locus-tag	class	description
HB763_00015	COG0123	including yeast histone deacetylase and acetoin utilization protein
HB763_00030	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HB763_00035	COG0778	Nitroreductase
HB763_00040	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB763_00040	COG1902	pentaerythritol trinitrate reductase activity
HB763_00045	COG0616	signal peptide processing
HB763_00050	COG0252	asparaginase activity
HB763_00055	COG3139	Protein of unknown function (DUF1315)
HB763_00065	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB763_00070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HB763_00090	COG2226	methyltransferase
HB763_00110	COG1785	Belongs to the alkaline phosphatase family
HB763_00130	COG0668	transmembrane transport
HB763_00135	COG0076	glutamate decarboxylase activity
HB763_00140	COG2985	domain, Protein
HB763_00145	COG2261	transglycosylase associated protein
HB763_00150	COG2983	Belongs to the UPF0260 family
HB763_00160	COG2964	Protein conserved in bacteria
HB763_00170	COG0251	oxidation-reduction process
HB763_00175	COG0814	amino acid
HB763_00180	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HB763_00205	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HB763_00215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HB763_00225	COG2832	Protein of unknown function (DUF454)
HB763_00230	COG0745	RESPONSE REGULATOR receiver
HB763_00235	COG0583	DNA-binding transcription factor activity
HB763_00240	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HB763_00245	COG1286	toxin biosynthetic process
HB763_00250	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HB763_00255	COG0285	dihydrofolate synthase activity
HB763_00275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HB763_00280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HB763_00285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HB763_00305	COG3101	peptidyl-lysine hydroxylation
HB763_00310	COG2860	membrane
HB763_00325	COG2890	protein-(glutamine-N5) methyltransferase activity
HB763_00335	COG2062	phosphohistidine phosphatase, SixA
HB763_00350	COG0183	Belongs to the thiolase family
HB763_00365	COG2067	long-chain fatty acid transport protein
HB763_00370	COG2067	long-chain fatty acid transport protein
HB763_00375	COG2853	Lipoprotein
HB763_00380	COG4235	cytochrome complex assembly
HB763_00380	COG3088	subunit of a heme lyase
HB763_00390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HB763_00395	COG1138	Cytochrome C-type biogenesis protein
HB763_00410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HB763_00415	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HB763_00420	COG4133	protoheme IX ABC transporter activity
HB763_00430	COG0835	chemotaxis
HB763_00440	COG1192	Involved in chromosome partitioning
HB763_00445	COG2201	protein-glutamate methylesterase activity
HB763_00450	COG0784	Response regulator, receiver
HB763_00450	COG2198	Histidine kinase
HB763_00450	COG0643	Histidine kinase
HB763_00455	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HB763_00490	COG1684	flagellar biosynthetic protein fliR
HB763_00495	COG1987	bacterial-type flagellum assembly
HB763_00550	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HB763_00560	COG1677	Flagellar hook-basal body complex protein FliE
HB763_00580	COG1516	flagellar protein fliS
HB763_00590	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HB763_00595	COG1334	flagellar protein FlaG
HB763_00600	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB763_00605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB763_00610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB763_00615	COG2837	iron assimilation
HB763_00640	COG1393	Belongs to the ArsC family
HB763_00660	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HB763_00665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HB763_00670	COG2716	regulation of RNA biosynthetic process
HB763_00700	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HB763_00735	COG4584	PFAM Integrase catalytic
HB763_00740	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HB763_00740	COG0515	serine threonine protein kinase
HB763_00745	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HB763_00760	COG3501	Rhs element vgr protein
HB763_00800	COG3335	DDE superfamily endonuclease
HB763_00815	COG3344	reverse transcriptase
HB763_00850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HB763_00865	COG4783	chaperone-mediated protein folding
HB763_00870	COG1393	Belongs to the ArsC family
HB763_00890	COG2233	PERMEase
HB763_00895	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HB763_00900	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HB763_00905	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HB763_00910	COG0121	glutamine amidotransferase
HB763_00915	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HB763_00920	COG1960	acyl-CoA dehydrogenase activity
HB763_00940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HB763_00950	COG2226	methyltransferase
HB763_00960	COG0741	lytic transglycosylase activity
HB763_00960	COG1388	LysM domain
HB763_00975	COG0347	Belongs to the P(II) protein family
HB763_00995	COG0587	DNA-directed DNA polymerase activity
HB763_01020	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HB763_01025	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HB763_01035	COG0750	zinc metalloprotease
HB763_01045	COG0575	Belongs to the CDS family
HB763_01050	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HB763_01075	COG0024	Methionine aminopeptidase
HB763_01090	COG0564	pseudouridine synthase activity
HB763_01095	COG3098	single-species biofilm formation
HB763_01125	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HB763_01140	COG1720	tRNA m6t6A37 methyltransferase activity
HB763_01165	COG0733	neurotransmitter:sodium symporter activity
HB763_01180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB763_01185	COG0514	ATP-dependent DNA helicase (RecQ)
HB763_01190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HB763_01205	COG1477	protein flavinylation
HB763_01215	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HB763_01220	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HB763_01230	COG1805	sodium ion transport
HB763_01235	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HB763_01240	COG0271	Belongs to the BolA IbaG family
HB763_01270	COG1595	DNA-templated transcription, initiation
HB763_01285	COG3248	Nucleoside-binding outer membrane protein
HB763_01290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HB763_01295	COG0693	protein deglycase activity
HB763_01300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HB763_01305	COG2166	iron-sulfur cluster assembly
HB763_01310	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HB763_01315	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HB763_01325	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HB763_01325	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HB763_01335	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HB763_01340	COG1074	ATP-dependent DNA helicase activity
HB763_01345	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HB763_01370	COG3141	response to X-ray
HB763_01385	COG2171	N-acyltransferase activity
HB763_01390	COG0584	glycerophosphoryl diester phosphodiesterase
HB763_01395	COG2271	Major facilitator Superfamily
HB763_01400	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HB763_01410	COG1349	DNA-binding transcription factor activity
HB763_01415	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HB763_01440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HB763_01445	COG0768	penicillin binding
HB763_01450	COG1609	Transcriptional regulator
HB763_01455	COG0583	DNA-binding transcription factor activity
HB763_01470	COG1022	Amp-dependent synthetase and ligase
HB763_01475	COG3385	transposase activity
HB763_01505	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HB763_01510	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HB763_01520	COG0560	Phosphoserine phosphatase
HB763_01530	COG0813	purine-nucleoside phosphorylase activity
HB763_01540	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HB763_01550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB763_01555	COG0084	hydrolase, TatD family'
HB763_01585	COG3153	acetyltransferase
HB763_01590	COG3154	lipid carrier protein
HB763_01600	COG0826	peptidase U32
HB763_01605	COG0826	peptidase U32
HB763_01610	COG0534	Mate efflux family protein
HB763_01630	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HB763_01650	COG0195	Participates in both transcription termination and antitermination
HB763_01670	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HB763_01685	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HB763_01690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HB763_01700	COG1534	Rna-binding protein
HB763_01705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB763_01710	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HB763_01715	COG2027	D-alanyl-D-alanine carboxypeptidase
HB763_01730	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HB763_01735	COG0739	heme binding
HB763_01740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB763_01760	COG0628	permease
HB763_01770	COG2205	protein histidine kinase activity
HB763_01770	COG2198	Histidine kinase
HB763_01770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB763_01770	COG0784	Response regulator, receiver
HB763_01775	COG0747	negative chemotaxis
HB763_01785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB763_01790	COG0444	Belongs to the ABC transporter superfamily
HB763_01795	COG4608	Belongs to the ABC transporter superfamily
HB763_01805	COG2971	BadF BadG BcrA BcrD
HB763_01820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HB763_01825	COG3842	ATPase activity
HB763_01835	COG1840	ABC-type Fe3 transport system, periplasmic component
HB763_01840	COG0004	ammonium transporteR
HB763_01855	COG1049	propionate catabolic process, 2-methylcitrate cycle
HB763_01860	COG1752	Esterase of the alpha-beta hydrolase superfamily
HB763_01865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HB763_01870	COG1643	Atp-dependent helicase
HB763_01885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HB763_01895	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HB763_01915	COG0842	Transport permease protein
HB763_01920	COG1131	(ABC) transporter
HB763_01925	COG0659	secondary active sulfate transmembrane transporter activity
HB763_01930	COG0288	reversible hydration of carbon dioxide
HB763_01945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB763_01950	COG0508	dehydrogenase complex catalyzes the overall conversion of
HB763_01955	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HB763_01960	COG2186	Transcriptional regulator
HB763_01980	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB763_01985	COG1459	type II secretion system
HB763_01995	COG0237	dephospho-CoA kinase activity
HB763_02000	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HB763_02005	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HB763_02025	COG0228	four-way junction DNA binding
HB763_02030	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HB763_02035	COG4137	Cytochrome C assembly protein
HB763_02040	COG4536	flavin adenine dinucleotide binding
HB763_02060	COG0612	Peptidase, M16
HB763_02065	COG1238	metal cluster binding
HB763_02075	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HB763_02080	COG0511	ligase activity, forming carbon-carbon bonds
HB763_02080	COG5016	pyruvate
HB763_02085	COG3630	sodium ion export across plasma membrane
HB763_02090	COG3335	DDE superfamily endonuclease
HB763_02180	COG0527	aspartate kinase activity
HB763_02195	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HB763_02200	COG1546	Belongs to the CinA family
HB763_02210	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HB763_02240	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HB763_02250	COG0148	phosphopyruvate hydratase activity
HB763_02260	COG3956	TIGRFAM MazG family protein
HB763_02265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HB763_02285	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HB763_02290	COG1381	Involved in DNA repair and RecF pathway recombination
HB763_02295	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HB763_02315	COG3086	response to oxidative stress
HB763_02330	COG1595	DNA-templated transcription, initiation
HB763_02335	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HB763_02345	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HB763_02365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB763_02370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB763_02380	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HB763_02390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HB763_02400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HB763_02425	COG0668	transmembrane transport
HB763_02430	COG0191	fructose-bisphosphate aldolase activity
HB763_02450	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HB763_02470	COG2356	endonuclease I
HB763_02475	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HB763_02480	COG0189	ligase activity
HB763_02485	COG1678	Uncharacterized ACR, COG1678
HB763_02490	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HB763_02505	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HB763_02510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HB763_02515	COG0762	integral membrane protein
HB763_02530	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HB763_02535	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HB763_02635	COG1012	belongs to the aldehyde dehydrogenase family
HB763_02685	COG1609	Transcriptional regulator
HB763_02695	COG1486	melibiose metabolic process
HB763_02700	COG1447	Phosphotransferase system cellobiose-specific component IIA
HB763_02715	COG0726	polysaccharide deacetylase
HB763_02725	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_02735	COG0795	lipopolysaccharide-transporting ATPase activity
HB763_02740	COG0795	lipopolysaccharide-transporting ATPase activity
HB763_02750	COG2927	DNA polymerase III (CHI subunit)
HB763_02755	COG0525	valine-tRNA ligase activity
HB763_02765	COG0456	acetyltransferase
HB763_02805	COG0251	oxidation-reduction process
HB763_02810	COG0204	Acyl-transferase
HB763_02820	COG5007	Belongs to the BolA IbaG family
HB763_02830	COG2854	intermembrane phospholipid transfer
HB763_02835	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HB763_02840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HB763_02845	COG1127	ABC transporter
HB763_02855	COG0517	IMP dehydrogenase activity
HB763_02855	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HB763_02865	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HB763_02870	COG1137	ATPase activity
HB763_02880	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HB763_02885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB763_02895	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB763_02900	COG2239	Acts as a magnesium transporter
HB763_02905	COG0312	modulator of DNA gyrase
HB763_02915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HB763_02920	COG0564	pseudouridine synthase activity
HB763_02935	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HB763_02940	COG0312	modulator of DNA gyrase
HB763_02945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HB763_02950	COG3164	Protein of unknown function
HB763_02960	COG0424	maF-like protein
HB763_02965	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HB763_02970	COG1792	Involved in formation and maintenance of cell shape
HB763_02975	COG1077	Cell shape determining protein MreB Mrl
HB763_03010	COG2165	general secretion pathway protein
HB763_03020	COG1459	type II secretion system
HB763_03025	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB763_03035	COG3267	Type II secretory pathway component ExeA
HB763_03035	COG3409	Peptidoglycan-binding domain 1 protein
HB763_03060	COG2199	diguanylate cyclase activity
HB763_03060	COG2200	EAL domain
HB763_03065	COG0629	single-stranded DNA binding
HB763_03080	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HB763_03090	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HB763_03095	COG0527	aspartate kinase activity
HB763_03100	COG1410	methionine synthase
HB763_03100	COG0646	methionine synthase
HB763_03165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HB763_03185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HB763_03190	COG0735	belongs to the Fur family
HB763_03205	COG0432	Pfam Uncharacterised protein family UPF0047
HB763_03215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HB763_03220	COG0305	Participates in initiation and elongation during chromosome replication
HB763_03240	COG2965	DNA replication, synthesis of RNA primer
HB763_03250	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HB763_03255	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HB763_03300	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HB763_03310	COG0678	peroxiredoxin activity
HB763_03310	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HB763_03315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB763_03325	COG0165	Argininosuccinate lyase
HB763_03325	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HB763_03340	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HB763_03350	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HB763_03360	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HB763_03365	COG0527	aspartate kinase activity
HB763_03365	COG0460	homoserine dehydrogenase
HB763_03370	COG0626	cystathionine gamma-synthase activity
HB763_03380	COG0281	malic enzyme
HB763_03390	COG2906	2 iron, 2 sulfur cluster binding
HB763_03400	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HB763_03415	COG2168	tRNA wobble position uridine thiolation
HB763_03420	COG2923	Belongs to the DsrF TusC family
HB763_03425	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HB763_03430	COG2964	Protein conserved in bacteria
HB763_03435	COG0545	Peptidyl-prolyl cis-trans isomerase
HB763_03450	COG1446	asparaginase
HB763_03455	COG1047	Peptidyl-prolyl cis-trans
HB763_03470	COG2249	NAD(P)H dehydrogenase (quinone) activity
HB763_03475	COG0488	(ABC) transporter
HB763_03485	COG0429	hydrolase of the alpha beta-hydrolase fold
HB763_03495	COG3954	Phosphoribulokinase
HB763_03500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB763_03520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HB763_03525	COG0512	Glutamine amidotransferase of anthranilate synthase
HB763_03545	COG0546	phosphoglycolate phosphatase activity
HB763_03550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB763_03555	COG0557	exoribonuclease II activity
HB763_03565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB763_03565	COG1017	nitric oxide dioxygenase activity
HB763_03570	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HB763_03575	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HB763_03580	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HB763_03585	COG0330	HflC and HflK could
HB763_03590	COG0330	HflC and HflK could
HB763_03595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HB763_03610	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HB763_03615	COG0860	N-Acetylmuramoyl-L-alanine amidase
HB763_03620	COG0802	atpase or kinase
HB763_03625	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HB763_03695	COG1162	GTPase activity
HB763_03705	COG0471	metal ion transport
HB763_03720	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HB763_03725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HB763_03740	COG1045	serine acetyltransferase
HB763_03745	COG4942	peptidase
HB763_03770	COG1053	succinate dehydrogenase
HB763_03775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HB763_03805	COG1509	lysine 2,3-aminomutase activity
HB763_03830	COG0534	Mate efflux family protein
HB763_03840	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HB763_03850	COG0745	RESPONSE REGULATOR receiver
HB763_03855	COG2205	protein histidine kinase activity
HB763_03920	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HB763_03925	COG0732	type I restriction modification DNA specificity domain
HB763_03930	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HB763_03960	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HB763_03965	COG1074	ATP-dependent DNA helicase activity
HB763_03970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HB763_03975	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HB763_03980	COG3030	protein affecting phage T7 exclusion by the F plasmid
HB763_03985	COG1027	Aspartate ammonia-lyase
HB763_03990	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HB763_03995	COG4232	protein-disulfide reductase activity
HB763_04005	COG2095	MarC family integral membrane protein
HB763_04015	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HB763_04035	COG0784	Response regulator, receiver
HB763_04035	COG2198	Histidine kinase
HB763_04035	COG2205	protein histidine kinase activity
HB763_04040	COG2814	Major facilitator Superfamily
HB763_04055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HB763_04060	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HB763_04065	COG0511	ligase activity, forming carbon-carbon bonds
HB763_04070	COG0439	Biotin carboxylase
HB763_04080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HB763_04085	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HB763_04090	COG2199	diguanylate cyclase activity
HB763_04135	COG1982	Orn Lys Arg decarboxylase major
HB763_04140	COG0531	amino acid
HB763_04145	COG3710	Transcriptional regulator
HB763_04150	COG0789	Transcriptional regulator
HB763_04160	COG0151	Belongs to the GarS family
HB763_04175	COG1253	flavin adenine dinucleotide binding
HB763_04180	COG3068	Protein conserved in bacteria
HB763_04190	COG1573	uracil-dna glycosylase
HB763_04200	COG2816	NAD+ diphosphatase activity
HB763_04205	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HB763_04225	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HB763_04240	COG0250	Participates in transcription elongation, termination and antitermination
HB763_04245	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HB763_04285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HB763_04295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HB763_04395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB763_04400	COG0534	Mate efflux family protein
HB763_04415	COG2937	Belongs to the GPAT DAPAT family
HB763_04425	COG3161	chorismate lyase activity
HB763_04430	COG1580	Controls the rotational direction of flagella during chemotaxis
HB763_04435	COG0705	Rhomboid family
HB763_04450	COG2177	Part of the ABC transporter FtsEX involved in
HB763_04455	COG2884	Cell division ATP-binding protein ftsE
HB763_04460	COG0552	protein localization to endoplasmic reticulum
HB763_04465	COG0742	ribosomal rna small subunit methyltransferase
HB763_04475	COG2095	MarC family integral membrane protein
HB763_04520	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HB763_04525	COG0640	Transcriptional regulator
HB763_04530	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HB763_04535	COG1280	lysine exporter protein (LysE YggA)
HB763_04540	COG2267	carboxylic ester hydrolase activity
HB763_04545	COG0561	phosphatase activity
HB763_04560	COG3148	PFAM DTW domain containing protein
HB763_04565	COG3287	FIST C domain
HB763_04565	COG2199	diguanylate cyclase activity
HB763_04565	COG2200	EAL domain
HB763_04570	COG1011	Hydrolase
HB763_04590	COG0019	diaminopimelate decarboxylase activity
HB763_04605	COG3072	Adenylate cyclase
HB763_04615	COG1587	Uroporphyrinogen-III synthase
HB763_04620	COG2959	enzyme of heme biosynthesis
HB763_04625	COG3071	HemY protein
HB763_04665	COG0633	Ferredoxin
HB763_04670	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HB763_04685	COG3118	belongs to the thioredoxin family
HB763_04700	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HB763_04710	COG0514	ATP-dependent DNA helicase (RecQ)
HB763_04715	COG2962	Rard protein
HB763_04725	COG1280	lysine exporter protein (LysE YggA)
HB763_04730	COG0405	Gamma-glutamyltransferase
HB763_04735	COG0210	DNA helicase
HB763_04745	COG3220	belongs to the UPF0276 family
HB763_04765	COG2814	Major facilitator Superfamily
HB763_04775	COG0006	proline dipeptidase activity
HB763_04775	COG0006	proline dipeptidase activity
HB763_04790	COG2104	thiamine diphosphate biosynthetic process
HB763_04795	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HB763_04815	COG2132	Multicopper oxidase
HB763_04865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HB763_04870	COG1739	Uncharacterized protein family UPF0029
HB763_04880	COG0183	Belongs to the thiolase family
HB763_04885	COG0604	alcohol dehydrogenase
HB763_04910	COG2119	membrane
HB763_04925	COG3977	Valine--pyruvate aminotransferase
HB763_04930	COG0071	Belongs to the small heat shock protein (HSP20) family
HB763_04935	COG0187	DNA topoisomerase II activity
HB763_04945	COG0592	DNA-directed DNA polymerase activity
HB763_04965	COG1126	abc transporter atp-binding protein
HB763_04995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HB763_05010	COG1192	Involved in chromosome partitioning
HB763_05015	COG1475	DNA binding
HB763_05020	COG3312	ion transport
HB763_05050	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HB763_05060	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HB763_05070	COG0765	amino acid transport
HB763_05075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB763_05080	COG2814	Major facilitator Superfamily
HB763_05085	COG0583	DNA-binding transcription factor activity
HB763_05095	COG0129	dihydroxy-acid dehydratase activity
HB763_05100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HB763_05105	COG3978	acetolactate synthase activity
HB763_05115	COG0606	chelatase, subunit chli
HB763_05120	COG2199	diguanylate cyclase activity
HB763_05130	COG0204	Acyl-transferase
HB763_05135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB763_05140	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HB763_05150	COG3084	Protein conserved in bacteria
HB763_05160	COG4326	sporulation control protein
HB763_05165	COG1272	protein, Hemolysin III
HB763_05175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HB763_05180	COG0569	domain protein
HB763_05185	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HB763_05185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HB763_05195	COG0242	peptide deformylase activity
HB763_05205	COG0758	DNA mediated transformation
HB763_05215	COG0551	DNA topoisomerase type I activity
HB763_05220	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HB763_05225	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HB763_05250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HB763_05290	COG0583	DNA-binding transcription factor activity
HB763_05295	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HB763_05300	COG2960	long-chain fatty acid transporting porin activity
HB763_05305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB763_05310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB763_05355	COG0546	phosphoglycolate phosphatase activity
HB763_05360	COG4172	Belongs to the ABC transporter superfamily
HB763_05365	COG4166	transmembrane transport
HB763_05370	COG0601	transmembrane transport
HB763_05375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB763_05420	COG0800	Aldolase
HB763_05425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB763_05435	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HB763_05445	COG1522	sequence-specific DNA binding
HB763_05450	COG5001	Diguanylate cyclase
HB763_05450	COG5002	protein histidine kinase activity
HB763_05470	COG0589	response to stress
HB763_05475	COG1528	Iron-storage protein
HB763_05485	COG2081	HI0933 family
HB763_05505	COG1910	domain protein
HB763_05520	COG1322	Protein conserved in bacteria
HB763_05530	COG3165	ubiquinone biosynthetic process from chorismate
HB763_05545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HB763_05550	COG0805	protein transport
HB763_05555	COG0084	hydrolase, TatD family'
HB763_05570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HB763_05570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HB763_05575	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HB763_05605	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HB763_05615	COG2204	response regulator
HB763_05620	COG3852	Histidine kinase
HB763_05630	COG0174	glutamine synthetase
HB763_05635	COG1217	gtp-binding protein TYPA
HB763_05655	COG1490	D-aminoacyl-tRNA deacylase activity
HB763_05660	COG0456	acetyltransferase
HB763_05680	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HB763_05685	COG3031	protein transport across the cell outer membrane
HB763_05695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB763_05700	COG1459	type II secretion system
HB763_05705	COG2165	general secretion pathway protein
HB763_05710	COG2165	general secretion pathway protein
HB763_05715	COG2165	general secretion pathway protein
HB763_05720	COG4795	General secretion pathway protein
HB763_05725	COG3156	type II secretion system protein K
HB763_05730	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HB763_05735	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HB763_05745	COG1218	3'(2'),5'-bisphosphate nucleotidase
HB763_05750	COG0494	nUDIX hydrolase
HB763_05760	COG1040	competence protein
HB763_05775	COG2183	response to ionizing radiation
HB763_05785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB763_05800	COG2233	PERMEase
HB763_05810	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HB763_05815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB763_05820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HB763_05825	COG1758	RNA polymerase activity
HB763_05830	COG0194	GDP metabolic process
HB763_05845	COG0848	biopolymer transport protein
HB763_05850	COG0811	peptide transport
HB763_05870	COG4174	ABC transporter (Permease)
HB763_05875	COG4239	(ABC) transporter, permease
HB763_05880	COG0747	negative chemotaxis
HB763_05885	COG0444	Belongs to the ABC transporter superfamily
HB763_05890	COG4608	Belongs to the ABC transporter superfamily
HB763_05900	COG1561	YicC-like family, N-terminal region
HB763_05905	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HB763_05910	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HB763_05915	COG1560	Kdo2-lipid A biosynthetic process
HB763_05925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HB763_05970	COG1404	Belongs to the peptidase S8 family
HB763_06020	COG2194	sulfuric ester hydrolase activity
HB763_06040	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HB763_06055	COG0463	Glycosyl transferase, family 2
HB763_06060	COG0859	PFAM glycosyl transferase family 9
HB763_06065	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HB763_06070	COG3642	lipopolysaccharide core region biosynthetic process
HB763_06085	COG1519	Transferase
HB763_06090	COG0859	PFAM glycosyl transferase family 9
HB763_06100	COG1560	Kdo2-lipid A biosynthetic process
HB763_06110	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB763_06140	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HB763_06150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HB763_06160	COG2089	acid synthase
HB763_06170	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HB763_06195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HB763_06210	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HB763_06215	COG0149	triose-phosphate isomerase activity
HB763_06245	COG1494	fructose-1,6-bisphosphatase
HB763_06255	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HB763_06260	COG1575	Belongs to the MenA family. Type 1 subfamily
HB763_06280	COG1609	Transcriptional regulator
HB763_06285	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HB763_06305	COG0088	Forms part of the polypeptide exit tunnel
HB763_06390	COG1841	ribosomal large subunit assembly
HB763_06400	COG0201	protein transport
HB763_06405	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HB763_06410	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HB763_06415	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HB763_06425	COG0202	RNA polymerase activity
HB763_06430	COG0203	ribosomal protein L17
HB763_06440	COG0545	Peptidyl-prolyl cis-trans isomerase
HB763_06465	COG2153	protein acetylation
HB763_06470	COG0513	Belongs to the DEAD box helicase family
HB763_06480	COG0737	Belongs to the 5'-nucleotidase family
HB763_06485	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HB763_06485	COG1648	precorrin-2 dehydrogenase activity
HB763_06500	COG3273	potassium ion transport
HB763_06500	COG0471	metal ion transport
HB763_06505	COG0529	Catalyzes the synthesis of activated sulfate
HB763_06525	COG1136	(ABC) transporter
HB763_06540	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HB763_06550	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB763_06565	COG2105	PFAM AIG2 family protein
HB763_06575	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HB763_06585	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HB763_06590	COG0163	prenyltransferase activity
HB763_06595	COG4143	(ABC) transporter
HB763_06600	COG1178	ABC-type Fe3 transport system permease component
HB763_06605	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HB763_06620	COG2358	TRAP transporter, solute receptor (TAXI family
HB763_06640	COG0142	geranyltranstransferase activity
HB763_06645	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HB763_06660	COG2966	Psort location CytoplasmicMembrane, score
HB763_06665	COG3610	response to peptide
HB763_06670	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HB763_06690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HB763_06695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB763_06700	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HB763_06705	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HB763_06725	COG0473	3-isopropylmalate dehydrogenase activity
HB763_06730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HB763_06750	COG0583	DNA-binding transcription factor activity
HB763_06755	COG1022	Amp-dependent synthetase and ligase
HB763_06760	COG0028	Belongs to the TPP enzyme family
HB763_06765	COG0440	acetolactate synthase activity
HB763_06770	COG3706	GGDEF domain
HB763_06780	COG0469	pyruvate kinase activity
HB763_06785	COG1349	DNA-binding transcription factor activity
HB763_06790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HB763_06835	COG0358	DNA primase activity
HB763_06840	COG1610	YqeY-like protein
HB763_06845	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HB763_06850	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HB763_06855	COG0596	Alpha beta hydrolase
HB763_06865	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HB763_06870	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HB763_06885	COG3267	Type II secretory pathway component ExeA
HB763_06885	COG3409	Peptidoglycan-binding domain 1 protein
HB763_06895	COG0405	Gamma-glutamyltransferase
HB763_06900	COG4991	sh3 domain protein
HB763_06905	COG0306	phosphate transporter
HB763_06910	COG1392	Phosphate transport regulator
HB763_06915	COG3025	triphosphatase activity
HB763_06920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HB763_06930	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HB763_06940	COG1538	Outer membrane efflux protein
HB763_06945	COG0494	nUDIX hydrolase
HB763_06950	COG3151	Protein conserved in bacteria
HB763_06960	COG3150	esterase
HB763_06970	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HB763_06975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HB763_06980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HB763_06985	COG3105	Protein conserved in bacteria
HB763_06990	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HB763_07005	COG0723	plastoquinol--plastocyanin reductase activity
HB763_07010	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HB763_07015	COG2857	Cytochrome c1
HB763_07020	COG0625	glutathione transferase activity
HB763_07025	COG2969	positive regulation of protein catabolic process
HB763_07030	COG2823	Periplasmic or secreted lipoprotein
HB763_07035	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HB763_07050	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HB763_07065	COG3116	cell division
HB763_07070	COG0768	penicillin binding
HB763_07075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HB763_07080	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HB763_07095	COG0772	Belongs to the SEDS family
HB763_07110	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HB763_07115	COG0849	cell division
HB763_07120	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HB763_07140	COG0494	nUDIX hydrolase
HB763_07150	COG0505	Belongs to the CarA family
HB763_07155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HB763_07160	COG0730	response to heat
HB763_07165	COG0583	DNA-binding transcription factor activity
HB763_07170	COG2860	membrane
HB763_07195	COG0493	'glutamate synthase
HB763_07200	COG0070	glutamate synthase
HB763_07200	COG0067	glutamate synthase
HB763_07200	COG0069	glutamate synthase activity
HB763_07210	COG0070	glutamate synthase
HB763_07210	COG0069	glutamate synthase activity
HB763_07210	COG0067	glutamate synthase
HB763_07215	COG1242	4 iron, 4 sulfur cluster binding
HB763_07220	COG2203	Gaf domain
HB763_07220	COG3706	GGDEF domain
HB763_07220	COG4251	negative regulation of phosphorylation
HB763_07220	COG5001	Diguanylate cyclase
HB763_07225	COG5002	protein histidine kinase activity
HB763_07225	COG2198	Histidine kinase
HB763_07225	COG0784	Response regulator, receiver
HB763_07235	COG0745	RESPONSE REGULATOR receiver
HB763_07245	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HB763_07260	COG0083	homoserine kinase activity
HB763_07265	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HB763_07270	COG0431	NADPH-dependent FMN reductase
HB763_07295	COG1115	amino acid carrier protein
HB763_07300	COG3022	response to hydroperoxide
HB763_07310	COG0513	Belongs to the DEAD box helicase family
HB763_07325	COG0716	FMN binding
HB763_07330	COG4974	Belongs to the 'phage' integrase family
HB763_07335	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB763_07340	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HB763_07365	COG0667	Aldo Keto reductase
HB763_07390	COG0730	response to heat
HB763_07405	COG1283	sodium-dependent phosphate transmembrane transporter activity
HB763_07410	COG0583	DNA-binding transcription factor activity
HB763_07415	COG0640	Transcriptional regulator
HB763_07420	COG0268	Binds directly to 16S ribosomal RNA
HB763_07425	COG0728	peptidoglycan biosynthetic process
HB763_07430	COG0196	riboflavin kinase activity
HB763_07445	COG1047	Peptidyl-prolyl cis-trans
HB763_07450	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HB763_07455	COG3279	Response regulator of the LytR AlgR family
HB763_07460	COG3275	phosphorelay sensor kinase activity
HB763_07465	COG1966	Carbon starvation protein
HB763_07485	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HB763_07495	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB763_07500	COG0287	Prephenate dehydrogenase
HB763_07500	COG1605	Chorismate mutase
HB763_07505	COG0739	heme binding
HB763_07515	COG0488	(ABC) transporter
HB763_07530	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
HB763_07535	COG0077	Prephenate dehydratase
HB763_07535	COG1605	Chorismate mutase
HB763_07540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HB763_07545	COG0741	lytic transglycosylase activity
HB763_07550	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB763_07555	COG0564	pseudouridine synthase activity
HB763_07560	COG1496	oxidoreductase activity
HB763_07565	COG0542	response to heat
HB763_07620	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB763_07625	COG0826	peptidase U32
HB763_07635	COG0745	RESPONSE REGULATOR receiver
HB763_07640	COG5002	protein histidine kinase activity
HB763_07650	COG0248	Ppx GppA phosphatase
HB763_07655	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HB763_07660	COG0573	inorganic phosphate transmembrane transporter activity
HB763_07665	COG0581	inorganic phosphate transmembrane transporter activity
HB763_07670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HB763_07675	COG0704	Plays a role in the regulation of phosphate uptake
HB763_07690	COG0450	alkyl hydroperoxide reductase
HB763_07695	COG0583	DNA-binding transcription factor activity
HB763_07700	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HB763_07710	COG0517	IMP dehydrogenase activity
HB763_07730	COG1862	Preprotein translocase
HB763_07735	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB763_07740	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB763_07745	COG0483	inositol monophosphate 1-phosphatase activity
HB763_07750	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HB763_07765	COG0822	iron-sulfur transferase activity
HB763_07770	COG0316	Belongs to the HesB IscA family
HB763_07785	COG0633	Ferredoxin
HB763_07790	COG2975	iron-sulfur cluster assembly
HB763_07825	COG2976	Protein conserved in bacteria
HB763_07830	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB763_07845	COG2199	diguanylate cyclase activity
HB763_07845	COG2203	Gaf domain
HB763_07860	COG0517	IMP dehydrogenase activity
HB763_07860	COG0516	GMP reductase activity
HB763_07870	COG1757	Na H antiporter
HB763_07880	COG1584	GPR1 FUN34 yaaH family protein
HB763_07885	COG1115	amino acid carrier protein
HB763_07895	COG0583	DNA-binding transcription factor activity
HB763_07900	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HB763_07905	COG0668	transmembrane transport
HB763_07920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HB763_07940	COG1289	transmembrane transporter activity
HB763_07945	COG0583	DNA-binding transcription factor activity
HB763_07960	COG2867	negative regulation of translational initiation
HB763_07965	COG2914	Belongs to the UPF0125 (RnfH) family
HB763_07970	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB763_07975	COG0456	acetyltransferase
HB763_07980	COG0497	DNA recombination
HB763_07995	COG1301	dicarboxylic acid transport
HB763_08000	COG0443	Heat shock 70 kDa protein
HB763_08015	COG4969	Belongs to the N-Me-Phe pilin family
HB763_08035	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HB763_08040	COG0590	tRNA wobble adenosine to inosine editing
HB763_08050	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HB763_08050	COG0047	phosphoribosylformylglycinamidine synthase activity
HB763_08135	COG2195	Cleaves the N-terminal amino acid of tripeptides
HB763_08140	COG2252	PERMEase
HB763_08150	COG1073	alpha beta
HB763_08165	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HB763_08170	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HB763_08175	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HB763_08175	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HB763_08200	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HB763_08205	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HB763_08215	COG0142	geranyltranstransferase activity
HB763_08225	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HB763_08240	COG0583	DNA-binding transcription factor activity
HB763_08250	COG2363	Small membrane protein
HB763_08270	COG1611	Belongs to the LOG family
HB763_08295	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
HB763_08310	COG1464	Belongs to the NlpA lipoprotein family
HB763_08315	COG2011	ABC-type metal ion transport system permease component
HB763_08320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HB763_08325	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HB763_08335	COG1263	PTS System
HB763_08335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB763_08340	COG0366	Alpha amylase catalytic
HB763_08355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HB763_08360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HB763_08380	COG1686	Belongs to the peptidase S11 family
HB763_08385	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HB763_08390	COG0772	Belongs to the SEDS family
HB763_08395	COG0768	penicillin binding
HB763_08405	COG0799	negative regulation of ribosome biogenesis
HB763_08410	COG1466	dna polymerase III delta subunit
HB763_08415	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
HB763_08425	COG2888	peptidyl-tyrosine sulfation
HB763_08430	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HB763_08435	COG4535	Mg2 and Co2 transporter CorC
HB763_08445	COG1702	phosphate starvation-inducible protein PhoH
HB763_08455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB763_08575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HB763_08600	COG2890	protein-(glutamine-N5) methyltransferase activity
HB763_08605	COG3094	Invasion gene expression up-regulator, SirB
HB763_08610	COG2912	Transglutaminase-like superfamily
HB763_08620	COG0737	Belongs to the 5'-nucleotidase family
HB763_08625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HB763_08630	COG1187	pseudouridine synthase activity
HB763_08635	COG2840	Smr protein MutS2
HB763_08675	COG2217	Heavy metal translocating P-type atpase
HB763_08675	COG2608	mercury ion transmembrane transporter activity
HB763_08685	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HB763_08740	COG0784	Response regulator, receiver
HB763_08740	COG0835	chemotaxis
HB763_08745	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HB763_08750	COG1815	bacterial-type flagellum-dependent cell motility
HB763_08755	COG1558	bacterial-type flagellum-dependent cell motility
HB763_08765	COG1749	Flagellar hook protein flgE
HB763_08770	COG4787	bacterial-type flagellum-dependent cell motility
HB763_08780	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HB763_08785	COG1706	bacterial-type flagellum-dependent cell motility
HB763_08790	COG1705	Flagellar rod assembly protein muramidase FlgJ
HB763_08790	COG3951	Flagellar rod assembly protein muramidase FlgJ
HB763_08805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB763_08810	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB763_08815	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB763_08820	COG2190	(PTS) system
HB763_08825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HB763_08830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB763_08835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HB763_08840	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
HB763_08865	COG3385	transposase activity
HB763_08880	COG0330	HflC and HflK could
HB763_08885	COG3118	belongs to the thioredoxin family
HB763_08895	COG0300	oxidoreductase activity
HB763_08900	COG1090	epimerase
HB763_08910	COG0622	Phosphoesterase
HB763_08930	COG3710	Transcriptional regulator
HB763_08945	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HB763_08950	COG3104	oligopeptide transport
HB763_08955	COG0250	Participates in transcription elongation, termination and antitermination
HB763_08960	COG0367	asparagine synthase
HB763_08965	COG4651	solute:proton antiporter activity
HB763_08965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HB763_08970	COG1846	Transcriptional regulator
HB763_08970	COG1940	carbohydrate kinase activity
HB763_08975	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HB763_08980	COG1263	PTS System
HB763_08980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB763_08980	COG2190	(PTS) system
HB763_08990	COG2165	general secretion pathway protein
HB763_08995	COG0735	belongs to the Fur family
HB763_09015	COG0596	Alpha beta hydrolase
HB763_09020	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HB763_09025	COG0033	Phosphoglucomutase
HB763_09035	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HB763_09050	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HB763_09055	COG1053	succinate dehydrogenase
HB763_09065	COG0567	Dehydrogenase, E1 component
HB763_09070	COG0508	dehydrogenase complex catalyzes the overall conversion of
HB763_09085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB763_09090	COG1121	(ABC) transporter
HB763_09095	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HB763_09100	COG4977	sequence-specific DNA binding
HB763_09105	COG1918	ferrous iron import across plasma membrane
HB763_09135	COG3102	Protein conserved in bacteria
HB763_09150	COG0788	formyltetrahydrofolate deformylase activity
HB763_09155	COG1199	ATP-dependent helicase activity
HB763_09160	COG1214	PFAM Peptidase M22, glycoprotease
HB763_09170	COG3065	identical protein binding
HB763_09175	COG2267	carboxylic ester hydrolase activity
HB763_09180	COG0318	PFAM AMP-dependent synthetase and ligase
HB763_09185	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HB763_09190	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HB763_09195	COG2894	cell division
HB763_09210	COG2951	lytic endotransglycosylase activity
HB763_09220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB763_09235	COG2226	methyltransferase
HB763_09250	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_09260	COG1169	isochorismate synthase
HB763_09265	COG1021	2,3-dihydroxybenzoate-AMP ligase
HB763_09270	COG1535	isochorismatase
HB763_09270	COG3433	isochorismatase activity
HB763_09275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB763_09275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB763_09285	COG2977	Belongs to the P-Pant transferase superfamily
HB763_09290	COG4771	TonB-dependent receptor
HB763_09300	COG0513	Belongs to the DEAD box helicase family
HB763_09305	COG0569	domain protein
HB763_09310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HB763_09330	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HB763_09335	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HB763_09340	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HB763_09375	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HB763_09380	COG0776	regulation of translation
HB763_09385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB763_09390	COG1555	photosystem II stabilization
HB763_09410	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HB763_09415	COG0436	Aminotransferase
HB763_09420	COG1169	isochorismate synthase
HB763_09430	COG0596	Alpha beta hydrolase
HB763_09435	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HB763_09450	COG2190	(PTS) system
HB763_09450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB763_09450	COG1263	PTS System
HB763_09455	COG0583	DNA-binding transcription factor activity
HB763_09465	COG2855	membrane
HB763_09520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB763_09540	COG1522	sequence-specific DNA binding
HB763_09545	COG1946	Acyl-CoA thioesterase
HB763_09550	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HB763_09565	COG3706	GGDEF domain
HB763_09600	COG1061	Type III restriction enzyme res subunit
HB763_09615	COG0732	type I restriction modification DNA specificity domain
HB763_09670	COG3344	reverse transcriptase
HB763_09715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB763_09720	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HB763_09725	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
HB763_09730	COG0516	GMP reductase activity
HB763_09730	COG0517	IMP dehydrogenase activity
HB763_09740	COG2217	Heavy metal translocating P-type atpase
HB763_09760	COG0537	adenosine 5'-monophosphoramidase activity
HB763_09790	COG1252	NADH dehydrogenase
HB763_09805	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HB763_09815	COG4591	ABC-type transport system involved in lipoprotein release permease component
HB763_09820	COG1136	(ABC) transporter
HB763_09825	COG4591	ABC-type transport system involved in lipoprotein release permease component
HB763_09835	COG0658	competence protein
HB763_09835	COG2333	competence protein COMEC
HB763_09840	COG1132	(ABC) transporter
HB763_09860	COG2719	SpoVR family
HB763_09865	COG2718	Belongs to the UPF0229 family
HB763_09870	COG2766	serine protein kinase
HB763_09885	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HB763_09895	COG1882	Formate acetyltransferase
HB763_09930	COG0708	Exodeoxyribonuclease III
HB763_09940	COG3923	Primosomal replication protein n
HB763_09945	COG0730	response to heat
HB763_09950	COG1199	ATP-dependent helicase activity
HB763_09960	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HB763_09965	COG1187	pseudouridine synthase activity
HB763_09975	COG1278	Cold shock
HB763_09985	COG0542	response to heat
HB763_09990	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HB763_10020	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HB763_10025	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HB763_10030	COG0297	glycogen (starch) synthase activity
HB763_10050	COG3070	regulator of competence-specific genes
HB763_10065	COG0745	RESPONSE REGULATOR receiver
HB763_10070	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HB763_10075	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB763_10085	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HB763_10090	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HB763_10110	COG0189	ligase activity
HB763_10110	COG4067	protein conserved in archaea
HB763_10125	COG1801	Protein of unknown function DUF72
HB763_10140	COG0840	transmembrane signaling receptor activity
HB763_10145	COG0632	four-way junction helicase activity
HB763_10155	COG1271	oxidase subunit
HB763_10160	COG1294	oxidase, subunit
HB763_10165	COG4890	Cyd operon protein YbgT
HB763_10175	COG0824	Thioesterase
HB763_10180	COG0811	peptide transport
HB763_10195	COG0823	Involved in the tonB-independent uptake of proteins
HB763_10200	COG2885	chlorophyll binding
HB763_10205	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HB763_10220	COG3766	membrane
HB763_10230	COG0754	glutathionylspermidine amidase activity
HB763_10240	COG0784	Response regulator, receiver
HB763_10240	COG2205	protein histidine kinase activity
HB763_10255	COG0514	ATP-dependent DNA helicase (RecQ)
HB763_10350	COG4669	(LipO)protein
HB763_10380	COG3177	Filamentation induced by cAMP protein fic
HB763_10390	COG0583	DNA-binding transcription factor activity
HB763_10395	COG4792	protein secretion
HB763_10400	COG4791	protein targeting
HB763_10405	COG4794	Type iii secretion
HB763_10410	COG4790	Type iii secretion
HB763_10480	COG0457	Tetratricopeptide repeat
HB763_10525	COG2824	Alkylphosphonate utilization operon protein PhnA
HB763_10535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB763_10540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB763_10555	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HB763_10575	COG3568	Endonuclease Exonuclease Phosphatase
HB763_10590	COG4934	collagen metabolic process
HB763_10595	COG0402	S-adenosylhomocysteine deaminase activity
HB763_10620	COG0583	DNA-binding transcription factor activity
HB763_10630	COG0686	Belongs to the AlaDH PNT family
HB763_10640	COG1674	ftsk spoiiie
HB763_10650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HB763_10660	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HB763_10680	COG2226	methyltransferase
HB763_10705	COG0300	oxidoreductase activity
HB763_10720	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HB763_10740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HB763_10760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB763_10770	COG1757	Na H antiporter
HB763_10780	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HB763_10790	COG0131	Imidazoleglycerol-phosphate dehydratase
HB763_10790	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HB763_10795	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HB763_10800	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HB763_10810	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HB763_10810	COG0140	phosphoribosyl-ATP diphosphatase activity
HB763_10815	COG3012	SEC-C Motif Domain Protein
HB763_10820	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HB763_10825	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HB763_10830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HB763_10835	COG0215	cysteine-tRNA ligase activity
HB763_10840	COG1435	thymidine kinase activity
HB763_10845	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HB763_10865	COG2116	formate transmembrane transporter activity
HB763_10875	COG0390	transport system, permease component
HB763_10880	COG4459	periplasmic nitrate reductase
HB763_10885	COG3005	denitrification pathway
HB763_10890	COG0243	molybdopterin cofactor binding
HB763_10905	COG1121	(ABC) transporter
HB763_10910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB763_10915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB763_10920	COG1227	inorganic diphosphatase activity
HB763_10930	COG4172	Belongs to the ABC transporter superfamily
HB763_10940	COG4171	peptide transport system, permease
HB763_10945	COG4168	peptide transport system, permease
HB763_10955	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HB763_10960	COG1842	Phage shock protein A
HB763_10970	COG1983	PspC domain protein
HB763_10980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB763_10990	COG2818	Glycosylase
HB763_11010	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HB763_11015	COG0626	cystathionine gamma-synthase activity
HB763_11025	COG0733	neurotransmitter:sodium symporter activity
HB763_11030	COG0564	pseudouridine synthase activity
HB763_11045	COG2814	Major facilitator Superfamily
HB763_11055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HB763_11060	COG4136	ATPase activity
HB763_11065	COG4135	transport system, permease component
HB763_11070	COG4134	Bacterial extracellular solute-binding protein
HB763_11085	COG0659	secondary active sulfate transmembrane transporter activity
HB763_11095	COG3313	Fe-S protein
HB763_11150	COG1061	Type III restriction enzyme res subunit
HB763_11155	COG1187	pseudouridine synthase activity
HB763_11160	COG2814	Major facilitator Superfamily
HB763_11170	COG0702	epimerase
HB763_11175	COG0534	Mate efflux family protein
HB763_11180	COG4181	ATPase activity
HB763_11200	COG3335	DDE superfamily endonuclease
HB763_11215	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HB763_11225	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HB763_11235	COG1737	Transcriptional regulator
HB763_11240	COG0076	glutamate decarboxylase activity
HB763_11250	COG2431	L-lysine efflux transmembrane transporter activity
HB763_11260	COG3070	regulator of competence-specific genes
HB763_11275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB763_11275	COG4191	Histidine kinase
HB763_11285	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HB763_11310	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HB763_11315	COG4988	ABC transporter
HB763_11320	COG0492	ferredoxin-NADP+ reductase activity
HB763_11325	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HB763_11345	COG0471	metal ion transport
HB763_11350	COG2949	membrane
HB763_11360	COG1643	Atp-dependent helicase
HB763_11465	COG0277	FAD linked oxidase domain protein
HB763_11465	COG0247	lactate metabolic process
HB763_11510	COG2986	histidine ammonia-lyase
HB763_11520	COG0010	Belongs to the arginase family
HB763_11530	COG2188	Transcriptional regulator
HB763_11565	COG0641	radical SAM
HB763_11570	COG3119	arylsulfatase activity
HB763_11585	COG0251	oxidation-reduction process
HB763_11635	COG0072	phenylalanine-tRNA ligase activity
HB763_11635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HB763_11640	COG1535	isochorismatase
HB763_11640	COG3433	isochorismatase activity
HB763_11645	COG1132	(ABC) transporter
HB763_11650	COG2375	cellular response to nickel ion
HB763_11650	COG1132	(ABC) transporter
HB763_11660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB763_11680	COG4774	siderophore transport
HB763_11685	COG4607	ABC-type enterochelin transport system periplasmic component
HB763_11690	COG4605	iron ion homeostasis
HB763_11695	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB763_11745	COG1346	cytolysis
HB763_11755	COG2925	Exonuclease
HB763_11765	COG1823	symporter activity
HB763_11770	COG0702	epimerase
HB763_11775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HB763_11785	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HB763_11795	COG2062	phosphohistidine phosphatase, SixA
HB763_11810	COG4139	cobalamin transport
HB763_11840	COG0583	DNA-binding transcription factor activity
HB763_11850	COG1451	nucleotide metabolic process
HB763_11930	COG2195	Cleaves the N-terminal amino acid of tripeptides
HB763_11945	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HB763_11955	COG0625	glutathione transferase activity
HB763_12000	COG0318	PFAM AMP-dependent synthetase and ligase
HB763_12015	COG0668	transmembrane transport
HB763_12020	COG3247	response to pH
HB763_12035	COG1846	Transcriptional regulator
HB763_12090	COG4999	Histidine kinase
HB763_12090	COG2205	protein histidine kinase activity
HB763_12090	COG3437	response regulator, receiver
HB763_12090	COG3850	Histidine kinase
HB763_12095	COG5001	Diguanylate cyclase
HB763_12095	COG3300	MHYT domain
HB763_12110	COG0116	Belongs to the methyltransferase superfamily
HB763_12110	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HB763_12120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HB763_12125	COG1215	transferase activity, transferring glycosyl groups
HB763_12130	COG0438	transferase activity, transferring glycosyl groups
HB763_12160	COG0438	transferase activity, transferring glycosyl groups
HB763_12165	COG0438	transferase activity, transferring glycosyl groups
HB763_12170	COG2204	response regulator
HB763_12190	COG2885	chlorophyll binding
HB763_12200	COG1793	dna ligase
HB763_12210	COG0534	Mate efflux family protein
HB763_12215	COG0307	riboflavin synthase, alpha
HB763_12225	COG3001	Fructosamine kinase
HB763_12230	COG2201	protein-glutamate methylesterase activity
HB763_12235	COG3706	GGDEF domain
HB763_12245	COG0791	NLP P60 protein
HB763_12250	COG0840	transmembrane signaling receptor activity
HB763_12295	COG3148	PFAM DTW domain containing protein
HB763_12300	COG1940	carbohydrate kinase activity
HB763_12310	COG0303	'Molybdopterin
HB763_12320	COG3842	ATPase activity
HB763_12325	COG4662	Binding-protein-dependent transport system inner membrane component
HB763_12335	COG2204	response regulator
HB763_12340	COG4191	Histidine kinase
HB763_12355	COG0488	(ABC) transporter
HB763_12360	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HB763_12380	COG3381	protein complex oligomerization
HB763_12390	COG0243	molybdopterin cofactor binding
HB763_12390	COG3383	formate dehydrogenase (NAD+) activity
HB763_12395	COG0437	4 iron, 4 sulfur cluster binding
HB763_12410	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HB763_12415	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HB763_12425	COG1177	transmembrane transport
HB763_12435	COG3842	ATPase activity
HB763_12460	COG0589	response to stress
HB763_12465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB763_12480	COG2217	Heavy metal translocating P-type atpase
HB763_12490	COG2010	Cytochrome c
HB763_12505	COG3278	Belongs to the heme-copper respiratory oxidase family
HB763_12520	COG2205	protein histidine kinase activity
HB763_12520	COG0784	Response regulator, receiver
HB763_12550	COG1067	ATP-dependent peptidase activity
HB763_12570	COG0488	(ABC) transporter
HB763_12595	COG2902	Dehydrogenase
HB763_12605	COG0308	aminopeptidase N
HB763_12620	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HB763_12625	COG1956	GAF domain-containing protein
HB763_12630	COG1132	(ABC) transporter
HB763_12635	COG2995	paraquat-inducible protein a
HB763_12640	COG3008	intermembrane lipid transfer
HB763_12665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB763_12680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB763_12685	COG4597	amino acid ABC transporter
HB763_12690	COG0765	amino acid transport
HB763_12695	COG1126	abc transporter atp-binding protein
HB763_12700	COG0670	Belongs to the BI1 family
HB763_12705	COG2920	part of a sulfur-relay system
HB763_12710	COG1254	Belongs to the acylphosphatase family
HB763_12775	COG3706	GGDEF domain
HB763_12785	COG0602	queuosine metabolic process
HB763_12790	COG0561	phosphatase activity
HB763_12825	COG2828	Protein conserved in bacteria
HB763_12835	COG0372	Belongs to the citrate synthase family
HB763_12840	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HB763_12850	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HB763_12890	COG0730	response to heat
HB763_12900	COG2358	TRAP transporter, solute receptor (TAXI family
HB763_12905	COG1012	belongs to the aldehyde dehydrogenase family
HB763_12910	COG3284	Transcriptional regulator
HB763_12920	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HB763_12925	COG0363	glucosamine-6-phosphate deaminase activity
HB763_12930	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HB763_12935	COG4565	transcriptional regulatory protein
HB763_12940	COG3290	protein histidine kinase activity
HB763_12960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB763_13010	COG0517	IMP dehydrogenase activity
HB763_13010	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HB763_13015	COG2801	Transposase and inactivated derivatives
HB763_13050	COG3335	DDE superfamily endonuclease
HB763_13155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HB763_13165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HB763_13175	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HB763_13200	COG0583	DNA-binding transcription factor activity
HB763_13230	COG0534	Mate efflux family protein
HB763_13440	COG1280	lysine exporter protein (LysE YggA)
HB763_13450	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HB763_13455	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HB763_13500	COG1404	Belongs to the peptidase S8 family
HB763_13505	COG1858	cytochrome C peroxidase
HB763_13515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB763_13525	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HB763_13535	COG0215	cysteine-tRNA ligase activity
HB763_13550	COG1368	sulfuric ester hydrolase activity
HB763_13575	COG1115	amino acid carrier protein
HB763_13605	COG1280	lysine exporter protein (LysE YggA)
HB763_13610	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HB763_13635	COG1280	lysine exporter protein (LysE YggA)
HB763_13645	COG0531	amino acid
HB763_13675	COG3063	Type IV pilus biogenesis stability protein PilW
HB763_13700	COG1643	Atp-dependent helicase
HB763_13735	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HB763_13740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB763_13775	COG3227	Zinc metalloprotease (Elastase)
HB763_13805	COG3706	GGDEF domain
HB763_13815	COG0443	Heat shock 70 kDa protein
HB763_13820	COG0443	Heat shock 70 kDa protein
HB763_13845	COG0583	DNA-binding transcription factor activity
HB763_13850	COG2165	general secretion pathway protein
HB763_13855	COG1132	(ABC) transporter
HB763_13860	COG1132	(ABC) transporter
HB763_13880	COG0814	amino acid
HB763_13885	COG1454	alcohol dehydrogenase
HB763_13890	COG4221	oxidoreductase activity
HB763_13895	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HB763_13905	COG0861	Integral membrane protein TerC family
HB763_13915	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HB763_13920	COG1328	CTP reductase activity
HB763_13925	COG1280	lysine exporter protein (LysE YggA)
HB763_13970	COG3340	Belongs to the peptidase S51 family
HB763_13995	COG2977	Belongs to the P-Pant transferase superfamily
HB763_14010	COG0300	oxidoreductase activity
HB763_14010	COG0318	PFAM AMP-dependent synthetase and ligase
HB763_14010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB763_14010	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_14010	COG3321	synthase
HB763_14025	COG1216	Glycosyl transferase, family 2
HB763_14040	COG0284	orotidine-5'-phosphate decarboxylase activity
HB763_14045	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HB763_14055	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HB763_14060	COG0284	orotidine-5'-phosphate decarboxylase activity
HB763_14110	COG1683	Conserved Protein
HB763_14145	COG1192	Involved in chromosome partitioning
HB763_14160	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HB763_14170	COG3335	DDE superfamily endonuclease
HB763_14255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB763_14270	COG3106	COG3106 Predicted ATPase
HB763_14285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HB763_14290	COG0784	Response regulator, receiver
HB763_14290	COG2205	protein histidine kinase activity
HB763_14305	COG0814	amino acid
HB763_14310	COG1760	l-serine dehydratase
HB763_14315	COG3300	MHYT domain
HB763_14315	COG5001	Diguanylate cyclase
HB763_14330	COG2197	response regulator
HB763_14335	COG0720	synthase
HB763_14345	COG0017	Asparaginyl-tRNA synthetase
HB763_14360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB763_14380	COG1448	Aminotransferase
HB763_14400	COG0840	transmembrane signaling receptor activity
HB763_14405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB763_14410	COG1846	Transcriptional regulator
HB763_14435	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HB763_14450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HB763_14455	COG3108	Peptidase M15
HB763_14460	COG2989	Protein conserved in bacteria
HB763_14495	COG3088	subunit of a heme lyase
HB763_14495	COG4235	cytochrome complex assembly
HB763_14525	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB763_14530	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB763_14540	COG1058	Belongs to the CinA family
HB763_14540	COG1546	Belongs to the CinA family
HB763_14555	COG0019	diaminopimelate decarboxylase activity
HB763_14595	COG0322	excinuclease ABC activity
HB763_14600	COG2197	response regulator
HB763_14605	COG0417	DNA replication proofreading
HB763_14625	COG1187	pseudouridine synthase activity
HB763_14635	COG0009	L-threonylcarbamoyladenylate synthase
HB763_14640	COG0613	PHP domain protein
HB763_14650	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HB763_14655	COG0512	Glutamine amidotransferase of anthranilate synthase
HB763_14665	COG0134	indole-3-glycerol-phosphate synthase activity
HB763_14665	COG0135	phosphoribosylanthranilate isomerase activity
HB763_14675	COG0159	tryptophan synthase activity
HB763_14680	COG1301	dicarboxylic acid transport
HB763_14710	COG2350	Protein conserved in bacteria
HB763_14740	COG1716	ATPase activity
HB763_14740	COG5001	Diguanylate cyclase
HB763_14745	COG1032	radical SAM domain protein
HB763_14775	COG2175	clavaminate synthase activity
HB763_14790	COG0840	transmembrane signaling receptor activity
HB763_14800	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HB763_14805	COG0463	Glycosyl transferase, family 2
HB763_14810	COG0745	RESPONSE REGULATOR receiver
HB763_14815	COG3850	Histidine kinase
HB763_14815	COG5002	protein histidine kinase activity
HB763_14860	COG3615	Tellurite resistance protein tehB
HB763_14870	COG2207	Transcriptional regulator
HB763_14870	COG3708	Transcriptional regulator
HB763_14880	COG1217	gtp-binding protein TYPA
HB763_14890	COG2176	DNA-directed DNA polymerase activity
HB763_14905	COG0577	efflux transmembrane transporter activity
HB763_14905	COG1136	(ABC) transporter
HB763_14910	COG0577	efflux transmembrane transporter activity
HB763_14910	COG1136	(ABC) transporter
HB763_14915	COG0577	efflux transmembrane transporter activity
HB763_14925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB763_14935	COG1073	alpha beta
HB763_14935	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
HB763_14935	COG3064	Membrane
HB763_14950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HB763_14960	COG3118	belongs to the thioredoxin family
HB763_14965	COG4232	protein-disulfide reductase activity
HB763_14980	COG2995	paraquat-inducible protein a
HB763_14985	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HB763_14985	COG3008	intermembrane lipid transfer
HB763_14990	COG3009	Protein conserved in bacteria
HB763_15005	COG4166	transmembrane transport
HB763_15015	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HB763_15020	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HB763_15030	COG0539	negative regulation of cytoplasmic translation
HB763_15040	COG0616	signal peptide processing
HB763_15045	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_15065	COG0784	Response regulator, receiver
HB763_15065	COG0835	chemotaxis
HB763_15070	COG1940	carbohydrate kinase activity
HB763_15095	COG4667	esterase of the alpha-beta hydrolase superfamily
HB763_15110	COG0733	neurotransmitter:sodium symporter activity
HB763_15130	COG1263	PTS System
HB763_15130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB763_15135	COG0084	hydrolase, TatD family'
HB763_15150	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HB763_15180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HB763_15195	COG1399	metal-binding, possibly nucleic acid-binding protein
HB763_15200	COG0424	maF-like protein
HB763_15205	COG0564	pseudouridine synthase activity
HB763_15210	COG1530	ribonuclease E activity
HB763_15215	COG0659	secondary active sulfate transmembrane transporter activity
HB763_15220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HB763_15225	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HB763_15255	COG2186	Transcriptional regulator
HB763_15265	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HB763_15270	COG0653	protein targeting
HB763_15275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HB763_15290	COG1122	ATPase activity
HB763_15295	COG4120	Belongs to the binding-protein-dependent transport system permease family
HB763_15315	COG0857	belongs to the CobB CobQ family
HB763_15315	COG0280	phosphate acetyltransferase
HB763_15320	COG0435	Glutathione S-transferase
HB763_15330	COG0444	Belongs to the ABC transporter superfamily
HB763_15335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB763_15340	COG0601	transmembrane transport
HB763_15350	COG0314	molybdopterin synthase activity
HB763_15355	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HB763_15365	COG0521	Mo-molybdopterin cofactor biosynthetic process
HB763_15370	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HB763_15375	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HB763_15390	COG0556	nucleotide-excision repair
HB763_15450	COG4657	Part of a membrane complex involved in electron transport
HB763_15460	COG4656	Part of a membrane complex involved in electron transport
HB763_15465	COG4658	electron transport chain
HB763_15470	COG4659	FMN binding
HB763_15475	COG4660	Part of a membrane complex involved in electron transport
HB763_15480	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HB763_15515	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HB763_15595	COG2261	transglycosylase associated protein
HB763_15690	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HB763_15765	COG0346	lactoylglutathione lyase activity
HB763_15775	COG2885	chlorophyll binding
HB763_15785	COG2056	Na+-H+ antiporter family
HB763_15800	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HB763_15815	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_15820	COG1454	alcohol dehydrogenase
HB763_15820	COG1012	belongs to the aldehyde dehydrogenase family
HB763_15825	COG2095	MarC family integral membrane protein
HB763_15830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB763_15835	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HB763_15840	COG1757	Na H antiporter
HB763_15865	COG3083	sulfuric ester hydrolase activity
HB763_15880	COG4269	membrane
HB763_15890	COG0123	including yeast histone deacetylase and acetoin utilization protein
HB763_15905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HB763_15910	COG0778	Nitroreductase
HB763_15915	COG1902	pentaerythritol trinitrate reductase activity
HB763_15915	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB763_15920	COG0616	signal peptide processing
HB763_15925	COG0252	asparaginase activity
HB763_15930	COG3139	Protein of unknown function (DUF1315)
HB763_15940	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB763_15945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HB763_15970	COG0765	amino acid transport
HB763_15975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB763_15980	COG0765	amino acid transport
HB763_15985	COG1126	abc transporter atp-binding protein
HB763_15995	COG1979	alcohol dehydrogenase
HB763_16000	COG2207	Transcriptional regulator
HB763_16010	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HB763_16020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB763_16035	COG3437	response regulator, receiver
HB763_16040	COG0546	phosphoglycolate phosphatase activity
HB763_16050	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HB763_16055	COG0513	Belongs to the DEAD box helicase family
HB763_16065	COG3385	transposase activity
HB763_16080	COG3038	cytochrome b561
HB763_16090	COG2116	formate transmembrane transporter activity
HB763_16095	COG0583	DNA-binding transcription factor activity
HB763_16105	COG3593	DNA synthesis involved in DNA repair
HB763_16110	COG0737	Belongs to the 5'-nucleotidase family
HB763_16125	COG0646	methionine synthase
HB763_16125	COG1410	methionine synthase
HB763_16130	COG0076	glutamate decarboxylase activity
HB763_16135	COG0307	riboflavin synthase, alpha
HB763_16175	COG2267	carboxylic ester hydrolase activity
HB763_16180	COG2067	long-chain fatty acid transport protein
HB763_16190	COG0501	Belongs to the peptidase M48B family
HB763_16195	COG2050	protein possibly involved in aromatic compounds catabolism
HB763_16240	COG3300	MHYT domain
HB763_16240	COG5001	Diguanylate cyclase
HB763_16255	COG4181	ATPase activity
HB763_16260	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HB763_16270	COG1984	allophanate hydrolase subunit 2
HB763_16275	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HB763_16285	COG3447	MASE1 domain protein
HB763_16285	COG5002	protein histidine kinase activity
HB763_16285	COG5001	Diguanylate cyclase
HB763_16290	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HB763_16300	COG0583	DNA-binding transcription factor activity
HB763_16305	COG0045	succinate-CoA ligase (ADP-forming) activity
HB763_16305	COG1042	CoA-binding domain protein
HB763_16305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB763_16325	COG0023	Translation Initiation Factor
HB763_16410	COG2801	Transposase and inactivated derivatives
HB763_16420	COG3140	Belongs to the UPF0181 family
HB763_16445	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HB763_16450	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HB763_16470	COG2203	Gaf domain
HB763_16470	COG4251	negative regulation of phosphorylation
HB763_16470	COG5001	Diguanylate cyclase
HB763_16470	COG3706	GGDEF domain
HB763_16480	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HB763_16485	COG4149	molybdate abc transporter
HB763_16490	COG0725	ABC transporter, periplasmic molybdate-binding protein
HB763_16500	COG3111	PFAM Bacterial OB fold (BOF) protein
HB763_16525	COG0534	Mate efflux family protein
HB763_16530	COG0602	queuosine metabolic process
HB763_16535	COG1328	CTP reductase activity
HB763_16590	COG2197	response regulator
HB763_16595	COG3851	Histidine kinase
HB763_16600	COG2271	Major facilitator Superfamily
HB763_16605	COG1482	cell wall glycoprotein biosynthetic process
HB763_16640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HB763_16645	COG3118	belongs to the thioredoxin family
HB763_16670	COG0840	transmembrane signaling receptor activity
HB763_16675	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HB763_16745	COG0277	FAD linked oxidase domain protein
HB763_16750	COG0583	DNA-binding transcription factor activity
HB763_16765	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HB763_16780	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HB763_16790	COG1288	antiporter activity
HB763_16800	COG3040	lipid binding
HB763_16830	COG3469	chitinase activity
HB763_16840	COG0419	ATPase involved in DNA repair
HB763_16845	COG0420	3'-5' exonuclease activity
HB763_16875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HB763_16890	COG0840	transmembrane signaling receptor activity
HB763_16915	COG2755	lipolytic protein G-D-S-L family
HB763_16915	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HB763_16925	COG5642	Protein of unknown function (DUF2384)
HB763_16965	COG0671	phosphoesterase, PA-phosphatase related
HB763_16975	COG2962	Rard protein
HB763_16985	COG0835	chemotaxis
HB763_16985	COG0784	Response regulator, receiver
HB763_16990	COG0778	Nitroreductase
HB763_17010	COG3179	chitinase
HB763_17055	COG1522	sequence-specific DNA binding
HB763_17095	COG3335	DDE superfamily endonuclease
HB763_17125	COG3501	Rhs element vgr protein
HB763_17165	COG0739	heme binding
HB763_17180	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HB763_17210	COG3069	C4-dicarboxylate transmembrane transporter activity
HB763_17240	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HB763_17250	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HB763_17310	COG2205	protein histidine kinase activity
HB763_17310	COG2198	Histidine kinase
HB763_17310	COG0784	Response regulator, receiver
HB763_17315	COG1879	ABC-type sugar transport system periplasmic component
HB763_17325	COG0210	DNA helicase
HB763_17330	COG1289	transmembrane transporter activity
HB763_17355	COG0789	Transcriptional regulator
HB763_17360	COG4604	ABC transporter, ATP-binding protein
HB763_17365	COG4605	iron ion homeostasis
HB763_17370	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB763_17375	COG4607	ABC-type enterochelin transport system periplasmic component
HB763_17390	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HB763_17405	COG1609	Transcriptional regulator
HB763_17410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB763_17415	COG1879	ABC-type sugar transport system periplasmic component
HB763_17420	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB763_17425	COG1129	ABC transporter
HB763_17435	COG5001	Diguanylate cyclase
HB763_17530	COG0330	HflC and HflK could
HB763_17540	COG0517	IMP dehydrogenase activity
HB763_17540	COG4175	Glycine betaine
HB763_17545	COG4176	ABC-type proline glycine betaine transport system permease component
HB763_17580	COG2885	chlorophyll binding
HB763_17620	COG0455	bacterial-type flagellum organization
HB763_17630	COG4964	Belongs to the GSP D family
HB763_17650	COG0583	DNA-binding transcription factor activity
HB763_17695	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HB763_17695	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HB763_17710	COG4989	oxidoreductase activity
HB763_17740	COG0303	'Molybdopterin
HB763_17745	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HB763_17785	COG2897	thiosulfate sulfurtransferase activity
HB763_17805	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HB763_17810	COG0840	transmembrane signaling receptor activity
HB763_17820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB763_17825	COG2885	chlorophyll binding
HB763_17835	COG1612	heme a metabolic process
HB763_17860	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HB763_17875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HB763_17885	COG1280	lysine exporter protein (LysE YggA)
HB763_17905	COG0179	Fumarylacetoacetate (FAA) hydrolase
HB763_17920	COG0697	spore germination
HB763_17935	COG2814	Major facilitator Superfamily
HB763_17940	COG0583	DNA-binding transcription factor activity
HB763_17970	COG1120	ATPase activity
HB763_17975	COG5001	Diguanylate cyclase
HB763_17980	COG0739	heme binding
HB763_18000	COG3314	Sporulation integral membrane protein YlbJ
HB763_18015	COG0814	amino acid
HB763_18050	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HB763_18055	COG1120	ATPase activity
HB763_18080	COG0798	PFAM Bile acid sodium symporter
HB763_18095	COG1881	PFAM PEBP family protein
HB763_18105	COG0251	oxidation-reduction process
HB763_18110	COG2706	6-phosphogluconolactonase activity
HB763_18120	COG0800	Aldolase
HB763_18125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB763_18130	COG4145	pantothenate transmembrane transporter activity
HB763_18140	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HB763_18160	COG1131	(ABC) transporter
HB763_18165	COG0842	Transport permease protein
HB763_18200	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB763_18210	COG1280	lysine exporter protein (LysE YggA)
HB763_18215	COG0583	DNA-binding transcription factor activity
HB763_18225	COG0494	nUDIX hydrolase
HB763_18240	COG1858	cytochrome C peroxidase
HB763_18260	COG3335	DDE superfamily endonuclease
HB763_18275	COG1505	serine-type exopeptidase activity
HB763_18280	COG0488	(ABC) transporter
HB763_18290	COG0589	response to stress
HB763_18300	COG0584	glycerophosphoryl diester phosphodiesterase
HB763_18310	COG1175	transmembrane transport
HB763_18315	COG0395	ABC-type sugar transport system, permease component
HB763_18320	COG3842	ATPase activity
HB763_18345	COG0523	cobalamin synthesis protein
HB763_18355	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HB763_18365	COG4667	esterase of the alpha-beta hydrolase superfamily
HB763_18370	COG1741	Belongs to the pirin family
HB763_18375	COG1278	Cold shock
HB763_18390	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HB763_18400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB763_18410	COG1686	Belongs to the peptidase S11 family
HB763_18415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB763_18420	COG0625	glutathione transferase activity
HB763_18485	COG1764	response to oxidative stress
HB763_18490	COG2084	Dehydrogenase
HB763_18495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB763_18500	COG0823	Involved in the tonB-independent uptake of proteins
HB763_18520	COG0455	bacterial-type flagellum organization
HB763_18530	COG3385	transposase activity
HB763_18545	COG2801	Transposase and inactivated derivatives
HB763_18785	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HB763_18785	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HB763_18805	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_18830	COG3746	phosphate-selective porin O and P
HB763_18850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB763_18890	COG0513	Belongs to the DEAD box helicase family
HB763_18915	COG0583	DNA-binding transcription factor activity
HB763_18935	COG1902	pentaerythritol trinitrate reductase activity
HB763_18940	COG3853	Toxic anion resistance protein (TelA)
HB763_18950	COG2255	four-way junction helicase activity
HB763_18965	COG3122	Protein conserved in bacteria
HB763_18970	COG2321	neutral zinc metallopeptidase
HB763_18980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HB763_18985	COG1215	transferase activity, transferring glycosyl groups
HB763_18995	COG0583	DNA-binding transcription factor activity
HB763_19000	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HB763_19010	COG2207	Transcriptional regulator
HB763_19015	COG2807	transmembrane transport
HB763_19025	COG0574	Belongs to the PEP-utilizing enzyme family
HB763_19025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HB763_19045	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HB763_19055	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HB763_19090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB763_19120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB763_19170	COG4948	Mandelate Racemase Muconate Lactonizing
HB763_19210	COG4176	ABC-type proline glycine betaine transport system permease component
HB763_19215	COG3448	diguanylate cyclase activity
HB763_19215	COG4175	Glycine betaine
HB763_19230	COG0583	DNA-binding transcription factor activity
HB763_19240	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HB763_19290	COG2433	Pfam Transposase IS66
HB763_19310	COG3385	transposase activity
HB763_19345	COG1349	DNA-binding transcription factor activity
HB763_19350	COG0346	lactoylglutathione lyase activity
HB763_19355	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB763_19355	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB763_19365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB763_19385	COG1280	lysine exporter protein (LysE YggA)
HB763_19390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HB763_19405	COG0488	(ABC) transporter
HB763_19410	COG0435	Glutathione S-transferase
HB763_19415	COG0431	NADPH-dependent FMN reductase
HB763_19420	COG0583	DNA-binding transcription factor activity
HB763_19425	COG4628	conserved protein (DUF2132)
HB763_19430	COG0488	(ABC) transporter
HB763_19445	COG0346	lactoylglutathione lyase activity
HB763_19450	COG0384	phenazine biosynthesis protein PhzF
HB763_19480	COG2205	protein histidine kinase activity
HB763_19485	COG0745	RESPONSE REGULATOR receiver
HB763_19495	COG0454	-acetyltransferase
HB763_19505	COG2814	Major facilitator Superfamily
HB763_19515	COG2988	succinylglutamate desuccinylase activity
HB763_19525	COG0628	permease
HB763_19530	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HB763_19545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB763_19555	COG4628	conserved protein (DUF2132)
HB763_19560	COG0583	DNA-binding transcription factor activity
HB763_19570	COG1686	Belongs to the peptidase S11 family
HB763_19595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB763_19610	COG0415	Belongs to the DNA photolyase family
HB763_19615	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HB763_19625	COG4667	esterase of the alpha-beta hydrolase superfamily
HB763_19630	COG2095	MarC family integral membrane protein
HB763_19640	COG1596	polysaccharide export
HB763_19650	COG0489	protein tyrosine kinase activity
HB763_19650	COG3206	protein involved in exopolysaccharide biosynthesis
HB763_19685	COG1301	dicarboxylic acid transport
HB763_19690	COG3339	Conserved Protein
HB763_19705	COG2207	Transcriptional regulator
HB763_19720	COG0366	Alpha amylase catalytic
HB763_19725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HB763_19730	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HB763_19735	COG1640	4-alpha-glucanotransferase
HB763_19740	COG0058	SHG alpha-glucan phosphorylase activity
HB763_19760	COG1999	signal sequence binding
HB763_19770	COG1263	PTS System
HB763_19770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB763_19780	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HB763_19815	COG2356	endonuclease I
HB763_19870	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HB763_19870	COG0456	acetyltransferase
HB763_19940	COG3385	transposase activity
HB763_19955	COG4580	involved in the transport of maltose and maltodextrins
HB763_19975	COG2814	Major facilitator Superfamily
HB763_19985	COG0739	heme binding
HB763_20020	COG3121	Chaperone
HB763_20025	COG3188	usher protein
HB763_20045	COG3335	DDE superfamily endonuclease
HB763_20060	COG0612	Peptidase, M16
HB763_20065	COG0840	transmembrane signaling receptor activity
HB763_20085	COG1335	isochorismatase
HB763_20090	COG1136	(ABC) transporter
HB763_20095	COG0577	efflux transmembrane transporter activity
HB763_20145	COG1764	response to oxidative stress
HB763_20150	COG1846	Transcriptional regulator
HB763_20170	COG3634	alkyl hydroperoxide reductase activity
HB763_20180	COG2610	gluconate transmembrane transporter activity
HB763_20185	COG3622	Belongs to the hyi family
HB763_20190	COG0235	Class ii aldolase
HB763_20195	COG3395	kinase activity
HB763_20200	COG2084	Dehydrogenase
HB763_20205	COG1349	DNA-binding transcription factor activity
HB763_20230	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HB763_20240	COG1522	sequence-specific DNA binding
HB763_20245	COG0544	peptidyl-prolyl cis-trans isomerase activity
HB763_20260	COG2258	MOSC domain
HB763_20265	COG2153	protein acetylation
HB763_20275	COG3713	MltA-interacting MipA family protein
HB763_20280	COG0513	Belongs to the DEAD box helicase family
HB763_20305	COG1132	(ABC) transporter
HB763_20460	COG4166	transmembrane transport
HB763_20475	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HB763_20480	COG1263	PTS System
HB763_20480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB763_20485	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HB763_20510	COG1444	tRNA N-acetyltransferase activity
HB763_20535	COG4608	Belongs to the ABC transporter superfamily
HB763_20540	COG0444	Belongs to the ABC transporter superfamily
HB763_20550	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HB763_20550	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
HB763_20575	COG0772	Belongs to the SEDS family
HB763_20590	COG1136	(ABC) transporter
HB763_20610	COG3275	phosphorelay sensor kinase activity
HB763_20615	COG3279	Response regulator of the LytR AlgR family
HB763_20625	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HB763_20645	COG0786	glutamate:sodium symporter activity
HB763_20650	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_20715	COG2897	thiosulfate sulfurtransferase activity
HB763_20725	COG1131	(ABC) transporter
HB763_20730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB763_20735	COG0786	glutamate:sodium symporter activity
HB763_20765	COG0561	phosphatase activity
HB763_20770	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HB763_20775	COG3623	hexulose-6-phosphate isomerase
HB763_20810	COG2259	Doxx family
HB763_20825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HB763_20895	COG1609	Transcriptional regulator
HB763_20910	COG0395	ABC-type sugar transport system, permease component
HB763_20915	COG2723	6-phospho-beta-galactosidase activity
HB763_20920	COG3842	ATPase activity
HB763_20925	COG1609	Transcriptional regulator
HB763_20935	COG0564	pseudouridine synthase activity
HB763_20940	COG0561	phosphatase activity
HB763_20960	COG3152	Membrane
HB763_20980	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HB763_20995	COG0583	DNA-binding transcription factor activity
HB763_21045	COG2076	Multidrug Resistance protein
HB763_21055	COG1357	PFAM Pentapeptide repeats (8 copies)
HB763_21060	COG3047	cAMP biosynthetic process
HB763_21150	COG0668	transmembrane transport
HB763_21195	COG3835	regulator
HB763_21200	COG1929	Belongs to the glycerate kinase type-1 family
HB763_21205	COG0477	Major facilitator Superfamily
HB763_21225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB763_21230	COG0697	spore germination
HB763_21275	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_21290	COG0671	phosphoesterase, PA-phosphatase related
HB763_21305	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HB763_21310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB763_21315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB763_21320	COG1116	anion transmembrane transporter activity
HB763_21325	COG0351	phosphomethylpyrimidine kinase
HB763_21330	COG0312	modulator of DNA gyrase
HB763_21335	COG0312	modulator of DNA gyrase
HB763_21395	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HB763_21405	COG0584	glycerophosphoryl diester phosphodiesterase
HB763_21410	COG0745	RESPONSE REGULATOR receiver
HB763_21415	COG2205	protein histidine kinase activity
HB763_21430	COG0811	peptide transport
HB763_21435	COG0811	peptide transport
HB763_21440	COG0848	biopolymer transport protein
HB763_21485	COG0803	Belongs to the bacterial solute-binding protein 9 family
HB763_21490	COG1121	(ABC) transporter
HB763_21495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB763_21510	COG1770	oligopeptidase
HB763_21515	COG2814	Major facilitator Superfamily
HB763_21520	COG0010	Belongs to the arginase family
HB763_21525	COG1166	arginine decarboxylase activity
HB763_21535	COG4067	protein conserved in archaea
HB763_21535	COG0189	ligase activity
HB763_21540	COG0189	ligase activity
HB763_21560	COG0583	DNA-binding transcription factor activity
HB763_21600	COG1114	Component of the transport system for branched-chain amino acids
HB763_21615	COG0579	oxidoreductase
HB763_21620	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HB763_21635	COG3033	Beta-eliminating lyase
HB763_21650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB763_21655	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HB763_21690	COG3706	GGDEF domain
HB763_21695	COG0415	Belongs to the DNA photolyase family
HB763_21700	COG3046	protein related to deoxyribodipyrimidine photolyase
HB763_21715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB763_21715	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB763_21720	COG1765	OsmC-like protein
HB763_21760	COG1011	Hydrolase
HB763_21785	COG3240	lipase activity
HB763_21805	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HB763_21815	COG1840	ABC-type Fe3 transport system, periplasmic component
HB763_21820	COG3842	ATPase activity
HB763_21845	COG2990	Protein conserved in bacteria
HB763_21855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB763_21860	COG2866	Carboxypeptidase
HB763_21870	COG0583	DNA-binding transcription factor activity
HB763_21895	COG3104	oligopeptide transport
HB763_21900	COG1760	l-serine dehydratase
HB763_21925	COG0741	lytic transglycosylase activity
HB763_21925	COG1388	LysM domain
HB763_21945	COG1815	bacterial-type flagellum-dependent cell motility
HB763_21950	COG1558	bacterial-type flagellum-dependent cell motility
HB763_21955	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HB763_21960	COG1749	Flagellar hook protein flgE
HB763_21965	COG4787	bacterial-type flagellum-dependent cell motility
HB763_21970	COG4786	Flagellar basal body rod
HB763_21975	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HB763_21980	COG1706	bacterial-type flagellum-dependent cell motility
HB763_21990	COG1256	bacterial-type flagellum assembly
HB763_21990	COG4786	Flagellar basal body rod
HB763_21995	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB763_22060	COG0384	phenazine biosynthesis protein PhzF
HB763_22070	COG1360	Flagellar Motor Protein
HB763_22075	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HB763_22080	COG1191	sigma factor activity
HB763_22085	COG1580	Controls the rotational direction of flagella during chemotaxis
HB763_22100	COG1516	flagellar protein fliS
HB763_22105	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HB763_22115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB763_22140	COG1987	bacterial-type flagellum assembly
HB763_22240	COG0346	lactoylglutathione lyase activity
HB763_22265	COG0745	RESPONSE REGULATOR receiver
HB763_22290	COG0156	8-amino-7-oxononanoate synthase activity
HB763_22295	COG1063	alcohol dehydrogenase
HB763_22335	COG1063	alcohol dehydrogenase
HB763_22360	COG2199	diguanylate cyclase activity
HB763_22360	COG2203	Gaf domain
HB763_22365	COG2223	nitrite transmembrane transporter activity
HB763_22370	COG1063	alcohol dehydrogenase
HB763_22380	COG0668	transmembrane transport
HB763_22390	COG1304	FMN binding
HB763_22400	COG1620	l-lactate permease
HB763_22405	COG0583	DNA-binding transcription factor activity
HB763_22410	COG1505	serine-type exopeptidase activity
HB763_22415	COG4172	Belongs to the ABC transporter superfamily
HB763_22425	COG1067	ATP-dependent peptidase activity
HB763_22435	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HB763_22455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB763_22475	COG1122	ATPase activity
HB763_22485	COG1566	PFAM secretion protein HlyD family protein
HB763_22500	COG3706	GGDEF domain
HB763_22515	COG0813	purine-nucleoside phosphorylase activity
HB763_22520	COG3272	Protein of unknown function (DUF1722)
HB763_22525	COG0789	Transcriptional regulator
HB763_22530	COG0415	Belongs to the DNA photolyase family
HB763_22535	COG1388	LysM domain
HB763_22535	COG1376	ErfK ybiS ycfS ynhG family protein
HB763_22545	COG0513	Belongs to the DEAD box helicase family
HB763_22555	COG1770	oligopeptidase
HB763_22560	COG4771	TonB-dependent receptor
HB763_22580	COG0840	transmembrane signaling receptor activity
HB763_22590	COG0573	inorganic phosphate transmembrane transporter activity
HB763_22595	COG0581	inorganic phosphate transmembrane transporter activity
HB763_22600	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HB763_22615	COG2304	oxidoreductase activity
HB763_22635	COG0714	Associated with various cellular activities
HB763_22640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB763_22655	COG2197	response regulator
HB763_22685	COG3852	Histidine kinase
HB763_22690	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_22720	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
HB763_22740	COG1252	NADH dehydrogenase
HB763_22745	COG1301	dicarboxylic acid transport
HB763_22750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB763_22775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB763_22775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB763_22775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB763_22780	COG2207	Transcriptional regulator
HB763_22790	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB763_22795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB763_22805	COG2084	Dehydrogenase
HB763_22810	COG0753	catalase activity
HB763_22820	COG2130	NADP-dependent
HB763_22825	COG1309	transcriptional regulator
HB763_22870	COG0489	protein tyrosine kinase activity
HB763_22870	COG3206	protein involved in exopolysaccharide biosynthesis
HB763_22885	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HB763_22890	COG3842	ATPase activity
HB763_22900	COG1175	transmembrane transport
HB763_22905	COG3833	ABC-type maltose transport systems, permease component
HB763_22935	COG2354	Protein conserved in bacteria
HB763_22950	COG0633	Ferredoxin
HB763_22950	COG3217	Mosc domain protein beta barrel domain protein
HB763_22950	COG0633	Ferredoxin
HB763_22950	COG3217	Mosc domain protein beta barrel domain protein
HB763_22960	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HB763_23000	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HB763_23005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB763_23015	COG0848	biopolymer transport protein
HB763_23020	COG0811	peptide transport
HB763_23025	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HB763_23035	COG3721	Heme iron utilization protein
HB763_23040	COG0748	coenzyme F420 binding
HB763_23050	COG0784	Response regulator, receiver
HB763_23050	COG0835	chemotaxis
HB763_23055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB763_23060	COG0366	Alpha amylase catalytic
HB763_23095	COG0583	DNA-binding transcription factor activity
HB763_23115	COG0583	DNA-binding transcription factor activity
HB763_23135	COG2814	Major facilitator Superfamily
HB763_23145	COG4977	sequence-specific DNA binding
HB763_23150	COG0673	inositol 2-dehydrogenase activity
HB763_23155	COG2194	sulfuric ester hydrolase activity
HB763_23160	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HB763_23170	COG2205	protein histidine kinase activity
HB763_23175	COG0745	RESPONSE REGULATOR receiver
HB763_23180	COG4221	oxidoreductase activity
HB763_23195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB763_23215	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HB763_23225	COG2814	Major facilitator Superfamily
HB763_23240	COG1418	mRNA catabolic process
HB763_23255	COG0402	S-adenosylhomocysteine deaminase activity
HB763_23260	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HB763_23265	COG2239	Acts as a magnesium transporter
HB763_23270	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HB763_23275	COG1566	PFAM secretion protein HlyD family protein
HB763_23300	COG0745	RESPONSE REGULATOR receiver
HB763_23305	COG2205	protein histidine kinase activity
HB763_23315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB763_23320	COG0531	amino acid
HB763_23325	COG1522	sequence-specific DNA binding
HB763_23335	COG0583	DNA-binding transcription factor activity
HB763_23365	COG0673	inositol 2-dehydrogenase activity
HB763_23445	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB763_23450	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB763_23460	COG1280	lysine exporter protein (LysE YggA)
HB763_23470	COG0183	Belongs to the thiolase family
HB763_23490	COG3005	denitrification pathway
HB763_23510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB763_23515	COG3850	Histidine kinase
HB763_23520	COG2197	response regulator
HB763_23535	COG2195	Cleaves the N-terminal amino acid of tripeptides
HB763_23560	COG0840	transmembrane signaling receptor activity
HB763_23570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB763_23575	COG0545	Peptidyl-prolyl cis-trans isomerase
HB763_23605	COG1278	Cold shock
HB763_23610	COG3036	rescue of stalled ribosome
HB763_23620	COG2199	diguanylate cyclase activity
HB763_23635	COG0577	efflux transmembrane transporter activity
HB763_23635	COG1136	(ABC) transporter
HB763_23640	COG0577	efflux transmembrane transporter activity
HB763_23640	COG1136	(ABC) transporter
HB763_23650	COG0840	transmembrane signaling receptor activity
HB763_23655	COG0783	Belongs to the Dps family
HB763_23665	COG1619	proteins homologs of microcin C7 resistance protein MccF
HB763_23670	COG2133	pyrroloquinoline quinone binding
HB763_23675	COG1454	alcohol dehydrogenase
HB763_23680	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HB763_23705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB763_23715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HB763_23720	COG3186	Phenylalanine-4-hydroxylase
HB763_23745	COG3530	Putative quorum-sensing-regulated virulence factor
HB763_23770	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HB763_23775	COG1845	cytochrome c oxidase, subunit III
HB763_23780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HB763_23785	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HB763_23795	COG0454	-acetyltransferase
HB763_23830	COG0523	cobalamin synthesis protein
HB763_23835	COG5002	protein histidine kinase activity
HB763_23835	COG5001	Diguanylate cyclase
HB763_23835	COG3447	MASE1 domain protein
HB763_23840	COG0513	Belongs to the DEAD box helicase family
HB763_23860	COG2200	EAL domain
HB763_23865	COG1119	ATPase activity
HB763_23880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HB763_23895	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
HB763_23900	COG0513	Belongs to the DEAD box helicase family
HB763_23910	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HB763_23925	COG3278	Belongs to the heme-copper respiratory oxidase family
HB763_23965	COG1024	Enoyl-CoA hydratase
HB763_23970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HB763_23975	COG1960	acyl-CoA dehydrogenase activity
HB763_23985	COG0183	Belongs to the thiolase family
HB763_24000	COG1024	Enoyl-CoA hydratase
HB763_24005	COG1024	Enoyl-CoA hydratase
HB763_24015	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_24020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HB763_24025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HB763_24030	COG1845	cytochrome c oxidase, subunit III
HB763_24035	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HB763_24045	COG1902	pentaerythritol trinitrate reductase activity
HB763_24045	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB763_24060	COG1012	belongs to the aldehyde dehydrogenase family
HB763_24070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB763_24105	COG1126	abc transporter atp-binding protein
HB763_24110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB763_24115	COG4215	(ABC) transporter
HB763_24120	COG4160	amino acid transport
HB763_24145	COG3385	transposase activity
HB763_24160	COG5002	protein histidine kinase activity
HB763_24165	COG2200	EAL domain
HB763_24210	COG0443	Heat shock 70 kDa protein
HB763_24235	COG1785	Belongs to the alkaline phosphatase family
HB763_24275	COG0814	amino acid
HB763_24285	COG0243	molybdopterin cofactor binding
HB763_24290	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HB763_24290	COG1648	precorrin-2 dehydrogenase activity
HB763_24310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB763_24310	COG1116	anion transmembrane transporter activity
HB763_24315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB763_24320	COG1116	anion transmembrane transporter activity
HB763_24325	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HB763_24325	COG2146	nitrite reductase [NAD(P)H] activity
HB763_24375	COG0739	heme binding
HB763_24385	COG3038	cytochrome b561
HB763_24495	COG2814	Major facilitator Superfamily
HB763_24510	COG2816	NAD+ diphosphatase activity
HB763_24515	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HB763_24540	COG1132	(ABC) transporter
HB763_24555	COG3335	DDE superfamily endonuclease
HB763_24590	COG0583	DNA-binding transcription factor activity
HB763_24620	COG4772	TonB-dependent receptor
HB763_24625	COG1120	ATPase activity
HB763_24630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB763_24635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB763_24640	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HB763_24665	COG3335	DDE superfamily endonuclease
HB763_24690	COG3005	denitrification pathway
HB763_24800	COG0456	acetyltransferase
HB763_24825	COG0625	glutathione transferase activity
HB763_24850	COG2801	Transposase and inactivated derivatives
HB763_24865	COG0456	acetyltransferase
HB763_24910	COG2801	Transposase and inactivated derivatives
HB763_24965	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HB763_24975	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HB763_24990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB763_25005	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HB763_25005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB763_25005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB763_25010	COG1105	Belongs to the carbohydrate kinase PfkB family
HB763_25015	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB763_25015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB763_25020	COG1609	Transcriptional regulator
HB763_25035	COG2200	EAL domain
HB763_25035	COG2199	diguanylate cyclase activity
HB763_25035	COG2203	Gaf domain
HB763_25040	COG0765	amino acid transport
HB763_25045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB763_25050	COG0765	amino acid transport
HB763_25055	COG1126	abc transporter atp-binding protein
HB763_25065	COG1979	alcohol dehydrogenase
HB763_25070	COG2207	Transcriptional regulator
HB763_25080	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HB763_25145	COG1192	Involved in chromosome partitioning