locus-tag	class	description
VEA_000001	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VEA_000001	COG2146	nitrite reductase [NAD(P)H] activity
VEA_000011	COG2815	serine threonine protein kinase
VEA_000011	COG0515	serine threonine protein kinase
VEA_000018	COG0631	protein serine/threonine phosphatase activity
VEA_000029	COG3501	Rhs element vgr protein
VEA_000032	COG0420	3'-5' exonuclease activity
VEA_000033	COG0419	ATPase involved in DNA repair
VEA_000036	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VEA_000040	COG0251	oxidation-reduction process
VEA_000042	COG3040	lipid binding
VEA_000044	COG1288	antiporter activity
VEA_000046	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VEA_000049	COG2425	protein containing a von Willebrand factor type A (vWA) domain
VEA_000050	COG0583	DNA-binding transcription factor activity
VEA_000051	COG0277	FAD linked oxidase domain protein
VEA_000054	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VEA_000065	COG5001	Diguanylate cyclase
VEA_000067	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VEA_000068	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VEA_000069	COG2146	nitrite reductase [NAD(P)H] activity
VEA_000071	COG2116	formate transmembrane transporter activity
VEA_000075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VEA_000082	COG2814	Major facilitator Superfamily
VEA_000083	COG3118	belongs to the thioredoxin family
VEA_000084	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VEA_000089	COG2271	Major facilitator Superfamily
VEA_000090	COG3851	Histidine kinase
VEA_000091	COG2197	response regulator
VEA_000093	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VEA_000094	COG0583	DNA-binding transcription factor activity
VEA_000095	COG0243	molybdopterin cofactor binding
VEA_000097	COG0384	phenazine biosynthesis protein PhzF
VEA_000098	COG1794	racemase activity, acting on amino acids and derivatives
VEA_000104	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VEA_000107	COG1328	CTP reductase activity
VEA_000108	COG0602	queuosine metabolic process
VEA_000109	COG0534	Mate efflux family protein
VEA_000110	COG2207	Transcriptional regulator
VEA_000112	COG0189	ligase activity
VEA_000112	COG4067	protein conserved in archaea
VEA_000115	COG3111	PFAM Bacterial OB fold (BOF) protein
VEA_000117	COG0725	ABC transporter, periplasmic molybdate-binding protein
VEA_000118	COG4149	molybdate abc transporter
VEA_000119	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
VEA_000121	COG2203	Gaf domain
VEA_000121	COG5001	Diguanylate cyclase
VEA_000121	COG3706	GGDEF domain
VEA_000121	COG4251	negative regulation of phosphorylation
VEA_000123	COG0745	RESPONSE REGULATOR receiver
VEA_000123	COG3706	GGDEF domain
VEA_000126	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VEA_000127	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VEA_000132	COG3140	Belongs to the UPF0181 family
VEA_000133	COG0589	response to stress
VEA_000135	COG0583	DNA-binding transcription factor activity
VEA_000152	COG0023	Translation Initiation Factor
VEA_000154	COG1181	Belongs to the D-alanine--D-alanine ligase family
VEA_000156	COG0045	succinate-CoA ligase (ADP-forming) activity
VEA_000156	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VEA_000156	COG1042	CoA-binding domain protein
VEA_000157	COG0583	DNA-binding transcription factor activity
VEA_000158	COG4771	TonB-dependent receptor
VEA_000158	COG1629	transport
VEA_000160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VEA_000161	COG5001	Diguanylate cyclase
VEA_000161	COG5002	protein histidine kinase activity
VEA_000161	COG3447	MASE1 domain protein
VEA_000162	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
VEA_000163	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
VEA_000164	COG1984	allophanate hydrolase subunit 2
VEA_000166	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VEA_000167	COG4181	ATPase activity
VEA_000169	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VEA_000170	COG1716	ATPase activity
VEA_000170	COG5001	Diguanylate cyclase
VEA_000178	COG4533	DNA binding
VEA_000180	COG2050	protein possibly involved in aromatic compounds catabolism
VEA_000183	COG2067	long-chain fatty acid transport protein
VEA_000184	COG2267	carboxylic ester hydrolase activity
VEA_000189	COG0737	Belongs to the 5'-nucleotidase family
VEA_000190	COG3593	DNA synthesis involved in DNA repair
VEA_000192	COG0583	DNA-binding transcription factor activity
VEA_000193	COG2116	formate transmembrane transporter activity
VEA_000194	COG2353	YceI-like domain
VEA_000195	COG3038	cytochrome b561
VEA_000198	COG4943	cyclic-guanylate-specific phosphodiesterase activity
VEA_000199	COG0513	Belongs to the DEAD box helicase family
VEA_000200	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
VEA_000202	COG0840	transmembrane signaling receptor activity
VEA_000204	COG0546	phosphoglycolate phosphatase activity
VEA_000207	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VEA_000208	COG2759	Belongs to the formate--tetrahydrofolate ligase family
VEA_000209	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VEA_000211	COG2207	Transcriptional regulator
VEA_000212	COG1979	alcohol dehydrogenase
VEA_000214	COG1126	abc transporter atp-binding protein
VEA_000215	COG0765	amino acid transport
VEA_000216	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VEA_000217	COG0765	amino acid transport
VEA_000218	COG2203	Gaf domain
VEA_000218	COG2200	EAL domain
VEA_000218	COG2199	diguanylate cyclase activity
VEA_000221	COG1609	Transcriptional regulator
VEA_000222	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VEA_000222	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VEA_000223	COG1105	Belongs to the carbohydrate kinase PfkB family
VEA_000224	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VEA_000224	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VEA_000224	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VEA_000228	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VEA_000230	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VEA_000232	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VEA_000233	COG0509	glycine decarboxylation via glycine cleavage system
VEA_000234	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VEA_000234	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VEA_000235	COG0346	lactoylglutathione lyase activity
VEA_000236	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
VEA_000241	COG2176	DNA-directed DNA polymerase activity
VEA_000249	COG0242	peptide deformylase activity
VEA_000256	COG2239	Acts as a magnesium transporter
VEA_000260	COG0346	lactoylglutathione lyase activity
VEA_000261	COG1902	pentaerythritol trinitrate reductase activity
VEA_000266	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
VEA_000267	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VEA_000267	COG0069	glutamate synthase activity
VEA_000273	COG2076	Multidrug Resistance protein
VEA_000278	COG2962	Rard protein
VEA_000281	COG0835	chemotaxis
VEA_000281	COG0784	Response regulator, receiver
VEA_000282	COG2197	response regulator
VEA_000284	COG3706	GGDEF domain
VEA_000286	COG5001	Diguanylate cyclase
VEA_000286	COG3300	MHYT domain
VEA_000287	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
VEA_000291	COG1214	PFAM Peptidase M22, glycoprotease
VEA_000291	COG0456	acetyltransferase
VEA_000293	COG3069	C4-dicarboxylate transmembrane transporter activity
VEA_000294	COG1704	LemA family
VEA_000295	COG0501	Belongs to the peptidase M48B family
VEA_000300	COG3111	PFAM Bacterial OB fold (BOF) protein
VEA_000301	COG1597	lipid kinase activity
VEA_000302	COG0583	DNA-binding transcription factor activity
VEA_000303	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VEA_000303	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VEA_000309	COG0714	Associated with various cellular activities
VEA_000310	COG0641	radical SAM
VEA_000311	COG3119	arylsulfatase activity
VEA_000313	COG3119	arylsulfatase activity
VEA_000317	COG0784	Response regulator, receiver
VEA_000317	COG2198	Histidine kinase
VEA_000317	COG2205	protein histidine kinase activity
VEA_000318	COG1879	ABC-type sugar transport system periplasmic component
VEA_000319	COG1803	Methylglyoxal synthase
VEA_000320	COG0210	DNA helicase
VEA_000321	COG1289	transmembrane transporter activity
VEA_000326	COG4771	TonB-dependent receptor
VEA_000326	COG1629	transport
VEA_000327	COG2207	Transcriptional regulator
VEA_000328	COG0789	Transcriptional regulator
VEA_000329	COG4604	ABC transporter, ATP-binding protein
VEA_000330	COG4605	iron ion homeostasis
VEA_000331	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VEA_000332	COG4607	ABC-type enterochelin transport system periplasmic component
VEA_000334	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VEA_000337	COG1609	Transcriptional regulator
VEA_000338	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VEA_000339	COG1879	ABC-type sugar transport system periplasmic component
VEA_000340	COG1172	Belongs to the binding-protein-dependent transport system permease family
VEA_000341	COG1129	ABC transporter
VEA_000342	COG1869	D-ribose catabolic process
VEA_000343	COG5001	Diguanylate cyclase
VEA_000352	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
VEA_000354	COG2205	protein histidine kinase activity
VEA_000354	COG0784	Response regulator, receiver
VEA_000356	COG5001	Diguanylate cyclase
VEA_000356	COG3300	MHYT domain
VEA_000358	COG0330	HflC and HflK could
VEA_000361	COG0517	IMP dehydrogenase activity
VEA_000361	COG4175	Glycine betaine
VEA_000362	COG4176	ABC-type proline glycine betaine transport system permease component
VEA_000365	COG1012	belongs to the aldehyde dehydrogenase family
VEA_000366	COG1309	transcriptional regulator
VEA_000368	COG3706	GGDEF domain
VEA_000368	COG0745	RESPONSE REGULATOR receiver
VEA_000369	COG1028	Short-chain dehydrogenase reductase Sdr
VEA_000372	COG1024	Enoyl-CoA hydratase
VEA_000373	COG1960	acyl-CoA dehydrogenase activity
VEA_000375	COG0183	Belongs to the thiolase family
VEA_000377	COG1960	acyl-CoA dehydrogenase activity
VEA_000378	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
VEA_000380	COG0439	Biotin carboxylase
VEA_000382	COG3437	response regulator, receiver
VEA_000382	COG3850	Histidine kinase
VEA_000382	COG2205	protein histidine kinase activity
VEA_000382	COG4999	Histidine kinase
VEA_000386	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VEA_000387	COG1271	oxidase subunit
VEA_000388	COG1294	oxidase, subunit
VEA_000390	COG0384	phenazine biosynthesis protein PhzF
VEA_000391	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VEA_000393	COG3527	Alpha-acetolactate decarboxylase
VEA_000396	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VEA_000409	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VEA_000410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VEA_000410	COG1263	PTS System
VEA_000411	COG1486	melibiose metabolic process
VEA_000412	COG2188	Transcriptional regulator
VEA_000413	COG1320	monovalent cation:proton antiporter activity
VEA_000414	COG2212	antiporter activity
VEA_000418	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VEA_000418	COG2111	Na H antiporter
VEA_000419	COG0589	response to stress
VEA_000420	COG4221	oxidoreductase activity
VEA_000421	COG0583	DNA-binding transcription factor activity
VEA_000423	COG2814	Major facilitator Superfamily
VEA_000427	COG3179	chitinase
VEA_000436	COG1522	sequence-specific DNA binding
VEA_000443	COG0515	serine threonine protein kinase
VEA_000448	COG3501	Rhs element vgr protein
VEA_000452	COG2885	chlorophyll binding
VEA_000457	COG0739	heme binding
VEA_000459	COG0674	pyruvate-flavodoxin oxidoreductase activity
VEA_000459	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
VEA_000460	COG1013	pyruvate-flavodoxin oxidoreductase activity
VEA_000463	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VEA_000470	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
VEA_000472	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VEA_000472	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VEA_000475	COG4989	oxidoreductase activity
VEA_000478	COG0038	chloride channel
VEA_000480	COG1914	H( )-stimulated, divalent metal cation uptake system
VEA_000483	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VEA_000488	COG2897	thiosulfate sulfurtransferase activity
VEA_000494	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
VEA_000495	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VEA_000496	COG0840	transmembrane signaling receptor activity
VEA_000497	COG2814	Major facilitator Superfamily
VEA_000498	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VEA_000500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VEA_000502	COG0840	transmembrane signaling receptor activity
VEA_000506	COG2195	Cleaves the N-terminal amino acid of tripeptides
VEA_000509	COG2197	response regulator
VEA_000510	COG3850	Histidine kinase
VEA_000511	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VEA_000513	COG0243	molybdopterin cofactor binding
VEA_000515	COG3005	denitrification pathway
VEA_000517	COG3243	poly(R)-hydroxyalkanoic acid synthase
VEA_000519	COG0183	Belongs to the thiolase family
VEA_000521	COG1280	lysine exporter protein (LysE YggA)
VEA_000523	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VEA_000524	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VEA_000536	COG2205	protein histidine kinase activity
VEA_000536	COG0784	Response regulator, receiver
VEA_000537	COG1879	ABC-type sugar transport system periplasmic component
VEA_000538	COG2827	Endonuclease containing a URI domain
VEA_000539	COG3132	Protein of unknown function, DUF480
VEA_000544	COG0784	Response regulator, receiver
VEA_000544	COG2205	protein histidine kinase activity
VEA_000544	COG5002	protein histidine kinase activity
VEA_000551	COG0583	DNA-binding transcription factor activity
VEA_000553	COG0531	amino acid
VEA_000556	COG2205	protein histidine kinase activity
VEA_000557	COG0745	RESPONSE REGULATOR receiver
VEA_000563	COG1566	PFAM secretion protein HlyD family protein
VEA_000564	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
VEA_000565	COG2239	Acts as a magnesium transporter
VEA_000566	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
VEA_000567	COG0402	S-adenosylhomocysteine deaminase activity
VEA_000568	COG1418	mRNA catabolic process
VEA_000570	COG2814	Major facilitator Superfamily
VEA_000572	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VEA_000576	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VEA_000579	COG0745	RESPONSE REGULATOR receiver
VEA_000580	COG2205	protein histidine kinase activity
VEA_000582	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VEA_000583	COG2194	sulfuric ester hydrolase activity
VEA_000588	COG4667	esterase of the alpha-beta hydrolase superfamily
VEA_000589	COG1741	Belongs to the pirin family
VEA_000590	COG1278	Cold shock
VEA_000592	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VEA_000593	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VEA_000593	COG0678	peroxiredoxin activity
VEA_000595	COG1686	Belongs to the peptidase S11 family
VEA_000596	COG0625	glutathione transferase activity
VEA_000597	COG1621	beta-fructofuranosidase activity
VEA_000598	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VEA_000599	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VEA_000599	COG1263	PTS System
VEA_000603	COG1028	Short-chain dehydrogenase reductase Sdr
VEA_000606	COG3746	phosphate-selective porin O and P
VEA_000611	COG2207	Transcriptional regulator
VEA_000611	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VEA_000612	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VEA_000619	COG0513	Belongs to the DEAD box helicase family
VEA_000621	COG0583	DNA-binding transcription factor activity
VEA_000624	COG1902	pentaerythritol trinitrate reductase activity
VEA_000625	COG1063	alcohol dehydrogenase
VEA_000627	COG1028	Short-chain dehydrogenase reductase Sdr
VEA_000628	COG2207	Transcriptional regulator
VEA_000629	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VEA_000630	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VEA_000631	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VEA_000632	COG0006	proline dipeptidase activity
VEA_000633	COG3608	succinylglutamate desuccinylase aspartoacylase
VEA_000634	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VEA_000635	COG1522	sequence-specific DNA binding
VEA_000636	COG1012	belongs to the aldehyde dehydrogenase family
VEA_000637	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VEA_000638	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
VEA_000639	COG2423	ornithine cyclodeaminase activity
VEA_000641	COG3122	Protein conserved in bacteria
VEA_000642	COG1280	lysine exporter protein (LysE YggA)
VEA_000644	COG0583	DNA-binding transcription factor activity
VEA_000646	COG0252	asparaginase activity
VEA_000647	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
VEA_000650	COG2197	response regulator
VEA_000651	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VEA_000654	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VEA_000659	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VEA_000665	COG3842	ATPase activity
VEA_000670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VEA_000677	COG0583	DNA-binding transcription factor activity
VEA_000679	COG4948	Mandelate Racemase Muconate Lactonizing
VEA_000680	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VEA_000685	COG1342	Belongs to the UPF0251 family
VEA_000686	COG4176	ABC-type proline glycine betaine transport system permease component
VEA_000687	COG3448	diguanylate cyclase activity
VEA_000687	COG4175	Glycine betaine
VEA_000688	COG3015	lipoprotein NlpE involved in copper resistance
VEA_000689	COG3713	MltA-interacting MipA family protein
VEA_000692	COG0583	DNA-binding transcription factor activity
VEA_000697	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VEA_000699	COG1335	isochorismatase
VEA_000701	COG1349	DNA-binding transcription factor activity
VEA_000702	COG0346	lactoylglutathione lyase activity
VEA_000703	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VEA_000703	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VEA_000705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VEA_000706	COG3537	Alpha-1,2-mannosidase
VEA_000707	COG3537	Alpha-1,2-mannosidase
VEA_000709	COG3537	Alpha-1,2-mannosidase
VEA_000710	COG3537	Alpha-1,2-mannosidase
VEA_000711	COG2070	2-Nitropropane dioxygenase
VEA_000712	COG0531	amino acid
VEA_000713	COG4302	ethanolamine ammonia-lyase activity
VEA_000714	COG4303	Ethanolamine ammonia lyase large subunit
VEA_000715	COG2207	Transcriptional regulator
VEA_000716	COG1309	transcriptional regulator
VEA_000722	COG0459	protein refolding
VEA_000723	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VEA_000724	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VEA_000726	COG1304	FMN binding
VEA_000730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VEA_000731	COG1256	bacterial-type flagellum assembly
VEA_000731	COG4786	Flagellar basal body rod
VEA_000733	COG1706	bacterial-type flagellum-dependent cell motility
VEA_000734	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VEA_000735	COG4786	Flagellar basal body rod
VEA_000736	COG4787	bacterial-type flagellum-dependent cell motility
VEA_000737	COG1749	Flagellar hook protein flgE
VEA_000738	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
VEA_000739	COG1558	bacterial-type flagellum-dependent cell motility
VEA_000740	COG1815	bacterial-type flagellum-dependent cell motility
VEA_000744	COG0741	lytic transglycosylase activity
VEA_000745	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
VEA_000749	COG1760	l-serine dehydratase
VEA_000754	COG0583	DNA-binding transcription factor activity
VEA_000756	COG2866	Carboxypeptidase
VEA_000757	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VEA_000760	COG2990	Protein conserved in bacteria
VEA_000765	COG3842	ATPase activity
VEA_000766	COG1840	ABC-type Fe3 transport system, periplasmic component
VEA_000769	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VEA_000770	COG1609	Transcriptional regulator
VEA_000776	COG3240	lipase activity
VEA_000778	COG2067	long-chain fatty acid transport protein
VEA_000779	COG3338	carbonate dehydratase activity
VEA_000780	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VEA_000783	COG1011	Hydrolase
VEA_000791	COG0110	maltose O-acetyltransferase activity
VEA_000792	COG1765	OsmC-like protein
VEA_000793	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VEA_000793	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VEA_000795	COG3046	protein related to deoxyribodipyrimidine photolyase
VEA_000796	COG0415	Belongs to the DNA photolyase family
VEA_000797	COG3706	GGDEF domain
VEA_000800	COG3706	GGDEF domain
VEA_000803	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VEA_000805	COG3033	Beta-eliminating lyase
VEA_000807	COG1271	oxidase subunit
VEA_000808	COG1294	oxidase, subunit
VEA_000810	COG0579	oxidoreductase
VEA_000814	COG3706	GGDEF domain
VEA_000816	COG4191	Histidine kinase
VEA_000824	COG0583	DNA-binding transcription factor activity
VEA_000825	COG0189	ligase activity
VEA_000826	COG0189	ligase activity
VEA_000826	COG4067	protein conserved in archaea
VEA_000828	COG1166	arginine decarboxylase activity
VEA_000829	COG0010	Belongs to the arginase family
VEA_000830	COG2814	Major facilitator Superfamily
VEA_000831	COG1770	oligopeptidase
VEA_000834	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VEA_000835	COG1121	(ABC) transporter
VEA_000836	COG0803	Belongs to the bacterial solute-binding protein 9 family
VEA_000845	COG0848	biopolymer transport protein
VEA_000846	COG0811	peptide transport
VEA_000847	COG0811	peptide transport
VEA_000850	COG2205	protein histidine kinase activity
VEA_000851	COG0745	RESPONSE REGULATOR receiver
VEA_000853	COG0584	glycerophosphoryl diester phosphodiesterase
VEA_000855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VEA_000860	COG1901	pseudouridine methyltransferase
VEA_000861	COG0312	modulator of DNA gyrase
VEA_000862	COG0312	modulator of DNA gyrase
VEA_000863	COG0351	phosphomethylpyrimidine kinase
VEA_000864	COG1116	anion transmembrane transporter activity
VEA_000865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VEA_000866	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
VEA_000867	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
VEA_000868	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
VEA_000869	COG0352	thiamine-phosphate diphosphorylase activity
VEA_000871	COG0243	molybdopterin cofactor binding
VEA_000872	COG3005	denitrification pathway
VEA_000873	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VEA_000874	COG1028	Short-chain dehydrogenase reductase Sdr
VEA_000877	COG0456	acetyltransferase
VEA_000881	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VEA_000882	COG1929	Belongs to the glycerate kinase type-1 family
VEA_000883	COG2610	gluconate transmembrane transporter activity
VEA_000884	COG3835	regulator
VEA_000889	COG0546	phosphoglycolate phosphatase activity
VEA_000892	COG0583	DNA-binding transcription factor activity
VEA_000894	COG0583	DNA-binding transcription factor activity
VEA_000896	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
VEA_000897	COG3408	Glycogen debranching enzyme
VEA_000897	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
VEA_000903	COG3047	cAMP biosynthetic process
VEA_000904	COG1357	PFAM Pentapeptide repeats (8 copies)
VEA_000908	COG1522	sequence-specific DNA binding
VEA_000911	COG2375	cellular response to nickel ion
VEA_000912	COG0823	Involved in the tonB-independent uptake of proteins
VEA_000913	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VEA_000917	COG0800	Aldolase
VEA_000918	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VEA_000921	COG1917	Cupin 2, conserved barrel domain protein
VEA_000923	COG1028	Short-chain dehydrogenase reductase Sdr
VEA_000924	COG1414	Transcriptional regulator
VEA_000927	COG0583	DNA-binding transcription factor activity
VEA_000928	COG2162	N-hydroxyarylamine O-acetyltransferase activity
VEA_000929	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
VEA_000932	COG2199	diguanylate cyclase activity
VEA_000934	COG0561	phosphatase activity
VEA_000935	COG0583	DNA-binding transcription factor activity
VEA_000939	COG0564	pseudouridine synthase activity
VEA_000940	COG0534	Mate efflux family protein
VEA_000943	COG3123	guanosine phosphorylase activity
VEA_000946	COG0596	Alpha beta hydrolase
VEA_000952	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
VEA_000954	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VEA_000955	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
VEA_000957	COG2259	Doxx family
VEA_000958	COG1741	Belongs to the pirin family
VEA_000962	COG0363	glucosamine-6-phosphate deaminase activity
VEA_000964	COG0786	glutamate:sodium symporter activity
VEA_000965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VEA_000966	COG1131	(ABC) transporter
VEA_000968	COG0786	glutamate:sodium symporter activity
VEA_000972	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VEA_000974	COG3279	Response regulator of the LytR AlgR family
VEA_000975	COG3275	phosphorelay sensor kinase activity
VEA_000979	COG1136	(ABC) transporter
VEA_000981	COG0772	Belongs to the SEDS family
VEA_000986	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
VEA_000986	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VEA_000988	COG0444	Belongs to the ABC transporter superfamily
VEA_000989	COG4608	Belongs to the ABC transporter superfamily
VEA_000995	COG1444	tRNA N-acetyltransferase activity
VEA_000999	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VEA_001000	COG1263	PTS System
VEA_001000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VEA_001001	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VEA_001004	COG4166	transmembrane transport
VEA_001014	COG0259	pyridoxamine-phosphate oxidase activity
VEA_001019	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VEA_001027	COG1132	(ABC) transporter
VEA_001029	COG2207	Transcriptional regulator
VEA_001034	COG2258	MOSC domain
VEA_001038	COG1595	DNA-templated transcription, initiation
VEA_001043	COG3634	alkyl hydroperoxide reductase activity
VEA_001044	COG0450	alkyl hydroperoxide reductase
VEA_001045	COG1846	Transcriptional regulator
VEA_001046	COG1764	response to oxidative stress
VEA_001050	COG1136	(ABC) transporter
VEA_001053	COG0463	Glycosyl transferase, family 2
VEA_001055	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VEA_001059	COG0745	RESPONSE REGULATOR receiver
VEA_001061	COG1653	transport
VEA_001062	COG0019	diaminopimelate decarboxylase activity
VEA_001063	COG4264	IucA IucC family
VEA_001064	COG2814	Major facilitator Superfamily
VEA_001068	COG4772	TonB-dependent receptor
VEA_001069	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
VEA_001070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VEA_001071	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VEA_001072	COG1120	ATPase activity
VEA_001073	COG0840	transmembrane signaling receptor activity
VEA_001074	COG0612	Peptidase, M16
VEA_001076	COG0739	heme binding
VEA_001084	COG4580	involved in the transport of maltose and maltodextrins
VEA_001088	COG2356	endonuclease I
VEA_001092	COG1982	Orn Lys Arg decarboxylase major
VEA_001093	COG0531	amino acid
VEA_001095	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
VEA_001096	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VEA_001097	COG1162	GTPase activity
VEA_001098	COG1263	PTS System
VEA_001098	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VEA_001099	COG1999	signal sequence binding
VEA_001102	COG2909	trisaccharide binding
VEA_001103	COG0058	SHG alpha-glucan phosphorylase activity
VEA_001104	COG1640	4-alpha-glucanotransferase
VEA_001105	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VEA_001106	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VEA_001107	COG0366	Alpha amylase catalytic
VEA_001110	COG3366	ferrous iron transmembrane transporter activity
VEA_001111	COG0700	Nucleoside recognition
VEA_001112	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VEA_001113	COG3339	Conserved Protein
VEA_001114	COG1301	dicarboxylic acid transport
VEA_001122	COG2095	MarC family integral membrane protein
VEA_001123	COG4667	esterase of the alpha-beta hydrolase superfamily
VEA_001124	COG3397	chitin binding
VEA_001125	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
VEA_001126	COG0415	Belongs to the DNA photolyase family
VEA_001131	COG1686	Belongs to the peptidase S11 family
VEA_001136	COG0583	DNA-binding transcription factor activity
VEA_001137	COG4628	conserved protein (DUF2132)
VEA_001140	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VEA_001141	COG0628	permease
VEA_001143	COG1566	PFAM secretion protein HlyD family protein
VEA_001150	COG2814	Major facilitator Superfamily
VEA_001152	COG0454	-acetyltransferase
VEA_001154	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
VEA_001155	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VEA_001165	COG1360	Flagellar Motor Protein
VEA_001166	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VEA_001167	COG1191	sigma factor activity
VEA_001168	COG1580	Controls the rotational direction of flagella during chemotaxis
VEA_001171	COG1516	flagellar protein fliS
VEA_001172	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VEA_001174	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VEA_001177	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
VEA_001179	COG1987	bacterial-type flagellum assembly
VEA_001184	COG2204	response regulator
VEA_001187	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VEA_001198	COG0346	lactoylglutathione lyase activity
VEA_001205	COG0745	RESPONSE REGULATOR receiver
VEA_001210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VEA_001211	COG5001	Diguanylate cyclase
VEA_001211	COG3300	MHYT domain
VEA_001212	COG0156	8-amino-7-oxononanoate synthase activity
VEA_001213	COG1063	alcohol dehydrogenase
VEA_001221	COG0668	transmembrane transport
VEA_001223	COG1304	FMN binding
VEA_001224	COG1620	l-lactate permease
VEA_001225	COG0583	DNA-binding transcription factor activity
VEA_001226	COG1505	serine-type exopeptidase activity
VEA_001228	COG4172	Belongs to the ABC transporter superfamily
VEA_001230	COG1067	ATP-dependent peptidase activity
VEA_001231	COG0840	transmembrane signaling receptor activity
VEA_001232	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VEA_001236	COG1247	-acetyltransferase
VEA_001237	COG0437	4 iron, 4 sulfur cluster binding
VEA_001238	COG0348	domain, Protein
VEA_001242	COG1122	ATPase activity
VEA_001243	COG4720	Psort location CytoplasmicMembrane, score
VEA_001244	COG1566	PFAM secretion protein HlyD family protein
VEA_001246	COG3706	GGDEF domain
VEA_001249	COG0813	purine-nucleoside phosphorylase activity
VEA_001250	COG3272	Protein of unknown function (DUF1722)
VEA_001251	COG0789	Transcriptional regulator
VEA_001252	COG0415	Belongs to the DNA photolyase family
VEA_001253	COG1388	LysM domain
VEA_001253	COG1376	ErfK ybiS ycfS ynhG family protein
VEA_001255	COG0513	Belongs to the DEAD box helicase family
VEA_001256	COG1770	oligopeptidase
VEA_001257	COG4771	TonB-dependent receptor
VEA_001262	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VEA_001263	COG0573	inorganic phosphate transmembrane transporter activity
VEA_001264	COG0581	inorganic phosphate transmembrane transporter activity
VEA_001265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VEA_001268	COG2304	oxidoreductase activity
VEA_001269	COG2304	oxidoreductase activity
VEA_001272	COG0714	Associated with various cellular activities
VEA_001273	COG0840	transmembrane signaling receptor activity
VEA_001275	COG2197	response regulator
VEA_001282	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
VEA_001283	COG1120	ATPase activity
VEA_001284	COG4774	siderophore transport
VEA_001285	COG1132	(ABC) transporter
VEA_001286	COG5002	protein histidine kinase activity
VEA_001288	COG0569	domain protein
VEA_001289	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VEA_001290	COG0583	DNA-binding transcription factor activity
VEA_001291	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VEA_001294	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VEA_001295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VEA_001297	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VEA_001298	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
VEA_001299	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VEA_001305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VEA_001305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VEA_001305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VEA_001306	COG2207	Transcriptional regulator
VEA_001308	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VEA_001309	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VEA_001310	COG2084	Dehydrogenase
VEA_001311	COG0753	catalase activity
VEA_001313	COG2130	NADP-dependent
VEA_001314	COG1309	transcriptional regulator
VEA_001326	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VEA_001327	COG3842	ATPase activity
VEA_001329	COG1175	transmembrane transport
VEA_001330	COG3833	ABC-type maltose transport systems, permease component
VEA_001336	COG2354	Protein conserved in bacteria
VEA_001337	COG0418	dihydroorotase activity
VEA_001339	COG0401	homolog of Blt101
VEA_001340	COG0633	Ferredoxin
VEA_001340	COG3217	Mosc domain protein beta barrel domain protein
VEA_001340	COG0633	Ferredoxin
VEA_001340	COG3217	Mosc domain protein beta barrel domain protein
VEA_001341	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VEA_001342	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VEA_001350	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VEA_001351	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VEA_001353	COG0848	biopolymer transport protein
VEA_001354	COG0811	peptide transport
VEA_001355	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VEA_001357	COG3721	Heme iron utilization protein
VEA_001358	COG0748	coenzyme F420 binding
VEA_001360	COG0784	Response regulator, receiver
VEA_001360	COG0835	chemotaxis
VEA_001361	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VEA_001369	COG0583	DNA-binding transcription factor activity
VEA_001370	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VEA_001372	COG4934	collagen metabolic process
VEA_001376	COG0366	Alpha amylase catalytic
VEA_001380	COG2249	NAD(P)H dehydrogenase (quinone) activity
VEA_001381	COG0589	response to stress
VEA_001382	COG0488	(ABC) transporter
VEA_001383	COG1505	serine-type exopeptidase activity
VEA_001385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VEA_001387	COG2067	long-chain fatty acid transport protein
VEA_001389	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VEA_001395	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VEA_001399	COG3383	formate dehydrogenase (NAD+) activity
VEA_001402	COG0842	Transport permease protein
VEA_001403	COG1131	(ABC) transporter
VEA_001405	COG2706	6-phosphogluconolactonase activity
VEA_001407	COG1881	PFAM PEBP family protein
VEA_001409	COG0798	PFAM Bile acid sodium symporter
VEA_001412	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VEA_001413	COG2213	PTS system mannitol-specific
VEA_001414	COG1063	alcohol dehydrogenase
VEA_001416	COG1072	(Pantothenic acid kinase))
VEA_001417	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
VEA_001420	COG0814	amino acid
VEA_001423	COG0840	transmembrane signaling receptor activity
VEA_001428	COG0739	heme binding
VEA_001429	COG5001	Diguanylate cyclase
VEA_001430	COG0583	DNA-binding transcription factor activity
VEA_001431	COG2814	Major facilitator Superfamily
VEA_001435	COG0697	spore germination
VEA_001438	COG0179	Fumarylacetoacetate (FAA) hydrolase
VEA_001441	COG2207	Transcriptional regulator
VEA_001442	COG1280	lysine exporter protein (LysE YggA)
VEA_001444	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VEA_001446	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
VEA_001447	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
VEA_001452	COG1612	heme a metabolic process
VEA_001453	COG0109	protoheme IX farnesyltransferase activity
VEA_001454	COG0545	Peptidyl-prolyl cis-trans isomerase
VEA_001456	COG2885	chlorophyll binding
VEA_001460	COG1278	Cold shock
VEA_001461	COG3036	rescue of stalled ribosome
VEA_001462	COG2199	diguanylate cyclase activity
VEA_001466	COG0577	efflux transmembrane transporter activity
VEA_001466	COG1136	(ABC) transporter
VEA_001468	COG0840	transmembrane signaling receptor activity
VEA_001469	COG0783	Belongs to the Dps family
VEA_001471	COG2133	pyrroloquinoline quinone binding
VEA_001472	COG1454	alcohol dehydrogenase
VEA_001473	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VEA_001478	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VEA_001479	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VEA_001480	COG3186	Phenylalanine-4-hydroxylase
VEA_001485	COG3530	Putative quorum-sensing-regulated virulence factor
VEA_001489	COG1404	Belongs to the peptidase S8 family
VEA_001494	COG0730	response to heat
VEA_001496	COG0513	Belongs to the DEAD box helicase family
VEA_001497	COG4628	conserved protein (DUF2132)
VEA_001499	COG0133	tryptophan synthase activity
VEA_001500	COG0557	exoribonuclease II activity
VEA_001501	COG1278	Cold shock
VEA_001503	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
VEA_001505	COG0523	cobalamin synthesis protein
VEA_001506	COG0513	Belongs to the DEAD box helicase family
VEA_001510	COG2200	EAL domain
VEA_001511	COG1119	ATPase activity
VEA_001512	COG0840	transmembrane signaling receptor activity
VEA_001517	COG1917	Cupin 2, conserved barrel domain protein
VEA_001517	COG1396	sequence-specific DNA binding
VEA_001521	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VEA_001524	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
VEA_001525	COG0513	Belongs to the DEAD box helicase family
VEA_001527	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VEA_001538	COG0247	lactate metabolic process
VEA_001538	COG0277	FAD linked oxidase domain protein
VEA_001541	COG1024	Enoyl-CoA hydratase
VEA_001542	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
VEA_001543	COG1960	acyl-CoA dehydrogenase activity
VEA_001545	COG0183	Belongs to the thiolase family
VEA_001548	COG1024	Enoyl-CoA hydratase
VEA_001549	COG1024	Enoyl-CoA hydratase
VEA_001551	COG1028	Short-chain dehydrogenase reductase Sdr
VEA_001553	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
VEA_001554	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
VEA_001555	COG1845	cytochrome c oxidase, subunit III
VEA_001556	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
VEA_001557	COG0109	protoheme IX farnesyltransferase activity
VEA_001563	COG1012	belongs to the aldehyde dehydrogenase family
VEA_001572	COG1126	abc transporter atp-binding protein
VEA_001573	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VEA_001574	COG4215	(ABC) transporter
VEA_001575	COG4160	amino acid transport
VEA_001578	COG2885	chlorophyll binding
VEA_001578	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
VEA_001588	COG0443	Heat shock 70 kDa protein
VEA_001589	COG2847	Copper chaperone PCu(A)C
VEA_001599	COG3706	GGDEF domain
VEA_001600	COG0814	amino acid
VEA_001602	COG0243	molybdopterin cofactor binding
VEA_001603	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VEA_001603	COG1648	precorrin-2 dehydrogenase activity
VEA_001606	COG3707	response regulator
VEA_001607	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
VEA_001607	COG1116	anion transmembrane transporter activity
VEA_001608	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VEA_001609	COG1116	anion transmembrane transporter activity
VEA_001610	COG4991	sh3 domain protein
VEA_001611	COG0405	Gamma-glutamyltransferase
VEA_001613	COG3267	Type II secretory pathway component ExeA
VEA_001613	COG3409	Peptidoglycan-binding domain 1 protein
VEA_001615	COG1968	undecaprenyl-diphosphatase activity
VEA_001616	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VEA_001617	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VEA_001618	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VEA_001619	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
VEA_001620	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VEA_001621	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VEA_001622	COG1610	YqeY-like protein
VEA_001623	COG0358	DNA primase activity
VEA_001624	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VEA_001632	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VEA_001632	COG2213	PTS system mannitol-specific
VEA_001634	COG3722	fumarate hydratase activity
VEA_001637	COG1461	Dihydroxyacetone kinase
VEA_001638	COG2376	Dihydroxyacetone kinase
VEA_001640	COG5002	protein histidine kinase activity
VEA_001643	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VEA_001644	COG1349	DNA-binding transcription factor activity
VEA_001645	COG0469	pyruvate kinase activity
VEA_001647	COG3706	GGDEF domain
VEA_001649	COG0028	Belongs to the TPP enzyme family
VEA_001650	COG1022	Amp-dependent synthetase and ligase
VEA_001651	COG0583	DNA-binding transcription factor activity
VEA_001656	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VEA_001657	COG0473	3-isopropylmalate dehydrogenase activity
VEA_001661	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VEA_001662	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VEA_001663	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VEA_001664	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VEA_001665	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VEA_001666	COG2967	ApaG domain
VEA_001667	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VEA_001670	COG2966	Psort location CytoplasmicMembrane, score
VEA_001671	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VEA_001673	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VEA_001674	COG0142	geranyltranstransferase activity
VEA_001682	COG1902	pentaerythritol trinitrate reductase activity
VEA_001683	COG0583	DNA-binding transcription factor activity
VEA_001684	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VEA_001685	COG1178	ABC-type Fe3 transport system permease component
VEA_001686	COG4143	(ABC) transporter
VEA_001687	COG0163	prenyltransferase activity
VEA_001688	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VEA_001689	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
VEA_001690	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VEA_001692	COG2105	PFAM AIG2 family protein
VEA_001693	COG2911	Protein conserved in bacteria
VEA_001694	COG0729	surface antigen
VEA_001695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VEA_001697	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VEA_001700	COG4181	ATPase activity
VEA_001704	COG0529	Catalyzes the synthesis of activated sulfate
VEA_001705	COG0471	metal ion transport
VEA_001705	COG3273	potassium ion transport
VEA_001706	COG2895	sulfate adenylyltransferase (ATP) activity
VEA_001707	COG0175	sulfate reduction
VEA_001708	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VEA_001708	COG1648	precorrin-2 dehydrogenase activity
VEA_001711	COG0513	Belongs to the DEAD box helicase family
VEA_001712	COG2153	protein acetylation
VEA_001714	COG0545	Peptidyl-prolyl cis-trans isomerase
VEA_001716	COG0203	ribosomal protein L17
VEA_001717	COG0202	RNA polymerase activity
VEA_001719	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VEA_001720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VEA_001722	COG0201	protein transport
VEA_001724	COG1841	ribosomal large subunit assembly
VEA_001727	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
VEA_001728	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VEA_001729	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VEA_001730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VEA_001731	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VEA_001733	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VEA_001734	COG0255	Belongs to the universal ribosomal protein uL29 family
VEA_001736	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VEA_001737	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VEA_001738	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VEA_001739	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VEA_001741	COG0088	Forms part of the polypeptide exit tunnel
VEA_001742	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VEA_001744	COG0254	rRNA binding
VEA_001745	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VEA_001746	COG1609	Transcriptional regulator
VEA_001748	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VEA_001749	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VEA_001750	COG1575	Belongs to the MenA family. Type 1 subfamily
VEA_001751	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VEA_001754	COG1494	fructose-1,6-bisphosphatase
VEA_001760	COG0149	triose-phosphate isomerase activity
VEA_001765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VEA_001768	COG0438	transferase activity, transferring glycosyl groups
VEA_001770	COG1216	Glycosyl transferase, family 2
VEA_001770	COG1442	glycosyl transferase family 8
VEA_001773	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VEA_001774	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VEA_001775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VEA_001776	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VEA_001777	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VEA_001785	COG0517	IMP dehydrogenase activity
VEA_001785	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VEA_001791	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VEA_001793	COG1560	Kdo2-lipid A biosynthetic process
VEA_001794	COG0859	PFAM glycosyl transferase family 9
VEA_001795	COG1519	Transferase
VEA_001797	COG1083	cytidylyl-transferase
VEA_001798	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
VEA_001800	COG2089	acid synthase
VEA_001801	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VEA_001802	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VEA_001803	COG1086	Polysaccharide biosynthesis protein
VEA_001805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VEA_001809	COG3642	lipopolysaccharide core region biosynthetic process
VEA_001810	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VEA_001811	COG0859	PFAM glycosyl transferase family 9
VEA_001812	COG0463	Glycosyl transferase, family 2
VEA_001821	COG2003	Belongs to the UPF0758 family
VEA_001823	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VEA_001824	COG1309	transcriptional regulator
VEA_001825	COG1560	Kdo2-lipid A biosynthetic process
VEA_001826	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VEA_001827	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VEA_001828	COG1561	YicC-like family, N-terminal region
VEA_001835	COG0328	RNA-DNA hybrid ribonuclease activity
VEA_001836	COG2003	Belongs to the UPF0758 family
VEA_001848	COG5001	Diguanylate cyclase
VEA_001850	COG4608	Belongs to the ABC transporter superfamily
VEA_001851	COG0444	Belongs to the ABC transporter superfamily
VEA_001852	COG0747	negative chemotaxis
VEA_001853	COG4239	(ABC) transporter, permease
VEA_001854	COG4174	ABC transporter (Permease)
VEA_001858	COG0811	peptide transport
VEA_001859	COG0848	biopolymer transport protein
VEA_001862	COG0194	GDP metabolic process
VEA_001863	COG1758	RNA polymerase activity
VEA_001864	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VEA_001865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VEA_001866	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VEA_001868	COG2233	PERMEase
VEA_001869	COG2205	protein histidine kinase activity
VEA_001870	COG0745	RESPONSE REGULATOR receiver
VEA_001872	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VEA_001874	COG2183	response to ionizing radiation
VEA_001876	COG0596	Alpha beta hydrolase
VEA_001878	COG1040	competence protein
VEA_001879	COG0316	Belongs to the HesB IscA family
VEA_001879	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
VEA_001880	COG0494	nUDIX hydrolase
VEA_001881	COG1218	3'(2'),5'-bisphosphate nucleotidase
VEA_001883	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VEA_001884	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VEA_001885	COG3156	type II secretion system protein K
VEA_001886	COG4795	General secretion pathway protein
VEA_001887	COG2165	general secretion pathway protein
VEA_001888	COG2165	general secretion pathway protein
VEA_001889	COG2165	general secretion pathway protein
VEA_001890	COG1459	type II secretion system
VEA_001891	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VEA_001893	COG3031	protein transport across the cell outer membrane
VEA_001894	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VEA_001895	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VEA_001896	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
VEA_001898	COG0456	acetyltransferase
VEA_001899	COG1490	D-aminoacyl-tRNA deacylase activity
VEA_001900	COG1295	ribonuclease BN
VEA_001905	COG0174	glutamine synthetase
VEA_001907	COG3852	Histidine kinase
VEA_001908	COG2204	response regulator
VEA_001910	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VEA_001911	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VEA_001916	COG0218	Necessary for normal cell division and for the maintenance of normal septation
VEA_001917	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VEA_001917	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VEA_001918	COG0456	acetyltransferase
VEA_001920	COG0084	hydrolase, TatD family'
VEA_001922	COG0805	protein transport
VEA_001925	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
VEA_001926	COG3165	ubiquinone biosynthetic process from chorismate
VEA_001927	COG2226	methyltransferase
VEA_001928	COG1322	Protein conserved in bacteria
VEA_001931	COG0628	permease
VEA_001937	COG1597	lipid kinase activity
VEA_001943	COG2081	HI0933 family
VEA_001945	COG1528	Iron-storage protein
VEA_001946	COG0589	response to stress
VEA_001947	COG0697	spore germination
VEA_001949	COG0742	ribosomal rna small subunit methyltransferase
VEA_001950	COG5002	protein histidine kinase activity
VEA_001950	COG5001	Diguanylate cyclase
VEA_001951	COG1522	sequence-specific DNA binding
VEA_001953	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VEA_001954	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VEA_001955	COG0583	DNA-binding transcription factor activity
VEA_001956	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
VEA_001957	COG0800	Aldolase
VEA_001958	COG2610	gluconate transmembrane transporter activity
VEA_001959	COG3265	gluconokinase activity
VEA_001960	COG0129	dihydroxy-acid dehydratase activity
VEA_001963	COG0583	DNA-binding transcription factor activity
VEA_001964	COG1609	Transcriptional regulator
VEA_001972	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VEA_001974	COG4166	transmembrane transport
VEA_001975	COG4172	Belongs to the ABC transporter superfamily
VEA_001980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VEA_001981	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VEA_001982	COG2960	long-chain fatty acid transporting porin activity
VEA_001983	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VEA_001984	COG0583	DNA-binding transcription factor activity
VEA_001986	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VEA_001987	COG1739	Uncharacterized protein family UPF0029
VEA_001989	COG0183	Belongs to the thiolase family
VEA_001990	COG0604	alcohol dehydrogenase
VEA_001993	COG0425	Belongs to the sulfur carrier protein TusA family
VEA_001996	COG2119	membrane
VEA_002001	COG0366	Alpha amylase catalytic
VEA_002002	COG3977	Valine--pyruvate aminotransferase
VEA_002003	COG0071	Belongs to the small heat shock protein (HSP20) family
VEA_002006	COG0187	DNA topoisomerase II activity
VEA_002008	COG0592	DNA-directed DNA polymerase activity
VEA_002009	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VEA_002012	COG1126	abc transporter atp-binding protein
VEA_002014	COG0594	ribonuclease P activity
VEA_002015	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
VEA_002016	COG0706	membrane insertase activity
VEA_002018	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VEA_002019	COG0445	tRNA wobble uridine modification
VEA_002020	COG0357	Ribosomal RNA small subunit methyltransferase G
VEA_002021	COG1192	Involved in chromosome partitioning
VEA_002022	COG1475	DNA binding
VEA_002023	COG3312	ion transport
VEA_002024	COG0356	it plays a direct role in the translocation of protons across the membrane
VEA_002026	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VEA_002027	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VEA_002028	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VEA_002029	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VEA_002030	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VEA_002031	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VEA_002033	COG0765	amino acid transport
VEA_002035	COG2814	Major facilitator Superfamily
VEA_002036	COG0583	DNA-binding transcription factor activity
VEA_002038	COG0129	dihydroxy-acid dehydratase activity
VEA_002039	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VEA_002040	COG3978	acetolactate synthase activity
VEA_002042	COG0606	chelatase, subunit chli
VEA_002044	COG0204	Acyl-transferase
VEA_002045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VEA_002046	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VEA_002048	COG3084	Protein conserved in bacteria
VEA_002050	COG4326	sporulation control protein
VEA_002051	COG1272	protein, Hemolysin III
VEA_002053	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VEA_002054	COG0569	domain protein
VEA_002055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VEA_002055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VEA_002056	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VEA_002057	COG0242	peptide deformylase activity
VEA_002059	COG0758	DNA mediated transformation
VEA_002060	COG2922	Belongs to the Smg family
VEA_002062	COG0551	DNA topoisomerase type I activity
VEA_002063	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VEA_002064	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VEA_002065	COG0009	L-threonylcarbamoyladenylate synthase
VEA_002066	COG0408	coproporphyrinogen oxidase activity
VEA_002067	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VEA_002069	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VEA_002070	COG2132	Multicopper oxidase
VEA_002071	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VEA_002074	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VEA_002075	COG2104	thiamine diphosphate biosynthetic process
VEA_002078	COG0006	proline dipeptidase activity
VEA_002078	COG0006	proline dipeptidase activity
VEA_002084	COG3220	belongs to the UPF0276 family
VEA_002086	COG0210	DNA helicase
VEA_002088	COG0405	Gamma-glutamyltransferase
VEA_002089	COG1280	lysine exporter protein (LysE YggA)
VEA_002091	COG2962	Rard protein
VEA_002092	COG0514	ATP-dependent DNA helicase (RecQ)
VEA_002094	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VEA_002095	COG0248	Ppx GppA phosphatase
VEA_002096	COG0513	Belongs to the DEAD box helicase family
VEA_002097	COG3118	belongs to the thioredoxin family
VEA_002098	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
VEA_002100	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VEA_002103	COG3071	HemY protein
VEA_002104	COG2959	enzyme of heme biosynthesis
VEA_002105	COG1587	Uroporphyrinogen-III synthase
VEA_002106	COG0181	hydroxymethylbilane synthase activity
VEA_002107	COG3072	Adenylate cyclase
VEA_002108	COG1965	Belongs to the frataxin family
VEA_002110	COG0019	diaminopimelate decarboxylase activity
VEA_002111	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VEA_002113	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VEA_002114	COG1011	Hydrolase
VEA_002115	COG2199	diguanylate cyclase activity
VEA_002115	COG3287	FIST C domain
VEA_002115	COG2200	EAL domain
VEA_002120	COG0561	phosphatase activity
VEA_002122	COG2267	carboxylic ester hydrolase activity
VEA_002123	COG1280	lysine exporter protein (LysE YggA)
VEA_002124	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VEA_002125	COG0640	Transcriptional regulator
VEA_002126	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VEA_002135	COG2095	MarC family integral membrane protein
VEA_002137	COG0742	ribosomal rna small subunit methyltransferase
VEA_002138	COG0552	protein localization to endoplasmic reticulum
VEA_002139	COG2884	Cell division ATP-binding protein ftsE
VEA_002140	COG2177	Part of the ABC transporter FtsEX involved in
VEA_002142	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VEA_002143	COG0705	Rhomboid family
VEA_002144	COG1580	Controls the rotational direction of flagella during chemotaxis
VEA_002145	COG3161	chorismate lyase activity
VEA_002146	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VEA_002147	COG2937	Belongs to the GPAT DAPAT family
VEA_002149	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VEA_002150	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
VEA_002151	COG0534	Mate efflux family protein
VEA_002152	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VEA_002156	COG4206	TonB-dependent receptor
VEA_002160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VEA_002162	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VEA_002163	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
VEA_002163	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
VEA_002166	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VEA_002167	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VEA_002168	COG0250	Participates in transcription elongation, termination and antitermination
VEA_002171	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VEA_002172	COG0222	ribosome binding
VEA_002173	COG0085	RNA polymerase activity
VEA_002174	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VEA_002175	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VEA_002176	COG2816	NAD+ diphosphatase activity
VEA_002177	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VEA_002178	COG1573	uracil-dna glycosylase
VEA_002180	COG3068	Protein conserved in bacteria
VEA_002181	COG1253	flavin adenine dinucleotide binding
VEA_002184	COG0151	Belongs to the GarS family
VEA_002185	COG0138	bifunctional purine biosynthesis protein purh
VEA_002186	COG0789	Transcriptional regulator
VEA_002187	COG3710	Transcriptional regulator
VEA_002188	COG0531	amino acid
VEA_002189	COG1982	Orn Lys Arg decarboxylase major
VEA_002191	COG0488	(ABC) transporter
VEA_002193	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VEA_002194	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VEA_002195	COG2264	protein methyltransferase activity
VEA_002196	COG0439	Biotin carboxylase
VEA_002197	COG0511	ligase activity, forming carbon-carbon bonds
VEA_002198	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VEA_002199	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VEA_002202	COG2814	Major facilitator Superfamily
VEA_002207	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VEA_002210	COG3263	regulation of cellular component size
VEA_002212	COG4232	protein-disulfide reductase activity
VEA_002213	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VEA_002214	COG1027	Aspartate ammonia-lyase
VEA_002216	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VEA_002218	COG2205	protein histidine kinase activity
VEA_002219	COG0745	RESPONSE REGULATOR receiver
VEA_002220	COG3678	ATP-independent chaperone mediated protein folding
VEA_002221	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VEA_002222	COG0205	6-phosphofructokinase activity
VEA_002223	COG0534	Mate efflux family protein
VEA_002224	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VEA_002225	COG0459	protein refolding
VEA_002230	COG1285	pathogenesis
VEA_002231	COG1509	lysine 2,3-aminomutase activity
VEA_002235	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VEA_002236	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VEA_002237	COG1053	succinate dehydrogenase
VEA_002238	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VEA_002242	COG4942	peptidase
VEA_002243	COG1045	serine acetyltransferase
VEA_002244	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VEA_002245	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VEA_002246	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VEA_002247	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VEA_002249	COG3273	potassium ion transport
VEA_002249	COG0471	metal ion transport
VEA_002250	COG0688	phosphatidylethanolamine metabolic process
VEA_002251	COG1162	GTPase activity
VEA_002252	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VEA_002253	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VEA_002255	COG0802	atpase or kinase
VEA_002257	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VEA_002258	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VEA_002260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VEA_002261	COG0330	HflC and HflK could
VEA_002262	COG0330	HflC and HflK could
VEA_002263	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VEA_002264	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VEA_002265	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VEA_002266	COG1017	nitric oxide dioxygenase activity
VEA_002266	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VEA_002267	COG1959	2 iron, 2 sulfur cluster binding
VEA_002268	COG0557	exoribonuclease II activity
VEA_002269	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VEA_002270	COG0546	phosphoglycolate phosphatase activity
VEA_002271	COG0180	Tryptophanyl-tRNA synthetase
VEA_002275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VEA_002279	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VEA_002280	COG3954	Phosphoribulokinase
VEA_002281	COG3089	Belongs to the UPF0270 family
VEA_002282	COG0429	hydrolase of the alpha beta-hydrolase fold
VEA_002284	COG0488	(ABC) transporter
VEA_002285	COG2249	NAD(P)H dehydrogenase (quinone) activity
VEA_002288	COG1047	Peptidyl-prolyl cis-trans
VEA_002289	COG1446	asparaginase
VEA_002292	COG0545	Peptidyl-prolyl cis-trans isomerase
VEA_002293	COG2964	Protein conserved in bacteria
VEA_002294	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VEA_002295	COG2923	Belongs to the DsrF TusC family
VEA_002296	COG2168	tRNA wobble position uridine thiolation
VEA_002299	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VEA_002300	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VEA_002303	COG0281	malic enzyme
VEA_002306	COG0626	cystathionine gamma-synthase activity
VEA_002307	COG0460	homoserine dehydrogenase
VEA_002307	COG0527	aspartate kinase activity
VEA_002308	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VEA_002310	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VEA_002312	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VEA_002314	COG0137	argininosuccinate synthase activity
VEA_002315	COG0165	Argininosuccinate lyase
VEA_002315	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VEA_002319	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VEA_002319	COG0678	peroxiredoxin activity
VEA_002321	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VEA_002327	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VEA_002328	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VEA_002330	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VEA_002331	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VEA_002332	COG0360	Binds together with S18 to 16S ribosomal RNA
VEA_002333	COG2965	DNA replication, synthesis of RNA primer
VEA_002337	COG0305	Participates in initiation and elongation during chromosome replication
VEA_002338	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VEA_002339	COG0432	Pfam Uncharacterised protein family UPF0047
VEA_002341	COG0166	Belongs to the GPI family
VEA_002343	COG0735	belongs to the Fur family
VEA_002346	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VEA_002350	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VEA_002351	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VEA_002352	COG0175	sulfate reduction
VEA_002355	COG0646	methionine synthase
VEA_002355	COG1410	methionine synthase
VEA_002356	COG0527	aspartate kinase activity
VEA_002358	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VEA_002360	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VEA_002363	COG0629	single-stranded DNA binding
VEA_002364	COG2199	diguanylate cyclase activity
VEA_002364	COG2200	EAL domain
VEA_002368	COG1450	Type ii and iii secretion system protein
VEA_002369	COG3409	Peptidoglycan-binding domain 1 protein
VEA_002369	COG3267	Type II secretory pathway component ExeA
VEA_002371	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VEA_002372	COG1459	type II secretion system
VEA_002383	COG1077	Cell shape determining protein MreB Mrl
VEA_002384	COG1792	Involved in formation and maintenance of cell shape
VEA_002385	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VEA_002386	COG0424	maF-like protein
VEA_002387	COG1530	ribonuclease E activity
VEA_002388	COG3164	Protein of unknown function
VEA_002389	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VEA_002390	COG0312	modulator of DNA gyrase
VEA_002391	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VEA_002392	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VEA_002394	COG0564	pseudouridine synthase activity
VEA_002395	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VEA_002396	COG3028	Belongs to the UPF0307 family
VEA_002397	COG0312	modulator of DNA gyrase
VEA_002398	COG2239	Acts as a magnesium transporter
VEA_002399	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VEA_002400	COG1660	Displays ATPase and GTPase activities
VEA_002401	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VEA_002402	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VEA_002404	COG1137	ATPase activity
VEA_002405	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VEA_002409	COG1127	ABC transporter
VEA_002410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VEA_002411	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VEA_002412	COG2854	intermembrane phospholipid transfer
VEA_002414	COG5007	Belongs to the BolA IbaG family
VEA_002416	COG0204	Acyl-transferase
VEA_002417	COG0251	oxidation-reduction process
VEA_002418	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
VEA_002419	COG0540	Belongs to the ATCase OTCase family
VEA_002426	COG0525	valine-tRNA ligase activity
VEA_002427	COG2927	DNA polymerase III (CHI subunit)
VEA_002429	COG0795	lipopolysaccharide-transporting ATPase activity
VEA_002430	COG0795	lipopolysaccharide-transporting ATPase activity
VEA_002432	COG4325	translation initiation factor activity
VEA_002433	COG1028	Short-chain dehydrogenase reductase Sdr
VEA_002434	COG0726	polysaccharide deacetylase
VEA_002436	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VEA_002437	COG1447	Phosphotransferase system cellobiose-specific component IIA
VEA_002438	COG1486	melibiose metabolic process
VEA_002439	COG3394	polysaccharide catabolic process
VEA_002441	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VEA_002442	COG1012	belongs to the aldehyde dehydrogenase family
VEA_002445	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VEA_002447	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VEA_002449	COG2066	Belongs to the glutaminase family
VEA_002450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VEA_002451	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VEA_002453	COG1872	DUF167
VEA_002454	COG0762	integral membrane protein
VEA_002455	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VEA_002457	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VEA_002460	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VEA_002461	COG1678	Uncharacterized ACR, COG1678
VEA_002462	COG0189	ligase activity
VEA_002463	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VEA_002464	COG2356	endonuclease I
VEA_002467	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VEA_002468	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VEA_002469	COG0583	DNA-binding transcription factor activity
VEA_002470	COG4771	TonB-dependent receptor
VEA_002471	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VEA_002472	COG0126	phosphoglycerate kinase activity
VEA_002473	COG0191	fructose-bisphosphate aldolase activity
VEA_002474	COG0668	transmembrane transport
VEA_002477	COG0583	DNA-binding transcription factor activity
VEA_002479	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VEA_002480	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VEA_002481	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VEA_002482	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VEA_002483	COG3079	Belongs to the UPF0149 family
VEA_002484	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VEA_002485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VEA_002488	COG0354	folic acid binding
VEA_002489	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VEA_002490	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VEA_002491	COG1595	DNA-templated transcription, initiation
VEA_002494	COG3086	response to oxidative stress
VEA_002495	COG0481	GTPase activity
VEA_002496	COG0681	Belongs to the peptidase S26 family
VEA_002498	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VEA_002499	COG1381	Involved in DNA repair and RecF pathway recombination
VEA_002500	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VEA_002501	COG0736	holo-[acyl-carrier-protein] synthase activity
VEA_002503	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VEA_002504	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VEA_002505	COG3956	TIGRFAM MazG family protein
VEA_002506	COG0504	CTP synthase activity
VEA_002507	COG0148	phosphopyruvate hydratase activity
VEA_002509	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VEA_002510	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VEA_002513	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VEA_002514	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VEA_002516	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VEA_002517	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VEA_002518	COG1546	Belongs to the CinA family
VEA_002519	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VEA_002520	COG2137	regulation of response to DNA damage stimulus
VEA_002521	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VEA_002522	COG0527	aspartate kinase activity
VEA_002525	COG0511	ligase activity, forming carbon-carbon bonds
VEA_002525	COG5016	pyruvate
VEA_002526	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VEA_002528	COG1238	metal cluster binding
VEA_002529	COG0612	Peptidase, M16
VEA_002532	COG1854	S-ribosylhomocysteine lyase activity
VEA_002533	COG4536	flavin adenine dinucleotide binding
VEA_002534	COG4137	Cytochrome C assembly protein
VEA_002535	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VEA_002536	COG0228	four-way junction DNA binding
VEA_002537	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VEA_002540	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
VEA_002541	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VEA_002542	COG0237	dephospho-CoA kinase activity
VEA_002544	COG1459	type II secretion system
VEA_002545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VEA_002546	COG4969	Belongs to the N-Me-Phe pilin family
VEA_002547	COG0157	Belongs to the NadC ModD family
VEA_002549	COG2186	Transcriptional regulator
VEA_002550	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VEA_002551	COG0508	dehydrogenase complex catalyzes the overall conversion of
VEA_002552	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VEA_002555	COG0288	reversible hydration of carbon dioxide
VEA_002556	COG0659	secondary active sulfate transmembrane transporter activity
VEA_002557	COG1131	(ABC) transporter
VEA_002558	COG0842	Transport permease protein
VEA_002559	COG1560	Kdo2-lipid A biosynthetic process
VEA_002560	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VEA_002561	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VEA_002562	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VEA_002564	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VEA_002565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VEA_002566	COG1489	DNA binding
VEA_002567	COG1643	Atp-dependent helicase
VEA_002568	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VEA_002569	COG1752	Esterase of the alpha-beta hydrolase superfamily
VEA_002570	COG1049	propionate catabolic process, 2-methylcitrate cycle
VEA_002571	COG3112	Uncharacterised protein family (UPF0231)
VEA_002572	COG0347	Belongs to the P(II) protein family
VEA_002573	COG0004	ammonium transporteR
VEA_002574	COG1840	ABC-type Fe3 transport system, periplasmic component
VEA_002576	COG3842	ATPase activity
VEA_002577	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VEA_002580	COG2971	BadF BadG BcrA BcrD
VEA_002582	COG4608	Belongs to the ABC transporter superfamily
VEA_002583	COG0444	Belongs to the ABC transporter superfamily
VEA_002586	COG0747	negative chemotaxis
VEA_002589	COG0628	permease
VEA_002591	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VEA_002595	COG0739	heme binding
VEA_002596	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VEA_002598	COG2027	D-alanyl-D-alanine carboxypeptidase
VEA_002599	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VEA_002600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VEA_002601	COG1534	Rna-binding protein
VEA_002602	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VEA_002603	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VEA_002604	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VEA_002605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VEA_002606	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VEA_002607	COG0779	Required for maturation of 30S ribosomal subunits
VEA_002608	COG0195	Participates in both transcription termination and antitermination
VEA_002609	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VEA_002610	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VEA_002611	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
VEA_002612	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VEA_002613	COG1185	polyribonucleotide nucleotidyltransferase activity
VEA_002616	COG0534	Mate efflux family protein
VEA_002621	COG3153	acetyltransferase
VEA_002625	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
VEA_002627	COG0084	hydrolase, TatD family'
VEA_002628	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VEA_002630	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VEA_002631	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VEA_002632	COG0813	purine-nucleoside phosphorylase activity
VEA_002634	COG0560	Phosphoserine phosphatase
VEA_002636	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VEA_002637	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VEA_002638	COG0583	DNA-binding transcription factor activity
VEA_002639	COG1022	Amp-dependent synthetase and ligase
VEA_002640	COG2169	Transcriptional regulator
VEA_002644	COG4964	Belongs to the GSP D family
VEA_002655	COG0583	DNA-binding transcription factor activity
VEA_002656	COG0531	amino acid
VEA_002657	COG2731	YhcH YjgK YiaL family protein
VEA_002658	COG3250	beta-galactosidase activity
VEA_002659	COG1609	Transcriptional regulator
VEA_002660	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VEA_002661	COG1085	galactose-1-phosphate uridylyltransferase
VEA_002662	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VEA_002663	COG2017	converts alpha-aldose to the beta-anomer
VEA_002666	COG2211	Major facilitator Superfamily
VEA_002667	COG1609	Transcriptional regulator
VEA_002668	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VEA_002673	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VEA_002674	COG1349	DNA-binding transcription factor activity
VEA_002675	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
VEA_002676	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VEA_002677	COG2271	Major facilitator Superfamily
VEA_002678	COG0584	glycerophosphoryl diester phosphodiesterase
VEA_002679	COG2171	N-acyltransferase activity
VEA_002680	COG3141	response to X-ray
VEA_002684	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VEA_002685	COG1074	ATP-dependent DNA helicase activity
VEA_002686	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VEA_002688	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VEA_002688	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VEA_002690	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VEA_002691	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VEA_002692	COG2166	iron-sulfur cluster assembly
VEA_002693	COG3706	GGDEF domain
VEA_002694	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VEA_002695	COG0693	protein deglycase activity
VEA_002696	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VEA_002700	COG1595	DNA-templated transcription, initiation
VEA_002704	COG3056	Lipoprotein
VEA_002705	COG2813	Specifically methylates the guanine in position
VEA_002706	COG0271	Belongs to the BolA IbaG family
VEA_002707	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VEA_002708	COG1805	sodium ion transport
VEA_002709	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VEA_002710	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VEA_002711	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VEA_002712	COG2871	sodium ion transport
VEA_002713	COG1477	protein flavinylation
VEA_002716	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VEA_002717	COG0514	ATP-dependent DNA helicase (RecQ)
VEA_002721	COG0733	neurotransmitter:sodium symporter activity
VEA_002725	COG0442	prolyl-tRNA aminoacylation
VEA_002726	COG1720	tRNA m6t6A37 methyltransferase activity
VEA_002727	COG0254	rRNA binding
VEA_002729	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VEA_002734	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VEA_002735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VEA_002742	COG0564	pseudouridine synthase activity
VEA_002744	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VEA_002745	COG0024	Methionine aminopeptidase
VEA_002746	COG0052	Belongs to the universal ribosomal protein uS2 family
VEA_002747	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VEA_002748	COG0528	UMP kinase activity
VEA_002749	COG0233	cytoplasmic translational termination
VEA_002750	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VEA_002751	COG0575	Belongs to the CDS family
VEA_002752	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VEA_002753	COG0750	zinc metalloprotease
VEA_002755	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VEA_002756	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VEA_002759	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VEA_002760	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VEA_002762	COG0587	DNA-directed DNA polymerase activity
VEA_002763	COG0825	malonyl-CoA metabolic process
VEA_002766	COG0347	Belongs to the P(II) protein family
VEA_002767	COG3021	interspecies interaction between organisms
VEA_002769	COG0741	lytic transglycosylase activity
VEA_002769	COG1388	LysM domain
VEA_002770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VEA_002771	COG2226	methyltransferase
VEA_002772	COG0328	RNA-DNA hybrid ribonuclease activity
VEA_002773	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VEA_002777	COG1960	acyl-CoA dehydrogenase activity
VEA_002778	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VEA_002779	COG0121	glutamine amidotransferase
VEA_002780	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VEA_002781	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VEA_002782	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VEA_002783	COG2233	PERMEase
VEA_002787	COG1393	Belongs to the ArsC family
VEA_002788	COG4783	chaperone-mediated protein folding
VEA_002791	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VEA_002793	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VEA_002797	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VEA_002798	COG1393	Belongs to the ArsC family
VEA_002803	COG2837	iron assimilation
VEA_002804	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VEA_002805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VEA_002806	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VEA_002807	COG1334	flagellar protein FlaG
VEA_002808	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VEA_002810	COG1516	flagellar protein fliS
VEA_002812	COG4191	Histidine kinase
VEA_002813	COG2204	response regulator
VEA_002814	COG1677	Flagellar hook-basal body complex protein FliE
VEA_002816	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VEA_002826	COG1987	bacterial-type flagellum assembly
VEA_002827	COG1684	flagellar biosynthetic protein fliR
VEA_002831	COG0455	bacterial-type flagellum organization
VEA_002834	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VEA_002835	COG0643	Histidine kinase
VEA_002835	COG2198	Histidine kinase
VEA_002836	COG2201	protein-glutamate methylesterase activity
VEA_002837	COG1192	Involved in chromosome partitioning
VEA_002839	COG0835	chemotaxis
VEA_002841	COG4133	protoheme IX ABC transporter activity
VEA_002842	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VEA_002843	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VEA_002844	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VEA_002845	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VEA_002846	COG1138	Cytochrome C-type biogenesis protein
VEA_002847	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VEA_002849	COG3088	subunit of a heme lyase
VEA_002849	COG4235	cytochrome complex assembly
VEA_002851	COG2067	long-chain fatty acid transport protein
VEA_002856	COG0183	Belongs to the thiolase family
VEA_002857	COG1250	3-hydroxyacyl-CoA dehydrogenase
VEA_002857	COG1024	Enoyl-CoA hydratase
VEA_002860	COG2062	phosphohistidine phosphatase, SixA
VEA_002861	COG2840	Smr protein MutS2
VEA_002862	COG2890	protein-(glutamine-N5) methyltransferase activity
VEA_002864	COG2860	membrane
VEA_002866	COG3101	peptidyl-lysine hydroxylation
VEA_002868	COG0431	NADPH-dependent FMN reductase
VEA_002869	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VEA_002869	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VEA_002870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VEA_002871	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VEA_002872	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VEA_002874	COG0101	tRNA pseudouridine synthase activity
VEA_002875	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VEA_002876	COG0285	dihydrofolate synthase activity
VEA_002877	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VEA_002878	COG1286	toxin biosynthetic process
VEA_002879	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VEA_002880	COG0583	DNA-binding transcription factor activity
VEA_002881	COG0745	RESPONSE REGULATOR receiver
VEA_002884	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VEA_002886	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VEA_002890	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VEA_002891	COG0814	amino acid
VEA_002892	COG0251	oxidation-reduction process
VEA_002893	COG3681	Belongs to the UPF0597 family
VEA_002896	COG2261	transglycosylase associated protein
VEA_002897	COG2983	Belongs to the UPF0260 family
VEA_002898	COG0668	transmembrane transport
VEA_002899	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
VEA_002900	COG0346	lactoylglutathione lyase activity
VEA_002902	COG1785	Belongs to the alkaline phosphatase family
VEA_002905	COG2226	methyltransferase
VEA_002908	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VEA_002909	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VEA_002911	COG3139	Protein of unknown function (DUF1315)
VEA_002912	COG0252	asparaginase activity
VEA_002913	COG0616	signal peptide processing
VEA_002914	COG0446	pyridine nucleotide-disulphide oxidoreductase
VEA_002914	COG1902	pentaerythritol trinitrate reductase activity
VEA_002916	COG0778	Nitroreductase
VEA_002917	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VEA_002921	COG0123	including yeast histone deacetylase and acetoin utilization protein
VEA_002923	COG3082	Protein of unknown function (DUF1414)
VEA_002924	COG3081	Nucleoid-associated protein
VEA_002927	COG1757	Na H antiporter
VEA_002928	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VEA_002929	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VEA_002930	COG2095	MarC family integral membrane protein
VEA_002931	COG1454	alcohol dehydrogenase
VEA_002931	COG1012	belongs to the aldehyde dehydrogenase family
VEA_002935	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VEA_002937	COG2056	Na+-H+ antiporter family
VEA_002938	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VEA_002940	COG2885	chlorophyll binding
VEA_002942	COG0346	lactoylglutathione lyase activity
VEA_002943	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VEA_002944	COG4660	Part of a membrane complex involved in electron transport
VEA_002945	COG4659	FMN binding
VEA_002946	COG4658	electron transport chain
VEA_002947	COG4656	Part of a membrane complex involved in electron transport
VEA_002948	COG2878	Part of a membrane complex involved in electron transport
VEA_002949	COG4657	Part of a membrane complex involved in electron transport
VEA_002950	COG0556	nucleotide-excision repair
VEA_002951	COG2204	response regulator
VEA_002952	COG2198	Histidine kinase
VEA_002953	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VEA_002954	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VEA_002955	COG0521	Mo-molybdopterin cofactor biosynthetic process
VEA_002956	COG0315	cyclic pyranopterin monophosphate synthase activity
VEA_002957	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VEA_002958	COG0314	molybdopterin synthase activity
VEA_002960	COG0601	transmembrane transport
VEA_002961	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VEA_002962	COG0444	Belongs to the ABC transporter superfamily
VEA_002964	COG0435	Glutathione S-transferase
VEA_002966	COG3174	membrane
VEA_002967	COG0857	belongs to the CobB CobQ family
VEA_002967	COG0280	phosphate acetyltransferase
VEA_002968	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VEA_002969	COG3092	negative regulation of chromosome organization
VEA_002971	COG4120	Belongs to the binding-protein-dependent transport system permease family
VEA_002972	COG1122	ATPase activity
VEA_002973	COG0366	Alpha amylase catalytic
VEA_002974	COG3706	GGDEF domain
VEA_002975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VEA_002976	COG0653	protein targeting
VEA_002977	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VEA_002978	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VEA_002979	COG2186	Transcriptional regulator
VEA_002981	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VEA_002981	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VEA_002983	COG0572	uridine kinase
VEA_002985	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VEA_002986	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VEA_002987	COG0659	secondary active sulfate transmembrane transporter activity
VEA_002988	COG1530	ribonuclease E activity
VEA_002989	COG0564	pseudouridine synthase activity
VEA_002990	COG0424	maF-like protein
VEA_002991	COG1399	metal-binding, possibly nucleic acid-binding protein
VEA_002993	COG0416	fatty acid biosynthetic process
VEA_002994	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VEA_003000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VEA_003001	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VEA_003002	COG0470	DNA polymerase III
VEA_003003	COG0084	hydrolase, TatD family'
VEA_003004	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VEA_003004	COG1263	PTS System
VEA_003007	COG0733	neurotransmitter:sodium symporter activity
VEA_003010	COG4667	esterase of the alpha-beta hydrolase superfamily
VEA_003011	COG0469	pyruvate kinase activity
VEA_003012	COG1940	carbohydrate kinase activity
VEA_003013	COG0784	Response regulator, receiver
VEA_003013	COG0835	chemotaxis
VEA_003014	COG0587	DNA-directed DNA polymerase activity
VEA_003017	COG1028	Short-chain dehydrogenase reductase Sdr
VEA_003018	COG0616	signal peptide processing
VEA_003019	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VEA_003020	COG0539	negative regulation of cytoplasmic translation
VEA_003022	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VEA_003023	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VEA_003025	COG4166	transmembrane transport
VEA_003028	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VEA_003028	COG3008	intermembrane lipid transfer
VEA_003029	COG2995	paraquat-inducible protein a
VEA_003030	COG3258	Cytochrome c
VEA_003031	COG2863	cytochrome
VEA_003038	COG4232	protein-disulfide reductase activity
VEA_003039	COG3118	belongs to the thioredoxin family
VEA_003046	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VEA_003049	COG1136	(ABC) transporter
VEA_003049	COG0577	efflux transmembrane transporter activity
VEA_003050	COG0577	efflux transmembrane transporter activity
VEA_003050	COG1136	(ABC) transporter
VEA_003054	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VEA_003061	COG5002	protein histidine kinase activity
VEA_003061	COG3850	Histidine kinase
VEA_003062	COG0745	RESPONSE REGULATOR receiver
VEA_003063	COG0840	transmembrane signaling receptor activity
VEA_003066	COG1032	radical SAM domain protein
VEA_003067	COG5001	Diguanylate cyclase
VEA_003070	COG0583	DNA-binding transcription factor activity
VEA_003071	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VEA_003073	COG2350	Protein conserved in bacteria
VEA_003074	COG1607	acyl-coa hydrolase
VEA_003075	COG2917	probably involved in intracellular septation
VEA_003079	COG1301	dicarboxylic acid transport
VEA_003081	COG0318	PFAM AMP-dependent synthetase and ligase
VEA_003082	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VEA_003083	COG0159	tryptophan synthase activity
VEA_003085	COG0135	phosphoribosylanthranilate isomerase activity
VEA_003085	COG0134	indole-3-glycerol-phosphate synthase activity
VEA_003087	COG0512	Glutamine amidotransferase of anthranilate synthase
VEA_003088	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VEA_003090	COG0613	PHP domain protein
VEA_003091	COG0009	L-threonylcarbamoyladenylate synthase
VEA_003093	COG1187	pseudouridine synthase activity
VEA_003097	COG0417	DNA replication proofreading
VEA_003098	COG2197	response regulator
VEA_003099	COG0322	excinuclease ABC activity
VEA_003103	COG0019	diaminopimelate decarboxylase activity
VEA_003108	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VEA_003109	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VEA_003110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VEA_003114	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
VEA_003116	COG0437	4 iron, 4 sulfur cluster binding
VEA_003117	COG3301	Polysulphide reductase, NrfD
VEA_003118	COG1138	Cytochrome C-type biogenesis protein
VEA_003120	COG4235	cytochrome complex assembly
VEA_003120	COG3088	subunit of a heme lyase
VEA_003122	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VEA_003127	COG2989	Protein conserved in bacteria
VEA_003128	COG3108	Peptidase M15
VEA_003129	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VEA_003132	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VEA_003138	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VEA_003139	COG0840	transmembrane signaling receptor activity
VEA_003143	COG1448	Aminotransferase
VEA_003147	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VEA_003150	COG0017	Asparaginyl-tRNA synthetase
VEA_003151	COG0840	transmembrane signaling receptor activity
VEA_003152	COG0720	synthase
VEA_003154	COG2200	EAL domain
VEA_003155	COG1760	l-serine dehydratase
VEA_003156	COG0814	amino acid
VEA_003157	COG0494	nUDIX hydrolase
VEA_003159	COG2205	protein histidine kinase activity
VEA_003159	COG0784	Response regulator, receiver
VEA_003160	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VEA_003163	COG3106	COG3106 Predicted ATPase
VEA_003164	COG3768	UPF0283 membrane protein
VEA_003166	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VEA_003217	COG4735	regulation of single-species biofilm formation
VEA_003219	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VEA_003219	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VEA_003234	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VEA_003242	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VEA_003253	COG0582	viral genome integration into host DNA
VEA_003284	COG0582	viral genome integration into host DNA
VEA_003289	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VEA_003290	COG0210	DNA helicase
VEA_003294	COG0456	acetyltransferase
VEA_003296	COG0625	glutathione transferase activity
VEA_003305	COG5507	3-demethylubiquinone-9 3-methyltransferase
VEA_003307	COG1280	lysine exporter protein (LysE YggA)
VEA_003312	COG0583	DNA-binding transcription factor activity
VEA_003314	COG1566	PFAM secretion protein HlyD family protein
VEA_003317	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VEA_003319	COG3290	protein histidine kinase activity
VEA_003320	COG4565	transcriptional regulatory protein
VEA_003322	COG4977	sequence-specific DNA binding
VEA_003323	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VEA_003324	COG0363	glucosamine-6-phosphate deaminase activity
VEA_003325	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VEA_003329	COG3284	Transcriptional regulator
VEA_003330	COG1012	belongs to the aldehyde dehydrogenase family
VEA_003344	COG4669	(LipO)protein
VEA_003348	COG3177	Filamentation induced by cAMP protein fic
VEA_003354	COG1028	Short-chain dehydrogenase reductase Sdr
VEA_003356	COG1566	PFAM secretion protein HlyD family protein
VEA_003359	COG4792	protein secretion
VEA_003360	COG4791	protein targeting
VEA_003361	COG4794	Type iii secretion
VEA_003362	COG4790	Type iii secretion
VEA_003363	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VEA_003376	COG0457	Tetratricopeptide repeat
VEA_003380	COG0730	response to heat
VEA_003388	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VEA_003389	COG0372	Belongs to the citrate synthase family
VEA_003391	COG2828	Protein conserved in bacteria
VEA_003397	COG0561	phosphatase activity
VEA_003398	COG0602	queuosine metabolic process
VEA_003399	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VEA_003400	COG3706	GGDEF domain
VEA_003410	COG1254	Belongs to the acylphosphatase family
VEA_003411	COG2920	part of a sulfur-relay system
VEA_003413	COG0670	Belongs to the BI1 family
VEA_003414	COG1126	abc transporter atp-binding protein
VEA_003415	COG0765	amino acid transport
VEA_003416	COG4597	amino acid ABC transporter
VEA_003418	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VEA_003420	COG1666	GTP binding
VEA_003421	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VEA_003426	COG3008	intermembrane lipid transfer
VEA_003427	COG2995	paraquat-inducible protein a
VEA_003428	COG1132	(ABC) transporter
VEA_003429	COG1956	GAF domain-containing protein
VEA_003430	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VEA_003433	COG0308	aminopeptidase N
VEA_003435	COG2902	Dehydrogenase
VEA_003436	COG0167	dihydroorotate dehydrogenase activity
VEA_003438	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VEA_003438	COG0116	Belongs to the methyltransferase superfamily
VEA_003443	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VEA_003444	COG1067	ATP-dependent peptidase activity
VEA_003445	COG3120	sequence-specific DNA binding
VEA_003467	COG3278	Belongs to the heme-copper respiratory oxidase family
VEA_003470	COG2010	Cytochrome c
VEA_003472	COG2217	Heavy metal translocating P-type atpase
VEA_003475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VEA_003476	COG0589	response to stress
VEA_003481	COG3842	ATPase activity
VEA_003482	COG1176	ABC-type spermidine putrescine transport system, permease component I
VEA_003483	COG1177	transmembrane transport
VEA_003484	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VEA_003485	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VEA_003486	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VEA_003488	COG0004	ammonium transporteR
VEA_003493	COG0437	4 iron, 4 sulfur cluster binding
VEA_003494	COG3383	formate dehydrogenase (NAD+) activity
VEA_003494	COG0243	molybdopterin cofactor binding
VEA_003496	COG3381	protein complex oligomerization
VEA_003500	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VEA_003501	COG0488	(ABC) transporter
VEA_003502	COG4191	Histidine kinase
VEA_003503	COG2204	response regulator
VEA_003506	COG3842	ATPase activity
VEA_003507	COG0746	molybdenum cofactor guanylyltransferase activity
VEA_003508	COG0303	'Molybdopterin
VEA_003510	COG1940	carbohydrate kinase activity
VEA_003516	COG0840	transmembrane signaling receptor activity
VEA_003517	COG0791	NLP P60 protein
VEA_003519	COG3706	GGDEF domain
VEA_003523	COG0307	riboflavin synthase, alpha
VEA_003524	COG0534	Mate efflux family protein
VEA_003526	COG1793	dna ligase
VEA_003533	COG2204	response regulator
VEA_003535	COG0438	transferase activity, transferring glycosyl groups
VEA_003541	COG0438	transferase activity, transferring glycosyl groups
VEA_003542	COG1215	transferase activity, transferring glycosyl groups
VEA_003543	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VEA_003545	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VEA_003548	COG1643	Atp-dependent helicase
VEA_003549	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
VEA_003558	COG0443	Heat shock 70 kDa protein
VEA_003559	COG0443	Heat shock 70 kDa protein
VEA_003563	COG4968	Prepilin-type N-terminal cleavage methylation domain
VEA_003564	COG1132	(ABC) transporter
VEA_003565	COG1132	(ABC) transporter
VEA_003567	COG4774	siderophore transport
VEA_003569	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VEA_003570	COG1120	ATPase activity
VEA_003573	COG0814	amino acid
VEA_003575	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VEA_003577	COG0861	Integral membrane protein TerC family
VEA_003579	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VEA_003580	COG1328	CTP reductase activity
VEA_003583	COG5001	Diguanylate cyclase
VEA_003583	COG3300	MHYT domain
VEA_003585	COG4191	Histidine kinase
VEA_003586	COG0471	metal ion transport
VEA_003591	COG3706	GGDEF domain
VEA_003591	COG0745	RESPONSE REGULATOR receiver
VEA_003593	COG4702	Belongs to the UPF0303 family
VEA_003594	COG0673	inositol 2-dehydrogenase activity
VEA_003595	COG1349	DNA-binding transcription factor activity
VEA_003598	COG0641	radical SAM
VEA_003601	COG3119	arylsulfatase activity
VEA_003602	COG0527	aspartate kinase activity
VEA_003603	COG0662	Cupin 2, conserved barrel domain protein
VEA_003604	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VEA_003605	COG0456	acetyltransferase
VEA_003606	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VEA_003610	COG4176	ABC-type proline glycine betaine transport system permease component
VEA_003611	COG2113	Glycine betaine
VEA_003613	COG1022	Amp-dependent synthetase and ligase
VEA_003615	COG1028	Short-chain dehydrogenase reductase Sdr
VEA_003617	COG0745	RESPONSE REGULATOR receiver
VEA_003618	COG0642	Histidine kinase
VEA_003619	COG1368	sulfuric ester hydrolase activity
VEA_003625	COG1115	amino acid carrier protein
VEA_003627	COG1280	lysine exporter protein (LysE YggA)
VEA_003628	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VEA_003629	COG1560	Kdo2-lipid A biosynthetic process
VEA_003630	COG0531	amino acid
VEA_003633	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VEA_003634	COG3063	Type IV pilus biogenesis stability protein PilW
VEA_003640	COG0110	maltose O-acetyltransferase activity
VEA_003643	COG2315	Protein conserved in bacteria
VEA_003644	COG1846	Transcriptional regulator
VEA_003646	COG2200	EAL domain
VEA_003652	COG0625	glutathione transferase activity
VEA_003654	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VEA_003656	COG2195	Cleaves the N-terminal amino acid of tripeptides
VEA_003658	COG0601	transmembrane transport
VEA_003659	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VEA_003663	COG3291	Pkd domain containing protein
VEA_003666	COG1177	transmembrane transport
VEA_003667	COG1176	ABC-type spermidine putrescine transport system, permease component I
VEA_003668	COG3842	ATPase activity
VEA_003669	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VEA_003670	COG2423	ornithine cyclodeaminase activity
VEA_003673	COG3938	Belongs to the proline racemase family
VEA_003679	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
VEA_003680	COG1451	nucleotide metabolic process
VEA_003682	COG0583	DNA-binding transcription factor activity
VEA_003686	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
VEA_003687	COG4139	cobalamin transport
VEA_003688	COG2988	succinylglutamate desuccinylase activity
VEA_003692	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VEA_003693	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VEA_003694	COG0702	epimerase
VEA_003696	COG2925	Exonuclease
VEA_003697	COG1380	Effector of murein hydrolase LrgA
VEA_003698	COG1346	cytolysis
VEA_003699	COG0295	cytidine deaminase activity
VEA_003700	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
VEA_003701	COG0500	methyltransferase
VEA_003703	COG0776	regulation of translation
VEA_003705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VEA_003705	COG0072	phenylalanine-tRNA ligase activity
VEA_003706	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VEA_003712	COG0393	Putative heavy-metal-binding
VEA_003714	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VEA_003716	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
VEA_003719	COG2188	Transcriptional regulator
VEA_003720	COG1228	amidohydrolase
VEA_003721	COG0010	Belongs to the arginase family
VEA_003722	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VEA_003723	COG2986	histidine ammonia-lyase
VEA_003726	COG0277	FAD linked oxidase domain protein
VEA_003726	COG0247	lactate metabolic process
VEA_003733	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VEA_003736	COG1643	Atp-dependent helicase
VEA_003737	COG0281	malic enzyme
VEA_003738	COG2949	membrane
VEA_003739	COG0471	metal ion transport
VEA_003740	COG3706	GGDEF domain
VEA_003740	COG0745	RESPONSE REGULATOR receiver
VEA_003744	COG0492	ferredoxin-NADP+ reductase activity
VEA_003745	COG4988	ABC transporter
VEA_003746	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VEA_003748	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VEA_003750	COG4191	Histidine kinase
VEA_003750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VEA_003753	COG3070	regulator of competence-specific genes
VEA_003756	COG2431	L-lysine efflux transmembrane transporter activity
VEA_003759	COG0076	glutamate decarboxylase activity
VEA_003760	COG1737	Transcriptional regulator
VEA_003762	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VEA_003763	COG3273	potassium ion transport
VEA_003763	COG2985	domain, Protein
VEA_003764	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VEA_003765	COG1960	acyl-CoA dehydrogenase activity
VEA_003767	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VEA_003772	COG0534	Mate efflux family protein
VEA_003773	COG0702	epimerase
VEA_003774	COG3005	denitrification pathway
VEA_003780	COG2814	Major facilitator Superfamily
VEA_003781	COG1187	pseudouridine synthase activity
VEA_003782	COG1061	Type III restriction enzyme res subunit
VEA_003784	COG0745	RESPONSE REGULATOR receiver
VEA_003785	COG2205	protein histidine kinase activity
VEA_003787	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VEA_003791	COG3313	Fe-S protein
VEA_003793	COG4134	Bacterial extracellular solute-binding protein
VEA_003794	COG4135	transport system, permease component
VEA_003795	COG4136	ATPase activity
VEA_003796	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VEA_003798	COG3604	Transcriptional regulator
VEA_003799	COG1151	hydroxylamine reductase activity
VEA_003800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VEA_003802	COG0564	pseudouridine synthase activity
VEA_003803	COG0733	neurotransmitter:sodium symporter activity
VEA_003805	COG0626	cystathionine gamma-synthase activity
VEA_003806	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VEA_003808	COG2818	Glycosylase
VEA_003812	COG1983	PspC domain protein
VEA_003814	COG1842	Phage shock protein A
VEA_003815	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VEA_003817	COG4168	peptide transport system, permease
VEA_003818	COG4171	peptide transport system, permease
VEA_003820	COG4172	Belongs to the ABC transporter superfamily
VEA_003822	COG1227	inorganic diphosphatase activity
VEA_003825	COG0243	molybdopterin cofactor binding
VEA_003826	COG3005	denitrification pathway
VEA_003827	COG4459	periplasmic nitrate reductase
VEA_003828	COG0390	transport system, permease component
VEA_003830	COG2116	formate transmembrane transporter activity
VEA_003835	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VEA_003836	COG1435	thymidine kinase activity
VEA_003837	COG0215	cysteine-tRNA ligase activity
VEA_003838	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VEA_003839	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VEA_003840	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VEA_003841	COG3012	SEC-C Motif Domain Protein
VEA_003842	COG0140	phosphoribosyl-ATP diphosphatase activity
VEA_003842	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VEA_003843	COG0107	imidazoleglycerol-phosphate synthase activity
VEA_003844	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VEA_003845	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VEA_003846	COG0131	Imidazoleglycerol-phosphate dehydratase
VEA_003846	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VEA_003847	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VEA_003848	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VEA_003849	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VEA_003851	COG1757	Na H antiporter
VEA_003853	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VEA_003855	COG0482	sulfurtransferase activity
VEA_003856	COG2915	High frequency lysogenization protein hflD homolog
VEA_003857	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VEA_003859	COG2268	Band 7 protein
VEA_003861	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VEA_003864	COG0300	oxidoreductase activity
VEA_003868	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VEA_003869	COG1073	alpha beta
VEA_003869	COG2226	methyltransferase
VEA_003876	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VEA_003877	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VEA_003878	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VEA_003879	COG1674	ftsk spoiiie
VEA_003881	COG0686	Belongs to the AlaDH PNT family
VEA_003883	COG0583	DNA-binding transcription factor activity
VEA_003886	COG0840	transmembrane signaling receptor activity
VEA_003888	COG3568	Endonuclease Exonuclease Phosphatase
VEA_003894	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VEA_003895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VEA_003896	COG0840	transmembrane signaling receptor activity
VEA_003899	COG0328	RNA-DNA hybrid ribonuclease activity
VEA_003904	COG5002	protein histidine kinase activity
VEA_003904	COG0784	Response regulator, receiver
VEA_003906	COG0754	glutathionylspermidine amidase activity
VEA_003908	COG3766	membrane
VEA_003910	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VEA_003911	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
VEA_003912	COG2885	chlorophyll binding
VEA_003913	COG0823	Involved in the tonB-independent uptake of proteins
VEA_003916	COG0811	peptide transport
VEA_003917	COG0824	Thioesterase
VEA_003919	COG4890	Cyd operon protein YbgT
VEA_003920	COG1294	oxidase, subunit
VEA_003921	COG1271	oxidase subunit
VEA_003922	COG2255	four-way junction helicase activity
VEA_003923	COG0632	four-way junction helicase activity
VEA_003924	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VEA_003925	COG0217	transcriptional regulatory protein
VEA_003927	COG1801	Protein of unknown function DUF72
VEA_003929	COG0500	methyltransferase
VEA_003930	COG0189	ligase activity
VEA_003930	COG4067	protein conserved in archaea
VEA_003934	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
VEA_003935	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VEA_003936	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VEA_003937	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VEA_003938	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VEA_003939	COG0745	RESPONSE REGULATOR receiver
VEA_003940	COG3381	protein complex oligomerization
VEA_003941	COG1609	Transcriptional regulator
VEA_003942	COG3070	regulator of competence-specific genes
VEA_003946	COG0297	glycogen (starch) synthase activity
VEA_003947	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VEA_003948	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VEA_003953	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VEA_003954	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
VEA_003955	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VEA_003956	COG0542	response to heat
VEA_003957	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VEA_003958	COG1278	Cold shock
VEA_003960	COG1187	pseudouridine synthase activity
VEA_003961	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VEA_003962	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VEA_003963	COG1199	ATP-dependent helicase activity
VEA_003964	COG0730	response to heat
VEA_003965	COG3923	Primosomal replication protein n
VEA_003967	COG0708	Exodeoxyribonuclease III
VEA_003971	COG4215	(ABC) transporter
VEA_003976	COG1882	Formate acetyltransferase
VEA_003978	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VEA_003980	COG3013	Belongs to the UPF0304 family
VEA_003981	COG2766	serine protein kinase
VEA_003982	COG2718	Belongs to the UPF0229 family
VEA_003983	COG2719	SpoVR family
VEA_003987	COG1132	(ABC) transporter
VEA_003988	COG0658	competence protein
VEA_003988	COG2333	competence protein COMEC
VEA_003990	COG4591	ABC-type transport system involved in lipoprotein release permease component
VEA_003991	COG1136	(ABC) transporter
VEA_003992	COG4591	ABC-type transport system involved in lipoprotein release permease component
VEA_003994	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VEA_003997	COG1252	NADH dehydrogenase
VEA_003998	COG3150	esterase
VEA_004003	COG0537	adenosine 5'-monophosphoramidase activity
VEA_004008	COG0517	IMP dehydrogenase activity
VEA_004008	COG0516	GMP reductase activity
VEA_004009	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VEA_004010	COG0745	RESPONSE REGULATOR receiver
VEA_004010	COG3706	GGDEF domain
VEA_004013	COG3126	Type III secretion system lipoprotein chaperone (YscW)
VEA_004014	COG1946	Acyl-CoA thioesterase
VEA_004016	COG1522	sequence-specific DNA binding
VEA_004021	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VEA_004022	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VEA_004025	COG0477	Major facilitator Superfamily
VEA_004026	COG2855	membrane
VEA_004029	COG1441	menaquinone biosynthetic process
VEA_004030	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
VEA_004031	COG0596	Alpha beta hydrolase
VEA_004032	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VEA_004033	COG1169	isochorismate synthase
VEA_004034	COG0436	Aminotransferase
VEA_004035	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VEA_004036	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VEA_004039	COG1555	photosystem II stabilization
VEA_004040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VEA_004041	COG0776	regulation of translation
VEA_004042	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VEA_004043	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VEA_004045	COG0544	peptidyl-prolyl cis-trans isomerase activity
VEA_004048	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VEA_004049	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VEA_004050	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VEA_004051	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VEA_004054	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VEA_004055	COG0569	domain protein
VEA_004056	COG0513	Belongs to the DEAD box helicase family
VEA_004057	COG1253	flavin adenine dinucleotide binding
VEA_004064	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VEA_004065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VEA_004068	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VEA_004069	COG1216	Glycosyl transferase, family 2
VEA_004070	COG2986	histidine ammonia-lyase
VEA_004075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VEA_004076	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VEA_004077	COG1028	Short-chain dehydrogenase reductase Sdr
VEA_004078	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VEA_004081	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VEA_004082	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VEA_004084	COG2951	lytic endotransglycosylase activity
VEA_004085	COG3100	YcgL domain-containing protein
VEA_004086	COG0850	regulation of cytokinetic process
VEA_004087	COG2894	cell division
VEA_004088	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VEA_004089	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VEA_004090	COG0318	PFAM AMP-dependent synthetase and ligase
VEA_004091	COG2267	carboxylic ester hydrolase activity
VEA_004092	COG3065	identical protein binding
VEA_004094	COG1214	PFAM Peptidase M22, glycoprotease
VEA_004095	COG1199	ATP-dependent helicase activity
VEA_004096	COG0788	formyltetrahydrofolate deformylase activity
VEA_004099	COG3102	Protein conserved in bacteria
VEA_004100	COG0018	arginyl-trna synthetase
VEA_004104	COG1918	ferrous iron import across plasma membrane
VEA_004105	COG4977	sequence-specific DNA binding
VEA_004106	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VEA_004107	COG1121	(ABC) transporter
VEA_004108	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VEA_004111	COG0508	dehydrogenase complex catalyzes the overall conversion of
VEA_004112	COG0567	Dehydrogenase, E1 component
VEA_004113	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VEA_004114	COG1053	succinate dehydrogenase
VEA_004115	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VEA_004116	COG2009	succinate dehydrogenase
VEA_004118	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VEA_004120	COG0033	Phosphoglucomutase
VEA_004121	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VEA_004122	COG0596	Alpha beta hydrolase
VEA_004124	COG0716	FMN binding
VEA_004126	COG0735	belongs to the Fur family
VEA_004127	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VEA_004128	COG1263	PTS System
VEA_004128	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VEA_004129	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VEA_004130	COG1846	Transcriptional regulator
VEA_004130	COG1940	carbohydrate kinase activity
VEA_004131	COG4651	solute:proton antiporter activity
VEA_004131	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VEA_004132	COG0367	asparagine synthase
VEA_004133	COG0250	Participates in transcription elongation, termination and antitermination
VEA_004134	COG3104	oligopeptide transport
VEA_004135	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VEA_004137	COG0326	Molecular chaperone. Has ATPase activity
VEA_004138	COG3710	Transcriptional regulator
VEA_004142	COG0622	Phosphoesterase
VEA_004147	COG1090	epimerase
VEA_004148	COG0300	oxidoreductase activity
VEA_004149	COG3118	belongs to the thioredoxin family
VEA_004150	COG0330	HflC and HflK could
VEA_004153	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VEA_004154	COG3115	cell septum assembly
VEA_004155	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VEA_004156	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VEA_004157	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VEA_004158	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
VEA_004159	COG2190	(PTS) system
VEA_004160	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VEA_004161	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VEA_004162	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VEA_004163	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VEA_004165	COG1705	Flagellar rod assembly protein muramidase FlgJ
VEA_004165	COG3951	Flagellar rod assembly protein muramidase FlgJ
VEA_004166	COG1706	bacterial-type flagellum-dependent cell motility
VEA_004167	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VEA_004168	COG4786	Flagellar basal body rod
VEA_004169	COG4787	bacterial-type flagellum-dependent cell motility
VEA_004170	COG1749	Flagellar hook protein flgE
VEA_004171	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
VEA_004172	COG1558	bacterial-type flagellum-dependent cell motility
VEA_004173	COG1815	bacterial-type flagellum-dependent cell motility
VEA_004174	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VEA_004175	COG0835	chemotaxis
VEA_004175	COG0784	Response regulator, receiver
VEA_004185	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VEA_004188	COG2217	Heavy metal translocating P-type atpase
VEA_004188	COG2608	mercury ion transmembrane transporter activity
VEA_004195	COG2840	Smr protein MutS2
VEA_004196	COG1187	pseudouridine synthase activity
VEA_004198	COG0737	Belongs to the 5'-nucleotidase family
VEA_004199	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VEA_004200	COG2912	Transglutaminase-like superfamily
VEA_004201	COG3094	Invasion gene expression up-regulator, SirB
VEA_004202	COG2890	protein-(glutamine-N5) methyltransferase activity
VEA_004203	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VEA_004204	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VEA_004205	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VEA_004207	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VEA_004208	COG0193	aminoacyl-tRNA hydrolase activity
VEA_004209	COG0012	GTP binding
VEA_004210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VEA_004211	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VEA_004212	COG1702	phosphate starvation-inducible protein PhoH
VEA_004213	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VEA_004214	COG4535	Mg2 and Co2 transporter CorC
VEA_004215	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VEA_004216	COG2888	peptidyl-tyrosine sulfation
VEA_004217	COG0495	leucyl-tRNA aminoacylation
VEA_004218	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VEA_004219	COG1466	dna polymerase III delta subunit
VEA_004220	COG0799	negative regulation of ribosome biogenesis
VEA_004221	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VEA_004222	COG0768	penicillin binding
VEA_004223	COG0772	Belongs to the SEDS family
VEA_004224	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VEA_004225	COG1686	Belongs to the peptidase S11 family
VEA_004227	COG0321	lipoyl(octanoyl) transferase activity
VEA_004228	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VEA_004230	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VEA_004231	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
VEA_004234	COG0366	Alpha amylase catalytic
VEA_004235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VEA_004235	COG1263	PTS System
VEA_004237	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VEA_004238	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VEA_004239	COG2011	ABC-type metal ion transport system permease component
VEA_004240	COG1464	Belongs to the NlpA lipoprotein family
VEA_004241	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VEA_004244	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VEA_004244	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VEA_004246	COG0745	RESPONSE REGULATOR receiver
VEA_004246	COG3706	GGDEF domain
VEA_004247	COG1611	Belongs to the LOG family
VEA_004248	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VEA_004250	COG2363	Small membrane protein
VEA_004252	COG0583	DNA-binding transcription factor activity
VEA_004253	COG0301	tRNA thio-modification
VEA_004253	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VEA_004255	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VEA_004256	COG1722	exodeoxyribonuclease VII activity
VEA_004257	COG0142	geranyltranstransferase activity
VEA_004258	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VEA_004259	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VEA_004260	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VEA_004265	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VEA_004265	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VEA_004266	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VEA_004267	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VEA_004268	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VEA_004271	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VEA_004272	COG2252	PERMEase
VEA_004273	COG2195	Cleaves the N-terminal amino acid of tripeptides
VEA_004277	COG1629	transport
VEA_004280	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VEA_004280	COG0047	phosphoribosylformylglycinamidine synthase activity
VEA_004281	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VEA_004282	COG0590	tRNA wobble adenosine to inosine editing
VEA_004283	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VEA_004289	COG0484	heat shock protein binding
VEA_004292	COG1301	dicarboxylic acid transport
VEA_004293	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VEA_004294	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VEA_004296	COG0497	DNA recombination
VEA_004297	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VEA_004298	COG2914	Belongs to the UPF0125 (RnfH) family
VEA_004299	COG2867	negative regulation of translational initiation
VEA_004300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VEA_004301	COG0582	viral genome integration into host DNA
VEA_004310	COG3311	Transcriptional regulator
VEA_004316	COG0583	DNA-binding transcription factor activity
VEA_004318	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VEA_004318	COG3153	acetyltransferase
VEA_004322	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VEA_004323	COG2873	o-acetylhomoserine
VEA_004327	COG1115	amino acid carrier protein
VEA_004328	COG1584	GPR1 FUN34 yaaH family protein
VEA_004330	COG1757	Na H antiporter
VEA_004339	COG0582	viral genome integration into host DNA
VEA_004340	COG0519	Catalyzes the synthesis of GMP from XMP
VEA_004340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VEA_004341	COG0517	IMP dehydrogenase activity
VEA_004341	COG0516	GMP reductase activity
VEA_004345	COG1160	GTP binding
VEA_004346	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VEA_004347	COG2976	Protein conserved in bacteria
VEA_004348	COG0124	histidyl-tRNA synthetase
VEA_004349	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VEA_004352	COG0105	UTP biosynthetic process
VEA_004354	COG2975	iron-sulfur cluster assembly
VEA_004355	COG0633	Ferredoxin
VEA_004356	COG0443	Heat shock 70 kDa protein
VEA_004359	COG0822	iron-sulfur transferase activity
VEA_004360	COG1104	cysteine desulfurase activity
VEA_004362	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
VEA_004363	COG0483	inositol monophosphate 1-phosphatase activity
VEA_004364	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VEA_004365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VEA_004366	COG1862	Preprotein translocase
VEA_004368	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
VEA_004370	COG0517	IMP dehydrogenase activity
VEA_004372	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VEA_004373	COG0583	DNA-binding transcription factor activity
VEA_004374	COG0450	alkyl hydroperoxide reductase
VEA_004375	COG3142	Participates in the control of copper homeostasis
VEA_004377	COG0704	Plays a role in the regulation of phosphate uptake
VEA_004378	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VEA_004379	COG0581	inorganic phosphate transmembrane transporter activity
VEA_004380	COG0573	inorganic phosphate transmembrane transporter activity
VEA_004381	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VEA_004382	COG0248	Ppx GppA phosphatase
VEA_004384	COG5002	protein histidine kinase activity
VEA_004385	COG0745	RESPONSE REGULATOR receiver
VEA_004386	COG2974	May be involved in recombination
VEA_004388	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VEA_004392	COG0542	response to heat
VEA_004394	COG0564	pseudouridine synthase activity
VEA_004395	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VEA_004396	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VEA_004397	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VEA_004398	COG0077	Prephenate dehydratase
VEA_004398	COG1605	Chorismate mutase
VEA_004399	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
VEA_004400	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VEA_004402	COG0488	(ABC) transporter
VEA_004404	COG0741	lytic transglycosylase activity
VEA_004404	COG0739	heme binding
VEA_004404	COG1196	nuclear chromosome segregation
VEA_004405	COG0287	Prephenate dehydrogenase
VEA_004405	COG1605	Chorismate mutase
VEA_004406	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VEA_004407	COG1472	Belongs to the glycosyl hydrolase 3 family
VEA_004408	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VEA_004412	COG1966	Carbon starvation protein
VEA_004413	COG3275	phosphorelay sensor kinase activity
VEA_004414	COG3279	Response regulator of the LytR AlgR family
VEA_004416	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VEA_004417	COG1047	Peptidyl-prolyl cis-trans
VEA_004418	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VEA_004420	COG0196	riboflavin kinase activity
VEA_004421	COG0728	peptidoglycan biosynthetic process
VEA_004422	COG0268	Binds directly to 16S ribosomal RNA
VEA_004423	COG0640	Transcriptional regulator
VEA_004424	COG0583	DNA-binding transcription factor activity
VEA_004425	COG1283	sodium-dependent phosphate transmembrane transporter activity
VEA_004427	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
VEA_004429	COG0730	response to heat
VEA_004434	COG0667	Aldo Keto reductase
VEA_004436	COG2204	response regulator
VEA_004437	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VEA_004438	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VEA_004439	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VEA_004440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VEA_004442	COG0716	FMN binding
VEA_004444	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
VEA_004445	COG0513	Belongs to the DEAD box helicase family
VEA_004446	COG3022	response to hydroperoxide
VEA_004447	COG1115	amino acid carrier protein
VEA_004450	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VEA_004452	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VEA_004453	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VEA_004455	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VEA_004456	COG0083	homoserine kinase activity
VEA_004459	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VEA_004461	COG0745	RESPONSE REGULATOR receiver
VEA_004463	COG5002	protein histidine kinase activity
VEA_004463	COG0784	Response regulator, receiver
VEA_004463	COG2198	Histidine kinase
VEA_004464	COG4251	negative regulation of phosphorylation
VEA_004464	COG3706	GGDEF domain
VEA_004464	COG2203	Gaf domain
VEA_004464	COG5001	Diguanylate cyclase
VEA_004465	COG1242	4 iron, 4 sulfur cluster binding
VEA_004466	COG0069	glutamate synthase activity
VEA_004466	COG0067	glutamate synthase
VEA_004466	COG0070	glutamate synthase
VEA_004468	COG0070	glutamate synthase
VEA_004468	COG0067	glutamate synthase
VEA_004468	COG0069	glutamate synthase activity
VEA_004469	COG0493	'glutamate synthase
VEA_004471	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VEA_004474	COG2860	membrane
VEA_004476	COG0730	response to heat
VEA_004478	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VEA_004479	COG0505	Belongs to the CarA family
VEA_004482	COG0494	nUDIX hydrolase
VEA_004483	COG0653	protein targeting
VEA_004485	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VEA_004486	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VEA_004487	COG0849	cell division
VEA_004488	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VEA_004489	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VEA_004491	COG0772	Belongs to the SEDS family
VEA_004492	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VEA_004493	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VEA_004494	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VEA_004495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VEA_004496	COG0768	penicillin binding
VEA_004497	COG3116	cell division
VEA_004500	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VEA_004503	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VEA_004504	COG2823	Periplasmic or secreted lipoprotein
VEA_004505	COG2969	positive regulation of protein catabolic process
VEA_004506	COG0625	glutathione transferase activity
VEA_004507	COG2857	Cytochrome c1
VEA_004508	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VEA_004509	COG0723	plastoquinol--plastocyanin reductase activity
VEA_004510	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VEA_004511	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VEA_004512	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VEA_004513	COG3105	Protein conserved in bacteria
VEA_004515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VEA_004516	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VEA_004517	COG0187	DNA topoisomerase II activity
VEA_004518	COG3150	esterase
VEA_004520	COG3151	Protein conserved in bacteria
VEA_004521	COG0494	nUDIX hydrolase
VEA_004522	COG1538	Outer membrane efflux protein
VEA_004523	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
VEA_004523	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
VEA_004524	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VEA_004527	COG3025	triphosphatase activity
VEA_004528	COG1392	Phosphate transport regulator
VEA_004529	COG0306	phosphate transporter