locus-tag	class	description
CAY59_00005	ENOG4105CBX	hi0933 family
CAY59_00035	ENOG4105CBX	hi0933 family
CAY59_00040	ENOG4108V6B	universal stress protein B
CAY59_00045	ENOG41090A1	ferritin
CAY59_00050	ENOG4108M6U	Universal stress protein A
CAY59_00055	ENOG4105EMK	carboxylate amino acid amine transporter
CAY59_00065	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
CAY59_00070	ENOG4105BZU	Histidine kinase
CAY59_00075	ENOG4108VVK	transcriptional Regulator, AsnC
CAY59_00080	ENOG4105DGW	oligopeptidase A
CAY59_00090	ENOG4105D6S	protein involved in catabolism of external DNA
CAY59_00100	ENOG4105DC8	reductase
CAY59_00105	ENOG4108UHU	Aldolase
CAY59_00110	ENOG4105C6Z	Gluconate
CAY59_00115	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
CAY59_00120	ENOG4105C01	Dihydroxy-acid dehydratase
CAY59_00130	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
CAY59_00135	ENOG41064T2	transcriptional regulator, lysR family
CAY59_00140	ENOG4105DIQ	Transcriptional regulator
CAY59_00145	ENOG4107QPV	Serine Threonine protein kinase
CAY59_00175	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CAY59_00180	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CAY59_00190	ENOG4108JQ6	ABC transporter
CAY59_00200	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
CAY59_00230	ENOG4105MPD	Cytochrome
CAY59_00235	ENOG4105C4R	Atp-dependent dna helicase
CAY59_00240	ENOG4107Z3H	Transcriptional regulator, TetR family
CAY59_00245	ENOG410624X	efflux transporter, rnd family, mfp subunit
CAY59_00250	ENOG4105BZS	acriflavin resistance protein
CAY59_00255	ENOG4105W0Z	cytoplasmic protein
CAY59_00265	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CAY59_00270	ENOG4105EMY	transcriptional regulator
CAY59_00315	ENOG4108RR8	protoporphyrinogen oxidase
CAY59_00320	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CAY59_00325	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CAY59_00330	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CAY59_00335	ENOG4105CHU	acetyl-coa acetyltransferase
CAY59_00340	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
CAY59_00355	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
CAY59_00370	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
CAY59_00375	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
CAY59_00385	ENOG4105EB3	Histidine kinase
CAY59_00460	ENOG4105JKW	Valine--pyruvate aminotransferase
CAY59_00465	ENOG4108ZNX	Heat shock protein
CAY59_00470	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CAY59_00475	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CAY59_00480	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CAY59_00485	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CAY59_00495	ENOG4105EAB	amino acid AbC transporter
CAY59_00500	ENOG4105E5Q	amino acid AbC transporter
CAY59_00505	ENOG4105CDA	abc transporter atp-binding protein
CAY59_00515	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CAY59_00520	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CAY59_00525	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CAY59_00530	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CAY59_00535	ENOG4105QTB	Flavodoxin
CAY59_00540	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CAY59_00545	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CAY59_00555	ENOG4105FA0	parb-like partition protein
CAY59_00560	ENOG410684E	atp synthase
CAY59_00565	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
CAY59_00570	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CAY59_00575	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CAY59_00580	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CAY59_00585	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CAY59_00590	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CAY59_00595	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CAY59_00600	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CAY59_00605	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CAY59_00610	ENOG4105EAD	ABC transporter
CAY59_00620	ENOG4105CZQ	inner membrane transport protein YdhC
CAY59_00625	ENOG4105F52	Transcriptional regulator
CAY59_00630	ENOG4106TD9	Diguanylate cyclase
CAY59_00635	ENOG4105C7B	Threonine dehydratase
CAY59_00640	ENOG4105C01	Dihydroxy-acid dehydratase
CAY59_00645	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CAY59_00650	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
CAY59_00660	ENOG4105C0P	Mg chelatase subunit ChlI
CAY59_00680	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CAY59_00685	ENOG4105DZR	Type I site-specific deoxyribonuclease
CAY59_00690	ENOG4105EKX	Restriction modification system DNA (Specificity
CAY59_00695	ENOG4105CVR	type I restriction-modification system
CAY59_00725	ENOG4105C0P	Mg chelatase subunit ChlI
CAY59_00730	ENOG4108KHX	Diguanylate cyclase
CAY59_00740	ENOG4106HNH	Acyl-transferase
CAY59_00745	ENOG4108Z33	Thiol disulfide Interchange Protein
CAY59_00750	ENOG4105E27	serine threonine protein kinase
CAY59_00760	ENOG4105PC1	Conserved Protein
CAY59_00765	ENOG4108N23	SpoOM-related protein
CAY59_00770	ENOG4108UT2	hemolysin iii
CAY59_00780	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CAY59_00785	ENOG4105C1A	potassium transporter peripheral membrane
CAY59_00790	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CAY59_00795	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CAY59_00810	ENOG4105C79	DNA protecting protein DprA
CAY59_00815	ENOG4108RPN	Protein smg homolog
CAY59_00820	ENOG4108WI1	Dna topoisomerase
CAY59_00825	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
CAY59_00830	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CAY59_00835	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CAY59_00840	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
CAY59_00845	ENOG4105E2X	shikimate dehydrogenase
CAY59_00855	ENOG4108Z0R	Transferase
CAY59_00900	ENOG4105E3B	Multicopper oxidase
CAY59_00905	ENOG4105WMR	Protein CrcB homolog
CAY59_00920	ENOG4105D06	uba thif-type nad fad binding protein
CAY59_00925	ENOG4105WHD	thiamine biosynthesis protein ThiS
CAY59_00930	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CAY59_00935	ENOG4105D41	biosynthesis protein thiH
CAY59_00940	ENOG4105DC7	peptidase M24
CAY59_00940	ENOG4105DC7	peptidase M24
CAY59_00945	ENOG4105G2Y	Transcriptional regulator
CAY59_00950	ENOG4105CNH	Multidrug resistance protein MdtL
CAY59_00970	ENOG4105E18	UPF0276 protein
CAY59_00980	ENOG4105C4R	Atp-dependent dna helicase
CAY59_00990	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CAY59_01015	ENOG4105FR1	rard protein
CAY59_01020	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CAY59_01030	ENOG4105EX9	Membrane
CAY59_01035	ENOG4105C9X	ppx gppa phosphatase
CAY59_01040	ENOG4105C1J	atp-dependent rna helicase
CAY59_01045	ENOG4105K63	Thioredoxin
CAY59_01050	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CAY59_01060	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
CAY59_01065	ENOG4108ZIT	Ferredoxin, 2FE-2S
CAY59_01070	ENOG4107QK7	reductase
CAY59_01105	ENOG410601J	HemY protein
CAY59_01110	ENOG4105ECF	c-methyltransferase
CAY59_01115	ENOG41076E6	Uroporphyrinogen-III Synthase
CAY59_01120	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CAY59_01125	ENOG4107T0K	Adenylate cyclase
CAY59_01130	ENOG4105XQ6	frataxin-like protein
CAY59_01140	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CAY59_01145	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CAY59_01155	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CAY59_01160	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
CAY59_01165	ENOG4105BZU	Histidine kinase
CAY59_01170	ENOG4106IUH	DTW domain containing protein
CAY59_01185	ENOG4105DQF	Hydrolase
CAY59_01190	ENOG4108EUD	Lysophospholipase
CAY59_01195	ENOG410829K	Lysine exporter protein (Lyse ygga)
CAY59_01200	ENOG4105D58	Diguanylate phosphodiesterase
CAY59_01205	ENOG41082YX	Transcriptional regulator, arsr family
CAY59_01210	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CAY59_01265	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
CAY59_01275	ENOG4106H78	methyltransferase
CAY59_01280	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CAY59_01285	ENOG4105CAK	Cell division ATP-binding protein ftsE
CAY59_01290	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CAY59_01295	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAY59_01305	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
CAY59_01310	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
CAY59_01315	ENOG4105X6C	Flagellar basal body-associated protein FliL
CAY59_01320	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
CAY59_01325	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
CAY59_01330	ENOG4105E55	glycerol-3-phosphate acyltransferase
CAY59_01340	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CAY59_01350	ENOG4107R73	Mate efflux family protein
CAY59_01355	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
CAY59_01370	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
CAY59_01375	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CAY59_01385	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CAY59_01465	ENOG4105JIM	Phosphatidylserine synthase
CAY59_01475	ENOG4105D4A	Cell wall formation (By similarity)
CAY59_01480	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CAY59_01485	ENOG4105CS9	pantothenic acid kinase
CAY59_01515	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CAY59_01520	ENOG4105PM1	preprotein translocase subunit SecE
CAY59_01525	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CAY59_01530	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CAY59_01535	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CAY59_01540	ENOG4108VZM	50s ribosomal protein L10
CAY59_01545	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CAY59_01550	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CAY59_01555	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CAY59_01560	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
CAY59_01565	ENOG4105E09	nadh pyrophosphatase
CAY59_01580	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CAY59_01585	ENOG4108RG0	uracil-dna glycosylase
CAY59_01590	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
CAY59_01595	ENOG4105R2J	Conserved Protein
CAY59_01615	ENOG4105C12	Phosphoribosylglycinamide synthetase
CAY59_01620	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CAY59_01625	ENOG4105W1Y	Transcriptional regulator
CAY59_01630	ENOG4108M3R	transcriptional activator CadC
CAY59_01640	ENOG4105D5Q	Arginine ornithine antiporter
CAY59_01645	ENOG4105CXN	decarboxylase
CAY59_01690	ENOG4105BZU	Histidine kinase
CAY59_01695	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
CAY59_01700	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CAY59_01705	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CAY59_01710	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CAY59_01715	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CAY59_01720	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CAY59_01725	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CAY59_01740	ENOG4105D8G	Major Facilitator superfamily
CAY59_01745	ENOG4105BZU	Histidine kinase
CAY59_01750	ENOG4105C9Q	fumarate hydratase class II
CAY59_01765	ENOG4107QN1	sodium solute
CAY59_01775	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
CAY59_01790	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
CAY59_01795	ENOG4108IJ0	Aspartate ammonia-lyase
CAY59_01800	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
CAY59_01805	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CAY59_01815	ENOG4105E0F	Histidine kinase
CAY59_01820	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CAY59_01830	ENOG41076HS	cation diffusion facilitator family transporter
CAY59_01835	ENOG4105CTQ	phosphohexokinase
CAY59_01840	ENOG4107QI1	Mate efflux family protein
CAY59_01845	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CAY59_01850	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CAY59_01865	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
CAY59_01870	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CAY59_01885	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
CAY59_01890	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
CAY59_01905	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
CAY59_01915	ENOG41062JF	Transcriptional regulator
CAY59_01925	ENOG41063SB	peptidase
CAY59_01930	ENOG4105D7W	serine acetyltransferase
CAY59_01935	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CAY59_01940	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
CAY59_01945	ENOG4107YZP	Rhodanese domain protein
CAY59_01950	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CAY59_02000	ENOG4105C8P	)-transporter
CAY59_02005	ENOG4105DJ4	phosphatidylserine decarboxylase
CAY59_02010	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CAY59_02015	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
CAY59_02085	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
CAY59_02090	ENOG4105K8N	protein family UPF0079, ATPase
CAY59_02095	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CAY59_02100	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CAY59_02105	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CAY59_02110	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
CAY59_02115	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CAY59_02120	ENOG4107QJR	hflk protein
CAY59_02125	ENOG4105EPW	hflc protein
CAY59_02135	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CAY59_02140	ENOG4108UV7	flagellar protein motX
CAY59_02145	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CAY59_02150	ENOG4105KPV	Transcriptional regulator
CAY59_02155	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CAY59_02160	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CAY59_02165	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CAY59_02170	ENOG4105C31	Tryptophanyl-tRNA synthetase
CAY59_02185	ENOG4105DDQ	anthranilate synthase
CAY59_02190	ENOG4105C8Y	Acetylornithine aminotransferase
CAY59_02200	ENOG4105C26	Dehydrogenase
CAY59_02210	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
CAY59_02215	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
CAY59_02220	ENOG4105YP7	UPF0270 protein
CAY59_02225	ENOG4105DNZ	Alpha Beta Hydrolase
CAY59_02235	ENOG4105C5H	ABC transporter
CAY59_02240	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
CAY59_02255	ENOG4108YZY	peptidylprolyl cis-trans isomerase
CAY59_02260	ENOG4105D44	asparaginase
CAY59_02265	ENOG41069P5	Protein slyX homolog
CAY59_02275	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CAY59_02280	ENOG4105WWK	YheO domain protein
CAY59_02285	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
CAY59_02290	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
CAY59_02295	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
CAY59_02300	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CAY59_02305	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CAY59_02310	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CAY59_02315	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CAY59_02320	ENOG4105W53	bacterioferritin-associated ferredoxin
CAY59_02325	ENOG4108UQY	Iron-storage protein
CAY59_02330	ENOG4105C6K	Malic enzyme
CAY59_02335	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
CAY59_02340	ENOG4105C28	cystathionine
CAY59_02345	ENOG4105CFH	Aspartokinase
CAY59_02350	ENOG4105SYT	Methylenetetrahydrofolate reductase
CAY59_02360	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
CAY59_02365	ENOG4105CWC	Acetylornithine deacetylase
CAY59_02370	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CAY59_02375	ENOG4105CAS	nag kinase
CAY59_02380	ENOG4105CDH	Citrulline--aspartate ligase
CAY59_02385	ENOG4105CH7	arginosuccinase
CAY59_02395	ENOG4107QN2	dihydrolipoyl dehydrogenase
CAY59_02400	ENOG4105EHV	domain protein
CAY59_02405	ENOG4105C5Q	Transcriptional regulator
CAY59_02410	ENOG4108JQC	penicillin-binding protein 1A
CAY59_02435	ENOG4105E4G	Type IV pilus
CAY59_02440	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CAY59_02445	ENOG4105D49	3-dehydroquinate synthase
CAY59_02455	ENOG4105DFE	Dna adenine methylase
CAY59_02460	ENOG4105DJV	ribulose-phosphate 3-epimerase
CAY59_02465	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CAY59_02470	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
CAY59_02475	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CAY59_02480	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CAY59_02490	ENOG4105CDU	Replicative dna helicase
CAY59_02495	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CAY59_02505	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
CAY59_02510	ENOG4107QP8	phosphohexose isomerase
CAY59_02520	ENOG4105MYN	Zinc uptake regulation protein
CAY59_02525	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CAY59_02545	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CAY59_02550	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
CAY59_02555	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
CAY59_02620	ENOG4105CFH	Aspartokinase
CAY59_02630	ENOG4105C5R	Aminotransferase
CAY59_02640	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CAY59_02645	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CAY59_02650	ENOG41086KC	Transcriptional regulator
CAY59_02655	ENOG4108UUM	single-stranded DNA-binding protein
CAY59_02660	ENOG41062P1	Diguanylate cyclase phosphodiesterase
CAY59_02695	ENOG4107QHF	type ii secretion system protein e
CAY59_02700	ENOG4105D7Q	type ii secretion system
CAY59_02745	ENOG4105DFF	Rod shape-determining protein mreb
CAY59_02750	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
CAY59_02755	ENOG4105VQ7	Rod shape-determining protein MreD
CAY59_02760	ENOG4108Z03	MAF-like protein
CAY59_02770	ENOG4105QD6	exported protein
CAY59_02780	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CAY59_02785	ENOG4108IAB	Phoh family
CAY59_02790	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
CAY59_02795	ENOG4105K3M	)-transporter
CAY59_02800	ENOG4105D3G	Pseudouridine synthase
CAY59_02805	ENOG4105C5I	Dehydrogenase
CAY59_02810	ENOG4105N42	UPF0307 protein
CAY59_02815	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CAY59_02820	ENOG4105CJW	magnesium transporter
CAY59_02825	ENOG41080Z8	PHOSPHOCARRIER protein
CAY59_02830	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CAY59_02835	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
CAY59_02840	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
CAY59_02845	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAY59_02855	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
CAY59_02865	ENOG4105C2X	Arabinose 5-phosphate isomerase
CAY59_02875	ENOG4105DHJ	ABC, transporter
CAY59_02880	ENOG4105CY3	ABC transporter, permease
CAY59_02885	ENOG4107PE3	Mammalian cell entry related domain protein
CAY59_02890	ENOG4105E3I	toluene tolerance
CAY59_02900	ENOG4105VFK	BolA family
CAY59_02905	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CAY59_02910	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
CAY59_02915	ENOG4105KME	endoribonuclease L-psp
CAY59_02920	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
CAY59_02925	ENOG4105CXT	aspartate transcarbamylase
CAY59_02935	ENOG4105DBV	ornithine carbamoyltransferase
CAY59_02940	ENOG4105CEU	Arginine dihydrolase
CAY59_02955	ENOG4108MJ3	acetyltransferase
CAY59_02965	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CAY59_02970	ENOG4105MYG	DNA polymerase iii, chi subunit
CAY59_02975	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CAY59_02980	ENOG4108M8S	permease YjgP YjgQ family protein
CAY59_02985	ENOG4108K5H	permease YjgP YjgQ family protein
CAY59_02995	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
CAY59_03010	ENOG4105VZJ	PTS System
CAY59_03020	ENOG4105VCP	PTS System
CAY59_03035	ENOG4105ETE	Transcriptional regulator (LacI family
CAY59_03040	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CAY59_03090	ENOG4105C26	Dehydrogenase
CAY59_03120	ENOG4105C8Q	Methyl-accepting chemotaxis
CAY59_03165	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
CAY59_03170	ENOG4105CEN	a g-specific adenine glycosylase
CAY59_03175	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CAY59_03185	ENOG4105CSV	Glutaminase
CAY59_03190	ENOG4105CSA	Coproporphyrinogen iii oxidase
CAY59_03195	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CAY59_03205	ENOG4105VZ9	UPF0235 protein
CAY59_03210	ENOG4108VIA	integral membrane protein
CAY59_03215	ENOG4105II7	pyrroline-5-carboxylate reductase
CAY59_03220	ENOG4105DFA	alanine racemase domain protein
CAY59_03225	ENOG4105CZX	twitching motility protein
CAY59_03230	ENOG4105CZX	twitching motility protein
CAY59_03235	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CAY59_03240	ENOG4108UJU	UPF0301 protein
CAY59_03245	ENOG4105D7Z	glutathione synthase
CAY59_03250	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CAY59_03255	ENOG4105RWS	endonuclease I
CAY59_03260	ENOG4105GPY	SprT protein
CAY59_03270	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CAY59_03275	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CAY59_03285	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CAY59_03290	ENOG4105BZA	Phosphoglycerate kinase
CAY59_03295	ENOG4105D2N	Aldolase
CAY59_03300	ENOG4105D64	Mechanosensitive ion channel
CAY59_03315	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
CAY59_03320	ENOG4105MPN	Membrane
CAY59_03325	ENOG4108JQ1	Dehydrogenase
CAY59_03330	ENOG4105E66	phosphoriboisomerase A
CAY59_03335	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CAY59_03345	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
CAY59_03355	ENOG4105D0A	hydroxylase
CAY59_03360	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CAY59_03375	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
CAY59_03380	ENOG4105Y75	tpr repeat protein
CAY59_03390	ENOG4108IYU	L-aspartate oxidase
CAY59_03395	ENOG4105EMN	RNA polymerase sigma factor
CAY59_03415	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CAY59_03420	ENOG4105C3F	Signal peptidase i
CAY59_03425	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CAY59_03430	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CAY59_03435	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
CAY59_03440	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CAY59_03445	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CAY59_03450	ENOG4105BZU	Histidine kinase
CAY59_03460	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CAY59_03465	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CAY59_03470	ENOG4105DXN	mazG family
CAY59_03475	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CAY59_03490	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CAY59_03495	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CAY59_03500	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CAY59_03505	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
CAY59_03510	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CAY59_03515	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CAY59_03525	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAY59_03530	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CAY59_03535	ENOG4107TH8	cina domain protein
CAY59_03540	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CAY59_03545	ENOG4105Y3E	Modulates RecA activity (By similarity)
CAY59_03550	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CAY59_03555	ENOG4105CFH	Aspartokinase
CAY59_03560	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
CAY59_03620	ENOG4107QSA	Oxaloacetate decarboxylase
CAY59_03625	ENOG4105D9Q	decarboxylase (Beta subunit)
CAY59_03635	ENOG4105W39	Membrane
CAY59_03645	ENOG4105D9M	gamma-glutamylcysteine synthetase
CAY59_03655	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
CAY59_03660	ENOG4108JU6	CBS domain protein
CAY59_03665	ENOG4106KVJ	cytochrome C assembly protein
CAY59_03670	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CAY59_03675	ENOG4105K5M	30s ribosomal protein S16
CAY59_03680	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CAY59_03685	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CAY59_03690	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CAY59_03700	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
CAY59_03705	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
CAY59_03710	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CAY59_03715	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
CAY59_03725	ENOG4107QHF	type ii secretion system protein e
CAY59_03740	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CAY59_03750	ENOG41073TP	transcriptional regulator
CAY59_03755	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
CAY59_03760	ENOG4107QSN	dihydrolipoamide acetyltransferase
CAY59_03765	ENOG4107QN2	dihydrolipoyl dehydrogenase
CAY59_03770	ENOG410630P	Transcriptional regulator
CAY59_03775	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CAY59_03780	ENOG41077A9	carbonic anhydrase
CAY59_03785	ENOG4105CHH	sulfate transporter
CAY59_03790	ENOG4105DA5	(ABC) transporter
CAY59_03795	ENOG4105E3A	(ABC) transporter
CAY59_03800	ENOG4105D1S	lipid A biosynthesis
CAY59_03805	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CAY59_03810	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CAY59_03815	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CAY59_03820	ENOG4105DJ0	Poly(A) Polymerase
CAY59_03825	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
CAY59_03830	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CAY59_03835	ENOG4105PW4	Sugar fermentation stimulation protein homolog
CAY59_03840	ENOG4105CQ7	ATP-dependent helicase
CAY59_03845	ENOG4105BZ4	penicillin-binding protein
CAY59_03850	ENOG4105D78	K07001 NTE family protein
CAY59_03855	ENOG4107QIJ	Aconitate hydratase 2
CAY59_03860	ENOG4105XTV	UPF0231 protein
CAY59_03865	ENOG4108YZA	Nitrogen regulatory protein pii
CAY59_03885	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CAY59_03900	ENOG4105E2D	ec 3.2.1.52
CAY59_03905	ENOG4105RD7	BadF BadG BcrA BcrD
CAY59_03915	ENOG4108JQ7	(ABC) transporter
CAY59_03920	ENOG4105C3U	ABC transporter
CAY59_03925	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CAY59_03935	ENOG4107QRA	Extracellular solute-binding protein, family 5
CAY59_03950	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CAY59_03955	ENOG4105F4G	Membrane
CAY59_03970	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CAY59_03975	ENOG4105CW7	secretion protein, HlyD family
CAY59_03980	ENOG4105BZS	acriflavin resistance protein
CAY59_03985	ENOG4105DR5	peptidase
CAY59_03990	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CAY59_04005	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
CAY59_04010	ENOG4107QE9	Inherit from COG: Membrane
CAY59_04015	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CAY59_04020	ENOG4105HBR	Rna-binding protein
CAY59_04025	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
CAY59_04030	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CAY59_04035	ENOG4105EEI	dihydropteroate synthase
CAY59_04040	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CAY59_04065	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CAY59_04070	ENOG4105CHV	Transcription elongation factor NusA
CAY59_04075	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CAY59_04080	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CAY59_04085	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CAY59_04090	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CAY59_04095	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CAY59_04110	ENOG4105C3S	Mate efflux family protein
CAY59_04115	ENOG4106RZ4	Peptidase U32
CAY59_04120	ENOG4105CFP	Peptidase U32
CAY59_04125	ENOG4105BZU	Histidine kinase
CAY59_04130	ENOG4105XPQ	lipid carrier protein
CAY59_04135	ENOG4108YYD	acetyltransferase
CAY59_04155	ENOG4105BZU	Histidine kinase
CAY59_04160	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CAY59_04165	ENOG4105EYA	deoxyribonuclease
CAY59_04170	ENOG4105D9N	nucleoside
CAY59_04175	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
CAY59_04180	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
CAY59_04185	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
CAY59_04190	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
CAY59_04200	ENOG4105EAC	phosphoserine phosphatase
CAY59_04210	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CAY59_04245	ENOG4108IQE	Amp-dependent synthetase and ligase
CAY59_04330	ENOG41064T2	transcriptional regulator, lysR family
CAY59_04335	ENOG4107WCA	isomerase
CAY59_04340	ENOG4107W6W	Conserved Protein
CAY59_04345	ENOG4105E5D	amino acid
CAY59_04350	ENOG4105FK9	beta-D-galactosidase beta subunit
CAY59_04355	ENOG4105CNT	hydrolase family 2
CAY59_04360	ENOG4105CQ4	Transcriptional regulator
CAY59_04365	ENOG4105CJN	penicillin-binding protein
CAY59_04370	ENOG4105CMR	udp-glucose 4-epimerase
CAY59_04375	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
CAY59_04380	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
CAY59_04385	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CAY59_04390	ENOG41060NJ	transcriptional regulator
CAY59_04395	ENOG4105CI1	PTS System
CAY59_04405	ENOG4108Y51	tRNA-binding protein
CAY59_04430	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
CAY59_04435	ENOG4105E98	transcriptional regulator DeoR family
CAY59_04440	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CAY59_04450	ENOG4105CXY	transporter
CAY59_04455	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
CAY59_04470	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
CAY59_04485	ENOG4105X2V	dna damage-inducible protein
CAY59_04490	ENOG4105EVZ	LysR family transcriptional regulator
CAY59_04500	ENOG4105E68	Sulfatase
CAY59_04505	ENOG4105DSY	exodeoxyribonuclease V, gamma
CAY59_04510	ENOG4107QKA	exodeoxyribonuclease V beta
CAY59_04515	ENOG4107QYX	exodeoxyribonuclease v alpha
CAY59_04535	ENOG4107QZM	n-acetylglutamate synthase
CAY59_04550	ENOG4105CA3	membrane-bound lytic murein transglycosylase
CAY59_04555	ENOG4105CUZ	uba thif-type nad fad binding protein
CAY59_04560	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
CAY59_04565	ENOG4105C9B	Cysteine desulfurase
CAY59_04570	ENOG4107S0N	DJ-1 family
CAY59_04575	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CAY59_04580	ENOG4105DRB	nucleoside-specific channel-forming protein
CAY59_04595	ENOG4105K6V	RNA polymerase
CAY59_04610	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CAY59_04620	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CAY59_04625	ENOG4105M85	Bola protein
CAY59_04630	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CAY59_04635	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CAY59_04640	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CAY59_04645	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CAY59_04650	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CAY59_04655	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
CAY59_04660	ENOG4105CJ2	(LipO)protein
CAY59_04670	ENOG4105BZU	Histidine kinase
CAY59_04680	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CAY59_04685	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CAY59_04700	ENOG4105C8J	)-transporter
CAY59_04710	ENOG4105W1I	UPF0253 protein
CAY59_04720	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CAY59_04725	ENOG4108R96	Methyltransferase, YaeB family
CAY59_04730	ENOG4105NRA	50s ribosomal protein l31 type b
CAY59_04740	ENOG4105CFC	Transporter
CAY59_04745	ENOG4108UPT	UPF0178 protein
CAY59_04775	ENOG4105WP7	tRNA pseudouridine synthase C
CAY59_04780	ENOG4105DR9	pseudouridine synthase
CAY59_04785	ENOG4108T8E	UPF0325 protein
CAY59_04790	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
CAY59_04795	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CAY59_04800	ENOG4105CE9	30S ribosomal protein S2
CAY59_04805	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CAY59_04810	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CAY59_04815	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CAY59_04820	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CAY59_04825	ENOG4105KNE	Phosphatidate cytidylyltransferase
CAY59_04830	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CAY59_04835	ENOG4105DZP	Membrane-associated zinc metalloprotease
CAY59_04845	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
CAY59_04850	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CAY59_04855	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CAY59_04860	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CAY59_04865	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CAY59_04870	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CAY59_04875	ENOG4105C0B	DNA polymerase III (alpha subunit)
CAY59_04880	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CAY59_04885	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CAY59_04890	ENOG4105N7H	Cytochrome
CAY59_04895	ENOG4108YZA	Nitrogen regulatory protein pii
CAY59_04900	ENOG4107NA1	Endonuclease Exonuclease phosphatase
CAY59_04910	ENOG4105E9H	Lytic Murein transglycosylase
CAY59_04915	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CAY59_04920	ENOG4105D1A	Methyltransferase
CAY59_04925	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CAY59_04930	ENOG4107RZZ	dna polymerase iii epsilon subunit
CAY59_04950	ENOG41090VV	Protein of unknown function (DUF2846)
CAY59_04960	ENOG4107QPN	acyl-Coa dehydrogenase
CAY59_04965	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CAY59_04970	ENOG4105E7A	Glutamine amidotransferase
CAY59_04975	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CAY59_04980	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CAY59_04985	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CAY59_04990	ENOG4105C2W	permease
CAY59_05005	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CAY59_05010	ENOG4105K89	arsenate reductase
CAY59_05015	ENOG4105ERG	peptidase m48, ste24p
CAY59_05030	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CAY59_05035	ENOG4105RH4	Glycine cleavage system transcriptional repressor
CAY59_05045	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CAY59_05060	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CAY59_05065	ENOG4105KUZ	arsenate reductase
CAY59_05090	ENOG4105QZU	Inner membrane protein YfeZ
CAY59_05095	ENOG4105EZR	dyp-type peroxidase family protein
CAY59_05100	ENOG4108K2B	transcriptional regulator
CAY59_05105	ENOG4105F8D	glycoside hydrolase family 4
CAY59_05110	ENOG4105CT4	transporter
CAY59_05120	ENOG4105I03	Flagellin
CAY59_05130	ENOG4105I03	Flagellin
CAY59_05135	ENOG4105I03	Flagellin
CAY59_05140	ENOG41063QE	flagellar protein FlaG
CAY59_05145	ENOG4107BRV	flagellar capping protein
CAY59_05155	ENOG4105MQ3	flagellar protein FliS
CAY59_05165	ENOG4105BZU	Histidine kinase
CAY59_05170	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAY59_05175	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
CAY59_05180	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CAY59_05185	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CAY59_05220	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CAY59_05225	ENOG4105DD5	Flagellar motor switch protein
CAY59_05230	ENOG4105VTB	flagellar biosynthesis protein fliO
CAY59_05235	ENOG4105CN7	Flagellar biosynthetic protein FliP
CAY59_05240	ENOG4105VS8	Flagellar biosynthetic protein fliq
CAY59_05245	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CAY59_05250	ENOG4105D00	flagellar biosynthetic protein flhB
CAY59_05255	ENOG4105D7B	Flagellar biosynthesis protein flha
CAY59_05260	ENOG4105FZW	flagellar biosynthesis regulator FlhF
CAY59_05265	ENOG4107R21	site-determining protein
CAY59_05270	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAY59_05275	ENOG4108VYJ	response regulator receiver protein
CAY59_05280	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
CAY59_05285	ENOG4105CBS	Chea signal transduction histidine kinase
CAY59_05290	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CAY59_05295	ENOG4107QJE	Chromosome Partitioning Protein
CAY59_05305	ENOG4108V3W	Chemotaxis protein, CheW
CAY59_05315	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
CAY59_05320	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
CAY59_05325	ENOG41060IM	Heme exporter protein
CAY59_05335	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
CAY59_05340	ENOG4105DA4	cytochrome c-type biogenesis protein
CAY59_05345	ENOG4107QX9	Thiol disulfide interChange protein
CAY59_05350	ENOG4108M1T	Cytochrome c-type biogenesis protein
CAY59_05355	ENOG4105KWW	Biogenesis protein
CAY59_05360	ENOG410903C	(LipO)protein
CAY59_05365	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CAY59_05390	ENOG4105CHU	acetyl-coa acetyltransferase
CAY59_05395	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CAY59_05405	ENOG4107QXK	peptidase
CAY59_05410	ENOG4108BY2	phosphohistidine phosphatase
CAY59_05415	ENOG4108DG9	Smr protein MutS2
CAY59_05420	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
CAY59_05425	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CAY59_05430	ENOG4105EN6	Membrane
CAY59_05435	ENOG4108BPE	-transporting atpase
CAY59_05440	ENOG4105MH2	YfcL protein
CAY59_05455	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
CAY59_05460	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CAY59_05470	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
CAY59_05485	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CAY59_05495	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CAY59_05500	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CAY59_05505	ENOG4108S3P	Sporulation domain protein
CAY59_05510	ENOG4105E96	Colicin v production protein
CAY59_05515	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CAY59_05520	ENOG4105EJC	lysr family transcriptional regulator
CAY59_05530	ENOG4105WD1	Membrane
CAY59_05535	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CAY59_05540	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CAY59_05545	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CAY59_05550	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CAY59_05555	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CAY59_05560	ENOG4105C44	Serine transporter
CAY59_05575	ENOG4105WWK	YheO domain protein
CAY59_05580	ENOG4105KRS	Proteinase inhibitor
CAY59_05585	ENOG4108ZZ3	UPF0260 protein
CAY59_05590	ENOG4105Y3U	Transglycosylase-associated protein
CAY59_05595	ENOG4105D0C	transport protein
CAY59_05600	ENOG4105CVK	Glutamate decarboxylase
CAY59_05615	ENOG4108UYE	Lactoylglutathione lyase
CAY59_05625	ENOG4105G6Z	alkaline phosphatase
CAY59_05630	ENOG4105C94	Transporter
CAY59_05645	ENOG4105DHI	Methyltransferase
CAY59_05660	ENOG4105DSB	aldose 1-epimerase
CAY59_05665	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CAY59_05680	ENOG4105VUT	cytoplasmic protein
CAY59_05685	ENOG4105HDK	L-asparaginase
CAY59_05690	ENOG4105D07	Signal peptide peptidase, SppA
CAY59_05695	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CAY59_05700	ENOG41069NU	Nitroreductase
CAY59_05705	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CAY59_05715	ENOG4108RU0	short-chain dehydrogenase reductase
CAY59_05720	ENOG4105DGU	Histone deacetylase
CAY59_05730	ENOG4108M3P	Membrane
CAY59_05745	ENOG4105E68	Sulfatase
CAY59_05750	ENOG4105YDX	UPF0352 protein
CAY59_05755	ENOG4106V8H	Nucleoid-associated protein
CAY59_05770	ENOG4105DFD	Na H antiporter
CAY59_05775	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CAY59_05780	ENOG4105EYW	Ion transport protein
CAY59_05785	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
CAY59_05790	ENOG4108EKI	Dehydrogenase
CAY59_05795	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
CAY59_05805	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CAY59_05810	ENOG4105M2J	Glutaredoxin
CAY59_05820	ENOG4105D3Y	Na H antiporter
CAY59_05825	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
CAY59_05830	ENOG4105EIY	sodium-type flagellar protein motY
CAY59_05835	ENOG4106WH9	Protein of unknown function (DUF2753)
CAY59_05840	ENOG4108UYE	Lactoylglutathione lyase
CAY59_05845	ENOG4105CSM	endonuclease III
CAY59_05850	ENOG4105DZB	Electron transport complex
CAY59_05855	ENOG4108UQQ	Electron transport complex
CAY59_05860	ENOG4105D6A	Electron transport complex
CAY59_05870	ENOG4108R3D	Electron transport complex
CAY59_05875	ENOG4105DGN	Electron transport complex
CAY59_05880	ENOG4105C6N	Formate acetyltransferase
CAY59_05890	ENOG41065U4	response regulator
CAY59_05925	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CAY59_05930	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAY59_05940	ENOG4105CHW	UPF0052 protein
CAY59_05945	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CAY59_05950	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CAY59_05955	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CAY59_05960	ENOG4105M00	molybdopterin converting factor, subunit 1
CAY59_05965	ENOG4108ZAF	Molybdopterin
CAY59_05970	ENOG4107QSI	ABC, transporter
CAY59_05975	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CAY59_05980	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CAY59_05985	ENOG4105C3U	ABC transporter
CAY59_05990	ENOG4108JQ7	(ABC) transporter
CAY59_05995	ENOG4105CHF	Glutathione S-transferase
CAY59_06000	ENOG4107PU6	Membrane
CAY59_06005	ENOG4108DNC	Involved in acetate metabolism (By similarity)
CAY59_06010	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CAY59_06015	ENOG4105PQ6	UPF0208 membrane protein
CAY59_06025	ENOG4105C7J	ABC transporter, permease
CAY59_06030	ENOG4108JJB	ABC transporter
CAY59_06035	ENOG4107R28	alpha amylase, catalytic region
CAY59_06040	ENOG4105BZU	Histidine kinase
CAY59_06045	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
CAY59_06050	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CAY59_06055	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
CAY59_06060	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CAY59_06065	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
CAY59_06075	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CAY59_06080	ENOG4105D1F	ATP-binding protein
CAY59_06085	ENOG4105DBI	uridine monophosphokinase
CAY59_06095	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CAY59_06105	ENOG4105CHH	sulfate transporter
CAY59_06115	ENOG4105C03	ribonuclease
CAY59_06120	ENOG4105EI2	Pseudouridine synthase
CAY59_06125	ENOG4108UHJ	MAF-like protein
CAY59_06130	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
CAY59_06135	ENOG4105VGS	50s ribosomal protein l32
CAY59_06140	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CAY59_06145	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CAY59_06150	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CAY59_06155	ENOG4105CHR	reductase
CAY59_06160	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CAY59_06165	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CAY59_06175	ENOG4105HHA	aminodeoxychorismate lyase
CAY59_06180	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CAY59_06185	ENOG4107QRG	dna polymerase iii
CAY59_06190	ENOG4105F8V	Hydrolase, tatD family
CAY59_06195	ENOG4105CI1	PTS System
CAY59_06205	ENOG4105C8J	)-transporter
CAY59_06215	ENOG4108NRW	Phospholipase, patatin family
CAY59_06240	ENOG4105EBR	Carboxylesterase
CAY59_06250	ENOG4108M3R	transcriptional activator CadC
CAY59_06260	ENOG4105CA9	Pyruvate kinase
CAY59_06265	ENOG4105DAG	ROK family
CAY59_06270	ENOG4107R88	Chemotaxis protein (CheV)
CAY59_06275	ENOG4105C0B	DNA polymerase III (alpha subunit)
CAY59_06290	ENOG4105UBK	short-chain dehydrogenase reductase
CAY59_06295	ENOG4105ERU	peptidase
CAY59_06300	ENOG4105CAT	Cytidine monophosphate kinase
CAY59_06315	ENOG4105Q4A	inner membrane protein yciS
CAY59_06320	ENOG4105CFV	Tetratricopeptide repeat protein
CAY59_06325	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
CAY59_06350	ENOG4108Q2G	(LipO)protein
CAY59_06355	ENOG4105DY2	Paraquat-inducible protein b
CAY59_06360	ENOG4105F1S	paraquat-inducible protein a
CAY59_06365	ENOG41060NJ	transcriptional regulator
CAY59_06380	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
CAY59_06395	ENOG4105CT4	transporter
CAY59_06400	ENOG4105DHT	Metal Dependent Phosphohydrolase
CAY59_06405	ENOG4105JQN	Transcriptional regulator
CAY59_06420	ENOG4105N6Y	Thioredoxin
CAY59_06430	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CAY59_06445	ENOG4108MK9	spermidine N(1)-acetyltransferase
CAY59_06465	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CAY59_06475	ENOG4107RBB	ABC transporter, permease
CAY59_06485	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CAY59_06500	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CAY59_06550	ENOG4105J12	Multidrug resistance protein mdtN
CAY59_06555	ENOG4105EQ2	LysR family Transcriptional regulator
CAY59_06590	ENOG41062D9	Histidine kinase
CAY59_06595	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CAY59_06605	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
CAY59_06615	ENOG4105C8Q	Methyl-accepting chemotaxis
CAY59_06630	ENOG4105E2B	Taurine dioxygenase
CAY59_06635	ENOG4105WWK	YheO domain protein
CAY59_06645	ENOG4107R6U	sodium dicarboxylate symporter
CAY59_06650	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
CAY59_06675	ENOG4105CCT	upf0313 protein
CAY59_06700	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
CAY59_06710	ENOG4105K9H	YciI-like protein
CAY59_06715	ENOG4105NAU	thioesterase Superfamily protein
CAY59_06720	ENOG4107835	probably involved in intracellular septation (By similarity)
CAY59_06730	ENOG4105BZU	Histidine kinase
CAY59_06740	ENOG4105CK2	sodium dicarboxylate symporter
CAY59_06745	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CAY59_06750	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CAY59_06755	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CAY59_06760	ENOG4108I0Q	anthranilate phosphoribosyltransferase
CAY59_06765	ENOG4105DDQ	anthranilate synthase
CAY59_06770	ENOG4105CRQ	synthase (Component I)
CAY59_06780	ENOG4105DB7	PHP domain protein
CAY59_06785	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
CAY59_06795	ENOG4105FE9	pseudouridine synthase
CAY59_06800	ENOG4108W5H	UPF0263 protein
CAY59_06815	ENOG4105CQ2	DNA polymerase
CAY59_06820	ENOG4105WH1	Two component transcriptional regulator luxr family
CAY59_06825	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CAY59_06870	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
CAY59_06885	ENOG4108DQR	cina-like protein
CAY59_06895	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CAY59_06900	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CAY59_06905	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CAY59_06910	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CAY59_06925	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
CAY59_06935	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CAY59_06940	ENOG4105DVI	reductase, NrfD
CAY59_06945	ENOG4105DA4	cytochrome c-type biogenesis protein
CAY59_06950	ENOG4107QX9	Thiol disulfide interChange protein
CAY59_06955	ENOG4108DMF	Cytochrome C biogenesis protein
CAY59_06965	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
CAY59_06990	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
CAY59_06995	ENOG4105EAQ	(twin-arginine translocation) pathway signal
CAY59_07000	ENOG4105C5X	domain protein
CAY59_07015	ENOG4105CH5	extracellular solute-binding protein, family 7
CAY59_07025	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CAY59_07040	ENOG41067TZ	transcriptional regulator, MarR family
CAY59_07045	ENOG4105C94	Transporter
CAY59_07050	ENOG4105C8Q	Methyl-accepting chemotaxis
CAY59_07070	ENOG4105CGF	Aromatic amino acid aminotransferase
CAY59_07090	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CAY59_07110	ENOG4105C8Q	Methyl-accepting chemotaxis
CAY59_07115	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
CAY59_07120	ENOG4105WH1	Two component transcriptional regulator luxr family
CAY59_07130	ENOG4105BZU	Histidine kinase
CAY59_07135	ENOG4105EJQ	L-serine dehydratase
CAY59_07140	ENOG4105C44	Serine transporter
CAY59_07155	ENOG4105BZU	Histidine kinase
CAY59_07160	ENOG4105CRQ	synthase (Component I)
CAY59_07175	ENOG4105CM6	amino acid regulated cytosolic protein
CAY59_07180	ENOG4106K28	UPF0283 membrane protein
CAY59_07190	ENOG4105D9U	N-acetyltransferase
CAY59_07470	ENOG4108MTT	Glutamate-rich protein grpB
CAY59_07860	ENOG4105EMU	Dehydrogenase
CAY59_07905	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
CAY59_07910	ENOG4105C8P	)-transporter
CAY59_07915	ENOG4105BZU	Histidine kinase
CAY59_07920	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAY59_07925	ENOG4105BZU	Histidine kinase
CAY59_07930	ENOG4105CPI	Metal Dependent Phosphohydrolase
CAY59_07940	ENOG4105G0K	glycine radical enzyme YjjI family
CAY59_07945	ENOG41076CZ	activating enzyme
CAY59_07955	ENOG4105EE5	Membrane protein terC
CAY59_07965	ENOG4105DHT	Metal Dependent Phosphohydrolase
CAY59_07970	ENOG4105PDP	Short chain dehydrogenase
CAY59_07980	ENOG4105E0U	tyrosine-specific transport protein
CAY59_08000	ENOG4105BZ1	(ABC) transporter
CAY59_08005	ENOG4105BZ1	(ABC) transporter
CAY59_08015	ENOG4105CR8	Transcriptional regulator
CAY59_08040	ENOG4105CFG	Acts as a chaperone (By similarity)
CAY59_08045	ENOG4105CFG	Acts as a chaperone (By similarity)
CAY59_08055	ENOG4105BZU	Histidine kinase
CAY59_08085	ENOG4105D4Y	metalloprotease
CAY59_08105	ENOG4108IJ9	(ABC) transporter
CAY59_08110	ENOG4107T40	Inherit from COG: Glycosyltransferase 36
CAY59_08130	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
CAY59_08140	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
CAY59_08145	ENOG4107QY8	reductase
CAY59_08150	ENOG4105QAX	Iron-sulfur
CAY59_08155	ENOG4107KGK	dmso reductase anchor subunit
CAY59_08160	ENOG4108NEM	leader-binding protein dmsD
CAY59_08170	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CAY59_08175	ENOG4105CQ7	ATP-dependent helicase
CAY59_08200	ENOG41090FY	type IV pilus biogenesis stability protein PilW
CAY59_08205	ENOG4105CVG	Homoserine O-transsuccinylase
CAY59_08230	ENOG4105E5D	amino acid
CAY59_08240	ENOG4105D1S	lipid A biosynthesis
CAY59_08245	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
CAY59_08260	ENOG4105CTD	carboxy-peptidase
CAY59_08265	ENOG410829K	Lysine exporter protein (Lyse ygga)
CAY59_08280	ENOG4107QMS	site-determining protein
CAY59_08285	ENOG4107Y8H	Aerolysin toxin
CAY59_08300	ENOG4105BZG	amino acid carrier protein
CAY59_08320	ENOG4105E0M	Sulfatase
CAY59_08325	ENOG4105C8N	cysteinyl-tRNA synthetase
CAY59_08330	ENOG4107QI1	Mate efflux family protein
CAY59_08335	ENOG41080XQ	Signal transduction protein with cbs domains
CAY59_08345	ENOG4105C94	Transporter
CAY59_08350	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
CAY59_08355	ENOG4108JPW	Aminotransferase
CAY59_08360	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
CAY59_08365	ENOG4105CZK	Aspartate kinase
CAY59_08380	ENOG4105CA0	peroxidase
CAY59_08385	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CAY59_08390	ENOG4105D4Y	metalloprotease
CAY59_08405	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CAY59_08410	ENOG4105E2X	shikimate dehydrogenase
CAY59_08415	ENOG4105JSC	dimethylmenaquinone methyltransferase
CAY59_08425	ENOG4105GAK	amidohydrolase 2
CAY59_08445	ENOG4105CPC	Aldo Keto reductase
CAY59_08460	ENOG4107RSM	transcriptional regulator
CAY59_08465	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CAY59_08470	ENOG41069H7	transport system small permease component
CAY59_08475	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CAY59_08480	ENOG4107TT2	Auxin Efflux Carrier
CAY59_08490	ENOG4105WZ4	isomerase
CAY59_08520	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
CAY59_08525	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
CAY59_08540	ENOG4107ZT5	Thiol disulfide interchange protein
CAY59_08560	ENOG4105CUW	cytochrome C-TYPE protein
CAY59_08575	ENOG4108KSA	LysR family transcriptional regulator
CAY59_08590	ENOG4107V40	secretion protein, HlyD family
CAY59_08605	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
CAY59_08610	ENOG4108V9W	transcriptional regulatory protein
CAY59_08615	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
CAY59_08620	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
CAY59_08625	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
CAY59_08655	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
CAY59_08660	ENOG4105C26	Dehydrogenase
CAY59_08670	ENOG4105EJ9	Membrane
CAY59_08715	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CAY59_08755	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CAY59_08825	ENOG4105CR4	methylisocitrate lyase
CAY59_08830	ENOG4105BZN	citrate synthase
CAY59_08835	ENOG4108I0Z	Aconitate hydratase
CAY59_08840	ENOG4105C7F	AcnD-accessory protein PrpF
CAY59_08845	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CAY59_08850	ENOG41064T2	transcriptional regulator, lysR family
CAY59_08855	ENOG4105ENH	Sulfatase
CAY59_08865	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
CAY59_08875	ENOG410667J	hydrolase
CAY59_08880	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CAY59_08885	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CAY59_08890	ENOG4105BZU	Histidine kinase
CAY59_08900	ENOG4105CDV	Ompa motb domain protein
CAY59_08930	ENOG4105CDV	Ompa motb domain protein
CAY59_08945	ENOG4105DR4	Methyltransferase
CAY59_08955	ENOG4105C8Q	Methyl-accepting chemotaxis
CAY59_08960	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
CAY59_08965	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
CAY59_08975	ENOG4108MN8	Membrane
CAY59_08980	ENOG4105CDA	abc transporter atp-binding protein
CAY59_08985	ENOG4105DRP	amino acid AbC transporter
CAY59_08990	ENOG4105EZ7	amino acid ABC transporter
CAY59_08995	ENOG4107QXX	ABC transporter
CAY59_09005	ENOG4108VPT	UPF0234 protein
CAY59_09010	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CAY59_09030	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CAY59_09035	ENOG4105DY2	Paraquat-inducible protein b
CAY59_09040	ENOG4105H2K	paraquat-inducible protein a
CAY59_09045	ENOG4105BZ1	(ABC) transporter
CAY59_09050	ENOG4108ZGC	gaf domain protein
CAY59_09055	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
CAY59_09060	ENOG4105CN1	protease
CAY59_09070	ENOG4105CD8	aminopeptidase N
CAY59_09080	ENOG4105C7I	Dehydrogenase
CAY59_09085	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CAY59_09090	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
CAY59_09095	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
CAY59_09105	ENOG4105C5H	ABC transporter
CAY59_09120	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
CAY59_09125	ENOG4105DAN	ATP-dependent protease
CAY59_09130	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
CAY59_09155	ENOG4105BZU	Histidine kinase
CAY59_09170	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
CAY59_09185	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
CAY59_09195	ENOG4105C59	p-type ATPase
CAY59_09210	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CAY59_09215	ENOG4105Q9Y	Universal stress protein
CAY59_09220	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CAY59_09240	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CAY59_09245	ENOG4105F38	ABC transporter, permease
CAY59_09250	ENOG4105D38	putrescine abc transporter
CAY59_09255	ENOG4107RUE	extracellular solute-binding protein family 1
CAY59_09260	ENOG4107RUE	extracellular solute-binding protein family 1
CAY59_09265	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CAY59_09285	ENOG4105QAX	Iron-sulfur
CAY59_09290	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CAY59_09300	ENOG4108SBI	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
CAY59_09320	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CAY59_09325	ENOG4105DIJ	Phosphoethanolamine transferase
CAY59_09330	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
CAY59_09335	ENOG4105C5H	ABC transporter
CAY59_09350	ENOG4105BZU	Histidine kinase
CAY59_09355	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAY59_09365	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
CAY59_09370	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CAY59_09375	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CAY59_09380	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CAY59_09390	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
CAY59_09395	ENOG4106IUH	DTW domain containing protein
CAY59_09445	ENOG4108N3W	hemolysin secretion protein
CAY59_09450	ENOG4107TT5	NLP P60 protein
CAY59_09460	ENOG4105BZU	Histidine kinase
CAY59_09465	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CAY59_09470	ENOG4105FGM	Fructosamine kinase
CAY59_09485	ENOG4107QI1	Mate efflux family protein
CAY59_09500	ENOG41082AN	stage II sporulation protein
CAY59_09505	ENOG4107QKZ	Ompa motb domain protein
CAY59_09510	ENOG4107V1M	polysaccharide export protein
CAY59_09525	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAY59_09530	ENOG4107SBE	Glycosyl transferase (Group 1
CAY59_09535	ENOG4105CPK	Glycosyl transferase (Group 1
CAY59_09565	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CAY59_09570	ENOG4105CND	Glycosyl transferase, family 2
CAY59_09585	ENOG4105F88	accessory colonization factor AcfD
CAY59_09610	ENOG4105BZU	Histidine kinase
CAY59_09635	ENOG4108UW5	maltose o-acetyltransferase
CAY59_09660	ENOG4108ZT1	Transcriptional regulator
CAY59_09670	ENOG4105EIP	mannose-6-phosphate isomerase
CAY59_09705	ENOG4105C8I	hydrolase, family 38
CAY59_09715	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
CAY59_09740	ENOG4108YK4	Acid-resistance membrane protein
CAY59_09745	ENOG4105CUY	Mechanosensitive ion channel
CAY59_09755	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CAY59_09760	ENOG4108MA4	Peptidase M66
CAY59_09765	ENOG4107QHE	Choloylglycine hydrolase
CAY59_09815	ENOG4105D6U	Sodium Glutamate Symporter
CAY59_09840	ENOG4108RXX	maleylacetoacetate isomerase
CAY59_09850	ENOG4105F1J	Homogentisate 1,2-dioxygenase
CAY59_09855	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
CAY59_09865	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
CAY59_09900	ENOG4108QW8	Purine nucleoside phosphorylase deoD-type
CAY59_09915	ENOG4105BZU	Histidine kinase
CAY59_09920	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
CAY59_09925	ENOG4108VKG	metal-dependent hydrolase
CAY59_09935	ENOG4107VGF	ig domain protein group 2 domain protein
CAY59_09950	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CAY59_09960	ENOG4105BZU	Histidine kinase
CAY59_10020	ENOG4106855	Competence protein
CAY59_10045	ENOG4105F04	LysR family Transcriptional regulator
CAY59_10070	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
CAY59_10075	ENOG4108IU2	vtamin B12-transporter permease
CAY59_10080	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
CAY59_10090	ENOG410902C	phosphohistidine phosphatase, SixA
CAY59_10100	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
CAY59_10105	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CAY59_10110	ENOG4107XWI	flavin reductase domain protein, FMN-binding
CAY59_10120	ENOG4105K4T	epimerase
CAY59_10125	ENOG4108ETY	sodium dicarboxylate symporter
CAY59_10135	ENOG4105CJB	Exodeoxyribonuclease I
CAY59_10140	ENOG4105VAW	lrga family
CAY59_10145	ENOG41067MG	lrgb family
CAY59_10150	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
CAY59_10165	ENOG4105FQ6	thiopurine methyltransferase
CAY59_10175	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CAY59_10230	ENOG4105C0W	non-ribosomal peptide synthetase
CAY59_10235	ENOG4107SJ9	decarboxylase
CAY59_10250	ENOG4105WQI	isochorismatase
CAY59_10255	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CAY59_10260	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CAY59_10300	ENOG4105K8R	UPF0145 protein
CAY59_10305	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
CAY59_10310	ENOG4105KME	endoribonuclease L-psp
CAY59_10330	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CAY59_10335	ENOG41082NX	50s ribosomal protein l35
CAY59_10340	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CAY59_10345	ENOG4105C22	threonyL-tRNA synthetase
CAY59_10355	ENOG4105CZE	histidine utilization repressor
CAY59_10360	ENOG4105CI2	imidazolone-5-propionate hydrolase
CAY59_10365	ENOG41088SP	formiminoglutamate hydrolase
CAY59_10370	ENOG4105CGP	Urocanate hydratase
CAY59_10375	ENOG4105C84	Histidine ammonia-lyase
CAY59_10420	ENOG4105CQB	FAD linked oxidase domain protein
CAY59_10435	ENOG4105CDV	Ompa motb domain protein
CAY59_10460	ENOG4105C8V	SAICAR synthetase
CAY59_10480	ENOG4105CQ7	ATP-dependent helicase
CAY59_10485	ENOG4107R1I	NAD-dependent malic enzyme
CAY59_10490	ENOG4107GZ4	SanA protein
CAY59_10495	ENOG4105C8P	)-transporter
CAY59_10500	ENOG4105BZU	Histidine kinase
CAY59_10530	ENOG4105C3M	thioredoxin reductase
CAY59_10535	ENOG4108JJ9	ABC, transporter
CAY59_10540	ENOG4108JJ8	(ABC) transporter
CAY59_10545	ENOG4105BZC	d-serine deaminase
CAY59_10555	ENOG4105W8I	Transcriptional regulator
CAY59_10560	ENOG4105BZU	Histidine kinase
CAY59_10610	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CAY59_10620	ENOG4105BZU	Histidine kinase
CAY59_10645	ENOG4105DWU	Membrane
CAY59_10655	ENOG4105DY8	decarboxylase
CAY59_10660	ENOG4106KNT	transcriptional regulator
CAY59_10670	ENOG41090BQ	Glutaredoxin
CAY59_10675	ENOG4105D0C	transport protein
CAY59_10680	ENOG4105RKW	reductase (By
CAY59_10685	ENOG4107QPN	acyl-Coa dehydrogenase
CAY59_10690	ENOG41067SE	Tetr family transcriptional regulator
CAY59_10695	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CAY59_10710	ENOG4108I0Y	(ABC) transporter
CAY59_10715	ENOG4107QI1	Mate efflux family protein
CAY59_10720	ENOG4105CGD	Nad-dependent epimerase dehydratase
CAY59_10725	ENOG4108NRW	Phospholipase, patatin family
CAY59_10735	ENOG4105C2C	drug resistance transporter, Bcr CflA
CAY59_10740	ENOG4105I08	Pseudouridine synthase
CAY59_10745	ENOG4105CFI	type iii restriction protein res subunit
CAY59_10750	ENOG4105BZU	Histidine kinase
CAY59_10760	ENOG4105ETX	regulatoR
CAY59_10765	ENOG4105EB3	Histidine kinase
CAY59_10780	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CAY59_10795	ENOG4105CGH	5'-nucleotidase
CAY59_10810	ENOG4105XZD	Fe-S protein
CAY59_10820	ENOG4105CHH	sulfate transporter
CAY59_10830	ENOG4108ZXC	Two component transcriptional regulator, luxr family
CAY59_10835	ENOG4106AFQ	Histidine kinase
CAY59_10845	ENOG4105BZ8	glutamate synthase
CAY59_10855	ENOG4108RSN	SNARE associated Golgi
CAY59_10860	ENOG4105VNH	ABC transporter solute-binding protein
CAY59_10865	ENOG4105CXZ	ABC transporter, permease
CAY59_10870	ENOG4108VGW	abc transporter atp-binding protein
CAY59_10875	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
CAY59_10890	ENOG4108JUA	Transcriptional regulator
CAY59_10895	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
CAY59_10900	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CAY59_10910	ENOG4108W1A	pseudouridine synthase
CAY59_10920	ENOG4105C8J	)-transporter
CAY59_10930	ENOG4105C28	cystathionine
CAY59_10935	ENOG4107IFA	Lipase (EC 3.1.1.3)
CAY59_10955	ENOG4108R3E	Dna-3-methyladenine glycosylase i
CAY59_10975	ENOG4105FM1	phage shock protein C
CAY59_10980	ENOG4105YYT	phage shock protein B
CAY59_10985	ENOG41087YS	Phage shock protein A
CAY59_10990	ENOG4105E51	psp operon transcriptional activator
CAY59_10995	ENOG4108J59	Extracellular solute-binding protein, family 5
CAY59_11000	ENOG4108I5W	peptide transport system, permease protein
CAY59_11005	ENOG4108EU3	peptide transport system, permease
CAY59_11010	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
CAY59_11015	ENOG4108JQ2	peptide transport system atp-binding protein
CAY59_11025	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
CAY59_11055	ENOG4105C4B	ABC transporter, permease
CAY59_11060	ENOG4105TMB	Formate nitrite transporter
CAY59_11085	ENOG4105GFG	DUF218 domain
CAY59_11090	ENOG4107104	thymidine kinase
CAY59_11095	ENOG4105C8N	cysteinyl-tRNA synthetase
CAY59_11100	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CAY59_11105	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
CAY59_11110	ENOG4105D58	Diguanylate phosphodiesterase
CAY59_11115	ENOG4105K5B	UPF0225 protein
CAY59_11140	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CAY59_11145	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CAY59_11150	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CAY59_11155	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CAY59_11160	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAY59_11165	ENOG4107S6Z	Na H antiporter
CAY59_11170	ENOG4108YX2	DNA-binding protein
CAY59_11175	ENOG4107RE1	Inosine-guanosine kinase
CAY59_11185	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CAY59_11190	ENOG41075W9	High frequency lysogenization protein HflD homolog
CAY59_11195	ENOG4107QTF	adenylosuccinate lyase
CAY59_11215	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CAY59_11230	ENOG4107FW0	short-chain dehydrogenase reductase
CAY59_11240	ENOG4105D0M	Protease HtpX homolog
CAY59_11245	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CAY59_11255	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CAY59_11260	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CAY59_11270	ENOG4105KSC	Transcriptional regulator, TraR DksA family
CAY59_11285	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CAY59_11290	ENOG4105D1H	recombination factor protein RarA
CAY59_11305	ENOG4105EW9	transcriptional regulator AsnC family
CAY59_11310	ENOG4105DCF	alanine dehydrogenase
CAY59_11320	ENOG4107R11	Transcriptional regulator
CAY59_11330	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
CAY59_11345	ENOG4107QUY	Guanine deaminase
CAY59_11350	ENOG4105KXC	Collagenase
CAY59_11390	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
CAY59_11415	ENOG4105JXH	GntR family transcriptional regulator
CAY59_11425	ENOG4105BZS	acriflavin resistance protein
CAY59_11430	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CAY59_11445	ENOG4105C8Q	Methyl-accepting chemotaxis
CAY59_11460	ENOG4105DEF	Extracellular solute-binding protein, family 5
CAY59_11465	ENOG4108JQ7	(ABC) transporter
CAY59_11470	ENOG4105C3U	ABC transporter
CAY59_11480	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
CAY59_11500	ENOG4105ENH	Sulfatase
CAY59_11690	ENOG41066XE	Type III export protein
CAY59_11720	ENOG4108KB1	transcriptional regulator, arac family
CAY59_11760	ENOG4108RNS	Exports L-alanine (By similarity)
CAY59_11775	ENOG4106032	Glutathionylspermidine synthase
CAY59_11785	ENOG4105Z6B	inner membrane protein yjfl
CAY59_11795	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
CAY59_11800	ENOG4105UFD	tol-pal system protein YbgF
CAY59_11810	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
CAY59_11820	ENOG4105M8F	Biopolymer transport protein exbD tolR
CAY59_11825	ENOG4105E02	MotA TolQ exbB proton channel
CAY59_11845	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CAY59_11850	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CAY59_11860	ENOG4105C8Q	Methyl-accepting chemotaxis
CAY59_11865	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CAY59_11870	ENOG4105C9M	aspartyl-trna synthetase
CAY59_11875	ENOG41081XQ	Conserved Protein
CAY59_11880	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
CAY59_11885	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
CAY59_11890	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CAY59_11910	ENOG4105CEY	Amp-dependent synthetase and ligase
CAY59_11915	ENOG4107RGH	Aldehyde dehydrogenase
CAY59_11920	ENOG4108ZX5	transcriptional regulator
CAY59_11925	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
CAY59_11930	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
CAY59_11935	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
CAY59_11940	ENOG4106371	Methyltransferase
CAY59_11945	ENOG4107S90	membrAne
CAY59_11950	ENOG4106WF9	DNA-binding transcriptional regulator TorR
CAY59_11955	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
CAY59_11960	ENOG4105ETE	Transcriptional regulator (LacI family
CAY59_11965	ENOG4105HP8	regulator of competence-specific genes
CAY59_11985	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CAY59_11990	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CAY59_11995	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CAY59_12000	ENOG4105RKX	Protein of unknown function (DUF2498)
CAY59_12005	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CAY59_12015	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
CAY59_12020	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
CAY59_12025	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CAY59_12030	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CAY59_12035	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CAY59_12040	ENOG4105VEQ	Cold shock protein
CAY59_12050	ENOG4108R99	pseudouridine synthase
CAY59_12070	ENOG4105EJ9	Membrane
CAY59_12075	ENOG4108URS	primosomal replication protein n''
CAY59_12080	ENOG4106428	Protein of unknown function (DUF2496)
CAY59_12085	ENOG4105CGK	Exodeoxyribonuclease III
CAY59_12095	ENOG4105DSP	amino acid AbC transporter
CAY59_12100	ENOG4105E89	ABC transporter
CAY59_12105	ENOG4108JEH	abc transporter atp-binding protein
CAY59_12120	ENOG4105C6N	Formate acetyltransferase
CAY59_12130	ENOG4105F1A	Pyruvate formate-lyase
CAY59_12140	ENOG4105XWI	UPF0304 protein
CAY59_12145	ENOG4105CYN	Serine protein kinase
CAY59_12150	ENOG4106AKX	UPF0229 protein
CAY59_12155	ENOG4105ED1	spovr family
CAY59_12160	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CAY59_12165	ENOG4105W49	UPF0434 protein
CAY59_12170	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
CAY59_12175	ENOG4105BZ1	(ABC) transporter
CAY59_12180	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
CAY59_12190	ENOG4105D60	lipoprotein releasing system transmembrane protein
CAY59_12195	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CAY59_12200	ENOG4105D60	lipoprotein releasing system transmembrane protein
CAY59_12210	ENOG4108JA2	transcriptioN-repair coupling factor
CAY59_12225	ENOG4105CEP	NADH dehydrogenase
CAY59_12230	ENOG4105D0Y	UPF0227 protein
CAY59_12255	ENOG4105K59	histidine triad (HIT) protein
CAY59_12260	ENOG4108NVR	Methyl-accepting chemotaxis
CAY59_12270	ENOG4107SXA	Phosphorylase
CAY59_12275	ENOG4105C59	p-type ATPase
CAY59_12285	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CAY59_12290	ENOG4105DZ0	fad dependent oxidoreductase
CAY59_12295	ENOG4108Z4U	Ferredoxin
CAY59_12310	ENOG4105BZU	Histidine kinase
CAY59_12325	ENOG4108MNP	Glycoprotein polysaccharide metabolism
CAY59_12330	ENOG4105C29	acyl-CoA thioesterase
CAY59_12335	ENOG4108XM1	transcriptional regulator AsnC family
CAY59_12360	ENOG4105BZS	acriflavin resistance protein
CAY59_12415	ENOG4105HMI	Membrane
CAY59_12435	ENOG4105W8I	Transcriptional regulator
CAY59_12440	ENOG4105CI1	PTS System
CAY59_12445	ENOG4105CEY	Amp-dependent synthetase and ligase
CAY59_12450	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
CAY59_12455	ENOG4108IPT	Naphthoate synthase
CAY59_12460	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
CAY59_12465	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
CAY59_12470	ENOG4105E4F	Isochorismate synthase
CAY59_12475	ENOG4105CHM	Aminotransferase
CAY59_12480	ENOG4105DK2	UPF0207 protein
CAY59_12485	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
CAY59_12500	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
CAY59_12505	ENOG4105EIN	peptidylprolyl cis-trans isomerase
CAY59_12510	ENOG4105K70	DNA-binding protein
CAY59_12515	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CAY59_12520	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CAY59_12525	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CAY59_12530	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CAY59_12535	ENOG4105CQZ	Histidine kinase
CAY59_12540	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAY59_12550	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CAY59_12555	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
CAY59_12560	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CAY59_12565	ENOG4105CNG	UPF0061 protein
CAY59_12585	ENOG4107ZYR	domain protein
CAY59_12590	ENOG4105C1J	atp-dependent rna helicase
CAY59_12615	ENOG4105CEY	Amp-dependent synthetase and ligase
CAY59_12615	ENOG4105CEY	Amp-dependent synthetase and ligase
CAY59_12620	ENOG4105WQI	isochorismatase
CAY59_12625	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
CAY59_12630	ENOG4105E4F	Isochorismate synthase
CAY59_12640	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
CAY59_12665	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CAY59_12670	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
CAY59_12675	ENOG4105D9N	nucleoside
CAY59_12680	ENOG4105EQ2	LysR family Transcriptional regulator
CAY59_12685	ENOG4105CVE	Lytic murein transglycosylase
CAY59_12690	ENOG4105VNG	YcgL domain-containing protein
CAY59_12695	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CAY59_12700	ENOG4107QMS	site-determining protein
CAY59_12705	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
CAY59_12710	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
CAY59_12715	ENOG4105CEY	Amp-dependent synthetase and ligase
CAY59_12720	ENOG410832A	alpha/beta hydrolase fold
CAY59_12725	ENOG4105R8X	Outer membrane lipoprotein Slp
CAY59_12735	ENOG41072GX	Peptidase M22 Glycoprotease
CAY59_12740	ENOG4105DVT	helicase
CAY59_12755	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
CAY59_12765	ENOG4106ZCM	YecM protein
CAY59_12770	ENOG4105C75	arginyL-tRNA synthetase
CAY59_12795	ENOG4105XFK	Ferrous iron transport protein A
CAY59_12800	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
CAY59_12805	ENOG4105NXV	High-affinity zinc uptake system protein
CAY59_12810	ENOG4105FDK	ABC transporter
CAY59_12815	ENOG4105FAV	ABC, transporter
CAY59_12820	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
CAY59_12830	ENOG4105C7S	Dehydrogenase
CAY59_12835	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
CAY59_12840	ENOG4105E33	succinate dehydrogenase
CAY59_12845	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CAY59_12850	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
CAY59_12855	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
CAY59_12860	ENOG4105BZN	citrate synthase
CAY59_12865	ENOG4107QNR	UPF0135 protein
CAY59_12880	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
CAY59_12885	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
CAY59_12890	ENOG4105EV9	Alpha Beta Hydrolase
CAY59_12900	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
CAY59_12910	ENOG41090R7	Ferric uptake
CAY59_12915	ENOG4105CX6	glutaminyL-tRNA synthetase
CAY59_12920	ENOG4105CI1	PTS System
CAY59_12925	ENOG4105CE4	GlcNAc 6-P deacetylase
CAY59_12930	ENOG4105E2R	ROK family
CAY59_12935	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CAY59_12940	ENOG4105CAQ	asparagine synthetase
CAY59_12945	ENOG4105MDZ	Transcriptional activator rfaH
CAY59_12950	ENOG4105DUX	Transporter
CAY59_12955	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CAY59_12960	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CAY59_12965	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CAY59_12970	ENOG4108DQ1	activator toxR
CAY59_12990	ENOG4108RE9	Phosphodiesterase
CAY59_13020	ENOG4105ECP	epimerase
CAY59_13025	ENOG4105E1F	short-chain dehydrogenase reductase
CAY59_13035	ENOG4107QR8	Thioredoxin
CAY59_13040	ENOG4105EJG	cellulose synthase
CAY59_13045	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
CAY59_13050	ENOG4107EEX	Cellulose synthase regulator protein
CAY59_13055	ENOG4107QZ7	Cellulose synthase catalytic subunit
CAY59_13060	ENOG4105UTS	cellulose synthase operon protein YhjQ
CAY59_13075	ENOG4105D1V	cellulose synthase operon protein YhjU
CAY59_13080	ENOG4107QX8	SPFH domain, Band 7 family protein
CAY59_13105	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CAY59_13115	ENOG4105EXN	Sulfate transport protein CysZ
CAY59_13120	ENOG4105C6T	cysteine synthase
CAY59_13130	ENOG4105KZ7	phosphocarrier protein hpr
CAY59_13135	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CAY59_13140	ENOG4105C5Y	PTS System
CAY59_13150	ENOG4105I03	Flagellin
CAY59_13155	ENOG4105I03	Flagellin
CAY59_13170	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
CAY59_13175	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CAY59_13180	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CAY59_13185	ENOG4105CGA	flagellar basal-body rod protein FlgG
CAY59_13190	ENOG4108KPB	Flagellar basal-body rod protein FlgF
CAY59_13195	ENOG4105BZE	flagellar hook protein, FlgE
CAY59_13200	ENOG4105W00	Flagellar hook capping protein
CAY59_13205	ENOG4108ZC9	flagellar basal-body rod protein flgc
CAY59_13210	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
CAY59_13215	ENOG4105BZU	Histidine kinase
CAY59_13220	ENOG4107R88	Chemotaxis protein (CheV)
CAY59_13265	ENOG4105UYK	outer membrane protein a
CAY59_13280	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CAY59_13290	ENOG41081QG	Porin Gram-negative type
CAY59_13295	ENOG4105C59	p-type ATPase
CAY59_13310	ENOG4105E2D	ec 3.2.1.52
CAY59_13330	ENOG4108DG9	Smr protein MutS2
CAY59_13335	ENOG4105FE9	pseudouridine synthase
CAY59_13340	ENOG4108Z66	YbaK ebsC protein
CAY59_13345	ENOG4105CGH	5'-nucleotidase
CAY59_13350	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CAY59_13355	ENOG41063JG	Transcriptional regulator
CAY59_13360	ENOG4108YY7	Invasion gene expression up-regulator SirB
CAY59_13365	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CAY59_13375	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CAY59_13385	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CAY59_13390	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CAY59_13395	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CAY59_13400	ENOG4105C3G	gtp-binding protein
CAY59_13515	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CAY59_13520	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CAY59_13525	ENOG4105C9A	Phoh family
CAY59_13530	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CAY59_13535	ENOG4108JU5	Magnesium and cobalt efflux protein
CAY59_13540	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
CAY59_13545	ENOG4107PAI	alpha helical protein
CAY59_13550	ENOG4105C8T	Leucyl-tRNA synthetase
CAY59_13555	ENOG4108U2H	Rare lipoprotein B
CAY59_13560	ENOG4105DJF	DNA polymerase III, delta' subunit
CAY59_13565	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
CAY59_13570	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CAY59_13575	ENOG4105CJN	penicillin-binding protein
CAY59_13580	ENOG4105CNI	cell division protein FtsW
CAY59_13585	ENOG4105K6T	rare lipoprotein A
CAY59_13590	ENOG4105DZ1	carboxypeptidase
CAY59_13595	ENOG4108Z43	UPF0250 protein
CAY59_13600	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CAY59_13605	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CAY59_13610	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CAY59_13615	ENOG4108JYZ	YitT family
CAY59_13620	ENOG4105CG3	alpha amylase, catalytic region
CAY59_13625	ENOG4105C5Y	PTS System
CAY59_13630	ENOG4105D4X	repressor
CAY59_13635	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
CAY59_13640	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CAY59_13645	ENOG4108UMI	ABC transporter, permease
CAY59_13650	ENOG4105D01	(LipO)protein
CAY59_13660	ENOG4105CGH	5'-nucleotidase
CAY59_13665	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
CAY59_13670	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
CAY59_13675	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CAY59_13685	ENOG4105BZU	Histidine kinase
CAY59_13690	ENOG4105EWT	decarboxylase family
CAY59_13695	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
CAY59_13700	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
CAY59_13705	ENOG4105M08	Membrane
CAY59_13715	ENOG4105ETT	transcriptional Regulator, LysR family
CAY59_13720	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
CAY59_13725	ENOG4106VK6	Flagellar motor protein
CAY59_13730	ENOG4105E14	MotA TolQ exbB proton channel
CAY59_13735	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CAY59_13740	ENOG4105CTB	Polyprenyl synthetase
CAY59_13745	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CAY59_13750	ENOG4108ZAI	phosphatidylglycerophosphatase a
CAY59_13755	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CAY59_13760	ENOG4107YIM	Involved in the transcription termination process (By similarity)
CAY59_13765	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CAY59_13780	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CAY59_13785	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CAY59_13790	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CAY59_13795	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CAY59_13800	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
CAY59_13805	ENOG4108DJV	Fermentation respiration switch protein
CAY59_13810	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
CAY59_13815	ENOG4105C7N	Xanthine uracil vitamin C permease
CAY59_13820	ENOG4105CIN	aminoacyl-histidine dipeptidase
CAY59_13850	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
CAY59_13855	ENOG4108Z6B	deaminase
CAY59_13865	ENOG4105CFC	Transporter
CAY59_13885	ENOG4105X0D	Fimbrial protein
CAY59_13900	ENOG4105CFG	Acts as a chaperone (By similarity)
CAY59_13915	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CAY59_13920	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CAY59_13925	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CAY59_13930	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CAY59_13935	ENOG4105VDB	UPF0125 protein
CAY59_13940	ENOG4108Z1B	Cyclase dehydrase
CAY59_13945	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CAY59_13955	ENOG4105DFP	Integrase
CAY59_13980	ENOG4105EKX	Restriction modification system DNA (Specificity
CAY59_13985	ENOG4105DZR	Type I site-specific deoxyribonuclease
CAY59_13995	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
CAY59_14075	ENOG4105ETT	transcriptional Regulator, LysR family
CAY59_14080	ENOG410613R	integral membrane protein, YccS YhfK family
CAY59_14100	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CAY59_14105	ENOG4105EFZ	amidohydrolase
CAY59_14125	ENOG4107RSM	transcriptional regulator
CAY59_14130	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CAY59_14135	ENOG4105BZG	amino acid carrier protein
CAY59_14140	ENOG4106HK8	GPR1 FUN34 yaaH family protein
CAY59_14150	ENOG4107S6Z	Na H antiporter
CAY59_14155	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CAY59_14160	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CAY59_14165	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CAY59_14175	ENOG410620I	Diguanylate cyclase
CAY59_14185	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CAY59_14190	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CAY59_14195	ENOG4105N21	Membrane
CAY59_14200	ENOG4105CUT	histidyl-tRNA synthetase
CAY59_14205	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CAY59_14215	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CAY59_14220	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CAY59_14225	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CAY59_14230	ENOG4105WVQ	Fe-S assembly protein IscX
CAY59_14235	ENOG4108ZIT	Ferredoxin, 2FE-2S
CAY59_14240	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
CAY59_14245	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
CAY59_14250	ENOG4108Z4V	iron-sulfur cluster assembly
CAY59_14255	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
CAY59_14260	ENOG4105C3J	Cysteine desulfurase
CAY59_14265	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
CAY59_14270	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
CAY59_14275	ENOG4105ECY	inositol monophosphatase
CAY59_14280	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CAY59_14285	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CAY59_14290	ENOG4105VIE	preprotein translocase, subunit YajC
CAY59_14295	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CAY59_14300	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CAY59_14315	ENOG4105W87	Cbs domain
CAY59_14320	ENOG4108I9X	Isocitrate lyase
CAY59_14325	ENOG4107QP3	malate synthase g
CAY59_14330	ENOG4105C5Q	Transcriptional regulator
CAY59_14335	ENOG4105D3R	alkyl hydroperoxide reductase
CAY59_14345	ENOG4105CSR	polyphosphate kinase 2
CAY59_14365	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CAY59_14370	ENOG4105E2Z	phosphate ABC transporter (Permease
CAY59_14375	ENOG4105C8U	phosphate abc transporter
CAY59_14380	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CAY59_14385	ENOG4105C9X	ppx gppa phosphatase
CAY59_14400	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CAY59_14410	ENOG4105DH7	May be involved in recombination (By similarity)
CAY59_14415	ENOG4105CFP	Peptidase U32
CAY59_14420	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
CAY59_14475	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CAY59_14480	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CAY59_14485	ENOG4105C34	Pseudouridine synthase
CAY59_14490	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAY59_14495	ENOG4105E4C	Lytic transglycosylase catalytic
CAY59_14500	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
CAY59_14510	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CAY59_14515	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
CAY59_14520	ENOG4107SC1	transglycosylase
CAY59_14525	ENOG4105C5H	ABC transporter
CAY59_14535	ENOG4105DR5	peptidase
CAY59_14540	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
CAY59_14545	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CAY59_14550	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CAY59_14555	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
CAY59_14560	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CAY59_14580	ENOG4108HRK	Histidine kinase
CAY59_14585	ENOG4108NEV	two component transcriptional regulator, LytTR family
CAY59_14590	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CAY59_14595	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
CAY59_14600	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CAY59_14605	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CAY59_14610	ENOG4105DTN	riboflavin biosynthesis protein ribF
CAY59_14615	ENOG4105CJR	Integral membrane protein (MviN
CAY59_14620	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
CAY59_14625	ENOG41080HT	Transcriptional regulator, arsr family
CAY59_14630	ENOG41063Z6	transcriptional regulator, lysR family
CAY59_14645	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CAY59_14650	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CAY59_14655	ENOG4105HF0	Membrane
CAY59_14665	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CAY59_14670	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
CAY59_14680	ENOG4105CPC	Aldo Keto reductase
CAY59_14690	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAY59_14695	ENOG4105CRK	lysyL-tRNA synthetase
CAY59_14705	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CAY59_14710	ENOG4105T95	Thiol disulfide interChange protein
CAY59_14715	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CAY59_14720	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
CAY59_14725	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
CAY59_14730	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
CAY59_14735	ENOG4105C1J	atp-dependent rna helicase
CAY59_14745	ENOG4105D1Q	UPF0246 protein
CAY59_14750	ENOG4105BZG	amino acid carrier protein
CAY59_14765	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CAY59_14770	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
CAY59_14775	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
CAY59_14785	ENOG4105D98	threonine synthase
CAY59_14790	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
CAY59_14805	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CAY59_14815	ENOG41065U4	response regulator
CAY59_14840	ENOG4105N5T	Radical SAM Protein
CAY59_14855	ENOG4105CBC	glutamate synthase
CAY59_14860	ENOG4105BZ8	glutamate synthase
CAY59_14870	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CAY59_14880	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
CAY59_14885	ENOG4105EN6	Membrane
CAY59_14890	ENOG4105VP0	transcriptional regulator, lysR family
CAY59_14895	ENOG4105EJ9	Membrane
CAY59_14915	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CAY59_14920	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CAY59_14925	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CAY59_14930	ENOG4105M6F	mutator MutT protein
CAY59_14945	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CAY59_14950	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CAY59_14955	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CAY59_14960	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
CAY59_14965	ENOG4105DFU	Cell wall formation (By similarity)
CAY59_14970	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CAY59_14980	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CAY59_14985	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CAY59_14990	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
CAY59_14995	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CAY59_15000	ENOG4105CJN	penicillin-binding protein
CAY59_15005	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CAY59_15010	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CAY59_15020	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CAY59_15030	ENOG41082RQ	UPF0102 protein
CAY59_15035	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CAY59_15040	ENOG4105W4M	Transport-associated protein
CAY59_15045	ENOG4105KB2	stringent starvation protein b
CAY59_15050	ENOG4107MKT	Stringent starvation protein a
CAY59_15055	ENOG4105EIX	cytochrome c1
CAY59_15060	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CAY59_15065	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CAY59_15070	ENOG4108UJD	30S ribosomal protein S9
CAY59_15075	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CAY59_15080	ENOG4105D6Z	AFG1 family ATPase
CAY59_15085	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
CAY59_15090	ENOG4105C0H	protease
CAY59_15095	ENOG4105C0H	protease
CAY59_15100	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CAY59_15105	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CAY59_15110	ENOG4105IPS	esterase
CAY59_15115	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
CAY59_15120	ENOG4108SX3	cytoplasmic protein
CAY59_15125	ENOG41087AY	ADP-Ribose pyrophosphatase
CAY59_15130	ENOG4105DFG	type I secretion outer membrane protein
CAY59_15135	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CAY59_15145	ENOG4105C8Q	Methyl-accepting chemotaxis
CAY59_15155	ENOG4105I7R	Adenylate cyclase
CAY59_15160	ENOG4107IX6	phosphate transport regulator
CAY59_15165	ENOG4105CJ3	phosphate transporter
CAY59_15170	ENOG4106MWK	domain protein
CAY59_15190	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CAY59_15195	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CAY59_15200	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CAY59_15205	ENOG4107ZVW	dihydroneopterin aldolase
CAY59_15210	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CAY59_15215	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
CAY59_15220	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CAY59_15225	ENOG4105VCC	30S ribosomal protein S21
CAY59_15230	ENOG4105KTH	gatB Yqey
CAY59_15240	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CAY59_15275	ENOG4105CTS	PTS system mannitol-specific
CAY59_15280	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
CAY59_15285	ENOG4105E61	Mannitol repressor protein
CAY59_15290	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
CAY59_15315	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CAY59_15320	ENOG410804X	Transcriptional regulator
CAY59_15325	ENOG4105CA9	Pyruvate kinase
CAY59_15335	ENOG4105BZU	Histidine kinase
CAY59_15340	ENOG4108ZP8	Acetolactate synthase small subunit
CAY59_15345	ENOG4105C7K	acetolactate synthase
CAY59_15350	ENOG4108IQE	Amp-dependent synthetase and ligase
CAY59_15355	ENOG41064T2	transcriptional regulator, lysR family
CAY59_15380	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CAY59_15385	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CAY59_15390	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CAY59_15395	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CAY59_15405	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
CAY59_15410	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
CAY59_15415	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
CAY59_15420	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
CAY59_15425	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CAY59_15430	ENOG4105NWN	ApaG protein
CAY59_15435	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
CAY59_15440	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
CAY59_15445	ENOG4107XM3	UPF0442 protein
CAY59_15450	ENOG4105DWK	Membrane
CAY59_15455	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CAY59_15460	ENOG4105K46	50S ribosomal protein l27
CAY59_15465	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CAY59_15470	ENOG4105EAH	synthase
CAY59_15480	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CAY59_15485	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
CAY59_15505	ENOG4107T0D	ABC, transporter
CAY59_15510	ENOG4106SMU	thiamine transporter membrane protein
CAY59_15515	ENOG4105DP9	ABC transporter
CAY59_15520	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
CAY59_15525	ENOG4105DFU	Cell wall formation (By similarity)
CAY59_15530	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CAY59_15535	ENOG4105F0N	pyrophosphate phospho-hydrolase
CAY59_15550	ENOG41066HZ	AIG2-like family
CAY59_15560	ENOG4105CFU	surface antigen
CAY59_15565	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CAY59_15575	ENOG4108UUE	Transcriptional regulator
CAY59_15590	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CAY59_15610	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
CAY59_15620	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
CAY59_15625	ENOG4105C11	sulfate adenylyltransferase), subunit 2
CAY59_15630	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CAY59_15635	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
CAY59_15645	ENOG4105C1J	atp-dependent rna helicase
CAY59_15650	ENOG4107YB6	acetyltransferase, (GNAT) family
CAY59_15665	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CAY59_15675	ENOG4108ZT0	50S ribosomal protein l17
CAY59_15680	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CAY59_15685	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CAY59_15690	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CAY59_15695	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CAY59_15705	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CAY59_15710	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CAY59_15715	ENOG4105VPB	50S ribosomal protein L30
CAY59_15720	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CAY59_15730	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CAY59_15735	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CAY59_15740	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CAY59_15745	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CAY59_15750	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CAY59_15755	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CAY59_15760	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CAY59_15765	ENOG41083MP	50s ribosomal protein l29
CAY59_15770	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CAY59_15775	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CAY59_15780	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CAY59_15785	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CAY59_15790	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CAY59_15795	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CAY59_15800	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CAY59_15805	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CAY59_15810	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CAY59_15815	ENOG4105VFB	Binds the 23S rRNA (By similarity)
CAY59_15820	ENOG4105C25	Primosomal protein n'
CAY59_15825	ENOG4105ETE	Transcriptional regulator (LacI family
CAY59_15835	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
CAY59_15845	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
CAY59_15850	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CAY59_15855	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
CAY59_15860	ENOG4105CBT	Fructose-1,6-bisphosphatase
CAY59_15885	ENOG4105CP7	Triose-phosphate isomerase
CAY59_15915	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CAY59_15930	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CAY59_15940	ENOG4105C5E	polysaccharide biosynthesis protein
CAY59_15965	ENOG4108IJ1	Dehydrogenase
CAY59_15970	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CAY59_15975	ENOG4105CY0	Metallo-Beta-Lactamase
CAY59_15980	ENOG4105ESV	Glycosyl transferase, family 4
CAY59_15985	ENOG4105EIP	mannose-6-phosphate isomerase
CAY59_15995	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
CAY59_16045	ENOG4105DAY	polysaccharide export protein
CAY59_16070	ENOG4105E3R	(LipO)protein
CAY59_16075	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
CAY59_16080	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
CAY59_16085	ENOG4105XA0	heptosyltransferase ii
CAY59_16090	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
CAY59_16095	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CAY59_16100	ENOG4108UW5	maltose o-acetyltransferase
CAY59_16105	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CAY59_16110	ENOG4105F18	Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity)
CAY59_16120	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CAY59_16125	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
CAY59_16130	ENOG41080IJ	Diacylglycerol kinase
CAY59_16135	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CAY59_16140	ENOG4105DKP	glycosyl transferase, family 9
CAY59_16145	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
CAY59_16150	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CAY59_16180	ENOG4105KDC	50s ribosomal protein l28
CAY59_16185	ENOG4105W5Q	DNA repair protein (RadC
CAY59_16190	ENOG4105C8Q	Methyl-accepting chemotaxis
CAY59_16195	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CAY59_16200	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
CAY59_16205	ENOG4105D1S	lipid A biosynthesis
CAY59_16210	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CAY59_16220	ENOG4105DSJ	YicC domain protein
CAY59_16225	ENOG4105DWP	Membrane
CAY59_16240	ENOG4108JQ7	(ABC) transporter
CAY59_16250	ENOG4107QRA	Extracellular solute-binding protein, family 5
CAY59_16255	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
CAY59_16260	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
CAY59_16265	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CAY59_16285	ENOG4109015	Biopolymer transport protein exbD tolR
CAY59_16300	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CAY59_16305	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CAY59_16310	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CAY59_16315	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
CAY59_16320	ENOG4105CB5	ATP-dependent DNA helicase recG
CAY59_16330	ENOG4105C2W	permease
CAY59_16335	ENOG4105E0F	Histidine kinase
CAY59_16340	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CAY59_16345	ENOG4108RRZ	Transcription elongation factor GreB
CAY59_16355	ENOG4105BZM	domain protein
CAY59_16365	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CAY59_16370	ENOG4105MJ2	Competence protein
CAY59_16375	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
CAY59_16380	ENOG4107RK2	ADP-ribose diphosphatase NudE
CAY59_16385	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CAY59_16390	ENOG4105PIC	general secretion pathway protein N
CAY59_16395	ENOG4105U1E	general secretion pathway protein M
CAY59_16400	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
CAY59_16405	ENOG4108RTD	type II secretion system protein K
CAY59_16410	ENOG4108WWZ	General secretion pathway protein J
CAY59_16415	ENOG4105X5Z	General secretion pathway protein I
CAY59_16420	ENOG4105VWV	general secretion pathway protein h
CAY59_16425	ENOG4108VAU	general secretion pathway protein G
CAY59_16430	ENOG4105D7Q	type ii secretion system
CAY59_16435	ENOG4107QHF	type ii secretion system protein e
CAY59_16445	ENOG4108XKW	General secretion pathway protein C
CAY59_16450	ENOG4105VEJ	Heat shock protein
CAY59_16455	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CAY59_16460	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
CAY59_16470	ENOG4105SUU	thioesterase domain
CAY59_16475	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CAY59_16480	ENOG4107S2Z	UPF0761 membrane protein
CAY59_16505	ENOG4105C5F	glutamine synthetase
CAY59_16515	ENOG4105CUX	Signal transduction histidine kinase
CAY59_16520	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAY59_16525	ENOG4105BZU	Histidine kinase
CAY59_16530	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CAY59_16540	ENOG4105XCT	Protein of unknown function (DUF2489)
CAY59_16545	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
CAY59_16560	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CAY59_16565	ENOG4105C2M	dna polymerase I
CAY59_16580	ENOG4105D52	delta-aminolevulinic acid dehydratase
CAY59_16585	ENOG4105F8V	Hydrolase, tatD family
CAY59_16590	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
CAY59_16595	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
CAY59_16600	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CAY59_16605	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CAY59_16610	ENOG4105JC1	sterol-binding domain protein
CAY59_16630	ENOG4105BZU	Histidine kinase
CAY59_16635	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
CAY59_16655	ENOG4105CBX	hi0933 family
CAY59_16670	ENOG4107XZC	Restriction modification system DNA (Specificity
CAY59_16755	ENOG4107XZC	Restriction modification system DNA (Specificity
CAY59_16785	ENOG4105UYK	outer membrane protein a
CAY59_16790	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAY59_16795	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CAY59_16800	ENOG4108WC9	type VI secretion system effector, hcp1 family
CAY59_16805	ENOG4105CS6	Rhs element vgr protein
CAY59_16830	ENOG4105D9P	serine threonine protein kinase
CAY59_16860	ENOG4105EW9	transcriptional regulator AsnC family
CAY59_16935	ENOG4105D05	Receptor
CAY59_16945	ENOG4105BZU	Histidine kinase
CAY59_16950	ENOG4105BZU	Histidine kinase
CAY59_16955	ENOG4105BZU	Histidine kinase
CAY59_16960	ENOG4108WQH	regulatoR
CAY59_16965	ENOG4105BZU	Histidine kinase
CAY59_16975	ENOG4108WQH	regulatoR
CAY59_16980	ENOG4108TVJ	Nitroreductase
CAY59_16990	ENOG4107R88	Chemotaxis protein (CheV)
CAY59_16995	ENOG4108VAU	general secretion pathway protein G
CAY59_17005	ENOG4105FR1	rard protein
CAY59_17020	ENOG4106CKV	Pap2 superfamily protein
CAY59_17040	ENOG4105KPY	Small multidrug resistance protein
CAY59_17065	ENOG4107RGH	Aldehyde dehydrogenase
CAY59_17075	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CAY59_17080	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
CAY59_17090	ENOG4105CBC	glutamate synthase
CAY59_17105	ENOG4105EXC	Acyl-transferase
CAY59_17115	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CAY59_17120	ENOG4108UYE	Lactoylglutathione lyase
CAY59_17150	ENOG4105D9P	serine threonine protein kinase
CAY59_17170	ENOG4106VK6	Flagellar motor protein
CAY59_17185	ENOG4108ZF3	Phosphatase
CAY59_17240	ENOG4105CS6	Rhs element vgr protein
CAY59_17255	ENOG4107TV1	YD repeat protein
CAY59_17275	ENOG4107RFY	SbcCD D subunit
CAY59_17280	ENOG4105EYH	Exonuclease
CAY59_17290	ENOG4105E03	chitinase
CAY59_17320	ENOG4105QNF	Outer membrane lipoprotein
CAY59_17330	ENOG4105C2C	drug resistance transporter, Bcr CflA
CAY59_17340	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
CAY59_17350	ENOG4105C5W	Aldolase
CAY59_17360	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
CAY59_17365	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
CAY59_17380	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
CAY59_17385	ENOG4105CBN	LysR family transcriptional regulator
CAY59_17400	ENOG4107ZQN	disulfide bond
CAY59_17475	ENOG41064RH	membrane protein YliF
CAY59_17485	ENOG4107QZF	nitrite reductase NADPH large subunit
CAY59_17490	ENOG4105WZK	nitrite reductase NADPH small subunit
CAY59_17495	ENOG4105TMB	Formate nitrite transporter
CAY59_17500	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CAY59_17515	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
CAY59_17535	ENOG4105VXR	cytoplasmic protein
CAY59_17540	ENOG4107QI1	Mate efflux family protein
CAY59_17550	ENOG4108ISG	Major Facilitator
CAY59_17555	ENOG4105K63	Thioredoxin
CAY59_17560	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CAY59_17585	ENOG4105EFX	secretion protein, HlyD family
CAY59_17605	ENOG4105EIP	mannose-6-phosphate isomerase
CAY59_17615	ENOG4105BZU	Histidine kinase
CAY59_17620	ENOG4108KX4	response regulator
CAY59_17625	ENOG4105CXY	transporter
CAY59_17685	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
CAY59_17690	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
CAY59_17695	ENOG4107QI1	Mate efflux family protein
CAY59_17700	ENOG4105ECQ	AraC Family Transcriptional Regulator
CAY59_17705	ENOG4105CGF	Aromatic amino acid aminotransferase
CAY59_17720	ENOG4105WXI	Bacterial OB fold (BOF) protein
CAY59_17725	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CAY59_17730	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CAY59_17735	ENOG4105E0C	molybdate abc transporter
CAY59_17740	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
CAY59_17755	ENOG4105BZU	Histidine kinase
CAY59_17770	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CAY59_17775	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CAY59_17890	ENOG4108ZJT	translation initiation factor, Sui1
CAY59_17900	ENOG4105CPF	Cell wall formation (By similarity)
CAY59_17910	ENOG4105CD5	CoA-binding domain protein
CAY59_17915	ENOG4105CWB	LysR family transcriptional Regulator
CAY59_17925	ENOG4105CMR	udp-glucose 4-epimerase
CAY59_17935	ENOG4105E7W	lamb ycsf family protein
CAY59_17940	ENOG4105P4J	Allophanate hydrolase, subunit 1
CAY59_17955	ENOG4105CV6	ABC transporter, permease
CAY59_17960	ENOG4108I0Y	(ABC) transporter
CAY59_17970	ENOG4105RKW	reductase (By
CAY59_17975	ENOG4105BZU	Histidine kinase
CAY59_17985	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CAY59_18020	ENOG4105KA0	thioesterase Superfamily protein
CAY59_18025	ENOG4105D0M	Protease HtpX homolog
CAY59_18035	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CAY59_18040	ENOG4108M0H	Extracellular lipase
CAY59_18055	ENOG4105C3R	Methionine synthase
CAY59_18065	ENOG4105DU1	integral membrane protein, terc
CAY59_18070	ENOG4105CGH	5'-nucleotidase
CAY59_18075	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
CAY59_18080	ENOG4108UQ5	membrane protein YcdZ
CAY59_18085	ENOG4105DUM	transcriptional regulator, lysR family
CAY59_18095	ENOG4105TMB	Formate nitrite transporter
CAY59_18100	ENOG4108YYC	ycei family
CAY59_18105	ENOG4105DS1	cytochrome b561
CAY59_18120	ENOG4108M8H	domain protein
CAY59_18125	ENOG4105C1J	atp-dependent rna helicase
CAY59_18130	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
CAY59_18135	ENOG4108N3W	hemolysin secretion protein
CAY59_18140	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CAY59_18145	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CAY59_18160	ENOG4107RE1	Inosine-guanosine kinase
CAY59_18165	ENOG4105CKU	formyltetrahydrofolate synthetase
CAY59_18170	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CAY59_18180	ENOG4105CF7	AraC family transcriptional regulator
CAY59_18185	ENOG4108I6A	alcohol dehydrogenase
CAY59_18195	ENOG4105CDA	abc transporter atp-binding protein
CAY59_18200	ENOG4105E5Q	amino acid AbC transporter
CAY59_18205	ENOG4106TNF	Periplasmic binding protein
CAY59_18215	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
CAY59_18230	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
CAY59_18235	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
CAY59_18240	ENOG4105DE4	1-phosphofructokinase
CAY59_18245	ENOG4105DM4	PTS System
CAY59_18265	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CAY59_18275	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CAY59_18285	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CAY59_18290	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CAY59_18295	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CAY59_18360	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
CAY59_18370	ENOG4105KVH	Transcriptional regulator
CAY59_18380	ENOG4105C4X	radical SAM domain protein
CAY59_18385	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
CAY59_18390	ENOG4105ENH	Sulfatase
CAY59_18410	ENOG4105CR8	Transcriptional regulator
CAY59_18435	ENOG4105BZ1	(ABC) transporter
CAY59_18465	ENOG4105E09	nadh pyrophosphatase
CAY59_18480	ENOG4105C2C	drug resistance transporter, Bcr CflA
CAY59_18560	ENOG4105BZU	Histidine kinase
CAY59_18565	ENOG4105IPI	Membrane
CAY59_18605	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CAY59_18620	ENOG4105F8J	Adenylate Guanylate cyclase
CAY59_18635	ENOG4108IG5	Transcriptional regulator
CAY59_18650	ENOG4107QZF	nitrite reductase NADPH large subunit
CAY59_18655	ENOG4105D7T	ABC transporter
CAY59_18660	ENOG4105DG7	nitrate ABC transporter
CAY59_18700	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
CAY59_18705	ENOG4105BZU	Histidine kinase
CAY59_18710	ENOG4105C44	Serine transporter
CAY59_18715	ENOG4105BZU	Histidine kinase
CAY59_18735	ENOG4105G6Z	alkaline phosphatase
CAY59_18750	ENOG4105ETX	regulatoR
CAY59_18790	ENOG4105R8A	Heat shock protein
CAY59_18805	ENOG4107RUY	(E1 component), alpha subunit
CAY59_18810	ENOG4105CPP	Dehydrogenase, E1 component
CAY59_18815	ENOG4107QSN	dihydrolipoamide acetyltransferase
CAY59_18820	ENOG4105C10	Electron transfer flavoprotein
CAY59_18825	ENOG4105BZJ	Electron transfer flavoprotein
CAY59_18830	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
CAY59_18835	ENOG4105BZU	Histidine kinase
CAY59_18850	ENOG4105DUM	transcriptional regulator, lysR family
CAY59_18860	ENOG4105DMR	ABC, transporter
CAY59_18865	ENOG4105GBT	ABC transporter
CAY59_18870	ENOG4106PMH	Extracellular solute-binding protein family 3
CAY59_18875	ENOG4105E5Z	arginine transporter ATP-binding subunit
CAY59_18935	ENOG4105C26	Dehydrogenase
CAY59_18945	ENOG4105DUM	transcriptional regulator, lysR family
CAY59_18950	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CAY59_18960	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CAY59_18965	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
CAY59_18970	ENOG4105CCU	oxidase (Subunit III)
CAY59_18975	ENOG4105BZ9	Cytochrome C oxidase, subunit I
CAY59_18980	ENOG4105E2S	oxidase) subunit II
CAY59_18990	ENOG4105CHR	reductase
CAY59_18995	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CAY59_19000	ENOG4105E39	Enoyl-CoA hydratase
CAY59_19005	ENOG4105E39	Enoyl-CoA hydratase
CAY59_19015	ENOG4105C26	Dehydrogenase
CAY59_19020	ENOG4105CHU	acetyl-coa acetyltransferase
CAY59_19030	ENOG4105C1G	acyl-Coa dehydrogenase
CAY59_19035	ENOG4107QX3	carboxylase
CAY59_19040	ENOG4105E39	Enoyl-CoA hydratase
CAY59_19045	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
CAY59_19080	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
CAY59_19095	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CAY59_19100	ENOG4105BZU	Histidine kinase
CAY59_19105	ENOG4105C1J	atp-dependent rna helicase
CAY59_19125	ENOG4107S17	Phosphate-binding protein
CAY59_19140	ENOG4105DKW	ABC transporter
CAY59_19145	ENOG4105CXC	rtn protein
CAY59_19165	ENOG4105C1J	atp-dependent rna helicase
CAY59_19170	ENOG4105BZU	Histidine kinase
CAY59_19175	ENOG4105CKI	cobalamin synthesis protein
CAY59_19185	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
CAY59_19205	ENOG4105VRT	cytoplasmic protein
CAY59_19230	ENOG41090A4	Pterin carbinolamine dehydratase
CAY59_19235	ENOG4105MIR	Phenylalanine 4-monooxygenase
CAY59_19245	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CAY59_19250	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CAY59_19270	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
CAY59_19275	ENOG4105C0A	alcohol dehydrogenase
CAY59_19285	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
CAY59_19295	ENOG4108RMU	ferritin dps family protein
CAY59_19300	ENOG4108N3W	hemolysin secretion protein
CAY59_19310	ENOG4107R39	(ABC) transporter
CAY59_19330	ENOG4105BZU	Histidine kinase
CAY59_19345	ENOG4105VEQ	Cold shock protein
CAY59_19365	ENOG4105CDV	Ompa motb domain protein
CAY59_19375	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CAY59_19380	ENOG4107VXZ	Hydrolase
CAY59_19385	ENOG4108YZN	class I peptide chain release factor
CAY59_19410	ENOG4107YWA	deoxycytidylate deaminase
CAY59_19415	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
CAY59_19430	ENOG4105WH1	Two component transcriptional regulator luxr family
CAY59_19460	ENOG4105CUW	cytochrome C-TYPE protein
CAY59_19470	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
CAY59_19480	ENOG4105CHU	acetyl-coa acetyltransferase
CAY59_19500	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CAY59_19505	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CAY59_19535	ENOG4105EW9	transcriptional regulator AsnC family
CAY59_19550	ENOG4105BZU	Histidine kinase
CAY59_19560	ENOG4108QGH	periplasmic
CAY59_19565	ENOG41082IR	Excinuclease ABC C subunit domain protein
CAY59_19570	ENOG4108YXG	UPF0502 protein
CAY59_19580	ENOG41090HJ	UPF0265 protein
CAY59_19590	ENOG4105EE0	oxidoreductase
CAY59_19595	ENOG4105BZU	Histidine kinase
CAY59_19625	ENOG4105EW9	transcriptional regulator AsnC family
CAY59_19630	ENOG4105DVH	amino acid
CAY59_19645	ENOG4105E0F	Histidine kinase
CAY59_19650	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CAY59_19675	ENOG4105EFX	secretion protein, HlyD family
CAY59_19680	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CAY59_19685	ENOG4105CJW	magnesium transporter
CAY59_19690	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
CAY59_19695	ENOG4105DZC	cytosine deaminase
CAY59_19710	ENOG4105EST	Metal Dependent Phosphohydrolase
CAY59_19725	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
CAY59_19735	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CAY59_19755	ENOG4108Z33	Thiol disulfide Interchange Protein
CAY59_19770	ENOG4105EMU	Dehydrogenase
CAY59_19775	ENOG4107EXC	regulatoR
CAY59_19780	ENOG4105JJR	Histidine kinase
CAY59_19790	ENOG41080IJ	Diacylglycerol kinase
CAY59_19795	ENOG4105DIJ	Phosphoethanolamine transferase
CAY59_19805	ENOG4105EP9	oxidoreductase
CAY59_19810	ENOG4105ECQ	AraC Family Transcriptional Regulator
CAY59_19840	ENOG4105G2Y	Transcriptional regulator
CAY59_19845	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
CAY59_19850	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CAY59_19860	ENOG4105EJC	lysr family transcriptional regulator
CAY59_19890	ENOG4105JQN	Transcriptional regulator
CAY59_19905	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
CAY59_19910	ENOG4107R88	Chemotaxis protein (CheV)
CAY59_19925	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
CAY59_19930	ENOG41090JE	Utilization Protein
CAY59_19935	ENOG4105D4P	Coproporphyrinogen iii oxidase
CAY59_19940	ENOG4105WQ5	TonB family
CAY59_19945	ENOG41090AP	transport protein
CAY59_19950	ENOG4106GFD	transport protein
CAY59_19960	ENOG4105EHG	Permease protein
CAY59_19965	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CAY59_20005	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CAY59_20015	ENOG4105QVC	MOSC domain-containing protein
CAY59_20015	ENOG4105QVC	MOSC domain-containing protein
CAY59_20025	ENOG4105EKE	dihydroorotase
CAY59_20060	ENOG4105EG2	ABC transporter, permease
CAY59_20065	ENOG4105D56	permease protein
CAY59_20070	ENOG4107FKK	extracellular solute-binding protein family 1
CAY59_20080	ENOG4108IJ9	(ABC) transporter
CAY59_20160	ENOG4105V0I	UPF0267 protein
CAY59_20165	ENOG4108WUH	Transcriptional regulator, TetR family
CAY59_20170	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
CAY59_20180	ENOG4105CH6	catalase
CAY59_20185	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CAY59_20195	ENOG4105DM4	PTS System
CAY59_20200	ENOG4108YRF	PTS System
CAY59_20220	ENOG4105EIP	mannose-6-phosphate isomerase
CAY59_20230	ENOG4105DWP	Membrane
CAY59_20250	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
CAY59_20265	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
CAY59_20270	ENOG4105CK2	sodium dicarboxylate symporter
CAY59_20275	ENOG4105CEP	NADH dehydrogenase
CAY59_20290	ENOG4105CK1	PTS System
CAY59_20295	ENOG4105BZU	Histidine kinase
CAY59_20305	ENOG4105UYK	outer membrane protein a
CAY59_20325	ENOG4105UYK	outer membrane protein a
CAY59_20340	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CAY59_20345	ENOG4105CUX	Signal transduction histidine kinase
CAY59_20350	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CAY59_20355	ENOG4108UW5	maltose o-acetyltransferase
CAY59_20365	ENOG4108JJ6	Type I secretion system ATPase
CAY59_20375	ENOG41086KC	Transcriptional regulator
CAY59_20380	ENOG41086KC	Transcriptional regulator
CAY59_20390	ENOG4105C8Q	Methyl-accepting chemotaxis
CAY59_20410	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CAY59_20445	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CAY59_20450	ENOG4105E2Z	phosphate ABC transporter (Permease
CAY59_20455	ENOG4105C8U	phosphate abc transporter
CAY59_20460	ENOG4107S17	Phosphate-binding protein
CAY59_20485	ENOG4107ENK	receptor
CAY59_20490	ENOG4105CUG	Oligopeptidase b
CAY59_20495	ENOG4105C1J	atp-dependent rna helicase
CAY59_20505	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
CAY59_20510	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CAY59_20515	ENOG4108XDN	Transcriptional regulator
CAY59_20520	ENOG4107SEY	Conserved Protein
CAY59_20525	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
CAY59_20540	ENOG4106TD9	Diguanylate cyclase
CAY59_20550	ENOG4105KK7	inner membrane protein YiaW
CAY59_20555	ENOG4105EFX	secretion protein, HlyD family
CAY59_20560	ENOG4108V7D	UPF0397 protein
CAY59_20565	ENOG4108JJB	ABC transporter
CAY59_20595	ENOG4105GXZ	Ferredoxin-type protein NapH
CAY59_20600	ENOG4108BGM	Quinol dehydrogenase periplasmic component
CAY59_20605	ENOG4108MK9	spermidine N(1)-acetyltransferase
CAY59_20620	ENOG4105YE1	PilZ domain
CAY59_20625	ENOG4107QE9	Inherit from COG: Membrane
CAY59_20635	ENOG4105DAN	ATP-dependent protease
CAY59_20645	ENOG4108JQ5	ABC transporter
CAY59_20655	ENOG4105CC0	LysR family Transcriptional regulator
CAY59_20665	ENOG4105DMF	Dehydrogenase
CAY59_20675	ENOG4105D64	Mechanosensitive ion channel
CAY59_20685	ENOG4105CPQ	Dehydrogenase
CAY59_20690	ENOG4105FCD	Major Facilitator
CAY59_20695	ENOG4105BZU	Histidine kinase
CAY59_20720	ENOG4105CPQ	Dehydrogenase
CAY59_20815	ENOG4105IM0	capsid protein
CAY59_20835	ENOG4107DE1	head-to-tail joining protein
CAY59_20890	ENOG4108MXB	Protein of unknown function (DUF968)
CAY59_20915	ENOG4105CAR	Terminase, large subunit
CAY59_20950	ENOG4105D9P	serine threonine protein kinase
CAY59_20965	ENOG4108HJ1	Uncharacterized conserved protein (DUF2303)
CAY59_20985	ENOG4107R08	Integrase
CAY59_21000	ENOG4108UVJ	appr-1-p processing domain protein
CAY59_21025	ENOG4105CPQ	Dehydrogenase
CAY59_21030	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CAY59_21035	ENOG4105BZU	Histidine kinase
CAY59_21055	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CAY59_21075	ENOG4105EXG	Transcriptional regulator
CAY59_21080	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
CAY59_21100	ENOG41064T2	transcriptional regulator, lysR family
CAY59_21110	ENOG4107SSZ	Phosphatase
CAY59_21145	ENOG4108FZ9	Chaperone
CAY59_21155	ENOG4105CW0	outer membrane usher protein
CAY59_21160	ENOG4108VEV	chaperone
CAY59_21185	ENOG4105BZU	Histidine kinase
CAY59_21195	ENOG4108JIR	Flagellum-specific ATP synthase
CAY59_21205	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CAY59_21210	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CAY59_21220	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAY59_21235	ENOG4105DD5	Flagellar motor switch protein
CAY59_21240	ENOG4105CN7	Flagellar biosynthetic protein FliP
CAY59_21245	ENOG4105VS8	Flagellar biosynthetic protein fliq
CAY59_21250	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CAY59_21255	ENOG4105D00	flagellar biosynthetic protein flhB
CAY59_21270	ENOG4105I03	Flagellin
CAY59_21280	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
CAY59_21285	ENOG4105MQ3	flagellar protein FliS
CAY59_21310	ENOG4107RD7	Flagellar Motor Protein, MotA
CAY59_21315	ENOG4105ER2	Ompa motb domain protein
CAY59_21340	ENOG4108S58	Phenazine biosynthesis protein PhzF
CAY59_21345	ENOG4105KWG	Pfam:DUF1696
CAY59_21355	ENOG4105F87	Dehydratase
CAY59_21385	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CAY59_21395	ENOG4108KJ1	Trap dicarboxylate transporter, dctp subunit
CAY59_21400	ENOG4105CH2	amidohydrolase
CAY59_21415	ENOG4107RCH	Diaminopropionate ammonia-lyase
CAY59_21430	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
CAY59_21450	ENOG4105DTJ	flagellar hook-associated protein
CAY59_21455	ENOG4105E1Q	flagellar hook-associated protein
CAY59_21460	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
CAY59_21470	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CAY59_21475	ENOG4105CGA	flagellar basal-body rod protein FlgG
CAY59_21480	ENOG4108KPB	Flagellar basal-body rod protein FlgF
CAY59_21485	ENOG4105BZE	flagellar hook protein, FlgE
CAY59_21490	ENOG4105W00	Flagellar hook capping protein
CAY59_21495	ENOG4108ZC9	flagellar basal-body rod protein flgc
CAY59_21500	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
CAY59_21520	ENOG4105E9H	Lytic Murein transglycosylase
CAY59_21545	ENOG4105EJQ	L-serine dehydratase
CAY59_21550	ENOG4105DUX	Transporter
CAY59_21555	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
CAY59_21575	ENOG4105ETT	transcriptional Regulator, LysR family
CAY59_21590	ENOG4105CJP	fad dependent oxidoreductase
CAY59_21600	ENOG4108MJ5	VirK protein
CAY59_21620	ENOG4107RCV	ABC transporter, permease
CAY59_21640	ENOG4107STF	Involved in phosphonate degradation (By similarity)
CAY59_21645	ENOG4108JPW	Aminotransferase
CAY59_21650	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
CAY59_21655	ENOG4105ETE	Transcriptional regulator (LacI family
CAY59_21680	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CAY59_21710	ENOG4105PAD	Hydrolase
CAY59_21715	ENOG4105JQN	Transcriptional regulator
CAY59_21745	ENOG4108UKZ	OsmC family
CAY59_21750	ENOG4105E0X	reductase
CAY59_21765	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
CAY59_21770	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CAY59_21775	ENOG4106TD9	Diguanylate cyclase
CAY59_21790	ENOG4105BZU	Histidine kinase
CAY59_21815	ENOG4105D9N	nucleoside
CAY59_21835	ENOG4105C0F	tryptophanase EC 4.1.99.1
CAY59_21840	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CAY59_21855	ENOG4105D5U	fad dependent oxidoreductase
CAY59_21870	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
CAY59_21875	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAY59_21915	ENOG4108WAV	Transcriptional regulator
CAY59_21925	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CAY59_21930	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CAY59_21940	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
CAY59_21945	ENOG4105CYW	agmatinase
CAY59_21950	ENOG4105E5M	Multidrug resistance protein D
CAY59_21955	ENOG4105CUG	Oligopeptidase b
CAY59_21970	ENOG4105CC5	ABC transporter
CAY59_21975	ENOG4105DIK	(ABC) transporter
CAY59_21980	ENOG4105DSE	periplasmic solute binding protein
CAY59_22025	ENOG4109015	Biopolymer transport protein exbD tolR
CAY59_22050	ENOG410804D	Sensor Signal Transduction Histidine Kinase
CAY59_22055	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CAY59_22060	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
CAY59_22070	ENOG4105C5I	Dehydrogenase
CAY59_22075	ENOG4108YYI	Protein of unknown function (DUF2810)
CAY59_22125	ENOG4108TEM	pseudouridine methyltransferase
CAY59_22145	ENOG4105DWF	phosphomethylpyrimidine kinase
CAY59_22150	ENOG4108YI8	ABC transporter
CAY59_22155	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
CAY59_22160	ENOG4107Z6I	Thiamine biosynthesis protein
CAY59_22165	ENOG4105ETU	transcriptional activator (TenA
CAY59_22170	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
CAY59_22175	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CAY59_22180	ENOG4108WIQ	phosphoesterase PA-phosphatase related protein
CAY59_22185	ENOG4107QY8	reductase
CAY59_22190	ENOG4105CUW	cytochrome C-TYPE protein
CAY59_22200	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CAY59_22220	ENOG4108W0I	acetyltransferase
CAY59_22260	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CAY59_22265	ENOG4105BZW	Glycerate kinase
CAY59_22270	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
CAY59_22360	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
CAY59_22375	ENOG4107WCA	isomerase
CAY59_22395	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CAY59_22405	ENOG4105EIF	outer membrane protein W
CAY59_22410	ENOG4107W31	Pentapeptide repeat protein
CAY59_22425	ENOG4107QI1	Mate efflux family protein
CAY59_22440	ENOG410814C	multidrug resistance protein
CAY59_22450	ENOG4108M1A	Chitin-binding protein
CAY59_22455	ENOG4105EW9	transcriptional regulator AsnC family
CAY59_22495	ENOG4105CC0	LysR family Transcriptional regulator
CAY59_22530	ENOG4105KAF	membrAne
CAY59_22540	ENOG4105BZU	Histidine kinase
CAY59_22550	ENOG4108HCJ	Hydrolase
CAY59_22560	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CAY59_22565	ENOG4105D3G	Pseudouridine synthase
CAY59_22570	ENOG4105UQX	Mate efflux family protein
CAY59_22575	ENOG4107RV5	Glycosyl hydrolase family 3 N-terminal domain protein
CAY59_22580	ENOG4105ECQ	AraC Family Transcriptional Regulator
CAY59_22590	ENOG41060NJ	transcriptional regulator
CAY59_22600	ENOG4108JQ7	(ABC) transporter
CAY59_22605	ENOG4105C3U	ABC transporter
CAY59_22610	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CAY59_22620	ENOG4105DEF	Extracellular solute-binding protein, family 5
CAY59_22630	ENOG4105ETE	Transcriptional regulator (LacI family
CAY59_22635	ENOG4108IJ9	(ABC) transporter
CAY59_22645	ENOG4105DRS	transport system, permease
CAY59_22660	ENOG41060NJ	transcriptional regulator
CAY59_22670	ENOG4108K0B	C-di-gmp phosphodiesterase
CAY59_22680	ENOG4105NBK	UPF0345 protein
CAY59_22730	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CAY59_22735	ENOG4105D03	DNA-3-methyladenine glycosylase II
CAY59_22745	ENOG4108VGI	doxx family
CAY59_22765	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
CAY59_22775	ENOG4108UHE	carbonic anhydrase
CAY59_22795	ENOG4105NXH	GreA GreB family elongation factor
CAY59_22800	ENOG4105KME	endoribonuclease L-psp
CAY59_22815	ENOG4105CHH	sulfate transporter
CAY59_22835	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CAY59_22840	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
CAY59_22850	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
CAY59_22855	ENOG4105IY8	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CAY59_22860	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
CAY59_22865	ENOG4105CQM	Urea amidohydrolase subunit alpha
CAY59_22870	ENOG4105KI2	Urea amidohydrolase subunit beta
CAY59_22875	ENOG4108YZ9	Urea amidohydrolase subunit gamma
CAY59_22880	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CAY59_22895	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CAY59_22920	ENOG4105D6U	Sodium Glutamate Symporter
CAY59_22925	ENOG4107U9B	transcriptional regulator
CAY59_22930	ENOG4105CZV	ABC transporter
CAY59_22965	ENOG4105CHR	reductase
CAY59_22970	ENOG4105D6U	Sodium Glutamate Symporter
CAY59_22985	ENOG4105C8Q	Methyl-accepting chemotaxis
CAY59_22990	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CAY59_23000	ENOG4108VAC	response regulator
CAY59_23005	ENOG4108HRK	Histidine kinase
CAY59_23040	ENOG4105Y49	secretion protein, HlyD family
CAY59_23055	ENOG4105CNI	cell division protein FtsW
CAY59_23060	ENOG4105CDY	transcriptional regulatory protein
CAY59_23070	ENOG4105BZU	Histidine kinase
CAY59_23095	ENOG4108JQ7	(ABC) transporter
CAY59_23125	ENOG4106RMF	ParB family
CAY59_23130	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
CAY59_23145	ENOG4105EQ2	LysR family Transcriptional regulator
CAY59_23155	ENOG4105FCK	Membrane
CAY59_23160	ENOG4105C5Y	PTS System
CAY59_23165	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CAY59_23170	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
CAY59_23180	ENOG4108J59	Extracellular solute-binding protein, family 5
CAY59_23195	ENOG4108JJA	ABC, transporter
CAY59_23210	ENOG4107QZV	Type I secretion membrane fusion protein
CAY59_23215	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CAY59_23220	ENOG4105CQZ	Histidine kinase
CAY59_23225	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CAY59_23240	ENOG4105C26	Dehydrogenase
CAY59_23250	ENOG4105CK7	Sodium proline symporter
CAY59_23290	ENOG4105EW9	transcriptional regulator AsnC family
CAY59_23300	ENOG4105BZ1	(ABC) transporter
CAY59_23330	ENOG4105P66	Membrane
CAY59_23335	ENOG4108UHU	Aldolase
CAY59_23340	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
CAY59_23350	ENOG4105DEI	Mannitol dehydrogenase
CAY59_23355	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CAY59_23360	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
CAY59_23365	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CAY59_23370	ENOG4105C6F	GntR Family Transcriptional Regulator
CAY59_23375	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
CAY59_23380	ENOG4105EXG	Transcriptional regulator
CAY59_23395	ENOG4105C1J	atp-dependent rna helicase
CAY59_23400	ENOG4105RW8	MltA-interacting MipA family protein
CAY59_23410	ENOG4107YB6	acetyltransferase, (GNAT) family
CAY59_23415	ENOG4108RPX	mosc domain containing protein
CAY59_23430	ENOG4108TDH	Cell wall binding repeat 2-containing protein
CAY59_23435	ENOG4108XM1	transcriptional regulator AsnC family
CAY59_23445	ENOG4105F4I	Transcriptional regulator
CAY59_23455	ENOG4105C8Q	Methyl-accepting chemotaxis
CAY59_23480	ENOG4107FKK	extracellular solute-binding protein family 1
CAY59_23490	ENOG4105CG3	alpha amylase, catalytic region
CAY59_23495	ENOG4105C5Q	Transcriptional regulator
CAY59_23500	ENOG4105MVE	transcriptional regulator
CAY59_23505	ENOG4105ZXK	Dehydrogenase
CAY59_23520	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
CAY59_23525	ENOG4105C6Z	Gluconate
CAY59_23565	ENOG4108JU3	Alkyl hydroperoxide reductase
CAY59_23570	ENOG4105D3R	alkyl hydroperoxide reductase
CAY59_23575	ENOG4105K56	Transcriptional regulator
CAY59_23580	ENOG4108ZHJ	Organic hydroperoxide resistance protein
CAY59_23625	ENOG4108W2Y	isochorismatase
CAY59_23640	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
CAY59_23665	ENOG4105CFP	Peptidase U32
CAY59_23675	ENOG4105C8Q	Methyl-accepting chemotaxis
CAY59_23680	ENOG4107RAN	Peptidase, M16
CAY59_23700	ENOG4106KNT	transcriptional regulator
CAY59_23705	ENOG410863U	PTS System
CAY59_23710	ENOG4105C8I	hydrolase, family 38
CAY59_23720	ENOG4105DM4	PTS System
CAY59_23725	ENOG4105EIP	mannose-6-phosphate isomerase
CAY59_23745	ENOG4106PG1	outer membrane usher protein
CAY59_23750	ENOG4108FZ9	Chaperone
CAY59_23775	ENOG4105FDP	GntR family transcriptional regulator
CAY59_23785	ENOG4105C5Y	PTS System
CAY59_23790	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
CAY59_23795	ENOG4108UHU	Aldolase
CAY59_23810	ENOG4105DR5	peptidase
CAY59_23835	ENOG41062JF	Transcriptional regulator
CAY59_23840	ENOG4105E5M	Multidrug resistance protein D
CAY59_23850	ENOG4105ETE	Transcriptional regulator (LacI family
CAY59_23875	ENOG4105EJQ	L-serine dehydratase
CAY59_23885	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CAY59_23895	ENOG4105D5B	Sulfite reductase, subunit A
CAY59_23900	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CAY59_23905	ENOG4105BZU	Histidine kinase
CAY59_23915	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
CAY59_23935	ENOG4108K8S	endonuclease I
CAY59_23955	ENOG4105CXN	decarboxylase
CAY59_23960	ENOG4105D5Q	Arginine ornithine antiporter
CAY59_23970	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
CAY59_23985	ENOG4107QP7	CoA-transferase subunit A
CAY59_23990	ENOG4105CHU	acetyl-coa acetyltransferase
CAY59_24010	ENOG4107QNK	)-transporter
CAY59_24020	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
CAY59_24025	ENOG4105CIB	oxidoreductase Domain protein
CAY59_24030	ENOG4105EDK	PfkB domain protein
CAY59_24065	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CAY59_24095	ENOG41061ZR	Transcriptional regulator
CAY59_24105	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
CAY59_24110	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
CAY59_24115	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CAY59_24120	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
CAY59_24125	ENOG4107T9C	Alpha amylase catalytic region
CAY59_24140	ENOG41074DU	domain protein
CAY59_24145	ENOG4108P2H	Inner membrane protein YjiG
CAY59_24150	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CAY59_24160	ENOG4105CK2	sodium dicarboxylate symporter
CAY59_24195	ENOG4107ZF2	Phosphatase
CAY59_24200	ENOG4105DAY	polysaccharide export protein
CAY59_24215	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
CAY59_24220	ENOG4108NRW	Phospholipase, patatin family
CAY59_24235	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CAY59_24245	ENOG4105C72	UPF0176 protein
CAY59_24260	ENOG4105DZ1	carboxypeptidase
CAY59_24270	ENOG4105ETT	transcriptional Regulator, LysR family
CAY59_24275	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
CAY59_24285	ENOG4105DP0	ferredoxin-NADP reductase
CAY59_24300	ENOG41068P6	UPF0319 protein
CAY59_24305	ENOG4105IPI	Membrane
CAY59_24315	ENOG4105J12	Multidrug resistance protein mdtN
CAY59_24345	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
CAY59_24350	ENOG4105G2Y	Transcriptional regulator
CAY59_24355	ENOG4105CNH	Multidrug resistance protein MdtL
CAY59_24365	ENOG4105I4A	GCN5-related N-acetyltransferase
CAY59_24375	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CAY59_24380	ENOG4105EB3	Histidine kinase
CAY59_24395	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CAY59_24400	ENOG4105F1A	Pyruvate formate-lyase
CAY59_24405	ENOG4105C6N	Formate acetyltransferase
CAY59_24420	ENOG4105BZU	Histidine kinase
CAY59_24445	ENOG4105M4H	endoribonuclease L-psp
CAY59_24455	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CAY59_24460	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CAY59_24475	ENOG4105E18	UPF0276 protein
CAY59_24490	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
CAY59_24495	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
CAY59_24510	ENOG4105C5H	ABC transporter
CAY59_24515	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
CAY59_24530	ENOG4105HEI	LysR family (Transcriptional regulator
CAY59_24540	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
CAY59_24545	ENOG4105N14	lysine exporter protein LysE YggA
CAY59_24575	ENOG4105CGH	5'-nucleotidase
CAY59_24580	ENOG4105CWX	Alpha-1,2-mannosidase
CAY59_24585	ENOG4105CWX	Alpha-1,2-mannosidase
CAY59_24595	ENOG4105CWX	Alpha-1,2-mannosidase
CAY59_24600	ENOG4105CWX	Alpha-1,2-mannosidase
CAY59_24605	ENOG4105DM4	PTS System
CAY59_24615	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CAY59_24620	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
CAY59_24625	ENOG4105N2W	Transcriptional regulator
CAY59_24640	ENOG4105CH6	catalase
CAY59_24650	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CAY59_24665	ENOG4107RH7	Nicotinate phosphoribosyltransferase
CAY59_24680	ENOG4105RA2	Membrane
CAY59_24700	ENOG4105ETT	transcriptional Regulator, LysR family
CAY59_24705	ENOG4108M6U	Universal stress protein A
CAY59_24710	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CAY59_24725	ENOG4108IJ7	Glycine betaine
CAY59_24730	ENOG4108HQS	Glycine betaine
CAY59_24740	ENOG4105VYW	UPF0251 protein
CAY59_24760	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CAY59_24770	ENOG4107S8C	mandelate racemase muconate lactonizing
CAY59_24785	ENOG4108Z4X	TRANSCRIPTIONal
CAY59_24810	ENOG4107RZC	phospholipase d
CAY59_24820	ENOG4105BZS	acriflavin resistance protein
CAY59_24835	ENOG4105BZS	acriflavin resistance protein
CAY59_24845	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
CAY59_24855	ENOG4105CEY	Amp-dependent synthetase and ligase
CAY59_24870	ENOG41086KC	Transcriptional regulator
CAY59_24880	ENOG4105BZU	Histidine kinase
CAY59_24890	ENOG4105D6U	Sodium Glutamate Symporter
CAY59_24895	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
CAY59_24910	ENOG4107V40	secretion protein, HlyD family
CAY59_24915	ENOG4105HEI	LysR family (Transcriptional regulator
CAY59_24950	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CAY59_24955	ENOG4108S01	response regulator
CAY59_24970	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
CAY59_24975	ENOG4105HDK	L-asparaginase
CAY59_24980	ENOG4105BZU	Histidine kinase
CAY59_24990	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CAY59_24995	ENOG4105DUM	transcriptional regulator, lysR family
CAY59_25005	ENOG4105CGZ	zinc metallopeptidase
CAY59_25010	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
CAY59_25025	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CAY59_25035	ENOG4105CDW	Resistance protein
CAY59_25045	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CAY59_25065	ENOG4105HEI	LysR family (Transcriptional regulator
CAY59_25075	ENOG4105C1J	atp-dependent rna helicase
CAY59_25120	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CAY59_25145	ENOG4108P3C	
CAY59_25175	ENOG4105CHR	reductase
CAY59_25220	ENOG4105NAE	bifunctional deaminase-reductase domain protein
CAY59_25230	ENOG4105CYM	Glutathione S-transferase
CAY59_25235	ENOG4105C94	Transporter
CAY59_25240	ENOG4105DZ1	carboxypeptidase
CAY59_25250	ENOG4105DMQ	Methyltransferase
CAY59_25275	ENOG4105BZU	Histidine kinase
CAY59_25280	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CAY59_25295	ENOG4105VEQ	Cold shock protein
CAY59_25300	ENOG4105EUB	pirin domain protein
CAY59_25305	ENOG4108NRW	Phospholipase, patatin family
CAY59_25315	ENOG4105CD3	dihydroorotase
CAY59_25325	ENOG4105CKI	cobalamin synthesis protein
CAY59_25335	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
CAY59_25350	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CAY59_25355	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
CAY59_25360	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
CAY59_25375	ENOG4105E98	transcriptional regulator DeoR family
CAY59_25380	ENOG4108M6U	Universal stress protein A
CAY59_25390	ENOG4105C5H	ABC transporter
CAY59_25405	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CAY59_25415	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CAY59_25425	ENOG4108HK0	-acetyltransferase
CAY59_25430	ENOG4105CA0	peroxidase
CAY59_25445	ENOG4105M6F	mutator MutT protein
CAY59_25490	ENOG4108IJF	Heavy metal efflux pump, CzcA
CAY59_25515	ENOG4108IEG	Formate dehydrogenase Alpha subunit
CAY59_25535	ENOG4107QWP	ABC-2 type transporter
CAY59_25540	ENOG4105CJ1	ABC, transporter
CAY59_25550	ENOG4105C8Q	Methyl-accepting chemotaxis
CAY59_25575	ENOG4108IA2	Sodium pantothenate symporter
CAY59_25580	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
CAY59_25585	ENOG4108UHU	Aldolase
CAY59_25590	ENOG4105E2D	ec 3.2.1.52
CAY59_25595	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
CAY59_25605	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CAY59_25610	ENOG4108V1U	phospholipid-binding protein
CAY59_25625	ENOG4105D6J	arsenicaL-resistance protein
CAY59_25640	ENOG4105KVH	Transcriptional regulator
CAY59_25655	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
CAY59_25660	ENOG4105CTS	PTS system mannitol-specific
CAY59_25665	ENOG4105DXH	Alcohol dehydrogenase zinc-binding domain protein
CAY59_25700	ENOG4105E0U	tyrosine-specific transport protein
CAY59_25710	ENOG4105C8Q	Methyl-accepting chemotaxis
CAY59_25715	ENOG4105DWD	nucleoside recognition domain protein
CAY59_25735	ENOG4105DR5	peptidase
CAY59_25745	ENOG4105CR8	Transcriptional regulator
CAY59_25750	ENOG4105E5M	Multidrug resistance protein D
CAY59_25765	ENOG4108SXK	Transporter Drug Metabolite Exporter family
CAY59_25780	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
CAY59_25825	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
CAY59_25850	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
CAY59_25855	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CAY59_25860	ENOG4105UYK	outer membrane protein a
CAY59_25865	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CAY59_25870	ENOG4105DXI	Major Facilitator superfamily
CAY59_25885	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CAY59_25905	ENOG4105BZU	Histidine kinase
CAY59_25910	ENOG4105KHC	sulfurtransferase
CAY59_25930	ENOG4105ES1	acyl-CoA reductase
CAY59_25935	ENOG4108XDE	Acyl transferase is part of the fatty acid reductase system required for aldehyde biosynthesis
CAY59_25940	ENOG4108M8W	Monooxygenase
CAY59_25950	ENOG4107X8Z	Acyl-protein synthetase, LuxE
CAY59_25965	ENOG4105D06	uba thif-type nad fad binding protein
CAY59_25970	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CAY59_25975	ENOG4105EUJ	GTP cyclohydrolase i
CAY59_25985	ENOG4105C5A	transporter
CAY59_26010	ENOG4107RGM	aldo keto reductase
CAY59_26015	ENOG4108UNF	response regulator
CAY59_26025	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CAY59_26030	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CAY59_26045	ENOG4105ENX	hydrolase
CAY59_26055	ENOG4105EQ2	LysR family Transcriptional regulator
CAY59_26125	ENOG4108ZG0	Ompa motb domain protein
CAY59_26145	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CAY59_26155	ENOG4105BZU	Histidine kinase
CAY59_26160	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
CAY59_26165	ENOG4105C26	Dehydrogenase
CAY59_26170	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
CAY59_26180	ENOG4108HQS	Glycine betaine
CAY59_26190	ENOG4108RCM	Nitroreductase
CAY59_26195	ENOG4107QX8	SPFH domain, Band 7 family protein
CAY59_26215	ENOG4105BZU	Histidine kinase
CAY59_26220	ENOG4105CA0	peroxidase
CAY59_26225	ENOG4105BZU	Histidine kinase
CAY59_26270	ENOG4106W5V	Membrane
CAY59_26305	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CAY59_26310	ENOG4108K0B	C-di-gmp phosphodiesterase
CAY59_26315	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
CAY59_26320	ENOG4105C2J	ABC transporter
CAY59_26325	ENOG4105CNN	ABC, transporter
CAY59_26330	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CAY59_26335	ENOG4108RVA	ribokinase
CAY59_26340	ENOG4105ETE	Transcriptional regulator (LacI family
CAY59_26350	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
CAY59_26355	ENOG4108I5U	Uridine phosphorylase
CAY59_26375	ENOG4105DHS	permease protein
CAY59_26380	ENOG4105CM4	permease protein
CAY59_26385	ENOG4108IPW	abc transporter atp-binding protein
CAY59_26390	ENOG4108Z6Z	Transcriptional regulator
CAY59_26415	ENOG4105EM2	membrane
CAY59_26420	ENOG41088T4	Helicase IV
CAY59_26425	ENOG4108Z5K	methylglyoxal synthase
CAY59_26430	ENOG4108SV3	Tmao reductase system periplasmic protein tort
CAY59_26435	ENOG4105BZU	Histidine kinase
CAY59_26455	ENOG410804D	Sensor Signal Transduction Histidine Kinase
CAY59_26465	ENOG4105ENH	Sulfatase
CAY59_26470	ENOG4105ENH	Sulfatase
CAY59_26475	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
CAY59_26480	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CAY59_26515	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
CAY59_26520	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CAY59_26525	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
CAY59_26530	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CAY59_26535	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CAY59_26540	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CAY59_26545	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CAY59_26550	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CAY59_26555	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CAY59_26560	ENOG41064T2	transcriptional regulator, lysR family
CAY59_26565	ENOG4107TE5	Lipid kinase
CAY59_26570	ENOG4108YDI	single-species biofilm formation on inanimate substrate
CAY59_26590	ENOG4105C4X	radical SAM domain protein
CAY59_26600	ENOG4105F2V	VRR-NUC domain-containing protein
CAY59_26615	ENOG4105D0M	Protease HtpX homolog
CAY59_26620	ENOG4108V0P	LemA family
CAY59_26625	ENOG4105CEE	C4-dicarboxylate transporter
CAY59_26645	ENOG4108MGY	Histidine kinase
CAY59_26650	ENOG4107KBT	8-Amino-7-oxononanoate synthase
CAY59_26655	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
CAY59_26660	ENOG4105DR5	peptidase
CAY59_26695	ENOG4105CBX	hi0933 family
CAY59_26810	ENOG4107QHF	type ii secretion system protein e
CAY59_26910	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CAY59_27055	ENOG4106V8H	Nucleoid-associated protein
CAY59_27150	ENOG4105W5Q	DNA repair protein (RadC
CAY59_27165	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
CAY59_27195	ENOG4105CS6	Rhs element vgr protein
CAY59_27210	ENOG4105E6M	Sulphatase-modifying factor protein
CAY59_27390	ENOG4108IYH	Dna topoisomerase
CAY59_27615	ENOG4105D13	transposase
CAY59_27625	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
CAY59_27655	ENOG4107WZZ	SMC domain protein
CAY59_27720	ENOG4107U4J	modification
CAY59_27770	ENOG4105UYK	outer membrane protein a
CAY59_27775	ENOG4107VGF	ig domain protein group 2 domain protein
CAY59_27925	ENOG4105DR5	peptidase
CAY59_27935	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
CAY59_27965	ENOG4107VGF	ig domain protein group 2 domain protein
CAY59_27995	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CAY59_28005	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
CAY59_28060	ENOG4105RWF	major outer membrane protein OmpA
CAY59_28125	ENOG4105CVR	type I restriction-modification system
CAY59_28140	ENOG4105DZR	Type I site-specific deoxyribonuclease
CAY59_28310	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)