locus-tag	class	description
HB764_00025	COG2199	diguanylate cyclase activity
HB764_00030	COG0606	chelatase, subunit chli
HB764_00040	COG3978	acetolactate synthase activity
HB764_00045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HB764_00050	COG0129	dihydroxy-acid dehydratase activity
HB764_00060	COG0583	DNA-binding transcription factor activity
HB764_00065	COG2814	Major facilitator Superfamily
HB764_00070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB764_00075	COG0765	amino acid transport
HB764_00085	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HB764_00095	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HB764_00125	COG3312	ion transport
HB764_00130	COG1475	DNA binding
HB764_00135	COG1192	Involved in chromosome partitioning
HB764_00150	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HB764_00180	COG1126	abc transporter atp-binding protein
HB764_00200	COG0592	DNA-directed DNA polymerase activity
HB764_00210	COG0187	DNA topoisomerase II activity
HB764_00215	COG0071	Belongs to the small heat shock protein (HSP20) family
HB764_00220	COG3977	Valine--pyruvate aminotransferase
HB764_00235	COG2119	membrane
HB764_00260	COG0604	alcohol dehydrogenase
HB764_00265	COG0183	Belongs to the thiolase family
HB764_00275	COG1739	Uncharacterized protein family UPF0029
HB764_00280	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HB764_00325	COG0583	DNA-binding transcription factor activity
HB764_00330	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HB764_00335	COG2960	long-chain fatty acid transporting porin activity
HB764_00340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB764_00345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB764_00390	COG0546	phosphoglycolate phosphatase activity
HB764_00395	COG4172	Belongs to the ABC transporter superfamily
HB764_00405	COG0601	transmembrane transport
HB764_00410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB764_00440	COG0515	serine threonine protein kinase
HB764_00455	COG0800	Aldolase
HB764_00460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB764_00470	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HB764_00480	COG1522	sequence-specific DNA binding
HB764_00485	COG5002	protein histidine kinase activity
HB764_00485	COG5001	Diguanylate cyclase
HB764_00505	COG0589	response to stress
HB764_00510	COG1528	Iron-storage protein
HB764_00520	COG2081	HI0933 family
HB764_00540	COG1910	domain protein
HB764_00555	COG1322	Protein conserved in bacteria
HB764_00565	COG3165	ubiquinone biosynthetic process from chorismate
HB764_00580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HB764_00585	COG0805	protein transport
HB764_00590	COG0084	hydrolase, TatD family'
HB764_00605	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HB764_00605	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HB764_00610	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HB764_00640	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HB764_00650	COG2204	response regulator
HB764_00655	COG3852	Histidine kinase
HB764_00665	COG0174	glutamine synthetase
HB764_00670	COG1217	gtp-binding protein TYPA
HB764_00690	COG1490	D-aminoacyl-tRNA deacylase activity
HB764_00695	COG0456	acetyltransferase
HB764_00715	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HB764_00720	COG3031	protein transport across the cell outer membrane
HB764_00730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB764_00735	COG1459	type II secretion system
HB764_00740	COG2165	general secretion pathway protein
HB764_00745	COG2165	general secretion pathway protein
HB764_00750	COG2165	general secretion pathway protein
HB764_00755	COG4795	General secretion pathway protein
HB764_00760	COG3156	type II secretion system protein K
HB764_00765	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HB764_00770	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HB764_00780	COG1218	3'(2'),5'-bisphosphate nucleotidase
HB764_00785	COG0494	nUDIX hydrolase
HB764_00795	COG1040	competence protein
HB764_00810	COG2183	response to ionizing radiation
HB764_00820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB764_00835	COG2233	PERMEase
HB764_00840	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HB764_00845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB764_00850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HB764_00855	COG1758	RNA polymerase activity
HB764_00860	COG0194	GDP metabolic process
HB764_00875	COG0848	biopolymer transport protein
HB764_00880	COG0811	peptide transport
HB764_00900	COG4174	ABC transporter (Permease)
HB764_00905	COG4239	(ABC) transporter, permease
HB764_00910	COG0747	negative chemotaxis
HB764_00915	COG0444	Belongs to the ABC transporter superfamily
HB764_00920	COG4608	Belongs to the ABC transporter superfamily
HB764_00935	COG2246	polysaccharide biosynthetic process
HB764_00945	COG1561	YicC-like family, N-terminal region
HB764_00950	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HB764_00955	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HB764_00960	COG1560	Kdo2-lipid A biosynthetic process
HB764_00970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HB764_01005	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HB764_01020	COG0463	Glycosyl transferase, family 2
HB764_01025	COG0859	PFAM glycosyl transferase family 9
HB764_01030	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HB764_01035	COG3642	lipopolysaccharide core region biosynthetic process
HB764_01045	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HB764_01085	COG1519	Transferase
HB764_01090	COG0859	PFAM glycosyl transferase family 9
HB764_01100	COG1560	Kdo2-lipid A biosynthetic process
HB764_01110	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB764_01155	COG0463	Glycosyl transferase, family 2
HB764_01160	COG1215	transferase activity, transferring glycosyl groups
HB764_01165	COG1215	transferase activity, transferring glycosyl groups
HB764_01175	COG0438	transferase activity, transferring glycosyl groups
HB764_01195	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB764_01200	COG1459	type II secretion system
HB764_01205	COG2165	general secretion pathway protein
HB764_01255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HB764_01290	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HB764_01295	COG0110	maltose O-acetyltransferase activity
HB764_01300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HB764_01315	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HB764_01320	COG0149	triose-phosphate isomerase activity
HB764_01350	COG1494	fructose-1,6-bisphosphatase
HB764_01360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HB764_01365	COG1575	Belongs to the MenA family. Type 1 subfamily
HB764_01385	COG1609	Transcriptional regulator
HB764_01390	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HB764_01410	COG0088	Forms part of the polypeptide exit tunnel
HB764_01495	COG1841	ribosomal large subunit assembly
HB764_01505	COG0201	protein transport
HB764_01510	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HB764_01515	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HB764_01520	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HB764_01530	COG0202	RNA polymerase activity
HB764_01535	COG0203	ribosomal protein L17
HB764_01545	COG0545	Peptidyl-prolyl cis-trans isomerase
HB764_01570	COG2153	protein acetylation
HB764_01575	COG0513	Belongs to the DEAD box helicase family
HB764_01585	COG0737	Belongs to the 5'-nucleotidase family
HB764_01590	COG1648	precorrin-2 dehydrogenase activity
HB764_01590	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HB764_01605	COG3273	potassium ion transport
HB764_01605	COG0471	metal ion transport
HB764_01610	COG0529	Catalyzes the synthesis of activated sulfate
HB764_01630	COG1136	(ABC) transporter
HB764_01645	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HB764_01655	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB764_01665	COG2911	Protein conserved in bacteria
HB764_01670	COG2105	PFAM AIG2 family protein
HB764_01680	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HB764_01690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HB764_01695	COG0163	prenyltransferase activity
HB764_01700	COG4143	(ABC) transporter
HB764_01705	COG1178	ABC-type Fe3 transport system permease component
HB764_01710	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HB764_01725	COG2358	TRAP transporter, solute receptor (TAXI family
HB764_01745	COG0142	geranyltranstransferase activity
HB764_01750	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HB764_01765	COG2966	Psort location CytoplasmicMembrane, score
HB764_01770	COG3610	response to peptide
HB764_01795	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HB764_01800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB764_01805	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HB764_01810	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HB764_01830	COG0473	3-isopropylmalate dehydrogenase activity
HB764_01835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HB764_01855	COG0583	DNA-binding transcription factor activity
HB764_01860	COG1022	Amp-dependent synthetase and ligase
HB764_01865	COG0028	Belongs to the TPP enzyme family
HB764_01870	COG0440	acetolactate synthase activity
HB764_01875	COG3706	GGDEF domain
HB764_01885	COG0469	pyruvate kinase activity
HB764_01890	COG1349	DNA-binding transcription factor activity
HB764_01895	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HB764_01940	COG0358	DNA primase activity
HB764_01945	COG1610	YqeY-like protein
HB764_01950	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HB764_01955	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HB764_01960	COG0596	Alpha beta hydrolase
HB764_01970	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HB764_01975	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HB764_01990	COG3409	Peptidoglycan-binding domain 1 protein
HB764_01990	COG3267	Type II secretory pathway component ExeA
HB764_02000	COG4991	sh3 domain protein
HB764_02005	COG0306	phosphate transporter
HB764_02010	COG1392	Phosphate transport regulator
HB764_02015	COG3025	triphosphatase activity
HB764_02020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HB764_02030	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HB764_02040	COG1538	Outer membrane efflux protein
HB764_02045	COG0494	nUDIX hydrolase
HB764_02050	COG3151	Protein conserved in bacteria
HB764_02060	COG3150	esterase
HB764_02070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HB764_02075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HB764_02080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HB764_02085	COG3105	Protein conserved in bacteria
HB764_02090	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HB764_02105	COG0723	plastoquinol--plastocyanin reductase activity
HB764_02110	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HB764_02115	COG2857	Cytochrome c1
HB764_02120	COG0625	glutathione transferase activity
HB764_02125	COG2969	positive regulation of protein catabolic process
HB764_02130	COG2823	Periplasmic or secreted lipoprotein
HB764_02135	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HB764_02150	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HB764_02165	COG3116	cell division
HB764_02170	COG0768	penicillin binding
HB764_02175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HB764_02180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HB764_02195	COG0772	Belongs to the SEDS family
HB764_02210	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HB764_02215	COG0849	cell division
HB764_02220	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HB764_02240	COG0494	nUDIX hydrolase
HB764_02250	COG0505	Belongs to the CarA family
HB764_02255	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HB764_02260	COG0730	response to heat
HB764_02265	COG0583	DNA-binding transcription factor activity
HB764_02270	COG2860	membrane
HB764_02295	COG0493	'glutamate synthase
HB764_02300	COG0067	glutamate synthase
HB764_02300	COG0070	glutamate synthase
HB764_02300	COG0069	glutamate synthase activity
HB764_02310	COG0070	glutamate synthase
HB764_02310	COG0067	glutamate synthase
HB764_02310	COG0069	glutamate synthase activity
HB764_02315	COG1242	4 iron, 4 sulfur cluster binding
HB764_02320	COG2203	Gaf domain
HB764_02320	COG3706	GGDEF domain
HB764_02320	COG4251	negative regulation of phosphorylation
HB764_02320	COG5001	Diguanylate cyclase
HB764_02325	COG0784	Response regulator, receiver
HB764_02325	COG5002	protein histidine kinase activity
HB764_02325	COG2198	Histidine kinase
HB764_02335	COG0745	RESPONSE REGULATOR receiver
HB764_02345	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HB764_02360	COG0083	homoserine kinase activity
HB764_02365	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HB764_02395	COG1115	amino acid carrier protein
HB764_02400	COG3022	response to hydroperoxide
HB764_02410	COG0513	Belongs to the DEAD box helicase family
HB764_02425	COG0716	FMN binding
HB764_02430	COG4974	Belongs to the 'phage' integrase family
HB764_02435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB764_02440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HB764_02465	COG0667	Aldo Keto reductase
HB764_02490	COG0730	response to heat
HB764_02505	COG1283	sodium-dependent phosphate transmembrane transporter activity
HB764_02510	COG0583	DNA-binding transcription factor activity
HB764_02515	COG0640	Transcriptional regulator
HB764_02520	COG0268	Binds directly to 16S ribosomal RNA
HB764_02525	COG0728	peptidoglycan biosynthetic process
HB764_02530	COG0196	riboflavin kinase activity
HB764_02545	COG1047	Peptidyl-prolyl cis-trans
HB764_02550	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HB764_02555	COG3279	Response regulator of the LytR AlgR family
HB764_02560	COG3275	phosphorelay sensor kinase activity
HB764_02565	COG1966	Carbon starvation protein
HB764_02585	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HB764_02595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB764_02600	COG0287	Prephenate dehydrogenase
HB764_02600	COG1605	Chorismate mutase
HB764_02605	COG0739	heme binding
HB764_02615	COG0488	(ABC) transporter
HB764_02630	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
HB764_02635	COG1605	Chorismate mutase
HB764_02635	COG0077	Prephenate dehydratase
HB764_02640	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HB764_02645	COG0741	lytic transglycosylase activity
HB764_02650	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB764_02655	COG0564	pseudouridine synthase activity
HB764_02660	COG1496	oxidoreductase activity
HB764_02665	COG0542	response to heat
HB764_02720	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB764_02725	COG0826	peptidase U32
HB764_02735	COG0745	RESPONSE REGULATOR receiver
HB764_02740	COG5002	protein histidine kinase activity
HB764_02750	COG0248	Ppx GppA phosphatase
HB764_02755	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HB764_02760	COG0573	inorganic phosphate transmembrane transporter activity
HB764_02765	COG0581	inorganic phosphate transmembrane transporter activity
HB764_02770	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HB764_02775	COG0704	Plays a role in the regulation of phosphate uptake
HB764_02790	COG0450	alkyl hydroperoxide reductase
HB764_02795	COG0583	DNA-binding transcription factor activity
HB764_02800	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HB764_02810	COG0517	IMP dehydrogenase activity
HB764_02830	COG1862	Preprotein translocase
HB764_02835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB764_02840	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB764_02845	COG0483	inositol monophosphate 1-phosphatase activity
HB764_02850	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HB764_02865	COG0822	iron-sulfur transferase activity
HB764_02870	COG0316	Belongs to the HesB IscA family
HB764_02885	COG0633	Ferredoxin
HB764_02890	COG2975	iron-sulfur cluster assembly
HB764_02925	COG2976	Protein conserved in bacteria
HB764_02930	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB764_02945	COG2203	Gaf domain
HB764_02945	COG2199	diguanylate cyclase activity
HB764_02960	COG0516	GMP reductase activity
HB764_02960	COG0517	IMP dehydrogenase activity
HB764_02970	COG1757	Na H antiporter
HB764_02980	COG1584	GPR1 FUN34 yaaH family protein
HB764_02985	COG1115	amino acid carrier protein
HB764_02990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB764_02995	COG0583	DNA-binding transcription factor activity
HB764_03000	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HB764_03005	COG0668	transmembrane transport
HB764_03020	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HB764_03040	COG1289	transmembrane transporter activity
HB764_03045	COG0583	DNA-binding transcription factor activity
HB764_03080	COG2867	negative regulation of translational initiation
HB764_03085	COG2914	Belongs to the UPF0125 (RnfH) family
HB764_03090	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB764_03100	COG0497	DNA recombination
HB764_03115	COG1301	dicarboxylic acid transport
HB764_03120	COG0443	Heat shock 70 kDa protein
HB764_03155	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HB764_03160	COG0590	tRNA wobble adenosine to inosine editing
HB764_03170	COG0047	phosphoribosylformylglycinamidine synthase activity
HB764_03170	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HB764_03195	COG2195	Cleaves the N-terminal amino acid of tripeptides
HB764_03200	COG2252	PERMEase
HB764_03210	COG1073	alpha beta
HB764_03225	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HB764_03230	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HB764_03235	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HB764_03235	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HB764_03260	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HB764_03265	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HB764_03275	COG0142	geranyltranstransferase activity
HB764_03285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HB764_03300	COG0583	DNA-binding transcription factor activity
HB764_03310	COG2363	Small membrane protein
HB764_03325	COG1611	Belongs to the LOG family
HB764_03350	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
HB764_03365	COG1464	Belongs to the NlpA lipoprotein family
HB764_03370	COG2011	ABC-type metal ion transport system permease component
HB764_03375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HB764_03380	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HB764_03390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB764_03390	COG1263	PTS System
HB764_03395	COG0366	Alpha amylase catalytic
HB764_03400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HB764_03405	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HB764_03425	COG1686	Belongs to the peptidase S11 family
HB764_03430	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HB764_03435	COG0772	Belongs to the SEDS family
HB764_03440	COG0768	penicillin binding
HB764_03450	COG0799	negative regulation of ribosome biogenesis
HB764_03455	COG1466	dna polymerase III delta subunit
HB764_03460	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
HB764_03470	COG2888	peptidyl-tyrosine sulfation
HB764_03475	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HB764_03480	COG4535	Mg2 and Co2 transporter CorC
HB764_03490	COG1702	phosphate starvation-inducible protein PhoH
HB764_03500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB764_03620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HB764_03645	COG2890	protein-(glutamine-N5) methyltransferase activity
HB764_03650	COG3094	Invasion gene expression up-regulator, SirB
HB764_03655	COG2912	Transglutaminase-like superfamily
HB764_03665	COG0737	Belongs to the 5'-nucleotidase family
HB764_03670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HB764_03675	COG1187	pseudouridine synthase activity
HB764_03680	COG2840	Smr protein MutS2
HB764_03720	COG2608	mercury ion transmembrane transporter activity
HB764_03720	COG2217	Heavy metal translocating P-type atpase
HB764_03730	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HB764_03785	COG0784	Response regulator, receiver
HB764_03785	COG0835	chemotaxis
HB764_03790	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HB764_03795	COG1815	bacterial-type flagellum-dependent cell motility
HB764_03800	COG1558	bacterial-type flagellum-dependent cell motility
HB764_03810	COG1749	Flagellar hook protein flgE
HB764_03815	COG4787	bacterial-type flagellum-dependent cell motility
HB764_03825	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HB764_03830	COG1706	bacterial-type flagellum-dependent cell motility
HB764_03835	COG3951	Flagellar rod assembly protein muramidase FlgJ
HB764_03835	COG1705	Flagellar rod assembly protein muramidase FlgJ
HB764_03855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB764_03860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB764_03865	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB764_03870	COG2190	(PTS) system
HB764_03875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HB764_03880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB764_03885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HB764_03890	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
HB764_03930	COG0330	HflC and HflK could
HB764_03935	COG3118	belongs to the thioredoxin family
HB764_03940	COG0300	oxidoreductase activity
HB764_03945	COG1090	epimerase
HB764_03955	COG0622	Phosphoesterase
HB764_03975	COG3710	Transcriptional regulator
HB764_03990	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HB764_03995	COG3104	oligopeptide transport
HB764_04005	COG0367	asparagine synthase
HB764_04010	COG4651	solute:proton antiporter activity
HB764_04010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HB764_04015	COG1940	carbohydrate kinase activity
HB764_04015	COG1846	Transcriptional regulator
HB764_04020	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HB764_04025	COG2190	(PTS) system
HB764_04025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB764_04025	COG1263	PTS System
HB764_04035	COG0735	belongs to the Fur family
HB764_04055	COG0596	Alpha beta hydrolase
HB764_04060	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HB764_04065	COG0033	Phosphoglucomutase
HB764_04075	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HB764_04090	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HB764_04095	COG1053	succinate dehydrogenase
HB764_04105	COG0567	Dehydrogenase, E1 component
HB764_04110	COG0508	dehydrogenase complex catalyzes the overall conversion of
HB764_04125	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB764_04130	COG1121	(ABC) transporter
HB764_04135	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HB764_04140	COG4977	sequence-specific DNA binding
HB764_04145	COG1918	ferrous iron import across plasma membrane
HB764_04175	COG3102	Protein conserved in bacteria
HB764_04190	COG0788	formyltetrahydrofolate deformylase activity
HB764_04200	COG1199	ATP-dependent helicase activity
HB764_04205	COG1214	PFAM Peptidase M22, glycoprotease
HB764_04215	COG3065	identical protein binding
HB764_04220	COG2267	carboxylic ester hydrolase activity
HB764_04225	COG0318	PFAM AMP-dependent synthetase and ligase
HB764_04230	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HB764_04235	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HB764_04240	COG2894	cell division
HB764_04255	COG2951	lytic endotransglycosylase activity
HB764_04265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB764_04290	COG1028	Short-chain dehydrogenase reductase Sdr
HB764_04300	COG1169	isochorismate synthase
HB764_04305	COG1021	2,3-dihydroxybenzoate-AMP ligase
HB764_04310	COG1535	isochorismatase
HB764_04310	COG3433	isochorismatase activity
HB764_04315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB764_04315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB764_04325	COG2977	Belongs to the P-Pant transferase superfamily
HB764_04330	COG4771	TonB-dependent receptor
HB764_04340	COG0513	Belongs to the DEAD box helicase family
HB764_04345	COG0569	domain protein
HB764_04350	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HB764_04370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HB764_04375	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HB764_04380	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HB764_04420	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HB764_04425	COG0776	regulation of translation
HB764_04430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB764_04435	COG1555	photosystem II stabilization
HB764_04455	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HB764_04460	COG0436	Aminotransferase
HB764_04465	COG1169	isochorismate synthase
HB764_04475	COG0596	Alpha beta hydrolase
HB764_04480	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HB764_04495	COG2190	(PTS) system
HB764_04495	COG1263	PTS System
HB764_04495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB764_04500	COG0583	DNA-binding transcription factor activity
HB764_04510	COG2855	membrane
HB764_04565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB764_04585	COG1522	sequence-specific DNA binding
HB764_04590	COG1946	Acyl-CoA thioesterase
HB764_04595	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HB764_04610	COG3706	GGDEF domain
HB764_04645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB764_04650	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HB764_04655	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
HB764_04660	COG0516	GMP reductase activity
HB764_04660	COG0517	IMP dehydrogenase activity
HB764_04670	COG2217	Heavy metal translocating P-type atpase
HB764_04690	COG0537	adenosine 5'-monophosphoramidase activity
HB764_04720	COG1252	NADH dehydrogenase
HB764_04735	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HB764_04745	COG4591	ABC-type transport system involved in lipoprotein release permease component
HB764_04750	COG1136	(ABC) transporter
HB764_04755	COG4591	ABC-type transport system involved in lipoprotein release permease component
HB764_04765	COG2333	competence protein COMEC
HB764_04765	COG0658	competence protein
HB764_04770	COG1132	(ABC) transporter
HB764_04790	COG2719	SpoVR family
HB764_04795	COG2718	Belongs to the UPF0229 family
HB764_04800	COG2766	serine protein kinase
HB764_04815	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HB764_04825	COG1882	Formate acetyltransferase
HB764_04860	COG0708	Exodeoxyribonuclease III
HB764_04870	COG3923	Primosomal replication protein n
HB764_04875	COG0730	response to heat
HB764_04880	COG1199	ATP-dependent helicase activity
HB764_04890	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HB764_04895	COG1187	pseudouridine synthase activity
HB764_04905	COG1278	Cold shock
HB764_04915	COG0542	response to heat
HB764_04920	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HB764_04950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HB764_04955	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HB764_04960	COG0297	glycogen (starch) synthase activity
HB764_04980	COG3070	regulator of competence-specific genes
HB764_04995	COG0745	RESPONSE REGULATOR receiver
HB764_05000	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HB764_05005	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB764_05015	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HB764_05020	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HB764_05040	COG0189	ligase activity
HB764_05040	COG4067	protein conserved in archaea
HB764_05055	COG1801	Protein of unknown function DUF72
HB764_05070	COG0840	transmembrane signaling receptor activity
HB764_05075	COG0632	four-way junction helicase activity
HB764_05085	COG1271	oxidase subunit
HB764_05090	COG1294	oxidase, subunit
HB764_05095	COG4890	Cyd operon protein YbgT
HB764_05105	COG0824	Thioesterase
HB764_05110	COG0811	peptide transport
HB764_05125	COG0823	Involved in the tonB-independent uptake of proteins
HB764_05130	COG2885	chlorophyll binding
HB764_05135	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HB764_05150	COG3766	membrane
HB764_05160	COG0754	glutathionylspermidine amidase activity
HB764_05170	COG2205	protein histidine kinase activity
HB764_05170	COG0784	Response regulator, receiver
HB764_05185	COG0582	viral genome integration into host DNA
HB764_05375	COG4669	(LipO)protein
HB764_05405	COG3177	Filamentation induced by cAMP protein fic
HB764_05415	COG0583	DNA-binding transcription factor activity
HB764_05420	COG4792	protein secretion
HB764_05425	COG4791	protein targeting
HB764_05430	COG4794	Type iii secretion
HB764_05435	COG4790	Type iii secretion
HB764_05505	COG0457	Tetratricopeptide repeat
HB764_05560	COG2824	Alkylphosphonate utilization operon protein PhnA
HB764_05570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB764_05575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB764_05590	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HB764_05610	COG3568	Endonuclease Exonuclease Phosphatase
HB764_05625	COG4934	collagen metabolic process
HB764_05630	COG0402	S-adenosylhomocysteine deaminase activity
HB764_05655	COG0583	DNA-binding transcription factor activity
HB764_05665	COG0686	Belongs to the AlaDH PNT family
HB764_05675	COG1674	ftsk spoiiie
HB764_05685	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HB764_05695	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HB764_05715	COG2226	methyltransferase
HB764_05740	COG0300	oxidoreductase activity
HB764_05755	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HB764_05775	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HB764_05795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB764_05805	COG1757	Na H antiporter
HB764_05815	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HB764_05825	COG0131	Imidazoleglycerol-phosphate dehydratase
HB764_05825	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HB764_05830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HB764_05835	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HB764_05845	COG0140	phosphoribosyl-ATP diphosphatase activity
HB764_05845	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HB764_05850	COG3012	SEC-C Motif Domain Protein
HB764_05855	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HB764_05860	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HB764_05865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HB764_05870	COG0215	cysteine-tRNA ligase activity
HB764_05875	COG1435	thymidine kinase activity
HB764_05880	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HB764_05900	COG2116	formate transmembrane transporter activity
HB764_05910	COG0390	transport system, permease component
HB764_05915	COG4459	periplasmic nitrate reductase
HB764_05920	COG3005	denitrification pathway
HB764_05925	COG0243	molybdopterin cofactor binding
HB764_05940	COG1121	(ABC) transporter
HB764_05945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB764_05950	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB764_05955	COG1227	inorganic diphosphatase activity
HB764_05965	COG4172	Belongs to the ABC transporter superfamily
HB764_05975	COG4171	peptide transport system, permease
HB764_05980	COG4168	peptide transport system, permease
HB764_05990	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HB764_05995	COG1842	Phage shock protein A
HB764_06005	COG1983	PspC domain protein
HB764_06015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB764_06025	COG2818	Glycosylase
HB764_06045	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HB764_06050	COG0626	cystathionine gamma-synthase activity
HB764_06060	COG0733	neurotransmitter:sodium symporter activity
HB764_06065	COG0564	pseudouridine synthase activity
HB764_06075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB764_06080	COG1151	hydroxylamine reductase activity
HB764_06085	COG3604	Transcriptional regulator
HB764_06090	COG2814	Major facilitator Superfamily
HB764_06100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HB764_06105	COG4136	ATPase activity
HB764_06110	COG4135	transport system, permease component
HB764_06115	COG4134	Bacterial extracellular solute-binding protein
HB764_06125	COG0659	secondary active sulfate transmembrane transporter activity
HB764_06135	COG3313	Fe-S protein
HB764_06190	COG1061	Type III restriction enzyme res subunit
HB764_06195	COG1187	pseudouridine synthase activity
HB764_06200	COG2814	Major facilitator Superfamily
HB764_06210	COG0702	epimerase
HB764_06215	COG0534	Mate efflux family protein
HB764_06220	COG4181	ATPase activity
HB764_06250	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HB764_06260	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HB764_06270	COG1737	Transcriptional regulator
HB764_06275	COG0076	glutamate decarboxylase activity
HB764_06285	COG2431	L-lysine efflux transmembrane transporter activity
HB764_06295	COG3070	regulator of competence-specific genes
HB764_06310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB764_06310	COG4191	Histidine kinase
HB764_06320	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HB764_06350	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HB764_06355	COG4988	ABC transporter
HB764_06360	COG0492	ferredoxin-NADP+ reductase activity
HB764_06365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HB764_06380	COG3706	GGDEF domain
HB764_06385	COG0471	metal ion transport
HB764_06390	COG2949	membrane
HB764_06400	COG1643	Atp-dependent helicase
HB764_06460	COG0247	lactate metabolic process
HB764_06460	COG0277	FAD linked oxidase domain protein
HB764_06505	COG2986	histidine ammonia-lyase
HB764_06515	COG0010	Belongs to the arginase family
HB764_06525	COG2188	Transcriptional regulator
HB764_06570	COG0251	oxidation-reduction process
HB764_06620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HB764_06620	COG0072	phenylalanine-tRNA ligase activity
HB764_06625	COG1535	isochorismatase
HB764_06625	COG3433	isochorismatase activity
HB764_06630	COG1132	(ABC) transporter
HB764_06635	COG1132	(ABC) transporter
HB764_06635	COG2375	cellular response to nickel ion
HB764_06645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB764_06665	COG4774	siderophore transport
HB764_06670	COG4607	ABC-type enterochelin transport system periplasmic component
HB764_06675	COG4605	iron ion homeostasis
HB764_06680	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB764_06725	COG1346	cytolysis
HB764_06735	COG2925	Exonuclease
HB764_06745	COG1823	symporter activity
HB764_06750	COG0702	epimerase
HB764_06755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HB764_06765	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HB764_06775	COG2062	phosphohistidine phosphatase, SixA
HB764_06790	COG4139	cobalamin transport
HB764_06820	COG0583	DNA-binding transcription factor activity
HB764_06830	COG1451	nucleotide metabolic process
HB764_06915	COG2195	Cleaves the N-terminal amino acid of tripeptides
HB764_06930	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HB764_06940	COG0625	glutathione transferase activity
HB764_06950	COG0657	acetylesterase activity
HB764_07040	COG0519	Catalyzes the synthesis of GMP from XMP
HB764_07075	COG0494	nUDIX hydrolase
HB764_07115	COG0318	PFAM AMP-dependent synthetase and ligase
HB764_07135	COG3247	response to pH
HB764_07150	COG1846	Transcriptional regulator
HB764_07165	COG0693	protein deglycase activity
HB764_07180	COG2205	protein histidine kinase activity
HB764_07180	COG0784	Response regulator, receiver
HB764_07205	COG4999	Histidine kinase
HB764_07205	COG3850	Histidine kinase
HB764_07205	COG2205	protein histidine kinase activity
HB764_07205	COG3437	response regulator, receiver
HB764_07210	COG5001	Diguanylate cyclase
HB764_07210	COG3300	MHYT domain
HB764_07235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HB764_07240	COG1215	transferase activity, transferring glycosyl groups
HB764_07245	COG0438	transferase activity, transferring glycosyl groups
HB764_07275	COG0438	transferase activity, transferring glycosyl groups
HB764_07285	COG2204	response regulator
HB764_07305	COG2885	chlorophyll binding
HB764_07315	COG1793	dna ligase
HB764_07325	COG0534	Mate efflux family protein
HB764_07330	COG0307	riboflavin synthase, alpha
HB764_07340	COG3001	Fructosamine kinase
HB764_07345	COG2201	protein-glutamate methylesterase activity
HB764_07350	COG3706	GGDEF domain
HB764_07360	COG0791	NLP P60 protein
HB764_07365	COG0840	transmembrane signaling receptor activity
HB764_07410	COG3148	PFAM DTW domain containing protein
HB764_07415	COG1940	carbohydrate kinase activity
HB764_07425	COG0303	'Molybdopterin
HB764_07435	COG3842	ATPase activity
HB764_07440	COG4662	Binding-protein-dependent transport system inner membrane component
HB764_07450	COG2204	response regulator
HB764_07455	COG4191	Histidine kinase
HB764_07470	COG0488	(ABC) transporter
HB764_07475	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HB764_07495	COG3381	protein complex oligomerization
HB764_07505	COG0243	molybdopterin cofactor binding
HB764_07505	COG3383	formate dehydrogenase (NAD+) activity
HB764_07510	COG0437	4 iron, 4 sulfur cluster binding
HB764_07525	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HB764_07530	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HB764_07540	COG1177	transmembrane transport
HB764_07550	COG3842	ATPase activity
HB764_07575	COG0589	response to stress
HB764_07580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB764_07595	COG2217	Heavy metal translocating P-type atpase
HB764_07605	COG2010	Cytochrome c
HB764_07620	COG3278	Belongs to the heme-copper respiratory oxidase family
HB764_07695	COG4128	Pfam Zonular occludens toxin
HB764_07750	COG1067	ATP-dependent peptidase activity
HB764_07770	COG0488	(ABC) transporter
HB764_07795	COG2902	Dehydrogenase
HB764_07805	COG0308	aminopeptidase N
HB764_07820	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HB764_07825	COG1956	GAF domain-containing protein
HB764_07830	COG1132	(ABC) transporter
HB764_07835	COG2995	paraquat-inducible protein a
HB764_07840	COG3008	intermembrane lipid transfer
HB764_07865	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB764_07880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB764_07885	COG4597	amino acid ABC transporter
HB764_07890	COG0765	amino acid transport
HB764_07895	COG1126	abc transporter atp-binding protein
HB764_07900	COG0670	Belongs to the BI1 family
HB764_07905	COG2920	part of a sulfur-relay system
HB764_07910	COG1254	Belongs to the acylphosphatase family
HB764_07960	COG3706	GGDEF domain
HB764_07970	COG0602	queuosine metabolic process
HB764_07975	COG0561	phosphatase activity
HB764_08010	COG2828	Protein conserved in bacteria
HB764_08020	COG0372	Belongs to the citrate synthase family
HB764_08025	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HB764_08035	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HB764_08040	COG1030	water channel activity
HB764_08070	COG3772	lysozyme
HB764_08170	COG0242	peptide deformylase activity
HB764_08210	COG0517	IMP dehydrogenase activity
HB764_08210	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HB764_08265	COG0730	response to heat
HB764_08275	COG2358	TRAP transporter, solute receptor (TAXI family
HB764_08280	COG1012	belongs to the aldehyde dehydrogenase family
HB764_08285	COG3284	Transcriptional regulator
HB764_08295	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HB764_08300	COG0363	glucosamine-6-phosphate deaminase activity
HB764_08305	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HB764_08310	COG4565	transcriptional regulatory protein
HB764_08315	COG3290	protein histidine kinase activity
HB764_08335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB764_08375	COG0454	-acetyltransferase
HB764_08410	COG1280	lysine exporter protein (LysE YggA)
HB764_08420	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HB764_08425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HB764_08540	COG3227	Zinc metalloprotease (Elastase)
HB764_08545	COG1404	Belongs to the peptidase S8 family
HB764_08565	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB764_08585	COG0215	cysteine-tRNA ligase activity
HB764_08600	COG1368	sulfuric ester hydrolase activity
HB764_08625	COG1115	amino acid carrier protein
HB764_08655	COG1280	lysine exporter protein (LysE YggA)
HB764_08660	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HB764_08685	COG1280	lysine exporter protein (LysE YggA)
HB764_08725	COG3063	Type IV pilus biogenesis stability protein PilW
HB764_08750	COG1643	Atp-dependent helicase
HB764_08785	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HB764_08935	COG3227	Zinc metalloprotease (Elastase)
HB764_08965	COG3706	GGDEF domain
HB764_08975	COG0443	Heat shock 70 kDa protein
HB764_08980	COG0443	Heat shock 70 kDa protein
HB764_09000	COG1132	(ABC) transporter
HB764_09005	COG1132	(ABC) transporter
HB764_09025	COG0814	amino acid
HB764_09030	COG1454	alcohol dehydrogenase
HB764_09035	COG4221	oxidoreductase activity
HB764_09040	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HB764_09050	COG0861	Integral membrane protein TerC family
HB764_09060	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HB764_09065	COG1328	CTP reductase activity
HB764_09070	COG1280	lysine exporter protein (LysE YggA)
HB764_09115	COG3340	Belongs to the peptidase S51 family
HB764_09265	COG3209	COG3209 Rhs family protein
HB764_09295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB764_09310	COG3106	COG3106 Predicted ATPase
HB764_09325	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HB764_09330	COG0784	Response regulator, receiver
HB764_09330	COG2205	protein histidine kinase activity
HB764_09345	COG0814	amino acid
HB764_09350	COG1760	l-serine dehydratase
HB764_09370	COG2197	response regulator
HB764_09375	COG0720	synthase
HB764_09385	COG0017	Asparaginyl-tRNA synthetase
HB764_09400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB764_09425	COG1448	Aminotransferase
HB764_09445	COG0840	transmembrane signaling receptor activity
HB764_09450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB764_09455	COG1846	Transcriptional regulator
HB764_09480	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HB764_09495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HB764_09500	COG3108	Peptidase M15
HB764_09505	COG2989	Protein conserved in bacteria
HB764_09540	COG3088	subunit of a heme lyase
HB764_09540	COG4235	cytochrome complex assembly
HB764_09580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB764_09585	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB764_09595	COG1058	Belongs to the CinA family
HB764_09595	COG1546	Belongs to the CinA family
HB764_09610	COG0019	diaminopimelate decarboxylase activity
HB764_09650	COG0322	excinuclease ABC activity
HB764_09655	COG2197	response regulator
HB764_09660	COG0417	DNA replication proofreading
HB764_09680	COG1187	pseudouridine synthase activity
HB764_09690	COG0009	L-threonylcarbamoyladenylate synthase
HB764_09695	COG0613	PHP domain protein
HB764_09705	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HB764_09710	COG0512	Glutamine amidotransferase of anthranilate synthase
HB764_09720	COG0134	indole-3-glycerol-phosphate synthase activity
HB764_09720	COG0135	phosphoribosylanthranilate isomerase activity
HB764_09730	COG0159	tryptophan synthase activity
HB764_09735	COG1301	dicarboxylic acid transport
HB764_09760	COG2350	Protein conserved in bacteria
HB764_09795	COG1032	radical SAM domain protein
HB764_09870	COG2175	clavaminate synthase activity
HB764_09885	COG0840	transmembrane signaling receptor activity
HB764_09895	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HB764_09900	COG0463	Glycosyl transferase, family 2
HB764_09905	COG0745	RESPONSE REGULATOR receiver
HB764_09910	COG3850	Histidine kinase
HB764_09910	COG5002	protein histidine kinase activity
HB764_09960	COG3615	Tellurite resistance protein tehB
HB764_09970	COG3708	Transcriptional regulator
HB764_09970	COG2207	Transcriptional regulator
HB764_09980	COG1217	gtp-binding protein TYPA
HB764_09990	COG2176	DNA-directed DNA polymerase activity
HB764_10005	COG1136	(ABC) transporter
HB764_10005	COG0577	efflux transmembrane transporter activity
HB764_10010	COG1136	(ABC) transporter
HB764_10010	COG0577	efflux transmembrane transporter activity
HB764_10015	COG0577	efflux transmembrane transporter activity
HB764_10025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB764_10040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB764_10050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HB764_10060	COG3118	belongs to the thioredoxin family
HB764_10065	COG4232	protein-disulfide reductase activity
HB764_10080	COG2995	paraquat-inducible protein a
HB764_10085	COG3008	intermembrane lipid transfer
HB764_10085	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HB764_10090	COG3009	Protein conserved in bacteria
HB764_10105	COG4166	transmembrane transport
HB764_10115	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HB764_10120	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HB764_10130	COG0539	negative regulation of cytoplasmic translation
HB764_10140	COG0616	signal peptide processing
HB764_10145	COG1028	Short-chain dehydrogenase reductase Sdr
HB764_10165	COG0835	chemotaxis
HB764_10165	COG0784	Response regulator, receiver
HB764_10170	COG1940	carbohydrate kinase activity
HB764_10185	COG3710	Transcriptional regulator
HB764_10195	COG2272	Belongs to the type-B carboxylesterase lipase family
HB764_10220	COG4667	esterase of the alpha-beta hydrolase superfamily
HB764_10235	COG0733	neurotransmitter:sodium symporter activity
HB764_10250	COG1263	PTS System
HB764_10250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB764_10255	COG0084	hydrolase, TatD family'
HB764_10270	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HB764_10300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HB764_10315	COG1399	metal-binding, possibly nucleic acid-binding protein
HB764_10320	COG0424	maF-like protein
HB764_10325	COG0564	pseudouridine synthase activity
HB764_10330	COG1530	ribonuclease E activity
HB764_10335	COG0659	secondary active sulfate transmembrane transporter activity
HB764_10340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HB764_10345	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HB764_10375	COG2186	Transcriptional regulator
HB764_10385	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HB764_10390	COG0653	protein targeting
HB764_10395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HB764_10410	COG1122	ATPase activity
HB764_10415	COG4120	Belongs to the binding-protein-dependent transport system permease family
HB764_10435	COG0857	belongs to the CobB CobQ family
HB764_10435	COG0280	phosphate acetyltransferase
HB764_10440	COG0435	Glutathione S-transferase
HB764_10450	COG0444	Belongs to the ABC transporter superfamily
HB764_10455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB764_10460	COG0601	transmembrane transport
HB764_10470	COG0314	molybdopterin synthase activity
HB764_10475	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HB764_10485	COG0521	Mo-molybdopterin cofactor biosynthetic process
HB764_10490	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HB764_10495	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HB764_10510	COG0556	nucleotide-excision repair
HB764_10560	COG1882	Formate acetyltransferase
HB764_10565	COG4657	Part of a membrane complex involved in electron transport
HB764_10575	COG4656	Part of a membrane complex involved in electron transport
HB764_10580	COG4658	electron transport chain
HB764_10585	COG4659	FMN binding
HB764_10590	COG4660	Part of a membrane complex involved in electron transport
HB764_10595	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HB764_10600	COG0346	lactoylglutathione lyase activity
HB764_10610	COG2885	chlorophyll binding
HB764_10620	COG2056	Na+-H+ antiporter family
HB764_10635	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HB764_10650	COG1028	Short-chain dehydrogenase reductase Sdr
HB764_10655	COG1454	alcohol dehydrogenase
HB764_10655	COG1012	belongs to the aldehyde dehydrogenase family
HB764_10660	COG2095	MarC family integral membrane protein
HB764_10665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB764_10670	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HB764_10675	COG1757	Na H antiporter
HB764_10705	COG3083	sulfuric ester hydrolase activity
HB764_10720	COG4974	Belongs to the 'phage' integrase family
HB764_10770	COG4269	membrane
HB764_10780	COG0123	including yeast histone deacetylase and acetoin utilization protein
HB764_10795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HB764_10800	COG0778	Nitroreductase
HB764_10805	COG1902	pentaerythritol trinitrate reductase activity
HB764_10805	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB764_10810	COG0616	signal peptide processing
HB764_10815	COG0252	asparaginase activity
HB764_10820	COG3139	Protein of unknown function (DUF1315)
HB764_10830	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB764_10835	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HB764_10855	COG2226	methyltransferase
HB764_10875	COG1785	Belongs to the alkaline phosphatase family
HB764_10895	COG0668	transmembrane transport
HB764_10900	COG0076	glutamate decarboxylase activity
HB764_10905	COG2985	domain, Protein
HB764_10910	COG2261	transglycosylase associated protein
HB764_10920	COG2801	Transposase and inactivated derivatives
HB764_10990	COG4974	Belongs to the 'phage' integrase family
HB764_10995	COG2983	Belongs to the UPF0260 family
HB764_11005	COG2964	Protein conserved in bacteria
HB764_11015	COG0251	oxidation-reduction process
HB764_11020	COG0814	amino acid
HB764_11025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HB764_11030	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HB764_11040	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HB764_11050	COG2832	Protein of unknown function (DUF454)
HB764_11055	COG0745	RESPONSE REGULATOR receiver
HB764_11060	COG0583	DNA-binding transcription factor activity
HB764_11065	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HB764_11070	COG1286	toxin biosynthetic process
HB764_11075	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HB764_11080	COG0285	dihydrofolate synthase activity
HB764_11100	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HB764_11105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HB764_11110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HB764_11130	COG3101	peptidyl-lysine hydroxylation
HB764_11135	COG2860	membrane
HB764_11150	COG2890	protein-(glutamine-N5) methyltransferase activity
HB764_11160	COG2062	phosphohistidine phosphatase, SixA
HB764_11175	COG0183	Belongs to the thiolase family
HB764_11190	COG2067	long-chain fatty acid transport protein
HB764_11195	COG2067	long-chain fatty acid transport protein
HB764_11200	COG2853	Lipoprotein
HB764_11205	COG3088	subunit of a heme lyase
HB764_11205	COG4235	cytochrome complex assembly
HB764_11215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HB764_11220	COG1138	Cytochrome C-type biogenesis protein
HB764_11235	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HB764_11240	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HB764_11245	COG4133	protoheme IX ABC transporter activity
HB764_11255	COG0835	chemotaxis
HB764_11265	COG1192	Involved in chromosome partitioning
HB764_11270	COG2201	protein-glutamate methylesterase activity
HB764_11275	COG0643	Histidine kinase
HB764_11275	COG0784	Response regulator, receiver
HB764_11275	COG2198	Histidine kinase
HB764_11280	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HB764_11315	COG1684	flagellar biosynthetic protein fliR
HB764_11320	COG1987	bacterial-type flagellum assembly
HB764_11375	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HB764_11385	COG1677	Flagellar hook-basal body complex protein FliE
HB764_11405	COG1516	flagellar protein fliS
HB764_11415	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HB764_11420	COG1334	flagellar protein FlaG
HB764_11425	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB764_11430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB764_11435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB764_11440	COG2837	iron assimilation
HB764_11465	COG1393	Belongs to the ArsC family
HB764_11485	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HB764_11490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HB764_11495	COG2716	regulation of RNA biosynthetic process
HB764_11500	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HB764_11515	COG4783	chaperone-mediated protein folding
HB764_11520	COG1393	Belongs to the ArsC family
HB764_11540	COG2233	PERMEase
HB764_11545	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HB764_11550	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HB764_11555	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HB764_11560	COG0121	glutamine amidotransferase
HB764_11565	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HB764_11570	COG1960	acyl-CoA dehydrogenase activity
HB764_11595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HB764_11605	COG2226	methyltransferase
HB764_11615	COG0741	lytic transglycosylase activity
HB764_11615	COG1388	LysM domain
HB764_11630	COG0347	Belongs to the P(II) protein family
HB764_11650	COG0587	DNA-directed DNA polymerase activity
HB764_11675	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HB764_11680	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HB764_11690	COG0750	zinc metalloprotease
HB764_11700	COG0575	Belongs to the CDS family
HB764_11705	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HB764_11730	COG0024	Methionine aminopeptidase
HB764_11745	COG0564	pseudouridine synthase activity
HB764_11750	COG3098	single-species biofilm formation
HB764_11780	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HB764_11795	COG1720	tRNA m6t6A37 methyltransferase activity
HB764_11820	COG0733	neurotransmitter:sodium symporter activity
HB764_11835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB764_11840	COG0514	ATP-dependent DNA helicase (RecQ)
HB764_11845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HB764_11860	COG1477	protein flavinylation
HB764_11870	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HB764_11875	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HB764_11885	COG1805	sodium ion transport
HB764_11890	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HB764_11895	COG0271	Belongs to the BolA IbaG family
HB764_11925	COG1595	DNA-templated transcription, initiation
HB764_11945	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HB764_11950	COG0693	protein deglycase activity
HB764_11955	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HB764_11960	COG2166	iron-sulfur cluster assembly
HB764_11965	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HB764_11970	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HB764_11980	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HB764_11980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HB764_11990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HB764_11995	COG1074	ATP-dependent DNA helicase activity
HB764_12000	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HB764_12025	COG3141	response to X-ray
HB764_12040	COG2171	N-acyltransferase activity
HB764_12045	COG0584	glycerophosphoryl diester phosphodiesterase
HB764_12050	COG2271	Major facilitator Superfamily
HB764_12055	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HB764_12065	COG1349	DNA-binding transcription factor activity
HB764_12070	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HB764_12090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HB764_12095	COG0768	penicillin binding
HB764_12100	COG1609	Transcriptional regulator
HB764_12105	COG0583	DNA-binding transcription factor activity
HB764_12120	COG1022	Amp-dependent synthetase and ligase
HB764_12150	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HB764_12155	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HB764_12165	COG0560	Phosphoserine phosphatase
HB764_12175	COG0813	purine-nucleoside phosphorylase activity
HB764_12185	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HB764_12195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB764_12200	COG0084	hydrolase, TatD family'
HB764_12230	COG3153	acetyltransferase
HB764_12235	COG3154	lipid carrier protein
HB764_12245	COG0826	peptidase U32
HB764_12250	COG0826	peptidase U32
HB764_12255	COG0534	Mate efflux family protein
HB764_12275	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HB764_12295	COG0195	Participates in both transcription termination and antitermination
HB764_12315	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HB764_12330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HB764_12335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HB764_12345	COG1534	Rna-binding protein
HB764_12350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB764_12355	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HB764_12360	COG2027	D-alanyl-D-alanine carboxypeptidase
HB764_12375	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HB764_12380	COG0739	heme binding
HB764_12385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB764_12405	COG0628	permease
HB764_12415	COG0784	Response regulator, receiver
HB764_12415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB764_12415	COG2198	Histidine kinase
HB764_12415	COG2205	protein histidine kinase activity
HB764_12420	COG0747	negative chemotaxis
HB764_12430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB764_12435	COG0444	Belongs to the ABC transporter superfamily
HB764_12440	COG4608	Belongs to the ABC transporter superfamily
HB764_12450	COG2971	BadF BadG BcrA BcrD
HB764_12465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HB764_12470	COG3842	ATPase activity
HB764_12480	COG1840	ABC-type Fe3 transport system, periplasmic component
HB764_12485	COG0004	ammonium transporteR
HB764_12500	COG1049	propionate catabolic process, 2-methylcitrate cycle
HB764_12505	COG1752	Esterase of the alpha-beta hydrolase superfamily
HB764_12510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HB764_12515	COG1643	Atp-dependent helicase
HB764_12530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HB764_12540	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HB764_12555	COG1560	Kdo2-lipid A biosynthetic process
HB764_12560	COG0842	Transport permease protein
HB764_12565	COG1131	(ABC) transporter
HB764_12570	COG0659	secondary active sulfate transmembrane transporter activity
HB764_12575	COG0288	reversible hydration of carbon dioxide
HB764_12590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB764_12595	COG0508	dehydrogenase complex catalyzes the overall conversion of
HB764_12600	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HB764_12605	COG2186	Transcriptional regulator
HB764_12625	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB764_12630	COG1459	type II secretion system
HB764_12640	COG0237	dephospho-CoA kinase activity
HB764_12645	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HB764_12650	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HB764_12670	COG0228	four-way junction DNA binding
HB764_12675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HB764_12680	COG4137	Cytochrome C assembly protein
HB764_12685	COG4536	flavin adenine dinucleotide binding
HB764_12705	COG0612	Peptidase, M16
HB764_12710	COG1238	metal cluster binding
HB764_12720	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HB764_12725	COG0511	ligase activity, forming carbon-carbon bonds
HB764_12725	COG5016	pyruvate
HB764_12730	COG3630	sodium ion export across plasma membrane
HB764_12820	COG0527	aspartate kinase activity
HB764_12835	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HB764_12840	COG1546	Belongs to the CinA family
HB764_12850	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HB764_12880	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HB764_12890	COG0148	phosphopyruvate hydratase activity
HB764_12900	COG3956	TIGRFAM MazG family protein
HB764_12905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HB764_12925	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HB764_12930	COG1381	Involved in DNA repair and RecF pathway recombination
HB764_12935	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HB764_12955	COG3086	response to oxidative stress
HB764_12970	COG1595	DNA-templated transcription, initiation
HB764_12975	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HB764_12985	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HB764_13005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB764_13010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB764_13020	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HB764_13030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HB764_13040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HB764_13050	COG0583	DNA-binding transcription factor activity
HB764_13065	COG0668	transmembrane transport
HB764_13070	COG0191	fructose-bisphosphate aldolase activity
HB764_13090	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HB764_13110	COG2356	endonuclease I
HB764_13115	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HB764_13120	COG0189	ligase activity
HB764_13125	COG1678	Uncharacterized ACR, COG1678
HB764_13130	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HB764_13145	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HB764_13150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HB764_13155	COG0762	integral membrane protein
HB764_13170	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HB764_13175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HB764_13275	COG1012	belongs to the aldehyde dehydrogenase family
HB764_13325	COG1609	Transcriptional regulator
HB764_13335	COG1486	melibiose metabolic process
HB764_13340	COG1447	Phosphotransferase system cellobiose-specific component IIA
HB764_13385	COG1028	Short-chain dehydrogenase reductase Sdr
HB764_13395	COG0795	lipopolysaccharide-transporting ATPase activity
HB764_13400	COG0795	lipopolysaccharide-transporting ATPase activity
HB764_13410	COG2927	DNA polymerase III (CHI subunit)
HB764_13415	COG0525	valine-tRNA ligase activity
HB764_13425	COG0456	acetyltransferase
HB764_13465	COG0251	oxidation-reduction process
HB764_13470	COG0204	Acyl-transferase
HB764_13480	COG5007	Belongs to the BolA IbaG family
HB764_13490	COG2854	intermembrane phospholipid transfer
HB764_13495	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HB764_13500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HB764_13505	COG1127	ABC transporter
HB764_13515	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HB764_13515	COG0517	IMP dehydrogenase activity
HB764_13525	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HB764_13530	COG1137	ATPase activity
HB764_13540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HB764_13545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB764_13555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB764_13560	COG2239	Acts as a magnesium transporter
HB764_13565	COG0312	modulator of DNA gyrase
HB764_13575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HB764_13580	COG0564	pseudouridine synthase activity
HB764_13595	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HB764_13600	COG0312	modulator of DNA gyrase
HB764_13605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HB764_13610	COG3164	Protein of unknown function
HB764_13620	COG0424	maF-like protein
HB764_13625	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HB764_13630	COG1792	Involved in formation and maintenance of cell shape
HB764_13635	COG1077	Cell shape determining protein MreB Mrl
HB764_13680	COG1459	type II secretion system
HB764_13685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB764_13695	COG3409	Peptidoglycan-binding domain 1 protein
HB764_13695	COG3267	Type II secretory pathway component ExeA
HB764_13720	COG2199	diguanylate cyclase activity
HB764_13720	COG2200	EAL domain
HB764_13725	COG0629	single-stranded DNA binding
HB764_13740	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HB764_13750	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HB764_13755	COG0527	aspartate kinase activity
HB764_13760	COG0646	methionine synthase
HB764_13760	COG1410	methionine synthase
HB764_13825	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HB764_13845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HB764_13850	COG0735	belongs to the Fur family
HB764_13865	COG0432	Pfam Uncharacterised protein family UPF0047
HB764_13875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HB764_13880	COG0305	Participates in initiation and elongation during chromosome replication
HB764_13900	COG2965	DNA replication, synthesis of RNA primer
HB764_13910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HB764_13915	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HB764_13960	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HB764_13970	COG0678	peroxiredoxin activity
HB764_13970	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HB764_13975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB764_13990	COG0165	Argininosuccinate lyase
HB764_13990	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HB764_14005	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HB764_14015	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HB764_14025	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HB764_14030	COG0460	homoserine dehydrogenase
HB764_14030	COG0527	aspartate kinase activity
HB764_14035	COG0626	cystathionine gamma-synthase activity
HB764_14045	COG0281	malic enzyme
HB764_14055	COG2906	2 iron, 2 sulfur cluster binding
HB764_14065	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HB764_14080	COG2168	tRNA wobble position uridine thiolation
HB764_14085	COG2923	Belongs to the DsrF TusC family
HB764_14090	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HB764_14095	COG2964	Protein conserved in bacteria
HB764_14100	COG0545	Peptidyl-prolyl cis-trans isomerase
HB764_14115	COG1446	asparaginase
HB764_14120	COG1047	Peptidyl-prolyl cis-trans
HB764_14135	COG2249	NAD(P)H dehydrogenase (quinone) activity
HB764_14140	COG0488	(ABC) transporter
HB764_14150	COG0429	hydrolase of the alpha beta-hydrolase fold
HB764_14160	COG3954	Phosphoribulokinase
HB764_14165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB764_14185	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HB764_14190	COG0512	Glutamine amidotransferase of anthranilate synthase
HB764_14205	COG0546	phosphoglycolate phosphatase activity
HB764_14210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB764_14215	COG0557	exoribonuclease II activity
HB764_14225	COG1017	nitric oxide dioxygenase activity
HB764_14225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB764_14230	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HB764_14235	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HB764_14240	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HB764_14245	COG0330	HflC and HflK could
HB764_14250	COG0330	HflC and HflK could
HB764_14255	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HB764_14270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HB764_14275	COG0860	N-Acetylmuramoyl-L-alanine amidase
HB764_14280	COG0802	atpase or kinase
HB764_14285	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HB764_14365	COG1162	GTPase activity
HB764_14375	COG0471	metal ion transport
HB764_14390	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HB764_14395	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HB764_14410	COG1045	serine acetyltransferase
HB764_14415	COG4942	peptidase
HB764_14440	COG1053	succinate dehydrogenase
HB764_14445	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HB764_14475	COG1509	lysine 2,3-aminomutase activity
HB764_14500	COG0534	Mate efflux family protein
HB764_14510	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HB764_14520	COG0745	RESPONSE REGULATOR receiver
HB764_14525	COG2205	protein histidine kinase activity
HB764_14535	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HB764_14540	COG3030	protein affecting phage T7 exclusion by the F plasmid
HB764_14545	COG1027	Aspartate ammonia-lyase
HB764_14550	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HB764_14555	COG4232	protein-disulfide reductase activity
HB764_14565	COG2095	MarC family integral membrane protein
HB764_14575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HB764_14595	COG2205	protein histidine kinase activity
HB764_14595	COG0784	Response regulator, receiver
HB764_14600	COG2814	Major facilitator Superfamily
HB764_14615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HB764_14620	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HB764_14625	COG0511	ligase activity, forming carbon-carbon bonds
HB764_14630	COG0439	Biotin carboxylase
HB764_14640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HB764_14645	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HB764_14650	COG2199	diguanylate cyclase activity
HB764_14695	COG1982	Orn Lys Arg decarboxylase major
HB764_14700	COG0531	amino acid
HB764_14705	COG3710	Transcriptional regulator
HB764_14710	COG0789	Transcriptional regulator
HB764_14725	COG0151	Belongs to the GarS family
HB764_14740	COG1253	flavin adenine dinucleotide binding
HB764_14745	COG3068	Protein conserved in bacteria
HB764_14755	COG1573	uracil-dna glycosylase
HB764_14765	COG2816	NAD+ diphosphatase activity
HB764_14770	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HB764_14790	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HB764_14805	COG0250	Participates in transcription elongation, termination and antitermination
HB764_14810	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HB764_14850	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HB764_14860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HB764_14940	COG4206	TonB-dependent receptor
HB764_14960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB764_14965	COG0534	Mate efflux family protein
HB764_14980	COG2937	Belongs to the GPAT DAPAT family
HB764_14990	COG3161	chorismate lyase activity
HB764_14995	COG1580	Controls the rotational direction of flagella during chemotaxis
HB764_15000	COG0705	Rhomboid family
HB764_15015	COG2177	Part of the ABC transporter FtsEX involved in
HB764_15020	COG2884	Cell division ATP-binding protein ftsE
HB764_15025	COG0552	protein localization to endoplasmic reticulum
HB764_15030	COG0742	ribosomal rna small subunit methyltransferase
HB764_15040	COG2095	MarC family integral membrane protein
HB764_15085	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HB764_15090	COG0640	Transcriptional regulator
HB764_15095	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HB764_15100	COG1280	lysine exporter protein (LysE YggA)
HB764_15105	COG2267	carboxylic ester hydrolase activity
HB764_15110	COG0561	phosphatase activity
HB764_15125	COG3148	PFAM DTW domain containing protein
HB764_15130	COG2200	EAL domain
HB764_15130	COG3287	FIST C domain
HB764_15130	COG2199	diguanylate cyclase activity
HB764_15135	COG1011	Hydrolase
HB764_15155	COG0019	diaminopimelate decarboxylase activity
HB764_15180	COG1587	Uroporphyrinogen-III synthase
HB764_15185	COG2959	enzyme of heme biosynthesis
HB764_15190	COG3071	HemY protein
HB764_15230	COG0633	Ferredoxin
HB764_15235	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HB764_15250	COG3118	belongs to the thioredoxin family
HB764_15265	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HB764_15275	COG0514	ATP-dependent DNA helicase (RecQ)
HB764_15280	COG2962	Rard protein
HB764_15290	COG1280	lysine exporter protein (LysE YggA)
HB764_15295	COG0405	Gamma-glutamyltransferase
HB764_15300	COG0210	DNA helicase
HB764_15310	COG3220	belongs to the UPF0276 family
HB764_15330	COG2814	Major facilitator Superfamily
HB764_15340	COG0006	proline dipeptidase activity
HB764_15340	COG0006	proline dipeptidase activity
HB764_15355	COG2104	thiamine diphosphate biosynthetic process
HB764_15360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HB764_15380	COG2132	Multicopper oxidase
HB764_15425	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HB764_15450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HB764_15455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HB764_15460	COG0551	DNA topoisomerase type I activity
HB764_15470	COG0758	DNA mediated transformation
HB764_15480	COG0242	peptide deformylase activity
HB764_15490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HB764_15490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HB764_15495	COG0569	domain protein
HB764_15500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HB764_15510	COG1272	protein, Hemolysin III
HB764_15515	COG4326	sporulation control protein
HB764_15525	COG3084	Protein conserved in bacteria
HB764_15535	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HB764_15540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB764_15545	COG0204	Acyl-transferase
HB764_15555	COG2199	diguanylate cyclase activity
HB764_15560	COG0606	chelatase, subunit chli
HB764_15570	COG3978	acetolactate synthase activity
HB764_15575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HB764_15580	COG0129	dihydroxy-acid dehydratase activity
HB764_15590	COG0583	DNA-binding transcription factor activity
HB764_15595	COG2814	Major facilitator Superfamily
HB764_15600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB764_15615	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HB764_15670	COG4128	Pfam Zonular occludens toxin
HB764_15720	COG0023	Translation Initiation Factor
HB764_15740	COG0045	succinate-CoA ligase (ADP-forming) activity
HB764_15740	COG1042	CoA-binding domain protein
HB764_15740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB764_15745	COG0583	DNA-binding transcription factor activity
HB764_15755	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HB764_15760	COG3447	MASE1 domain protein
HB764_15760	COG5002	protein histidine kinase activity
HB764_15760	COG5001	Diguanylate cyclase
HB764_15770	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HB764_15775	COG1984	allophanate hydrolase subunit 2
HB764_15785	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HB764_15790	COG4181	ATPase activity
HB764_15800	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HB764_15805	COG3300	MHYT domain
HB764_15805	COG5001	Diguanylate cyclase
HB764_15815	COG0484	heat shock protein binding
HB764_15850	COG2050	protein possibly involved in aromatic compounds catabolism
HB764_15855	COG0501	Belongs to the peptidase M48B family
HB764_15865	COG2067	long-chain fatty acid transport protein
HB764_15870	COG2267	carboxylic ester hydrolase activity
HB764_15910	COG0307	riboflavin synthase, alpha
HB764_15915	COG0076	glutamate decarboxylase activity
HB764_15920	COG1410	methionine synthase
HB764_15920	COG0646	methionine synthase
HB764_15935	COG0737	Belongs to the 5'-nucleotidase family
HB764_15940	COG3593	DNA synthesis involved in DNA repair
HB764_15950	COG3385	transposase activity
HB764_15955	COG0583	DNA-binding transcription factor activity
HB764_15960	COG2116	formate transmembrane transporter activity
HB764_15970	COG3038	cytochrome b561
HB764_15985	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HB764_15990	COG0513	Belongs to the DEAD box helicase family
HB764_15995	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HB764_16000	COG0840	transmembrane signaling receptor activity
HB764_16005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB764_16025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB764_16035	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HB764_16045	COG2207	Transcriptional regulator
HB764_16050	COG1979	alcohol dehydrogenase
HB764_16060	COG1126	abc transporter atp-binding protein
HB764_16065	COG0765	amino acid transport
HB764_16070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB764_16075	COG0765	amino acid transport
HB764_16080	COG2199	diguanylate cyclase activity
HB764_16080	COG2200	EAL domain
HB764_16080	COG2203	Gaf domain
HB764_16095	COG1609	Transcriptional regulator
HB764_16100	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB764_16100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB764_16105	COG1105	Belongs to the carbohydrate kinase PfkB family
HB764_16110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB764_16110	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HB764_16110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB764_16135	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HB764_16145	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HB764_16170	COG1720	tRNA m6t6A37 methyltransferase activity
HB764_16175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB764_16180	COG1028	Short-chain dehydrogenase reductase Sdr
HB764_16225	COG3433	isochorismatase activity
HB764_16225	COG1535	isochorismatase
HB764_16230	COG4592	Periplasmic binding protein
HB764_16240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB764_16245	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB764_16250	COG1120	ATPase activity
HB764_16265	COG2382	esterase
HB764_16270	COG1629	transport
HB764_16270	COG4774	siderophore transport
HB764_16335	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HB764_16395	COG3005	denitrification pathway
HB764_16445	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HB764_16450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB764_16455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB764_16460	COG1120	ATPase activity
HB764_16495	COG0583	DNA-binding transcription factor activity
HB764_16515	COG5640	endopeptidase activity
HB764_16520	COG1132	(ABC) transporter
HB764_16560	COG1280	lysine exporter protein (LysE YggA)
HB764_16565	COG2814	Major facilitator Superfamily
HB764_16680	COG0739	heme binding
HB764_16730	COG2146	nitrite reductase [NAD(P)H] activity
HB764_16730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HB764_16735	COG1116	anion transmembrane transporter activity
HB764_16740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB764_16745	COG1116	anion transmembrane transporter activity
HB764_16745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB764_16765	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HB764_16765	COG1648	precorrin-2 dehydrogenase activity
HB764_16770	COG0243	molybdopterin cofactor binding
HB764_16780	COG0814	amino acid
HB764_16820	COG1785	Belongs to the alkaline phosphatase family
HB764_16845	COG0443	Heat shock 70 kDa protein
HB764_16890	COG2200	EAL domain
HB764_16895	COG5002	protein histidine kinase activity
HB764_16930	COG4160	amino acid transport
HB764_16935	COG4215	(ABC) transporter
HB764_16940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB764_16945	COG1126	abc transporter atp-binding protein
HB764_16980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB764_16990	COG1012	belongs to the aldehyde dehydrogenase family
HB764_17005	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB764_17005	COG1902	pentaerythritol trinitrate reductase activity
HB764_17015	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HB764_17020	COG1845	cytochrome c oxidase, subunit III
HB764_17025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HB764_17030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HB764_17035	COG1028	Short-chain dehydrogenase reductase Sdr
HB764_17045	COG1024	Enoyl-CoA hydratase
HB764_17050	COG1024	Enoyl-CoA hydratase
HB764_17065	COG0183	Belongs to the thiolase family
HB764_17075	COG1960	acyl-CoA dehydrogenase activity
HB764_17080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HB764_17085	COG1024	Enoyl-CoA hydratase
HB764_17125	COG3278	Belongs to the heme-copper respiratory oxidase family
HB764_17140	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HB764_17145	COG3300	MHYT domain
HB764_17145	COG5001	Diguanylate cyclase
HB764_17150	COG0513	Belongs to the DEAD box helicase family
HB764_17155	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
HB764_17170	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HB764_17185	COG1119	ATPase activity
HB764_17190	COG2200	EAL domain
HB764_17210	COG0513	Belongs to the DEAD box helicase family
HB764_17215	COG5002	protein histidine kinase activity
HB764_17215	COG5001	Diguanylate cyclase
HB764_17215	COG3447	MASE1 domain protein
HB764_17220	COG0523	cobalamin synthesis protein
HB764_17250	COG0454	-acetyltransferase
HB764_17260	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HB764_17265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HB764_17270	COG1845	cytochrome c oxidase, subunit III
HB764_17275	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HB764_17300	COG3530	Putative quorum-sensing-regulated virulence factor
HB764_17325	COG3186	Phenylalanine-4-hydroxylase
HB764_17330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HB764_17335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB764_17360	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HB764_17365	COG1454	alcohol dehydrogenase
HB764_17370	COG2133	pyrroloquinoline quinone binding
HB764_17375	COG1619	proteins homologs of microcin C7 resistance protein MccF
HB764_17385	COG0783	Belongs to the Dps family
HB764_17400	COG1136	(ABC) transporter
HB764_17420	COG2199	diguanylate cyclase activity
HB764_17430	COG3036	rescue of stalled ribosome
HB764_17435	COG1278	Cold shock
HB764_17465	COG0545	Peptidyl-prolyl cis-trans isomerase
HB764_17470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB764_17480	COG0840	transmembrane signaling receptor activity
HB764_17490	COG2195	Cleaves the N-terminal amino acid of tripeptides
HB764_17505	COG2197	response regulator
HB764_17510	COG3850	Histidine kinase
HB764_17515	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB764_17535	COG3005	denitrification pathway
HB764_17555	COG0183	Belongs to the thiolase family
HB764_17565	COG1280	lysine exporter protein (LysE YggA)
HB764_17575	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB764_17580	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB764_17660	COG0673	inositol 2-dehydrogenase activity
HB764_17685	COG0583	DNA-binding transcription factor activity
HB764_17695	COG1522	sequence-specific DNA binding
HB764_17700	COG0531	amino acid
HB764_17705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB764_17715	COG2205	protein histidine kinase activity
HB764_17720	COG0745	RESPONSE REGULATOR receiver
HB764_17745	COG1566	PFAM secretion protein HlyD family protein
HB764_17750	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HB764_17755	COG2239	Acts as a magnesium transporter
HB764_17760	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HB764_17765	COG0402	S-adenosylhomocysteine deaminase activity
HB764_17780	COG1418	mRNA catabolic process
HB764_17795	COG2814	Major facilitator Superfamily
HB764_17805	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HB764_17825	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB764_17840	COG4221	oxidoreductase activity
HB764_17845	COG0745	RESPONSE REGULATOR receiver
HB764_17850	COG2205	protein histidine kinase activity
HB764_17860	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HB764_17865	COG2194	sulfuric ester hydrolase activity
HB764_17875	COG0673	inositol 2-dehydrogenase activity
HB764_17880	COG4977	sequence-specific DNA binding
HB764_17890	COG2814	Major facilitator Superfamily
HB764_17915	COG0583	DNA-binding transcription factor activity
HB764_17950	COG0366	Alpha amylase catalytic
HB764_17955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB764_17960	COG0784	Response regulator, receiver
HB764_17960	COG0835	chemotaxis
HB764_17970	COG0748	coenzyme F420 binding
HB764_17975	COG3721	Heme iron utilization protein
HB764_17985	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HB764_17990	COG0811	peptide transport
HB764_17995	COG0848	biopolymer transport protein
HB764_18005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB764_18010	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HB764_18050	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HB764_18060	COG0633	Ferredoxin
HB764_18060	COG3217	Mosc domain protein beta barrel domain protein
HB764_18060	COG0633	Ferredoxin
HB764_18060	COG3217	Mosc domain protein beta barrel domain protein
HB764_18075	COG2354	Protein conserved in bacteria
HB764_18105	COG3833	ABC-type maltose transport systems, permease component
HB764_18110	COG1175	transmembrane transport
HB764_18120	COG3842	ATPase activity
HB764_18125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HB764_18140	COG0489	protein tyrosine kinase activity
HB764_18140	COG3206	protein involved in exopolysaccharide biosynthesis
HB764_18185	COG1309	transcriptional regulator
HB764_18190	COG2130	NADP-dependent
HB764_18200	COG0753	catalase activity
HB764_18205	COG2084	Dehydrogenase
HB764_18240	COG1301	dicarboxylic acid transport
HB764_18245	COG1252	NADH dehydrogenase
HB764_18265	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
HB764_18285	COG3852	Histidine kinase
HB764_18290	COG2204	response regulator
HB764_18315	COG2197	response regulator
HB764_18335	COG0714	Associated with various cellular activities
HB764_18355	COG2304	oxidoreductase activity
HB764_18370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HB764_18375	COG0581	inorganic phosphate transmembrane transporter activity
HB764_18380	COG0573	inorganic phosphate transmembrane transporter activity
HB764_18390	COG0840	transmembrane signaling receptor activity
HB764_18410	COG4771	TonB-dependent receptor
HB764_18415	COG1770	oligopeptidase
HB764_18425	COG0513	Belongs to the DEAD box helicase family
HB764_18435	COG1376	ErfK ybiS ycfS ynhG family protein
HB764_18435	COG1388	LysM domain
HB764_18440	COG0415	Belongs to the DNA photolyase family
HB764_18445	COG0789	Transcriptional regulator
HB764_18450	COG3272	Protein of unknown function (DUF1722)
HB764_18455	COG0813	purine-nucleoside phosphorylase activity
HB764_18485	COG1566	PFAM secretion protein HlyD family protein
HB764_18495	COG1122	ATPase activity
HB764_18515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB764_18535	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HB764_18545	COG1067	ATP-dependent peptidase activity
HB764_18555	COG4172	Belongs to the ABC transporter superfamily
HB764_18560	COG1505	serine-type exopeptidase activity
HB764_18565	COG0583	DNA-binding transcription factor activity
HB764_18570	COG1620	l-lactate permease
HB764_18580	COG1304	FMN binding
HB764_18590	COG0668	transmembrane transport
HB764_18600	COG1063	alcohol dehydrogenase
HB764_18605	COG2223	nitrite transmembrane transporter activity
HB764_18610	COG2199	diguanylate cyclase activity
HB764_18610	COG2203	Gaf domain
HB764_18635	COG1063	alcohol dehydrogenase
HB764_18655	COG4695	Portal protein
HB764_18755	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HB764_18755	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HB764_18775	COG1028	Short-chain dehydrogenase reductase Sdr
HB764_18800	COG3746	phosphate-selective porin O and P
HB764_18820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB764_18860	COG0513	Belongs to the DEAD box helicase family
HB764_18870	COG0583	DNA-binding transcription factor activity
HB764_18890	COG1902	pentaerythritol trinitrate reductase activity
HB764_18895	COG3853	Toxic anion resistance protein (TelA)
HB764_18905	COG2255	four-way junction helicase activity
HB764_18920	COG3122	Protein conserved in bacteria
HB764_18925	COG2321	neutral zinc metallopeptidase
HB764_18935	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HB764_18940	COG1215	transferase activity, transferring glycosyl groups
HB764_18950	COG0583	DNA-binding transcription factor activity
HB764_18955	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HB764_18965	COG2207	Transcriptional regulator
HB764_18970	COG2807	transmembrane transport
HB764_18980	COG0574	Belongs to the PEP-utilizing enzyme family
HB764_18980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HB764_19005	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HB764_19015	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HB764_19050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB764_19080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB764_19130	COG4948	Mandelate Racemase Muconate Lactonizing
HB764_19170	COG4176	ABC-type proline glycine betaine transport system permease component
HB764_19175	COG3448	diguanylate cyclase activity
HB764_19175	COG4175	Glycine betaine
HB764_19190	COG0583	DNA-binding transcription factor activity
HB764_19200	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HB764_19230	COG1335	isochorismatase
HB764_19245	COG1349	DNA-binding transcription factor activity
HB764_19250	COG0346	lactoylglutathione lyase activity
HB764_19255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB764_19255	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB764_19265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB764_19285	COG1280	lysine exporter protein (LysE YggA)
HB764_19290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HB764_19305	COG0488	(ABC) transporter
HB764_19310	COG0435	Glutathione S-transferase
HB764_19315	COG0431	NADPH-dependent FMN reductase
HB764_19320	COG0583	DNA-binding transcription factor activity
HB764_19325	COG4628	conserved protein (DUF2132)
HB764_19330	COG0488	(ABC) transporter
HB764_19345	COG0346	lactoylglutathione lyase activity
HB764_19350	COG0384	phenazine biosynthesis protein PhzF
HB764_19380	COG2205	protein histidine kinase activity
HB764_19385	COG0745	RESPONSE REGULATOR receiver
HB764_19395	COG0454	-acetyltransferase
HB764_19405	COG2814	Major facilitator Superfamily
HB764_19415	COG2988	succinylglutamate desuccinylase activity
HB764_19425	COG0628	permease
HB764_19430	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HB764_19445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB764_19455	COG4628	conserved protein (DUF2132)
HB764_19460	COG0583	DNA-binding transcription factor activity
HB764_19470	COG1686	Belongs to the peptidase S11 family
HB764_19495	COG0415	Belongs to the DNA photolyase family
HB764_19500	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HB764_19510	COG4667	esterase of the alpha-beta hydrolase superfamily
HB764_19525	COG1596	polysaccharide export
HB764_19535	COG3206	protein involved in exopolysaccharide biosynthesis
HB764_19535	COG0489	protein tyrosine kinase activity
HB764_19555	COG1301	dicarboxylic acid transport
HB764_19560	COG3339	Conserved Protein
HB764_19575	COG2207	Transcriptional regulator
HB764_19590	COG0366	Alpha amylase catalytic
HB764_19595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HB764_19600	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HB764_19605	COG1640	4-alpha-glucanotransferase
HB764_19610	COG0058	SHG alpha-glucan phosphorylase activity
HB764_19630	COG1999	signal sequence binding
HB764_19640	COG1263	PTS System
HB764_19640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB764_19645	COG1162	GTPase activity
HB764_19650	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HB764_19680	COG2356	endonuclease I
HB764_19750	COG0697	spore germination
HB764_19755	COG0583	DNA-binding transcription factor activity
HB764_19765	COG4580	involved in the transport of maltose and maltodextrins
HB764_19785	COG2814	Major facilitator Superfamily
HB764_19800	COG0739	heme binding
HB764_19835	COG3121	Chaperone
HB764_19865	COG0612	Peptidase, M16
HB764_19870	COG0840	transmembrane signaling receptor activity
HB764_19890	COG1335	isochorismatase
HB764_19895	COG1136	(ABC) transporter
HB764_19900	COG0577	efflux transmembrane transporter activity
HB764_19950	COG1764	response to oxidative stress
HB764_19955	COG1846	Transcriptional regulator
HB764_19965	COG3634	alkyl hydroperoxide reductase activity
HB764_19975	COG2610	gluconate transmembrane transporter activity
HB764_19980	COG3622	Belongs to the hyi family
HB764_19985	COG0235	Class ii aldolase
HB764_19990	COG3395	kinase activity
HB764_19995	COG2084	Dehydrogenase
HB764_20000	COG1349	DNA-binding transcription factor activity
HB764_20040	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HB764_20050	COG3766	membrane
HB764_20060	COG0754	glutathionylspermidine amidase activity
HB764_20065	COG3831	ATPase activity
HB764_20070	COG0714	Associated with various cellular activities
HB764_20075	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HB764_20080	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HB764_20105	COG1522	sequence-specific DNA binding
HB764_20110	COG0544	peptidyl-prolyl cis-trans isomerase activity
HB764_20115	COG0544	peptidyl-prolyl cis-trans isomerase activity
HB764_20130	COG2258	MOSC domain
HB764_20135	COG2153	protein acetylation
HB764_20145	COG3713	MltA-interacting MipA family protein
HB764_20150	COG0513	Belongs to the DEAD box helicase family
HB764_20155	COG0667	Aldo Keto reductase
HB764_20175	COG1132	(ABC) transporter
HB764_20290	COG4166	transmembrane transport
HB764_20305	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HB764_20310	COG1263	PTS System
HB764_20310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB764_20315	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HB764_20340	COG1444	tRNA N-acetyltransferase activity
HB764_20365	COG4608	Belongs to the ABC transporter superfamily
HB764_20370	COG0444	Belongs to the ABC transporter superfamily
HB764_20380	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
HB764_20380	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HB764_20415	COG1136	(ABC) transporter
HB764_20435	COG3275	phosphorelay sensor kinase activity
HB764_20440	COG3279	Response regulator of the LytR AlgR family
HB764_20450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HB764_20470	COG0786	glutamate:sodium symporter activity
HB764_20475	COG1028	Short-chain dehydrogenase reductase Sdr
HB764_20525	COG0583	DNA-binding transcription factor activity
HB764_20540	COG2897	thiosulfate sulfurtransferase activity
HB764_20550	COG1131	(ABC) transporter
HB764_20555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB764_20580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB764_20590	COG0561	phosphatase activity
HB764_20595	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HB764_20600	COG3623	hexulose-6-phosphate isomerase
HB764_20635	COG2259	Doxx family
HB764_20645	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HB764_20650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HB764_20740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HB764_20785	COG1609	Transcriptional regulator
HB764_20800	COG0395	ABC-type sugar transport system, permease component
HB764_20805	COG2723	6-phospho-beta-galactosidase activity
HB764_20810	COG3842	ATPase activity
HB764_20815	COG1609	Transcriptional regulator
HB764_20825	COG0564	pseudouridine synthase activity
HB764_20830	COG0561	phosphatase activity
HB764_20850	COG3152	Membrane
HB764_20865	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HB764_20880	COG0583	DNA-binding transcription factor activity
HB764_20930	COG2076	Multidrug Resistance protein
HB764_20940	COG1357	PFAM Pentapeptide repeats (8 copies)
HB764_20945	COG3047	cAMP biosynthetic process
HB764_21040	COG0668	transmembrane transport
HB764_21085	COG3835	regulator
HB764_21090	COG1929	Belongs to the glycerate kinase type-1 family
HB764_21115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB764_21145	COG0456	acetyltransferase
HB764_21165	COG1028	Short-chain dehydrogenase reductase Sdr
HB764_21185	COG0671	phosphoesterase, PA-phosphatase related
HB764_21200	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HB764_21205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB764_21210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB764_21215	COG1116	anion transmembrane transporter activity
HB764_21220	COG0351	phosphomethylpyrimidine kinase
HB764_21225	COG0312	modulator of DNA gyrase
HB764_21230	COG0312	modulator of DNA gyrase
HB764_21290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HB764_21300	COG0584	glycerophosphoryl diester phosphodiesterase
HB764_21305	COG0745	RESPONSE REGULATOR receiver
HB764_21325	COG0811	peptide transport
HB764_21330	COG0811	peptide transport
HB764_21335	COG0848	biopolymer transport protein
HB764_21380	COG0803	Belongs to the bacterial solute-binding protein 9 family
HB764_21385	COG1121	(ABC) transporter
HB764_21390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB764_21405	COG1770	oligopeptidase
HB764_21410	COG2814	Major facilitator Superfamily
HB764_21415	COG0010	Belongs to the arginase family
HB764_21420	COG1166	arginine decarboxylase activity
HB764_21430	COG0189	ligase activity
HB764_21430	COG4067	protein conserved in archaea
HB764_21435	COG0189	ligase activity
HB764_21455	COG0583	DNA-binding transcription factor activity
HB764_21480	COG2723	6-phospho-beta-galactosidase activity
HB764_21495	COG1114	Component of the transport system for branched-chain amino acids
HB764_21510	COG0579	oxidoreductase
HB764_21515	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HB764_21530	COG3033	Beta-eliminating lyase
HB764_21545	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB764_21550	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HB764_21585	COG3706	GGDEF domain
HB764_21590	COG0415	Belongs to the DNA photolyase family
HB764_21595	COG3046	protein related to deoxyribodipyrimidine photolyase
HB764_21610	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB764_21610	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB764_21615	COG1765	OsmC-like protein
HB764_21665	COG1011	Hydrolase
HB764_21690	COG3240	lipase activity
HB764_21710	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HB764_21720	COG1840	ABC-type Fe3 transport system, periplasmic component
HB764_21725	COG3842	ATPase activity
HB764_21750	COG2990	Protein conserved in bacteria
HB764_21775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB764_21780	COG2866	Carboxypeptidase
HB764_21790	COG0583	DNA-binding transcription factor activity
HB764_21815	COG3104	oligopeptide transport
HB764_21820	COG1760	l-serine dehydratase
HB764_21845	COG0741	lytic transglycosylase activity
HB764_21845	COG1388	LysM domain
HB764_21865	COG1815	bacterial-type flagellum-dependent cell motility
HB764_21870	COG1558	bacterial-type flagellum-dependent cell motility
HB764_21875	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HB764_21880	COG1749	Flagellar hook protein flgE
HB764_21885	COG4787	bacterial-type flagellum-dependent cell motility
HB764_21890	COG4786	Flagellar basal body rod
HB764_21895	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HB764_21900	COG1706	bacterial-type flagellum-dependent cell motility
HB764_21910	COG1256	bacterial-type flagellum assembly
HB764_21910	COG4786	Flagellar basal body rod
HB764_21915	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB764_21980	COG0384	phenazine biosynthesis protein PhzF
HB764_21990	COG1360	Flagellar Motor Protein
HB764_21995	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HB764_22000	COG1191	sigma factor activity
HB764_22005	COG1580	Controls the rotational direction of flagella during chemotaxis
HB764_22025	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HB764_22035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB764_22050	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HB764_22060	COG1987	bacterial-type flagellum assembly
HB764_22160	COG0346	lactoylglutathione lyase activity
HB764_22180	COG0745	RESPONSE REGULATOR receiver
HB764_22205	COG0156	8-amino-7-oxononanoate synthase activity
HB764_22210	COG1063	alcohol dehydrogenase
HB764_22215	COG4974	Belongs to the 'phage' integrase family
HB764_22250	COG0456	acetyltransferase
HB764_22285	COG0583	DNA-binding transcription factor activity
HB764_22315	COG3483	tryptophan 2,3-dioxygenase activity
HB764_22320	COG1028	Short-chain dehydrogenase reductase Sdr
HB764_22335	COG0823	Involved in the tonB-independent uptake of proteins
HB764_22340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB764_22345	COG2084	Dehydrogenase
HB764_22350	COG1764	response to oxidative stress
HB764_22415	COG0625	glutathione transferase activity
HB764_22420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB764_22425	COG1686	Belongs to the peptidase S11 family
HB764_22435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB764_22445	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HB764_22460	COG1278	Cold shock
HB764_22465	COG1741	Belongs to the pirin family
HB764_22470	COG4667	esterase of the alpha-beta hydrolase superfamily
HB764_22480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HB764_22490	COG0523	cobalamin synthesis protein
HB764_22515	COG3842	ATPase activity
HB764_22520	COG0395	ABC-type sugar transport system, permease component
HB764_22525	COG1175	transmembrane transport
HB764_22535	COG0584	glycerophosphoryl diester phosphodiesterase
HB764_22545	COG0589	response to stress
HB764_22555	COG0488	(ABC) transporter
HB764_22560	COG1505	serine-type exopeptidase activity
HB764_22590	COG1858	cytochrome C peroxidase
HB764_22605	COG0494	nUDIX hydrolase
HB764_22620	COG0583	DNA-binding transcription factor activity
HB764_22625	COG1280	lysine exporter protein (LysE YggA)
HB764_22635	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB764_22670	COG0842	Transport permease protein
HB764_22675	COG1131	(ABC) transporter
HB764_22695	COG0800	Aldolase
HB764_22705	COG2706	6-phosphogluconolactonase activity
HB764_22710	COG0251	oxidation-reduction process
HB764_22725	COG0798	PFAM Bile acid sodium symporter
HB764_22750	COG1120	ATPase activity
HB764_22755	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HB764_22790	COG0814	amino acid
HB764_22805	COG3314	Sporulation integral membrane protein YlbJ
HB764_22825	COG0739	heme binding
HB764_22830	COG5001	Diguanylate cyclase
HB764_22835	COG1120	ATPase activity
HB764_22865	COG0583	DNA-binding transcription factor activity
HB764_22870	COG2814	Major facilitator Superfamily
HB764_22885	COG0697	spore germination
HB764_22900	COG0179	Fumarylacetoacetate (FAA) hydrolase
HB764_22920	COG1280	lysine exporter protein (LysE YggA)
HB764_22930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HB764_22945	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HB764_22970	COG1612	heme a metabolic process
HB764_22985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB764_22995	COG0840	transmembrane signaling receptor activity
HB764_23000	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HB764_23020	COG2897	thiosulfate sulfurtransferase activity
HB764_23055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HB764_23060	COG0303	'Molybdopterin
HB764_23090	COG4989	oxidoreductase activity
HB764_23105	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HB764_23105	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HB764_23140	COG0583	DNA-binding transcription factor activity
HB764_23160	COG4964	Belongs to the GSP D family
HB764_23170	COG0455	bacterial-type flagellum organization
HB764_23210	COG2885	chlorophyll binding
HB764_23245	COG4176	ABC-type proline glycine betaine transport system permease component
HB764_23250	COG0517	IMP dehydrogenase activity
HB764_23250	COG4175	Glycine betaine
HB764_23265	COG0330	HflC and HflK could
HB764_23315	COG0586	Pfam SNARE associated Golgi protein
HB764_23340	COG5001	Diguanylate cyclase
HB764_23350	COG1129	ABC transporter
HB764_23355	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB764_23360	COG1879	ABC-type sugar transport system periplasmic component
HB764_23365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB764_23370	COG1609	Transcriptional regulator
HB764_23385	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HB764_23400	COG4607	ABC-type enterochelin transport system periplasmic component
HB764_23405	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB764_23410	COG4605	iron ion homeostasis
HB764_23415	COG4604	ABC transporter, ATP-binding protein
HB764_23420	COG0789	Transcriptional regulator
HB764_23445	COG1289	transmembrane transporter activity
HB764_23450	COG0210	DNA helicase
HB764_23460	COG1879	ABC-type sugar transport system periplasmic component
HB764_23465	COG2198	Histidine kinase
HB764_23465	COG0784	Response regulator, receiver
HB764_23465	COG2205	protein histidine kinase activity
HB764_23655	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HB764_23665	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HB764_23695	COG3069	C4-dicarboxylate transmembrane transporter activity
HB764_23725	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HB764_23760	COG2003	Belongs to the UPF0758 family
HB764_23765	COG0328	RNA-DNA hybrid ribonuclease activity
HB764_23795	COG0494	nUDIX hydrolase
HB764_23815	COG1715	Restriction endonuclease
HB764_23820	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
HB764_23840	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HB764_23855	COG0582	viral genome integration into host DNA
HB764_23860	COG0739	heme binding
HB764_23945	COG2204	response regulator
HB764_23985	COG0515	serine threonine protein kinase
HB764_24020	COG1522	sequence-specific DNA binding
HB764_24235	COG0778	Nitroreductase
HB764_24240	COG0835	chemotaxis
HB764_24240	COG0784	Response regulator, receiver
HB764_24250	COG2962	Rard protein
HB764_24300	COG5642	Protein of unknown function (DUF2384)
HB764_24310	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HB764_24310	COG2755	lipolytic protein G-D-S-L family
HB764_24335	COG0840	transmembrane signaling receptor activity
HB764_24350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HB764_24380	COG0420	3'-5' exonuclease activity
HB764_24385	COG0419	ATPase involved in DNA repair
HB764_24395	COG3469	chitinase activity
HB764_24425	COG3040	lipid binding
HB764_24435	COG1288	antiporter activity
HB764_24445	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HB764_24460	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HB764_24475	COG0583	DNA-binding transcription factor activity
HB764_24480	COG0277	FAD linked oxidase domain protein
HB764_24555	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HB764_24560	COG0840	transmembrane signaling receptor activity
HB764_24585	COG3118	belongs to the thioredoxin family
HB764_24590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HB764_24645	COG1328	CTP reductase activity
HB764_24650	COG0602	queuosine metabolic process
HB764_24680	COG3111	PFAM Bacterial OB fold (BOF) protein
HB764_24690	COG0725	ABC transporter, periplasmic molybdate-binding protein
HB764_24695	COG4149	molybdate abc transporter
HB764_24700	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HB764_24710	COG2203	Gaf domain
HB764_24710	COG3706	GGDEF domain
HB764_24710	COG4251	negative regulation of phosphorylation
HB764_24710	COG5001	Diguanylate cyclase
HB764_24730	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HB764_24735	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HB764_24760	COG3140	Belongs to the UPF0181 family
HB764_24855	COG4128	Pfam Zonular occludens toxin
HB764_24905	COG0023	Translation Initiation Factor
HB764_24990	COG0629	single-stranded DNA binding
HB764_25520	COG1192	Involved in chromosome partitioning
HB764_25660	COG0616	signal peptide processing
HB764_25840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HB764_25980	COG0616	signal peptide processing
HB764_26110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HB764_26115	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HB764_26120	COG1192	Involved in chromosome partitioning
HB764_26145	COG1683	Conserved Protein
HB764_26190	COG2801	Transposase and inactivated derivatives
HB764_26290	COG1917	Cupin 2, conserved barrel domain protein
HB764_26290	COG2207	Transcriptional regulator
HB764_26295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB764_26305	COG4821	SIS domain
HB764_26350	COG0778	Nitroreductase
HB764_26525	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HB764_26540	COG1192	Involved in chromosome partitioning