locus-tag	class	description
HB762_00005	COG0508	dehydrogenase complex catalyzes the overall conversion of
HB762_00010	COG4137	Cytochrome C assembly protein
HB762_00015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HB762_00020	COG0228	four-way junction DNA binding
HB762_00040	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HB762_00045	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HB762_00050	COG0237	dephospho-CoA kinase activity
HB762_00060	COG1459	type II secretion system
HB762_00065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB762_00085	COG2186	Transcriptional regulator
HB762_00090	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HB762_00095	COG0508	dehydrogenase complex catalyzes the overall conversion of
HB762_00100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB762_00115	COG0288	reversible hydration of carbon dioxide
HB762_00120	COG0659	secondary active sulfate transmembrane transporter activity
HB762_00125	COG1131	(ABC) transporter
HB762_00130	COG0842	Transport permease protein
HB762_00135	COG1560	Kdo2-lipid A biosynthetic process
HB762_00150	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HB762_00160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HB762_00175	COG1643	Atp-dependent helicase
HB762_00180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HB762_00185	COG1752	Esterase of the alpha-beta hydrolase superfamily
HB762_00190	COG1049	propionate catabolic process, 2-methylcitrate cycle
HB762_00205	COG0004	ammonium transporteR
HB762_00210	COG1840	ABC-type Fe3 transport system, periplasmic component
HB762_00220	COG3842	ATPase activity
HB762_00225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HB762_00240	COG2971	BadF BadG BcrA BcrD
HB762_00250	COG4608	Belongs to the ABC transporter superfamily
HB762_00255	COG0444	Belongs to the ABC transporter superfamily
HB762_00260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB762_00270	COG0747	negative chemotaxis
HB762_00275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB762_00275	COG2198	Histidine kinase
HB762_00275	COG2205	protein histidine kinase activity
HB762_00275	COG0784	Response regulator, receiver
HB762_00285	COG0628	permease
HB762_00305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB762_00310	COG0739	heme binding
HB762_00315	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HB762_00330	COG2027	D-alanyl-D-alanine carboxypeptidase
HB762_00335	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HB762_00340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB762_00345	COG1534	Rna-binding protein
HB762_00355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HB762_00360	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HB762_00370	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HB762_00390	COG0195	Participates in both transcription termination and antitermination
HB762_00410	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HB762_00455	COG0534	Mate efflux family protein
HB762_00460	COG0826	peptidase U32
HB762_00465	COG0826	peptidase U32
HB762_00475	COG3154	lipid carrier protein
HB762_00480	COG3153	acetyltransferase
HB762_00510	COG0084	hydrolase, TatD family'
HB762_00515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB762_00525	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HB762_00535	COG0813	purine-nucleoside phosphorylase activity
HB762_00545	COG0560	Phosphoserine phosphatase
HB762_00555	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HB762_00560	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HB762_00590	COG1022	Amp-dependent synthetase and ligase
HB762_00605	COG0583	DNA-binding transcription factor activity
HB762_00610	COG1609	Transcriptional regulator
HB762_00615	COG0768	penicillin binding
HB762_00620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HB762_00635	COG0741	lytic transglycosylase activity
HB762_00650	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HB762_00655	COG1349	DNA-binding transcription factor activity
HB762_00665	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HB762_00670	COG2271	Major facilitator Superfamily
HB762_00675	COG0584	glycerophosphoryl diester phosphodiesterase
HB762_00680	COG2171	N-acyltransferase activity
HB762_00695	COG3141	response to X-ray
HB762_00720	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HB762_00725	COG1074	ATP-dependent DNA helicase activity
HB762_00730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HB762_00740	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HB762_00740	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HB762_00750	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HB762_00755	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HB762_00760	COG2166	iron-sulfur cluster assembly
HB762_00765	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HB762_00770	COG0693	protein deglycase activity
HB762_00775	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HB762_00780	COG3248	Nucleoside-binding outer membrane protein
HB762_00795	COG1595	DNA-templated transcription, initiation
HB762_00825	COG0271	Belongs to the BolA IbaG family
HB762_00830	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HB762_00835	COG1805	sodium ion transport
HB762_00845	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HB762_00850	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HB762_00860	COG1477	protein flavinylation
HB762_00875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HB762_00880	COG0514	ATP-dependent DNA helicase (RecQ)
HB762_00885	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB762_00900	COG0733	neurotransmitter:sodium symporter activity
HB762_00925	COG1720	tRNA m6t6A37 methyltransferase activity
HB762_00940	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HB762_00970	COG3098	single-species biofilm formation
HB762_00975	COG0564	pseudouridine synthase activity
HB762_00990	COG0024	Methionine aminopeptidase
HB762_01015	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HB762_01020	COG0575	Belongs to the CDS family
HB762_01030	COG0750	zinc metalloprotease
HB762_01040	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HB762_01045	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HB762_01070	COG0587	DNA-directed DNA polymerase activity
HB762_01090	COG0347	Belongs to the P(II) protein family
HB762_01105	COG1388	LysM domain
HB762_01105	COG0741	lytic transglycosylase activity
HB762_01115	COG2226	methyltransferase
HB762_01125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HB762_01150	COG1960	acyl-CoA dehydrogenase activity
HB762_01155	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HB762_01160	COG0121	glutamine amidotransferase
HB762_01165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HB762_01170	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HB762_01175	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HB762_01180	COG2233	PERMEase
HB762_01200	COG1393	Belongs to the ArsC family
HB762_01205	COG4783	chaperone-mediated protein folding
HB762_01220	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HB762_01225	COG2716	regulation of RNA biosynthetic process
HB762_01230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HB762_01235	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HB762_01255	COG1393	Belongs to the ArsC family
HB762_01280	COG2837	iron assimilation
HB762_01300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB762_01305	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB762_01310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB762_01315	COG1334	flagellar protein FlaG
HB762_01320	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HB762_01330	COG1516	flagellar protein fliS
HB762_01350	COG1677	Flagellar hook-basal body complex protein FliE
HB762_01360	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HB762_01415	COG1987	bacterial-type flagellum assembly
HB762_01420	COG1684	flagellar biosynthetic protein fliR
HB762_01455	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HB762_01460	COG0784	Response regulator, receiver
HB762_01460	COG2198	Histidine kinase
HB762_01460	COG0643	Histidine kinase
HB762_01465	COG2201	protein-glutamate methylesterase activity
HB762_01470	COG1192	Involved in chromosome partitioning
HB762_01480	COG0835	chemotaxis
HB762_01490	COG4133	protoheme IX ABC transporter activity
HB762_01495	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HB762_01500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HB762_01515	COG1138	Cytochrome C-type biogenesis protein
HB762_01520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HB762_01530	COG3088	subunit of a heme lyase
HB762_01530	COG4235	cytochrome complex assembly
HB762_01535	COG2853	Lipoprotein
HB762_01540	COG2067	long-chain fatty acid transport protein
HB762_01545	COG2067	long-chain fatty acid transport protein
HB762_01560	COG0183	Belongs to the thiolase family
HB762_01575	COG2062	phosphohistidine phosphatase, SixA
HB762_01585	COG2890	protein-(glutamine-N5) methyltransferase activity
HB762_01600	COG2860	membrane
HB762_01605	COG3101	peptidyl-lysine hydroxylation
HB762_01625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HB762_01630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HB762_01635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HB762_01655	COG0285	dihydrofolate synthase activity
HB762_01660	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HB762_01665	COG1286	toxin biosynthetic process
HB762_01670	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HB762_01675	COG0583	DNA-binding transcription factor activity
HB762_01680	COG0745	RESPONSE REGULATOR receiver
HB762_01685	COG2832	Protein of unknown function (DUF454)
HB762_01695	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HB762_01705	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HB762_01710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HB762_01715	COG0814	amino acid
HB762_01720	COG0251	oxidation-reduction process
HB762_01730	COG2964	Protein conserved in bacteria
HB762_01740	COG2983	Belongs to the UPF0260 family
HB762_01745	COG2261	transglycosylase associated protein
HB762_01750	COG2985	domain, Protein
HB762_01755	COG0076	glutamate decarboxylase activity
HB762_01760	COG0668	transmembrane transport
HB762_01770	COG0346	lactoylglutathione lyase activity
HB762_01780	COG1785	Belongs to the alkaline phosphatase family
HB762_01800	COG2226	methyltransferase
HB762_01820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HB762_01825	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB762_01835	COG3139	Protein of unknown function (DUF1315)
HB762_01840	COG0252	asparaginase activity
HB762_01845	COG0616	signal peptide processing
HB762_01850	COG1902	pentaerythritol trinitrate reductase activity
HB762_01850	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB762_01855	COG0778	Nitroreductase
HB762_01860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HB762_01875	COG0123	including yeast histone deacetylase and acetoin utilization protein
HB762_01885	COG4269	membrane
HB762_01900	COG3083	sulfuric ester hydrolase activity
HB762_01925	COG1757	Na H antiporter
HB762_01930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HB762_01935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB762_01940	COG2095	MarC family integral membrane protein
HB762_01945	COG1012	belongs to the aldehyde dehydrogenase family
HB762_01945	COG1454	alcohol dehydrogenase
HB762_01950	COG1028	Short-chain dehydrogenase reductase Sdr
HB762_01965	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HB762_01980	COG2056	Na+-H+ antiporter family
HB762_01990	COG2885	chlorophyll binding
HB762_02000	COG0346	lactoylglutathione lyase activity
HB762_02005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HB762_02010	COG4660	Part of a membrane complex involved in electron transport
HB762_02015	COG4659	FMN binding
HB762_02020	COG4658	electron transport chain
HB762_02025	COG4656	Part of a membrane complex involved in electron transport
HB762_02035	COG4657	Part of a membrane complex involved in electron transport
HB762_02095	COG0556	nucleotide-excision repair
HB762_02110	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HB762_02115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HB762_02120	COG0521	Mo-molybdopterin cofactor biosynthetic process
HB762_02130	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HB762_02135	COG0314	molybdopterin synthase activity
HB762_02145	COG0601	transmembrane transport
HB762_02150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB762_02155	COG0444	Belongs to the ABC transporter superfamily
HB762_02165	COG0435	Glutathione S-transferase
HB762_02170	COG0280	phosphate acetyltransferase
HB762_02170	COG0857	belongs to the CobB CobQ family
HB762_02190	COG4120	Belongs to the binding-protein-dependent transport system permease family
HB762_02195	COG1122	ATPase activity
HB762_02200	COG0366	Alpha amylase catalytic
HB762_02210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HB762_02215	COG0653	protein targeting
HB762_02220	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HB762_02230	COG2186	Transcriptional regulator
HB762_02260	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HB762_02265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HB762_02270	COG0659	secondary active sulfate transmembrane transporter activity
HB762_02275	COG1530	ribonuclease E activity
HB762_02280	COG0564	pseudouridine synthase activity
HB762_02285	COG0424	maF-like protein
HB762_02290	COG1399	metal-binding, possibly nucleic acid-binding protein
HB762_02305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HB762_02335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HB762_02350	COG0084	hydrolase, TatD family'
HB762_02355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB762_02355	COG1263	PTS System
HB762_02370	COG0733	neurotransmitter:sodium symporter activity
HB762_02385	COG4667	esterase of the alpha-beta hydrolase superfamily
HB762_02415	COG2272	Belongs to the type-B carboxylesterase lipase family
HB762_02425	COG3710	Transcriptional regulator
HB762_02440	COG1940	carbohydrate kinase activity
HB762_02445	COG0784	Response regulator, receiver
HB762_02445	COG0835	chemotaxis
HB762_02465	COG1028	Short-chain dehydrogenase reductase Sdr
HB762_02470	COG0616	signal peptide processing
HB762_02480	COG0539	negative regulation of cytoplasmic translation
HB762_02490	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HB762_02495	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HB762_02505	COG4166	transmembrane transport
HB762_02520	COG3009	Protein conserved in bacteria
HB762_02525	COG3008	intermembrane lipid transfer
HB762_02525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HB762_02530	COG2995	paraquat-inducible protein a
HB762_02545	COG4232	protein-disulfide reductase activity
HB762_02550	COG3118	belongs to the thioredoxin family
HB762_02560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HB762_02570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB762_02585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB762_02595	COG0577	efflux transmembrane transporter activity
HB762_02600	COG0577	efflux transmembrane transporter activity
HB762_02600	COG1136	(ABC) transporter
HB762_02605	COG0577	efflux transmembrane transporter activity
HB762_02605	COG1136	(ABC) transporter
HB762_02620	COG2176	DNA-directed DNA polymerase activity
HB762_02655	COG1217	gtp-binding protein TYPA
HB762_02665	COG2207	Transcriptional regulator
HB762_02665	COG3708	Transcriptional regulator
HB762_02675	COG3615	Tellurite resistance protein tehB
HB762_02735	COG3850	Histidine kinase
HB762_02735	COG5002	protein histidine kinase activity
HB762_02740	COG0745	RESPONSE REGULATOR receiver
HB762_02745	COG0463	Glycosyl transferase, family 2
HB762_02750	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HB762_02760	COG0840	transmembrane signaling receptor activity
HB762_02765	COG2175	clavaminate synthase activity
HB762_02865	COG1032	radical SAM domain protein
HB762_02870	COG1716	ATPase activity
HB762_02870	COG5001	Diguanylate cyclase
HB762_02900	COG2350	Protein conserved in bacteria
HB762_02925	COG1301	dicarboxylic acid transport
HB762_02930	COG0159	tryptophan synthase activity
HB762_02940	COG0135	phosphoribosylanthranilate isomerase activity
HB762_02940	COG0134	indole-3-glycerol-phosphate synthase activity
HB762_02950	COG0512	Glutamine amidotransferase of anthranilate synthase
HB762_02955	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HB762_02965	COG0613	PHP domain protein
HB762_02970	COG0009	L-threonylcarbamoyladenylate synthase
HB762_02980	COG1187	pseudouridine synthase activity
HB762_03000	COG0417	DNA replication proofreading
HB762_03005	COG2197	response regulator
HB762_03010	COG0322	excinuclease ABC activity
HB762_03050	COG0019	diaminopimelate decarboxylase activity
HB762_03065	COG1058	Belongs to the CinA family
HB762_03065	COG1546	Belongs to the CinA family
HB762_03075	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB762_03080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB762_03120	COG3088	subunit of a heme lyase
HB762_03120	COG4235	cytochrome complex assembly
HB762_03155	COG2989	Protein conserved in bacteria
HB762_03160	COG3108	Peptidase M15
HB762_03165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HB762_03180	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HB762_03205	COG1846	Transcriptional regulator
HB762_03210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB762_03215	COG0840	transmembrane signaling receptor activity
HB762_03235	COG1448	Aminotransferase
HB762_03255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB762_03270	COG0017	Asparaginyl-tRNA synthetase
HB762_03280	COG0720	synthase
HB762_03285	COG2197	response regulator
HB762_03300	COG3300	MHYT domain
HB762_03300	COG5001	Diguanylate cyclase
HB762_03305	COG1760	l-serine dehydratase
HB762_03310	COG0814	amino acid
HB762_03325	COG2205	protein histidine kinase activity
HB762_03325	COG0784	Response regulator, receiver
HB762_03330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HB762_03345	COG3106	COG3106 Predicted ATPase
HB762_03360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB762_03425	COG1335	isochorismatase
HB762_03475	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HB762_03475	COG0517	IMP dehydrogenase activity
HB762_03630	COG1335	isochorismatase
HB762_03730	COG3152	Membrane
HB762_03795	COG2801	Transposase and inactivated derivatives
HB762_03855	COG3340	Belongs to the peptidase S51 family
HB762_03880	COG0456	acetyltransferase
HB762_03905	COG1328	CTP reductase activity
HB762_03910	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HB762_03920	COG0861	Integral membrane protein TerC family
HB762_03930	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HB762_03935	COG4221	oxidoreductase activity
HB762_03945	COG0814	amino acid
HB762_03965	COG1132	(ABC) transporter
HB762_03970	COG1132	(ABC) transporter
HB762_03975	COG2165	general secretion pathway protein
HB762_03990	COG0443	Heat shock 70 kDa protein
HB762_03995	COG0443	Heat shock 70 kDa protein
HB762_04005	COG3706	GGDEF domain
HB762_04035	COG3227	Zinc metalloprotease (Elastase)
HB762_04055	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HB762_04065	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HB762_04105	COG1643	Atp-dependent helicase
HB762_04130	COG3063	Type IV pilus biogenesis stability protein PilW
HB762_04170	COG1280	lysine exporter protein (LysE YggA)
HB762_04195	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HB762_04215	COG1280	lysine exporter protein (LysE YggA)
HB762_04225	COG1280	lysine exporter protein (LysE YggA)
HB762_04255	COG1115	amino acid carrier protein
HB762_04280	COG1368	sulfuric ester hydrolase activity
HB762_04295	COG0215	cysteine-tRNA ligase activity
HB762_04305	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HB762_04315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB762_04330	COG1858	cytochrome C peroxidase
HB762_04335	COG1404	Belongs to the peptidase S8 family
HB762_04545	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HB762_04550	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HB762_04560	COG1280	lysine exporter protein (LysE YggA)
HB762_04595	COG0454	-acetyltransferase
HB762_04770	COG0318	PFAM AMP-dependent synthetase and ligase
HB762_04785	COG0668	transmembrane transport
HB762_04790	COG3247	response to pH
HB762_04805	COG1846	Transcriptional regulator
HB762_04825	COG2205	protein histidine kinase activity
HB762_04825	COG0784	Response regulator, receiver
HB762_04850	COG2205	protein histidine kinase activity
HB762_04850	COG3437	response regulator, receiver
HB762_04850	COG3850	Histidine kinase
HB762_04850	COG4999	Histidine kinase
HB762_04855	COG5001	Diguanylate cyclase
HB762_04855	COG3300	MHYT domain
HB762_04880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HB762_04885	COG1215	transferase activity, transferring glycosyl groups
HB762_04890	COG0438	transferase activity, transferring glycosyl groups
HB762_04920	COG0438	transferase activity, transferring glycosyl groups
HB762_04925	COG0438	transferase activity, transferring glycosyl groups
HB762_04930	COG2204	response regulator
HB762_04950	COG2885	chlorophyll binding
HB762_04960	COG1793	dna ligase
HB762_04970	COG0534	Mate efflux family protein
HB762_04975	COG0307	riboflavin synthase, alpha
HB762_04985	COG3001	Fructosamine kinase
HB762_04990	COG2201	protein-glutamate methylesterase activity
HB762_04995	COG3706	GGDEF domain
HB762_05005	COG0791	NLP P60 protein
HB762_05010	COG0840	transmembrane signaling receptor activity
HB762_05055	COG3148	PFAM DTW domain containing protein
HB762_05060	COG1940	carbohydrate kinase activity
HB762_05070	COG0303	'Molybdopterin
HB762_05080	COG3842	ATPase activity
HB762_05085	COG4662	Binding-protein-dependent transport system inner membrane component
HB762_05095	COG2204	response regulator
HB762_05100	COG4191	Histidine kinase
HB762_05115	COG0488	(ABC) transporter
HB762_05120	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HB762_05140	COG3381	protein complex oligomerization
HB762_05150	COG0243	molybdopterin cofactor binding
HB762_05150	COG3383	formate dehydrogenase (NAD+) activity
HB762_05155	COG0437	4 iron, 4 sulfur cluster binding
HB762_05170	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HB762_05175	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HB762_05185	COG1177	transmembrane transport
HB762_05195	COG3842	ATPase activity
HB762_05220	COG0589	response to stress
HB762_05225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB762_05240	COG2217	Heavy metal translocating P-type atpase
HB762_05250	COG2010	Cytochrome c
HB762_05265	COG3278	Belongs to the heme-copper respiratory oxidase family
HB762_05280	COG0784	Response regulator, receiver
HB762_05280	COG2205	protein histidine kinase activity
HB762_05385	COG1067	ATP-dependent peptidase activity
HB762_05405	COG0488	(ABC) transporter
HB762_05430	COG2902	Dehydrogenase
HB762_05440	COG0308	aminopeptidase N
HB762_05455	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HB762_05460	COG1956	GAF domain-containing protein
HB762_05465	COG1132	(ABC) transporter
HB762_05470	COG2995	paraquat-inducible protein a
HB762_05475	COG3008	intermembrane lipid transfer
HB762_05500	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB762_05515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB762_05520	COG4597	amino acid ABC transporter
HB762_05525	COG0765	amino acid transport
HB762_05530	COG1126	abc transporter atp-binding protein
HB762_05535	COG0670	Belongs to the BI1 family
HB762_05540	COG2920	part of a sulfur-relay system
HB762_05545	COG1254	Belongs to the acylphosphatase family
HB762_05600	COG3706	GGDEF domain
HB762_05610	COG0602	queuosine metabolic process
HB762_05615	COG0561	phosphatase activity
HB762_05650	COG2828	Protein conserved in bacteria
HB762_05660	COG0372	Belongs to the citrate synthase family
HB762_05665	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HB762_05675	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HB762_05745	COG0730	response to heat
HB762_05755	COG2358	TRAP transporter, solute receptor (TAXI family
HB762_05760	COG1012	belongs to the aldehyde dehydrogenase family
HB762_05765	COG3284	Transcriptional regulator
HB762_05775	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HB762_05780	COG0363	glucosamine-6-phosphate deaminase activity
HB762_05785	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HB762_05790	COG4565	transcriptional regulatory protein
HB762_05795	COG3290	protein histidine kinase activity
HB762_05815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB762_05860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB762_05900	COG0456	acetyltransferase
HB762_06030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HB762_06035	COG0515	serine threonine protein kinase
HB762_06035	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HB762_06075	COG0625	glutathione transferase activity
HB762_06085	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HB762_06100	COG2195	Cleaves the N-terminal amino acid of tripeptides
HB762_06130	COG1562	ergosterol biosynthetic process
HB762_06185	COG1451	nucleotide metabolic process
HB762_06195	COG0583	DNA-binding transcription factor activity
HB762_06225	COG4139	cobalamin transport
HB762_06240	COG2062	phosphohistidine phosphatase, SixA
HB762_06250	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HB762_06260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HB762_06265	COG0702	epimerase
HB762_06270	COG1823	symporter activity
HB762_06280	COG2925	Exonuclease
HB762_06290	COG1346	cytolysis
HB762_06340	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB762_06345	COG4605	iron ion homeostasis
HB762_06350	COG4607	ABC-type enterochelin transport system periplasmic component
HB762_06355	COG4774	siderophore transport
HB762_06375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB762_06390	COG1132	(ABC) transporter
HB762_06395	COG1535	isochorismatase
HB762_06395	COG3433	isochorismatase activity
HB762_06400	COG0072	phenylalanine-tRNA ligase activity
HB762_06400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HB762_06450	COG0251	oxidation-reduction process
HB762_06495	COG2188	Transcriptional regulator
HB762_06505	COG0010	Belongs to the arginase family
HB762_06515	COG2986	histidine ammonia-lyase
HB762_06560	COG0247	lactate metabolic process
HB762_06560	COG0277	FAD linked oxidase domain protein
HB762_06620	COG1643	Atp-dependent helicase
HB762_06630	COG2949	membrane
HB762_06635	COG0471	metal ion transport
HB762_06655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HB762_06660	COG0492	ferredoxin-NADP+ reductase activity
HB762_06665	COG4988	ABC transporter
HB762_06670	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HB762_06700	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HB762_06710	COG4191	Histidine kinase
HB762_06710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB762_06725	COG3070	regulator of competence-specific genes
HB762_06735	COG2431	L-lysine efflux transmembrane transporter activity
HB762_06745	COG0076	glutamate decarboxylase activity
HB762_06750	COG1737	Transcriptional regulator
HB762_06760	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HB762_06770	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HB762_06800	COG4181	ATPase activity
HB762_06805	COG0534	Mate efflux family protein
HB762_06810	COG0702	epimerase
HB762_06820	COG2814	Major facilitator Superfamily
HB762_06825	COG1187	pseudouridine synthase activity
HB762_06830	COG1061	Type III restriction enzyme res subunit
HB762_06890	COG1358	cellular component organization or biogenesis
HB762_06910	COG2310	stress, protein
HB762_06925	COG3313	Fe-S protein
HB762_06935	COG0659	secondary active sulfate transmembrane transporter activity
HB762_06945	COG4134	Bacterial extracellular solute-binding protein
HB762_06950	COG4135	transport system, permease component
HB762_06955	COG4136	ATPase activity
HB762_06960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HB762_06970	COG2814	Major facilitator Superfamily
HB762_06985	COG0564	pseudouridine synthase activity
HB762_06990	COG0733	neurotransmitter:sodium symporter activity
HB762_07000	COG0626	cystathionine gamma-synthase activity
HB762_07005	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HB762_07025	COG2818	Glycosylase
HB762_07035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB762_07045	COG1983	PspC domain protein
HB762_07055	COG1842	Phage shock protein A
HB762_07060	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HB762_07070	COG4168	peptide transport system, permease
HB762_07075	COG4171	peptide transport system, permease
HB762_07085	COG4172	Belongs to the ABC transporter superfamily
HB762_07095	COG1227	inorganic diphosphatase activity
HB762_07100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB762_07105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB762_07110	COG1121	(ABC) transporter
HB762_07125	COG0243	molybdopterin cofactor binding
HB762_07130	COG3005	denitrification pathway
HB762_07135	COG4459	periplasmic nitrate reductase
HB762_07140	COG0390	transport system, permease component
HB762_07150	COG2116	formate transmembrane transporter activity
HB762_07170	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HB762_07175	COG1435	thymidine kinase activity
HB762_07180	COG0215	cysteine-tRNA ligase activity
HB762_07185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HB762_07190	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HB762_07195	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HB762_07200	COG3012	SEC-C Motif Domain Protein
HB762_07205	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HB762_07205	COG0140	phosphoribosyl-ATP diphosphatase activity
HB762_07220	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HB762_07225	COG0131	Imidazoleglycerol-phosphate dehydratase
HB762_07225	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HB762_07235	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HB762_07245	COG1757	Na H antiporter
HB762_07255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB762_07275	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HB762_07295	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HB762_07310	COG0300	oxidoreductase activity
HB762_07355	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HB762_07365	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HB762_07375	COG1674	ftsk spoiiie
HB762_07385	COG0686	Belongs to the AlaDH PNT family
HB762_07395	COG0583	DNA-binding transcription factor activity
HB762_07420	COG0402	S-adenosylhomocysteine deaminase activity
HB762_07425	COG4934	collagen metabolic process
HB762_07440	COG3568	Endonuclease Exonuclease Phosphatase
HB762_07460	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HB762_07475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB762_07480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB762_07490	COG2824	Alkylphosphonate utilization operon protein PhnA
HB762_07545	COG0457	Tetratricopeptide repeat
HB762_07615	COG4790	Type iii secretion
HB762_07620	COG4794	Type iii secretion
HB762_07625	COG4791	protein targeting
HB762_07630	COG4792	protein secretion
HB762_07635	COG0583	DNA-binding transcription factor activity
HB762_07645	COG3177	Filamentation induced by cAMP protein fic
HB762_07675	COG4669	(LipO)protein
HB762_07760	COG0515	serine threonine protein kinase
HB762_07760	COG2815	serine threonine protein kinase
HB762_07815	COG0514	ATP-dependent DNA helicase (RecQ)
HB762_07830	COG2205	protein histidine kinase activity
HB762_07830	COG0784	Response regulator, receiver
HB762_07840	COG0754	glutathionylspermidine amidase activity
HB762_07850	COG3766	membrane
HB762_07865	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HB762_07870	COG2885	chlorophyll binding
HB762_07875	COG0823	Involved in the tonB-independent uptake of proteins
HB762_07890	COG0811	peptide transport
HB762_07895	COG0824	Thioesterase
HB762_07905	COG4890	Cyd operon protein YbgT
HB762_07910	COG1294	oxidase, subunit
HB762_07915	COG1271	oxidase subunit
HB762_07925	COG0632	four-way junction helicase activity
HB762_07930	COG0840	transmembrane signaling receptor activity
HB762_07945	COG1801	Protein of unknown function DUF72
HB762_07960	COG0189	ligase activity
HB762_07960	COG4067	protein conserved in archaea
HB762_07980	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HB762_07985	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HB762_07995	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB762_08000	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HB762_08005	COG0745	RESPONSE REGULATOR receiver
HB762_08020	COG3070	regulator of competence-specific genes
HB762_08040	COG0297	glycogen (starch) synthase activity
HB762_08045	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HB762_08050	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HB762_08080	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HB762_08085	COG0542	response to heat
HB762_08095	COG1278	Cold shock
HB762_08105	COG1187	pseudouridine synthase activity
HB762_08110	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HB762_08120	COG1199	ATP-dependent helicase activity
HB762_08125	COG0730	response to heat
HB762_08130	COG3923	Primosomal replication protein n
HB762_08140	COG0708	Exodeoxyribonuclease III
HB762_08175	COG1882	Formate acetyltransferase
HB762_08185	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HB762_08200	COG2766	serine protein kinase
HB762_08205	COG2718	Belongs to the UPF0229 family
HB762_08210	COG2719	SpoVR family
HB762_08230	COG1132	(ABC) transporter
HB762_08235	COG0658	competence protein
HB762_08235	COG2333	competence protein COMEC
HB762_08245	COG4591	ABC-type transport system involved in lipoprotein release permease component
HB762_08250	COG1136	(ABC) transporter
HB762_08255	COG4591	ABC-type transport system involved in lipoprotein release permease component
HB762_08265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HB762_08280	COG1252	NADH dehydrogenase
HB762_08310	COG0537	adenosine 5'-monophosphoramidase activity
HB762_08330	COG2217	Heavy metal translocating P-type atpase
HB762_08340	COG0516	GMP reductase activity
HB762_08340	COG0517	IMP dehydrogenase activity
HB762_08345	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
HB762_08350	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HB762_08355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB762_08430	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HB762_08500	COG3706	GGDEF domain
HB762_08515	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HB762_08520	COG1946	Acyl-CoA thioesterase
HB762_08525	COG1522	sequence-specific DNA binding
HB762_08545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB762_08600	COG2855	membrane
HB762_08610	COG0583	DNA-binding transcription factor activity
HB762_08615	COG2190	(PTS) system
HB762_08615	COG1263	PTS System
HB762_08615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB762_08630	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HB762_08635	COG0596	Alpha beta hydrolase
HB762_08645	COG1169	isochorismate synthase
HB762_08650	COG0436	Aminotransferase
HB762_08655	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HB762_08675	COG1555	photosystem II stabilization
HB762_08680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB762_08685	COG0776	regulation of translation
HB762_08690	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HB762_08725	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HB762_08730	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HB762_08735	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HB762_08755	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HB762_08760	COG0569	domain protein
HB762_08765	COG0513	Belongs to the DEAD box helicase family
HB762_08775	COG4771	TonB-dependent receptor
HB762_08780	COG2977	Belongs to the P-Pant transferase superfamily
HB762_08790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB762_08795	COG1535	isochorismatase
HB762_08795	COG3433	isochorismatase activity
HB762_08800	COG1021	2,3-dihydroxybenzoate-AMP ligase
HB762_08805	COG1169	isochorismate synthase
HB762_08815	COG1028	Short-chain dehydrogenase reductase Sdr
HB762_08825	COG2226	methyltransferase
HB762_08925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB762_08935	COG2951	lytic endotransglycosylase activity
HB762_08950	COG2894	cell division
HB762_08955	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HB762_08960	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HB762_08965	COG0318	PFAM AMP-dependent synthetase and ligase
HB762_08970	COG2267	carboxylic ester hydrolase activity
HB762_08975	COG3065	identical protein binding
HB762_08985	COG1214	PFAM Peptidase M22, glycoprotease
HB762_08990	COG1199	ATP-dependent helicase activity
HB762_08995	COG0788	formyltetrahydrofolate deformylase activity
HB762_09005	COG3102	Protein conserved in bacteria
HB762_09035	COG1918	ferrous iron import across plasma membrane
HB762_09040	COG4977	sequence-specific DNA binding
HB762_09045	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HB762_09050	COG1121	(ABC) transporter
HB762_09055	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB762_09070	COG0508	dehydrogenase complex catalyzes the overall conversion of
HB762_09075	COG0567	Dehydrogenase, E1 component
HB762_09085	COG1053	succinate dehydrogenase
HB762_09090	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HB762_09105	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HB762_09115	COG0033	Phosphoglucomutase
HB762_09120	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HB762_09125	COG0596	Alpha beta hydrolase
HB762_09145	COG0735	belongs to the Fur family
HB762_09150	COG2165	general secretion pathway protein
HB762_09160	COG2190	(PTS) system
HB762_09160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB762_09160	COG1263	PTS System
HB762_09165	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HB762_09170	COG1940	carbohydrate kinase activity
HB762_09170	COG1846	Transcriptional regulator
HB762_09175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HB762_09175	COG4651	solute:proton antiporter activity
HB762_09180	COG0367	asparagine synthase
HB762_09185	COG0250	Participates in transcription elongation, termination and antitermination
HB762_09190	COG3104	oligopeptide transport
HB762_09195	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HB762_09210	COG3710	Transcriptional regulator
HB762_09230	COG0622	Phosphoesterase
HB762_09240	COG1090	epimerase
HB762_09245	COG0300	oxidoreductase activity
HB762_09250	COG3118	belongs to the thioredoxin family
HB762_09255	COG0330	HflC and HflK could
HB762_09295	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
HB762_09300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HB762_09305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB762_09310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HB762_09315	COG2190	(PTS) system
HB762_09320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB762_09325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB762_09330	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB762_09350	COG3951	Flagellar rod assembly protein muramidase FlgJ
HB762_09350	COG1705	Flagellar rod assembly protein muramidase FlgJ
HB762_09355	COG1706	bacterial-type flagellum-dependent cell motility
HB762_09360	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HB762_09370	COG4787	bacterial-type flagellum-dependent cell motility
HB762_09375	COG1749	Flagellar hook protein flgE
HB762_09385	COG1558	bacterial-type flagellum-dependent cell motility
HB762_09390	COG1815	bacterial-type flagellum-dependent cell motility
HB762_09395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HB762_09400	COG0835	chemotaxis
HB762_09400	COG0784	Response regulator, receiver
HB762_09455	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HB762_09465	COG2217	Heavy metal translocating P-type atpase
HB762_09465	COG2608	mercury ion transmembrane transporter activity
HB762_09505	COG2840	Smr protein MutS2
HB762_09510	COG1187	pseudouridine synthase activity
HB762_09515	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HB762_09520	COG0737	Belongs to the 5'-nucleotidase family
HB762_09530	COG2912	Transglutaminase-like superfamily
HB762_09535	COG3094	Invasion gene expression up-regulator, SirB
HB762_09540	COG2890	protein-(glutamine-N5) methyltransferase activity
HB762_09565	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HB762_09685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB762_09695	COG1702	phosphate starvation-inducible protein PhoH
HB762_09705	COG4535	Mg2 and Co2 transporter CorC
HB762_09710	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HB762_09715	COG2888	peptidyl-tyrosine sulfation
HB762_09725	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
HB762_09730	COG1466	dna polymerase III delta subunit
HB762_09735	COG0799	negative regulation of ribosome biogenesis
HB762_09745	COG0768	penicillin binding
HB762_09750	COG0772	Belongs to the SEDS family
HB762_09755	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HB762_09760	COG1686	Belongs to the peptidase S11 family
HB762_09780	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HB762_09785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HB762_09790	COG0366	Alpha amylase catalytic
HB762_09795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB762_09795	COG1263	PTS System
HB762_09805	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HB762_09810	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HB762_09815	COG2011	ABC-type metal ion transport system permease component
HB762_09820	COG1464	Belongs to the NlpA lipoprotein family
HB762_09835	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
HB762_09860	COG1611	Belongs to the LOG family
HB762_09875	COG2363	Small membrane protein
HB762_09885	COG0583	DNA-binding transcription factor activity
HB762_09900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HB762_09910	COG0142	geranyltranstransferase activity
HB762_09920	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HB762_09925	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HB762_09950	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HB762_09950	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HB762_09955	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HB762_09960	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HB762_09975	COG1073	alpha beta
HB762_09985	COG2252	PERMEase
HB762_09990	COG2195	Cleaves the N-terminal amino acid of tripeptides
HB762_10015	COG0047	phosphoribosylformylglycinamidine synthase activity
HB762_10015	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HB762_10025	COG0590	tRNA wobble adenosine to inosine editing
HB762_10030	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HB762_10050	COG4969	Belongs to the N-Me-Phe pilin family
HB762_10065	COG0443	Heat shock 70 kDa protein
HB762_10070	COG1301	dicarboxylic acid transport
HB762_10085	COG0497	DNA recombination
HB762_10090	COG0456	acetyltransferase
HB762_10095	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB762_10100	COG2914	Belongs to the UPF0125 (RnfH) family
HB762_10105	COG2867	negative regulation of translational initiation
HB762_10120	COG0583	DNA-binding transcription factor activity
HB762_10125	COG1289	transmembrane transporter activity
HB762_10140	COG4974	Belongs to the 'phage' integrase family
HB762_10255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HB762_10270	COG0668	transmembrane transport
HB762_10275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HB762_10280	COG0583	DNA-binding transcription factor activity
HB762_10285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB762_10290	COG1115	amino acid carrier protein
HB762_10295	COG1584	GPR1 FUN34 yaaH family protein
HB762_10305	COG1757	Na H antiporter
HB762_10315	COG0517	IMP dehydrogenase activity
HB762_10315	COG0516	GMP reductase activity
HB762_10330	COG2199	diguanylate cyclase activity
HB762_10330	COG2203	Gaf domain
HB762_10345	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB762_10350	COG2976	Protein conserved in bacteria
HB762_10385	COG2975	iron-sulfur cluster assembly
HB762_10390	COG0633	Ferredoxin
HB762_10405	COG0316	Belongs to the HesB IscA family
HB762_10410	COG0822	iron-sulfur transferase activity
HB762_10425	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HB762_10430	COG0483	inositol monophosphate 1-phosphatase activity
HB762_10435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB762_10440	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB762_10445	COG1862	Preprotein translocase
HB762_10465	COG0517	IMP dehydrogenase activity
HB762_10475	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HB762_10480	COG0583	DNA-binding transcription factor activity
HB762_10485	COG0450	alkyl hydroperoxide reductase
HB762_10500	COG0704	Plays a role in the regulation of phosphate uptake
HB762_10505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HB762_10510	COG0581	inorganic phosphate transmembrane transporter activity
HB762_10515	COG0573	inorganic phosphate transmembrane transporter activity
HB762_10520	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HB762_10525	COG0248	Ppx GppA phosphatase
HB762_10535	COG5002	protein histidine kinase activity
HB762_10540	COG0745	RESPONSE REGULATOR receiver
HB762_10550	COG0826	peptidase U32
HB762_10555	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB762_10610	COG0542	response to heat
HB762_10620	COG0564	pseudouridine synthase activity
HB762_10625	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB762_10630	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HB762_10635	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HB762_10640	COG1605	Chorismate mutase
HB762_10640	COG0077	Prephenate dehydratase
HB762_10645	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
HB762_10660	COG0488	(ABC) transporter
HB762_10670	COG0739	heme binding
HB762_10675	COG1605	Chorismate mutase
HB762_10675	COG0287	Prephenate dehydrogenase
HB762_10680	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB762_10690	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HB762_10710	COG1966	Carbon starvation protein
HB762_10715	COG3275	phosphorelay sensor kinase activity
HB762_10720	COG3279	Response regulator of the LytR AlgR family
HB762_10725	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HB762_10730	COG1047	Peptidyl-prolyl cis-trans
HB762_10745	COG0196	riboflavin kinase activity
HB762_10750	COG0728	peptidoglycan biosynthetic process
HB762_10755	COG0268	Binds directly to 16S ribosomal RNA
HB762_10760	COG0640	Transcriptional regulator
HB762_10765	COG0583	DNA-binding transcription factor activity
HB762_10770	COG1283	sodium-dependent phosphate transmembrane transporter activity
HB762_10785	COG0730	response to heat
HB762_10810	COG0667	Aldo Keto reductase
HB762_10835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HB762_10840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB762_10845	COG4974	Belongs to the 'phage' integrase family
HB762_10850	COG0716	FMN binding
HB762_10865	COG0513	Belongs to the DEAD box helicase family
HB762_10875	COG3022	response to hydroperoxide
HB762_10880	COG1115	amino acid carrier protein
HB762_10905	COG0431	NADPH-dependent FMN reductase
HB762_10910	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HB762_10915	COG0083	homoserine kinase activity
HB762_10930	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HB762_10940	COG0745	RESPONSE REGULATOR receiver
HB762_10950	COG0784	Response regulator, receiver
HB762_10950	COG2198	Histidine kinase
HB762_10950	COG5002	protein histidine kinase activity
HB762_10955	COG2203	Gaf domain
HB762_10955	COG3706	GGDEF domain
HB762_10955	COG4251	negative regulation of phosphorylation
HB762_10955	COG5001	Diguanylate cyclase
HB762_10960	COG1242	4 iron, 4 sulfur cluster binding
HB762_10965	COG0067	glutamate synthase
HB762_10965	COG0070	glutamate synthase
HB762_10965	COG0069	glutamate synthase activity
HB762_10975	COG0069	glutamate synthase activity
HB762_10975	COG0067	glutamate synthase
HB762_10975	COG0070	glutamate synthase
HB762_10980	COG0493	'glutamate synthase
HB762_11005	COG2860	membrane
HB762_11010	COG0583	DNA-binding transcription factor activity
HB762_11015	COG0730	response to heat
HB762_11020	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HB762_11025	COG0505	Belongs to the CarA family
HB762_11035	COG0494	nUDIX hydrolase
HB762_11055	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HB762_11060	COG0849	cell division
HB762_11065	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HB762_11080	COG0772	Belongs to the SEDS family
HB762_11095	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HB762_11100	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HB762_11105	COG0768	penicillin binding
HB762_11110	COG3116	cell division
HB762_11125	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HB762_11140	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HB762_11145	COG2823	Periplasmic or secreted lipoprotein
HB762_11150	COG2969	positive regulation of protein catabolic process
HB762_11155	COG0625	glutathione transferase activity
HB762_11160	COG2857	Cytochrome c1
HB762_11165	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HB762_11170	COG0723	plastoquinol--plastocyanin reductase activity
HB762_11185	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HB762_11190	COG3105	Protein conserved in bacteria
HB762_11195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HB762_11200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HB762_11205	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HB762_11215	COG3150	esterase
HB762_11225	COG3151	Protein conserved in bacteria
HB762_11230	COG0494	nUDIX hydrolase
HB762_11235	COG1538	Outer membrane efflux protein
HB762_11245	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HB762_11255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HB762_11260	COG3025	triphosphatase activity
HB762_11265	COG1392	Phosphate transport regulator
HB762_11270	COG0306	phosphate transporter
HB762_11275	COG4991	sh3 domain protein
HB762_11285	COG3267	Type II secretory pathway component ExeA
HB762_11285	COG3409	Peptidoglycan-binding domain 1 protein
HB762_11300	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HB762_11305	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HB762_11315	COG0596	Alpha beta hydrolase
HB762_11320	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HB762_11325	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HB762_11330	COG1610	YqeY-like protein
HB762_11335	COG0358	DNA primase activity
HB762_11380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HB762_11385	COG1349	DNA-binding transcription factor activity
HB762_11390	COG0469	pyruvate kinase activity
HB762_11400	COG3706	GGDEF domain
HB762_11405	COG0440	acetolactate synthase activity
HB762_11410	COG0028	Belongs to the TPP enzyme family
HB762_11415	COG1022	Amp-dependent synthetase and ligase
HB762_11420	COG0583	DNA-binding transcription factor activity
HB762_11440	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HB762_11445	COG0473	3-isopropylmalate dehydrogenase activity
HB762_11465	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HB762_11470	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HB762_11475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB762_11480	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HB762_11500	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HB762_11505	COG3610	response to peptide
HB762_11510	COG2966	Psort location CytoplasmicMembrane, score
HB762_11525	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HB762_11530	COG0142	geranyltranstransferase activity
HB762_11550	COG2358	TRAP transporter, solute receptor (TAXI family
HB762_11565	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HB762_11570	COG1178	ABC-type Fe3 transport system permease component
HB762_11575	COG4143	(ABC) transporter
HB762_11580	COG0163	prenyltransferase activity
HB762_11585	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HB762_11595	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HB762_11605	COG2105	PFAM AIG2 family protein
HB762_11610	COG2911	Protein conserved in bacteria
HB762_11620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB762_11630	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HB762_11645	COG1136	(ABC) transporter
HB762_11665	COG0529	Catalyzes the synthesis of activated sulfate
HB762_11670	COG0471	metal ion transport
HB762_11670	COG3273	potassium ion transport
HB762_11685	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HB762_11685	COG1648	precorrin-2 dehydrogenase activity
HB762_11690	COG0737	Belongs to the 5'-nucleotidase family
HB762_11700	COG0513	Belongs to the DEAD box helicase family
HB762_11705	COG2153	protein acetylation
HB762_11720	COG0545	Peptidyl-prolyl cis-trans isomerase
HB762_11730	COG0203	ribosomal protein L17
HB762_11735	COG0202	RNA polymerase activity
HB762_11745	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HB762_11750	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HB762_11755	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HB762_11760	COG0201	protein transport
HB762_11770	COG1841	ribosomal large subunit assembly
HB762_11855	COG0088	Forms part of the polypeptide exit tunnel
HB762_11875	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HB762_11880	COG1609	Transcriptional regulator
HB762_11900	COG1575	Belongs to the MenA family. Type 1 subfamily
HB762_11905	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HB762_11915	COG1494	fructose-1,6-bisphosphatase
HB762_11945	COG0149	triose-phosphate isomerase activity
HB762_11950	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HB762_11965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HB762_11970	COG1216	Glycosyl transferase, family 2
HB762_11980	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HB762_11985	COG0463	Glycosyl transferase, family 2
HB762_12000	COG1181	Belongs to the D-alanine--D-alanine ligase family
HB762_12005	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HB762_12065	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB762_12075	COG1560	Kdo2-lipid A biosynthetic process
HB762_12090	COG1519	Transferase
HB762_12110	COG3642	lipopolysaccharide core region biosynthetic process
HB762_12115	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HB762_12120	COG0859	PFAM glycosyl transferase family 9
HB762_12125	COG0463	Glycosyl transferase, family 2
HB762_12140	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HB762_12160	COG2194	sulfuric ester hydrolase activity
HB762_12180	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HB762_12190	COG1560	Kdo2-lipid A biosynthetic process
HB762_12195	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HB762_12200	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HB762_12205	COG1561	YicC-like family, N-terminal region
HB762_12215	COG4608	Belongs to the ABC transporter superfamily
HB762_12220	COG0444	Belongs to the ABC transporter superfamily
HB762_12230	COG4239	(ABC) transporter, permease
HB762_12235	COG4174	ABC transporter (Permease)
HB762_12255	COG0811	peptide transport
HB762_12260	COG0848	biopolymer transport protein
HB762_12275	COG0194	GDP metabolic process
HB762_12280	COG1758	RNA polymerase activity
HB762_12285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HB762_12290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB762_12295	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HB762_12305	COG2233	PERMEase
HB762_12320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB762_12330	COG2183	response to ionizing radiation
HB762_12355	COG0494	nUDIX hydrolase
HB762_12360	COG1218	3'(2'),5'-bisphosphate nucleotidase
HB762_12370	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HB762_12375	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HB762_12380	COG3156	type II secretion system protein K
HB762_12385	COG4795	General secretion pathway protein
HB762_12390	COG2165	general secretion pathway protein
HB762_12395	COG2165	general secretion pathway protein
HB762_12400	COG2165	general secretion pathway protein
HB762_12405	COG1459	type II secretion system
HB762_12410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB762_12420	COG3031	protein transport across the cell outer membrane
HB762_12425	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HB762_12445	COG0456	acetyltransferase
HB762_12450	COG1490	D-aminoacyl-tRNA deacylase activity
HB762_12470	COG1217	gtp-binding protein TYPA
HB762_12475	COG0174	glutamine synthetase
HB762_12485	COG3852	Histidine kinase
HB762_12490	COG2204	response regulator
HB762_12500	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HB762_12530	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HB762_12535	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HB762_12535	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HB762_12550	COG0084	hydrolase, TatD family'
HB762_12555	COG0805	protein transport
HB762_12560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HB762_12575	COG3165	ubiquinone biosynthetic process from chorismate
HB762_12585	COG1322	Protein conserved in bacteria
HB762_12600	COG1910	domain protein
HB762_12620	COG2081	HI0933 family
HB762_12630	COG1528	Iron-storage protein
HB762_12635	COG0589	response to stress
HB762_12655	COG5001	Diguanylate cyclase
HB762_12655	COG5002	protein histidine kinase activity
HB762_12660	COG1522	sequence-specific DNA binding
HB762_12670	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HB762_12680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB762_12685	COG0800	Aldolase
HB762_12700	COG0515	serine threonine protein kinase
HB762_12730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB762_12735	COG0601	transmembrane transport
HB762_12740	COG4166	transmembrane transport
HB762_12745	COG4172	Belongs to the ABC transporter superfamily
HB762_12795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB762_12800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB762_12805	COG2960	long-chain fatty acid transporting porin activity
HB762_12810	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HB762_12815	COG0583	DNA-binding transcription factor activity
HB762_12860	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HB762_12885	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HB762_12890	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HB762_12895	COG0551	DNA topoisomerase type I activity
HB762_12905	COG0758	DNA mediated transformation
HB762_12915	COG0242	peptide deformylase activity
HB762_12925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HB762_12925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HB762_12930	COG0569	domain protein
HB762_12935	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HB762_12945	COG1272	protein, Hemolysin III
HB762_12950	COG4326	sporulation control protein
HB762_12960	COG3084	Protein conserved in bacteria
HB762_12970	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HB762_12975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB762_12980	COG0204	Acyl-transferase
HB762_12990	COG2199	diguanylate cyclase activity
HB762_12995	COG0606	chelatase, subunit chli
HB762_13005	COG3978	acetolactate synthase activity
HB762_13010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HB762_13015	COG0129	dihydroxy-acid dehydratase activity
HB762_13025	COG0583	DNA-binding transcription factor activity
HB762_13030	COG2814	Major facilitator Superfamily
HB762_13035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB762_13040	COG0765	amino acid transport
HB762_13050	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HB762_13060	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HB762_13090	COG3312	ion transport
HB762_13095	COG1475	DNA binding
HB762_13100	COG1192	Involved in chromosome partitioning
HB762_13115	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HB762_13145	COG1126	abc transporter atp-binding protein
HB762_13165	COG0592	DNA-directed DNA polymerase activity
HB762_13175	COG0187	DNA topoisomerase II activity
HB762_13180	COG0071	Belongs to the small heat shock protein (HSP20) family
HB762_13185	COG3977	Valine--pyruvate aminotransferase
HB762_13200	COG2119	membrane
HB762_13225	COG0604	alcohol dehydrogenase
HB762_13230	COG0183	Belongs to the thiolase family
HB762_13240	COG1739	Uncharacterized protein family UPF0029
HB762_13245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HB762_13290	COG2132	Multicopper oxidase
HB762_13310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HB762_13315	COG2104	thiamine diphosphate biosynthetic process
HB762_13330	COG0006	proline dipeptidase activity
HB762_13330	COG0006	proline dipeptidase activity
HB762_13360	COG3220	belongs to the UPF0276 family
HB762_13370	COG0210	DNA helicase
HB762_13375	COG0405	Gamma-glutamyltransferase
HB762_13380	COG1280	lysine exporter protein (LysE YggA)
HB762_13390	COG2962	Rard protein
HB762_13395	COG0514	ATP-dependent DNA helicase (RecQ)
HB762_13405	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HB762_13420	COG3118	belongs to the thioredoxin family
HB762_13435	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HB762_13440	COG0633	Ferredoxin
HB762_13480	COG3071	HemY protein
HB762_13485	COG2959	enzyme of heme biosynthesis
HB762_13490	COG1587	Uroporphyrinogen-III synthase
HB762_13500	COG3072	Adenylate cyclase
HB762_13515	COG0019	diaminopimelate decarboxylase activity
HB762_13535	COG1011	Hydrolase
HB762_13540	COG2199	diguanylate cyclase activity
HB762_13540	COG3287	FIST C domain
HB762_13540	COG2200	EAL domain
HB762_13545	COG3148	PFAM DTW domain containing protein
HB762_13560	COG0561	phosphatase activity
HB762_13565	COG2267	carboxylic ester hydrolase activity
HB762_13570	COG1280	lysine exporter protein (LysE YggA)
HB762_13575	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HB762_13580	COG0640	Transcriptional regulator
HB762_13585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HB762_13630	COG2095	MarC family integral membrane protein
HB762_13640	COG0742	ribosomal rna small subunit methyltransferase
HB762_13645	COG0552	protein localization to endoplasmic reticulum
HB762_13650	COG2884	Cell division ATP-binding protein ftsE
HB762_13655	COG2177	Part of the ABC transporter FtsEX involved in
HB762_13670	COG0705	Rhomboid family
HB762_13675	COG1580	Controls the rotational direction of flagella during chemotaxis
HB762_13680	COG3161	chorismate lyase activity
HB762_13690	COG2937	Belongs to the GPAT DAPAT family
HB762_13705	COG0534	Mate efflux family protein
HB762_13710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB762_13730	COG4206	TonB-dependent receptor
HB762_13810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HB762_13820	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HB762_13860	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HB762_13865	COG0250	Participates in transcription elongation, termination and antitermination
HB762_13880	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HB762_13900	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HB762_13905	COG2816	NAD+ diphosphatase activity
HB762_13915	COG1573	uracil-dna glycosylase
HB762_13925	COG3068	Protein conserved in bacteria
HB762_13930	COG1253	flavin adenine dinucleotide binding
HB762_13945	COG0151	Belongs to the GarS family
HB762_13955	COG0789	Transcriptional regulator
HB762_13960	COG3710	Transcriptional regulator
HB762_14015	COG2199	diguanylate cyclase activity
HB762_14020	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HB762_14025	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HB762_14035	COG0439	Biotin carboxylase
HB762_14040	COG0511	ligase activity, forming carbon-carbon bonds
HB762_14045	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HB762_14050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HB762_14065	COG2814	Major facilitator Superfamily
HB762_14070	COG2198	Histidine kinase
HB762_14070	COG0784	Response regulator, receiver
HB762_14070	COG2205	protein histidine kinase activity
HB762_14090	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HB762_14100	COG2095	MarC family integral membrane protein
HB762_14110	COG4232	protein-disulfide reductase activity
HB762_14115	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HB762_14120	COG1027	Aspartate ammonia-lyase
HB762_14125	COG3030	protein affecting phage T7 exclusion by the F plasmid
HB762_14130	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HB762_14140	COG2205	protein histidine kinase activity
HB762_14145	COG0745	RESPONSE REGULATOR receiver
HB762_14155	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HB762_14165	COG0534	Mate efflux family protein
HB762_14195	COG1509	lysine 2,3-aminomutase activity
HB762_14225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HB762_14230	COG1053	succinate dehydrogenase
HB762_14255	COG4942	peptidase
HB762_14260	COG1045	serine acetyltransferase
HB762_14275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HB762_14280	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HB762_14290	COG0840	transmembrane signaling receptor activity
HB762_14295	COG0471	metal ion transport
HB762_14305	COG1162	GTPase activity
HB762_14385	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HB762_14390	COG0802	atpase or kinase
HB762_14395	COG0860	N-Acetylmuramoyl-L-alanine amidase
HB762_14400	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HB762_14415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HB762_14420	COG0330	HflC and HflK could
HB762_14425	COG0330	HflC and HflK could
HB762_14430	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HB762_14435	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HB762_14440	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HB762_14445	COG1017	nitric oxide dioxygenase activity
HB762_14445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB762_14455	COG0557	exoribonuclease II activity
HB762_14460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB762_14465	COG0546	phosphoglycolate phosphatase activity
HB762_14485	COG0512	Glutamine amidotransferase of anthranilate synthase
HB762_14490	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HB762_14510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB762_14515	COG3954	Phosphoribulokinase
HB762_14525	COG0429	hydrolase of the alpha beta-hydrolase fold
HB762_14535	COG0488	(ABC) transporter
HB762_14540	COG2249	NAD(P)H dehydrogenase (quinone) activity
HB762_14555	COG1047	Peptidyl-prolyl cis-trans
HB762_14560	COG1446	asparaginase
HB762_14575	COG0545	Peptidyl-prolyl cis-trans isomerase
HB762_14580	COG2964	Protein conserved in bacteria
HB762_14585	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HB762_14590	COG2923	Belongs to the DsrF TusC family
HB762_14595	COG2168	tRNA wobble position uridine thiolation
HB762_14610	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HB762_14620	COG2906	2 iron, 2 sulfur cluster binding
HB762_14630	COG0281	malic enzyme
HB762_14640	COG0626	cystathionine gamma-synthase activity
HB762_14645	COG0527	aspartate kinase activity
HB762_14645	COG0460	homoserine dehydrogenase
HB762_14650	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HB762_14660	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HB762_14670	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HB762_14685	COG0165	Argininosuccinate lyase
HB762_14685	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HB762_14695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB762_14700	COG0678	peroxiredoxin activity
HB762_14700	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HB762_14710	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HB762_14755	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HB762_14760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HB762_14770	COG2965	DNA replication, synthesis of RNA primer
HB762_14790	COG0305	Participates in initiation and elongation during chromosome replication
HB762_14795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HB762_14805	COG0432	Pfam Uncharacterised protein family UPF0047
HB762_14820	COG0735	belongs to the Fur family
HB762_14825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HB762_14845	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HB762_14910	COG0646	methionine synthase
HB762_14910	COG1410	methionine synthase
HB762_14915	COG0527	aspartate kinase activity
HB762_14920	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HB762_14930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HB762_14945	COG0629	single-stranded DNA binding
HB762_14950	COG2199	diguanylate cyclase activity
HB762_14950	COG2200	EAL domain
HB762_14975	COG3409	Peptidoglycan-binding domain 1 protein
HB762_14975	COG3267	Type II secretory pathway component ExeA
HB762_14985	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB762_14990	COG1459	type II secretion system
HB762_15000	COG2165	general secretion pathway protein
HB762_15035	COG1077	Cell shape determining protein MreB Mrl
HB762_15040	COG1792	Involved in formation and maintenance of cell shape
HB762_15045	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HB762_15050	COG0424	maF-like protein
HB762_15060	COG3164	Protein of unknown function
HB762_15065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HB762_15070	COG0312	modulator of DNA gyrase
HB762_15075	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HB762_15090	COG0564	pseudouridine synthase activity
HB762_15095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HB762_15105	COG0312	modulator of DNA gyrase
HB762_15110	COG2239	Acts as a magnesium transporter
HB762_15115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB762_15125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB762_15130	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HB762_15140	COG1137	ATPase activity
HB762_15145	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HB762_15155	COG0517	IMP dehydrogenase activity
HB762_15155	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HB762_15165	COG1127	ABC transporter
HB762_15170	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HB762_15175	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HB762_15180	COG2854	intermembrane phospholipid transfer
HB762_15190	COG5007	Belongs to the BolA IbaG family
HB762_15200	COG0204	Acyl-transferase
HB762_15205	COG0251	oxidation-reduction process
HB762_15245	COG0456	acetyltransferase
HB762_15255	COG0525	valine-tRNA ligase activity
HB762_15260	COG2927	DNA polymerase III (CHI subunit)
HB762_15270	COG0795	lipopolysaccharide-transporting ATPase activity
HB762_15275	COG0795	lipopolysaccharide-transporting ATPase activity
HB762_15285	COG1028	Short-chain dehydrogenase reductase Sdr
HB762_15295	COG0726	polysaccharide deacetylase
HB762_15310	COG1447	Phosphotransferase system cellobiose-specific component IIA
HB762_15315	COG1486	melibiose metabolic process
HB762_15325	COG1609	Transcriptional regulator
HB762_15380	COG1012	belongs to the aldehyde dehydrogenase family
HB762_15480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HB762_15485	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HB762_15500	COG0762	integral membrane protein
HB762_15505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HB762_15510	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HB762_15525	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HB762_15530	COG1678	Uncharacterized ACR, COG1678
HB762_15535	COG0189	ligase activity
HB762_15540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HB762_15545	COG2356	endonuclease I
HB762_15565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HB762_15585	COG0191	fructose-bisphosphate aldolase activity
HB762_15590	COG0668	transmembrane transport
HB762_15605	COG0583	DNA-binding transcription factor activity
HB762_15615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HB762_15625	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HB762_15635	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HB762_15645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB762_15650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB762_15670	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HB762_15680	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HB762_15685	COG1595	DNA-templated transcription, initiation
HB762_15700	COG3086	response to oxidative stress
HB762_15720	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HB762_15725	COG1381	Involved in DNA repair and RecF pathway recombination
HB762_15730	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HB762_15750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HB762_15755	COG3956	TIGRFAM MazG family protein
HB762_15765	COG0148	phosphopyruvate hydratase activity
HB762_15775	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HB762_15805	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HB762_15815	COG1546	Belongs to the CinA family
HB762_15820	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HB762_15835	COG0527	aspartate kinase activity
HB762_15925	COG3630	sodium ion export across plasma membrane
HB762_15930	COG0511	ligase activity, forming carbon-carbon bonds
HB762_15930	COG5016	pyruvate
HB762_15935	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HB762_15945	COG1238	metal cluster binding
HB762_15950	COG0612	Peptidase, M16
HB762_15970	COG4536	flavin adenine dinucleotide binding
HB762_15975	COG4137	Cytochrome C assembly protein
HB762_15980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HB762_15985	COG0228	four-way junction DNA binding
HB762_16005	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HB762_16010	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HB762_16015	COG0237	dephospho-CoA kinase activity
HB762_16025	COG1459	type II secretion system
HB762_16030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB762_16050	COG2186	Transcriptional regulator
HB762_16055	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HB762_16075	COG2204	response regulator
HB762_16090	COG3501	Rhs element vgr protein
HB762_16115	COG0515	serine threonine protein kinase
HB762_16150	COG1522	sequence-specific DNA binding
HB762_16530	COG0778	Nitroreductase
HB762_16535	COG0784	Response regulator, receiver
HB762_16535	COG0835	chemotaxis
HB762_16545	COG2962	Rard protein
HB762_16555	COG0671	phosphoesterase, PA-phosphatase related
HB762_16595	COG5642	Protein of unknown function (DUF2384)
HB762_16605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HB762_16605	COG2755	lipolytic protein G-D-S-L family
HB762_16630	COG0840	transmembrane signaling receptor activity
HB762_16645	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HB762_16650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HB762_16675	COG0420	3'-5' exonuclease activity
HB762_16680	COG0419	ATPase involved in DNA repair
HB762_16690	COG3469	chitinase activity
HB762_16720	COG3040	lipid binding
HB762_16740	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HB762_16755	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HB762_16770	COG0583	DNA-binding transcription factor activity
HB762_16775	COG0277	FAD linked oxidase domain protein
HB762_16845	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HB762_16850	COG0840	transmembrane signaling receptor activity
HB762_16875	COG3118	belongs to the thioredoxin family
HB762_16880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HB762_16935	COG1328	CTP reductase activity
HB762_16940	COG0602	queuosine metabolic process
HB762_16950	COG2207	Transcriptional regulator
HB762_16970	COG3111	PFAM Bacterial OB fold (BOF) protein
HB762_16980	COG0725	ABC transporter, periplasmic molybdate-binding protein
HB762_16985	COG4149	molybdate abc transporter
HB762_16990	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HB762_17000	COG3706	GGDEF domain
HB762_17000	COG5001	Diguanylate cyclase
HB762_17000	COG4251	negative regulation of phosphorylation
HB762_17000	COG2203	Gaf domain
HB762_17020	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HB762_17025	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HB762_17050	COG3140	Belongs to the UPF0181 family
HB762_17065	COG0023	Translation Initiation Factor
HB762_17085	COG0045	succinate-CoA ligase (ADP-forming) activity
HB762_17085	COG1042	CoA-binding domain protein
HB762_17085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB762_17090	COG0583	DNA-binding transcription factor activity
HB762_17100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HB762_17105	COG3447	MASE1 domain protein
HB762_17105	COG5001	Diguanylate cyclase
HB762_17105	COG5002	protein histidine kinase activity
HB762_17115	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HB762_17120	COG1984	allophanate hydrolase subunit 2
HB762_17130	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HB762_17135	COG4181	ATPase activity
HB762_17145	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HB762_17150	COG5001	Diguanylate cyclase
HB762_17150	COG3300	MHYT domain
HB762_17160	COG0484	heat shock protein binding
HB762_17195	COG2050	protein possibly involved in aromatic compounds catabolism
HB762_17200	COG0501	Belongs to the peptidase M48B family
HB762_17210	COG2067	long-chain fatty acid transport protein
HB762_17215	COG2267	carboxylic ester hydrolase activity
HB762_17370	COG0076	glutamate decarboxylase activity
HB762_17375	COG0646	methionine synthase
HB762_17375	COG1410	methionine synthase
HB762_17390	COG0737	Belongs to the 5'-nucleotidase family
HB762_17395	COG3593	DNA synthesis involved in DNA repair
HB762_17405	COG0583	DNA-binding transcription factor activity
HB762_17410	COG2116	formate transmembrane transporter activity
HB762_17420	COG3038	cytochrome b561
HB762_17435	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HB762_17440	COG0513	Belongs to the DEAD box helicase family
HB762_17445	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HB762_17455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB762_17460	COG3437	response regulator, receiver
HB762_17475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB762_17485	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HB762_17495	COG2207	Transcriptional regulator
HB762_17500	COG1979	alcohol dehydrogenase
HB762_17510	COG1126	abc transporter atp-binding protein
HB762_17515	COG0765	amino acid transport
HB762_17520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB762_17525	COG0765	amino acid transport
HB762_17530	COG2200	EAL domain
HB762_17530	COG2203	Gaf domain
HB762_17530	COG2199	diguanylate cyclase activity
HB762_17545	COG1609	Transcriptional regulator
HB762_17550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB762_17550	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB762_17555	COG1105	Belongs to the carbohydrate kinase PfkB family
HB762_17560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB762_17560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB762_17560	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HB762_17575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB762_17580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB762_17590	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HB762_17600	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HB762_17620	COG0697	spore germination
HB762_17630	COG1028	Short-chain dehydrogenase reductase Sdr
HB762_17655	COG2801	Transposase and inactivated derivatives
HB762_17685	COG1335	isochorismatase
HB762_17690	COG0284	orotidine-5'-phosphate decarboxylase activity
HB762_17710	COG2801	Transposase and inactivated derivatives
HB762_17770	COG1335	isochorismatase
HB762_17940	COG3005	denitrification pathway
HB762_17985	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HB762_17990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB762_17995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB762_18000	COG1120	ATPase activity
HB762_18085	COG0583	DNA-binding transcription factor activity
HB762_18105	COG5640	endopeptidase activity
HB762_18110	COG1132	(ABC) transporter
HB762_18140	COG2816	NAD+ diphosphatase activity
HB762_18155	COG2814	Major facilitator Superfamily
HB762_18250	COG0739	heme binding
HB762_18305	COG0814	amino acid
HB762_18375	COG1785	Belongs to the alkaline phosphatase family
HB762_18400	COG0443	Heat shock 70 kDa protein
HB762_18445	COG2200	EAL domain
HB762_18450	COG5002	protein histidine kinase activity
HB762_18485	COG4160	amino acid transport
HB762_18490	COG4215	(ABC) transporter
HB762_18495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB762_18500	COG1126	abc transporter atp-binding protein
HB762_18535	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB762_18545	COG1012	belongs to the aldehyde dehydrogenase family
HB762_18560	COG1902	pentaerythritol trinitrate reductase activity
HB762_18560	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB762_18570	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HB762_18575	COG1845	cytochrome c oxidase, subunit III
HB762_18580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HB762_18585	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HB762_18590	COG1028	Short-chain dehydrogenase reductase Sdr
HB762_18600	COG1024	Enoyl-CoA hydratase
HB762_18605	COG1024	Enoyl-CoA hydratase
HB762_18620	COG0183	Belongs to the thiolase family
HB762_18630	COG1960	acyl-CoA dehydrogenase activity
HB762_18635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HB762_18640	COG1024	Enoyl-CoA hydratase
HB762_18680	COG3278	Belongs to the heme-copper respiratory oxidase family
HB762_18695	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HB762_18700	COG5001	Diguanylate cyclase
HB762_18705	COG0513	Belongs to the DEAD box helicase family
HB762_18710	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
HB762_18725	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HB762_18740	COG1119	ATPase activity
HB762_18745	COG2200	EAL domain
HB762_18765	COG0513	Belongs to the DEAD box helicase family
HB762_18770	COG3447	MASE1 domain protein
HB762_18770	COG5001	Diguanylate cyclase
HB762_18770	COG5002	protein histidine kinase activity
HB762_18775	COG0523	cobalamin synthesis protein
HB762_18810	COG0454	-acetyltransferase
HB762_18820	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HB762_18825	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HB762_18830	COG1845	cytochrome c oxidase, subunit III
HB762_18835	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HB762_18860	COG3530	Putative quorum-sensing-regulated virulence factor
HB762_18885	COG3186	Phenylalanine-4-hydroxylase
HB762_18890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HB762_18895	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB762_18920	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HB762_18925	COG1454	alcohol dehydrogenase
HB762_18930	COG2133	pyrroloquinoline quinone binding
HB762_18935	COG1619	proteins homologs of microcin C7 resistance protein MccF
HB762_18945	COG0783	Belongs to the Dps family
HB762_18960	COG1136	(ABC) transporter
HB762_18980	COG2199	diguanylate cyclase activity
HB762_18990	COG3036	rescue of stalled ribosome
HB762_18995	COG1278	Cold shock
HB762_19025	COG0545	Peptidyl-prolyl cis-trans isomerase
HB762_19030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB762_19040	COG0840	transmembrane signaling receptor activity
HB762_19065	COG2197	response regulator
HB762_19070	COG3850	Histidine kinase
HB762_19075	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB762_19095	COG3005	denitrification pathway
HB762_19115	COG0183	Belongs to the thiolase family
HB762_19125	COG1280	lysine exporter protein (LysE YggA)
HB762_19135	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB762_19140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB762_19220	COG0673	inositol 2-dehydrogenase activity
HB762_19245	COG0583	DNA-binding transcription factor activity
HB762_19255	COG1522	sequence-specific DNA binding
HB762_19260	COG0531	amino acid
HB762_19275	COG2205	protein histidine kinase activity
HB762_19280	COG0745	RESPONSE REGULATOR receiver
HB762_19305	COG1566	PFAM secretion protein HlyD family protein
HB762_19310	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HB762_19315	COG2239	Acts as a magnesium transporter
HB762_19320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HB762_19325	COG0402	S-adenosylhomocysteine deaminase activity
HB762_19340	COG1418	mRNA catabolic process
HB762_19355	COG2814	Major facilitator Superfamily
HB762_19365	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HB762_19385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB762_19400	COG4221	oxidoreductase activity
HB762_19405	COG0745	RESPONSE REGULATOR receiver
HB762_19410	COG2205	protein histidine kinase activity
HB762_19420	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HB762_19425	COG2194	sulfuric ester hydrolase activity
HB762_19430	COG0673	inositol 2-dehydrogenase activity
HB762_19435	COG4977	sequence-specific DNA binding
HB762_19445	COG2814	Major facilitator Superfamily
HB762_19455	COG2249	NAD(P)H dehydrogenase (quinone) activity
HB762_19470	COG0583	DNA-binding transcription factor activity
HB762_19505	COG0366	Alpha amylase catalytic
HB762_19510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB762_19515	COG0835	chemotaxis
HB762_19515	COG0784	Response regulator, receiver
HB762_19525	COG0748	coenzyme F420 binding
HB762_19530	COG3721	Heme iron utilization protein
HB762_19540	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HB762_19545	COG0811	peptide transport
HB762_19550	COG0848	biopolymer transport protein
HB762_19560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB762_19565	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HB762_19605	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HB762_19615	COG0633	Ferredoxin
HB762_19615	COG3217	Mosc domain protein beta barrel domain protein
HB762_19615	COG0633	Ferredoxin
HB762_19615	COG3217	Mosc domain protein beta barrel domain protein
HB762_19620	COG0401	homolog of Blt101
HB762_19630	COG2354	Protein conserved in bacteria
HB762_19660	COG3833	ABC-type maltose transport systems, permease component
HB762_19665	COG1175	transmembrane transport
HB762_19675	COG3842	ATPase activity
HB762_19680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HB762_19695	COG0489	protein tyrosine kinase activity
HB762_19695	COG3206	protein involved in exopolysaccharide biosynthesis
HB762_19740	COG1309	transcriptional regulator
HB762_19745	COG2130	NADP-dependent
HB762_19755	COG0753	catalase activity
HB762_19760	COG2084	Dehydrogenase
HB762_19775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB762_19775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB762_19775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB762_19800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB762_19805	COG1301	dicarboxylic acid transport
HB762_19810	COG1252	NADH dehydrogenase
HB762_19835	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
HB762_19875	COG3852	Histidine kinase
HB762_19880	COG2204	response regulator
HB762_19905	COG2197	response regulator
HB762_19915	COG0840	transmembrane signaling receptor activity
HB762_19925	COG0714	Associated with various cellular activities
HB762_19945	COG2304	oxidoreductase activity
HB762_19960	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HB762_19965	COG0581	inorganic phosphate transmembrane transporter activity
HB762_19970	COG0573	inorganic phosphate transmembrane transporter activity
HB762_19980	COG0840	transmembrane signaling receptor activity
HB762_20005	COG1770	oligopeptidase
HB762_20015	COG0513	Belongs to the DEAD box helicase family
HB762_20035	COG1280	lysine exporter protein (LysE YggA)
HB762_20100	COG0584	glycerophosphoryl diester phosphodiesterase
HB762_20150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HB762_20200	COG4695	Portal protein
HB762_20290	COG0672	)-iron permease
HB762_20305	COG1376	ErfK ybiS ycfS ynhG family protein
HB762_20305	COG1388	LysM domain
HB762_20310	COG0415	Belongs to the DNA photolyase family
HB762_20315	COG0789	Transcriptional regulator
HB762_20320	COG3272	Protein of unknown function (DUF1722)
HB762_20325	COG0813	purine-nucleoside phosphorylase activity
HB762_20355	COG1566	PFAM secretion protein HlyD family protein
HB762_20365	COG1122	ATPase activity
HB762_20385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB762_20405	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HB762_20415	COG1067	ATP-dependent peptidase activity
HB762_20425	COG4172	Belongs to the ABC transporter superfamily
HB762_20430	COG1505	serine-type exopeptidase activity
HB762_20435	COG0583	DNA-binding transcription factor activity
HB762_20440	COG1620	l-lactate permease
HB762_20450	COG1304	FMN binding
HB762_20460	COG0668	transmembrane transport
HB762_20470	COG1063	alcohol dehydrogenase
HB762_20475	COG2223	nitrite transmembrane transporter activity
HB762_20480	COG2199	diguanylate cyclase activity
HB762_20480	COG2203	Gaf domain
HB762_20505	COG1063	alcohol dehydrogenase
HB762_20560	COG0584	glycerophosphoryl diester phosphodiesterase
HB762_20660	COG4695	Portal protein
HB762_20780	COG4974	Belongs to the 'phage' integrase family
HB762_20785	COG1063	alcohol dehydrogenase
HB762_20790	COG0156	8-amino-7-oxononanoate synthase activity
HB762_20825	COG0346	lactoylglutathione lyase activity
HB762_20925	COG1987	bacterial-type flagellum assembly
HB762_20935	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HB762_20950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB762_20960	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HB762_20980	COG1580	Controls the rotational direction of flagella during chemotaxis
HB762_20985	COG1191	sigma factor activity
HB762_20990	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HB762_20995	COG1360	Flagellar Motor Protein
HB762_21005	COG0384	phenazine biosynthesis protein PhzF
HB762_21075	COG1256	bacterial-type flagellum assembly
HB762_21075	COG4786	Flagellar basal body rod
HB762_21085	COG1706	bacterial-type flagellum-dependent cell motility
HB762_21090	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HB762_21095	COG4786	Flagellar basal body rod
HB762_21100	COG4787	bacterial-type flagellum-dependent cell motility
HB762_21105	COG1749	Flagellar hook protein flgE
HB762_21110	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HB762_21115	COG1558	bacterial-type flagellum-dependent cell motility
HB762_21120	COG1815	bacterial-type flagellum-dependent cell motility
HB762_21140	COG0741	lytic transglycosylase activity
HB762_21140	COG1388	LysM domain
HB762_21170	COG1760	l-serine dehydratase
HB762_21175	COG3104	oligopeptide transport
HB762_21200	COG0583	DNA-binding transcription factor activity
HB762_21210	COG2866	Carboxypeptidase
HB762_21215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB762_21225	COG2990	Protein conserved in bacteria
HB762_21250	COG3842	ATPase activity
HB762_21255	COG1840	ABC-type Fe3 transport system, periplasmic component
HB762_21265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HB762_21285	COG3240	lipase activity
HB762_21310	COG1011	Hydrolase
HB762_21350	COG1765	OsmC-like protein
HB762_21355	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB762_21355	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB762_21370	COG3046	protein related to deoxyribodipyrimidine photolyase
HB762_21375	COG0415	Belongs to the DNA photolyase family
HB762_21380	COG3706	GGDEF domain
HB762_21415	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HB762_21420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB762_21440	COG3033	Beta-eliminating lyase
HB762_21455	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HB762_21460	COG0579	oxidoreductase
HB762_21475	COG1114	Component of the transport system for branched-chain amino acids
HB762_21490	COG2723	6-phospho-beta-galactosidase activity
HB762_21515	COG0583	DNA-binding transcription factor activity
HB762_21535	COG0189	ligase activity
HB762_21540	COG4067	protein conserved in archaea
HB762_21540	COG0189	ligase activity
HB762_21555	COG0010	Belongs to the arginase family
HB762_21560	COG2814	Major facilitator Superfamily
HB762_21565	COG1770	oligopeptidase
HB762_21580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB762_21585	COG1121	(ABC) transporter
HB762_21635	COG0848	biopolymer transport protein
HB762_21640	COG0811	peptide transport
HB762_21645	COG0811	peptide transport
HB762_21665	COG0745	RESPONSE REGULATOR receiver
HB762_21670	COG0584	glycerophosphoryl diester phosphodiesterase
HB762_21680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HB762_21740	COG0312	modulator of DNA gyrase
HB762_21750	COG0351	phosphomethylpyrimidine kinase
HB762_21755	COG1116	anion transmembrane transporter activity
HB762_21760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB762_21765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB762_21770	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HB762_21775	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HB762_21785	COG0671	phosphoesterase, PA-phosphatase related
HB762_21805	COG1028	Short-chain dehydrogenase reductase Sdr
HB762_21855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB762_21870	COG0477	Major facilitator Superfamily
HB762_21875	COG1929	Belongs to the glycerate kinase type-1 family
HB762_21880	COG3835	regulator
HB762_21925	COG0668	transmembrane transport
HB762_22015	COG3047	cAMP biosynthetic process
HB762_22020	COG1357	PFAM Pentapeptide repeats (8 copies)
HB762_22030	COG2076	Multidrug Resistance protein
HB762_22075	COG0583	DNA-binding transcription factor activity
HB762_22090	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HB762_22100	COG3152	Membrane
HB762_22120	COG0561	phosphatase activity
HB762_22125	COG0564	pseudouridine synthase activity
HB762_22135	COG1609	Transcriptional regulator
HB762_22140	COG3842	ATPase activity
HB762_22145	COG2723	6-phospho-beta-galactosidase activity
HB762_22150	COG0395	ABC-type sugar transport system, permease component
HB762_22165	COG1609	Transcriptional regulator
HB762_22175	COG5001	Diguanylate cyclase
HB762_22235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HB762_22240	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HB762_22250	COG2259	Doxx family
HB762_22285	COG3623	hexulose-6-phosphate isomerase
HB762_22290	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HB762_22295	COG0561	phosphatase activity
HB762_22330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB762_22335	COG1131	(ABC) transporter
HB762_22345	COG2897	thiosulfate sulfurtransferase activity
HB762_22360	COG0583	DNA-binding transcription factor activity
HB762_22410	COG1028	Short-chain dehydrogenase reductase Sdr
HB762_22415	COG0786	glutamate:sodium symporter activity
HB762_22435	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HB762_22445	COG3279	Response regulator of the LytR AlgR family
HB762_22450	COG3275	phosphorelay sensor kinase activity
HB762_22505	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
HB762_22505	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HB762_22515	COG0444	Belongs to the ABC transporter superfamily
HB762_22520	COG4608	Belongs to the ABC transporter superfamily
HB762_22545	COG1444	tRNA N-acetyltransferase activity
HB762_22550	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HB762_22555	COG0848	biopolymer transport protein
HB762_22595	COG1595	DNA-templated transcription, initiation
HB762_22625	COG4166	transmembrane transport
HB762_22750	COG1132	(ABC) transporter
HB762_22770	COG0667	Aldo Keto reductase
HB762_22775	COG0513	Belongs to the DEAD box helicase family
HB762_22780	COG3713	MltA-interacting MipA family protein
HB762_22790	COG2153	protein acetylation
HB762_22795	COG2258	MOSC domain
HB762_22805	COG2207	Transcriptional regulator
HB762_22810	COG0544	peptidyl-prolyl cis-trans isomerase activity
HB762_22815	COG0544	peptidyl-prolyl cis-trans isomerase activity
HB762_22820	COG1522	sequence-specific DNA binding
HB762_22850	COG1349	DNA-binding transcription factor activity
HB762_22855	COG2084	Dehydrogenase
HB762_22860	COG3395	kinase activity
HB762_22865	COG0235	Class ii aldolase
HB762_22870	COG3622	Belongs to the hyi family
HB762_22875	COG2610	gluconate transmembrane transporter activity
HB762_22885	COG3634	alkyl hydroperoxide reductase activity
HB762_22905	COG1846	Transcriptional regulator
HB762_22910	COG1764	response to oxidative stress
HB762_22945	COG0577	efflux transmembrane transporter activity
HB762_22950	COG1136	(ABC) transporter
HB762_22955	COG1335	isochorismatase
HB762_22975	COG0840	transmembrane signaling receptor activity
HB762_22980	COG0612	Peptidase, M16
HB762_23010	COG3188	usher protein
HB762_23015	COG3121	Chaperone
HB762_23050	COG0739	heme binding
HB762_23105	COG2356	endonuclease I
HB762_23155	COG4589	Belongs to the CDS family
HB762_23175	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HB762_23180	COG1162	GTPase activity
HB762_23185	COG1263	PTS System
HB762_23185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB762_23195	COG1999	signal sequence binding
HB762_23215	COG0058	SHG alpha-glucan phosphorylase activity
HB762_23220	COG1640	4-alpha-glucanotransferase
HB762_23225	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HB762_23230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HB762_23235	COG0366	Alpha amylase catalytic
HB762_23250	COG2207	Transcriptional regulator
HB762_23265	COG3339	Conserved Protein
HB762_23270	COG1301	dicarboxylic acid transport
HB762_23290	COG0489	protein tyrosine kinase activity
HB762_23290	COG3206	protein involved in exopolysaccharide biosynthesis
HB762_23300	COG1596	polysaccharide export
HB762_23315	COG4667	esterase of the alpha-beta hydrolase superfamily
HB762_23325	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HB762_23330	COG0415	Belongs to the DNA photolyase family
HB762_23345	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB762_23350	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB762_23370	COG1686	Belongs to the peptidase S11 family
HB762_23380	COG0583	DNA-binding transcription factor activity
HB762_23385	COG4628	conserved protein (DUF2132)
HB762_23395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB762_23410	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HB762_23415	COG0628	permease
HB762_23425	COG2988	succinylglutamate desuccinylase activity
HB762_23435	COG2814	Major facilitator Superfamily
HB762_23445	COG0454	-acetyltransferase
HB762_23455	COG0745	RESPONSE REGULATOR receiver
HB762_23460	COG2205	protein histidine kinase activity
HB762_23480	COG0384	phenazine biosynthesis protein PhzF
HB762_23485	COG0346	lactoylglutathione lyase activity
HB762_23500	COG0488	(ABC) transporter
HB762_23505	COG4628	conserved protein (DUF2132)
HB762_23510	COG0583	DNA-binding transcription factor activity
HB762_23515	COG0431	NADPH-dependent FMN reductase
HB762_23520	COG0435	Glutathione S-transferase
HB762_23525	COG0488	(ABC) transporter
HB762_23540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HB762_23545	COG1280	lysine exporter protein (LysE YggA)
HB762_23580	COG0346	lactoylglutathione lyase activity
HB762_23585	COG1349	DNA-binding transcription factor activity
HB762_23600	COG1335	isochorismatase
HB762_23625	COG3136	membrane protein required for alginate biosynthesis
HB762_23635	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HB762_23645	COG0583	DNA-binding transcription factor activity
HB762_23660	COG3448	diguanylate cyclase activity
HB762_23660	COG4175	Glycine betaine
HB762_23665	COG4176	ABC-type proline glycine betaine transport system permease component
HB762_23705	COG4948	Mandelate Racemase Muconate Lactonizing
HB762_23755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB762_23785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB762_23820	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HB762_23830	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HB762_23855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HB762_23855	COG0574	Belongs to the PEP-utilizing enzyme family
HB762_23865	COG2807	transmembrane transport
HB762_23870	COG2207	Transcriptional regulator
HB762_23880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HB762_23885	COG0583	DNA-binding transcription factor activity
HB762_23895	COG1215	transferase activity, transferring glycosyl groups
HB762_23900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HB762_23910	COG2321	neutral zinc metallopeptidase
HB762_23915	COG3122	Protein conserved in bacteria
HB762_23930	COG2255	four-way junction helicase activity
HB762_23940	COG3853	Toxic anion resistance protein (TelA)
HB762_23965	COG0583	DNA-binding transcription factor activity
HB762_23975	COG3675	Pfam Lipase (class 3)
HB762_24020	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HB762_24020	COG0515	serine threonine protein kinase
HB762_24025	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HB762_24030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HB762_24035	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HB762_24040	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HB762_24070	COG0513	Belongs to the DEAD box helicase family
HB762_24110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB762_24130	COG3746	phosphate-selective porin O and P
HB762_24155	COG1028	Short-chain dehydrogenase reductase Sdr
HB762_24175	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HB762_24175	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HB762_24190	COG0625	glutathione transferase activity
HB762_24370	COG0625	glutathione transferase activity
HB762_24395	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HB762_24410	COG2801	Transposase and inactivated derivatives
HB762_24450	COG2801	Transposase and inactivated derivatives
HB762_24465	COG1683	Conserved Protein
HB762_24535	COG0583	DNA-binding transcription factor activity
HB762_24565	COG3483	tryptophan 2,3-dioxygenase activity
HB762_24570	COG1028	Short-chain dehydrogenase reductase Sdr
HB762_24585	COG0823	Involved in the tonB-independent uptake of proteins
HB762_24590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB762_24595	COG2084	Dehydrogenase
HB762_24600	COG1764	response to oxidative stress
HB762_24655	COG0625	glutathione transferase activity
HB762_24660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB762_24665	COG1686	Belongs to the peptidase S11 family
HB762_24675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB762_24685	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HB762_24700	COG1278	Cold shock
HB762_24705	COG1741	Belongs to the pirin family
HB762_24710	COG4667	esterase of the alpha-beta hydrolase superfamily
HB762_24720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HB762_24730	COG0523	cobalamin synthesis protein
HB762_24755	COG3842	ATPase activity
HB762_24760	COG0395	ABC-type sugar transport system, permease component
HB762_24765	COG1175	transmembrane transport
HB762_24775	COG0584	glycerophosphoryl diester phosphodiesterase
HB762_24785	COG0589	response to stress
HB762_24795	COG0488	(ABC) transporter
HB762_24800	COG1505	serine-type exopeptidase activity
HB762_24830	COG1858	cytochrome C peroxidase
HB762_24845	COG0494	nUDIX hydrolase
HB762_24860	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HB762_24870	COG0714	Associated with various cellular activities
HB762_24905	COG0583	DNA-binding transcription factor activity
HB762_24910	COG1280	lysine exporter protein (LysE YggA)
HB762_24920	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB762_24955	COG0842	Transport permease protein
HB762_24960	COG1131	(ABC) transporter
HB762_24975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB762_24980	COG0800	Aldolase
HB762_24990	COG2706	6-phosphogluconolactonase activity
HB762_24995	COG0251	oxidation-reduction process
HB762_25005	COG1881	PFAM PEBP family protein
HB762_25020	COG0798	PFAM Bile acid sodium symporter
HB762_25040	COG2814	Major facilitator Superfamily
HB762_25045	COG1120	ATPase activity
HB762_25050	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HB762_25085	COG0814	amino acid
HB762_25100	COG3314	Sporulation integral membrane protein YlbJ
HB762_25120	COG0739	heme binding
HB762_25125	COG5001	Diguanylate cyclase
HB762_25130	COG1120	ATPase activity
HB762_25160	COG0583	DNA-binding transcription factor activity
HB762_25165	COG2814	Major facilitator Superfamily
HB762_25180	COG0697	spore germination
HB762_25195	COG0179	Fumarylacetoacetate (FAA) hydrolase
HB762_25215	COG1280	lysine exporter protein (LysE YggA)
HB762_25225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HB762_25265	COG1612	heme a metabolic process
HB762_25280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB762_25290	COG0840	transmembrane signaling receptor activity
HB762_25295	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HB762_25315	COG2897	thiosulfate sulfurtransferase activity
HB762_25350	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HB762_25355	COG0303	'Molybdopterin
HB762_25385	COG4989	oxidoreductase activity
HB762_25400	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HB762_25400	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HB762_25455	COG0583	DNA-binding transcription factor activity
HB762_25475	COG4964	Belongs to the GSP D family
HB762_25485	COG0455	bacterial-type flagellum organization
HB762_25525	COG2885	chlorophyll binding
HB762_25565	COG4175	Glycine betaine
HB762_25565	COG0517	IMP dehydrogenase activity
HB762_25575	COG0330	HflC and HflK could
HB762_25600	COG0784	Response regulator, receiver
HB762_25600	COG2205	protein histidine kinase activity
HB762_25660	COG5001	Diguanylate cyclase
HB762_25670	COG1129	ABC transporter
HB762_25675	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB762_25680	COG1879	ABC-type sugar transport system periplasmic component
HB762_25685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB762_25690	COG1609	Transcriptional regulator
HB762_25705	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HB762_25720	COG4607	ABC-type enterochelin transport system periplasmic component
HB762_25725	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB762_25730	COG4605	iron ion homeostasis
HB762_25735	COG4604	ABC transporter, ATP-binding protein
HB762_25740	COG0789	Transcriptional regulator
HB762_25765	COG1289	transmembrane transporter activity
HB762_25770	COG0210	DNA helicase
HB762_25780	COG1879	ABC-type sugar transport system periplasmic component
HB762_25785	COG2205	protein histidine kinase activity
HB762_25785	COG2198	Histidine kinase
HB762_25785	COG0784	Response regulator, receiver
HB762_25845	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HB762_25855	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HB762_25885	COG3069	C4-dicarboxylate transmembrane transporter activity
HB762_25915	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HB762_25930	COG0739	heme binding
HB762_26070	COG2204	response regulator
HB762_26095	COG3842	ATPase activity
HB762_26100	COG1609	Transcriptional regulator
HB762_26110	COG0564	pseudouridine synthase activity
HB762_26115	COG0561	phosphatase activity
HB762_26135	COG3152	Membrane
HB762_26145	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HB762_26240	COG0358	DNA primase activity
HB762_26350	COG2203	Gaf domain
HB762_26350	COG5001	Diguanylate cyclase
HB762_26350	COG4251	negative regulation of phosphorylation
HB762_26350	COG3706	GGDEF domain
HB762_26385	COG0330	HflC and HflK could
HB762_26390	COG0330	HflC and HflK could
HB762_26530	COG2200	EAL domain
HB762_26530	COG2199	diguanylate cyclase activity
HB762_26530	COG2203	Gaf domain
HB762_26800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB762_26855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HB762_26970	COG0358	DNA primase activity
HB762_27495	COG0358	DNA primase activity
HB762_27575	COG2337	Toxic component of a toxin-antitoxin (TA) module
HB762_27700	COG0270	DNA (cytosine-5-)-methyltransferase activity
HB762_27740	COG3081	Nucleoid-associated protein
HB762_27800	COG2974	May be involved in recombination
HB762_28050	COG2337	Toxic component of a toxin-antitoxin (TA) module
HB762_28170	COG0778	Nitroreductase
HB762_28225	COG3121	Chaperone
HB762_28395	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HB762_28400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HB762_28405	COG1192	Involved in chromosome partitioning
HB762_28530	COG4821	SIS domain
HB762_28575	COG0778	Nitroreductase
HB762_28630	COG3121	Chaperone