locus-tag	class	description
MKR81_00010	COG0592	DNA-directed DNA polymerase activity
MKR81_00020	COG0187	DNA topoisomerase II activity
MKR81_00025	COG0071	Belongs to the small heat shock protein (HSP20) family
MKR81_00030	COG3977	Valine--pyruvate aminotransferase
MKR81_00045	COG2119	membrane
MKR81_00055	COG0425	Belongs to the sulfur carrier protein TusA family
MKR81_00070	COG0604	alcohol dehydrogenase
MKR81_00075	COG0183	Belongs to the thiolase family
MKR81_00085	COG1739	Uncharacterized protein family UPF0029
MKR81_00090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MKR81_00140	COG2132	Multicopper oxidase
MKR81_00160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MKR81_00165	COG2104	thiamine diphosphate biosynthetic process
MKR81_00180	COG0006	proline dipeptidase activity
MKR81_00180	COG0006	proline dipeptidase activity
MKR81_00190	COG2814	Major facilitator Superfamily
MKR81_00210	COG3220	belongs to the UPF0276 family
MKR81_00220	COG0210	DNA helicase
MKR81_00225	COG0405	Gamma-glutamyltransferase
MKR81_00230	COG1280	lysine exporter protein (LysE YggA)
MKR81_00250	COG2962	Rard protein
MKR81_00255	COG0514	ATP-dependent DNA helicase (RecQ)
MKR81_00265	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MKR81_00280	COG3118	belongs to the thioredoxin family
MKR81_00295	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MKR81_00300	COG0633	Ferredoxin
MKR81_00350	COG3071	HemY protein
MKR81_00355	COG2959	enzyme of heme biosynthesis
MKR81_00360	COG1587	Uroporphyrinogen-III synthase
MKR81_00370	COG3072	Adenylate cyclase
MKR81_00385	COG0019	diaminopimelate decarboxylase activity
MKR81_00405	COG1011	Hydrolase
MKR81_00410	COG2200	EAL domain
MKR81_00410	COG3287	FIST C domain
MKR81_00410	COG2199	diguanylate cyclase activity
MKR81_00415	COG3148	PFAM DTW domain containing protein
MKR81_00430	COG0561	phosphatase activity
MKR81_00435	COG2267	carboxylic ester hydrolase activity
MKR81_00440	COG1280	lysine exporter protein (LysE YggA)
MKR81_00445	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MKR81_00450	COG0640	Transcriptional regulator
MKR81_00455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MKR81_00500	COG2095	MarC family integral membrane protein
MKR81_00510	COG0742	ribosomal rna small subunit methyltransferase
MKR81_00515	COG0552	protein localization to endoplasmic reticulum
MKR81_00520	COG2884	Cell division ATP-binding protein ftsE
MKR81_00525	COG2177	Part of the ABC transporter FtsEX involved in
MKR81_00540	COG0705	Rhomboid family
MKR81_00545	COG1580	Controls the rotational direction of flagella during chemotaxis
MKR81_00550	COG3161	chorismate lyase activity
MKR81_00560	COG2937	Belongs to the GPAT DAPAT family
MKR81_00575	COG0534	Mate efflux family protein
MKR81_00580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MKR81_00680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKR81_00690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MKR81_00730	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MKR81_00735	COG0250	Participates in transcription elongation, termination and antitermination
MKR81_00750	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MKR81_00770	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
MKR81_00775	COG2816	NAD+ diphosphatase activity
MKR81_00795	COG1573	uracil-dna glycosylase
MKR81_00805	COG3068	Protein conserved in bacteria
MKR81_00810	COG1253	flavin adenine dinucleotide binding
MKR81_00825	COG0151	Belongs to the GarS family
MKR81_00840	COG0789	Transcriptional regulator
MKR81_00845	COG3710	Transcriptional regulator
MKR81_00850	COG0531	amino acid
MKR81_00855	COG1982	Orn Lys Arg decarboxylase major
MKR81_00900	COG2199	diguanylate cyclase activity
MKR81_00905	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MKR81_00910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKR81_00920	COG0439	Biotin carboxylase
MKR81_00925	COG0511	ligase activity, forming carbon-carbon bonds
MKR81_00930	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MKR81_00935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MKR81_00950	COG2814	Major facilitator Superfamily
MKR81_00955	COG2205	protein histidine kinase activity
MKR81_00955	COG2198	Histidine kinase
MKR81_00955	COG0784	Response regulator, receiver
MKR81_00975	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKR81_00985	COG2095	MarC family integral membrane protein
MKR81_00995	COG4232	protein-disulfide reductase activity
MKR81_01000	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MKR81_01005	COG1027	Aspartate ammonia-lyase
MKR81_01010	COG3030	protein affecting phage T7 exclusion by the F plasmid
MKR81_01015	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MKR81_01025	COG2205	protein histidine kinase activity
MKR81_01030	COG0745	RESPONSE REGULATOR receiver
MKR81_01050	COG0534	Mate efflux family protein
MKR81_01075	COG1509	lysine 2,3-aminomutase activity
MKR81_01105	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MKR81_01110	COG1053	succinate dehydrogenase
MKR81_01135	COG4942	peptidase
MKR81_01140	COG1045	serine acetyltransferase
MKR81_01155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MKR81_01160	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MKR81_01170	COG0840	transmembrane signaling receptor activity
MKR81_01175	COG0471	metal ion transport
MKR81_01185	COG1162	GTPase activity
MKR81_01260	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MKR81_01265	COG0802	atpase or kinase
MKR81_01270	COG0860	N-Acetylmuramoyl-L-alanine amidase
MKR81_01275	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MKR81_01290	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MKR81_01295	COG0330	HflC and HflK could
MKR81_01300	COG0330	HflC and HflK could
MKR81_01305	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
MKR81_01310	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MKR81_01315	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
MKR81_01320	COG1017	nitric oxide dioxygenase activity
MKR81_01320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MKR81_01330	COG0557	exoribonuclease II activity
MKR81_01335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKR81_01340	COG0546	phosphoglycolate phosphatase activity
MKR81_01360	COG0512	Glutamine amidotransferase of anthranilate synthase
MKR81_01365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MKR81_01385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MKR81_01390	COG3954	Phosphoribulokinase
MKR81_01400	COG0429	hydrolase of the alpha beta-hydrolase fold
MKR81_01410	COG0488	(ABC) transporter
MKR81_01415	COG2249	NAD(P)H dehydrogenase (quinone) activity
MKR81_01430	COG1047	Peptidyl-prolyl cis-trans
MKR81_01435	COG1446	asparaginase
MKR81_01450	COG0545	Peptidyl-prolyl cis-trans isomerase
MKR81_01455	COG2964	Protein conserved in bacteria
MKR81_01460	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MKR81_01465	COG2923	Belongs to the DsrF TusC family
MKR81_01470	COG2168	tRNA wobble position uridine thiolation
MKR81_01485	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MKR81_01495	COG2906	2 iron, 2 sulfur cluster binding
MKR81_01505	COG0281	malic enzyme
MKR81_01515	COG0626	cystathionine gamma-synthase activity
MKR81_01520	COG0527	aspartate kinase activity
MKR81_01520	COG0460	homoserine dehydrogenase
MKR81_01525	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MKR81_01535	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MKR81_01545	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MKR81_01560	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MKR81_01560	COG0165	Argininosuccinate lyase
MKR81_01570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MKR81_01575	COG0678	peroxiredoxin activity
MKR81_01575	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MKR81_01585	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MKR81_01630	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MKR81_01635	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MKR81_01645	COG2965	DNA replication, synthesis of RNA primer
MKR81_01665	COG0305	Participates in initiation and elongation during chromosome replication
MKR81_01670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MKR81_01680	COG0432	Pfam Uncharacterised protein family UPF0047
MKR81_01695	COG0735	belongs to the Fur family
MKR81_01700	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKR81_01720	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MKR81_01770	COG1410	methionine synthase
MKR81_01770	COG0646	methionine synthase
MKR81_01775	COG0527	aspartate kinase activity
MKR81_01780	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MKR81_01790	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MKR81_01805	COG0629	single-stranded DNA binding
MKR81_01810	COG2200	EAL domain
MKR81_01810	COG2199	diguanylate cyclase activity
MKR81_01835	COG3409	Peptidoglycan-binding domain 1 protein
MKR81_01835	COG3267	Type II secretory pathway component ExeA
MKR81_01845	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MKR81_01850	COG1459	type II secretion system
MKR81_01860	COG2165	general secretion pathway protein
MKR81_01895	COG1077	Cell shape determining protein MreB Mrl
MKR81_01900	COG1792	Involved in formation and maintenance of cell shape
MKR81_01905	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MKR81_01910	COG0424	maF-like protein
MKR81_01920	COG3164	Protein of unknown function
MKR81_01925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MKR81_01930	COG0312	modulator of DNA gyrase
MKR81_01935	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MKR81_01950	COG0564	pseudouridine synthase activity
MKR81_01955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKR81_01965	COG0312	modulator of DNA gyrase
MKR81_01970	COG2239	Acts as a magnesium transporter
MKR81_01975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKR81_01985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKR81_01990	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MKR81_02000	COG1137	ATPase activity
MKR81_02005	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MKR81_02015	COG0517	IMP dehydrogenase activity
MKR81_02015	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MKR81_02025	COG1127	ABC transporter
MKR81_02030	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MKR81_02035	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MKR81_02040	COG2854	intermembrane phospholipid transfer
MKR81_02050	COG5007	Belongs to the BolA IbaG family
MKR81_02060	COG0204	Acyl-transferase
MKR81_02065	COG0251	oxidation-reduction process
MKR81_02100	COG0456	acetyltransferase
MKR81_02110	COG0525	valine-tRNA ligase activity
MKR81_02115	COG2927	DNA polymerase III (CHI subunit)
MKR81_02125	COG0795	lipopolysaccharide-transporting ATPase activity
MKR81_02130	COG0795	lipopolysaccharide-transporting ATPase activity
MKR81_02140	COG1028	Short-chain dehydrogenase reductase Sdr
MKR81_02150	COG0726	polysaccharide deacetylase
MKR81_02155	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MKR81_02165	COG1447	Phosphotransferase system cellobiose-specific component IIA
MKR81_02170	COG1486	melibiose metabolic process
MKR81_02180	COG1609	Transcriptional regulator
MKR81_02185	COG3437	response regulator, receiver
MKR81_02230	COG1012	belongs to the aldehyde dehydrogenase family
MKR81_02330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MKR81_02335	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MKR81_02350	COG0762	integral membrane protein
MKR81_02355	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKR81_02360	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MKR81_02375	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MKR81_02380	COG1678	Uncharacterized ACR, COG1678
MKR81_02385	COG0189	ligase activity
MKR81_02390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MKR81_02395	COG2356	endonuclease I
MKR81_02415	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MKR81_02435	COG0191	fructose-bisphosphate aldolase activity
MKR81_02440	COG0668	transmembrane transport
MKR81_02455	COG0583	DNA-binding transcription factor activity
MKR81_02465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MKR81_02475	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MKR81_02485	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MKR81_02495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MKR81_02500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MKR81_02520	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MKR81_02530	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MKR81_02535	COG1595	DNA-templated transcription, initiation
MKR81_02550	COG3086	response to oxidative stress
MKR81_02570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MKR81_02575	COG1381	Involved in DNA repair and RecF pathway recombination
MKR81_02580	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MKR81_02600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MKR81_02605	COG3956	TIGRFAM MazG family protein
MKR81_02615	COG0148	phosphopyruvate hydratase activity
MKR81_02625	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MKR81_02655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKR81_02665	COG1546	Belongs to the CinA family
MKR81_02670	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MKR81_02685	COG0527	aspartate kinase activity
MKR81_02745	COG3630	sodium ion export across plasma membrane
MKR81_02750	COG0511	ligase activity, forming carbon-carbon bonds
MKR81_02750	COG5016	pyruvate
MKR81_02755	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
MKR81_02765	COG1238	metal cluster binding
MKR81_02770	COG0612	Peptidase, M16
MKR81_02790	COG4536	flavin adenine dinucleotide binding
MKR81_02795	COG4137	Cytochrome C assembly protein
MKR81_02800	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MKR81_02805	COG0228	four-way junction DNA binding
MKR81_02825	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MKR81_02830	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
MKR81_02835	COG0237	dephospho-CoA kinase activity
MKR81_02845	COG1459	type II secretion system
MKR81_02850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MKR81_02875	COG2186	Transcriptional regulator
MKR81_02880	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MKR81_02885	COG0508	dehydrogenase complex catalyzes the overall conversion of
MKR81_02890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MKR81_02905	COG0288	reversible hydration of carbon dioxide
MKR81_02910	COG0659	secondary active sulfate transmembrane transporter activity
MKR81_02915	COG1131	(ABC) transporter
MKR81_02920	COG0842	Transport permease protein
MKR81_02925	COG1560	Kdo2-lipid A biosynthetic process
MKR81_02940	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MKR81_02950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MKR81_02965	COG1643	Atp-dependent helicase
MKR81_02970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MKR81_02975	COG1752	Esterase of the alpha-beta hydrolase superfamily
MKR81_02980	COG1049	propionate catabolic process, 2-methylcitrate cycle
MKR81_02995	COG0004	ammonium transporteR
MKR81_03000	COG1840	ABC-type Fe3 transport system, periplasmic component
MKR81_03010	COG3842	ATPase activity
MKR81_03015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MKR81_03030	COG2971	BadF BadG BcrA BcrD
MKR81_03040	COG4608	Belongs to the ABC transporter superfamily
MKR81_03045	COG0444	Belongs to the ABC transporter superfamily
MKR81_03050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKR81_03060	COG0747	negative chemotaxis
MKR81_03065	COG0784	Response regulator, receiver
MKR81_03065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MKR81_03065	COG2198	Histidine kinase
MKR81_03065	COG2205	protein histidine kinase activity
MKR81_03075	COG0628	permease
MKR81_03095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MKR81_03100	COG0739	heme binding
MKR81_03105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MKR81_03115	COG2027	D-alanyl-D-alanine carboxypeptidase
MKR81_03120	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MKR81_03125	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MKR81_03130	COG1534	Rna-binding protein
MKR81_03140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MKR81_03145	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MKR81_03155	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MKR81_03175	COG0195	Participates in both transcription termination and antitermination
MKR81_03195	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MKR81_03215	COG0534	Mate efflux family protein
MKR81_03220	COG0826	peptidase U32
MKR81_03225	COG0826	peptidase U32
MKR81_03235	COG3154	lipid carrier protein
MKR81_03240	COG3153	acetyltransferase
MKR81_03260	COG3706	GGDEF domain
MKR81_03275	COG0084	hydrolase, TatD family'
MKR81_03280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKR81_03290	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MKR81_03300	COG0813	purine-nucleoside phosphorylase activity
MKR81_03310	COG0560	Phosphoserine phosphatase
MKR81_03320	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MKR81_03325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MKR81_03355	COG1022	Amp-dependent synthetase and ligase
MKR81_03385	COG4964	Belongs to the GSP D family
MKR81_03445	COG0583	DNA-binding transcription factor activity
MKR81_03450	COG3408	Glycogen debranching enzyme
MKR81_03450	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
MKR81_03460	COG0531	amino acid
MKR81_03465	COG2731	YhcH YjgK YiaL family protein
MKR81_03470	COG3250	beta-galactosidase activity
MKR81_03475	COG1609	Transcriptional regulator
MKR81_03480	COG0768	penicillin binding
MKR81_03485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MKR81_03490	COG1085	galactose-1-phosphate uridylyltransferase
MKR81_03500	COG2017	converts alpha-aldose to the beta-anomer
MKR81_03505	COG1609	Transcriptional regulator
MKR81_03520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKR81_03540	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MKR81_03545	COG1349	DNA-binding transcription factor activity
MKR81_03555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MKR81_03560	COG2271	Major facilitator Superfamily
MKR81_03565	COG0584	glycerophosphoryl diester phosphodiesterase
MKR81_03580	COG2171	N-acyltransferase activity
MKR81_03595	COG3141	response to X-ray
MKR81_03615	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MKR81_03620	COG1074	ATP-dependent DNA helicase activity
MKR81_03625	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MKR81_03645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MKR81_03645	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MKR81_03655	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
MKR81_03660	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MKR81_03665	COG2166	iron-sulfur cluster assembly
MKR81_03670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MKR81_03675	COG0693	protein deglycase activity
MKR81_03680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKR81_03700	COG1595	DNA-templated transcription, initiation
MKR81_03730	COG0271	Belongs to the BolA IbaG family
MKR81_03765	COG1477	protein flavinylation
MKR81_03780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKR81_03785	COG0514	ATP-dependent DNA helicase (RecQ)
MKR81_03805	COG0733	neurotransmitter:sodium symporter activity
MKR81_03830	COG1720	tRNA m6t6A37 methyltransferase activity
MKR81_03845	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MKR81_03875	COG3098	single-species biofilm formation
MKR81_03880	COG0564	pseudouridine synthase activity
MKR81_03895	COG0024	Methionine aminopeptidase
MKR81_03920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MKR81_03925	COG0575	Belongs to the CDS family
MKR81_03935	COG0750	zinc metalloprotease
MKR81_03945	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
MKR81_03950	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MKR81_03975	COG0587	DNA-directed DNA polymerase activity
MKR81_03995	COG0347	Belongs to the P(II) protein family
MKR81_04010	COG1388	LysM domain
MKR81_04010	COG0741	lytic transglycosylase activity
MKR81_04020	COG2226	methyltransferase
MKR81_04030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MKR81_04055	COG1960	acyl-CoA dehydrogenase activity
MKR81_04060	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MKR81_04065	COG0121	glutamine amidotransferase
MKR81_04070	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MKR81_04075	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MKR81_04080	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MKR81_04085	COG2233	PERMEase
MKR81_04105	COG1393	Belongs to the ArsC family
MKR81_04110	COG4783	chaperone-mediated protein folding
MKR81_04125	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MKR81_04130	COG2716	regulation of RNA biosynthetic process
MKR81_04135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MKR81_04140	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
MKR81_04160	COG1393	Belongs to the ArsC family
MKR81_04185	COG2837	iron assimilation
MKR81_04190	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKR81_04195	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKR81_04200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKR81_04205	COG1334	flagellar protein FlaG
MKR81_04210	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MKR81_04220	COG1516	flagellar protein fliS
MKR81_04240	COG1677	Flagellar hook-basal body complex protein FliE
MKR81_04250	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MKR81_04305	COG1987	bacterial-type flagellum assembly
MKR81_04310	COG1684	flagellar biosynthetic protein fliR
MKR81_04345	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
MKR81_04350	COG2198	Histidine kinase
MKR81_04350	COG0784	Response regulator, receiver
MKR81_04350	COG0643	Histidine kinase
MKR81_04355	COG2201	protein-glutamate methylesterase activity
MKR81_04360	COG1192	Involved in chromosome partitioning
MKR81_04370	COG0835	chemotaxis
MKR81_04380	COG4133	protoheme IX ABC transporter activity
MKR81_04385	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MKR81_04390	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MKR81_04405	COG1138	Cytochrome C-type biogenesis protein
MKR81_04410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MKR81_04420	COG3088	subunit of a heme lyase
MKR81_04420	COG4235	cytochrome complex assembly
MKR81_04425	COG2853	Lipoprotein
MKR81_04430	COG2067	long-chain fatty acid transport protein
MKR81_04450	COG0183	Belongs to the thiolase family
MKR81_04470	COG2062	phosphohistidine phosphatase, SixA
MKR81_04480	COG2890	protein-(glutamine-N5) methyltransferase activity
MKR81_04490	COG2860	membrane
MKR81_04495	COG3101	peptidyl-lysine hydroxylation
MKR81_04515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MKR81_04520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MKR81_04525	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MKR81_04545	COG0285	dihydrofolate synthase activity
MKR81_04550	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
MKR81_04555	COG1286	toxin biosynthetic process
MKR81_04560	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MKR81_04565	COG0583	DNA-binding transcription factor activity
MKR81_04570	COG0745	RESPONSE REGULATOR receiver
MKR81_04575	COG2832	Protein of unknown function (DUF454)
MKR81_04585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKR81_04595	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MKR81_04600	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MKR81_04605	COG0814	amino acid
MKR81_04610	COG0251	oxidation-reduction process
MKR81_04620	COG2964	Protein conserved in bacteria
MKR81_04630	COG2983	Belongs to the UPF0260 family
MKR81_04635	COG2261	transglycosylase associated protein
MKR81_04640	COG2985	domain, Protein
MKR81_04645	COG0076	glutamate decarboxylase activity
MKR81_04650	COG0668	transmembrane transport
MKR81_04660	COG0346	lactoylglutathione lyase activity
MKR81_04670	COG1785	Belongs to the alkaline phosphatase family
MKR81_04690	COG2226	methyltransferase
MKR81_04710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MKR81_04715	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKR81_04725	COG3139	Protein of unknown function (DUF1315)
MKR81_04730	COG0252	asparaginase activity
MKR81_04735	COG0616	signal peptide processing
MKR81_04740	COG0446	pyridine nucleotide-disulphide oxidoreductase
MKR81_04740	COG1902	pentaerythritol trinitrate reductase activity
MKR81_04745	COG0778	Nitroreductase
MKR81_04750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKR81_04765	COG0123	including yeast histone deacetylase and acetoin utilization protein
MKR81_04775	COG4269	membrane
MKR81_04790	COG3083	sulfuric ester hydrolase activity
MKR81_04815	COG1757	Na H antiporter
MKR81_04820	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MKR81_04825	COG2165	general secretion pathway protein
MKR81_04830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MKR81_04835	COG2095	MarC family integral membrane protein
MKR81_04840	COG1012	belongs to the aldehyde dehydrogenase family
MKR81_04840	COG1454	alcohol dehydrogenase
MKR81_04860	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MKR81_04865	COG4974	Belongs to the 'phage' integrase family
MKR81_04890	COG1403	HNH endonuclease
MKR81_04980	COG2003	Belongs to the UPF0758 family
MKR81_05040	COG1278	Cold shock
MKR81_05065	COG3457	Alanine racemase
MKR81_05075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKR81_05105	COG3504	Conjugal transfer protein
MKR81_05110	COG3736	Type IV secretory pathway, component VirB8
MKR81_05135	COG3451	type IV secretory pathway VirB4
MKR81_05175	COG2056	Na+-H+ antiporter family
MKR81_05185	COG2885	chlorophyll binding
MKR81_05195	COG0346	lactoylglutathione lyase activity
MKR81_05215	COG1566	PFAM secretion protein HlyD family protein
MKR81_05240	COG2205	protein histidine kinase activity
MKR81_05240	COG0784	Response regulator, receiver
MKR81_05250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MKR81_05280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MKR81_05285	COG4660	Part of a membrane complex involved in electron transport
MKR81_05290	COG4659	FMN binding
MKR81_05295	COG4658	electron transport chain
MKR81_05300	COG4656	Part of a membrane complex involved in electron transport
MKR81_05310	COG4657	Part of a membrane complex involved in electron transport
MKR81_05355	COG0556	nucleotide-excision repair
MKR81_05370	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MKR81_05375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MKR81_05380	COG0521	Mo-molybdopterin cofactor biosynthetic process
MKR81_05390	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MKR81_05395	COG0314	molybdopterin synthase activity
MKR81_05405	COG0601	transmembrane transport
MKR81_05410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKR81_05415	COG0444	Belongs to the ABC transporter superfamily
MKR81_05425	COG0435	Glutathione S-transferase
MKR81_05430	COG3174	membrane
MKR81_05435	COG0280	phosphate acetyltransferase
MKR81_05435	COG0857	belongs to the CobB CobQ family
MKR81_05455	COG4120	Belongs to the binding-protein-dependent transport system permease family
MKR81_05460	COG1122	ATPase activity
MKR81_05465	COG0366	Alpha amylase catalytic
MKR81_05475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKR81_05480	COG0653	protein targeting
MKR81_05485	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MKR81_05495	COG2186	Transcriptional regulator
MKR81_05525	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
MKR81_05530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MKR81_05535	COG0659	secondary active sulfate transmembrane transporter activity
MKR81_05540	COG1530	ribonuclease E activity
MKR81_05545	COG0564	pseudouridine synthase activity
MKR81_05550	COG0424	maF-like protein
MKR81_05555	COG1399	metal-binding, possibly nucleic acid-binding protein
MKR81_05570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKR81_05600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MKR81_05615	COG0084	hydrolase, TatD family'
MKR81_05620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKR81_05620	COG1263	PTS System
MKR81_05635	COG0733	neurotransmitter:sodium symporter activity
MKR81_05650	COG4667	esterase of the alpha-beta hydrolase superfamily
MKR81_05675	COG2272	Belongs to the type-B carboxylesterase lipase family
MKR81_05680	COG3710	Transcriptional regulator
MKR81_05695	COG1940	carbohydrate kinase activity
MKR81_05700	COG0835	chemotaxis
MKR81_05700	COG0784	Response regulator, receiver
MKR81_05720	COG1028	Short-chain dehydrogenase reductase Sdr
MKR81_05725	COG0616	signal peptide processing
MKR81_05735	COG0539	negative regulation of cytoplasmic translation
MKR81_05745	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
MKR81_05750	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MKR81_05760	COG4166	transmembrane transport
MKR81_05780	COG3009	Protein conserved in bacteria
MKR81_05790	COG2995	paraquat-inducible protein a
MKR81_05795	COG1609	Transcriptional regulator
MKR81_05800	COG3250	beta-galactosidase activity
MKR81_05810	COG4580	involved in the transport of maltose and maltodextrins
MKR81_05820	COG2211	Major facilitator Superfamily
MKR81_05825	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MKR81_05840	COG4232	protein-disulfide reductase activity
MKR81_05845	COG3118	belongs to the thioredoxin family
MKR81_05890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKR81_05910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKR81_05920	COG0577	efflux transmembrane transporter activity
MKR81_05925	COG1136	(ABC) transporter
MKR81_05925	COG0577	efflux transmembrane transporter activity
MKR81_05930	COG0577	efflux transmembrane transporter activity
MKR81_05930	COG1136	(ABC) transporter
MKR81_05945	COG2176	DNA-directed DNA polymerase activity
MKR81_06020	COG5002	protein histidine kinase activity
MKR81_06020	COG3850	Histidine kinase
MKR81_06025	COG0745	RESPONSE REGULATOR receiver
MKR81_06030	COG0463	Glycosyl transferase, family 2
MKR81_06035	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MKR81_06045	COG0840	transmembrane signaling receptor activity
MKR81_06070	COG2175	clavaminate synthase activity
MKR81_06080	COG2964	Protein conserved in bacteria
MKR81_06085	COG0251	oxidation-reduction process
MKR81_06095	COG0446	pyridine nucleotide-disulphide oxidoreductase
MKR81_06105	COG1032	radical SAM domain protein
MKR81_06110	COG5001	Diguanylate cyclase
MKR81_06110	COG1716	ATPase activity
MKR81_06140	COG2350	Protein conserved in bacteria
MKR81_06170	COG1301	dicarboxylic acid transport
MKR81_06175	COG0159	tryptophan synthase activity
MKR81_06185	COG0134	indole-3-glycerol-phosphate synthase activity
MKR81_06185	COG0135	phosphoribosylanthranilate isomerase activity
MKR81_06195	COG0512	Glutamine amidotransferase of anthranilate synthase
MKR81_06200	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKR81_06210	COG0613	PHP domain protein
MKR81_06215	COG0009	L-threonylcarbamoyladenylate synthase
MKR81_06225	COG1187	pseudouridine synthase activity
MKR81_06245	COG0417	DNA replication proofreading
MKR81_06250	COG2197	response regulator
MKR81_06255	COG0322	excinuclease ABC activity
MKR81_06295	COG0019	diaminopimelate decarboxylase activity
MKR81_06310	COG1058	Belongs to the CinA family
MKR81_06310	COG1546	Belongs to the CinA family
MKR81_06320	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKR81_06325	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKR81_06350	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
MKR81_06360	COG0437	4 iron, 4 sulfur cluster binding
MKR81_06365	COG3301	Polysulphide reductase, NrfD
MKR81_06370	COG1138	Cytochrome C-type biogenesis protein
MKR81_06380	COG4235	cytochrome complex assembly
MKR81_06380	COG3088	subunit of a heme lyase
MKR81_06415	COG2989	Protein conserved in bacteria
MKR81_06420	COG3108	Peptidase M15
MKR81_06425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MKR81_06440	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MKR81_06465	COG1846	Transcriptional regulator
MKR81_06470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MKR81_06475	COG0840	transmembrane signaling receptor activity
MKR81_06495	COG1448	Aminotransferase
MKR81_06515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MKR81_06530	COG0017	Asparaginyl-tRNA synthetase
MKR81_06540	COG0720	synthase
MKR81_06545	COG2197	response regulator
MKR81_06565	COG1760	l-serine dehydratase
MKR81_06570	COG0814	amino acid
MKR81_06590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKR81_06605	COG3106	COG3106 Predicted ATPase
MKR81_06620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKR81_06770	COG0494	nUDIX hydrolase
MKR81_07040	COG1683	Conserved Protein
MKR81_07135	COG4221	oxidoreductase activity
MKR81_07150	COG3340	Belongs to the peptidase S51 family
MKR81_07165	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKR81_07180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MKR81_07180	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MKR81_07190	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MKR81_07195	COG1609	Transcriptional regulator
MKR81_07205	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MKR81_07220	COG0596	Alpha beta hydrolase
MKR81_07240	COG0471	metal ion transport
MKR81_07245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MKR81_07245	COG4191	Histidine kinase
MKR81_07265	COG1280	lysine exporter protein (LysE YggA)
MKR81_07270	COG1328	CTP reductase activity
MKR81_07275	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MKR81_07285	COG0861	Integral membrane protein TerC family
MKR81_07295	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MKR81_07305	COG1454	alcohol dehydrogenase
MKR81_07310	COG0814	amino acid
MKR81_07330	COG1132	(ABC) transporter
MKR81_07335	COG1132	(ABC) transporter
MKR81_07340	COG2165	general secretion pathway protein
MKR81_07345	COG0583	DNA-binding transcription factor activity
MKR81_07355	COG0673	inositol 2-dehydrogenase activity
MKR81_07370	COG0443	Heat shock 70 kDa protein
MKR81_07375	COG0443	Heat shock 70 kDa protein
MKR81_07415	COG3227	Zinc metalloprotease (Elastase)
MKR81_07425	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MKR81_07430	COG1643	Atp-dependent helicase
MKR81_07455	COG3063	Type IV pilus biogenesis stability protein PilW
MKR81_07485	COG0531	amino acid
MKR81_07490	COG1280	lysine exporter protein (LysE YggA)
MKR81_07500	COG0702	epimerase
MKR81_07505	COG1560	Kdo2-lipid A biosynthetic process
MKR81_07525	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MKR81_07530	COG1280	lysine exporter protein (LysE YggA)
MKR81_07565	COG1115	amino acid carrier protein
MKR81_07590	COG1368	sulfuric ester hydrolase activity
MKR81_07605	COG0215	cysteine-tRNA ligase activity
MKR81_07610	COG0534	Mate efflux family protein
MKR81_07615	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
MKR81_07625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MKR81_07630	COG1858	cytochrome C peroxidase
MKR81_07635	COG1404	Belongs to the peptidase S8 family
MKR81_07640	COG3227	Zinc metalloprotease (Elastase)
MKR81_07655	COG0583	DNA-binding transcription factor activity
MKR81_07660	COG0702	epimerase
MKR81_07665	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MKR81_07670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MKR81_07675	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MKR81_07700	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MKR81_07705	COG0667	Aldo Keto reductase
MKR81_07720	COG0583	DNA-binding transcription factor activity
MKR81_07725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MKR81_07730	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MKR81_07735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MKR81_07740	COG0679	Auxin Efflux Carrier
MKR81_07780	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MKR81_07785	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
MKR81_07820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKR81_07840	COG3290	protein histidine kinase activity
MKR81_07845	COG4565	transcriptional regulatory protein
MKR81_07850	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MKR81_07855	COG0363	glucosamine-6-phosphate deaminase activity
MKR81_07860	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MKR81_07895	COG3284	Transcriptional regulator
MKR81_07900	COG1012	belongs to the aldehyde dehydrogenase family
MKR81_07905	COG2358	TRAP transporter, solute receptor (TAXI family
MKR81_07910	COG0840	transmembrane signaling receptor activity
MKR81_07915	COG0730	response to heat
MKR81_07945	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MKR81_07950	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MKR81_08060	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MKR81_08065	COG0372	Belongs to the citrate synthase family
MKR81_08075	COG2828	Protein conserved in bacteria
MKR81_08110	COG0561	phosphatase activity
MKR81_08115	COG0602	queuosine metabolic process
MKR81_08125	COG3706	GGDEF domain
MKR81_08175	COG0840	transmembrane signaling receptor activity
MKR81_08180	COG1254	Belongs to the acylphosphatase family
MKR81_08185	COG2920	part of a sulfur-relay system
MKR81_08195	COG0670	Belongs to the BI1 family
MKR81_08200	COG1126	abc transporter atp-binding protein
MKR81_08205	COG0765	amino acid transport
MKR81_08210	COG4597	amino acid ABC transporter
MKR81_08215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MKR81_08230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MKR81_08255	COG3008	intermembrane lipid transfer
MKR81_08260	COG2995	paraquat-inducible protein a
MKR81_08265	COG1132	(ABC) transporter
MKR81_08270	COG1956	GAF domain-containing protein
MKR81_08275	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
MKR81_08290	COG0308	aminopeptidase N
MKR81_08300	COG2902	Dehydrogenase
MKR81_08325	COG0488	(ABC) transporter
MKR81_08345	COG1067	ATP-dependent peptidase activity
MKR81_08390	COG3278	Belongs to the heme-copper respiratory oxidase family
MKR81_08405	COG2010	Cytochrome c
MKR81_08415	COG2217	Heavy metal translocating P-type atpase
MKR81_08430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MKR81_08435	COG0589	response to stress
MKR81_08460	COG3842	ATPase activity
MKR81_08470	COG1177	transmembrane transport
MKR81_08480	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MKR81_08485	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MKR81_08505	COG0437	4 iron, 4 sulfur cluster binding
MKR81_08510	COG3383	formate dehydrogenase (NAD+) activity
MKR81_08510	COG0243	molybdopterin cofactor binding
MKR81_08520	COG3381	protein complex oligomerization
MKR81_08540	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MKR81_08545	COG2194	sulfuric ester hydrolase activity
MKR81_08550	COG0584	glycerophosphoryl diester phosphodiesterase
MKR81_08555	COG0488	(ABC) transporter
MKR81_08570	COG4191	Histidine kinase
MKR81_08575	COG2204	response regulator
MKR81_08585	COG4662	Binding-protein-dependent transport system inner membrane component
MKR81_08590	COG3842	ATPase activity
MKR81_08600	COG0303	'Molybdopterin
MKR81_08610	COG1940	carbohydrate kinase activity
MKR81_08615	COG3148	PFAM DTW domain containing protein
MKR81_08660	COG0840	transmembrane signaling receptor activity
MKR81_08660	COG3290	protein histidine kinase activity
MKR81_08665	COG0791	NLP P60 protein
MKR81_08675	COG3706	GGDEF domain
MKR81_08680	COG2201	protein-glutamate methylesterase activity
MKR81_08695	COG0307	riboflavin synthase, alpha
MKR81_08700	COG0534	Mate efflux family protein
MKR81_08710	COG1793	dna ligase
MKR81_08720	COG2885	chlorophyll binding
MKR81_08740	COG2204	response regulator
MKR81_08745	COG0438	transferase activity, transferring glycosyl groups
MKR81_08750	COG0438	transferase activity, transferring glycosyl groups
MKR81_08780	COG0438	transferase activity, transferring glycosyl groups
MKR81_08785	COG1215	transferase activity, transferring glycosyl groups
MKR81_08790	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MKR81_08800	COG3064	Membrane
MKR81_08825	COG5001	Diguanylate cyclase
MKR81_08825	COG3300	MHYT domain
MKR81_08830	COG3437	response regulator, receiver
MKR81_08830	COG3850	Histidine kinase
MKR81_08830	COG2205	protein histidine kinase activity
MKR81_08830	COG4999	Histidine kinase
MKR81_08850	COG0110	maltose O-acetyltransferase activity
MKR81_08875	COG1846	Transcriptional regulator
MKR81_08890	COG3247	response to pH
MKR81_08895	COG0668	transmembrane transport
MKR81_08905	COG1404	Belongs to the peptidase S8 family
MKR81_08935	COG0745	RESPONSE REGULATOR receiver
MKR81_08985	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MKR81_08985	COG2199	diguanylate cyclase activity
MKR81_09000	COG0668	transmembrane transport
MKR81_09025	COG0625	glutathione transferase activity
MKR81_09035	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
MKR81_09050	COG2195	Cleaves the N-terminal amino acid of tripeptides
MKR81_09060	COG0601	transmembrane transport
MKR81_09065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKR81_09070	COG0444	Belongs to the ABC transporter superfamily
MKR81_09105	COG0813	purine-nucleoside phosphorylase activity
MKR81_09130	COG1451	nucleotide metabolic process
MKR81_09135	COG5492	domain, Protein
MKR81_09135	COG4932	domain protein
MKR81_09150	COG0745	RESPONSE REGULATOR receiver
MKR81_09160	COG2198	Histidine kinase
MKR81_09160	COG2205	protein histidine kinase activity
MKR81_09160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MKR81_09160	COG0784	Response regulator, receiver
MKR81_09225	COG2165	general secretion pathway protein
MKR81_09250	COG0583	DNA-binding transcription factor activity
MKR81_09285	COG4139	cobalamin transport
MKR81_09310	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MKR81_09320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MKR81_09325	COG0702	epimerase
MKR81_09330	COG1823	symporter activity
MKR81_09340	COG2925	Exonuclease
MKR81_09350	COG1346	cytolysis
MKR81_09410	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKR81_09415	COG4605	iron ion homeostasis
MKR81_09420	COG4607	ABC-type enterochelin transport system periplasmic component
MKR81_09425	COG4774	siderophore transport
MKR81_09445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MKR81_09460	COG1132	(ABC) transporter
MKR81_09465	COG1535	isochorismatase
MKR81_09465	COG3433	isochorismatase activity
MKR81_09470	COG0072	phenylalanine-tRNA ligase activity
MKR81_09470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKR81_09480	COG3706	GGDEF domain
MKR81_09520	COG0251	oxidation-reduction process
MKR81_09560	COG2188	Transcriptional regulator
MKR81_09570	COG0010	Belongs to the arginase family
MKR81_09580	COG2986	histidine ammonia-lyase
MKR81_09625	COG0277	FAD linked oxidase domain protein
MKR81_09625	COG0247	lactate metabolic process
MKR81_09685	COG1643	Atp-dependent helicase
MKR81_09695	COG2949	membrane
MKR81_09700	COG0471	metal ion transport
MKR81_09705	COG3706	GGDEF domain
MKR81_09725	COG0492	ferredoxin-NADP+ reductase activity
MKR81_09730	COG4988	ABC transporter
MKR81_09735	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MKR81_09745	COG0583	DNA-binding transcription factor activity
MKR81_09750	COG2200	EAL domain
MKR81_09780	COG5001	Diguanylate cyclase
MKR81_09790	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MKR81_09800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MKR81_09800	COG4191	Histidine kinase
MKR81_09815	COG3070	regulator of competence-specific genes
MKR81_09825	COG2431	L-lysine efflux transmembrane transporter activity
MKR81_09835	COG0076	glutamate decarboxylase activity
MKR81_09850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MKR81_09860	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MKR81_09895	COG0534	Mate efflux family protein
MKR81_09900	COG0702	epimerase
MKR81_09905	COG4667	esterase of the alpha-beta hydrolase superfamily
MKR81_09915	COG2814	Major facilitator Superfamily
MKR81_09920	COG1187	pseudouridine synthase activity
MKR81_09925	COG1061	Type III restriction enzyme res subunit
MKR81_09930	COG3706	GGDEF domain
MKR81_09985	COG3313	Fe-S protein
MKR81_09995	COG0659	secondary active sulfate transmembrane transporter activity
MKR81_10020	COG0493	'glutamate synthase
MKR81_10030	COG0398	Pfam SNARE associated Golgi protein
MKR81_10035	COG4134	Bacterial extracellular solute-binding protein
MKR81_10040	COG4135	transport system, permease component
MKR81_10045	COG4136	ATPase activity
MKR81_10050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MKR81_10060	COG2814	Major facilitator Superfamily
MKR81_10065	COG3604	Transcriptional regulator
MKR81_10070	COG1151	hydroxylamine reductase activity
MKR81_10075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MKR81_10085	COG0564	pseudouridine synthase activity
MKR81_10095	COG0733	neurotransmitter:sodium symporter activity
MKR81_10105	COG0626	cystathionine gamma-synthase activity
MKR81_10110	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MKR81_10130	COG2818	Glycosylase
MKR81_10140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKR81_10150	COG1983	PspC domain protein
MKR81_10160	COG1842	Phage shock protein A
MKR81_10165	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MKR81_10175	COG4168	peptide transport system, permease
MKR81_10180	COG4171	peptide transport system, permease
MKR81_10190	COG4172	Belongs to the ABC transporter superfamily
MKR81_10200	COG1227	inorganic diphosphatase activity
MKR81_10215	COG0243	molybdopterin cofactor binding
MKR81_10220	COG3005	denitrification pathway
MKR81_10225	COG4459	periplasmic nitrate reductase
MKR81_10230	COG0390	transport system, permease component
MKR81_10240	COG2116	formate transmembrane transporter activity
MKR81_10265	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MKR81_10270	COG1435	thymidine kinase activity
MKR81_10275	COG0215	cysteine-tRNA ligase activity
MKR81_10280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MKR81_10285	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MKR81_10290	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MKR81_10295	COG3012	SEC-C Motif Domain Protein
MKR81_10300	COG0140	phosphoribosyl-ATP diphosphatase activity
MKR81_10300	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MKR81_10310	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MKR81_10315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MKR81_10320	COG0131	Imidazoleglycerol-phosphate dehydratase
MKR81_10320	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MKR81_10330	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MKR81_10345	COG1757	Na H antiporter
MKR81_10355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKR81_10375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MKR81_10395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MKR81_10410	COG0300	oxidoreductase activity
MKR81_10435	COG2226	methyltransferase
MKR81_10455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MKR81_10475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MKR81_10485	COG1674	ftsk spoiiie
MKR81_10495	COG0686	Belongs to the AlaDH PNT family
MKR81_10505	COG0583	DNA-binding transcription factor activity
MKR81_10530	COG0402	S-adenosylhomocysteine deaminase activity
MKR81_10535	COG4934	collagen metabolic process
MKR81_10540	COG0270	DNA (cytosine-5-)-methyltransferase activity
MKR81_10550	COG3568	Endonuclease Exonuclease Phosphatase
MKR81_10570	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
MKR81_10585	COG1288	antiporter activity
MKR81_10595	COG2186	Transcriptional regulator
MKR81_10605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MKR81_10610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKR81_10630	COG2824	Alkylphosphonate utilization operon protein PhnA
MKR81_10650	COG3119	arylsulfatase activity
MKR81_10680	COG0457	Tetratricopeptide repeat
MKR81_10750	COG4790	Type iii secretion
MKR81_10755	COG4794	Type iii secretion
MKR81_10760	COG4791	protein targeting
MKR81_10765	COG4792	protein secretion
MKR81_10780	COG3177	Filamentation induced by cAMP protein fic
MKR81_10810	COG4669	(LipO)protein
MKR81_10915	COG2205	protein histidine kinase activity
MKR81_10915	COG0784	Response regulator, receiver
MKR81_10925	COG0754	glutathionylspermidine amidase activity
MKR81_10935	COG3766	membrane
MKR81_10950	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
MKR81_10955	COG2885	chlorophyll binding
MKR81_10960	COG0823	Involved in the tonB-independent uptake of proteins
MKR81_10975	COG0811	peptide transport
MKR81_10980	COG0824	Thioesterase
MKR81_10990	COG4890	Cyd operon protein YbgT
MKR81_10995	COG1294	oxidase, subunit
MKR81_11000	COG1271	oxidase subunit
MKR81_11010	COG0632	four-way junction helicase activity
MKR81_11015	COG0840	transmembrane signaling receptor activity
MKR81_11030	COG1801	Protein of unknown function DUF72
MKR81_11045	COG0189	ligase activity
MKR81_11045	COG4067	protein conserved in archaea
MKR81_11070	COG0318	PFAM AMP-dependent synthetase and ligase
MKR81_11085	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MKR81_11090	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
MKR81_11100	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MKR81_11105	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MKR81_11110	COG0745	RESPONSE REGULATOR receiver
MKR81_11125	COG3070	regulator of competence-specific genes
MKR81_11145	COG0297	glycogen (starch) synthase activity
MKR81_11150	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MKR81_11155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKR81_11185	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MKR81_11190	COG0542	response to heat
MKR81_11200	COG1278	Cold shock
MKR81_11210	COG1187	pseudouridine synthase activity
MKR81_11215	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
MKR81_11225	COG1199	ATP-dependent helicase activity
MKR81_11230	COG0730	response to heat
MKR81_11235	COG3923	Primosomal replication protein n
MKR81_11245	COG0708	Exodeoxyribonuclease III
MKR81_11280	COG1882	Formate acetyltransferase
MKR81_11290	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MKR81_11305	COG2766	serine protein kinase
MKR81_11310	COG2718	Belongs to the UPF0229 family
MKR81_11315	COG2719	SpoVR family
MKR81_11335	COG1132	(ABC) transporter
MKR81_11340	COG0658	competence protein
MKR81_11340	COG2333	competence protein COMEC
MKR81_11350	COG4591	ABC-type transport system involved in lipoprotein release permease component
MKR81_11355	COG1136	(ABC) transporter
MKR81_11360	COG4591	ABC-type transport system involved in lipoprotein release permease component
MKR81_11370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MKR81_11385	COG1252	NADH dehydrogenase
MKR81_11415	COG0537	adenosine 5'-monophosphoramidase activity
MKR81_11435	COG2217	Heavy metal translocating P-type atpase
MKR81_11445	COG0516	GMP reductase activity
MKR81_11445	COG0517	IMP dehydrogenase activity
MKR81_11450	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
MKR81_11455	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MKR81_11460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKR81_11470	COG3706	GGDEF domain
MKR81_11485	COG3126	Type III secretion system lipoprotein chaperone (YscW)
MKR81_11490	COG1946	Acyl-CoA thioesterase
MKR81_11495	COG1522	sequence-specific DNA binding
MKR81_11520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MKR81_11565	COG2855	membrane
MKR81_11575	COG0583	DNA-binding transcription factor activity
MKR81_11580	COG2190	(PTS) system
MKR81_11580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKR81_11580	COG1263	PTS System
MKR81_11595	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MKR81_11600	COG0596	Alpha beta hydrolase
MKR81_11610	COG1169	isochorismate synthase
MKR81_11615	COG0436	Aminotransferase
MKR81_11620	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
MKR81_11640	COG1555	photosystem II stabilization
MKR81_11645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MKR81_11650	COG0776	regulation of translation
MKR81_11655	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MKR81_11690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MKR81_11695	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MKR81_11700	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MKR81_11720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MKR81_11725	COG0569	domain protein
MKR81_11730	COG0513	Belongs to the DEAD box helicase family
MKR81_11735	COG1253	flavin adenine dinucleotide binding
MKR81_11740	COG4771	TonB-dependent receptor
MKR81_11745	COG2977	Belongs to the P-Pant transferase superfamily
MKR81_11755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MKR81_11755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MKR81_11760	COG1535	isochorismatase
MKR81_11760	COG3433	isochorismatase activity
MKR81_11765	COG1021	2,3-dihydroxybenzoate-AMP ligase
MKR81_11770	COG1169	isochorismate synthase
MKR81_11780	COG1028	Short-chain dehydrogenase reductase Sdr
MKR81_11890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKR81_11895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKR81_11915	COG1216	Glycosyl transferase, family 2
MKR81_11920	COG2986	histidine ammonia-lyase
MKR81_11955	COG1028	Short-chain dehydrogenase reductase Sdr
MKR81_11980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKR81_11990	COG2951	lytic endotransglycosylase activity
MKR81_12005	COG2894	cell division
MKR81_12010	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MKR81_12015	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MKR81_12020	COG0318	PFAM AMP-dependent synthetase and ligase
MKR81_12025	COG2267	carboxylic ester hydrolase activity
MKR81_12030	COG3065	identical protein binding
MKR81_12040	COG1214	PFAM Peptidase M22, glycoprotease
MKR81_12045	COG1199	ATP-dependent helicase activity
MKR81_12055	COG0788	formyltetrahydrofolate deformylase activity
MKR81_12070	COG3102	Protein conserved in bacteria
MKR81_12100	COG1918	ferrous iron import across plasma membrane
MKR81_12105	COG4977	sequence-specific DNA binding
MKR81_12110	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
MKR81_12115	COG1121	(ABC) transporter
MKR81_12120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MKR81_12135	COG0508	dehydrogenase complex catalyzes the overall conversion of
MKR81_12140	COG0567	Dehydrogenase, E1 component
MKR81_12150	COG1053	succinate dehydrogenase
MKR81_12155	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MKR81_12170	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MKR81_12180	COG0033	Phosphoglucomutase
MKR81_12185	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
MKR81_12190	COG0596	Alpha beta hydrolase
MKR81_12210	COG0735	belongs to the Fur family
MKR81_12220	COG2190	(PTS) system
MKR81_12220	COG1263	PTS System
MKR81_12220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKR81_12225	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MKR81_12230	COG1846	Transcriptional regulator
MKR81_12230	COG1940	carbohydrate kinase activity
MKR81_12235	COG4651	solute:proton antiporter activity
MKR81_12235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MKR81_12240	COG0367	asparagine synthase
MKR81_12250	COG3104	oligopeptide transport
MKR81_12255	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MKR81_12270	COG3710	Transcriptional regulator
MKR81_12290	COG0622	Phosphoesterase
MKR81_12320	COG1090	epimerase
MKR81_12325	COG0300	oxidoreductase activity
MKR81_12330	COG3118	belongs to the thioredoxin family
MKR81_12335	COG0457	Tetratricopeptide repeat
MKR81_12335	COG3118	belongs to the thioredoxin family
MKR81_12340	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MKR81_12345	COG1215	transferase activity, transferring glycosyl groups
MKR81_12350	COG1215	transferase activity, transferring glycosyl groups
MKR81_12355	COG1192	Involved in chromosome partitioning
MKR81_12375	COG2194	sulfuric ester hydrolase activity
MKR81_12380	COG0330	HflC and HflK could
MKR81_12415	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
MKR81_12420	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MKR81_12425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKR81_12430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MKR81_12435	COG2190	(PTS) system
MKR81_12440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKR81_12445	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKR81_12450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKR81_12470	COG1705	Flagellar rod assembly protein muramidase FlgJ
MKR81_12470	COG3951	Flagellar rod assembly protein muramidase FlgJ
MKR81_12475	COG1706	bacterial-type flagellum-dependent cell motility
MKR81_12480	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MKR81_12490	COG4787	bacterial-type flagellum-dependent cell motility
MKR81_12495	COG1749	Flagellar hook protein flgE
MKR81_12505	COG1558	bacterial-type flagellum-dependent cell motility
MKR81_12510	COG1815	bacterial-type flagellum-dependent cell motility
MKR81_12515	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MKR81_12520	COG0784	Response regulator, receiver
MKR81_12520	COG0835	chemotaxis
MKR81_12575	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
MKR81_12585	COG2217	Heavy metal translocating P-type atpase
MKR81_12585	COG2608	mercury ion transmembrane transporter activity
MKR81_12625	COG2840	Smr protein MutS2
MKR81_12630	COG1187	pseudouridine synthase activity
MKR81_12635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MKR81_12640	COG0737	Belongs to the 5'-nucleotidase family
MKR81_12650	COG2912	Transglutaminase-like superfamily
MKR81_12655	COG3094	Invasion gene expression up-regulator, SirB
MKR81_12660	COG2890	protein-(glutamine-N5) methyltransferase activity
MKR81_12685	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKR81_12795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MKR81_12805	COG1702	phosphate starvation-inducible protein PhoH
MKR81_12815	COG4535	Mg2 and Co2 transporter CorC
MKR81_12820	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MKR81_12825	COG2888	peptidyl-tyrosine sulfation
MKR81_12835	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
MKR81_12840	COG1466	dna polymerase III delta subunit
MKR81_12845	COG0799	negative regulation of ribosome biogenesis
MKR81_12855	COG0768	penicillin binding
MKR81_12860	COG0772	Belongs to the SEDS family
MKR81_12865	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MKR81_12870	COG1686	Belongs to the peptidase S11 family
MKR81_12890	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MKR81_12895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKR81_12900	COG0366	Alpha amylase catalytic
MKR81_12905	COG1263	PTS System
MKR81_12905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKR81_12915	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MKR81_12920	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MKR81_12925	COG2011	ABC-type metal ion transport system permease component
MKR81_12930	COG1464	Belongs to the NlpA lipoprotein family
MKR81_12940	COG0737	Belongs to the 5'-nucleotidase family
MKR81_12945	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
MKR81_12970	COG1611	Belongs to the LOG family
MKR81_12990	COG2363	Small membrane protein
MKR81_13000	COG0583	DNA-binding transcription factor activity
MKR81_13015	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MKR81_13025	COG0142	geranyltranstransferase activity
MKR81_13035	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MKR81_13040	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MKR81_13065	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MKR81_13065	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MKR81_13070	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MKR81_13075	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MKR81_13090	COG1073	alpha beta
MKR81_13100	COG2252	PERMEase
MKR81_13105	COG2195	Cleaves the N-terminal amino acid of tripeptides
MKR81_13130	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKR81_13130	COG0047	phosphoribosylformylglycinamidine synthase activity
MKR81_13140	COG0590	tRNA wobble adenosine to inosine editing
MKR81_13145	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MKR81_13165	COG4969	Belongs to the N-Me-Phe pilin family
MKR81_13185	COG1301	dicarboxylic acid transport
MKR81_13200	COG0497	DNA recombination
MKR81_13205	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MKR81_13210	COG2914	Belongs to the UPF0125 (RnfH) family
MKR81_13215	COG2867	negative regulation of translational initiation
MKR81_13230	COG0583	DNA-binding transcription factor activity
MKR81_13235	COG1289	transmembrane transporter activity
MKR81_13255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MKR81_13265	COG0668	transmembrane transport
MKR81_13285	COG0583	DNA-binding transcription factor activity
MKR81_13295	COG1115	amino acid carrier protein
MKR81_13300	COG1584	GPR1 FUN34 yaaH family protein
MKR81_13310	COG1757	Na H antiporter
MKR81_13320	COG0517	IMP dehydrogenase activity
MKR81_13320	COG0516	GMP reductase activity
MKR81_13335	COG2203	Gaf domain
MKR81_13335	COG2199	diguanylate cyclase activity
MKR81_13350	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MKR81_13355	COG2976	Protein conserved in bacteria
MKR81_13390	COG2975	iron-sulfur cluster assembly
MKR81_13395	COG0633	Ferredoxin
MKR81_13410	COG0316	Belongs to the HesB IscA family
MKR81_13415	COG0822	iron-sulfur transferase activity
MKR81_13430	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MKR81_13435	COG0483	inositol monophosphate 1-phosphatase activity
MKR81_13445	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MKR81_13450	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MKR81_13455	COG1862	Preprotein translocase
MKR81_13480	COG0517	IMP dehydrogenase activity
MKR81_13490	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MKR81_13495	COG0583	DNA-binding transcription factor activity
MKR81_13500	COG0450	alkyl hydroperoxide reductase
MKR81_13530	COG0704	Plays a role in the regulation of phosphate uptake
MKR81_13535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MKR81_13540	COG0581	inorganic phosphate transmembrane transporter activity
MKR81_13545	COG0573	inorganic phosphate transmembrane transporter activity
MKR81_13550	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MKR81_13555	COG0248	Ppx GppA phosphatase
MKR81_13565	COG5002	protein histidine kinase activity
MKR81_13570	COG0745	RESPONSE REGULATOR receiver
MKR81_13580	COG0826	peptidase U32
MKR81_13585	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MKR81_13640	COG0542	response to heat
MKR81_13650	COG0564	pseudouridine synthase activity
MKR81_13655	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MKR81_13660	COG0741	lytic transglycosylase activity
MKR81_13665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MKR81_13670	COG0077	Prephenate dehydratase
MKR81_13670	COG1605	Chorismate mutase
MKR81_13675	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
MKR81_13690	COG0488	(ABC) transporter
MKR81_13700	COG0739	heme binding
MKR81_13705	COG0287	Prephenate dehydrogenase
MKR81_13705	COG1605	Chorismate mutase
MKR81_13710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MKR81_13720	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MKR81_13740	COG1966	Carbon starvation protein
MKR81_13745	COG3275	phosphorelay sensor kinase activity
MKR81_13750	COG3279	Response regulator of the LytR AlgR family
MKR81_13755	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MKR81_13760	COG1047	Peptidyl-prolyl cis-trans
MKR81_13775	COG0196	riboflavin kinase activity
MKR81_13780	COG0728	peptidoglycan biosynthetic process
MKR81_13785	COG0268	Binds directly to 16S ribosomal RNA
MKR81_13790	COG0640	Transcriptional regulator
MKR81_13795	COG0583	DNA-binding transcription factor activity
MKR81_13800	COG1283	sodium-dependent phosphate transmembrane transporter activity
MKR81_13815	COG0730	response to heat
MKR81_13840	COG0667	Aldo Keto reductase
MKR81_13865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MKR81_13870	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MKR81_13875	COG4974	Belongs to the 'phage' integrase family
MKR81_13880	COG0716	FMN binding
MKR81_13895	COG0513	Belongs to the DEAD box helicase family
MKR81_13905	COG3022	response to hydroperoxide
MKR81_13945	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MKR81_13950	COG0083	homoserine kinase activity
MKR81_13965	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MKR81_13975	COG0745	RESPONSE REGULATOR receiver
MKR81_13985	COG0784	Response regulator, receiver
MKR81_13985	COG2198	Histidine kinase
MKR81_13985	COG5002	protein histidine kinase activity
MKR81_13990	COG3706	GGDEF domain
MKR81_13990	COG2203	Gaf domain
MKR81_13990	COG4251	negative regulation of phosphorylation
MKR81_13990	COG5001	Diguanylate cyclase
MKR81_13995	COG1242	4 iron, 4 sulfur cluster binding
MKR81_14000	COG0067	glutamate synthase
MKR81_14000	COG0070	glutamate synthase
MKR81_14000	COG0069	glutamate synthase activity
MKR81_14010	COG0067	glutamate synthase
MKR81_14010	COG0069	glutamate synthase activity
MKR81_14010	COG0070	glutamate synthase
MKR81_14015	COG0493	'glutamate synthase
MKR81_14040	COG2860	membrane
MKR81_14045	COG0583	DNA-binding transcription factor activity
MKR81_14050	COG0730	response to heat
MKR81_14065	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MKR81_14070	COG0505	Belongs to the CarA family
MKR81_14080	COG0494	nUDIX hydrolase
MKR81_14100	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MKR81_14105	COG0849	cell division
MKR81_14110	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MKR81_14125	COG0772	Belongs to the SEDS family
MKR81_14140	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MKR81_14145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MKR81_14150	COG0768	penicillin binding
MKR81_14155	COG3116	cell division
MKR81_14170	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MKR81_14185	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MKR81_14190	COG2823	Periplasmic or secreted lipoprotein
MKR81_14195	COG2969	positive regulation of protein catabolic process
MKR81_14200	COG0625	glutathione transferase activity
MKR81_14205	COG2857	Cytochrome c1
MKR81_14210	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MKR81_14215	COG0723	plastoquinol--plastocyanin reductase activity
MKR81_14230	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MKR81_14235	COG3105	Protein conserved in bacteria
MKR81_14240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKR81_14245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKR81_14250	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKR81_14260	COG3150	esterase
MKR81_14270	COG3151	Protein conserved in bacteria
MKR81_14275	COG0494	nUDIX hydrolase
MKR81_14280	COG1538	Outer membrane efflux protein
MKR81_14290	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MKR81_14300	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MKR81_14305	COG3025	triphosphatase activity
MKR81_14310	COG1392	Phosphate transport regulator
MKR81_14315	COG0306	phosphate transporter
MKR81_14320	COG4991	sh3 domain protein
MKR81_14325	COG0405	Gamma-glutamyltransferase
MKR81_14335	COG3409	Peptidoglycan-binding domain 1 protein
MKR81_14335	COG3267	Type II secretory pathway component ExeA
MKR81_14350	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MKR81_14355	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MKR81_14365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MKR81_14370	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MKR81_14375	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MKR81_14380	COG1610	YqeY-like protein
MKR81_14385	COG0358	DNA primase activity
MKR81_14425	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKR81_14425	COG2213	PTS system mannitol-specific
MKR81_14435	COG3722	fumarate hydratase activity
MKR81_14440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MKR81_14450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MKR81_14455	COG1349	DNA-binding transcription factor activity
MKR81_14460	COG0469	pyruvate kinase activity
MKR81_14470	COG3706	GGDEF domain
MKR81_14475	COG0440	acetolactate synthase activity
MKR81_14480	COG0028	Belongs to the TPP enzyme family
MKR81_14485	COG1022	Amp-dependent synthetase and ligase
MKR81_14490	COG0583	DNA-binding transcription factor activity
MKR81_14515	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MKR81_14520	COG0473	3-isopropylmalate dehydrogenase activity
MKR81_14540	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MKR81_14545	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MKR81_14550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MKR81_14555	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MKR81_14580	COG3610	response to peptide
MKR81_14585	COG2966	Psort location CytoplasmicMembrane, score
MKR81_14600	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MKR81_14605	COG0142	geranyltranstransferase activity
MKR81_14625	COG2358	TRAP transporter, solute receptor (TAXI family
MKR81_14640	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
MKR81_14645	COG1178	ABC-type Fe3 transport system permease component
MKR81_14650	COG4143	(ABC) transporter
MKR81_14655	COG0163	prenyltransferase activity
MKR81_14660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MKR81_14670	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MKR81_14685	COG2105	PFAM AIG2 family protein
MKR81_14695	COG0729	surface antigen
MKR81_14700	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKR81_14710	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
MKR81_14725	COG1136	(ABC) transporter
MKR81_14745	COG0529	Catalyzes the synthesis of activated sulfate
MKR81_14750	COG0471	metal ion transport
MKR81_14750	COG3273	potassium ion transport
MKR81_14765	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MKR81_14765	COG1648	precorrin-2 dehydrogenase activity
MKR81_14770	COG0737	Belongs to the 5'-nucleotidase family
MKR81_14780	COG0513	Belongs to the DEAD box helicase family
MKR81_14785	COG2153	protein acetylation
MKR81_14800	COG0545	Peptidyl-prolyl cis-trans isomerase
MKR81_14810	COG0203	ribosomal protein L17
MKR81_14815	COG0202	RNA polymerase activity
MKR81_14825	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MKR81_14830	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MKR81_14835	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MKR81_14840	COG0201	protein transport
MKR81_14850	COG1841	ribosomal large subunit assembly
MKR81_14935	COG0088	Forms part of the polypeptide exit tunnel
MKR81_14955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKR81_14960	COG1609	Transcriptional regulator
MKR81_14980	COG1575	Belongs to the MenA family. Type 1 subfamily
MKR81_14985	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MKR81_14995	COG1494	fructose-1,6-bisphosphatase
MKR81_15025	COG0149	triose-phosphate isomerase activity
MKR81_15045	COG1215	transferase activity, transferring glycosyl groups
MKR81_15110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MKR81_15115	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MKR81_15120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MKR81_15165	COG1086	Polysaccharide biosynthesis protein
MKR81_15200	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MKR81_15205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MKR81_15210	COG1560	Kdo2-lipid A biosynthetic process
MKR81_15220	COG1519	Transferase
MKR81_15230	COG2089	acid synthase
MKR81_15240	COG1083	cytidylyl-transferase
MKR81_15245	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MKR81_15250	COG1086	Polysaccharide biosynthesis protein
MKR81_15255	COG3642	lipopolysaccharide core region biosynthetic process
MKR81_15260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MKR81_15265	COG0859	PFAM glycosyl transferase family 9
MKR81_15270	COG0463	Glycosyl transferase, family 2
MKR81_15325	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MKR81_15335	COG1560	Kdo2-lipid A biosynthetic process
MKR81_15340	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MKR81_15345	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MKR81_15350	COG1561	YicC-like family, N-terminal region
MKR81_15370	COG4608	Belongs to the ABC transporter superfamily
MKR81_15375	COG0444	Belongs to the ABC transporter superfamily
MKR81_15380	COG0747	negative chemotaxis
MKR81_15385	COG4239	(ABC) transporter, permease
MKR81_15390	COG4174	ABC transporter (Permease)
MKR81_15410	COG0811	peptide transport
MKR81_15415	COG0848	biopolymer transport protein
MKR81_15430	COG0194	GDP metabolic process
MKR81_15435	COG1758	RNA polymerase activity
MKR81_15440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MKR81_15445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKR81_15450	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MKR81_15460	COG2233	PERMEase
MKR81_15475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MKR81_15485	COG2183	response to ionizing radiation
MKR81_15500	COG1040	competence protein
MKR81_15510	COG0494	nUDIX hydrolase
MKR81_15515	COG1218	3'(2'),5'-bisphosphate nucleotidase
MKR81_15525	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
MKR81_15530	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
MKR81_15535	COG3156	type II secretion system protein K
MKR81_15540	COG4795	General secretion pathway protein
MKR81_15545	COG2165	general secretion pathway protein
MKR81_15550	COG2165	general secretion pathway protein
MKR81_15555	COG2165	general secretion pathway protein
MKR81_15560	COG1459	type II secretion system
MKR81_15565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MKR81_15575	COG3031	protein transport across the cell outer membrane
MKR81_15580	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MKR81_15600	COG0456	acetyltransferase
MKR81_15605	COG1490	D-aminoacyl-tRNA deacylase activity
MKR81_15625	COG1217	gtp-binding protein TYPA
MKR81_15630	COG0174	glutamine synthetase
MKR81_15640	COG3852	Histidine kinase
MKR81_15645	COG2204	response regulator
MKR81_15655	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MKR81_15685	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MKR81_15690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKR81_15690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKR81_15705	COG0084	hydrolase, TatD family'
MKR81_15710	COG0805	protein transport
MKR81_15715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MKR81_15730	COG3165	ubiquinone biosynthetic process from chorismate
MKR81_15740	COG1322	Protein conserved in bacteria
MKR81_15755	COG1910	domain protein
MKR81_15780	COG2081	HI0933 family
MKR81_15790	COG1528	Iron-storage protein
MKR81_15795	COG0589	response to stress
MKR81_15815	COG5001	Diguanylate cyclase
MKR81_15815	COG5002	protein histidine kinase activity
MKR81_15820	COG1522	sequence-specific DNA binding
MKR81_15830	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MKR81_15840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MKR81_15885	COG3501	Rhs element vgr protein
MKR81_15920	COG0800	Aldolase
MKR81_15925	COG2610	gluconate transmembrane transporter activity
MKR81_15930	COG3265	gluconokinase activity
MKR81_15935	COG0129	dihydroxy-acid dehydratase activity
MKR81_15945	COG2076	Multidrug Resistance protein
MKR81_15950	COG0583	DNA-binding transcription factor activity
MKR81_15955	COG1609	Transcriptional regulator
MKR81_15960	COG0515	serine threonine protein kinase
MKR81_15990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKR81_15995	COG0601	transmembrane transport
MKR81_16005	COG4172	Belongs to the ABC transporter superfamily
MKR81_16050	COG1309	transcriptional regulator
MKR81_16055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKR81_16060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MKR81_16065	COG2960	long-chain fatty acid transporting porin activity
MKR81_16070	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MKR81_16075	COG0583	DNA-binding transcription factor activity
MKR81_16115	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MKR81_16140	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MKR81_16145	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MKR81_16150	COG0551	DNA topoisomerase type I activity
MKR81_16160	COG0758	DNA mediated transformation
MKR81_16180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MKR81_16180	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MKR81_16185	COG0569	domain protein
MKR81_16190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MKR81_16200	COG1272	protein, Hemolysin III
MKR81_16205	COG4326	sporulation control protein
MKR81_16215	COG3084	Protein conserved in bacteria
MKR81_16225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MKR81_16230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MKR81_16235	COG0204	Acyl-transferase
MKR81_16245	COG2199	diguanylate cyclase activity
MKR81_16250	COG0606	chelatase, subunit chli
MKR81_16260	COG3978	acetolactate synthase activity
MKR81_16265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MKR81_16270	COG0129	dihydroxy-acid dehydratase activity
MKR81_16280	COG0583	DNA-binding transcription factor activity
MKR81_16285	COG2814	Major facilitator Superfamily
MKR81_16290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MKR81_16295	COG0765	amino acid transport
MKR81_16305	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MKR81_16315	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MKR81_16345	COG3312	ion transport
MKR81_16350	COG1475	DNA binding
MKR81_16355	COG1192	Involved in chromosome partitioning
MKR81_16370	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MKR81_16400	COG1126	abc transporter atp-binding protein
MKR81_16415	COG0581	inorganic phosphate transmembrane transporter activity
MKR81_16420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MKR81_16435	COG2304	oxidoreductase activity
MKR81_16455	COG0714	Associated with various cellular activities
MKR81_16475	COG0840	transmembrane signaling receptor activity
MKR81_16485	COG2197	response regulator
MKR81_16510	COG0110	maltose O-acetyltransferase activity
MKR81_16515	COG2204	response regulator
MKR81_16520	COG4191	Histidine kinase
MKR81_16525	COG1028	Short-chain dehydrogenase reductase Sdr
MKR81_16575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MKR81_16580	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
MKR81_16590	COG1252	NADH dehydrogenase
MKR81_16595	COG1301	dicarboxylic acid transport
MKR81_16600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MKR81_16610	COG1566	PFAM secretion protein HlyD family protein
MKR81_16640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MKR81_16640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKR81_16640	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MKR81_16645	COG2207	Transcriptional regulator
MKR81_16655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MKR81_16660	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MKR81_16670	COG2084	Dehydrogenase
MKR81_16675	COG0753	catalase activity
MKR81_16685	COG2130	NADP-dependent
MKR81_16690	COG1309	transcriptional regulator
MKR81_16735	COG0489	protein tyrosine kinase activity
MKR81_16735	COG3206	protein involved in exopolysaccharide biosynthesis
MKR81_16750	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MKR81_16755	COG2200	EAL domain
MKR81_16760	COG3842	ATPase activity
MKR81_16770	COG1175	transmembrane transport
MKR81_16775	COG3833	ABC-type maltose transport systems, permease component
MKR81_16805	COG2354	Protein conserved in bacteria
MKR81_16815	COG0401	homolog of Blt101
MKR81_16820	COG0633	Ferredoxin
MKR81_16820	COG3217	Mosc domain protein beta barrel domain protein
MKR81_16820	COG0633	Ferredoxin
MKR81_16820	COG3217	Mosc domain protein beta barrel domain protein
MKR81_16830	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MKR81_16870	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
MKR81_16875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKR81_16885	COG0848	biopolymer transport protein
MKR81_16890	COG0811	peptide transport
MKR81_16895	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MKR81_16905	COG3721	Heme iron utilization protein
MKR81_16910	COG0748	coenzyme F420 binding
MKR81_16925	COG0835	chemotaxis
MKR81_16925	COG0784	Response regulator, receiver
MKR81_16930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MKR81_16935	COG0366	Alpha amylase catalytic
MKR81_16975	COG0583	DNA-binding transcription factor activity
MKR81_16995	COG0583	DNA-binding transcription factor activity
MKR81_17015	COG2814	Major facilitator Superfamily
MKR81_17025	COG4977	sequence-specific DNA binding
MKR81_17030	COG0673	inositol 2-dehydrogenase activity
MKR81_17035	COG2194	sulfuric ester hydrolase activity
MKR81_17040	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MKR81_17050	COG2205	protein histidine kinase activity
MKR81_17055	COG0745	RESPONSE REGULATOR receiver
MKR81_17065	COG4221	oxidoreductase activity
MKR81_17080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MKR81_17100	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MKR81_17125	COG1418	mRNA catabolic process
MKR81_17140	COG0402	S-adenosylhomocysteine deaminase activity
MKR81_17145	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MKR81_17150	COG2239	Acts as a magnesium transporter
MKR81_17155	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MKR81_17160	COG1566	PFAM secretion protein HlyD family protein
MKR81_17185	COG0745	RESPONSE REGULATOR receiver
MKR81_17190	COG2205	protein histidine kinase activity
MKR81_17200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MKR81_17205	COG0531	amino acid
MKR81_17220	COG0583	DNA-binding transcription factor activity
MKR81_17245	COG0784	Response regulator, receiver
MKR81_17245	COG2205	protein histidine kinase activity
MKR81_17245	COG5002	protein histidine kinase activity
MKR81_17250	COG0673	inositol 2-dehydrogenase activity
MKR81_17325	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MKR81_17330	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MKR81_17340	COG1280	lysine exporter protein (LysE YggA)
MKR81_17350	COG0183	Belongs to the thiolase family
MKR81_17370	COG3005	denitrification pathway
MKR81_17390	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MKR81_17395	COG3850	Histidine kinase
MKR81_17400	COG2197	response regulator
MKR81_17415	COG2195	Cleaves the N-terminal amino acid of tripeptides
MKR81_17435	COG0840	transmembrane signaling receptor activity
MKR81_17445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MKR81_17450	COG0545	Peptidyl-prolyl cis-trans isomerase
MKR81_17480	COG1278	Cold shock
MKR81_17485	COG3036	rescue of stalled ribosome
MKR81_17515	COG0577	efflux transmembrane transporter activity
MKR81_17515	COG1136	(ABC) transporter
MKR81_17525	COG0840	transmembrane signaling receptor activity
MKR81_17530	COG0783	Belongs to the Dps family
MKR81_17540	COG1619	proteins homologs of microcin C7 resistance protein MccF
MKR81_17545	COG2133	pyrroloquinoline quinone binding
MKR81_17550	COG1454	alcohol dehydrogenase
MKR81_17555	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
MKR81_17580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MKR81_17590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MKR81_17595	COG3186	Phenylalanine-4-hydroxylase
MKR81_17625	COG3530	Putative quorum-sensing-regulated virulence factor
MKR81_17655	COG0523	cobalamin synthesis protein
MKR81_17660	COG3447	MASE1 domain protein
MKR81_17660	COG5001	Diguanylate cyclase
MKR81_17660	COG5002	protein histidine kinase activity
MKR81_17665	COG0513	Belongs to the DEAD box helicase family
MKR81_17685	COG2200	EAL domain
MKR81_17690	COG1119	ATPase activity
MKR81_17745	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MKR81_17760	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
MKR81_17765	COG0513	Belongs to the DEAD box helicase family
MKR81_17855	COG1609	Transcriptional regulator
MKR81_17865	COG2182	Extracellular solute-binding protein
MKR81_17875	COG3833	ABC-type maltose transport systems, permease component
MKR81_17885	COG1874	Beta-galactosidase
MKR81_17890	COG4580	involved in the transport of maltose and maltodextrins
MKR81_17895	COG0840	transmembrane signaling receptor activity
MKR81_17900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MKR81_17955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MKR81_17960	COG3550	peptidyl-serine autophosphorylation
MKR81_17970	COG2814	Major facilitator Superfamily
MKR81_17975	COG0583	DNA-binding transcription factor activity
MKR81_17995	COG1902	pentaerythritol trinitrate reductase activity
MKR81_18000	COG1902	pentaerythritol trinitrate reductase activity
MKR81_18010	COG1733	regulation of RNA biosynthetic process
MKR81_18055	COG3278	Belongs to the heme-copper respiratory oxidase family
MKR81_18100	COG1024	Enoyl-CoA hydratase
MKR81_18105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MKR81_18110	COG1960	acyl-CoA dehydrogenase activity
MKR81_18120	COG0183	Belongs to the thiolase family
MKR81_18135	COG1024	Enoyl-CoA hydratase
MKR81_18140	COG1024	Enoyl-CoA hydratase
MKR81_18150	COG1028	Short-chain dehydrogenase reductase Sdr
MKR81_18155	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MKR81_18160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MKR81_18165	COG1845	cytochrome c oxidase, subunit III
MKR81_18170	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MKR81_18185	COG1902	pentaerythritol trinitrate reductase activity
MKR81_18185	COG0446	pyridine nucleotide-disulphide oxidoreductase
MKR81_18200	COG1012	belongs to the aldehyde dehydrogenase family
MKR81_18210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MKR81_18265	COG1126	abc transporter atp-binding protein
MKR81_18270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MKR81_18275	COG4215	(ABC) transporter
MKR81_18280	COG4160	amino acid transport
MKR81_18290	COG0583	DNA-binding transcription factor activity
MKR81_18305	COG2200	EAL domain
MKR81_18350	COG0443	Heat shock 70 kDa protein
MKR81_18390	COG0745	RESPONSE REGULATOR receiver
MKR81_18405	COG1785	Belongs to the alkaline phosphatase family
MKR81_18430	COG0814	amino acid
MKR81_18435	COG5002	protein histidine kinase activity
MKR81_18435	COG5001	Diguanylate cyclase
MKR81_18445	COG0243	molybdopterin cofactor binding
MKR81_18465	COG3707	response regulator
MKR81_18470	COG1116	anion transmembrane transporter activity
MKR81_18470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MKR81_18475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MKR81_18480	COG1116	anion transmembrane transporter activity
MKR81_18485	COG2146	nitrite reductase [NAD(P)H] activity
MKR81_18485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MKR81_18520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MKR81_18540	COG0739	heme binding
MKR81_18550	COG3038	cytochrome b561
MKR81_18660	COG2814	Major facilitator Superfamily
MKR81_18680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MKR81_18685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MKR81_18695	COG1132	(ABC) transporter
MKR81_18705	COG5640	endopeptidase activity
MKR81_18725	COG0583	DNA-binding transcription factor activity
MKR81_18760	COG1120	ATPase activity
MKR81_18765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKR81_18770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKR81_18775	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MKR81_18800	COG4977	sequence-specific DNA binding
MKR81_18815	COG3547	Transposase (IS116 IS110 IS902 family)
MKR81_18890	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MKR81_18900	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MKR81_18910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKR81_18915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKR81_18930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MKR81_18930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MKR81_18930	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
MKR81_18935	COG1105	Belongs to the carbohydrate kinase PfkB family
MKR81_18940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKR81_18940	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKR81_18945	COG1609	Transcriptional regulator
MKR81_18960	COG2199	diguanylate cyclase activity
MKR81_18960	COG2200	EAL domain
MKR81_18960	COG2203	Gaf domain
MKR81_18965	COG0765	amino acid transport
MKR81_18970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MKR81_18975	COG0765	amino acid transport
MKR81_18980	COG1126	abc transporter atp-binding protein
MKR81_18990	COG1979	alcohol dehydrogenase
MKR81_18995	COG2207	Transcriptional regulator
MKR81_19005	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MKR81_19015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKR81_19030	COG3437	response regulator, receiver
MKR81_19030	COG0784	Response regulator, receiver
MKR81_19035	COG0546	phosphoglycolate phosphatase activity
MKR81_19040	COG0840	transmembrane signaling receptor activity
MKR81_19045	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
MKR81_19050	COG0513	Belongs to the DEAD box helicase family
MKR81_19055	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MKR81_19070	COG3038	cytochrome b561
MKR81_19080	COG2116	formate transmembrane transporter activity
MKR81_19085	COG0583	DNA-binding transcription factor activity
MKR81_19095	COG3593	DNA synthesis involved in DNA repair
MKR81_19100	COG0737	Belongs to the 5'-nucleotidase family
MKR81_19115	COG0646	methionine synthase
MKR81_19115	COG1410	methionine synthase
MKR81_19130	COG2267	carboxylic ester hydrolase activity
MKR81_19135	COG2067	long-chain fatty acid transport protein
MKR81_19145	COG0501	Belongs to the peptidase M48B family
MKR81_19150	COG2050	protein possibly involved in aromatic compounds catabolism
MKR81_19195	COG3300	MHYT domain
MKR81_19195	COG5001	Diguanylate cyclase
MKR81_19200	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MKR81_19210	COG4181	ATPase activity
MKR81_19215	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MKR81_19225	COG1984	allophanate hydrolase subunit 2
MKR81_19230	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MKR81_19240	COG5002	protein histidine kinase activity
MKR81_19240	COG3447	MASE1 domain protein
MKR81_19240	COG5001	Diguanylate cyclase
MKR81_19245	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MKR81_19255	COG0583	DNA-binding transcription factor activity
MKR81_19260	COG0045	succinate-CoA ligase (ADP-forming) activity
MKR81_19260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKR81_19260	COG1042	CoA-binding domain protein
MKR81_19280	COG0023	Translation Initiation Factor
MKR81_19295	COG3140	Belongs to the UPF0181 family
MKR81_19320	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MKR81_19325	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MKR81_19345	COG5001	Diguanylate cyclase
MKR81_19345	COG3706	GGDEF domain
MKR81_19345	COG4251	negative regulation of phosphorylation
MKR81_19345	COG2203	Gaf domain
MKR81_19355	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MKR81_19360	COG4149	molybdate abc transporter
MKR81_19365	COG0725	ABC transporter, periplasmic molybdate-binding protein
MKR81_19375	COG3111	PFAM Bacterial OB fold (BOF) protein
MKR81_19400	COG0534	Mate efflux family protein
MKR81_19405	COG0602	queuosine metabolic process
MKR81_19410	COG1328	CTP reductase activity
MKR81_19470	COG2197	response regulator
MKR81_19475	COG3851	Histidine kinase
MKR81_19480	COG2271	Major facilitator Superfamily
MKR81_19485	COG1482	cell wall glycoprotein biosynthetic process
MKR81_19495	COG0628	permease
MKR81_19505	COG1566	PFAM secretion protein HlyD family protein
MKR81_19530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKR81_19535	COG3118	belongs to the thioredoxin family
MKR81_19565	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MKR81_19585	COG2116	formate transmembrane transporter activity
MKR81_19595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MKR81_19605	COG2199	diguanylate cyclase activity
MKR81_19690	COG0277	FAD linked oxidase domain protein
MKR81_19695	COG0583	DNA-binding transcription factor activity
MKR81_19710	COG2425	protein containing a von Willebrand factor type A (vWA) domain
MKR81_19725	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
MKR81_19735	COG1288	antiporter activity
MKR81_19745	COG2814	Major facilitator Superfamily
MKR81_19755	COG3040	lipid binding
MKR81_19785	COG3469	chitinase activity
MKR81_19795	COG0419	ATPase involved in DNA repair
MKR81_19800	COG0420	3'-5' exonuclease activity
MKR81_19810	COG3209	COG3209 Rhs family protein
MKR81_19880	COG0631	protein serine/threonine phosphatase activity
MKR81_19915	COG2815	serine threonine protein kinase
MKR81_19915	COG0515	serine threonine protein kinase
MKR81_19945	COG0346	lactoylglutathione lyase activity
MKR81_19950	COG1902	pentaerythritol trinitrate reductase activity
MKR81_19960	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MKR81_19960	COG2755	lipolytic protein G-D-S-L family
MKR81_19970	COG5642	Protein of unknown function (DUF2384)
MKR81_19985	COG1234	tRNA 3'-trailer cleavage
MKR81_19990	COG2067	long-chain fatty acid transport protein
MKR81_20040	COG0671	phosphoesterase, PA-phosphatase related
MKR81_20055	COG2962	Rard protein
MKR81_20065	COG2165	general secretion pathway protein
MKR81_20070	COG0784	Response regulator, receiver
MKR81_20070	COG0835	chemotaxis
MKR81_20075	COG0778	Nitroreductase
MKR81_20080	COG2197	response regulator
MKR81_20090	COG3706	GGDEF domain
MKR81_20095	COG2197	response regulator
MKR81_20100	COG5001	Diguanylate cyclase
MKR81_20100	COG3300	MHYT domain
MKR81_20105	COG0784	Response regulator, receiver
MKR81_20105	COG2205	protein histidine kinase activity
MKR81_20120	COG4771	TonB-dependent receptor
MKR81_20235	COG1522	sequence-specific DNA binding
MKR81_20270	COG0515	serine threonine protein kinase
MKR81_20295	COG3501	Rhs element vgr protein
MKR81_20310	COG2204	response regulator
MKR81_20340	COG0739	heme binding
MKR81_20345	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MKR81_20375	COG3069	C4-dicarboxylate transmembrane transporter activity
MKR81_20380	COG1704	LemA family
MKR81_20385	COG0501	Belongs to the peptidase M48B family
MKR81_20410	COG0641	radical SAM
MKR81_20430	COG3111	PFAM Bacterial OB fold (BOF) protein
MKR81_20435	COG1597	lipid kinase activity
MKR81_20440	COG0583	DNA-binding transcription factor activity
MKR81_20455	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MKR81_20465	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MKR81_20525	COG0714	Associated with various cellular activities
MKR81_20535	COG3119	arylsulfatase activity
MKR81_20540	COG3119	arylsulfatase activity
MKR81_20570	COG0784	Response regulator, receiver
MKR81_20570	COG2205	protein histidine kinase activity
MKR81_20570	COG2198	Histidine kinase
MKR81_20575	COG1879	ABC-type sugar transport system periplasmic component
MKR81_20585	COG0210	DNA helicase
MKR81_20590	COG1289	transmembrane transporter activity
MKR81_20620	COG0789	Transcriptional regulator
MKR81_20625	COG4604	ABC transporter, ATP-binding protein
MKR81_20630	COG4605	iron ion homeostasis
MKR81_20635	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKR81_20640	COG4607	ABC-type enterochelin transport system periplasmic component
MKR81_20655	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
MKR81_20670	COG1609	Transcriptional regulator
MKR81_20675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKR81_20680	COG1879	ABC-type sugar transport system periplasmic component
MKR81_20685	COG1172	Belongs to the binding-protein-dependent transport system permease family
MKR81_20690	COG1129	ABC transporter
MKR81_20700	COG5001	Diguanylate cyclase
MKR81_20705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MKR81_20710	COG1794	racemase activity, acting on amino acids and derivatives
MKR81_20735	COG0586	Pfam SNARE associated Golgi protein
MKR81_20775	COG2205	protein histidine kinase activity
MKR81_20775	COG0784	Response regulator, receiver
MKR81_20805	COG0330	HflC and HflK could
MKR81_20815	COG0517	IMP dehydrogenase activity
MKR81_20815	COG4175	Glycine betaine
MKR81_20820	COG4176	ABC-type proline glycine betaine transport system permease component
MKR81_20855	COG0402	S-adenosylhomocysteine deaminase activity
MKR81_20875	COG2885	chlorophyll binding
MKR81_20915	COG0455	bacterial-type flagellum organization
MKR81_20925	COG4964	Belongs to the GSP D family
MKR81_20945	COG0583	DNA-binding transcription factor activity
MKR81_20950	COG1073	alpha beta
MKR81_20970	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MKR81_20970	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MKR81_20985	COG4989	oxidoreductase activity
MKR81_21010	COG1914	H( )-stimulated, divalent metal cation uptake system
MKR81_21025	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MKR81_21085	COG2897	thiosulfate sulfurtransferase activity
MKR81_21110	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MKR81_21115	COG0840	transmembrane signaling receptor activity
MKR81_21120	COG2814	Major facilitator Superfamily
MKR81_21125	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MKR81_21140	COG1612	heme a metabolic process
MKR81_21165	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
MKR81_21170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MKR81_21180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MKR81_21190	COG1280	lysine exporter protein (LysE YggA)
MKR81_21210	COG0179	Fumarylacetoacetate (FAA) hydrolase
MKR81_21225	COG0697	spore germination
MKR81_21240	COG2814	Major facilitator Superfamily
MKR81_21245	COG0583	DNA-binding transcription factor activity
MKR81_21250	COG5001	Diguanylate cyclase
MKR81_21255	COG0739	heme binding
MKR81_21275	COG3314	Sporulation integral membrane protein YlbJ
MKR81_21290	COG0814	amino acid
MKR81_21310	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MKR81_21315	COG1072	(Pantothenic acid kinase))
MKR81_21325	COG1063	alcohol dehydrogenase
MKR81_21330	COG2213	PTS system mannitol-specific
MKR81_21335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKR81_21350	COG1733	regulation of RNA biosynthetic process
MKR81_21365	COG0798	PFAM Bile acid sodium symporter
MKR81_21380	COG1881	PFAM PEBP family protein
MKR81_21390	COG0251	oxidation-reduction process
MKR81_21395	COG2706	6-phosphogluconolactonase activity
MKR81_21405	COG0800	Aldolase
MKR81_21410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKR81_21415	COG4145	pantothenate transmembrane transporter activity
MKR81_21425	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MKR81_21450	COG1131	(ABC) transporter
MKR81_21455	COG0842	Transport permease protein
MKR81_21475	COG3383	formate dehydrogenase (NAD+) activity
MKR81_21495	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MKR81_21540	COG0494	nUDIX hydrolase
MKR81_21555	COG1858	cytochrome C peroxidase
MKR81_21565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKR81_21570	COG2067	long-chain fatty acid transport protein
MKR81_21575	COG1505	serine-type exopeptidase activity
MKR81_21580	COG0488	(ABC) transporter
MKR81_21590	COG0589	response to stress
MKR81_21600	COG0584	glycerophosphoryl diester phosphodiesterase
MKR81_21610	COG1175	transmembrane transport
MKR81_21615	COG0395	ABC-type sugar transport system, permease component
MKR81_21620	COG3842	ATPase activity
MKR81_21635	COG0523	cobalamin synthesis protein
MKR81_21645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MKR81_21655	COG4667	esterase of the alpha-beta hydrolase superfamily
MKR81_21660	COG1741	Belongs to the pirin family
MKR81_21665	COG1278	Cold shock
MKR81_21680	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MKR81_21710	COG2226	methyltransferase
MKR81_21720	COG1686	Belongs to the peptidase S11 family
MKR81_21725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MKR81_21730	COG0625	glutathione transferase activity
MKR81_21740	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MKR81_21780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKR81_21790	COG1940	carbohydrate kinase activity
MKR81_21795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MKR81_21800	COG1737	Transcriptional regulator
MKR81_21815	COG0698	ribose 5-phosphate isomerase
MKR81_21820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MKR81_21830	COG1028	Short-chain dehydrogenase reductase Sdr
MKR81_21855	COG3746	phosphate-selective porin O and P
MKR81_21880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MKR81_21925	COG0513	Belongs to the DEAD box helicase family
MKR81_21930	COG0515	serine threonine protein kinase
MKR81_21930	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MKR81_21955	COG0583	DNA-binding transcription factor activity
MKR81_21975	COG1028	Short-chain dehydrogenase reductase Sdr
MKR81_21985	COG1902	pentaerythritol trinitrate reductase activity
MKR81_21995	COG3853	Toxic anion resistance protein (TelA)
MKR81_22005	COG2255	four-way junction helicase activity
MKR81_22015	COG3122	Protein conserved in bacteria
MKR81_22020	COG2321	neutral zinc metallopeptidase
MKR81_22035	COG0583	DNA-binding transcription factor activity
MKR81_22040	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MKR81_22055	COG0252	asparaginase activity
MKR81_22065	COG0574	Belongs to the PEP-utilizing enzyme family
MKR81_22065	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MKR81_22075	COG2197	response regulator
MKR81_22080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MKR81_22095	COG0583	DNA-binding transcription factor activity
MKR81_22100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKR81_22110	COG1538	Outer membrane efflux protein
MKR81_22120	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MKR81_22125	COG0786	glutamate:sodium symporter activity
MKR81_22155	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MKR81_22160	COG0318	PFAM AMP-dependent synthetase and ligase
MKR81_22230	COG4964	Belongs to the GSP D family
MKR81_22285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MKR81_22295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKR81_22335	COG4948	Mandelate Racemase Muconate Lactonizing
MKR81_22360	COG1342	Belongs to the UPF0251 family
MKR81_22370	COG4176	ABC-type proline glycine betaine transport system permease component
MKR81_22375	COG3448	diguanylate cyclase activity
MKR81_22375	COG4175	Glycine betaine
MKR81_22395	COG0589	response to stress
MKR81_22400	COG0583	DNA-binding transcription factor activity
MKR81_22410	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
MKR81_22440	COG1335	isochorismatase
MKR81_22455	COG0753	catalase activity
MKR81_22470	COG1349	DNA-binding transcription factor activity
MKR81_22475	COG0346	lactoylglutathione lyase activity
MKR81_22480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKR81_22480	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKR81_22490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MKR81_22495	COG3537	Alpha-1,2-mannosidase
MKR81_22500	COG3537	Alpha-1,2-mannosidase
MKR81_22510	COG3537	Alpha-1,2-mannosidase
MKR81_22515	COG3537	Alpha-1,2-mannosidase
MKR81_22525	COG1280	lysine exporter protein (LysE YggA)
MKR81_22530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MKR81_22545	COG4628	conserved protein (DUF2132)
MKR81_22550	COG0488	(ABC) transporter
MKR81_22565	COG0346	lactoylglutathione lyase activity
MKR81_22570	COG0384	phenazine biosynthesis protein PhzF
MKR81_22585	COG3220	belongs to the UPF0276 family
MKR81_22600	COG1271	oxidase subunit
MKR81_22605	COG1294	oxidase, subunit
MKR81_22645	COG1882	Formate acetyltransferase
MKR81_22650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MKR81_22655	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MKR81_22670	COG2205	protein histidine kinase activity
MKR81_22675	COG0745	RESPONSE REGULATOR receiver
MKR81_22685	COG0454	-acetyltransferase
MKR81_22690	COG0148	phosphopyruvate hydratase activity
MKR81_22700	COG2814	Major facilitator Superfamily
MKR81_22715	COG0583	DNA-binding transcription factor activity
MKR81_22720	COG2988	succinylglutamate desuccinylase activity
MKR81_22760	COG0628	permease
MKR81_22765	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
MKR81_22780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MKR81_22790	COG4628	conserved protein (DUF2132)
MKR81_22795	COG0583	DNA-binding transcription factor activity
MKR81_22805	COG1686	Belongs to the peptidase S11 family
MKR81_22830	COG0415	Belongs to the DNA photolyase family
MKR81_22835	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MKR81_22845	COG4667	esterase of the alpha-beta hydrolase superfamily
MKR81_22850	COG2095	MarC family integral membrane protein
MKR81_22865	COG1596	polysaccharide export
MKR81_22870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MKR81_22905	COG1301	dicarboxylic acid transport
MKR81_22915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MKR81_22920	COG0700	Nucleoside recognition
MKR81_22925	COG3366	ferrous iron transmembrane transporter activity
MKR81_22940	COG0366	Alpha amylase catalytic
MKR81_22945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MKR81_22950	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MKR81_22955	COG1640	4-alpha-glucanotransferase
MKR81_22960	COG0058	SHG alpha-glucan phosphorylase activity
MKR81_22980	COG1999	signal sequence binding
MKR81_23000	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MKR81_23020	COG0531	amino acid
MKR81_23025	COG1982	Orn Lys Arg decarboxylase major
MKR81_23045	COG2356	endonuclease I
MKR81_23050	COG0366	Alpha amylase catalytic
MKR81_23070	COG4580	involved in the transport of maltose and maltodextrins
MKR81_23080	COG2199	diguanylate cyclase activity
MKR81_23080	COG2203	Gaf domain
MKR81_23110	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MKR81_23120	COG1760	l-serine dehydratase
MKR81_23145	COG1609	Transcriptional regulator
MKR81_23155	COG2814	Major facilitator Superfamily
MKR81_23170	COG0739	heme binding
MKR81_23185	COG0800	Aldolase
MKR81_23190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKR81_23195	COG1263	PTS System
MKR81_23195	COG2190	(PTS) system
MKR81_23195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKR81_23205	COG2188	Transcriptional regulator
MKR81_23230	COG3121	Chaperone
MKR81_23235	COG3188	usher protein
MKR81_23270	COG0612	Peptidase, M16
MKR81_23275	COG0840	transmembrane signaling receptor activity
MKR81_23285	COG0826	peptidase U32
MKR81_23315	COG0463	Glycosyl transferase, family 2
MKR81_23335	COG1335	isochorismatase
MKR81_23340	COG1136	(ABC) transporter
MKR81_23345	COG0577	efflux transmembrane transporter activity
MKR81_23395	COG1764	response to oxidative stress
MKR81_23400	COG1846	Transcriptional regulator
MKR81_23410	COG3634	alkyl hydroperoxide reductase activity
MKR81_23430	COG2610	gluconate transmembrane transporter activity
MKR81_23435	COG3622	Belongs to the hyi family
MKR81_23440	COG0235	Class ii aldolase
MKR81_23445	COG3395	kinase activity
MKR81_23450	COG2084	Dehydrogenase
MKR81_23455	COG1349	DNA-binding transcription factor activity
MKR81_23460	COG0583	DNA-binding transcription factor activity
MKR81_23465	COG0366	Alpha amylase catalytic
MKR81_23510	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
MKR81_23520	COG1522	sequence-specific DNA binding
MKR81_23525	COG0544	peptidyl-prolyl cis-trans isomerase activity
MKR81_23530	COG0544	peptidyl-prolyl cis-trans isomerase activity
MKR81_23545	COG2258	MOSC domain
MKR81_23550	COG2153	protein acetylation
MKR81_23565	COG1757	Na H antiporter
MKR81_23570	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MKR81_23575	COG0513	Belongs to the DEAD box helicase family
MKR81_23580	COG1595	DNA-templated transcription, initiation
MKR81_23590	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MKR81_23595	COG1312	Catalyzes the dehydration of D-mannonate
MKR81_23600	COG2186	Transcriptional regulator
MKR81_23610	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MKR81_23620	COG0246	Mannitol dehydrogenase
MKR81_23625	COG1904	glucuronate isomerase
MKR81_23630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKR81_23635	COG0800	Aldolase
MKR81_23675	COG1132	(ABC) transporter
MKR81_23795	COG4166	transmembrane transport
MKR81_23810	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MKR81_23815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKR81_23815	COG1263	PTS System
MKR81_23820	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MKR81_23845	COG1444	tRNA N-acetyltransferase activity
MKR81_23870	COG4608	Belongs to the ABC transporter superfamily
MKR81_23875	COG0444	Belongs to the ABC transporter superfamily
MKR81_23885	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MKR81_23885	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
MKR81_23910	COG0772	Belongs to the SEDS family
MKR81_23920	COG1566	PFAM secretion protein HlyD family protein
MKR81_23925	COG0583	DNA-binding transcription factor activity
MKR81_23935	COG1136	(ABC) transporter
MKR81_23955	COG3275	phosphorelay sensor kinase activity
MKR81_23960	COG3279	Response regulator of the LytR AlgR family
MKR81_23970	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MKR81_23990	COG0786	glutamate:sodium symporter activity
MKR81_24030	COG1131	(ABC) transporter
MKR81_24035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MKR81_24040	COG0786	glutamate:sodium symporter activity
MKR81_24070	COG2259	Doxx family
MKR81_24080	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MKR81_24085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MKR81_24095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKR81_24140	COG2199	diguanylate cyclase activity
MKR81_24140	COG2200	EAL domain
MKR81_24140	COG2202	Pas domain
MKR81_24175	COG2885	chlorophyll binding
MKR81_24180	COG1858	cytochrome C peroxidase
MKR81_24185	COG0745	RESPONSE REGULATOR receiver
MKR81_24200	COG0642	Histidine kinase
MKR81_24220	COG5001	Diguanylate cyclase
MKR81_24235	COG1609	Transcriptional regulator
MKR81_24250	COG0395	ABC-type sugar transport system, permease component
MKR81_24255	COG2723	6-phospho-beta-galactosidase activity
MKR81_24260	COG3842	ATPase activity
MKR81_24265	COG1609	Transcriptional regulator
MKR81_24275	COG0747	negative chemotaxis
MKR81_24285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKR81_24290	COG0444	Belongs to the ABC transporter superfamily
MKR81_24295	COG4608	Belongs to the ABC transporter superfamily
MKR81_24305	COG1609	Transcriptional regulator
MKR81_24325	COG1472	Belongs to the glycosyl hydrolase 3 family
MKR81_24330	COG0534	Mate efflux family protein
MKR81_24335	COG0564	pseudouridine synthase activity
MKR81_24340	COG0561	phosphatase activity
MKR81_24360	COG3152	Membrane
MKR81_24375	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MKR81_24400	COG0583	DNA-binding transcription factor activity
MKR81_24415	COG2270	Major facilitator Superfamily
MKR81_24450	COG2076	Multidrug Resistance protein
MKR81_24465	COG0534	Mate efflux family protein
MKR81_24480	COG1357	PFAM Pentapeptide repeats (8 copies)
MKR81_24485	COG3047	cAMP biosynthetic process
MKR81_24495	COG2814	Major facilitator Superfamily
MKR81_24515	COG3408	Glycogen debranching enzyme
MKR81_24515	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
MKR81_24605	COG3835	regulator
MKR81_24610	COG1929	Belongs to the glycerate kinase type-1 family
MKR81_24615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MKR81_24655	COG0456	acetyltransferase
MKR81_24675	COG1028	Short-chain dehydrogenase reductase Sdr
MKR81_24685	COG3005	denitrification pathway
MKR81_24690	COG0243	molybdopterin cofactor binding
MKR81_24695	COG0671	phosphoesterase, PA-phosphatase related
MKR81_24710	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MKR81_24715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MKR81_24720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MKR81_24725	COG1116	anion transmembrane transporter activity
MKR81_24730	COG0351	phosphomethylpyrimidine kinase
MKR81_24735	COG0312	modulator of DNA gyrase
MKR81_24740	COG0312	modulator of DNA gyrase
MKR81_24800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKR81_24810	COG0584	glycerophosphoryl diester phosphodiesterase
MKR81_24815	COG0745	RESPONSE REGULATOR receiver
MKR81_24835	COG0811	peptide transport
MKR81_24840	COG0811	peptide transport
MKR81_24845	COG0848	biopolymer transport protein
MKR81_24890	COG0803	Belongs to the bacterial solute-binding protein 9 family
MKR81_24895	COG1121	(ABC) transporter
MKR81_24900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MKR81_24915	COG1770	oligopeptidase
MKR81_24920	COG2814	Major facilitator Superfamily
MKR81_24925	COG0010	Belongs to the arginase family
MKR81_24930	COG1166	arginine decarboxylase activity
MKR81_24940	COG0189	ligase activity
MKR81_24940	COG4067	protein conserved in archaea
MKR81_24945	COG0189	ligase activity
MKR81_24950	COG0583	DNA-binding transcription factor activity
MKR81_24995	COG1114	Component of the transport system for branched-chain amino acids
MKR81_25010	COG0579	oxidoreductase
MKR81_25015	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MKR81_25030	COG3033	Beta-eliminating lyase
MKR81_25045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKR81_25050	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MKR81_25085	COG3706	GGDEF domain
MKR81_25090	COG0415	Belongs to the DNA photolyase family
MKR81_25095	COG3046	protein related to deoxyribodipyrimidine photolyase
MKR81_25110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKR81_25110	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKR81_25115	COG1765	OsmC-like protein
MKR81_25150	COG1011	Hydrolase
MKR81_25175	COG3240	lipase activity
MKR81_25195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKR81_25205	COG1840	ABC-type Fe3 transport system, periplasmic component
MKR81_25210	COG3842	ATPase activity
MKR81_25235	COG2990	Protein conserved in bacteria
MKR81_25245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MKR81_25250	COG2866	Carboxypeptidase
MKR81_25260	COG0583	DNA-binding transcription factor activity
MKR81_25285	COG3104	oligopeptide transport
MKR81_25290	COG1760	l-serine dehydratase
MKR81_25315	COG1388	LysM domain
MKR81_25315	COG0741	lytic transglycosylase activity
MKR81_25335	COG1815	bacterial-type flagellum-dependent cell motility
MKR81_25340	COG1558	bacterial-type flagellum-dependent cell motility
MKR81_25345	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MKR81_25350	COG1749	Flagellar hook protein flgE
MKR81_25355	COG4787	bacterial-type flagellum-dependent cell motility
MKR81_25360	COG4786	Flagellar basal body rod
MKR81_25365	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MKR81_25370	COG1706	bacterial-type flagellum-dependent cell motility
MKR81_25380	COG1256	bacterial-type flagellum assembly
MKR81_25380	COG4786	Flagellar basal body rod
MKR81_25385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKR81_25450	COG0384	phenazine biosynthesis protein PhzF
MKR81_25475	COG1360	Flagellar Motor Protein
MKR81_25480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MKR81_25485	COG1191	sigma factor activity
MKR81_25490	COG1580	Controls the rotational direction of flagella during chemotaxis
MKR81_25505	COG1516	flagellar protein fliS
MKR81_25510	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MKR81_25520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKR81_25535	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MKR81_25545	COG1987	bacterial-type flagellum assembly
MKR81_25605	COG2200	EAL domain
MKR81_25690	COG0346	lactoylglutathione lyase activity
MKR81_25715	COG0745	RESPONSE REGULATOR receiver
MKR81_25740	COG0156	8-amino-7-oxononanoate synthase activity
MKR81_25745	COG1063	alcohol dehydrogenase
MKR81_25770	COG2203	Gaf domain
MKR81_25770	COG2199	diguanylate cyclase activity
MKR81_25775	COG2223	nitrite transmembrane transporter activity
MKR81_25780	COG1063	alcohol dehydrogenase
MKR81_25790	COG0668	transmembrane transport
MKR81_25800	COG1304	FMN binding
MKR81_25805	COG1620	l-lactate permease
MKR81_25810	COG0583	DNA-binding transcription factor activity
MKR81_25815	COG1505	serine-type exopeptidase activity
MKR81_25820	COG4172	Belongs to the ABC transporter superfamily
MKR81_25830	COG1067	ATP-dependent peptidase activity
MKR81_25840	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MKR81_25860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKR81_25865	COG0437	4 iron, 4 sulfur cluster binding
MKR81_25870	COG0348	domain, Protein
MKR81_25895	COG1122	ATPase activity
MKR81_25905	COG1566	PFAM secretion protein HlyD family protein
MKR81_25935	COG0813	purine-nucleoside phosphorylase activity
MKR81_25940	COG3272	Protein of unknown function (DUF1722)
MKR81_25945	COG0789	Transcriptional regulator
MKR81_25950	COG0415	Belongs to the DNA photolyase family
MKR81_25955	COG1388	LysM domain
MKR81_25955	COG1376	ErfK ybiS ycfS ynhG family protein
MKR81_25965	COG0513	Belongs to the DEAD box helicase family
MKR81_25975	COG1770	oligopeptidase
MKR81_25980	COG4771	TonB-dependent receptor
MKR81_26000	COG0840	transmembrane signaling receptor activity
MKR81_26010	COG0573	inorganic phosphate transmembrane transporter activity
MKR81_26035	COG0577	efflux transmembrane transporter activity
MKR81_26035	COG1136	(ABC) transporter
MKR81_26040	COG1136	(ABC) transporter
MKR81_26085	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MKR81_26100	COG4974	Belongs to the 'phage' integrase family
MKR81_26105	COG0517	IMP dehydrogenase activity
MKR81_26135	COG2076	Multidrug Resistance protein
MKR81_26210	COG0776	regulation of translation
MKR81_26330	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MKR81_26465	COG1879	ABC-type sugar transport system periplasmic component
MKR81_26470	COG0745	RESPONSE REGULATOR receiver
MKR81_26525	COG1988	membrane-bound metal-dependent
MKR81_26550	COG4232	protein-disulfide reductase activity
MKR81_26640	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MKR81_26655	COG0754	glutathionylspermidine amidase activity
MKR81_26690	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MKR81_26740	COG4974	Belongs to the 'phage' integrase family
MKR81_26850	COG2885	chlorophyll binding
MKR81_26960	COG0616	signal peptide processing
MKR81_27135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MKR81_27245	COG0210	DNA helicase
MKR81_27250	COG2353	YceI-like domain
MKR81_27295	COG0592	DNA-directed DNA polymerase activity
MKR81_27315	COG3141	response to X-ray
MKR81_27425	COG5295	Hep Hag repeat protein
MKR81_27515	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MKR81_27615	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MKR81_27630	COG1737	Transcriptional regulator
MKR81_27645	COG3069	C4-dicarboxylate transmembrane transporter activity
MKR81_27650	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MKR81_27820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MKR81_27845	COG3015	lipoprotein NlpE involved in copper resistance
MKR81_27960	COG2261	transglycosylase associated protein
MKR81_27995	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MKR81_28035	COG3081	Nucleoid-associated protein
MKR81_28090	COG1192	Involved in chromosome partitioning
MKR81_28130	COG2003	Belongs to the UPF0758 family
MKR81_28150	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MKR81_28190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MKR81_28225	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MKR81_28400	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MKR81_28410	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MKR81_28415	COG0732	type I restriction modification DNA specificity domain
MKR81_28420	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MKR81_28470	COG1192	Involved in chromosome partitioning
MKR81_28510	COG2026	Addiction module toxin, RelE StbE family
MKR81_28545	COG5268	conjugation
MKR81_28550	COG3451	type IV secretory pathway VirB4
MKR81_28560	COG4962	Type ii secretion system protein e
MKR81_28570	COG3701	Conjugal transfer protein
MKR81_28575	COG2026	Addiction module toxin, RelE StbE family
MKR81_28615	COG1192	Involved in chromosome partitioning
MKR81_28675	COG1403	HNH endonuclease