locus-tag	class	description
A6E01_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
A6E01_00010	ENOG4105EAB	amino acid AbC transporter
A6E01_00015	ENOG4105E5Q	amino acid AbC transporter
A6E01_00020	ENOG4105CDA	abc transporter atp-binding protein
A6E01_00025	ENOG4105VG0	50S ribosomal protein l34
A6E01_00030	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
A6E01_00035	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
A6E01_00040	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
A6E01_00045	ENOG4105QTB	Flavodoxin
A6E01_00050	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
A6E01_00055	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
A6E01_00060	ENOG4107QJE	Chromosome Partitioning Protein
A6E01_00065	ENOG4105FA0	parb-like partition protein
A6E01_00070	ENOG410684E	atp synthase
A6E01_00075	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
A6E01_00080	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A6E01_00090	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A6E01_00095	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A6E01_00100	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A6E01_00110	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A6E01_00120	ENOG4105EAD	ABC transporter
A6E01_00125	ENOG4105F87	Dehydratase
A6E01_00130	ENOG4105CZQ	inner membrane transport protein YdhC
A6E01_00135	ENOG4105F52	Transcriptional regulator
A6E01_00140	ENOG4105C7B	Threonine dehydratase
A6E01_00145	ENOG4105C01	Dihydroxy-acid dehydratase
A6E01_00150	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A6E01_00155	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
A6E01_00165	ENOG4105C0P	Mg chelatase subunit ChlI
A6E01_00170	ENOG4106HNH	Acyl-transferase
A6E01_00175	ENOG4108Z33	Thiol disulfide Interchange Protein
A6E01_00180	ENOG4105E27	serine threonine protein kinase
A6E01_00190	ENOG4105PC1	Conserved Protein
A6E01_00195	ENOG4108N23	SpoOM-related protein
A6E01_00200	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
A6E01_00205	ENOG4105C1A	potassium transporter peripheral membrane
A6E01_00210	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A6E01_00215	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
A6E01_00220	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A6E01_00225	ENOG4105C79	DNA protecting protein DprA
A6E01_00230	ENOG4108RPN	Protein smg homolog
A6E01_00235	ENOG4108WI1	Dna topoisomerase
A6E01_00240	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
A6E01_00245	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A6E01_00250	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A6E01_00255	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
A6E01_00260	ENOG4105E2X	shikimate dehydrogenase
A6E01_00270	ENOG4108Z0R	Transferase
A6E01_00315	ENOG410601J	HemY protein
A6E01_00320	ENOG4105ECF	c-methyltransferase
A6E01_00330	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
A6E01_00340	ENOG4105XQ6	frataxin-like protein
A6E01_00345	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
A6E01_00350	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
A6E01_00360	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A6E01_00365	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
A6E01_00370	ENOG4106IUH	DTW domain containing protein
A6E01_00380	ENOG4105DQF	Hydrolase
A6E01_00385	ENOG4108EUD	Lysophospholipase
A6E01_00390	ENOG410829K	Lysine exporter protein (Lyse ygga)
A6E01_00395	ENOG41082YX	Transcriptional regulator, arsr family
A6E01_00400	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
A6E01_00440	ENOG4105DEF	Extracellular solute-binding protein, family 5
A6E01_00445	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A6E01_00450	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A6E01_00460	ENOG4105DC8	reductase
A6E01_00465	ENOG4105D6S	protein involved in catabolism of external DNA
A6E01_00470	ENOG4105DGW	oligopeptidase A
A6E01_00475	ENOG4108VVK	transcriptional Regulator, AsnC
A6E01_00480	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
A6E01_00490	ENOG4108M6U	Universal stress protein A
A6E01_00495	ENOG41090A1	ferritin
A6E01_00500	ENOG4108V6B	universal stress protein B
A6E01_00505	ENOG4105CBX	hi0933 family
A6E01_00530	ENOG4108JQ7	(ABC) transporter
A6E01_00565	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A6E01_00575	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
A6E01_00580	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
A6E01_00585	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
A6E01_00590	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
A6E01_00595	ENOG4105F8V	Hydrolase, tatD family
A6E01_00600	ENOG4105D52	delta-aminolevulinic acid dehydratase
A6E01_00610	ENOG4105C2M	dna polymerase I
A6E01_00615	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
A6E01_00635	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
A6E01_00645	ENOG4105D4P	Coproporphyrinogen iii oxidase
A6E01_00650	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6E01_00655	ENOG4105CUX	Signal transduction histidine kinase
A6E01_00660	ENOG4105C5F	glutamine synthetase
A6E01_00665	ENOG4105CI3	gtp-binding protein typa
A6E01_00675	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
A6E01_00680	ENOG4105SUU	thioesterase domain
A6E01_00690	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
A6E01_00695	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
A6E01_00700	ENOG4105VEJ	Heat shock protein
A6E01_00705	ENOG4108XKW	General secretion pathway protein C
A6E01_00715	ENOG4107QHF	type ii secretion system protein e
A6E01_00720	ENOG4105D7Q	type ii secretion system
A6E01_00725	ENOG4108VAU	general secretion pathway protein G
A6E01_00730	ENOG4105VWV	general secretion pathway protein h
A6E01_00735	ENOG4105X5Z	General secretion pathway protein I
A6E01_00740	ENOG4108WWZ	General secretion pathway protein J
A6E01_00745	ENOG4108RTD	type II secretion system protein K
A6E01_00750	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
A6E01_00755	ENOG4105U1E	general secretion pathway protein M
A6E01_00760	ENOG4105PIC	general secretion pathway protein N
A6E01_00765	ENOG4107RK2	ADP-ribose diphosphatase NudE
A6E01_00770	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
A6E01_00775	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
A6E01_00780	ENOG4105MJ2	Competence protein
A6E01_00785	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
A6E01_00790	ENOG4105E0F	Histidine kinase
A6E01_00795	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A6E01_00800	ENOG4108RRZ	Transcription elongation factor GreB
A6E01_00805	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A6E01_00810	ENOG4105BZM	domain protein
A6E01_00815	ENOG4105CB5	ATP-dependent DNA helicase recG
A6E01_00820	ENOG4105KDC	50s ribosomal protein l28
A6E01_00825	ENOG4105W0E	50S ribosomal protein L33
A6E01_00830	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
A6E01_00845	ENOG4107STW	synthase
A6E01_00850	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
A6E01_00855	ENOG4105DKP	glycosyl transferase, family 9
A6E01_00860	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
A6E01_00865	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
A6E01_00875	ENOG4105CPK	Glycosyl transferase (Group 1
A6E01_00890	ENOG4105C5E	polysaccharide biosynthesis protein
A6E01_00895	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A6E01_00900	ENOG4105F0R	Cytidylyltransferase
A6E01_00915	ENOG4107T8Q	Glycosyl transferase (Group 1
A6E01_00920	ENOG4107YYJ	Glycosyl transferase, family 2
A6E01_00925	ENOG4105XA0	heptosyltransferase ii
A6E01_00930	ENOG41068PG	O-Antigen polymerase
A6E01_00935	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
A6E01_00940	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
A6E01_00945	ENOG4108KPN	Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12)
A6E01_00955	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
A6E01_00960	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
A6E01_00970	ENOG4105ETE	Transcriptional regulator (LacI family
A6E01_00975	ENOG4105C25	Primosomal protein n'
A6E01_00980	ENOG4105VFB	Binds the 23S rRNA (By similarity)
A6E01_00985	ENOG4105C6K	Malic enzyme
A6E01_00990	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
A6E01_00995	ENOG4105C28	cystathionine
A6E01_01000	ENOG4105CFH	Aspartokinase
A6E01_01005	ENOG4105SYT	Methylenetetrahydrofolate reductase
A6E01_01010	ENOG4105U3E	Transcriptional regulator
A6E01_01015	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
A6E01_01020	ENOG4105CWC	Acetylornithine deacetylase
A6E01_01025	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
A6E01_01030	ENOG4105CAS	nag kinase
A6E01_01035	ENOG4105CDH	Citrulline--aspartate ligase
A6E01_01040	ENOG4105CH7	arginosuccinase
A6E01_01050	ENOG4107QN2	dihydrolipoyl dehydrogenase
A6E01_01055	ENOG4105EHV	domain protein
A6E01_01060	ENOG4105C5Q	Transcriptional regulator
A6E01_01065	ENOG4108JQC	penicillin-binding protein 1A
A6E01_01085	ENOG4105E4G	Type IV pilus
A6E01_01090	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A6E01_01095	ENOG4105D49	3-dehydroquinate synthase
A6E01_01105	ENOG4105DFE	Dna adenine methylase
A6E01_01110	ENOG4105DJV	ribulose-phosphate 3-epimerase
A6E01_01120	ENOG4105C31	Tryptophanyl-tRNA synthetase
A6E01_01125	ENOG4105DDQ	anthranilate synthase
A6E01_01130	ENOG4105C8Y	Acetylornithine aminotransferase
A6E01_01135	ENOG4105F4X	arginine
A6E01_01140	ENOG4105C26	Dehydrogenase
A6E01_01155	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
A6E01_01165	ENOG4105DNZ	Alpha Beta Hydrolase
A6E01_01175	ENOG4105C5H	ABC transporter
A6E01_01180	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
A6E01_01195	ENOG4108YZY	peptidylprolyl cis-trans isomerase
A6E01_01200	ENOG4105D44	asparaginase
A6E01_01205	ENOG41069P5	Protein slyX homolog
A6E01_01210	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A6E01_01215	ENOG4105WWK	YheO domain protein
A6E01_01220	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
A6E01_01225	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
A6E01_01235	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
A6E01_01240	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A6E01_01250	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A6E01_01255	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A6E01_01260	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A6E01_01265	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
A6E01_01270	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A6E01_01275	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A6E01_01280	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A6E01_01285	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
A6E01_01290	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A6E01_01295	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
A6E01_01300	ENOG41083MP	50s ribosomal protein l29
A6E01_01305	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A6E01_01310	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A6E01_01315	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
A6E01_01320	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A6E01_01330	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A6E01_01335	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A6E01_01345	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A6E01_01350	ENOG4105VPB	50S ribosomal protein L30
A6E01_01355	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A6E01_01360	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
A6E01_01370	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A6E01_01375	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A6E01_01380	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A6E01_01385	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A6E01_01390	ENOG4108ZT0	50S ribosomal protein l17
A6E01_01405	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A6E01_01410	ENOG4108UBT	opacity-associated protein
A6E01_01420	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A6E01_01445	ENOG4108UUE	Transcriptional regulator
A6E01_01450	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
A6E01_01455	ENOG4105CFU	surface antigen
A6E01_01465	ENOG41066HZ	AIG2-like family
A6E01_01470	ENOG4105QNF	Outer membrane lipoprotein
A6E01_01475	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
A6E01_01480	ENOG4105DFU	Cell wall formation (By similarity)
A6E01_01485	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A6E01_01490	ENOG4108IAB	Phoh family
A6E01_01495	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
A6E01_01500	ENOG4105D3G	Pseudouridine synthase
A6E01_01505	ENOG4105C5I	Dehydrogenase
A6E01_01510	ENOG41081QV	Universal stress protein
A6E01_01525	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
A6E01_01530	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
A6E01_01540	ENOG4105EAH	synthase
A6E01_01545	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
A6E01_01550	ENOG4105K46	50S ribosomal protein l27
A6E01_01555	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A6E01_01560	ENOG4105DR8	Membrane
A6E01_01565	ENOG4107XM3	UPF0442 protein
A6E01_01570	ENOG4107XM3	UPF0442 protein
A6E01_01580	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
A6E01_01585	ENOG4105NWN	ApaG protein
A6E01_01590	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A6E01_01595	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
A6E01_01600	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
A6E01_01605	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
A6E01_01610	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
A6E01_01625	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A6E01_01635	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A6E01_01670	ENOG41064T2	transcriptional regulator, lysR family
A6E01_01675	ENOG4108IQE	Amp-dependent synthetase and ligase
A6E01_01680	ENOG4105C7K	acetolactate synthase
A6E01_01685	ENOG4108ZP8	Acetolactate synthase small subunit
A6E01_01690	ENOG4105CA9	Pyruvate kinase
A6E01_01695	ENOG4105EE0	oxidoreductase
A6E01_01710	ENOG4105EUZ	Beta-lactamase domain protein
A6E01_01730	ENOG4105C3S	Mate efflux family protein
A6E01_01755	ENOG4105TMB	Formate nitrite transporter
A6E01_01760	ENOG4105DIQ	Transcriptional regulator
A6E01_01765	ENOG4105C01	Dihydroxy-acid dehydratase
A6E01_01770	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
A6E01_01775	ENOG4105C6Z	Gluconate
A6E01_01780	ENOG4108UHU	Aldolase
A6E01_01785	ENOG4105F27	Major Facilitator
A6E01_01790	ENOG4105EJC	lysr family transcriptional regulator
A6E01_01795	ENOG4108IJ7	Glycine betaine
A6E01_01800	ENOG4108HQS	Glycine betaine
A6E01_01835	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A6E01_01840	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A6E01_01845	ENOG4105KTH	gatB Yqey
A6E01_01850	ENOG4105VCC	30S ribosomal protein S21
A6E01_01855	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A6E01_01865	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
A6E01_01870	ENOG4107ZVW	dihydroneopterin aldolase
A6E01_01875	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A6E01_01880	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
A6E01_01885	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
A6E01_01900	ENOG4106MWK	domain protein
A6E01_01905	ENOG4105CJ3	phosphate transporter
A6E01_01910	ENOG4107IX6	phosphate transport regulator
A6E01_01915	ENOG4105I7R	Adenylate cyclase
A6E01_01920	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
A6E01_01925	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A6E01_01930	ENOG4105DFG	type I secretion outer membrane protein
A6E01_01935	ENOG41087AY	ADP-Ribose pyrophosphatase
A6E01_01940	ENOG4108SX3	cytoplasmic protein
A6E01_01945	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
A6E01_01950	ENOG4105IPS	esterase
A6E01_01955	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A6E01_01960	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A6E01_01965	ENOG4105C0H	protease
A6E01_01970	ENOG4105C0H	protease
A6E01_01980	ENOG4105D6Z	AFG1 family ATPase
A6E01_01985	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A6E01_01990	ENOG4108UJD	30S ribosomal protein S9
A6E01_01995	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
A6E01_02000	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
A6E01_02005	ENOG4105EIX	cytochrome c1
A6E01_02010	ENOG4107MKT	Stringent starvation protein a
A6E01_02015	ENOG4105KB2	stringent starvation protein b
A6E01_02020	ENOG4105W4M	Transport-associated protein
A6E01_02025	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
A6E01_02030	ENOG41082RQ	UPF0102 protein
A6E01_02035	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
A6E01_02040	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
A6E01_02050	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
A6E01_02055	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
A6E01_02060	ENOG4105CJN	penicillin-binding protein
A6E01_02065	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
A6E01_02070	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
A6E01_02080	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
A6E01_02090	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
A6E01_02095	ENOG4105DFU	Cell wall formation (By similarity)
A6E01_02100	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
A6E01_02105	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
A6E01_02110	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A6E01_02115	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A6E01_02125	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A6E01_02130	ENOG4105M6F	mutator MutT protein
A6E01_02135	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
A6E01_02145	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
A6E01_02150	ENOG4105EJ9	Membrane
A6E01_02155	ENOG4105VP0	transcriptional regulator, lysR family
A6E01_02160	ENOG4105EN6	Membrane
A6E01_02165	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
A6E01_02175	ENOG4105BZ8	glutamate synthase
A6E01_02180	ENOG4105CBC	glutamate synthase
A6E01_02195	ENOG4105N5T	Radical SAM Protein
A6E01_02200	ENOG4105BZU	Histidine kinase
A6E01_02210	ENOG41065U4	response regulator
A6E01_02225	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
A6E01_02230	ENOG4105D98	threonine synthase
A6E01_02235	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
A6E01_02240	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
A6E01_02245	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
A6E01_02260	ENOG4105BZG	amino acid carrier protein
A6E01_02265	ENOG4105D1Q	UPF0246 protein
A6E01_02270	ENOG4108YYQ	gCN5-related N-acetyltransferase
A6E01_02280	ENOG4105C1J	atp-dependent rna helicase
A6E01_02285	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
A6E01_02290	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
A6E01_02295	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
A6E01_02300	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A6E01_02305	ENOG4105T95	Thiol disulfide interChange protein
A6E01_02310	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
A6E01_02315	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
A6E01_02320	ENOG4105CRK	lysyL-tRNA synthetase
A6E01_02325	ENOG4105W87	Cbs domain
A6E01_02335	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
A6E01_02340	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
A6E01_02345	ENOG4105VIE	preprotein translocase, subunit YajC
A6E01_02350	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A6E01_02355	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A6E01_02360	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
A6E01_02365	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
A6E01_02380	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A6E01_02385	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
A6E01_02390	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
A6E01_02395	ENOG4108NEV	two component transcriptional regulator, LytTR family
A6E01_02400	ENOG4108HRK	Histidine kinase
A6E01_02405	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A6E01_02415	ENOG4105C5H	ABC transporter
A6E01_02420	ENOG4107SC1	transglycosylase
A6E01_02425	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
A6E01_02430	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A6E01_02440	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
A6E01_02445	ENOG4105E4C	Lytic transglycosylase catalytic
A6E01_02450	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A6E01_02455	ENOG4105C34	Pseudouridine synthase
A6E01_02460	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
A6E01_02465	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A6E01_02510	ENOG4105EMK	carboxylate amino acid amine transporter
A6E01_02520	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
A6E01_02525	ENOG4105CFP	Peptidase U32
A6E01_02535	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A6E01_02540	ENOG4105BZU	Histidine kinase
A6E01_02550	ENOG4105C9X	ppx gppa phosphatase
A6E01_02555	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
A6E01_02560	ENOG4105C8U	phosphate abc transporter
A6E01_02565	ENOG4105C8U	phosphate abc transporter
A6E01_02570	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A6E01_02580	ENOG4106N3A	copper homeostasis protein cutc
A6E01_02585	ENOG4105D3R	alkyl hydroperoxide reductase
A6E01_02590	ENOG4105C5Q	Transcriptional regulator
A6E01_02600	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
A6E01_02605	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
A6E01_02610	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
A6E01_02615	ENOG4105HF0	Membrane
A6E01_02620	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
A6E01_02625	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
A6E01_02640	ENOG41063Z6	transcriptional regulator, lysR family
A6E01_02645	ENOG41080HT	Transcriptional regulator, arsr family
A6E01_02650	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
A6E01_02655	ENOG4105CJR	Integral membrane protein (MviN
A6E01_02660	ENOG4105DTN	riboflavin biosynthesis protein ribF
A6E01_02665	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A6E01_02670	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
A6E01_02690	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
A6E01_02695	ENOG4105CHV	Transcription elongation factor NusA
A6E01_02700	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A6E01_02705	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
A6E01_02710	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A6E01_02715	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A6E01_02720	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A6E01_02740	ENOG4105ETE	Transcriptional regulator (LacI family
A6E01_02745	ENOG4106RZ4	Peptidase U32
A6E01_02750	ENOG4105CFP	Peptidase U32
A6E01_02755	ENOG4105XPQ	lipid carrier protein
A6E01_02760	ENOG4108YYD	acetyltransferase
A6E01_02770	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
A6E01_02775	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
A6E01_02780	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
A6E01_02785	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
A6E01_02790	ENOG4105EYA	deoxyribonuclease
A6E01_02795	ENOG4105D9N	nucleoside
A6E01_02805	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
A6E01_02810	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
A6E01_02820	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
A6E01_02830	ENOG4105EAC	phosphoserine phosphatase
A6E01_02835	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
A6E01_02840	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A6E01_02845	ENOG4108IQE	Amp-dependent synthetase and ligase
A6E01_02850	ENOG410600T	transposase
A6E01_02875	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
A6E01_02960	ENOG4105CNT	hydrolase family 2
A6E01_02975	ENOG4105UQX	Mate efflux family protein
A6E01_02985	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
A6E01_02995	ENOG4105DRS	transport system, permease
A6E01_03005	ENOG41060NJ	transcriptional regulator
A6E01_03010	ENOG4105CK2	sodium dicarboxylate symporter
A6E01_03015	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
A6E01_03020	ENOG4105X2V	dna damage-inducible protein
A6E01_03025	ENOG4105DUM	transcriptional regulator, lysR family
A6E01_03035	ENOG4105DSY	exodeoxyribonuclease V, gamma
A6E01_03040	ENOG4107QKA	exodeoxyribonuclease V beta
A6E01_03045	ENOG4107QYX	exodeoxyribonuclease v alpha
A6E01_03050	ENOG4107QZM	n-acetylglutamate synthase
A6E01_03055	ENOG4105CA3	membrane-bound lytic murein transglycosylase
A6E01_03060	ENOG4105CUZ	uba thif-type nad fad binding protein
A6E01_03065	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
A6E01_03070	ENOG4105C9B	Cysteine desulfurase
A6E01_03075	ENOG4107S0N	DJ-1 family
A6E01_03080	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A6E01_03085	ENOG4105DRB	nucleoside-specific channel-forming protein
A6E01_03105	ENOG4105K6V	RNA polymerase
A6E01_03120	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A6E01_03130	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
A6E01_03135	ENOG4105M85	Bola protein
A6E01_03140	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A6E01_03145	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A6E01_03150	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A6E01_03155	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A6E01_03160	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A6E01_03165	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
A6E01_03170	ENOG4105CJ2	(LipO)protein
A6E01_03180	ENOG4105C2W	permease
A6E01_03185	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A6E01_03195	ENOG4105VEQ	Cold shock protein
A6E01_03205	ENOG4105W1I	UPF0253 protein
A6E01_03210	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A6E01_03215	ENOG4108R96	Methyltransferase, YaeB family
A6E01_03220	ENOG4105CFC	Transporter
A6E01_03225	ENOG4105D01	(LipO)protein
A6E01_03230	ENOG4108UMI	ABC transporter, permease
A6E01_03240	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
A6E01_03245	ENOG4107AYK	membrAne
A6E01_03250	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A6E01_03255	ENOG4108VKG	metal-dependent hydrolase
A6E01_03265	ENOG4105EQR	Transposase IS116 IS110 IS902
A6E01_03270	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A6E01_03275	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
A6E01_03280	ENOG4108Z43	UPF0250 protein
A6E01_03285	ENOG4105DZ1	carboxypeptidase
A6E01_03290	ENOG4105K6T	rare lipoprotein A
A6E01_03295	ENOG4105CNI	cell division protein FtsW
A6E01_03300	ENOG4105CJN	penicillin-binding protein
A6E01_03305	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
A6E01_03310	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
A6E01_03315	ENOG4105DJF	DNA polymerase III, delta' subunit
A6E01_03320	ENOG4108U2H	Rare lipoprotein B
A6E01_03325	ENOG4105C8T	Leucyl-tRNA synthetase
A6E01_03330	ENOG4107PAI	alpha helical protein
A6E01_03340	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
A6E01_03345	ENOG4108JU5	Magnesium and cobalt efflux protein
A6E01_03355	ENOG4105C9A	Phoh family
A6E01_03360	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A6E01_03365	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
A6E01_03445	ENOG4105C3G	gtp-binding protein
A6E01_03450	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
A6E01_03455	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A6E01_03460	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
A6E01_03470	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
A6E01_03475	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
A6E01_03480	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A6E01_03490	ENOG41063JG	Transcriptional regulator
A6E01_03495	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
A6E01_03500	ENOG4105CGH	5'-nucleotidase
A6E01_03505	ENOG4108Z66	YbaK ebsC protein
A6E01_03515	ENOG4105EW9	transcriptional regulator AsnC family
A6E01_03520	ENOG4105FE9	pseudouridine synthase
A6E01_03525	ENOG4108DG9	Smr protein MutS2
A6E01_03560	ENOG41086KC	Transcriptional regulator
A6E01_03580	ENOG4105CMR	udp-glucose 4-epimerase
A6E01_03585	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
A6E01_03590	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A6E01_03600	ENOG4105ETE	Transcriptional regulator (LacI family
A6E01_03610	ENOG4107RUZ	Sss sodium solute transporter superfamily
A6E01_03615	ENOG4105E2D	ec 3.2.1.52
A6E01_03620	ENOG41081QG	Porin Gram-negative type
A6E01_03645	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
A6E01_03650	ENOG4105BZU	Histidine kinase
A6E01_03655	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A6E01_03660	ENOG4105BZU	Histidine kinase
A6E01_03665	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A6E01_03670	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A6E01_03675	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
A6E01_03680	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A6E01_03685	ENOG4105K70	DNA-binding protein
A6E01_03690	ENOG4105EIN	peptidylprolyl cis-trans isomerase
A6E01_03710	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
A6E01_03715	ENOG4105DK2	UPF0207 protein
A6E01_03720	ENOG4105CHM	Aminotransferase
A6E01_03725	ENOG4105E4F	Isochorismate synthase
A6E01_03735	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
A6E01_03740	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
A6E01_03745	ENOG4105CEY	Amp-dependent synthetase and ligase
A6E01_03770	ENOG4108DNC	Involved in acetate metabolism (By similarity)
A6E01_03775	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
A6E01_03780	ENOG4105PQ6	UPF0208 membrane protein
A6E01_03790	ENOG4105C7J	ABC transporter, permease
A6E01_03795	ENOG4108JJB	ABC transporter
A6E01_03800	ENOG4107R28	alpha amylase, catalytic region
A6E01_03805	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
A6E01_03810	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A6E01_03815	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
A6E01_03825	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
A6E01_03840	ENOG4105C0B	DNA polymerase III (alpha subunit)
A6E01_03865	ENOG4105BZU	Histidine kinase
A6E01_03870	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
A6E01_03875	ENOG4105C9B	Cysteine desulfurase
A6E01_03885	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
A6E01_03890	ENOG4105DND	Transcriptional regulator
A6E01_03895	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A6E01_03900	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
A6E01_03915	ENOG4108KB2	LysR family Transcriptional regulator
A6E01_03970	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
A6E01_03985	ENOG4107RSM	transcriptional regulator
A6E01_03995	ENOG41090WB	Transposase is3 is911
A6E01_04000	ENOG4105DZ1	carboxypeptidase
A6E01_04010	ENOG410600T	transposase
A6E01_04030	ENOG4105E68	Sulfatase
A6E01_04035	ENOG4105YDX	UPF0352 protein
A6E01_04040	ENOG4106V8H	Nucleoid-associated protein
A6E01_04045	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A6E01_04055	ENOG4105EYW	Ion transport protein
A6E01_04060	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A6E01_04065	ENOG4108EKI	Dehydrogenase
A6E01_04090	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
A6E01_04095	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A6E01_04100	ENOG4105M2J	Glutaredoxin
A6E01_04105	ENOG4105D3Y	Na H antiporter
A6E01_04110	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
A6E01_04115	ENOG4108UYE	Lactoylglutathione lyase
A6E01_04120	ENOG4105CSM	endonuclease III
A6E01_04125	ENOG4105DZB	Electron transport complex
A6E01_04130	ENOG4108UQQ	Electron transport complex
A6E01_04135	ENOG4105D6A	Electron transport complex
A6E01_04145	ENOG4108R3D	Electron transport complex
A6E01_04150	ENOG4105DGN	Electron transport complex
A6E01_04160	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A6E01_04165	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6E01_04175	ENOG4105CHW	UPF0052 protein
A6E01_04180	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A6E01_04185	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
A6E01_04190	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A6E01_04195	ENOG4105M00	molybdopterin converting factor, subunit 1
A6E01_04200	ENOG4108ZAF	Molybdopterin
A6E01_04205	ENOG4107QSI	ABC, transporter
A6E01_04210	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A6E01_04215	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A6E01_04220	ENOG4105C3U	ABC transporter
A6E01_04225	ENOG4108JQ7	(ABC) transporter
A6E01_04230	ENOG4105CHF	Glutathione S-transferase
A6E01_04265	ENOG4105BZS	acriflavin resistance protein
A6E01_04270	ENOG4105D03	DNA-3-methyladenine glycosylase II
A6E01_04285	ENOG4105F2V	VRR-NUC domain-containing protein
A6E01_04295	ENOG4108XM1	transcriptional regulator AsnC family
A6E01_04300	ENOG4105CK7	Sodium proline symporter
A6E01_04305	ENOG4105C29	acyl-CoA thioesterase
A6E01_04310	ENOG4108MNP	Glycoprotein polysaccharide metabolism
A6E01_04355	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A6E01_04360	ENOG4107T40	Inherit from COG: Glycosyltransferase 36
A6E01_04365	ENOG4107KJX	Transcriptional regulator
A6E01_04380	ENOG4105DRS	transport system, permease
A6E01_04390	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
A6E01_04400	ENOG4105CW7	secretion protein, HlyD family
A6E01_04420	ENOG4105C94	Transporter
A6E01_04425	ENOG4105E0U	tyrosine-specific transport protein
A6E01_04435	ENOG4105DR5	peptidase
A6E01_04440	ENOG4105CZQ	inner membrane transport protein YdhC
A6E01_04445	ENOG4105DU1	integral membrane protein, terc
A6E01_04450	ENOG4105CI2	imidazolone-5-propionate hydrolase
A6E01_04455	ENOG4105CHH	sulfate transporter
A6E01_04485	ENOG4105EKQ	RNA-directed DNA polymerase
A6E01_04515	ENOG4108RZ2	Glycoside hydrolase family 16
A6E01_04520	ENOG4105ETE	Transcriptional regulator (LacI family
A6E01_04530	ENOG4105MYN	Zinc uptake regulation protein
A6E01_04535	ENOG4105WJZ	Glutathione S-transferase, C-terminal domain
A6E01_04540	ENOG410600T	transposase
A6E01_04570	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
A6E01_04585	ENOG4105C5H	ABC transporter
A6E01_04590	ENOG4105CUW	cytochrome C-TYPE protein
A6E01_04595	ENOG4107QY8	reductase
A6E01_04610	ENOG4105F04	LysR family Transcriptional regulator
A6E01_04615	ENOG4105EQ0	Major Facilitator superfamily
A6E01_04625	ENOG4105EN6	Membrane
A6E01_04630	ENOG4105BZ4	penicillin-binding protein
A6E01_04640	ENOG4105C94	Transporter
A6E01_04660	ENOG4105CMU	LysR family (Transcriptional regulator
A6E01_04665	ENOG4105VAW	lrga family
A6E01_04670	ENOG41067MG	lrgb family
A6E01_04690	ENOG410600T	transposase
A6E01_04695	ENOG4105DVH	amino acid
A6E01_04720	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A6E01_04725	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
A6E01_04730	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
A6E01_04735	ENOG4105BZ7	extracellular solute-binding protein family 1
A6E01_04745	ENOG4105E98	transcriptional regulator DeoR family
A6E01_04755	ENOG4107R73	Mate efflux family protein
A6E01_04760	ENOG4105C3U	ABC transporter
A6E01_04765	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
A6E01_04775	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A6E01_04785	ENOG4105CXK	mandelate racemase muconate lactonizing
A6E01_04795	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
A6E01_04800	ENOG4108IEG	Formate dehydrogenase Alpha subunit
A6E01_04805	ENOG41066YJ	Beta-lactamase
A6E01_04815	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
A6E01_04830	ENOG4105P66	Membrane
A6E01_04840	ENOG4105EKT	)-iron permease
A6E01_04845	ENOG4105DZ2	Transcriptional regulator
A6E01_04850	ENOG4106HNH	Acyl-transferase
A6E01_04855	ENOG4108UW5	maltose o-acetyltransferase
A6E01_04860	ENOG4105C2C	drug resistance transporter, Bcr CflA
A6E01_04865	ENOG4105BZU	Histidine kinase
A6E01_04870	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A6E01_04885	ENOG4105ERG	peptidase m48, ste24p
A6E01_04895	ENOG4108IPW	abc transporter atp-binding protein
A6E01_04900	ENOG4105CM4	permease protein
A6E01_04905	ENOG4105DHS	permease protein
A6E01_04920	ENOG4105D05	Receptor
A6E01_04930	ENOG4105J12	Multidrug resistance protein mdtN
A6E01_04950	ENOG4108I5U	Uridine phosphorylase
A6E01_04960	ENOG4105K59	histidine triad (HIT) protein
A6E01_04980	ENOG4105D0Y	UPF0227 protein
A6E01_04985	ENOG4105CEP	NADH dehydrogenase
A6E01_04995	ENOG4108JA2	transcriptioN-repair coupling factor
A6E01_05000	ENOG4105D60	lipoprotein releasing system transmembrane protein
A6E01_05005	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A6E01_05010	ENOG4105D60	lipoprotein releasing system transmembrane protein
A6E01_05020	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
A6E01_05025	ENOG4105BZ1	(ABC) transporter
A6E01_05030	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
A6E01_05035	ENOG4105W49	UPF0434 protein
A6E01_05040	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
A6E01_05045	ENOG4105ED1	spovr family
A6E01_05050	ENOG4106AKX	UPF0229 protein
A6E01_05055	ENOG4105CYN	Serine protein kinase
A6E01_05065	ENOG4105XWI	UPF0304 protein
A6E01_05070	ENOG4105F1A	Pyruvate formate-lyase
A6E01_05080	ENOG4105C6N	Formate acetyltransferase
A6E01_05090	ENOG4108JEH	abc transporter atp-binding protein
A6E01_05095	ENOG4105E89	ABC transporter
A6E01_05100	ENOG4105DSP	amino acid AbC transporter
A6E01_05105	ENOG4106YG3	ABC transporter
A6E01_05110	ENOG4105CGK	Exodeoxyribonuclease III
A6E01_05115	ENOG4106428	Protein of unknown function (DUF2496)
A6E01_05125	ENOG4105EJ9	Membrane
A6E01_05130	ENOG4105DVT	helicase
A6E01_05140	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
A6E01_05145	ENOG4107QTF	adenylosuccinate lyase
A6E01_05150	ENOG41075W9	High frequency lysogenization protein HflD homolog
A6E01_05165	ENOG4108R99	pseudouridine synthase
A6E01_05175	ENOG4105D5Q	Arginine ornithine antiporter
A6E01_05190	ENOG4108RCM	Nitroreductase
A6E01_05200	ENOG4105VEQ	Cold shock protein
A6E01_05205	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
A6E01_05210	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A6E01_05215	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A6E01_05220	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
A6E01_05225	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
A6E01_05230	ENOG4107MBR	17 kDa surface antigen
A6E01_05235	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
A6E01_05240	ENOG4108UR8	BAX protein
A6E01_05245	ENOG4105RKX	Protein of unknown function (DUF2498)
A6E01_05250	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A6E01_05255	ENOG4107RE1	Inosine-guanosine kinase
A6E01_05265	ENOG4107S6Z	Na H antiporter
A6E01_05270	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
A6E01_05275	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
A6E01_05280	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A6E01_05285	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
A6E01_05300	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
A6E01_05305	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
A6E01_05310	ENOG4105K5B	UPF0225 protein
A6E01_05315	ENOG4105D58	Diguanylate phosphodiesterase
A6E01_05320	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
A6E01_05325	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A6E01_05330	ENOG4105C8N	cysteinyl-tRNA synthetase
A6E01_05335	ENOG4107104	thymidine kinase
A6E01_05340	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A6E01_05350	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A6E01_05355	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
A6E01_05360	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
A6E01_05365	ENOG4108JQ2	peptide transport system atp-binding protein
A6E01_05370	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
A6E01_05375	ENOG4108EU3	peptide transport system, permease
A6E01_05380	ENOG4108I5W	peptide transport system, permease protein
A6E01_05385	ENOG4108J59	Extracellular solute-binding protein, family 5
A6E01_05390	ENOG4105E51	psp operon transcriptional activator
A6E01_05395	ENOG41087YS	Phage shock protein A
A6E01_05400	ENOG4105YYT	phage shock protein B
A6E01_05415	ENOG4105DUX	Transporter
A6E01_05430	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
A6E01_05460	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A6E01_05470	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
A6E01_05475	ENOG4108JUA	Transcriptional regulator
A6E01_05480	ENOG4105DP0	ferredoxin-NADP reductase
A6E01_05505	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
A6E01_05530	ENOG4105EZE	Cupin 4 family protein
A6E01_05540	ENOG4105C28	cystathionine
A6E01_05550	ENOG4108W1A	pseudouridine synthase
A6E01_05555	ENOG4105DR4	Methyltransferase
A6E01_05565	ENOG4105K9H	YciI-like protein
A6E01_05570	ENOG4105NAU	thioesterase Superfamily protein
A6E01_05575	ENOG4107835	probably involved in intracellular septation (By similarity)
A6E01_05600	ENOG4105UBK	short-chain dehydrogenase reductase
A6E01_05620	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
A6E01_05625	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A6E01_05630	ENOG4105DK0	Indole-3-glycerol phosphate synthase
A6E01_05635	ENOG4108I0Q	anthranilate phosphoribosyltransferase
A6E01_05640	ENOG4105DDQ	anthranilate synthase
A6E01_05645	ENOG4105CRQ	synthase (Component I)
A6E01_05650	ENOG4105DB7	PHP domain protein
A6E01_05655	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
A6E01_05660	ENOG4105FE9	pseudouridine synthase
A6E01_05665	ENOG4105K63	Thioredoxin
A6E01_05680	ENOG4107YFT	Nadph-dependent fmn reductase
A6E01_05700	ENOG4105JAB	phenazine biosynthesis protein, phzf family
A6E01_05705	ENOG4105C5I	Dehydrogenase
A6E01_05725	ENOG4108WFC	UPF0438 protein yifE
A6E01_05735	ENOG4105BZ1	(ABC) transporter
A6E01_05775	ENOG4108W5H	UPF0263 protein
A6E01_05780	ENOG4105CQ2	DNA polymerase
A6E01_05785	ENOG4105WH1	Two component transcriptional regulator luxr family
A6E01_05790	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
A6E01_05855	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
A6E01_05860	ENOG4105DQF	Hydrolase
A6E01_05865	ENOG4106R3P	AraC family transcriptional regulator
A6E01_05875	ENOG4105ENH	Sulfatase
A6E01_05885	ENOG4105RKW	reductase (By
A6E01_05890	ENOG4105ES4	Nitrilase
A6E01_05900	ENOG4105D0C	transport protein
A6E01_05930	ENOG4105DWD	nucleoside recognition domain protein
A6E01_05935	ENOG4105C8V	SAICAR synthetase
A6E01_05955	ENOG4105CQB	FAD linked oxidase domain protein
A6E01_05995	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
A6E01_06000	ENOG4105F8D	glycoside hydrolase family 4
A6E01_06005	ENOG4105ETT	transcriptional Regulator, LysR family
A6E01_06015	ENOG4105C22	threonyL-tRNA synthetase
A6E01_06020	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
A6E01_06025	ENOG41082NX	50s ribosomal protein l35
A6E01_06030	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
A6E01_06045	ENOG4105KHC	sulfurtransferase
A6E01_06070	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A6E01_06075	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
A6E01_06080	ENOG4105C1J	atp-dependent rna helicase
A6E01_06095	ENOG4105D9P	serine threonine protein kinase
A6E01_06120	ENOG4108Z7F	N-acetyltransferase
A6E01_06150	ENOG4105EW6	flavin reductase domain protein, FMN-binding
A6E01_06155	ENOG4105JAB	phenazine biosynthesis protein, phzf family
A6E01_06165	ENOG4105I08	Pseudouridine synthase
A6E01_06185	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A6E01_06190	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
A6E01_06195	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
A6E01_06200	ENOG41067MG	lrgb family
A6E01_06205	ENOG4105VAW	lrga family
A6E01_06210	ENOG4105CJB	Exodeoxyribonuclease I
A6E01_06220	ENOG4108ETY	sodium dicarboxylate symporter
A6E01_06230	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
A6E01_06240	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
A6E01_06265	ENOG4105EE0	oxidoreductase
A6E01_06270	ENOG4107YWA	deoxycytidylate deaminase
A6E01_06280	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
A6E01_06295	ENOG4105CGY	Dna recombination protein
A6E01_06300	ENOG4108UUM	single-stranded DNA-binding protein
A6E01_06320	ENOG4107RH8	nuclease SbcCD subunit D
A6E01_06325	ENOG4105EYH	Exonuclease
A6E01_06365	ENOG4105CD3	dihydroorotase
A6E01_06395	ENOG4108RXX	maleylacetoacetate isomerase
A6E01_06405	ENOG4105CNH	Multidrug resistance protein MdtL
A6E01_06425	ENOG4105EGI	Transcriptional regulator
A6E01_06435	ENOG4107QI1	Mate efflux family protein
A6E01_06440	ENOG4108R6K	riboflavin synthase, subunit alpha
A6E01_06450	ENOG4105FGM	Fructosamine kinase
A6E01_06455	ENOG4107TT5	NLP P60 protein
A6E01_06465	ENOG4106IUH	DTW domain containing protein
A6E01_06470	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
A6E01_06495	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A6E01_06515	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
A6E01_06520	ENOG4105Q9Y	Universal stress protein
A6E01_06525	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
A6E01_06535	ENOG4105C59	p-type ATPase
A6E01_06545	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
A6E01_06560	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
A6E01_06570	ENOG4105DJ2	Major Facilitator Superfamily
A6E01_06590	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
A6E01_06595	ENOG4105DAN	ATP-dependent protease
A6E01_06600	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
A6E01_06615	ENOG4105C5H	ABC transporter
A6E01_06625	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A6E01_06630	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
A6E01_06635	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
A6E01_06640	ENOG4105C7I	Dehydrogenase
A6E01_06655	ENOG4105CN1	protease
A6E01_06660	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
A6E01_06665	ENOG4108ZGC	gaf domain protein
A6E01_06670	ENOG4105H2K	paraquat-inducible protein a
A6E01_06675	ENOG4105DY2	Paraquat-inducible protein b
A6E01_06680	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A6E01_06690	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
A6E01_06695	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A6E01_06700	ENOG4108VPT	UPF0234 protein
A6E01_06705	ENOG4108ISG	Major Facilitator
A6E01_06710	ENOG4105K63	Thioredoxin
A6E01_06720	ENOG4107QXX	ABC transporter
A6E01_06725	ENOG4105EZ7	amino acid ABC transporter
A6E01_06730	ENOG4105DRP	amino acid AbC transporter
A6E01_06735	ENOG4105CDA	abc transporter atp-binding protein
A6E01_06740	ENOG4108MN8	Membrane
A6E01_06745	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
A6E01_06750	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
A6E01_06770	ENOG4105KCK	Peptidoglycan-associated lipoprotein
A6E01_06780	ENOG410667J	hydrolase
A6E01_06800	ENOG4105BZG	amino acid carrier protein
A6E01_06805	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A6E01_06810	ENOG4105EHG	Permease protein
A6E01_06830	ENOG4105CTD	carboxy-peptidase
A6E01_06845	ENOG4105BZU	Histidine kinase
A6E01_06875	ENOG4107KGK	dmso reductase anchor subunit
A6E01_06880	ENOG4105QAX	Iron-sulfur
A6E01_06885	ENOG4107QY8	reductase
A6E01_06890	ENOG4108NEM	leader-binding protein dmsD
A6E01_06905	ENOG4105CQ7	ATP-dependent helicase
A6E01_06940	ENOG4105CFG	Acts as a chaperone (By similarity)
A6E01_06945	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
A6E01_06950	ENOG4105E0X	reductase
A6E01_06955	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
A6E01_06970	ENOG4105D9U	N-acetyltransferase
A6E01_06975	ENOG4108JU8	Transcriptional regulator
A6E01_06980	ENOG4106K28	UPF0283 membrane protein
A6E01_06985	ENOG4105CM6	amino acid regulated cytosolic protein
A6E01_07000	ENOG4105CRQ	synthase (Component I)
A6E01_07005	ENOG4105P8F	nudix hydrolase
A6E01_07010	ENOG4105C5S	asparaginyl-tRNA synthetase
A6E01_07015	ENOG4105CGF	Aromatic amino acid aminotransferase
A6E01_07030	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
A6E01_07040	ENOG41060QA	UPF0267 protein
A6E01_07045	ENOG4105C94	Transporter
A6E01_07050	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
A6E01_07060	ENOG4105CH5	extracellular solute-binding protein, family 7
A6E01_07070	ENOG4105C5X	domain protein
A6E01_07075	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
A6E01_07080	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
A6E01_07085	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A6E01_07090	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
A6E01_07095	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A6E01_07100	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A6E01_07115	ENOG4108I62	cina-like protein
A6E01_07125	ENOG4107QPN	acyl-Coa dehydrogenase
A6E01_07130	ENOG4108RZE	Tetr family transcriptional regulator
A6E01_07135	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A6E01_07150	ENOG4105C19	ABC transporter
A6E01_07155	ENOG4105CGD	Nad-dependent epimerase dehydratase
A6E01_07165	ENOG4105C2C	drug resistance transporter, Bcr CflA
A6E01_07170	ENOG4105I08	Pseudouridine synthase
A6E01_07175	ENOG4105CFI	type iii restriction protein res subunit
A6E01_07180	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
A6E01_07185	ENOG4105DYB	Isoaspartyl dipeptidase
A6E01_07190	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A6E01_07205	ENOG4108JQ6	ABC transporter
A6E01_07210	ENOG4105XZD	Fe-S protein
A6E01_07225	ENOG4107R1I	NAD-dependent malic enzyme
A6E01_07230	ENOG4107GZ4	SanA protein
A6E01_07235	ENOG4105C3M	thioredoxin reductase
A6E01_07240	ENOG4108JJ9	ABC, transporter
A6E01_07245	ENOG4108JJ8	(ABC) transporter
A6E01_07250	ENOG4105CIS	alcohol dehydrogenase
A6E01_07255	ENOG4105EJC	lysr family transcriptional regulator
A6E01_07260	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
A6E01_07270	ENOG4105BZU	Histidine kinase
A6E01_07300	ENOG4105CCT	upf0313 protein
A6E01_07315	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
A6E01_07330	ENOG4108J59	Extracellular solute-binding protein, family 5
A6E01_07345	ENOG4105BZS	acriflavin resistance protein
A6E01_07360	ENOG4105DWU	Membrane
A6E01_07370	ENOG4105DY8	decarboxylase
A6E01_07375	ENOG4106KNT	transcriptional regulator
A6E01_07380	ENOG4105C0A	alcohol dehydrogenase
A6E01_07385	ENOG41090BQ	Glutaredoxin
A6E01_07390	ENOG4105DUX	Transporter
A6E01_07405	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
A6E01_07410	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A6E01_07415	ENOG4105DXD	2-methylcitrate dehydratase
A6E01_07420	ENOG4105BZN	citrate synthase
A6E01_07425	ENOG4105CR4	methylisocitrate lyase
A6E01_07435	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
A6E01_07460	ENOG4108YZN	class I peptide chain release factor
A6E01_07470	ENOG4107S6Z	Na H antiporter
A6E01_07475	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
A6E01_07480	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
A6E01_07490	ENOG4108NWD	Cytochrome
A6E01_07520	ENOG4108UT2	hemolysin iii
A6E01_07535	ENOG4105D5T	phosphonate abc transporter
A6E01_07555	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
A6E01_07565	ENOG4105CI1	PTS System
A6E01_07570	ENOG4105C8P	)-transporter
A6E01_07590	ENOG4105C59	p-type ATPase
A6E01_07595	ENOG4105W1Y	Transcriptional regulator
A6E01_07615	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
A6E01_07620	ENOG4105K63	Thioredoxin
A6E01_07625	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A6E01_07635	ENOG4105K3M	)-transporter
A6E01_07645	ENOG4105CFP	Peptidase U32
A6E01_07660	ENOG4105ECR	NmrA family
A6E01_07685	ENOG41082BV	acetyltransferase
A6E01_07695	ENOG4105C1J	atp-dependent rna helicase
A6E01_07710	ENOG4105QAX	Iron-sulfur
A6E01_07715	ENOG4108JB9	formate dehydrogenase
A6E01_07745	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
A6E01_07755	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
A6E01_07770	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A6E01_07780	ENOG4108UYE	Lactoylglutathione lyase
A6E01_07785	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A6E01_07795	ENOG4105E39	Enoyl-CoA hydratase
A6E01_07805	ENOG4105BZ8	glutamate synthase
A6E01_07810	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A6E01_07825	ENOG4105D3G	Pseudouridine synthase
A6E01_07830	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A6E01_07835	ENOG4105WZW	rhodanese family
A6E01_07845	ENOG4105CEY	Amp-dependent synthetase and ligase
A6E01_07850	ENOG4105D6U	Sodium Glutamate Symporter
A6E01_07880	ENOG4108YUH	
A6E01_07890	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
A6E01_07895	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
A6E01_07920	ENOG4105ER2	Ompa motb domain protein
A6E01_07950	ENOG410600T	transposase
A6E01_08000	ENOG4105DFP	Integrase
A6E01_08015	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A6E01_08020	ENOG4105UFD	tol-pal system protein YbgF
A6E01_08025	ENOG4105KCK	Peptidoglycan-associated lipoprotein
A6E01_08030	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
A6E01_08040	ENOG4105M8F	Biopolymer transport protein exbD tolR
A6E01_08045	ENOG4105E02	MotA TolQ exbB proton channel
A6E01_08050	ENOG4107YD3	Thioesterase
A6E01_08065	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A6E01_08070	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A6E01_08080	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
A6E01_08085	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
A6E01_08090	ENOG4105C9M	aspartyl-trna synthetase
A6E01_08095	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
A6E01_08105	ENOG4107QY8	reductase
A6E01_08135	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
A6E01_08140	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
A6E01_08145	ENOG4106371	Methyltransferase
A6E01_08150	ENOG4107S90	membrAne
A6E01_08155	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
A6E01_08160	ENOG4105ETE	Transcriptional regulator (LacI family
A6E01_08185	ENOG4105RHG	
A6E01_08195	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
A6E01_08210	ENOG4107FW0	short-chain dehydrogenase reductase
A6E01_08220	ENOG4105D0M	Protease HtpX homolog
A6E01_08225	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
A6E01_08230	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
A6E01_08235	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A6E01_08240	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
A6E01_08245	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A6E01_08250	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A6E01_08255	ENOG4105D1H	recombination factor protein RarA
A6E01_08260	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
A6E01_08265	ENOG4105CNU	cell division protein FtsK
A6E01_08270	ENOG4105EW9	transcriptional regulator AsnC family
A6E01_08275	ENOG4105DCF	alanine dehydrogenase
A6E01_08285	ENOG4107R11	Transcriptional regulator
A6E01_08290	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
A6E01_08295	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A6E01_08300	ENOG4105CFV	Tetratricopeptide repeat protein
A6E01_08305	ENOG4105Q4A	inner membrane protein yciS
A6E01_08310	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A6E01_08315	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A6E01_08320	ENOG4105CAT	Cytidine monophosphate kinase
A6E01_08330	ENOG4105ERU	peptidase
A6E01_08335	ENOG4105UBK	short-chain dehydrogenase reductase
A6E01_08340	ENOG4108RU0	short-chain dehydrogenase reductase
A6E01_08345	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A6E01_08350	ENOG41069NU	Nitroreductase
A6E01_08355	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A6E01_08360	ENOG4105D07	Signal peptide peptidase, SppA
A6E01_08365	ENOG4105HDK	L-asparaginase
A6E01_08375	ENOG4105VUT	cytoplasmic protein
A6E01_08380	ENOG4105E0X	reductase
A6E01_08390	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
A6E01_08395	ENOG4105DSB	aldose 1-epimerase
A6E01_08400	ENOG4105DHI	Methyltransferase
A6E01_08410	ENOG4108ZZ3	UPF0260 protein
A6E01_08415	ENOG4105KRS	Proteinase inhibitor
A6E01_08420	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
A6E01_08425	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
A6E01_08430	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
A6E01_08435	ENOG4107QMP	dna polymerase iii subunits gamma and tau
A6E01_08440	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A6E01_08445	ENOG4105WD1	Membrane
A6E01_08450	ENOG4105I93	response regulator
A6E01_08455	ENOG4105EJC	lysr family transcriptional regulator
A6E01_08460	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
A6E01_08465	ENOG4105E96	Colicin v production protein
A6E01_08470	ENOG4108S3P	Sporulation domain protein
A6E01_08475	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
A6E01_08480	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
A6E01_08485	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A6E01_08495	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A6E01_08500	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
A6E01_08505	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A6E01_08510	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
A6E01_08520	ENOG4105MH2	YfcL protein
A6E01_08525	ENOG4108BPE	-transporting atpase
A6E01_08530	ENOG4105EN6	Membrane
A6E01_08545	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
A6E01_08550	ENOG4108DG9	Smr protein MutS2
A6E01_08560	ENOG4108BY2	phosphohistidine phosphatase
A6E01_08565	ENOG4107QXK	peptidase
A6E01_08580	ENOG4105CHU	acetyl-coa acetyltransferase
A6E01_08595	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
A6E01_08605	ENOG410903C	(LipO)protein
A6E01_08610	ENOG4105KWW	Biogenesis protein
A6E01_08615	ENOG4108M1T	Cytochrome c-type biogenesis protein
A6E01_08620	ENOG4107QX9	Thiol disulfide interChange protein
A6E01_08625	ENOG4105DA4	cytochrome c-type biogenesis protein
A6E01_08640	ENOG41060IM	Heme exporter protein
A6E01_08645	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
A6E01_08650	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
A6E01_08665	ENOG41064T2	transcriptional regulator, lysR family
A6E01_08670	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
A6E01_08675	ENOG4105EIP	mannose-6-phosphate isomerase
A6E01_08680	ENOG4105BZW	Glycerate kinase
A6E01_08685	ENOG4105C8I	hydrolase, family 38
A6E01_08690	ENOG4105DM4	PTS System
A6E01_08695	ENOG4105FDP	GntR family transcriptional regulator
A6E01_08705	ENOG4108AEY	RNA polymerase sigma factor
A6E01_08715	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
A6E01_08720	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A6E01_08730	ENOG4105CEE	C4-dicarboxylate transporter
A6E01_08740	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
A6E01_08750	ENOG4108GAE	asmA family
A6E01_08755	ENOG4105DBI	uridine monophosphokinase
A6E01_08760	ENOG4105D1F	ATP-binding protein
A6E01_08765	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A6E01_08775	ENOG4105DAG	ROK family
A6E01_08780	ENOG4108NRW	Phospholipase, patatin family
A6E01_08790	ENOG4105C8J	)-transporter
A6E01_08800	ENOG4105CI1	PTS System
A6E01_08805	ENOG4105F8V	Hydrolase, tatD family
A6E01_08810	ENOG4107QRG	dna polymerase iii
A6E01_08815	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A6E01_08820	ENOG4105HHA	aminodeoxychorismate lyase
A6E01_08830	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A6E01_08835	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A6E01_08840	ENOG4105CHR	reductase
A6E01_08845	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A6E01_08850	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A6E01_08855	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
A6E01_08860	ENOG4105VGS	50s ribosomal protein l32
A6E01_08865	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
A6E01_08875	ENOG4105EI2	Pseudouridine synthase
A6E01_08880	ENOG4105C03	ribonuclease
A6E01_08885	ENOG4105CHH	sulfate transporter
A6E01_08920	ENOG4105CPC	Aldo Keto reductase
A6E01_08935	ENOG4105DKK	Benzoate
A6E01_08940	ENOG4108JCI	Transcriptional regulator
A6E01_08945	ENOG4105DFI	Membrane
A6E01_08950	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
A6E01_08965	ENOG4105RK9	auxin efflux carrier
A6E01_08975	ENOG4108UTZ	Dihydroxyacetone kinase
A6E01_08980	ENOG4105CMT	Dihydroxyacetone kinase
A6E01_08985	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
A6E01_08990	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
A6E01_09000	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
A6E01_09005	ENOG4108YZG	isomerase
A6E01_09010	ENOG4105CBT	Fructose-1,6-bisphosphatase
A6E01_09050	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A6E01_09055	ENOG4105CVE	Lytic murein transglycosylase
A6E01_09065	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
A6E01_09070	ENOG4107QMS	site-determining protein
A6E01_09075	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
A6E01_09080	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
A6E01_09085	ENOG4105CEY	Amp-dependent synthetase and ligase
A6E01_09100	ENOG41072GX	Peptidase M22 Glycoprotease
A6E01_09105	ENOG4105DVT	helicase
A6E01_09110	ENOG4105CIY	formyltetrahydrofolate deformylase
A6E01_09115	ENOG4106ZCM	YecM protein
A6E01_09120	ENOG4105C75	arginyL-tRNA synthetase
A6E01_09125	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
A6E01_09140	ENOG4107QI1	Mate efflux family protein
A6E01_09145	ENOG4105ETT	transcriptional Regulator, LysR family
A6E01_09150	ENOG4105C8J	)-transporter
A6E01_09175	ENOG4105XFK	Ferrous iron transport protein A
A6E01_09180	ENOG4105NXV	High-affinity zinc uptake system protein
A6E01_09185	ENOG4105FDK	ABC transporter
A6E01_09190	ENOG4105FAV	ABC, transporter
A6E01_09195	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
A6E01_09200	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
A6E01_09205	ENOG4105C7S	Dehydrogenase
A6E01_09210	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
A6E01_09215	ENOG4105E33	succinate dehydrogenase
A6E01_09225	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
A6E01_09230	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
A6E01_09235	ENOG4105BZN	citrate synthase
A6E01_09240	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
A6E01_09270	ENOG41060NJ	transcriptional regulator
A6E01_09275	ENOG4107QNR	UPF0135 protein
A6E01_09285	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
A6E01_09290	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
A6E01_09295	ENOG4105EV9	Alpha Beta Hydrolase
A6E01_09305	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
A6E01_09310	ENOG41090R7	Ferric uptake
A6E01_09325	ENOG4105CI1	PTS System
A6E01_09330	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
A6E01_09335	ENOG4105CE4	GlcNAc 6-P deacetylase
A6E01_09340	ENOG4105E2R	ROK family
A6E01_09345	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A6E01_09355	ENOG4105CAQ	asparagine synthetase
A6E01_09360	ENOG4105MDZ	Transcriptional activator rfaH
A6E01_09365	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
A6E01_09370	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A6E01_09375	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
A6E01_09380	ENOG4108DQ1	activator toxR
A6E01_09390	ENOG4108RE9	Phosphodiesterase
A6E01_09415	ENOG4105ECP	epimerase
A6E01_09420	ENOG4107QR8	Thioredoxin
A6E01_09425	ENOG4107QX8	SPFH domain, Band 7 family protein
A6E01_09435	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A6E01_09440	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
A6E01_09445	ENOG4105EXN	Sulfate transport protein CysZ
A6E01_09450	ENOG4105C6T	cysteine synthase
A6E01_09455	ENOG4105KZ7	phosphocarrier protein hpr
A6E01_09465	ENOG4105C5Y	PTS System
A6E01_09470	ENOG4105EZR	dyp-type peroxidase family protein
A6E01_09475	ENOG4105QZU	Inner membrane protein YfeZ
A6E01_09490	ENOG4105KUZ	arsenate reductase
A6E01_09495	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A6E01_09510	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A6E01_09520	ENOG4105RH4	Glycine cleavage system transcriptional repressor
A6E01_09525	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A6E01_09535	ENOG4105ERG	peptidase m48, ste24p
A6E01_09540	ENOG4105K89	arsenate reductase
A6E01_09550	ENOG4105DSG	hydrolase family 43
A6E01_09560	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A6E01_09565	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A6E01_09570	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
A6E01_09585	ENOG4105E7A	Glutamine amidotransferase
A6E01_09590	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
A6E01_09595	ENOG4107QPN	acyl-Coa dehydrogenase
A6E01_09600	ENOG4108JDX	DNA polymerase iii, epsilon subunit
A6E01_09605	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A6E01_09610	ENOG4105D1A	Methyltransferase
A6E01_09620	ENOG4105E9H	Lytic Murein transglycosylase
A6E01_09625	ENOG4107NA1	Endonuclease Exonuclease phosphatase
A6E01_09630	ENOG4108YZA	Nitrogen regulatory protein pii
A6E01_09635	ENOG4105N7H	Cytochrome
A6E01_09640	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A6E01_09645	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
A6E01_09650	ENOG4105C0B	DNA polymerase III (alpha subunit)
A6E01_09655	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A6E01_09665	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A6E01_09670	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
A6E01_09675	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A6E01_09680	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
A6E01_09685	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A6E01_09690	ENOG4105DZP	Membrane-associated zinc metalloprotease
A6E01_09695	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
A6E01_09700	ENOG4105KNE	Phosphatidate cytidylyltransferase
A6E01_09705	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A6E01_09710	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
A6E01_09715	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A6E01_09725	ENOG4105CE9	30S ribosomal protein S2
A6E01_09730	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A6E01_09735	ENOG4105DHT	Metal Dependent Phosphohydrolase
A6E01_09740	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
A6E01_09745	ENOG4108T8E	UPF0325 protein
A6E01_09750	ENOG4105DR9	pseudouridine synthase
A6E01_09755	ENOG4105WP7	tRNA pseudouridine synthase C
A6E01_09780	ENOG4108UPT	UPF0178 protein
A6E01_09785	ENOG4105DZ0	fad dependent oxidoreductase
A6E01_09790	ENOG4108Z4U	Ferredoxin
A6E01_09800	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
A6E01_09805	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
A6E01_09810	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
A6E01_09820	ENOG4105EWT	decarboxylase family
A6E01_09825	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
A6E01_09830	ENOG4105EQR	Transposase IS116 IS110 IS902
A6E01_09835	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
A6E01_09840	ENOG4105ETT	transcriptional Regulator, LysR family
A6E01_09845	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A6E01_09850	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A6E01_09855	ENOG4105CTB	Polyprenyl synthetase
A6E01_09860	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
A6E01_09865	ENOG4108ZAI	phosphatidylglycerophosphatase a
A6E01_09870	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A6E01_09875	ENOG4107YIM	Involved in the transcription termination process (By similarity)
A6E01_09880	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
A6E01_09895	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
A6E01_09900	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
A6E01_09905	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
A6E01_09910	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
A6E01_09915	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
A6E01_09925	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
A6E01_09930	ENOG4105C7N	Xanthine uracil vitamin C permease
A6E01_09935	ENOG4105CIN	aminoacyl-histidine dipeptidase
A6E01_09945	ENOG4108ETH	Formylglycinamide ribotide synthetase
A6E01_09950	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
A6E01_09955	ENOG4108Z6B	deaminase
A6E01_09970	ENOG4105C4W	S-formylglutathione hydrolase
A6E01_09975	ENOG4105CFC	Transporter
A6E01_10000	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A6E01_10005	ENOG4105CFG	Acts as a chaperone (By similarity)
A6E01_10010	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A6E01_10015	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A6E01_10020	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
A6E01_10025	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A6E01_10030	ENOG4105VDB	UPF0125 protein
A6E01_10035	ENOG4108Z1B	Cyclase dehydrase
A6E01_10040	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
A6E01_10050	ENOG4105DUM	transcriptional regulator, lysR family
A6E01_10060	ENOG4105K6T	rare lipoprotein A
A6E01_10075	ENOG4105CHR	reductase
A6E01_10080	ENOG4105M5J	Cupin 2, conserved barrel domain protein
A6E01_10085	ENOG4107RJ1	sodium solute
A6E01_10090	ENOG4105D2H	Uronic isomerase
A6E01_10105	ENOG4105E5Q	amino acid AbC transporter
A6E01_10110	ENOG4105E5Q	amino acid AbC transporter
A6E01_10115	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
A6E01_10120	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A6E01_10125	ENOG4108JPW	Aminotransferase
A6E01_10135	ENOG4105EMU	Dehydrogenase
A6E01_10140	ENOG4105CN8	Transcriptional regulator
A6E01_10145	ENOG4107RJ1	sodium solute
A6E01_10150	ENOG4108UW5	maltose o-acetyltransferase
A6E01_10185	ENOG4105D6J	arsenicaL-resistance protein
A6E01_10195	ENOG4105DUM	transcriptional regulator, lysR family
A6E01_10200	ENOG4105TMB	Formate nitrite transporter
A6E01_10205	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
A6E01_10210	ENOG4108VGW	abc transporter atp-binding protein
A6E01_10215	ENOG4105CXZ	ABC transporter, permease
A6E01_10220	ENOG4105VNH	ABC transporter solute-binding protein
A6E01_10225	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
A6E01_10230	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A6E01_10235	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A6E01_10240	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A6E01_10250	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A6E01_10255	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A6E01_10260	ENOG4105N21	Membrane
A6E01_10265	ENOG4105CUT	histidyl-tRNA synthetase
A6E01_10270	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
A6E01_10285	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
A6E01_10290	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A6E01_10295	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A6E01_10300	ENOG4105WVQ	Fe-S assembly protein IscX
A6E01_10305	ENOG4108ZIT	Ferredoxin, 2FE-2S
A6E01_10310	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
A6E01_10315	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
A6E01_10320	ENOG4108Z4V	iron-sulfur cluster assembly
A6E01_10325	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
A6E01_10330	ENOG4105C3J	Cysteine desulfurase
A6E01_10335	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
A6E01_10340	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
A6E01_10345	ENOG4105ECY	inositol monophosphatase
A6E01_10350	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A6E01_10355	ENOG4105EEI	dihydropteroate synthase
A6E01_10360	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A6E01_10365	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
A6E01_10370	ENOG4105HBR	Rna-binding protein
A6E01_10375	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A6E01_10385	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
A6E01_10390	ENOG4105CJW	magnesium transporter
A6E01_10395	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A6E01_10400	ENOG4105DR5	peptidase
A6E01_10415	ENOG4105Y49	secretion protein, HlyD family
A6E01_10420	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
A6E01_10425	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
A6E01_10430	ENOG4105IPI	Membrane
A6E01_10440	ENOG4105BZU	Histidine kinase
A6E01_10445	ENOG4107QRA	Extracellular solute-binding protein, family 5
A6E01_10460	ENOG4105C3U	ABC transporter
A6E01_10465	ENOG4108JQ7	(ABC) transporter
A6E01_10475	ENOG4105E2D	ec 3.2.1.52
A6E01_10480	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A6E01_10490	ENOG4107QKW	extracellular solute-binding protein family 1
A6E01_10500	ENOG4108YZA	Nitrogen regulatory protein pii
A6E01_10505	ENOG4105XTV	UPF0231 protein
A6E01_10510	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
A6E01_10515	ENOG4107QQ0	gntp family
A6E01_10520	ENOG4105BZW	Glycerate kinase
A6E01_10525	ENOG4107QIJ	Aconitate hydratase 2
A6E01_10530	ENOG4105D78	K07001 NTE family protein
A6E01_10535	ENOG4105BZ4	penicillin-binding protein
A6E01_10540	ENOG4105CQ7	ATP-dependent helicase
A6E01_10545	ENOG4105PW4	Sugar fermentation stimulation protein homolog
A6E01_10550	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A6E01_10560	ENOG4105DJ0	Poly(A) Polymerase
A6E01_10565	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A6E01_10570	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
A6E01_10575	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
A6E01_10580	ENOG4105E3A	(ABC) transporter
A6E01_10585	ENOG4105DA5	(ABC) transporter
A6E01_10590	ENOG41077A9	carbonic anhydrase
A6E01_10595	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A6E01_10600	ENOG4107QN2	dihydrolipoyl dehydrogenase
A6E01_10605	ENOG4107QSN	dihydrolipoamide acetyltransferase
A6E01_10610	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
A6E01_10615	ENOG41073TP	transcriptional regulator
A6E01_10625	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A6E01_10635	ENOG4107QHF	type ii secretion system protein e
A6E01_10640	ENOG4105D7Q	type ii secretion system
A6E01_10645	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
A6E01_10650	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A6E01_10655	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
A6E01_10660	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
A6E01_10665	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
A6E01_10670	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
A6E01_10675	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
A6E01_10680	ENOG4105K5M	30s ribosomal protein S16
A6E01_10685	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A6E01_10690	ENOG4106KVJ	cytochrome C assembly protein
A6E01_10695	ENOG4108JU6	CBS domain protein
A6E01_10700	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
A6E01_10705	ENOG4105D9M	gamma-glutamylcysteine synthetase
A6E01_10715	ENOG4105W39	Membrane
A6E01_10720	ENOG4105D9Q	decarboxylase (Beta subunit)
A6E01_10725	ENOG4107QSA	Oxaloacetate decarboxylase
A6E01_10775	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
A6E01_10780	ENOG4105CFH	Aspartokinase
A6E01_10785	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A6E01_10790	ENOG4105Y3E	Modulates RecA activity (By similarity)
A6E01_10795	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A6E01_10805	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A6E01_10810	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A6E01_10815	ENOG4108K5P	(LipO)protein
A6E01_10820	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A6E01_10825	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A6E01_10830	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
A6E01_10835	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
A6E01_10840	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
A6E01_10845	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
A6E01_10850	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A6E01_10855	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A6E01_10860	ENOG4105DXN	mazG family
A6E01_10865	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A6E01_10870	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A6E01_10875	ENOG4105BZU	Histidine kinase
A6E01_10880	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
A6E01_10885	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
A6E01_10895	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
A6E01_10900	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
A6E01_10905	ENOG4105C3F	Signal peptidase i
A6E01_10910	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
A6E01_10920	ENOG4105VQK	sigma E regulatory protein, MucB RseB
A6E01_10935	ENOG4108IYU	L-aspartate oxidase
A6E01_10940	ENOG4105Y75	tpr repeat protein
A6E01_10945	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
A6E01_10960	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
A6E01_10965	ENOG4105D0A	hydroxylase
A6E01_10975	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
A6E01_10985	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
A6E01_10995	ENOG4108JQ1	Dehydrogenase
A6E01_11005	ENOG4105D64	Mechanosensitive ion channel
A6E01_11010	ENOG4105D2N	Aldolase
A6E01_11020	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
A6E01_11025	ENOG4105CV1	Transketolase (EC 2.2.1.1)
A6E01_11030	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
A6E01_11040	ENOG4105GPY	SprT protein
A6E01_11045	ENOG4105RWS	endonuclease I
A6E01_11050	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
A6E01_11060	ENOG4108UJU	UPF0301 protein
A6E01_11065	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
A6E01_11070	ENOG4105CZX	twitching motility protein
A6E01_11075	ENOG4105CZX	twitching motility protein
A6E01_11080	ENOG4105DFA	alanine racemase domain protein
A6E01_11085	ENOG4105II7	pyrroline-5-carboxylate reductase
A6E01_11090	ENOG4108VIA	integral membrane protein
A6E01_11100	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A6E01_11105	ENOG4105CSA	Coproporphyrinogen iii oxidase
A6E01_11110	ENOG4105CSV	Glutaminase
A6E01_11120	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
A6E01_11125	ENOG4105CEN	a g-specific adenine glycosylase
A6E01_11130	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
A6E01_11200	ENOG4105CTS	PTS system mannitol-specific
A6E01_11205	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
A6E01_11210	ENOG4105E61	Mannitol repressor protein
A6E01_11215	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
A6E01_11220	ENOG410804X	Transcriptional regulator
A6E01_11225	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A6E01_11230	ENOG4105T16	Transcriptional regulator (AraC family)
A6E01_11235	ENOG4105C93	Xylose Isomerase
A6E01_11245	ENOG4105DT9	hydrolase family 43
A6E01_11255	ENOG4105DRS	transport system, permease
A6E01_11270	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A6E01_11275	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A6E01_11280	ENOG4105C93	Xylose Isomerase
A6E01_11285	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
A6E01_11290	ENOG4105CV1	Transketolase (EC 2.2.1.1)
A6E01_11295	ENOG4105CMG	Carbohydrate kinase
A6E01_11310	ENOG4108K5H	permease YjgP YjgQ family protein
A6E01_11315	ENOG4108M8S	permease YjgP YjgQ family protein
A6E01_11320	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A6E01_11325	ENOG4105MYG	DNA polymerase iii, chi subunit
A6E01_11330	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A6E01_11350	ENOG4105CEU	Arginine dihydrolase
A6E01_11355	ENOG4105DBV	ornithine carbamoyltransferase
A6E01_11360	ENOG4105CXT	aspartate transcarbamylase
A6E01_11365	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
A6E01_11370	ENOG4105KME	endoribonuclease L-psp
A6E01_11375	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
A6E01_11380	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A6E01_11385	ENOG4105VFK	BolA family
A6E01_11395	ENOG4105E3I	toluene tolerance
A6E01_11400	ENOG4107PE3	Mammalian cell entry related domain protein
A6E01_11405	ENOG4105CY3	ABC transporter, permease
A6E01_11410	ENOG4105DHJ	ABC, transporter
A6E01_11420	ENOG4105C2X	Arabinose 5-phosphate isomerase
A6E01_11425	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
A6E01_11440	ENOG4108IUZ	ABC transporter
A6E01_11445	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A6E01_11450	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
A6E01_11455	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
A6E01_11465	ENOG41080Z8	PHOSPHOCARRIER protein
A6E01_11470	ENOG4105CJW	magnesium transporter
A6E01_11475	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
A6E01_11480	ENOG4105N42	UPF0307 protein
A6E01_11485	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
A6E01_11495	ENOG4105QD6	exported protein
A6E01_11500	ENOG4105C03	ribonuclease
A6E01_11505	ENOG4108Z03	MAF-like protein
A6E01_11510	ENOG4105VQ7	Rod shape-determining protein MreD
A6E01_11515	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
A6E01_11520	ENOG4105DFF	Rod shape-determining protein mreb
A6E01_11555	ENOG4105KHS	type IV fimbrial pilin protein
A6E01_11570	ENOG4105D7Q	type ii secretion system
A6E01_11575	ENOG4107QHF	type ii secretion system protein e
A6E01_11590	ENOG4105GVR	general secretion pathway protein D
A6E01_11610	ENOG41062P1	Diguanylate cyclase phosphodiesterase
A6E01_11620	ENOG41086KC	Transcriptional regulator
A6E01_11625	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A6E01_11630	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A6E01_11640	ENOG4105C5R	Aminotransferase
A6E01_11645	ENOG4105CFH	Aspartokinase
A6E01_11655	ENOG4105EEQ	Na H antiporter
A6E01_11660	ENOG4105CVG	Homoserine O-transsuccinylase
A6E01_11755	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
A6E01_11765	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
A6E01_11785	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A6E01_11790	ENOG4107QP8	phosphohexose isomerase
A6E01_11795	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A6E01_11800	ENOG4105CDU	Replicative dna helicase
A6E01_11810	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
A6E01_11815	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
A6E01_11820	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
A6E01_11825	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
A6E01_11830	ENOG4108DBC	nitroreductase
A6E01_11835	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A6E01_11840	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
A6E01_11845	ENOG4105KPV	Transcriptional regulator
A6E01_11850	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
A6E01_11855	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A6E01_11865	ENOG4105EPW	hflc protein
A6E01_11870	ENOG4107QJR	hflk protein
A6E01_11875	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A6E01_11880	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
A6E01_11885	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
A6E01_11890	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
A6E01_11895	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A6E01_11900	ENOG4105K8N	protein family UPF0079, ATPase
A6E01_11905	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
A6E01_11955	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
A6E01_11960	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
A6E01_11965	ENOG4105DJ4	phosphatidylserine decarboxylase
A6E01_11975	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
A6E01_11980	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
A6E01_12000	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
A6E01_12010	ENOG4105E33	succinate dehydrogenase
A6E01_12015	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
A6E01_12020	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
A6E01_12025	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A6E01_12030	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
A6E01_12040	ENOG4105C5H	ABC transporter
A6E01_12045	ENOG4105DKW	ABC transporter
A6E01_12055	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A6E01_12060	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
A6E01_12070	ENOG4105D7W	serine acetyltransferase
A6E01_12075	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A6E01_12080	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
A6E01_12085	ENOG4107YZP	Rhodanese domain protein
A6E01_12090	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A6E01_12095	ENOG41063SB	peptidase
A6E01_12100	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
A6E01_12105	ENOG4105CBT	Fructose-1,6-bisphosphatase
A6E01_12120	ENOG4105CP7	Triose-phosphate isomerase
A6E01_12125	ENOG4105CTQ	phosphohexokinase
A6E01_12130	ENOG41076HS	cation diffusion facilitator family transporter
A6E01_12140	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A6E01_12145	ENOG4105E0F	Histidine kinase
A6E01_12150	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
A6E01_12155	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
A6E01_12160	ENOG4108RS6	transposase
A6E01_12165	ENOG4108IJ0	Aspartate ammonia-lyase
A6E01_12170	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
A6E01_12175	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
A6E01_12190	ENOG4107QN1	sodium solute
A6E01_12200	ENOG4105BZU	Histidine kinase
A6E01_12205	ENOG4105D8G	Major Facilitator superfamily
A6E01_12225	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
A6E01_12230	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
A6E01_12235	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A6E01_12240	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A6E01_12245	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A6E01_12250	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
A6E01_12275	ENOG4105C12	Phosphoribosylglycinamide synthetase
A6E01_12285	ENOG4108CIP	transcriptional regulator
A6E01_12305	ENOG4105R2J	Conserved Protein
A6E01_12310	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
A6E01_12320	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A6E01_12325	ENOG4105DSJ	YicC domain protein
A6E01_12340	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
A6E01_12345	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
A6E01_12350	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A6E01_12355	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
A6E01_12360	ENOG4105W5Q	DNA repair protein (RadC
A6E01_12370	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
A6E01_12375	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
A6E01_12380	ENOG4105D1S	lipid A biosynthesis
A6E01_12385	ENOG4105D1S	lipid A biosynthesis
A6E01_12390	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
A6E01_12395	ENOG4105E09	nadh pyrophosphatase
A6E01_12400	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
A6E01_12405	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A6E01_12410	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A6E01_12415	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
A6E01_12425	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A6E01_12430	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A6E01_12435	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
A6E01_12440	ENOG4105PM1	preprotein translocase subunit SecE
A6E01_12445	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A6E01_12470	ENOG4105CS9	pantothenic acid kinase
A6E01_12475	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A6E01_12480	ENOG4105D4A	Cell wall formation (By similarity)
A6E01_12490	ENOG4105JIM	Phosphatidylserine synthase
A6E01_12560	ENOG4105VFU	Rna-binding protein
A6E01_12565	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A6E01_12570	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
A6E01_12580	ENOG4105EJ2	Transcriptional regulator
A6E01_12585	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
A6E01_12590	ENOG4107R73	Mate efflux family protein
A6E01_12595	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A6E01_12600	ENOG41080IJ	Diacylglycerol kinase
A6E01_12605	ENOG4105E55	glycerol-3-phosphate acyltransferase
A6E01_12610	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
A6E01_12615	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
A6E01_12620	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
A6E01_12625	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
A6E01_12630	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A6E01_12635	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
A6E01_12640	ENOG4105CAK	Cell division ATP-binding protein ftsE
A6E01_12645	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A6E01_12650	ENOG4106H78	methyltransferase
A6E01_12685	ENOG4105MPD	Cytochrome
A6E01_12690	ENOG4105C4R	Atp-dependent dna helicase
A6E01_12695	ENOG4105Y7M	Transcriptional regulator, TetR family
A6E01_12700	ENOG410624X	efflux transporter, rnd family, mfp subunit
A6E01_12705	ENOG4105BZS	acriflavin resistance protein
A6E01_12710	ENOG4105W0Z	cytoplasmic protein
A6E01_12715	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
A6E01_12720	ENOG4105EMY	transcriptional regulator
A6E01_12780	ENOG4107QK7	reductase
A6E01_12785	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
A6E01_12790	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A6E01_12800	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
A6E01_12805	ENOG4105K63	Thioredoxin
A6E01_12810	ENOG4105C1J	atp-dependent rna helicase
A6E01_12815	ENOG4105C9X	ppx gppa phosphatase
A6E01_12820	ENOG4108I0Q	anthranilate phosphoribosyltransferase
A6E01_12825	ENOG4105EX9	Membrane
A6E01_12835	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A6E01_12840	ENOG4105FR1	rard protein
A6E01_12850	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A6E01_12855	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A6E01_12860	ENOG4105C4R	Atp-dependent dna helicase
A6E01_12870	ENOG4105E18	UPF0276 protein
A6E01_12895	ENOG4105D41	biosynthesis protein thiH
A6E01_12900	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
A6E01_12910	ENOG4105D06	uba thif-type nad fad binding protein
A6E01_12915	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
A6E01_12920	ENOG4105WMR	Protein CrcB homolog
A6E01_12960	ENOG4108RR8	protoporphyrinogen oxidase
A6E01_12965	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
A6E01_12970	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A6E01_12975	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A6E01_12985	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
A6E01_12990	ENOG4105G2Y	Transcriptional regulator
A6E01_12995	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
A6E01_13005	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
A6E01_13010	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
A6E01_13015	ENOG4105JKW	Valine--pyruvate aminotransferase
A6E01_13035	ENOG4108ZNX	Heat shock protein
A6E01_13040	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A6E01_13045	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
A6E01_13050	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A6E01_13075	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
A6E01_13085	ENOG4108JJA	ABC, transporter
A6E01_13105	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
A6E01_13130	ENOG4108NRW	Phospholipase, patatin family
A6E01_13140	ENOG4105D64	Mechanosensitive ion channel
A6E01_13165	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
A6E01_13170	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
A6E01_13180	ENOG4105E5M	Multidrug resistance protein D
A6E01_13185	ENOG4105EQ2	LysR family Transcriptional regulator
A6E01_13195	ENOG4108R86	Transcriptional regulator
A6E01_13200	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A6E01_13210	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
A6E01_13220	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A6E01_13225	ENOG4105BZ1	(ABC) transporter
A6E01_13240	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
A6E01_13250	ENOG4108IUM	Glycogen debranching enzyme
A6E01_13265	ENOG4108MDC	(LipO)protein
A6E01_13270	ENOG4108Q9C	Periplasmic Protein
A6E01_13275	ENOG4105E3R	(LipO)protein
A6E01_13300	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A6E01_13305	ENOG4105DWD	nucleoside recognition domain protein
A6E01_13315	ENOG4105EQR	Transposase IS116 IS110 IS902
A6E01_13320	ENOG4105D64	Mechanosensitive ion channel
A6E01_13325	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
A6E01_13335	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
A6E01_13360	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
A6E01_13365	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A6E01_13375	ENOG4105G6Z	alkaline phosphatase
A6E01_13380	ENOG4105CHR	reductase
A6E01_13390	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
A6E01_13395	ENOG4105C0A	alcohol dehydrogenase
A6E01_13405	ENOG4108Z4X	TRANSCRIPTIONal
A6E01_13415	ENOG4105D9U	N-acetyltransferase
A6E01_13425	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
A6E01_13430	ENOG4105CH6	catalase
A6E01_13450	ENOG4105EJC	lysr family transcriptional regulator
A6E01_13460	ENOG4105CBC	glutamate synthase
A6E01_13465	ENOG4105C3R	Methionine synthase
A6E01_13480	ENOG4105VV6	START domain-containing protein
A6E01_13490	ENOG4105EST	Metal Dependent Phosphohydrolase
A6E01_13500	ENOG4105E89	ABC transporter
A6E01_13505	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A6E01_13510	ENOG4105ETT	transcriptional Regulator, LysR family
A6E01_13560	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
A6E01_13605	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A6E01_13615	ENOG4105EIG	urea carboxylase-associated protein 1
A6E01_13640	ENOG4107QVM	von Willebrand factor, type A
A6E01_13655	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A6E01_13665	ENOG4107S6Z	Na H antiporter
A6E01_13670	ENOG4105CFQ	glutamine synthetase
A6E01_13675	ENOG4108Z86	Glutamine amidotransferase
A6E01_13680	ENOG4107VRI	Transcriptional regulator
A6E01_13685	ENOG4105C26	Dehydrogenase
A6E01_13690	ENOG4105CJP	fad dependent oxidoreductase
A6E01_13700	ENOG4105DWY	Agmatine deiminase
A6E01_13705	ENOG4105C26	Dehydrogenase
A6E01_13710	ENOG4108JPW	Aminotransferase
A6E01_13735	ENOG4107RGM	aldo keto reductase
A6E01_13740	ENOG4105JQN	Transcriptional regulator
A6E01_13755	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
A6E01_13760	ENOG4105DZC	cytosine deaminase
A6E01_13790	ENOG4105C2C	drug resistance transporter, Bcr CflA
A6E01_13805	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
A6E01_13825	ENOG4107QZF	nitrite reductase NADPH large subunit
A6E01_13835	ENOG4107R3J	Transporter
A6E01_13840	ENOG4105D9P	serine threonine protein kinase
A6E01_13865	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A6E01_13880	ENOG4105BZG	amino acid carrier protein
A6E01_13920	ENOG410600T	transposase
A6E01_13950	ENOG4105G2Y	Transcriptional regulator
A6E01_13965	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A6E01_13970	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A6E01_13990	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
A6E01_14000	ENOG4105G2Y	Transcriptional regulator
A6E01_14020	ENOG4105CG3	alpha amylase, catalytic region
A6E01_14025	ENOG4105VEQ	Cold shock protein
A6E01_14035	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A6E01_14045	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A6E01_14055	ENOG4105HEI	LysR family (Transcriptional regulator
A6E01_14060	ENOG4105R8A	Heat shock protein
A6E01_14080	ENOG4109015	Biopolymer transport protein exbD tolR
A6E01_14085	ENOG410822N	TonB family
A6E01_14105	ENOG4105CMM	transposase
A6E01_14120	ENOG4107RUE	extracellular solute-binding protein family 1
A6E01_14125	ENOG4105D38	putrescine abc transporter
A6E01_14130	ENOG4105F38	ABC transporter, permease
A6E01_14135	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A6E01_14140	ENOG4105DQS	Transcriptional regulator
A6E01_14185	ENOG4107SSZ	Phosphatase
A6E01_14200	ENOG41090WB	Transposase is3 is911
A6E01_14210	ENOG4105C7N	Xanthine uracil vitamin C permease
A6E01_14230	ENOG4107T9C	Alpha amylase catalytic region
A6E01_14240	ENOG4105EQR	Transposase IS116 IS110 IS902
A6E01_14245	ENOG4107RGM	aldo keto reductase
A6E01_14255	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
A6E01_14265	ENOG4105CQB	FAD linked oxidase domain protein
A6E01_14270	ENOG4105DMF	Dehydrogenase
A6E01_14275	ENOG4105DAA	L-lactate
A6E01_14280	ENOG4105CC0	LysR family Transcriptional regulator
A6E01_14285	ENOG4105HEI	LysR family (Transcriptional regulator
A6E01_14295	ENOG4105ES4	Nitrilase
A6E01_14315	ENOG4105EKQ	RNA-directed DNA polymerase
A6E01_14340	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
A6E01_14345	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
A6E01_14350	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
A6E01_14355	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6E01_14360	ENOG4105CQZ	Histidine kinase
A6E01_14365	ENOG41090HJ	UPF0265 protein
A6E01_14370	ENOG4108YXG	UPF0502 protein
A6E01_14375	ENOG41082IR	Excinuclease ABC C subunit domain protein
A6E01_14380	ENOG4108QGH	periplasmic
A6E01_14385	ENOG4105BZU	Histidine kinase
A6E01_14395	ENOG4105E1F	short-chain dehydrogenase reductase
A6E01_14400	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
A6E01_14405	ENOG41068P6	UPF0319 protein
A6E01_14410	ENOG4105EM2	membrane
A6E01_14415	ENOG41088T4	Helicase IV
A6E01_14430	ENOG4108Z5K	methylglyoxal synthase
A6E01_14435	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A6E01_14470	ENOG4105DHU	Bile acid
A6E01_14475	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A6E01_14480	ENOG4105EHG	Permease protein
A6E01_14490	ENOG4106GFD	transport protein
A6E01_14495	ENOG41090AP	transport protein
A6E01_14500	ENOG4105WQ5	TonB family
A6E01_14505	ENOG4105D4P	Coproporphyrinogen iii oxidase
A6E01_14510	ENOG41090JE	Utilization Protein
A6E01_14515	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
A6E01_14525	ENOG4105BZ1	(ABC) transporter
A6E01_14550	ENOG4105CMM	transposase
A6E01_14570	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A6E01_14580	ENOG4105BZU	Histidine kinase
A6E01_14585	ENOG4105WH1	Two component transcriptional regulator luxr family
A6E01_14590	ENOG4105WKW	Pfam:DUF1458
A6E01_14600	ENOG4105D06	uba thif-type nad fad binding protein
A6E01_14605	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A6E01_14610	ENOG4105EUJ	GTP cyclohydrolase i
A6E01_14620	ENOG4105CKI	cobalamin synthesis protein
A6E01_14630	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
A6E01_14635	ENOG410600T	transposase
A6E01_14640	ENOG4105EMU	Dehydrogenase
A6E01_14645	ENOG4105ID8	Transcriptional regulator, ARAC family
A6E01_14650	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
A6E01_14655	ENOG4105C1J	atp-dependent rna helicase
A6E01_14675	ENOG4106HK8	GPR1 FUN34 yaaH family protein
A6E01_14680	ENOG4107R7I	amino acid
A6E01_14690	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
A6E01_14700	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A6E01_14705	ENOG4105DVI	reductase, NrfD
A6E01_14710	ENOG4105DA4	cytochrome c-type biogenesis protein
A6E01_14715	ENOG4108DMF	Cytochrome C biogenesis protein
A6E01_14725	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
A6E01_14730	ENOG4105ENH	Sulfatase
A6E01_14735	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
A6E01_14740	ENOG4105BZS	acriflavin resistance protein
A6E01_14745	ENOG41061MV	Arylsulfatase
A6E01_14755	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A6E01_14785	ENOG41064T2	transcriptional regulator, lysR family
A6E01_14795	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
A6E01_14810	ENOG4105C4X	radical SAM domain protein
A6E01_14825	ENOG4105F27	Major Facilitator
A6E01_14830	ENOG4105EMU	Dehydrogenase
A6E01_14840	ENOG4105CC0	LysR family Transcriptional regulator
A6E01_14870	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A6E01_14875	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A6E01_14880	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A6E01_14895	ENOG4108RG0	uracil-dna glycosylase
A6E01_14915	ENOG4106YYS	transcriptional regulatory protein
A6E01_14920	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
A6E01_14925	ENOG4105DRP	amino acid AbC transporter
A6E01_14930	ENOG4105E89	ABC transporter
A6E01_14935	ENOG4105E5Q	amino acid AbC transporter
A6E01_14940	ENOG4105CDA	abc transporter atp-binding protein
A6E01_14945	ENOG4105G2Y	Transcriptional regulator
A6E01_14955	ENOG4105CFU	surface antigen
A6E01_14960	ENOG4105T0Z	Conserved Protein
A6E01_14975	ENOG4107RZC	phospholipase d
A6E01_14980	ENOG4105EBR	Carboxylesterase
A6E01_15005	ENOG4108UHU	Aldolase
A6E01_15010	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
A6E01_15015	ENOG4105M5J	Cupin 2, conserved barrel domain protein
A6E01_15020	ENOG4105EY3	heparinase II III family protein
A6E01_15025	ENOG4105EY3	heparinase II III family protein
A6E01_15040	ENOG4107EJG	GntR family transcriptional regulator
A6E01_15045	ENOG4107EJG	GntR family transcriptional regulator
A6E01_15050	ENOG41080XP	Cbs domain
A6E01_15055	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
A6E01_15110	ENOG410901P	UPF0249 protein
A6E01_15115	ENOG4107RJ1	sodium solute
A6E01_15125	ENOG4107RJ1	sodium solute
A6E01_15145	ENOG4108RCM	Nitroreductase
A6E01_15150	ENOG4105EQR	Transposase IS116 IS110 IS902
A6E01_15160	ENOG4105EVZ	LysR family transcriptional regulator
A6E01_15195	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A6E01_15200	ENOG4105BZU	Histidine kinase
A6E01_15230	ENOG4105CV8	reductase
A6E01_15245	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
A6E01_15250	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
A6E01_15305	ENOG4107RZC	phospholipase d
A6E01_15325	ENOG4108YI8	ABC transporter
A6E01_15330	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
A6E01_15335	ENOG4107Z6I	Thiamine biosynthesis protein
A6E01_15340	ENOG4107Z6I	Thiamine biosynthesis protein
A6E01_15345	ENOG4105ETU	transcriptional activator (TenA
A6E01_15350	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
A6E01_15355	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
A6E01_15370	ENOG4105C82	Malate synthase
A6E01_15375	ENOG4107RET	Isocitrate lyase
A6E01_15385	ENOG4107RGH	Aldehyde dehydrogenase
A6E01_15395	ENOG4108K3A	Glutathione S-transferase
A6E01_15400	ENOG4105WQ3	Rna-binding protein
A6E01_15405	ENOG4108I6A	alcohol dehydrogenase
A6E01_15415	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
A6E01_15420	ENOG4105C1J	atp-dependent rna helicase
A6E01_15425	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
A6E01_15430	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A6E01_15440	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A6E01_15445	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
A6E01_15455	ENOG4105G2Y	Transcriptional regulator
A6E01_15465	ENOG4105N1F	Hnh endonuclease
A6E01_15470	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
A6E01_15495	ENOG4107QZF	nitrite reductase NADPH large subunit
A6E01_15500	ENOG4105WZK	nitrite reductase NADPH small subunit
A6E01_15505	ENOG4105TMB	Formate nitrite transporter
A6E01_15510	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A6E01_15535	ENOG4105CND	Glycosyl transferase, family 2
A6E01_15540	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A6E01_15580	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A6E01_15610	ENOG410600T	transposase
A6E01_15620	ENOG4105XEA	Tetr family transcriptional regulator
A6E01_15660	ENOG4105C2C	drug resistance transporter, Bcr CflA
A6E01_15675	ENOG4108IGT	Dipeptidase
A6E01_15695	ENOG4105C5Y	PTS System
A6E01_15700	ENOG4105D7K	pfkb domain protein
A6E01_15705	ENOG4108HKT	sucrose-6-phosphate hydrolase
A6E01_15720	ENOG4105EBR	Carboxylesterase
A6E01_15725	ENOG4105CR8	Transcriptional regulator
A6E01_15730	ENOG4105FDK	ABC transporter
A6E01_15755	ENOG4105EKQ	RNA-directed DNA polymerase
A6E01_15770	ENOG4105DHQ	Histidine kinase
A6E01_15810	ENOG4108UMN	azlc family
A6E01_15835	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
A6E01_15845	ENOG4107QI1	Mate efflux family protein
A6E01_15850	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
A6E01_15875	ENOG4108UW5	maltose o-acetyltransferase
A6E01_15925	ENOG4107XU6	Glycosyl transferase (Group 1
A6E01_15930	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6E01_15955	ENOG41082AN	stage II sporulation protein
A6E01_15975	ENOG4105CMM	transposase
A6E01_15990	ENOG4107VXZ	Hydrolase
A6E01_15995	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A6E01_16005	ENOG4107RE1	Inosine-guanosine kinase
A6E01_16020	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A6E01_16030	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
A6E01_16045	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A6E01_16055	ENOG4107RV5	Glycosyl hydrolase family 3 N-terminal domain protein
A6E01_16065	ENOG41080HT	Transcriptional regulator, arsr family
A6E01_16085	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
A6E01_16090	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
A6E01_16095	ENOG4105CGF	Aromatic amino acid aminotransferase
A6E01_16100	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A6E01_16105	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
A6E01_16110	ENOG4105E0C	molybdate abc transporter
A6E01_16115	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
A6E01_16135	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A6E01_16140	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A6E01_16175	ENOG4105C2I	pirin domain protein
A6E01_16180	ENOG4105EQ1	Transcriptional regulator
A6E01_16190	ENOG4105C7N	Xanthine uracil vitamin C permease
A6E01_16195	ENOG4108ZJT	translation initiation factor, Sui1
A6E01_16205	ENOG4105CPF	Cell wall formation (By similarity)
A6E01_16215	ENOG4105CD5	CoA-binding domain protein
A6E01_16220	ENOG4105CWB	LysR family transcriptional Regulator
A6E01_16225	ENOG4105CMR	udp-glucose 4-epimerase
A6E01_16235	ENOG4105P4J	Allophanate hydrolase, subunit 1
A6E01_16245	ENOG4105CV6	ABC transporter, permease
A6E01_16250	ENOG4108I0Y	(ABC) transporter
A6E01_16260	ENOG4105RKW	reductase (By
A6E01_16265	ENOG4105BZU	Histidine kinase
A6E01_16280	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
A6E01_16285	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
A6E01_16290	ENOG4108YZ4	nudix hydrolase
A6E01_16300	ENOG4105EQR	Transposase IS116 IS110 IS902
A6E01_16305	ENOG4105C1J	atp-dependent rna helicase
A6E01_16320	ENOG4105UQX	Mate efflux family protein
A6E01_16335	ENOG4105EYK	Phosphatidylglycerophosphatase B
A6E01_16340	ENOG4105DGU	Histone deacetylase
A6E01_16345	ENOG4105C1J	atp-dependent rna helicase
A6E01_16350	ENOG4105VXR	cytoplasmic protein
A6E01_16355	ENOG4105E43	Extracellular solute-binding protein, family 5
A6E01_16360	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
A6E01_16365	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
A6E01_16375	ENOG4108JQ5	ABC transporter
A6E01_16380	ENOG4105CNG	UPF0061 protein
A6E01_16395	ENOG4105EFX	secretion protein, HlyD family
A6E01_16410	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
A6E01_16420	ENOG4105KA0	thioesterase Superfamily protein
A6E01_16430	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
A6E01_16435	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
A6E01_16445	ENOG4107QX8	SPFH domain, Band 7 family protein
A6E01_16460	ENOG4107TE5	Lipid kinase
A6E01_16475	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A6E01_16495	ENOG4105C44	Serine transporter
A6E01_16500	ENOG4105EJQ	L-serine dehydratase
A6E01_16510	ENOG4105F87	Dehydratase
A6E01_16520	ENOG4105CGH	5'-nucleotidase
A6E01_16525	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
A6E01_16535	ENOG4108YYC	ycei family
A6E01_16540	ENOG4105DS1	cytochrome b561
A6E01_16560	ENOG4105D6U	Sodium Glutamate Symporter
A6E01_16565	ENOG4105C5H	ABC transporter
A6E01_16575	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
A6E01_16580	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
A6E01_16585	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
A6E01_16595	ENOG4105CYM	Glutathione S-transferase
A6E01_16600	ENOG4105VRT	cytoplasmic protein
A6E01_16625	ENOG4105XDF	Protein of unknown function (DUF1272)
A6E01_16635	ENOG4105CPQ	Dehydrogenase
A6E01_16640	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A6E01_16645	ENOG4105EXG	Transcriptional regulator
A6E01_16650	ENOG4105CS2	ec 3.2.1.21
A6E01_16690	ENOG4108UKZ	OsmC family
A6E01_16700	ENOG4108VWS	Yaeq family
A6E01_16710	ENOG4105IPI	Membrane
A6E01_16715	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
A6E01_16745	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
A6E01_16750	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
A6E01_16760	ENOG4105EKE	dihydroorotase
A6E01_16765	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A6E01_16770	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
A6E01_16780	ENOG4105CVA	phosphate
A6E01_16795	ENOG4105DAN	ATP-dependent protease
A6E01_16820	ENOG4105CNT	hydrolase family 2
A6E01_16830	ENOG4105EQR	Transposase IS116 IS110 IS902
A6E01_16835	ENOG4105CIS	alcohol dehydrogenase
A6E01_16840	ENOG4107RSM	transcriptional regulator
A6E01_16845	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
A6E01_16850	ENOG41064T2	transcriptional regulator, lysR family
A6E01_16855	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
A6E01_16860	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
A6E01_16865	ENOG4105DE4	1-phosphofructokinase
A6E01_16870	ENOG4105DM4	PTS System
A6E01_16900	ENOG4105C1J	atp-dependent rna helicase
A6E01_16910	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A6E01_16915	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A6E01_16945	ENOG4105DR5	peptidase
A6E01_16965	ENOG4105EG2	ABC transporter, permease
A6E01_16970	ENOG4105D56	permease protein
A6E01_16975	ENOG4107FKK	extracellular solute-binding protein family 1
A6E01_16980	ENOG4108IJ9	(ABC) transporter
A6E01_17005	ENOG41086KC	Transcriptional regulator
A6E01_17015	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A6E01_17020	ENOG4105E2Z	phosphate ABC transporter (Permease
A6E01_17025	ENOG4105C8U	phosphate abc transporter
A6E01_17030	ENOG4107S17	Phosphate-binding protein
A6E01_17045	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
A6E01_17050	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
A6E01_17055	ENOG4107SEY	Conserved Protein
A6E01_17070	ENOG4105KK7	inner membrane protein YiaW
A6E01_17075	ENOG4105EFX	secretion protein, HlyD family
A6E01_17085	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A6E01_17090	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
A6E01_17095	ENOG4105DN9	Na H antiporter
A6E01_17100	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
A6E01_17125	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
A6E01_17145	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A6E01_17150	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
A6E01_17160	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A6E01_17165	ENOG4105EGI	Transcriptional regulator
A6E01_17205	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
A6E01_17210	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
A6E01_17215	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
A6E01_17220	ENOG41061ZR	Transcriptional regulator
A6E01_17235	ENOG4105D3Q	Sugar transferase
A6E01_17240	ENOG4108RYC	glycosyltransferase
A6E01_17245	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A6E01_17250	ENOG4108RJ9	Glycosyl transferase, family 2
A6E01_17280	ENOG4105CMM	transposase
A6E01_17285	ENOG4105CAF	HipA N-terminal domain protein
A6E01_17290	ENOG4108RS6	transposase
A6E01_17305	ENOG41061P8	Persistence to inhibition of murein or DNA biosynthesis regulatory protein
A6E01_17325	ENOG4105E7D	Protein of unknown function (DUF3375)
A6E01_17390	ENOG4108FPN	Integrase
A6E01_17455	ENOG4105CFU	surface antigen
A6E01_17480	ENOG4105ESV	Glycosyl transferase, family 4
A6E01_17485	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A6E01_17490	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
A6E01_17500	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
A6E01_17510	ENOG4105C11	sulfate adenylyltransferase), subunit 2
A6E01_17535	ENOG4105CGN	Glycosyl transferase (Group 1
A6E01_17560	ENOG4105K64	Glycosyl transferase, family 2
A6E01_17570	ENOG4105D75	Capsular exopolysaccharide family
A6E01_17585	ENOG4105DAY	polysaccharide export protein
A6E01_17590	ENOG4105C11	sulfate adenylyltransferase), subunit 2
A6E01_17600	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
A6E01_17610	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
A6E01_17685	ENOG4105BZ1	(ABC) transporter
A6E01_17700	ENOG4105CJP	fad dependent oxidoreductase
A6E01_17710	ENOG4107RCV	ABC transporter, permease
A6E01_17715	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A6E01_17735	ENOG4105EQR	Transposase IS116 IS110 IS902
A6E01_17745	ENOG4107STF	Involved in phosphonate degradation (By similarity)
A6E01_17750	ENOG4105C8Y	Acetylornithine aminotransferase
A6E01_17755	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
A6E01_17790	ENOG4105C5R	Aminotransferase
A6E01_17795	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A6E01_17805	ENOG4105DHU	Bile acid
A6E01_17810	ENOG4106G6Q	Transcriptional regulator
A6E01_17815	ENOG4105CDA	abc transporter atp-binding protein
A6E01_17820	ENOG4105E5Q	amino acid AbC transporter
A6E01_17830	ENOG4105F87	Dehydratase
A6E01_17835	ENOG4105EQR	Transposase IS116 IS110 IS902
A6E01_17840	ENOG4105E09	nadh pyrophosphatase
A6E01_17845	ENOG4105EJQ	L-serine dehydratase
A6E01_17850	ENOG4105CYW	agmatinase
A6E01_17855	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
A6E01_17860	ENOG4105CKU	formyltetrahydrofolate synthetase
A6E01_17880	ENOG4105CT4	transporter
A6E01_17895	ENOG4105EUZ	Beta-lactamase domain protein
A6E01_17900	ENOG41064T2	transcriptional regulator, lysR family
A6E01_17905	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A6E01_17910	ENOG4105C26	Dehydrogenase
A6E01_17925	ENOG4105C26	Dehydrogenase
A6E01_17940	ENOG4105D38	putrescine abc transporter
A6E01_17945	ENOG4105F38	ABC transporter, permease
A6E01_17950	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A6E01_17955	ENOG4107RUE	extracellular solute-binding protein family 1
A6E01_17960	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A6E01_17965	ENOG4105CFQ	glutamine synthetase
A6E01_17970	ENOG4105CFQ	glutamine synthetase
A6E01_17975	ENOG4105CJP	fad dependent oxidoreductase
A6E01_17985	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
A6E01_17990	ENOG4105DFW	ABC transporter
A6E01_17995	ENOG4105C2J	ABC transporter
A6E01_18000	ENOG4107RNG	ABC transporter
A6E01_18005	ENOG4108M3R	transcriptional activator CadC
A6E01_18020	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A6E01_18025	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A6E01_18075	ENOG4105CC0	LysR family Transcriptional regulator
A6E01_18080	ENOG4105E2V	Glycosyltransferase 36
A6E01_18085	ENOG4105CT4	transporter
A6E01_18090	ENOG4108R6W	Transcriptional regulator, ARAC family
A6E01_18105	ENOG4105CHR	reductase
A6E01_18110	ENOG410600T	transposase
A6E01_18115	ENOG4105C2I	pirin domain protein
A6E01_18120	ENOG4108VGI	doxx family
A6E01_18125	ENOG4105EQ1	Transcriptional regulator
A6E01_18135	ENOG4105CHF	Glutathione S-transferase
A6E01_18150	ENOG4105EMU	Dehydrogenase
A6E01_18155	ENOG410600T	transposase
A6E01_18160	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
A6E01_18170	ENOG4105ETE	Transcriptional regulator (LacI family
A6E01_18190	ENOG4105CR8	Transcriptional regulator
A6E01_18235	ENOG4105K4U	addiction module toxin, RelE StbE family
A6E01_18245	ENOG4105C1J	atp-dependent rna helicase
A6E01_18250	ENOG4105K56	Transcriptional regulator
A6E01_18255	ENOG4108ZHJ	Organic hydroperoxide resistance protein
A6E01_18265	ENOG4105CI1	PTS System
A6E01_18270	ENOG4105ETT	transcriptional Regulator, LysR family
A6E01_18275	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
A6E01_18280	ENOG4105W08	virulence gene repressor rsal
A6E01_18305	ENOG4105D3G	Pseudouridine synthase
A6E01_18355	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A6E01_18360	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
A6E01_18365	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A6E01_18370	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A6E01_18375	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A6E01_18380	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
A6E01_18385	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A6E01_18390	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
A6E01_18400	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
A6E01_18405	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A6E01_18415	ENOG4105KME	endoribonuclease L-psp
A6E01_18420	ENOG4105WWK	YheO domain protein
A6E01_18450	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A6E01_18460	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A6E01_18475	ENOG4105D3W	isochorismatase
A6E01_18480	ENOG4107RB3	L-asparaginase
A6E01_18525	ENOG4108M6U	Universal stress protein A
A6E01_18535	ENOG4105D0C	transport protein
A6E01_18540	ENOG4105CEB	Aspartate aminotransferase
A6E01_18545	ENOG4105D6U	Sodium Glutamate Symporter
A6E01_18565	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
A6E01_18595	ENOG4105DUM	transcriptional regulator, lysR family
A6E01_18600	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
A6E01_18605	ENOG4105C2J	ABC transporter
A6E01_18610	ENOG4105CNN	ABC, transporter
A6E01_18615	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
A6E01_18620	ENOG4108RVA	ribokinase
A6E01_18625	ENOG4105ETE	Transcriptional regulator (LacI family
A6E01_18635	ENOG4107ZYR	domain protein
A6E01_18640	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
A6E01_18675	ENOG4107W52	maltose operon periplasmic protein
A6E01_18680	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
A6E01_18685	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
A6E01_18690	ENOG4108JQ7	(ABC) transporter
A6E01_18700	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A6E01_18725	ENOG4105ETE	Transcriptional regulator (LacI family
A6E01_18730	ENOG4108BGM	Quinol dehydrogenase periplasmic component
A6E01_18735	ENOG4105GXZ	Ferredoxin-type protein NapH
A6E01_18745	ENOG4105C19	ABC transporter
A6E01_18775	ENOG4107V40	secretion protein, HlyD family
A6E01_18795	ENOG4105EP9	oxidoreductase
A6E01_18800	ENOG4105BZU	Histidine kinase
A6E01_18815	ENOG4105DR5	peptidase
A6E01_18820	ENOG4108YYI	Protein of unknown function (DUF2810)
A6E01_18825	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A6E01_18835	ENOG4105CDY	transcriptional regulatory protein
A6E01_18845	ENOG4107PU6	Membrane
A6E01_18885	ENOG4105D00	flagellar biosynthetic protein flhB
A6E01_18890	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
A6E01_18895	ENOG4105VS8	Flagellar biosynthetic protein fliq
A6E01_18900	ENOG4105CN7	Flagellar biosynthetic protein FliP
A6E01_18905	ENOG4105DD5	Flagellar motor switch protein
A6E01_18915	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
A6E01_18920	ENOG4108ZC9	flagellar basal-body rod protein flgc
A6E01_18930	ENOG4105BZE	flagellar hook protein, FlgE
A6E01_18935	ENOG4108KPB	Flagellar basal-body rod protein FlgF
A6E01_18940	ENOG4105CGA	flagellar basal-body rod protein FlgG
A6E01_18945	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
A6E01_18950	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
A6E01_18965	ENOG4105DTJ	flagellar hook-associated protein
A6E01_18970	ENOG4105UYK	outer membrane protein a
A6E01_18975	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
A6E01_18980	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
A6E01_19055	ENOG4105I03	Flagellin
A6E01_19060	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
A6E01_19095	ENOG4107RD7	Flagellar Motor Protein, MotA
A6E01_19170	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A6E01_19200	ENOG4107QHF	type ii secretion system protein e
A6E01_19205	ENOG4105IPI	Membrane
A6E01_19455	ENOG4105EHV	domain protein
A6E01_19525	ENOG4105CAF	HipA N-terminal domain protein
A6E01_19555	ENOG4105MEW	serine threonine protein phosphatase
A6E01_19570	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A6E01_19580	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A6E01_19600	ENOG4105W5Q	DNA repair protein (RadC
A6E01_19640	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
A6E01_19725	ENOG4105DH7	May be involved in recombination (By similarity)
A6E01_19735	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
A6E01_19825	ENOG4105FA0	parb-like partition protein
A6E01_19910	ENOG4105DK2	UPF0207 protein
A6E01_20185	ENOG410839U	amino acid
A6E01_20265	ENOG4107QX8	SPFH domain, Band 7 family protein
A6E01_20380	ENOG4106V8H	Nucleoid-associated protein
A6E01_20420	ENOG4105DR5	peptidase
A6E01_20625	ENOG4105CJB	Exodeoxyribonuclease I
A6E01_20645	ENOG4105D64	Mechanosensitive ion channel
A6E01_20705	ENOG4108UUM	single-stranded DNA-binding protein
A6E01_20725	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
A6E01_20795	ENOG4108IAB	Phoh family