12905	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CK207_12910	COG2927	DNA polymerase III (CHI subunit)
CK207_12915	COG0525	valine-tRNA ligase activity
CK207_12920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CK207_12925	COG0564	pseudouridine synthase activity
CK207_12935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CK207_12945	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CK207_12960	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CK207_12965	COG0251	oxidation-reduction process
CK207_12980	COG0204	Acyl-transferase
CK207_12985	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CK207_12990	COG5007	Belongs to the BolA IbaG family
CK207_13000	COG2854	intermembrane phospholipid transfer
CK207_13005	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CK207_13010	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CK207_13015	COG1127	ABC transporter
CK207_13025	COG0517	IMP dehydrogenase activity
CK207_13025	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CK207_13040	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CK207_13045	COG1137	ATPase activity
CK207_13055	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CK207_13060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_13070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_13075	COG2239	Acts as a magnesium transporter
CK207_13080	COG0312	modulator of DNA gyrase
CK207_13085	COG3028	Belongs to the UPF0307 family
CK207_13090	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CK207_13095	COG1178	ABC-type Fe3 transport system permease component
CK207_13100	COG4143	(ABC) transporter
CK207_13105	COG0163	prenyltransferase activity
CK207_13110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CK207_13115	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CK207_13120	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CK207_13130	COG2105	PFAM AIG2 family protein
CK207_13135	COG2911	Protein conserved in bacteria
CK207_13140	COG0729	surface antigen
CK207_13145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CK207_13150	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CK207_13185	COG0529	Catalyzes the synthesis of activated sulfate
CK207_13190	COG2895	sulfate adenylyltransferase (ATP) activity
CK207_13195	COG0175	sulfate reduction
CK207_13200	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CK207_13200	COG1648	precorrin-2 dehydrogenase activity
CK207_13230	COG3335	DDE superfamily endonuclease
CK207_13255	COG0513	Belongs to the DEAD box helicase family
CK207_13260	COG2153	protein acetylation
CK207_13265	COG3266	domain, Protein
CK207_13265	COG3061	Opacity-associated protein A
CK207_13270	COG0545	Peptidyl-prolyl cis-trans isomerase
CK207_13275	COG0203	ribosomal protein L17
CK207_13285	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CK207_13290	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CK207_13295	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CK207_13305	COG0201	protein transport
CK207_13330	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CK207_13335	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CK207_13355	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CK207_13360	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CK207_13385	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CK207_13410	COG0051	transcription antitermination factor activity, RNA binding
CK207_13415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CK207_13420	COG0557	exoribonuclease II activity
CK207_13425	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CK207_13435	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CK207_13445	COG1047	Peptidyl-prolyl cis-trans
CK207_13450	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CK207_13460	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK207_13465	COG0488	(ABC) transporter
CK207_13475	COG0429	hydrolase of the alpha beta-hydrolase fold
CK207_13485	COG3954	Phosphoribulokinase
CK207_13490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CK207_13510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CK207_13525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK207_13535	COG0583	DNA-binding transcription factor activity
CK207_13550	COG0180	Tryptophanyl-tRNA synthetase
CK207_13555	COG0546	phosphoglycolate phosphatase activity
CK207_13560	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CK207_13565	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CK207_13580	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CK207_13610	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CK207_13620	COG0678	peroxiredoxin activity
CK207_13620	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CK207_13625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK207_13635	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CK207_13635	COG0165	Argininosuccinate lyase
CK207_13645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CK207_13650	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CK207_13670	COG1045	serine acetyltransferase
CK207_13675	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CK207_13685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CK207_13690	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CK207_13695	COG1053	succinate dehydrogenase
CK207_13700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CK207_13705	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CK207_13715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CK207_13720	COG1509	lysine 2,3-aminomutase activity
CK207_13745	COG0459	protein refolding
CK207_13775	COG0149	triose-phosphate isomerase activity
CK207_13780	COG0534	Mate efflux family protein
CK207_13855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CK207_13860	COG1575	Belongs to the MenA family. Type 1 subfamily
CK207_13880	COG1609	Transcriptional regulator
CK207_13885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CK207_13895	COG0281	malic enzyme
CK207_13905	COG0626	cystathionine gamma-synthase activity
CK207_13910	COG0527	aspartate kinase activity
CK207_13910	COG0460	homoserine dehydrogenase
CK207_13915	COG3385	transposase activity
CK207_13920	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CK207_13930	COG1494	fructose-1,6-bisphosphatase
CK207_13935	COG0205	6-phosphofructokinase activity
CK207_13940	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CK207_13950	COG0745	RESPONSE REGULATOR receiver
CK207_13955	COG2205	protein histidine kinase activity
CK207_13960	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CK207_13965	COG1278	Cold shock
CK207_13970	COG3030	protein affecting phage T7 exclusion by the F plasmid
CK207_13975	COG1027	Aspartate ammonia-lyase
CK207_13980	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CK207_13985	COG1288	antiporter activity
CK207_13995	COG0549	Belongs to the carbamate kinase family
CK207_14000	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CK207_14010	COG0540	Belongs to the ATCase OTCase family
CK207_14015	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CK207_14020	COG1438	arginine binding
CK207_14025	COG4232	protein-disulfide reductase activity
CK207_14035	COG3263	regulation of cellular component size
CK207_14045	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CK207_14050	COG2205	protein histidine kinase activity
CK207_14050	COG0784	Response regulator, receiver
CK207_14050	COG2198	Histidine kinase
CK207_14055	COG2814	Major facilitator Superfamily
CK207_14070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CK207_14075	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CK207_14080	COG0511	ligase activity, forming carbon-carbon bonds
CK207_14085	COG0439	Biotin carboxylase
CK207_14090	COG2264	protein methyltransferase activity
CK207_14095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CK207_14100	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CK207_14105	COG0840	transmembrane signaling receptor activity
CK207_14110	COG0789	Transcriptional regulator
CK207_14120	COG0151	Belongs to the GarS family
CK207_14130	COG0776	regulation of translation
CK207_14135	COG1253	flavin adenine dinucleotide binding
CK207_14180	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CK207_14190	COG3068	Protein conserved in bacteria
CK207_14195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CK207_14200	COG0668	transmembrane transport
CK207_14215	COG4372	Transposase
CK207_14240	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CK207_14250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CK207_14315	COG3335	DDE superfamily endonuclease
CK207_14335	COG0367	asparagine synthase
CK207_14360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CK207_14370	COG5433	transposase activity
CK207_14395	COG3307	-O-antigen
CK207_14405	COG0859	PFAM glycosyl transferase family 9
CK207_14420	COG1519	Transferase
CK207_14450	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CK207_14450	COG2755	lipolytic protein G-D-S-L family
CK207_14455	COG3642	lipopolysaccharide core region biosynthetic process
CK207_14460	COG0859	PFAM glycosyl transferase family 9
CK207_14465	COG0463	Glycosyl transferase, family 2
CK207_14470	COG0859	PFAM glycosyl transferase family 9
CK207_14475	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CK207_14480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CK207_14490	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CK207_14505	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CK207_14510	COG1309	transcriptional regulator
CK207_14515	COG1560	Kdo2-lipid A biosynthetic process
CK207_14520	COG1560	Kdo2-lipid A biosynthetic process
CK207_14530	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CK207_14535	COG1561	YicC-like family, N-terminal region
CK207_14550	COG3385	transposase activity
CK207_14555	COG0612	Peptidase, M16
CK207_14575	COG1120	ATPase activity
CK207_14580	COG4774	siderophore transport
CK207_14585	COG1132	(ABC) transporter
CK207_14590	COG1263	PTS System
CK207_14590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK207_14595	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CK207_14615	COG0514	ATP-dependent DNA helicase (RecQ)
CK207_14620	COG2962	Rard protein
CK207_14630	COG1280	lysine exporter protein (LysE YggA)
CK207_14635	COG0210	DNA helicase
CK207_14640	COG0339	signal peptide processing
CK207_14645	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CK207_14650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK207_14685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK207_14740	COG1309	transcriptional regulator
CK207_14745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK207_14750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK207_14755	COG2960	long-chain fatty acid transporting porin activity
CK207_14765	COG0583	DNA-binding transcription factor activity
CK207_14770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CK207_14795	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CK207_14800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CK207_14800	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CK207_14810	COG0084	hydrolase, TatD family'
CK207_14825	COG0805	protein transport
CK207_14830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CK207_14840	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CK207_14855	COG1322	Protein conserved in bacteria
CK207_14860	COG0697	spore germination
CK207_14925	COG2433	Pfam Transposase IS66
CK207_14955	COG2433	Pfam Transposase IS66
CK207_14960	COG3335	DDE superfamily endonuclease
CK207_14980	COG2433	Pfam Transposase IS66
CK207_15010	COG0606	chelatase, subunit chli
CK207_15020	COG3978	acetolactate synthase activity
CK207_15025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CK207_15030	COG0129	dihydroxy-acid dehydratase activity
CK207_15040	COG0604	alcohol dehydrogenase
CK207_15065	COG2119	membrane
CK207_15070	COG0752	glycyl-tRNA synthetase alpha subunit
CK207_15080	COG3977	Valine--pyruvate aminotransferase
CK207_15085	COG0071	Belongs to the small heat shock protein (HSP20) family
CK207_15105	COG0187	DNA topoisomerase II activity
CK207_15110	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CK207_15115	COG0592	DNA-directed DNA polymerase activity
CK207_15135	COG1126	abc transporter atp-binding protein
CK207_15150	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CK207_15155	COG0706	membrane insertase activity
CK207_15165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CK207_15195	COG2084	Dehydrogenase
CK207_15200	COG0814	amino acid
CK207_15230	COG0583	DNA-binding transcription factor activity
CK207_15235	COG2910	NAD(P)H-binding
CK207_15245	COG3304	Inner membrane component domain
CK207_15265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CK207_15270	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CK207_15290	COG0363	glucosamine-6-phosphate deaminase activity
CK207_15300	COG0739	heme binding
CK207_15305	COG2213	PTS system mannitol-specific
CK207_15305	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_15310	COG0246	Mannitol dehydrogenase
CK207_15315	COG3722	fumarate hydratase activity
CK207_15325	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CK207_15330	COG1301	dicarboxylic acid transport
CK207_15335	COG2259	Doxx family
CK207_15355	COG1566	PFAM secretion protein HlyD family protein
CK207_15360	COG1846	Transcriptional regulator
CK207_15370	COG3046	protein related to deoxyribodipyrimidine photolyase
CK207_15375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CK207_15385	COG3335	DDE superfamily endonuclease
CK207_15395	COG1131	(ABC) transporter
CK207_15410	COG3842	ATPase activity
CK207_15420	COG1176	ABC-type spermidine putrescine transport system, permease component I
CK207_15440	COG0513	Belongs to the DEAD box helicase family
CK207_15445	COG0251	oxidation-reduction process
CK207_15450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CK207_15460	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CK207_15465	COG1328	CTP reductase activity
CK207_15475	COG2130	NADP-dependent
CK207_15480	COG1309	transcriptional regulator
CK207_15495	COG0745	RESPONSE REGULATOR receiver
CK207_15505	COG0564	pseudouridine synthase activity
CK207_15510	COG3335	DDE superfamily endonuclease
CK207_15520	COG3335	DDE superfamily endonuclease
CK207_15560	COG3335	DDE superfamily endonuclease
CK207_15610	COG3501	Rhs element vgr protein
CK207_15655	COG2433	Pfam Transposase IS66
CK207_15680	COG0471	metal ion transport
CK207_15685	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CK207_15690	COG3335	DDE superfamily endonuclease
CK207_15700	COG2188	Transcriptional regulator
CK207_15705	COG1131	(ABC) transporter
CK207_15735	COG0671	phosphoesterase, PA-phosphatase related
CK207_15740	COG4399	Belongs to the UPF0754 family
CK207_15745	COG1132	(ABC) transporter
CK207_15765	COG3623	hexulose-6-phosphate isomerase
CK207_15770	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CK207_15775	COG0561	phosphatase activity
CK207_15825	COG3335	DDE superfamily endonuclease
CK207_15840	COG0366	Alpha amylase catalytic
CK207_15850	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CK207_15860	COG1999	signal sequence binding
CK207_15875	COG0786	glutamate:sodium symporter activity
CK207_15905	COG1566	PFAM secretion protein HlyD family protein
CK207_15915	COG3706	GGDEF domain
CK207_15930	COG0813	purine-nucleoside phosphorylase activity
CK207_15935	COG3272	Protein of unknown function (DUF1722)
CK207_15940	COG0789	Transcriptional regulator
CK207_15945	COG0415	Belongs to the DNA photolyase family
CK207_15950	COG1388	LysM domain
CK207_15950	COG1376	ErfK ybiS ycfS ynhG family protein
CK207_15960	COG0513	Belongs to the DEAD box helicase family
CK207_15990	COG2267	carboxylic ester hydrolase activity
CK207_16000	COG0366	Alpha amylase catalytic
CK207_16005	COG4989	oxidoreductase activity
CK207_16015	COG1136	(ABC) transporter
CK207_16015	COG0577	efflux transmembrane transporter activity
CK207_16020	COG1136	(ABC) transporter
CK207_16020	COG0577	efflux transmembrane transporter activity
CK207_16035	COG2972	Histidine kinase
CK207_16035	COG0745	RESPONSE REGULATOR receiver
CK207_16040	COG3279	Response regulator of the LytR AlgR family
CK207_16045	COG2203	Gaf domain
CK207_16045	COG3706	GGDEF domain
CK207_16045	COG4251	negative regulation of phosphorylation
CK207_16045	COG5001	Diguanylate cyclase
CK207_16055	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CK207_16065	COG3437	response regulator, receiver
CK207_16070	COG4999	Histidine kinase
CK207_16070	COG2205	protein histidine kinase activity
CK207_16070	COG3437	response regulator, receiver
CK207_16070	COG3850	Histidine kinase
CK207_16080	COG0531	amino acid
CK207_16125	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK207_16145	COG2433	Pfam Transposase IS66
CK207_16155	COG1609	Transcriptional regulator
CK207_16160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_16180	COG0673	inositol 2-dehydrogenase activity
CK207_16185	COG1765	OsmC-like protein
CK207_16190	COG0110	maltose O-acetyltransferase activity
CK207_16205	COG0583	DNA-binding transcription factor activity
CK207_16215	COG0583	DNA-binding transcription factor activity
CK207_16220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CK207_16225	COG3186	Phenylalanine-4-hydroxylase
CK207_16235	COG0840	transmembrane signaling receptor activity
CK207_16240	COG0534	Mate efflux family protein
CK207_16245	COG2207	Transcriptional regulator
CK207_16250	COG0784	Response regulator, receiver
CK207_16250	COG3437	response regulator, receiver
CK207_16260	COG4191	Histidine kinase
CK207_16260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK207_16305	COG3240	lipase activity
CK207_16315	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CK207_16320	COG5380	lipid catabolic process
CK207_16325	COG4412	M6 family metalloprotease domain protein
CK207_16325	COG3291	Pkd domain containing protein
CK207_16350	COG4607	ABC-type enterochelin transport system periplasmic component
CK207_16355	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK207_16360	COG4605	iron ion homeostasis
CK207_16365	COG4604	ABC transporter, ATP-binding protein
CK207_16380	COG3344	reverse transcriptase
CK207_16390	COG2814	Major facilitator Superfamily
CK207_16415	COG0861	Integral membrane protein TerC family
CK207_16430	COG0697	spore germination
CK207_16460	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CK207_16485	COG0612	Peptidase, M16
CK207_16500	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CK207_16500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK207_16500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK207_16505	COG1105	Belongs to the carbohydrate kinase PfkB family
CK207_16510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_16510	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_16515	COG1609	Transcriptional regulator
CK207_16520	COG0420	3'-5' exonuclease activity
CK207_16525	COG0419	ATPase involved in DNA repair
CK207_16530	COG2205	protein histidine kinase activity
CK207_16530	COG0784	Response regulator, receiver
CK207_16535	COG0156	8-amino-7-oxononanoate synthase activity
CK207_16545	COG0038	chloride channel
CK207_16550	COG0523	cobalamin synthesis protein
CK207_16555	COG1136	(ABC) transporter
CK207_16565	COG1136	(ABC) transporter
CK207_16565	COG0577	efflux transmembrane transporter activity
CK207_16580	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CK207_16600	COG3335	DDE superfamily endonuclease
CK207_16640	COG3730	PTS system glucitol sorbitol-specific
CK207_16655	COG1028	Short-chain dehydrogenase reductase Sdr
CK207_16660	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_16665	COG1349	DNA-binding transcription factor activity
CK207_16670	COG3730	PTS system glucitol sorbitol-specific
CK207_16700	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK207_16705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK207_16715	COG3005	denitrification pathway
CK207_16725	COG0243	molybdopterin cofactor binding
CK207_16735	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CK207_16740	COG3850	Histidine kinase
CK207_16745	COG2197	response regulator
CK207_16750	COG3069	C4-dicarboxylate transmembrane transporter activity
CK207_16775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CK207_16785	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CK207_16790	COG0513	Belongs to the DEAD box helicase family
CK207_16840	COG2801	Transposase and inactivated derivatives
CK207_16875	COG4682	membrane
CK207_16885	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CK207_16920	COG2433	Pfam Transposase IS66
CK207_17060	COG2433	Pfam Transposase IS66
CK207_17100	COG0242	peptide deformylase activity
CK207_17180	COG2433	Pfam Transposase IS66
CK207_17230	COG2433	Pfam Transposase IS66
CK207_17310	COG3549	Plasmid maintenance system killer
CK207_17315	COG3093	addiction module antidote protein HigA
CK207_17325	COG0346	lactoylglutathione lyase activity
CK207_17350	COG2433	Pfam Transposase IS66
CK207_17370	COG2433	Pfam Transposase IS66
CK207_17375	COG2161	toxin-antitoxin pair type II binding
CK207_17380	COG4115	mRNA cleavage
CK207_17440	COG2433	Pfam Transposase IS66
CK207_17455	COG2433	Pfam Transposase IS66
CK207_17485	COG0602	queuosine metabolic process
CK207_17490	COG1328	CTP reductase activity
CK207_17495	COG1328	CTP reductase activity
CK207_17515	COG2433	Pfam Transposase IS66
CK207_17535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK207_17645	COG3335	DDE superfamily endonuclease
CK207_17710	COG2433	Pfam Transposase IS66
CK207_17765	COG3040	lipid binding
CK207_17805	COG4067	protein conserved in archaea
CK207_17805	COG0189	ligase activity
CK207_17820	COG4166	transmembrane transport
CK207_17825	COG4174	ABC transporter (Permease)
CK207_17830	COG4239	(ABC) transporter, permease
CK207_17850	COG3038	cytochrome b561
CK207_17855	COG2353	YceI-like domain
CK207_17860	COG0840	transmembrane signaling receptor activity
CK207_17865	COG3335	DDE superfamily endonuclease
CK207_17870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CK207_17875	COG0545	Peptidyl-prolyl cis-trans isomerase
CK207_17890	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CK207_17910	COG2897	thiosulfate sulfurtransferase activity
CK207_17915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CK207_17920	COG0303	'Molybdopterin
CK207_17925	COG0302	gtp cyclohydrolase
CK207_17930	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CK207_17930	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CK207_17935	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CK207_17940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CK207_17945	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CK207_17955	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CK207_17960	COG1011	Hydrolase
CK207_17965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CK207_17970	COG2188	Transcriptional regulator
CK207_17990	COG2116	formate transmembrane transporter activity
CK207_17995	COG0583	DNA-binding transcription factor activity
CK207_18005	COG3593	DNA synthesis involved in DNA repair
CK207_18010	COG0737	Belongs to the 5'-nucleotidase family
CK207_18015	COG0861	Integral membrane protein TerC family
CK207_18030	COG2824	Alkylphosphonate utilization operon protein PhnA
CK207_18040	COG2050	protein possibly involved in aromatic compounds catabolism
CK207_18055	COG0488	(ABC) transporter
CK207_18075	COG0625	glutathione transferase activity
CK207_18080	COG2501	S4 domain
CK207_18095	COG0840	transmembrane signaling receptor activity
CK207_18105	COG1278	Cold shock
CK207_18115	COG3335	DDE superfamily endonuclease
CK207_18135	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CK207_18140	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CK207_18150	COG0745	RESPONSE REGULATOR receiver
CK207_18165	COG3140	Belongs to the UPF0181 family
CK207_18170	COG2433	Pfam Transposase IS66
CK207_18205	COG2433	Pfam Transposase IS66
CK207_18235	COG2433	Pfam Transposase IS66
CK207_18270	COG0583	DNA-binding transcription factor activity
CK207_18275	COG0045	succinate-CoA ligase (ADP-forming) activity
CK207_18275	COG1042	CoA-binding domain protein
CK207_18275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK207_18285	COG1181	Belongs to the D-alanine--D-alanine ligase family
CK207_18300	COG0023	Translation Initiation Factor
CK207_18390	COG3335	DDE superfamily endonuclease
CK207_18420	COG2433	Pfam Transposase IS66
CK207_18465	COG0724	RNA recognition motif
CK207_18480	COG3041	Addiction module toxin RelE StbE family
CK207_18500	COG2433	Pfam Transposase IS66
CK207_18515	COG5001	Diguanylate cyclase
CK207_18515	COG3300	MHYT domain
CK207_18525	COG5002	protein histidine kinase activity
CK207_18535	COG0745	RESPONSE REGULATOR receiver
CK207_18550	COG2203	Gaf domain
CK207_18550	COG3706	GGDEF domain
CK207_18550	COG4251	negative regulation of phosphorylation
CK207_18550	COG5001	Diguanylate cyclase
CK207_18560	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CK207_18565	COG4149	molybdate abc transporter
CK207_18570	COG0725	ABC transporter, periplasmic molybdate-binding protein
CK207_18575	COG1492	cobalamin metabolic process
CK207_18580	COG3111	PFAM Bacterial OB fold (BOF) protein
CK207_18590	COG5001	Diguanylate cyclase
CK207_18590	COG3447	MASE1 domain protein
CK207_18590	COG5002	protein histidine kinase activity
CK207_18595	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CK207_18605	COG2207	Transcriptional regulator
CK207_18610	COG1979	alcohol dehydrogenase
CK207_18625	COG1840	ABC-type Fe3 transport system, periplasmic component
CK207_18635	COG2271	Major facilitator Superfamily
CK207_18640	COG0469	pyruvate kinase activity
CK207_18645	COG2205	protein histidine kinase activity
CK207_18645	COG0784	Response regulator, receiver
CK207_18645	COG2198	Histidine kinase
CK207_18650	COG1879	ABC-type sugar transport system periplasmic component
CK207_18655	COG1803	Methylglyoxal synthase
CK207_18660	COG0210	DNA helicase
CK207_18665	COG1289	transmembrane transporter activity
CK207_18695	COG5002	protein histidine kinase activity
CK207_18695	COG0784	Response regulator, receiver
CK207_18710	COG2827	Endonuclease containing a URI domain
CK207_18735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CK207_18740	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CK207_18745	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CK207_18750	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CK207_18755	COG0247	lactate metabolic process
CK207_18760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CK207_18765	COG3118	belongs to the thioredoxin family
CK207_18785	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CK207_18800	COG2146	nitrite reductase [NAD(P)H] activity
CK207_18805	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK207_18810	COG3328	transposase activity
CK207_18840	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CK207_18855	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CK207_18865	COG0513	Belongs to the DEAD box helicase family
CK207_18875	COG0814	amino acid
CK207_18885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CK207_18890	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CK207_18900	COG1984	allophanate hydrolase subunit 2
CK207_18910	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CK207_18915	COG4181	ATPase activity
CK207_18925	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CK207_18930	COG1716	ATPase activity
CK207_18930	COG5001	Diguanylate cyclase
CK207_18940	COG0484	heat shock protein binding
CK207_18975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK207_18980	COG3300	MHYT domain
CK207_18980	COG5001	Diguanylate cyclase
CK207_19000	COG0010	Belongs to the arginase family
CK207_19005	COG1166	arginine decarboxylase activity
CK207_19020	COG4176	ABC-type proline glycine betaine transport system permease component
CK207_19025	COG3344	reverse transcriptase
CK207_19030	COG2113	Glycine betaine
CK207_19050	COG0527	aspartate kinase activity
CK207_19055	COG0662	Cupin 2, conserved barrel domain protein
CK207_19060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CK207_19065	COG0456	acetyltransferase
CK207_19075	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CK207_19110	COG3335	DDE superfamily endonuclease
CK207_19120	COG0366	Alpha amylase catalytic
CK207_19140	COG0714	Associated with various cellular activities
CK207_19160	COG2304	oxidoreductase activity
CK207_19175	COG3706	GGDEF domain
CK207_19185	COG1403	HNH endonuclease
CK207_19190	COG3530	Putative quorum-sensing-regulated virulence factor
CK207_19195	COG1368	sulfuric ester hydrolase activity
CK207_19205	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CK207_19245	COG1063	alcohol dehydrogenase
CK207_19250	COG0156	8-amino-7-oxononanoate synthase activity
CK207_19260	COG0346	lactoylglutathione lyase activity
CK207_19275	COG2197	response regulator
CK207_19280	COG3851	Histidine kinase
CK207_19285	COG2271	Major facilitator Superfamily
CK207_19320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CK207_19325	COG0640	Transcriptional regulator
CK207_19330	COG0798	PFAM Bile acid sodium symporter
CK207_19335	COG0640	Transcriptional regulator
CK207_19340	COG0659	secondary active sulfate transmembrane transporter activity
CK207_19345	COG0589	response to stress
CK207_19370	COG1917	Cupin 2, conserved barrel domain protein
CK207_19370	COG4977	sequence-specific DNA binding
CK207_19375	COG4771	TonB-dependent receptor
CK207_19380	COG2814	Major facilitator Superfamily
CK207_19385	COG3433	isochorismatase activity
CK207_19385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK207_19385	COG2226	methyltransferase
CK207_19410	COG1021	2,3-dihydroxybenzoate-AMP ligase
CK207_19415	COG1132	(ABC) transporter
CK207_19420	COG1132	(ABC) transporter
CK207_19455	COG0714	Associated with various cellular activities
CK207_19490	COG2433	Pfam Transposase IS66
CK207_19515	COG3335	DDE superfamily endonuclease
CK207_19520	COG1196	nuclear chromosome segregation
CK207_19525	COG0732	type I restriction modification DNA specificity domain
CK207_19530	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CK207_19540	COG2204	response regulator
CK207_19595	COG3501	Rhs element vgr protein
CK207_19645	COG0516	GMP reductase activity
CK207_19650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CK207_19675	COG1278	Cold shock
CK207_19680	COG4681	YaeQ
CK207_19685	COG1017	nitric oxide dioxygenase activity
CK207_19685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CK207_19690	COG3604	Transcriptional regulator
CK207_19710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK207_19715	COG0633	Ferredoxin
CK207_19715	COG3217	Mosc domain protein beta barrel domain protein
CK207_19725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CK207_19730	COG2354	Protein conserved in bacteria
CK207_19750	COG3706	GGDEF domain
CK207_19755	COG1349	DNA-binding transcription factor activity
CK207_19785	COG1175	transmembrane transport
CK207_19800	COG3842	ATPase activity
CK207_19810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CK207_19815	COG0835	chemotaxis
CK207_19815	COG0784	Response regulator, receiver
CK207_19820	COG2315	Protein conserved in bacteria
CK207_19825	COG3335	DDE superfamily endonuclease
CK207_19830	COG3706	GGDEF domain
CK207_19865	COG5001	Diguanylate cyclase
CK207_19875	COG1741	Belongs to the pirin family
CK207_19895	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CK207_19905	COG0765	amino acid transport
CK207_19910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK207_19915	COG0765	amino acid transport
CK207_19920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CK207_19940	COG0179	Fumarylacetoacetate (FAA) hydrolase
CK207_19950	COG0697	spore germination
CK207_19970	COG2814	Major facilitator Superfamily
CK207_19975	COG0583	DNA-binding transcription factor activity
CK207_19980	COG5001	Diguanylate cyclase
CK207_19985	COG0739	heme binding
CK207_19995	COG0659	secondary active sulfate transmembrane transporter activity
CK207_20020	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CK207_20025	COG0581	inorganic phosphate transmembrane transporter activity
CK207_20030	COG0573	inorganic phosphate transmembrane transporter activity
CK207_20035	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CK207_20045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK207_20050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK207_20090	COG2271	Major facilitator Superfamily
CK207_20095	COG0584	glycerophosphoryl diester phosphodiesterase
CK207_20105	COG3527	Alpha-acetolactate decarboxylase
CK207_20130	COG0583	DNA-binding transcription factor activity
CK207_20135	COG1620	l-lactate permease
CK207_20140	COG1304	FMN binding
CK207_20155	COG1881	PFAM PEBP family protein
CK207_20170	COG1230	cation diffusion facilitator family transporter
CK207_20175	COG3122	Protein conserved in bacteria
CK207_20185	COG3568	Endonuclease Exonuclease Phosphatase
CK207_20200	COG3335	DDE superfamily endonuclease
CK207_20210	COG0840	transmembrane signaling receptor activity
CK207_20220	COG1472	Belongs to the glycosyl hydrolase 3 family
CK207_20225	COG3842	ATPase activity
CK207_20245	COG2211	Major facilitator Superfamily
CK207_20255	COG1067	ATP-dependent peptidase activity
CK207_20265	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CK207_20270	COG0363	glucosamine-6-phosphate deaminase activity
CK207_20280	COG0583	DNA-binding transcription factor activity
CK207_20295	COG1609	Transcriptional regulator
CK207_20300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK207_20305	COG1879	ABC-type sugar transport system periplasmic component
CK207_20310	COG1172	Belongs to the binding-protein-dependent transport system permease family
CK207_20315	COG1129	ABC transporter
CK207_20320	COG1869	D-ribose catabolic process
CK207_20335	COG2433	Pfam Transposase IS66
CK207_20375	COG3501	Rhs element vgr protein
CK207_20385	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CK207_20390	COG1640	4-alpha-glucanotransferase
CK207_20395	COG0058	SHG alpha-glucan phosphorylase activity
CK207_20400	COG2909	trisaccharide binding
CK207_20420	COG0840	transmembrane signaling receptor activity
CK207_20425	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CK207_20450	COG3335	DDE superfamily endonuclease
CK207_20490	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CK207_20500	COG0259	pyridoxamine-phosphate oxidase activity
CK207_20530	COG3706	GGDEF domain
CK207_20530	COG0745	RESPONSE REGULATOR receiver
CK207_20550	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CK207_20555	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CK207_20560	COG0840	transmembrane signaling receptor activity
CK207_20570	COG0835	chemotaxis
CK207_20580	COG0745	RESPONSE REGULATOR receiver
CK207_20590	COG1444	tRNA N-acetyltransferase activity
CK207_20595	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CK207_20675	COG1715	Restriction endonuclease