locus-tag	class	description
Vc3S01_0001	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Vc3S01_0014	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Vc3S01_0021	COG4974	Belongs to the 'phage' integrase family
Vc3S01_0026	COG1126	abc transporter atp-binding protein
Vc3S01_0030	COG0592	DNA-directed DNA polymerase activity
Vc3S01_0032	COG0187	DNA topoisomerase II activity
Vc3S01_0033	COG0071	Belongs to the small heat shock protein (HSP20) family
Vc3S01_0034	COG3977	Valine--pyruvate aminotransferase
Vc3S01_0037	COG2119	membrane
Vc3S01_0040	COG0425	Belongs to the sulfur carrier protein TusA family
Vc3S01_0043	COG0604	alcohol dehydrogenase
Vc3S01_0044	COG0183	Belongs to the thiolase family
Vc3S01_0046	COG1739	Uncharacterized protein family UPF0029
Vc3S01_0047	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vc3S01_0051	COG2132	Multicopper oxidase
Vc3S01_0055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Vc3S01_0056	COG2104	thiamine diphosphate biosynthetic process
Vc3S01_0059	COG0006	proline dipeptidase activity
Vc3S01_0059	COG0006	proline dipeptidase activity
Vc3S01_0061	COG2814	Major facilitator Superfamily
Vc3S01_0065	COG3220	belongs to the UPF0276 family
Vc3S01_0067	COG0210	DNA helicase
Vc3S01_0068	COG0405	Gamma-glutamyltransferase
Vc3S01_0069	COG1280	lysine exporter protein (LysE YggA)
Vc3S01_0073	COG2962	Rard protein
Vc3S01_0074	COG0514	ATP-dependent DNA helicase (RecQ)
Vc3S01_0076	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Vc3S01_0079	COG3118	belongs to the thioredoxin family
Vc3S01_0080	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Vc3S01_0082	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Vc3S01_0083	COG0633	Ferredoxin
Vc3S01_0087	COG3071	HemY protein
Vc3S01_0088	COG2959	enzyme of heme biosynthesis
Vc3S01_0089	COG1587	Uroporphyrinogen-III synthase
Vc3S01_0091	COG3072	Adenylate cyclase
Vc3S01_0094	COG0019	diaminopimelate decarboxylase activity
Vc3S01_0098	COG1011	Hydrolase
Vc3S01_0099	COG2200	EAL domain
Vc3S01_0099	COG2199	diguanylate cyclase activity
Vc3S01_0099	COG3287	FIST C domain
Vc3S01_0103	COG0561	phosphatase activity
Vc3S01_0104	COG2267	carboxylic ester hydrolase activity
Vc3S01_0105	COG1280	lysine exporter protein (LysE YggA)
Vc3S01_0106	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Vc3S01_0107	COG0640	Transcriptional regulator
Vc3S01_0108	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Vc3S01_0119	COG2095	MarC family integral membrane protein
Vc3S01_0121	COG0742	ribosomal rna small subunit methyltransferase
Vc3S01_0122	COG0552	protein localization to endoplasmic reticulum
Vc3S01_0123	COG2884	Cell division ATP-binding protein ftsE
Vc3S01_0124	COG2177	Part of the ABC transporter FtsEX involved in
Vc3S01_0127	COG0705	Rhomboid family
Vc3S01_0128	COG1580	Controls the rotational direction of flagella during chemotaxis
Vc3S01_0129	COG3161	chorismate lyase activity
Vc3S01_0131	COG2937	Belongs to the GPAT DAPAT family
Vc3S01_0134	COG0534	Mate efflux family protein
Vc3S01_0149	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Vc3S01_0151	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Vc3S01_0155	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Vc3S01_0156	COG0250	Participates in transcription elongation, termination and antitermination
Vc3S01_0159	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Vc3S01_0165	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
Vc3S01_0166	COG2816	NAD+ diphosphatase activity
Vc3S01_0170	COG1573	uracil-dna glycosylase
Vc3S01_0172	COG3068	Protein conserved in bacteria
Vc3S01_0173	COG1253	flavin adenine dinucleotide binding
Vc3S01_0176	COG0151	Belongs to the GarS family
Vc3S01_0179	COG0789	Transcriptional regulator
Vc3S01_0180	COG3710	Transcriptional regulator
Vc3S01_0181	COG0531	amino acid
Vc3S01_0182	COG1982	Orn Lys Arg decarboxylase major
Vc3S01_0188	COG3706	GGDEF domain
Vc3S01_0189	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
Vc3S01_0190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Vc3S01_0192	COG0439	Biotin carboxylase
Vc3S01_0193	COG0511	ligase activity, forming carbon-carbon bonds
Vc3S01_0194	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Vc3S01_0195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Vc3S01_0198	COG2814	Major facilitator Superfamily
Vc3S01_0199	COG0784	Response regulator, receiver
Vc3S01_0199	COG2205	protein histidine kinase activity
Vc3S01_0199	COG2198	Histidine kinase
Vc3S01_0203	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Vc3S01_0205	COG2095	MarC family integral membrane protein
Vc3S01_0207	COG4232	protein-disulfide reductase activity
Vc3S01_0208	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Vc3S01_0209	COG1027	Aspartate ammonia-lyase
Vc3S01_0210	COG3030	protein affecting phage T7 exclusion by the F plasmid
Vc3S01_0211	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Vc3S01_0213	COG2205	protein histidine kinase activity
Vc3S01_0214	COG0745	RESPONSE REGULATOR receiver
Vc3S01_0218	COG0534	Mate efflux family protein
Vc3S01_0219	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Vc3S01_0223	COG1509	lysine 2,3-aminomutase activity
Vc3S01_0229	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Vc3S01_0230	COG1053	succinate dehydrogenase
Vc3S01_0235	COG4942	peptidase
Vc3S01_0236	COG1045	serine acetyltransferase
Vc3S01_0239	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Vc3S01_0240	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Vc3S01_0242	COG0840	transmembrane signaling receptor activity
Vc3S01_0243	COG0471	metal ion transport
Vc3S01_0245	COG1162	GTPase activity
Vc3S01_0247	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Vc3S01_0248	COG0802	atpase or kinase
Vc3S01_0249	COG0860	N-Acetylmuramoyl-L-alanine amidase
Vc3S01_0250	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Vc3S01_0253	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Vc3S01_0254	COG0330	HflC and HflK could
Vc3S01_0255	COG0330	HflC and HflK could
Vc3S01_0256	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
Vc3S01_0257	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Vc3S01_0258	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
Vc3S01_0259	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Vc3S01_0259	COG1017	nitric oxide dioxygenase activity
Vc3S01_0261	COG0557	exoribonuclease II activity
Vc3S01_0262	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Vc3S01_0263	COG0546	phosphoglycolate phosphatase activity
Vc3S01_0267	COG0512	Glutamine amidotransferase of anthranilate synthase
Vc3S01_0269	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Vc3S01_0273	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Vc3S01_0274	COG3954	Phosphoribulokinase
Vc3S01_0276	COG0429	hydrolase of the alpha beta-hydrolase fold
Vc3S01_0278	COG0488	(ABC) transporter
Vc3S01_0279	COG2249	NAD(P)H dehydrogenase (quinone) activity
Vc3S01_0282	COG1047	Peptidyl-prolyl cis-trans
Vc3S01_0284	COG1446	asparaginase
Vc3S01_0287	COG0545	Peptidyl-prolyl cis-trans isomerase
Vc3S01_0288	COG2964	Protein conserved in bacteria
Vc3S01_0289	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
Vc3S01_0290	COG2923	Belongs to the DsrF TusC family
Vc3S01_0291	COG2168	tRNA wobble position uridine thiolation
Vc3S01_0294	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Vc3S01_0296	COG2906	2 iron, 2 sulfur cluster binding
Vc3S01_0298	COG0281	malic enzyme
Vc3S01_0300	COG0626	cystathionine gamma-synthase activity
Vc3S01_0301	COG0527	aspartate kinase activity
Vc3S01_0301	COG0460	homoserine dehydrogenase
Vc3S01_0302	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Vc3S01_0304	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Vc3S01_0306	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Vc3S01_0309	COG0165	Argininosuccinate lyase
Vc3S01_0309	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Vc3S01_0312	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vc3S01_0313	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Vc3S01_0313	COG0678	peroxiredoxin activity
Vc3S01_0315	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Vc3S01_0324	COG0338	D12 class N6 adenine-specific DNA methyltransferase
Vc3S01_0325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Vc3S01_0330	COG0305	Participates in initiation and elongation during chromosome replication
Vc3S01_0331	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Vc3S01_0333	COG0432	Pfam Uncharacterised protein family UPF0047
Vc3S01_0336	COG0735	belongs to the Fur family
Vc3S01_0358	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Vc3S01_0362	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Vc3S01_0371	COG0646	methionine synthase
Vc3S01_0371	COG1410	methionine synthase
Vc3S01_0372	COG0527	aspartate kinase activity
Vc3S01_0373	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Vc3S01_0375	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Vc3S01_0378	COG0629	single-stranded DNA binding
Vc3S01_0379	COG2199	diguanylate cyclase activity
Vc3S01_0379	COG2200	EAL domain
Vc3S01_0384	COG3409	Peptidoglycan-binding domain 1 protein
Vc3S01_0384	COG3267	Type II secretory pathway component ExeA
Vc3S01_0386	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vc3S01_0387	COG1459	type II secretion system
Vc3S01_0396	COG1077	Cell shape determining protein MreB Mrl
Vc3S01_0397	COG1792	Involved in formation and maintenance of cell shape
Vc3S01_0398	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
Vc3S01_0399	COG0424	maF-like protein
Vc3S01_0400	COG1530	ribonuclease E activity
Vc3S01_0401	COG3164	Protein of unknown function
Vc3S01_0402	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Vc3S01_0403	COG0312	modulator of DNA gyrase
Vc3S01_0404	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Vc3S01_0407	COG0564	pseudouridine synthase activity
Vc3S01_0408	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Vc3S01_0410	COG0312	modulator of DNA gyrase
Vc3S01_0411	COG2239	Acts as a magnesium transporter
Vc3S01_0412	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vc3S01_0414	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vc3S01_0415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Vc3S01_0417	COG1137	ATPase activity
Vc3S01_0418	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
Vc3S01_0420	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Vc3S01_0420	COG0517	IMP dehydrogenase activity
Vc3S01_0422	COG1127	ABC transporter
Vc3S01_0423	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Vc3S01_0424	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Vc3S01_0425	COG2854	intermembrane phospholipid transfer
Vc3S01_0427	COG5007	Belongs to the BolA IbaG family
Vc3S01_0429	COG0204	Acyl-transferase
Vc3S01_0430	COG0251	oxidation-reduction process
Vc3S01_0438	COG0456	acetyltransferase
Vc3S01_0440	COG0525	valine-tRNA ligase activity
Vc3S01_0441	COG2927	DNA polymerase III (CHI subunit)
Vc3S01_0443	COG0795	lipopolysaccharide-transporting ATPase activity
Vc3S01_0444	COG0795	lipopolysaccharide-transporting ATPase activity
Vc3S01_0446	COG1028	Short-chain dehydrogenase reductase Sdr
Vc3S01_0448	COG0726	polysaccharide deacetylase
Vc3S01_0451	COG1447	Phosphotransferase system cellobiose-specific component IIA
Vc3S01_0452	COG1486	melibiose metabolic process
Vc3S01_0458	COG1012	belongs to the aldehyde dehydrogenase family
Vc3S01_0468	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Vc3S01_0469	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Vc3S01_0472	COG0762	integral membrane protein
Vc3S01_0473	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Vc3S01_0474	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Vc3S01_0477	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Vc3S01_0478	COG1678	Uncharacterized ACR, COG1678
Vc3S01_0479	COG0189	ligase activity
Vc3S01_0480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Vc3S01_0481	COG2356	endonuclease I
Vc3S01_0485	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Vc3S01_0488	COG0191	fructose-bisphosphate aldolase activity
Vc3S01_0490	COG0668	transmembrane transport
Vc3S01_0493	COG0583	DNA-binding transcription factor activity
Vc3S01_0494	COG2968	Membrane
Vc3S01_0495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vc3S01_0497	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Vc3S01_0498	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
Vc3S01_0500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vc3S01_0501	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vc3S01_0505	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
Vc3S01_0507	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Vc3S01_0508	COG1595	DNA-templated transcription, initiation
Vc3S01_0511	COG3086	response to oxidative stress
Vc3S01_0513	COG0681	Belongs to the peptidase S26 family
Vc3S01_0515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Vc3S01_0516	COG1381	Involved in DNA repair and RecF pathway recombination
Vc3S01_0517	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Vc3S01_0521	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Vc3S01_0522	COG3956	TIGRFAM MazG family protein
Vc3S01_0524	COG0148	phosphopyruvate hydratase activity
Vc3S01_0526	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Vc3S01_0532	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Vc3S01_0534	COG1546	Belongs to the CinA family
Vc3S01_0535	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Vc3S01_0538	COG0527	aspartate kinase activity
Vc3S01_0542	COG5016	pyruvate
Vc3S01_0542	COG0511	ligase activity, forming carbon-carbon bonds
Vc3S01_0543	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
Vc3S01_0545	COG1238	metal cluster binding
Vc3S01_0546	COG0612	Peptidase, M16
Vc3S01_0550	COG4536	flavin adenine dinucleotide binding
Vc3S01_0551	COG4137	Cytochrome C assembly protein
Vc3S01_0552	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Vc3S01_0558	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
Vc3S01_0559	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
Vc3S01_0560	COG0237	dephospho-CoA kinase activity
Vc3S01_0562	COG1459	type II secretion system
Vc3S01_0563	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vc3S01_0567	COG2186	Transcriptional regulator
Vc3S01_0568	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Vc3S01_0569	COG0508	dehydrogenase complex catalyzes the overall conversion of
Vc3S01_0570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vc3S01_0573	COG0288	reversible hydration of carbon dioxide
Vc3S01_0574	COG0659	secondary active sulfate transmembrane transporter activity
Vc3S01_0575	COG1131	(ABC) transporter
Vc3S01_0576	COG0842	Transport permease protein
Vc3S01_0577	COG1560	Kdo2-lipid A biosynthetic process
Vc3S01_0580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Vc3S01_0582	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Vc3S01_0583	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Vc3S01_0585	COG1643	Atp-dependent helicase
Vc3S01_0586	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Vc3S01_0587	COG1752	Esterase of the alpha-beta hydrolase superfamily
Vc3S01_0588	COG1049	propionate catabolic process, 2-methylcitrate cycle
Vc3S01_0591	COG0004	ammonium transporteR
Vc3S01_0592	COG1840	ABC-type Fe3 transport system, periplasmic component
Vc3S01_0594	COG3842	ATPase activity
Vc3S01_0595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Vc3S01_0598	COG2971	BadF BadG BcrA BcrD
Vc3S01_0600	COG4608	Belongs to the ABC transporter superfamily
Vc3S01_0601	COG0444	Belongs to the ABC transporter superfamily
Vc3S01_0602	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vc3S01_0604	COG0747	negative chemotaxis
Vc3S01_0605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vc3S01_0605	COG2205	protein histidine kinase activity
Vc3S01_0605	COG2198	Histidine kinase
Vc3S01_0605	COG0784	Response regulator, receiver
Vc3S01_0607	COG0628	permease
Vc3S01_0613	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vc3S01_0614	COG0739	heme binding
Vc3S01_0615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Vc3S01_0618	COG2027	D-alanyl-D-alanine carboxypeptidase
Vc3S01_0619	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vc3S01_0621	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Vc3S01_0622	COG1534	Rna-binding protein
Vc3S01_0624	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Vc3S01_0625	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Vc3S01_0627	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Vc3S01_0629	COG0195	Participates in both transcription termination and antitermination
Vc3S01_0633	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Vc3S01_0637	COG0534	Mate efflux family protein
Vc3S01_0642	COG3153	acetyltransferase
Vc3S01_0646	COG3706	GGDEF domain
Vc3S01_0649	COG0084	hydrolase, TatD family'
Vc3S01_0650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Vc3S01_0652	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Vc3S01_0654	COG0813	purine-nucleoside phosphorylase activity
Vc3S01_0656	COG0560	Phosphoserine phosphatase
Vc3S01_0658	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Vc3S01_0659	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Vc3S01_0660	COG0583	DNA-binding transcription factor activity
Vc3S01_0667	COG1022	Amp-dependent synthetase and ligase
Vc3S01_0668	COG2169	Transcriptional regulator
Vc3S01_0673	COG4964	Belongs to the GSP D family
Vc3S01_0685	COG0583	DNA-binding transcription factor activity
Vc3S01_0686	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
Vc3S01_0686	COG3408	Glycogen debranching enzyme
Vc3S01_0688	COG0531	amino acid
Vc3S01_0689	COG2731	YhcH YjgK YiaL family protein
Vc3S01_0690	COG3250	beta-galactosidase activity
Vc3S01_0691	COG1609	Transcriptional regulator
Vc3S01_0692	COG0768	penicillin binding
Vc3S01_0694	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Vc3S01_0695	COG1085	galactose-1-phosphate uridylyltransferase
Vc3S01_0697	COG2017	converts alpha-aldose to the beta-anomer
Vc3S01_0698	COG1609	Transcriptional regulator
Vc3S01_0699	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vc3S01_0699	COG1263	PTS System
Vc3S01_0702	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Vc3S01_0707	COG0741	lytic transglycosylase activity
Vc3S01_0708	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Vc3S01_0709	COG1349	DNA-binding transcription factor activity
Vc3S01_0711	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Vc3S01_0712	COG2271	Major facilitator Superfamily
Vc3S01_0713	COG0584	glycerophosphoryl diester phosphodiesterase
Vc3S01_0716	COG2171	N-acyltransferase activity
Vc3S01_0719	COG3141	response to X-ray
Vc3S01_0723	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
Vc3S01_0724	COG1074	ATP-dependent DNA helicase activity
Vc3S01_0725	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Vc3S01_0728	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Vc3S01_0728	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Vc3S01_0731	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Vc3S01_0732	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Vc3S01_0733	COG2166	iron-sulfur cluster assembly
Vc3S01_0734	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Vc3S01_0735	COG0693	protein deglycase activity
Vc3S01_0736	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Vc3S01_0740	COG1595	DNA-templated transcription, initiation
Vc3S01_0746	COG0271	Belongs to the BolA IbaG family
Vc3S01_0753	COG1477	protein flavinylation
Vc3S01_0755	COG0745	RESPONSE REGULATOR receiver
Vc3S01_0755	COG3706	GGDEF domain
Vc3S01_0756	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Vc3S01_0757	COG0514	ATP-dependent DNA helicase (RecQ)
Vc3S01_0758	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Vc3S01_0761	COG0733	neurotransmitter:sodium symporter activity
Vc3S01_0766	COG1720	tRNA m6t6A37 methyltransferase activity
Vc3S01_0769	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Vc3S01_0775	COG3098	single-species biofilm formation
Vc3S01_0776	COG0564	pseudouridine synthase activity
Vc3S01_0779	COG0024	Methionine aminopeptidase
Vc3S01_0784	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Vc3S01_0785	COG0575	Belongs to the CDS family
Vc3S01_0787	COG0750	zinc metalloprotease
Vc3S01_0789	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
Vc3S01_0790	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vc3S01_0795	COG0587	DNA-directed DNA polymerase activity
Vc3S01_0799	COG0347	Belongs to the P(II) protein family
Vc3S01_0802	COG0741	lytic transglycosylase activity
Vc3S01_0802	COG1388	LysM domain
Vc3S01_0804	COG2226	methyltransferase
Vc3S01_0806	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Vc3S01_0811	COG1960	acyl-CoA dehydrogenase activity
Vc3S01_0812	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Vc3S01_0813	COG0121	glutamine amidotransferase
Vc3S01_0814	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Vc3S01_0815	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Vc3S01_0816	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Vc3S01_0817	COG2233	PERMEase
Vc3S01_0821	COG1393	Belongs to the ArsC family
Vc3S01_0822	COG4783	chaperone-mediated protein folding
Vc3S01_0825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Vc3S01_0826	COG2716	regulation of RNA biosynthetic process
Vc3S01_0827	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Vc3S01_0832	COG1393	Belongs to the ArsC family
Vc3S01_0837	COG2837	iron assimilation
Vc3S01_0838	COG2169	Transcriptional regulator
Vc3S01_0839	COG1486	melibiose metabolic process
Vc3S01_0840	COG2211	Major facilitator Superfamily
Vc3S01_0842	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vc3S01_0843	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vc3S01_0844	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vc3S01_0845	COG1334	flagellar protein FlaG
Vc3S01_0846	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Vc3S01_0848	COG1516	flagellar protein fliS
Vc3S01_0850	COG4191	Histidine kinase
Vc3S01_0851	COG2204	response regulator
Vc3S01_0852	COG1677	Flagellar hook-basal body complex protein FliE
Vc3S01_0854	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Vc3S01_0865	COG1987	bacterial-type flagellum assembly
Vc3S01_0866	COG1684	flagellar biosynthetic protein fliR
Vc3S01_0870	COG0455	bacterial-type flagellum organization
Vc3S01_0873	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
Vc3S01_0874	COG0643	Histidine kinase
Vc3S01_0874	COG2198	Histidine kinase
Vc3S01_0875	COG2201	protein-glutamate methylesterase activity
Vc3S01_0876	COG1192	Involved in chromosome partitioning
Vc3S01_0878	COG0835	chemotaxis
Vc3S01_0880	COG4133	protoheme IX ABC transporter activity
Vc3S01_0881	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Vc3S01_0882	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Vc3S01_0885	COG1138	Cytochrome C-type biogenesis protein
Vc3S01_0886	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Vc3S01_0888	COG3088	subunit of a heme lyase
Vc3S01_0888	COG4235	cytochrome complex assembly
Vc3S01_0889	COG2853	Lipoprotein
Vc3S01_0891	COG2067	long-chain fatty acid transport protein
Vc3S01_0894	COG0183	Belongs to the thiolase family
Vc3S01_0898	COG2062	phosphohistidine phosphatase, SixA
Vc3S01_0900	COG2890	protein-(glutamine-N5) methyltransferase activity
Vc3S01_0903	COG2860	membrane
Vc3S01_0904	COG3101	peptidyl-lysine hydroxylation
Vc3S01_0909	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Vc3S01_0911	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vc3S01_0912	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Vc3S01_0916	COG0285	dihydrofolate synthase activity
Vc3S01_0917	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
Vc3S01_0918	COG1286	toxin biosynthetic process
Vc3S01_0919	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Vc3S01_0920	COG0583	DNA-binding transcription factor activity
Vc3S01_0921	COG0745	RESPONSE REGULATOR receiver
Vc3S01_0923	COG2832	Protein of unknown function (DUF454)
Vc3S01_0925	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Vc3S01_0927	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Vc3S01_0928	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Vc3S01_0929	COG0814	amino acid
Vc3S01_0930	COG0251	oxidation-reduction process
Vc3S01_0932	COG2964	Protein conserved in bacteria
Vc3S01_0934	COG2983	Belongs to the UPF0260 family
Vc3S01_0935	COG2261	transglycosylase associated protein
Vc3S01_0936	COG2985	domain, Protein
Vc3S01_0937	COG0076	glutamate decarboxylase activity
Vc3S01_0938	COG0668	transmembrane transport
Vc3S01_0940	COG0346	lactoylglutathione lyase activity
Vc3S01_0942	COG1785	Belongs to the alkaline phosphatase family
Vc3S01_0946	COG2226	methyltransferase
Vc3S01_0950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Vc3S01_0951	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vc3S01_0953	COG3139	Protein of unknown function (DUF1315)
Vc3S01_0954	COG0252	asparaginase activity
Vc3S01_0955	COG0616	signal peptide processing
Vc3S01_0956	COG0446	pyridine nucleotide-disulphide oxidoreductase
Vc3S01_0956	COG1902	pentaerythritol trinitrate reductase activity
Vc3S01_0957	COG0778	Nitroreductase
Vc3S01_0958	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Vc3S01_0962	COG0123	including yeast histone deacetylase and acetoin utilization protein
Vc3S01_0964	COG4269	membrane
Vc3S01_0966	COG3083	sulfuric ester hydrolase activity
Vc3S01_0971	COG1757	Na H antiporter
Vc3S01_0972	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Vc3S01_0974	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Vc3S01_0975	COG2095	MarC family integral membrane protein
Vc3S01_0976	COG1454	alcohol dehydrogenase
Vc3S01_0976	COG1012	belongs to the aldehyde dehydrogenase family
Vc3S01_0977	COG1028	Short-chain dehydrogenase reductase Sdr
Vc3S01_0980	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Vc3S01_0981	COG4974	Belongs to the 'phage' integrase family
Vc3S01_0985	COG1403	HNH endonuclease
Vc3S01_1016	COG3504	Conjugal transfer protein
Vc3S01_1017	COG3736	Type IV secretory pathway, component VirB8
Vc3S01_1022	COG3451	type IV secretory pathway VirB4
Vc3S01_1029	COG2056	Na+-H+ antiporter family
Vc3S01_1031	COG2885	chlorophyll binding
Vc3S01_1033	COG0346	lactoylglutathione lyase activity
Vc3S01_1034	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Vc3S01_1035	COG4660	Part of a membrane complex involved in electron transport
Vc3S01_1036	COG4659	FMN binding
Vc3S01_1037	COG4658	electron transport chain
Vc3S01_1038	COG4656	Part of a membrane complex involved in electron transport
Vc3S01_1040	COG4657	Part of a membrane complex involved in electron transport
Vc3S01_1041	COG1882	Formate acetyltransferase
Vc3S01_1042	COG0745	RESPONSE REGULATOR receiver
Vc3S01_1047	COG0556	nucleotide-excision repair
Vc3S01_1050	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Vc3S01_1051	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Vc3S01_1052	COG0521	Mo-molybdopterin cofactor biosynthetic process
Vc3S01_1054	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Vc3S01_1055	COG0314	molybdopterin synthase activity
Vc3S01_1057	COG0601	transmembrane transport
Vc3S01_1058	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vc3S01_1059	COG0444	Belongs to the ABC transporter superfamily
Vc3S01_1061	COG0435	Glutathione S-transferase
Vc3S01_1062	COG3174	membrane
Vc3S01_1063	COG0280	phosphate acetyltransferase
Vc3S01_1063	COG0857	belongs to the CobB CobQ family
Vc3S01_1067	COG4120	Belongs to the binding-protein-dependent transport system permease family
Vc3S01_1068	COG1122	ATPase activity
Vc3S01_1069	COG0366	Alpha amylase catalytic
Vc3S01_1070	COG3706	GGDEF domain
Vc3S01_1070	COG0745	RESPONSE REGULATOR receiver
Vc3S01_1071	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Vc3S01_1073	COG0653	protein targeting
Vc3S01_1074	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Vc3S01_1076	COG2186	Transcriptional regulator
Vc3S01_1082	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
Vc3S01_1083	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Vc3S01_1084	COG0659	secondary active sulfate transmembrane transporter activity
Vc3S01_1085	COG1530	ribonuclease E activity
Vc3S01_1087	COG0564	pseudouridine synthase activity
Vc3S01_1088	COG0424	maF-like protein
Vc3S01_1089	COG1399	metal-binding, possibly nucleic acid-binding protein
Vc3S01_1092	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Vc3S01_1098	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Vc3S01_1101	COG0084	hydrolase, TatD family'
Vc3S01_1102	COG1263	PTS System
Vc3S01_1102	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vc3S01_1104	COG0733	neurotransmitter:sodium symporter activity
Vc3S01_1107	COG4667	esterase of the alpha-beta hydrolase superfamily
Vc3S01_1112	COG2272	Belongs to the type-B carboxylesterase lipase family
Vc3S01_1113	COG3710	Transcriptional regulator
Vc3S01_1116	COG1940	carbohydrate kinase activity
Vc3S01_1117	COG0784	Response regulator, receiver
Vc3S01_1117	COG0835	chemotaxis
Vc3S01_1121	COG1028	Short-chain dehydrogenase reductase Sdr
Vc3S01_1123	COG0616	signal peptide processing
Vc3S01_1126	COG0539	negative regulation of cytoplasmic translation
Vc3S01_1128	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
Vc3S01_1129	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
Vc3S01_1131	COG4166	transmembrane transport
Vc3S01_1135	COG3009	Protein conserved in bacteria
Vc3S01_1136	COG3008	intermembrane lipid transfer
Vc3S01_1136	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Vc3S01_1137	COG2995	paraquat-inducible protein a
Vc3S01_1140	COG4232	protein-disulfide reductase activity
Vc3S01_1141	COG3118	belongs to the thioredoxin family
Vc3S01_1143	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Vc3S01_1149	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vc3S01_1151	COG0577	efflux transmembrane transporter activity
Vc3S01_1152	COG1136	(ABC) transporter
Vc3S01_1152	COG0577	efflux transmembrane transporter activity
Vc3S01_1153	COG0577	efflux transmembrane transporter activity
Vc3S01_1153	COG1136	(ABC) transporter
Vc3S01_1156	COG2176	DNA-directed DNA polymerase activity
Vc3S01_1159	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Vc3S01_1168	COG0515	serine threonine protein kinase
Vc3S01_1169	COG5002	protein histidine kinase activity
Vc3S01_1169	COG3850	Histidine kinase
Vc3S01_1170	COG0745	RESPONSE REGULATOR receiver
Vc3S01_1171	COG0463	Glycosyl transferase, family 2
Vc3S01_1172	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Vc3S01_1174	COG0840	transmembrane signaling receptor activity
Vc3S01_1175	COG2175	clavaminate synthase activity
Vc3S01_1177	COG2964	Protein conserved in bacteria
Vc3S01_1180	COG0446	pyridine nucleotide-disulphide oxidoreductase
Vc3S01_1184	COG1032	radical SAM domain protein
Vc3S01_1185	COG1716	ATPase activity
Vc3S01_1185	COG5001	Diguanylate cyclase
Vc3S01_1188	COG0583	DNA-binding transcription factor activity
Vc3S01_1191	COG2350	Protein conserved in bacteria
Vc3S01_1192	COG1607	acyl-coa hydrolase
Vc3S01_1197	COG1301	dicarboxylic acid transport
Vc3S01_1198	COG0159	tryptophan synthase activity
Vc3S01_1200	COG0135	phosphoribosylanthranilate isomerase activity
Vc3S01_1200	COG0134	indole-3-glycerol-phosphate synthase activity
Vc3S01_1202	COG0512	Glutamine amidotransferase of anthranilate synthase
Vc3S01_1203	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Vc3S01_1205	COG0613	PHP domain protein
Vc3S01_1206	COG0009	L-threonylcarbamoyladenylate synthase
Vc3S01_1208	COG1187	pseudouridine synthase activity
Vc3S01_1212	COG0417	DNA replication proofreading
Vc3S01_1213	COG2197	response regulator
Vc3S01_1215	COG0322	excinuclease ABC activity
Vc3S01_1219	COG0019	diaminopimelate decarboxylase activity
Vc3S01_1222	COG1058	Belongs to the CinA family
Vc3S01_1222	COG1546	Belongs to the CinA family
Vc3S01_1224	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Vc3S01_1225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Vc3S01_1230	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
Vc3S01_1232	COG0437	4 iron, 4 sulfur cluster binding
Vc3S01_1233	COG3301	Polysulphide reductase, NrfD
Vc3S01_1234	COG1138	Cytochrome C-type biogenesis protein
Vc3S01_1236	COG4235	cytochrome complex assembly
Vc3S01_1236	COG3088	subunit of a heme lyase
Vc3S01_1243	COG2989	Protein conserved in bacteria
Vc3S01_1244	COG3108	Peptidase M15
Vc3S01_1245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Vc3S01_1248	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Vc3S01_1253	COG1846	Transcriptional regulator
Vc3S01_1254	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vc3S01_1255	COG0840	transmembrane signaling receptor activity
Vc3S01_1260	COG1448	Aminotransferase
Vc3S01_1261	COG2770	Histidine kinase
Vc3S01_1261	COG3437	response regulator, receiver
Vc3S01_1264	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vc3S01_1267	COG0017	Asparaginyl-tRNA synthetase
Vc3S01_1269	COG0720	synthase
Vc3S01_1270	COG2197	response regulator
Vc3S01_1274	COG1760	l-serine dehydratase
Vc3S01_1275	COG0814	amino acid
Vc3S01_1279	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Vc3S01_1282	COG3106	COG3106 Predicted ATPase
Vc3S01_1285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vc3S01_1304	COG0519	Catalyzes the synthesis of GMP from XMP
Vc3S01_1376	COG0494	nUDIX hydrolase
Vc3S01_1377	COG1714	RDD family
Vc3S01_1380	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Vc3S01_1397	COG4221	oxidoreductase activity
Vc3S01_1400	COG3340	Belongs to the peptidase S51 family
Vc3S01_1404	COG0456	acetyltransferase
Vc3S01_1405	COG0471	metal ion transport
Vc3S01_1406	COG4191	Histidine kinase
Vc3S01_1406	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vc3S01_1411	COG1328	CTP reductase activity
Vc3S01_1412	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Vc3S01_1414	COG0861	Integral membrane protein TerC family
Vc3S01_1416	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Vc3S01_1417	COG4221	oxidoreductase activity
Vc3S01_1418	COG1454	alcohol dehydrogenase
Vc3S01_1419	COG0814	amino acid
Vc3S01_1424	COG1132	(ABC) transporter
Vc3S01_1425	COG1132	(ABC) transporter
Vc3S01_1427	COG0583	DNA-binding transcription factor activity
Vc3S01_1432	COG0443	Heat shock 70 kDa protein
Vc3S01_1433	COG0443	Heat shock 70 kDa protein
Vc3S01_1435	COG3706	GGDEF domain
Vc3S01_1441	COG3227	Zinc metalloprotease (Elastase)
Vc3S01_1445	COG3842	ATPase activity
Vc3S01_1446	COG3459	Glycosyltransferase 36 associated
Vc3S01_1448	COG1653	transport
Vc3S01_1449	COG1175	transmembrane transport
Vc3S01_1450	COG0395	ABC-type sugar transport system, permease component
Vc3S01_1453	COG0243	molybdopterin cofactor binding
Vc3S01_1454	COG0437	4 iron, 4 sulfur cluster binding
Vc3S01_1455	COG3302	dmso reductase anchor subunit
Vc3S01_1457	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Vc3S01_1458	COG1643	Atp-dependent helicase
Vc3S01_1463	COG3063	Type IV pilus biogenesis stability protein PilW
Vc3S01_1469	COG0531	amino acid
Vc3S01_1471	COG1280	lysine exporter protein (LysE YggA)
Vc3S01_1472	COG1560	Kdo2-lipid A biosynthetic process
Vc3S01_1476	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Vc3S01_1477	COG1280	lysine exporter protein (LysE YggA)
Vc3S01_1486	COG1115	amino acid carrier protein
Vc3S01_1491	COG1368	sulfuric ester hydrolase activity
Vc3S01_1494	COG0215	cysteine-tRNA ligase activity
Vc3S01_1495	COG0534	Mate efflux family protein
Vc3S01_1496	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
Vc3S01_1498	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vc3S01_1499	COG0456	acetyltransferase
Vc3S01_1500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Vc3S01_1501	COG0662	Cupin 2, conserved barrel domain protein
Vc3S01_1502	COG0527	aspartate kinase activity
Vc3S01_1503	COG1858	cytochrome C peroxidase
Vc3S01_1504	COG1404	Belongs to the peptidase S8 family
Vc3S01_1505	COG3227	Zinc metalloprotease (Elastase)
Vc3S01_1508	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Vc3S01_1509	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Vc3S01_1510	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Vc3S01_1516	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Vc3S01_1517	COG0667	Aldo Keto reductase
Vc3S01_1520	COG0583	DNA-binding transcription factor activity
Vc3S01_1521	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vc3S01_1522	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Vc3S01_1523	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Vc3S01_1524	COG0679	Auxin Efflux Carrier
Vc3S01_1534	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Vc3S01_1542	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vc3S01_1546	COG3290	protein histidine kinase activity
Vc3S01_1547	COG4565	transcriptional regulatory protein
Vc3S01_1548	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Vc3S01_1549	COG0363	glucosamine-6-phosphate deaminase activity
Vc3S01_1550	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Vc3S01_1555	COG3284	Transcriptional regulator
Vc3S01_1556	COG1012	belongs to the aldehyde dehydrogenase family
Vc3S01_1558	COG0730	response to heat
Vc3S01_1564	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Vc3S01_1565	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Vc3S01_1584	COG3501	Rhs element vgr protein
Vc3S01_1587	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Vc3S01_1588	COG0372	Belongs to the citrate synthase family
Vc3S01_1590	COG2828	Protein conserved in bacteria
Vc3S01_1593	COG3119	arylsulfatase activity
Vc3S01_1598	COG0561	phosphatase activity
Vc3S01_1599	COG0602	queuosine metabolic process
Vc3S01_1601	COG3706	GGDEF domain
Vc3S01_1610	COG0840	transmembrane signaling receptor activity
Vc3S01_1611	COG1254	Belongs to the acylphosphatase family
Vc3S01_1612	COG2920	part of a sulfur-relay system
Vc3S01_1614	COG0670	Belongs to the BI1 family
Vc3S01_1615	COG1126	abc transporter atp-binding protein
Vc3S01_1616	COG0765	amino acid transport
Vc3S01_1617	COG4597	amino acid ABC transporter
Vc3S01_1618	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vc3S01_1621	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Vc3S01_1626	COG3008	intermembrane lipid transfer
Vc3S01_1627	COG2995	paraquat-inducible protein a
Vc3S01_1628	COG1132	(ABC) transporter
Vc3S01_1629	COG1956	GAF domain-containing protein
Vc3S01_1630	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
Vc3S01_1633	COG0308	aminopeptidase N
Vc3S01_1634	COG2902	Dehydrogenase
Vc3S01_1643	COG1067	ATP-dependent peptidase activity
Vc3S01_1649	COG2801	Transposase and inactivated derivatives
Vc3S01_1650	COG0784	Response regulator, receiver
Vc3S01_1650	COG2205	protein histidine kinase activity
Vc3S01_1653	COG3278	Belongs to the heme-copper respiratory oxidase family
Vc3S01_1656	COG2010	Cytochrome c
Vc3S01_1658	COG2217	Heavy metal translocating P-type atpase
Vc3S01_1661	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Vc3S01_1663	COG0589	response to stress
Vc3S01_1668	COG3842	ATPase activity
Vc3S01_1669	COG1176	ABC-type spermidine putrescine transport system, permease component I
Vc3S01_1670	COG1177	transmembrane transport
Vc3S01_1671	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Vc3S01_1672	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Vc3S01_1673	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Vc3S01_1677	COG0437	4 iron, 4 sulfur cluster binding
Vc3S01_1678	COG3383	formate dehydrogenase (NAD+) activity
Vc3S01_1678	COG0243	molybdopterin cofactor binding
Vc3S01_1680	COG3381	protein complex oligomerization
Vc3S01_1685	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Vc3S01_1688	COG0488	(ABC) transporter
Vc3S01_1691	COG4191	Histidine kinase
Vc3S01_1692	COG2204	response regulator
Vc3S01_1694	COG4662	Binding-protein-dependent transport system inner membrane component
Vc3S01_1695	COG3842	ATPase activity
Vc3S01_1697	COG0303	'Molybdopterin
Vc3S01_1699	COG1940	carbohydrate kinase activity
Vc3S01_1708	COG0840	transmembrane signaling receptor activity
Vc3S01_1708	COG3290	protein histidine kinase activity
Vc3S01_1709	COG0791	NLP P60 protein
Vc3S01_1711	COG3706	GGDEF domain
Vc3S01_1712	COG2201	protein-glutamate methylesterase activity
Vc3S01_1715	COG0307	riboflavin synthase, alpha
Vc3S01_1716	COG0534	Mate efflux family protein
Vc3S01_1718	COG1793	dna ligase
Vc3S01_1720	COG2885	chlorophyll binding
Vc3S01_1724	COG2204	response regulator
Vc3S01_1725	COG0438	transferase activity, transferring glycosyl groups
Vc3S01_1726	COG0438	transferase activity, transferring glycosyl groups
Vc3S01_1732	COG0438	transferase activity, transferring glycosyl groups
Vc3S01_1733	COG1215	transferase activity, transferring glycosyl groups
Vc3S01_1734	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Vc3S01_1736	COG3064	Membrane
Vc3S01_1741	COG5001	Diguanylate cyclase
Vc3S01_1741	COG3300	MHYT domain
Vc3S01_1742	COG3850	Histidine kinase
Vc3S01_1742	COG4999	Histidine kinase
Vc3S01_1742	COG3437	response regulator, receiver
Vc3S01_1742	COG2205	protein histidine kinase activity
Vc3S01_1746	COG0110	maltose O-acetyltransferase activity
Vc3S01_1751	COG1846	Transcriptional regulator
Vc3S01_1753	COG1482	cell wall glycoprotein biosynthetic process
Vc3S01_1756	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vc3S01_1760	COG0383	alpha-mannosidase activity
Vc3S01_1762	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
Vc3S01_1767	COG3247	response to pH
Vc3S01_1768	COG0668	transmembrane transport
Vc3S01_1770	COG1404	Belongs to the peptidase S8 family
Vc3S01_1772	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
Vc3S01_1784	COG2199	diguanylate cyclase activity
Vc3S01_1784	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Vc3S01_1791	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vc3S01_1793	COG0786	glutamate:sodium symporter activity
Vc3S01_1796	COG0625	glutathione transferase activity
Vc3S01_1798	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
Vc3S01_1801	COG2195	Cleaves the N-terminal amino acid of tripeptides
Vc3S01_1806	COG0813	purine-nucleoside phosphorylase activity
Vc3S01_1809	COG0745	RESPONSE REGULATOR receiver
Vc3S01_1809	COG3706	GGDEF domain
Vc3S01_1811	COG1451	nucleotide metabolic process
Vc3S01_1812	COG4932	domain protein
Vc3S01_1812	COG5492	domain, Protein
Vc3S01_1815	COG2201	protein-glutamate methylesterase activity
Vc3S01_1827	COG4968	Prepilin-type N-terminal cleavage methylation domain
Vc3S01_1832	COG0583	DNA-binding transcription factor activity
Vc3S01_1838	COG4139	cobalamin transport
Vc3S01_1841	COG2062	phosphohistidine phosphatase, SixA
Vc3S01_1843	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Vc3S01_1845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Vc3S01_1846	COG0702	epimerase
Vc3S01_1849	COG2925	Exonuclease
Vc3S01_1851	COG1346	cytolysis
Vc3S01_1861	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vc3S01_1862	COG4605	iron ion homeostasis
Vc3S01_1863	COG4607	ABC-type enterochelin transport system periplasmic component
Vc3S01_1864	COG4774	siderophore transport
Vc3S01_1865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vc3S01_1866	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
Vc3S01_1868	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vc3S01_1873	COG3433	isochorismatase activity
Vc3S01_1873	COG1535	isochorismatase
Vc3S01_1874	COG0072	phenylalanine-tRNA ligase activity
Vc3S01_1874	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Vc3S01_1876	COG3706	GGDEF domain
Vc3S01_1885	COG0251	oxidation-reduction process
Vc3S01_1893	COG2188	Transcriptional regulator
Vc3S01_1895	COG0010	Belongs to the arginase family
Vc3S01_1897	COG2986	histidine ammonia-lyase
Vc3S01_1906	COG0247	lactate metabolic process
Vc3S01_1906	COG0277	FAD linked oxidase domain protein
Vc3S01_1918	COG1643	Atp-dependent helicase
Vc3S01_1920	COG2949	membrane
Vc3S01_1921	COG0471	metal ion transport
Vc3S01_1922	COG3706	GGDEF domain
Vc3S01_1926	COG0492	ferredoxin-NADP+ reductase activity
Vc3S01_1927	COG4988	ABC transporter
Vc3S01_1928	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Vc3S01_1930	COG2610	gluconate transmembrane transporter activity
Vc3S01_1931	COG0583	DNA-binding transcription factor activity
Vc3S01_1932	COG2200	EAL domain
Vc3S01_1938	COG5001	Diguanylate cyclase
Vc3S01_1941	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Vc3S01_1943	COG4191	Histidine kinase
Vc3S01_1943	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vc3S01_1946	COG3070	regulator of competence-specific genes
Vc3S01_1948	COG2431	L-lysine efflux transmembrane transporter activity
Vc3S01_1950	COG0076	glutamate decarboxylase activity
Vc3S01_1951	COG1737	Transcriptional regulator
Vc3S01_1953	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Vc3S01_1955	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Vc3S01_1961	COG4181	ATPase activity
Vc3S01_1962	COG0534	Mate efflux family protein
Vc3S01_1963	COG0702	epimerase
Vc3S01_1965	COG4667	esterase of the alpha-beta hydrolase superfamily
Vc3S01_1967	COG2814	Major facilitator Superfamily
Vc3S01_1968	COG1187	pseudouridine synthase activity
Vc3S01_1969	COG1061	Type III restriction enzyme res subunit
Vc3S01_1972	COG2199	diguanylate cyclase activity
Vc3S01_1974	COG0745	RESPONSE REGULATOR receiver
Vc3S01_1975	COG2205	protein histidine kinase activity
Vc3S01_1985	COG0659	secondary active sulfate transmembrane transporter activity
Vc3S01_1990	COG0493	'glutamate synthase
Vc3S01_1992	COG0398	Pfam SNARE associated Golgi protein
Vc3S01_1993	COG4134	Bacterial extracellular solute-binding protein
Vc3S01_1994	COG4135	transport system, permease component
Vc3S01_1995	COG4136	ATPase activity
Vc3S01_1996	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Vc3S01_1998	COG2814	Major facilitator Superfamily
Vc3S01_2000	COG3604	Transcriptional regulator
Vc3S01_2001	COG1151	hydroxylamine reductase activity
Vc3S01_2002	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Vc3S01_2004	COG0564	pseudouridine synthase activity
Vc3S01_2006	COG0733	neurotransmitter:sodium symporter activity
Vc3S01_2008	COG0626	cystathionine gamma-synthase activity
Vc3S01_2009	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
Vc3S01_2013	COG2818	Glycosylase
Vc3S01_2017	COG1983	PspC domain protein
Vc3S01_2019	COG1842	Phage shock protein A
Vc3S01_2020	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Vc3S01_2022	COG4168	peptide transport system, permease
Vc3S01_2023	COG4171	peptide transport system, permease
Vc3S01_2025	COG4172	Belongs to the ABC transporter superfamily
Vc3S01_2027	COG1227	inorganic diphosphatase activity
Vc3S01_2030	COG0243	molybdopterin cofactor binding
Vc3S01_2031	COG3005	denitrification pathway
Vc3S01_2032	COG4459	periplasmic nitrate reductase
Vc3S01_2033	COG0390	transport system, permease component
Vc3S01_2035	COG2116	formate transmembrane transporter activity
Vc3S01_2040	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Vc3S01_2041	COG1435	thymidine kinase activity
Vc3S01_2042	COG0215	cysteine-tRNA ligase activity
Vc3S01_2043	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Vc3S01_2044	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vc3S01_2045	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Vc3S01_2046	COG3012	SEC-C Motif Domain Protein
Vc3S01_2047	COG0140	phosphoribosyl-ATP diphosphatase activity
Vc3S01_2047	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Vc3S01_2048	COG0107	imidazoleglycerol-phosphate synthase activity
Vc3S01_2049	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Vc3S01_2050	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Vc3S01_2051	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Vc3S01_2051	COG0131	Imidazoleglycerol-phosphate dehydratase
Vc3S01_2053	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Vc3S01_2056	COG1757	Na H antiporter
Vc3S01_2058	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vc3S01_2062	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Vc3S01_2066	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Vc3S01_2069	COG0300	oxidoreductase activity
Vc3S01_2074	COG2226	methyltransferase
Vc3S01_2078	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Vc3S01_2082	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Vc3S01_2084	COG1674	ftsk spoiiie
Vc3S01_2086	COG0686	Belongs to the AlaDH PNT family
Vc3S01_2088	COG0583	DNA-binding transcription factor activity
Vc3S01_2093	COG0402	S-adenosylhomocysteine deaminase activity
Vc3S01_2094	COG4934	collagen metabolic process
Vc3S01_2099	COG3568	Endonuclease Exonuclease Phosphatase
Vc3S01_2103	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Vc3S01_2106	COG1288	antiporter activity
Vc3S01_2108	COG2186	Transcriptional regulator
Vc3S01_2110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vc3S01_2111	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vc3S01_2116	COG0747	negative chemotaxis
Vc3S01_2117	COG4608	Belongs to the ABC transporter superfamily
Vc3S01_2118	COG0444	Belongs to the ABC transporter superfamily
Vc3S01_2119	COG0534	Mate efflux family protein
Vc3S01_2121	COG2824	Alkylphosphonate utilization operon protein PhnA
Vc3S01_2125	COG3119	arylsulfatase activity
Vc3S01_2134	COG0457	Tetratricopeptide repeat
Vc3S01_2147	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Vc3S01_2148	COG4790	Type iii secretion
Vc3S01_2149	COG4794	Type iii secretion
Vc3S01_2150	COG4791	protein targeting
Vc3S01_2151	COG4792	protein secretion
Vc3S01_2154	COG3177	Filamentation induced by cAMP protein fic
Vc3S01_2160	COG4669	(LipO)protein
Vc3S01_2178	COG0784	Response regulator, receiver
Vc3S01_2178	COG2205	protein histidine kinase activity
Vc3S01_2180	COG0754	glutathionylspermidine amidase activity
Vc3S01_2182	COG3766	membrane
Vc3S01_2185	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
Vc3S01_2186	COG2885	chlorophyll binding
Vc3S01_2187	COG0823	Involved in the tonB-independent uptake of proteins
Vc3S01_2190	COG0811	peptide transport
Vc3S01_2191	COG0824	Thioesterase
Vc3S01_2193	COG1294	oxidase, subunit
Vc3S01_2194	COG1271	oxidase subunit
Vc3S01_2196	COG0632	four-way junction helicase activity
Vc3S01_2197	COG0840	transmembrane signaling receptor activity
Vc3S01_2200	COG1801	Protein of unknown function DUF72
Vc3S01_2203	COG0189	ligase activity
Vc3S01_2203	COG4067	protein conserved in archaea
Vc3S01_2208	COG0318	PFAM AMP-dependent synthetase and ligase
Vc3S01_2212	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Vc3S01_2213	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
Vc3S01_2215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Vc3S01_2216	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Vc3S01_2217	COG0745	RESPONSE REGULATOR receiver
Vc3S01_2220	COG3070	regulator of competence-specific genes
Vc3S01_2224	COG0297	glycogen (starch) synthase activity
Vc3S01_2225	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Vc3S01_2226	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Vc3S01_2232	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Vc3S01_2233	COG0542	response to heat
Vc3S01_2235	COG1278	Cold shock
Vc3S01_2237	COG1187	pseudouridine synthase activity
Vc3S01_2238	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
Vc3S01_2240	COG1199	ATP-dependent helicase activity
Vc3S01_2241	COG0730	response to heat
Vc3S01_2242	COG3923	Primosomal replication protein n
Vc3S01_2244	COG0708	Exodeoxyribonuclease III
Vc3S01_2246	COG4215	(ABC) transporter
Vc3S01_2251	COG1882	Formate acetyltransferase
Vc3S01_2253	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Vc3S01_2256	COG2766	serine protein kinase
Vc3S01_2257	COG2718	Belongs to the UPF0229 family
Vc3S01_2258	COG2719	SpoVR family
Vc3S01_2262	COG1132	(ABC) transporter
Vc3S01_2263	COG0658	competence protein
Vc3S01_2263	COG2333	competence protein COMEC
Vc3S01_2265	COG4591	ABC-type transport system involved in lipoprotein release permease component
Vc3S01_2266	COG1136	(ABC) transporter
Vc3S01_2267	COG4591	ABC-type transport system involved in lipoprotein release permease component
Vc3S01_2269	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Vc3S01_2272	COG1252	NADH dehydrogenase
Vc3S01_2278	COG0537	adenosine 5'-monophosphoramidase activity
Vc3S01_2282	COG2217	Heavy metal translocating P-type atpase
Vc3S01_2284	COG0516	GMP reductase activity
Vc3S01_2284	COG0517	IMP dehydrogenase activity
Vc3S01_2285	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Vc3S01_2286	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Vc3S01_2287	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Vc3S01_2288	COG3706	GGDEF domain
Vc3S01_2291	COG3126	Type III secretion system lipoprotein chaperone (YscW)
Vc3S01_2292	COG1946	Acyl-CoA thioesterase
Vc3S01_2293	COG1522	sequence-specific DNA binding
Vc3S01_2299	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vc3S01_2304	COG2855	membrane
Vc3S01_2306	COG0583	DNA-binding transcription factor activity
Vc3S01_2307	COG2190	(PTS) system
Vc3S01_2307	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vc3S01_2307	COG1263	PTS System
Vc3S01_2309	COG1441	menaquinone biosynthetic process
Vc3S01_2310	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Vc3S01_2311	COG0596	Alpha beta hydrolase
Vc3S01_2313	COG1169	isochorismate synthase
Vc3S01_2314	COG0436	Aminotransferase
Vc3S01_2315	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
Vc3S01_2319	COG1555	photosystem II stabilization
Vc3S01_2320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vc3S01_2321	COG0776	regulation of translation
Vc3S01_2322	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Vc3S01_2329	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Vc3S01_2330	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Vc3S01_2331	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vc3S01_2335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vc3S01_2336	COG0569	domain protein
Vc3S01_2337	COG0513	Belongs to the DEAD box helicase family
Vc3S01_2338	COG1253	flavin adenine dinucleotide binding
Vc3S01_2339	COG4771	TonB-dependent receptor
Vc3S01_2340	COG2977	Belongs to the P-Pant transferase superfamily
Vc3S01_2342	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vc3S01_2342	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vc3S01_2343	COG1535	isochorismatase
Vc3S01_2343	COG3433	isochorismatase activity
Vc3S01_2344	COG1021	2,3-dihydroxybenzoate-AMP ligase
Vc3S01_2345	COG1169	isochorismate synthase
Vc3S01_2347	COG1028	Short-chain dehydrogenase reductase Sdr
Vc3S01_2353	COG1104	cysteine desulfurase activity
Vc3S01_2357	COG0556	nucleotide-excision repair
Vc3S01_2364	COG2852	Protein conserved in bacteria
Vc3S01_2365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Vc3S01_2367	COG2951	lytic endotransglycosylase activity
Vc3S01_2370	COG2894	cell division
Vc3S01_2371	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Vc3S01_2372	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Vc3S01_2373	COG0318	PFAM AMP-dependent synthetase and ligase
Vc3S01_2374	COG2267	carboxylic ester hydrolase activity
Vc3S01_2375	COG3065	identical protein binding
Vc3S01_2377	COG1214	PFAM Peptidase M22, glycoprotease
Vc3S01_2378	COG1199	ATP-dependent helicase activity
Vc3S01_2380	COG0788	formyltetrahydrofolate deformylase activity
Vc3S01_2383	COG3102	Protein conserved in bacteria
Vc3S01_2389	COG1918	ferrous iron import across plasma membrane
Vc3S01_2390	COG4977	sequence-specific DNA binding
Vc3S01_2391	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
Vc3S01_2392	COG1121	(ABC) transporter
Vc3S01_2393	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Vc3S01_2396	COG0508	dehydrogenase complex catalyzes the overall conversion of
Vc3S01_2397	COG0567	Dehydrogenase, E1 component
Vc3S01_2399	COG1053	succinate dehydrogenase
Vc3S01_2400	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Vc3S01_2401	COG2009	succinate dehydrogenase
Vc3S01_2403	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Vc3S01_2405	COG0033	Phosphoglucomutase
Vc3S01_2407	COG0596	Alpha beta hydrolase
Vc3S01_2411	COG0735	belongs to the Fur family
Vc3S01_2412	COG2165	general secretion pathway protein
Vc3S01_2414	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vc3S01_2414	COG2190	(PTS) system
Vc3S01_2414	COG1263	PTS System
Vc3S01_2415	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Vc3S01_2416	COG1846	Transcriptional regulator
Vc3S01_2416	COG1940	carbohydrate kinase activity
Vc3S01_2417	COG4651	solute:proton antiporter activity
Vc3S01_2417	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Vc3S01_2418	COG0367	asparagine synthase
Vc3S01_2420	COG3104	oligopeptide transport
Vc3S01_2421	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Vc3S01_2424	COG3710	Transcriptional regulator
Vc3S01_2428	COG0622	Phosphoesterase
Vc3S01_2434	COG1090	epimerase
Vc3S01_2435	COG0300	oxidoreductase activity
Vc3S01_2437	COG3118	belongs to the thioredoxin family
Vc3S01_2438	COG0457	Tetratricopeptide repeat
Vc3S01_2438	COG3118	belongs to the thioredoxin family
Vc3S01_2439	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
Vc3S01_2440	COG1215	transferase activity, transferring glycosyl groups
Vc3S01_2441	COG1215	transferase activity, transferring glycosyl groups
Vc3S01_2442	COG1192	Involved in chromosome partitioning
Vc3S01_2446	COG2194	sulfuric ester hydrolase activity
Vc3S01_2447	COG0330	HflC and HflK could
Vc3S01_2454	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
Vc3S01_2455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Vc3S01_2456	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vc3S01_2457	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Vc3S01_2458	COG2190	(PTS) system
Vc3S01_2459	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vc3S01_2460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vc3S01_2461	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vc3S01_2465	COG3951	Flagellar rod assembly protein muramidase FlgJ
Vc3S01_2465	COG1705	Flagellar rod assembly protein muramidase FlgJ
Vc3S01_2466	COG1706	bacterial-type flagellum-dependent cell motility
Vc3S01_2467	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Vc3S01_2468	COG4786	Flagellar basal body rod
Vc3S01_2469	COG4787	bacterial-type flagellum-dependent cell motility
Vc3S01_2471	COG1749	Flagellar hook protein flgE
Vc3S01_2472	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Vc3S01_2473	COG1558	bacterial-type flagellum-dependent cell motility
Vc3S01_2474	COG1815	bacterial-type flagellum-dependent cell motility
Vc3S01_2475	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Vc3S01_2476	COG0835	chemotaxis
Vc3S01_2476	COG0784	Response regulator, receiver
Vc3S01_2487	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
Vc3S01_2489	COG2217	Heavy metal translocating P-type atpase
Vc3S01_2489	COG2608	mercury ion transmembrane transporter activity
Vc3S01_2496	COG2840	Smr protein MutS2
Vc3S01_2497	COG1187	pseudouridine synthase activity
Vc3S01_2498	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Vc3S01_2499	COG0737	Belongs to the 5'-nucleotidase family
Vc3S01_2501	COG2912	Transglutaminase-like superfamily
Vc3S01_2502	COG3094	Invasion gene expression up-regulator, SirB
Vc3S01_2503	COG2890	protein-(glutamine-N5) methyltransferase activity
Vc3S01_2508	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Vc3S01_2512	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vc3S01_2514	COG1702	phosphate starvation-inducible protein PhoH
Vc3S01_2516	COG4535	Mg2 and Co2 transporter CorC
Vc3S01_2517	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Vc3S01_2518	COG2888	peptidyl-tyrosine sulfation
Vc3S01_2520	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
Vc3S01_2521	COG1466	dna polymerase III delta subunit
Vc3S01_2522	COG0799	negative regulation of ribosome biogenesis
Vc3S01_2524	COG0768	penicillin binding
Vc3S01_2525	COG0772	Belongs to the SEDS family
Vc3S01_2526	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Vc3S01_2527	COG1686	Belongs to the peptidase S11 family
Vc3S01_2531	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Vc3S01_2532	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Vc3S01_2535	COG0366	Alpha amylase catalytic
Vc3S01_2536	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vc3S01_2536	COG1263	PTS System
Vc3S01_2538	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Vc3S01_2539	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Vc3S01_2540	COG2011	ABC-type metal ion transport system permease component
Vc3S01_2541	COG1464	Belongs to the NlpA lipoprotein family
Vc3S01_2543	COG0737	Belongs to the 5'-nucleotidase family
Vc3S01_2544	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
Vc3S01_2548	COG0745	RESPONSE REGULATOR receiver
Vc3S01_2548	COG3706	GGDEF domain
Vc3S01_2549	COG1611	Belongs to the LOG family
Vc3S01_2553	COG2363	Small membrane protein
Vc3S01_2555	COG0583	DNA-binding transcription factor activity
Vc3S01_2558	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Vc3S01_2560	COG0142	geranyltranstransferase activity
Vc3S01_2562	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Vc3S01_2563	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Vc3S01_2568	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Vc3S01_2568	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Vc3S01_2569	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Vc3S01_2570	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Vc3S01_2576	COG2252	PERMEase
Vc3S01_2577	COG2195	Cleaves the N-terminal amino acid of tripeptides
Vc3S01_2582	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Vc3S01_2582	COG0047	phosphoribosylformylglycinamidine synthase activity
Vc3S01_2585	COG0590	tRNA wobble adenosine to inosine editing
Vc3S01_2586	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Vc3S01_2594	COG1301	dicarboxylic acid transport
Vc3S01_2597	COG0497	DNA recombination
Vc3S01_2598	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vc3S01_2599	COG2914	Belongs to the UPF0125 (RnfH) family
Vc3S01_2600	COG2867	negative regulation of translational initiation
Vc3S01_2602	COG0583	DNA-binding transcription factor activity
Vc3S01_2603	COG1289	transmembrane transporter activity
Vc3S01_2607	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Vc3S01_2609	COG1574	metal-dependent hydrolase with the TIM-barrel fold
Vc3S01_2610	COG0668	transmembrane transport
Vc3S01_2614	COG0583	DNA-binding transcription factor activity
Vc3S01_2616	COG1115	amino acid carrier protein
Vc3S01_2617	COG1584	GPR1 FUN34 yaaH family protein
Vc3S01_2619	COG1757	Na H antiporter
Vc3S01_2621	COG0517	IMP dehydrogenase activity
Vc3S01_2621	COG0516	GMP reductase activity
Vc3S01_2624	COG2203	Gaf domain
Vc3S01_2624	COG2199	diguanylate cyclase activity
Vc3S01_2627	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vc3S01_2628	COG2976	Protein conserved in bacteria
Vc3S01_2631	COG1426	Protein conserved in bacteria
Vc3S01_2635	COG2975	iron-sulfur cluster assembly
Vc3S01_2636	COG0633	Ferredoxin
Vc3S01_2639	COG0316	Belongs to the HesB IscA family
Vc3S01_2640	COG0822	iron-sulfur transferase activity
Vc3S01_2643	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
Vc3S01_2644	COG0483	inositol monophosphate 1-phosphatase activity
Vc3S01_2645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vc3S01_2646	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vc3S01_2647	COG1862	Preprotein translocase
Vc3S01_2653	COG0517	IMP dehydrogenase activity
Vc3S01_2655	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Vc3S01_2656	COG0583	DNA-binding transcription factor activity
Vc3S01_2657	COG0450	alkyl hydroperoxide reductase
Vc3S01_2663	COG0704	Plays a role in the regulation of phosphate uptake
Vc3S01_2664	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Vc3S01_2665	COG0581	inorganic phosphate transmembrane transporter activity
Vc3S01_2666	COG0573	inorganic phosphate transmembrane transporter activity
Vc3S01_2667	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Vc3S01_2668	COG0248	Ppx GppA phosphatase
Vc3S01_2670	COG5002	protein histidine kinase activity
Vc3S01_2671	COG0745	RESPONSE REGULATOR receiver
Vc3S01_2674	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Vc3S01_2681	COG0542	response to heat
Vc3S01_2683	COG0564	pseudouridine synthase activity
Vc3S01_2684	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vc3S01_2685	COG0741	lytic transglycosylase activity
Vc3S01_2686	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Vc3S01_2687	COG1605	Chorismate mutase
Vc3S01_2687	COG0077	Prephenate dehydratase
Vc3S01_2688	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
Vc3S01_2691	COG0488	(ABC) transporter
Vc3S01_2693	COG0739	heme binding
Vc3S01_2694	COG0287	Prephenate dehydrogenase
Vc3S01_2694	COG1605	Chorismate mutase
Vc3S01_2695	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Vc3S01_2696	COG1472	Belongs to the glycosyl hydrolase 3 family
Vc3S01_2697	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Vc3S01_2702	COG1966	Carbon starvation protein
Vc3S01_2703	COG3275	phosphorelay sensor kinase activity
Vc3S01_2704	COG3279	Response regulator of the LytR AlgR family
Vc3S01_2705	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Vc3S01_2706	COG1047	Peptidyl-prolyl cis-trans
Vc3S01_2709	COG0196	riboflavin kinase activity
Vc3S01_2710	COG0728	peptidoglycan biosynthetic process
Vc3S01_2711	COG0268	Binds directly to 16S ribosomal RNA
Vc3S01_2712	COG0640	Transcriptional regulator
Vc3S01_2713	COG0583	DNA-binding transcription factor activity
Vc3S01_2714	COG1283	sodium-dependent phosphate transmembrane transporter activity
Vc3S01_2717	COG0730	response to heat
Vc3S01_2722	COG0667	Aldo Keto reductase
Vc3S01_2726	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Vc3S01_2727	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Vc3S01_2728	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vc3S01_2730	COG0716	FMN binding
Vc3S01_2733	COG0513	Belongs to the DEAD box helicase family
Vc3S01_2735	COG3022	response to hydroperoxide
Vc3S01_2736	COG1115	amino acid carrier protein
Vc3S01_2743	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Vc3S01_2744	COG0083	homoserine kinase activity
Vc3S01_2747	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Vc3S01_2749	COG0745	RESPONSE REGULATOR receiver
Vc3S01_2751	COG5002	protein histidine kinase activity
Vc3S01_2751	COG0784	Response regulator, receiver
Vc3S01_2751	COG2198	Histidine kinase
Vc3S01_2752	COG3706	GGDEF domain
Vc3S01_2752	COG5001	Diguanylate cyclase
Vc3S01_2752	COG2203	Gaf domain
Vc3S01_2752	COG4251	negative regulation of phosphorylation
Vc3S01_2753	COG1242	4 iron, 4 sulfur cluster binding
Vc3S01_2754	COG0067	glutamate synthase
Vc3S01_2754	COG0069	glutamate synthase activity
Vc3S01_2754	COG0070	glutamate synthase
Vc3S01_2756	COG0069	glutamate synthase activity
Vc3S01_2756	COG0067	glutamate synthase
Vc3S01_2756	COG0070	glutamate synthase
Vc3S01_2757	COG0493	'glutamate synthase
Vc3S01_2762	COG2860	membrane
Vc3S01_2764	COG0730	response to heat
Vc3S01_2766	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Vc3S01_2767	COG0505	Belongs to the CarA family
Vc3S01_2769	COG0494	nUDIX hydrolase
Vc3S01_2773	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Vc3S01_2774	COG0849	cell division
Vc3S01_2775	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Vc3S01_2778	COG0772	Belongs to the SEDS family
Vc3S01_2781	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Vc3S01_2782	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Vc3S01_2783	COG0768	penicillin binding
Vc3S01_2784	COG3116	cell division
Vc3S01_2786	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Vc3S01_2789	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Vc3S01_2790	COG2823	Periplasmic or secreted lipoprotein
Vc3S01_2791	COG2969	positive regulation of protein catabolic process
Vc3S01_2792	COG0625	glutathione transferase activity
Vc3S01_2793	COG2857	Cytochrome c1
Vc3S01_2794	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Vc3S01_2795	COG0723	plastoquinol--plastocyanin reductase activity
Vc3S01_2798	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Vc3S01_2799	COG3105	Protein conserved in bacteria
Vc3S01_2800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Vc3S01_2801	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Vc3S01_2802	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Vc3S01_2803	COG0187	DNA topoisomerase II activity
Vc3S01_2804	COG3150	esterase
Vc3S01_2806	COG3151	Protein conserved in bacteria
Vc3S01_2807	COG0494	nUDIX hydrolase
Vc3S01_2808	COG1538	Outer membrane efflux protein
Vc3S01_2810	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Vc3S01_2812	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Vc3S01_2813	COG3025	triphosphatase activity
Vc3S01_2814	COG1392	Phosphate transport regulator
Vc3S01_2815	COG0306	phosphate transporter
Vc3S01_2816	COG4991	sh3 domain protein
Vc3S01_2817	COG0405	Gamma-glutamyltransferase
Vc3S01_2819	COG3267	Type II secretory pathway component ExeA
Vc3S01_2819	COG3409	Peptidoglycan-binding domain 1 protein
Vc3S01_2822	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Vc3S01_2823	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Vc3S01_2825	COG0596	Alpha beta hydrolase
Vc3S01_2826	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Vc3S01_2827	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Vc3S01_2828	COG1610	YqeY-like protein
Vc3S01_2829	COG0358	DNA primase activity
Vc3S01_2830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Vc3S01_2836	COG2213	PTS system mannitol-specific
Vc3S01_2836	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vc3S01_2838	COG3722	fumarate hydratase activity
Vc3S01_2839	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Vc3S01_2840	COG5002	protein histidine kinase activity
Vc3S01_2844	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Vc3S01_2845	COG1349	DNA-binding transcription factor activity
Vc3S01_2846	COG0469	pyruvate kinase activity
Vc3S01_2848	COG3706	GGDEF domain
Vc3S01_2849	COG0440	acetolactate synthase activity
Vc3S01_2850	COG0028	Belongs to the TPP enzyme family
Vc3S01_2851	COG1022	Amp-dependent synthetase and ligase
Vc3S01_2852	COG0583	DNA-binding transcription factor activity
Vc3S01_2857	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Vc3S01_2858	COG0473	3-isopropylmalate dehydrogenase activity
Vc3S01_2862	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Vc3S01_2863	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Vc3S01_2864	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vc3S01_2865	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Vc3S01_2870	COG3610	response to peptide
Vc3S01_2871	COG2966	Psort location CytoplasmicMembrane, score
Vc3S01_2874	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Vc3S01_2875	COG0142	geranyltranstransferase activity
Vc3S01_2882	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
Vc3S01_2883	COG1178	ABC-type Fe3 transport system permease component
Vc3S01_2884	COG4143	(ABC) transporter
Vc3S01_2885	COG0163	prenyltransferase activity
Vc3S01_2886	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Vc3S01_2888	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Vc3S01_2891	COG2105	PFAM AIG2 family protein
Vc3S01_2893	COG0729	surface antigen
Vc3S01_2894	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vc3S01_2896	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
Vc3S01_2899	COG1136	(ABC) transporter
Vc3S01_2903	COG0529	Catalyzes the synthesis of activated sulfate
Vc3S01_2904	COG0471	metal ion transport
Vc3S01_2904	COG3273	potassium ion transport
Vc3S01_2907	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Vc3S01_2907	COG1648	precorrin-2 dehydrogenase activity
Vc3S01_2908	COG0737	Belongs to the 5'-nucleotidase family
Vc3S01_2910	COG0513	Belongs to the DEAD box helicase family
Vc3S01_2911	COG2153	protein acetylation
Vc3S01_2914	COG0545	Peptidyl-prolyl cis-trans isomerase
Vc3S01_2916	COG0203	ribosomal protein L17
Vc3S01_2917	COG0202	RNA polymerase activity
Vc3S01_2919	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Vc3S01_2920	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Vc3S01_2922	COG0201	protein transport
Vc3S01_2924	COG1841	ribosomal large subunit assembly
Vc3S01_2941	COG0088	Forms part of the polypeptide exit tunnel
Vc3S01_2945	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Vc3S01_2946	COG1609	Transcriptional regulator
Vc3S01_2950	COG1575	Belongs to the MenA family. Type 1 subfamily
Vc3S01_2951	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Vc3S01_2953	COG1494	fructose-1,6-bisphosphatase
Vc3S01_2958	COG0149	triose-phosphate isomerase activity
Vc3S01_2965	COG1216	Glycosyl transferase, family 2
Vc3S01_2970	COG1215	transferase activity, transferring glycosyl groups
Vc3S01_2971	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Vc3S01_2972	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Vc3S01_2973	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Vc3S01_2975	COG1215	transferase activity, transferring glycosyl groups
Vc3S01_2980	COG2244	polysaccharide biosynthetic process
Vc3S01_2981	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Vc3S01_2991	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vc3S01_2993	COG1560	Kdo2-lipid A biosynthetic process
Vc3S01_2995	COG0438	transferase activity, transferring glycosyl groups
Vc3S01_2996	COG1519	Transferase
Vc3S01_2997	COG1216	Glycosyl transferase, family 2
Vc3S01_2997	COG1442	glycosyl transferase family 8
Vc3S01_2998	COG5039	Polysaccharide pyruvyl transferase
Vc3S01_2999	COG3642	lipopolysaccharide core region biosynthetic process
Vc3S01_3000	COG0859	PFAM glycosyl transferase family 9
Vc3S01_3002	COG0438	transferase activity, transferring glycosyl groups
Vc3S01_3005	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Vc3S01_3012	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Vc3S01_3014	COG1560	Kdo2-lipid A biosynthetic process
Vc3S01_3016	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Vc3S01_3017	COG1561	YicC-like family, N-terminal region
Vc3S01_3021	COG4608	Belongs to the ABC transporter superfamily
Vc3S01_3022	COG0444	Belongs to the ABC transporter superfamily
Vc3S01_3023	COG0747	negative chemotaxis
Vc3S01_3024	COG4239	(ABC) transporter, permease
Vc3S01_3025	COG4174	ABC transporter (Permease)
Vc3S01_3026	COG4206	TonB-dependent receptor
Vc3S01_3029	COG0811	peptide transport
Vc3S01_3030	COG0848	biopolymer transport protein
Vc3S01_3033	COG0194	GDP metabolic process
Vc3S01_3034	COG1758	RNA polymerase activity
Vc3S01_3035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Vc3S01_3036	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Vc3S01_3037	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Vc3S01_3039	COG2233	PERMEase
Vc3S01_3040	COG2205	protein histidine kinase activity
Vc3S01_3041	COG0745	RESPONSE REGULATOR receiver
Vc3S01_3042	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Vc3S01_3044	COG2183	response to ionizing radiation
Vc3S01_3047	COG1040	competence protein
Vc3S01_3049	COG0494	nUDIX hydrolase
Vc3S01_3050	COG1218	3'(2'),5'-bisphosphate nucleotidase
Vc3S01_3052	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
Vc3S01_3053	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
Vc3S01_3054	COG3156	type II secretion system protein K
Vc3S01_3055	COG4795	General secretion pathway protein
Vc3S01_3056	COG2165	general secretion pathway protein
Vc3S01_3057	COG2165	general secretion pathway protein
Vc3S01_3058	COG2165	general secretion pathway protein
Vc3S01_3059	COG1459	type II secretion system
Vc3S01_3060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vc3S01_3062	COG3031	protein transport across the cell outer membrane
Vc3S01_3063	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Vc3S01_3067	COG0456	acetyltransferase
Vc3S01_3068	COG1490	D-aminoacyl-tRNA deacylase activity
Vc3S01_3074	COG0174	glutamine synthetase
Vc3S01_3076	COG3852	Histidine kinase
Vc3S01_3077	COG2204	response regulator
Vc3S01_3078	COG5001	Diguanylate cyclase
Vc3S01_3078	COG3300	MHYT domain
Vc3S01_3079	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Vc3S01_3080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Vc3S01_3086	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Vc3S01_3087	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Vc3S01_3087	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Vc3S01_3091	COG0084	hydrolase, TatD family'
Vc3S01_3094	COG0805	protein transport
Vc3S01_3098	COG3165	ubiquinone biosynthetic process from chorismate
Vc3S01_3100	COG1322	Protein conserved in bacteria
Vc3S01_3103	COG1910	domain protein
Vc3S01_3107	COG2081	HI0933 family
Vc3S01_3109	COG1528	Iron-storage protein
Vc3S01_3110	COG0589	response to stress
Vc3S01_3111	COG0697	spore germination
Vc3S01_3114	COG5002	protein histidine kinase activity
Vc3S01_3114	COG5001	Diguanylate cyclase
Vc3S01_3115	COG1522	sequence-specific DNA binding
Vc3S01_3117	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Vc3S01_3119	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vc3S01_3128	COG3550	peptidyl-serine autophosphorylation
Vc3S01_3134	COG0800	Aldolase
Vc3S01_3135	COG2610	gluconate transmembrane transporter activity
Vc3S01_3136	COG3265	gluconokinase activity
Vc3S01_3137	COG0129	dihydroxy-acid dehydratase activity
Vc3S01_3139	COG2076	Multidrug Resistance protein
Vc3S01_3140	COG0583	DNA-binding transcription factor activity
Vc3S01_3141	COG1609	Transcriptional regulator
Vc3S01_3142	COG0515	serine threonine protein kinase
Vc3S01_3148	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vc3S01_3150	COG4166	transmembrane transport
Vc3S01_3151	COG4172	Belongs to the ABC transporter superfamily
Vc3S01_3155	COG1309	transcriptional regulator
Vc3S01_3156	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vc3S01_3157	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vc3S01_3158	COG2960	long-chain fatty acid transporting porin activity
Vc3S01_3159	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Vc3S01_3160	COG0583	DNA-binding transcription factor activity
Vc3S01_3163	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Vc3S01_3168	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Vc3S01_3169	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Vc3S01_3170	COG0551	DNA topoisomerase type I activity
Vc3S01_3172	COG0758	DNA mediated transformation
Vc3S01_3176	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Vc3S01_3176	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Vc3S01_3177	COG0569	domain protein
Vc3S01_3178	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vc3S01_3180	COG1272	protein, Hemolysin III
Vc3S01_3181	COG4326	sporulation control protein
Vc3S01_3184	COG3084	Protein conserved in bacteria
Vc3S01_3186	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Vc3S01_3187	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vc3S01_3189	COG0204	Acyl-transferase
Vc3S01_3191	COG2199	diguanylate cyclase activity
Vc3S01_3192	COG0606	chelatase, subunit chli
Vc3S01_3194	COG3978	acetolactate synthase activity
Vc3S01_3195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Vc3S01_3196	COG0129	dihydroxy-acid dehydratase activity
Vc3S01_3198	COG3706	GGDEF domain
Vc3S01_3199	COG0583	DNA-binding transcription factor activity
Vc3S01_3200	COG2814	Major facilitator Superfamily
Vc3S01_3201	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vc3S01_3202	COG0765	amino acid transport
Vc3S01_3204	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Vc3S01_3206	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Vc3S01_3212	COG3312	ion transport
Vc3S01_3213	COG1475	DNA binding
Vc3S01_3214	COG1192	Involved in chromosome partitioning
Vc3S01_A0005	COG4608	Belongs to the ABC transporter superfamily
Vc3S01_A0006	COG0444	Belongs to the ABC transporter superfamily
Vc3S01_A0008	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
Vc3S01_A0008	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Vc3S01_A0013	COG0772	Belongs to the SEDS family
Vc3S01_A0016	COG1566	PFAM secretion protein HlyD family protein
Vc3S01_A0017	COG0583	DNA-binding transcription factor activity
Vc3S01_A0019	COG1136	(ABC) transporter
Vc3S01_A0023	COG3275	phosphorelay sensor kinase activity
Vc3S01_A0024	COG3279	Response regulator of the LytR AlgR family
Vc3S01_A0026	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Vc3S01_A0030	COG0786	glutamate:sodium symporter activity
Vc3S01_A0031	COG1028	Short-chain dehydrogenase reductase Sdr
Vc3S01_A0038	COG1131	(ABC) transporter
Vc3S01_A0039	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vc3S01_A0040	COG0786	glutamate:sodium symporter activity
Vc3S01_A0044	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vc3S01_A0046	COG2207	Transcriptional regulator
Vc3S01_A0046	COG1609	Transcriptional regulator
Vc3S01_A0053	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Vc3S01_A0055	COG2207	Transcriptional regulator
Vc3S01_A0056	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Vc3S01_A0058	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vc3S01_A0060	COG0659	secondary active sulfate transmembrane transporter activity
Vc3S01_A0063	COG0251	oxidation-reduction process
Vc3S01_A0064	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Vc3S01_A0075	COG2259	Doxx family
Vc3S01_A0077	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Vc3S01_A0078	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Vc3S01_A0080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Vc3S01_A0091	COG5001	Diguanylate cyclase
Vc3S01_A0094	COG1609	Transcriptional regulator
Vc3S01_A0097	COG0395	ABC-type sugar transport system, permease component
Vc3S01_A0098	COG2723	6-phospho-beta-galactosidase activity
Vc3S01_A0099	COG3842	ATPase activity
Vc3S01_A0100	COG1609	Transcriptional regulator
Vc3S01_A0104	COG0747	negative chemotaxis
Vc3S01_A0106	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vc3S01_A0107	COG0444	Belongs to the ABC transporter superfamily
Vc3S01_A0108	COG4608	Belongs to the ABC transporter superfamily
Vc3S01_A0110	COG1609	Transcriptional regulator
Vc3S01_A0115	COG1472	Belongs to the glycosyl hydrolase 3 family
Vc3S01_A0116	COG0534	Mate efflux family protein
Vc3S01_A0117	COG0564	pseudouridine synthase activity
Vc3S01_A0118	COG0561	phosphatase activity
Vc3S01_A0122	COG3152	Membrane
Vc3S01_A0125	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Vc3S01_A0129	COG0583	DNA-binding transcription factor activity
Vc3S01_A0139	COG2076	Multidrug Resistance protein
Vc3S01_A0142	COG0534	Mate efflux family protein
Vc3S01_A0145	COG1357	PFAM Pentapeptide repeats (8 copies)
Vc3S01_A0146	COG3047	cAMP biosynthetic process
Vc3S01_A0152	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
Vc3S01_A0152	COG3408	Glycogen debranching enzyme
Vc3S01_A0171	COG3835	regulator
Vc3S01_A0172	COG1929	Belongs to the glycerate kinase type-1 family
Vc3S01_A0173	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vc3S01_A0181	COG0456	acetyltransferase
Vc3S01_A0185	COG1028	Short-chain dehydrogenase reductase Sdr
Vc3S01_A0187	COG3005	denitrification pathway
Vc3S01_A0188	COG0243	molybdopterin cofactor binding
Vc3S01_A0189	COG0671	phosphoesterase, PA-phosphatase related
Vc3S01_A0192	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Vc3S01_A0193	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Vc3S01_A0194	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Vc3S01_A0195	COG1116	anion transmembrane transporter activity
Vc3S01_A0196	COG0351	phosphomethylpyrimidine kinase
Vc3S01_A0197	COG0312	modulator of DNA gyrase
Vc3S01_A0198	COG0312	modulator of DNA gyrase
Vc3S01_A0204	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Vc3S01_A0206	COG0584	glycerophosphoryl diester phosphodiesterase
Vc3S01_A0208	COG0745	RESPONSE REGULATOR receiver
Vc3S01_A0212	COG0811	peptide transport
Vc3S01_A0213	COG0811	peptide transport
Vc3S01_A0214	COG0848	biopolymer transport protein
Vc3S01_A0223	COG0803	Belongs to the bacterial solute-binding protein 9 family
Vc3S01_A0224	COG1121	(ABC) transporter
Vc3S01_A0225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Vc3S01_A0228	COG1770	oligopeptidase
Vc3S01_A0229	COG2814	Major facilitator Superfamily
Vc3S01_A0230	COG0010	Belongs to the arginase family
Vc3S01_A0231	COG1166	arginine decarboxylase activity
Vc3S01_A0233	COG4067	protein conserved in archaea
Vc3S01_A0233	COG0189	ligase activity
Vc3S01_A0234	COG0189	ligase activity
Vc3S01_A0236	COG0583	DNA-binding transcription factor activity
Vc3S01_A0245	COG1114	Component of the transport system for branched-chain amino acids
Vc3S01_A0249	COG0579	oxidoreductase
Vc3S01_A0253	COG3033	Beta-eliminating lyase
Vc3S01_A0257	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Vc3S01_A0258	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Vc3S01_A0266	COG3706	GGDEF domain
Vc3S01_A0267	COG0415	Belongs to the DNA photolyase family
Vc3S01_A0268	COG3046	protein related to deoxyribodipyrimidine photolyase
Vc3S01_A0270	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vc3S01_A0270	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vc3S01_A0271	COG1765	OsmC-like protein
Vc3S01_A0278	COG1011	Hydrolase
Vc3S01_A0284	COG3240	lipase activity
Vc3S01_A0291	COG1840	ABC-type Fe3 transport system, periplasmic component
Vc3S01_A0292	COG3842	ATPase activity
Vc3S01_A0297	COG2990	Protein conserved in bacteria
Vc3S01_A0299	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Vc3S01_A0300	COG2866	Carboxypeptidase
Vc3S01_A0302	COG0583	DNA-binding transcription factor activity
Vc3S01_A0308	COG1760	l-serine dehydratase
Vc3S01_A0313	COG1388	LysM domain
Vc3S01_A0313	COG0741	lytic transglycosylase activity
Vc3S01_A0317	COG1815	bacterial-type flagellum-dependent cell motility
Vc3S01_A0318	COG1558	bacterial-type flagellum-dependent cell motility
Vc3S01_A0319	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Vc3S01_A0320	COG1749	Flagellar hook protein flgE
Vc3S01_A0321	COG4787	bacterial-type flagellum-dependent cell motility
Vc3S01_A0322	COG4786	Flagellar basal body rod
Vc3S01_A0323	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Vc3S01_A0324	COG1706	bacterial-type flagellum-dependent cell motility
Vc3S01_A0326	COG1256	bacterial-type flagellum assembly
Vc3S01_A0326	COG4786	Flagellar basal body rod
Vc3S01_A0327	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vc3S01_A0344	COG0384	phenazine biosynthesis protein PhzF
Vc3S01_A0349	COG1360	Flagellar Motor Protein
Vc3S01_A0350	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Vc3S01_A0351	COG1191	sigma factor activity
Vc3S01_A0352	COG1580	Controls the rotational direction of flagella during chemotaxis
Vc3S01_A0355	COG1516	flagellar protein fliS
Vc3S01_A0356	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Vc3S01_A0358	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vc3S01_A0361	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Vc3S01_A0363	COG1987	bacterial-type flagellum assembly
Vc3S01_A0368	COG2204	response regulator
Vc3S01_A0371	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Vc3S01_A0375	COG2200	EAL domain
Vc3S01_A0380	COG3121	Chaperone
Vc3S01_A0383	COG3121	Chaperone
Vc3S01_A0393	COG0346	lactoylglutathione lyase activity
Vc3S01_A0398	COG0745	RESPONSE REGULATOR receiver
Vc3S01_A0403	COG0156	8-amino-7-oxononanoate synthase activity
Vc3S01_A0404	COG1063	alcohol dehydrogenase
Vc3S01_A0410	COG2203	Gaf domain
Vc3S01_A0410	COG2199	diguanylate cyclase activity
Vc3S01_A0411	COG2223	nitrite transmembrane transporter activity
Vc3S01_A0412	COG1063	alcohol dehydrogenase
Vc3S01_A0414	COG0668	transmembrane transport
Vc3S01_A0416	COG1304	FMN binding
Vc3S01_A0417	COG1620	l-lactate permease
Vc3S01_A0418	COG0583	DNA-binding transcription factor activity
Vc3S01_A0419	COG1505	serine-type exopeptidase activity
Vc3S01_A0420	COG4172	Belongs to the ABC transporter superfamily
Vc3S01_A0422	COG1067	ATP-dependent peptidase activity
Vc3S01_A0424	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vc3S01_A0428	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vc3S01_A0429	COG0437	4 iron, 4 sulfur cluster binding
Vc3S01_A0430	COG0348	domain, Protein
Vc3S01_A0436	COG1122	ATPase activity
Vc3S01_A0438	COG1566	PFAM secretion protein HlyD family protein
Vc3S01_A0441	COG3706	GGDEF domain
Vc3S01_A0444	COG0813	purine-nucleoside phosphorylase activity
Vc3S01_A0445	COG3272	Protein of unknown function (DUF1722)
Vc3S01_A0446	COG0789	Transcriptional regulator
Vc3S01_A0447	COG0415	Belongs to the DNA photolyase family
Vc3S01_A0448	COG1376	ErfK ybiS ycfS ynhG family protein
Vc3S01_A0448	COG1388	LysM domain
Vc3S01_A0450	COG0513	Belongs to the DEAD box helicase family
Vc3S01_A0453	COG1770	oligopeptidase
Vc3S01_A0454	COG4771	TonB-dependent receptor
Vc3S01_A0458	COG0840	transmembrane signaling receptor activity
Vc3S01_A0459	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Vc3S01_A0460	COG0573	inorganic phosphate transmembrane transporter activity
Vc3S01_A0461	COG0581	inorganic phosphate transmembrane transporter activity
Vc3S01_A0465	COG2304	oxidoreductase activity
Vc3S01_A0469	COG0714	Associated with various cellular activities
Vc3S01_A0475	COG2197	response regulator
Vc3S01_A0481	COG0110	maltose O-acetyltransferase activity
Vc3S01_A0483	COG4191	Histidine kinase
Vc3S01_A0484	COG1028	Short-chain dehydrogenase reductase Sdr
Vc3S01_A0487	COG2885	chlorophyll binding
Vc3S01_A0487	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Vc3S01_A0495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Vc3S01_A0496	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
Vc3S01_A0498	COG1252	NADH dehydrogenase
Vc3S01_A0499	COG1301	dicarboxylic acid transport
Vc3S01_A0509	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vc3S01_A0509	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vc3S01_A0509	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vc3S01_A0510	COG2207	Transcriptional regulator
Vc3S01_A0512	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vc3S01_A0513	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vc3S01_A0514	COG0583	DNA-binding transcription factor activity
Vc3S01_A0516	COG2084	Dehydrogenase
Vc3S01_A0517	COG0753	catalase activity
Vc3S01_A0519	COG2130	NADP-dependent
Vc3S01_A0520	COG1309	transcriptional regulator
Vc3S01_A0529	COG3206	protein involved in exopolysaccharide biosynthesis
Vc3S01_A0529	COG0489	protein tyrosine kinase activity
Vc3S01_A0532	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Vc3S01_A0533	COG2200	EAL domain
Vc3S01_A0535	COG3842	ATPase activity
Vc3S01_A0537	COG1175	transmembrane transport
Vc3S01_A0544	COG2354	Protein conserved in bacteria
Vc3S01_A0546	COG0401	homolog of Blt101
Vc3S01_A0547	COG3217	Mosc domain protein beta barrel domain protein
Vc3S01_A0547	COG3217	Mosc domain protein beta barrel domain protein
Vc3S01_A0547	COG0633	Ferredoxin
Vc3S01_A0547	COG0633	Ferredoxin
Vc3S01_A0549	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Vc3S01_A0558	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Vc3S01_A0559	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vc3S01_A0561	COG0848	biopolymer transport protein
Vc3S01_A0562	COG0811	peptide transport
Vc3S01_A0563	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
Vc3S01_A0565	COG3721	Heme iron utilization protein
Vc3S01_A0566	COG0748	coenzyme F420 binding
Vc3S01_A0569	COG0784	Response regulator, receiver
Vc3S01_A0569	COG0835	chemotaxis
Vc3S01_A0570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vc3S01_A0571	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Vc3S01_A0572	COG0366	Alpha amylase catalytic
Vc3S01_A0575	COG0583	DNA-binding transcription factor activity
Vc3S01_A0581	COG0583	DNA-binding transcription factor activity
Vc3S01_A0584	COG2249	NAD(P)H dehydrogenase (quinone) activity
Vc3S01_A0585	COG0583	DNA-binding transcription factor activity
Vc3S01_A0592	COG4977	sequence-specific DNA binding
Vc3S01_A0593	COG0673	inositol 2-dehydrogenase activity
Vc3S01_A0595	COG2194	sulfuric ester hydrolase activity
Vc3S01_A0596	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Vc3S01_A0598	COG2205	protein histidine kinase activity
Vc3S01_A0599	COG0745	RESPONSE REGULATOR receiver
Vc3S01_A0603	COG4221	oxidoreductase activity
Vc3S01_A0606	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vc3S01_A0610	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Vc3S01_A0612	COG2814	Major facilitator Superfamily
Vc3S01_A0615	COG1418	mRNA catabolic process
Vc3S01_A0618	COG0402	S-adenosylhomocysteine deaminase activity
Vc3S01_A0619	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Vc3S01_A0620	COG2239	Acts as a magnesium transporter
Vc3S01_A0621	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Vc3S01_A0622	COG1566	PFAM secretion protein HlyD family protein
Vc3S01_A0623	COG3941	tape measure
Vc3S01_A0627	COG4397	Mu-like prophage major head subunit gpT
Vc3S01_A0643	COG0745	RESPONSE REGULATOR receiver
Vc3S01_A0644	COG2205	protein histidine kinase activity
Vc3S01_A0646	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vc3S01_A0647	COG0531	amino acid
Vc3S01_A0650	COG0583	DNA-binding transcription factor activity
Vc3S01_A0656	COG0784	Response regulator, receiver
Vc3S01_A0656	COG2205	protein histidine kinase activity
Vc3S01_A0656	COG5002	protein histidine kinase activity
Vc3S01_A0657	COG0673	inositol 2-dehydrogenase activity
Vc3S01_A0659	COG3423	Transcriptional regulator
Vc3S01_A0660	COG2801	Transposase and inactivated derivatives
Vc3S01_A0661	COG2842	Transposition protein
Vc3S01_A0682	COG0640	Transcriptional regulator
Vc3S01_A0686	COG4373	Mu-like prophage FluMu protein gp28
Vc3S01_A0687	COG4383	Mu-like prophage protein gp29
Vc3S01_A0691	COG4397	Mu-like prophage major head subunit gpT
Vc3S01_A0695	COG4387	Mu-like prophage protein GP36
Vc3S01_A0699	COG4386	tail sheath protein
Vc3S01_A0701	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
Vc3S01_A0707	COG3299	homolog of phage Mu protein gp47
Vc3S01_A0708	COG3778	Protein conserved in bacteria
Vc3S01_A0726	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vc3S01_A0727	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vc3S01_A0729	COG1280	lysine exporter protein (LysE YggA)
Vc3S01_A0731	COG0183	Belongs to the thiolase family
Vc3S01_A0735	COG3005	denitrification pathway
Vc3S01_A0739	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Vc3S01_A0740	COG3850	Histidine kinase
Vc3S01_A0741	COG2197	response regulator
Vc3S01_A0744	COG2195	Cleaves the N-terminal amino acid of tripeptides
Vc3S01_A0749	COG0840	transmembrane signaling receptor activity
Vc3S01_A0751	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Vc3S01_A0752	COG0545	Peptidyl-prolyl cis-trans isomerase
Vc3S01_A0758	COG1278	Cold shock
Vc3S01_A0759	COG3036	rescue of stalled ribosome
Vc3S01_A0761	COG2199	diguanylate cyclase activity
Vc3S01_A0765	COG1136	(ABC) transporter
Vc3S01_A0767	COG0840	transmembrane signaling receptor activity
Vc3S01_A0768	COG0783	Belongs to the Dps family
Vc3S01_A0770	COG1619	proteins homologs of microcin C7 resistance protein MccF
Vc3S01_A0771	COG2133	pyrroloquinoline quinone binding
Vc3S01_A0772	COG1454	alcohol dehydrogenase
Vc3S01_A0773	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
Vc3S01_A0778	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Vc3S01_A0780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Vc3S01_A0781	COG3186	Phenylalanine-4-hydroxylase
Vc3S01_A0788	COG3530	Putative quorum-sensing-regulated virulence factor
Vc3S01_A0794	COG0523	cobalamin synthesis protein
Vc3S01_A0796	COG5002	protein histidine kinase activity
Vc3S01_A0796	COG3447	MASE1 domain protein
Vc3S01_A0796	COG5001	Diguanylate cyclase
Vc3S01_A0797	COG0513	Belongs to the DEAD box helicase family
Vc3S01_A0801	COG2200	EAL domain
Vc3S01_A0802	COG1119	ATPase activity
Vc3S01_A0809	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Vc3S01_A0812	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
Vc3S01_A0813	COG0513	Belongs to the DEAD box helicase family
Vc3S01_A0815	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Vc3S01_A0832	COG2182	Extracellular solute-binding protein
Vc3S01_A0833	COG1175	transmembrane transport
Vc3S01_A0834	COG3833	ABC-type maltose transport systems, permease component
Vc3S01_A0836	COG1874	Beta-galactosidase
Vc3S01_A0837	COG4580	involved in the transport of maltose and maltodextrins
Vc3S01_A0838	COG0840	transmembrane signaling receptor activity
Vc3S01_A0839	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Vc3S01_A0849	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Vc3S01_A0850	COG3550	peptidyl-serine autophosphorylation
Vc3S01_A0855	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Vc3S01_A0857	COG1752	Esterase of the alpha-beta hydrolase superfamily
Vc3S01_A0861	COG3278	Belongs to the heme-copper respiratory oxidase family
Vc3S01_A0871	COG1024	Enoyl-CoA hydratase
Vc3S01_A0872	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Vc3S01_A0873	COG1960	acyl-CoA dehydrogenase activity
Vc3S01_A0875	COG0183	Belongs to the thiolase family
Vc3S01_A0878	COG1024	Enoyl-CoA hydratase
Vc3S01_A0879	COG1024	Enoyl-CoA hydratase
Vc3S01_A0882	COG1028	Short-chain dehydrogenase reductase Sdr
Vc3S01_A0884	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Vc3S01_A0885	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Vc3S01_A0886	COG1845	cytochrome c oxidase, subunit III
Vc3S01_A0887	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Vc3S01_A0889	COG1902	pentaerythritol trinitrate reductase activity
Vc3S01_A0889	COG0446	pyridine nucleotide-disulphide oxidoreductase
Vc3S01_A0892	COG1012	belongs to the aldehyde dehydrogenase family
Vc3S01_A0894	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vc3S01_A0905	COG1126	abc transporter atp-binding protein
Vc3S01_A0906	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vc3S01_A0907	COG4215	(ABC) transporter
Vc3S01_A0908	COG4160	amino acid transport
Vc3S01_A0914	COG2200	EAL domain
Vc3S01_A0924	COG0443	Heat shock 70 kDa protein
Vc3S01_A0932	COG0745	RESPONSE REGULATOR receiver
Vc3S01_A0935	COG1785	Belongs to the alkaline phosphatase family
Vc3S01_A0939	COG3706	GGDEF domain
Vc3S01_A0941	COG0814	amino acid
Vc3S01_A0942	COG5001	Diguanylate cyclase
Vc3S01_A0942	COG5002	protein histidine kinase activity
Vc3S01_A0945	COG0243	molybdopterin cofactor binding
Vc3S01_A0946	COG1648	precorrin-2 dehydrogenase activity
Vc3S01_A0946	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Vc3S01_A0950	COG1116	anion transmembrane transporter activity
Vc3S01_A0950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Vc3S01_A0951	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Vc3S01_A0952	COG1116	anion transmembrane transporter activity
Vc3S01_A0953	COG2146	nitrite reductase [NAD(P)H] activity
Vc3S01_A0953	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Vc3S01_A0961	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Vc3S01_A0963	COG1902	pentaerythritol trinitrate reductase activity
Vc3S01_A0966	COG0739	heme binding
Vc3S01_A0972	COG0628	permease
Vc3S01_A0973	COG3706	GGDEF domain
Vc3S01_A0973	COG0745	RESPONSE REGULATOR receiver
Vc3S01_A0988	COG2814	Major facilitator Superfamily
Vc3S01_A0997	COG1132	(ABC) transporter
Vc3S01_A0999	COG5640	endopeptidase activity
Vc3S01_A1003	COG0583	DNA-binding transcription factor activity
Vc3S01_A1008	COG3119	arylsulfatase activity
Vc3S01_A1010	COG0641	radical SAM
Vc3S01_A1014	COG4977	sequence-specific DNA binding
Vc3S01_A1024	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Vc3S01_A1027	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Vc3S01_A1029	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vc3S01_A1030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vc3S01_A1033	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
Vc3S01_A1033	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vc3S01_A1033	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vc3S01_A1034	COG1105	Belongs to the carbohydrate kinase PfkB family
Vc3S01_A1035	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vc3S01_A1035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vc3S01_A1036	COG1609	Transcriptional regulator
Vc3S01_A1039	COG2199	diguanylate cyclase activity
Vc3S01_A1039	COG2200	EAL domain
Vc3S01_A1039	COG2203	Gaf domain
Vc3S01_A1040	COG0765	amino acid transport
Vc3S01_A1041	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vc3S01_A1042	COG0765	amino acid transport
Vc3S01_A1043	COG1126	abc transporter atp-binding protein
Vc3S01_A1045	COG1979	alcohol dehydrogenase
Vc3S01_A1046	COG2207	Transcriptional regulator
Vc3S01_A1048	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Vc3S01_A1050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vc3S01_A1053	COG0784	Response regulator, receiver
Vc3S01_A1053	COG3437	response regulator, receiver
Vc3S01_A1054	COG0546	phosphoglycolate phosphatase activity
Vc3S01_A1057	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
Vc3S01_A1058	COG0513	Belongs to the DEAD box helicase family
Vc3S01_A1059	COG4943	cyclic-guanylate-specific phosphodiesterase activity
Vc3S01_A1062	COG3038	cytochrome b561
Vc3S01_A1064	COG2116	formate transmembrane transporter activity
Vc3S01_A1065	COG0583	DNA-binding transcription factor activity
Vc3S01_A1067	COG3593	DNA synthesis involved in DNA repair
Vc3S01_A1068	COG0737	Belongs to the 5'-nucleotidase family
Vc3S01_A1071	COG1410	methionine synthase
Vc3S01_A1071	COG0646	methionine synthase
Vc3S01_A1074	COG2267	carboxylic ester hydrolase activity
Vc3S01_A1075	COG2067	long-chain fatty acid transport protein
Vc3S01_A1077	COG0501	Belongs to the peptidase M48B family
Vc3S01_A1078	COG2050	protein possibly involved in aromatic compounds catabolism
Vc3S01_A1085	COG0484	heat shock protein binding
Vc3S01_A1087	COG3300	MHYT domain
Vc3S01_A1087	COG5001	Diguanylate cyclase
Vc3S01_A1088	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Vc3S01_A1090	COG4181	ATPase activity
Vc3S01_A1091	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
Vc3S01_A1093	COG1984	allophanate hydrolase subunit 2
Vc3S01_A1094	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Vc3S01_A1096	COG3447	MASE1 domain protein
Vc3S01_A1096	COG5001	Diguanylate cyclase
Vc3S01_A1096	COG5002	protein histidine kinase activity
Vc3S01_A1097	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Vc3S01_A1100	COG0583	DNA-binding transcription factor activity
Vc3S01_A1101	COG0045	succinate-CoA ligase (ADP-forming) activity
Vc3S01_A1101	COG1042	CoA-binding domain protein
Vc3S01_A1101	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vc3S01_A1105	COG0023	Translation Initiation Factor
Vc3S01_A1106	COG2801	Transposase and inactivated derivatives
Vc3S01_A1112	COG3140	Belongs to the UPF0181 family
Vc3S01_A1117	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Vc3S01_A1118	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Vc3S01_A1121	COG0745	RESPONSE REGULATOR receiver
Vc3S01_A1121	COG3706	GGDEF domain
Vc3S01_A1122	COG5001	Diguanylate cyclase
Vc3S01_A1122	COG4251	negative regulation of phosphorylation
Vc3S01_A1122	COG3706	GGDEF domain
Vc3S01_A1122	COG2203	Gaf domain
Vc3S01_A1124	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Vc3S01_A1125	COG4149	molybdate abc transporter
Vc3S01_A1126	COG0725	ABC transporter, periplasmic molybdate-binding protein
Vc3S01_A1128	COG3111	PFAM Bacterial OB fold (BOF) protein
Vc3S01_A1133	COG0534	Mate efflux family protein
Vc3S01_A1134	COG0602	queuosine metabolic process
Vc3S01_A1135	COG1328	CTP reductase activity
Vc3S01_A1147	COG2197	response regulator
Vc3S01_A1148	COG3851	Histidine kinase
Vc3S01_A1149	COG2271	Major facilitator Superfamily
Vc3S01_A1150	COG1482	cell wall glycoprotein biosynthetic process
Vc3S01_A1152	COG0628	permease
Vc3S01_A1154	COG1566	PFAM secretion protein HlyD family protein
Vc3S01_A1161	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Vc3S01_A1162	COG3118	belongs to the thioredoxin family
Vc3S01_A1163	COG2814	Major facilitator Superfamily
Vc3S01_A1165	COG0534	Mate efflux family protein
Vc3S01_A1170	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Vc3S01_A1174	COG2116	formate transmembrane transporter activity
Vc3S01_A1175	COG2146	nitrite reductase [NAD(P)H] activity
Vc3S01_A1176	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Vc3S01_A1178	COG2199	diguanylate cyclase activity
Vc3S01_A1187	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vc3S01_A1189	COG0277	FAD linked oxidase domain protein
Vc3S01_A1190	COG0583	DNA-binding transcription factor activity
Vc3S01_A1192	COG2425	protein containing a von Willebrand factor type A (vWA) domain
Vc3S01_A1195	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
Vc3S01_A1197	COG1288	antiporter activity
Vc3S01_A1200	COG2814	Major facilitator Superfamily
Vc3S01_A1202	COG3040	lipid binding
Vc3S01_A1208	COG3469	chitinase activity
Vc3S01_A1210	COG0419	ATPase involved in DNA repair
Vc3S01_A1211	COG0420	3'-5' exonuclease activity
Vc3S01_A1214	COG3209	COG3209 Rhs family protein
Vc3S01_A1216	COG3501	Rhs element vgr protein
Vc3S01_A1227	COG0631	protein serine/threonine phosphatase activity
Vc3S01_A1234	COG2815	serine threonine protein kinase
Vc3S01_A1234	COG0515	serine threonine protein kinase
Vc3S01_A1240	COG0346	lactoylglutathione lyase activity
Vc3S01_A1241	COG1902	pentaerythritol trinitrate reductase activity
Vc3S01_A1243	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Vc3S01_A1243	COG2755	lipolytic protein G-D-S-L family
Vc3S01_A1246	COG0069	glutamate synthase activity
Vc3S01_A1246	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Vc3S01_A1248	COG1234	tRNA 3'-trailer cleavage
Vc3S01_A1249	COG2067	long-chain fatty acid transport protein
Vc3S01_A1257	COG2076	Multidrug Resistance protein
Vc3S01_A1261	COG0671	phosphoesterase, PA-phosphatase related
Vc3S01_A1264	COG2962	Rard protein
Vc3S01_A1267	COG0784	Response regulator, receiver
Vc3S01_A1267	COG0835	chemotaxis
Vc3S01_A1268	COG0778	Nitroreductase
Vc3S01_A1269	COG2197	response regulator
Vc3S01_A1271	COG3706	GGDEF domain
Vc3S01_A1272	COG2197	response regulator
Vc3S01_A1273	COG5001	Diguanylate cyclase
Vc3S01_A1273	COG3300	MHYT domain
Vc3S01_A1274	COG0784	Response regulator, receiver
Vc3S01_A1274	COG2205	protein histidine kinase activity
Vc3S01_A1277	COG4771	TonB-dependent receptor
Vc3S01_A1291	COG1522	sequence-specific DNA binding
Vc3S01_A1298	COG0515	serine threonine protein kinase
Vc3S01_A1303	COG3501	Rhs element vgr protein
Vc3S01_A1312	COG0739	heme binding
Vc3S01_A1313	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Vc3S01_A1319	COG3069	C4-dicarboxylate transmembrane transporter activity
Vc3S01_A1320	COG1704	LemA family
Vc3S01_A1321	COG0501	Belongs to the peptidase M48B family
Vc3S01_A1326	COG0641	radical SAM
Vc3S01_A1330	COG3111	PFAM Bacterial OB fold (BOF) protein
Vc3S01_A1331	COG1597	lipid kinase activity
Vc3S01_A1332	COG0583	DNA-binding transcription factor activity
Vc3S01_A1334	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Vc3S01_A1336	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Vc3S01_A1348	COG0714	Associated with various cellular activities
Vc3S01_A1349	COG3063	Type IV pilus biogenesis stability protein PilW
Vc3S01_A1350	COG3119	arylsulfatase activity
Vc3S01_A1351	COG3119	arylsulfatase activity
Vc3S01_A1357	COG0784	Response regulator, receiver
Vc3S01_A1357	COG2198	Histidine kinase
Vc3S01_A1357	COG2205	protein histidine kinase activity
Vc3S01_A1358	COG1879	ABC-type sugar transport system periplasmic component
Vc3S01_A1360	COG0210	DNA helicase
Vc3S01_A1361	COG1289	transmembrane transporter activity
Vc3S01_A1367	COG0789	Transcriptional regulator
Vc3S01_A1368	COG4604	ABC transporter, ATP-binding protein
Vc3S01_A1369	COG4605	iron ion homeostasis
Vc3S01_A1370	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vc3S01_A1371	COG4607	ABC-type enterochelin transport system periplasmic component
Vc3S01_A1374	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
Vc3S01_A1377	COG1609	Transcriptional regulator
Vc3S01_A1378	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vc3S01_A1379	COG1879	ABC-type sugar transport system periplasmic component
Vc3S01_A1380	COG1172	Belongs to the binding-protein-dependent transport system permease family
Vc3S01_A1381	COG1129	ABC transporter
Vc3S01_A1383	COG5001	Diguanylate cyclase
Vc3S01_A1384	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Vc3S01_A1387	COG1794	racemase activity, acting on amino acids and derivatives
Vc3S01_A1388	COG1051	belongs to the nudix hydrolase family
Vc3S01_A1393	COG0586	Pfam SNARE associated Golgi protein
Vc3S01_A1401	COG2205	protein histidine kinase activity
Vc3S01_A1401	COG0784	Response regulator, receiver
Vc3S01_A1404	COG4251	negative regulation of phosphorylation
Vc3S01_A1404	COG2203	Gaf domain
Vc3S01_A1404	COG3706	GGDEF domain
Vc3S01_A1404	COG5001	Diguanylate cyclase
Vc3S01_A1405	COG2197	response regulator
Vc3S01_A1408	COG0330	HflC and HflK could
Vc3S01_A1410	COG0517	IMP dehydrogenase activity
Vc3S01_A1410	COG4175	Glycine betaine
Vc3S01_A1411	COG4176	ABC-type proline glycine betaine transport system permease component
Vc3S01_A1416	COG3706	GGDEF domain
Vc3S01_A1424	COG2885	chlorophyll binding
Vc3S01_A1432	COG0455	bacterial-type flagellum organization
Vc3S01_A1434	COG4964	Belongs to the GSP D family
Vc3S01_A1438	COG0583	DNA-binding transcription factor activity
Vc3S01_A1439	COG1073	alpha beta
Vc3S01_A1443	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Vc3S01_A1443	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Vc3S01_A1446	COG4989	oxidoreductase activity
Vc3S01_A1451	COG1914	H( )-stimulated, divalent metal cation uptake system
Vc3S01_A1456	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Vc3S01_A1467	COG2897	thiosulfate sulfurtransferase activity
Vc3S01_A1472	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Vc3S01_A1475	COG2814	Major facilitator Superfamily
Vc3S01_A1476	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Vc3S01_A1479	COG1612	heme a metabolic process
Vc3S01_A1484	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
Vc3S01_A1485	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Vc3S01_A1487	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Vc3S01_A1489	COG1280	lysine exporter protein (LysE YggA)
Vc3S01_A1493	COG0179	Fumarylacetoacetate (FAA) hydrolase
Vc3S01_A1496	COG0697	spore germination
Vc3S01_A1500	COG2814	Major facilitator Superfamily
Vc3S01_A1501	COG0583	DNA-binding transcription factor activity
Vc3S01_A1502	COG5001	Diguanylate cyclase
Vc3S01_A1503	COG0739	heme binding
Vc3S01_A1510	COG0814	amino acid
Vc3S01_A1514	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Vc3S01_A1515	COG1072	(Pantothenic acid kinase))
Vc3S01_A1517	COG1063	alcohol dehydrogenase
Vc3S01_A1518	COG2213	PTS system mannitol-specific
Vc3S01_A1519	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vc3S01_A1520	COG0747	negative chemotaxis
Vc3S01_A1523	COG1733	regulation of RNA biosynthetic process
Vc3S01_A1526	COG0798	PFAM Bile acid sodium symporter
Vc3S01_A1529	COG1881	PFAM PEBP family protein
Vc3S01_A1530	COG0251	oxidation-reduction process
Vc3S01_A1531	COG2706	6-phosphogluconolactonase activity
Vc3S01_A1533	COG0800	Aldolase
Vc3S01_A1534	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vc3S01_A1535	COG4145	pantothenate transmembrane transporter activity
Vc3S01_A1537	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Vc3S01_A1542	COG1131	(ABC) transporter
Vc3S01_A1543	COG0842	Transport permease protein
Vc3S01_A1547	COG3383	formate dehydrogenase (NAD+) activity
Vc3S01_A1551	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vc3S01_A1560	COG0494	nUDIX hydrolase
Vc3S01_A1563	COG1858	cytochrome C peroxidase
Vc3S01_A1565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vc3S01_A1567	COG2067	long-chain fatty acid transport protein
Vc3S01_A1570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vc3S01_A1572	COG1505	serine-type exopeptidase activity
Vc3S01_A1573	COG0488	(ABC) transporter
Vc3S01_A1576	COG0589	response to stress
Vc3S01_A1578	COG0584	glycerophosphoryl diester phosphodiesterase
Vc3S01_A1580	COG1175	transmembrane transport
Vc3S01_A1581	COG0395	ABC-type sugar transport system, permease component
Vc3S01_A1582	COG3842	ATPase activity
Vc3S01_A1587	COG1846	Transcriptional regulator
Vc3S01_A1589	COG0523	cobalamin synthesis protein
Vc3S01_A1591	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Vc3S01_A1593	COG4667	esterase of the alpha-beta hydrolase superfamily
Vc3S01_A1595	COG1741	Belongs to the pirin family
Vc3S01_A1596	COG1278	Cold shock
Vc3S01_A1600	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Vc3S01_A1601	COG3706	GGDEF domain
Vc3S01_A1601	COG0745	RESPONSE REGULATOR receiver
Vc3S01_A1606	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Vc3S01_A1608	COG1686	Belongs to the peptidase S11 family
Vc3S01_A1610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vc3S01_A1611	COG0625	glutathione transferase activity
Vc3S01_A1613	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Vc3S01_A1623	COG1028	Short-chain dehydrogenase reductase Sdr
Vc3S01_A1628	COG3746	phosphate-selective porin O and P
Vc3S01_A1633	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vc3S01_A1642	COG0513	Belongs to the DEAD box helicase family
Vc3S01_A1644	COG0583	DNA-binding transcription factor activity
Vc3S01_A1648	COG1902	pentaerythritol trinitrate reductase activity
Vc3S01_A1650	COG3853	Toxic anion resistance protein (TelA)
Vc3S01_A1652	COG2255	four-way junction helicase activity
Vc3S01_A1655	COG3122	Protein conserved in bacteria
Vc3S01_A1656	COG2321	neutral zinc metallopeptidase
Vc3S01_A1658	COG0583	DNA-binding transcription factor activity
Vc3S01_A1662	COG0252	asparaginase activity
Vc3S01_A1664	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Vc3S01_A1664	COG0574	Belongs to the PEP-utilizing enzyme family
Vc3S01_A1666	COG2197	response regulator
Vc3S01_A1667	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Vc3S01_A1674	COG0583	DNA-binding transcription factor activity
Vc3S01_A1675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vc3S01_A1677	COG1538	Outer membrane efflux protein
Vc3S01_A1679	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Vc3S01_A1680	COG0786	glutamate:sodium symporter activity
Vc3S01_A1684	COG2197	response regulator
Vc3S01_A1686	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vc3S01_A1687	COG0318	PFAM AMP-dependent synthetase and ligase
Vc3S01_A1700	COG4964	Belongs to the GSP D family
Vc3S01_A1713	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vc3S01_A1715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Vc3S01_A1723	COG4948	Mandelate Racemase Muconate Lactonizing
Vc3S01_A1724	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Vc3S01_A1728	COG1342	Belongs to the UPF0251 family
Vc3S01_A1731	COG4176	ABC-type proline glycine betaine transport system permease component
Vc3S01_A1732	COG4175	Glycine betaine
Vc3S01_A1732	COG3448	diguanylate cyclase activity
Vc3S01_A1736	COG0589	response to stress
Vc3S01_A1737	COG0583	DNA-binding transcription factor activity
Vc3S01_A1739	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Vc3S01_A1746	COG1335	isochorismatase
Vc3S01_A1749	COG0753	catalase activity
Vc3S01_A1750	COG0753	catalase activity
Vc3S01_A1754	COG1349	DNA-binding transcription factor activity
Vc3S01_A1755	COG0346	lactoylglutathione lyase activity
Vc3S01_A1756	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vc3S01_A1756	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vc3S01_A1758	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vc3S01_A1759	COG3537	Alpha-1,2-mannosidase
Vc3S01_A1760	COG3537	Alpha-1,2-mannosidase
Vc3S01_A1762	COG3537	Alpha-1,2-mannosidase
Vc3S01_A1763	COG3537	Alpha-1,2-mannosidase
Vc3S01_A1764	COG0737	Belongs to the 5'-nucleotidase family
Vc3S01_A1770	COG1280	lysine exporter protein (LysE YggA)
Vc3S01_A1771	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Vc3S01_A1773	COG0583	DNA-binding transcription factor activity
Vc3S01_A1776	COG4628	conserved protein (DUF2132)
Vc3S01_A1777	COG0488	(ABC) transporter
Vc3S01_A1780	COG0346	lactoylglutathione lyase activity
Vc3S01_A1781	COG0384	phenazine biosynthesis protein PhzF
Vc3S01_A1784	COG3220	belongs to the UPF0276 family
Vc3S01_A1787	COG1271	oxidase subunit
Vc3S01_A1788	COG1294	oxidase, subunit
Vc3S01_A1789	COG0251	oxidation-reduction process
Vc3S01_A1799	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Vc3S01_A1800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Vc3S01_A1804	COG2205	protein histidine kinase activity
Vc3S01_A1805	COG0745	RESPONSE REGULATOR receiver
Vc3S01_A1807	COG0454	-acetyltransferase
Vc3S01_A1809	COG2814	Major facilitator Superfamily
Vc3S01_A1811	COG2988	succinylglutamate desuccinylase activity
Vc3S01_A1819	COG0628	permease
Vc3S01_A1820	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
Vc3S01_A1823	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Vc3S01_A1825	COG4628	conserved protein (DUF2132)
Vc3S01_A1826	COG0583	DNA-binding transcription factor activity
Vc3S01_A1828	COG1686	Belongs to the peptidase S11 family
Vc3S01_A1834	COG0415	Belongs to the DNA photolyase family
Vc3S01_A1835	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Vc3S01_A1837	COG4667	esterase of the alpha-beta hydrolase superfamily
Vc3S01_A1838	COG2095	MarC family integral membrane protein
Vc3S01_A1840	COG2095	MarC family integral membrane protein
Vc3S01_A1844	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Vc3S01_A1851	COG1301	dicarboxylic acid transport
Vc3S01_A1853	COG3339	Conserved Protein
Vc3S01_A1854	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Vc3S01_A1855	COG0700	Nucleoside recognition
Vc3S01_A1856	COG3366	ferrous iron transmembrane transporter activity
Vc3S01_A1859	COG0366	Alpha amylase catalytic
Vc3S01_A1860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Vc3S01_A1861	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Vc3S01_A1862	COG1640	4-alpha-glucanotransferase
Vc3S01_A1863	COG0058	SHG alpha-glucan phosphorylase activity
Vc3S01_A1868	COG1999	signal sequence binding
Vc3S01_A1871	COG1162	GTPase activity
Vc3S01_A1872	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
Vc3S01_A1873	COG0673	inositol 2-dehydrogenase activity
Vc3S01_A1878	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vc3S01_A1879	COG0673	inositol 2-dehydrogenase activity
Vc3S01_A1880	COG3962	Belongs to the TPP enzyme family
Vc3S01_A1882	COG0477	Major facilitator Superfamily
Vc3S01_A1882	COG2814	Major facilitator Superfamily
Vc3S01_A1886	COG0183	Belongs to the thiolase family
Vc3S01_A1887	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Vc3S01_A1892	COG0531	amino acid
Vc3S01_A1893	COG1982	Orn Lys Arg decarboxylase major
Vc3S01_A1897	COG2356	endonuclease I
Vc3S01_A1901	COG4580	involved in the transport of maltose and maltodextrins
Vc3S01_A1904	COG2199	diguanylate cyclase activity
Vc3S01_A1904	COG2203	Gaf domain
Vc3S01_A1909	COG2221	Nitrite and sulphite reductase 4Fe-4S
Vc3S01_A1910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Vc3S01_A1912	COG1760	l-serine dehydratase
Vc3S01_A1917	COG1609	Transcriptional regulator
Vc3S01_A1919	COG2814	Major facilitator Superfamily
Vc3S01_A1925	COG0739	heme binding
Vc3S01_A1928	COG0800	Aldolase
Vc3S01_A1929	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vc3S01_A1930	COG2190	(PTS) system
Vc3S01_A1930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vc3S01_A1930	COG1263	PTS System
Vc3S01_A1932	COG2188	Transcriptional regulator
Vc3S01_A1937	COG3121	Chaperone
Vc3S01_A1938	COG3188	usher protein
Vc3S01_A1943	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vc3S01_A1943	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vc3S01_A1943	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vc3S01_A1945	COG0383	alpha-mannosidase activity
Vc3S01_A1946	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vc3S01_A1951	COG0612	Peptidase, M16
Vc3S01_A1952	COG0840	transmembrane signaling receptor activity
Vc3S01_A1961	COG0463	Glycosyl transferase, family 2
Vc3S01_A1964	COG1335	isochorismatase
Vc3S01_A1965	COG1136	(ABC) transporter
Vc3S01_A1973	COG1764	response to oxidative stress
Vc3S01_A1974	COG1846	Transcriptional regulator
Vc3S01_A1975	COG0450	alkyl hydroperoxide reductase
Vc3S01_A1976	COG3634	alkyl hydroperoxide reductase activity
Vc3S01_A1978	COG2610	gluconate transmembrane transporter activity
Vc3S01_A1979	COG3622	Belongs to the hyi family
Vc3S01_A1980	COG0235	Class ii aldolase
Vc3S01_A1981	COG3395	kinase activity
Vc3S01_A1982	COG2084	Dehydrogenase
Vc3S01_A1983	COG1349	DNA-binding transcription factor activity
Vc3S01_A1986	COG0583	DNA-binding transcription factor activity
Vc3S01_A1987	COG1486	melibiose metabolic process
Vc3S01_A1990	COG1522	sequence-specific DNA binding
Vc3S01_A1991	COG0544	peptidyl-prolyl cis-trans isomerase activity
Vc3S01_A1994	COG2258	MOSC domain
Vc3S01_A1995	COG2153	protein acetylation
Vc3S01_A1997	COG3713	MltA-interacting MipA family protein
Vc3S01_A1998	COG0513	Belongs to the DEAD box helicase family
Vc3S01_A2001	COG0583	DNA-binding transcription factor activity
Vc3S01_A2002	COG1312	Catalyzes the dehydration of D-mannonate
Vc3S01_A2003	COG2186	Transcriptional regulator
Vc3S01_A2005	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Vc3S01_A2007	COG0246	Mannitol dehydrogenase
Vc3S01_A2008	COG1904	glucuronate isomerase
Vc3S01_A2009	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vc3S01_A2010	COG0800	Aldolase
Vc3S01_A2017	COG1132	(ABC) transporter
Vc3S01_A2046	COG4166	transmembrane transport
Vc3S01_A2049	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Vc3S01_A2050	COG1263	PTS System
Vc3S01_A2050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vc3S01_A2051	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vc3S01_A2056	COG1444	tRNA N-acetyltransferase activity
Vc3S01_p10004	COG1192	Involved in chromosome partitioning
Vc3S01_p10010	COG0419	ATPase involved in DNA repair
Vc3S01_p10070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vc3S01_p10077	COG3504	Conjugal transfer protein
Vc3S01_p10080	COG4962	Type ii secretion system protein e
Vc3S01_p10082	COG3451	type IV secretory pathway VirB4
Vc3S01_p10083	COG5268	conjugation
Vc3S01_p20007	COG0517	IMP dehydrogenase activity
Vc3S01_p20008	COG4974	Belongs to the 'phage' integrase family
Vc3S01_p20043	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Vc3S01_p20053	COG1192	Involved in chromosome partitioning
Vc3S01_p20169	COG0551	DNA topoisomerase type I activity
Vc3S01_p20169	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Vc3S01_p20179	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Vc3S01_p20198	COG3941	tape measure
Vc3S01_p20201	COG4397	Mu-like prophage major head subunit gpT
Vc3S01_p30003	COG4943	cyclic-guanylate-specific phosphodiesterase activity
Vc3S01_p30031	COG3015	lipoprotein NlpE involved in copper resistance
Vc3S01_p30049	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
Vc3S01_p30058	COG0732	type I restriction modification DNA specificity domain
Vc3S01_p30059	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Vc3S01_p30067	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Vc3S01_p30086	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Vc3S01_p30092	COG3504	Conjugal transfer protein
Vc3S01_p30093	COG3736	Type IV secretory pathway, component VirB8
Vc3S01_p30098	COG3451	type IV secretory pathway VirB4
Vc3S01_p30107	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
Vc3S01_p30130	COG2261	transglycosylase associated protein
Vc3S01_p40008	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vc3S01_p40018	COG1192	Involved in chromosome partitioning
Vc3S01_p40031	COG2314	TM2 domain
Vc3S01_p40041	COG0484	heat shock protein binding
Vc3S01_p40096	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Vc3S01_p40103	COG2948	multi-organism process
Vc3S01_p40105	COG3736	Type IV secretory pathway, component VirB8
Vc3S01_p40108	COG3451	type IV secretory pathway VirB4
Vc3S01_p40114	COG0629	single-stranded DNA binding
Vc3S01_p40115	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Vc3S01_p40120	COG0330	HflC and HflK could