locus-tag	class	description
BWP24_00020	COG2132	Multicopper oxidase
BWP24_00040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BWP24_00045	COG2104	thiamine diphosphate biosynthetic process
BWP24_00060	COG0006	proline dipeptidase activity
BWP24_00060	COG0006	proline dipeptidase activity
BWP24_00070	COG2814	Major facilitator Superfamily
BWP24_00090	COG3220	belongs to the UPF0276 family
BWP24_00100	COG0210	DNA helicase
BWP24_00110	COG0405	Gamma-glutamyltransferase
BWP24_00115	COG1280	lysine exporter protein (LysE YggA)
BWP24_00135	COG2962	Rard protein
BWP24_00140	COG0514	ATP-dependent DNA helicase (RecQ)
BWP24_00150	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BWP24_00165	COG3118	belongs to the thioredoxin family
BWP24_00170	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BWP24_00180	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BWP24_00185	COG0633	Ferredoxin
BWP24_00225	COG3071	HemY protein
BWP24_00230	COG2959	enzyme of heme biosynthesis
BWP24_00235	COG1587	Uroporphyrinogen-III synthase
BWP24_00245	COG3072	Adenylate cyclase
BWP24_00260	COG0019	diaminopimelate decarboxylase activity
BWP24_00280	COG1011	Hydrolase
BWP24_00285	COG2199	diguanylate cyclase activity
BWP24_00285	COG2200	EAL domain
BWP24_00285	COG3287	FIST C domain
BWP24_00305	COG0561	phosphatase activity
BWP24_00310	COG2267	carboxylic ester hydrolase activity
BWP24_00315	COG1280	lysine exporter protein (LysE YggA)
BWP24_00320	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BWP24_00325	COG0640	Transcriptional regulator
BWP24_00330	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BWP24_00380	COG2095	MarC family integral membrane protein
BWP24_00390	COG0742	ribosomal rna small subunit methyltransferase
BWP24_00395	COG0552	protein localization to endoplasmic reticulum
BWP24_00395	COG0552	protein localization to endoplasmic reticulum
BWP24_00400	COG2884	Cell division ATP-binding protein ftsE
BWP24_00405	COG2177	Part of the ABC transporter FtsEX involved in
BWP24_00425	COG0705	Rhomboid family
BWP24_00430	COG1580	Controls the rotational direction of flagella during chemotaxis
BWP24_00435	COG3161	chorismate lyase activity
BWP24_00445	COG2937	Belongs to the GPAT DAPAT family
BWP24_00465	COG0534	Mate efflux family protein
BWP24_00545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BWP24_00555	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BWP24_00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BWP24_00605	COG0250	Participates in transcription elongation, termination and antitermination
BWP24_00620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BWP24_00640	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BWP24_00645	COG2816	NAD+ diphosphatase activity
BWP24_00665	COG1573	uracil-dna glycosylase
BWP24_00675	COG3068	Protein conserved in bacteria
BWP24_00680	COG1253	flavin adenine dinucleotide binding
BWP24_00695	COG0151	Belongs to the GarS family
BWP24_00705	COG0789	Transcriptional regulator
BWP24_00710	COG3710	Transcriptional regulator
BWP24_00725	COG0531	amino acid
BWP24_00730	COG1982	Orn Lys Arg decarboxylase major
BWP24_00860	COG3706	GGDEF domain
BWP24_00865	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BWP24_00870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BWP24_00880	COG0439	Biotin carboxylase
BWP24_00885	COG0511	ligase activity, forming carbon-carbon bonds
BWP24_00890	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BWP24_00895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BWP24_00910	COG2814	Major facilitator Superfamily
BWP24_00915	COG2198	Histidine kinase
BWP24_00915	COG2205	protein histidine kinase activity
BWP24_00915	COG0784	Response regulator, receiver
BWP24_00935	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BWP24_00945	COG2095	MarC family integral membrane protein
BWP24_00955	COG4232	protein-disulfide reductase activity
BWP24_00960	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BWP24_00965	COG1027	Aspartate ammonia-lyase
BWP24_00970	COG3030	protein affecting phage T7 exclusion by the F plasmid
BWP24_00975	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BWP24_00985	COG2205	protein histidine kinase activity
BWP24_00990	COG0745	RESPONSE REGULATOR receiver
BWP24_01010	COG0534	Mate efflux family protein
BWP24_01015	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BWP24_01035	COG1509	lysine 2,3-aminomutase activity
BWP24_01065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BWP24_01070	COG1053	succinate dehydrogenase
BWP24_01095	COG4942	peptidase
BWP24_01100	COG1045	serine acetyltransferase
BWP24_01115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWP24_01120	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BWP24_01135	COG0471	metal ion transport
BWP24_01145	COG1162	GTPase activity
BWP24_01220	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BWP24_01225	COG0802	atpase or kinase
BWP24_01230	COG0860	N-Acetylmuramoyl-L-alanine amidase
BWP24_01235	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BWP24_01250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BWP24_01255	COG0330	HflC and HflK could
BWP24_01260	COG0330	HflC and HflK could
BWP24_01265	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BWP24_01270	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BWP24_01275	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BWP24_01280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BWP24_01280	COG1017	nitric oxide dioxygenase activity
BWP24_01290	COG0557	exoribonuclease II activity
BWP24_01295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BWP24_01300	COG0546	phosphoglycolate phosphatase activity
BWP24_01320	COG0512	Glutamine amidotransferase of anthranilate synthase
BWP24_01325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BWP24_01345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BWP24_01350	COG3954	Phosphoribulokinase
BWP24_01360	COG0429	hydrolase of the alpha beta-hydrolase fold
BWP24_01370	COG0488	(ABC) transporter
BWP24_01375	COG2249	NAD(P)H dehydrogenase (quinone) activity
BWP24_01390	COG1047	Peptidyl-prolyl cis-trans
BWP24_01395	COG1446	asparaginase
BWP24_01410	COG0545	Peptidyl-prolyl cis-trans isomerase
BWP24_01415	COG2964	Protein conserved in bacteria
BWP24_01420	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BWP24_01425	COG2923	Belongs to the DsrF TusC family
BWP24_01430	COG2168	tRNA wobble position uridine thiolation
BWP24_01445	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BWP24_01455	COG2906	2 iron, 2 sulfur cluster binding
BWP24_01465	COG0281	malic enzyme
BWP24_01475	COG0626	cystathionine gamma-synthase activity
BWP24_01480	COG0527	aspartate kinase activity
BWP24_01480	COG0460	homoserine dehydrogenase
BWP24_01485	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BWP24_01495	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BWP24_01505	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BWP24_01520	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BWP24_01520	COG0165	Argininosuccinate lyase
BWP24_01530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWP24_01535	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BWP24_01535	COG0678	peroxiredoxin activity
BWP24_01545	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BWP24_01590	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BWP24_01595	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BWP24_01605	COG2965	DNA replication, synthesis of RNA primer
BWP24_01625	COG0305	Participates in initiation and elongation during chromosome replication
BWP24_01630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BWP24_01640	COG0432	Pfam Uncharacterised protein family UPF0047
BWP24_01655	COG0735	belongs to the Fur family
BWP24_01660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BWP24_01680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BWP24_01750	COG1410	methionine synthase
BWP24_01750	COG0646	methionine synthase
BWP24_01755	COG0527	aspartate kinase activity
BWP24_01765	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BWP24_01775	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BWP24_01790	COG0629	single-stranded DNA binding
BWP24_01795	COG2200	EAL domain
BWP24_01795	COG2199	diguanylate cyclase activity
BWP24_01820	COG3409	Peptidoglycan-binding domain 1 protein
BWP24_01820	COG3267	Type II secretory pathway component ExeA
BWP24_01830	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BWP24_01835	COG1459	type II secretion system
BWP24_01880	COG1077	Cell shape determining protein MreB Mrl
BWP24_01885	COG1792	Involved in formation and maintenance of cell shape
BWP24_01890	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BWP24_01895	COG0424	maF-like protein
BWP24_01900	COG1530	ribonuclease E activity
BWP24_01905	COG3164	Protein of unknown function
BWP24_01910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BWP24_01915	COG0312	modulator of DNA gyrase
BWP24_01920	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BWP24_01935	COG0564	pseudouridine synthase activity
BWP24_01940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BWP24_01950	COG0312	modulator of DNA gyrase
BWP24_01955	COG2239	Acts as a magnesium transporter
BWP24_01960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWP24_01970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWP24_01975	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BWP24_01985	COG1137	ATPase activity
BWP24_01990	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BWP24_02000	COG0517	IMP dehydrogenase activity
BWP24_02000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BWP24_02010	COG1127	ABC transporter
BWP24_02015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BWP24_02020	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BWP24_02025	COG2854	intermembrane phospholipid transfer
BWP24_02035	COG5007	Belongs to the BolA IbaG family
BWP24_02045	COG0204	Acyl-transferase
BWP24_02050	COG0251	oxidation-reduction process
BWP24_02090	COG0456	acetyltransferase
BWP24_02100	COG0525	valine-tRNA ligase activity
BWP24_02105	COG2927	DNA polymerase III (CHI subunit)
BWP24_02115	COG0795	lipopolysaccharide-transporting ATPase activity
BWP24_02120	COG0795	lipopolysaccharide-transporting ATPase activity
BWP24_02130	COG1028	Short-chain dehydrogenase reductase Sdr
BWP24_02140	COG0726	polysaccharide deacetylase
BWP24_02145	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BWP24_02155	COG1447	Phosphotransferase system cellobiose-specific component IIA
BWP24_02160	COG1486	melibiose metabolic process
BWP24_02225	COG1012	belongs to the aldehyde dehydrogenase family
BWP24_02325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BWP24_02330	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BWP24_02345	COG0762	integral membrane protein
BWP24_02350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BWP24_02355	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BWP24_02370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BWP24_02375	COG1678	Uncharacterized ACR, COG1678
BWP24_02380	COG0189	ligase activity
BWP24_02385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BWP24_02390	COG2356	endonuclease I
BWP24_02410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BWP24_02430	COG0191	fructose-bisphosphate aldolase activity
BWP24_02435	COG0668	transmembrane transport
BWP24_02450	COG0583	DNA-binding transcription factor activity
BWP24_02455	COG2968	Membrane
BWP24_02460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BWP24_02470	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BWP24_02480	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BWP24_02490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWP24_02495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWP24_02515	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BWP24_02525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BWP24_02530	COG1595	DNA-templated transcription, initiation
BWP24_02545	COG3086	response to oxidative stress
BWP24_02555	COG0681	Belongs to the peptidase S26 family
BWP24_02565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BWP24_02570	COG1381	Involved in DNA repair and RecF pathway recombination
BWP24_02575	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BWP24_02600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BWP24_02605	COG3956	TIGRFAM MazG family protein
BWP24_02615	COG0148	phosphopyruvate hydratase activity
BWP24_02625	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BWP24_02655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BWP24_02665	COG1546	Belongs to the CinA family
BWP24_02670	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BWP24_02685	COG0527	aspartate kinase activity
BWP24_02750	COG0511	ligase activity, forming carbon-carbon bonds
BWP24_02750	COG5016	pyruvate
BWP24_02755	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BWP24_02765	COG1238	metal cluster binding
BWP24_02770	COG0612	Peptidase, M16
BWP24_02790	COG4536	flavin adenine dinucleotide binding
BWP24_02795	COG4137	Cytochrome C assembly protein
BWP24_02800	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BWP24_02825	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BWP24_02830	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BWP24_02835	COG0237	dephospho-CoA kinase activity
BWP24_02845	COG1459	type II secretion system
BWP24_02850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BWP24_02875	COG2186	Transcriptional regulator
BWP24_02880	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BWP24_02885	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWP24_02890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWP24_02910	COG0288	reversible hydration of carbon dioxide
BWP24_02915	COG0659	secondary active sulfate transmembrane transporter activity
BWP24_02920	COG1131	(ABC) transporter
BWP24_02925	COG0842	Transport permease protein
BWP24_02930	COG1560	Kdo2-lipid A biosynthetic process
BWP24_02945	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BWP24_02955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BWP24_02960	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BWP24_02970	COG1643	Atp-dependent helicase
BWP24_02975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BWP24_02980	COG1752	Esterase of the alpha-beta hydrolase superfamily
BWP24_02985	COG1049	propionate catabolic process, 2-methylcitrate cycle
BWP24_03000	COG0004	ammonium transporteR
BWP24_03005	COG1840	ABC-type Fe3 transport system, periplasmic component
BWP24_03015	COG3842	ATPase activity
BWP24_03020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BWP24_03035	COG2971	BadF BadG BcrA BcrD
BWP24_03045	COG4608	Belongs to the ABC transporter superfamily
BWP24_03050	COG0444	Belongs to the ABC transporter superfamily
BWP24_03055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWP24_03065	COG0747	negative chemotaxis
BWP24_03070	COG2205	protein histidine kinase activity
BWP24_03070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWP24_03070	COG2198	Histidine kinase
BWP24_03070	COG0784	Response regulator, receiver
BWP24_03085	COG0628	permease
BWP24_03105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWP24_03110	COG0739	heme binding
BWP24_03115	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BWP24_03130	COG2027	D-alanyl-D-alanine carboxypeptidase
BWP24_03135	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BWP24_03140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BWP24_03145	COG1534	Rna-binding protein
BWP24_03155	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BWP24_03160	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BWP24_03175	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BWP24_03195	COG0195	Participates in both transcription termination and antitermination
BWP24_03215	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BWP24_03235	COG0534	Mate efflux family protein
BWP24_03260	COG3153	acetyltransferase
BWP24_03280	COG3706	GGDEF domain
BWP24_03290	COG0084	hydrolase, TatD family'
BWP24_03295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BWP24_03305	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BWP24_03315	COG0813	purine-nucleoside phosphorylase activity
BWP24_03325	COG0560	Phosphoserine phosphatase
BWP24_03335	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BWP24_03340	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BWP24_03345	COG0583	DNA-binding transcription factor activity
BWP24_03380	COG1022	Amp-dependent synthetase and ligase
BWP24_03385	COG2169	Transcriptional regulator
BWP24_03405	COG4964	Belongs to the GSP D family
BWP24_03465	COG0583	DNA-binding transcription factor activity
BWP24_03470	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BWP24_03470	COG3408	Glycogen debranching enzyme
BWP24_03480	COG0531	amino acid
BWP24_03485	COG2731	YhcH YjgK YiaL family protein
BWP24_03490	COG3250	beta-galactosidase activity
BWP24_03495	COG1609	Transcriptional regulator
BWP24_03500	COG0768	penicillin binding
BWP24_03505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BWP24_03510	COG1085	galactose-1-phosphate uridylyltransferase
BWP24_03520	COG2017	converts alpha-aldose to the beta-anomer
BWP24_03530	COG1609	Transcriptional regulator
BWP24_03535	COG1263	PTS System
BWP24_03535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWP24_03545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BWP24_03570	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BWP24_03575	COG1349	DNA-binding transcription factor activity
BWP24_03585	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BWP24_03590	COG2271	Major facilitator Superfamily
BWP24_03595	COG0584	glycerophosphoryl diester phosphodiesterase
BWP24_03610	COG2171	N-acyltransferase activity
BWP24_03625	COG3141	response to X-ray
BWP24_03645	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BWP24_03650	COG1074	ATP-dependent DNA helicase activity
BWP24_03655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BWP24_03675	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BWP24_03675	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BWP24_03690	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BWP24_03695	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BWP24_03700	COG2166	iron-sulfur cluster assembly
BWP24_03705	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BWP24_03710	COG0693	protein deglycase activity
BWP24_03715	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BWP24_03735	COG1595	DNA-templated transcription, initiation
BWP24_03765	COG0271	Belongs to the BolA IbaG family
BWP24_03800	COG1477	protein flavinylation
BWP24_03810	COG0745	RESPONSE REGULATOR receiver
BWP24_03810	COG3706	GGDEF domain
BWP24_03815	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BWP24_03820	COG0514	ATP-dependent DNA helicase (RecQ)
BWP24_03825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BWP24_03840	COG0733	neurotransmitter:sodium symporter activity
BWP24_03865	COG1720	tRNA m6t6A37 methyltransferase activity
BWP24_03880	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BWP24_03915	COG3098	single-species biofilm formation
BWP24_03920	COG0564	pseudouridine synthase activity
BWP24_03935	COG0024	Methionine aminopeptidase
BWP24_03960	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BWP24_03965	COG0575	Belongs to the CDS family
BWP24_03975	COG0750	zinc metalloprotease
BWP24_03985	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BWP24_03990	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BWP24_04015	COG0587	DNA-directed DNA polymerase activity
BWP24_04035	COG0347	Belongs to the P(II) protein family
BWP24_04050	COG0741	lytic transglycosylase activity
BWP24_04050	COG1388	LysM domain
BWP24_04060	COG2226	methyltransferase
BWP24_04070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BWP24_04095	COG1960	acyl-CoA dehydrogenase activity
BWP24_04100	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BWP24_04105	COG0121	glutamine amidotransferase
BWP24_04110	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BWP24_04115	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BWP24_04120	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BWP24_04125	COG2233	PERMEase
BWP24_04145	COG1393	Belongs to the ArsC family
BWP24_04150	COG4783	chaperone-mediated protein folding
BWP24_04165	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BWP24_04170	COG2716	regulation of RNA biosynthetic process
BWP24_04175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BWP24_04200	COG1393	Belongs to the ArsC family
BWP24_04230	COG2837	iron assimilation
BWP24_04235	COG2169	Transcriptional regulator
BWP24_04240	COG1486	melibiose metabolic process
BWP24_04245	COG2211	Major facilitator Superfamily
BWP24_04255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWP24_04265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWP24_04270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWP24_04275	COG1334	flagellar protein FlaG
BWP24_04280	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BWP24_04290	COG1516	flagellar protein fliS
BWP24_04300	COG4191	Histidine kinase
BWP24_04305	COG2204	response regulator
BWP24_04310	COG1677	Flagellar hook-basal body complex protein FliE
BWP24_04320	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BWP24_04375	COG1987	bacterial-type flagellum assembly
BWP24_04380	COG1684	flagellar biosynthetic protein fliR
BWP24_04400	COG0455	bacterial-type flagellum organization
BWP24_04415	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BWP24_04420	COG2198	Histidine kinase
BWP24_04420	COG0643	Histidine kinase
BWP24_04425	COG2201	protein-glutamate methylesterase activity
BWP24_04430	COG1192	Involved in chromosome partitioning
BWP24_04440	COG0835	chemotaxis
BWP24_04450	COG4133	protoheme IX ABC transporter activity
BWP24_04455	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BWP24_04460	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BWP24_04475	COG1138	Cytochrome C-type biogenesis protein
BWP24_04480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWP24_04490	COG4235	cytochrome complex assembly
BWP24_04490	COG3088	subunit of a heme lyase
BWP24_04495	COG2853	Lipoprotein
BWP24_04505	COG2067	long-chain fatty acid transport protein
BWP24_04525	COG0183	Belongs to the thiolase family
BWP24_04545	COG2062	phosphohistidine phosphatase, SixA
BWP24_04555	COG2890	protein-(glutamine-N5) methyltransferase activity
BWP24_04565	COG2860	membrane
BWP24_04570	COG3101	peptidyl-lysine hydroxylation
BWP24_04595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BWP24_04605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BWP24_04610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BWP24_04635	COG0285	dihydrofolate synthase activity
BWP24_04640	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BWP24_04645	COG1286	toxin biosynthetic process
BWP24_04650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BWP24_04655	COG0583	DNA-binding transcription factor activity
BWP24_04660	COG0745	RESPONSE REGULATOR receiver
BWP24_04665	COG2832	Protein of unknown function (DUF454)
BWP24_04675	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BWP24_04685	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BWP24_04690	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BWP24_04695	COG0814	amino acid
BWP24_04700	COG0251	oxidation-reduction process
BWP24_04710	COG2964	Protein conserved in bacteria
BWP24_04720	COG2983	Belongs to the UPF0260 family
BWP24_04725	COG2261	transglycosylase associated protein
BWP24_04730	COG2985	domain, Protein
BWP24_04735	COG0076	glutamate decarboxylase activity
BWP24_04740	COG0668	transmembrane transport
BWP24_04750	COG0346	lactoylglutathione lyase activity
BWP24_04760	COG1785	Belongs to the alkaline phosphatase family
BWP24_04780	COG2226	methyltransferase
BWP24_04800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BWP24_04805	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWP24_04815	COG3139	Protein of unknown function (DUF1315)
BWP24_04820	COG0252	asparaginase activity
BWP24_04825	COG0616	signal peptide processing
BWP24_04830	COG0446	pyridine nucleotide-disulphide oxidoreductase
BWP24_04830	COG1902	pentaerythritol trinitrate reductase activity
BWP24_04835	COG0778	Nitroreductase
BWP24_04840	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BWP24_04855	COG0123	including yeast histone deacetylase and acetoin utilization protein
BWP24_04865	COG4269	membrane
BWP24_04880	COG3083	sulfuric ester hydrolase activity
BWP24_04905	COG1757	Na H antiporter
BWP24_04910	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BWP24_04920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BWP24_04925	COG2095	MarC family integral membrane protein
BWP24_04930	COG1454	alcohol dehydrogenase
BWP24_04930	COG1012	belongs to the aldehyde dehydrogenase family
BWP24_04935	COG1028	Short-chain dehydrogenase reductase Sdr
BWP24_04950	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BWP24_04955	COG4974	Belongs to the 'phage' integrase family
BWP24_04975	COG1403	HNH endonuclease
BWP24_05135	COG3504	Conjugal transfer protein
BWP24_05140	COG3736	Type IV secretory pathway, component VirB8
BWP24_05160	COG3451	type IV secretory pathway VirB4
BWP24_05195	COG2056	Na+-H+ antiporter family
BWP24_05205	COG2885	chlorophyll binding
BWP24_05215	COG0346	lactoylglutathione lyase activity
BWP24_05220	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BWP24_05225	COG4660	Part of a membrane complex involved in electron transport
BWP24_05230	COG4659	FMN binding
BWP24_05235	COG4658	electron transport chain
BWP24_05240	COG4656	Part of a membrane complex involved in electron transport
BWP24_05250	COG4657	Part of a membrane complex involved in electron transport
BWP24_05255	COG1882	Formate acetyltransferase
BWP24_05260	COG0745	RESPONSE REGULATOR receiver
BWP24_05295	COG0556	nucleotide-excision repair
BWP24_05310	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BWP24_05315	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BWP24_05320	COG0521	Mo-molybdopterin cofactor biosynthetic process
BWP24_05330	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BWP24_05335	COG0314	molybdopterin synthase activity
BWP24_05345	COG0601	transmembrane transport
BWP24_05350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWP24_05355	COG0444	Belongs to the ABC transporter superfamily
BWP24_05365	COG0435	Glutathione S-transferase
BWP24_05370	COG3174	membrane
BWP24_05375	COG0280	phosphate acetyltransferase
BWP24_05375	COG0857	belongs to the CobB CobQ family
BWP24_05400	COG4120	Belongs to the binding-protein-dependent transport system permease family
BWP24_05405	COG1122	ATPase activity
BWP24_05410	COG0366	Alpha amylase catalytic
BWP24_05415	COG3706	GGDEF domain
BWP24_05415	COG0745	RESPONSE REGULATOR receiver
BWP24_05420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BWP24_05425	COG0653	protein targeting
BWP24_05430	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BWP24_05440	COG2186	Transcriptional regulator
BWP24_05470	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BWP24_05475	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BWP24_05480	COG0659	secondary active sulfate transmembrane transporter activity
BWP24_05490	COG1530	ribonuclease E activity
BWP24_05495	COG0564	pseudouridine synthase activity
BWP24_05500	COG0424	maF-like protein
BWP24_05505	COG1399	metal-binding, possibly nucleic acid-binding protein
BWP24_05520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BWP24_05550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BWP24_05565	COG0084	hydrolase, TatD family'
BWP24_05570	COG1263	PTS System
BWP24_05570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWP24_05580	COG0733	neurotransmitter:sodium symporter activity
BWP24_05590	COG4667	esterase of the alpha-beta hydrolase superfamily
BWP24_05615	COG2272	Belongs to the type-B carboxylesterase lipase family
BWP24_05625	COG3710	Transcriptional regulator
BWP24_05640	COG1940	carbohydrate kinase activity
BWP24_05645	COG0835	chemotaxis
BWP24_05645	COG0784	Response regulator, receiver
BWP24_05665	COG1028	Short-chain dehydrogenase reductase Sdr
BWP24_05670	COG0616	signal peptide processing
BWP24_05680	COG0539	negative regulation of cytoplasmic translation
BWP24_05690	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BWP24_05695	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BWP24_05705	COG4166	transmembrane transport
BWP24_05725	COG3009	Protein conserved in bacteria
BWP24_05730	COG3008	intermembrane lipid transfer
BWP24_05730	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BWP24_05735	COG2995	paraquat-inducible protein a
BWP24_05750	COG4232	protein-disulfide reductase activity
BWP24_05755	COG3118	belongs to the thioredoxin family
BWP24_05765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BWP24_05795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BWP24_05805	COG0577	efflux transmembrane transporter activity
BWP24_05810	COG1136	(ABC) transporter
BWP24_05810	COG0577	efflux transmembrane transporter activity
BWP24_05815	COG1136	(ABC) transporter
BWP24_05815	COG0577	efflux transmembrane transporter activity
BWP24_05830	COG2176	DNA-directed DNA polymerase activity
BWP24_05845	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BWP24_05890	COG0515	serine threonine protein kinase
BWP24_05895	COG5002	protein histidine kinase activity
BWP24_05895	COG3850	Histidine kinase
BWP24_05900	COG0745	RESPONSE REGULATOR receiver
BWP24_05905	COG0463	Glycosyl transferase, family 2
BWP24_05910	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BWP24_05920	COG0840	transmembrane signaling receptor activity
BWP24_05925	COG2175	clavaminate synthase activity
BWP24_05930	COG2964	Protein conserved in bacteria
BWP24_05945	COG0446	pyridine nucleotide-disulphide oxidoreductase
BWP24_05965	COG1032	radical SAM domain protein
BWP24_05970	COG1716	ATPase activity
BWP24_05970	COG5001	Diguanylate cyclase
BWP24_05985	COG0583	DNA-binding transcription factor activity
BWP24_06000	COG2350	Protein conserved in bacteria
BWP24_06005	COG1607	acyl-coa hydrolase
BWP24_06030	COG1301	dicarboxylic acid transport
BWP24_06035	COG0159	tryptophan synthase activity
BWP24_06045	COG0134	indole-3-glycerol-phosphate synthase activity
BWP24_06045	COG0135	phosphoribosylanthranilate isomerase activity
BWP24_06055	COG0512	Glutamine amidotransferase of anthranilate synthase
BWP24_06060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BWP24_06070	COG0613	PHP domain protein
BWP24_06075	COG0009	L-threonylcarbamoyladenylate synthase
BWP24_06085	COG1187	pseudouridine synthase activity
BWP24_06105	COG0417	DNA replication proofreading
BWP24_06110	COG2197	response regulator
BWP24_06115	COG0322	excinuclease ABC activity
BWP24_06160	COG0019	diaminopimelate decarboxylase activity
BWP24_06175	COG1546	Belongs to the CinA family
BWP24_06175	COG1058	Belongs to the CinA family
BWP24_06185	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BWP24_06190	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BWP24_06215	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BWP24_06225	COG0437	4 iron, 4 sulfur cluster binding
BWP24_06230	COG3301	Polysulphide reductase, NrfD
BWP24_06235	COG1138	Cytochrome C-type biogenesis protein
BWP24_06245	COG4235	cytochrome complex assembly
BWP24_06245	COG3088	subunit of a heme lyase
BWP24_06280	COG2989	Protein conserved in bacteria
BWP24_06285	COG3108	Peptidase M15
BWP24_06290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWP24_06305	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BWP24_06330	COG1846	Transcriptional regulator
BWP24_06335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BWP24_06340	COG0840	transmembrane signaling receptor activity
BWP24_06360	COG1448	Aminotransferase
BWP24_06365	COG3437	response regulator, receiver
BWP24_06365	COG2770	Histidine kinase
BWP24_06380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWP24_06395	COG0017	Asparaginyl-tRNA synthetase
BWP24_06405	COG0720	synthase
BWP24_06410	COG2197	response regulator
BWP24_06425	COG1760	l-serine dehydratase
BWP24_06430	COG0814	amino acid
BWP24_06450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BWP24_06465	COG3106	COG3106 Predicted ATPase
BWP24_06480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWP24_06620	COG0519	Catalyzes the synthesis of GMP from XMP
BWP24_07280	COG0494	nUDIX hydrolase
BWP24_07285	COG1714	RDD family
BWP24_07310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BWP24_07490	COG4221	oxidoreductase activity
BWP24_07505	COG3340	Belongs to the peptidase S51 family
BWP24_07535	COG0456	acetyltransferase
BWP24_07540	COG0471	metal ion transport
BWP24_07545	COG4191	Histidine kinase
BWP24_07545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWP24_07570	COG1328	CTP reductase activity
BWP24_07575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BWP24_07585	COG0861	Integral membrane protein TerC family
BWP24_07595	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BWP24_07600	COG4221	oxidoreductase activity
BWP24_07605	COG1454	alcohol dehydrogenase
BWP24_07610	COG0814	amino acid
BWP24_07630	COG1132	(ABC) transporter
BWP24_07635	COG1132	(ABC) transporter
BWP24_07645	COG0583	DNA-binding transcription factor activity
BWP24_07670	COG0443	Heat shock 70 kDa protein
BWP24_07675	COG0443	Heat shock 70 kDa protein
BWP24_07685	COG3706	GGDEF domain
BWP24_07715	COG3227	Zinc metalloprotease (Elastase)
BWP24_07735	COG3842	ATPase activity
BWP24_07740	COG3459	Glycosyltransferase 36 associated
BWP24_07750	COG1653	transport
BWP24_07760	COG0395	ABC-type sugar transport system, permease component
BWP24_07775	COG0243	molybdopterin cofactor binding
BWP24_07780	COG0437	4 iron, 4 sulfur cluster binding
BWP24_07785	COG3302	dmso reductase anchor subunit
BWP24_07800	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BWP24_07805	COG1643	Atp-dependent helicase
BWP24_07830	COG3063	Type IV pilus biogenesis stability protein PilW
BWP24_07860	COG0531	amino acid
BWP24_07865	COG1280	lysine exporter protein (LysE YggA)
BWP24_07870	COG1560	Kdo2-lipid A biosynthetic process
BWP24_07890	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BWP24_07895	COG1280	lysine exporter protein (LysE YggA)
BWP24_07930	COG1115	amino acid carrier protein
BWP24_07950	COG1368	sulfuric ester hydrolase activity
BWP24_07965	COG0215	cysteine-tRNA ligase activity
BWP24_07970	COG0534	Mate efflux family protein
BWP24_07975	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BWP24_07985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BWP24_07990	COG0456	acetyltransferase
BWP24_07995	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BWP24_08000	COG0662	Cupin 2, conserved barrel domain protein
BWP24_08005	COG0527	aspartate kinase activity
BWP24_08015	COG1858	cytochrome C peroxidase
BWP24_08020	COG1404	Belongs to the peptidase S8 family
BWP24_08025	COG3227	Zinc metalloprotease (Elastase)
BWP24_08040	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BWP24_08045	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BWP24_08050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BWP24_08075	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BWP24_08080	COG0667	Aldo Keto reductase
BWP24_08095	COG0583	DNA-binding transcription factor activity
BWP24_08100	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BWP24_08105	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BWP24_08110	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BWP24_08115	COG0679	Auxin Efflux Carrier
BWP24_08155	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BWP24_08190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BWP24_08205	COG3290	protein histidine kinase activity
BWP24_08210	COG4565	transcriptional regulatory protein
BWP24_08215	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BWP24_08220	COG0363	glucosamine-6-phosphate deaminase activity
BWP24_08225	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BWP24_08255	COG3284	Transcriptional regulator
BWP24_08260	COG1012	belongs to the aldehyde dehydrogenase family
BWP24_08270	COG0730	response to heat
BWP24_08300	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BWP24_08305	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BWP24_08400	COG3501	Rhs element vgr protein
BWP24_08415	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BWP24_08420	COG0372	Belongs to the citrate synthase family
BWP24_08430	COG2828	Protein conserved in bacteria
BWP24_08445	COG3119	arylsulfatase activity
BWP24_08465	COG0561	phosphatase activity
BWP24_08470	COG0602	queuosine metabolic process
BWP24_08480	COG3706	GGDEF domain
BWP24_08530	COG0840	transmembrane signaling receptor activity
BWP24_08535	COG1254	Belongs to the acylphosphatase family
BWP24_08540	COG2920	part of a sulfur-relay system
BWP24_08550	COG0670	Belongs to the BI1 family
BWP24_08555	COG1126	abc transporter atp-binding protein
BWP24_08560	COG0765	amino acid transport
BWP24_08565	COG4597	amino acid ABC transporter
BWP24_08570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWP24_08585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BWP24_08610	COG3008	intermembrane lipid transfer
BWP24_08615	COG2995	paraquat-inducible protein a
BWP24_08620	COG1132	(ABC) transporter
BWP24_08625	COG1956	GAF domain-containing protein
BWP24_08630	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BWP24_08645	COG0308	aminopeptidase N
BWP24_08655	COG2902	Dehydrogenase
BWP24_08705	COG1067	ATP-dependent peptidase activity
BWP24_08735	COG2801	Transposase and inactivated derivatives
BWP24_08740	COG0784	Response regulator, receiver
BWP24_08740	COG2205	protein histidine kinase activity
BWP24_08755	COG3278	Belongs to the heme-copper respiratory oxidase family
BWP24_08770	COG2010	Cytochrome c
BWP24_08780	COG2217	Heavy metal translocating P-type atpase
BWP24_08795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BWP24_08800	COG0589	response to stress
BWP24_08825	COG3842	ATPase activity
BWP24_08830	COG1176	ABC-type spermidine putrescine transport system, permease component I
BWP24_08835	COG1177	transmembrane transport
BWP24_08840	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BWP24_08845	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BWP24_08850	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BWP24_08870	COG0437	4 iron, 4 sulfur cluster binding
BWP24_08875	COG3383	formate dehydrogenase (NAD+) activity
BWP24_08875	COG0243	molybdopterin cofactor binding
BWP24_08885	COG3381	protein complex oligomerization
BWP24_08905	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BWP24_08920	COG0488	(ABC) transporter
BWP24_08935	COG4191	Histidine kinase
BWP24_08940	COG2204	response regulator
BWP24_08950	COG4662	Binding-protein-dependent transport system inner membrane component
BWP24_08955	COG3842	ATPase activity
BWP24_08965	COG0303	'Molybdopterin
BWP24_08975	COG1940	carbohydrate kinase activity
BWP24_09035	COG0791	NLP P60 protein
BWP24_09045	COG3706	GGDEF domain
BWP24_09050	COG2201	protein-glutamate methylesterase activity
BWP24_09065	COG0307	riboflavin synthase, alpha
BWP24_09070	COG0534	Mate efflux family protein
BWP24_09080	COG1793	dna ligase
BWP24_09090	COG2885	chlorophyll binding
BWP24_09110	COG2204	response regulator
BWP24_09115	COG0438	transferase activity, transferring glycosyl groups
BWP24_09120	COG0438	transferase activity, transferring glycosyl groups
BWP24_09150	COG0438	transferase activity, transferring glycosyl groups
BWP24_09155	COG1215	transferase activity, transferring glycosyl groups
BWP24_09160	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BWP24_09170	COG3064	Membrane
BWP24_09195	COG3300	MHYT domain
BWP24_09195	COG5001	Diguanylate cyclase
BWP24_09200	COG3850	Histidine kinase
BWP24_09200	COG2205	protein histidine kinase activity
BWP24_09200	COG4999	Histidine kinase
BWP24_09200	COG3437	response regulator, receiver
BWP24_09220	COG0110	maltose O-acetyltransferase activity
BWP24_09245	COG1846	Transcriptional regulator
BWP24_09255	COG1482	cell wall glycoprotein biosynthetic process
BWP24_09270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWP24_09290	COG0383	alpha-mannosidase activity
BWP24_09300	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BWP24_09325	COG3247	response to pH
BWP24_09330	COG0668	transmembrane transport
BWP24_09340	COG1404	Belongs to the peptidase S8 family
BWP24_09350	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BWP24_09365	COG0745	RESPONSE REGULATOR receiver
BWP24_09415	COG2199	diguanylate cyclase activity
BWP24_09415	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BWP24_09450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWP24_09465	COG0786	glutamate:sodium symporter activity
BWP24_09485	COG0625	glutathione transferase activity
BWP24_09495	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BWP24_09510	COG2195	Cleaves the N-terminal amino acid of tripeptides
BWP24_09540	COG0813	purine-nucleoside phosphorylase activity
BWP24_09555	COG3706	GGDEF domain
BWP24_09555	COG0745	RESPONSE REGULATOR receiver
BWP24_09565	COG1451	nucleotide metabolic process
BWP24_09575	COG5492	domain, Protein
BWP24_09575	COG4932	domain protein
BWP24_09590	COG2201	protein-glutamate methylesterase activity
BWP24_09660	COG4968	Prepilin-type N-terminal cleavage methylation domain
BWP24_09685	COG0583	DNA-binding transcription factor activity
BWP24_09715	COG4139	cobalamin transport
BWP24_09730	COG2062	phosphohistidine phosphatase, SixA
BWP24_09740	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BWP24_09750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BWP24_09755	COG0702	epimerase
BWP24_09770	COG2925	Exonuclease
BWP24_09780	COG1346	cytolysis
BWP24_09830	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWP24_09835	COG4605	iron ion homeostasis
BWP24_09840	COG4607	ABC-type enterochelin transport system periplasmic component
BWP24_09845	COG4774	siderophore transport
BWP24_09850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BWP24_09855	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BWP24_09865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BWP24_09885	COG3433	isochorismatase activity
BWP24_09885	COG1535	isochorismatase
BWP24_09890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BWP24_09890	COG0072	phenylalanine-tRNA ligase activity
BWP24_09900	COG3706	GGDEF domain
BWP24_09940	COG0251	oxidation-reduction process
BWP24_09980	COG2188	Transcriptional regulator
BWP24_09990	COG0010	Belongs to the arginase family
BWP24_10000	COG2986	histidine ammonia-lyase
BWP24_10045	COG0247	lactate metabolic process
BWP24_10045	COG0277	FAD linked oxidase domain protein
BWP24_10105	COG1643	Atp-dependent helicase
BWP24_10115	COG2949	membrane
BWP24_10120	COG0471	metal ion transport
BWP24_10125	COG3706	GGDEF domain
BWP24_10145	COG0492	ferredoxin-NADP+ reductase activity
BWP24_10150	COG4988	ABC transporter
BWP24_10155	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BWP24_10165	COG2610	gluconate transmembrane transporter activity
BWP24_10170	COG0583	DNA-binding transcription factor activity
BWP24_10175	COG2200	EAL domain
BWP24_10205	COG5001	Diguanylate cyclase
BWP24_10220	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BWP24_10230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWP24_10230	COG4191	Histidine kinase
BWP24_10245	COG3070	regulator of competence-specific genes
BWP24_10255	COG2431	L-lysine efflux transmembrane transporter activity
BWP24_10265	COG0076	glutamate decarboxylase activity
BWP24_10270	COG1737	Transcriptional regulator
BWP24_10280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BWP24_10290	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BWP24_10320	COG4181	ATPase activity
BWP24_10325	COG0534	Mate efflux family protein
BWP24_10330	COG0702	epimerase
BWP24_10335	COG4667	esterase of the alpha-beta hydrolase superfamily
BWP24_10345	COG2814	Major facilitator Superfamily
BWP24_10350	COG1187	pseudouridine synthase activity
BWP24_10355	COG1061	Type III restriction enzyme res subunit
BWP24_10375	COG2199	diguanylate cyclase activity
BWP24_10385	COG0745	RESPONSE REGULATOR receiver
BWP24_10390	COG2205	protein histidine kinase activity
BWP24_10430	COG3313	Fe-S protein
BWP24_10440	COG0659	secondary active sulfate transmembrane transporter activity
BWP24_10465	COG0493	'glutamate synthase
BWP24_10475	COG0398	Pfam SNARE associated Golgi protein
BWP24_10480	COG4134	Bacterial extracellular solute-binding protein
BWP24_10485	COG4135	transport system, permease component
BWP24_10490	COG4136	ATPase activity
BWP24_10495	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BWP24_10505	COG2814	Major facilitator Superfamily
BWP24_10510	COG3604	Transcriptional regulator
BWP24_10515	COG1151	hydroxylamine reductase activity
BWP24_10520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BWP24_10530	COG0564	pseudouridine synthase activity
BWP24_10540	COG0733	neurotransmitter:sodium symporter activity
BWP24_10550	COG0626	cystathionine gamma-synthase activity
BWP24_10555	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BWP24_10575	COG2818	Glycosylase
BWP24_10595	COG1983	PspC domain protein
BWP24_10605	COG1842	Phage shock protein A
BWP24_10610	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BWP24_10620	COG4168	peptide transport system, permease
BWP24_10625	COG4171	peptide transport system, permease
BWP24_10635	COG4172	Belongs to the ABC transporter superfamily
BWP24_10645	COG1227	inorganic diphosphatase activity
BWP24_10660	COG0243	molybdopterin cofactor binding
BWP24_10665	COG3005	denitrification pathway
BWP24_10670	COG4459	periplasmic nitrate reductase
BWP24_10675	COG0390	transport system, permease component
BWP24_10680	COG2116	formate transmembrane transporter activity
BWP24_10705	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BWP24_10710	COG1435	thymidine kinase activity
BWP24_10715	COG0215	cysteine-tRNA ligase activity
BWP24_10720	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BWP24_10725	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BWP24_10735	COG3012	SEC-C Motif Domain Protein
BWP24_10740	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BWP24_10740	COG0140	phosphoribosyl-ATP diphosphatase activity
BWP24_10745	COG0107	imidazoleglycerol-phosphate synthase activity
BWP24_10750	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BWP24_10755	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BWP24_10760	COG0131	Imidazoleglycerol-phosphate dehydratase
BWP24_10760	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BWP24_10770	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BWP24_10785	COG1757	Na H antiporter
BWP24_10795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWP24_10815	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BWP24_10835	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BWP24_10850	COG0300	oxidoreductase activity
BWP24_10870	COG2226	methyltransferase
BWP24_10890	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BWP24_10910	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BWP24_10920	COG1674	ftsk spoiiie
BWP24_10930	COG0686	Belongs to the AlaDH PNT family
BWP24_10940	COG0583	DNA-binding transcription factor activity
BWP24_10965	COG0402	S-adenosylhomocysteine deaminase activity
BWP24_10970	COG4934	collagen metabolic process
BWP24_10990	COG3568	Endonuclease Exonuclease Phosphatase
BWP24_11010	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BWP24_11025	COG1288	antiporter activity
BWP24_11035	COG2186	Transcriptional regulator
BWP24_11045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWP24_11050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BWP24_11080	COG0747	negative chemotaxis
BWP24_11085	COG4608	Belongs to the ABC transporter superfamily
BWP24_11090	COG0444	Belongs to the ABC transporter superfamily
BWP24_11095	COG0534	Mate efflux family protein
BWP24_11105	COG2824	Alkylphosphonate utilization operon protein PhnA
BWP24_11125	COG3119	arylsulfatase activity
BWP24_11165	COG0457	Tetratricopeptide repeat
BWP24_11230	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BWP24_11235	COG4790	Type iii secretion
BWP24_11240	COG4794	Type iii secretion
BWP24_11245	COG4791	protein targeting
BWP24_11250	COG4792	protein secretion
BWP24_11265	COG3177	Filamentation induced by cAMP protein fic
BWP24_11295	COG4669	(LipO)protein
BWP24_11400	COG2205	protein histidine kinase activity
BWP24_11400	COG0784	Response regulator, receiver
BWP24_11410	COG0754	glutathionylspermidine amidase activity
BWP24_11420	COG3766	membrane
BWP24_11435	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BWP24_11440	COG2885	chlorophyll binding
BWP24_11445	COG0823	Involved in the tonB-independent uptake of proteins
BWP24_11460	COG0811	peptide transport
BWP24_11465	COG0824	Thioesterase
BWP24_11475	COG4890	Cyd operon protein YbgT
BWP24_11480	COG1294	oxidase, subunit
BWP24_11485	COG1271	oxidase subunit
BWP24_11495	COG0632	four-way junction helicase activity
BWP24_11500	COG0840	transmembrane signaling receptor activity
BWP24_11515	COG1801	Protein of unknown function DUF72
BWP24_11530	COG0189	ligase activity
BWP24_11530	COG4067	protein conserved in archaea
BWP24_11550	COG0318	PFAM AMP-dependent synthetase and ligase
BWP24_11565	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BWP24_11570	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BWP24_11580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BWP24_11585	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BWP24_11590	COG0745	RESPONSE REGULATOR receiver
BWP24_11605	COG3070	regulator of competence-specific genes
BWP24_11625	COG0297	glycogen (starch) synthase activity
BWP24_11630	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BWP24_11635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BWP24_11665	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BWP24_11670	COG0542	response to heat
BWP24_11680	COG1278	Cold shock
BWP24_11690	COG1187	pseudouridine synthase activity
BWP24_11695	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BWP24_11705	COG1199	ATP-dependent helicase activity
BWP24_11710	COG0730	response to heat
BWP24_11715	COG3923	Primosomal replication protein n
BWP24_11725	COG0708	Exodeoxyribonuclease III
BWP24_11735	COG4215	(ABC) transporter
BWP24_11760	COG1882	Formate acetyltransferase
BWP24_11770	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BWP24_11785	COG2766	serine protein kinase
BWP24_11790	COG2718	Belongs to the UPF0229 family
BWP24_11795	COG2719	SpoVR family
BWP24_11815	COG1132	(ABC) transporter
BWP24_11820	COG2333	competence protein COMEC
BWP24_11820	COG0658	competence protein
BWP24_11830	COG4591	ABC-type transport system involved in lipoprotein release permease component
BWP24_11835	COG1136	(ABC) transporter
BWP24_11840	COG4591	ABC-type transport system involved in lipoprotein release permease component
BWP24_11850	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BWP24_11865	COG1252	NADH dehydrogenase
BWP24_11895	COG0537	adenosine 5'-monophosphoramidase activity
BWP24_11915	COG2217	Heavy metal translocating P-type atpase
BWP24_11925	COG0516	GMP reductase activity
BWP24_11925	COG0517	IMP dehydrogenase activity
BWP24_11930	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BWP24_11935	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BWP24_11940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BWP24_11950	COG3706	GGDEF domain
BWP24_11965	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BWP24_11970	COG1946	Acyl-CoA thioesterase
BWP24_11975	COG1522	sequence-specific DNA binding
BWP24_12000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWP24_12055	COG2855	membrane
BWP24_12060	COG0583	DNA-binding transcription factor activity
BWP24_12065	COG1263	PTS System
BWP24_12065	COG2190	(PTS) system
BWP24_12065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWP24_12075	COG1441	menaquinone biosynthetic process
BWP24_12080	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BWP24_12085	COG0596	Alpha beta hydrolase
BWP24_12095	COG1169	isochorismate synthase
BWP24_12100	COG0436	Aminotransferase
BWP24_12105	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BWP24_12125	COG1555	photosystem II stabilization
BWP24_12130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BWP24_12135	COG0776	regulation of translation
BWP24_12140	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BWP24_12175	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BWP24_12180	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BWP24_12185	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BWP24_12200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BWP24_12205	COG0569	domain protein
BWP24_12210	COG0513	Belongs to the DEAD box helicase family
BWP24_12215	COG1253	flavin adenine dinucleotide binding
BWP24_12220	COG4771	TonB-dependent receptor
BWP24_12225	COG2977	Belongs to the P-Pant transferase superfamily
BWP24_12235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BWP24_12235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BWP24_12240	COG3433	isochorismatase activity
BWP24_12240	COG1535	isochorismatase
BWP24_12245	COG1021	2,3-dihydroxybenzoate-AMP ligase
BWP24_12250	COG1169	isochorismate synthase
BWP24_12260	COG1028	Short-chain dehydrogenase reductase Sdr
BWP24_12295	COG1104	cysteine desulfurase activity
BWP24_12315	COG0556	nucleotide-excision repair
BWP24_12355	COG2852	Protein conserved in bacteria
BWP24_12360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BWP24_12370	COG2951	lytic endotransglycosylase activity
BWP24_12385	COG2894	cell division
BWP24_12390	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BWP24_12395	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BWP24_12400	COG0318	PFAM AMP-dependent synthetase and ligase
BWP24_12405	COG2267	carboxylic ester hydrolase activity
BWP24_12410	COG3065	identical protein binding
BWP24_12420	COG1214	PFAM Peptidase M22, glycoprotease
BWP24_12425	COG1199	ATP-dependent helicase activity
BWP24_12435	COG0788	formyltetrahydrofolate deformylase activity
BWP24_12450	COG3102	Protein conserved in bacteria
BWP24_12480	COG1918	ferrous iron import across plasma membrane
BWP24_12485	COG4977	sequence-specific DNA binding
BWP24_12490	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BWP24_12495	COG1121	(ABC) transporter
BWP24_12500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BWP24_12515	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWP24_12520	COG0567	Dehydrogenase, E1 component
BWP24_12530	COG1053	succinate dehydrogenase
BWP24_12535	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BWP24_12540	COG2009	succinate dehydrogenase
BWP24_12550	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BWP24_12565	COG0033	Phosphoglucomutase
BWP24_12575	COG0596	Alpha beta hydrolase
BWP24_12595	COG0735	belongs to the Fur family
BWP24_12600	COG2165	general secretion pathway protein
BWP24_12610	COG2190	(PTS) system
BWP24_12610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWP24_12610	COG1263	PTS System
BWP24_12615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BWP24_12620	COG1940	carbohydrate kinase activity
BWP24_12620	COG1846	Transcriptional regulator
BWP24_12625	COG4651	solute:proton antiporter activity
BWP24_12625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BWP24_12630	COG0367	asparagine synthase
BWP24_12640	COG3104	oligopeptide transport
BWP24_12645	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BWP24_12660	COG3710	Transcriptional regulator
BWP24_12680	COG0622	Phosphoesterase
BWP24_12710	COG1090	epimerase
BWP24_12715	COG0300	oxidoreductase activity
BWP24_12725	COG3118	belongs to the thioredoxin family
BWP24_12730	COG3118	belongs to the thioredoxin family
BWP24_12730	COG0457	Tetratricopeptide repeat
BWP24_12735	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BWP24_12740	COG1215	transferase activity, transferring glycosyl groups
BWP24_12745	COG1215	transferase activity, transferring glycosyl groups
BWP24_12750	COG1192	Involved in chromosome partitioning
BWP24_12765	COG2194	sulfuric ester hydrolase activity
BWP24_12770	COG0330	HflC and HflK could
BWP24_12805	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BWP24_12810	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWP24_12820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWP24_12825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BWP24_12830	COG2190	(PTS) system
BWP24_12835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWP24_12840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWP24_12850	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWP24_12865	COG1705	Flagellar rod assembly protein muramidase FlgJ
BWP24_12865	COG3951	Flagellar rod assembly protein muramidase FlgJ
BWP24_12870	COG1706	bacterial-type flagellum-dependent cell motility
BWP24_12875	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BWP24_12880	COG4786	Flagellar basal body rod
BWP24_12885	COG4787	bacterial-type flagellum-dependent cell motility
BWP24_12890	COG1749	Flagellar hook protein flgE
BWP24_12895	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BWP24_12900	COG1558	bacterial-type flagellum-dependent cell motility
BWP24_12905	COG1815	bacterial-type flagellum-dependent cell motility
BWP24_12910	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BWP24_12915	COG0784	Response regulator, receiver
BWP24_12915	COG0835	chemotaxis
BWP24_12975	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BWP24_12985	COG2217	Heavy metal translocating P-type atpase
BWP24_12985	COG2608	mercury ion transmembrane transporter activity
BWP24_13025	COG2840	Smr protein MutS2
BWP24_13030	COG1187	pseudouridine synthase activity
BWP24_13035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BWP24_13040	COG0737	Belongs to the 5'-nucleotidase family
BWP24_13050	COG2912	Transglutaminase-like superfamily
BWP24_13055	COG3094	Invasion gene expression up-regulator, SirB
BWP24_13060	COG2890	protein-(glutamine-N5) methyltransferase activity
BWP24_13085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BWP24_13210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWP24_13220	COG1702	phosphate starvation-inducible protein PhoH
BWP24_13230	COG4535	Mg2 and Co2 transporter CorC
BWP24_13235	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BWP24_13240	COG2888	peptidyl-tyrosine sulfation
BWP24_13250	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BWP24_13255	COG1466	dna polymerase III delta subunit
BWP24_13260	COG0799	negative regulation of ribosome biogenesis
BWP24_13270	COG0768	penicillin binding
BWP24_13275	COG0772	Belongs to the SEDS family
BWP24_13280	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BWP24_13285	COG1686	Belongs to the peptidase S11 family
BWP24_13305	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BWP24_13310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BWP24_13325	COG0366	Alpha amylase catalytic
BWP24_13330	COG1263	PTS System
BWP24_13330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWP24_13340	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BWP24_13345	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BWP24_13350	COG2011	ABC-type metal ion transport system permease component
BWP24_13355	COG1464	Belongs to the NlpA lipoprotein family
BWP24_13365	COG0737	Belongs to the 5'-nucleotidase family
BWP24_13370	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
BWP24_13390	COG3706	GGDEF domain
BWP24_13390	COG0745	RESPONSE REGULATOR receiver
BWP24_13395	COG1611	Belongs to the LOG family
BWP24_13415	COG2363	Small membrane protein
BWP24_13425	COG0583	DNA-binding transcription factor activity
BWP24_13440	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BWP24_13450	COG0142	geranyltranstransferase activity
BWP24_13460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BWP24_13465	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BWP24_13490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BWP24_13490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BWP24_13495	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BWP24_13500	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BWP24_13525	COG2252	PERMEase
BWP24_13530	COG2195	Cleaves the N-terminal amino acid of tripeptides
BWP24_13555	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BWP24_13555	COG0047	phosphoribosylformylglycinamidine synthase activity
BWP24_13565	COG0590	tRNA wobble adenosine to inosine editing
BWP24_13575	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BWP24_13615	COG1301	dicarboxylic acid transport
BWP24_13630	COG0497	DNA recombination
BWP24_13635	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BWP24_13640	COG2914	Belongs to the UPF0125 (RnfH) family
BWP24_13645	COG2867	negative regulation of translational initiation
BWP24_13660	COG0583	DNA-binding transcription factor activity
BWP24_13665	COG1289	transmembrane transporter activity
BWP24_13685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BWP24_13690	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BWP24_13695	COG0668	transmembrane transport
BWP24_13715	COG0583	DNA-binding transcription factor activity
BWP24_13725	COG1115	amino acid carrier protein
BWP24_13730	COG1584	GPR1 FUN34 yaaH family protein
BWP24_13740	COG1757	Na H antiporter
BWP24_13750	COG0516	GMP reductase activity
BWP24_13750	COG0517	IMP dehydrogenase activity
BWP24_13765	COG2203	Gaf domain
BWP24_13765	COG2199	diguanylate cyclase activity
BWP24_13780	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BWP24_13785	COG2976	Protein conserved in bacteria
BWP24_13800	COG1426	Protein conserved in bacteria
BWP24_13820	COG2975	iron-sulfur cluster assembly
BWP24_13825	COG0633	Ferredoxin
BWP24_13840	COG0316	Belongs to the HesB IscA family
BWP24_13845	COG0822	iron-sulfur transferase activity
BWP24_13860	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BWP24_13865	COG0483	inositol monophosphate 1-phosphatase activity
BWP24_13870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BWP24_13875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BWP24_13880	COG1862	Preprotein translocase
BWP24_13905	COG0517	IMP dehydrogenase activity
BWP24_13915	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BWP24_13920	COG0583	DNA-binding transcription factor activity
BWP24_13925	COG0450	alkyl hydroperoxide reductase
BWP24_13955	COG0704	Plays a role in the regulation of phosphate uptake
BWP24_13960	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BWP24_13965	COG0581	inorganic phosphate transmembrane transporter activity
BWP24_13970	COG0573	inorganic phosphate transmembrane transporter activity
BWP24_13975	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BWP24_13980	COG0248	Ppx GppA phosphatase
BWP24_13990	COG5002	protein histidine kinase activity
BWP24_13995	COG0745	RESPONSE REGULATOR receiver
BWP24_14015	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BWP24_14075	COG0542	response to heat
BWP24_14085	COG0564	pseudouridine synthase activity
BWP24_14090	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BWP24_14095	COG0741	lytic transglycosylase activity
BWP24_14100	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BWP24_14105	COG1605	Chorismate mutase
BWP24_14105	COG0077	Prephenate dehydratase
BWP24_14110	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BWP24_14125	COG0488	(ABC) transporter
BWP24_14135	COG0739	heme binding
BWP24_14140	COG0287	Prephenate dehydrogenase
BWP24_14140	COG1605	Chorismate mutase
BWP24_14145	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BWP24_14150	COG1472	Belongs to the glycosyl hydrolase 3 family
BWP24_14155	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BWP24_14175	COG1966	Carbon starvation protein
BWP24_14180	COG3275	phosphorelay sensor kinase activity
BWP24_14185	COG3279	Response regulator of the LytR AlgR family
BWP24_14190	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BWP24_14195	COG1047	Peptidyl-prolyl cis-trans
BWP24_14210	COG0196	riboflavin kinase activity
BWP24_14215	COG0728	peptidoglycan biosynthetic process
BWP24_14220	COG0268	Binds directly to 16S ribosomal RNA
BWP24_14225	COG0640	Transcriptional regulator
BWP24_14230	COG0583	DNA-binding transcription factor activity
BWP24_14235	COG1283	sodium-dependent phosphate transmembrane transporter activity
BWP24_14250	COG0730	response to heat
BWP24_14275	COG0667	Aldo Keto reductase
BWP24_14300	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BWP24_14305	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BWP24_14315	COG0716	FMN binding
BWP24_14330	COG0513	Belongs to the DEAD box helicase family
BWP24_14340	COG3022	response to hydroperoxide
BWP24_14345	COG1115	amino acid carrier protein
BWP24_14380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BWP24_14385	COG0083	homoserine kinase activity
BWP24_14400	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BWP24_14410	COG0745	RESPONSE REGULATOR receiver
BWP24_14420	COG5002	protein histidine kinase activity
BWP24_14420	COG2198	Histidine kinase
BWP24_14420	COG0784	Response regulator, receiver
BWP24_14430	COG5001	Diguanylate cyclase
BWP24_14430	COG4251	negative regulation of phosphorylation
BWP24_14430	COG2203	Gaf domain
BWP24_14430	COG3706	GGDEF domain
BWP24_14435	COG1242	4 iron, 4 sulfur cluster binding
BWP24_14440	COG0067	glutamate synthase
BWP24_14440	COG0069	glutamate synthase activity
BWP24_14440	COG0070	glutamate synthase
BWP24_14450	COG0067	glutamate synthase
BWP24_14450	COG0070	glutamate synthase
BWP24_14450	COG0069	glutamate synthase activity
BWP24_14455	COG0493	'glutamate synthase
BWP24_14480	COG2860	membrane
BWP24_14485	COG0583	DNA-binding transcription factor activity
BWP24_14490	COG0730	response to heat
BWP24_14505	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BWP24_14510	COG0505	Belongs to the CarA family
BWP24_14520	COG0494	nUDIX hydrolase
BWP24_14540	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BWP24_14545	COG0849	cell division
BWP24_14550	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BWP24_14565	COG0772	Belongs to the SEDS family
BWP24_14580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BWP24_14585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BWP24_14590	COG0768	penicillin binding
BWP24_14595	COG3116	cell division
BWP24_14610	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BWP24_14625	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BWP24_14630	COG2823	Periplasmic or secreted lipoprotein
BWP24_14635	COG2969	positive regulation of protein catabolic process
BWP24_14640	COG0625	glutathione transferase activity
BWP24_14645	COG2857	Cytochrome c1
BWP24_14650	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BWP24_14655	COG0723	plastoquinol--plastocyanin reductase activity
BWP24_14670	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BWP24_14675	COG3105	Protein conserved in bacteria
BWP24_14680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BWP24_14685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BWP24_14690	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BWP24_14695	COG0187	DNA topoisomerase II activity
BWP24_14700	COG3150	esterase
BWP24_14710	COG3151	Protein conserved in bacteria
BWP24_14715	COG0494	nUDIX hydrolase
BWP24_14720	COG1538	Outer membrane efflux protein
BWP24_14730	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BWP24_14740	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BWP24_14745	COG3025	triphosphatase activity
BWP24_14750	COG1392	Phosphate transport regulator
BWP24_14755	COG0306	phosphate transporter
BWP24_14760	COG4991	sh3 domain protein
BWP24_14765	COG0405	Gamma-glutamyltransferase
BWP24_14775	COG3409	Peptidoglycan-binding domain 1 protein
BWP24_14775	COG3267	Type II secretory pathway component ExeA
BWP24_14790	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BWP24_14795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BWP24_14805	COG0596	Alpha beta hydrolase
BWP24_14810	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BWP24_14815	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BWP24_14820	COG1610	YqeY-like protein
BWP24_14825	COG0358	DNA primase activity
BWP24_14830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BWP24_14865	COG2213	PTS system mannitol-specific
BWP24_14865	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWP24_14875	COG3722	fumarate hydratase activity
BWP24_14880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BWP24_14885	COG5002	protein histidine kinase activity
BWP24_14905	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BWP24_14910	COG1349	DNA-binding transcription factor activity
BWP24_14915	COG0469	pyruvate kinase activity
BWP24_14925	COG3706	GGDEF domain
BWP24_14930	COG0440	acetolactate synthase activity
BWP24_14935	COG0028	Belongs to the TPP enzyme family
BWP24_14940	COG1022	Amp-dependent synthetase and ligase
BWP24_14945	COG0583	DNA-binding transcription factor activity
BWP24_14970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BWP24_14975	COG0473	3-isopropylmalate dehydrogenase activity
BWP24_14995	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BWP24_15000	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BWP24_15005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BWP24_15010	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BWP24_15035	COG3610	response to peptide
BWP24_15040	COG2966	Psort location CytoplasmicMembrane, score
BWP24_15055	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BWP24_15060	COG0142	geranyltranstransferase activity
BWP24_15095	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BWP24_15100	COG1178	ABC-type Fe3 transport system permease component
BWP24_15105	COG4143	(ABC) transporter
BWP24_15110	COG0163	prenyltransferase activity
BWP24_15115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BWP24_15125	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BWP24_15140	COG2105	PFAM AIG2 family protein
BWP24_15150	COG0729	surface antigen
BWP24_15155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWP24_15165	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BWP24_15180	COG1136	(ABC) transporter
BWP24_15200	COG0529	Catalyzes the synthesis of activated sulfate
BWP24_15205	COG3273	potassium ion transport
BWP24_15205	COG0471	metal ion transport
BWP24_15220	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BWP24_15220	COG1648	precorrin-2 dehydrogenase activity
BWP24_15225	COG0737	Belongs to the 5'-nucleotidase family
BWP24_15235	COG0513	Belongs to the DEAD box helicase family
BWP24_15240	COG2153	protein acetylation
BWP24_15255	COG0545	Peptidyl-prolyl cis-trans isomerase
BWP24_15265	COG0203	ribosomal protein L17
BWP24_15270	COG0202	RNA polymerase activity
BWP24_15280	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BWP24_15285	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BWP24_15295	COG0201	protein transport
BWP24_15305	COG1841	ribosomal large subunit assembly
BWP24_15390	COG0088	Forms part of the polypeptide exit tunnel
BWP24_15410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BWP24_15415	COG1609	Transcriptional regulator
BWP24_15435	COG1575	Belongs to the MenA family. Type 1 subfamily
BWP24_15440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BWP24_15450	COG1494	fructose-1,6-bisphosphatase
BWP24_15475	COG0149	triose-phosphate isomerase activity
BWP24_15510	COG1216	Glycosyl transferase, family 2
BWP24_15535	COG1215	transferase activity, transferring glycosyl groups
BWP24_15540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BWP24_15545	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BWP24_15550	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BWP24_15555	COG1215	transferase activity, transferring glycosyl groups
BWP24_15580	COG2244	polysaccharide biosynthetic process
BWP24_15585	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BWP24_15635	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BWP24_15645	COG1560	Kdo2-lipid A biosynthetic process
BWP24_15655	COG0438	transferase activity, transferring glycosyl groups
BWP24_15660	COG1519	Transferase
BWP24_15665	COG1442	glycosyl transferase family 8
BWP24_15665	COG1216	Glycosyl transferase, family 2
BWP24_15670	COG5039	Polysaccharide pyruvyl transferase
BWP24_15675	COG3642	lipopolysaccharide core region biosynthetic process
BWP24_15680	COG0859	PFAM glycosyl transferase family 9
BWP24_15690	COG0438	transferase activity, transferring glycosyl groups
BWP24_15705	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BWP24_15740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BWP24_15750	COG1560	Kdo2-lipid A biosynthetic process
BWP24_15760	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BWP24_15765	COG1561	YicC-like family, N-terminal region
BWP24_15785	COG4608	Belongs to the ABC transporter superfamily
BWP24_15790	COG0444	Belongs to the ABC transporter superfamily
BWP24_15795	COG0747	negative chemotaxis
BWP24_15800	COG4239	(ABC) transporter, permease
BWP24_15805	COG4174	ABC transporter (Permease)
BWP24_15810	COG4206	TonB-dependent receptor
BWP24_15825	COG0811	peptide transport
BWP24_15830	COG0848	biopolymer transport protein
BWP24_15845	COG0194	GDP metabolic process
BWP24_15850	COG1758	RNA polymerase activity
BWP24_15855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BWP24_15860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BWP24_15865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BWP24_15875	COG2233	PERMEase
BWP24_15880	COG2205	protein histidine kinase activity
BWP24_15885	COG0745	RESPONSE REGULATOR receiver
BWP24_15890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BWP24_15900	COG2183	response to ionizing radiation
BWP24_15915	COG1040	competence protein
BWP24_15925	COG0494	nUDIX hydrolase
BWP24_15930	COG1218	3'(2'),5'-bisphosphate nucleotidase
BWP24_15940	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BWP24_15945	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BWP24_15950	COG3156	type II secretion system protein K
BWP24_15955	COG4795	General secretion pathway protein
BWP24_15960	COG2165	general secretion pathway protein
BWP24_15965	COG2165	general secretion pathway protein
BWP24_15970	COG2165	general secretion pathway protein
BWP24_15975	COG1459	type II secretion system
BWP24_15980	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BWP24_15990	COG3031	protein transport across the cell outer membrane
BWP24_15995	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BWP24_16015	COG0456	acetyltransferase
BWP24_16020	COG1490	D-aminoacyl-tRNA deacylase activity
BWP24_16050	COG0174	glutamine synthetase
BWP24_16060	COG3852	Histidine kinase
BWP24_16065	COG2204	response regulator
BWP24_16070	COG5001	Diguanylate cyclase
BWP24_16070	COG3300	MHYT domain
BWP24_16075	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BWP24_16080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BWP24_16110	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BWP24_16115	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BWP24_16115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BWP24_16135	COG0084	hydrolase, TatD family'
BWP24_16140	COG0805	protein transport
BWP24_16160	COG3165	ubiquinone biosynthetic process from chorismate
BWP24_16170	COG1322	Protein conserved in bacteria
BWP24_16185	COG1910	domain protein
BWP24_16205	COG2081	HI0933 family
BWP24_16215	COG1528	Iron-storage protein
BWP24_16220	COG0589	response to stress
BWP24_16225	COG0697	spore germination
BWP24_16240	COG5001	Diguanylate cyclase
BWP24_16240	COG5002	protein histidine kinase activity
BWP24_16245	COG1522	sequence-specific DNA binding
BWP24_16260	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BWP24_16270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWP24_16315	COG3550	peptidyl-serine autophosphorylation
BWP24_16360	COG0800	Aldolase
BWP24_16365	COG2610	gluconate transmembrane transporter activity
BWP24_16370	COG3265	gluconokinase activity
BWP24_16375	COG0129	dihydroxy-acid dehydratase activity
BWP24_16385	COG2076	Multidrug Resistance protein
BWP24_16390	COG0583	DNA-binding transcription factor activity
BWP24_16395	COG1609	Transcriptional regulator
BWP24_16400	COG0515	serine threonine protein kinase
BWP24_16430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWP24_16440	COG4166	transmembrane transport
BWP24_16445	COG4172	Belongs to the ABC transporter superfamily
BWP24_16495	COG1309	transcriptional regulator
BWP24_16500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BWP24_16505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWP24_16510	COG2960	long-chain fatty acid transporting porin activity
BWP24_16520	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BWP24_16525	COG0583	DNA-binding transcription factor activity
BWP24_16540	COG0444	Belongs to the ABC transporter superfamily
BWP24_16545	COG4608	Belongs to the ABC transporter superfamily
BWP24_16570	COG1444	tRNA N-acetyltransferase activity
BWP24_16595	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BWP24_16600	COG1263	PTS System
BWP24_16600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWP24_16605	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BWP24_16620	COG4166	transmembrane transport
BWP24_16625	COG0655	NAD(P)H dehydrogenase (quinone) activity
BWP24_16755	COG1132	(ABC) transporter
BWP24_16795	COG0800	Aldolase
BWP24_16800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWP24_16805	COG1904	glucuronate isomerase
BWP24_16810	COG0246	Mannitol dehydrogenase
BWP24_16820	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BWP24_16830	COG2186	Transcriptional regulator
BWP24_16835	COG1312	Catalyzes the dehydration of D-mannonate
BWP24_16840	COG0583	DNA-binding transcription factor activity
BWP24_16855	COG0513	Belongs to the DEAD box helicase family
BWP24_16860	COG3713	MltA-interacting MipA family protein
BWP24_16870	COG2153	protein acetylation
BWP24_16875	COG2258	MOSC domain
BWP24_16890	COG0544	peptidyl-prolyl cis-trans isomerase activity
BWP24_16895	COG1522	sequence-specific DNA binding
BWP24_16910	COG1486	melibiose metabolic process
BWP24_16915	COG0583	DNA-binding transcription factor activity
BWP24_16930	COG1349	DNA-binding transcription factor activity
BWP24_16935	COG2084	Dehydrogenase
BWP24_16940	COG3395	kinase activity
BWP24_16945	COG0235	Class ii aldolase
BWP24_16950	COG3622	Belongs to the hyi family
BWP24_16955	COG2610	gluconate transmembrane transporter activity
BWP24_17015	COG3634	alkyl hydroperoxide reductase activity
BWP24_17020	COG0450	alkyl hydroperoxide reductase
BWP24_17025	COG1846	Transcriptional regulator
BWP24_17030	COG1764	response to oxidative stress
BWP24_17070	COG1136	(ABC) transporter
BWP24_17075	COG1335	isochorismatase
BWP24_17090	COG0463	Glycosyl transferase, family 2
BWP24_17125	COG0840	transmembrane signaling receptor activity
BWP24_17130	COG0612	Peptidase, M16
BWP24_17155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWP24_17160	COG0383	alpha-mannosidase activity
BWP24_17170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWP24_17170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWP24_17170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWP24_17195	COG3188	usher protein
BWP24_17200	COG3121	Chaperone
BWP24_17225	COG2188	Transcriptional regulator
BWP24_17235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWP24_17235	COG1263	PTS System
BWP24_17235	COG2190	(PTS) system
BWP24_17240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWP24_17245	COG0800	Aldolase
BWP24_17260	COG0739	heme binding
BWP24_17290	COG2814	Major facilitator Superfamily
BWP24_17300	COG1609	Transcriptional regulator
BWP24_17325	COG1760	l-serine dehydratase
BWP24_17335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BWP24_17355	COG2199	diguanylate cyclase activity
BWP24_17355	COG2203	Gaf domain
BWP24_17365	COG4580	involved in the transport of maltose and maltodextrins
BWP24_17385	COG2356	endonuclease I
BWP24_17405	COG1982	Orn Lys Arg decarboxylase major
BWP24_17410	COG0531	amino acid
BWP24_17435	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BWP24_17440	COG0183	Belongs to the thiolase family
BWP24_17460	COG2814	Major facilitator Superfamily
BWP24_17460	COG0477	Major facilitator Superfamily
BWP24_17470	COG3962	Belongs to the TPP enzyme family
BWP24_17475	COG0673	inositol 2-dehydrogenase activity
BWP24_17480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWP24_17505	COG0673	inositol 2-dehydrogenase activity
BWP24_17510	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BWP24_17515	COG1162	GTPase activity
BWP24_17530	COG1999	signal sequence binding
BWP24_17555	COG0058	SHG alpha-glucan phosphorylase activity
BWP24_17560	COG1640	4-alpha-glucanotransferase
BWP24_17565	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BWP24_17570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BWP24_17575	COG0366	Alpha amylase catalytic
BWP24_17590	COG3366	ferrous iron transmembrane transporter activity
BWP24_17595	COG0700	Nucleoside recognition
BWP24_17600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BWP24_17605	COG3339	Conserved Protein
BWP24_17615	COG1301	dicarboxylic acid transport
BWP24_17650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BWP24_17655	COG1596	polysaccharide export
BWP24_17675	COG4667	esterase of the alpha-beta hydrolase superfamily
BWP24_17685	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BWP24_17690	COG0415	Belongs to the DNA photolyase family
BWP24_17715	COG1686	Belongs to the peptidase S11 family
BWP24_17725	COG0583	DNA-binding transcription factor activity
BWP24_17730	COG4628	conserved protein (DUF2132)
BWP24_17740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BWP24_17755	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BWP24_17760	COG0628	permease
BWP24_17800	COG2988	succinylglutamate desuccinylase activity
BWP24_17810	COG2814	Major facilitator Superfamily
BWP24_17820	COG0454	-acetyltransferase
BWP24_17830	COG0745	RESPONSE REGULATOR receiver
BWP24_17835	COG2205	protein histidine kinase activity
BWP24_17850	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BWP24_17855	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BWP24_17900	COG0251	oxidation-reduction process
BWP24_17910	COG1294	oxidase, subunit
BWP24_17915	COG1271	oxidase subunit
BWP24_17930	COG3220	belongs to the UPF0276 family
BWP24_17950	COG0384	phenazine biosynthesis protein PhzF
BWP24_17955	COG0346	lactoylglutathione lyase activity
BWP24_17970	COG0488	(ABC) transporter
BWP24_17975	COG4628	conserved protein (DUF2132)
BWP24_17990	COG0583	DNA-binding transcription factor activity
BWP24_18000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWP24_18005	COG1280	lysine exporter protein (LysE YggA)
BWP24_18035	COG0737	Belongs to the 5'-nucleotidase family
BWP24_18040	COG3537	Alpha-1,2-mannosidase
BWP24_18045	COG3537	Alpha-1,2-mannosidase
BWP24_18055	COG3537	Alpha-1,2-mannosidase
BWP24_18060	COG3537	Alpha-1,2-mannosidase
BWP24_18065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWP24_18080	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWP24_18080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWP24_18085	COG0346	lactoylglutathione lyase activity
BWP24_18090	COG1349	DNA-binding transcription factor activity
BWP24_18120	COG1335	isochorismatase
BWP24_18155	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BWP24_18165	COG0583	DNA-binding transcription factor activity
BWP24_18170	COG0589	response to stress
BWP24_18190	COG3448	diguanylate cyclase activity
BWP24_18190	COG4175	Glycine betaine
BWP24_18195	COG4176	ABC-type proline glycine betaine transport system permease component
BWP24_18205	COG1342	Belongs to the UPF0251 family
BWP24_18225	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BWP24_18235	COG4948	Mandelate Racemase Muconate Lactonizing
BWP24_18275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BWP24_18285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWP24_18350	COG4964	Belongs to the GSP D family
BWP24_18420	COG0318	PFAM AMP-dependent synthetase and ligase
BWP24_18425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BWP24_18435	COG2197	response regulator
BWP24_18455	COG0786	glutamate:sodium symporter activity
BWP24_18460	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BWP24_18465	COG1538	Outer membrane efflux protein
BWP24_18475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BWP24_18480	COG0583	DNA-binding transcription factor activity
BWP24_18515	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BWP24_18520	COG2197	response regulator
BWP24_18530	COG0574	Belongs to the PEP-utilizing enzyme family
BWP24_18530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BWP24_18540	COG0252	asparaginase activity
BWP24_18560	COG0583	DNA-binding transcription factor activity
BWP24_18570	COG2321	neutral zinc metallopeptidase
BWP24_18575	COG3122	Protein conserved in bacteria
BWP24_18590	COG2255	four-way junction helicase activity
BWP24_18600	COG3853	Toxic anion resistance protein (TelA)
BWP24_18610	COG1902	pentaerythritol trinitrate reductase activity
BWP24_18630	COG0583	DNA-binding transcription factor activity
BWP24_18640	COG0513	Belongs to the DEAD box helicase family
BWP24_18685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWP24_18710	COG3746	phosphate-selective porin O and P
BWP24_18735	COG1028	Short-chain dehydrogenase reductase Sdr
BWP24_18780	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BWP24_18790	COG0625	glutathione transferase activity
BWP24_18795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BWP24_18800	COG1686	Belongs to the peptidase S11 family
BWP24_18810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BWP24_18835	COG0745	RESPONSE REGULATOR receiver
BWP24_18835	COG3706	GGDEF domain
BWP24_18840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BWP24_18855	COG1278	Cold shock
BWP24_18860	COG1741	Belongs to the pirin family
BWP24_18865	COG4667	esterase of the alpha-beta hydrolase superfamily
BWP24_18875	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BWP24_18885	COG0523	cobalamin synthesis protein
BWP24_18895	COG1846	Transcriptional regulator
BWP24_18910	COG3842	ATPase activity
BWP24_18915	COG0395	ABC-type sugar transport system, permease component
BWP24_18920	COG1175	transmembrane transport
BWP24_18930	COG0584	glycerophosphoryl diester phosphodiesterase
BWP24_18940	COG0589	response to stress
BWP24_18955	COG1505	serine-type exopeptidase activity
BWP24_18965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BWP24_18975	COG2067	long-chain fatty acid transport protein
BWP24_18985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWP24_18990	COG1858	cytochrome C peroxidase
BWP24_19005	COG0494	nUDIX hydrolase
BWP24_19050	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWP24_19070	COG3383	formate dehydrogenase (NAD+) activity
BWP24_19090	COG0842	Transport permease protein
BWP24_19095	COG1131	(ABC) transporter
BWP24_19105	COG0840	transmembrane signaling receptor activity
BWP24_19120	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BWP24_19130	COG4145	pantothenate transmembrane transporter activity
BWP24_19135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWP24_19140	COG0800	Aldolase
BWP24_19150	COG2706	6-phosphogluconolactonase activity
BWP24_19155	COG0251	oxidation-reduction process
BWP24_19160	COG1881	PFAM PEBP family protein
BWP24_19175	COG0798	PFAM Bile acid sodium symporter
BWP24_19190	COG1733	regulation of RNA biosynthetic process
BWP24_19200	COG0747	negative chemotaxis
BWP24_19205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWP24_19210	COG2213	PTS system mannitol-specific
BWP24_19215	COG1063	alcohol dehydrogenase
BWP24_19225	COG1072	(Pantothenic acid kinase))
BWP24_19230	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BWP24_19250	COG0814	amino acid
BWP24_19285	COG0739	heme binding
BWP24_19290	COG5001	Diguanylate cyclase
BWP24_19295	COG0583	DNA-binding transcription factor activity
BWP24_19300	COG2814	Major facilitator Superfamily
BWP24_19315	COG0697	spore germination
BWP24_19330	COG0179	Fumarylacetoacetate (FAA) hydrolase
BWP24_19350	COG1280	lysine exporter protein (LysE YggA)
BWP24_19360	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BWP24_19370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BWP24_19375	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BWP24_19400	COG1612	heme a metabolic process
BWP24_19415	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BWP24_19420	COG2814	Major facilitator Superfamily
BWP24_19425	COG0840	transmembrane signaling receptor activity
BWP24_19430	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BWP24_19460	COG2897	thiosulfate sulfurtransferase activity
BWP24_19515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BWP24_19530	COG1914	H( )-stimulated, divalent metal cation uptake system
BWP24_19555	COG4989	oxidoreductase activity
BWP24_19570	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BWP24_19570	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BWP24_19590	COG1073	alpha beta
BWP24_19595	COG0583	DNA-binding transcription factor activity
BWP24_19615	COG4964	Belongs to the GSP D family
BWP24_19625	COG0455	bacterial-type flagellum organization
BWP24_19665	COG2885	chlorophyll binding
BWP24_19695	COG3706	GGDEF domain
BWP24_19720	COG4176	ABC-type proline glycine betaine transport system permease component
BWP24_19725	COG0517	IMP dehydrogenase activity
BWP24_19725	COG4175	Glycine betaine
BWP24_19735	COG0330	HflC and HflK could
BWP24_19750	COG2203	Gaf domain
BWP24_19750	COG3706	GGDEF domain
BWP24_19750	COG4251	negative regulation of phosphorylation
BWP24_19750	COG5001	Diguanylate cyclase
BWP24_19765	COG2205	protein histidine kinase activity
BWP24_19765	COG0784	Response regulator, receiver
BWP24_19810	COG0586	Pfam SNARE associated Golgi protein
BWP24_19835	COG1051	belongs to the nudix hydrolase family
BWP24_19840	COG1794	racemase activity, acting on amino acids and derivatives
BWP24_19845	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BWP24_19850	COG5001	Diguanylate cyclase
BWP24_19860	COG1129	ABC transporter
BWP24_19865	COG1172	Belongs to the binding-protein-dependent transport system permease family
BWP24_19870	COG1879	ABC-type sugar transport system periplasmic component
BWP24_19875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWP24_19880	COG1609	Transcriptional regulator
BWP24_19895	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BWP24_19910	COG4607	ABC-type enterochelin transport system periplasmic component
BWP24_19915	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWP24_19920	COG4605	iron ion homeostasis
BWP24_19925	COG4604	ABC transporter, ATP-binding protein
BWP24_19930	COG0789	Transcriptional regulator
BWP24_19955	COG1289	transmembrane transporter activity
BWP24_19960	COG0210	DNA helicase
BWP24_19970	COG1879	ABC-type sugar transport system periplasmic component
BWP24_19975	COG2198	Histidine kinase
BWP24_19975	COG2205	protein histidine kinase activity
BWP24_19975	COG0784	Response regulator, receiver
BWP24_20005	COG3119	arylsulfatase activity
BWP24_20010	COG3119	arylsulfatase activity
BWP24_20015	COG3063	Type IV pilus biogenesis stability protein PilW
BWP24_20020	COG0714	Associated with various cellular activities
BWP24_20080	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BWP24_20090	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BWP24_20100	COG0583	DNA-binding transcription factor activity
BWP24_20105	COG1597	lipid kinase activity
BWP24_20110	COG3111	PFAM Bacterial OB fold (BOF) protein
BWP24_20130	COG0641	radical SAM
BWP24_20155	COG0501	Belongs to the peptidase M48B family
BWP24_20160	COG1704	LemA family
BWP24_20165	COG3069	C4-dicarboxylate transmembrane transporter activity
BWP24_20195	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BWP24_20200	COG0739	heme binding
BWP24_20250	COG3501	Rhs element vgr protein
BWP24_20275	COG0515	serine threonine protein kinase
BWP24_20310	COG1522	sequence-specific DNA binding
BWP24_20380	COG4771	TonB-dependent receptor
BWP24_20395	COG2205	protein histidine kinase activity
BWP24_20395	COG0784	Response regulator, receiver
BWP24_20400	COG3300	MHYT domain
BWP24_20400	COG5001	Diguanylate cyclase
BWP24_20405	COG2197	response regulator
BWP24_20410	COG3706	GGDEF domain
BWP24_20420	COG2197	response regulator
BWP24_20425	COG0778	Nitroreductase
BWP24_20435	COG0784	Response regulator, receiver
BWP24_20435	COG0835	chemotaxis
BWP24_20450	COG2962	Rard protein
BWP24_20465	COG0671	phosphoesterase, PA-phosphatase related
BWP24_20485	COG2076	Multidrug Resistance protein
BWP24_20525	COG1234	tRNA 3'-trailer cleavage
BWP24_20535	COG0069	glutamate synthase activity
BWP24_20535	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BWP24_20550	COG2755	lipolytic protein G-D-S-L family
BWP24_20550	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BWP24_20560	COG1902	pentaerythritol trinitrate reductase activity
BWP24_20565	COG0346	lactoylglutathione lyase activity
BWP24_20595	COG0515	serine threonine protein kinase
BWP24_20595	COG2815	serine threonine protein kinase
BWP24_20630	COG0631	protein serine/threonine phosphatase activity
BWP24_20685	COG3501	Rhs element vgr protein
BWP24_20725	COG0420	3'-5' exonuclease activity
BWP24_20730	COG0419	ATPase involved in DNA repair
BWP24_20740	COG3469	chitinase activity
BWP24_20770	COG3040	lipid binding
BWP24_20780	COG2814	Major facilitator Superfamily
BWP24_20790	COG1288	antiporter activity
BWP24_20800	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BWP24_20815	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BWP24_20830	COG0583	DNA-binding transcription factor activity
BWP24_20835	COG0277	FAD linked oxidase domain protein
BWP24_20845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BWP24_20920	COG2199	diguanylate cyclase activity
BWP24_20930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BWP24_20935	COG2146	nitrite reductase [NAD(P)H] activity
BWP24_20940	COG2116	formate transmembrane transporter activity
BWP24_20960	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BWP24_20985	COG0534	Mate efflux family protein
BWP24_20995	COG2814	Major facilitator Superfamily
BWP24_21000	COG3118	belongs to the thioredoxin family
BWP24_21005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BWP24_21030	COG1566	PFAM secretion protein HlyD family protein
BWP24_21040	COG0628	permease
BWP24_21050	COG1482	cell wall glycoprotein biosynthetic process
BWP24_21055	COG2271	Major facilitator Superfamily
BWP24_21060	COG3851	Histidine kinase
BWP24_21065	COG2197	response regulator
BWP24_21130	COG1328	CTP reductase activity
BWP24_21135	COG0602	queuosine metabolic process
BWP24_21140	COG0534	Mate efflux family protein
BWP24_21165	COG3111	PFAM Bacterial OB fold (BOF) protein
BWP24_21175	COG0725	ABC transporter, periplasmic molybdate-binding protein
BWP24_21180	COG4149	molybdate abc transporter
BWP24_21185	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BWP24_21195	COG2203	Gaf domain
BWP24_21195	COG3706	GGDEF domain
BWP24_21195	COG4251	negative regulation of phosphorylation
BWP24_21195	COG5001	Diguanylate cyclase
BWP24_21200	COG3706	GGDEF domain
BWP24_21200	COG0745	RESPONSE REGULATOR receiver
BWP24_21215	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BWP24_21220	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BWP24_21245	COG3140	Belongs to the UPF0181 family
BWP24_21270	COG2801	Transposase and inactivated derivatives
BWP24_21290	COG4128	Pfam Zonular occludens toxin
BWP24_21340	COG2801	Transposase and inactivated derivatives
BWP24_21395	COG0023	Translation Initiation Factor
BWP24_21415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWP24_21415	COG1042	CoA-binding domain protein
BWP24_21415	COG0045	succinate-CoA ligase (ADP-forming) activity
BWP24_21420	COG0583	DNA-binding transcription factor activity
BWP24_21430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BWP24_21435	COG5002	protein histidine kinase activity
BWP24_21435	COG5001	Diguanylate cyclase
BWP24_21435	COG3447	MASE1 domain protein
BWP24_21450	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BWP24_21465	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BWP24_21470	COG4181	ATPase activity
BWP24_21480	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BWP24_21485	COG3300	MHYT domain
BWP24_21485	COG5001	Diguanylate cyclase
BWP24_21495	COG0484	heat shock protein binding
BWP24_21530	COG2050	protein possibly involved in aromatic compounds catabolism
BWP24_21535	COG0501	Belongs to the peptidase M48B family
BWP24_21545	COG2067	long-chain fatty acid transport protein
BWP24_21550	COG2267	carboxylic ester hydrolase activity
BWP24_21565	COG1410	methionine synthase
BWP24_21565	COG0646	methionine synthase
BWP24_21575	COG0861	Integral membrane protein TerC family
BWP24_21580	COG0737	Belongs to the 5'-nucleotidase family
BWP24_21585	COG3593	DNA synthesis involved in DNA repair
BWP24_21595	COG0583	DNA-binding transcription factor activity
BWP24_21605	COG2116	formate transmembrane transporter activity
BWP24_21615	COG3038	cytochrome b561
BWP24_21630	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BWP24_21635	COG0513	Belongs to the DEAD box helicase family
BWP24_21640	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
BWP24_21655	COG0546	phosphoglycolate phosphatase activity
BWP24_21660	COG0784	Response regulator, receiver
BWP24_21660	COG3437	response regulator, receiver
BWP24_21675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWP24_21685	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BWP24_21695	COG2207	Transcriptional regulator
BWP24_21700	COG1979	alcohol dehydrogenase
BWP24_21710	COG1126	abc transporter atp-binding protein
BWP24_21715	COG0765	amino acid transport
BWP24_21720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWP24_21725	COG0765	amino acid transport
BWP24_21730	COG2203	Gaf domain
BWP24_21730	COG2200	EAL domain
BWP24_21730	COG2199	diguanylate cyclase activity
BWP24_21745	COG1609	Transcriptional regulator
BWP24_21750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWP24_21750	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWP24_21755	COG1105	Belongs to the carbohydrate kinase PfkB family
BWP24_21760	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWP24_21760	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWP24_21760	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BWP24_21775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BWP24_21780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BWP24_21790	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BWP24_21800	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BWP24_21875	COG4977	sequence-specific DNA binding
BWP24_21895	COG0641	radical SAM
BWP24_21905	COG3119	arylsulfatase activity
BWP24_21930	COG0583	DNA-binding transcription factor activity
BWP24_21945	COG5640	endopeptidase activity
BWP24_21955	COG1132	(ABC) transporter
BWP24_22000	COG2814	Major facilitator Superfamily
BWP24_22080	COG3706	GGDEF domain
BWP24_22080	COG0745	RESPONSE REGULATOR receiver
BWP24_22085	COG0628	permease
BWP24_22115	COG0739	heme binding
BWP24_22125	COG1902	pentaerythritol trinitrate reductase activity
BWP24_22135	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BWP24_22170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BWP24_22170	COG2146	nitrite reductase [NAD(P)H] activity
BWP24_22175	COG1116	anion transmembrane transporter activity
BWP24_22180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BWP24_22185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BWP24_22185	COG1116	anion transmembrane transporter activity
BWP24_22210	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BWP24_22210	COG1648	precorrin-2 dehydrogenase activity
BWP24_22215	COG0243	molybdopterin cofactor binding
BWP24_22225	COG5001	Diguanylate cyclase
BWP24_22225	COG5002	protein histidine kinase activity
BWP24_22230	COG0814	amino acid
BWP24_22235	COG3706	GGDEF domain
BWP24_22255	COG1785	Belongs to the alkaline phosphatase family
BWP24_22270	COG0745	RESPONSE REGULATOR receiver
BWP24_22310	COG0443	Heat shock 70 kDa protein
BWP24_22355	COG2200	EAL domain
BWP24_22380	COG4160	amino acid transport
BWP24_22385	COG4215	(ABC) transporter
BWP24_22390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWP24_22395	COG1126	abc transporter atp-binding protein
BWP24_22455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BWP24_22465	COG1012	belongs to the aldehyde dehydrogenase family
BWP24_22480	COG0446	pyridine nucleotide-disulphide oxidoreductase
BWP24_22480	COG1902	pentaerythritol trinitrate reductase activity
BWP24_22490	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BWP24_22495	COG1845	cytochrome c oxidase, subunit III
BWP24_22500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BWP24_22505	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BWP24_22510	COG1028	Short-chain dehydrogenase reductase Sdr
BWP24_22520	COG1024	Enoyl-CoA hydratase
BWP24_22525	COG1024	Enoyl-CoA hydratase
BWP24_22540	COG0183	Belongs to the thiolase family
BWP24_22550	COG1960	acyl-CoA dehydrogenase activity
BWP24_22555	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BWP24_22560	COG1024	Enoyl-CoA hydratase
BWP24_22600	COG3278	Belongs to the heme-copper respiratory oxidase family
BWP24_22620	COG1752	Esterase of the alpha-beta hydrolase superfamily
BWP24_22630	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BWP24_22650	COG3550	peptidyl-serine autophosphorylation
BWP24_22655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BWP24_22705	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BWP24_22710	COG0840	transmembrane signaling receptor activity
BWP24_22715	COG4580	involved in the transport of maltose and maltodextrins
BWP24_22720	COG1874	Beta-galactosidase
BWP24_22730	COG3833	ABC-type maltose transport systems, permease component
BWP24_22735	COG1175	transmembrane transport
BWP24_22740	COG2182	Extracellular solute-binding protein
BWP24_22820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BWP24_22830	COG0513	Belongs to the DEAD box helicase family
BWP24_22835	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
BWP24_22850	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BWP24_22895	COG1119	ATPase activity
BWP24_22900	COG2200	EAL domain
BWP24_22920	COG0513	Belongs to the DEAD box helicase family
BWP24_22925	COG3447	MASE1 domain protein
BWP24_22925	COG5001	Diguanylate cyclase
BWP24_22925	COG5002	protein histidine kinase activity
BWP24_22960	COG3530	Putative quorum-sensing-regulated virulence factor
BWP24_22990	COG3186	Phenylalanine-4-hydroxylase
BWP24_23000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BWP24_23010	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BWP24_23030	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BWP24_23035	COG1454	alcohol dehydrogenase
BWP24_23040	COG2133	pyrroloquinoline quinone binding
BWP24_23045	COG1619	proteins homologs of microcin C7 resistance protein MccF
BWP24_23055	COG0783	Belongs to the Dps family
BWP24_23060	COG0840	transmembrane signaling receptor activity
BWP24_23070	COG1136	(ABC) transporter
BWP24_23090	COG2199	diguanylate cyclase activity
BWP24_23100	COG3036	rescue of stalled ribosome
BWP24_23105	COG1278	Cold shock
BWP24_23135	COG0545	Peptidyl-prolyl cis-trans isomerase
BWP24_23140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BWP24_23150	COG0840	transmembrane signaling receptor activity
BWP24_23175	COG2195	Cleaves the N-terminal amino acid of tripeptides
BWP24_23190	COG2197	response regulator
BWP24_23195	COG3850	Histidine kinase
BWP24_23200	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BWP24_23220	COG3005	denitrification pathway
BWP24_23240	COG0183	Belongs to the thiolase family
BWP24_23250	COG1280	lysine exporter protein (LysE YggA)
BWP24_23260	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BWP24_23265	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BWP24_23345	COG0673	inositol 2-dehydrogenase activity
BWP24_23350	COG0784	Response regulator, receiver
BWP24_23350	COG5002	protein histidine kinase activity
BWP24_23350	COG2205	protein histidine kinase activity
BWP24_23375	COG0583	DNA-binding transcription factor activity
BWP24_23390	COG0531	amino acid
BWP24_23395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWP24_23405	COG2205	protein histidine kinase activity
BWP24_23410	COG0745	RESPONSE REGULATOR receiver
BWP24_23435	COG1566	PFAM secretion protein HlyD family protein
BWP24_23440	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BWP24_23445	COG2239	Acts as a magnesium transporter
BWP24_23450	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BWP24_23455	COG0402	S-adenosylhomocysteine deaminase activity
BWP24_23470	COG1418	mRNA catabolic process
BWP24_23485	COG2814	Major facilitator Superfamily
BWP24_23495	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BWP24_23515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BWP24_23530	COG4221	oxidoreductase activity
BWP24_23540	COG0745	RESPONSE REGULATOR receiver
BWP24_23545	COG2205	protein histidine kinase activity
BWP24_23555	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BWP24_23560	COG2194	sulfuric ester hydrolase activity
BWP24_23570	COG0673	inositol 2-dehydrogenase activity
BWP24_23575	COG4977	sequence-specific DNA binding
BWP24_23610	COG0583	DNA-binding transcription factor activity
BWP24_23615	COG2249	NAD(P)H dehydrogenase (quinone) activity
BWP24_23630	COG0583	DNA-binding transcription factor activity
BWP24_23660	COG0583	DNA-binding transcription factor activity
BWP24_23670	COG0366	Alpha amylase catalytic
BWP24_23675	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BWP24_23680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BWP24_23685	COG0784	Response regulator, receiver
BWP24_23685	COG0835	chemotaxis
BWP24_23700	COG0748	coenzyme F420 binding
BWP24_23705	COG3721	Heme iron utilization protein
BWP24_23715	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BWP24_23720	COG0811	peptide transport
BWP24_23725	COG0848	biopolymer transport protein
BWP24_23735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWP24_23740	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BWP24_23780	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BWP24_23790	COG0633	Ferredoxin
BWP24_23790	COG3217	Mosc domain protein beta barrel domain protein
BWP24_23790	COG3217	Mosc domain protein beta barrel domain protein
BWP24_23790	COG0633	Ferredoxin
BWP24_23795	COG0401	homolog of Blt101
BWP24_23805	COG2354	Protein conserved in bacteria
BWP24_23840	COG1175	transmembrane transport
BWP24_23855	COG3842	ATPase activity
BWP24_23865	COG2200	EAL domain
BWP24_23870	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BWP24_23885	COG0489	protein tyrosine kinase activity
BWP24_23885	COG3206	protein involved in exopolysaccharide biosynthesis
BWP24_23930	COG1309	transcriptional regulator
BWP24_23935	COG2130	NADP-dependent
BWP24_23945	COG0753	catalase activity
BWP24_23950	COG2084	Dehydrogenase
BWP24_23960	COG0583	DNA-binding transcription factor activity
BWP24_23965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWP24_23970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWP24_23980	COG2207	Transcriptional regulator
BWP24_23985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWP24_23985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWP24_23985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWP24_24030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BWP24_24035	COG1301	dicarboxylic acid transport
BWP24_24040	COG1252	NADH dehydrogenase
BWP24_24050	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BWP24_24055	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BWP24_24090	COG2885	chlorophyll binding
BWP24_24090	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BWP24_24105	COG1028	Short-chain dehydrogenase reductase Sdr
BWP24_24110	COG4191	Histidine kinase
BWP24_24120	COG0110	maltose O-acetyltransferase activity
BWP24_24145	COG2197	response regulator
BWP24_24175	COG0714	Associated with various cellular activities
BWP24_24195	COG2304	oxidoreductase activity
BWP24_24215	COG0581	inorganic phosphate transmembrane transporter activity
BWP24_24220	COG0573	inorganic phosphate transmembrane transporter activity
BWP24_24225	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BWP24_24230	COG0840	transmembrane signaling receptor activity
BWP24_24250	COG4771	TonB-dependent receptor
BWP24_24255	COG1770	oligopeptidase
BWP24_24260	COG0513	Belongs to the DEAD box helicase family
BWP24_24270	COG1376	ErfK ybiS ycfS ynhG family protein
BWP24_24270	COG1388	LysM domain
BWP24_24275	COG0415	Belongs to the DNA photolyase family
BWP24_24280	COG0789	Transcriptional regulator
BWP24_24285	COG3272	Protein of unknown function (DUF1722)
BWP24_24290	COG0813	purine-nucleoside phosphorylase activity
BWP24_24305	COG3706	GGDEF domain
BWP24_24320	COG1566	PFAM secretion protein HlyD family protein
BWP24_24330	COG1122	ATPase activity
BWP24_24355	COG0348	domain, Protein
BWP24_24360	COG0437	4 iron, 4 sulfur cluster binding
BWP24_24365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWP24_24385	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BWP24_24395	COG1067	ATP-dependent peptidase activity
BWP24_24405	COG4172	Belongs to the ABC transporter superfamily
BWP24_24410	COG1505	serine-type exopeptidase activity
BWP24_24415	COG0583	DNA-binding transcription factor activity
BWP24_24420	COG1620	l-lactate permease
BWP24_24425	COG1304	FMN binding
BWP24_24435	COG0668	transmembrane transport
BWP24_24445	COG1063	alcohol dehydrogenase
BWP24_24450	COG2223	nitrite transmembrane transporter activity
BWP24_24455	COG2203	Gaf domain
BWP24_24455	COG2199	diguanylate cyclase activity
BWP24_24480	COG1063	alcohol dehydrogenase
BWP24_24485	COG0156	8-amino-7-oxononanoate synthase activity
BWP24_24510	COG0745	RESPONSE REGULATOR receiver
BWP24_24535	COG0346	lactoylglutathione lyase activity
BWP24_24585	COG3121	Chaperone
BWP24_24600	COG3121	Chaperone
BWP24_24625	COG2200	EAL domain
BWP24_24645	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BWP24_24660	COG2204	response regulator
BWP24_24685	COG1987	bacterial-type flagellum assembly
BWP24_24695	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BWP24_24710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWP24_24720	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BWP24_24725	COG1516	flagellar protein fliS
BWP24_24740	COG1580	Controls the rotational direction of flagella during chemotaxis
BWP24_24745	COG1191	sigma factor activity
BWP24_24750	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BWP24_24755	COG1360	Flagellar Motor Protein
BWP24_24780	COG0384	phenazine biosynthesis protein PhzF
BWP24_24845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWP24_24850	COG4786	Flagellar basal body rod
BWP24_24850	COG1256	bacterial-type flagellum assembly
BWP24_24860	COG1706	bacterial-type flagellum-dependent cell motility
BWP24_24865	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BWP24_24870	COG4786	Flagellar basal body rod
BWP24_24875	COG4787	bacterial-type flagellum-dependent cell motility
BWP24_24880	COG1749	Flagellar hook protein flgE
BWP24_24885	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BWP24_24890	COG1558	bacterial-type flagellum-dependent cell motility
BWP24_24895	COG1815	bacterial-type flagellum-dependent cell motility
BWP24_24915	COG0741	lytic transglycosylase activity
BWP24_24915	COG1388	LysM domain
BWP24_24940	COG1760	l-serine dehydratase
BWP24_24970	COG0583	DNA-binding transcription factor activity
BWP24_24980	COG2866	Carboxypeptidase
BWP24_24985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BWP24_24995	COG2990	Protein conserved in bacteria
BWP24_25020	COG3842	ATPase activity
BWP24_25025	COG1840	ABC-type Fe3 transport system, periplasmic component
BWP24_25055	COG3240	lipase activity
BWP24_25080	COG1011	Hydrolase
BWP24_25115	COG1765	OsmC-like protein
BWP24_25120	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWP24_25120	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWP24_25135	COG3046	protein related to deoxyribodipyrimidine photolyase
BWP24_25140	COG0415	Belongs to the DNA photolyase family
BWP24_25145	COG3706	GGDEF domain
BWP24_25180	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BWP24_25185	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BWP24_25205	COG3033	Beta-eliminating lyase
BWP24_25225	COG0579	oxidoreductase
BWP24_25240	COG1114	Component of the transport system for branched-chain amino acids
BWP24_25285	COG0583	DNA-binding transcription factor activity
BWP24_25295	COG0189	ligase activity
BWP24_25300	COG0189	ligase activity
BWP24_25300	COG4067	protein conserved in archaea
BWP24_25310	COG1166	arginine decarboxylase activity
BWP24_25315	COG0010	Belongs to the arginase family
BWP24_25320	COG2814	Major facilitator Superfamily
BWP24_25325	COG1770	oligopeptidase
BWP24_25340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BWP24_25345	COG1121	(ABC) transporter
BWP24_25350	COG0803	Belongs to the bacterial solute-binding protein 9 family
BWP24_25395	COG0848	biopolymer transport protein
BWP24_25400	COG0811	peptide transport
BWP24_25405	COG0811	peptide transport
BWP24_25425	COG0745	RESPONSE REGULATOR receiver
BWP24_25430	COG0584	glycerophosphoryl diester phosphodiesterase
BWP24_25440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BWP24_25505	COG0312	modulator of DNA gyrase
BWP24_25510	COG0312	modulator of DNA gyrase
BWP24_25515	COG0351	phosphomethylpyrimidine kinase
BWP24_25520	COG1116	anion transmembrane transporter activity
BWP24_25525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BWP24_25530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BWP24_25535	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BWP24_25550	COG0671	phosphoesterase, PA-phosphatase related
BWP24_25555	COG0243	molybdopterin cofactor binding
BWP24_25560	COG3005	denitrification pathway
BWP24_25570	COG1028	Short-chain dehydrogenase reductase Sdr
BWP24_25590	COG0456	acetyltransferase
BWP24_25630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWP24_25635	COG1929	Belongs to the glycerate kinase type-1 family
BWP24_25640	COG3835	regulator
BWP24_25725	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BWP24_25725	COG3408	Glycogen debranching enzyme
BWP24_25745	COG2814	Major facilitator Superfamily
BWP24_25755	COG3047	cAMP biosynthetic process
BWP24_25760	COG1357	PFAM Pentapeptide repeats (8 copies)
BWP24_25775	COG0534	Mate efflux family protein
BWP24_25790	COG2076	Multidrug Resistance protein
BWP24_25840	COG0583	DNA-binding transcription factor activity
BWP24_25860	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BWP24_25875	COG3152	Membrane
BWP24_25895	COG0561	phosphatase activity
BWP24_25900	COG0564	pseudouridine synthase activity
BWP24_25905	COG0534	Mate efflux family protein
BWP24_25910	COG1472	Belongs to the glycosyl hydrolase 3 family
BWP24_25935	COG1609	Transcriptional regulator
BWP24_25945	COG4608	Belongs to the ABC transporter superfamily
BWP24_25950	COG0444	Belongs to the ABC transporter superfamily
BWP24_25955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWP24_25965	COG0747	negative chemotaxis
BWP24_25975	COG1609	Transcriptional regulator
BWP24_25980	COG3842	ATPase activity
BWP24_25985	COG2723	6-phospho-beta-galactosidase activity
BWP24_25990	COG0395	ABC-type sugar transport system, permease component
BWP24_26005	COG1609	Transcriptional regulator
BWP24_26015	COG5001	Diguanylate cyclase
BWP24_26065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BWP24_26075	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BWP24_26080	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BWP24_26090	COG2259	Doxx family
BWP24_26140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BWP24_26145	COG0251	oxidation-reduction process
BWP24_26160	COG0659	secondary active sulfate transmembrane transporter activity
BWP24_26170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWP24_26180	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BWP24_26185	COG2207	Transcriptional regulator
BWP24_26195	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BWP24_26230	COG1609	Transcriptional regulator
BWP24_26230	COG2207	Transcriptional regulator
BWP24_26240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BWP24_26265	COG0786	glutamate:sodium symporter activity
BWP24_26270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWP24_26275	COG1131	(ABC) transporter
BWP24_26310	COG1028	Short-chain dehydrogenase reductase Sdr
BWP24_26315	COG0786	glutamate:sodium symporter activity
BWP24_26335	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BWP24_26345	COG3279	Response regulator of the LytR AlgR family
BWP24_26350	COG3275	phosphorelay sensor kinase activity
BWP24_26370	COG1136	(ABC) transporter
BWP24_26380	COG0583	DNA-binding transcription factor activity
BWP24_26385	COG1566	PFAM secretion protein HlyD family protein
BWP24_26395	COG0772	Belongs to the SEDS family
BWP24_26420	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BWP24_26420	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
BWP24_26450	COG0517	IMP dehydrogenase activity
BWP24_26455	COG4974	Belongs to the 'phage' integrase family
BWP24_26630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BWP24_26680	COG1192	Involved in chromosome partitioning
BWP24_27215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BWP24_27310	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BWP24_27360	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BWP24_27505	COG3015	lipoprotein NlpE involved in copper resistance
BWP24_27630	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BWP24_27690	COG2261	transglycosylase associated protein
BWP24_27805	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BWP24_27845	COG3451	type IV secretory pathway VirB4
BWP24_27865	COG3736	Type IV secretory pathway, component VirB8
BWP24_27870	COG3504	Conjugal transfer protein
BWP24_27935	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BWP24_28185	COG0484	heat shock protein binding
BWP24_28230	COG2314	TM2 domain
BWP24_28290	COG1192	Involved in chromosome partitioning
BWP24_28335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BWP24_28390	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BWP24_28395	COG0629	single-stranded DNA binding
BWP24_28425	COG3451	type IV secretory pathway VirB4
BWP24_28440	COG3736	Type IV secretory pathway, component VirB8
BWP24_28450	COG2948	multi-organism process
BWP24_28485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BWP24_28620	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BWP24_28720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BWP24_28830	COG4974	Belongs to the 'phage' integrase family
BWP24_28950	COG1192	Involved in chromosome partitioning
BWP24_28955	COG1475	DNA binding