locus-tag	class	description
GT360_00025	COG1126	abc transporter atp-binding protein
GT360_00055	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GT360_00070	COG1192	Involved in chromosome partitioning
GT360_00075	COG1475	DNA binding
GT360_00095	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GT360_00100	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GT360_00105	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GT360_00110	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GT360_00120	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GT360_00130	COG0765	amino acid transport
GT360_00135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT360_00140	COG0183	Belongs to the thiolase family
GT360_00150	COG1739	Uncharacterized protein family UPF0029
GT360_00155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GT360_00210	COG3977	Valine--pyruvate aminotransferase
GT360_00215	COG0366	Alpha amylase catalytic
GT360_00220	COG0751	glycine-tRNA ligase activity
GT360_00230	COG2119	membrane
GT360_00240	COG0425	Belongs to the sulfur carrier protein TusA family
GT360_00255	COG0604	alcohol dehydrogenase
GT360_00265	COG0129	dihydroxy-acid dehydratase activity
GT360_00270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GT360_00275	COG3978	acetolactate synthase activity
GT360_00285	COG0606	chelatase, subunit chli
GT360_00300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GT360_00340	COG0204	Acyl-transferase
GT360_00345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GT360_00350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GT360_00360	COG3084	Protein conserved in bacteria
GT360_00365	COG4326	sporulation control protein
GT360_00370	COG1272	protein, Hemolysin III
GT360_00380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GT360_00385	COG0569	domain protein
GT360_00390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GT360_00390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GT360_00400	COG0242	peptide deformylase activity
GT360_00405	COG1652	LysM domain
GT360_00410	COG0758	DNA mediated transformation
GT360_00420	COG0551	DNA topoisomerase type I activity
GT360_00425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GT360_00430	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GT360_00445	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GT360_00455	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GT360_00495	COG0459	protein refolding
GT360_00500	COG0515	serine threonine protein kinase
GT360_00505	COG1494	fructose-1,6-bisphosphatase
GT360_00515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GT360_00520	COG0460	homoserine dehydrogenase
GT360_00520	COG0527	aspartate kinase activity
GT360_00525	COG0626	cystathionine gamma-synthase activity
GT360_00535	COG1609	Transcriptional regulator
GT360_00540	COG0129	dihydroxy-acid dehydratase activity
GT360_00545	COG3265	gluconokinase activity
GT360_00550	COG2610	gluconate transmembrane transporter activity
GT360_00555	COG0800	Aldolase
GT360_00565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GT360_00570	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GT360_00575	COG0339	signal peptide processing
GT360_00590	COG3220	belongs to the UPF0276 family
GT360_00600	COG0210	DNA helicase
GT360_00610	COG1280	lysine exporter protein (LysE YggA)
GT360_00615	COG2962	Rard protein
GT360_00620	COG0514	ATP-dependent DNA helicase (RecQ)
GT360_00630	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GT360_00635	COG0248	Ppx GppA phosphatase
GT360_00645	COG3118	belongs to the thioredoxin family
GT360_00660	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GT360_00720	COG3071	HemY protein
GT360_00725	COG2959	enzyme of heme biosynthesis
GT360_00730	COG1587	Uroporphyrinogen-III synthase
GT360_00740	COG3072	Adenylate cyclase
GT360_00745	COG1965	Belongs to the frataxin family
GT360_00755	COG0019	diaminopimelate decarboxylase activity
GT360_00770	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GT360_00775	COG1011	Hydrolase
GT360_00795	COG0561	phosphatase activity
GT360_00800	COG2267	carboxylic ester hydrolase activity
GT360_00805	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GT360_00810	COG0640	Transcriptional regulator
GT360_00815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GT360_00865	COG2095	MarC family integral membrane protein
GT360_00875	COG0742	ribosomal rna small subunit methyltransferase
GT360_00880	COG0552	protein localization to endoplasmic reticulum
GT360_00885	COG2884	Cell division ATP-binding protein ftsE
GT360_00890	COG2177	Part of the ABC transporter FtsEX involved in
GT360_00910	COG1580	Controls the rotational direction of flagella during chemotaxis
GT360_00915	COG3161	chorismate lyase activity
GT360_00920	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GT360_00925	COG2937	Belongs to the GPAT DAPAT family
GT360_00930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GT360_00935	COG0534	Mate efflux family protein
GT360_00940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GT360_00955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GT360_00960	COG4206	TonB-dependent receptor
GT360_01075	COG1561	YicC-like family, N-terminal region
GT360_01080	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GT360_01085	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GT360_01090	COG1560	Kdo2-lipid A biosynthetic process
GT360_01095	COG1309	transcriptional regulator
GT360_01100	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GT360_01110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GT360_01115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GT360_01120	COG1758	RNA polymerase activity
GT360_01125	COG0194	GDP metabolic process
GT360_01130	COG2252	PERMEase
GT360_01135	COG1609	Transcriptional regulator
GT360_01145	COG2017	converts alpha-aldose to the beta-anomer
GT360_01150	COG3459	Glycosyltransferase 36 associated
GT360_01155	COG3842	ATPase activity
GT360_01160	COG2723	6-phospho-beta-galactosidase activity
GT360_01165	COG0395	ABC-type sugar transport system, permease component
GT360_01170	COG1175	transmembrane transport
GT360_01180	COG1609	Transcriptional regulator
GT360_01195	COG1573	uracil-dna glycosylase
GT360_01200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT360_01205	COG3068	Protein conserved in bacteria
GT360_01210	COG1253	flavin adenine dinucleotide binding
GT360_01225	COG0151	Belongs to the GarS family
GT360_01235	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GT360_01250	COG0439	Biotin carboxylase
GT360_01255	COG0511	ligase activity, forming carbon-carbon bonds
GT360_01260	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GT360_01270	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GT360_01275	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GT360_01275	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GT360_01280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GT360_01285	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GT360_01295	COG1045	serine acetyltransferase
GT360_01305	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GT360_01315	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GT360_01320	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GT360_01325	COG0137	argininosuccinate synthase activity
GT360_01330	COG0165	Argininosuccinate lyase
GT360_01330	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GT360_01340	COG0678	peroxiredoxin activity
GT360_01340	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GT360_01350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GT360_01365	COG2814	Major facilitator Superfamily
GT360_01370	COG0784	Response regulator, receiver
GT360_01370	COG2205	protein histidine kinase activity
GT360_01370	COG2198	Histidine kinase
GT360_01380	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT360_01390	COG3263	regulation of cellular component size
GT360_01405	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GT360_01410	COG1027	Aspartate ammonia-lyase
GT360_01420	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GT360_01425	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GT360_01440	COG1061	Type III restriction enzyme res subunit
GT360_01485	COG2205	protein histidine kinase activity
GT360_01490	COG0745	RESPONSE REGULATOR receiver
GT360_01520	COG0512	Glutamine amidotransferase of anthranilate synthase
GT360_01525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GT360_01545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GT360_01550	COG3954	Phosphoribulokinase
GT360_01560	COG0429	hydrolase of the alpha beta-hydrolase fold
GT360_01570	COG0488	(ABC) transporter
GT360_01590	COG1047	Peptidyl-prolyl cis-trans
GT360_01600	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GT360_01605	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GT360_01615	COG1959	2 iron, 2 sulfur cluster binding
GT360_01620	COG0557	exoribonuclease II activity
GT360_01625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GT360_01630	COG0051	transcription antitermination factor activity, RNA binding
GT360_01640	COG0088	Forms part of the polypeptide exit tunnel
GT360_01660	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GT360_01670	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GT360_01680	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GT360_01690	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GT360_01695	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GT360_01710	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GT360_01725	COG1841	ribosomal large subunit assembly
GT360_01735	COG0201	protein transport
GT360_01740	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GT360_01745	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GT360_01750	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GT360_01765	COG0203	ribosomal protein L17
GT360_01775	COG0545	Peptidyl-prolyl cis-trans isomerase
GT360_01785	COG2153	protein acetylation
GT360_01790	COG0737	Belongs to the 5'-nucleotidase family
GT360_01795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GT360_01795	COG1648	precorrin-2 dehydrogenase activity
GT360_01800	COG0175	sulfate reduction
GT360_01810	COG0471	metal ion transport
GT360_01810	COG3273	potassium ion transport
GT360_01815	COG0529	Catalyzes the synthesis of activated sulfate
GT360_01850	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GT360_01860	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GT360_01865	COG0729	surface antigen
GT360_01875	COG2105	PFAM AIG2 family protein
GT360_01885	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GT360_01895	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GT360_01900	COG0163	prenyltransferase activity
GT360_01905	COG3028	Belongs to the UPF0307 family
GT360_01910	COG0312	modulator of DNA gyrase
GT360_01915	COG2239	Acts as a magnesium transporter
GT360_01920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT360_01925	COG1660	Displays ATPase and GTPase activities
GT360_01930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT360_01935	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GT360_01945	COG1137	ATPase activity
GT360_01950	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GT360_01960	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GT360_01975	COG1127	ABC transporter
GT360_01980	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GT360_01985	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GT360_01990	COG2854	intermembrane phospholipid transfer
GT360_01995	COG3113	response to antibiotic
GT360_02000	COG5007	Belongs to the BolA IbaG family
GT360_02010	COG0204	Acyl-transferase
GT360_02040	COG0840	transmembrane signaling receptor activity
GT360_02085	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GT360_02090	COG1194	a g-specific adenine glycosylase
GT360_02105	COG2066	Belongs to the glutaminase family
GT360_02110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GT360_02115	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GT360_02130	COG0762	integral membrane protein
GT360_02135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GT360_02140	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GT360_02155	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GT360_02160	COG1678	Uncharacterized ACR, COG1678
GT360_02165	COG0189	ligase activity
GT360_02170	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GT360_02175	COG3091	SprT-like family
GT360_02185	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GT360_02190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GT360_02205	COG0589	response to stress
GT360_02215	COG2358	TRAP transporter, solute receptor (TAXI family
GT360_02235	COG0142	geranyltranstransferase activity
GT360_02240	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GT360_02250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GT360_02255	COG2966	Psort location CytoplasmicMembrane, score
GT360_02260	COG3610	response to peptide
GT360_02285	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GT360_02290	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GT360_02295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GT360_02300	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GT360_02305	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GT360_02310	COG0251	oxidation-reduction process
GT360_02315	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GT360_02320	COG0540	Belongs to the ATCase OTCase family
GT360_02335	COG0583	DNA-binding transcription factor activity
GT360_02340	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GT360_02345	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GT360_02360	COG0564	pseudouridine synthase activity
GT360_02365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT360_02430	COG0473	3-isopropylmalate dehydrogenase activity
GT360_02435	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GT360_02465	COG0583	DNA-binding transcription factor activity
GT360_02470	COG1022	Amp-dependent synthetase and ligase
GT360_02475	COG0028	Belongs to the TPP enzyme family
GT360_02480	COG0440	acetolactate synthase activity
GT360_02485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT360_02490	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GT360_02495	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GT360_02510	COG3079	Belongs to the UPF0149 family
GT360_02515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GT360_02520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GT360_02535	COG0354	folic acid binding
GT360_02540	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GT360_02550	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GT360_02555	COG1595	DNA-templated transcription, initiation
GT360_02575	COG0481	GTPase activity
GT360_02585	COG0571	ribonuclease III activity
GT360_02590	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GT360_02595	COG1381	Involved in DNA repair and RecF pathway recombination
GT360_02600	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GT360_02605	COG0736	holo-[acyl-carrier-protein] synthase activity
GT360_02610	COG3850	Histidine kinase
GT360_02610	COG2205	protein histidine kinase activity
GT360_02610	COG3437	response regulator, receiver
GT360_02610	COG4999	Histidine kinase
GT360_02615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GT360_02620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GT360_02625	COG3956	TIGRFAM MazG family protein
GT360_02635	COG0148	phosphopyruvate hydratase activity
GT360_02650	COG3267	Type II secretory pathway component ExeA
GT360_02650	COG3409	Peptidoglycan-binding domain 1 protein
GT360_02660	COG4991	sh3 domain protein
GT360_02665	COG0306	phosphate transporter
GT360_02670	COG1392	Phosphate transport regulator
GT360_02675	COG3025	triphosphatase activity
GT360_02685	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GT360_02695	COG1538	Outer membrane efflux protein
GT360_02700	COG0494	nUDIX hydrolase
GT360_02705	COG3151	Protein conserved in bacteria
GT360_02715	COG3150	esterase
GT360_02720	COG0187	DNA topoisomerase II activity
GT360_02730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GT360_02735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GT360_02745	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GT360_02750	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GT360_02760	COG0723	plastoquinol--plastocyanin reductase activity
GT360_02765	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GT360_02770	COG2857	Cytochrome c1
GT360_02775	COG0625	glutathione transferase activity
GT360_02780	COG2969	positive regulation of protein catabolic process
GT360_02785	COG2823	Periplasmic or secreted lipoprotein
GT360_02790	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GT360_02795	COG0792	nuclease activity
GT360_02800	COG3107	peptidoglycan biosynthetic process
GT360_02805	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GT360_02820	COG3116	cell division
GT360_02825	COG0768	penicillin binding
GT360_02830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GT360_02835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GT360_02845	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GT360_02850	COG0772	Belongs to the SEDS family
GT360_02860	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GT360_02865	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GT360_02870	COG0849	cell division
GT360_02875	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GT360_02880	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GT360_02895	COG0494	nUDIX hydrolase
GT360_02905	COG0505	Belongs to the CarA family
GT360_02910	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GT360_02915	COG2130	NADP-dependent
GT360_02925	COG1283	sodium-dependent phosphate transmembrane transporter activity
GT360_02930	COG1283	sodium-dependent phosphate transmembrane transporter activity
GT360_02935	COG0583	DNA-binding transcription factor activity
GT360_02940	COG0640	Transcriptional regulator
GT360_02945	COG0268	Binds directly to 16S ribosomal RNA
GT360_02950	COG0728	peptidoglycan biosynthetic process
GT360_02955	COG0196	riboflavin kinase activity
GT360_02970	COG1047	Peptidyl-prolyl cis-trans
GT360_02975	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GT360_02985	COG1966	Carbon starvation protein
GT360_02995	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GT360_03000	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GT360_03010	COG3279	Response regulator of the LytR AlgR family
GT360_03015	COG3275	phosphorelay sensor kinase activity
GT360_03020	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GT360_03025	COG1605	Chorismate mutase
GT360_03025	COG0287	Prephenate dehydrogenase
GT360_03030	COG0739	heme binding
GT360_03035	COG0488	(ABC) transporter
GT360_03040	COG0741	lytic transglycosylase activity
GT360_03045	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GT360_03050	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GT360_03055	COG5001	Diguanylate cyclase
GT360_03060	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GT360_03065	COG0077	Prephenate dehydratase
GT360_03065	COG1605	Chorismate mutase
GT360_03070	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GT360_03075	COG0741	lytic transglycosylase activity
GT360_03080	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GT360_03085	COG0564	pseudouridine synthase activity
GT360_03095	COG0542	response to heat
GT360_03135	COG0483	inositol monophosphate 1-phosphatase activity
GT360_03155	COG0822	iron-sulfur transferase activity
GT360_03170	COG0443	Heat shock 70 kDa protein
GT360_03175	COG0633	Ferredoxin
GT360_03180	COG2975	iron-sulfur cluster assembly
GT360_03205	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GT360_03210	COG0124	histidyl-tRNA synthetase
GT360_03215	COG2976	Protein conserved in bacteria
GT360_03220	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GT360_03225	COG1160	GTP binding
GT360_03245	COG0517	IMP dehydrogenase activity
GT360_03245	COG0516	GMP reductase activity
GT360_03250	COG0519	Catalyzes the synthesis of GMP from XMP
GT360_03250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GT360_03280	COG0398	Pfam SNARE associated Golgi protein
GT360_03285	COG4134	Bacterial extracellular solute-binding protein
GT360_03290	COG4135	transport system, permease component
GT360_03295	COG4136	ATPase activity
GT360_03300	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GT360_03305	COG0517	IMP dehydrogenase activity
GT360_03310	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GT360_03315	COG0343	queuine tRNA-ribosyltransferase activity
GT360_03320	COG1862	Preprotein translocase
GT360_03325	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GT360_03330	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GT360_03350	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
GT360_03360	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GT360_03375	COG0745	RESPONSE REGULATOR receiver
GT360_03380	COG5002	protein histidine kinase activity
GT360_03390	COG0248	Ppx GppA phosphatase
GT360_03395	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GT360_03405	COG0573	inorganic phosphate transmembrane transporter activity
GT360_03410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GT360_03415	COG0704	Plays a role in the regulation of phosphate uptake
GT360_03425	COG3141	response to X-ray
GT360_03430	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GT360_03435	COG1074	ATP-dependent DNA helicase activity
GT360_03440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GT360_03460	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GT360_03465	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GT360_03470	COG2166	iron-sulfur cluster assembly
GT360_03475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GT360_03480	COG0693	protein deglycase activity
GT360_03485	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GT360_03490	COG3248	Nucleoside-binding outer membrane protein
GT360_03505	COG1595	DNA-templated transcription, initiation
GT360_03530	COG2813	Specifically methylates the guanine in position
GT360_03535	COG0271	Belongs to the BolA IbaG family
GT360_03540	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GT360_03545	COG1805	sodium ion transport
GT360_03555	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GT360_03560	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GT360_03565	COG2871	sodium ion transport
GT360_03570	COG1477	protein flavinylation
GT360_03585	COG4969	Belongs to the N-Me-Phe pilin family
GT360_03605	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GT360_03615	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GT360_03620	COG0583	DNA-binding transcription factor activity
GT360_03625	COG0590	tRNA wobble adenosine to inosine editing
GT360_03630	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GT360_03635	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GT360_03635	COG0047	phosphoribosylformylglycinamidine synthase activity
GT360_03665	COG1720	tRNA m6t6A37 methyltransferase activity
GT360_03670	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GT360_03675	COG1671	Belongs to the UPF0178 family
GT360_03700	COG3098	single-species biofilm formation
GT360_03705	COG0564	pseudouridine synthase activity
GT360_03710	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GT360_03715	COG0142	geranyltranstransferase activity
GT360_03725	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GT360_03735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GT360_03735	COG0301	tRNA thio-modification
GT360_03740	COG0583	DNA-binding transcription factor activity
GT360_03750	COG2363	Small membrane protein
GT360_03765	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GT360_03770	COG1611	Belongs to the LOG family
GT360_03775	COG3706	GGDEF domain
GT360_03795	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GT360_03800	COG1464	Belongs to the NlpA lipoprotein family
GT360_03805	COG2011	ABC-type metal ion transport system permease component
GT360_03810	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GT360_03815	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GT360_03820	COG1609	Transcriptional regulator
GT360_03825	COG1263	PTS System
GT360_03825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GT360_03830	COG0366	Alpha amylase catalytic
GT360_03865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT360_03870	COG0840	transmembrane signaling receptor activity
GT360_03895	COG0737	Belongs to the 5'-nucleotidase family
GT360_03900	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GT360_03905	COG0583	DNA-binding transcription factor activity
GT360_03915	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GT360_03920	COG0321	lipoyl(octanoyl) transferase activity
GT360_03925	COG2921	Belongs to the UPF0250 family
GT360_03930	COG1686	Belongs to the peptidase S11 family
GT360_03935	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GT360_03940	COG0772	Belongs to the SEDS family
GT360_03945	COG0768	penicillin binding
GT360_03950	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GT360_03955	COG0799	negative regulation of ribosome biogenesis
GT360_03960	COG1466	dna polymerase III delta subunit
GT360_03965	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GT360_03970	COG0495	leucyl-tRNA aminoacylation
GT360_03975	COG2888	peptidyl-tyrosine sulfation
GT360_03980	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GT360_03985	COG4535	Mg2 and Co2 transporter CorC
GT360_03995	COG1702	phosphate starvation-inducible protein PhoH
GT360_04005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GT360_04010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT360_04025	COG2190	(PTS) system
GT360_04035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT360_04040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GT360_04045	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GT360_04050	COG3115	cell septum assembly
GT360_04055	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GT360_04080	COG0330	HflC and HflK could
GT360_04085	COG3118	belongs to the thioredoxin family
GT360_04090	COG0300	oxidoreductase activity
GT360_04095	COG1090	epimerase
GT360_04115	COG0517	IMP dehydrogenase activity
GT360_04120	COG0622	Phosphoesterase
GT360_04130	COG3710	Transcriptional regulator
GT360_04135	COG0326	Molecular chaperone. Has ATPase activity
GT360_04145	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GT360_04155	COG0367	asparagine synthase
GT360_04160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GT360_04160	COG4651	solute:proton antiporter activity
GT360_04165	COG1846	Transcriptional regulator
GT360_04165	COG1940	carbohydrate kinase activity
GT360_04170	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GT360_04175	COG2190	(PTS) system
GT360_04175	COG1263	PTS System
GT360_04175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GT360_04185	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GT360_04190	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GT360_04210	COG2890	protein-(glutamine-N5) methyltransferase activity
GT360_04220	COG2912	Transglutaminase-like superfamily
GT360_04225	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GT360_04255	COG1393	Belongs to the ArsC family
GT360_04260	COG4783	chaperone-mediated protein folding
GT360_04280	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GT360_04285	COG2716	regulation of RNA biosynthetic process
GT360_04315	COG1393	Belongs to the ArsC family
GT360_04320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GT360_04345	COG2837	iron assimilation
GT360_04355	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GT360_04360	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GT360_04370	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GT360_04380	COG1516	flagellar protein fliS
GT360_04390	COG4191	Histidine kinase
GT360_04400	COG1677	Flagellar hook-basal body complex protein FliE
GT360_04410	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GT360_04435	COG1580	Controls the rotational direction of flagella during chemotaxis
GT360_04460	COG1987	bacterial-type flagellum assembly
GT360_04465	COG1684	flagellar biosynthetic protein fliR
GT360_04475	COG2840	Smr protein MutS2
GT360_04480	COG2890	protein-(glutamine-N5) methyltransferase activity
GT360_04485	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GT360_04490	COG2860	membrane
GT360_04495	COG2205	protein histidine kinase activity
GT360_04500	COG0745	RESPONSE REGULATOR receiver
GT360_04510	COG3101	peptidyl-lysine hydroxylation
GT360_04525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT360_04525	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GT360_04530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GT360_04535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT360_04540	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GT360_04550	COG0101	tRNA pseudouridine synthase activity
GT360_04560	COG0285	dihydrofolate synthase activity
GT360_04565	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GT360_04570	COG1286	toxin biosynthetic process
GT360_04575	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GT360_04580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GT360_04585	COG1121	(ABC) transporter
GT360_04590	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GT360_04600	COG1918	ferrous iron import across plasma membrane
GT360_04605	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GT360_04625	COG0018	arginyl-trna synthetase
GT360_04630	COG3102	Protein conserved in bacteria
GT360_04635	COG1025	Belongs to the peptidase M16 family
GT360_04640	COG2062	phosphohistidine phosphatase, SixA
GT360_04645	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GT360_04670	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GT360_04675	COG0784	Response regulator, receiver
GT360_04675	COG0643	Histidine kinase
GT360_04675	COG2198	Histidine kinase
GT360_04680	COG2201	protein-glutamate methylesterase activity
GT360_04685	COG1192	Involved in chromosome partitioning
GT360_04695	COG0835	chemotaxis
GT360_04705	COG4133	protoheme IX ABC transporter activity
GT360_04710	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GT360_04715	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GT360_04730	COG1138	Cytochrome C-type biogenesis protein
GT360_04735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GT360_04740	COG3088	subunit of a heme lyase
GT360_04740	COG4235	cytochrome complex assembly
GT360_04745	COG4235	cytochrome complex assembly
GT360_04745	COG3088	subunit of a heme lyase
GT360_04750	COG2853	Lipoprotein
GT360_04755	COG2067	long-chain fatty acid transport protein
GT360_04760	COG0659	secondary active sulfate transmembrane transporter activity
GT360_04765	COG1530	ribonuclease E activity
GT360_04770	COG0564	pseudouridine synthase activity
GT360_04775	COG0424	maF-like protein
GT360_04780	COG1399	metal-binding, possibly nucleic acid-binding protein
GT360_04795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GT360_04825	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GT360_04830	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GT360_04835	COG0470	DNA polymerase III
GT360_04840	COG0084	hydrolase, TatD family'
GT360_04845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GT360_04845	COG1263	PTS System
GT360_04860	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GT360_04865	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GT360_04870	COG0436	Aminotransferase
GT360_04875	COG1169	isochorismate synthase
GT360_04890	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GT360_04900	COG0318	PFAM AMP-dependent synthetase and ligase
GT360_04910	COG0477	Major facilitator Superfamily
GT360_04930	COG1028	Short-chain dehydrogenase reductase Sdr
GT360_04935	COG0616	signal peptide processing
GT360_04945	COG1757	Na H antiporter
GT360_04955	COG2814	Major facilitator Superfamily
GT360_04975	COG3923	Primosomal replication protein n
GT360_04985	COG1199	ATP-dependent helicase activity
GT360_05000	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GT360_05005	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GT360_05015	COG2226	methyltransferase
GT360_05020	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GT360_05045	COG0300	oxidoreductase activity
GT360_05060	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GT360_05085	COG0601	transmembrane transport
GT360_05090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT360_05095	COG0444	Belongs to the ABC transporter superfamily
GT360_05105	COG0435	Glutathione S-transferase
GT360_05130	COG4667	esterase of the alpha-beta hydrolase superfamily
GT360_05135	COG1940	carbohydrate kinase activity
GT360_05140	COG0835	chemotaxis
GT360_05140	COG0784	Response regulator, receiver
GT360_05145	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GT360_05150	COG2915	High frequency lysogenization protein hflD homolog
GT360_05155	COG0482	sulfurtransferase activity
GT360_05160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT360_05165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GT360_05180	COG1252	NADH dehydrogenase
GT360_05190	COG4232	protein-disulfide reductase activity
GT360_05195	COG0492	ferredoxin-NADP+ reductase activity
GT360_05195	COG3118	belongs to the thioredoxin family
GT360_05215	COG2226	methyltransferase
GT360_05220	COG0676	glucose-6-phosphate 1-epimerase activity
GT360_05225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GT360_05230	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GT360_05240	COG3139	Protein of unknown function (DUF1315)
GT360_05245	COG0252	asparaginase activity
GT360_05250	COG0616	signal peptide processing
GT360_05255	COG1902	pentaerythritol trinitrate reductase activity
GT360_05255	COG0446	pyridine nucleotide-disulphide oxidoreductase
GT360_05265	COG0788	formyltetrahydrofolate deformylase activity
GT360_05270	COG1199	ATP-dependent helicase activity
GT360_05275	COG1214	PFAM Peptidase M22, glycoprotease
GT360_05285	COG0596	Alpha beta hydrolase
GT360_05290	COG0318	PFAM AMP-dependent synthetase and ligase
GT360_05295	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GT360_05310	COG1760	l-serine dehydratase
GT360_05315	COG0814	amino acid
GT360_05325	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GT360_05340	COG3106	COG3106 Predicted ATPase
GT360_05355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GT360_05375	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GT360_05380	COG2989	Protein conserved in bacteria
GT360_05385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GT360_05425	COG0443	Heat shock 70 kDa protein
GT360_05430	COG0443	Heat shock 70 kDa protein
GT360_05445	COG2873	o-acetylhomoserine
GT360_05460	COG0189	ligase activity
GT360_05460	COG4067	protein conserved in archaea
GT360_05465	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GT360_05470	COG4988	ABC transporter
GT360_05475	COG0492	ferredoxin-NADP+ reductase activity
GT360_05485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GT360_05495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GT360_05505	COG0366	Alpha amylase catalytic
GT360_05520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT360_05560	COG0523	cobalamin synthesis protein
GT360_05565	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GT360_05575	COG1129	ABC transporter
GT360_05595	COG0159	tryptophan synthase activity
GT360_05605	COG0134	indole-3-glycerol-phosphate synthase activity
GT360_05605	COG0135	phosphoribosylanthranilate isomerase activity
GT360_05610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GT360_05615	COG0512	Glutamine amidotransferase of anthranilate synthase
GT360_05620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GT360_05630	COG0613	PHP domain protein
GT360_05635	COG0009	L-threonylcarbamoyladenylate synthase
GT360_05640	COG1187	pseudouridine synthase activity
GT360_05655	COG0484	heat shock protein binding
GT360_05670	COG0277	FAD linked oxidase domain protein
GT360_05670	COG0247	lactate metabolic process
GT360_05690	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GT360_05700	COG0417	DNA replication proofreading
GT360_05705	COG2197	response regulator
GT360_05710	COG0322	excinuclease ABC activity
GT360_05750	COG0072	phenylalanine-tRNA ligase activity
GT360_05750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GT360_05785	COG1451	nucleotide metabolic process
GT360_05795	COG0004	ammonium transporteR
GT360_05800	COG0737	Belongs to the 5'-nucleotidase family
GT360_05805	COG3063	Type IV pilus biogenesis stability protein PilW
GT360_05810	COG0840	transmembrane signaling receptor activity
GT360_05820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GT360_05825	COG1309	transcriptional regulator
GT360_05840	COG2723	6-phospho-beta-galactosidase activity
GT360_05845	COG1263	PTS System
GT360_05845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GT360_05915	COG2354	Protein conserved in bacteria
GT360_05940	COG0242	peptide deformylase activity
GT360_05945	COG0784	Response regulator, receiver
GT360_05945	COG2205	protein histidine kinase activity
GT360_05975	COG0583	DNA-binding transcription factor activity
GT360_06015	COG2207	Transcriptional regulator
GT360_06015	COG3708	Transcriptional regulator
GT360_06030	COG0546	phosphoglycolate phosphatase activity
GT360_06050	COG4948	Mandelate Racemase Muconate Lactonizing
GT360_06055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GT360_06080	COG0531	amino acid
GT360_06095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT360_06100	COG0583	DNA-binding transcription factor activity
GT360_06130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GT360_06135	COG0583	DNA-binding transcription factor activity
GT360_06150	COG1280	lysine exporter protein (LysE YggA)
GT360_06170	COG2860	membrane
GT360_06210	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GT360_06240	COG1116	anion transmembrane transporter activity
GT360_06240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GT360_06245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT360_06250	COG1116	anion transmembrane transporter activity
GT360_06255	COG0786	glutamate:sodium symporter activity
GT360_06260	COG1566	PFAM secretion protein HlyD family protein
GT360_06270	COG1215	transferase activity, transferring glycosyl groups
GT360_06285	COG0583	DNA-binding transcription factor activity
GT360_06305	COG2356	endonuclease I
GT360_06310	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
GT360_06425	COG4191	Histidine kinase
GT360_06430	COG4657	Part of a membrane complex involved in electron transport
GT360_06435	COG2878	Part of a membrane complex involved in electron transport
GT360_06440	COG4656	Part of a membrane complex involved in electron transport
GT360_06445	COG4658	electron transport chain
GT360_06470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GT360_06470	COG1263	PTS System
GT360_06510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GT360_06510	COG3153	acetyltransferase
GT360_06515	COG0405	Gamma-glutamyltransferase
GT360_06525	COG0456	acetyltransferase
GT360_06575	COG1785	Belongs to the alkaline phosphatase family
GT360_06595	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GT360_06605	COG1472	Belongs to the glycosyl hydrolase 3 family
GT360_06620	COG1388	LysM domain
GT360_06620	COG0791	NLP P60 protein
GT360_06630	COG1846	Transcriptional regulator
GT360_06635	COG0583	DNA-binding transcription factor activity
GT360_06640	COG2249	NAD(P)H dehydrogenase (quinone) activity
GT360_06695	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GT360_06700	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT360_06705	COG0604	alcohol dehydrogenase
GT360_06705	COG3321	synthase
GT360_06705	COG1028	Short-chain dehydrogenase reductase Sdr
GT360_06710	COG0735	belongs to the Fur family
GT360_06715	COG0523	cobalamin synthesis protein
GT360_06725	COG0395	ABC-type sugar transport system, permease component
GT360_06730	COG1175	transmembrane transport
GT360_06745	COG2186	Transcriptional regulator
GT360_06750	COG1012	belongs to the aldehyde dehydrogenase family
GT360_06755	COG3250	beta-galactosidase activity
GT360_06765	COG4580	involved in the transport of maltose and maltodextrins
GT360_06790	COG3547	Transposase (IS116 IS110 IS902 family)
GT360_06800	COG2186	Transcriptional regulator
GT360_06810	COG2731	YhcH YjgK YiaL family protein
GT360_06815	COG0840	transmembrane signaling receptor activity
GT360_06820	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GT360_06825	COG1063	alcohol dehydrogenase
GT360_06830	COG0246	Mannitol dehydrogenase
GT360_06840	COG0800	Aldolase
GT360_06845	COG4948	Mandelate Racemase Muconate Lactonizing
GT360_06860	COG0534	Mate efflux family protein
GT360_06865	COG0534	Mate efflux family protein
GT360_06875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT360_06880	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT360_06895	COG0148	phosphopyruvate hydratase activity
GT360_06915	COG0765	amino acid transport
GT360_06920	COG0765	amino acid transport
GT360_06930	COG1737	Transcriptional regulator
GT360_06945	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GT360_06960	COG2059	Chromate
GT360_06965	COG2059	Chromate
GT360_06980	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GT360_06985	COG1254	Belongs to the acylphosphatase family
GT360_06990	COG2920	part of a sulfur-relay system
GT360_06995	COG0670	Belongs to the BI1 family
GT360_07000	COG1126	abc transporter atp-binding protein
GT360_07005	COG0765	amino acid transport
GT360_07010	COG4597	amino acid ABC transporter
GT360_07015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT360_07035	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GT360_07040	COG1666	GTP binding
GT360_07045	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GT360_07060	COG2996	Protein conserved in bacteria
GT360_07070	COG3008	intermembrane lipid transfer
GT360_07075	COG2995	paraquat-inducible protein a
GT360_07080	COG1132	(ABC) transporter
GT360_07085	COG1956	GAF domain-containing protein
GT360_07090	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GT360_07105	COG0308	aminopeptidase N
GT360_07120	COG0167	dihydroorotate dehydrogenase activity
GT360_07155	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GT360_07160	COG1067	ATP-dependent peptidase activity
GT360_07165	COG3120	sequence-specific DNA binding
GT360_07350	COG3278	Belongs to the heme-copper respiratory oxidase family
GT360_07365	COG2010	Cytochrome c
GT360_07375	COG2217	Heavy metal translocating P-type atpase
GT360_07390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GT360_07395	COG0589	response to stress
GT360_07400	COG0037	tRNA processing
GT360_07420	COG3842	ATPase activity
GT360_07430	COG1177	transmembrane transport
GT360_07435	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GT360_07445	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GT360_07465	COG1940	carbohydrate kinase activity
GT360_07480	COG0791	NLP P60 protein
GT360_07500	COG0307	riboflavin synthase, alpha
GT360_07505	COG0534	Mate efflux family protein
GT360_07515	COG1793	dna ligase
GT360_07525	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GT360_07530	COG4139	cobalamin transport
GT360_07535	COG2988	succinylglutamate desuccinylase activity
GT360_07540	COG1028	Short-chain dehydrogenase reductase Sdr
GT360_07550	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GT360_07560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GT360_07565	COG0702	epimerase
GT360_07575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT360_07590	COG2925	Exonuclease
GT360_07595	COG1380	Effector of murein hydrolase LrgA
GT360_07600	COG1346	cytolysis
GT360_07605	COG0295	cytidine deaminase activity
GT360_07615	COG0471	metal ion transport
GT360_07620	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GT360_07625	COG1858	cytochrome C peroxidase
GT360_07655	COG1119	ATPase activity
GT360_07660	COG0561	phosphatase activity
GT360_07670	COG0602	queuosine metabolic process
GT360_07695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GT360_07710	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GT360_07720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GT360_07725	COG0583	DNA-binding transcription factor activity
GT360_07750	COG0019	diaminopimelate decarboxylase activity
GT360_07765	COG1320	monovalent cation:proton antiporter activity
GT360_07770	COG2212	antiporter activity
GT360_07775	COG1863	multisubunit Na H antiporter MnhE subunit
GT360_07785	COG1006	Multisubunit Na H antiporter MnhC subunit
GT360_07790	COG2111	Na H antiporter
GT360_07810	COG1136	(ABC) transporter
GT360_07815	COG0534	Mate efflux family protein
GT360_07820	COG0702	epimerase
GT360_07830	COG2814	Major facilitator Superfamily
GT360_07835	COG1187	pseudouridine synthase activity
GT360_07845	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GT360_07855	COG1061	Type III restriction enzyme res subunit
GT360_07860	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GT360_07865	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GT360_07875	COG1280	lysine exporter protein (LysE YggA)
GT360_07880	COG0737	Belongs to the 5'-nucleotidase family
GT360_07905	COG1115	amino acid carrier protein
GT360_07915	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GT360_07930	COG1522	sequence-specific DNA binding
GT360_07955	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GT360_07960	COG0667	Aldo Keto reductase
GT360_07980	COG1741	Belongs to the pirin family
GT360_08000	COG2017	converts alpha-aldose to the beta-anomer
GT360_08005	COG1653	transport
GT360_08010	COG1175	transmembrane transport
GT360_08015	COG0395	ABC-type sugar transport system, permease component
GT360_08020	COG3842	ATPase activity
GT360_08030	COG0840	transmembrane signaling receptor activity
GT360_08055	COG1410	methionine synthase
GT360_08055	COG0646	methionine synthase
GT360_08060	COG3171	Protein conserved in bacteria
GT360_08075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GT360_08090	COG1012	belongs to the aldehyde dehydrogenase family
GT360_08095	COG1757	Na H antiporter
GT360_08120	COG0531	amino acid
GT360_08125	COG2957	Belongs to the agmatine deiminase family
GT360_08135	COG0702	epimerase
GT360_08150	COG0488	(ABC) transporter
GT360_08160	COG2358	TRAP transporter, solute receptor (TAXI family
GT360_08165	COG1162	GTPase activity
GT360_08170	COG3596	GTP binding
GT360_08175	COG0513	Belongs to the DEAD box helicase family
GT360_08190	COG4176	ABC-type proline glycine betaine transport system permease component
GT360_08195	COG3448	diguanylate cyclase activity
GT360_08195	COG4175	Glycine betaine
GT360_08205	COG0625	glutathione transferase activity
GT360_08230	COG0372	Belongs to the citrate synthase family
GT360_08235	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GT360_08250	COG0583	DNA-binding transcription factor activity
GT360_08255	COG2259	Doxx family
GT360_08260	COG3384	dioxygenase
GT360_08280	COG2814	Major facilitator Superfamily
GT360_08335	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GT360_08335	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GT360_08345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT360_08390	COG0583	DNA-binding transcription factor activity
GT360_08395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GT360_08410	COG1846	Transcriptional regulator
GT360_08420	COG1294	oxidase, subunit
GT360_08425	COG1271	oxidase subunit
GT360_08445	COG3706	GGDEF domain
GT360_08480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT360_08485	COG1132	(ABC) transporter
GT360_08500	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT360_08520	COG0582	viral genome integration into host DNA
GT360_08565	COG1012	belongs to the aldehyde dehydrogenase family
GT360_08570	COG1024	Enoyl-CoA hydratase
GT360_08575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT360_08615	COG0778	Nitroreductase
GT360_08630	COG3313	Fe-S protein
GT360_08645	COG0564	pseudouridine synthase activity
GT360_08655	COG0626	cystathionine gamma-synthase activity
GT360_08665	COG0519	Catalyzes the synthesis of GMP from XMP
GT360_08675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT360_08695	COG1842	Phage shock protein A
GT360_08700	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GT360_08710	COG4168	peptide transport system, permease
GT360_08715	COG4171	peptide transport system, permease
GT360_08725	COG4172	Belongs to the ABC transporter superfamily
GT360_08745	COG1309	transcriptional regulator
GT360_08750	COG0017	Asparaginyl-tRNA synthetase
GT360_08755	COG3706	GGDEF domain
GT360_08760	COG1448	Aminotransferase
GT360_08765	COG0281	malic enzyme
GT360_08775	COG2949	membrane
GT360_08785	COG0786	glutamate:sodium symporter activity
GT360_08790	COG2261	transglycosylase associated protein
GT360_08800	COG1643	Atp-dependent helicase
GT360_08805	COG2217	Heavy metal translocating P-type atpase
GT360_08820	COG4608	Belongs to the ABC transporter superfamily
GT360_08855	COG0513	Belongs to the DEAD box helicase family
GT360_08885	COG1366	Belongs to the anti-sigma-factor antagonist family
GT360_08890	COG2885	chlorophyll binding
GT360_08915	COG2204	response regulator
GT360_08925	COG1166	arginine decarboxylase activity
GT360_08930	COG0010	Belongs to the arginase family
GT360_08960	COG0438	transferase activity, transferring glycosyl groups
GT360_08970	COG0297	glycogen (starch) synthase activity
GT360_08980	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GT360_09015	COG1454	alcohol dehydrogenase
GT360_09015	COG1012	belongs to the aldehyde dehydrogenase family
GT360_09020	COG3040	lipid binding
GT360_09025	COG2195	Cleaves the N-terminal amino acid of tripeptides
GT360_09050	COG2233	PERMEase
GT360_09055	COG2133	pyrroloquinoline quinone binding
GT360_09065	COG3706	GGDEF domain
GT360_09075	COG2169	Transcriptional regulator
GT360_09080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GT360_09085	COG1301	dicarboxylic acid transport
GT360_09090	COG0415	Belongs to the DNA photolyase family
GT360_09100	COG1607	acyl-coa hydrolase
GT360_09105	COG2350	Protein conserved in bacteria
GT360_09135	COG0390	transport system, permease component
GT360_09140	COG1794	racemase activity, acting on amino acids and derivatives
GT360_09150	COG1227	inorganic diphosphatase activity
GT360_09160	COG2951	lytic endotransglycosylase activity
GT360_09165	COG3100	YcgL domain-containing protein
GT360_09175	COG2894	cell division
GT360_09180	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GT360_09185	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GT360_09195	COG3852	Histidine kinase
GT360_09210	COG3070	regulator of competence-specific genes
GT360_09220	COG2431	L-lysine efflux transmembrane transporter activity
GT360_09230	COG0076	glutamate decarboxylase activity
GT360_09235	COG1737	Transcriptional regulator
GT360_09240	COG1454	alcohol dehydrogenase
GT360_09245	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GT360_09255	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GT360_09255	COG0140	phosphoribosyl-ATP diphosphatase activity
GT360_09265	COG1132	(ABC) transporter
GT360_09270	COG0748	coenzyme F420 binding
GT360_09275	COG3721	Heme iron utilization protein
GT360_09285	COG4558	Periplasmic binding protein
GT360_09290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GT360_09295	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GT360_09305	COG4206	TonB-dependent receptor
GT360_09330	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GT360_09335	COG0131	Imidazoleglycerol-phosphate dehydratase
GT360_09335	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GT360_09340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GT360_09345	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GT360_09360	COG0784	Response regulator, receiver
GT360_09360	COG2205	protein histidine kinase activity
GT360_09370	COG2199	diguanylate cyclase activity
GT360_09370	COG2200	EAL domain
GT360_09370	COG2202	Pas domain
GT360_09430	COG3150	esterase
GT360_09450	COG0537	adenosine 5'-monophosphoramidase activity
GT360_09465	COG2186	Transcriptional regulator
GT360_09480	COG1674	ftsk spoiiie
GT360_09485	COG1522	sequence-specific DNA binding
GT360_09490	COG0686	Belongs to the AlaDH PNT family
GT360_09500	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GT360_09505	COG0857	belongs to the CobB CobQ family
GT360_09505	COG0280	phosphate acetyltransferase
GT360_09515	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GT360_09520	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GT360_09525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GT360_09530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT360_09535	COG1116	anion transmembrane transporter activity
GT360_09540	COG0351	phosphomethylpyrimidine kinase
GT360_09545	COG0243	molybdopterin cofactor binding
GT360_09550	COG1648	precorrin-2 dehydrogenase activity
GT360_09550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GT360_09555	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GT360_09565	COG2223	nitrite transmembrane transporter activity
GT360_09570	COG2815	serine threonine protein kinase
GT360_09570	COG0515	serine threonine protein kinase
GT360_09585	COG3104	oligopeptide transport
GT360_09600	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GT360_09605	COG0583	DNA-binding transcription factor activity
GT360_09620	COG1032	radical SAM domain protein
GT360_09630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT360_09665	COG3005	denitrification pathway
GT360_09670	COG4459	periplasmic nitrate reductase
GT360_09685	COG0542	response to heat
GT360_09690	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GT360_09695	COG1278	Cold shock
GT360_09710	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GT360_09715	COG1960	acyl-CoA dehydrogenase activity
GT360_09730	COG0840	transmembrane signaling receptor activity
GT360_09740	COG4160	amino acid transport
GT360_09770	COG1882	Formate acetyltransferase
GT360_09780	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GT360_09795	COG2766	serine protein kinase
GT360_09800	COG2718	Belongs to the UPF0229 family
GT360_09805	COG2719	SpoVR family
GT360_09815	COG2835	tetraacyldisaccharide 4'-kinase activity
GT360_09825	COG1132	(ABC) transporter
GT360_09840	COG4591	ABC-type transport system involved in lipoprotein release permease component
GT360_09845	COG1136	(ABC) transporter
GT360_09850	COG4591	ABC-type transport system involved in lipoprotein release permease component
GT360_09860	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GT360_09885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GT360_09890	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GT360_09905	COG1028	Short-chain dehydrogenase reductase Sdr
GT360_09910	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GT360_09915	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GT360_09920	COG0625	glutathione transferase activity
GT360_09930	COG2211	Major facilitator Superfamily
GT360_09940	COG4580	involved in the transport of maltose and maltodextrins
GT360_09950	COG3250	beta-galactosidase activity
GT360_09955	COG1609	Transcriptional regulator
GT360_09965	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GT360_09980	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GT360_09985	COG2832	Protein of unknown function (DUF454)
GT360_09995	COG0745	RESPONSE REGULATOR receiver
GT360_10000	COG0583	DNA-binding transcription factor activity
GT360_10005	COG0778	Nitroreductase
GT360_10010	COG1024	Enoyl-CoA hydratase
GT360_10010	COG1250	3-hydroxyacyl-CoA dehydrogenase
GT360_10015	COG0183	Belongs to the thiolase family
GT360_10020	COG1595	DNA-templated transcription, initiation
GT360_10030	COG2067	long-chain fatty acid transport protein
GT360_10035	COG1012	belongs to the aldehyde dehydrogenase family
GT360_10035	COG1454	alcohol dehydrogenase
GT360_10040	COG2095	MarC family integral membrane protein
GT360_10045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GT360_10050	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GT360_10075	COG3083	sulfuric ester hydrolase activity
GT360_10115	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GT360_10120	COG1946	Acyl-CoA thioesterase
GT360_10130	COG1522	sequence-specific DNA binding
GT360_10155	COG0572	uridine kinase
GT360_10160	COG0489	protein tyrosine kinase activity
GT360_10185	COG0617	tRNA 3'-terminal CCA addition
GT360_10185	COG0517	IMP dehydrogenase activity
GT360_10185	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GT360_10190	COG0314	molybdopterin synthase activity
GT360_10195	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GT360_10200	COG0315	cyclic pyranopterin monophosphate synthase activity
GT360_10205	COG0521	Mo-molybdopterin cofactor biosynthetic process
GT360_10210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GT360_10215	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GT360_10220	COG2198	Histidine kinase
GT360_10230	COG0556	nucleotide-excision repair
GT360_10240	COG4657	Part of a membrane complex involved in electron transport
GT360_10245	COG2878	Part of a membrane complex involved in electron transport
GT360_10250	COG4656	Part of a membrane complex involved in electron transport
GT360_10255	COG4658	electron transport chain
GT360_10265	COG4660	Part of a membrane complex involved in electron transport
GT360_10270	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GT360_10285	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GT360_10290	COG0346	lactoylglutathione lyase activity
GT360_10300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GT360_10305	COG2056	Na+-H+ antiporter family
GT360_10320	COG0508	dehydrogenase complex catalyzes the overall conversion of
GT360_10325	COG0567	Dehydrogenase, E1 component
GT360_10335	COG1053	succinate dehydrogenase
GT360_10340	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GT360_10355	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GT360_10370	COG0149	triose-phosphate isomerase activity
GT360_10380	COG2376	Dihydroxyacetone kinase
GT360_10385	COG0698	ribose 5-phosphate isomerase
GT360_10395	COG3959	Transketolase, thiamine diphosphate binding domain
GT360_10400	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GT360_10425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT360_10430	COG0033	Phosphoglucomutase
GT360_10435	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GT360_10440	COG0596	Alpha beta hydrolase
GT360_10450	COG0716	FMN binding
GT360_10460	COG0735	belongs to the Fur family
GT360_10465	COG0193	aminoacyl-tRNA hydrolase activity
GT360_10470	COG0012	GTP binding
GT360_10585	COG3951	Flagellar rod assembly protein muramidase FlgJ
GT360_10585	COG1705	Flagellar rod assembly protein muramidase FlgJ
GT360_10595	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GT360_10605	COG4787	bacterial-type flagellum-dependent cell motility
GT360_10610	COG1749	Flagellar hook protein flgE
GT360_10625	COG1815	bacterial-type flagellum-dependent cell motility
GT360_10635	COG0784	Response regulator, receiver
GT360_10635	COG0835	chemotaxis
GT360_10640	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
GT360_10690	COG2608	mercury ion transmembrane transporter activity
GT360_10690	COG2217	Heavy metal translocating P-type atpase
GT360_10725	COG2840	Smr protein MutS2
GT360_10730	COG1187	pseudouridine synthase activity
GT360_10735	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GT360_10740	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GT360_10745	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GT360_10750	COG0121	glutamine amidotransferase
GT360_10760	COG1960	acyl-CoA dehydrogenase activity
GT360_10780	COG2199	diguanylate cyclase activity
GT360_10790	COG2226	methyltransferase
GT360_10800	COG1388	LysM domain
GT360_10800	COG0741	lytic transglycosylase activity
GT360_10810	COG3021	interspecies interaction between organisms
GT360_10815	COG0347	Belongs to the P(II) protein family
GT360_10835	COG0587	DNA-directed DNA polymerase activity
GT360_10855	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GT360_10860	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GT360_10865	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GT360_10870	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GT360_10875	COG0750	zinc metalloprotease
GT360_10885	COG0575	Belongs to the CDS family
GT360_10890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GT360_10895	COG0233	cytoplasmic translational termination
GT360_10900	COG0528	UMP kinase activity
GT360_10915	COG0024	Methionine aminopeptidase
GT360_10930	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GT360_10960	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GT360_10960	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GT360_10965	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GT360_10970	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GT360_10990	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GT360_10995	COG2252	PERMEase
GT360_11000	COG2195	Cleaves the N-terminal amino acid of tripeptides
GT360_11005	COG4067	protein conserved in archaea
GT360_11005	COG0189	ligase activity
GT360_11010	COG0189	ligase activity
GT360_11020	COG0733	neurotransmitter:sodium symporter activity
GT360_11030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GT360_11045	COG1301	dicarboxylic acid transport
GT360_11050	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GT360_11060	COG0497	DNA recombination
GT360_11065	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GT360_11070	COG2914	Belongs to the UPF0125 (RnfH) family
GT360_11075	COG2867	negative regulation of translational initiation
GT360_11090	COG0582	viral genome integration into host DNA
GT360_11135	COG0582	viral genome integration into host DNA
GT360_11150	COG1132	(ABC) transporter
GT360_11155	COG0514	ATP-dependent DNA helicase (RecQ)
GT360_11175	COG1162	GTPase activity
GT360_11180	COG1454	alcohol dehydrogenase
GT360_11190	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GT360_11195	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GT360_11210	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GT360_11215	COG0804	urea catabolic process
GT360_11220	COG0832	Belongs to the urease beta subunit family
GT360_11225	COG0831	urea catabolic process
GT360_11250	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT360_11265	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GT360_11270	COG0583	DNA-binding transcription factor activity
GT360_11275	COG0450	alkyl hydroperoxide reductase
GT360_11280	COG2171	N-acyltransferase activity
GT360_11285	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GT360_11290	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GT360_11300	COG1609	Transcriptional regulator
GT360_11305	COG1653	transport
GT360_11310	COG0395	ABC-type sugar transport system, permease component
GT360_11315	COG1175	transmembrane transport
GT360_11320	COG3842	ATPase activity
GT360_11330	COG0583	DNA-binding transcription factor activity
GT360_11335	COG2059	Chromate
GT360_11385	COG4964	Belongs to the GSP D family
GT360_11410	COG2169	Transcriptional regulator
GT360_11415	COG1022	Amp-dependent synthetase and ligase
GT360_11420	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GT360_11425	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GT360_11435	COG0560	Phosphoserine phosphatase
GT360_11445	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GT360_11455	COG0730	response to heat
GT360_11470	COG3066	DNA modification
GT360_11485	COG2204	response regulator
GT360_11490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GT360_11510	COG0513	Belongs to the DEAD box helicase family
GT360_11530	COG3153	acetyltransferase
GT360_11535	COG3154	lipid carrier protein
GT360_11545	COG0826	peptidase U32
GT360_11550	COG0826	peptidase U32
GT360_11560	COG0534	Mate efflux family protein
GT360_11580	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GT360_11600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GT360_11605	COG2860	membrane
GT360_11610	COG0813	purine-nucleoside phosphorylase activity
GT360_11620	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GT360_11635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GT360_11640	COG0084	hydrolase, TatD family'
GT360_11655	COG1115	amino acid carrier protein
GT360_11670	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GT360_11675	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GT360_11685	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GT360_11690	COG0083	homoserine kinase activity
GT360_11705	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT360_11715	COG0745	RESPONSE REGULATOR receiver
GT360_11725	COG2198	Histidine kinase
GT360_11725	COG5002	protein histidine kinase activity
GT360_11725	COG0784	Response regulator, receiver
GT360_11730	COG1242	4 iron, 4 sulfur cluster binding
GT360_11735	COG0069	glutamate synthase activity
GT360_11735	COG0067	glutamate synthase
GT360_11735	COG0070	glutamate synthase
GT360_11745	COG0069	glutamate synthase activity
GT360_11745	COG0067	glutamate synthase
GT360_11745	COG0070	glutamate synthase
GT360_11750	COG0493	'glutamate synthase
GT360_11775	COG0195	Participates in both transcription termination and antitermination
GT360_11780	COG0779	Required for maturation of 30S ribosomal subunits
GT360_11795	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GT360_11800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GT360_11805	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GT360_11810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GT360_11820	COG1534	Rna-binding protein
GT360_11825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GT360_11835	COG2027	D-alanyl-D-alanine carboxypeptidase
GT360_11845	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GT360_11850	COG0739	heme binding
GT360_11860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT360_11865	COG0316	Belongs to the HesB IscA family
GT360_11870	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GT360_11875	COG0628	permease
GT360_11885	COG2205	protein histidine kinase activity
GT360_11885	COG0784	Response regulator, receiver
GT360_11890	COG0747	negative chemotaxis
GT360_11900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT360_11905	COG0444	Belongs to the ABC transporter superfamily
GT360_11910	COG4608	Belongs to the ABC transporter superfamily
GT360_11920	COG2971	BadF BadG BcrA BcrD
GT360_11935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GT360_11940	COG3842	ATPase activity
GT360_11950	COG1840	ABC-type Fe3 transport system, periplasmic component
GT360_11955	COG0004	ammonium transporteR
GT360_11970	COG3835	regulator
GT360_11975	COG2610	gluconate transmembrane transporter activity
GT360_11980	COG1929	Belongs to the glycerate kinase type-1 family
GT360_11985	COG1049	propionate catabolic process, 2-methylcitrate cycle
GT360_11990	COG1752	Esterase of the alpha-beta hydrolase superfamily
GT360_11995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GT360_12000	COG1643	Atp-dependent helicase
GT360_12010	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GT360_12015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GT360_12025	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GT360_12030	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GT360_12040	COG0842	Transport permease protein
GT360_12045	COG1131	(ABC) transporter
GT360_12050	COG0659	secondary active sulfate transmembrane transporter activity
GT360_12055	COG0288	reversible hydration of carbon dioxide
GT360_12060	COG0795	lipopolysaccharide-transporting ATPase activity
GT360_12065	COG0795	lipopolysaccharide-transporting ATPase activity
GT360_12075	COG2927	DNA polymerase III (CHI subunit)
GT360_12080	COG0525	valine-tRNA ligase activity
GT360_12095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GT360_12100	COG0508	dehydrogenase complex catalyzes the overall conversion of
GT360_12105	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GT360_12110	COG2186	Transcriptional regulator
GT360_12115	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GT360_12120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GT360_12125	COG4974	Belongs to the 'phage' integrase family
GT360_12130	COG0716	FMN binding
GT360_12140	COG0157	Belongs to the NadC ModD family
GT360_12150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GT360_12155	COG1459	type II secretion system
GT360_12165	COG0237	dephospho-CoA kinase activity
GT360_12170	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GT360_12195	COG0228	four-way junction DNA binding
GT360_12200	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GT360_12205	COG4137	Cytochrome C assembly protein
GT360_12210	COG4536	flavin adenine dinucleotide binding
GT360_12215	COG1854	S-ribosylhomocysteine lyase activity
GT360_12230	COG0612	Peptidase, M16
GT360_12235	COG1238	metal cluster binding
GT360_12240	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GT360_12245	COG5016	pyruvate
GT360_12245	COG0511	ligase activity, forming carbon-carbon bonds
GT360_12250	COG3630	sodium ion export across plasma membrane
GT360_12310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GT360_12320	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GT360_12325	COG1546	Belongs to the CinA family
GT360_12330	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GT360_12335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GT360_12355	COG0585	pseudouridine synthase activity
GT360_12370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GT360_12380	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GT360_12385	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GT360_12390	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GT360_12395	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GT360_12400	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GT360_12405	COG1610	YqeY-like protein
GT360_12410	COG0358	DNA primase activity
GT360_12430	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GT360_12475	COG0582	viral genome integration into host DNA
GT360_12480	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GT360_12495	COG0363	glucosamine-6-phosphate deaminase activity
GT360_12500	COG3722	fumarate hydratase activity
GT360_12505	COG0246	Mannitol dehydrogenase
GT360_12510	COG2213	PTS system mannitol-specific
GT360_12510	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT360_12515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT360_12520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GT360_12525	COG1349	DNA-binding transcription factor activity
GT360_12530	COG0469	pyruvate kinase activity
GT360_12535	COG3706	GGDEF domain
GT360_12545	COG0668	transmembrane transport
GT360_12550	COG0191	fructose-bisphosphate aldolase activity
GT360_12570	COG2235	arginine
GT360_12575	COG0312	modulator of DNA gyrase
GT360_12580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GT360_12585	COG3164	Protein of unknown function
GT360_12590	COG1530	ribonuclease E activity
GT360_12595	COG0424	maF-like protein
GT360_12600	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GT360_12605	COG1792	Involved in formation and maintenance of cell shape
GT360_12610	COG1077	Cell shape determining protein MreB Mrl
GT360_12665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GT360_12675	COG3267	Type II secretory pathway component ExeA
GT360_12675	COG3409	Peptidoglycan-binding domain 1 protein
GT360_12700	COG2200	EAL domain
GT360_12700	COG2199	diguanylate cyclase activity
GT360_12705	COG0629	single-stranded DNA binding
GT360_12720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GT360_12730	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GT360_12735	COG0527	aspartate kinase activity
GT360_12800	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GT360_12820	COG0582	viral genome integration into host DNA
GT360_12855	COG0589	response to stress
GT360_12860	COG0735	belongs to the Fur family
GT360_12875	COG0432	Pfam Uncharacterised protein family UPF0047
GT360_12885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GT360_12910	COG2965	DNA replication, synthesis of RNA primer
GT360_12920	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GT360_12925	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GT360_12945	COG2923	Belongs to the DsrF TusC family
GT360_12950	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GT360_12955	COG2964	Protein conserved in bacteria
GT360_12960	COG0545	Peptidyl-prolyl cis-trans isomerase
GT360_12975	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GT360_12980	COG0330	HflC and HflK could
GT360_12985	COG0330	HflC and HflK could
GT360_12990	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GT360_13000	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GT360_13005	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GT360_13010	COG0860	N-Acetylmuramoyl-L-alanine amidase
GT360_13015	COG0802	atpase or kinase
GT360_13020	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GT360_13090	COG1162	GTPase activity
GT360_13095	COG0688	phosphatidylethanolamine metabolic process
GT360_13100	COG0471	metal ion transport
GT360_13100	COG0490	domain, Protein
GT360_13110	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GT360_13115	COG4942	peptidase
GT360_13130	COG2816	NAD+ diphosphatase activity
GT360_13135	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GT360_13145	COG0085	RNA polymerase activity
GT360_13150	COG0222	ribosome binding
GT360_13155	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GT360_13170	COG0250	Participates in transcription elongation, termination and antitermination
GT360_13175	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GT360_13180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GT360_13205	COG1072	(Pantothenic acid kinase))
GT360_13220	COG0149	triose-phosphate isomerase activity
GT360_13225	COG0534	Mate efflux family protein
GT360_13235	COG1575	Belongs to the MenA family. Type 1 subfamily
GT360_13240	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GT360_13245	COG1509	lysine 2,3-aminomutase activity
GT360_13250	COG1285	pathogenesis
GT360_13255	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GT360_13260	COG3383	formate dehydrogenase (NAD+) activity
GT360_13270	COG0546	phosphoglycolate phosphatase activity
GT360_13275	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GT360_13280	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GT360_13325	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GT360_13330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GT360_13395	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GT360_13405	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GT360_13425	COG1216	Glycosyl transferase, family 2
GT360_13435	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GT360_13465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GT360_13470	COG2895	sulfate adenylyltransferase (ATP) activity
GT360_13480	COG0529	Catalyzes the synthesis of activated sulfate
GT360_13490	COG0175	sulfate reduction
GT360_13495	COG3273	potassium ion transport
GT360_13495	COG0471	metal ion transport
GT360_13510	COG0438	transferase activity, transferring glycosyl groups
GT360_13510	COG1216	Glycosyl transferase, family 2
GT360_13530	COG0438	transferase activity, transferring glycosyl groups
GT360_13530	COG1216	Glycosyl transferase, family 2
GT360_13550	COG3023	N-Acetylmuramoyl-L-alanine amidase
GT360_13640	COG1560	Kdo2-lipid A biosynthetic process
GT360_13655	COG0859	PFAM glycosyl transferase family 9
GT360_13665	COG3642	lipopolysaccharide core region biosynthetic process
GT360_13675	COG1519	Transferase
GT360_13680	COG0859	PFAM glycosyl transferase family 9
GT360_13695	COG0438	transferase activity, transferring glycosyl groups
GT360_13700	COG3306	glycosyltransferase involved in LPS biosynthesis
GT360_13725	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GT360_13730	COG2205	protein histidine kinase activity
GT360_13735	COG0745	RESPONSE REGULATOR receiver
GT360_13740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GT360_13750	COG2183	response to ionizing radiation
GT360_13765	COG1040	competence protein
GT360_13770	COG0316	Belongs to the HesB IscA family
GT360_13770	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GT360_13775	COG1028	Short-chain dehydrogenase reductase Sdr
GT360_13780	COG0494	nUDIX hydrolase
GT360_13785	COG1218	3'(2'),5'-bisphosphate nucleotidase
GT360_13795	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GT360_13800	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GT360_13805	COG3156	type II secretion system protein K
GT360_13810	COG4795	General secretion pathway protein
GT360_13815	COG2165	general secretion pathway protein
GT360_13820	COG2165	general secretion pathway protein
GT360_13825	COG2165	general secretion pathway protein
GT360_13830	COG1459	type II secretion system
GT360_13835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GT360_13845	COG3031	protein transport across the cell outer membrane
GT360_13850	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GT360_13870	COG0456	acetyltransferase
GT360_13875	COG1490	D-aminoacyl-tRNA deacylase activity
GT360_13900	COG0174	glutamine synthetase
GT360_13910	COG3852	Histidine kinase
GT360_13915	COG2204	response regulator
GT360_13920	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GT360_13925	COG1360	Flagellar Motor Protein
GT360_13930	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GT360_13935	COG1191	sigma factor activity
GT360_13940	COG1580	Controls the rotational direction of flagella during chemotaxis
GT360_13960	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GT360_13970	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GT360_13985	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GT360_13990	COG1256	bacterial-type flagellum assembly
GT360_13990	COG4786	Flagellar basal body rod
GT360_14000	COG1706	bacterial-type flagellum-dependent cell motility
GT360_14005	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GT360_14010	COG4786	Flagellar basal body rod
GT360_14020	COG1749	Flagellar hook protein flgE
GT360_14030	COG1558	bacterial-type flagellum-dependent cell motility
GT360_14035	COG1815	bacterial-type flagellum-dependent cell motility
GT360_14080	COG1677	Flagellar hook-basal body complex protein FliE
GT360_14110	COG1987	bacterial-type flagellum assembly
GT360_14120	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GT360_14130	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GT360_14135	COG1053	succinate dehydrogenase
GT360_14140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GT360_14145	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GT360_14150	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GT360_14155	COG0583	DNA-binding transcription factor activity
GT360_14160	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GT360_14185	COG1609	Transcriptional regulator
GT360_14190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GT360_14200	COG0281	malic enzyme
GT360_14205	COG0515	serine threonine protein kinase
GT360_14205	COG2815	serine threonine protein kinase
GT360_14225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT360_14240	COG4172	Belongs to the ABC transporter superfamily
GT360_14275	COG0210	DNA helicase
GT360_14280	COG1309	transcriptional regulator
GT360_14285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT360_14290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT360_14295	COG2960	long-chain fatty acid transporting porin activity
GT360_14300	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GT360_14340	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GT360_14340	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GT360_14355	COG0084	hydrolase, TatD family'
GT360_14360	COG0805	protein transport
GT360_14365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GT360_14375	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GT360_14385	COG2226	methyltransferase
GT360_14390	COG1322	Protein conserved in bacteria
GT360_14405	COG2081	HI0933 family
GT360_14415	COG1528	Iron-storage protein
GT360_14420	COG0589	response to stress
GT360_14430	COG0742	ribosomal rna small subunit methyltransferase
GT360_14435	COG1522	sequence-specific DNA binding
GT360_14455	COG0006	proline dipeptidase activity
GT360_14455	COG0006	proline dipeptidase activity
GT360_14460	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GT360_14465	COG2022	thiamine diphosphate biosynthetic process
GT360_14475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GT360_14480	COG0352	thiamine-phosphate diphosphorylase activity
GT360_14490	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GT360_14495	COG0071	Belongs to the small heat shock protein (HSP20) family
GT360_14500	COG0187	DNA topoisomerase II activity
GT360_14515	COG0456	acetyltransferase
GT360_14535	COG1126	abc transporter atp-binding protein
GT360_14540	COG0765	amino acid transport
GT360_14550	COG0765	amino acid transport
GT360_14575	COG0789	Transcriptional regulator
GT360_14580	COG3012	SEC-C Motif Domain Protein
GT360_14585	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GT360_14595	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GT360_14600	COG0215	cysteine-tRNA ligase activity
GT360_14610	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GT360_14615	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GT360_14625	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GT360_14635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GT360_14645	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GT360_14650	COG0297	glycogen (starch) synthase activity
GT360_14655	COG2267	carboxylic ester hydrolase activity
GT360_14670	COG3070	regulator of competence-specific genes
GT360_14675	COG1609	Transcriptional regulator
GT360_14685	COG0745	RESPONSE REGULATOR receiver
GT360_14690	COG0450	alkyl hydroperoxide reductase
GT360_14710	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GT360_14715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GT360_14730	COG0189	ligase activity
GT360_14730	COG4067	protein conserved in archaea
GT360_14745	COG1686	Belongs to the peptidase S11 family
GT360_14750	COG1801	Protein of unknown function DUF72
GT360_14760	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GT360_14780	COG1609	Transcriptional regulator
GT360_14785	COG3842	ATPase activity
GT360_14790	COG1472	Belongs to the glycosyl hydrolase 3 family
GT360_14795	COG0786	glutamate:sodium symporter activity
GT360_14800	COG2115	Belongs to the xylose isomerase family
GT360_14805	COG4977	sequence-specific DNA binding
GT360_14815	COG4580	involved in the transport of maltose and maltodextrins
GT360_14820	COG3842	ATPase activity
GT360_14830	COG1175	transmembrane transport
GT360_14835	COG0395	ABC-type sugar transport system, permease component
GT360_14840	COG3693	PFAM glycoside hydrolase, family 10
GT360_14840	COG3507	Belongs to the glycosyl hydrolase 43 family
GT360_14840	COG2382	esterase
GT360_14855	COG1609	Transcriptional regulator
GT360_14865	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT360_14875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT360_14885	COG0189	ligase activity
GT360_14890	COG3085	chromosome segregation
GT360_14910	COG2115	Belongs to the xylose isomerase family
GT360_14915	COG2211	Major facilitator Superfamily
GT360_14920	COG2207	Transcriptional regulator
GT360_14925	COG1472	Belongs to the glycosyl hydrolase 3 family
GT360_14945	COG2814	Major facilitator Superfamily
GT360_14970	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT360_14975	COG0583	DNA-binding transcription factor activity
GT360_14985	COG4213	ABC transporter substrate-binding protein
GT360_14990	COG1129	ABC transporter
GT360_14995	COG4214	carbohydrate transport
GT360_15000	COG1609	Transcriptional regulator
GT360_15000	COG2207	Transcriptional regulator
GT360_15005	COG1070	Carbohydrate kinase
GT360_15015	COG1566	PFAM secretion protein HlyD family protein
GT360_15040	COG1028	Short-chain dehydrogenase reductase Sdr
GT360_15045	COG3507	Belongs to the glycosyl hydrolase 43 family
GT360_15050	COG1028	Short-chain dehydrogenase reductase Sdr
GT360_15060	COG0840	transmembrane signaling receptor activity
GT360_15075	COG1511	domain protein
GT360_15075	COG3264	Mechanosensitive ion channel
GT360_15095	COG1917	Cupin 2, conserved barrel domain protein
GT360_15100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT360_15105	COG0800	Aldolase
GT360_15115	COG3015	lipoprotein NlpE involved in copper resistance
GT360_15135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GT360_15135	COG4124	Belongs to the glycosyl hydrolase 26 family
GT360_15145	COG3122	Protein conserved in bacteria
GT360_15150	COG0454	-acetyltransferase
GT360_15195	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GT360_15200	COG4221	oxidoreductase activity
GT360_15210	COG1132	(ABC) transporter
GT360_15215	COG1132	(ABC) transporter
GT360_15225	COG0456	acetyltransferase
GT360_15235	COG2095	MarC family integral membrane protein
GT360_15245	COG3394	polysaccharide catabolic process
GT360_15250	COG1486	melibiose metabolic process
GT360_15255	COG0583	DNA-binding transcription factor activity
GT360_15260	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GT360_15265	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GT360_15275	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GT360_15280	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GT360_15300	COG1335	isochorismatase
GT360_15380	COG1136	(ABC) transporter
GT360_15410	COG0814	amino acid
GT360_15425	COG0583	DNA-binding transcription factor activity
GT360_15430	COG0702	epimerase
GT360_15440	COG0402	S-adenosylhomocysteine deaminase activity
GT360_15470	COG1733	regulation of RNA biosynthetic process
GT360_15475	COG0513	Belongs to the DEAD box helicase family
GT360_15510	COG0583	DNA-binding transcription factor activity
GT360_15520	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GT360_15565	COG3842	ATPase activity
GT360_15580	COG0439	Biotin carboxylase
GT360_15595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT360_15610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GT360_15615	COG1278	Cold shock
GT360_15625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GT360_15640	COG0300	oxidoreductase activity
GT360_15655	COG0604	alcohol dehydrogenase
GT360_15655	COG3321	synthase
GT360_15660	COG4667	esterase of the alpha-beta hydrolase superfamily
GT360_15665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GT360_15680	COG0789	Transcriptional regulator
GT360_15715	COG1011	Hydrolase
GT360_15735	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GT360_15765	COG2190	(PTS) system
GT360_15765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GT360_15765	COG1263	PTS System
GT360_15835	COG2866	Carboxypeptidase
GT360_15850	COG3706	GGDEF domain
GT360_15860	COG1335	isochorismatase
GT360_15895	COG1051	belongs to the nudix hydrolase family
GT360_15900	COG0302	gtp cyclohydrolase
GT360_15900	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GT360_15905	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GT360_15920	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GT360_15945	COG2154	pterin-4-alpha-carbinolamine dehydratase
GT360_15960	COG1609	Transcriptional regulator
GT360_15965	COG0366	Alpha amylase catalytic
GT360_15975	COG0667	Aldo Keto reductase
GT360_15990	COG0583	DNA-binding transcription factor activity
GT360_16015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GT360_16035	COG0641	radical SAM
GT360_16040	COG3119	arylsulfatase activity
GT360_16045	COG0583	DNA-binding transcription factor activity
GT360_16090	COG4221	oxidoreductase activity
GT360_16105	COG0628	permease
GT360_16125	COG1234	tRNA 3'-trailer cleavage
GT360_16135	COG2205	protein histidine kinase activity
GT360_16135	COG5002	protein histidine kinase activity
GT360_16135	COG0784	Response regulator, receiver
GT360_16155	COG0561	phosphatase activity
GT360_16165	COG2017	converts alpha-aldose to the beta-anomer
GT360_16175	COG0583	DNA-binding transcription factor activity
GT360_16180	COG0840	transmembrane signaling receptor activity
GT360_16185	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GT360_16195	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GT360_16205	COG4628	conserved protein (DUF2132)
GT360_16210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GT360_16235	COG0456	acetyltransferase
GT360_16240	COG1858	cytochrome C peroxidase
GT360_16245	COG2205	protein histidine kinase activity
GT360_16245	COG0784	Response regulator, receiver
GT360_16250	COG0784	Response regulator, receiver
GT360_16250	COG2205	protein histidine kinase activity
GT360_16275	COG0583	DNA-binding transcription factor activity
GT360_16300	COG3214	Protein conserved in bacteria
GT360_16305	COG2205	protein histidine kinase activity
GT360_16305	COG0784	Response regulator, receiver
GT360_16310	COG0346	lactoylglutathione lyase activity
GT360_16325	COG2017	converts alpha-aldose to the beta-anomer
GT360_16335	COG3321	synthase
GT360_16335	COG0604	alcohol dehydrogenase
GT360_16335	COG1028	Short-chain dehydrogenase reductase Sdr
GT360_16350	COG0446	pyridine nucleotide-disulphide oxidoreductase
GT360_16350	COG1902	pentaerythritol trinitrate reductase activity
GT360_16365	COG1115	amino acid carrier protein
GT360_16375	COG1760	l-serine dehydratase
GT360_16400	COG1609	Transcriptional regulator
GT360_16405	COG1067	ATP-dependent peptidase activity
GT360_16425	COG2116	formate transmembrane transporter activity
GT360_16430	COG4221	oxidoreductase activity
GT360_16440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT360_16445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GT360_16450	COG4521	taurine ABC transporter
GT360_16455	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GT360_16460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT360_16495	COG4251	negative regulation of phosphorylation
GT360_16495	COG5001	Diguanylate cyclase
GT360_16495	COG2203	Gaf domain
GT360_16495	COG3706	GGDEF domain
GT360_16520	COG2855	membrane
GT360_16525	COG0583	DNA-binding transcription factor activity
GT360_16535	COG0110	maltose O-acetyltransferase activity
GT360_16580	COG1132	(ABC) transporter
GT360_16585	COG2274	protein secretion by the type I secretion system
GT360_16595	COG0745	RESPONSE REGULATOR receiver
GT360_16615	COG2273	Hydrolase Family 16
GT360_16615	COG5297	Belongs to the glycosyl hydrolase family 6
GT360_16630	COG2200	EAL domain
GT360_16645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT360_16660	COG2814	Major facilitator Superfamily
GT360_16665	COG0583	DNA-binding transcription factor activity
GT360_16685	COG0243	molybdopterin cofactor binding
GT360_16690	COG0437	4 iron, 4 sulfur cluster binding
GT360_16695	COG3302	dmso reductase anchor subunit
GT360_16705	COG2221	Nitrite and sulphite reductase 4Fe-4S
GT360_16705	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GT360_16720	COG3300	MHYT domain
GT360_16720	COG5001	Diguanylate cyclase
GT360_16730	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GT360_16740	COG3706	GGDEF domain
GT360_16745	COG0415	Belongs to the DNA photolyase family
GT360_16750	COG3046	protein related to deoxyribodipyrimidine photolyase
GT360_16760	COG0784	Response regulator, receiver
GT360_16760	COG0835	chemotaxis
GT360_16765	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GT360_16770	COG0840	transmembrane signaling receptor activity
GT360_16785	COG4166	transmembrane transport
GT360_16790	COG4174	ABC transporter (Permease)
GT360_16795	COG4239	(ABC) transporter, permease
GT360_16800	COG4172	Belongs to the ABC transporter superfamily
GT360_16810	COG0789	Transcriptional regulator
GT360_16815	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GT360_16820	COG0739	heme binding
GT360_16830	COG1902	pentaerythritol trinitrate reductase activity
GT360_16835	COG0471	metal ion transport
GT360_16840	COG2814	Major facilitator Superfamily
GT360_16845	COG0534	Mate efflux family protein
GT360_16855	COG3119	arylsulfatase activity
GT360_16870	COG0714	Associated with various cellular activities
GT360_16890	COG2304	oxidoreductase activity
GT360_16900	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GT360_16910	COG2390	Transcriptional regulator
GT360_16915	COG2897	thiosulfate sulfurtransferase activity
GT360_16925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GT360_16935	COG0302	gtp cyclohydrolase
GT360_16940	COG0513	Belongs to the DEAD box helicase family
GT360_16945	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GT360_16950	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GT360_16955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GT360_16960	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GT360_16960	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GT360_16970	COG1979	alcohol dehydrogenase
GT360_16975	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GT360_17000	COG4149	molybdate abc transporter
GT360_17005	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GT360_17015	COG0745	RESPONSE REGULATOR receiver
GT360_17020	COG3706	GGDEF domain
GT360_17035	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GT360_17040	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GT360_17060	COG0745	RESPONSE REGULATOR receiver
GT360_17075	COG3140	Belongs to the UPF0181 family
GT360_17095	COG0023	Translation Initiation Factor
GT360_17115	COG0045	succinate-CoA ligase (ADP-forming) activity
GT360_17115	COG1042	CoA-binding domain protein
GT360_17115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GT360_17120	COG0583	DNA-binding transcription factor activity
GT360_17125	COG4533	DNA binding
GT360_17130	COG2050	protein possibly involved in aromatic compounds catabolism
GT360_17150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GT360_17155	COG3118	belongs to the thioredoxin family
GT360_17185	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GT360_17220	COG0545	Peptidyl-prolyl cis-trans isomerase
GT360_17225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT360_17240	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GT360_17245	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GT360_17250	COG1984	allophanate hydrolase subunit 2
GT360_17260	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GT360_17265	COG4181	ATPase activity
GT360_17275	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GT360_17280	COG3300	MHYT domain
GT360_17280	COG5001	Diguanylate cyclase
GT360_17290	COG0484	heat shock protein binding
GT360_17295	COG1324	tolerance protein
GT360_17310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT360_17340	COG0633	Ferredoxin
GT360_17340	COG3217	Mosc domain protein beta barrel domain protein
GT360_17365	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GT360_17370	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GT360_17380	COG0277	FAD linked oxidase domain protein
GT360_17385	COG0247	lactate metabolic process
GT360_17395	COG0714	Associated with various cellular activities
GT360_17415	COG2304	oxidoreductase activity
GT360_17440	COG1461	Dihydroxyacetone kinase
GT360_17445	COG2376	Dihydroxyacetone kinase
GT360_17470	COG0765	amino acid transport
GT360_17475	COG1126	abc transporter atp-binding protein
GT360_17480	COG1609	Transcriptional regulator
GT360_17490	COG0673	inositol 2-dehydrogenase activity
GT360_17495	COG1129	ABC transporter
GT360_17500	COG1172	Belongs to the binding-protein-dependent transport system permease family
GT360_17505	COG1879	ABC-type sugar transport system periplasmic component
GT360_17530	COG0848	biopolymer transport protein
GT360_17535	COG0811	peptide transport
GT360_17540	COG0811	peptide transport
GT360_17550	COG3437	response regulator, receiver
GT360_17555	COG0641	radical SAM
GT360_17560	COG2885	chlorophyll binding
GT360_17570	COG0534	Mate efflux family protein
GT360_17575	COG0784	Response regulator, receiver
GT360_17575	COG2205	protein histidine kinase activity
GT360_17575	COG5002	protein histidine kinase activity
GT360_17595	COG1733	regulation of RNA biosynthetic process
GT360_17610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GT360_17615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GT360_17620	COG1120	ATPase activity
GT360_17665	COG1268	BioY protein
GT360_17670	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GT360_17675	COG1122	ATPase activity
GT360_17680	COG2807	transmembrane transport
GT360_17690	COG2738	Putative neutral zinc metallopeptidase
GT360_17815	COG1074	ATP-dependent DNA helicase activity
GT360_17825	COG0681	Belongs to the peptidase S26 family
GT360_17905	COG1904	glucuronate isomerase
GT360_17910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT360_17930	COG1028	Short-chain dehydrogenase reductase Sdr
GT360_17950	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT360_17960	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GT360_17965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT360_17970	COG0800	Aldolase
GT360_17985	COG4656	Part of a membrane complex involved in electron transport
GT360_17990	COG1454	alcohol dehydrogenase
GT360_17995	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GT360_18005	COG1454	alcohol dehydrogenase
GT360_18030	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GT360_18045	COG1882	Formate acetyltransferase
GT360_18065	COG2211	Major facilitator Superfamily
GT360_18095	COG3119	arylsulfatase activity
GT360_18105	COG3507	Belongs to the glycosyl hydrolase 43 family
GT360_18110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT360_18125	COG1028	Short-chain dehydrogenase reductase Sdr
GT360_18130	COG1454	alcohol dehydrogenase
GT360_18145	COG2149	membrane
GT360_18155	COG0641	radical SAM
GT360_18165	COG3408	Glycogen debranching enzyme
GT360_18165	COG3119	arylsulfatase activity
GT360_18170	COG3254	rhamnose metabolic process
GT360_18175	COG0235	Class ii aldolase
GT360_18180	COG4806	L-rhamnose isomerase
GT360_18185	COG1070	Carbohydrate kinase
GT360_18190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT360_18195	COG4977	sequence-specific DNA binding
GT360_18195	COG1917	Cupin 2, conserved barrel domain protein
GT360_18225	COG3119	arylsulfatase activity
GT360_18235	COG3507	Belongs to the glycosyl hydrolase 43 family
GT360_18240	COG3408	Glycogen debranching enzyme
GT360_18245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT360_18250	COG3119	arylsulfatase activity
GT360_18255	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GT360_18290	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT360_18300	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GT360_18320	COG0582	viral genome integration into host DNA
GT360_18340	COG1063	alcohol dehydrogenase
GT360_18355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT360_18385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GT360_18395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT360_18410	COG0583	DNA-binding transcription factor activity
GT360_18440	COG0519	Catalyzes the synthesis of GMP from XMP
GT360_18450	COG1609	Transcriptional regulator
GT360_18455	COG1234	tRNA 3'-trailer cleavage
GT360_18480	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GT360_18485	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GT360_18490	COG3842	ATPase activity
GT360_18495	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GT360_18500	COG1175	transmembrane transport
GT360_18510	COG1609	Transcriptional regulator
GT360_18515	COG1653	transport
GT360_18525	COG0395	ABC-type sugar transport system, permease component
GT360_18530	COG3842	ATPase activity
GT360_18535	COG1349	DNA-binding transcription factor activity
GT360_18540	COG0584	glycerophosphoryl diester phosphodiesterase
GT360_18570	COG0725	ABC transporter, periplasmic molybdate-binding protein
GT360_18580	COG1396	sequence-specific DNA binding
GT360_18585	COG3135	benzoate transporter
GT360_18590	COG0798	PFAM Bile acid sodium symporter
GT360_18600	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GT360_18615	COG0039	L-malate dehydrogenase activity
GT360_18635	COG0673	inositol 2-dehydrogenase activity
GT360_18660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT360_18665	COG0673	inositol 2-dehydrogenase activity
GT360_18670	COG3962	Belongs to the TPP enzyme family
GT360_18680	COG0477	Major facilitator Superfamily
GT360_18680	COG2814	Major facilitator Superfamily
GT360_18700	COG0183	Belongs to the thiolase family
GT360_18705	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GT360_18725	COG1566	PFAM secretion protein HlyD family protein
GT360_18730	COG1538	Outer membrane efflux protein
GT360_18775	COG1269	ATP hydrolysis coupled proton transport
GT360_18795	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
GT360_18830	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GT360_18835	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GT360_18845	COG0583	DNA-binding transcription factor activity
GT360_18850	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GT360_18875	COG0784	Response regulator, receiver
GT360_18875	COG2205	protein histidine kinase activity
GT360_18885	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GT360_18890	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GT360_18895	COG2885	chlorophyll binding
GT360_18915	COG0811	peptide transport
GT360_18920	COG0824	Thioesterase
GT360_18930	COG4890	Cyd operon protein YbgT
GT360_18935	COG1294	oxidase, subunit
GT360_18940	COG1271	oxidase subunit
GT360_18945	COG2255	four-way junction helicase activity
GT360_18950	COG0632	four-way junction helicase activity
GT360_18955	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GT360_18960	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GT360_18960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GT360_18960	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GT360_18965	COG1105	Belongs to the carbohydrate kinase PfkB family
GT360_18970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT360_18970	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT360_18975	COG1609	Transcriptional regulator
GT360_18985	COG4771	TonB-dependent receptor
GT360_18995	COG4607	ABC-type enterochelin transport system periplasmic component
GT360_19000	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GT360_19005	COG4605	iron ion homeostasis
GT360_19010	COG4604	ABC transporter, ATP-binding protein
GT360_19035	COG2814	Major facilitator Superfamily
GT360_19060	COG2149	membrane
GT360_19080	COG0641	radical SAM
GT360_19085	COG1414	Transcriptional regulator
GT360_19095	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GT360_19100	COG0800	Aldolase
GT360_19105	COG3734	2-keto-3-deoxy-galactonokinase
GT360_19110	COG4948	Mandelate Racemase Muconate Lactonizing
GT360_19115	COG1012	belongs to the aldehyde dehydrogenase family
GT360_19145	COG3038	cytochrome b561
GT360_19160	COG0745	RESPONSE REGULATOR receiver
GT360_19165	COG3850	Histidine kinase
GT360_19165	COG5002	protein histidine kinase activity
GT360_19170	COG2706	6-phosphogluconolactonase activity
GT360_19180	COG4667	esterase of the alpha-beta hydrolase superfamily
GT360_19195	COG1597	lipid kinase activity
GT360_19205	COG4067	protein conserved in archaea
GT360_19205	COG0189	ligase activity
GT360_19215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GT360_19240	COG0437	4 iron, 4 sulfur cluster binding
GT360_19245	COG0243	molybdopterin cofactor binding
GT360_19245	COG3383	formate dehydrogenase (NAD+) activity
GT360_19275	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GT360_19285	COG0443	Heat shock 70 kDa protein
GT360_19315	COG0656	L-ascorbic acid biosynthetic process
GT360_19330	COG0659	secondary active sulfate transmembrane transporter activity
GT360_19360	COG0745	RESPONSE REGULATOR receiver
GT360_19395	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GT360_19400	COG0363	glucosamine-6-phosphate deaminase activity
GT360_19405	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GT360_19440	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GT360_19445	COG0786	glutamate:sodium symporter activity
GT360_19460	COG2985	domain, Protein
GT360_19485	COG2272	Belongs to the type-B carboxylesterase lipase family
GT360_19490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GT360_19495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GT360_19500	COG0729	surface antigen
GT360_19555	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GT360_19610	COG0583	DNA-binding transcription factor activity
GT360_19615	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GT360_19620	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GT360_19625	COG3639	organic phosphonate transmembrane transporter activity
GT360_19635	COG2186	Transcriptional regulator
GT360_19640	COG2186	Transcriptional regulator
GT360_19645	COG0517	IMP dehydrogenase activity
GT360_19650	COG2176	DNA-directed DNA polymerase activity
GT360_19665	COG3181	Tripartite tricarboxylate transporter family receptor
GT360_19695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT360_19705	COG1595	DNA-templated transcription, initiation
GT360_19720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GT360_19725	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GT360_19730	COG0653	protein targeting
GT360_19735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GT360_19770	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GT360_19775	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GT360_19785	COG0539	negative regulation of cytoplasmic translation
GT360_19795	COG1555	photosystem II stabilization
GT360_19800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GT360_19805	COG0776	regulation of translation
GT360_19810	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GT360_19825	COG0544	peptidyl-prolyl cis-trans isomerase activity
GT360_19840	COG0583	DNA-binding transcription factor activity
GT360_19895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GT360_19895	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GT360_19915	COG0419	ATPase involved in DNA repair
GT360_19925	COG0737	Belongs to the 5'-nucleotidase family
GT360_19930	COG3593	DNA synthesis involved in DNA repair
GT360_19935	COG2116	formate transmembrane transporter activity
GT360_19940	COG2353	YceI-like domain
GT360_19945	COG3038	cytochrome b561
GT360_19955	COG2197	response regulator
GT360_19960	COG3850	Histidine kinase
GT360_19965	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
GT360_19965	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GT360_19985	COG3005	denitrification pathway
GT360_20015	COG0183	Belongs to the thiolase family
GT360_20025	COG0733	neurotransmitter:sodium symporter activity
GT360_20045	COG0668	transmembrane transport
GT360_20055	COG2205	protein histidine kinase activity
GT360_20055	COG0784	Response regulator, receiver
GT360_20075	COG0628	permease
GT360_20085	COG1566	PFAM secretion protein HlyD family protein
GT360_20090	COG3852	Histidine kinase
GT360_20095	COG2204	response regulator
GT360_20105	COG4662	Binding-protein-dependent transport system inner membrane component
GT360_20110	COG3842	ATPase activity
GT360_20170	COG2894	cell division
GT360_20180	COG4964	Belongs to the GSP D family
GT360_20200	COG0513	Belongs to the DEAD box helicase family
GT360_20210	COG2198	Histidine kinase
GT360_20210	COG0784	Response regulator, receiver
GT360_20210	COG2205	protein histidine kinase activity
GT360_20215	COG1879	ABC-type sugar transport system periplasmic component
GT360_20220	COG1803	Methylglyoxal synthase
GT360_20225	COG0210	DNA helicase
GT360_20230	COG1289	transmembrane transporter activity
GT360_20235	COG0784	Response regulator, receiver
GT360_20235	COG5002	protein histidine kinase activity
GT360_20240	COG1879	ABC-type sugar transport system periplasmic component
GT360_20245	COG2827	Endonuclease containing a URI domain
GT360_20265	COG1288	antiporter activity
GT360_20280	COG5001	Diguanylate cyclase
GT360_20280	COG3300	MHYT domain
GT360_20290	COG3706	GGDEF domain
GT360_20320	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GT360_20330	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GT360_20340	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GT360_20355	COG3530	Putative quorum-sensing-regulated virulence factor
GT360_20360	COG0513	Belongs to the DEAD box helicase family
GT360_20365	COG1686	Belongs to the peptidase S11 family
GT360_20370	COG1278	Cold shock
GT360_20390	COG4989	oxidoreductase activity
GT360_20400	COG2067	long-chain fatty acid transport protein
GT360_20405	COG2267	carboxylic ester hydrolase activity
GT360_20410	COG0739	heme binding
GT360_20435	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GT360_20440	COG0581	inorganic phosphate transmembrane transporter activity
GT360_20445	COG0573	inorganic phosphate transmembrane transporter activity
GT360_20455	COG0513	Belongs to the DEAD box helicase family
GT360_20465	COG1388	LysM domain
GT360_20465	COG1376	ErfK ybiS ycfS ynhG family protein
GT360_20470	COG0415	Belongs to the DNA photolyase family
GT360_20475	COG0789	Transcriptional regulator
GT360_20480	COG3272	Protein of unknown function (DUF1722)
GT360_20490	COG1566	PFAM secretion protein HlyD family protein
GT360_20510	COG1999	signal sequence binding
GT360_20540	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT360_20585	COG0583	DNA-binding transcription factor activity
GT360_20590	COG1620	l-lactate permease
GT360_20615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GT360_20620	COG1151	hydroxylamine reductase activity
GT360_20625	COG3604	Transcriptional regulator
GT360_20640	COG0783	Belongs to the Dps family
GT360_20645	COG0534	Mate efflux family protein
GT360_20650	COG2188	Transcriptional regulator
GT360_20660	COG1263	PTS System
GT360_20660	COG2190	(PTS) system
GT360_20660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GT360_20675	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GT360_20690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT360_20695	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GT360_20700	COG1640	4-alpha-glucanotransferase
GT360_20705	COG0058	SHG alpha-glucan phosphorylase activity
GT360_20710	COG2909	trisaccharide binding
GT360_20715	COG1902	pentaerythritol trinitrate reductase activity
GT360_20720	COG2084	Dehydrogenase
GT360_20725	COG0217	transcriptional regulatory protein
GT360_20770	COG1444	tRNA N-acetyltransferase activity
GT360_20785	COG1132	(ABC) transporter
GT360_20805	COG0583	DNA-binding transcription factor activity
GT360_20815	COG3706	GGDEF domain
GT360_20825	COG4580	involved in the transport of maltose and maltodextrins
GT360_20835	COG0366	Alpha amylase catalytic
GT360_20840	COG0366	Alpha amylase catalytic
GT360_20845	COG0534	Mate efflux family protein
GT360_20855	COG2249	NAD(P)H dehydrogenase (quinone) activity
GT360_20875	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GT360_20885	COG1301	dicarboxylic acid transport
GT360_20915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT360_20920	COG0564	pseudouridine synthase activity
GT360_20925	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GT360_20930	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GT360_20940	COG0402	S-adenosylhomocysteine deaminase activity
GT360_20945	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GT360_20955	COG0673	inositol 2-dehydrogenase activity
GT360_20960	COG1765	OsmC-like protein
GT360_21000	COG0179	Fumarylacetoacetate (FAA) hydrolase
GT360_21005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GT360_21010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GT360_21055	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GT360_21060	COG0668	transmembrane transport
GT360_21065	COG3123	guanosine phosphorylase activity
GT360_21095	COG3842	ATPase activity
GT360_21105	COG1175	transmembrane transport
GT360_21110	COG3833	ABC-type maltose transport systems, permease component
GT360_21130	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GT360_21140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GT360_21145	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GT360_21150	COG0513	Belongs to the DEAD box helicase family
GT360_21180	COG1840	ABC-type Fe3 transport system, periplasmic component
GT360_21185	COG3842	ATPase activity
GT360_21230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GT360_21235	COG2146	nitrite reductase [NAD(P)H] activity
GT360_21280	COG0582	viral genome integration into host DNA
GT360_21345	COG0724	RNA recognition motif
GT360_21360	COG0384	phenazine biosynthesis protein PhzF
GT360_21365	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GT360_21385	COG0625	glutathione transferase activity
GT360_21390	COG1742	UPF0060 membrane protein
GT360_21400	COG1011	Hydrolase
GT360_21405	COG4628	conserved protein (DUF2132)
GT360_21420	COG0037	tRNA processing
GT360_21420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GT360_21440	COG2824	Alkylphosphonate utilization operon protein PhnA
GT360_21450	COG2226	methyltransferase
GT360_21465	COG1454	alcohol dehydrogenase
GT360_21475	COG1328	CTP reductase activity
GT360_21480	COG0602	queuosine metabolic process
GT360_21515	COG1028	Short-chain dehydrogenase reductase Sdr
GT360_21535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT360_21540	COG1904	glucuronate isomerase
GT360_21550	COG1028	Short-chain dehydrogenase reductase Sdr
GT360_21570	COG0840	transmembrane signaling receptor activity
GT360_21585	COG1024	Enoyl-CoA hydratase
GT360_21590	COG0583	DNA-binding transcription factor activity
GT360_21605	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GT360_21615	COG2076	Multidrug Resistance protein
GT360_21635	COG2239	Acts as a magnesium transporter
GT360_21650	COG1278	Cold shock
GT360_21655	COG0583	DNA-binding transcription factor activity
GT360_21675	COG0509	glycine decarboxylation via glycine cleavage system
GT360_21685	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GT360_21695	COG0251	oxidation-reduction process
GT360_21715	COG0641	radical SAM
GT360_21755	COG0714	Associated with various cellular activities
GT360_21760	COG3119	arylsulfatase activity
GT360_21790	COG0714	Associated with various cellular activities
GT360_21795	COG3119	arylsulfatase activity
GT360_21800	COG4585	Histidine kinase
GT360_21805	COG2197	response regulator
GT360_21810	COG0641	radical SAM
GT360_21815	COG0753	catalase activity