locus-tag	class	description
DSB67_00010	COG0592	DNA-directed DNA polymerase activity
DSB67_00020	COG0187	DNA topoisomerase II activity
DSB67_00025	COG0071	Belongs to the small heat shock protein (HSP20) family
DSB67_00030	COG3977	Valine--pyruvate aminotransferase
DSB67_00045	COG2119	membrane
DSB67_00070	COG0604	alcohol dehydrogenase
DSB67_00075	COG0183	Belongs to the thiolase family
DSB67_00085	COG1739	Uncharacterized protein family UPF0029
DSB67_00090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DSB67_00140	COG0583	DNA-binding transcription factor activity
DSB67_00145	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DSB67_00150	COG2960	long-chain fatty acid transporting porin activity
DSB67_00160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSB67_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSB67_00220	COG4172	Belongs to the ABC transporter superfamily
DSB67_00225	COG4166	transmembrane transport
DSB67_00235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSB67_00280	COG0800	Aldolase
DSB67_00285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSB67_00295	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DSB67_00310	COG1522	sequence-specific DNA binding
DSB67_00315	COG5002	protein histidine kinase activity
DSB67_00315	COG5001	Diguanylate cyclase
DSB67_00330	COG0697	spore germination
DSB67_00335	COG0589	response to stress
DSB67_00340	COG1528	Iron-storage protein
DSB67_00350	COG2081	HI0933 family
DSB67_00370	COG1910	domain protein
DSB67_00385	COG1322	Protein conserved in bacteria
DSB67_00395	COG3165	ubiquinone biosynthetic process from chorismate
DSB67_00415	COG0805	protein transport
DSB67_00420	COG0084	hydrolase, TatD family'
DSB67_00440	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DSB67_00440	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DSB67_00450	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DSB67_00480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DSB67_00485	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DSB67_00495	COG2204	response regulator
DSB67_00500	COG3852	Histidine kinase
DSB67_00510	COG0174	glutamine synthetase
DSB67_00540	COG1490	D-aminoacyl-tRNA deacylase activity
DSB67_00545	COG0456	acetyltransferase
DSB67_00565	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DSB67_00570	COG3031	protein transport across the cell outer membrane
DSB67_00580	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSB67_00585	COG1459	type II secretion system
DSB67_00590	COG2165	general secretion pathway protein
DSB67_00595	COG2165	general secretion pathway protein
DSB67_00600	COG2165	general secretion pathway protein
DSB67_00605	COG4795	General secretion pathway protein
DSB67_00610	COG3156	type II secretion system protein K
DSB67_00615	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
DSB67_00620	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
DSB67_00630	COG1218	3'(2'),5'-bisphosphate nucleotidase
DSB67_00635	COG0494	nUDIX hydrolase
DSB67_00645	COG1040	competence protein
DSB67_00660	COG2183	response to ionizing radiation
DSB67_00695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DSB67_00710	COG0464	growth
DSB67_00735	COG0745	RESPONSE REGULATOR receiver
DSB67_00740	COG2205	protein histidine kinase activity
DSB67_00745	COG2233	PERMEase
DSB67_00750	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DSB67_00755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DSB67_00760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DSB67_00765	COG1758	RNA polymerase activity
DSB67_00770	COG0194	GDP metabolic process
DSB67_00785	COG0848	biopolymer transport protein
DSB67_00790	COG0811	peptide transport
DSB67_00810	COG4174	ABC transporter (Permease)
DSB67_00815	COG4239	(ABC) transporter, permease
DSB67_00820	COG0747	negative chemotaxis
DSB67_00825	COG0444	Belongs to the ABC transporter superfamily
DSB67_00830	COG4608	Belongs to the ABC transporter superfamily
DSB67_00845	COG2246	polysaccharide biosynthetic process
DSB67_00855	COG1561	YicC-like family, N-terminal region
DSB67_00860	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DSB67_00870	COG1560	Kdo2-lipid A biosynthetic process
DSB67_00880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DSB67_00915	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DSB67_00930	COG0463	Glycosyl transferase, family 2
DSB67_00935	COG0859	PFAM glycosyl transferase family 9
DSB67_00940	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DSB67_00945	COG3642	lipopolysaccharide core region biosynthetic process
DSB67_00955	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DSB67_00995	COG1519	Transferase
DSB67_01000	COG0859	PFAM glycosyl transferase family 9
DSB67_01010	COG1560	Kdo2-lipid A biosynthetic process
DSB67_01020	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DSB67_01055	COG0463	Glycosyl transferase, family 2
DSB67_01070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DSB67_01070	COG0438	transferase activity, transferring glycosyl groups
DSB67_01085	COG0438	transferase activity, transferring glycosyl groups
DSB67_01105	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSB67_01110	COG1459	type II secretion system
DSB67_01115	COG2165	general secretion pathway protein
DSB67_01165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DSB67_01200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DSB67_01205	COG0110	maltose O-acetyltransferase activity
DSB67_01210	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DSB67_01230	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DSB67_01235	COG0149	triose-phosphate isomerase activity
DSB67_01265	COG1494	fructose-1,6-bisphosphatase
DSB67_01280	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DSB67_01285	COG1575	Belongs to the MenA family. Type 1 subfamily
DSB67_01305	COG1609	Transcriptional regulator
DSB67_01310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DSB67_01330	COG0088	Forms part of the polypeptide exit tunnel
DSB67_01415	COG1841	ribosomal large subunit assembly
DSB67_01425	COG0201	protein transport
DSB67_01435	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DSB67_01440	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DSB67_01450	COG0202	RNA polymerase activity
DSB67_01455	COG0203	ribosomal protein L17
DSB67_01465	COG0545	Peptidyl-prolyl cis-trans isomerase
DSB67_01480	COG2153	protein acetylation
DSB67_01485	COG0513	Belongs to the DEAD box helicase family
DSB67_01495	COG0737	Belongs to the 5'-nucleotidase family
DSB67_01500	COG1648	precorrin-2 dehydrogenase activity
DSB67_01500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DSB67_01515	COG0471	metal ion transport
DSB67_01515	COG3273	potassium ion transport
DSB67_01520	COG0529	Catalyzes the synthesis of activated sulfate
DSB67_01540	COG1136	(ABC) transporter
DSB67_01555	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
DSB67_01565	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSB67_01575	COG2911	Protein conserved in bacteria
DSB67_01580	COG2105	PFAM AIG2 family protein
DSB67_01590	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DSB67_01600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DSB67_01605	COG0163	prenyltransferase activity
DSB67_01610	COG4143	(ABC) transporter
DSB67_01615	COG1178	ABC-type Fe3 transport system permease component
DSB67_01620	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
DSB67_01655	COG0142	geranyltranstransferase activity
DSB67_01660	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DSB67_01675	COG2966	Psort location CytoplasmicMembrane, score
DSB67_01680	COG3610	response to peptide
DSB67_01705	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DSB67_01710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSB67_01715	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DSB67_01720	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DSB67_01740	COG0473	3-isopropylmalate dehydrogenase activity
DSB67_01745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSB67_01770	COG0583	DNA-binding transcription factor activity
DSB67_01775	COG1022	Amp-dependent synthetase and ligase
DSB67_01780	COG0028	Belongs to the TPP enzyme family
DSB67_01785	COG0440	acetolactate synthase activity
DSB67_01800	COG0469	pyruvate kinase activity
DSB67_01805	COG1349	DNA-binding transcription factor activity
DSB67_01810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DSB67_01850	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DSB67_01855	COG0358	DNA primase activity
DSB67_01860	COG1610	YqeY-like protein
DSB67_01865	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DSB67_01870	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DSB67_01875	COG0596	Alpha beta hydrolase
DSB67_01885	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DSB67_01890	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DSB67_01905	COG3267	Type II secretory pathway component ExeA
DSB67_01905	COG3409	Peptidoglycan-binding domain 1 protein
DSB67_01915	COG4991	sh3 domain protein
DSB67_01920	COG0306	phosphate transporter
DSB67_01925	COG1392	Phosphate transport regulator
DSB67_01930	COG3025	triphosphatase activity
DSB67_01935	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DSB67_01945	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DSB67_01955	COG1538	Outer membrane efflux protein
DSB67_01960	COG0494	nUDIX hydrolase
DSB67_01965	COG3151	Protein conserved in bacteria
DSB67_01975	COG3150	esterase
DSB67_01980	COG0187	DNA topoisomerase II activity
DSB67_01985	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DSB67_01990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSB67_01995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSB67_02000	COG3105	Protein conserved in bacteria
DSB67_02010	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DSB67_02030	COG0723	plastoquinol--plastocyanin reductase activity
DSB67_02035	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DSB67_02040	COG2857	Cytochrome c1
DSB67_02045	COG0625	glutathione transferase activity
DSB67_02050	COG2969	positive regulation of protein catabolic process
DSB67_02055	COG2823	Periplasmic or secreted lipoprotein
DSB67_02060	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DSB67_02075	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DSB67_02095	COG3116	cell division
DSB67_02100	COG0768	penicillin binding
DSB67_02105	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DSB67_02110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DSB67_02125	COG0772	Belongs to the SEDS family
DSB67_02140	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DSB67_02145	COG0849	cell division
DSB67_02150	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DSB67_02170	COG0494	nUDIX hydrolase
DSB67_02180	COG0505	Belongs to the CarA family
DSB67_02190	COG0730	response to heat
DSB67_02195	COG0583	DNA-binding transcription factor activity
DSB67_02200	COG2860	membrane
DSB67_02225	COG0493	'glutamate synthase
DSB67_02230	COG0070	glutamate synthase
DSB67_02230	COG0069	glutamate synthase activity
DSB67_02230	COG0067	glutamate synthase
DSB67_02240	COG0070	glutamate synthase
DSB67_02240	COG0069	glutamate synthase activity
DSB67_02240	COG0067	glutamate synthase
DSB67_02245	COG1242	4 iron, 4 sulfur cluster binding
DSB67_02250	COG2203	Gaf domain
DSB67_02250	COG5001	Diguanylate cyclase
DSB67_02250	COG4251	negative regulation of phosphorylation
DSB67_02250	COG3706	GGDEF domain
DSB67_02260	COG0784	Response regulator, receiver
DSB67_02260	COG2198	Histidine kinase
DSB67_02260	COG5002	protein histidine kinase activity
DSB67_02270	COG0745	RESPONSE REGULATOR receiver
DSB67_02285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DSB67_02300	COG0083	homoserine kinase activity
DSB67_02305	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DSB67_02335	COG1115	amino acid carrier protein
DSB67_02340	COG3022	response to hydroperoxide
DSB67_02350	COG0513	Belongs to the DEAD box helicase family
DSB67_02365	COG0716	FMN binding
DSB67_02375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DSB67_02380	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DSB67_02405	COG0667	Aldo Keto reductase
DSB67_02430	COG0730	response to heat
DSB67_02445	COG1283	sodium-dependent phosphate transmembrane transporter activity
DSB67_02450	COG0583	DNA-binding transcription factor activity
DSB67_02455	COG0640	Transcriptional regulator
DSB67_02460	COG0268	Binds directly to 16S ribosomal RNA
DSB67_02465	COG0728	peptidoglycan biosynthetic process
DSB67_02470	COG0196	riboflavin kinase activity
DSB67_02485	COG1047	Peptidyl-prolyl cis-trans
DSB67_02490	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DSB67_02495	COG3279	Response regulator of the LytR AlgR family
DSB67_02500	COG3275	phosphorelay sensor kinase activity
DSB67_02505	COG1966	Carbon starvation protein
DSB67_02525	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DSB67_02530	COG1472	Belongs to the glycosyl hydrolase 3 family
DSB67_02535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DSB67_02540	COG1605	Chorismate mutase
DSB67_02540	COG0287	Prephenate dehydrogenase
DSB67_02545	COG0739	heme binding
DSB67_02555	COG0488	(ABC) transporter
DSB67_02570	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
DSB67_02575	COG1605	Chorismate mutase
DSB67_02575	COG0077	Prephenate dehydratase
DSB67_02580	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DSB67_02585	COG0741	lytic transglycosylase activity
DSB67_02590	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DSB67_02595	COG0564	pseudouridine synthase activity
DSB67_02605	COG0542	response to heat
DSB67_02665	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DSB67_02680	COG0745	RESPONSE REGULATOR receiver
DSB67_02685	COG5002	protein histidine kinase activity
DSB67_02695	COG0248	Ppx GppA phosphatase
DSB67_02700	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DSB67_02705	COG0573	inorganic phosphate transmembrane transporter activity
DSB67_02710	COG0581	inorganic phosphate transmembrane transporter activity
DSB67_02715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DSB67_02720	COG0704	Plays a role in the regulation of phosphate uptake
DSB67_02735	COG0450	alkyl hydroperoxide reductase
DSB67_02740	COG0583	DNA-binding transcription factor activity
DSB67_02745	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DSB67_02755	COG0517	IMP dehydrogenase activity
DSB67_02775	COG1862	Preprotein translocase
DSB67_02780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DSB67_02785	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DSB67_02790	COG0483	inositol monophosphate 1-phosphatase activity
DSB67_02795	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
DSB67_02810	COG0822	iron-sulfur transferase activity
DSB67_02815	COG0316	Belongs to the HesB IscA family
DSB67_02830	COG0633	Ferredoxin
DSB67_02835	COG2975	iron-sulfur cluster assembly
DSB67_02870	COG2976	Protein conserved in bacteria
DSB67_02875	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DSB67_02890	COG2199	diguanylate cyclase activity
DSB67_02890	COG2203	Gaf domain
DSB67_02905	COG0516	GMP reductase activity
DSB67_02905	COG0517	IMP dehydrogenase activity
DSB67_02925	COG1584	GPR1 FUN34 yaaH family protein
DSB67_02930	COG1115	amino acid carrier protein
DSB67_02940	COG0583	DNA-binding transcription factor activity
DSB67_02945	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DSB67_02950	COG0668	transmembrane transport
DSB67_02965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DSB67_02990	COG0583	DNA-binding transcription factor activity
DSB67_03005	COG2867	negative regulation of translational initiation
DSB67_03010	COG2914	Belongs to the UPF0125 (RnfH) family
DSB67_03015	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DSB67_03020	COG0456	acetyltransferase
DSB67_03025	COG0497	DNA recombination
DSB67_03040	COG1301	dicarboxylic acid transport
DSB67_03080	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DSB67_03090	COG0590	tRNA wobble adenosine to inosine editing
DSB67_03105	COG0047	phosphoribosylformylglycinamidine synthase activity
DSB67_03105	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DSB67_03135	COG2195	Cleaves the N-terminal amino acid of tripeptides
DSB67_03140	COG2252	PERMEase
DSB67_03165	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DSB67_03170	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DSB67_03175	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DSB67_03175	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DSB67_03200	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DSB67_03205	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DSB67_03215	COG0142	geranyltranstransferase activity
DSB67_03225	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DSB67_03240	COG0583	DNA-binding transcription factor activity
DSB67_03250	COG2363	Small membrane protein
DSB67_03270	COG1611	Belongs to the LOG family
DSB67_03275	COG0745	RESPONSE REGULATOR receiver
DSB67_03275	COG3706	GGDEF domain
DSB67_03295	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
DSB67_03310	COG1464	Belongs to the NlpA lipoprotein family
DSB67_03315	COG2011	ABC-type metal ion transport system permease component
DSB67_03320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DSB67_03325	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DSB67_03335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSB67_03335	COG1263	PTS System
DSB67_03340	COG0366	Alpha amylase catalytic
DSB67_03345	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DSB67_03350	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DSB67_03370	COG1686	Belongs to the peptidase S11 family
DSB67_03375	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DSB67_03380	COG0772	Belongs to the SEDS family
DSB67_03385	COG0768	penicillin binding
DSB67_03395	COG0799	negative regulation of ribosome biogenesis
DSB67_03400	COG1466	dna polymerase III delta subunit
DSB67_03405	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
DSB67_03415	COG2888	peptidyl-tyrosine sulfation
DSB67_03420	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DSB67_03425	COG4535	Mg2 and Co2 transporter CorC
DSB67_03435	COG1702	phosphate starvation-inducible protein PhoH
DSB67_03450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DSB67_03575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DSB67_03600	COG2890	protein-(glutamine-N5) methyltransferase activity
DSB67_03605	COG3094	Invasion gene expression up-regulator, SirB
DSB67_03610	COG2912	Transglutaminase-like superfamily
DSB67_03620	COG0737	Belongs to the 5'-nucleotidase family
DSB67_03625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DSB67_03630	COG1187	pseudouridine synthase activity
DSB67_03635	COG2840	Smr protein MutS2
DSB67_03680	COG2608	mercury ion transmembrane transporter activity
DSB67_03680	COG2217	Heavy metal translocating P-type atpase
DSB67_03690	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
DSB67_03750	COG0835	chemotaxis
DSB67_03750	COG0784	Response regulator, receiver
DSB67_03755	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DSB67_03760	COG1815	bacterial-type flagellum-dependent cell motility
DSB67_03765	COG1558	bacterial-type flagellum-dependent cell motility
DSB67_03770	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DSB67_03775	COG1749	Flagellar hook protein flgE
DSB67_03780	COG4787	bacterial-type flagellum-dependent cell motility
DSB67_03785	COG4786	Flagellar basal body rod
DSB67_03790	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DSB67_03795	COG1706	bacterial-type flagellum-dependent cell motility
DSB67_03800	COG1705	Flagellar rod assembly protein muramidase FlgJ
DSB67_03800	COG3951	Flagellar rod assembly protein muramidase FlgJ
DSB67_03815	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DSB67_03820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DSB67_03825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DSB67_03830	COG2190	(PTS) system
DSB67_03835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DSB67_03840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSB67_03850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DSB67_03855	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
DSB67_03890	COG0330	HflC and HflK could
DSB67_03895	COG3118	belongs to the thioredoxin family
DSB67_03905	COG0300	oxidoreductase activity
DSB67_03910	COG1090	epimerase
DSB67_03920	COG0622	Phosphoesterase
DSB67_03940	COG3710	Transcriptional regulator
DSB67_03955	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DSB67_03960	COG3104	oligopeptide transport
DSB67_03970	COG0367	asparagine synthase
DSB67_03975	COG4651	solute:proton antiporter activity
DSB67_03975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DSB67_03980	COG1846	Transcriptional regulator
DSB67_03980	COG1940	carbohydrate kinase activity
DSB67_03985	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DSB67_03995	COG1263	PTS System
DSB67_03995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSB67_03995	COG2190	(PTS) system
DSB67_04010	COG0735	belongs to the Fur family
DSB67_04030	COG0596	Alpha beta hydrolase
DSB67_04040	COG0033	Phosphoglucomutase
DSB67_04055	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DSB67_04065	COG2009	succinate dehydrogenase
DSB67_04070	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DSB67_04075	COG1053	succinate dehydrogenase
DSB67_04085	COG0567	Dehydrogenase, E1 component
DSB67_04090	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSB67_04105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DSB67_04110	COG1121	(ABC) transporter
DSB67_04115	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
DSB67_04120	COG4977	sequence-specific DNA binding
DSB67_04125	COG1918	ferrous iron import across plasma membrane
DSB67_04160	COG3102	Protein conserved in bacteria
DSB67_04175	COG0788	formyltetrahydrofolate deformylase activity
DSB67_04180	COG1199	ATP-dependent helicase activity
DSB67_04185	COG1214	PFAM Peptidase M22, glycoprotease
DSB67_04195	COG3065	identical protein binding
DSB67_04200	COG2267	carboxylic ester hydrolase activity
DSB67_04205	COG0318	PFAM AMP-dependent synthetase and ligase
DSB67_04210	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DSB67_04215	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DSB67_04220	COG2894	cell division
DSB67_04235	COG2951	lytic endotransglycosylase activity
DSB67_04245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DSB67_04250	COG2852	Protein conserved in bacteria
DSB67_04305	COG1028	Short-chain dehydrogenase reductase Sdr
DSB67_04315	COG1169	isochorismate synthase
DSB67_04320	COG1021	2,3-dihydroxybenzoate-AMP ligase
DSB67_04325	COG1535	isochorismatase
DSB67_04325	COG3433	isochorismatase activity
DSB67_04330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DSB67_04330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DSB67_04340	COG2977	Belongs to the P-Pant transferase superfamily
DSB67_04345	COG4771	TonB-dependent receptor
DSB67_04355	COG0513	Belongs to the DEAD box helicase family
DSB67_04360	COG0569	domain protein
DSB67_04365	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DSB67_04385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSB67_04390	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DSB67_04395	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DSB67_04430	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DSB67_04435	COG0776	regulation of translation
DSB67_04440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSB67_04445	COG1555	photosystem II stabilization
DSB67_04465	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
DSB67_04470	COG0436	Aminotransferase
DSB67_04475	COG1169	isochorismate synthase
DSB67_04485	COG0596	Alpha beta hydrolase
DSB67_04490	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DSB67_04495	COG1441	menaquinone biosynthetic process
DSB67_04505	COG1263	PTS System
DSB67_04505	COG2190	(PTS) system
DSB67_04505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSB67_04510	COG0583	DNA-binding transcription factor activity
DSB67_04515	COG2855	membrane
DSB67_04580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSB67_04600	COG1522	sequence-specific DNA binding
DSB67_04605	COG1946	Acyl-CoA thioesterase
DSB67_04610	COG3126	Type III secretion system lipoprotein chaperone (YscW)
DSB67_04625	COG3706	GGDEF domain
DSB67_04635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DSB67_04640	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DSB67_04645	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DSB67_04650	COG0517	IMP dehydrogenase activity
DSB67_04650	COG0516	GMP reductase activity
DSB67_04660	COG2217	Heavy metal translocating P-type atpase
DSB67_04680	COG0537	adenosine 5'-monophosphoramidase activity
DSB67_04710	COG1252	NADH dehydrogenase
DSB67_04725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DSB67_04735	COG4591	ABC-type transport system involved in lipoprotein release permease component
DSB67_04740	COG1136	(ABC) transporter
DSB67_04745	COG4591	ABC-type transport system involved in lipoprotein release permease component
DSB67_04755	COG0658	competence protein
DSB67_04755	COG2333	competence protein COMEC
DSB67_04760	COG1132	(ABC) transporter
DSB67_04780	COG2719	SpoVR family
DSB67_04785	COG2718	Belongs to the UPF0229 family
DSB67_04790	COG2766	serine protein kinase
DSB67_04810	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DSB67_04820	COG1882	Formate acetyltransferase
DSB67_04845	COG4215	(ABC) transporter
DSB67_04855	COG0708	Exodeoxyribonuclease III
DSB67_04865	COG3923	Primosomal replication protein n
DSB67_04870	COG0730	response to heat
DSB67_04875	COG1199	ATP-dependent helicase activity
DSB67_04885	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
DSB67_04890	COG1187	pseudouridine synthase activity
DSB67_04900	COG1278	Cold shock
DSB67_04910	COG0542	response to heat
DSB67_04915	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DSB67_04945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DSB67_04950	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DSB67_04955	COG0297	glycogen (starch) synthase activity
DSB67_04975	COG3070	regulator of competence-specific genes
DSB67_04990	COG0745	RESPONSE REGULATOR receiver
DSB67_04995	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DSB67_05000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DSB67_05010	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
DSB67_05015	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DSB67_05020	COG3568	Endonuclease Exonuclease Phosphatase
DSB67_05035	COG0189	ligase activity
DSB67_05035	COG4067	protein conserved in archaea
DSB67_05050	COG1801	Protein of unknown function DUF72
DSB67_05065	COG0840	transmembrane signaling receptor activity
DSB67_05070	COG0632	four-way junction helicase activity
DSB67_05080	COG1271	oxidase subunit
DSB67_05085	COG1294	oxidase, subunit
DSB67_05090	COG4890	Cyd operon protein YbgT
DSB67_05100	COG0824	Thioesterase
DSB67_05105	COG0811	peptide transport
DSB67_05120	COG0823	Involved in the tonB-independent uptake of proteins
DSB67_05125	COG2885	chlorophyll binding
DSB67_05145	COG3766	membrane
DSB67_05155	COG0754	glutathionylspermidine amidase activity
DSB67_05165	COG0784	Response regulator, receiver
DSB67_05165	COG2205	protein histidine kinase activity
DSB67_05230	COG0456	acetyltransferase
DSB67_05330	COG4669	(LipO)protein
DSB67_05360	COG3177	Filamentation induced by cAMP protein fic
DSB67_05370	COG0583	DNA-binding transcription factor activity
DSB67_05375	COG4792	protein secretion
DSB67_05380	COG4791	protein targeting
DSB67_05385	COG4794	Type iii secretion
DSB67_05390	COG4790	Type iii secretion
DSB67_05395	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DSB67_05460	COG0457	Tetratricopeptide repeat
DSB67_05515	COG2824	Alkylphosphonate utilization operon protein PhnA
DSB67_05525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSB67_05530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSB67_05545	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DSB67_05565	COG3568	Endonuclease Exonuclease Phosphatase
DSB67_05585	COG0402	S-adenosylhomocysteine deaminase activity
DSB67_05610	COG0583	DNA-binding transcription factor activity
DSB67_05620	COG0686	Belongs to the AlaDH PNT family
DSB67_05630	COG1674	ftsk spoiiie
DSB67_05640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DSB67_05650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DSB67_05670	COG2226	methyltransferase
DSB67_05695	COG0300	oxidoreductase activity
DSB67_05710	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DSB67_05730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DSB67_05750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DSB67_05760	COG1757	Na H antiporter
DSB67_05770	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DSB67_05780	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DSB67_05780	COG0131	Imidazoleglycerol-phosphate dehydratase
DSB67_05785	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DSB67_05790	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DSB67_05795	COG0107	imidazoleglycerol-phosphate synthase activity
DSB67_05800	COG0140	phosphoribosyl-ATP diphosphatase activity
DSB67_05800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DSB67_05805	COG3012	SEC-C Motif Domain Protein
DSB67_05810	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DSB67_05815	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSB67_05820	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DSB67_05825	COG0215	cysteine-tRNA ligase activity
DSB67_05830	COG1435	thymidine kinase activity
DSB67_05835	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DSB67_05855	COG2116	formate transmembrane transporter activity
DSB67_05860	COG0390	transport system, permease component
DSB67_05865	COG4459	periplasmic nitrate reductase
DSB67_05870	COG3005	denitrification pathway
DSB67_05875	COG0243	molybdopterin cofactor binding
DSB67_05890	COG1121	(ABC) transporter
DSB67_05895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DSB67_05900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DSB67_05905	COG1227	inorganic diphosphatase activity
DSB67_05915	COG4172	Belongs to the ABC transporter superfamily
DSB67_05925	COG4171	peptide transport system, permease
DSB67_05930	COG4168	peptide transport system, permease
DSB67_05940	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DSB67_05945	COG1842	Phage shock protein A
DSB67_05955	COG1983	PspC domain protein
DSB67_05965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSB67_05975	COG2818	Glycosylase
DSB67_05995	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DSB67_06000	COG0626	cystathionine gamma-synthase activity
DSB67_06010	COG0733	neurotransmitter:sodium symporter activity
DSB67_06015	COG0564	pseudouridine synthase activity
DSB67_06025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DSB67_06030	COG1151	hydroxylamine reductase activity
DSB67_06035	COG3604	Transcriptional regulator
DSB67_06040	COG2814	Major facilitator Superfamily
DSB67_06050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DSB67_06055	COG4136	ATPase activity
DSB67_06060	COG4135	transport system, permease component
DSB67_06065	COG4134	Bacterial extracellular solute-binding protein
DSB67_06080	COG0659	secondary active sulfate transmembrane transporter activity
DSB67_06090	COG3313	Fe-S protein
DSB67_06135	COG2205	protein histidine kinase activity
DSB67_06140	COG0745	RESPONSE REGULATOR receiver
DSB67_06150	COG1061	Type III restriction enzyme res subunit
DSB67_06155	COG1187	pseudouridine synthase activity
DSB67_06160	COG2814	Major facilitator Superfamily
DSB67_06175	COG0702	epimerase
DSB67_06180	COG0534	Mate efflux family protein
DSB67_06185	COG4181	ATPase activity
DSB67_06215	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DSB67_06225	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DSB67_06235	COG1737	Transcriptional regulator
DSB67_06240	COG0076	glutamate decarboxylase activity
DSB67_06250	COG2431	L-lysine efflux transmembrane transporter activity
DSB67_06270	COG3070	regulator of competence-specific genes
DSB67_06285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSB67_06285	COG4191	Histidine kinase
DSB67_06295	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DSB67_06330	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DSB67_06335	COG4988	ABC transporter
DSB67_06340	COG0492	ferredoxin-NADP+ reductase activity
DSB67_06345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DSB67_06360	COG0745	RESPONSE REGULATOR receiver
DSB67_06360	COG3706	GGDEF domain
DSB67_06365	COG0471	metal ion transport
DSB67_06370	COG2949	membrane
DSB67_06380	COG1643	Atp-dependent helicase
DSB67_06440	COG0277	FAD linked oxidase domain protein
DSB67_06440	COG0247	lactate metabolic process
DSB67_06485	COG2986	histidine ammonia-lyase
DSB67_06495	COG0010	Belongs to the arginase family
DSB67_06505	COG2188	Transcriptional regulator
DSB67_06540	COG0641	radical SAM
DSB67_06545	COG3119	arylsulfatase activity
DSB67_06560	COG0251	oxidation-reduction process
DSB67_06600	COG3706	GGDEF domain
DSB67_06610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSB67_06610	COG0072	phenylalanine-tRNA ligase activity
DSB67_06615	COG1535	isochorismatase
DSB67_06615	COG3433	isochorismatase activity
DSB67_06635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DSB67_06645	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DSB67_06650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DSB67_06655	COG4774	siderophore transport
DSB67_06660	COG4607	ABC-type enterochelin transport system periplasmic component
DSB67_06665	COG4605	iron ion homeostasis
DSB67_06670	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DSB67_06715	COG1346	cytolysis
DSB67_06725	COG2925	Exonuclease
DSB67_06740	COG0702	epimerase
DSB67_06750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DSB67_06760	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DSB67_06770	COG2062	phosphohistidine phosphatase, SixA
DSB67_06785	COG4139	cobalamin transport
DSB67_06815	COG0583	DNA-binding transcription factor activity
DSB67_06825	COG1451	nucleotide metabolic process
DSB67_06900	COG0726	polysaccharide deacetylase
DSB67_06910	COG2195	Cleaves the N-terminal amino acid of tripeptides
DSB67_06925	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DSB67_06935	COG0625	glutathione transferase activity
DSB67_06990	COG0318	PFAM AMP-dependent synthetase and ligase
DSB67_07005	COG0668	transmembrane transport
DSB67_07010	COG3247	response to pH
DSB67_07025	COG1846	Transcriptional regulator
DSB67_07040	COG0693	protein deglycase activity
DSB67_07080	COG2205	protein histidine kinase activity
DSB67_07080	COG4999	Histidine kinase
DSB67_07080	COG3850	Histidine kinase
DSB67_07080	COG3437	response regulator, receiver
DSB67_07085	COG3300	MHYT domain
DSB67_07085	COG5001	Diguanylate cyclase
DSB67_07115	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DSB67_07120	COG1215	transferase activity, transferring glycosyl groups
DSB67_07125	COG0438	transferase activity, transferring glycosyl groups
DSB67_07160	COG0438	transferase activity, transferring glycosyl groups
DSB67_07165	COG2204	response regulator
DSB67_07185	COG2885	chlorophyll binding
DSB67_07195	COG1793	dna ligase
DSB67_07205	COG0534	Mate efflux family protein
DSB67_07210	COG0307	riboflavin synthase, alpha
DSB67_07225	COG2201	protein-glutamate methylesterase activity
DSB67_07230	COG3706	GGDEF domain
DSB67_07240	COG0791	NLP P60 protein
DSB67_07300	COG1940	carbohydrate kinase activity
DSB67_07310	COG0303	'Molybdopterin
DSB67_07320	COG3842	ATPase activity
DSB67_07325	COG4662	Binding-protein-dependent transport system inner membrane component
DSB67_07335	COG2204	response regulator
DSB67_07340	COG4191	Histidine kinase
DSB67_07360	COG0488	(ABC) transporter
DSB67_07365	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DSB67_07385	COG3381	protein complex oligomerization
DSB67_07395	COG3383	formate dehydrogenase (NAD+) activity
DSB67_07395	COG0243	molybdopterin cofactor binding
DSB67_07400	COG0437	4 iron, 4 sulfur cluster binding
DSB67_07415	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DSB67_07420	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DSB67_07425	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DSB67_07430	COG1177	transmembrane transport
DSB67_07435	COG1176	ABC-type spermidine putrescine transport system, permease component I
DSB67_07440	COG3842	ATPase activity
DSB67_07470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSB67_07485	COG2217	Heavy metal translocating P-type atpase
DSB67_07495	COG2010	Cytochrome c
DSB67_07510	COG3278	Belongs to the heme-copper respiratory oxidase family
DSB67_07675	COG1067	ATP-dependent peptidase activity
DSB67_07725	COG2902	Dehydrogenase
DSB67_07735	COG0308	aminopeptidase N
DSB67_07750	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
DSB67_07755	COG1956	GAF domain-containing protein
DSB67_07760	COG1132	(ABC) transporter
DSB67_07765	COG2995	paraquat-inducible protein a
DSB67_07770	COG3008	intermembrane lipid transfer
DSB67_07795	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DSB67_07815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSB67_07820	COG4597	amino acid ABC transporter
DSB67_07825	COG0765	amino acid transport
DSB67_07830	COG1126	abc transporter atp-binding protein
DSB67_07835	COG0670	Belongs to the BI1 family
DSB67_07840	COG2920	part of a sulfur-relay system
DSB67_07845	COG1254	Belongs to the acylphosphatase family
DSB67_07850	COG0840	transmembrane signaling receptor activity
DSB67_07905	COG3706	GGDEF domain
DSB67_07915	COG0602	queuosine metabolic process
DSB67_07920	COG0561	phosphatase activity
DSB67_07955	COG2828	Protein conserved in bacteria
DSB67_07965	COG0372	Belongs to the citrate synthase family
DSB67_07970	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DSB67_07980	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DSB67_07995	COG1030	water channel activity
DSB67_08180	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DSB67_08190	COG0484	heat shock protein binding
DSB67_08245	COG1403	HNH endonuclease
DSB67_08265	COG1802	Transcriptional regulator
DSB67_08265	COG4626	Terminase
DSB67_08305	COG0582	viral genome integration into host DNA
DSB67_08380	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DSB67_08380	COG0517	IMP dehydrogenase activity
DSB67_08455	COG1012	belongs to the aldehyde dehydrogenase family
DSB67_08460	COG3284	Transcriptional regulator
DSB67_08465	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DSB67_08470	COG0363	glucosamine-6-phosphate deaminase activity
DSB67_08475	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DSB67_08480	COG4565	transcriptional regulatory protein
DSB67_08485	COG3290	protein histidine kinase activity
DSB67_08500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSB67_08540	COG0454	-acetyltransferase
DSB67_08575	COG1280	lysine exporter protein (LysE YggA)
DSB67_08585	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DSB67_08590	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DSB67_08635	COG1404	Belongs to the peptidase S8 family
DSB67_08655	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DSB67_08665	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DSB67_08675	COG0215	cysteine-tRNA ligase activity
DSB67_08690	COG1368	sulfuric ester hydrolase activity
DSB67_08715	COG1115	amino acid carrier protein
DSB67_08750	COG1280	lysine exporter protein (LysE YggA)
DSB67_08770	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DSB67_08790	COG1560	Kdo2-lipid A biosynthetic process
DSB67_08795	COG1280	lysine exporter protein (LysE YggA)
DSB67_08830	COG3063	Type IV pilus biogenesis stability protein PilW
DSB67_08855	COG1643	Atp-dependent helicase
DSB67_08895	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DSB67_08905	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DSB67_08945	COG3227	Zinc metalloprotease (Elastase)
DSB67_08975	COG3706	GGDEF domain
DSB67_08985	COG0443	Heat shock 70 kDa protein
DSB67_08990	COG0443	Heat shock 70 kDa protein
DSB67_09015	COG0583	DNA-binding transcription factor activity
DSB67_09025	COG1132	(ABC) transporter
DSB67_09030	COG1132	(ABC) transporter
DSB67_09040	COG4774	siderophore transport
DSB67_09045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DSB67_09050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DSB67_09055	COG1120	ATPase activity
DSB67_09070	COG0814	amino acid
DSB67_09075	COG1454	alcohol dehydrogenase
DSB67_09080	COG4221	oxidoreductase activity
DSB67_09085	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DSB67_09095	COG0861	Integral membrane protein TerC family
DSB67_09105	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DSB67_09110	COG1328	CTP reductase activity
DSB67_09115	COG1280	lysine exporter protein (LysE YggA)
DSB67_09135	COG0456	acetyltransferase
DSB67_09165	COG3340	Belongs to the peptidase S51 family
DSB67_09255	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DSB67_09255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DSB67_09285	COG1280	lysine exporter protein (LysE YggA)
DSB67_09455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSB67_09470	COG3106	COG3106 Predicted ATPase
DSB67_09485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DSB67_09490	COG0784	Response regulator, receiver
DSB67_09490	COG2205	protein histidine kinase activity
DSB67_09505	COG0814	amino acid
DSB67_09510	COG1760	l-serine dehydratase
DSB67_09515	COG3300	MHYT domain
DSB67_09515	COG5001	Diguanylate cyclase
DSB67_09525	COG2197	response regulator
DSB67_09530	COG0720	synthase
DSB67_09540	COG0017	Asparaginyl-tRNA synthetase
DSB67_09555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSB67_09575	COG1448	Aminotransferase
DSB67_09595	COG0840	transmembrane signaling receptor activity
DSB67_09600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DSB67_09605	COG1846	Transcriptional regulator
DSB67_09645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSB67_09650	COG3108	Peptidase M15
DSB67_09655	COG2989	Protein conserved in bacteria
DSB67_09705	COG1138	Cytochrome C-type biogenesis protein
DSB67_09735	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DSB67_09740	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DSB67_09750	COG1546	Belongs to the CinA family
DSB67_09750	COG1058	Belongs to the CinA family
DSB67_09765	COG0019	diaminopimelate decarboxylase activity
DSB67_09805	COG0322	excinuclease ABC activity
DSB67_09810	COG2197	response regulator
DSB67_09815	COG0417	DNA replication proofreading
DSB67_09835	COG1187	pseudouridine synthase activity
DSB67_09845	COG0009	L-threonylcarbamoyladenylate synthase
DSB67_09850	COG0613	PHP domain protein
DSB67_09860	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DSB67_09865	COG0512	Glutamine amidotransferase of anthranilate synthase
DSB67_09875	COG0135	phosphoribosylanthranilate isomerase activity
DSB67_09875	COG0134	indole-3-glycerol-phosphate synthase activity
DSB67_09885	COG0159	tryptophan synthase activity
DSB67_09890	COG1301	dicarboxylic acid transport
DSB67_09910	COG1607	acyl-coa hydrolase
DSB67_09915	COG2350	Protein conserved in bacteria
DSB67_09930	COG0583	DNA-binding transcription factor activity
DSB67_09945	COG5001	Diguanylate cyclase
DSB67_09945	COG1716	ATPase activity
DSB67_09950	COG1032	radical SAM domain protein
DSB67_10000	COG2175	clavaminate synthase activity
DSB67_10015	COG0840	transmembrane signaling receptor activity
DSB67_10025	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DSB67_10030	COG0463	Glycosyl transferase, family 2
DSB67_10035	COG0745	RESPONSE REGULATOR receiver
DSB67_10040	COG5002	protein histidine kinase activity
DSB67_10040	COG3850	Histidine kinase
DSB67_10075	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DSB67_10095	COG3708	Transcriptional regulator
DSB67_10095	COG2207	Transcriptional regulator
DSB67_10115	COG2176	DNA-directed DNA polymerase activity
DSB67_10135	COG1136	(ABC) transporter
DSB67_10135	COG0577	efflux transmembrane transporter activity
DSB67_10140	COG1136	(ABC) transporter
DSB67_10140	COG0577	efflux transmembrane transporter activity
DSB67_10145	COG0577	efflux transmembrane transporter activity
DSB67_10155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSB67_10180	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DSB67_10190	COG3118	belongs to the thioredoxin family
DSB67_10210	COG2995	paraquat-inducible protein a
DSB67_10215	COG3008	intermembrane lipid transfer
DSB67_10215	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DSB67_10220	COG3009	Protein conserved in bacteria
DSB67_10235	COG4166	transmembrane transport
DSB67_10245	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DSB67_10250	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
DSB67_10260	COG0539	negative regulation of cytoplasmic translation
DSB67_10270	COG0616	signal peptide processing
DSB67_10275	COG1028	Short-chain dehydrogenase reductase Sdr
DSB67_10295	COG0784	Response regulator, receiver
DSB67_10295	COG0835	chemotaxis
DSB67_10300	COG1940	carbohydrate kinase activity
DSB67_10315	COG4667	esterase of the alpha-beta hydrolase superfamily
DSB67_10330	COG0733	neurotransmitter:sodium symporter activity
DSB67_10350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSB67_10350	COG1263	PTS System
DSB67_10355	COG0084	hydrolase, TatD family'
DSB67_10370	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DSB67_10400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DSB67_10415	COG1399	metal-binding, possibly nucleic acid-binding protein
DSB67_10420	COG0424	maF-like protein
DSB67_10425	COG0564	pseudouridine synthase activity
DSB67_10430	COG1530	ribonuclease E activity
DSB67_10440	COG0659	secondary active sulfate transmembrane transporter activity
DSB67_10445	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DSB67_10450	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
DSB67_10480	COG2186	Transcriptional regulator
DSB67_10490	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DSB67_10495	COG0653	protein targeting
DSB67_10500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DSB67_10505	COG2199	diguanylate cyclase activity
DSB67_10515	COG1122	ATPase activity
DSB67_10520	COG4120	Belongs to the binding-protein-dependent transport system permease family
DSB67_10540	COG0280	phosphate acetyltransferase
DSB67_10540	COG0857	belongs to the CobB CobQ family
DSB67_10545	COG0435	Glutathione S-transferase
DSB67_10555	COG0444	Belongs to the ABC transporter superfamily
DSB67_10560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSB67_10565	COG0601	transmembrane transport
DSB67_10575	COG0314	molybdopterin synthase activity
DSB67_10580	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DSB67_10590	COG0521	Mo-molybdopterin cofactor biosynthetic process
DSB67_10595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DSB67_10600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DSB67_10615	COG0556	nucleotide-excision repair
DSB67_10675	COG1882	Formate acetyltransferase
DSB67_10680	COG4657	Part of a membrane complex involved in electron transport
DSB67_10690	COG4656	Part of a membrane complex involved in electron transport
DSB67_10695	COG4658	electron transport chain
DSB67_10700	COG4659	FMN binding
DSB67_10705	COG4660	Part of a membrane complex involved in electron transport
DSB67_10710	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DSB67_10715	COG0346	lactoylglutathione lyase activity
DSB67_10725	COG2885	chlorophyll binding
DSB67_10735	COG2056	Na+-H+ antiporter family
DSB67_10750	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DSB67_10765	COG1028	Short-chain dehydrogenase reductase Sdr
DSB67_10770	COG1012	belongs to the aldehyde dehydrogenase family
DSB67_10770	COG1454	alcohol dehydrogenase
DSB67_10775	COG2095	MarC family integral membrane protein
DSB67_10780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSB67_10790	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DSB67_10795	COG1757	Na H antiporter
DSB67_10820	COG3083	sulfuric ester hydrolase activity
DSB67_10835	COG4269	membrane
DSB67_10845	COG0123	including yeast histone deacetylase and acetoin utilization protein
DSB67_10860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DSB67_10865	COG0778	Nitroreductase
DSB67_10870	COG1902	pentaerythritol trinitrate reductase activity
DSB67_10870	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSB67_10875	COG0616	signal peptide processing
DSB67_10880	COG0252	asparaginase activity
DSB67_10885	COG3139	Protein of unknown function (DUF1315)
DSB67_10895	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSB67_10900	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DSB67_10920	COG2226	methyltransferase
DSB67_10940	COG1785	Belongs to the alkaline phosphatase family
DSB67_10950	COG0346	lactoylglutathione lyase activity
DSB67_10960	COG0668	transmembrane transport
DSB67_10965	COG0076	glutamate decarboxylase activity
DSB67_10970	COG2985	domain, Protein
DSB67_10975	COG2261	transglycosylase associated protein
DSB67_10980	COG2983	Belongs to the UPF0260 family
DSB67_10990	COG2964	Protein conserved in bacteria
DSB67_11000	COG0251	oxidation-reduction process
DSB67_11005	COG0814	amino acid
DSB67_11010	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DSB67_11015	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DSB67_11025	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DSB67_11035	COG2832	Protein of unknown function (DUF454)
DSB67_11045	COG0745	RESPONSE REGULATOR receiver
DSB67_11050	COG0583	DNA-binding transcription factor activity
DSB67_11055	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DSB67_11060	COG1286	toxin biosynthetic process
DSB67_11065	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
DSB67_11070	COG0285	dihydrofolate synthase activity
DSB67_11095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DSB67_11100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DSB67_11110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DSB67_11130	COG3101	peptidyl-lysine hydroxylation
DSB67_11135	COG2860	membrane
DSB67_11150	COG2890	protein-(glutamine-N5) methyltransferase activity
DSB67_11160	COG2062	phosphohistidine phosphatase, SixA
DSB67_11175	COG0183	Belongs to the thiolase family
DSB67_11195	COG2067	long-chain fatty acid transport protein
DSB67_11200	COG2067	long-chain fatty acid transport protein
DSB67_11205	COG2853	Lipoprotein
DSB67_11210	COG4235	cytochrome complex assembly
DSB67_11210	COG3088	subunit of a heme lyase
DSB67_11220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSB67_11225	COG1138	Cytochrome C-type biogenesis protein
DSB67_11240	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DSB67_11245	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DSB67_11250	COG4133	protoheme IX ABC transporter activity
DSB67_11260	COG0835	chemotaxis
DSB67_11270	COG1192	Involved in chromosome partitioning
DSB67_11275	COG2201	protein-glutamate methylesterase activity
DSB67_11280	COG2198	Histidine kinase
DSB67_11280	COG0643	Histidine kinase
DSB67_11285	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DSB67_11300	COG0455	bacterial-type flagellum organization
DSB67_11320	COG1684	flagellar biosynthetic protein fliR
DSB67_11325	COG1987	bacterial-type flagellum assembly
DSB67_11380	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DSB67_11390	COG1677	Flagellar hook-basal body complex protein FliE
DSB67_11395	COG2204	response regulator
DSB67_11400	COG4191	Histidine kinase
DSB67_11410	COG1516	flagellar protein fliS
DSB67_11420	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DSB67_11425	COG1334	flagellar protein FlaG
DSB67_11430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DSB67_11435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DSB67_11445	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DSB67_11450	COG2837	iron assimilation
DSB67_11475	COG1393	Belongs to the ArsC family
DSB67_11500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DSB67_11505	COG2716	regulation of RNA biosynthetic process
DSB67_11510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSB67_11525	COG4783	chaperone-mediated protein folding
DSB67_11530	COG1393	Belongs to the ArsC family
DSB67_11550	COG2233	PERMEase
DSB67_11555	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DSB67_11560	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DSB67_11565	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DSB67_11570	COG0121	glutamine amidotransferase
DSB67_11575	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DSB67_11580	COG1960	acyl-CoA dehydrogenase activity
DSB67_11605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DSB67_11615	COG2226	methyltransferase
DSB67_11625	COG1388	LysM domain
DSB67_11625	COG0741	lytic transglycosylase activity
DSB67_11640	COG0347	Belongs to the P(II) protein family
DSB67_11660	COG0587	DNA-directed DNA polymerase activity
DSB67_11685	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSB67_11690	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
DSB67_11700	COG0750	zinc metalloprotease
DSB67_11710	COG0575	Belongs to the CDS family
DSB67_11715	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DSB67_11740	COG0024	Methionine aminopeptidase
DSB67_11755	COG0564	pseudouridine synthase activity
DSB67_11760	COG3098	single-species biofilm formation
DSB67_11795	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DSB67_11810	COG1720	tRNA m6t6A37 methyltransferase activity
DSB67_11835	COG0733	neurotransmitter:sodium symporter activity
DSB67_11850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DSB67_11855	COG0514	ATP-dependent DNA helicase (RecQ)
DSB67_11860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DSB67_11865	COG0745	RESPONSE REGULATOR receiver
DSB67_11865	COG3706	GGDEF domain
DSB67_11875	COG1477	protein flavinylation
DSB67_11900	COG1805	sodium ion transport
DSB67_11905	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DSB67_11910	COG0271	Belongs to the BolA IbaG family
DSB67_11940	COG1595	DNA-templated transcription, initiation
DSB67_11965	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DSB67_11970	COG0693	protein deglycase activity
DSB67_11975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DSB67_11980	COG2166	iron-sulfur cluster assembly
DSB67_11985	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DSB67_11990	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DSB67_12005	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DSB67_12005	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DSB67_12015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DSB67_12020	COG1074	ATP-dependent DNA helicase activity
DSB67_12025	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DSB67_12030	COG3083	sulfuric ester hydrolase activity
DSB67_12050	COG3141	response to X-ray
DSB67_12070	COG2171	N-acyltransferase activity
DSB67_12075	COG0584	glycerophosphoryl diester phosphodiesterase
DSB67_12080	COG2271	Major facilitator Superfamily
DSB67_12090	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DSB67_12100	COG1349	DNA-binding transcription factor activity
DSB67_12105	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DSB67_12125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSB67_12130	COG0768	penicillin binding
DSB67_12135	COG1609	Transcriptional regulator
DSB67_12140	COG0583	DNA-binding transcription factor activity
DSB67_12150	COG1022	Amp-dependent synthetase and ligase
DSB67_12180	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DSB67_12185	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DSB67_12195	COG0560	Phosphoserine phosphatase
DSB67_12205	COG0813	purine-nucleoside phosphorylase activity
DSB67_12215	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DSB67_12225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DSB67_12230	COG0084	hydrolase, TatD family'
DSB67_12255	COG3153	acetyltransferase
DSB67_12280	COG0534	Mate efflux family protein
DSB67_12300	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DSB67_12320	COG0195	Participates in both transcription termination and antitermination
DSB67_12340	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DSB67_12355	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DSB67_12360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSB67_12370	COG1534	Rna-binding protein
DSB67_12375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DSB67_12380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DSB67_12385	COG2027	D-alanyl-D-alanine carboxypeptidase
DSB67_12400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DSB67_12405	COG0739	heme binding
DSB67_12410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSB67_12430	COG0628	permease
DSB67_12445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSB67_12445	COG2205	protein histidine kinase activity
DSB67_12445	COG2198	Histidine kinase
DSB67_12445	COG0784	Response regulator, receiver
DSB67_12450	COG0747	negative chemotaxis
DSB67_12460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSB67_12465	COG0444	Belongs to the ABC transporter superfamily
DSB67_12470	COG4608	Belongs to the ABC transporter superfamily
DSB67_12480	COG2971	BadF BadG BcrA BcrD
DSB67_12495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DSB67_12500	COG3842	ATPase activity
DSB67_12510	COG1840	ABC-type Fe3 transport system, periplasmic component
DSB67_12515	COG0004	ammonium transporteR
DSB67_12530	COG1049	propionate catabolic process, 2-methylcitrate cycle
DSB67_12535	COG1752	Esterase of the alpha-beta hydrolase superfamily
DSB67_12540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DSB67_12545	COG1643	Atp-dependent helicase
DSB67_12555	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DSB67_12560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSB67_12575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DSB67_12590	COG1560	Kdo2-lipid A biosynthetic process
DSB67_12595	COG0842	Transport permease protein
DSB67_12600	COG1131	(ABC) transporter
DSB67_12605	COG0659	secondary active sulfate transmembrane transporter activity
DSB67_12610	COG0288	reversible hydration of carbon dioxide
DSB67_12630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSB67_12635	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSB67_12640	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DSB67_12645	COG2186	Transcriptional regulator
DSB67_12665	COG4969	Belongs to the N-Me-Phe pilin family
DSB67_12670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSB67_12675	COG1459	type II secretion system
DSB67_12685	COG0237	dephospho-CoA kinase activity
DSB67_12690	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
DSB67_12695	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DSB67_12720	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DSB67_12725	COG4137	Cytochrome C assembly protein
DSB67_12730	COG4536	flavin adenine dinucleotide binding
DSB67_12750	COG0612	Peptidase, M16
DSB67_12755	COG1238	metal cluster binding
DSB67_12765	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DSB67_12770	COG5016	pyruvate
DSB67_12770	COG0511	ligase activity, forming carbon-carbon bonds
DSB67_12865	COG0527	aspartate kinase activity
DSB67_12880	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DSB67_12885	COG1546	Belongs to the CinA family
DSB67_12895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DSB67_12925	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DSB67_12935	COG0148	phosphopyruvate hydratase activity
DSB67_12945	COG3956	TIGRFAM MazG family protein
DSB67_12950	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DSB67_12975	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DSB67_12980	COG1381	Involved in DNA repair and RecF pathway recombination
DSB67_12985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DSB67_12995	COG0681	Belongs to the peptidase S26 family
DSB67_13005	COG3086	response to oxidative stress
DSB67_13020	COG1595	DNA-templated transcription, initiation
DSB67_13025	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DSB67_13035	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DSB67_13055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DSB67_13060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DSB67_13075	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DSB67_13085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DSB67_13095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DSB67_13105	COG0583	DNA-binding transcription factor activity
DSB67_13120	COG0668	transmembrane transport
DSB67_13125	COG0191	fructose-bisphosphate aldolase activity
DSB67_13145	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DSB67_13165	COG2356	endonuclease I
DSB67_13170	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DSB67_13175	COG0189	ligase activity
DSB67_13180	COG1678	Uncharacterized ACR, COG1678
DSB67_13185	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DSB67_13200	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DSB67_13205	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DSB67_13210	COG0762	integral membrane protein
DSB67_13225	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DSB67_13230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DSB67_13330	COG1012	belongs to the aldehyde dehydrogenase family
DSB67_13395	COG1486	melibiose metabolic process
DSB67_13400	COG1447	Phosphotransferase system cellobiose-specific component IIA
DSB67_13415	COG0726	polysaccharide deacetylase
DSB67_13425	COG1028	Short-chain dehydrogenase reductase Sdr
DSB67_13435	COG0795	lipopolysaccharide-transporting ATPase activity
DSB67_13440	COG0795	lipopolysaccharide-transporting ATPase activity
DSB67_13450	COG2927	DNA polymerase III (CHI subunit)
DSB67_13455	COG0525	valine-tRNA ligase activity
DSB67_13505	COG0251	oxidation-reduction process
DSB67_13510	COG0204	Acyl-transferase
DSB67_13520	COG5007	Belongs to the BolA IbaG family
DSB67_13530	COG2854	intermembrane phospholipid transfer
DSB67_13535	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DSB67_13540	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DSB67_13545	COG1127	ABC transporter
DSB67_13555	COG0517	IMP dehydrogenase activity
DSB67_13555	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DSB67_13565	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DSB67_13570	COG1137	ATPase activity
DSB67_13580	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DSB67_13585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSB67_13595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSB67_13600	COG2239	Acts as a magnesium transporter
DSB67_13605	COG0312	modulator of DNA gyrase
DSB67_13615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DSB67_13620	COG0564	pseudouridine synthase activity
DSB67_13635	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DSB67_13640	COG0312	modulator of DNA gyrase
DSB67_13645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DSB67_13650	COG3164	Protein of unknown function
DSB67_13655	COG1530	ribonuclease E activity
DSB67_13660	COG0424	maF-like protein
DSB67_13665	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DSB67_13670	COG1792	Involved in formation and maintenance of cell shape
DSB67_13675	COG1077	Cell shape determining protein MreB Mrl
DSB67_13720	COG1459	type II secretion system
DSB67_13725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSB67_13735	COG3409	Peptidoglycan-binding domain 1 protein
DSB67_13735	COG3267	Type II secretory pathway component ExeA
DSB67_13760	COG2200	EAL domain
DSB67_13760	COG2199	diguanylate cyclase activity
DSB67_13765	COG0629	single-stranded DNA binding
DSB67_13780	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DSB67_13790	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DSB67_13800	COG0527	aspartate kinase activity
DSB67_13805	COG0646	methionine synthase
DSB67_13805	COG1410	methionine synthase
DSB67_13875	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DSB67_13895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DSB67_13900	COG0735	belongs to the Fur family
DSB67_13915	COG0432	Pfam Uncharacterised protein family UPF0047
DSB67_13925	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DSB67_13930	COG0305	Participates in initiation and elongation during chromosome replication
DSB67_13950	COG2965	DNA replication, synthesis of RNA primer
DSB67_13960	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DSB67_13965	COG0338	D12 class N6 adenine-specific DNA methyltransferase
DSB67_14010	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DSB67_14020	COG0678	peroxiredoxin activity
DSB67_14020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DSB67_14025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSB67_14040	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DSB67_14040	COG0165	Argininosuccinate lyase
DSB67_14055	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DSB67_14065	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DSB67_14075	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DSB67_14080	COG0460	homoserine dehydrogenase
DSB67_14080	COG0527	aspartate kinase activity
DSB67_14085	COG0626	cystathionine gamma-synthase activity
DSB67_14095	COG0281	malic enzyme
DSB67_14105	COG2906	2 iron, 2 sulfur cluster binding
DSB67_14115	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DSB67_14130	COG2168	tRNA wobble position uridine thiolation
DSB67_14135	COG2923	Belongs to the DsrF TusC family
DSB67_14140	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DSB67_14145	COG2964	Protein conserved in bacteria
DSB67_14150	COG0545	Peptidyl-prolyl cis-trans isomerase
DSB67_14165	COG1446	asparaginase
DSB67_14175	COG1047	Peptidyl-prolyl cis-trans
DSB67_14190	COG2249	NAD(P)H dehydrogenase (quinone) activity
DSB67_14200	COG0488	(ABC) transporter
DSB67_14210	COG0429	hydrolase of the alpha beta-hydrolase fold
DSB67_14220	COG3954	Phosphoribulokinase
DSB67_14225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSB67_14245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DSB67_14250	COG0512	Glutamine amidotransferase of anthranilate synthase
DSB67_14265	COG0546	phosphoglycolate phosphatase activity
DSB67_14270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DSB67_14275	COG0557	exoribonuclease II activity
DSB67_14285	COG1017	nitric oxide dioxygenase activity
DSB67_14285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DSB67_14290	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
DSB67_14300	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DSB67_14305	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
DSB67_14310	COG0330	HflC and HflK could
DSB67_14315	COG0330	HflC and HflK could
DSB67_14320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DSB67_14335	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DSB67_14340	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSB67_14345	COG0802	atpase or kinase
DSB67_14350	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DSB67_14430	COG1162	GTPase activity
DSB67_14440	COG0471	metal ion transport
DSB67_14455	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DSB67_14460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DSB67_14475	COG1045	serine acetyltransferase
DSB67_14480	COG4942	peptidase
DSB67_14505	COG1053	succinate dehydrogenase
DSB67_14510	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DSB67_14540	COG1509	lysine 2,3-aminomutase activity
DSB67_14565	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DSB67_14570	COG0534	Mate efflux family protein
DSB67_14580	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DSB67_14590	COG0745	RESPONSE REGULATOR receiver
DSB67_14595	COG2205	protein histidine kinase activity
DSB67_14605	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DSB67_14610	COG3030	protein affecting phage T7 exclusion by the F plasmid
DSB67_14615	COG1027	Aspartate ammonia-lyase
DSB67_14620	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DSB67_14625	COG4232	protein-disulfide reductase activity
DSB67_14635	COG2095	MarC family integral membrane protein
DSB67_14645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DSB67_14665	COG0784	Response regulator, receiver
DSB67_14665	COG2198	Histidine kinase
DSB67_14665	COG2205	protein histidine kinase activity
DSB67_14670	COG2814	Major facilitator Superfamily
DSB67_14685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSB67_14690	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DSB67_14695	COG0511	ligase activity, forming carbon-carbon bonds
DSB67_14700	COG0439	Biotin carboxylase
DSB67_14715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DSB67_14720	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DSB67_14725	COG5001	Diguanylate cyclase
DSB67_14725	COG3300	MHYT domain
DSB67_14775	COG1982	Orn Lys Arg decarboxylase major
DSB67_14780	COG0531	amino acid
DSB67_14790	COG3710	Transcriptional regulator
DSB67_14795	COG0789	Transcriptional regulator
DSB67_14805	COG0151	Belongs to the GarS family
DSB67_14820	COG1253	flavin adenine dinucleotide binding
DSB67_14825	COG3068	Protein conserved in bacteria
DSB67_14835	COG1573	uracil-dna glycosylase
DSB67_14855	COG2816	NAD+ diphosphatase activity
DSB67_14860	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
DSB67_14880	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DSB67_14895	COG0250	Participates in transcription elongation, termination and antitermination
DSB67_14900	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DSB67_14945	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DSB67_14955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DSB67_15055	COG0534	Mate efflux family protein
DSB67_15075	COG2937	Belongs to the GPAT DAPAT family
DSB67_15085	COG3161	chorismate lyase activity
DSB67_15090	COG1580	Controls the rotational direction of flagella during chemotaxis
DSB67_15095	COG0705	Rhomboid family
DSB67_15115	COG2177	Part of the ABC transporter FtsEX involved in
DSB67_15120	COG2884	Cell division ATP-binding protein ftsE
DSB67_15125	COG0552	protein localization to endoplasmic reticulum
DSB67_15130	COG0742	ribosomal rna small subunit methyltransferase
DSB67_15140	COG2095	MarC family integral membrane protein
DSB67_15195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DSB67_15200	COG0640	Transcriptional regulator
DSB67_15205	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DSB67_15210	COG1280	lysine exporter protein (LysE YggA)
DSB67_15215	COG2267	carboxylic ester hydrolase activity
DSB67_15220	COG0561	phosphatase activity
DSB67_15240	COG2199	diguanylate cyclase activity
DSB67_15240	COG3287	FIST C domain
DSB67_15240	COG2200	EAL domain
DSB67_15245	COG1011	Hydrolase
DSB67_15265	COG0019	diaminopimelate decarboxylase activity
DSB67_15280	COG3072	Adenylate cyclase
DSB67_15290	COG1587	Uroporphyrinogen-III synthase
DSB67_15295	COG2959	enzyme of heme biosynthesis
DSB67_15300	COG3071	HemY protein
DSB67_15350	COG0633	Ferredoxin
DSB67_15355	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DSB67_15365	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DSB67_15370	COG3118	belongs to the thioredoxin family
DSB67_15385	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DSB67_15400	COG0514	ATP-dependent DNA helicase (RecQ)
DSB67_15405	COG2962	Rard protein
DSB67_15415	COG1280	lysine exporter protein (LysE YggA)
DSB67_15420	COG0405	Gamma-glutamyltransferase
DSB67_15430	COG0210	DNA helicase
DSB67_15440	COG3220	belongs to the UPF0276 family
DSB67_15460	COG2814	Major facilitator Superfamily
DSB67_15470	COG0006	proline dipeptidase activity
DSB67_15470	COG0006	proline dipeptidase activity
DSB67_15485	COG2104	thiamine diphosphate biosynthetic process
DSB67_15490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DSB67_15510	COG2132	Multicopper oxidase
DSB67_15560	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DSB67_15585	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DSB67_15590	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DSB67_15595	COG0551	DNA topoisomerase type I activity
DSB67_15605	COG0758	DNA mediated transformation
DSB67_15615	COG0242	peptide deformylase activity
DSB67_15625	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DSB67_15625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DSB67_15630	COG0569	domain protein
DSB67_15635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DSB67_15645	COG1272	protein, Hemolysin III
DSB67_15650	COG4326	sporulation control protein
DSB67_15660	COG3084	Protein conserved in bacteria
DSB67_15670	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DSB67_15675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DSB67_15680	COG0204	Acyl-transferase
DSB67_15690	COG2199	diguanylate cyclase activity
DSB67_15695	COG0606	chelatase, subunit chli
DSB67_15705	COG3978	acetolactate synthase activity
DSB67_15710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DSB67_15715	COG0129	dihydroxy-acid dehydratase activity
DSB67_15725	COG0583	DNA-binding transcription factor activity
DSB67_15730	COG2814	Major facilitator Superfamily
DSB67_15735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSB67_15740	COG0765	amino acid transport
DSB67_15750	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DSB67_15760	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DSB67_15790	COG3312	ion transport
DSB67_15795	COG1475	DNA binding
DSB67_15800	COG1192	Involved in chromosome partitioning
DSB67_15815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DSB67_15830	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DSB67_15845	COG1126	abc transporter atp-binding protein
DSB67_15940	COG0739	heme binding
DSB67_15955	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DSB67_15985	COG3069	C4-dicarboxylate transmembrane transporter activity
DSB67_16015	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DSB67_16025	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DSB67_16085	COG0784	Response regulator, receiver
DSB67_16085	COG2198	Histidine kinase
DSB67_16085	COG2205	protein histidine kinase activity
DSB67_16090	COG1879	ABC-type sugar transport system periplasmic component
DSB67_16100	COG0210	DNA helicase
DSB67_16105	COG1289	transmembrane transporter activity
DSB67_16130	COG0789	Transcriptional regulator
DSB67_16135	COG4604	ABC transporter, ATP-binding protein
DSB67_16140	COG4605	iron ion homeostasis
DSB67_16145	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DSB67_16150	COG4607	ABC-type enterochelin transport system periplasmic component
DSB67_16165	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
DSB67_16180	COG1609	Transcriptional regulator
DSB67_16185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DSB67_16190	COG1879	ABC-type sugar transport system periplasmic component
DSB67_16195	COG1172	Belongs to the binding-protein-dependent transport system permease family
DSB67_16200	COG1129	ABC transporter
DSB67_16210	COG5001	Diguanylate cyclase
DSB67_16275	COG0784	Response regulator, receiver
DSB67_16275	COG2205	protein histidine kinase activity
DSB67_16300	COG0330	HflC and HflK could
DSB67_16315	COG4175	Glycine betaine
DSB67_16315	COG0517	IMP dehydrogenase activity
DSB67_16355	COG2885	chlorophyll binding
DSB67_16395	COG0455	bacterial-type flagellum organization
DSB67_16405	COG4964	Belongs to the GSP D family
DSB67_16425	COG0583	DNA-binding transcription factor activity
DSB67_16460	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DSB67_16460	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DSB67_16475	COG4989	oxidoreductase activity
DSB67_16505	COG0303	'Molybdopterin
DSB67_16510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DSB67_16545	COG2897	thiosulfate sulfurtransferase activity
DSB67_16570	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DSB67_16575	COG0840	transmembrane signaling receptor activity
DSB67_16585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DSB67_16600	COG1612	heme a metabolic process
DSB67_16625	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DSB67_16640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DSB67_16650	COG1280	lysine exporter protein (LysE YggA)
DSB67_16670	COG0179	Fumarylacetoacetate (FAA) hydrolase
DSB67_16685	COG0697	spore germination
DSB67_16705	COG2814	Major facilitator Superfamily
DSB67_16710	COG0583	DNA-binding transcription factor activity
DSB67_16740	COG1120	ATPase activity
DSB67_16745	COG5001	Diguanylate cyclase
DSB67_16750	COG0739	heme binding
DSB67_16790	COG0814	amino acid
DSB67_16825	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DSB67_16830	COG1120	ATPase activity
DSB67_16855	COG0798	PFAM Bile acid sodium symporter
DSB67_16870	COG1881	PFAM PEBP family protein
DSB67_16885	COG2706	6-phosphogluconolactonase activity
DSB67_16895	COG0800	Aldolase
DSB67_16915	COG1131	(ABC) transporter
DSB67_16920	COG0842	Transport permease protein
DSB67_16955	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSB67_16965	COG1280	lysine exporter protein (LysE YggA)
DSB67_16970	COG0583	DNA-binding transcription factor activity
DSB67_16985	COG0494	nUDIX hydrolase
DSB67_17000	COG1858	cytochrome C peroxidase
DSB67_17030	COG1505	serine-type exopeptidase activity
DSB67_17045	COG0589	response to stress
DSB67_17055	COG0584	glycerophosphoryl diester phosphodiesterase
DSB67_17065	COG1175	transmembrane transport
DSB67_17070	COG0395	ABC-type sugar transport system, permease component
DSB67_17075	COG3842	ATPase activity
DSB67_17090	COG1846	Transcriptional regulator
DSB67_17100	COG0523	cobalamin synthesis protein
DSB67_17110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DSB67_17120	COG4667	esterase of the alpha-beta hydrolase superfamily
DSB67_17125	COG1741	Belongs to the pirin family
DSB67_17130	COG1278	Cold shock
DSB67_17145	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DSB67_17155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DSB67_17165	COG1686	Belongs to the peptidase S11 family
DSB67_17170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DSB67_17175	COG0625	glutathione transferase activity
DSB67_17245	COG1764	response to oxidative stress
DSB67_17250	COG2084	Dehydrogenase
DSB67_17255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSB67_17260	COG0823	Involved in the tonB-independent uptake of proteins
DSB67_17275	COG1028	Short-chain dehydrogenase reductase Sdr
DSB67_17280	COG3483	tryptophan 2,3-dioxygenase activity
DSB67_17315	COG0583	DNA-binding transcription factor activity
DSB67_17330	COG0494	nUDIX hydrolase
DSB67_17430	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DSB67_17430	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DSB67_17450	COG1028	Short-chain dehydrogenase reductase Sdr
DSB67_17475	COG3746	phosphate-selective porin O and P
DSB67_17495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSB67_17535	COG0513	Belongs to the DEAD box helicase family
DSB67_17540	COG0583	DNA-binding transcription factor activity
DSB67_17565	COG1902	pentaerythritol trinitrate reductase activity
DSB67_17570	COG3853	Toxic anion resistance protein (TelA)
DSB67_17595	COG3122	Protein conserved in bacteria
DSB67_17600	COG2321	neutral zinc metallopeptidase
DSB67_17610	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DSB67_17615	COG1215	transferase activity, transferring glycosyl groups
DSB67_17625	COG0583	DNA-binding transcription factor activity
DSB67_17640	COG2207	Transcriptional regulator
DSB67_17645	COG2807	transmembrane transport
DSB67_17655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DSB67_17655	COG0574	Belongs to the PEP-utilizing enzyme family
DSB67_17675	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DSB67_17680	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DSB67_17715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DSB67_17735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSB67_17750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSB67_17800	COG4948	Mandelate Racemase Muconate Lactonizing
DSB67_17840	COG4176	ABC-type proline glycine betaine transport system permease component
DSB67_17845	COG4175	Glycine betaine
DSB67_17845	COG3448	diguanylate cyclase activity
DSB67_17860	COG0583	DNA-binding transcription factor activity
DSB67_17870	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DSB67_17905	COG1335	isochorismatase
DSB67_17920	COG1349	DNA-binding transcription factor activity
DSB67_17925	COG0346	lactoylglutathione lyase activity
DSB67_17930	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSB67_17930	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSB67_17940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSB67_17960	COG1280	lysine exporter protein (LysE YggA)
DSB67_17965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DSB67_17980	COG0488	(ABC) transporter
DSB67_17985	COG0435	Glutathione S-transferase
DSB67_17990	COG0431	NADPH-dependent FMN reductase
DSB67_17995	COG0583	DNA-binding transcription factor activity
DSB67_18005	COG4628	conserved protein (DUF2132)
DSB67_18010	COG0488	(ABC) transporter
DSB67_18025	COG0346	lactoylglutathione lyase activity
DSB67_18030	COG0384	phenazine biosynthesis protein PhzF
DSB67_18050	COG2205	protein histidine kinase activity
DSB67_18055	COG0745	RESPONSE REGULATOR receiver
DSB67_18065	COG0454	-acetyltransferase
DSB67_18075	COG2814	Major facilitator Superfamily
DSB67_18085	COG2988	succinylglutamate desuccinylase activity
DSB67_18095	COG0628	permease
DSB67_18100	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
DSB67_18115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DSB67_18125	COG4628	conserved protein (DUF2132)
DSB67_18130	COG0583	DNA-binding transcription factor activity
DSB67_18140	COG1686	Belongs to the peptidase S11 family
DSB67_18155	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DSB67_18180	COG0415	Belongs to the DNA photolyase family
DSB67_18185	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DSB67_18195	COG4667	esterase of the alpha-beta hydrolase superfamily
DSB67_18210	COG1596	polysaccharide export
DSB67_18240	COG1301	dicarboxylic acid transport
DSB67_18245	COG3339	Conserved Protein
DSB67_18260	COG2207	Transcriptional regulator
DSB67_18275	COG0366	Alpha amylase catalytic
DSB67_18280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DSB67_18285	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DSB67_18290	COG1640	4-alpha-glucanotransferase
DSB67_18295	COG0058	SHG alpha-glucan phosphorylase activity
DSB67_18320	COG1999	signal sequence binding
DSB67_18330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSB67_18330	COG1263	PTS System
DSB67_18335	COG1162	GTPase activity
DSB67_18340	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DSB67_18360	COG0531	amino acid
DSB67_18365	COG1982	Orn Lys Arg decarboxylase major
DSB67_18385	COG2356	endonuclease I
DSB67_18405	COG4580	involved in the transport of maltose and maltodextrins
DSB67_18425	COG2814	Major facilitator Superfamily
DSB67_18435	COG0739	heme binding
DSB67_18470	COG3121	Chaperone
DSB67_18475	COG3188	usher protein
DSB67_18505	COG0612	Peptidase, M16
DSB67_18510	COG0840	transmembrane signaling receptor activity
DSB67_18530	COG1335	isochorismatase
DSB67_18535	COG1136	(ABC) transporter
DSB67_18575	COG1764	response to oxidative stress
DSB67_18580	COG1846	Transcriptional regulator
DSB67_18585	COG0450	alkyl hydroperoxide reductase
DSB67_18590	COG3634	alkyl hydroperoxide reductase activity
DSB67_18605	COG2610	gluconate transmembrane transporter activity
DSB67_18610	COG3622	Belongs to the hyi family
DSB67_18615	COG0235	Class ii aldolase
DSB67_18620	COG3395	kinase activity
DSB67_18625	COG2084	Dehydrogenase
DSB67_18630	COG1349	DNA-binding transcription factor activity
DSB67_18670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DSB67_18680	COG3766	membrane
DSB67_18690	COG0754	glutathionylspermidine amidase activity
DSB67_18695	COG3831	ATPase activity
DSB67_18700	COG0714	Associated with various cellular activities
DSB67_18705	COG2425	protein containing a von Willebrand factor type A (vWA) domain
DSB67_18710	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DSB67_18735	COG1522	sequence-specific DNA binding
DSB67_18740	COG0544	peptidyl-prolyl cis-trans isomerase activity
DSB67_18745	COG0544	peptidyl-prolyl cis-trans isomerase activity
DSB67_18750	COG0544	peptidyl-prolyl cis-trans isomerase activity
DSB67_18765	COG2258	MOSC domain
DSB67_18770	COG2153	protein acetylation
DSB67_18780	COG0513	Belongs to the DEAD box helicase family
DSB67_18785	COG0667	Aldo Keto reductase
DSB67_18800	COG1132	(ABC) transporter
DSB67_18945	COG4166	transmembrane transport
DSB67_18975	COG1444	tRNA N-acetyltransferase activity
DSB67_19000	COG4608	Belongs to the ABC transporter superfamily
DSB67_19005	COG0444	Belongs to the ABC transporter superfamily
DSB67_19015	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
DSB67_19015	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DSB67_19055	COG1136	(ABC) transporter
DSB67_19075	COG3275	phosphorelay sensor kinase activity
DSB67_19080	COG3279	Response regulator of the LytR AlgR family
DSB67_19090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DSB67_19110	COG0786	glutamate:sodium symporter activity
DSB67_19115	COG1028	Short-chain dehydrogenase reductase Sdr
DSB67_19165	COG0583	DNA-binding transcription factor activity
DSB67_19180	COG2897	thiosulfate sulfurtransferase activity
DSB67_19190	COG1131	(ABC) transporter
DSB67_19195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSB67_19235	COG0561	phosphatase activity
DSB67_19240	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
DSB67_19245	COG3623	hexulose-6-phosphate isomerase
DSB67_19280	COG2259	Doxx family
DSB67_19290	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DSB67_19295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DSB67_19415	COG4974	Belongs to the 'phage' integrase family
DSB67_19470	COG4580	involved in the transport of maltose and maltodextrins
DSB67_19475	COG1609	Transcriptional regulator
DSB67_19490	COG0395	ABC-type sugar transport system, permease component
DSB67_19495	COG2723	6-phospho-beta-galactosidase activity
DSB67_19500	COG3842	ATPase activity
DSB67_19505	COG1609	Transcriptional regulator
DSB67_19515	COG0564	pseudouridine synthase activity
DSB67_19520	COG0561	phosphatase activity
DSB67_19530	COG2199	diguanylate cyclase activity
DSB67_19540	COG3152	Membrane
DSB67_19555	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DSB67_19570	COG0583	DNA-binding transcription factor activity
DSB67_19620	COG2076	Multidrug Resistance protein
DSB67_19630	COG1357	PFAM Pentapeptide repeats (8 copies)
DSB67_19635	COG3047	cAMP biosynthetic process
DSB67_19730	COG0668	transmembrane transport
DSB67_19775	COG3835	regulator
DSB67_19780	COG1929	Belongs to the glycerate kinase type-1 family
DSB67_19800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSB67_19850	COG1028	Short-chain dehydrogenase reductase Sdr
DSB67_19865	COG0671	phosphoesterase, PA-phosphatase related
DSB67_19880	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DSB67_19885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DSB67_19890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSB67_19895	COG1116	anion transmembrane transporter activity
DSB67_19900	COG0351	phosphomethylpyrimidine kinase
DSB67_19905	COG0312	modulator of DNA gyrase
DSB67_19910	COG0312	modulator of DNA gyrase
DSB67_19915	COG1901	pseudouridine methyltransferase
DSB67_19975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DSB67_19985	COG0584	glycerophosphoryl diester phosphodiesterase
DSB67_19990	COG0745	RESPONSE REGULATOR receiver
DSB67_20010	COG0811	peptide transport
DSB67_20015	COG0811	peptide transport
DSB67_20020	COG0848	biopolymer transport protein
DSB67_20065	COG0803	Belongs to the bacterial solute-binding protein 9 family
DSB67_20070	COG1121	(ABC) transporter
DSB67_20075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DSB67_20090	COG1770	oligopeptidase
DSB67_20095	COG2814	Major facilitator Superfamily
DSB67_20100	COG0010	Belongs to the arginase family
DSB67_20105	COG1166	arginine decarboxylase activity
DSB67_20115	COG0189	ligase activity
DSB67_20115	COG4067	protein conserved in archaea
DSB67_20120	COG0189	ligase activity
DSB67_20145	COG0583	DNA-binding transcription factor activity
DSB67_20170	COG2723	6-phospho-beta-galactosidase activity
DSB67_20185	COG1114	Component of the transport system for branched-chain amino acids
DSB67_20205	COG0579	oxidoreductase
DSB67_20225	COG3033	Beta-eliminating lyase
DSB67_20245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DSB67_20250	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DSB67_20285	COG3706	GGDEF domain
DSB67_20290	COG0415	Belongs to the DNA photolyase family
DSB67_20295	COG3046	protein related to deoxyribodipyrimidine photolyase
DSB67_20310	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSB67_20310	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSB67_20315	COG1765	OsmC-like protein
DSB67_20370	COG1011	Hydrolase
DSB67_20395	COG3240	lipase activity
DSB67_20425	COG1840	ABC-type Fe3 transport system, periplasmic component
DSB67_20435	COG3842	ATPase activity
DSB67_20460	COG2990	Protein conserved in bacteria
DSB67_20470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DSB67_20475	COG2866	Carboxypeptidase
DSB67_20485	COG0583	DNA-binding transcription factor activity
DSB67_20515	COG1760	l-serine dehydratase
DSB67_20540	COG0741	lytic transglycosylase activity
DSB67_20540	COG1388	LysM domain
DSB67_20560	COG1815	bacterial-type flagellum-dependent cell motility
DSB67_20565	COG1558	bacterial-type flagellum-dependent cell motility
DSB67_20570	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DSB67_20575	COG1749	Flagellar hook protein flgE
DSB67_20580	COG4787	bacterial-type flagellum-dependent cell motility
DSB67_20585	COG4786	Flagellar basal body rod
DSB67_20590	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DSB67_20595	COG1706	bacterial-type flagellum-dependent cell motility
DSB67_20605	COG4786	Flagellar basal body rod
DSB67_20605	COG1256	bacterial-type flagellum assembly
DSB67_20610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DSB67_20670	COG0384	phenazine biosynthesis protein PhzF
DSB67_20680	COG1360	Flagellar Motor Protein
DSB67_20685	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DSB67_20690	COG1191	sigma factor activity
DSB67_20695	COG1580	Controls the rotational direction of flagella during chemotaxis
DSB67_20715	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DSB67_20725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DSB67_20740	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DSB67_20750	COG1987	bacterial-type flagellum assembly
DSB67_20775	COG2204	response regulator
DSB67_20790	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DSB67_20850	COG0346	lactoylglutathione lyase activity
DSB67_20890	COG0156	8-amino-7-oxononanoate synthase activity
DSB67_20895	COG1063	alcohol dehydrogenase
DSB67_20900	COG4974	Belongs to the 'phage' integrase family
DSB67_21035	COG4695	Portal protein
DSB67_21170	COG1063	alcohol dehydrogenase
DSB67_21195	COG2199	diguanylate cyclase activity
DSB67_21195	COG2203	Gaf domain
DSB67_21200	COG2223	nitrite transmembrane transporter activity
DSB67_21205	COG1063	alcohol dehydrogenase
DSB67_21215	COG0668	transmembrane transport
DSB67_21230	COG1620	l-lactate permease
DSB67_21240	COG1505	serine-type exopeptidase activity
DSB67_21245	COG4172	Belongs to the ABC transporter superfamily
DSB67_21255	COG1067	ATP-dependent peptidase activity
DSB67_21265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DSB67_21285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSB67_21310	COG1122	ATPase activity
DSB67_21320	COG1566	PFAM secretion protein HlyD family protein
DSB67_21335	COG3706	GGDEF domain
DSB67_21350	COG0813	purine-nucleoside phosphorylase activity
DSB67_21360	COG3272	Protein of unknown function (DUF1722)
DSB67_21365	COG0789	Transcriptional regulator
DSB67_21370	COG0415	Belongs to the DNA photolyase family
DSB67_21375	COG1376	ErfK ybiS ycfS ynhG family protein
DSB67_21375	COG1388	LysM domain
DSB67_21410	COG0513	Belongs to the DEAD box helicase family
DSB67_21415	COG1770	oligopeptidase
DSB67_21420	COG4771	TonB-dependent receptor
DSB67_21445	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DSB67_21450	COG0573	inorganic phosphate transmembrane transporter activity
DSB67_21455	COG0581	inorganic phosphate transmembrane transporter activity
DSB67_21475	COG2304	oxidoreductase activity
DSB67_21495	COG0714	Associated with various cellular activities
DSB67_21505	COG0840	transmembrane signaling receptor activity
DSB67_21515	COG2197	response regulator
DSB67_21540	COG2204	response regulator
DSB67_21545	COG3852	Histidine kinase
DSB67_21570	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
DSB67_21575	COG0167	dihydroorotate dehydrogenase activity
DSB67_21595	COG1252	NADH dehydrogenase
DSB67_21600	COG1301	dicarboxylic acid transport
DSB67_21605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DSB67_21635	COG2084	Dehydrogenase
DSB67_21640	COG0753	catalase activity
DSB67_21650	COG2130	NADP-dependent
DSB67_21655	COG1309	transcriptional regulator
DSB67_21700	COG0489	protein tyrosine kinase activity
DSB67_21700	COG3206	protein involved in exopolysaccharide biosynthesis
DSB67_21715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DSB67_21720	COG3842	ATPase activity
DSB67_21735	COG1175	transmembrane transport
DSB67_21770	COG2354	Protein conserved in bacteria
DSB67_21780	COG0401	homolog of Blt101
DSB67_21785	COG3217	Mosc domain protein beta barrel domain protein
DSB67_21785	COG0633	Ferredoxin
DSB67_21785	COG0633	Ferredoxin
DSB67_21785	COG3217	Mosc domain protein beta barrel domain protein
DSB67_21835	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DSB67_21840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DSB67_21850	COG0848	biopolymer transport protein
DSB67_21855	COG0811	peptide transport
DSB67_21860	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
DSB67_21870	COG3721	Heme iron utilization protein
DSB67_21875	COG0748	coenzyme F420 binding
DSB67_21885	COG0835	chemotaxis
DSB67_21885	COG0784	Response regulator, receiver
DSB67_21890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSB67_21895	COG0366	Alpha amylase catalytic
DSB67_21930	COG0583	DNA-binding transcription factor activity
DSB67_21945	COG2249	NAD(P)H dehydrogenase (quinone) activity
DSB67_21965	COG4977	sequence-specific DNA binding
DSB67_21970	COG0673	inositol 2-dehydrogenase activity
DSB67_21975	COG2194	sulfuric ester hydrolase activity
DSB67_21980	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DSB67_21990	COG2205	protein histidine kinase activity
DSB67_21995	COG0745	RESPONSE REGULATOR receiver
DSB67_22000	COG4221	oxidoreductase activity
DSB67_22015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DSB67_22035	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DSB67_22045	COG2814	Major facilitator Superfamily
DSB67_22060	COG1418	mRNA catabolic process
DSB67_22075	COG0402	S-adenosylhomocysteine deaminase activity
DSB67_22080	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DSB67_22085	COG2239	Acts as a magnesium transporter
DSB67_22090	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DSB67_22095	COG1566	PFAM secretion protein HlyD family protein
DSB67_22120	COG0745	RESPONSE REGULATOR receiver
DSB67_22125	COG2205	protein histidine kinase activity
DSB67_22135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSB67_22140	COG0531	amino acid
DSB67_22155	COG0583	DNA-binding transcription factor activity
DSB67_22180	COG0673	inositol 2-dehydrogenase activity
DSB67_22185	COG0534	Mate efflux family protein
DSB67_22260	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DSB67_22265	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DSB67_22275	COG1280	lysine exporter protein (LysE YggA)
DSB67_22285	COG0183	Belongs to the thiolase family
DSB67_22305	COG3005	denitrification pathway
DSB67_22325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DSB67_22330	COG3850	Histidine kinase
DSB67_22335	COG2197	response regulator
DSB67_22350	COG2195	Cleaves the N-terminal amino acid of tripeptides
DSB67_22365	COG0840	transmembrane signaling receptor activity
DSB67_22375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DSB67_22380	COG0545	Peptidyl-prolyl cis-trans isomerase
DSB67_22410	COG1278	Cold shock
DSB67_22415	COG3036	rescue of stalled ribosome
DSB67_22425	COG2199	diguanylate cyclase activity
DSB67_22445	COG0577	efflux transmembrane transporter activity
DSB67_22445	COG1136	(ABC) transporter
DSB67_22455	COG0840	transmembrane signaling receptor activity
DSB67_22460	COG0783	Belongs to the Dps family
DSB67_22470	COG1619	proteins homologs of microcin C7 resistance protein MccF
DSB67_22475	COG2133	pyrroloquinoline quinone binding
DSB67_22480	COG1454	alcohol dehydrogenase
DSB67_22485	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
DSB67_22505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DSB67_22510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSB67_22520	COG3186	Phenylalanine-4-hydroxylase
DSB67_22550	COG3530	Putative quorum-sensing-regulated virulence factor
DSB67_22575	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DSB67_22580	COG1845	cytochrome c oxidase, subunit III
DSB67_22585	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DSB67_22590	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DSB67_22600	COG0454	-acetyltransferase
DSB67_22640	COG0523	cobalamin synthesis protein
DSB67_22645	COG5002	protein histidine kinase activity
DSB67_22645	COG5001	Diguanylate cyclase
DSB67_22645	COG3447	MASE1 domain protein
DSB67_22650	COG0513	Belongs to the DEAD box helicase family
DSB67_22670	COG2200	EAL domain
DSB67_22675	COG1119	ATPase activity
DSB67_22690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DSB67_22705	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
DSB67_22710	COG0513	Belongs to the DEAD box helicase family
DSB67_22725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DSB67_22740	COG3278	Belongs to the heme-copper respiratory oxidase family
DSB67_22780	COG1024	Enoyl-CoA hydratase
DSB67_22785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DSB67_22790	COG1960	acyl-CoA dehydrogenase activity
DSB67_22800	COG0183	Belongs to the thiolase family
DSB67_22815	COG1024	Enoyl-CoA hydratase
DSB67_22820	COG1024	Enoyl-CoA hydratase
DSB67_22830	COG1028	Short-chain dehydrogenase reductase Sdr
DSB67_22835	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DSB67_22840	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DSB67_22845	COG1845	cytochrome c oxidase, subunit III
DSB67_22850	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DSB67_22860	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSB67_22860	COG1902	pentaerythritol trinitrate reductase activity
DSB67_22875	COG1012	belongs to the aldehyde dehydrogenase family
DSB67_22885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DSB67_22920	COG1126	abc transporter atp-binding protein
DSB67_22925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSB67_22930	COG4215	(ABC) transporter
DSB67_22935	COG4160	amino acid transport
DSB67_22965	COG0745	RESPONSE REGULATOR receiver
DSB67_22970	COG5002	protein histidine kinase activity
DSB67_22970	COG5000	phosphorelay sensor kinase activity
DSB67_22975	COG2200	EAL domain
DSB67_23020	COG0443	Heat shock 70 kDa protein
DSB67_23050	COG1785	Belongs to the alkaline phosphatase family
DSB67_23095	COG0814	amino acid
DSB67_23155	COG0739	heme binding
DSB67_23210	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DSB67_23225	COG3335	DDE superfamily endonuclease
DSB67_23305	COG2814	Major facilitator Superfamily
DSB67_23310	COG1280	lysine exporter protein (LysE YggA)
DSB67_23320	COG2816	NAD+ diphosphatase activity
DSB67_23350	COG1132	(ABC) transporter
DSB67_23360	COG5640	endopeptidase activity
DSB67_23380	COG0583	DNA-binding transcription factor activity
DSB67_23415	COG1120	ATPase activity
DSB67_23420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DSB67_23425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DSB67_23430	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DSB67_23475	COG3005	denitrification pathway
DSB67_23515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSB67_23535	COG0456	acetyltransferase
DSB67_23535	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DSB67_23600	COG0519	Catalyzes the synthesis of GMP from XMP
DSB67_23650	COG4774	siderophore transport
DSB67_23650	COG1629	transport
DSB67_23655	COG2382	esterase
DSB67_23690	COG2801	Transposase and inactivated derivatives
DSB67_23735	COG1028	Short-chain dehydrogenase reductase Sdr
DSB67_23745	COG1720	tRNA m6t6A37 methyltransferase activity
DSB67_23770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DSB67_23785	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DSB67_23800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSB67_23815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSB67_23815	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSB67_23815	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DSB67_23820	COG1105	Belongs to the carbohydrate kinase PfkB family
DSB67_23825	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSB67_23825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSB67_23830	COG1609	Transcriptional regulator
DSB67_23845	COG2200	EAL domain
DSB67_23845	COG2199	diguanylate cyclase activity
DSB67_23845	COG2203	Gaf domain
DSB67_23850	COG0765	amino acid transport
DSB67_23855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSB67_23860	COG0765	amino acid transport
DSB67_23865	COG1126	abc transporter atp-binding protein
DSB67_23875	COG1979	alcohol dehydrogenase
DSB67_23880	COG2207	Transcriptional regulator
DSB67_23895	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DSB67_23905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DSB67_23925	COG0546	phosphoglycolate phosphatase activity
DSB67_23930	COG0840	transmembrane signaling receptor activity
DSB67_23940	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
DSB67_23945	COG0513	Belongs to the DEAD box helicase family
DSB67_23950	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DSB67_23965	COG3038	cytochrome b561
DSB67_23975	COG2116	formate transmembrane transporter activity
DSB67_23985	COG0583	DNA-binding transcription factor activity
DSB67_23995	COG3593	DNA synthesis involved in DNA repair
DSB67_24000	COG0737	Belongs to the 5'-nucleotidase family
DSB67_24005	COG0861	Integral membrane protein TerC family
DSB67_24015	COG0646	methionine synthase
DSB67_24015	COG1410	methionine synthase
DSB67_24020	COG0076	glutamate decarboxylase activity
DSB67_24075	COG2267	carboxylic ester hydrolase activity
DSB67_24080	COG2067	long-chain fatty acid transport protein
DSB67_24090	COG0501	Belongs to the peptidase M48B family
DSB67_24095	COG2050	protein possibly involved in aromatic compounds catabolism
DSB67_24130	COG0484	heat shock protein binding
DSB67_24140	COG5001	Diguanylate cyclase
DSB67_24140	COG3300	MHYT domain
DSB67_24145	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DSB67_24155	COG4181	ATPase activity
DSB67_24160	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DSB67_24170	COG1984	allophanate hydrolase subunit 2
DSB67_24175	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DSB67_24190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DSB67_24205	COG0583	DNA-binding transcription factor activity
DSB67_24210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSB67_24210	COG0045	succinate-CoA ligase (ADP-forming) activity
DSB67_24210	COG1042	CoA-binding domain protein
DSB67_24230	COG0023	Translation Initiation Factor
DSB67_24245	COG3140	Belongs to the UPF0181 family
DSB67_24270	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DSB67_24275	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DSB67_24290	COG0745	RESPONSE REGULATOR receiver
DSB67_24290	COG3706	GGDEF domain
DSB67_24295	COG2203	Gaf domain
DSB67_24295	COG5001	Diguanylate cyclase
DSB67_24295	COG4251	negative regulation of phosphorylation
DSB67_24295	COG3706	GGDEF domain
DSB67_24305	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DSB67_24310	COG4149	molybdate abc transporter
DSB67_24315	COG0725	ABC transporter, periplasmic molybdate-binding protein
DSB67_24325	COG3111	PFAM Bacterial OB fold (BOF) protein
DSB67_24350	COG0602	queuosine metabolic process
DSB67_24355	COG1328	CTP reductase activity
DSB67_24415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DSB67_24420	COG3118	belongs to the thioredoxin family
DSB67_24425	COG2814	Major facilitator Superfamily
DSB67_24455	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DSB67_24470	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DSB67_24470	COG1648	precorrin-2 dehydrogenase activity
DSB67_24530	COG0277	FAD linked oxidase domain protein
DSB67_24535	COG0583	DNA-binding transcription factor activity
DSB67_24550	COG2425	protein containing a von Willebrand factor type A (vWA) domain
DSB67_24565	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
DSB67_24575	COG1288	antiporter activity
DSB67_24585	COG3040	lipid binding
DSB67_24620	COG3469	chitinase activity
DSB67_24630	COG0419	ATPase involved in DNA repair
DSB67_24635	COG0420	3'-5' exonuclease activity
DSB67_24665	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DSB67_24680	COG0840	transmembrane signaling receptor activity
DSB67_24705	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DSB67_24705	COG2755	lipolytic protein G-D-S-L family
DSB67_24745	COG2076	Multidrug Resistance protein
DSB67_24760	COG0671	phosphoesterase, PA-phosphatase related
DSB67_24775	COG2962	Rard protein
DSB67_24785	COG0784	Response regulator, receiver
DSB67_24785	COG0835	chemotaxis
DSB67_24790	COG0778	Nitroreductase
DSB67_24810	COG3179	chitinase
DSB67_24945	COG1522	sequence-specific DNA binding
DSB67_24980	COG0515	serine threonine protein kinase
DSB67_25005	COG3501	Rhs element vgr protein
DSB67_25020	COG2204	response regulator
DSB67_25070	COG0697	spore germination
DSB67_25090	COG0778	Nitroreductase
DSB67_25185	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DSB67_25275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSB67_25285	COG0494	nUDIX hydrolase
DSB67_25295	COG0625	glutathione transferase activity
DSB67_25305	COG0242	peptide deformylase activity
DSB67_25430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DSB67_25435	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DSB67_25440	COG1192	Involved in chromosome partitioning