locus-tag	class	description
C1N50_00010	COG0592	DNA-directed DNA polymerase activity
C1N50_00020	COG0187	DNA topoisomerase II activity
C1N50_00025	COG0071	Belongs to the small heat shock protein (HSP20) family
C1N50_00030	COG3977	Valine--pyruvate aminotransferase
C1N50_00045	COG2119	membrane
C1N50_00055	COG0425	Belongs to the sulfur carrier protein TusA family
C1N50_00070	COG0604	alcohol dehydrogenase
C1N50_00075	COG0183	Belongs to the thiolase family
C1N50_00085	COG1739	Uncharacterized protein family UPF0029
C1N50_00090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1N50_00145	COG2132	Multicopper oxidase
C1N50_00165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C1N50_00170	COG2104	thiamine diphosphate biosynthetic process
C1N50_00185	COG0006	proline dipeptidase activity
C1N50_00185	COG0006	proline dipeptidase activity
C1N50_00195	COG2814	Major facilitator Superfamily
C1N50_00215	COG3220	belongs to the UPF0276 family
C1N50_00225	COG0210	DNA helicase
C1N50_00235	COG0405	Gamma-glutamyltransferase
C1N50_00240	COG1280	lysine exporter protein (LysE YggA)
C1N50_00260	COG2962	Rard protein
C1N50_00265	COG0514	ATP-dependent DNA helicase (RecQ)
C1N50_00280	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C1N50_00295	COG3118	belongs to the thioredoxin family
C1N50_00300	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C1N50_00310	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C1N50_00315	COG0633	Ferredoxin
C1N50_00360	COG3071	HemY protein
C1N50_00365	COG2959	enzyme of heme biosynthesis
C1N50_00370	COG1587	Uroporphyrinogen-III synthase
C1N50_00380	COG3072	Adenylate cyclase
C1N50_00385	COG1965	Belongs to the frataxin family
C1N50_00395	COG0019	diaminopimelate decarboxylase activity
C1N50_00415	COG1011	Hydrolase
C1N50_00420	COG3287	FIST C domain
C1N50_00420	COG2200	EAL domain
C1N50_00420	COG2199	diguanylate cyclase activity
C1N50_00440	COG0561	phosphatase activity
C1N50_00445	COG2267	carboxylic ester hydrolase activity
C1N50_00450	COG1280	lysine exporter protein (LysE YggA)
C1N50_00455	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C1N50_00460	COG0640	Transcriptional regulator
C1N50_00465	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C1N50_00520	COG2095	MarC family integral membrane protein
C1N50_00530	COG0742	ribosomal rna small subunit methyltransferase
C1N50_00535	COG0552	protein localization to endoplasmic reticulum
C1N50_00540	COG2884	Cell division ATP-binding protein ftsE
C1N50_00545	COG2177	Part of the ABC transporter FtsEX involved in
C1N50_00565	COG0705	Rhomboid family
C1N50_00570	COG1580	Controls the rotational direction of flagella during chemotaxis
C1N50_00575	COG3161	chorismate lyase activity
C1N50_00585	COG2937	Belongs to the GPAT DAPAT family
C1N50_00650	COG0534	Mate efflux family protein
C1N50_00760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1N50_00770	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C1N50_00820	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C1N50_00825	COG0250	Participates in transcription elongation, termination and antitermination
C1N50_00840	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C1N50_00865	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
C1N50_00870	COG2816	NAD+ diphosphatase activity
C1N50_00890	COG1573	uracil-dna glycosylase
C1N50_00900	COG3068	Protein conserved in bacteria
C1N50_00905	COG1253	flavin adenine dinucleotide binding
C1N50_00920	COG0151	Belongs to the GarS family
C1N50_00930	COG0789	Transcriptional regulator
C1N50_00935	COG3710	Transcriptional regulator
C1N50_00945	COG0531	amino acid
C1N50_00950	COG1982	Orn Lys Arg decarboxylase major
C1N50_00995	COG3706	GGDEF domain
C1N50_01000	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C1N50_01005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1N50_01020	COG0439	Biotin carboxylase
C1N50_01025	COG0511	ligase activity, forming carbon-carbon bonds
C1N50_01030	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C1N50_01035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1N50_01050	COG2814	Major facilitator Superfamily
C1N50_01055	COG2205	protein histidine kinase activity
C1N50_01055	COG2198	Histidine kinase
C1N50_01055	COG0784	Response regulator, receiver
C1N50_01075	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C1N50_01085	COG2095	MarC family integral membrane protein
C1N50_01095	COG4232	protein-disulfide reductase activity
C1N50_01100	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C1N50_01105	COG1027	Aspartate ammonia-lyase
C1N50_01115	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C1N50_01125	COG2205	protein histidine kinase activity
C1N50_01130	COG0745	RESPONSE REGULATOR receiver
C1N50_01150	COG0534	Mate efflux family protein
C1N50_01155	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C1N50_01175	COG1509	lysine 2,3-aminomutase activity
C1N50_01205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C1N50_01210	COG1053	succinate dehydrogenase
C1N50_01235	COG4942	peptidase
C1N50_01240	COG1045	serine acetyltransferase
C1N50_01250	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C1N50_01255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1N50_01260	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C1N50_01270	COG0840	transmembrane signaling receptor activity
C1N50_01275	COG0471	metal ion transport
C1N50_01285	COG1162	GTPase activity
C1N50_01365	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C1N50_01370	COG0802	atpase or kinase
C1N50_01375	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1N50_01380	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C1N50_01395	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C1N50_01400	COG0330	HflC and HflK could
C1N50_01405	COG0330	HflC and HflK could
C1N50_01410	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C1N50_01415	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C1N50_01425	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C1N50_01430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1N50_01430	COG1017	nitric oxide dioxygenase activity
C1N50_01440	COG0557	exoribonuclease II activity
C1N50_01445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1N50_01450	COG0546	phosphoglycolate phosphatase activity
C1N50_01470	COG0512	Glutamine amidotransferase of anthranilate synthase
C1N50_01475	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C1N50_01495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1N50_01500	COG3954	Phosphoribulokinase
C1N50_01510	COG0429	hydrolase of the alpha beta-hydrolase fold
C1N50_01520	COG0488	(ABC) transporter
C1N50_01530	COG2249	NAD(P)H dehydrogenase (quinone) activity
C1N50_01545	COG1047	Peptidyl-prolyl cis-trans
C1N50_01555	COG1446	asparaginase
C1N50_01570	COG0545	Peptidyl-prolyl cis-trans isomerase
C1N50_01575	COG2964	Protein conserved in bacteria
C1N50_01580	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C1N50_01585	COG2923	Belongs to the DsrF TusC family
C1N50_01590	COG2168	tRNA wobble position uridine thiolation
C1N50_01605	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C1N50_01615	COG2906	2 iron, 2 sulfur cluster binding
C1N50_01625	COG0281	malic enzyme
C1N50_01635	COG0626	cystathionine gamma-synthase activity
C1N50_01640	COG0527	aspartate kinase activity
C1N50_01640	COG0460	homoserine dehydrogenase
C1N50_01645	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C1N50_01655	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C1N50_01665	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C1N50_01680	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C1N50_01680	COG0165	Argininosuccinate lyase
C1N50_01695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1N50_01700	COG0678	peroxiredoxin activity
C1N50_01700	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C1N50_01710	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C1N50_01755	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C1N50_01760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C1N50_01770	COG2965	DNA replication, synthesis of RNA primer
C1N50_01790	COG0305	Participates in initiation and elongation during chromosome replication
C1N50_01795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C1N50_01805	COG0432	Pfam Uncharacterised protein family UPF0047
C1N50_01820	COG0735	belongs to the Fur family
C1N50_01825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1N50_01845	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C1N50_01920	COG1410	methionine synthase
C1N50_01920	COG0646	methionine synthase
C1N50_01925	COG0527	aspartate kinase activity
C1N50_01935	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C1N50_01945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C1N50_01960	COG0629	single-stranded DNA binding
C1N50_01965	COG2200	EAL domain
C1N50_01965	COG2199	diguanylate cyclase activity
C1N50_01990	COG3409	Peptidoglycan-binding domain 1 protein
C1N50_01990	COG3267	Type II secretory pathway component ExeA
C1N50_02000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1N50_02005	COG1459	type II secretion system
C1N50_02015	COG4969	Belongs to the N-Me-Phe pilin family
C1N50_02050	COG1077	Cell shape determining protein MreB Mrl
C1N50_02055	COG1792	Involved in formation and maintenance of cell shape
C1N50_02060	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C1N50_02065	COG0424	maF-like protein
C1N50_02070	COG1530	ribonuclease E activity
C1N50_02075	COG3164	Protein of unknown function
C1N50_02080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1N50_02085	COG0312	modulator of DNA gyrase
C1N50_02090	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C1N50_02105	COG0564	pseudouridine synthase activity
C1N50_02110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C1N50_02120	COG0312	modulator of DNA gyrase
C1N50_02125	COG2239	Acts as a magnesium transporter
C1N50_02130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N50_02140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N50_02145	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C1N50_02155	COG1137	ATPase activity
C1N50_02160	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C1N50_02170	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C1N50_02170	COG0517	IMP dehydrogenase activity
C1N50_02180	COG1127	ABC transporter
C1N50_02185	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C1N50_02190	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C1N50_02195	COG2854	intermembrane phospholipid transfer
C1N50_02205	COG5007	Belongs to the BolA IbaG family
C1N50_02215	COG0204	Acyl-transferase
C1N50_02220	COG0251	oxidation-reduction process
C1N50_02260	COG0456	acetyltransferase
C1N50_02270	COG0525	valine-tRNA ligase activity
C1N50_02275	COG2927	DNA polymerase III (CHI subunit)
C1N50_02285	COG0795	lipopolysaccharide-transporting ATPase activity
C1N50_02290	COG0795	lipopolysaccharide-transporting ATPase activity
C1N50_02300	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_02340	COG0726	polysaccharide deacetylase
C1N50_02345	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C1N50_02355	COG1447	Phosphotransferase system cellobiose-specific component IIA
C1N50_02360	COG1486	melibiose metabolic process
C1N50_02430	COG1012	belongs to the aldehyde dehydrogenase family
C1N50_02530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C1N50_02535	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C1N50_02550	COG0762	integral membrane protein
C1N50_02555	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C1N50_02560	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C1N50_02575	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C1N50_02580	COG1678	Uncharacterized ACR, COG1678
C1N50_02585	COG0189	ligase activity
C1N50_02590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C1N50_02595	COG2356	endonuclease I
C1N50_02615	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C1N50_02635	COG0191	fructose-bisphosphate aldolase activity
C1N50_02640	COG0668	transmembrane transport
C1N50_02655	COG0583	DNA-binding transcription factor activity
C1N50_02660	COG2968	Membrane
C1N50_02665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1N50_02675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C1N50_02685	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C1N50_02700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1N50_02705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1N50_02725	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C1N50_02735	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C1N50_02740	COG1595	DNA-templated transcription, initiation
C1N50_02755	COG3086	response to oxidative stress
C1N50_02765	COG0681	Belongs to the peptidase S26 family
C1N50_02775	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C1N50_02780	COG1381	Involved in DNA repair and RecF pathway recombination
C1N50_02785	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C1N50_02810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C1N50_02815	COG3956	TIGRFAM MazG family protein
C1N50_02825	COG0148	phosphopyruvate hydratase activity
C1N50_02835	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C1N50_02865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C1N50_02875	COG1546	Belongs to the CinA family
C1N50_02880	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C1N50_02895	COG0527	aspartate kinase activity
C1N50_02985	COG5016	pyruvate
C1N50_02985	COG0511	ligase activity, forming carbon-carbon bonds
C1N50_02990	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
C1N50_03000	COG1238	metal cluster binding
C1N50_03005	COG0612	Peptidase, M16
C1N50_03025	COG4536	flavin adenine dinucleotide binding
C1N50_03030	COG4137	Cytochrome C assembly protein
C1N50_03035	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C1N50_03060	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C1N50_03065	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
C1N50_03070	COG0237	dephospho-CoA kinase activity
C1N50_03080	COG1459	type II secretion system
C1N50_03085	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1N50_03110	COG2186	Transcriptional regulator
C1N50_03115	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C1N50_03120	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N50_03125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1N50_03145	COG0288	reversible hydration of carbon dioxide
C1N50_03150	COG0659	secondary active sulfate transmembrane transporter activity
C1N50_03155	COG1131	(ABC) transporter
C1N50_03160	COG0842	Transport permease protein
C1N50_03165	COG1560	Kdo2-lipid A biosynthetic process
C1N50_03180	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C1N50_03195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C1N50_03200	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C1N50_03210	COG1643	Atp-dependent helicase
C1N50_03215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C1N50_03220	COG1752	Esterase of the alpha-beta hydrolase superfamily
C1N50_03225	COG1049	propionate catabolic process, 2-methylcitrate cycle
C1N50_03245	COG0004	ammonium transporteR
C1N50_03250	COG1840	ABC-type Fe3 transport system, periplasmic component
C1N50_03260	COG3842	ATPase activity
C1N50_03265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C1N50_03280	COG2971	BadF BadG BcrA BcrD
C1N50_03290	COG4608	Belongs to the ABC transporter superfamily
C1N50_03295	COG0444	Belongs to the ABC transporter superfamily
C1N50_03300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N50_03310	COG0747	negative chemotaxis
C1N50_03315	COG0784	Response regulator, receiver
C1N50_03315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N50_03315	COG2198	Histidine kinase
C1N50_03315	COG2205	protein histidine kinase activity
C1N50_03330	COG0628	permease
C1N50_03355	COG0739	heme binding
C1N50_03360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C1N50_03370	COG2027	D-alanyl-D-alanine carboxypeptidase
C1N50_03375	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C1N50_03380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1N50_03385	COG1534	Rna-binding protein
C1N50_03395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C1N50_03400	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C1N50_03410	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C1N50_03430	COG0195	Participates in both transcription termination and antitermination
C1N50_03450	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C1N50_03470	COG0534	Mate efflux family protein
C1N50_03495	COG3153	acetyltransferase
C1N50_03520	COG0084	hydrolase, TatD family'
C1N50_03525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1N50_03535	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C1N50_03545	COG0813	purine-nucleoside phosphorylase activity
C1N50_03555	COG0560	Phosphoserine phosphatase
C1N50_03565	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C1N50_03570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C1N50_03600	COG1022	Amp-dependent synthetase and ligase
C1N50_03605	COG0741	lytic transglycosylase activity
C1N50_03610	COG0583	DNA-binding transcription factor activity
C1N50_03630	COG4964	Belongs to the GSP D family
C1N50_03690	COG0583	DNA-binding transcription factor activity
C1N50_03695	COG0531	amino acid
C1N50_03700	COG2731	YhcH YjgK YiaL family protein
C1N50_03705	COG3250	beta-galactosidase activity
C1N50_03710	COG1609	Transcriptional regulator
C1N50_03715	COG0768	penicillin binding
C1N50_03725	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1N50_03730	COG1085	galactose-1-phosphate uridylyltransferase
C1N50_03740	COG2017	converts alpha-aldose to the beta-anomer
C1N50_03750	COG1609	Transcriptional regulator
C1N50_03765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1N50_03785	COG0741	lytic transglycosylase activity
C1N50_03800	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C1N50_03805	COG1349	DNA-binding transcription factor activity
C1N50_03815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C1N50_03825	COG2271	Major facilitator Superfamily
C1N50_03830	COG0584	glycerophosphoryl diester phosphodiesterase
C1N50_03835	COG2171	N-acyltransferase activity
C1N50_03850	COG3141	response to X-ray
C1N50_03870	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C1N50_03875	COG1074	ATP-dependent DNA helicase activity
C1N50_03880	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C1N50_03890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C1N50_03890	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C1N50_03905	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C1N50_03910	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C1N50_03915	COG2166	iron-sulfur cluster assembly
C1N50_03920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C1N50_03925	COG0693	protein deglycase activity
C1N50_03930	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C1N50_03955	COG1595	DNA-templated transcription, initiation
C1N50_03985	COG0271	Belongs to the BolA IbaG family
C1N50_04020	COG1477	protein flavinylation
C1N50_04030	COG3706	GGDEF domain
C1N50_04030	COG0745	RESPONSE REGULATOR receiver
C1N50_04035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C1N50_04040	COG0514	ATP-dependent DNA helicase (RecQ)
C1N50_04045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1N50_04060	COG0733	neurotransmitter:sodium symporter activity
C1N50_04085	COG1720	tRNA m6t6A37 methyltransferase activity
C1N50_04100	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C1N50_04130	COG3098	single-species biofilm formation
C1N50_04135	COG0564	pseudouridine synthase activity
C1N50_04150	COG0024	Methionine aminopeptidase
C1N50_04175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C1N50_04180	COG0575	Belongs to the CDS family
C1N50_04190	COG0750	zinc metalloprotease
C1N50_04200	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C1N50_04205	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C1N50_04230	COG0587	DNA-directed DNA polymerase activity
C1N50_04250	COG0347	Belongs to the P(II) protein family
C1N50_04265	COG0741	lytic transglycosylase activity
C1N50_04265	COG1388	LysM domain
C1N50_04275	COG2226	methyltransferase
C1N50_04285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C1N50_04310	COG1960	acyl-CoA dehydrogenase activity
C1N50_04315	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C1N50_04320	COG0121	glutamine amidotransferase
C1N50_04325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C1N50_04330	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C1N50_04335	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C1N50_04340	COG2233	PERMEase
C1N50_04360	COG4783	chaperone-mediated protein folding
C1N50_04375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C1N50_04380	COG2716	regulation of RNA biosynthetic process
C1N50_04385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C1N50_04410	COG1393	Belongs to the ArsC family
C1N50_04435	COG2837	iron assimilation
C1N50_04440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N50_04450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N50_04455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N50_04460	COG1334	flagellar protein FlaG
C1N50_04465	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C1N50_04475	COG1516	flagellar protein fliS
C1N50_04485	COG4191	Histidine kinase
C1N50_04490	COG2204	response regulator
C1N50_04495	COG1677	Flagellar hook-basal body complex protein FliE
C1N50_04505	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C1N50_04560	COG1987	bacterial-type flagellum assembly
C1N50_04565	COG1684	flagellar biosynthetic protein fliR
C1N50_04585	COG0455	bacterial-type flagellum organization
C1N50_04600	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C1N50_04605	COG0643	Histidine kinase
C1N50_04605	COG2198	Histidine kinase
C1N50_04610	COG2201	protein-glutamate methylesterase activity
C1N50_04615	COG1192	Involved in chromosome partitioning
C1N50_04625	COG0835	chemotaxis
C1N50_04635	COG4133	protoheme IX ABC transporter activity
C1N50_04640	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1N50_04645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1N50_04660	COG1138	Cytochrome C-type biogenesis protein
C1N50_04665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1N50_04675	COG3088	subunit of a heme lyase
C1N50_04675	COG4235	cytochrome complex assembly
C1N50_04680	COG2853	Lipoprotein
C1N50_04685	COG2067	long-chain fatty acid transport protein
C1N50_04710	COG0183	Belongs to the thiolase family
C1N50_04725	COG2062	phosphohistidine phosphatase, SixA
C1N50_04735	COG2890	protein-(glutamine-N5) methyltransferase activity
C1N50_04745	COG2860	membrane
C1N50_04750	COG3101	peptidyl-lysine hydroxylation
C1N50_04775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C1N50_04785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1N50_04790	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C1N50_04815	COG0285	dihydrofolate synthase activity
C1N50_04820	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C1N50_04825	COG1286	toxin biosynthetic process
C1N50_04830	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C1N50_04835	COG0583	DNA-binding transcription factor activity
C1N50_04840	COG0745	RESPONSE REGULATOR receiver
C1N50_04850	COG2832	Protein of unknown function (DUF454)
C1N50_04860	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C1N50_04870	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C1N50_04875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C1N50_04880	COG0814	amino acid
C1N50_04885	COG0251	oxidation-reduction process
C1N50_04895	COG2964	Protein conserved in bacteria
C1N50_04905	COG2983	Belongs to the UPF0260 family
C1N50_04910	COG2261	transglycosylase associated protein
C1N50_04915	COG2985	domain, Protein
C1N50_04920	COG0076	glutamate decarboxylase activity
C1N50_04925	COG0668	transmembrane transport
C1N50_04935	COG0346	lactoylglutathione lyase activity
C1N50_04945	COG1785	Belongs to the alkaline phosphatase family
C1N50_04965	COG2226	methyltransferase
C1N50_04985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C1N50_04990	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N50_05000	COG3139	Protein of unknown function (DUF1315)
C1N50_05005	COG0252	asparaginase activity
C1N50_05010	COG0616	signal peptide processing
C1N50_05015	COG1902	pentaerythritol trinitrate reductase activity
C1N50_05015	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1N50_05020	COG0778	Nitroreductase
C1N50_05025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1N50_05040	COG0123	including yeast histone deacetylase and acetoin utilization protein
C1N50_05050	COG4269	membrane
C1N50_05065	COG3083	sulfuric ester hydrolase activity
C1N50_05090	COG1757	Na H antiporter
C1N50_05095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C1N50_05105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1N50_05110	COG2095	MarC family integral membrane protein
C1N50_05115	COG1012	belongs to the aldehyde dehydrogenase family
C1N50_05115	COG1454	alcohol dehydrogenase
C1N50_05120	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_05135	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C1N50_05150	COG2056	Na+-H+ antiporter family
C1N50_05160	COG2885	chlorophyll binding
C1N50_05170	COG0346	lactoylglutathione lyase activity
C1N50_05175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C1N50_05180	COG4660	Part of a membrane complex involved in electron transport
C1N50_05185	COG4659	FMN binding
C1N50_05190	COG4658	electron transport chain
C1N50_05195	COG4656	Part of a membrane complex involved in electron transport
C1N50_05205	COG4657	Part of a membrane complex involved in electron transport
C1N50_05210	COG1882	Formate acetyltransferase
C1N50_05220	COG0745	RESPONSE REGULATOR receiver
C1N50_05260	COG0556	nucleotide-excision repair
C1N50_05275	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C1N50_05280	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C1N50_05285	COG0521	Mo-molybdopterin cofactor biosynthetic process
C1N50_05295	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C1N50_05300	COG0314	molybdopterin synthase activity
C1N50_05310	COG0601	transmembrane transport
C1N50_05315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N50_05320	COG0444	Belongs to the ABC transporter superfamily
C1N50_05330	COG0435	Glutathione S-transferase
C1N50_05335	COG0280	phosphate acetyltransferase
C1N50_05335	COG0857	belongs to the CobB CobQ family
C1N50_05360	COG4120	Belongs to the binding-protein-dependent transport system permease family
C1N50_05365	COG1122	ATPase activity
C1N50_05370	COG0366	Alpha amylase catalytic
C1N50_05375	COG3706	GGDEF domain
C1N50_05375	COG0745	RESPONSE REGULATOR receiver
C1N50_05380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1N50_05385	COG0653	protein targeting
C1N50_05390	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C1N50_05400	COG2186	Transcriptional regulator
C1N50_05430	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C1N50_05435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1N50_05440	COG0659	secondary active sulfate transmembrane transporter activity
C1N50_05450	COG1530	ribonuclease E activity
C1N50_05455	COG0564	pseudouridine synthase activity
C1N50_05460	COG0424	maF-like protein
C1N50_05465	COG1399	metal-binding, possibly nucleic acid-binding protein
C1N50_05480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1N50_05510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C1N50_05525	COG0084	hydrolase, TatD family'
C1N50_05530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N50_05530	COG1263	PTS System
C1N50_05540	COG0733	neurotransmitter:sodium symporter activity
C1N50_05555	COG4667	esterase of the alpha-beta hydrolase superfamily
C1N50_05585	COG2272	Belongs to the type-B carboxylesterase lipase family
C1N50_05595	COG3710	Transcriptional regulator
C1N50_05610	COG1940	carbohydrate kinase activity
C1N50_05615	COG0784	Response regulator, receiver
C1N50_05615	COG0835	chemotaxis
C1N50_05635	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_05640	COG0616	signal peptide processing
C1N50_05650	COG0539	negative regulation of cytoplasmic translation
C1N50_05660	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C1N50_05665	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C1N50_05675	COG4166	transmembrane transport
C1N50_05690	COG3009	Protein conserved in bacteria
C1N50_05695	COG3008	intermembrane lipid transfer
C1N50_05695	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C1N50_05700	COG2995	paraquat-inducible protein a
C1N50_05705	COG1609	Transcriptional regulator
C1N50_05710	COG3250	beta-galactosidase activity
C1N50_05720	COG4580	involved in the transport of maltose and maltodextrins
C1N50_05730	COG2211	Major facilitator Superfamily
C1N50_05735	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C1N50_05750	COG4232	protein-disulfide reductase activity
C1N50_05755	COG3118	belongs to the thioredoxin family
C1N50_05765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C1N50_05775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N50_05790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N50_05805	COG0577	efflux transmembrane transporter activity
C1N50_05805	COG1136	(ABC) transporter
C1N50_05810	COG0577	efflux transmembrane transporter activity
C1N50_05810	COG1136	(ABC) transporter
C1N50_05825	COG2176	DNA-directed DNA polymerase activity
C1N50_05845	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C1N50_05895	COG3850	Histidine kinase
C1N50_05895	COG5002	protein histidine kinase activity
C1N50_05900	COG0745	RESPONSE REGULATOR receiver
C1N50_05905	COG0463	Glycosyl transferase, family 2
C1N50_05910	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C1N50_05920	COG0840	transmembrane signaling receptor activity
C1N50_05935	COG2175	clavaminate synthase activity
C1N50_05940	COG2964	Protein conserved in bacteria
C1N50_05955	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1N50_05980	COG1032	radical SAM domain protein
C1N50_05985	COG1716	ATPase activity
C1N50_05985	COG5001	Diguanylate cyclase
C1N50_06000	COG0583	DNA-binding transcription factor activity
C1N50_06015	COG2350	Protein conserved in bacteria
C1N50_06020	COG1607	acyl-coa hydrolase
C1N50_06045	COG1301	dicarboxylic acid transport
C1N50_06050	COG0159	tryptophan synthase activity
C1N50_06060	COG0134	indole-3-glycerol-phosphate synthase activity
C1N50_06060	COG0135	phosphoribosylanthranilate isomerase activity
C1N50_06070	COG0512	Glutamine amidotransferase of anthranilate synthase
C1N50_06075	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C1N50_06085	COG0613	PHP domain protein
C1N50_06090	COG0009	L-threonylcarbamoyladenylate synthase
C1N50_06100	COG1187	pseudouridine synthase activity
C1N50_06120	COG0417	DNA replication proofreading
C1N50_06125	COG2197	response regulator
C1N50_06130	COG0322	excinuclease ABC activity
C1N50_06170	COG0019	diaminopimelate decarboxylase activity
C1N50_06185	COG1546	Belongs to the CinA family
C1N50_06185	COG1058	Belongs to the CinA family
C1N50_06195	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1N50_06200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1N50_06225	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C1N50_06235	COG0437	4 iron, 4 sulfur cluster binding
C1N50_06240	COG3301	Polysulphide reductase, NrfD
C1N50_06245	COG1138	Cytochrome C-type biogenesis protein
C1N50_06255	COG4235	cytochrome complex assembly
C1N50_06255	COG3088	subunit of a heme lyase
C1N50_06290	COG2989	Protein conserved in bacteria
C1N50_06295	COG3108	Peptidase M15
C1N50_06300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1N50_06315	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C1N50_06340	COG1846	Transcriptional regulator
C1N50_06345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1N50_06350	COG0840	transmembrane signaling receptor activity
C1N50_06370	COG1448	Aminotransferase
C1N50_06390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N50_06405	COG0017	Asparaginyl-tRNA synthetase
C1N50_06415	COG0720	synthase
C1N50_06420	COG2197	response regulator
C1N50_06435	COG1760	l-serine dehydratase
C1N50_06440	COG0814	amino acid
C1N50_06460	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C1N50_06475	COG3106	COG3106 Predicted ATPase
C1N50_06490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N50_06785	COG2801	Transposase and inactivated derivatives
C1N50_06915	COG2801	Transposase and inactivated derivatives
C1N50_07190	COG2801	Transposase and inactivated derivatives
C1N50_07235	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C1N50_07255	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C1N50_07285	COG2801	Transposase and inactivated derivatives
C1N50_07325	COG4221	oxidoreductase activity
C1N50_07340	COG3340	Belongs to the peptidase S51 family
C1N50_07370	COG0456	acetyltransferase
C1N50_07375	COG0471	metal ion transport
C1N50_07380	COG4191	Histidine kinase
C1N50_07380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N50_07400	COG1280	lysine exporter protein (LysE YggA)
C1N50_07405	COG1328	CTP reductase activity
C1N50_07410	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C1N50_07420	COG0861	Integral membrane protein TerC family
C1N50_07430	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C1N50_07435	COG4221	oxidoreductase activity
C1N50_07440	COG1454	alcohol dehydrogenase
C1N50_07445	COG0814	amino acid
C1N50_07465	COG1132	(ABC) transporter
C1N50_07470	COG1132	(ABC) transporter
C1N50_07480	COG0583	DNA-binding transcription factor activity
C1N50_07505	COG0443	Heat shock 70 kDa protein
C1N50_07510	COG0443	Heat shock 70 kDa protein
C1N50_07520	COG3706	GGDEF domain
C1N50_07550	COG3227	Zinc metalloprotease (Elastase)
C1N50_07570	COG3842	ATPase activity
C1N50_07575	COG3459	Glycosyltransferase 36 associated
C1N50_07585	COG1653	transport
C1N50_07595	COG0395	ABC-type sugar transport system, permease component
C1N50_07610	COG0243	molybdopterin cofactor binding
C1N50_07615	COG0437	4 iron, 4 sulfur cluster binding
C1N50_07620	COG3302	dmso reductase anchor subunit
C1N50_07635	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C1N50_07640	COG1643	Atp-dependent helicase
C1N50_07665	COG3063	Type IV pilus biogenesis stability protein PilW
C1N50_07695	COG0531	amino acid
C1N50_07700	COG1280	lysine exporter protein (LysE YggA)
C1N50_07705	COG1560	Kdo2-lipid A biosynthetic process
C1N50_07725	COG1846	Transcriptional regulator
C1N50_07735	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C1N50_07740	COG1280	lysine exporter protein (LysE YggA)
C1N50_07775	COG1115	amino acid carrier protein
C1N50_07800	COG1368	sulfuric ester hydrolase activity
C1N50_07815	COG0215	cysteine-tRNA ligase activity
C1N50_07820	COG0534	Mate efflux family protein
C1N50_07825	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C1N50_07835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1N50_07840	COG0456	acetyltransferase
C1N50_07845	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C1N50_07850	COG0662	Cupin 2, conserved barrel domain protein
C1N50_07855	COG0527	aspartate kinase activity
C1N50_07865	COG1858	cytochrome C peroxidase
C1N50_07870	COG1404	Belongs to the peptidase S8 family
C1N50_07875	COG3227	Zinc metalloprotease (Elastase)
C1N50_07915	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C1N50_07945	COG0210	DNA helicase
C1N50_07970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N50_07985	COG3290	protein histidine kinase activity
C1N50_07990	COG4565	transcriptional regulatory protein
C1N50_07995	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C1N50_08000	COG0363	glucosamine-6-phosphate deaminase activity
C1N50_08005	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C1N50_08035	COG3284	Transcriptional regulator
C1N50_08040	COG1012	belongs to the aldehyde dehydrogenase family
C1N50_08050	COG0840	transmembrane signaling receptor activity
C1N50_08055	COG0730	response to heat
C1N50_08085	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C1N50_08180	COG3501	Rhs element vgr protein
C1N50_08195	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C1N50_08200	COG0372	Belongs to the citrate synthase family
C1N50_08210	COG2828	Protein conserved in bacteria
C1N50_08245	COG0561	phosphatase activity
C1N50_08250	COG0602	queuosine metabolic process
C1N50_08260	COG3706	GGDEF domain
C1N50_08310	COG0840	transmembrane signaling receptor activity
C1N50_08315	COG1254	Belongs to the acylphosphatase family
C1N50_08320	COG2920	part of a sulfur-relay system
C1N50_08330	COG0670	Belongs to the BI1 family
C1N50_08335	COG1126	abc transporter atp-binding protein
C1N50_08340	COG0765	amino acid transport
C1N50_08345	COG4597	amino acid ABC transporter
C1N50_08350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N50_08370	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1N50_08395	COG3008	intermembrane lipid transfer
C1N50_08400	COG2995	paraquat-inducible protein a
C1N50_08405	COG1132	(ABC) transporter
C1N50_08410	COG1956	GAF domain-containing protein
C1N50_08415	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
C1N50_08430	COG0308	aminopeptidase N
C1N50_08440	COG2902	Dehydrogenase
C1N50_08485	COG1067	ATP-dependent peptidase activity
C1N50_08610	COG3278	Belongs to the heme-copper respiratory oxidase family
C1N50_08625	COG2010	Cytochrome c
C1N50_08635	COG2217	Heavy metal translocating P-type atpase
C1N50_08650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1N50_08655	COG0589	response to stress
C1N50_08680	COG3842	ATPase activity
C1N50_08685	COG1176	ABC-type spermidine putrescine transport system, permease component I
C1N50_08690	COG1177	transmembrane transport
C1N50_08695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C1N50_08700	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C1N50_08705	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C1N50_08720	COG0437	4 iron, 4 sulfur cluster binding
C1N50_08725	COG3383	formate dehydrogenase (NAD+) activity
C1N50_08725	COG0243	molybdopterin cofactor binding
C1N50_08735	COG3381	protein complex oligomerization
C1N50_08755	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C1N50_08760	COG0488	(ABC) transporter
C1N50_08780	COG4191	Histidine kinase
C1N50_08785	COG2204	response regulator
C1N50_08795	COG4662	Binding-protein-dependent transport system inner membrane component
C1N50_08800	COG3842	ATPase activity
C1N50_08810	COG0303	'Molybdopterin
C1N50_08820	COG1940	carbohydrate kinase activity
C1N50_08875	COG3290	protein histidine kinase activity
C1N50_08875	COG0840	transmembrane signaling receptor activity
C1N50_08880	COG0791	NLP P60 protein
C1N50_08890	COG3706	GGDEF domain
C1N50_08895	COG2201	protein-glutamate methylesterase activity
C1N50_08910	COG0307	riboflavin synthase, alpha
C1N50_08915	COG0534	Mate efflux family protein
C1N50_08925	COG1793	dna ligase
C1N50_08935	COG2885	chlorophyll binding
C1N50_08955	COG2204	response regulator
C1N50_08960	COG0438	transferase activity, transferring glycosyl groups
C1N50_08965	COG0438	transferase activity, transferring glycosyl groups
C1N50_08995	COG0438	transferase activity, transferring glycosyl groups
C1N50_09000	COG1215	transferase activity, transferring glycosyl groups
C1N50_09005	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C1N50_09015	COG3064	Membrane
C1N50_09025	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C1N50_09025	COG0116	Belongs to the methyltransferase superfamily
C1N50_09040	COG5001	Diguanylate cyclase
C1N50_09040	COG3300	MHYT domain
C1N50_09045	COG4999	Histidine kinase
C1N50_09045	COG2205	protein histidine kinase activity
C1N50_09045	COG3437	response regulator, receiver
C1N50_09045	COG3850	Histidine kinase
C1N50_09065	COG0110	maltose O-acetyltransferase activity
C1N50_09090	COG1846	Transcriptional regulator
C1N50_09105	COG3247	response to pH
C1N50_09110	COG0668	transmembrane transport
C1N50_09120	COG1404	Belongs to the peptidase S8 family
C1N50_09130	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C1N50_09180	COG0625	glutathione transferase activity
C1N50_09190	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
C1N50_09205	COG2195	Cleaves the N-terminal amino acid of tripeptides
C1N50_09240	COG0813	purine-nucleoside phosphorylase activity
C1N50_09255	COG3706	GGDEF domain
C1N50_09255	COG0745	RESPONSE REGULATOR receiver
C1N50_09265	COG1451	nucleotide metabolic process
C1N50_09295	COG0583	DNA-binding transcription factor activity
C1N50_09325	COG4139	cobalamin transport
C1N50_09340	COG2062	phosphohistidine phosphatase, SixA
C1N50_09350	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
C1N50_09360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C1N50_09370	COG0702	epimerase
C1N50_09385	COG2925	Exonuclease
C1N50_09395	COG1346	cytolysis
C1N50_09445	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N50_09450	COG4605	iron ion homeostasis
C1N50_09455	COG4607	ABC-type enterochelin transport system periplasmic component
C1N50_09460	COG4774	siderophore transport
C1N50_09465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1N50_09470	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C1N50_09480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1N50_09500	COG3433	isochorismatase activity
C1N50_09500	COG1535	isochorismatase
C1N50_09505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1N50_09505	COG0072	phenylalanine-tRNA ligase activity
C1N50_09515	COG3706	GGDEF domain
C1N50_09555	COG0251	oxidation-reduction process
C1N50_09600	COG2188	Transcriptional regulator
C1N50_09610	COG0010	Belongs to the arginase family
C1N50_09620	COG2986	histidine ammonia-lyase
C1N50_09665	COG0247	lactate metabolic process
C1N50_09665	COG0277	FAD linked oxidase domain protein
C1N50_09810	COG1643	Atp-dependent helicase
C1N50_09820	COG2949	membrane
C1N50_09825	COG0471	metal ion transport
C1N50_09830	COG3706	GGDEF domain
C1N50_09850	COG0492	ferredoxin-NADP+ reductase activity
C1N50_09855	COG4988	ABC transporter
C1N50_09860	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C1N50_09870	COG0583	DNA-binding transcription factor activity
C1N50_09875	COG2200	EAL domain
C1N50_09895	COG5001	Diguanylate cyclase
C1N50_09910	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C1N50_09920	COG4191	Histidine kinase
C1N50_09920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N50_09935	COG3070	regulator of competence-specific genes
C1N50_09950	COG2431	L-lysine efflux transmembrane transporter activity
C1N50_09960	COG0076	glutamate decarboxylase activity
C1N50_09965	COG1737	Transcriptional regulator
C1N50_09975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C1N50_09985	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C1N50_10020	COG0534	Mate efflux family protein
C1N50_10025	COG0702	epimerase
C1N50_10030	COG4667	esterase of the alpha-beta hydrolase superfamily
C1N50_10040	COG2814	Major facilitator Superfamily
C1N50_10045	COG1187	pseudouridine synthase activity
C1N50_10050	COG1061	Type III restriction enzyme res subunit
C1N50_10060	COG0745	RESPONSE REGULATOR receiver
C1N50_10065	COG2205	protein histidine kinase activity
C1N50_10115	COG3313	Fe-S protein
C1N50_10125	COG0659	secondary active sulfate transmembrane transporter activity
C1N50_10150	COG0493	'glutamate synthase
C1N50_10160	COG0398	Pfam SNARE associated Golgi protein
C1N50_10165	COG4134	Bacterial extracellular solute-binding protein
C1N50_10170	COG4135	transport system, permease component
C1N50_10175	COG4136	ATPase activity
C1N50_10180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C1N50_10190	COG2814	Major facilitator Superfamily
C1N50_10195	COG3604	Transcriptional regulator
C1N50_10200	COG1151	hydroxylamine reductase activity
C1N50_10205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1N50_10215	COG0564	pseudouridine synthase activity
C1N50_10220	COG0733	neurotransmitter:sodium symporter activity
C1N50_10230	COG0626	cystathionine gamma-synthase activity
C1N50_10235	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C1N50_10255	COG2818	Glycosylase
C1N50_10275	COG1983	PspC domain protein
C1N50_10285	COG1842	Phage shock protein A
C1N50_10290	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C1N50_10300	COG4168	peptide transport system, permease
C1N50_10305	COG4171	peptide transport system, permease
C1N50_10315	COG4172	Belongs to the ABC transporter superfamily
C1N50_10325	COG1227	inorganic diphosphatase activity
C1N50_10340	COG0243	molybdopterin cofactor binding
C1N50_10345	COG3005	denitrification pathway
C1N50_10350	COG4459	periplasmic nitrate reductase
C1N50_10355	COG0390	transport system, permease component
C1N50_10360	COG2116	formate transmembrane transporter activity
C1N50_10385	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C1N50_10390	COG1435	thymidine kinase activity
C1N50_10395	COG0215	cysteine-tRNA ligase activity
C1N50_10400	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C1N50_10405	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C1N50_10410	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C1N50_10415	COG3012	SEC-C Motif Domain Protein
C1N50_10420	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C1N50_10420	COG0140	phosphoribosyl-ATP diphosphatase activity
C1N50_10425	COG0107	imidazoleglycerol-phosphate synthase activity
C1N50_10430	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C1N50_10435	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C1N50_10440	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C1N50_10440	COG0131	Imidazoleglycerol-phosphate dehydratase
C1N50_10450	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C1N50_10460	COG1757	Na H antiporter
C1N50_10470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N50_10490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C1N50_10510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C1N50_10525	COG0300	oxidoreductase activity
C1N50_10550	COG2226	methyltransferase
C1N50_10570	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C1N50_10580	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C1N50_10590	COG1674	ftsk spoiiie
C1N50_10600	COG0686	Belongs to the AlaDH PNT family
C1N50_10610	COG0583	DNA-binding transcription factor activity
C1N50_10635	COG0402	S-adenosylhomocysteine deaminase activity
C1N50_10640	COG4934	collagen metabolic process
C1N50_10645	COG0270	DNA (cytosine-5-)-methyltransferase activity
C1N50_10655	COG3568	Endonuclease Exonuclease Phosphatase
C1N50_10675	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C1N50_10690	COG1288	antiporter activity
C1N50_10700	COG2186	Transcriptional regulator
C1N50_10710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N50_10715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N50_10740	COG0747	negative chemotaxis
C1N50_10745	COG4608	Belongs to the ABC transporter superfamily
C1N50_10750	COG0444	Belongs to the ABC transporter superfamily
C1N50_10755	COG0534	Mate efflux family protein
C1N50_10760	COG2824	Alkylphosphonate utilization operon protein PhnA
C1N50_10780	COG3119	arylsulfatase activity
C1N50_10810	COG0457	Tetratricopeptide repeat
C1N50_10875	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C1N50_10880	COG4790	Type iii secretion
C1N50_10885	COG4794	Type iii secretion
C1N50_10890	COG4791	protein targeting
C1N50_10895	COG4792	protein secretion
C1N50_10910	COG3177	Filamentation induced by cAMP protein fic
C1N50_10940	COG4669	(LipO)protein
C1N50_11070	COG0784	Response regulator, receiver
C1N50_11070	COG2205	protein histidine kinase activity
C1N50_11080	COG0754	glutathionylspermidine amidase activity
C1N50_11090	COG3766	membrane
C1N50_11105	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C1N50_11110	COG2885	chlorophyll binding
C1N50_11115	COG0823	Involved in the tonB-independent uptake of proteins
C1N50_11130	COG0811	peptide transport
C1N50_11135	COG0824	Thioesterase
C1N50_11145	COG4890	Cyd operon protein YbgT
C1N50_11150	COG1294	oxidase, subunit
C1N50_11155	COG1271	oxidase subunit
C1N50_11165	COG0632	four-way junction helicase activity
C1N50_11170	COG0840	transmembrane signaling receptor activity
C1N50_11185	COG1801	Protein of unknown function DUF72
C1N50_11205	COG0189	ligase activity
C1N50_11205	COG4067	protein conserved in archaea
C1N50_11220	COG3568	Endonuclease Exonuclease Phosphatase
C1N50_11225	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C1N50_11230	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C1N50_11240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C1N50_11245	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C1N50_11250	COG0745	RESPONSE REGULATOR receiver
C1N50_11265	COG3070	regulator of competence-specific genes
C1N50_11285	COG0297	glycogen (starch) synthase activity
C1N50_11290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C1N50_11295	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1N50_11325	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C1N50_11330	COG0542	response to heat
C1N50_11340	COG1278	Cold shock
C1N50_11350	COG1187	pseudouridine synthase activity
C1N50_11355	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C1N50_11360	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C1N50_11365	COG1199	ATP-dependent helicase activity
C1N50_11370	COG0730	response to heat
C1N50_11375	COG3923	Primosomal replication protein n
C1N50_11385	COG0708	Exodeoxyribonuclease III
C1N50_11395	COG4215	(ABC) transporter
C1N50_11420	COG1882	Formate acetyltransferase
C1N50_11430	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C1N50_11450	COG2766	serine protein kinase
C1N50_11455	COG2718	Belongs to the UPF0229 family
C1N50_11460	COG2719	SpoVR family
C1N50_11480	COG1132	(ABC) transporter
C1N50_11485	COG0658	competence protein
C1N50_11485	COG2333	competence protein COMEC
C1N50_11495	COG4591	ABC-type transport system involved in lipoprotein release permease component
C1N50_11500	COG1136	(ABC) transporter
C1N50_11505	COG4591	ABC-type transport system involved in lipoprotein release permease component
C1N50_11515	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C1N50_11530	COG1252	NADH dehydrogenase
C1N50_11560	COG0537	adenosine 5'-monophosphoramidase activity
C1N50_11580	COG2217	Heavy metal translocating P-type atpase
C1N50_11590	COG0517	IMP dehydrogenase activity
C1N50_11590	COG0516	GMP reductase activity
C1N50_11595	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
C1N50_11600	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C1N50_11605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1N50_11615	COG3706	GGDEF domain
C1N50_11630	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C1N50_11635	COG1946	Acyl-CoA thioesterase
C1N50_11640	COG1522	sequence-specific DNA binding
C1N50_11660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N50_11715	COG2855	membrane
C1N50_11725	COG0583	DNA-binding transcription factor activity
C1N50_11730	COG2190	(PTS) system
C1N50_11730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N50_11730	COG1263	PTS System
C1N50_11740	COG1441	menaquinone biosynthetic process
C1N50_11745	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C1N50_11750	COG0596	Alpha beta hydrolase
C1N50_11760	COG1169	isochorismate synthase
C1N50_11765	COG0436	Aminotransferase
C1N50_11770	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C1N50_11790	COG1555	photosystem II stabilization
C1N50_11795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1N50_11800	COG0776	regulation of translation
C1N50_11805	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C1N50_11840	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C1N50_11845	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C1N50_11850	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1N50_11870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1N50_11875	COG0569	domain protein
C1N50_11880	COG0513	Belongs to the DEAD box helicase family
C1N50_11885	COG1253	flavin adenine dinucleotide binding
C1N50_11890	COG4771	TonB-dependent receptor
C1N50_11895	COG2977	Belongs to the P-Pant transferase superfamily
C1N50_11905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1N50_11905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1N50_11910	COG3433	isochorismatase activity
C1N50_11910	COG1535	isochorismatase
C1N50_11915	COG1021	2,3-dihydroxybenzoate-AMP ligase
C1N50_11920	COG1169	isochorismate synthase
C1N50_11930	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_11945	COG2226	methyltransferase
C1N50_11960	COG2852	Protein conserved in bacteria
C1N50_11965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1N50_11975	COG2951	lytic endotransglycosylase activity
C1N50_11990	COG2894	cell division
C1N50_11995	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C1N50_12000	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C1N50_12005	COG0318	PFAM AMP-dependent synthetase and ligase
C1N50_12010	COG2267	carboxylic ester hydrolase activity
C1N50_12015	COG3065	identical protein binding
C1N50_12025	COG1214	PFAM Peptidase M22, glycoprotease
C1N50_12030	COG1199	ATP-dependent helicase activity
C1N50_12040	COG0788	formyltetrahydrofolate deformylase activity
C1N50_12055	COG3102	Protein conserved in bacteria
C1N50_12090	COG1918	ferrous iron import across plasma membrane
C1N50_12095	COG4977	sequence-specific DNA binding
C1N50_12100	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C1N50_12105	COG1121	(ABC) transporter
C1N50_12110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1N50_12125	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N50_12130	COG0567	Dehydrogenase, E1 component
C1N50_12140	COG1053	succinate dehydrogenase
C1N50_12145	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C1N50_12150	COG2009	succinate dehydrogenase
C1N50_12160	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C1N50_12175	COG0033	Phosphoglucomutase
C1N50_12185	COG0596	Alpha beta hydrolase
C1N50_12205	COG0735	belongs to the Fur family
C1N50_12210	COG2165	general secretion pathway protein
C1N50_12220	COG2190	(PTS) system
C1N50_12220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N50_12220	COG1263	PTS System
C1N50_12230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C1N50_12235	COG1846	Transcriptional regulator
C1N50_12235	COG1940	carbohydrate kinase activity
C1N50_12240	COG4651	solute:proton antiporter activity
C1N50_12240	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C1N50_12245	COG0367	asparagine synthase
C1N50_12255	COG3104	oligopeptide transport
C1N50_12260	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C1N50_12275	COG3710	Transcriptional regulator
C1N50_12295	COG0622	Phosphoesterase
C1N50_12325	COG1090	epimerase
C1N50_12330	COG0300	oxidoreductase activity
C1N50_12340	COG3118	belongs to the thioredoxin family
C1N50_12345	COG3118	belongs to the thioredoxin family
C1N50_12345	COG0457	Tetratricopeptide repeat
C1N50_12350	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C1N50_12355	COG1215	transferase activity, transferring glycosyl groups
C1N50_12360	COG1215	transferase activity, transferring glycosyl groups
C1N50_12365	COG1192	Involved in chromosome partitioning
C1N50_12380	COG2194	sulfuric ester hydrolase activity
C1N50_12385	COG0330	HflC and HflK could
C1N50_12390	COG1585	Membrane protein implicated in regulation of membrane protease activity
C1N50_12420	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
C1N50_12425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C1N50_12435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N50_12440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1N50_12445	COG2190	(PTS) system
C1N50_12450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N50_12455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N50_12460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N50_12475	COG3951	Flagellar rod assembly protein muramidase FlgJ
C1N50_12475	COG1705	Flagellar rod assembly protein muramidase FlgJ
C1N50_12480	COG1706	bacterial-type flagellum-dependent cell motility
C1N50_12485	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C1N50_12490	COG4786	Flagellar basal body rod
C1N50_12495	COG4787	bacterial-type flagellum-dependent cell motility
C1N50_12500	COG1749	Flagellar hook protein flgE
C1N50_12505	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C1N50_12510	COG1558	bacterial-type flagellum-dependent cell motility
C1N50_12515	COG1815	bacterial-type flagellum-dependent cell motility
C1N50_12520	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C1N50_12525	COG0835	chemotaxis
C1N50_12525	COG0784	Response regulator, receiver
C1N50_12585	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C1N50_12600	COG2608	mercury ion transmembrane transporter activity
C1N50_12600	COG2217	Heavy metal translocating P-type atpase
C1N50_12645	COG2840	Smr protein MutS2
C1N50_12650	COG1187	pseudouridine synthase activity
C1N50_12655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C1N50_12660	COG0737	Belongs to the 5'-nucleotidase family
C1N50_12670	COG2912	Transglutaminase-like superfamily
C1N50_12675	COG3094	Invasion gene expression up-regulator, SirB
C1N50_12680	COG2890	protein-(glutamine-N5) methyltransferase activity
C1N50_12705	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C1N50_12715	COG0012	GTP binding
C1N50_12830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1N50_12845	COG1702	phosphate starvation-inducible protein PhoH
C1N50_12855	COG4535	Mg2 and Co2 transporter CorC
C1N50_12860	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C1N50_12865	COG2888	peptidyl-tyrosine sulfation
C1N50_12875	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
C1N50_12880	COG1466	dna polymerase III delta subunit
C1N50_12885	COG0799	negative regulation of ribosome biogenesis
C1N50_12895	COG0768	penicillin binding
C1N50_12900	COG0772	Belongs to the SEDS family
C1N50_12905	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C1N50_12910	COG1686	Belongs to the peptidase S11 family
C1N50_12930	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C1N50_12935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C1N50_12940	COG0366	Alpha amylase catalytic
C1N50_12945	COG1263	PTS System
C1N50_12945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N50_12955	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C1N50_12960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C1N50_12965	COG2011	ABC-type metal ion transport system permease component
C1N50_12970	COG1464	Belongs to the NlpA lipoprotein family
C1N50_12980	COG0737	Belongs to the 5'-nucleotidase family
C1N50_12985	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
C1N50_13005	COG3706	GGDEF domain
C1N50_13005	COG0745	RESPONSE REGULATOR receiver
C1N50_13010	COG1611	Belongs to the LOG family
C1N50_13030	COG2363	Small membrane protein
C1N50_13040	COG0583	DNA-binding transcription factor activity
C1N50_13055	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C1N50_13065	COG0142	geranyltranstransferase activity
C1N50_13075	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C1N50_13080	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C1N50_13105	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1N50_13105	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1N50_13110	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C1N50_13115	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C1N50_13140	COG2252	PERMEase
C1N50_13145	COG2195	Cleaves the N-terminal amino acid of tripeptides
C1N50_13175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C1N50_13175	COG0047	phosphoribosylformylglycinamidine synthase activity
C1N50_13190	COG0590	tRNA wobble adenosine to inosine editing
C1N50_13195	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C1N50_13235	COG1301	dicarboxylic acid transport
C1N50_13250	COG0497	DNA recombination
C1N50_13260	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1N50_13265	COG2914	Belongs to the UPF0125 (RnfH) family
C1N50_13270	COG2867	negative regulation of translational initiation
C1N50_13315	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C1N50_13335	COG0583	DNA-binding transcription factor activity
C1N50_13340	COG1289	transmembrane transporter activity
C1N50_13360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C1N50_13375	COG0668	transmembrane transport
C1N50_13390	COG0583	DNA-binding transcription factor activity
C1N50_13400	COG1115	amino acid carrier protein
C1N50_13405	COG1584	GPR1 FUN34 yaaH family protein
C1N50_13415	COG1757	Na H antiporter
C1N50_13425	COG0517	IMP dehydrogenase activity
C1N50_13425	COG0516	GMP reductase activity
C1N50_13440	COG2199	diguanylate cyclase activity
C1N50_13440	COG2203	Gaf domain
C1N50_13455	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1N50_13460	COG2976	Protein conserved in bacteria
C1N50_13495	COG2975	iron-sulfur cluster assembly
C1N50_13500	COG0633	Ferredoxin
C1N50_13515	COG0316	Belongs to the HesB IscA family
C1N50_13520	COG0822	iron-sulfur transferase activity
C1N50_13535	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C1N50_13540	COG0483	inositol monophosphate 1-phosphatase activity
C1N50_13545	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N50_13550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N50_13555	COG1862	Preprotein translocase
C1N50_13580	COG0517	IMP dehydrogenase activity
C1N50_13590	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C1N50_13595	COG0583	DNA-binding transcription factor activity
C1N50_13600	COG0450	alkyl hydroperoxide reductase
C1N50_13630	COG0704	Plays a role in the regulation of phosphate uptake
C1N50_13635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C1N50_13640	COG0581	inorganic phosphate transmembrane transporter activity
C1N50_13645	COG0573	inorganic phosphate transmembrane transporter activity
C1N50_13650	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C1N50_13655	COG0248	Ppx GppA phosphatase
C1N50_13665	COG5002	protein histidine kinase activity
C1N50_13670	COG0745	RESPONSE REGULATOR receiver
C1N50_13685	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1N50_13750	COG0542	response to heat
C1N50_13760	COG0564	pseudouridine synthase activity
C1N50_13765	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1N50_13770	COG0741	lytic transglycosylase activity
C1N50_13775	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C1N50_13780	COG0077	Prephenate dehydratase
C1N50_13780	COG1605	Chorismate mutase
C1N50_13785	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
C1N50_13800	COG0488	(ABC) transporter
C1N50_13810	COG0739	heme binding
C1N50_13815	COG1605	Chorismate mutase
C1N50_13815	COG0287	Prephenate dehydrogenase
C1N50_13820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1N50_13825	COG1472	Belongs to the glycosyl hydrolase 3 family
C1N50_13830	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C1N50_13850	COG1966	Carbon starvation protein
C1N50_13855	COG3275	phosphorelay sensor kinase activity
C1N50_13860	COG3279	Response regulator of the LytR AlgR family
C1N50_13865	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C1N50_13870	COG1047	Peptidyl-prolyl cis-trans
C1N50_13885	COG0196	riboflavin kinase activity
C1N50_13890	COG0728	peptidoglycan biosynthetic process
C1N50_13895	COG0268	Binds directly to 16S ribosomal RNA
C1N50_13900	COG0640	Transcriptional regulator
C1N50_13905	COG0583	DNA-binding transcription factor activity
C1N50_13910	COG1283	sodium-dependent phosphate transmembrane transporter activity
C1N50_13925	COG0730	response to heat
C1N50_13955	COG0667	Aldo Keto reductase
C1N50_13980	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C1N50_13985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1N50_13995	COG0716	FMN binding
C1N50_14010	COG0513	Belongs to the DEAD box helicase family
C1N50_14020	COG3022	response to hydroperoxide
C1N50_14025	COG1115	amino acid carrier protein
C1N50_14060	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C1N50_14065	COG0083	homoserine kinase activity
C1N50_14080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C1N50_14095	COG0745	RESPONSE REGULATOR receiver
C1N50_14105	COG2198	Histidine kinase
C1N50_14105	COG0784	Response regulator, receiver
C1N50_14105	COG5002	protein histidine kinase activity
C1N50_14115	COG3706	GGDEF domain
C1N50_14115	COG2203	Gaf domain
C1N50_14115	COG5001	Diguanylate cyclase
C1N50_14115	COG4251	negative regulation of phosphorylation
C1N50_14120	COG1242	4 iron, 4 sulfur cluster binding
C1N50_14125	COG0069	glutamate synthase activity
C1N50_14125	COG0067	glutamate synthase
C1N50_14125	COG0070	glutamate synthase
C1N50_14135	COG0067	glutamate synthase
C1N50_14135	COG0069	glutamate synthase activity
C1N50_14135	COG0070	glutamate synthase
C1N50_14140	COG0493	'glutamate synthase
C1N50_14165	COG2860	membrane
C1N50_14170	COG0583	DNA-binding transcription factor activity
C1N50_14175	COG0730	response to heat
C1N50_14190	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C1N50_14195	COG0505	Belongs to the CarA family
C1N50_14205	COG0494	nUDIX hydrolase
C1N50_14225	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C1N50_14230	COG0849	cell division
C1N50_14235	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C1N50_14250	COG0772	Belongs to the SEDS family
C1N50_14265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C1N50_14270	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C1N50_14275	COG0768	penicillin binding
C1N50_14280	COG3116	cell division
C1N50_14305	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C1N50_14320	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C1N50_14325	COG2823	Periplasmic or secreted lipoprotein
C1N50_14330	COG2969	positive regulation of protein catabolic process
C1N50_14335	COG0625	glutathione transferase activity
C1N50_14340	COG2857	Cytochrome c1
C1N50_14345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C1N50_14350	COG0723	plastoquinol--plastocyanin reductase activity
C1N50_14370	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C1N50_14380	COG3105	Protein conserved in bacteria
C1N50_14385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1N50_14390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1N50_14395	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C1N50_14400	COG0187	DNA topoisomerase II activity
C1N50_14405	COG3150	esterase
C1N50_14415	COG3151	Protein conserved in bacteria
C1N50_14420	COG0494	nUDIX hydrolase
C1N50_14425	COG1538	Outer membrane efflux protein
C1N50_14435	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C1N50_14445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C1N50_14450	COG3025	triphosphatase activity
C1N50_14455	COG1392	Phosphate transport regulator
C1N50_14460	COG0306	phosphate transporter
C1N50_14465	COG4991	sh3 domain protein
C1N50_14475	COG3409	Peptidoglycan-binding domain 1 protein
C1N50_14475	COG3267	Type II secretory pathway component ExeA
C1N50_14490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C1N50_14495	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C1N50_14505	COG0596	Alpha beta hydrolase
C1N50_14510	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C1N50_14515	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C1N50_14520	COG1610	YqeY-like protein
C1N50_14525	COG0358	DNA primase activity
C1N50_14530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C1N50_14540	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C1N50_14590	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N50_14590	COG2213	PTS system mannitol-specific
C1N50_14600	COG3722	fumarate hydratase activity
C1N50_14605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1N50_14615	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C1N50_14620	COG1349	DNA-binding transcription factor activity
C1N50_14625	COG0469	pyruvate kinase activity
C1N50_14635	COG3706	GGDEF domain
C1N50_14640	COG0440	acetolactate synthase activity
C1N50_14645	COG0028	Belongs to the TPP enzyme family
C1N50_14650	COG1022	Amp-dependent synthetase and ligase
C1N50_14655	COG0583	DNA-binding transcription factor activity
C1N50_14685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C1N50_14690	COG0473	3-isopropylmalate dehydrogenase activity
C1N50_14710	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C1N50_14715	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C1N50_14720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1N50_14725	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C1N50_14750	COG3610	response to peptide
C1N50_14755	COG2966	Psort location CytoplasmicMembrane, score
C1N50_14770	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C1N50_14775	COG0142	geranyltranstransferase activity
C1N50_14810	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
C1N50_14815	COG1178	ABC-type Fe3 transport system permease component
C1N50_14820	COG4143	(ABC) transporter
C1N50_14825	COG0163	prenyltransferase activity
C1N50_14830	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C1N50_14840	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C1N50_14855	COG2105	PFAM AIG2 family protein
C1N50_14865	COG0729	surface antigen
C1N50_14870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N50_14880	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C1N50_14895	COG1136	(ABC) transporter
C1N50_14915	COG0529	Catalyzes the synthesis of activated sulfate
C1N50_14920	COG0471	metal ion transport
C1N50_14920	COG3273	potassium ion transport
C1N50_14935	COG1648	precorrin-2 dehydrogenase activity
C1N50_14935	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C1N50_14940	COG0737	Belongs to the 5'-nucleotidase family
C1N50_14950	COG0513	Belongs to the DEAD box helicase family
C1N50_14955	COG2153	protein acetylation
C1N50_14970	COG0545	Peptidyl-prolyl cis-trans isomerase
C1N50_14980	COG0203	ribosomal protein L17
C1N50_14985	COG0202	RNA polymerase activity
C1N50_14995	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C1N50_15000	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C1N50_15010	COG0201	protein transport
C1N50_15020	COG1841	ribosomal large subunit assembly
C1N50_15105	COG0088	Forms part of the polypeptide exit tunnel
C1N50_15125	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C1N50_15130	COG1609	Transcriptional regulator
C1N50_15155	COG1575	Belongs to the MenA family. Type 1 subfamily
C1N50_15160	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C1N50_15175	COG1494	fructose-1,6-bisphosphatase
C1N50_15205	COG0149	triose-phosphate isomerase activity
C1N50_15230	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C1N50_15240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C1N50_15245	COG0438	transferase activity, transferring glycosyl groups
C1N50_15250	COG0438	transferase activity, transferring glycosyl groups
C1N50_15275	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C1N50_15280	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C1N50_15285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C1N50_15290	COG1216	Glycosyl transferase, family 2
C1N50_15290	COG0463	Glycosyl transferase, family 2
C1N50_15325	COG1083	cytidylyl-transferase
C1N50_15330	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C1N50_15340	COG2089	acid synthase
C1N50_15345	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C1N50_15350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C1N50_15390	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1N50_15400	COG1560	Kdo2-lipid A biosynthetic process
C1N50_15405	COG0859	PFAM glycosyl transferase family 9
C1N50_15410	COG1519	Transferase
C1N50_15425	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_15470	COG3642	lipopolysaccharide core region biosynthetic process
C1N50_15475	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C1N50_15480	COG0438	transferase activity, transferring glycosyl groups
C1N50_15485	COG0859	PFAM glycosyl transferase family 9
C1N50_15545	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C1N50_15555	COG1560	Kdo2-lipid A biosynthetic process
C1N50_15565	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C1N50_15570	COG1561	YicC-like family, N-terminal region
C1N50_15590	COG4608	Belongs to the ABC transporter superfamily
C1N50_15595	COG0444	Belongs to the ABC transporter superfamily
C1N50_15600	COG0747	negative chemotaxis
C1N50_15605	COG4239	(ABC) transporter, permease
C1N50_15610	COG4174	ABC transporter (Permease)
C1N50_15615	COG4206	TonB-dependent receptor
C1N50_15630	COG0811	peptide transport
C1N50_15635	COG0848	biopolymer transport protein
C1N50_15655	COG0194	GDP metabolic process
C1N50_15660	COG1758	RNA polymerase activity
C1N50_15665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C1N50_15670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1N50_15675	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C1N50_15685	COG2233	PERMEase
C1N50_15690	COG2205	protein histidine kinase activity
C1N50_15695	COG0745	RESPONSE REGULATOR receiver
C1N50_15700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1N50_15710	COG2183	response to ionizing radiation
C1N50_15725	COG1040	competence protein
C1N50_15735	COG0494	nUDIX hydrolase
C1N50_15740	COG1218	3'(2'),5'-bisphosphate nucleotidase
C1N50_15750	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C1N50_15755	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C1N50_15760	COG3156	type II secretion system protein K
C1N50_15765	COG4795	General secretion pathway protein
C1N50_15770	COG2165	general secretion pathway protein
C1N50_15775	COG2165	general secretion pathway protein
C1N50_15780	COG2165	general secretion pathway protein
C1N50_15785	COG1459	type II secretion system
C1N50_15790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1N50_15800	COG3031	protein transport across the cell outer membrane
C1N50_15805	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C1N50_15825	COG0456	acetyltransferase
C1N50_15830	COG1490	D-aminoacyl-tRNA deacylase activity
C1N50_15860	COG0174	glutamine synthetase
C1N50_15870	COG3852	Histidine kinase
C1N50_15875	COG2204	response regulator
C1N50_15880	COG3300	MHYT domain
C1N50_15880	COG5001	Diguanylate cyclase
C1N50_15885	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C1N50_15890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C1N50_15920	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C1N50_15930	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1N50_15930	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1N50_15950	COG0084	hydrolase, TatD family'
C1N50_15955	COG0805	protein transport
C1N50_15975	COG3165	ubiquinone biosynthetic process from chorismate
C1N50_15985	COG1322	Protein conserved in bacteria
C1N50_16000	COG1910	domain protein
C1N50_16020	COG2081	HI0933 family
C1N50_16030	COG1528	Iron-storage protein
C1N50_16035	COG0589	response to stress
C1N50_16040	COG0697	spore germination
C1N50_16055	COG5002	protein histidine kinase activity
C1N50_16055	COG5001	Diguanylate cyclase
C1N50_16060	COG1522	sequence-specific DNA binding
C1N50_16075	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C1N50_16085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1N50_16090	COG0800	Aldolase
C1N50_16095	COG2610	gluconate transmembrane transporter activity
C1N50_16100	COG3265	gluconokinase activity
C1N50_16105	COG0129	dihydroxy-acid dehydratase activity
C1N50_16115	COG2076	Multidrug Resistance protein
C1N50_16120	COG0583	DNA-binding transcription factor activity
C1N50_16125	COG1609	Transcriptional regulator
C1N50_16130	COG0515	serine threonine protein kinase
C1N50_16160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N50_16170	COG4166	transmembrane transport
C1N50_16175	COG4172	Belongs to the ABC transporter superfamily
C1N50_16225	COG1309	transcriptional regulator
C1N50_16230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N50_16235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N50_16245	COG2960	long-chain fatty acid transporting porin activity
C1N50_16250	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C1N50_16255	COG0583	DNA-binding transcription factor activity
C1N50_16310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C1N50_16335	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C1N50_16340	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C1N50_16345	COG0551	DNA topoisomerase type I activity
C1N50_16355	COG0758	DNA mediated transformation
C1N50_16365	COG0242	peptide deformylase activity
C1N50_16375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C1N50_16375	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C1N50_16380	COG0569	domain protein
C1N50_16385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1N50_16395	COG1272	protein, Hemolysin III
C1N50_16400	COG4326	sporulation control protein
C1N50_16410	COG3084	Protein conserved in bacteria
C1N50_16420	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C1N50_16425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1N50_16430	COG0204	Acyl-transferase
C1N50_16440	COG2199	diguanylate cyclase activity
C1N50_16445	COG0606	chelatase, subunit chli
C1N50_16455	COG3978	acetolactate synthase activity
C1N50_16460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C1N50_16465	COG0129	dihydroxy-acid dehydratase activity
C1N50_16475	COG0583	DNA-binding transcription factor activity
C1N50_16480	COG2814	Major facilitator Superfamily
C1N50_16485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N50_16490	COG0765	amino acid transport
C1N50_16500	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C1N50_16510	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C1N50_16540	COG3312	ion transport
C1N50_16545	COG1475	DNA binding
C1N50_16550	COG1192	Involved in chromosome partitioning
C1N50_16565	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C1N50_16580	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C1N50_16595	COG1126	abc transporter atp-binding protein
C1N50_16620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C1N50_16630	COG0584	glycerophosphoryl diester phosphodiesterase
C1N50_16635	COG0745	RESPONSE REGULATOR receiver
C1N50_16655	COG0811	peptide transport
C1N50_16660	COG0811	peptide transport
C1N50_16665	COG0848	biopolymer transport protein
C1N50_16710	COG0803	Belongs to the bacterial solute-binding protein 9 family
C1N50_16715	COG1121	(ABC) transporter
C1N50_16720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1N50_16735	COG1770	oligopeptidase
C1N50_16740	COG2814	Major facilitator Superfamily
C1N50_16745	COG0010	Belongs to the arginase family
C1N50_16750	COG1166	arginine decarboxylase activity
C1N50_16760	COG4067	protein conserved in archaea
C1N50_16760	COG0189	ligase activity
C1N50_16765	COG0189	ligase activity
C1N50_16775	COG0583	DNA-binding transcription factor activity
C1N50_16815	COG1114	Component of the transport system for branched-chain amino acids
C1N50_16835	COG0579	oxidoreductase
C1N50_16855	COG3033	Beta-eliminating lyase
C1N50_16875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1N50_16880	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C1N50_16915	COG3706	GGDEF domain
C1N50_16920	COG0415	Belongs to the DNA photolyase family
C1N50_16925	COG3046	protein related to deoxyribodipyrimidine photolyase
C1N50_16940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N50_16940	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N50_16945	COG1765	OsmC-like protein
C1N50_16980	COG1011	Hydrolase
C1N50_17005	COG3240	lipase activity
C1N50_17035	COG1840	ABC-type Fe3 transport system, periplasmic component
C1N50_17045	COG3842	ATPase activity
C1N50_17070	COG2990	Protein conserved in bacteria
C1N50_17080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1N50_17085	COG2866	Carboxypeptidase
C1N50_17095	COG0583	DNA-binding transcription factor activity
C1N50_17125	COG1760	l-serine dehydratase
C1N50_17150	COG1388	LysM domain
C1N50_17150	COG0741	lytic transglycosylase activity
C1N50_17170	COG1815	bacterial-type flagellum-dependent cell motility
C1N50_17175	COG1558	bacterial-type flagellum-dependent cell motility
C1N50_17180	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C1N50_17185	COG1749	Flagellar hook protein flgE
C1N50_17190	COG4787	bacterial-type flagellum-dependent cell motility
C1N50_17195	COG4786	Flagellar basal body rod
C1N50_17200	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C1N50_17205	COG1706	bacterial-type flagellum-dependent cell motility
C1N50_17215	COG1256	bacterial-type flagellum assembly
C1N50_17215	COG4786	Flagellar basal body rod
C1N50_17220	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N50_17285	COG0384	phenazine biosynthesis protein PhzF
C1N50_17295	COG1360	Flagellar Motor Protein
C1N50_17300	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C1N50_17305	COG1191	sigma factor activity
C1N50_17310	COG1580	Controls the rotational direction of flagella during chemotaxis
C1N50_17325	COG1516	flagellar protein fliS
C1N50_17330	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C1N50_17340	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N50_17355	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C1N50_17365	COG1987	bacterial-type flagellum assembly
C1N50_17390	COG2204	response regulator
C1N50_17405	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C1N50_17425	COG2200	EAL domain
C1N50_17470	COG0346	lactoylglutathione lyase activity
C1N50_17495	COG0745	RESPONSE REGULATOR receiver
C1N50_17520	COG0156	8-amino-7-oxononanoate synthase activity
C1N50_17525	COG1063	alcohol dehydrogenase
C1N50_17550	COG2203	Gaf domain
C1N50_17550	COG2199	diguanylate cyclase activity
C1N50_17555	COG2223	nitrite transmembrane transporter activity
C1N50_17560	COG1063	alcohol dehydrogenase
C1N50_17570	COG0668	transmembrane transport
C1N50_17580	COG1304	FMN binding
C1N50_17585	COG1620	l-lactate permease
C1N50_17590	COG0583	DNA-binding transcription factor activity
C1N50_17595	COG1505	serine-type exopeptidase activity
C1N50_17600	COG4172	Belongs to the ABC transporter superfamily
C1N50_17610	COG1067	ATP-dependent peptidase activity
C1N50_17620	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C1N50_17640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N50_17660	COG1122	ATPase activity
C1N50_17670	COG1566	PFAM secretion protein HlyD family protein
C1N50_17685	COG3706	GGDEF domain
C1N50_17700	COG0813	purine-nucleoside phosphorylase activity
C1N50_17710	COG3272	Protein of unknown function (DUF1722)
C1N50_17715	COG0789	Transcriptional regulator
C1N50_17720	COG0415	Belongs to the DNA photolyase family
C1N50_17725	COG1376	ErfK ybiS ycfS ynhG family protein
C1N50_17725	COG1388	LysM domain
C1N50_17735	COG0513	Belongs to the DEAD box helicase family
C1N50_17740	COG1770	oligopeptidase
C1N50_17745	COG4771	TonB-dependent receptor
C1N50_17765	COG0840	transmembrane signaling receptor activity
C1N50_17770	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C1N50_17775	COG0573	inorganic phosphate transmembrane transporter activity
C1N50_17780	COG0581	inorganic phosphate transmembrane transporter activity
C1N50_17785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C1N50_17820	COG0714	Associated with various cellular activities
C1N50_17840	COG2197	response regulator
C1N50_17865	COG0110	maltose O-acetyltransferase activity
C1N50_17875	COG4191	Histidine kinase
C1N50_17880	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_17915	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C1N50_17920	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
C1N50_17930	COG1252	NADH dehydrogenase
C1N50_17935	COG1301	dicarboxylic acid transport
C1N50_17940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1N50_17970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N50_17970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N50_17970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N50_17975	COG2207	Transcriptional regulator
C1N50_17985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N50_17990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N50_18000	COG2084	Dehydrogenase
C1N50_18005	COG0753	catalase activity
C1N50_18015	COG2130	NADP-dependent
C1N50_18020	COG1309	transcriptional regulator
C1N50_18065	COG3206	protein involved in exopolysaccharide biosynthesis
C1N50_18065	COG0489	protein tyrosine kinase activity
C1N50_18080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C1N50_18085	COG2200	EAL domain
C1N50_18120	COG3842	ATPase activity
C1N50_18135	COG1175	transmembrane transport
C1N50_18170	COG2354	Protein conserved in bacteria
C1N50_18185	COG0401	homolog of Blt101
C1N50_18190	COG3217	Mosc domain protein beta barrel domain protein
C1N50_18190	COG0633	Ferredoxin
C1N50_18190	COG3217	Mosc domain protein beta barrel domain protein
C1N50_18190	COG0633	Ferredoxin
C1N50_18200	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C1N50_18240	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
C1N50_18245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N50_18255	COG0848	biopolymer transport protein
C1N50_18260	COG0811	peptide transport
C1N50_18265	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C1N50_18275	COG3721	Heme iron utilization protein
C1N50_18280	COG0748	coenzyme F420 binding
C1N50_18295	COG0835	chemotaxis
C1N50_18295	COG0784	Response regulator, receiver
C1N50_18300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1N50_18305	COG0366	Alpha amylase catalytic
C1N50_18340	COG0583	DNA-binding transcription factor activity
C1N50_18355	COG2249	NAD(P)H dehydrogenase (quinone) activity
C1N50_18360	COG0583	DNA-binding transcription factor activity
C1N50_18380	COG2814	Major facilitator Superfamily
C1N50_18390	COG4977	sequence-specific DNA binding
C1N50_18400	COG2194	sulfuric ester hydrolase activity
C1N50_18405	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C1N50_18415	COG2205	protein histidine kinase activity
C1N50_18420	COG0745	RESPONSE REGULATOR receiver
C1N50_18425	COG4221	oxidoreductase activity
C1N50_18440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1N50_18460	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C1N50_18470	COG2814	Major facilitator Superfamily
C1N50_18485	COG1418	mRNA catabolic process
C1N50_18500	COG0402	S-adenosylhomocysteine deaminase activity
C1N50_18505	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C1N50_18510	COG2239	Acts as a magnesium transporter
C1N50_18515	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C1N50_18520	COG1566	PFAM secretion protein HlyD family protein
C1N50_18545	COG0745	RESPONSE REGULATOR receiver
C1N50_18550	COG2205	protein histidine kinase activity
C1N50_18560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N50_18565	COG0531	amino acid
C1N50_18580	COG0583	DNA-binding transcription factor activity
C1N50_18600	COG5002	protein histidine kinase activity
C1N50_18600	COG2205	protein histidine kinase activity
C1N50_18600	COG0784	Response regulator, receiver
C1N50_18605	COG0673	inositol 2-dehydrogenase activity
C1N50_18685	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N50_18690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N50_18700	COG1280	lysine exporter protein (LysE YggA)
C1N50_18710	COG0183	Belongs to the thiolase family
C1N50_18735	COG3005	denitrification pathway
C1N50_18755	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1N50_18760	COG3850	Histidine kinase
C1N50_18765	COG2197	response regulator
C1N50_18780	COG2195	Cleaves the N-terminal amino acid of tripeptides
C1N50_18805	COG0840	transmembrane signaling receptor activity
C1N50_18815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1N50_18820	COG0545	Peptidyl-prolyl cis-trans isomerase
C1N50_18850	COG1278	Cold shock
C1N50_18855	COG3036	rescue of stalled ribosome
C1N50_18865	COG2199	diguanylate cyclase activity
C1N50_18885	COG0577	efflux transmembrane transporter activity
C1N50_18885	COG1136	(ABC) transporter
C1N50_18895	COG0840	transmembrane signaling receptor activity
C1N50_18900	COG0783	Belongs to the Dps family
C1N50_18910	COG1619	proteins homologs of microcin C7 resistance protein MccF
C1N50_18915	COG2133	pyrroloquinoline quinone binding
C1N50_18920	COG1454	alcohol dehydrogenase
C1N50_18925	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C1N50_18945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C1N50_18955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1N50_18960	COG3186	Phenylalanine-4-hydroxylase
C1N50_18995	COG3530	Putative quorum-sensing-regulated virulence factor
C1N50_19005	COG0454	-acetyltransferase
C1N50_19035	COG0523	cobalamin synthesis protein
C1N50_19045	COG0513	Belongs to the DEAD box helicase family
C1N50_19065	COG2200	EAL domain
C1N50_19070	COG1119	ATPase activity
C1N50_19100	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C1N50_19115	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
C1N50_19120	COG0513	Belongs to the DEAD box helicase family
C1N50_19125	COG5001	Diguanylate cyclase
C1N50_19135	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C1N50_19150	COG3278	Belongs to the heme-copper respiratory oxidase family
C1N50_19195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C1N50_19200	COG1960	acyl-CoA dehydrogenase activity
C1N50_19210	COG0183	Belongs to the thiolase family
C1N50_19225	COG1024	Enoyl-CoA hydratase
C1N50_19230	COG1024	Enoyl-CoA hydratase
C1N50_19240	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_19245	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C1N50_19250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C1N50_19255	COG1845	cytochrome c oxidase, subunit III
C1N50_19260	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C1N50_19270	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1N50_19270	COG1902	pentaerythritol trinitrate reductase activity
C1N50_19285	COG1012	belongs to the aldehyde dehydrogenase family
C1N50_19295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1N50_19345	COG1126	abc transporter atp-binding protein
C1N50_19350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N50_19355	COG4215	(ABC) transporter
C1N50_19360	COG4160	amino acid transport
C1N50_19385	COG2200	EAL domain
C1N50_19435	COG0443	Heat shock 70 kDa protein
C1N50_19470	COG0745	RESPONSE REGULATOR receiver
C1N50_19485	COG1785	Belongs to the alkaline phosphatase family
C1N50_19505	COG3706	GGDEF domain
C1N50_19515	COG0814	amino acid
C1N50_19520	COG0456	acetyltransferase
C1N50_19525	COG0243	molybdopterin cofactor binding
C1N50_19530	COG1648	precorrin-2 dehydrogenase activity
C1N50_19530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C1N50_19555	COG1116	anion transmembrane transporter activity
C1N50_19555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C1N50_19560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1N50_19565	COG1116	anion transmembrane transporter activity
C1N50_19570	COG2146	nitrite reductase [NAD(P)H] activity
C1N50_19570	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C1N50_19610	COG1902	pentaerythritol trinitrate reductase activity
C1N50_19620	COG0739	heme binding
C1N50_19630	COG3038	cytochrome b561
C1N50_19645	COG3706	GGDEF domain
C1N50_19645	COG0745	RESPONSE REGULATOR receiver
C1N50_19725	COG2814	Major facilitator Superfamily
C1N50_19730	COG1280	lysine exporter protein (LysE YggA)
C1N50_19770	COG1132	(ABC) transporter
C1N50_19780	COG5640	endopeptidase activity
C1N50_19795	COG0583	DNA-binding transcription factor activity
C1N50_19830	COG1120	ATPase activity
C1N50_19835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N50_19840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N50_19845	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C1N50_19940	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_19945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N50_19950	COG1720	tRNA m6t6A37 methyltransferase activity
C1N50_19980	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C1N50_19990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C1N50_20000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N50_20005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N50_20020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N50_20020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N50_20020	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C1N50_20025	COG1105	Belongs to the carbohydrate kinase PfkB family
C1N50_20030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N50_20030	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N50_20035	COG1609	Transcriptional regulator
C1N50_20050	COG2203	Gaf domain
C1N50_20050	COG2199	diguanylate cyclase activity
C1N50_20050	COG2200	EAL domain
C1N50_20055	COG0765	amino acid transport
C1N50_20060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N50_20065	COG0765	amino acid transport
C1N50_20070	COG1126	abc transporter atp-binding protein
C1N50_20080	COG1979	alcohol dehydrogenase
C1N50_20085	COG2207	Transcriptional regulator
C1N50_20100	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C1N50_20110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N50_20125	COG3437	response regulator, receiver
C1N50_20125	COG0784	Response regulator, receiver
C1N50_20130	COG0546	phosphoglycolate phosphatase activity
C1N50_20150	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
C1N50_20155	COG0513	Belongs to the DEAD box helicase family
C1N50_20160	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C1N50_20175	COG3038	cytochrome b561
C1N50_20185	COG2116	formate transmembrane transporter activity
C1N50_20195	COG0583	DNA-binding transcription factor activity
C1N50_20205	COG3593	DNA synthesis involved in DNA repair
C1N50_20210	COG0737	Belongs to the 5'-nucleotidase family
C1N50_20215	COG0861	Integral membrane protein TerC family
C1N50_20225	COG0646	methionine synthase
C1N50_20225	COG1410	methionine synthase
C1N50_20240	COG2267	carboxylic ester hydrolase activity
C1N50_20245	COG2067	long-chain fatty acid transport protein
C1N50_20255	COG0501	Belongs to the peptidase M48B family
C1N50_20260	COG2050	protein possibly involved in aromatic compounds catabolism
C1N50_20295	COG0484	heat shock protein binding
C1N50_20305	COG3300	MHYT domain
C1N50_20305	COG5001	Diguanylate cyclase
C1N50_20310	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C1N50_20320	COG4181	ATPase activity
C1N50_20325	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C1N50_20335	COG1984	allophanate hydrolase subunit 2
C1N50_20340	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C1N50_20350	COG3447	MASE1 domain protein
C1N50_20350	COG5002	protein histidine kinase activity
C1N50_20350	COG5001	Diguanylate cyclase
C1N50_20355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1N50_20365	COG1629	transport
C1N50_20365	COG4771	TonB-dependent receptor
C1N50_20370	COG0583	DNA-binding transcription factor activity
C1N50_20375	COG1042	CoA-binding domain protein
C1N50_20375	COG0045	succinate-CoA ligase (ADP-forming) activity
C1N50_20375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N50_20395	COG0023	Translation Initiation Factor
C1N50_20530	COG3140	Belongs to the UPF0181 family
C1N50_20555	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C1N50_20560	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C1N50_20575	COG0745	RESPONSE REGULATOR receiver
C1N50_20575	COG3706	GGDEF domain
C1N50_20580	COG2203	Gaf domain
C1N50_20580	COG4251	negative regulation of phosphorylation
C1N50_20580	COG5001	Diguanylate cyclase
C1N50_20580	COG3706	GGDEF domain
C1N50_20590	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C1N50_20595	COG4149	molybdate abc transporter
C1N50_20600	COG0725	ABC transporter, periplasmic molybdate-binding protein
C1N50_20610	COG3111	PFAM Bacterial OB fold (BOF) protein
C1N50_20635	COG0534	Mate efflux family protein
C1N50_20640	COG0602	queuosine metabolic process
C1N50_20645	COG1328	CTP reductase activity
C1N50_20710	COG2197	response regulator
C1N50_20715	COG3851	Histidine kinase
C1N50_20720	COG2271	Major facilitator Superfamily
C1N50_20725	COG1482	cell wall glycoprotein biosynthetic process
C1N50_20735	COG0628	permease
C1N50_20745	COG1566	PFAM secretion protein HlyD family protein
C1N50_20770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1N50_20775	COG3118	belongs to the thioredoxin family
C1N50_20780	COG2814	Major facilitator Superfamily
C1N50_20810	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C1N50_20830	COG2116	formate transmembrane transporter activity
C1N50_20835	COG2146	nitrite reductase [NAD(P)H] activity
C1N50_20840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C1N50_20850	COG2199	diguanylate cyclase activity
C1N50_20905	COG0277	FAD linked oxidase domain protein
C1N50_20910	COG0583	DNA-binding transcription factor activity
C1N50_20915	COG1472	Belongs to the glycosyl hydrolase 3 family
C1N50_20925	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C1N50_20940	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C1N50_20950	COG1288	antiporter activity
C1N50_20960	COG3040	lipid binding
C1N50_20990	COG3469	chitinase activity
C1N50_21000	COG0419	ATPase involved in DNA repair
C1N50_21005	COG0420	3'-5' exonuclease activity
C1N50_21015	COG3209	COG3209 Rhs family protein
C1N50_21030	COG3501	Rhs element vgr protein
C1N50_21085	COG0631	protein serine/threonine phosphatase activity
C1N50_21120	COG0515	serine threonine protein kinase
C1N50_21120	COG2815	serine threonine protein kinase
C1N50_21150	COG0346	lactoylglutathione lyase activity
C1N50_21155	COG1902	pentaerythritol trinitrate reductase activity
C1N50_21165	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C1N50_21165	COG2755	lipolytic protein G-D-S-L family
C1N50_21190	COG1234	tRNA 3'-trailer cleavage
C1N50_21195	COG2067	long-chain fatty acid transport protein
C1N50_21230	COG2076	Multidrug Resistance protein
C1N50_21245	COG0671	phosphoesterase, PA-phosphatase related
C1N50_21265	COG2962	Rard protein
C1N50_21280	COG0835	chemotaxis
C1N50_21280	COG0784	Response regulator, receiver
C1N50_21285	COG0778	Nitroreductase
C1N50_21290	COG2197	response regulator
C1N50_21315	COG4771	TonB-dependent receptor
C1N50_21380	COG1522	sequence-specific DNA binding
C1N50_21415	COG0515	serine threonine protein kinase
C1N50_21440	COG3501	Rhs element vgr protein
C1N50_21455	COG2204	response regulator
C1N50_21480	COG0739	heme binding
C1N50_21485	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C1N50_21515	COG3069	C4-dicarboxylate transmembrane transporter activity
C1N50_21520	COG1704	LemA family
C1N50_21525	COG0501	Belongs to the peptidase M48B family
C1N50_21550	COG0641	radical SAM
C1N50_21570	COG3111	PFAM Bacterial OB fold (BOF) protein
C1N50_21575	COG1597	lipid kinase activity
C1N50_21580	COG0583	DNA-binding transcription factor activity
C1N50_21585	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1N50_21585	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1N50_21590	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C1N50_21600	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C1N50_21660	COG0714	Associated with various cellular activities
C1N50_21665	COG3063	Type IV pilus biogenesis stability protein PilW
C1N50_21670	COG3119	arylsulfatase activity
C1N50_21675	COG3119	arylsulfatase activity
C1N50_21705	COG2205	protein histidine kinase activity
C1N50_21705	COG2198	Histidine kinase
C1N50_21705	COG0784	Response regulator, receiver
C1N50_21710	COG1879	ABC-type sugar transport system periplasmic component
C1N50_21720	COG0210	DNA helicase
C1N50_21725	COG1289	transmembrane transporter activity
C1N50_21750	COG0789	Transcriptional regulator
C1N50_21755	COG4604	ABC transporter, ATP-binding protein
C1N50_21760	COG4605	iron ion homeostasis
C1N50_21765	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N50_21770	COG4607	ABC-type enterochelin transport system periplasmic component
C1N50_21785	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C1N50_21800	COG1609	Transcriptional regulator
C1N50_21805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N50_21810	COG1879	ABC-type sugar transport system periplasmic component
C1N50_21815	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1N50_21820	COG1129	ABC transporter
C1N50_21830	COG5001	Diguanylate cyclase
C1N50_21835	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C1N50_21860	COG0586	Pfam SNARE associated Golgi protein
C1N50_21905	COG0784	Response regulator, receiver
C1N50_21905	COG2205	protein histidine kinase activity
C1N50_21935	COG0330	HflC and HflK could
C1N50_21945	COG4175	Glycine betaine
C1N50_21945	COG0517	IMP dehydrogenase activity
C1N50_21950	COG4176	ABC-type proline glycine betaine transport system permease component
C1N50_21975	COG3706	GGDEF domain
C1N50_21995	COG2885	chlorophyll binding
C1N50_22035	COG0455	bacterial-type flagellum organization
C1N50_22045	COG4964	Belongs to the GSP D family
C1N50_22065	COG0583	DNA-binding transcription factor activity
C1N50_22070	COG1073	alpha beta
C1N50_22085	COG2801	Transposase and inactivated derivatives
C1N50_22105	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C1N50_22105	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C1N50_22120	COG4989	oxidoreductase activity
C1N50_22145	COG1914	H( )-stimulated, divalent metal cation uptake system
C1N50_22160	COG0303	'Molybdopterin
C1N50_22215	COG2897	thiosulfate sulfurtransferase activity
C1N50_22220	COG2202	Pas domain
C1N50_22220	COG2199	diguanylate cyclase activity
C1N50_22220	COG2200	EAL domain
C1N50_22245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C1N50_22250	COG0840	transmembrane signaling receptor activity
C1N50_22255	COG2814	Major facilitator Superfamily
C1N50_22260	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1N50_22275	COG1612	heme a metabolic process
C1N50_22295	COG1845	cytochrome c oxidase, subunit III
C1N50_22300	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
C1N50_22315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C1N50_22325	COG1280	lysine exporter protein (LysE YggA)
C1N50_22345	COG0179	Fumarylacetoacetate (FAA) hydrolase
C1N50_22360	COG0697	spore germination
C1N50_22380	COG2814	Major facilitator Superfamily
C1N50_22385	COG0583	DNA-binding transcription factor activity
C1N50_22390	COG5001	Diguanylate cyclase
C1N50_22395	COG0739	heme binding
C1N50_22435	COG0814	amino acid
C1N50_22455	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C1N50_22460	COG1072	(Pantothenic acid kinase))
C1N50_22470	COG1063	alcohol dehydrogenase
C1N50_22475	COG2213	PTS system mannitol-specific
C1N50_22480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N50_22485	COG0747	negative chemotaxis
C1N50_22495	COG1733	regulation of RNA biosynthetic process
C1N50_22510	COG0798	PFAM Bile acid sodium symporter
C1N50_22525	COG1881	PFAM PEBP family protein
C1N50_22535	COG0251	oxidation-reduction process
C1N50_22540	COG2706	6-phosphogluconolactonase activity
C1N50_22550	COG0800	Aldolase
C1N50_22555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N50_22560	COG4145	pantothenate transmembrane transporter activity
C1N50_22570	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
C1N50_22595	COG1131	(ABC) transporter
C1N50_22600	COG0842	Transport permease protein
C1N50_22620	COG3383	formate dehydrogenase (NAD+) activity
C1N50_22640	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N50_22650	COG1280	lysine exporter protein (LysE YggA)
C1N50_22655	COG0583	DNA-binding transcription factor activity
C1N50_22670	COG0494	nUDIX hydrolase
C1N50_22685	COG1858	cytochrome C peroxidase
C1N50_22715	COG1505	serine-type exopeptidase activity
C1N50_22720	COG0488	(ABC) transporter
C1N50_22730	COG0589	response to stress
C1N50_22740	COG0584	glycerophosphoryl diester phosphodiesterase
C1N50_22750	COG1175	transmembrane transport
C1N50_22755	COG0395	ABC-type sugar transport system, permease component
C1N50_22760	COG3842	ATPase activity
C1N50_22775	COG1846	Transcriptional regulator
C1N50_22785	COG0523	cobalamin synthesis protein
C1N50_22795	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C1N50_22805	COG4667	esterase of the alpha-beta hydrolase superfamily
C1N50_22810	COG1741	Belongs to the pirin family
C1N50_22815	COG1278	Cold shock
C1N50_22830	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C1N50_22855	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C1N50_22865	COG1686	Belongs to the peptidase S11 family
C1N50_22870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1N50_22875	COG0625	glutathione transferase activity
C1N50_22885	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C1N50_22940	COG0583	DNA-binding transcription factor activity
C1N50_22950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1N50_22955	COG1917	Cupin 2, conserved barrel domain protein
C1N50_22955	COG2207	Transcriptional regulator
C1N50_23010	COG0745	RESPONSE REGULATOR receiver
C1N50_23020	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_23045	COG3746	phosphate-selective porin O and P
C1N50_23065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N50_23110	COG0513	Belongs to the DEAD box helicase family
C1N50_23120	COG0583	DNA-binding transcription factor activity
C1N50_23140	COG1902	pentaerythritol trinitrate reductase activity
C1N50_23150	COG3853	Toxic anion resistance protein (TelA)
C1N50_23160	COG2255	four-way junction helicase activity
C1N50_23175	COG3122	Protein conserved in bacteria
C1N50_23180	COG2321	neutral zinc metallopeptidase
C1N50_23195	COG0583	DNA-binding transcription factor activity
C1N50_23215	COG0252	asparaginase activity
C1N50_23225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1N50_23225	COG0574	Belongs to the PEP-utilizing enzyme family
C1N50_23235	COG2197	response regulator
C1N50_23240	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C1N50_23250	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C1N50_23255	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C1N50_23290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1N50_23295	COG0318	PFAM AMP-dependent synthetase and ligase
C1N50_23325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N50_23335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1N50_23375	COG4948	Mandelate Racemase Muconate Lactonizing
C1N50_23395	COG1342	Belongs to the UPF0251 family
C1N50_23405	COG4176	ABC-type proline glycine betaine transport system permease component
C1N50_23410	COG3448	diguanylate cyclase activity
C1N50_23410	COG4175	Glycine betaine
C1N50_23425	COG0583	DNA-binding transcription factor activity
C1N50_23435	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C1N50_23470	COG1335	isochorismatase
C1N50_23485	COG0753	catalase activity
C1N50_23500	COG1349	DNA-binding transcription factor activity
C1N50_23505	COG0346	lactoylglutathione lyase activity
C1N50_23510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N50_23510	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N50_23520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N50_23525	COG3537	Alpha-1,2-mannosidase
C1N50_23530	COG3537	Alpha-1,2-mannosidase
C1N50_23540	COG3537	Alpha-1,2-mannosidase
C1N50_23545	COG3537	Alpha-1,2-mannosidase
C1N50_23560	COG1280	lysine exporter protein (LysE YggA)
C1N50_23565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1N50_23575	COG0583	DNA-binding transcription factor activity
C1N50_23590	COG4628	conserved protein (DUF2132)
C1N50_23595	COG0488	(ABC) transporter
C1N50_23610	COG0346	lactoylglutathione lyase activity
C1N50_23615	COG0384	phenazine biosynthesis protein PhzF
C1N50_23630	COG3220	belongs to the UPF0276 family
C1N50_23645	COG1271	oxidase subunit
C1N50_23650	COG1294	oxidase, subunit
C1N50_23690	COG2205	protein histidine kinase activity
C1N50_23695	COG0745	RESPONSE REGULATOR receiver
C1N50_23705	COG0454	-acetyltransferase
C1N50_23710	COG0148	phosphopyruvate hydratase activity
C1N50_23720	COG2814	Major facilitator Superfamily
C1N50_23730	COG2988	succinylglutamate desuccinylase activity
C1N50_23770	COG0628	permease
C1N50_23775	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C1N50_23790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1N50_23800	COG4628	conserved protein (DUF2132)
C1N50_23805	COG0583	DNA-binding transcription factor activity
C1N50_23815	COG1686	Belongs to the peptidase S11 family
C1N50_23840	COG0415	Belongs to the DNA photolyase family
C1N50_23845	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
C1N50_23855	COG4667	esterase of the alpha-beta hydrolase superfamily
C1N50_23860	COG2095	MarC family integral membrane protein
C1N50_23875	COG1596	polysaccharide export
C1N50_23880	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1N50_23915	COG1301	dicarboxylic acid transport
C1N50_23920	COG3339	Conserved Protein
C1N50_23925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1N50_23930	COG0700	Nucleoside recognition
C1N50_23935	COG3366	ferrous iron transmembrane transporter activity
C1N50_23960	COG0366	Alpha amylase catalytic
C1N50_23970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C1N50_23975	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C1N50_23980	COG1640	4-alpha-glucanotransferase
C1N50_23985	COG0058	SHG alpha-glucan phosphorylase activity
C1N50_24010	COG1999	signal sequence binding
C1N50_24020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N50_24020	COG1263	PTS System
C1N50_24025	COG1162	GTPase activity
C1N50_24030	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C1N50_24050	COG0531	amino acid
C1N50_24055	COG1982	Orn Lys Arg decarboxylase major
C1N50_24075	COG2356	endonuclease I
C1N50_24095	COG4580	involved in the transport of maltose and maltodextrins
C1N50_24105	COG2203	Gaf domain
C1N50_24105	COG2199	diguanylate cyclase activity
C1N50_24130	COG2221	Nitrite and sulphite reductase 4Fe-4S
C1N50_24135	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C1N50_24150	COG2814	Major facilitator Superfamily
C1N50_24165	COG0739	heme binding
C1N50_24180	COG0800	Aldolase
C1N50_24215	COG3121	Chaperone
C1N50_24220	COG3188	usher protein
C1N50_24250	COG0612	Peptidase, M16
C1N50_24255	COG0840	transmembrane signaling receptor activity
C1N50_24285	COG1335	isochorismatase
C1N50_24290	COG1136	(ABC) transporter
C1N50_24340	COG1764	response to oxidative stress
C1N50_24345	COG1846	Transcriptional regulator
C1N50_24350	COG0450	alkyl hydroperoxide reductase
C1N50_24355	COG3634	alkyl hydroperoxide reductase activity
C1N50_24395	COG2610	gluconate transmembrane transporter activity
C1N50_24400	COG3622	Belongs to the hyi family
C1N50_24405	COG0235	Class ii aldolase
C1N50_24410	COG3395	kinase activity
C1N50_24415	COG2084	Dehydrogenase
C1N50_24420	COG1349	DNA-binding transcription factor activity
C1N50_24440	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C1N50_24450	COG1522	sequence-specific DNA binding
C1N50_24455	COG0544	peptidyl-prolyl cis-trans isomerase activity
C1N50_24460	COG0544	peptidyl-prolyl cis-trans isomerase activity
C1N50_24465	COG0544	peptidyl-prolyl cis-trans isomerase activity
C1N50_24470	COG2207	Transcriptional regulator
C1N50_24480	COG2258	MOSC domain
C1N50_24490	COG3713	MltA-interacting MipA family protein
C1N50_24495	COG0513	Belongs to the DEAD box helicase family
C1N50_24500	COG0667	Aldo Keto reductase
C1N50_24505	COG0583	DNA-binding transcription factor activity
C1N50_24510	COG1312	Catalyzes the dehydration of D-mannonate
C1N50_24515	COG2186	Transcriptional regulator
C1N50_24525	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C1N50_24535	COG0246	Mannitol dehydrogenase
C1N50_24540	COG1904	glucuronate isomerase
C1N50_24545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N50_24550	COG0800	Aldolase
C1N50_24585	COG1132	(ABC) transporter
C1N50_24745	COG4166	transmembrane transport
C1N50_24760	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C1N50_24765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N50_24765	COG1263	PTS System
C1N50_24770	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C1N50_24795	COG1444	tRNA N-acetyltransferase activity
C1N50_24820	COG4608	Belongs to the ABC transporter superfamily
C1N50_24825	COG0444	Belongs to the ABC transporter superfamily
C1N50_24835	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C1N50_24835	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
C1N50_24860	COG0772	Belongs to the SEDS family
C1N50_24880	COG1136	(ABC) transporter
C1N50_24900	COG3275	phosphorelay sensor kinase activity
C1N50_24905	COG3279	Response regulator of the LytR AlgR family
C1N50_24915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C1N50_24935	COG0786	glutamate:sodium symporter activity
C1N50_24940	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_24975	COG1131	(ABC) transporter
C1N50_24980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N50_24985	COG0786	glutamate:sodium symporter activity
C1N50_25020	COG2259	Doxx family
C1N50_25030	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C1N50_25035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C1N50_25045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C1N50_25095	COG5001	Diguanylate cyclase
C1N50_25105	COG1609	Transcriptional regulator
C1N50_25120	COG0395	ABC-type sugar transport system, permease component
C1N50_25125	COG2723	6-phospho-beta-galactosidase activity
C1N50_25130	COG3842	ATPase activity
C1N50_25135	COG1609	Transcriptional regulator
C1N50_25145	COG0747	negative chemotaxis
C1N50_25155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N50_25160	COG0444	Belongs to the ABC transporter superfamily
C1N50_25165	COG4608	Belongs to the ABC transporter superfamily
C1N50_25175	COG1609	Transcriptional regulator
C1N50_25195	COG1472	Belongs to the glycosyl hydrolase 3 family
C1N50_25200	COG0534	Mate efflux family protein
C1N50_25205	COG0564	pseudouridine synthase activity
C1N50_25210	COG0561	phosphatase activity
C1N50_25230	COG3152	Membrane
C1N50_25245	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C1N50_25260	COG0583	DNA-binding transcription factor activity
C1N50_25310	COG2076	Multidrug Resistance protein
C1N50_25325	COG1357	PFAM Pentapeptide repeats (8 copies)
C1N50_25330	COG3047	cAMP biosynthetic process
C1N50_25340	COG2814	Major facilitator Superfamily
C1N50_25445	COG3835	regulator
C1N50_25450	COG1929	Belongs to the glycerate kinase type-1 family
C1N50_25455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N50_25515	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_25525	COG3005	denitrification pathway
C1N50_25530	COG0243	molybdopterin cofactor binding
C1N50_25535	COG0671	phosphoesterase, PA-phosphatase related
C1N50_25550	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C1N50_25555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C1N50_25560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1N50_25565	COG1116	anion transmembrane transporter activity
C1N50_25570	COG0351	phosphomethylpyrimidine kinase
C1N50_25575	COG0312	modulator of DNA gyrase
C1N50_25580	COG0312	modulator of DNA gyrase