locus-tag	class	description
HB761_00090	COG4128	Pfam Zonular occludens toxin
HB761_00155	COG3278	Belongs to the heme-copper respiratory oxidase family
HB761_00170	COG2010	Cytochrome c
HB761_00180	COG2217	Heavy metal translocating P-type atpase
HB761_00195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB761_00200	COG0589	response to stress
HB761_00225	COG3842	ATPase activity
HB761_00235	COG1177	transmembrane transport
HB761_00245	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HB761_00250	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HB761_00265	COG0437	4 iron, 4 sulfur cluster binding
HB761_00270	COG0243	molybdopterin cofactor binding
HB761_00270	COG3383	formate dehydrogenase (NAD+) activity
HB761_00280	COG3381	protein complex oligomerization
HB761_00300	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HB761_00305	COG0488	(ABC) transporter
HB761_00320	COG4191	Histidine kinase
HB761_00325	COG2204	response regulator
HB761_00335	COG4662	Binding-protein-dependent transport system inner membrane component
HB761_00340	COG3842	ATPase activity
HB761_00350	COG0303	'Molybdopterin
HB761_00360	COG1940	carbohydrate kinase activity
HB761_00365	COG3148	PFAM DTW domain containing protein
HB761_00410	COG0840	transmembrane signaling receptor activity
HB761_00415	COG0791	NLP P60 protein
HB761_00425	COG3706	GGDEF domain
HB761_00430	COG2201	protein-glutamate methylesterase activity
HB761_00435	COG3001	Fructosamine kinase
HB761_00445	COG0307	riboflavin synthase, alpha
HB761_00450	COG0534	Mate efflux family protein
HB761_00460	COG1793	dna ligase
HB761_00470	COG2885	chlorophyll binding
HB761_00490	COG2204	response regulator
HB761_00495	COG0438	transferase activity, transferring glycosyl groups
HB761_00500	COG0438	transferase activity, transferring glycosyl groups
HB761_00530	COG0438	transferase activity, transferring glycosyl groups
HB761_00535	COG1215	transferase activity, transferring glycosyl groups
HB761_00540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HB761_00565	COG3300	MHYT domain
HB761_00565	COG5001	Diguanylate cyclase
HB761_00570	COG4999	Histidine kinase
HB761_00570	COG3850	Histidine kinase
HB761_00570	COG3437	response regulator, receiver
HB761_00570	COG2205	protein histidine kinase activity
HB761_00595	COG0784	Response regulator, receiver
HB761_00595	COG2205	protein histidine kinase activity
HB761_00615	COG1846	Transcriptional regulator
HB761_00630	COG3247	response to pH
HB761_00635	COG0668	transmembrane transport
HB761_00650	COG0318	PFAM AMP-dependent synthetase and ligase
HB761_00720	COG0625	glutathione transferase activity
HB761_00730	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HB761_00745	COG2195	Cleaves the N-terminal amino acid of tripeptides
HB761_00830	COG1451	nucleotide metabolic process
HB761_00840	COG0583	DNA-binding transcription factor activity
HB761_00870	COG4139	cobalamin transport
HB761_00885	COG2062	phosphohistidine phosphatase, SixA
HB761_00895	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HB761_00905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HB761_00910	COG0702	epimerase
HB761_00915	COG1823	symporter activity
HB761_00925	COG2925	Exonuclease
HB761_00935	COG1346	cytolysis
HB761_00985	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB761_00990	COG4605	iron ion homeostasis
HB761_00995	COG4607	ABC-type enterochelin transport system periplasmic component
HB761_01000	COG4774	siderophore transport
HB761_01020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB761_01035	COG1132	(ABC) transporter
HB761_01040	COG1535	isochorismatase
HB761_01040	COG3433	isochorismatase activity
HB761_01045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HB761_01045	COG0072	phenylalanine-tRNA ligase activity
HB761_01095	COG0251	oxidation-reduction process
HB761_01120	COG3119	arylsulfatase activity
HB761_01125	COG0641	radical SAM
HB761_01160	COG2188	Transcriptional regulator
HB761_01170	COG0010	Belongs to the arginase family
HB761_01180	COG2986	histidine ammonia-lyase
HB761_01225	COG0277	FAD linked oxidase domain protein
HB761_01225	COG0247	lactate metabolic process
HB761_01270	COG3620	sequence-specific DNA binding
HB761_01345	COG1643	Atp-dependent helicase
HB761_01355	COG2949	membrane
HB761_01360	COG0471	metal ion transport
HB761_01380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HB761_01385	COG0492	ferredoxin-NADP+ reductase activity
HB761_01390	COG4988	ABC transporter
HB761_01395	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HB761_01420	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HB761_01430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB761_01430	COG4191	Histidine kinase
HB761_01445	COG3070	regulator of competence-specific genes
HB761_01455	COG2431	L-lysine efflux transmembrane transporter activity
HB761_01465	COG0076	glutamate decarboxylase activity
HB761_01470	COG1737	Transcriptional regulator
HB761_01480	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HB761_01490	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HB761_01525	COG0534	Mate efflux family protein
HB761_01530	COG0702	epimerase
HB761_01540	COG2814	Major facilitator Superfamily
HB761_01545	COG1187	pseudouridine synthase activity
HB761_01550	COG1061	Type III restriction enzyme res subunit
HB761_01605	COG3313	Fe-S protein
HB761_01615	COG0659	secondary active sulfate transmembrane transporter activity
HB761_01625	COG4134	Bacterial extracellular solute-binding protein
HB761_01630	COG4135	transport system, permease component
HB761_01635	COG4136	ATPase activity
HB761_01640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HB761_01650	COG2814	Major facilitator Superfamily
HB761_01670	COG0564	pseudouridine synthase activity
HB761_01675	COG0733	neurotransmitter:sodium symporter activity
HB761_01685	COG0626	cystathionine gamma-synthase activity
HB761_01690	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HB761_01710	COG2818	Glycosylase
HB761_01720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB761_01730	COG1983	PspC domain protein
HB761_01740	COG1842	Phage shock protein A
HB761_01745	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HB761_01755	COG4168	peptide transport system, permease
HB761_01760	COG4171	peptide transport system, permease
HB761_01770	COG4172	Belongs to the ABC transporter superfamily
HB761_01780	COG1227	inorganic diphosphatase activity
HB761_01785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB761_01790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB761_01795	COG1121	(ABC) transporter
HB761_01810	COG0243	molybdopterin cofactor binding
HB761_01815	COG3005	denitrification pathway
HB761_01820	COG4459	periplasmic nitrate reductase
HB761_01825	COG0390	transport system, permease component
HB761_01835	COG2116	formate transmembrane transporter activity
HB761_01855	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HB761_01860	COG1435	thymidine kinase activity
HB761_01865	COG0215	cysteine-tRNA ligase activity
HB761_01870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HB761_01875	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HB761_01880	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HB761_01885	COG3012	SEC-C Motif Domain Protein
HB761_01890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HB761_01890	COG0140	phosphoribosyl-ATP diphosphatase activity
HB761_01900	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HB761_01905	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HB761_01910	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HB761_01910	COG0131	Imidazoleglycerol-phosphate dehydratase
HB761_01920	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HB761_01930	COG1757	Na H antiporter
HB761_01940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB761_01960	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HB761_01980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HB761_01995	COG0300	oxidoreductase activity
HB761_02020	COG2226	methyltransferase
HB761_02040	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HB761_02050	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HB761_02060	COG1674	ftsk spoiiie
HB761_02070	COG0686	Belongs to the AlaDH PNT family
HB761_02080	COG0583	DNA-binding transcription factor activity
HB761_02105	COG0402	S-adenosylhomocysteine deaminase activity
HB761_02110	COG4934	collagen metabolic process
HB761_02125	COG3568	Endonuclease Exonuclease Phosphatase
HB761_02145	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HB761_02160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB761_02165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB761_02180	COG0534	Mate efflux family protein
HB761_02190	COG1629	transport
HB761_02190	COG4774	siderophore transport
HB761_02200	COG2824	Alkylphosphonate utilization operon protein PhnA
HB761_02245	COG0457	Tetratricopeptide repeat
HB761_02315	COG4790	Type iii secretion
HB761_02320	COG4794	Type iii secretion
HB761_02325	COG4791	protein targeting
HB761_02330	COG4792	protein secretion
HB761_02335	COG0583	DNA-binding transcription factor activity
HB761_02345	COG3177	Filamentation induced by cAMP protein fic
HB761_02375	COG4669	(LipO)protein
HB761_02460	COG0456	acetyltransferase
HB761_02470	COG0534	Mate efflux family protein
HB761_02510	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HB761_02570	COG0784	Response regulator, receiver
HB761_02570	COG2205	protein histidine kinase activity
HB761_02580	COG0754	glutathionylspermidine amidase activity
HB761_02590	COG3766	membrane
HB761_02605	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HB761_02610	COG2885	chlorophyll binding
HB761_02615	COG0823	Involved in the tonB-independent uptake of proteins
HB761_02630	COG0811	peptide transport
HB761_02635	COG0824	Thioesterase
HB761_02645	COG4890	Cyd operon protein YbgT
HB761_02650	COG1294	oxidase, subunit
HB761_02655	COG1271	oxidase subunit
HB761_02665	COG0632	four-way junction helicase activity
HB761_02670	COG0840	transmembrane signaling receptor activity
HB761_02685	COG1801	Protein of unknown function DUF72
HB761_02700	COG0189	ligase activity
HB761_02700	COG4067	protein conserved in archaea
HB761_02720	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HB761_02725	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HB761_02735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB761_02740	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HB761_02745	COG0745	RESPONSE REGULATOR receiver
HB761_02760	COG3070	regulator of competence-specific genes
HB761_02780	COG0297	glycogen (starch) synthase activity
HB761_02785	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HB761_02790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HB761_02820	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HB761_02825	COG0542	response to heat
HB761_02835	COG1278	Cold shock
HB761_02845	COG1187	pseudouridine synthase activity
HB761_02850	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HB761_02860	COG1199	ATP-dependent helicase activity
HB761_02865	COG0730	response to heat
HB761_02870	COG3923	Primosomal replication protein n
HB761_02880	COG0708	Exodeoxyribonuclease III
HB761_02915	COG1882	Formate acetyltransferase
HB761_02925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HB761_02940	COG2766	serine protein kinase
HB761_02945	COG2718	Belongs to the UPF0229 family
HB761_02950	COG2719	SpoVR family
HB761_02970	COG1132	(ABC) transporter
HB761_02975	COG0658	competence protein
HB761_02975	COG2333	competence protein COMEC
HB761_02985	COG4591	ABC-type transport system involved in lipoprotein release permease component
HB761_02990	COG1136	(ABC) transporter
HB761_02995	COG4591	ABC-type transport system involved in lipoprotein release permease component
HB761_03005	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HB761_03020	COG1252	NADH dehydrogenase
HB761_03050	COG0537	adenosine 5'-monophosphoramidase activity
HB761_03070	COG2217	Heavy metal translocating P-type atpase
HB761_03080	COG0516	GMP reductase activity
HB761_03080	COG0517	IMP dehydrogenase activity
HB761_03085	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
HB761_03090	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HB761_03095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB761_03105	COG3706	GGDEF domain
HB761_03120	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HB761_03125	COG1946	Acyl-CoA thioesterase
HB761_03130	COG1522	sequence-specific DNA binding
HB761_03150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB761_03205	COG2855	membrane
HB761_03215	COG0583	DNA-binding transcription factor activity
HB761_03220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB761_03220	COG2190	(PTS) system
HB761_03220	COG1263	PTS System
HB761_03235	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HB761_03240	COG0596	Alpha beta hydrolase
HB761_03250	COG1169	isochorismate synthase
HB761_03255	COG0436	Aminotransferase
HB761_03260	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HB761_03280	COG1555	photosystem II stabilization
HB761_03285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB761_03290	COG0776	regulation of translation
HB761_03295	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HB761_03335	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HB761_03340	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HB761_03345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HB761_03365	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HB761_03370	COG0569	domain protein
HB761_03375	COG0513	Belongs to the DEAD box helicase family
HB761_03385	COG4771	TonB-dependent receptor
HB761_03390	COG2977	Belongs to the P-Pant transferase superfamily
HB761_03400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB761_03400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB761_03405	COG3433	isochorismatase activity
HB761_03405	COG1535	isochorismatase
HB761_03410	COG1021	2,3-dihydroxybenzoate-AMP ligase
HB761_03415	COG1169	isochorismate synthase
HB761_03425	COG1028	Short-chain dehydrogenase reductase Sdr
HB761_03455	COG2852	Protein conserved in bacteria
HB761_03460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB761_03470	COG2951	lytic endotransglycosylase activity
HB761_03485	COG2894	cell division
HB761_03490	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HB761_03495	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HB761_03500	COG0318	PFAM AMP-dependent synthetase and ligase
HB761_03505	COG2267	carboxylic ester hydrolase activity
HB761_03510	COG3065	identical protein binding
HB761_03520	COG1214	PFAM Peptidase M22, glycoprotease
HB761_03525	COG1199	ATP-dependent helicase activity
HB761_03535	COG0788	formyltetrahydrofolate deformylase activity
HB761_03550	COG3102	Protein conserved in bacteria
HB761_03580	COG1918	ferrous iron import across plasma membrane
HB761_03585	COG4977	sequence-specific DNA binding
HB761_03590	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HB761_03595	COG1121	(ABC) transporter
HB761_03600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB761_03615	COG0508	dehydrogenase complex catalyzes the overall conversion of
HB761_03620	COG0567	Dehydrogenase, E1 component
HB761_03630	COG1053	succinate dehydrogenase
HB761_03635	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HB761_03650	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HB761_03660	COG0033	Phosphoglucomutase
HB761_03665	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HB761_03670	COG0596	Alpha beta hydrolase
HB761_03690	COG0735	belongs to the Fur family
HB761_03700	COG2190	(PTS) system
HB761_03700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB761_03700	COG1263	PTS System
HB761_03705	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HB761_03710	COG1940	carbohydrate kinase activity
HB761_03710	COG1846	Transcriptional regulator
HB761_03715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HB761_03715	COG4651	solute:proton antiporter activity
HB761_03720	COG0367	asparagine synthase
HB761_03725	COG0250	Participates in transcription elongation, termination and antitermination
HB761_03730	COG3104	oligopeptide transport
HB761_03735	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HB761_03750	COG3710	Transcriptional regulator
HB761_03770	COG0622	Phosphoesterase
HB761_03780	COG1090	epimerase
HB761_03785	COG0300	oxidoreductase activity
HB761_03790	COG3118	belongs to the thioredoxin family
HB761_03795	COG0330	HflC and HflK could
HB761_03825	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
HB761_03830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HB761_03835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB761_03840	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HB761_03845	COG2190	(PTS) system
HB761_03850	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB761_03855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB761_03860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB761_03880	COG1705	Flagellar rod assembly protein muramidase FlgJ
HB761_03880	COG3951	Flagellar rod assembly protein muramidase FlgJ
HB761_03885	COG1706	bacterial-type flagellum-dependent cell motility
HB761_03890	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HB761_03900	COG4787	bacterial-type flagellum-dependent cell motility
HB761_03910	COG1749	Flagellar hook protein flgE
HB761_03920	COG1558	bacterial-type flagellum-dependent cell motility
HB761_03925	COG1815	bacterial-type flagellum-dependent cell motility
HB761_03930	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HB761_03935	COG0835	chemotaxis
HB761_03935	COG0784	Response regulator, receiver
HB761_03990	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HB761_04000	COG2608	mercury ion transmembrane transporter activity
HB761_04000	COG2217	Heavy metal translocating P-type atpase
HB761_04040	COG2840	Smr protein MutS2
HB761_04045	COG1187	pseudouridine synthase activity
HB761_04050	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HB761_04055	COG0737	Belongs to the 5'-nucleotidase family
HB761_04065	COG2912	Transglutaminase-like superfamily
HB761_04075	COG2890	protein-(glutamine-N5) methyltransferase activity
HB761_04100	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HB761_04220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB761_04230	COG1702	phosphate starvation-inducible protein PhoH
HB761_04240	COG4535	Mg2 and Co2 transporter CorC
HB761_04245	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HB761_04250	COG2888	peptidyl-tyrosine sulfation
HB761_04260	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
HB761_04265	COG1466	dna polymerase III delta subunit
HB761_04270	COG0799	negative regulation of ribosome biogenesis
HB761_04280	COG0768	penicillin binding
HB761_04285	COG0772	Belongs to the SEDS family
HB761_04290	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HB761_04295	COG1686	Belongs to the peptidase S11 family
HB761_04315	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HB761_04320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HB761_04325	COG0366	Alpha amylase catalytic
HB761_04330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB761_04330	COG1263	PTS System
HB761_04340	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HB761_04345	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HB761_04350	COG2011	ABC-type metal ion transport system permease component
HB761_04355	COG1464	Belongs to the NlpA lipoprotein family
HB761_04365	COG0737	Belongs to the 5'-nucleotidase family
HB761_04370	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
HB761_04395	COG1611	Belongs to the LOG family
HB761_04415	COG2363	Small membrane protein
HB761_04425	COG0583	DNA-binding transcription factor activity
HB761_04440	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HB761_04450	COG0142	geranyltranstransferase activity
HB761_04460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HB761_04465	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HB761_04490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HB761_04490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HB761_04495	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HB761_04500	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HB761_04515	COG1073	alpha beta
HB761_04525	COG2252	PERMEase
HB761_04530	COG2195	Cleaves the N-terminal amino acid of tripeptides
HB761_04560	COG0047	phosphoribosylformylglycinamidine synthase activity
HB761_04560	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HB761_04570	COG0590	tRNA wobble adenosine to inosine editing
HB761_04575	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HB761_04595	COG4969	Belongs to the N-Me-Phe pilin family
HB761_04610	COG0443	Heat shock 70 kDa protein
HB761_04615	COG1301	dicarboxylic acid transport
HB761_04630	COG0497	DNA recombination
HB761_04635	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB761_04640	COG2914	Belongs to the UPF0125 (RnfH) family
HB761_04645	COG2867	negative regulation of translational initiation
HB761_04660	COG0583	DNA-binding transcription factor activity
HB761_04665	COG1289	transmembrane transporter activity
HB761_04685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HB761_04700	COG0668	transmembrane transport
HB761_04705	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HB761_04710	COG0583	DNA-binding transcription factor activity
HB761_04715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB761_04720	COG1115	amino acid carrier protein
HB761_04725	COG1584	GPR1 FUN34 yaaH family protein
HB761_04735	COG1757	Na H antiporter
HB761_04745	COG0517	IMP dehydrogenase activity
HB761_04745	COG0516	GMP reductase activity
HB761_04760	COG2199	diguanylate cyclase activity
HB761_04760	COG2203	Gaf domain
HB761_04775	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB761_04780	COG2976	Protein conserved in bacteria
HB761_04815	COG2975	iron-sulfur cluster assembly
HB761_04820	COG0633	Ferredoxin
HB761_04835	COG0316	Belongs to the HesB IscA family
HB761_04840	COG0822	iron-sulfur transferase activity
HB761_04855	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HB761_04860	COG0483	inositol monophosphate 1-phosphatase activity
HB761_04870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB761_04875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB761_04880	COG1862	Preprotein translocase
HB761_04900	COG0517	IMP dehydrogenase activity
HB761_04910	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HB761_04915	COG0583	DNA-binding transcription factor activity
HB761_04920	COG0450	alkyl hydroperoxide reductase
HB761_04935	COG0704	Plays a role in the regulation of phosphate uptake
HB761_04940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HB761_04945	COG0581	inorganic phosphate transmembrane transporter activity
HB761_04950	COG0573	inorganic phosphate transmembrane transporter activity
HB761_04955	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HB761_04960	COG0248	Ppx GppA phosphatase
HB761_04970	COG5002	protein histidine kinase activity
HB761_04975	COG0745	RESPONSE REGULATOR receiver
HB761_04985	COG0826	peptidase U32
HB761_04990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB761_05045	COG0542	response to heat
HB761_05055	COG0564	pseudouridine synthase activity
HB761_05060	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB761_05065	COG0741	lytic transglycosylase activity
HB761_05070	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HB761_05075	COG1605	Chorismate mutase
HB761_05075	COG0077	Prephenate dehydratase
HB761_05080	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
HB761_05095	COG0488	(ABC) transporter
HB761_05105	COG0739	heme binding
HB761_05110	COG0287	Prephenate dehydrogenase
HB761_05110	COG1605	Chorismate mutase
HB761_05115	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB761_05125	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HB761_05145	COG1966	Carbon starvation protein
HB761_05150	COG3275	phosphorelay sensor kinase activity
HB761_05155	COG3279	Response regulator of the LytR AlgR family
HB761_05160	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HB761_05165	COG1047	Peptidyl-prolyl cis-trans
HB761_05180	COG0196	riboflavin kinase activity
HB761_05185	COG0728	peptidoglycan biosynthetic process
HB761_05190	COG0268	Binds directly to 16S ribosomal RNA
HB761_05195	COG0640	Transcriptional regulator
HB761_05200	COG0583	DNA-binding transcription factor activity
HB761_05205	COG1283	sodium-dependent phosphate transmembrane transporter activity
HB761_05220	COG0730	response to heat
HB761_05245	COG0667	Aldo Keto reductase
HB761_05270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HB761_05275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB761_05280	COG4974	Belongs to the 'phage' integrase family
HB761_05285	COG0716	FMN binding
HB761_05300	COG0513	Belongs to the DEAD box helicase family
HB761_05310	COG3022	response to hydroperoxide
HB761_05315	COG1115	amino acid carrier protein
HB761_05345	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HB761_05350	COG0083	homoserine kinase activity
HB761_05365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HB761_05375	COG0745	RESPONSE REGULATOR receiver
HB761_05385	COG5002	protein histidine kinase activity
HB761_05385	COG2198	Histidine kinase
HB761_05385	COG0784	Response regulator, receiver
HB761_05390	COG4251	negative regulation of phosphorylation
HB761_05390	COG3706	GGDEF domain
HB761_05390	COG2203	Gaf domain
HB761_05390	COG5001	Diguanylate cyclase
HB761_05395	COG1242	4 iron, 4 sulfur cluster binding
HB761_05400	COG0069	glutamate synthase activity
HB761_05400	COG0067	glutamate synthase
HB761_05400	COG0070	glutamate synthase
HB761_05410	COG0070	glutamate synthase
HB761_05410	COG0069	glutamate synthase activity
HB761_05410	COG0067	glutamate synthase
HB761_05415	COG0493	'glutamate synthase
HB761_05440	COG2860	membrane
HB761_05445	COG0583	DNA-binding transcription factor activity
HB761_05450	COG0730	response to heat
HB761_05455	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HB761_05460	COG0505	Belongs to the CarA family
HB761_05470	COG0494	nUDIX hydrolase
HB761_05490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HB761_05495	COG0849	cell division
HB761_05500	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HB761_05515	COG0772	Belongs to the SEDS family
HB761_05530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HB761_05535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HB761_05540	COG0768	penicillin binding
HB761_05545	COG3116	cell division
HB761_05560	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HB761_05575	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HB761_05580	COG2823	Periplasmic or secreted lipoprotein
HB761_05585	COG2969	positive regulation of protein catabolic process
HB761_05590	COG0625	glutathione transferase activity
HB761_05595	COG2857	Cytochrome c1
HB761_05600	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HB761_05605	COG0723	plastoquinol--plastocyanin reductase activity
HB761_05620	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HB761_05625	COG3105	Protein conserved in bacteria
HB761_05630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HB761_05635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HB761_05640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HB761_05650	COG3150	esterase
HB761_05660	COG3151	Protein conserved in bacteria
HB761_05665	COG0494	nUDIX hydrolase
HB761_05670	COG1538	Outer membrane efflux protein
HB761_05680	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HB761_05690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HB761_05695	COG3025	triphosphatase activity
HB761_05700	COG1392	Phosphate transport regulator
HB761_05705	COG0306	phosphate transporter
HB761_05710	COG4991	sh3 domain protein
HB761_05720	COG3267	Type II secretory pathway component ExeA
HB761_05720	COG3409	Peptidoglycan-binding domain 1 protein
HB761_05735	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HB761_05740	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HB761_05750	COG0596	Alpha beta hydrolase
HB761_05755	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HB761_05760	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HB761_05765	COG1610	YqeY-like protein
HB761_05770	COG0358	DNA primase activity
HB761_05815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HB761_05820	COG1349	DNA-binding transcription factor activity
HB761_05825	COG0469	pyruvate kinase activity
HB761_05835	COG3706	GGDEF domain
HB761_05840	COG0440	acetolactate synthase activity
HB761_05845	COG0028	Belongs to the TPP enzyme family
HB761_05850	COG1022	Amp-dependent synthetase and ligase
HB761_05855	COG0583	DNA-binding transcription factor activity
HB761_05875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HB761_05880	COG0473	3-isopropylmalate dehydrogenase activity
HB761_05900	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HB761_05905	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HB761_05910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB761_05915	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HB761_05935	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HB761_05940	COG3610	response to peptide
HB761_05945	COG2966	Psort location CytoplasmicMembrane, score
HB761_05960	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HB761_05965	COG0142	geranyltranstransferase activity
HB761_05985	COG2358	TRAP transporter, solute receptor (TAXI family
HB761_06000	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HB761_06005	COG1178	ABC-type Fe3 transport system permease component
HB761_06010	COG4143	(ABC) transporter
HB761_06015	COG0163	prenyltransferase activity
HB761_06020	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HB761_06030	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HB761_06040	COG2105	PFAM AIG2 family protein
HB761_06055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB761_06065	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HB761_06080	COG1136	(ABC) transporter
HB761_06100	COG0529	Catalyzes the synthesis of activated sulfate
HB761_06105	COG3273	potassium ion transport
HB761_06105	COG0471	metal ion transport
HB761_06120	COG1648	precorrin-2 dehydrogenase activity
HB761_06120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HB761_06125	COG0737	Belongs to the 5'-nucleotidase family
HB761_06135	COG0513	Belongs to the DEAD box helicase family
HB761_06140	COG2153	protein acetylation
HB761_06155	COG0545	Peptidyl-prolyl cis-trans isomerase
HB761_06165	COG0203	ribosomal protein L17
HB761_06170	COG0202	RNA polymerase activity
HB761_06180	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HB761_06185	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HB761_06190	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HB761_06195	COG0201	protein transport
HB761_06205	COG1841	ribosomal large subunit assembly
HB761_06290	COG0088	Forms part of the polypeptide exit tunnel
HB761_06310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HB761_06315	COG1609	Transcriptional regulator
HB761_06335	COG1575	Belongs to the MenA family. Type 1 subfamily
HB761_06340	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HB761_06350	COG1494	fructose-1,6-bisphosphatase
HB761_06380	COG0149	triose-phosphate isomerase activity
HB761_06385	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HB761_06400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HB761_06405	COG0517	IMP dehydrogenase activity
HB761_06405	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HB761_06410	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HB761_06415	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HB761_06425	COG0463	Glycosyl transferase, family 2
HB761_06425	COG1216	Glycosyl transferase, family 2
HB761_06450	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HB761_06480	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB761_06490	COG1560	Kdo2-lipid A biosynthetic process
HB761_06500	COG0859	PFAM glycosyl transferase family 9
HB761_06505	COG1519	Transferase
HB761_06510	COG3273	potassium ion transport
HB761_06510	COG0471	metal ion transport
HB761_06515	COG0175	sulfate reduction
HB761_06520	COG0529	Catalyzes the synthesis of activated sulfate
HB761_06525	COG2895	sulfate adenylyltransferase (ATP) activity
HB761_06550	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HB761_06560	COG3642	lipopolysaccharide core region biosynthetic process
HB761_06565	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HB761_06570	COG0859	PFAM glycosyl transferase family 9
HB761_06575	COG0463	Glycosyl transferase, family 2
HB761_06590	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HB761_06610	COG2194	sulfuric ester hydrolase activity
HB761_06630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HB761_06640	COG1560	Kdo2-lipid A biosynthetic process
HB761_06645	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HB761_06650	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HB761_06655	COG1561	YicC-like family, N-terminal region
HB761_06665	COG2246	polysaccharide biosynthetic process
HB761_06680	COG4608	Belongs to the ABC transporter superfamily
HB761_06685	COG0444	Belongs to the ABC transporter superfamily
HB761_06690	COG0747	negative chemotaxis
HB761_06695	COG4239	(ABC) transporter, permease
HB761_06700	COG4174	ABC transporter (Permease)
HB761_06720	COG0811	peptide transport
HB761_06725	COG0848	biopolymer transport protein
HB761_06740	COG0194	GDP metabolic process
HB761_06745	COG1758	RNA polymerase activity
HB761_06750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HB761_06755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB761_06760	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HB761_06765	COG2233	PERMEase
HB761_06780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB761_06790	COG2183	response to ionizing radiation
HB761_06815	COG0494	nUDIX hydrolase
HB761_06820	COG1218	3'(2'),5'-bisphosphate nucleotidase
HB761_06830	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HB761_06835	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HB761_06840	COG3156	type II secretion system protein K
HB761_06845	COG4795	General secretion pathway protein
HB761_06850	COG2165	general secretion pathway protein
HB761_06855	COG2165	general secretion pathway protein
HB761_06860	COG2165	general secretion pathway protein
HB761_06865	COG1459	type II secretion system
HB761_06870	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB761_06880	COG3031	protein transport across the cell outer membrane
HB761_06885	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HB761_06905	COG0456	acetyltransferase
HB761_06910	COG1490	D-aminoacyl-tRNA deacylase activity
HB761_06930	COG1217	gtp-binding protein TYPA
HB761_06935	COG0174	glutamine synthetase
HB761_06945	COG3852	Histidine kinase
HB761_06950	COG2204	response regulator
HB761_06955	COG5001	Diguanylate cyclase
HB761_06955	COG3300	MHYT domain
HB761_06960	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HB761_06990	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HB761_06995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HB761_06995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HB761_07010	COG0084	hydrolase, TatD family'
HB761_07015	COG0805	protein transport
HB761_07020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HB761_07035	COG3165	ubiquinone biosynthetic process from chorismate
HB761_07045	COG1322	Protein conserved in bacteria
HB761_07060	COG1910	domain protein
HB761_07080	COG2081	HI0933 family
HB761_07090	COG1528	Iron-storage protein
HB761_07095	COG0589	response to stress
HB761_07115	COG5002	protein histidine kinase activity
HB761_07115	COG5001	Diguanylate cyclase
HB761_07120	COG1522	sequence-specific DNA binding
HB761_07130	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HB761_07140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB761_07145	COG0800	Aldolase
HB761_07160	COG0515	serine threonine protein kinase
HB761_07190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB761_07195	COG0601	transmembrane transport
HB761_07210	COG0546	phosphoglycolate phosphatase activity
HB761_07255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB761_07260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB761_07265	COG2960	long-chain fatty acid transporting porin activity
HB761_07270	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HB761_07275	COG0583	DNA-binding transcription factor activity
HB761_07320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HB761_07345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HB761_07350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HB761_07355	COG0551	DNA topoisomerase type I activity
HB761_07365	COG0758	DNA mediated transformation
HB761_07375	COG0242	peptide deformylase activity
HB761_07385	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HB761_07385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HB761_07390	COG0569	domain protein
HB761_07395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HB761_07405	COG1272	protein, Hemolysin III
HB761_07410	COG4326	sporulation control protein
HB761_07420	COG3084	Protein conserved in bacteria
HB761_07430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HB761_07435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB761_07440	COG0204	Acyl-transferase
HB761_07450	COG2199	diguanylate cyclase activity
HB761_07455	COG0606	chelatase, subunit chli
HB761_07465	COG3978	acetolactate synthase activity
HB761_07470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HB761_07475	COG0129	dihydroxy-acid dehydratase activity
HB761_07485	COG0583	DNA-binding transcription factor activity
HB761_07490	COG2814	Major facilitator Superfamily
HB761_07495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB761_07500	COG0765	amino acid transport
HB761_07510	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HB761_07520	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HB761_07550	COG3312	ion transport
HB761_07555	COG1475	DNA binding
HB761_07560	COG1192	Involved in chromosome partitioning
HB761_07575	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HB761_07605	COG1126	abc transporter atp-binding protein
HB761_07625	COG0592	DNA-directed DNA polymerase activity
HB761_07635	COG0187	DNA topoisomerase II activity
HB761_07640	COG0071	Belongs to the small heat shock protein (HSP20) family
HB761_07645	COG3977	Valine--pyruvate aminotransferase
HB761_07660	COG2119	membrane
HB761_07685	COG0604	alcohol dehydrogenase
HB761_07690	COG0183	Belongs to the thiolase family
HB761_07700	COG1739	Uncharacterized protein family UPF0029
HB761_07705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HB761_07750	COG2132	Multicopper oxidase
HB761_07770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HB761_07775	COG2104	thiamine diphosphate biosynthetic process
HB761_07790	COG0006	proline dipeptidase activity
HB761_07790	COG0006	proline dipeptidase activity
HB761_07800	COG2814	Major facilitator Superfamily
HB761_07820	COG3220	belongs to the UPF0276 family
HB761_07830	COG0210	DNA helicase
HB761_07835	COG0405	Gamma-glutamyltransferase
HB761_07840	COG1280	lysine exporter protein (LysE YggA)
HB761_07850	COG2962	Rard protein
HB761_07855	COG0514	ATP-dependent DNA helicase (RecQ)
HB761_07865	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HB761_07880	COG3118	belongs to the thioredoxin family
HB761_07895	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HB761_07900	COG0633	Ferredoxin
HB761_07940	COG3071	HemY protein
HB761_07945	COG2959	enzyme of heme biosynthesis
HB761_07950	COG1587	Uroporphyrinogen-III synthase
HB761_07960	COG3072	Adenylate cyclase
HB761_07975	COG0019	diaminopimelate decarboxylase activity
HB761_07995	COG1011	Hydrolase
HB761_08000	COG2199	diguanylate cyclase activity
HB761_08000	COG2200	EAL domain
HB761_08000	COG3287	FIST C domain
HB761_08005	COG3148	PFAM DTW domain containing protein
HB761_08020	COG0561	phosphatase activity
HB761_08025	COG2267	carboxylic ester hydrolase activity
HB761_08030	COG1280	lysine exporter protein (LysE YggA)
HB761_08035	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HB761_08040	COG0640	Transcriptional regulator
HB761_08045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HB761_08095	COG2095	MarC family integral membrane protein
HB761_08105	COG0742	ribosomal rna small subunit methyltransferase
HB761_08110	COG0552	protein localization to endoplasmic reticulum
HB761_08115	COG2884	Cell division ATP-binding protein ftsE
HB761_08120	COG2177	Part of the ABC transporter FtsEX involved in
HB761_08135	COG0705	Rhomboid family
HB761_08140	COG1580	Controls the rotational direction of flagella during chemotaxis
HB761_08145	COG3161	chorismate lyase activity
HB761_08155	COG2937	Belongs to the GPAT DAPAT family
HB761_08170	COG0534	Mate efflux family protein
HB761_08175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB761_08275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HB761_08285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HB761_08325	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HB761_08330	COG0250	Participates in transcription elongation, termination and antitermination
HB761_08345	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HB761_08365	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HB761_08370	COG2816	NAD+ diphosphatase activity
HB761_08380	COG1573	uracil-dna glycosylase
HB761_08390	COG3068	Protein conserved in bacteria
HB761_08395	COG1253	flavin adenine dinucleotide binding
HB761_08410	COG0151	Belongs to the GarS family
HB761_08425	COG0789	Transcriptional regulator
HB761_08430	COG3710	Transcriptional regulator
HB761_08435	COG0531	amino acid
HB761_08440	COG1982	Orn Lys Arg decarboxylase major
HB761_08485	COG2199	diguanylate cyclase activity
HB761_08490	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HB761_08495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HB761_08505	COG0439	Biotin carboxylase
HB761_08510	COG0511	ligase activity, forming carbon-carbon bonds
HB761_08515	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HB761_08520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HB761_08535	COG2814	Major facilitator Superfamily
HB761_08540	COG0784	Response regulator, receiver
HB761_08540	COG2198	Histidine kinase
HB761_08540	COG2205	protein histidine kinase activity
HB761_08560	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HB761_08570	COG2095	MarC family integral membrane protein
HB761_08580	COG4232	protein-disulfide reductase activity
HB761_08585	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HB761_08590	COG1027	Aspartate ammonia-lyase
HB761_08595	COG3030	protein affecting phage T7 exclusion by the F plasmid
HB761_08600	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HB761_08610	COG2205	protein histidine kinase activity
HB761_08615	COG0745	RESPONSE REGULATOR receiver
HB761_08625	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HB761_08635	COG0534	Mate efflux family protein
HB761_08665	COG1509	lysine 2,3-aminomutase activity
HB761_08695	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HB761_08700	COG1053	succinate dehydrogenase
HB761_08725	COG4942	peptidase
HB761_08730	COG1045	serine acetyltransferase
HB761_08745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HB761_08750	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HB761_08760	COG0840	transmembrane signaling receptor activity
HB761_08765	COG0471	metal ion transport
HB761_08775	COG1162	GTPase activity
HB761_08855	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HB761_08860	COG0802	atpase or kinase
HB761_08865	COG0860	N-Acetylmuramoyl-L-alanine amidase
HB761_08870	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HB761_08885	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HB761_08890	COG0330	HflC and HflK could
HB761_08895	COG0330	HflC and HflK could
HB761_08900	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HB761_08905	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HB761_08910	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HB761_08915	COG1017	nitric oxide dioxygenase activity
HB761_08915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB761_08925	COG0557	exoribonuclease II activity
HB761_08930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB761_08935	COG0546	phosphoglycolate phosphatase activity
HB761_08960	COG0512	Glutamine amidotransferase of anthranilate synthase
HB761_08965	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HB761_08985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB761_08990	COG3954	Phosphoribulokinase
HB761_09000	COG0429	hydrolase of the alpha beta-hydrolase fold
HB761_09010	COG0488	(ABC) transporter
HB761_09015	COG2249	NAD(P)H dehydrogenase (quinone) activity
HB761_09030	COG1047	Peptidyl-prolyl cis-trans
HB761_09035	COG1446	asparaginase
HB761_09050	COG0545	Peptidyl-prolyl cis-trans isomerase
HB761_09055	COG2964	Protein conserved in bacteria
HB761_09060	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HB761_09065	COG2923	Belongs to the DsrF TusC family
HB761_09070	COG2168	tRNA wobble position uridine thiolation
HB761_09085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HB761_09095	COG2906	2 iron, 2 sulfur cluster binding
HB761_09105	COG0281	malic enzyme
HB761_09115	COG0626	cystathionine gamma-synthase activity
HB761_09120	COG0460	homoserine dehydrogenase
HB761_09120	COG0527	aspartate kinase activity
HB761_09125	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HB761_09135	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HB761_09145	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HB761_09160	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HB761_09160	COG0165	Argininosuccinate lyase
HB761_09170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB761_09175	COG0678	peroxiredoxin activity
HB761_09175	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HB761_09185	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HB761_09230	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HB761_09240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HB761_09250	COG2965	DNA replication, synthesis of RNA primer
HB761_09270	COG0305	Participates in initiation and elongation during chromosome replication
HB761_09275	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HB761_09285	COG0432	Pfam Uncharacterised protein family UPF0047
HB761_09300	COG0735	belongs to the Fur family
HB761_09305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HB761_09325	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HB761_09390	COG0646	methionine synthase
HB761_09390	COG1410	methionine synthase
HB761_09395	COG0527	aspartate kinase activity
HB761_09400	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HB761_09410	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HB761_09425	COG0629	single-stranded DNA binding
HB761_09430	COG2199	diguanylate cyclase activity
HB761_09430	COG2200	EAL domain
HB761_09455	COG3267	Type II secretory pathway component ExeA
HB761_09455	COG3409	Peptidoglycan-binding domain 1 protein
HB761_09465	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB761_09470	COG1459	type II secretion system
HB761_09480	COG2165	general secretion pathway protein
HB761_09515	COG1077	Cell shape determining protein MreB Mrl
HB761_09520	COG1792	Involved in formation and maintenance of cell shape
HB761_09525	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HB761_09530	COG0424	maF-like protein
HB761_09540	COG3164	Protein of unknown function
HB761_09545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HB761_09550	COG0312	modulator of DNA gyrase
HB761_09555	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HB761_09570	COG0564	pseudouridine synthase activity
HB761_09575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HB761_09585	COG0312	modulator of DNA gyrase
HB761_09590	COG2239	Acts as a magnesium transporter
HB761_09595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB761_09605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB761_09610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HB761_09620	COG1137	ATPase activity
HB761_09625	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HB761_09635	COG0517	IMP dehydrogenase activity
HB761_09635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HB761_09645	COG1127	ABC transporter
HB761_09650	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HB761_09655	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HB761_09660	COG2854	intermembrane phospholipid transfer
HB761_09670	COG5007	Belongs to the BolA IbaG family
HB761_09680	COG0204	Acyl-transferase
HB761_09685	COG0251	oxidation-reduction process
HB761_09725	COG0456	acetyltransferase
HB761_09735	COG0525	valine-tRNA ligase activity
HB761_09740	COG2927	DNA polymerase III (CHI subunit)
HB761_09750	COG0795	lipopolysaccharide-transporting ATPase activity
HB761_09755	COG0795	lipopolysaccharide-transporting ATPase activity
HB761_09765	COG1028	Short-chain dehydrogenase reductase Sdr
HB761_09775	COG0726	polysaccharide deacetylase
HB761_09790	COG1447	Phosphotransferase system cellobiose-specific component IIA
HB761_09795	COG1486	melibiose metabolic process
HB761_09805	COG1609	Transcriptional regulator
HB761_09855	COG1012	belongs to the aldehyde dehydrogenase family
HB761_09955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HB761_09960	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HB761_09975	COG0762	integral membrane protein
HB761_09980	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HB761_09985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HB761_10000	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HB761_10005	COG1678	Uncharacterized ACR, COG1678
HB761_10010	COG0189	ligase activity
HB761_10015	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HB761_10020	COG2356	endonuclease I
HB761_10040	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HB761_10060	COG0191	fructose-bisphosphate aldolase activity
HB761_10065	COG0668	transmembrane transport
HB761_10080	COG0583	DNA-binding transcription factor activity
HB761_10085	COG2968	Membrane
HB761_10090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HB761_10100	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HB761_10110	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HB761_10120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB761_10125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB761_10145	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HB761_10155	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HB761_10160	COG1595	DNA-templated transcription, initiation
HB761_10175	COG3086	response to oxidative stress
HB761_10195	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HB761_10200	COG1381	Involved in DNA repair and RecF pathway recombination
HB761_10205	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HB761_10225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HB761_10230	COG3956	TIGRFAM MazG family protein
HB761_10240	COG0148	phosphopyruvate hydratase activity
HB761_10250	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HB761_10280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HB761_10290	COG1546	Belongs to the CinA family
HB761_10295	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HB761_10310	COG0527	aspartate kinase activity
HB761_10400	COG3630	sodium ion export across plasma membrane
HB761_10405	COG5016	pyruvate
HB761_10405	COG0511	ligase activity, forming carbon-carbon bonds
HB761_10410	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HB761_10420	COG1238	metal cluster binding
HB761_10425	COG0612	Peptidase, M16
HB761_10445	COG4536	flavin adenine dinucleotide binding
HB761_10450	COG4137	Cytochrome C assembly protein
HB761_10455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HB761_10460	COG0228	four-way junction DNA binding
HB761_10480	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HB761_10485	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HB761_10490	COG0237	dephospho-CoA kinase activity
HB761_10500	COG1459	type II secretion system
HB761_10505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB761_10510	COG4969	Belongs to the N-Me-Phe pilin family
HB761_10525	COG2186	Transcriptional regulator
HB761_10530	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HB761_10535	COG0508	dehydrogenase complex catalyzes the overall conversion of
HB761_10540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB761_10555	COG0288	reversible hydration of carbon dioxide
HB761_10560	COG0659	secondary active sulfate transmembrane transporter activity
HB761_10565	COG1131	(ABC) transporter
HB761_10570	COG0842	Transport permease protein
HB761_10575	COG1560	Kdo2-lipid A biosynthetic process
HB761_10590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HB761_10600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HB761_10615	COG1643	Atp-dependent helicase
HB761_10620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HB761_10625	COG1752	Esterase of the alpha-beta hydrolase superfamily
HB761_10630	COG1049	propionate catabolic process, 2-methylcitrate cycle
HB761_10645	COG0004	ammonium transporteR
HB761_10650	COG1840	ABC-type Fe3 transport system, periplasmic component
HB761_10660	COG3842	ATPase activity
HB761_10665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HB761_10680	COG2971	BadF BadG BcrA BcrD
HB761_10690	COG4608	Belongs to the ABC transporter superfamily
HB761_10695	COG0444	Belongs to the ABC transporter superfamily
HB761_10700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB761_10710	COG0747	negative chemotaxis
HB761_10715	COG2198	Histidine kinase
HB761_10715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB761_10715	COG2205	protein histidine kinase activity
HB761_10715	COG0784	Response regulator, receiver
HB761_10725	COG0628	permease
HB761_10745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB761_10750	COG0739	heme binding
HB761_10755	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HB761_10770	COG2027	D-alanyl-D-alanine carboxypeptidase
HB761_10775	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HB761_10780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB761_10785	COG1534	Rna-binding protein
HB761_10795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HB761_10800	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HB761_10815	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HB761_10835	COG0195	Participates in both transcription termination and antitermination
HB761_10855	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HB761_10875	COG0534	Mate efflux family protein
HB761_10880	COG0826	peptidase U32
HB761_10885	COG0826	peptidase U32
HB761_10895	COG3154	lipid carrier protein
HB761_10900	COG3153	acetyltransferase
HB761_10930	COG0084	hydrolase, TatD family'
HB761_10935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB761_10945	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HB761_10955	COG0813	purine-nucleoside phosphorylase activity
HB761_10965	COG0560	Phosphoserine phosphatase
HB761_10975	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HB761_10980	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HB761_11010	COG1022	Amp-dependent synthetase and ligase
HB761_11020	COG0583	DNA-binding transcription factor activity
HB761_11025	COG1609	Transcriptional regulator
HB761_11030	COG0768	penicillin binding
HB761_11035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HB761_11055	COG0741	lytic transglycosylase activity
HB761_11070	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HB761_11075	COG1349	DNA-binding transcription factor activity
HB761_11085	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HB761_11090	COG2271	Major facilitator Superfamily
HB761_11095	COG0584	glycerophosphoryl diester phosphodiesterase
HB761_11100	COG2171	N-acyltransferase activity
HB761_11115	COG3141	response to X-ray
HB761_11140	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HB761_11145	COG1074	ATP-dependent DNA helicase activity
HB761_11150	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HB761_11160	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HB761_11160	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HB761_11170	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HB761_11175	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HB761_11180	COG2166	iron-sulfur cluster assembly
HB761_11185	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HB761_11190	COG0693	protein deglycase activity
HB761_11195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HB761_11200	COG3248	Nucleoside-binding outer membrane protein
HB761_11215	COG1595	DNA-templated transcription, initiation
HB761_11245	COG0271	Belongs to the BolA IbaG family
HB761_11250	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HB761_11255	COG1805	sodium ion transport
HB761_11265	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HB761_11270	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HB761_11280	COG1477	protein flavinylation
HB761_11295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HB761_11300	COG0514	ATP-dependent DNA helicase (RecQ)
HB761_11305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB761_11320	COG0733	neurotransmitter:sodium symporter activity
HB761_11345	COG1720	tRNA m6t6A37 methyltransferase activity
HB761_11360	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HB761_11390	COG3098	single-species biofilm formation
HB761_11395	COG0564	pseudouridine synthase activity
HB761_11410	COG0024	Methionine aminopeptidase
HB761_11435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HB761_11440	COG0575	Belongs to the CDS family
HB761_11450	COG0750	zinc metalloprotease
HB761_11460	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HB761_11465	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HB761_11490	COG0587	DNA-directed DNA polymerase activity
HB761_11510	COG0347	Belongs to the P(II) protein family
HB761_11525	COG1388	LysM domain
HB761_11525	COG0741	lytic transglycosylase activity
HB761_11535	COG2226	methyltransferase
HB761_11545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HB761_11570	COG1960	acyl-CoA dehydrogenase activity
HB761_11575	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HB761_11580	COG0121	glutamine amidotransferase
HB761_11585	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HB761_11590	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HB761_11595	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HB761_11600	COG2233	PERMEase
HB761_11620	COG1393	Belongs to the ArsC family
HB761_11625	COG4783	chaperone-mediated protein folding
HB761_11640	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HB761_11645	COG2716	regulation of RNA biosynthetic process
HB761_11650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HB761_11655	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HB761_11675	COG1393	Belongs to the ArsC family
HB761_11700	COG2837	iron assimilation
HB761_11705	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB761_11710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB761_11715	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB761_11720	COG1334	flagellar protein FlaG
HB761_11725	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HB761_11735	COG1516	flagellar protein fliS
HB761_11755	COG1677	Flagellar hook-basal body complex protein FliE
HB761_11765	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HB761_11820	COG1987	bacterial-type flagellum assembly
HB761_11825	COG1684	flagellar biosynthetic protein fliR
HB761_11860	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HB761_11865	COG0643	Histidine kinase
HB761_11865	COG0784	Response regulator, receiver
HB761_11865	COG2198	Histidine kinase
HB761_11870	COG2201	protein-glutamate methylesterase activity
HB761_11875	COG1192	Involved in chromosome partitioning
HB761_11885	COG0835	chemotaxis
HB761_11895	COG4133	protoheme IX ABC transporter activity
HB761_11900	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HB761_11905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HB761_11920	COG1138	Cytochrome C-type biogenesis protein
HB761_11925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HB761_11935	COG4235	cytochrome complex assembly
HB761_11935	COG3088	subunit of a heme lyase
HB761_11940	COG2853	Lipoprotein
HB761_11945	COG2067	long-chain fatty acid transport protein
HB761_11950	COG2067	long-chain fatty acid transport protein
HB761_11965	COG0183	Belongs to the thiolase family
HB761_11980	COG2062	phosphohistidine phosphatase, SixA
HB761_11990	COG2890	protein-(glutamine-N5) methyltransferase activity
HB761_12000	COG2860	membrane
HB761_12005	COG3101	peptidyl-lysine hydroxylation
HB761_12025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HB761_12030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HB761_12035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HB761_12055	COG0285	dihydrofolate synthase activity
HB761_12060	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HB761_12065	COG1286	toxin biosynthetic process
HB761_12070	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HB761_12075	COG0583	DNA-binding transcription factor activity
HB761_12080	COG0745	RESPONSE REGULATOR receiver
HB761_12085	COG2832	Protein of unknown function (DUF454)
HB761_12095	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HB761_12105	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HB761_12110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HB761_12115	COG0814	amino acid
HB761_12120	COG0251	oxidation-reduction process
HB761_12130	COG2964	Protein conserved in bacteria
HB761_12140	COG2983	Belongs to the UPF0260 family
HB761_12145	COG2261	transglycosylase associated protein
HB761_12150	COG2985	domain, Protein
HB761_12155	COG0076	glutamate decarboxylase activity
HB761_12160	COG0668	transmembrane transport
HB761_12180	COG1785	Belongs to the alkaline phosphatase family
HB761_12200	COG2226	methyltransferase
HB761_12220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HB761_12225	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB761_12235	COG3139	Protein of unknown function (DUF1315)
HB761_12240	COG0252	asparaginase activity
HB761_12245	COG0616	signal peptide processing
HB761_12250	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB761_12250	COG1902	pentaerythritol trinitrate reductase activity
HB761_12255	COG0778	Nitroreductase
HB761_12260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HB761_12275	COG0123	including yeast histone deacetylase and acetoin utilization protein
HB761_12280	COG4269	membrane
HB761_12295	COG3083	sulfuric ester hydrolase activity
HB761_12320	COG1757	Na H antiporter
HB761_12325	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HB761_12330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB761_12335	COG2095	MarC family integral membrane protein
HB761_12340	COG1012	belongs to the aldehyde dehydrogenase family
HB761_12340	COG1454	alcohol dehydrogenase
HB761_12345	COG1028	Short-chain dehydrogenase reductase Sdr
HB761_12360	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HB761_12375	COG2056	Na+-H+ antiporter family
HB761_12385	COG2885	chlorophyll binding
HB761_12395	COG0346	lactoylglutathione lyase activity
HB761_12400	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HB761_12405	COG4660	Part of a membrane complex involved in electron transport
HB761_12410	COG4659	FMN binding
HB761_12415	COG4658	electron transport chain
HB761_12420	COG4656	Part of a membrane complex involved in electron transport
HB761_12430	COG4657	Part of a membrane complex involved in electron transport
HB761_12435	COG1882	Formate acetyltransferase
HB761_12490	COG0556	nucleotide-excision repair
HB761_12505	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HB761_12510	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HB761_12515	COG0521	Mo-molybdopterin cofactor biosynthetic process
HB761_12525	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HB761_12530	COG0314	molybdopterin synthase activity
HB761_12540	COG0601	transmembrane transport
HB761_12545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB761_12550	COG0444	Belongs to the ABC transporter superfamily
HB761_12560	COG0435	Glutathione S-transferase
HB761_12565	COG0280	phosphate acetyltransferase
HB761_12565	COG0857	belongs to the CobB CobQ family
HB761_12585	COG4120	Belongs to the binding-protein-dependent transport system permease family
HB761_12590	COG1122	ATPase activity
HB761_12605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HB761_12610	COG0653	protein targeting
HB761_12615	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HB761_12625	COG2186	Transcriptional regulator
HB761_12655	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HB761_12660	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HB761_12665	COG0659	secondary active sulfate transmembrane transporter activity
HB761_12670	COG1530	ribonuclease E activity
HB761_12675	COG0564	pseudouridine synthase activity
HB761_12680	COG0424	maF-like protein
HB761_12685	COG1399	metal-binding, possibly nucleic acid-binding protein
HB761_12700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HB761_12730	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HB761_12745	COG0084	hydrolase, TatD family'
HB761_12750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB761_12750	COG1263	PTS System
HB761_12765	COG0733	neurotransmitter:sodium symporter activity
HB761_12780	COG4667	esterase of the alpha-beta hydrolase superfamily
HB761_12805	COG2272	Belongs to the type-B carboxylesterase lipase family
HB761_12810	COG0457	Tetratricopeptide repeat
HB761_12810	COG3710	Transcriptional regulator
HB761_12825	COG1940	carbohydrate kinase activity
HB761_12830	COG0784	Response regulator, receiver
HB761_12830	COG0835	chemotaxis
HB761_12850	COG1028	Short-chain dehydrogenase reductase Sdr
HB761_12855	COG0616	signal peptide processing
HB761_12865	COG0539	negative regulation of cytoplasmic translation
HB761_12875	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HB761_12880	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HB761_12890	COG4166	transmembrane transport
HB761_12905	COG3009	Protein conserved in bacteria
HB761_12910	COG3008	intermembrane lipid transfer
HB761_12910	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HB761_12915	COG2995	paraquat-inducible protein a
HB761_12930	COG4232	protein-disulfide reductase activity
HB761_12935	COG3118	belongs to the thioredoxin family
HB761_12945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HB761_12955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB761_12970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB761_12980	COG0577	efflux transmembrane transporter activity
HB761_12990	COG1136	(ABC) transporter
HB761_12990	COG0577	efflux transmembrane transporter activity
HB761_13005	COG2176	DNA-directed DNA polymerase activity
HB761_13015	COG1217	gtp-binding protein TYPA
HB761_13025	COG3708	Transcriptional regulator
HB761_13025	COG2207	Transcriptional regulator
HB761_13035	COG3615	Tellurite resistance protein tehB
HB761_13085	COG5002	protein histidine kinase activity
HB761_13085	COG3850	Histidine kinase
HB761_13090	COG0745	RESPONSE REGULATOR receiver
HB761_13095	COG0463	Glycosyl transferase, family 2
HB761_13100	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HB761_13110	COG0840	transmembrane signaling receptor activity
HB761_13115	COG2175	clavaminate synthase activity
HB761_13150	COG1032	radical SAM domain protein
HB761_13155	COG5001	Diguanylate cyclase
HB761_13155	COG1716	ATPase activity
HB761_13185	COG2350	Protein conserved in bacteria
HB761_13215	COG1301	dicarboxylic acid transport
HB761_13220	COG0159	tryptophan synthase activity
HB761_13230	COG0134	indole-3-glycerol-phosphate synthase activity
HB761_13230	COG0135	phosphoribosylanthranilate isomerase activity
HB761_13240	COG0512	Glutamine amidotransferase of anthranilate synthase
HB761_13245	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HB761_13255	COG0613	PHP domain protein
HB761_13260	COG0009	L-threonylcarbamoyladenylate synthase
HB761_13270	COG1187	pseudouridine synthase activity
HB761_13290	COG0417	DNA replication proofreading
HB761_13295	COG2197	response regulator
HB761_13300	COG0322	excinuclease ABC activity
HB761_13340	COG0019	diaminopimelate decarboxylase activity
HB761_13355	COG1546	Belongs to the CinA family
HB761_13355	COG1058	Belongs to the CinA family
HB761_13365	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB761_13370	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB761_13410	COG3088	subunit of a heme lyase
HB761_13410	COG4235	cytochrome complex assembly
HB761_13445	COG2989	Protein conserved in bacteria
HB761_13450	COG3108	Peptidase M15
HB761_13455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HB761_13470	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HB761_13495	COG1846	Transcriptional regulator
HB761_13500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB761_13505	COG0840	transmembrane signaling receptor activity
HB761_13525	COG1448	Aminotransferase
HB761_13545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB761_13560	COG0017	Asparaginyl-tRNA synthetase
HB761_13570	COG0720	synthase
HB761_13575	COG2197	response regulator
HB761_13590	COG5001	Diguanylate cyclase
HB761_13590	COG3300	MHYT domain
HB761_13595	COG1760	l-serine dehydratase
HB761_13600	COG0814	amino acid
HB761_13615	COG0784	Response regulator, receiver
HB761_13615	COG2205	protein histidine kinase activity
HB761_13620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HB761_13635	COG3106	COG3106 Predicted ATPase
HB761_13650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB761_13695	COG0582	viral genome integration into host DNA
HB761_13710	COG5532	Uncharacterized conserved protein (DUF2303)
HB761_13750	COG4626	Terminase
HB761_13750	COG1802	Transcriptional regulator
HB761_13770	COG1403	HNH endonuclease
HB761_13805	COG1715	Restriction endonuclease
HB761_13825	COG3772	lysozyme
HB761_13855	COG1030	water channel activity
HB761_14125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB761_14145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB761_14230	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HB761_14230	COG0517	IMP dehydrogenase activity
HB761_14330	COG1280	lysine exporter protein (LysE YggA)
HB761_14470	COG3340	Belongs to the peptidase S51 family
HB761_14490	COG0456	acetyltransferase
HB761_14510	COG1280	lysine exporter protein (LysE YggA)
HB761_14515	COG1328	CTP reductase activity
HB761_14530	COG0861	Integral membrane protein TerC family
HB761_14540	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HB761_14545	COG4221	oxidoreductase activity
HB761_14555	COG0814	amino acid
HB761_14575	COG1132	(ABC) transporter
HB761_14580	COG1132	(ABC) transporter
HB761_14585	COG2165	general secretion pathway protein
HB761_14600	COG0443	Heat shock 70 kDa protein
HB761_14605	COG0443	Heat shock 70 kDa protein
HB761_14615	COG3706	GGDEF domain
HB761_14645	COG3227	Zinc metalloprotease (Elastase)
HB761_14705	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HB761_14745	COG1643	Atp-dependent helicase
HB761_14770	COG3063	Type IV pilus biogenesis stability protein PilW
HB761_14810	COG1280	lysine exporter protein (LysE YggA)
HB761_14885	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HB761_14895	COG1280	lysine exporter protein (LysE YggA)
HB761_14905	COG1280	lysine exporter protein (LysE YggA)
HB761_14935	COG1115	amino acid carrier protein
HB761_14960	COG1368	sulfuric ester hydrolase activity
HB761_14975	COG0215	cysteine-tRNA ligase activity
HB761_14985	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HB761_14995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB761_15010	COG1858	cytochrome C peroxidase
HB761_15015	COG1404	Belongs to the peptidase S8 family
HB761_15060	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HB761_15065	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HB761_15075	COG1280	lysine exporter protein (LysE YggA)
HB761_15150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB761_15170	COG3290	protein histidine kinase activity
HB761_15175	COG4565	transcriptional regulatory protein
HB761_15180	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HB761_15185	COG0363	glucosamine-6-phosphate deaminase activity
HB761_15190	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HB761_15200	COG3284	Transcriptional regulator
HB761_15205	COG1012	belongs to the aldehyde dehydrogenase family
HB761_15210	COG2358	TRAP transporter, solute receptor (TAXI family
HB761_15220	COG0730	response to heat
HB761_15260	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HB761_15270	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HB761_15275	COG0372	Belongs to the citrate synthase family
HB761_15285	COG2828	Protein conserved in bacteria
HB761_15320	COG0561	phosphatase activity
HB761_15325	COG0602	queuosine metabolic process
HB761_15335	COG3706	GGDEF domain
HB761_15395	COG1254	Belongs to the acylphosphatase family
HB761_15400	COG2920	part of a sulfur-relay system
HB761_15405	COG0670	Belongs to the BI1 family
HB761_15410	COG1126	abc transporter atp-binding protein
HB761_15415	COG0765	amino acid transport
HB761_15420	COG4597	amino acid ABC transporter
HB761_15425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB761_15440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB761_15465	COG3008	intermembrane lipid transfer
HB761_15470	COG2995	paraquat-inducible protein a
HB761_15475	COG1132	(ABC) transporter
HB761_15480	COG1956	GAF domain-containing protein
HB761_15485	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HB761_15500	COG0308	aminopeptidase N
HB761_15510	COG2902	Dehydrogenase
HB761_15535	COG0488	(ABC) transporter
HB761_15555	COG1067	ATP-dependent peptidase activity
HB761_15655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB761_15665	COG0561	phosphatase activity
HB761_15670	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HB761_15675	COG3623	hexulose-6-phosphate isomerase
HB761_15710	COG2259	Doxx family
HB761_15720	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HB761_15725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HB761_15795	COG1609	Transcriptional regulator
HB761_15810	COG0395	ABC-type sugar transport system, permease component
HB761_15815	COG2723	6-phospho-beta-galactosidase activity
HB761_15820	COG3842	ATPase activity
HB761_15825	COG1609	Transcriptional regulator
HB761_15835	COG0564	pseudouridine synthase activity
HB761_15840	COG0561	phosphatase activity
HB761_15860	COG3152	Membrane
HB761_15875	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HB761_15890	COG0583	DNA-binding transcription factor activity
HB761_15940	COG2076	Multidrug Resistance protein
HB761_15950	COG1357	PFAM Pentapeptide repeats (8 copies)
HB761_15955	COG3047	cAMP biosynthetic process
HB761_16045	COG0668	transmembrane transport
HB761_16090	COG3835	regulator
HB761_16095	COG1929	Belongs to the glycerate kinase type-1 family
HB761_16100	COG0477	Major facilitator Superfamily
HB761_16120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB761_16170	COG1028	Short-chain dehydrogenase reductase Sdr
HB761_16190	COG0671	phosphoesterase, PA-phosphatase related
HB761_16200	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HB761_16205	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HB761_16210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB761_16215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB761_16220	COG1116	anion transmembrane transporter activity
HB761_16225	COG0351	phosphomethylpyrimidine kinase
HB761_16230	COG0312	modulator of DNA gyrase
HB761_16235	COG0312	modulator of DNA gyrase
HB761_16295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HB761_16305	COG0584	glycerophosphoryl diester phosphodiesterase
HB761_16310	COG0745	RESPONSE REGULATOR receiver
HB761_16315	COG2205	protein histidine kinase activity
HB761_16330	COG0811	peptide transport
HB761_16335	COG0811	peptide transport
HB761_16340	COG0848	biopolymer transport protein
HB761_16385	COG0803	Belongs to the bacterial solute-binding protein 9 family
HB761_16390	COG1121	(ABC) transporter
HB761_16395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB761_16410	COG1770	oligopeptidase
HB761_16415	COG2814	Major facilitator Superfamily
HB761_16420	COG0010	Belongs to the arginase family
HB761_16425	COG1166	arginine decarboxylase activity
HB761_16435	COG0189	ligase activity
HB761_16435	COG4067	protein conserved in archaea
HB761_16440	COG0189	ligase activity
HB761_16460	COG0583	DNA-binding transcription factor activity
HB761_16485	COG2723	6-phospho-beta-galactosidase activity
HB761_16500	COG1114	Component of the transport system for branched-chain amino acids
HB761_16515	COG0579	oxidoreductase
HB761_16520	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HB761_16535	COG3033	Beta-eliminating lyase
HB761_16550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB761_16555	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HB761_16590	COG3706	GGDEF domain
HB761_16595	COG0415	Belongs to the DNA photolyase family
HB761_16600	COG3046	protein related to deoxyribodipyrimidine photolyase
HB761_16615	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB761_16615	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB761_16620	COG1765	OsmC-like protein
HB761_16665	COG1011	Hydrolase
HB761_16690	COG3240	lipase activity
HB761_16710	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HB761_16720	COG1840	ABC-type Fe3 transport system, periplasmic component
HB761_16725	COG3842	ATPase activity
HB761_16750	COG2990	Protein conserved in bacteria
HB761_16760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB761_16765	COG2866	Carboxypeptidase
HB761_16775	COG0583	DNA-binding transcription factor activity
HB761_16800	COG3104	oligopeptide transport
HB761_16805	COG1760	l-serine dehydratase
HB761_16830	COG0741	lytic transglycosylase activity
HB761_16830	COG1388	LysM domain
HB761_16850	COG1815	bacterial-type flagellum-dependent cell motility
HB761_16855	COG1558	bacterial-type flagellum-dependent cell motility
HB761_16860	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HB761_16865	COG1749	Flagellar hook protein flgE
HB761_16870	COG4787	bacterial-type flagellum-dependent cell motility
HB761_16875	COG4786	Flagellar basal body rod
HB761_16880	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HB761_16885	COG1706	bacterial-type flagellum-dependent cell motility
HB761_16895	COG1256	bacterial-type flagellum assembly
HB761_16895	COG4786	Flagellar basal body rod
HB761_16900	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB761_16965	COG0384	phenazine biosynthesis protein PhzF
HB761_16975	COG1360	Flagellar Motor Protein
HB761_16980	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HB761_16985	COG1191	sigma factor activity
HB761_16990	COG1580	Controls the rotational direction of flagella during chemotaxis
HB761_17005	COG1516	flagellar protein fliS
HB761_17010	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HB761_17020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB761_17035	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HB761_17045	COG1987	bacterial-type flagellum assembly
HB761_17145	COG0346	lactoylglutathione lyase activity
HB761_17160	COG0156	8-amino-7-oxononanoate synthase activity
HB761_17165	COG1063	alcohol dehydrogenase
HB761_17170	COG4974	Belongs to the 'phage' integrase family
HB761_17290	COG4695	Portal protein
HB761_17445	COG1063	alcohol dehydrogenase
HB761_17470	COG2203	Gaf domain
HB761_17470	COG2199	diguanylate cyclase activity
HB761_17475	COG2223	nitrite transmembrane transporter activity
HB761_17480	COG1063	alcohol dehydrogenase
HB761_17490	COG0668	transmembrane transport
HB761_17500	COG1304	FMN binding
HB761_17505	COG1620	l-lactate permease
HB761_17510	COG0583	DNA-binding transcription factor activity
HB761_17515	COG1505	serine-type exopeptidase activity
HB761_17520	COG4172	Belongs to the ABC transporter superfamily
HB761_17530	COG1067	ATP-dependent peptidase activity
HB761_17540	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HB761_17560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB761_17580	COG1122	ATPase activity
HB761_17590	COG1566	PFAM secretion protein HlyD family protein
HB761_17620	COG0813	purine-nucleoside phosphorylase activity
HB761_17625	COG3272	Protein of unknown function (DUF1722)
HB761_17630	COG0789	Transcriptional regulator
HB761_17635	COG0415	Belongs to the DNA photolyase family
HB761_17640	COG1388	LysM domain
HB761_17640	COG1376	ErfK ybiS ycfS ynhG family protein
HB761_17650	COG0513	Belongs to the DEAD box helicase family
HB761_17660	COG1770	oligopeptidase
HB761_17685	COG0840	transmembrane signaling receptor activity
HB761_17695	COG0573	inorganic phosphate transmembrane transporter activity
HB761_17700	COG0581	inorganic phosphate transmembrane transporter activity
HB761_17705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HB761_17720	COG2304	oxidoreductase activity
HB761_17740	COG0714	Associated with various cellular activities
HB761_17750	COG0840	transmembrane signaling receptor activity
HB761_17760	COG2197	response regulator
HB761_17785	COG2204	response regulator
HB761_17790	COG3852	Histidine kinase
HB761_17795	COG1028	Short-chain dehydrogenase reductase Sdr
HB761_17825	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
HB761_17845	COG1252	NADH dehydrogenase
HB761_17850	COG1301	dicarboxylic acid transport
HB761_17855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB761_17880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB761_17880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB761_17880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB761_17885	COG2207	Transcriptional regulator
HB761_17895	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB761_17900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB761_17910	COG2084	Dehydrogenase
HB761_17915	COG0753	catalase activity
HB761_17925	COG2130	NADP-dependent
HB761_17930	COG1309	transcriptional regulator
HB761_17975	COG3206	protein involved in exopolysaccharide biosynthesis
HB761_17975	COG0489	protein tyrosine kinase activity
HB761_17990	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HB761_17995	COG3842	ATPase activity
HB761_18005	COG1175	transmembrane transport
HB761_18010	COG3833	ABC-type maltose transport systems, permease component
HB761_18040	COG2354	Protein conserved in bacteria
HB761_18050	COG0401	homolog of Blt101
HB761_18055	COG3217	Mosc domain protein beta barrel domain protein
HB761_18055	COG0633	Ferredoxin
HB761_18055	COG3217	Mosc domain protein beta barrel domain protein
HB761_18055	COG0633	Ferredoxin
HB761_18065	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HB761_18105	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HB761_18110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB761_18120	COG0848	biopolymer transport protein
HB761_18125	COG0811	peptide transport
HB761_18130	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HB761_18140	COG3721	Heme iron utilization protein
HB761_18145	COG0748	coenzyme F420 binding
HB761_18155	COG0835	chemotaxis
HB761_18155	COG0784	Response regulator, receiver
HB761_18160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB761_18165	COG0366	Alpha amylase catalytic
HB761_18200	COG0583	DNA-binding transcription factor activity
HB761_18215	COG2249	NAD(P)H dehydrogenase (quinone) activity
HB761_18230	COG4977	sequence-specific DNA binding
HB761_18235	COG0673	inositol 2-dehydrogenase activity
HB761_18240	COG2194	sulfuric ester hydrolase activity
HB761_18245	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HB761_18255	COG2205	protein histidine kinase activity
HB761_18260	COG0745	RESPONSE REGULATOR receiver
HB761_18265	COG4221	oxidoreductase activity
HB761_18280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB761_18300	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HB761_18310	COG2814	Major facilitator Superfamily
HB761_18325	COG1418	mRNA catabolic process
HB761_18340	COG0402	S-adenosylhomocysteine deaminase activity
HB761_18345	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HB761_18350	COG2239	Acts as a magnesium transporter
HB761_18355	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HB761_18360	COG1566	PFAM secretion protein HlyD family protein
HB761_18385	COG0745	RESPONSE REGULATOR receiver
HB761_18390	COG2205	protein histidine kinase activity
HB761_18400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB761_18405	COG0531	amino acid
HB761_18410	COG1522	sequence-specific DNA binding
HB761_18420	COG0583	DNA-binding transcription factor activity
HB761_18445	COG0673	inositol 2-dehydrogenase activity
HB761_18525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB761_18530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB761_18540	COG1280	lysine exporter protein (LysE YggA)
HB761_18550	COG0183	Belongs to the thiolase family
HB761_18570	COG3005	denitrification pathway
HB761_18590	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB761_18595	COG3850	Histidine kinase
HB761_18600	COG2197	response regulator
HB761_18615	COG2195	Cleaves the N-terminal amino acid of tripeptides
HB761_18625	COG0840	transmembrane signaling receptor activity
HB761_18635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB761_18640	COG0545	Peptidyl-prolyl cis-trans isomerase
HB761_18670	COG1278	Cold shock
HB761_18675	COG3036	rescue of stalled ribosome
HB761_18685	COG2199	diguanylate cyclase activity
HB761_18700	COG1136	(ABC) transporter
HB761_18700	COG0577	efflux transmembrane transporter activity
HB761_18705	COG0577	efflux transmembrane transporter activity
HB761_18705	COG1136	(ABC) transporter
HB761_18715	COG0840	transmembrane signaling receptor activity
HB761_18720	COG0783	Belongs to the Dps family
HB761_18730	COG1619	proteins homologs of microcin C7 resistance protein MccF
HB761_18735	COG2133	pyrroloquinoline quinone binding
HB761_18740	COG1454	alcohol dehydrogenase
HB761_18745	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HB761_18770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB761_18780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HB761_18785	COG3186	Phenylalanine-4-hydroxylase
HB761_18810	COG3530	Putative quorum-sensing-regulated virulence factor
HB761_18835	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HB761_18840	COG1845	cytochrome c oxidase, subunit III
HB761_18845	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HB761_18850	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HB761_18860	COG0454	-acetyltransferase
HB761_18890	COG0523	cobalamin synthesis protein
HB761_18895	COG5001	Diguanylate cyclase
HB761_18895	COG3447	MASE1 domain protein
HB761_18895	COG5002	protein histidine kinase activity
HB761_18900	COG0513	Belongs to the DEAD box helicase family
HB761_18920	COG2200	EAL domain
HB761_18940	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HB761_18955	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
HB761_18960	COG0513	Belongs to the DEAD box helicase family
HB761_18970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HB761_18985	COG3278	Belongs to the heme-copper respiratory oxidase family
HB761_19030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HB761_19035	COG1960	acyl-CoA dehydrogenase activity
HB761_19045	COG0183	Belongs to the thiolase family
HB761_19060	COG1024	Enoyl-CoA hydratase
HB761_19065	COG1024	Enoyl-CoA hydratase
HB761_19075	COG1028	Short-chain dehydrogenase reductase Sdr
HB761_19080	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HB761_19085	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HB761_19090	COG1845	cytochrome c oxidase, subunit III
HB761_19095	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HB761_19105	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB761_19105	COG1902	pentaerythritol trinitrate reductase activity
HB761_19110	COG0583	DNA-binding transcription factor activity
HB761_19120	COG1012	belongs to the aldehyde dehydrogenase family
HB761_19130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB761_19165	COG1126	abc transporter atp-binding protein
HB761_19170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB761_19175	COG4215	(ABC) transporter
HB761_19180	COG4160	amino acid transport
HB761_19215	COG5002	protein histidine kinase activity
HB761_19220	COG2200	EAL domain
HB761_19265	COG0443	Heat shock 70 kDa protein
HB761_19295	COG1785	Belongs to the alkaline phosphatase family
HB761_19320	COG0814	amino acid
HB761_19375	COG0739	heme binding
HB761_19485	COG2814	Major facilitator Superfamily
HB761_19500	COG2816	NAD+ diphosphatase activity
HB761_19525	COG2153	protein acetylation
HB761_19530	COG1132	(ABC) transporter
HB761_19550	COG0583	DNA-binding transcription factor activity
HB761_19580	COG1120	ATPase activity
HB761_19585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB761_19590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB761_19595	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HB761_19635	COG0803	Belongs to the bacterial solute-binding protein 9 family
HB761_19645	COG3005	denitrification pathway
HB761_19770	COG2801	Transposase and inactivated derivatives
HB761_19810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB761_19820	COG1028	Short-chain dehydrogenase reductase Sdr
HB761_19835	COG0583	DNA-binding transcription factor activity
HB761_19850	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HB761_19860	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HB761_19870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB761_19875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB761_19890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB761_19890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB761_19890	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HB761_19895	COG1105	Belongs to the carbohydrate kinase PfkB family
HB761_19900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB761_19900	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB761_19905	COG1609	Transcriptional regulator
HB761_19920	COG2199	diguanylate cyclase activity
HB761_19920	COG2200	EAL domain
HB761_19920	COG2203	Gaf domain
HB761_19925	COG0765	amino acid transport
HB761_19930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB761_19935	COG0765	amino acid transport
HB761_19940	COG1126	abc transporter atp-binding protein
HB761_19950	COG1979	alcohol dehydrogenase
HB761_19955	COG2207	Transcriptional regulator
HB761_19965	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HB761_19975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB761_19995	COG0546	phosphoglycolate phosphatase activity
HB761_20010	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HB761_20015	COG0513	Belongs to the DEAD box helicase family
HB761_20020	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HB761_20035	COG3038	cytochrome b561
HB761_20045	COG2116	formate transmembrane transporter activity
HB761_20050	COG0583	DNA-binding transcription factor activity
HB761_20060	COG3593	DNA synthesis involved in DNA repair
HB761_20065	COG0737	Belongs to the 5'-nucleotidase family
HB761_20080	COG1410	methionine synthase
HB761_20080	COG0646	methionine synthase
HB761_20085	COG0076	glutamate decarboxylase activity
HB761_20130	COG2267	carboxylic ester hydrolase activity
HB761_20135	COG2067	long-chain fatty acid transport protein
HB761_20145	COG0501	Belongs to the peptidase M48B family
HB761_20150	COG2050	protein possibly involved in aromatic compounds catabolism
HB761_20195	COG5001	Diguanylate cyclase
HB761_20195	COG3300	MHYT domain
HB761_20200	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HB761_20210	COG4181	ATPase activity
HB761_20215	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HB761_20225	COG1984	allophanate hydrolase subunit 2
HB761_20230	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HB761_20240	COG3447	MASE1 domain protein
HB761_20240	COG5002	protein histidine kinase activity
HB761_20240	COG5001	Diguanylate cyclase
HB761_20245	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HB761_20250	COG4771	TonB-dependent receptor
HB761_20250	COG1629	transport
HB761_20255	COG0583	DNA-binding transcription factor activity
HB761_20260	COG0045	succinate-CoA ligase (ADP-forming) activity
HB761_20260	COG1042	CoA-binding domain protein
HB761_20260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB761_20280	COG0023	Translation Initiation Factor
HB761_20295	COG3140	Belongs to the UPF0181 family
HB761_20320	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HB761_20325	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HB761_20345	COG2203	Gaf domain
HB761_20345	COG3706	GGDEF domain
HB761_20345	COG4251	negative regulation of phosphorylation
HB761_20345	COG5001	Diguanylate cyclase
HB761_20355	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HB761_20360	COG4149	molybdate abc transporter
HB761_20365	COG0725	ABC transporter, periplasmic molybdate-binding protein
HB761_20375	COG3111	PFAM Bacterial OB fold (BOF) protein
HB761_20410	COG0602	queuosine metabolic process
HB761_20415	COG1328	CTP reductase activity
HB761_20470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HB761_20475	COG3118	belongs to the thioredoxin family
HB761_20505	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HB761_20520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HB761_20520	COG1648	precorrin-2 dehydrogenase activity
HB761_20580	COG0277	FAD linked oxidase domain protein
HB761_20585	COG0583	DNA-binding transcription factor activity
HB761_20600	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HB761_20615	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HB761_20625	COG1288	antiporter activity
HB761_20635	COG3040	lipid binding
HB761_20665	COG3469	chitinase activity
HB761_20675	COG0419	ATPase involved in DNA repair
HB761_20680	COG0420	3'-5' exonuclease activity
HB761_20705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HB761_20710	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HB761_20725	COG0840	transmembrane signaling receptor activity
HB761_20750	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HB761_20750	COG2755	lipolytic protein G-D-S-L family
HB761_20760	COG5642	Protein of unknown function (DUF2384)
HB761_20800	COG0671	phosphoesterase, PA-phosphatase related
HB761_20810	COG2962	Rard protein
HB761_20820	COG0835	chemotaxis
HB761_20820	COG0784	Response regulator, receiver
HB761_20825	COG0778	Nitroreductase
HB761_20830	COG2197	response regulator
HB761_20845	COG4771	TonB-dependent receptor
HB761_20900	COG1522	sequence-specific DNA binding
HB761_20935	COG0515	serine threonine protein kinase
HB761_20960	COG3501	Rhs element vgr protein
HB761_20975	COG2204	response regulator
HB761_21000	COG0739	heme binding
HB761_21015	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HB761_21045	COG3069	C4-dicarboxylate transmembrane transporter activity
HB761_21075	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HB761_21085	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HB761_21145	COG0784	Response regulator, receiver
HB761_21145	COG2198	Histidine kinase
HB761_21145	COG2205	protein histidine kinase activity
HB761_21150	COG1879	ABC-type sugar transport system periplasmic component
HB761_21160	COG0210	DNA helicase
HB761_21165	COG1289	transmembrane transporter activity
HB761_21190	COG0789	Transcriptional regulator
HB761_21195	COG4604	ABC transporter, ATP-binding protein
HB761_21200	COG4605	iron ion homeostasis
HB761_21205	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB761_21210	COG4607	ABC-type enterochelin transport system periplasmic component
HB761_21225	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HB761_21240	COG1609	Transcriptional regulator
HB761_21245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB761_21250	COG1879	ABC-type sugar transport system periplasmic component
HB761_21255	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB761_21260	COG1129	ABC transporter
HB761_21270	COG5001	Diguanylate cyclase
HB761_21295	COG0586	Pfam SNARE associated Golgi protein
HB761_21335	COG0784	Response regulator, receiver
HB761_21335	COG2205	protein histidine kinase activity
HB761_21360	COG0330	HflC and HflK could
HB761_21370	COG4175	Glycine betaine
HB761_21370	COG0517	IMP dehydrogenase activity
HB761_21375	COG4176	ABC-type proline glycine betaine transport system permease component
HB761_21410	COG2885	chlorophyll binding
HB761_21450	COG0455	bacterial-type flagellum organization
HB761_21460	COG4964	Belongs to the GSP D family
HB761_21480	COG0583	DNA-binding transcription factor activity
HB761_21530	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HB761_21530	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HB761_21545	COG4989	oxidoreductase activity
HB761_21575	COG0303	'Molybdopterin
HB761_21580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HB761_21615	COG2897	thiosulfate sulfurtransferase activity
HB761_21635	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HB761_21640	COG0840	transmembrane signaling receptor activity
HB761_21650	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB761_21665	COG1612	heme a metabolic process
HB761_21690	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HB761_21705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HB761_21715	COG1280	lysine exporter protein (LysE YggA)
HB761_21735	COG0179	Fumarylacetoacetate (FAA) hydrolase
HB761_21750	COG0697	spore germination
HB761_21765	COG2814	Major facilitator Superfamily
HB761_21770	COG0583	DNA-binding transcription factor activity
HB761_21800	COG1120	ATPase activity
HB761_21805	COG5001	Diguanylate cyclase
HB761_21810	COG0739	heme binding
HB761_21830	COG3314	Sporulation integral membrane protein YlbJ
HB761_21840	COG0814	amino acid
HB761_21875	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HB761_21880	COG1120	ATPase activity
HB761_21905	COG0798	PFAM Bile acid sodium symporter
HB761_21925	COG0251	oxidation-reduction process
HB761_21930	COG2706	6-phosphogluconolactonase activity
HB761_21940	COG0800	Aldolase
HB761_21945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB761_21950	COG4145	pantothenate transmembrane transporter activity
HB761_21960	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HB761_21980	COG1131	(ABC) transporter
HB761_21985	COG0842	Transport permease protein
HB761_22025	COG1280	lysine exporter protein (LysE YggA)
HB761_22030	COG0583	DNA-binding transcription factor activity
HB761_22040	COG0494	nUDIX hydrolase
HB761_22055	COG1858	cytochrome C peroxidase
HB761_22085	COG1505	serine-type exopeptidase activity
HB761_22090	COG0488	(ABC) transporter
HB761_22100	COG0589	response to stress
HB761_22110	COG0584	glycerophosphoryl diester phosphodiesterase
HB761_22120	COG1175	transmembrane transport
HB761_22125	COG0395	ABC-type sugar transport system, permease component
HB761_22130	COG3842	ATPase activity
HB761_22155	COG0523	cobalamin synthesis protein
HB761_22165	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HB761_22175	COG4667	esterase of the alpha-beta hydrolase superfamily
HB761_22180	COG1741	Belongs to the pirin family
HB761_22185	COG1278	Cold shock
HB761_22200	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HB761_22210	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB761_22220	COG1686	Belongs to the peptidase S11 family
HB761_22225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB761_22230	COG0625	glutathione transferase activity
HB761_22285	COG1764	response to oxidative stress
HB761_22290	COG2084	Dehydrogenase
HB761_22295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB761_22300	COG0823	Involved in the tonB-independent uptake of proteins
HB761_22315	COG1028	Short-chain dehydrogenase reductase Sdr
HB761_22320	COG3483	tryptophan 2,3-dioxygenase activity
HB761_22430	COG0625	glutathione transferase activity
HB761_22465	COG0519	Catalyzes the synthesis of GMP from XMP
HB761_22545	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HB761_22575	COG0307	riboflavin synthase, alpha
HB761_22620	COG1683	Conserved Protein
HB761_22680	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HB761_22680	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HB761_22700	COG1028	Short-chain dehydrogenase reductase Sdr
HB761_22725	COG3746	phosphate-selective porin O and P
HB761_22745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB761_22785	COG0513	Belongs to the DEAD box helicase family
HB761_22790	COG0583	DNA-binding transcription factor activity
HB761_22810	COG1902	pentaerythritol trinitrate reductase activity
HB761_22815	COG3853	Toxic anion resistance protein (TelA)
HB761_22825	COG2255	four-way junction helicase activity
HB761_22840	COG3122	Protein conserved in bacteria
HB761_22845	COG2321	neutral zinc metallopeptidase
HB761_22855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HB761_22860	COG1215	transferase activity, transferring glycosyl groups
HB761_22870	COG0583	DNA-binding transcription factor activity
HB761_22875	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HB761_22885	COG2207	Transcriptional regulator
HB761_22890	COG2807	transmembrane transport
HB761_22900	COG0574	Belongs to the PEP-utilizing enzyme family
HB761_22900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HB761_22925	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HB761_22935	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HB761_22970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB761_22980	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HB761_23020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB761_23070	COG4948	Mandelate Racemase Muconate Lactonizing
HB761_23110	COG4176	ABC-type proline glycine betaine transport system permease component
HB761_23115	COG3448	diguanylate cyclase activity
HB761_23115	COG4175	Glycine betaine
HB761_23130	COG0583	DNA-binding transcription factor activity
HB761_23140	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HB761_23150	COG3136	membrane protein required for alginate biosynthesis
HB761_23170	COG1335	isochorismatase
HB761_23185	COG1349	DNA-binding transcription factor activity
HB761_23190	COG0346	lactoylglutathione lyase activity
HB761_23195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB761_23195	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB761_23205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB761_23225	COG1280	lysine exporter protein (LysE YggA)
HB761_23230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HB761_23245	COG0488	(ABC) transporter
HB761_23250	COG0435	Glutathione S-transferase
HB761_23255	COG0431	NADPH-dependent FMN reductase
HB761_23265	COG4628	conserved protein (DUF2132)
HB761_23270	COG0488	(ABC) transporter
HB761_23285	COG0346	lactoylglutathione lyase activity
HB761_23290	COG0384	phenazine biosynthesis protein PhzF
HB761_23310	COG2205	protein histidine kinase activity
HB761_23315	COG0745	RESPONSE REGULATOR receiver
HB761_23325	COG0454	-acetyltransferase
HB761_23335	COG2814	Major facilitator Superfamily
HB761_23345	COG2988	succinylglutamate desuccinylase activity
HB761_23355	COG0628	permease
HB761_23360	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HB761_23375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB761_23385	COG4628	conserved protein (DUF2132)
HB761_23390	COG0583	DNA-binding transcription factor activity
HB761_23400	COG1686	Belongs to the peptidase S11 family
HB761_23420	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB761_23425	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB761_23440	COG0415	Belongs to the DNA photolyase family
HB761_23445	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HB761_23455	COG4667	esterase of the alpha-beta hydrolase superfamily
HB761_23460	COG2095	MarC family integral membrane protein
HB761_23470	COG1596	polysaccharide export
HB761_23480	COG3206	protein involved in exopolysaccharide biosynthesis
HB761_23480	COG0489	protein tyrosine kinase activity
HB761_23500	COG1301	dicarboxylic acid transport
HB761_23505	COG3339	Conserved Protein
HB761_23520	COG2207	Transcriptional regulator
HB761_23535	COG0366	Alpha amylase catalytic
HB761_23540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HB761_23545	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HB761_23550	COG1640	4-alpha-glucanotransferase
HB761_23555	COG0058	SHG alpha-glucan phosphorylase activity
HB761_23575	COG1999	signal sequence binding
HB761_23590	COG1162	GTPase activity
HB761_23595	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HB761_23630	COG2356	endonuclease I
HB761_23670	COG2814	Major facilitator Superfamily
HB761_23680	COG0739	heme binding
HB761_23715	COG3121	Chaperone
HB761_23720	COG3188	usher protein
HB761_23750	COG0612	Peptidase, M16
HB761_23755	COG0840	transmembrane signaling receptor activity
HB761_23775	COG1335	isochorismatase
HB761_23780	COG1136	(ABC) transporter
HB761_23785	COG0577	efflux transmembrane transporter activity
HB761_23820	COG1764	response to oxidative stress
HB761_23825	COG1846	Transcriptional regulator
HB761_23840	COG3634	alkyl hydroperoxide reductase activity
HB761_23850	COG2610	gluconate transmembrane transporter activity
HB761_23855	COG3622	Belongs to the hyi family
HB761_23860	COG0235	Class ii aldolase
HB761_23865	COG3395	kinase activity
HB761_23870	COG2084	Dehydrogenase
HB761_23875	COG1349	DNA-binding transcription factor activity
HB761_23905	COG1522	sequence-specific DNA binding
HB761_23910	COG0544	peptidyl-prolyl cis-trans isomerase activity
HB761_23915	COG0544	peptidyl-prolyl cis-trans isomerase activity
HB761_23920	COG0544	peptidyl-prolyl cis-trans isomerase activity
HB761_23935	COG2258	MOSC domain
HB761_23940	COG2153	protein acetylation
HB761_23950	COG3713	MltA-interacting MipA family protein
HB761_23955	COG0513	Belongs to the DEAD box helicase family
HB761_23975	COG1132	(ABC) transporter
HB761_24155	COG0655	NAD(P)H dehydrogenase (quinone) activity
HB761_24160	COG4166	transmembrane transport
HB761_24190	COG1595	DNA-templated transcription, initiation
HB761_24230	COG0848	biopolymer transport protein
HB761_24235	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HB761_24240	COG1444	tRNA N-acetyltransferase activity
HB761_24265	COG4608	Belongs to the ABC transporter superfamily
HB761_24270	COG0444	Belongs to the ABC transporter superfamily
HB761_24280	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
HB761_24280	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HB761_24335	COG3275	phosphorelay sensor kinase activity
HB761_24340	COG3279	Response regulator of the LytR AlgR family
HB761_24350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HB761_24370	COG0786	glutamate:sodium symporter activity
HB761_24375	COG1028	Short-chain dehydrogenase reductase Sdr
HB761_24440	COG2897	thiosulfate sulfurtransferase activity
HB761_24450	COG1131	(ABC) transporter
HB761_24455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB761_24480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB761_24490	COG0561	phosphatase activity
HB761_24495	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HB761_24530	COG0840	transmembrane signaling receptor activity
HB761_24640	COG1192	Involved in chromosome partitioning
HB761_24645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HB761_24650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HB761_24800	COG0778	Nitroreductase
HB761_24875	COG0840	transmembrane signaling receptor activity