locus-tag	class	description
VCA1552_00001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VCA1552_00002	COG0592	DNA-directed DNA polymerase activity
VCA1552_00003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VCA1552_00004	COG0187	DNA topoisomerase II activity
VCA1552_00007	COG0071	Belongs to the small heat shock protein (HSP20) family
VCA1552_00008	COG3977	Valine--pyruvate aminotransferase
VCA1552_00009	COG0751	glycine-tRNA ligase activity
VCA1552_00010	COG0752	glycyl-tRNA synthetase alpha subunit
VCA1552_00012	COG2119	membrane
VCA1552_00014	COG0425	Belongs to the sulfur carrier protein TusA family
VCA1552_00016	COG0604	alcohol dehydrogenase
VCA1552_00018	COG0129	dihydroxy-acid dehydratase activity
VCA1552_00019	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCA1552_00022	COG0606	chelatase, subunit chli
VCA1552_00023	COG0204	Acyl-transferase
VCA1552_00024	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCA1552_00025	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VCA1552_00027	COG3084	Protein conserved in bacteria
VCA1552_00028	COG4326	sporulation control protein
VCA1552_00029	COG1272	protein, Hemolysin III
VCA1552_00031	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCA1552_00032	COG0569	domain protein
VCA1552_00033	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCA1552_00033	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VCA1552_00034	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VCA1552_00035	COG0242	peptide deformylase activity
VCA1552_00036	COG1652	LysM domain
VCA1552_00037	COG0758	DNA mediated transformation
VCA1552_00038	COG2922	Belongs to the Smg family
VCA1552_00039	COG0551	DNA topoisomerase type I activity
VCA1552_00040	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VCA1552_00041	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VCA1552_00042	COG0009	L-threonylcarbamoyladenylate synthase
VCA1552_00043	COG0408	coproporphyrinogen oxidase activity
VCA1552_00044	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VCA1552_00046	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VCA1552_00052	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VCA1552_00054	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VCA1552_00056	COG1072	(Pantothenic acid kinase))
VCA1552_00061	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCA1552_00062	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCA1552_00063	COG0250	Participates in transcription elongation, termination and antitermination
VCA1552_00064	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VCA1552_00065	COG0081	regulation of translation
VCA1552_00066	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VCA1552_00067	COG0222	ribosome binding
VCA1552_00068	COG0085	RNA polymerase activity
VCA1552_00069	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VCA1552_00070	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VCA1552_00071	COG2816	NAD+ diphosphatase activity
VCA1552_00072	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VCA1552_00075	COG4942	peptidase
VCA1552_00076	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VCA1552_00078	COG0471	metal ion transport
VCA1552_00079	COG0688	phosphatidylethanolamine metabolic process
VCA1552_00080	COG1162	GTPase activity
VCA1552_00081	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VCA1552_00092	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VCA1552_00093	COG0802	atpase or kinase
VCA1552_00095	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VCA1552_00096	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VCA1552_00097	COG1923	regulation of RNA biosynthetic process
VCA1552_00098	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VCA1552_00099	COG0330	HflC and HflK could
VCA1552_00100	COG0330	HflC and HflK could
VCA1552_00101	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VCA1552_00102	COG2900	Belongs to the SlyX family
VCA1552_00104	COG0545	Peptidyl-prolyl cis-trans isomerase
VCA1552_00105	COG2964	Protein conserved in bacteria
VCA1552_00106	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VCA1552_00107	COG2923	Belongs to the DsrF TusC family
VCA1552_00109	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
VCA1552_00110	COG0049	tRNA binding
VCA1552_00111	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCA1552_00112	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCA1552_00113	COG2906	2 iron, 2 sulfur cluster binding
VCA1552_00115	COG0360	Binds together with S18 to 16S ribosomal RNA
VCA1552_00116	COG2965	DNA replication, synthesis of RNA primer
VCA1552_00117	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
VCA1552_00118	COG0359	binds to the 23S rRNA
VCA1552_00120	COG0305	Participates in initiation and elongation during chromosome replication
VCA1552_00121	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCA1552_00122	COG0432	Pfam Uncharacterised protein family UPF0047
VCA1552_00123	COG0166	Belongs to the GPI family
VCA1552_00126	COG0735	belongs to the Fur family
VCA1552_00127	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCA1552_00131	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCA1552_00132	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VCA1552_00133	COG0175	sulfate reduction
VCA1552_00147	COG1410	methionine synthase
VCA1552_00147	COG0646	methionine synthase
VCA1552_00148	COG0527	aspartate kinase activity
VCA1552_00150	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCA1552_00152	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VCA1552_00155	COG0629	single-stranded DNA binding
VCA1552_00156	COG2199	diguanylate cyclase activity
VCA1552_00156	COG2200	EAL domain
VCA1552_00161	COG3409	Peptidoglycan-binding domain 1 protein
VCA1552_00161	COG3267	Type II secretory pathway component ExeA
VCA1552_00163	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCA1552_00164	COG1459	type II secretion system
VCA1552_00173	COG1077	Cell shape determining protein MreB Mrl
VCA1552_00174	COG1792	Involved in formation and maintenance of cell shape
VCA1552_00175	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VCA1552_00176	COG0424	maF-like protein
VCA1552_00177	COG1530	ribonuclease E activity
VCA1552_00178	COG3164	Protein of unknown function
VCA1552_00179	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VCA1552_00180	COG0312	modulator of DNA gyrase
VCA1552_00181	COG2235	arginine
VCA1552_00185	COG0589	response to stress
VCA1552_00188	COG1438	arginine binding
VCA1552_00189	COG0039	L-malate dehydrogenase activity
VCA1552_00190	COG0531	amino acid
VCA1552_00191	COG0142	geranyltranstransferase activity
VCA1552_00192	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VCA1552_00193	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VCA1552_00194	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VCA1552_00195	COG2966	Psort location CytoplasmicMembrane, score
VCA1552_00196	COG3610	response to peptide
VCA1552_00198	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VCA1552_00199	COG2967	ApaG domain
VCA1552_00200	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VCA1552_00201	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VCA1552_00202	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCA1552_00203	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VCA1552_00204	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VCA1552_00215	COG0741	lytic transglycosylase activity
VCA1552_00216	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VCA1552_00217	COG1194	a g-specific adenine glycosylase
VCA1552_00218	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VCA1552_00219	COG2066	Belongs to the glutaminase family
VCA1552_00220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VCA1552_00221	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VCA1552_00223	COG1872	DUF167
VCA1552_00224	COG0762	integral membrane protein
VCA1552_00225	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VCA1552_00226	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VCA1552_00230	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCA1552_00231	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VCA1552_00232	COG1678	Uncharacterized ACR, COG1678
VCA1552_00233	COG0189	ligase activity
VCA1552_00234	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VCA1552_00235	COG2356	endonuclease I
VCA1552_00236	COG3091	SprT-like family
VCA1552_00237	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VCA1552_00238	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCA1552_00239	COG0583	DNA-binding transcription factor activity
VCA1552_00240	COG4771	TonB-dependent receptor
VCA1552_00241	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCA1552_00242	COG0126	phosphoglycerate kinase activity
VCA1552_00243	COG0191	fructose-bisphosphate aldolase activity
VCA1552_00244	COG0668	transmembrane transport
VCA1552_00245	COG1279	arginine transmembrane transporter activity
VCA1552_00246	COG0583	DNA-binding transcription factor activity
VCA1552_00249	COG0469	pyruvate kinase activity
VCA1552_00250	COG1349	DNA-binding transcription factor activity
VCA1552_00251	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VCA1552_00252	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCA1552_00263	COG0328	RNA-DNA hybrid ribonuclease activity
VCA1552_00268	COG0739	heme binding
VCA1552_00274	COG2003	Belongs to the UPF0758 family
VCA1552_00280	COG0582	viral genome integration into host DNA
VCA1552_00282	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCA1552_00283	COG0358	DNA primase activity
VCA1552_00284	COG1610	YqeY-like protein
VCA1552_00285	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VCA1552_00286	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VCA1552_00288	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VCA1552_00289	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VCA1552_00290	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCA1552_00291	COG1968	undecaprenyl-diphosphatase activity
VCA1552_00292	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VCA1552_00293	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VCA1552_00294	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VCA1552_00295	COG0585	pseudouridine synthase activity
VCA1552_00296	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VCA1552_00297	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VCA1552_00298	COG4942	peptidase
VCA1552_00298	COG1388	LysM domain
VCA1552_00299	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCA1552_00300	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VCA1552_00304	COG4208	sulfate ABC transporter
VCA1552_00305	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
VCA1552_00307	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VCA1552_00308	COG2137	regulation of response to DNA damage stimulus
VCA1552_00309	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VCA1552_00310	COG0527	aspartate kinase activity
VCA1552_00311	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
VCA1552_00320	COG3630	sodium ion export across plasma membrane
VCA1552_00321	COG5016	pyruvate
VCA1552_00321	COG0511	ligase activity, forming carbon-carbon bonds
VCA1552_00322	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCA1552_00324	COG1238	metal cluster binding
VCA1552_00325	COG0612	Peptidase, M16
VCA1552_00326	COG2918	glutathione biosynthetic process
VCA1552_00327	COG1854	S-ribosylhomocysteine lyase activity
VCA1552_00328	COG4536	flavin adenine dinucleotide binding
VCA1552_00329	COG4137	Cytochrome C assembly protein
VCA1552_00330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VCA1552_00331	COG0228	four-way junction DNA binding
VCA1552_00332	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VCA1552_00333	COG0336	Belongs to the RNA methyltransferase TrmD family
VCA1552_00334	COG0335	large ribosomal subunit rRNA binding
VCA1552_00335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCA1552_00336	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCA1552_00338	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VCA1552_00339	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VCA1552_00340	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VCA1552_00341	COG0723	plastoquinol--plastocyanin reductase activity
VCA1552_00342	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VCA1552_00343	COG2857	Cytochrome c1
VCA1552_00344	COG0625	glutathione transferase activity
VCA1552_00345	COG2969	positive regulation of protein catabolic process
VCA1552_00346	COG2823	Periplasmic or secreted lipoprotein
VCA1552_00347	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCA1552_00348	COG0792	nuclease activity
VCA1552_00349	COG3107	peptidoglycan biosynthetic process
VCA1552_00350	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VCA1552_00353	COG0288	reversible hydration of carbon dioxide
VCA1552_00354	COG0659	secondary active sulfate transmembrane transporter activity
VCA1552_00355	COG1131	(ABC) transporter
VCA1552_00356	COG0842	Transport permease protein
VCA1552_00357	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VCA1552_00358	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VCA1552_00359	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCA1552_00361	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCA1552_00362	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VCA1552_00363	COG1489	DNA binding
VCA1552_00365	COG1643	Atp-dependent helicase
VCA1552_00366	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VCA1552_00367	COG1752	Esterase of the alpha-beta hydrolase superfamily
VCA1552_00368	COG1049	propionate catabolic process, 2-methylcitrate cycle
VCA1552_00369	COG3112	Uncharacterised protein family (UPF0231)
VCA1552_00370	COG0347	Belongs to the P(II) protein family
VCA1552_00371	COG0004	ammonium transporteR
VCA1552_00372	COG1840	ABC-type Fe3 transport system, periplasmic component
VCA1552_00374	COG3842	ATPase activity
VCA1552_00378	COG2971	BadF BadG BcrA BcrD
VCA1552_00380	COG4608	Belongs to the ABC transporter superfamily
VCA1552_00381	COG0444	Belongs to the ABC transporter superfamily
VCA1552_00382	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCA1552_00383	COG0601	transmembrane transport
VCA1552_00384	COG0747	negative chemotaxis
VCA1552_00386	COG2813	Specifically methylates the guanine in position
VCA1552_00387	COG0628	permease
VCA1552_00389	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VCA1552_00390	COG0316	Belongs to the HesB IscA family
VCA1552_00393	COG0739	heme binding
VCA1552_00394	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCA1552_00395	COG2027	D-alanyl-D-alanine carboxypeptidase
VCA1552_00396	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCA1552_00397	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCA1552_00398	COG1534	Rna-binding protein
VCA1552_00399	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VCA1552_00400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VCA1552_00401	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VCA1552_00402	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCA1552_00404	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCA1552_00408	COG0779	Required for maturation of 30S ribosomal subunits
VCA1552_00409	COG0195	Participates in both transcription termination and antitermination
VCA1552_00410	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VCA1552_00411	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VCA1552_00412	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
VCA1552_00414	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VCA1552_00415	COG1185	polyribonucleotide nucleotidyltransferase activity
VCA1552_00416	COG4785	May be involved in cell division
VCA1552_00423	COG3153	acetyltransferase
VCA1552_00427	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
VCA1552_00428	COG0513	Belongs to the DEAD box helicase family
VCA1552_00429	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
VCA1552_00431	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VCA1552_00432	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VCA1552_00433	COG2204	response regulator
VCA1552_00435	COG0667	Aldo Keto reductase
VCA1552_00436	COG3066	DNA modification
VCA1552_00437	COG0494	nUDIX hydrolase
VCA1552_00438	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
VCA1552_00439	COG0730	response to heat
VCA1552_00440	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VCA1552_00441	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
VCA1552_00442	COG1283	sodium-dependent phosphate transmembrane transporter activity
VCA1552_00443	COG0583	DNA-binding transcription factor activity
VCA1552_00444	COG0640	Transcriptional regulator
VCA1552_00445	COG0268	Binds directly to 16S ribosomal RNA
VCA1552_00446	COG0728	peptidoglycan biosynthetic process
VCA1552_00447	COG0196	riboflavin kinase activity
VCA1552_00448	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
VCA1552_00449	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VCA1552_00450	COG1047	Peptidyl-prolyl cis-trans
VCA1552_00451	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VCA1552_00452	COG1966	Carbon starvation protein
VCA1552_00455	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCA1552_00456	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VCA1552_00457	COG1472	Belongs to the glycosyl hydrolase 3 family
VCA1552_00458	COG3279	Response regulator of the LytR AlgR family
VCA1552_00459	COG3275	phosphorelay sensor kinase activity
VCA1552_00460	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCA1552_00461	COG0287	Prephenate dehydrogenase
VCA1552_00461	COG1605	Chorismate mutase
VCA1552_00463	COG0488	(ABC) transporter
VCA1552_00465	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VCA1552_00466	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
VCA1552_00467	COG5001	Diguanylate cyclase
VCA1552_00468	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCA1552_00469	COG0077	Prephenate dehydratase
VCA1552_00469	COG1605	Chorismate mutase
VCA1552_00471	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCA1552_00472	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCA1552_00473	COG0564	pseudouridine synthase activity
VCA1552_00475	COG0542	response to heat
VCA1552_00483	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCA1552_00485	COG2974	May be involved in recombination
VCA1552_00486	COG0745	RESPONSE REGULATOR receiver
VCA1552_00487	COG5002	protein histidine kinase activity
VCA1552_00489	COG0248	Ppx GppA phosphatase
VCA1552_00490	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VCA1552_00492	COG0581	inorganic phosphate transmembrane transporter activity
VCA1552_00493	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCA1552_00496	COG3142	Participates in the control of copper homeostasis
VCA1552_00497	COG0450	alkyl hydroperoxide reductase
VCA1552_00498	COG0583	DNA-binding transcription factor activity
VCA1552_00499	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VCA1552_00501	COG0517	IMP dehydrogenase activity
VCA1552_00502	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
VCA1552_00503	COG0343	queuine tRNA-ribosyltransferase activity
VCA1552_00504	COG1862	Preprotein translocase
VCA1552_00505	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCA1552_00506	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCA1552_00507	COG0483	inositol monophosphate 1-phosphatase activity
VCA1552_00509	COG1959	2 iron, 2 sulfur cluster binding
VCA1552_00510	COG1104	cysteine desulfurase activity
VCA1552_00511	COG0822	iron-sulfur transferase activity
VCA1552_00513	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VCA1552_00514	COG0443	Heat shock 70 kDa protein
VCA1552_00515	COG0633	Ferredoxin
VCA1552_00516	COG2975	iron-sulfur cluster assembly
VCA1552_00517	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCA1552_00518	COG0105	UTP biosynthetic process
VCA1552_00519	COG0820	rRNA (adenine-C2-)-methyltransferase activity
VCA1552_00521	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VCA1552_00522	COG0124	histidyl-tRNA synthetase
VCA1552_00523	COG2976	Protein conserved in bacteria
VCA1552_00524	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCA1552_00525	COG1160	GTP binding
VCA1552_00528	COG1570	exodeoxyribonuclease VII activity
VCA1552_00529	COG0517	IMP dehydrogenase activity
VCA1552_00529	COG0516	GMP reductase activity
VCA1552_00530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VCA1552_00530	COG0519	Catalyzes the synthesis of GMP from XMP
VCA1552_00532	COG1584	GPR1 FUN34 yaaH family protein
VCA1552_00533	COG3433	isochorismatase activity
VCA1552_00533	COG1535	isochorismatase
VCA1552_00534	COG1021	2,3-dihydroxybenzoate-AMP ligase
VCA1552_00535	COG1169	isochorismate synthase
VCA1552_00536	COG1028	Short-chain dehydrogenase reductase Sdr
VCA1552_00538	COG4592	Periplasmic binding protein
VCA1552_00539	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCA1552_00540	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCA1552_00541	COG1120	ATPase activity
VCA1552_00543	COG0583	DNA-binding transcription factor activity
VCA1552_00544	COG2015	COG2015, Alkyl sulfatase and related hydrolases
VCA1552_00545	COG1115	amino acid carrier protein
VCA1552_00546	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VCA1552_00547	COG0583	DNA-binding transcription factor activity
VCA1552_00550	COG4565	transcriptional regulatory protein
VCA1552_00552	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCA1552_00553	COG0511	ligase activity, forming carbon-carbon bonds
VCA1552_00553	COG5016	pyruvate
VCA1552_00554	COG3630	sodium ion export across plasma membrane
VCA1552_00556	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
VCA1552_00557	COG3052	prosthetic group binding
VCA1552_00558	COG2301	Belongs to the HpcH HpaI aldolase family
VCA1552_00559	COG3051	citrate lyase alpha subunit
VCA1552_00560	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
VCA1552_00561	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
VCA1552_00563	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCA1552_00564	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VCA1552_00565	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VCA1552_00576	COG1012	belongs to the aldehyde dehydrogenase family
VCA1552_00580	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
VCA1552_00581	COG0840	transmembrane signaling receptor activity
VCA1552_00582	COG3710	Transcriptional regulator
VCA1552_00584	COG2165	general secretion pathway protein
VCA1552_00587	COG4796	Type ii and iii secretion system protein
VCA1552_00591	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCA1552_00592	COG1459	type II secretion system
VCA1552_00594	COG2207	Transcriptional regulator
VCA1552_00595	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
VCA1552_00600	COG0739	heme binding
VCA1552_00602	COG3064	Membrane
VCA1552_00603	COG0582	viral genome integration into host DNA
VCA1552_00605	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VCA1552_00606	COG2867	negative regulation of translational initiation
VCA1552_00607	COG2914	Belongs to the UPF0125 (RnfH) family
VCA1552_00608	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCA1552_00609	COG0497	DNA recombination
VCA1552_00610	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VCA1552_00611	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VCA1552_00612	COG0443	Heat shock 70 kDa protein
VCA1552_00613	COG0484	heat shock protein binding
VCA1552_00619	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCA1552_00620	COG0590	tRNA wobble adenosine to inosine editing
VCA1552_00622	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VCA1552_00623	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VCA1552_00623	COG0047	phosphoribosylformylglycinamidine synthase activity
VCA1552_00624	COG1943	Transposase
VCA1552_00628	COG0442	prolyl-tRNA aminoacylation
VCA1552_00629	COG1720	tRNA m6t6A37 methyltransferase activity
VCA1552_00630	COG0254	rRNA binding
VCA1552_00631	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCA1552_00632	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCA1552_00633	COG1671	Belongs to the UPF0178 family
VCA1552_00636	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCA1552_00639	COG3098	single-species biofilm formation
VCA1552_00640	COG0564	pseudouridine synthase activity
VCA1552_00641	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VCA1552_00642	COG0142	geranyltranstransferase activity
VCA1552_00643	COG1722	exodeoxyribonuclease VII activity
VCA1552_00644	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VCA1552_00646	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCA1552_00646	COG0301	tRNA thio-modification
VCA1552_00648	COG0583	DNA-binding transcription factor activity
VCA1552_00649	COG2363	Small membrane protein
VCA1552_00650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCA1552_00651	COG1611	Belongs to the LOG family
VCA1552_00652	COG3706	GGDEF domain
VCA1552_00654	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCA1552_00654	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCA1552_00656	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VCA1552_00657	COG1464	Belongs to the NlpA lipoprotein family
VCA1552_00658	COG2011	ABC-type metal ion transport system permease component
VCA1552_00659	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VCA1552_00660	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCA1552_00661	COG1609	Transcriptional regulator
VCA1552_00662	COG1263	PTS System
VCA1552_00662	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCA1552_00663	COG0366	Alpha amylase catalytic
VCA1552_00669	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCA1552_00672	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VCA1552_00673	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VCA1552_00674	COG0110	maltose O-acetyltransferase activity
VCA1552_00678	COG1045	serine acetyltransferase
VCA1552_00680	COG0438	transferase activity, transferring glycosyl groups
VCA1552_00682	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
VCA1552_00688	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCA1552_00690	COG1596	polysaccharide export
VCA1552_00695	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCA1552_00697	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VCA1552_00698	COG0321	lipoyl(octanoyl) transferase activity
VCA1552_00699	COG2921	Belongs to the UPF0250 family
VCA1552_00700	COG1686	Belongs to the peptidase S11 family
VCA1552_00701	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCA1552_00702	COG0772	Belongs to the SEDS family
VCA1552_00703	COG0768	penicillin binding
VCA1552_00704	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VCA1552_00705	COG0799	negative regulation of ribosome biogenesis
VCA1552_00706	COG1466	dna polymerase III delta subunit
VCA1552_00707	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VCA1552_00708	COG0495	leucyl-tRNA aminoacylation
VCA1552_00709	COG2888	peptidyl-tyrosine sulfation
VCA1552_00710	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VCA1552_00711	COG4535	Mg2 and Co2 transporter CorC
VCA1552_00712	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VCA1552_00713	COG1702	phosphate starvation-inducible protein PhoH
VCA1552_00714	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCA1552_00715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCA1552_00716	COG2190	(PTS) system
VCA1552_00718	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCA1552_00719	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VCA1552_00720	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VCA1552_00721	COG3115	cell septum assembly
VCA1552_00722	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VCA1552_00725	COG0789	Transcriptional regulator
VCA1552_00726	COG1585	Membrane protein implicated in regulation of membrane protease activity
VCA1552_00727	COG0330	HflC and HflK could
VCA1552_00728	COG3118	belongs to the thioredoxin family
VCA1552_00729	COG0300	oxidoreductase activity
VCA1552_00730	COG1090	epimerase
VCA1552_00731	COG0622	Phosphoesterase
VCA1552_00734	COG3710	Transcriptional regulator
VCA1552_00735	COG0326	Molecular chaperone. Has ATPase activity
VCA1552_00736	COG0563	adenylate kinase activity
VCA1552_00737	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VCA1552_00740	COG0367	asparagine synthase
VCA1552_00741	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCA1552_00741	COG4651	solute:proton antiporter activity
VCA1552_00742	COG1940	carbohydrate kinase activity
VCA1552_00742	COG1846	Transcriptional regulator
VCA1552_00743	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VCA1552_00744	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCA1552_00744	COG1263	PTS System
VCA1552_00744	COG2190	(PTS) system
VCA1552_00745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCA1552_00747	COG0101	tRNA pseudouridine synthase activity
VCA1552_00748	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VCA1552_00749	COG0285	dihydrofolate synthase activity
VCA1552_00750	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VCA1552_00751	COG1286	toxin biosynthetic process
VCA1552_00752	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VCA1552_00753	COG2056	Na+-H+ antiporter family
VCA1552_00754	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VCA1552_00757	COG0346	lactoylglutathione lyase activity
VCA1552_00758	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VCA1552_00759	COG4660	Part of a membrane complex involved in electron transport
VCA1552_00760	COG4659	FMN binding
VCA1552_00761	COG4658	electron transport chain
VCA1552_00762	COG4656	Part of a membrane complex involved in electron transport
VCA1552_00763	COG2878	Part of a membrane complex involved in electron transport
VCA1552_00764	COG4657	Part of a membrane complex involved in electron transport
VCA1552_00766	COG0556	nucleotide-excision repair
VCA1552_00768	COG2204	response regulator
VCA1552_00769	COG2198	Histidine kinase
VCA1552_00770	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VCA1552_00772	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VCA1552_00773	COG0521	Mo-molybdopterin cofactor biosynthetic process
VCA1552_00774	COG0315	cyclic pyranopterin monophosphate synthase activity
VCA1552_00775	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VCA1552_00776	COG0314	molybdopterin synthase activity
VCA1552_00777	COG2199	diguanylate cyclase activity
VCA1552_00778	COG4109	DRTGG domain
VCA1552_00780	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCA1552_00782	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCA1552_00782	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCA1552_00783	COG0489	protein tyrosine kinase activity
VCA1552_00784	COG0572	uridine kinase
VCA1552_00785	COG2982	Protein involved in outer membrane biogenesis
VCA1552_00786	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VCA1552_00787	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VCA1552_00793	COG0183	Belongs to the thiolase family
VCA1552_00794	COG1024	Enoyl-CoA hydratase
VCA1552_00794	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCA1552_00795	COG0778	Nitroreductase
VCA1552_00796	COG0583	DNA-binding transcription factor activity
VCA1552_00797	COG0745	RESPONSE REGULATOR receiver
VCA1552_00799	COG2832	Protein of unknown function (DUF454)
VCA1552_00800	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VCA1552_00802	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VCA1552_00803	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VCA1552_00806	COG1028	Short-chain dehydrogenase reductase Sdr
VCA1552_00807	COG0616	signal peptide processing
VCA1552_00809	COG1522	sequence-specific DNA binding
VCA1552_00810	COG1946	Acyl-CoA thioesterase
VCA1552_00814	COG3706	GGDEF domain
VCA1552_00817	COG0640	Transcriptional regulator
VCA1552_00818	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCA1552_00823	COG1881	PFAM PEBP family protein
VCA1552_00826	COG0009	L-threonylcarbamoyladenylate synthase
VCA1552_00829	COG2201	protein-glutamate methylesterase activity
VCA1552_00831	COG5002	protein histidine kinase activity
VCA1552_00832	COG4191	Histidine kinase
VCA1552_00833	COG3300	MHYT domain
VCA1552_00833	COG5001	Diguanylate cyclase
VCA1552_00834	COG2204	response regulator
VCA1552_00838	COG0601	transmembrane transport
VCA1552_00839	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCA1552_00840	COG0444	Belongs to the ABC transporter superfamily
VCA1552_00841	COG4608	Belongs to the ABC transporter superfamily
VCA1552_00842	COG0435	Glutathione S-transferase
VCA1552_00843	COG0857	belongs to the CobB CobQ family
VCA1552_00843	COG0280	phosphate acetyltransferase
VCA1552_00844	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCA1552_00845	COG3092	negative regulation of chromosome organization
VCA1552_00846	COG4628	conserved protein (DUF2132)
VCA1552_00848	COG4120	Belongs to the binding-protein-dependent transport system permease family
VCA1552_00850	COG2199	diguanylate cyclase activity
VCA1552_00850	COG2203	Gaf domain
VCA1552_00851	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCA1552_00853	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VCA1552_00854	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VCA1552_00855	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VCA1552_00856	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VCA1552_00857	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCA1552_00858	COG0156	8-amino-7-oxononanoate synthase activity
VCA1552_00859	COG2226	methyltransferase
VCA1552_00860	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VCA1552_00862	COG0501	Belongs to the peptidase M48B family
VCA1552_00864	COG0300	oxidoreductase activity
VCA1552_00867	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VCA1552_00869	COG2268	Band 7 protein
VCA1552_00871	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VCA1552_00872	COG2915	High frequency lysogenization protein hflD homolog
VCA1552_00873	COG0482	sulfurtransferase activity
VCA1552_00874	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCA1552_00875	COG2916	Histone family protein nucleoid-structuring protein H-NS
VCA1552_00877	COG1757	Na H antiporter
VCA1552_00879	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VCA1552_00880	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VCA1552_00881	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VCA1552_00882	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCA1552_00882	COG0131	Imidazoleglycerol-phosphate dehydratase
VCA1552_00883	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VCA1552_00884	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VCA1552_00885	COG0107	imidazoleglycerol-phosphate synthase activity
VCA1552_00886	COG0140	phosphoribosyl-ATP diphosphatase activity
VCA1552_00886	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VCA1552_00887	COG1187	pseudouridine synthase activity
VCA1552_00889	COG1278	Cold shock
VCA1552_00890	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VCA1552_00891	COG0542	response to heat
VCA1552_00893	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCA1552_00894	COG1454	alcohol dehydrogenase
VCA1552_00894	COG1012	belongs to the aldehyde dehydrogenase family
VCA1552_00895	COG1737	Transcriptional regulator
VCA1552_00896	COG0076	glutamate decarboxylase activity
VCA1552_00898	COG2431	L-lysine efflux transmembrane transporter activity
VCA1552_00900	COG3070	regulator of competence-specific genes
VCA1552_00903	COG3852	Histidine kinase
VCA1552_00905	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VCA1552_00908	COG4067	protein conserved in archaea
VCA1552_00908	COG0189	ligase activity
VCA1552_00909	COG0500	methyltransferase
VCA1552_00910	COG4106	trans-aconitate 2-methyltransferase activity
VCA1552_00911	COG1801	Protein of unknown function DUF72
VCA1552_00912	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VCA1552_00913	COG1435	thymidine kinase activity
VCA1552_00915	COG0159	tryptophan synthase activity
VCA1552_00916	COG0133	tryptophan synthase activity
VCA1552_00917	COG0134	indole-3-glycerol-phosphate synthase activity
VCA1552_00917	COG0135	phosphoribosylanthranilate isomerase activity
VCA1552_00918	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VCA1552_00919	COG0512	Glutamine amidotransferase of anthranilate synthase
VCA1552_00920	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCA1552_00922	COG0613	PHP domain protein
VCA1552_00923	COG0009	L-threonylcarbamoyladenylate synthase
VCA1552_00924	COG1187	pseudouridine synthase activity
VCA1552_00925	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VCA1552_00926	COG4988	ABC transporter
VCA1552_00927	COG0492	ferredoxin-NADP+ reductase activity
VCA1552_00929	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCA1552_00930	COG3706	GGDEF domain
VCA1552_00931	COG2949	membrane
VCA1552_00933	COG0281	malic enzyme
VCA1552_00935	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VCA1552_00939	COG2885	chlorophyll binding
VCA1552_00942	COG0247	lactate metabolic process
VCA1552_00942	COG0277	FAD linked oxidase domain protein
VCA1552_00946	COG2986	histidine ammonia-lyase
VCA1552_00947	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VCA1552_00948	COG0010	Belongs to the arginase family
VCA1552_00949	COG1228	amidohydrolase
VCA1552_00953	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCA1552_00955	COG5001	Diguanylate cyclase
VCA1552_00956	COG0417	DNA replication proofreading
VCA1552_00957	COG2197	response regulator
VCA1552_00958	COG0322	excinuclease ABC activity
VCA1552_00964	COG3706	GGDEF domain
VCA1552_00964	COG0745	RESPONSE REGULATOR receiver
VCA1552_00966	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VCA1552_00967	COG0072	phenylalanine-tRNA ligase activity
VCA1552_00967	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCA1552_00968	COG0776	regulation of translation
VCA1552_00971	COG0500	methyltransferase
VCA1552_00972	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
VCA1552_00974	COG0295	cytidine deaminase activity
VCA1552_00975	COG1346	cytolysis
VCA1552_00977	COG2925	Exonuclease
VCA1552_00979	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCA1552_00980	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VCA1552_00981	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VCA1552_00984	COG2988	succinylglutamate desuccinylase activity
VCA1552_00985	COG4139	cobalamin transport
VCA1552_00986	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
VCA1552_00995	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCA1552_00996	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCA1552_00997	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCA1552_01001	COG2814	Major facilitator Superfamily
VCA1552_01003	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VCA1552_01008	COG2989	Protein conserved in bacteria
VCA1552_01009	COG3108	Peptidase M15
VCA1552_01010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCA1552_01013	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCA1552_01018	COG1846	Transcriptional regulator
VCA1552_01019	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VCA1552_01020	COG0726	polysaccharide deacetylase
VCA1552_01021	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VCA1552_01023	COG1447	Phosphotransferase system cellobiose-specific component IIA
VCA1552_01024	COG1486	melibiose metabolic process
VCA1552_01025	COG3394	polysaccharide catabolic process
VCA1552_01026	COG1609	Transcriptional regulator
VCA1552_01027	COG2943	transferase activity, transferring hexosyl groups
VCA1552_01028	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
VCA1552_01029	COG0840	transmembrane signaling receptor activity
VCA1552_01032	COG1448	Aminotransferase
VCA1552_01036	COG0351	phosphomethylpyrimidine kinase
VCA1552_01037	COG0017	Asparaginyl-tRNA synthetase
VCA1552_01039	COG0720	synthase
VCA1552_01040	COG1760	l-serine dehydratase
VCA1552_01041	COG0814	amino acid
VCA1552_01042	COG0494	nUDIX hydrolase
VCA1552_01043	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCA1552_01046	COG3106	COG3106 Predicted ATPase
VCA1552_01047	COG3768	UPF0283 membrane protein
VCA1552_01048	COG3283	Transcriptional regulator of aromatic amino acids metabolism
VCA1552_01049	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCA1552_01052	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCA1552_01054	COG0471	metal ion transport
VCA1552_01055	COG4191	Histidine kinase
VCA1552_01055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCA1552_01057	COG2990	Protein conserved in bacteria
VCA1552_01058	COG3713	MltA-interacting MipA family protein
VCA1552_01059	COG2205	protein histidine kinase activity
VCA1552_01060	COG0745	RESPONSE REGULATOR receiver
VCA1552_01065	COG1129	ABC transporter
VCA1552_01072	COG2186	Transcriptional regulator
VCA1552_01073	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VCA1552_01074	COG0372	Belongs to the citrate synthase family
VCA1552_01081	COG1943	Transposase
VCA1552_01082	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCA1552_01084	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VCA1552_01086	COG0625	glutathione transferase activity
VCA1552_01087	COG3437	response regulator, receiver
VCA1552_01090	COG3706	GGDEF domain
VCA1552_01091	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCA1552_01092	COG1254	Belongs to the acylphosphatase family
VCA1552_01093	COG2920	part of a sulfur-relay system
VCA1552_01094	COG0670	Belongs to the BI1 family
VCA1552_01095	COG1126	abc transporter atp-binding protein
VCA1552_01096	COG0765	amino acid transport
VCA1552_01097	COG4597	amino acid ABC transporter
VCA1552_01098	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCA1552_01100	COG0561	phosphatase activity
VCA1552_01102	COG0602	queuosine metabolic process
VCA1552_01103	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VCA1552_01109	COG3706	GGDEF domain
VCA1552_01110	COG0443	Heat shock 70 kDa protein
VCA1552_01111	COG0443	Heat shock 70 kDa protein
VCA1552_01118	COG1643	Atp-dependent helicase
VCA1552_01120	COG0443	Heat shock 70 kDa protein
VCA1552_01121	COG0095	Lipoate-protein ligase
VCA1552_01122	COG0583	DNA-binding transcription factor activity
VCA1552_01123	COG0477	Major facilitator Superfamily
VCA1552_01124	COG0415	Belongs to the DNA photolyase family
VCA1552_01126	COG2076	Multidrug Resistance protein
VCA1552_01130	COG2198	Histidine kinase
VCA1552_01130	COG0643	Histidine kinase
VCA1552_01132	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCA1552_01134	COG2201	protein-glutamate methylesterase activity
VCA1552_01135	COG0835	chemotaxis
VCA1552_01136	COG3290	protein histidine kinase activity
VCA1552_01136	COG0840	transmembrane signaling receptor activity
VCA1552_01137	COG0840	transmembrane signaling receptor activity
VCA1552_01139	COG0513	Belongs to the DEAD box helicase family
VCA1552_01141	COG1538	Outer membrane efflux protein
VCA1552_01142	COG1566	PFAM secretion protein HlyD family protein
VCA1552_01143	COG2814	Major facilitator Superfamily
VCA1552_01144	COG0840	transmembrane signaling receptor activity
VCA1552_01145	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VCA1552_01147	COG3501	Rhs element vgr protein
VCA1552_01152	COG1280	lysine exporter protein (LysE YggA)
VCA1552_01153	COG1115	amino acid carrier protein
VCA1552_01157	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCA1552_01158	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCA1552_01159	COG1177	transmembrane transport
VCA1552_01160	COG1176	ABC-type spermidine putrescine transport system, permease component I
VCA1552_01161	COG3842	ATPase activity
VCA1552_01165	COG0037	tRNA processing
VCA1552_01166	COG0589	response to stress
VCA1552_01167	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VCA1552_01170	COG2217	Heavy metal translocating P-type atpase
VCA1552_01172	COG2010	Cytochrome c
VCA1552_01175	COG3278	Belongs to the heme-copper respiratory oxidase family
VCA1552_01178	COG2205	protein histidine kinase activity
VCA1552_01178	COG0784	Response regulator, receiver
VCA1552_01183	COG2994	toxin metabolic process
VCA1552_01184	COG1073	alpha beta
VCA1552_01184	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VCA1552_01184	COG3064	Membrane
VCA1552_01188	COG1476	TRANSCRIPTIONal
VCA1552_01191	COG4128	Pfam Zonular occludens toxin
VCA1552_01198	COG1476	TRANSCRIPTIONal
VCA1552_01215	COG3120	sequence-specific DNA binding
VCA1552_01216	COG1067	ATP-dependent peptidase activity
VCA1552_01217	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCA1552_01222	COG0116	Belongs to the methyltransferase superfamily
VCA1552_01222	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCA1552_01225	COG0167	dihydroorotate dehydrogenase activity
VCA1552_01227	COG0308	aminopeptidase N
VCA1552_01235	COG0641	radical SAM
VCA1552_01251	COG4695	Portal protein
VCA1552_01270	COG1428	Deoxynucleoside kinase
VCA1552_01285	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
VCA1552_01286	COG0308	aminopeptidase N
VCA1552_01289	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VCA1552_01290	COG1956	GAF domain-containing protein
VCA1552_01291	COG1132	(ABC) transporter
VCA1552_01292	COG2995	paraquat-inducible protein a
VCA1552_01293	COG3008	intermembrane lipid transfer
VCA1552_01294	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VCA1552_01294	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
VCA1552_01296	COG2996	Protein conserved in bacteria
VCA1552_01299	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCA1552_01301	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VCA1552_01304	COG0437	4 iron, 4 sulfur cluster binding
VCA1552_01305	COG0243	molybdopterin cofactor binding
VCA1552_01305	COG3383	formate dehydrogenase (NAD+) activity
VCA1552_01311	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VCA1552_01312	COG0488	(ABC) transporter
VCA1552_01313	COG3852	Histidine kinase
VCA1552_01314	COG2204	response regulator
VCA1552_01316	COG4662	Binding-protein-dependent transport system inner membrane component
VCA1552_01317	COG3842	ATPase activity
VCA1552_01318	COG0746	molybdenum cofactor guanylyltransferase activity
VCA1552_01323	COG1940	carbohydrate kinase activity
VCA1552_01326	COG0840	transmembrane signaling receptor activity
VCA1552_01327	COG0791	NLP P60 protein
VCA1552_01331	COG0534	Mate efflux family protein
VCA1552_01333	COG1793	dna ligase
VCA1552_01335	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCA1552_01336	COG0848	biopolymer transport protein
VCA1552_01337	COG0811	peptide transport
VCA1552_01338	COG0811	peptide transport
VCA1552_01341	COG1175	transmembrane transport
VCA1552_01342	COG0395	ABC-type sugar transport system, permease component
VCA1552_01343	COG3842	ATPase activity
VCA1552_01344	COG1349	DNA-binding transcription factor activity
VCA1552_01345	COG0584	glycerophosphoryl diester phosphodiesterase
VCA1552_01346	COG2731	YhcH YjgK YiaL family protein
VCA1552_01347	COG0251	oxidation-reduction process
VCA1552_01348	COG1609	Transcriptional regulator
VCA1552_01349	COG2723	6-phospho-beta-galactosidase activity
VCA1552_01350	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
VCA1552_01351	COG0583	DNA-binding transcription factor activity
VCA1552_01355	COG0577	efflux transmembrane transporter activity
VCA1552_01355	COG1136	(ABC) transporter
VCA1552_01356	COG1136	(ABC) transporter
VCA1552_01356	COG0577	efflux transmembrane transporter activity
VCA1552_01357	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCA1552_01357	COG1136	(ABC) transporter
VCA1552_01358	COG1294	oxidase, subunit
VCA1552_01359	COG1271	oxidase subunit
VCA1552_01367	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCA1552_01369	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCA1552_01373	COG0753	catalase activity
VCA1552_01376	COG3527	Alpha-acetolactate decarboxylase
VCA1552_01379	COG2200	EAL domain
VCA1552_01379	COG2199	diguanylate cyclase activity
VCA1552_01380	COG3706	GGDEF domain
VCA1552_01381	COG2017	converts alpha-aldose to the beta-anomer
VCA1552_01382	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VCA1552_01383	COG1085	galactose-1-phosphate uridylyltransferase
VCA1552_01388	COG3706	GGDEF domain
VCA1552_01388	COG0745	RESPONSE REGULATOR receiver
VCA1552_01391	COG0784	Response regulator, receiver
VCA1552_01391	COG0835	chemotaxis
VCA1552_01393	COG4565	transcriptional regulatory protein
VCA1552_01394	COG3290	protein histidine kinase activity
VCA1552_01397	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCA1552_01401	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VCA1552_01402	COG3063	Type IV pilus biogenesis stability protein PilW
VCA1552_01405	COG1451	nucleotide metabolic process
VCA1552_01407	COG0583	DNA-binding transcription factor activity
VCA1552_01411	COG1538	Outer membrane efflux protein
VCA1552_01413	COG0019	diaminopimelate decarboxylase activity
VCA1552_01414	COG1748	Saccharopine dehydrogenase
VCA1552_01416	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCA1552_01419	COG4181	ATPase activity
VCA1552_01420	COG0534	Mate efflux family protein
VCA1552_01421	COG0702	epimerase
VCA1552_01423	COG2814	Major facilitator Superfamily
VCA1552_01424	COG1187	pseudouridine synthase activity
VCA1552_01425	COG1061	Type III restriction enzyme res subunit
VCA1552_01429	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VCA1552_01430	COG3706	GGDEF domain
VCA1552_01430	COG2203	Gaf domain
VCA1552_01430	COG4251	negative regulation of phosphorylation
VCA1552_01430	COG5001	Diguanylate cyclase
VCA1552_01432	COG0840	transmembrane signaling receptor activity
VCA1552_01438	COG4934	collagen metabolic process
VCA1552_01443	COG2239	Acts as a magnesium transporter
VCA1552_01446	COG0814	amino acid
VCA1552_01447	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCA1552_01448	COG1131	(ABC) transporter
VCA1552_01449	COG0842	Transport permease protein
VCA1552_01451	COG3313	Fe-S protein
VCA1552_01453	COG4134	Bacterial extracellular solute-binding protein
VCA1552_01454	COG4135	transport system, permease component
VCA1552_01455	COG4136	ATPase activity
VCA1552_01456	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VCA1552_01457	COG0564	pseudouridine synthase activity
VCA1552_01458	COG0733	neurotransmitter:sodium symporter activity
VCA1552_01460	COG0626	cystathionine gamma-synthase activity
VCA1552_01461	COG2818	Glycosylase
VCA1552_01464	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCA1552_01467	COG1842	Phage shock protein A
VCA1552_01468	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VCA1552_01470	COG4168	peptide transport system, permease
VCA1552_01471	COG4171	peptide transport system, permease
VCA1552_01473	COG4172	Belongs to the ABC transporter superfamily
VCA1552_01476	COG1227	inorganic diphosphatase activity
VCA1552_01480	COG0243	molybdopterin cofactor binding
VCA1552_01481	COG3005	denitrification pathway
VCA1552_01482	COG4459	periplasmic nitrate reductase
VCA1552_01483	COG2116	formate transmembrane transporter activity
VCA1552_01485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCA1552_01486	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCA1552_01488	COG2917	probably involved in intracellular septation
VCA1552_01489	COG1607	acyl-coa hydrolase
VCA1552_01490	COG2350	Protein conserved in bacteria
VCA1552_01492	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VCA1552_01493	COG0583	DNA-binding transcription factor activity
VCA1552_01496	COG0612	Peptidase, M16
VCA1552_01498	COG1032	radical SAM domain protein
VCA1552_01501	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
VCA1552_01502	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VCA1552_01503	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VCA1552_01504	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCA1552_01505	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCA1552_01506	COG0745	RESPONSE REGULATOR receiver
VCA1552_01507	COG3381	protein complex oligomerization
VCA1552_01508	COG1609	Transcriptional regulator
VCA1552_01510	COG3070	regulator of competence-specific genes
VCA1552_01514	COG0297	glycogen (starch) synthase activity
VCA1552_01515	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCA1552_01516	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCA1552_01518	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
VCA1552_01519	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VCA1552_01520	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
VCA1552_01521	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VCA1552_01522	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCA1552_01528	COG1012	belongs to the aldehyde dehydrogenase family
VCA1552_01529	COG1309	transcriptional regulator
VCA1552_01533	COG0668	transmembrane transport
VCA1552_01534	COG2995	paraquat-inducible protein a
VCA1552_01535	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCA1552_01535	COG3008	intermembrane lipid transfer
VCA1552_01537	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCA1552_01540	COG0582	viral genome integration into host DNA
VCA1552_01541	COG0582	viral genome integration into host DNA
VCA1552_01542	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VCA1552_01546	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VCA1552_01550	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VCA1552_01554	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VCA1552_01555	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VCA1552_01556	COG1737	Transcriptional regulator
VCA1552_01557	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VCA1552_01558	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCA1552_01559	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCA1552_01560	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCA1552_01561	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
VCA1552_01562	COG1940	carbohydrate kinase activity
VCA1552_01563	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VCA1552_01564	COG4409	exo-alpha-(2->6)-sialidase activity
VCA1552_01566	COG2003	Belongs to the UPF0758 family
VCA1552_01571	COG3941	tape measure
VCA1552_01579	COG0488	(ABC) transporter
VCA1552_01594	COG0415	Belongs to the DNA photolyase family
VCA1552_01596	COG4628	conserved protein (DUF2132)
VCA1552_01597	COG3284	Transcriptional regulator
VCA1552_01598	COG1012	belongs to the aldehyde dehydrogenase family
VCA1552_01600	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCA1552_01601	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCA1552_01602	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCA1552_01604	COG2207	Transcriptional regulator
VCA1552_01605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCA1552_01605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCA1552_01605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCA1552_01606	COG1482	cell wall glycoprotein biosynthetic process
VCA1552_01608	COG0784	Response regulator, receiver
VCA1552_01608	COG5002	protein histidine kinase activity
VCA1552_01610	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VCA1552_01612	COG2885	chlorophyll binding
VCA1552_01613	COG0823	Involved in the tonB-independent uptake of proteins
VCA1552_01616	COG0811	peptide transport
VCA1552_01617	COG0824	Thioesterase
VCA1552_01618	COG4890	Cyd operon protein YbgT
VCA1552_01619	COG1294	oxidase, subunit
VCA1552_01620	COG1271	oxidase subunit
VCA1552_01622	COG2255	four-way junction helicase activity
VCA1552_01623	COG0632	four-way junction helicase activity
VCA1552_01624	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VCA1552_01625	COG0215	cysteine-tRNA ligase activity
VCA1552_01626	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCA1552_01627	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCA1552_01628	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCA1552_01630	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCA1552_01631	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCA1552_01632	COG1199	ATP-dependent helicase activity
VCA1552_01633	COG0730	response to heat
VCA1552_01634	COG3923	Primosomal replication protein n
VCA1552_01636	COG0840	transmembrane signaling receptor activity
VCA1552_01637	COG0708	Exodeoxyribonuclease III
VCA1552_01638	COG4160	amino acid transport
VCA1552_01639	COG4215	(ABC) transporter
VCA1552_01644	COG1882	Formate acetyltransferase
VCA1552_01646	COG0840	transmembrane signaling receptor activity
VCA1552_01647	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VCA1552_01649	COG3013	Belongs to the UPF0304 family
VCA1552_01650	COG2766	serine protein kinase
VCA1552_01651	COG2718	Belongs to the UPF0229 family
VCA1552_01652	COG2719	SpoVR family
VCA1552_01653	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VCA1552_01655	COG1663	tetraacyldisaccharide 4'-kinase activity
VCA1552_01656	COG1132	(ABC) transporter
VCA1552_01657	COG2333	competence protein COMEC
VCA1552_01657	COG0658	competence protein
VCA1552_01659	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCA1552_01660	COG1136	(ABC) transporter
VCA1552_01661	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCA1552_01663	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VCA1552_01667	COG1252	NADH dehydrogenase
VCA1552_01673	COG0537	adenosine 5'-monophosphoramidase activity
VCA1552_01676	COG2186	Transcriptional regulator
VCA1552_01677	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCA1552_01678	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VCA1552_01679	COG1674	ftsk spoiiie
VCA1552_01681	COG0686	Belongs to the AlaDH PNT family
VCA1552_01683	COG0583	DNA-binding transcription factor activity
VCA1552_01686	COG0284	orotidine-5'-phosphate decarboxylase activity
VCA1552_01687	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VCA1552_01688	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VCA1552_01689	COG0776	regulation of translation
VCA1552_01690	COG0539	negative regulation of cytoplasmic translation
VCA1552_01691	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VCA1552_01692	COG1555	photosystem II stabilization
VCA1552_01693	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCA1552_01694	COG0776	regulation of translation
VCA1552_01695	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VCA1552_01696	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VCA1552_01698	COG0544	peptidyl-prolyl cis-trans isomerase activity
VCA1552_01699	COG4191	Histidine kinase
VCA1552_01701	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCA1552_01702	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCA1552_01703	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCA1552_01704	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VCA1552_01707	COG5001	Diguanylate cyclase
VCA1552_01707	COG3300	MHYT domain
VCA1552_01709	COG4589	Belongs to the CDS family
VCA1552_01716	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VCA1552_01718	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCA1552_01722	COG0243	molybdopterin cofactor binding
VCA1552_01723	COG3005	denitrification pathway
VCA1552_01724	COG3325	Belongs to the glycosyl hydrolase 18 family
VCA1552_01724	COG3469	chitinase activity
VCA1552_01725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCA1552_01727	COG2951	lytic endotransglycosylase activity
VCA1552_01728	COG3100	YcgL domain-containing protein
VCA1552_01729	COG0850	regulation of cytokinetic process
VCA1552_01730	COG2894	cell division
VCA1552_01731	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VCA1552_01732	COG3015	lipoprotein NlpE involved in copper resistance
VCA1552_01737	COG0477	Major facilitator Superfamily
VCA1552_01738	COG0840	transmembrane signaling receptor activity
VCA1552_01739	COG1396	sequence-specific DNA binding
VCA1552_01740	COG3135	benzoate transporter
VCA1552_01742	COG1441	menaquinone biosynthetic process
VCA1552_01744	COG0596	Alpha beta hydrolase
VCA1552_01745	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VCA1552_01746	COG1169	isochorismate synthase
VCA1552_01747	COG0436	Aminotransferase
VCA1552_01748	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VCA1552_01749	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VCA1552_01753	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VCA1552_01754	COG0318	PFAM AMP-dependent synthetase and ligase
VCA1552_01755	COG0596	Alpha beta hydrolase
VCA1552_01758	COG1214	PFAM Peptidase M22, glycoprotease
VCA1552_01759	COG1199	ATP-dependent helicase activity
VCA1552_01761	COG0788	formyltetrahydrofolate deformylase activity
VCA1552_01762	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCA1552_01762	COG1902	pentaerythritol trinitrate reductase activity
VCA1552_01763	COG0616	signal peptide processing
VCA1552_01764	COG0252	asparaginase activity
VCA1552_01765	COG3139	Protein of unknown function (DUF1315)
VCA1552_01767	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCA1552_01768	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCA1552_01769	COG0676	glucose-6-phosphate 1-epimerase activity
VCA1552_01771	COG2226	methyltransferase
VCA1552_01774	COG0835	chemotaxis
VCA1552_01774	COG0784	Response regulator, receiver
VCA1552_01775	COG1940	carbohydrate kinase activity
VCA1552_01777	COG4667	esterase of the alpha-beta hydrolase superfamily
VCA1552_01780	COG0733	neurotransmitter:sodium symporter activity
VCA1552_01782	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCA1552_01782	COG1263	PTS System
VCA1552_01783	COG0084	hydrolase, TatD family'
VCA1552_01785	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VCA1552_01786	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VCA1552_01787	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCA1552_01788	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCA1552_01789	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VCA1552_01790	COG1028	Short-chain dehydrogenase reductase Sdr
VCA1552_01791	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
VCA1552_01792	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCA1552_01793	COG0416	fatty acid biosynthetic process
VCA1552_01794	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VCA1552_01795	COG1399	metal-binding, possibly nucleic acid-binding protein
VCA1552_01796	COG0424	maF-like protein
VCA1552_01797	COG0564	pseudouridine synthase activity
VCA1552_01798	COG1530	ribonuclease E activity
VCA1552_01799	COG0659	secondary active sulfate transmembrane transporter activity
VCA1552_01801	COG1012	belongs to the aldehyde dehydrogenase family
VCA1552_01801	COG1454	alcohol dehydrogenase
VCA1552_01802	COG2095	MarC family integral membrane protein
VCA1552_01803	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCA1552_01804	COG1757	Na H antiporter
VCA1552_01806	COG3081	Nucleoid-associated protein
VCA1552_01808	COG3083	sulfuric ester hydrolase activity
VCA1552_01811	COG0123	including yeast histone deacetylase and acetoin utilization protein
VCA1552_01812	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCA1552_01813	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VCA1552_01817	COG2853	Lipoprotein
VCA1552_01819	COG4235	cytochrome complex assembly
VCA1552_01819	COG3088	subunit of a heme lyase
VCA1552_01820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VCA1552_01821	COG1138	Cytochrome C-type biogenesis protein
VCA1552_01822	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VCA1552_01824	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCA1552_01825	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCA1552_01826	COG4133	protoheme IX ABC transporter activity
VCA1552_01828	COG0835	chemotaxis
VCA1552_01830	COG1192	Involved in chromosome partitioning
VCA1552_01831	COG2201	protein-glutamate methylesterase activity
VCA1552_01832	COG2198	Histidine kinase
VCA1552_01832	COG0643	Histidine kinase
VCA1552_01833	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VCA1552_01836	COG0455	bacterial-type flagellum organization
VCA1552_01839	COG2062	phosphohistidine phosphatase, SixA
VCA1552_01840	COG1025	Belongs to the peptidase M16 family
VCA1552_01842	COG0018	arginyl-trna synthetase
VCA1552_01846	COG1918	ferrous iron import across plasma membrane
VCA1552_01848	COG4977	sequence-specific DNA binding
VCA1552_01849	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VCA1552_01850	COG1121	(ABC) transporter
VCA1552_01851	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VCA1552_01853	COG0045	succinate-CoA ligase (ADP-forming) activity
VCA1552_01854	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCA1552_01855	COG0567	Dehydrogenase, E1 component
VCA1552_01857	COG1053	succinate dehydrogenase
VCA1552_01858	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VCA1552_01859	COG2009	succinate dehydrogenase
VCA1552_01860	COG0372	Belongs to the citrate synthase family
VCA1552_01861	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VCA1552_01863	COG0033	Phosphoglucomutase
VCA1552_01864	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VCA1552_01865	COG0596	Alpha beta hydrolase
VCA1552_01868	COG1346	cytolysis
VCA1552_01870	COG0583	DNA-binding transcription factor activity
VCA1552_01872	COG0735	belongs to the Fur family
VCA1552_01873	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCA1552_01874	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCA1552_01875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCA1552_01876	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VCA1552_01876	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VCA1552_01877	COG0431	NADPH-dependent FMN reductase
VCA1552_01879	COG3101	peptidyl-lysine hydroxylation
VCA1552_01880	COG2860	membrane
VCA1552_01881	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VCA1552_01882	COG2890	protein-(glutamine-N5) methyltransferase activity
VCA1552_01885	COG1684	flagellar biosynthetic protein fliR
VCA1552_01886	COG1987	bacterial-type flagellum assembly
VCA1552_01891	COG1580	Controls the rotational direction of flagella during chemotaxis
VCA1552_01895	COG1317	bacterial-type flagellum organization
VCA1552_01896	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VCA1552_01898	COG1677	Flagellar hook-basal body complex protein FliE
VCA1552_01899	COG2204	response regulator
VCA1552_01900	COG4191	Histidine kinase
VCA1552_01901	COG2204	response regulator
VCA1552_01902	COG1516	flagellar protein fliS
VCA1552_01904	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VCA1552_01905	COG1334	flagellar protein FlaG
VCA1552_01906	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCA1552_01907	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCA1552_01908	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCA1552_01909	COG2837	iron assimilation
VCA1552_01913	COG1393	Belongs to the ArsC family
VCA1552_01914	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VCA1552_01915	COG1876	peptidase activity
VCA1552_01917	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VCA1552_01918	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VCA1552_01920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VCA1552_01924	COG4783	chaperone-mediated protein folding
VCA1552_01925	COG1393	Belongs to the ArsC family
VCA1552_01929	COG2233	PERMEase
VCA1552_01930	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VCA1552_01931	COG0737	Belongs to the 5'-nucleotidase family
VCA1552_01932	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VCA1552_01933	COG2912	Transglutaminase-like superfamily
VCA1552_01934	COG3094	Invasion gene expression up-regulator, SirB
VCA1552_01935	COG2890	protein-(glutamine-N5) methyltransferase activity
VCA1552_01936	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VCA1552_01937	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VCA1552_01938	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VCA1552_01939	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VCA1552_01940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VCA1552_01941	COG0193	aminoacyl-tRNA hydrolase activity
VCA1552_01942	COG0012	GTP binding
VCA1552_01959	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCA1552_01960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCA1552_01963	COG3951	Flagellar rod assembly protein muramidase FlgJ
VCA1552_01963	COG1705	Flagellar rod assembly protein muramidase FlgJ
VCA1552_01964	COG1706	bacterial-type flagellum-dependent cell motility
VCA1552_01965	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VCA1552_01966	COG4786	Flagellar basal body rod
VCA1552_01967	COG4787	bacterial-type flagellum-dependent cell motility
VCA1552_01968	COG1749	Flagellar hook protein flgE
VCA1552_01969	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
VCA1552_01970	COG1558	bacterial-type flagellum-dependent cell motility
VCA1552_01971	COG1815	bacterial-type flagellum-dependent cell motility
VCA1552_01972	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCA1552_01973	COG0784	Response regulator, receiver
VCA1552_01973	COG0835	chemotaxis
VCA1552_01980	COG2226	methyltransferase
VCA1552_01980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCA1552_01980	COG3433	isochorismatase activity
VCA1552_01981	COG2375	cellular response to nickel ion
VCA1552_01982	COG4774	siderophore transport
VCA1552_01982	COG1629	transport
VCA1552_01985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCA1552_01986	COG2217	Heavy metal translocating P-type atpase
VCA1552_01986	COG2608	mercury ion transmembrane transporter activity
VCA1552_01989	COG3735	TraB family
VCA1552_01992	COG2840	Smr protein MutS2
VCA1552_01993	COG1187	pseudouridine synthase activity
VCA1552_01994	COG3706	GGDEF domain
VCA1552_01996	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VCA1552_01997	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VCA1552_01998	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VCA1552_01999	COG0121	glutamine amidotransferase
VCA1552_02000	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCA1552_02001	COG1960	acyl-CoA dehydrogenase activity
VCA1552_02003	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VCA1552_02004	COG0328	RNA-DNA hybrid ribonuclease activity
VCA1552_02005	COG2226	methyltransferase
VCA1552_02006	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCA1552_02007	COG0741	lytic transglycosylase activity
VCA1552_02007	COG1388	LysM domain
VCA1552_02009	COG0347	Belongs to the P(II) protein family
VCA1552_02010	COG3479	Phenolic acid decarboxylase
VCA1552_02012	COG0037	tRNA processing
VCA1552_02013	COG0825	malonyl-CoA metabolic process
VCA1552_02014	COG0587	DNA-directed DNA polymerase activity
VCA1552_02015	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
VCA1552_02016	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCA1552_02017	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCA1552_02018	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCA1552_02019	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCA1552_02020	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VCA1552_02022	COG0750	zinc metalloprotease
VCA1552_02023	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VCA1552_02024	COG0575	Belongs to the CDS family
VCA1552_02025	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VCA1552_02026	COG0233	cytoplasmic translational termination
VCA1552_02027	COG0528	UMP kinase activity
VCA1552_02028	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VCA1552_02029	COG0052	Belongs to the universal ribosomal protein uS2 family
VCA1552_02031	COG0024	Methionine aminopeptidase
VCA1552_02032	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VCA1552_02034	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VCA1552_02035	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VCA1552_02036	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCA1552_02037	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VCA1552_02040	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCA1552_02040	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCA1552_02041	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VCA1552_02042	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VCA1552_02043	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VCA1552_02046	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VCA1552_02047	COG2252	PERMEase
VCA1552_02048	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCA1552_02049	COG4067	protein conserved in archaea
VCA1552_02049	COG0189	ligase activity
VCA1552_02050	COG0189	ligase activity
VCA1552_02052	COG0733	neurotransmitter:sodium symporter activity
VCA1552_02053	COG3706	GGDEF domain
VCA1552_02055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VCA1552_02057	COG1477	protein flavinylation
VCA1552_02058	COG2871	sodium ion transport
VCA1552_02059	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCA1552_02060	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCA1552_02061	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCA1552_02062	COG1805	sodium ion transport
VCA1552_02063	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCA1552_02064	COG0271	Belongs to the BolA IbaG family
VCA1552_02065	COG2813	Specifically methylates the guanine in position
VCA1552_02067	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCA1552_02068	COG2211	Major facilitator Superfamily
VCA1552_02070	COG1595	DNA-templated transcription, initiation
VCA1552_02072	COG3248	Nucleoside-binding outer membrane protein
VCA1552_02073	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VCA1552_02074	COG0693	protein deglycase activity
VCA1552_02075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCA1552_02076	COG2166	iron-sulfur cluster assembly
VCA1552_02077	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VCA1552_02078	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VCA1552_02080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCA1552_02080	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VCA1552_02082	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VCA1552_02083	COG1074	ATP-dependent DNA helicase activity
VCA1552_02084	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VCA1552_02087	COG3141	response to X-ray
VCA1552_02088	COG2171	N-acyltransferase activity
VCA1552_02090	COG0456	acetyltransferase
VCA1552_02092	COG0569	domain protein
VCA1552_02092	COG0189	ligase activity
VCA1552_02095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCA1552_02096	COG1609	Transcriptional regulator
VCA1552_02097	COG3250	beta-galactosidase activity
VCA1552_02100	COG1022	Amp-dependent synthetase and ligase
VCA1552_02101	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCA1552_02102	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VCA1552_02104	COG0560	Phosphoserine phosphatase
VCA1552_02106	COG0813	purine-nucleoside phosphorylase activity
VCA1552_02107	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VCA1552_02108	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VCA1552_02109	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VCA1552_02110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCA1552_02111	COG0084	hydrolase, TatD family'
VCA1552_02114	COG1115	amino acid carrier protein
VCA1552_02117	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VCA1552_02118	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VCA1552_02119	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VCA1552_02120	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VCA1552_02121	COG0083	homoserine kinase activity
VCA1552_02125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCA1552_02127	COG0745	RESPONSE REGULATOR receiver
VCA1552_02128	COG2198	Histidine kinase
VCA1552_02128	COG0784	Response regulator, receiver
VCA1552_02128	COG5002	protein histidine kinase activity
VCA1552_02129	COG2203	Gaf domain
VCA1552_02129	COG3706	GGDEF domain
VCA1552_02129	COG5001	Diguanylate cyclase
VCA1552_02129	COG4251	negative regulation of phosphorylation
VCA1552_02130	COG1242	4 iron, 4 sulfur cluster binding
VCA1552_02131	COG0067	glutamate synthase
VCA1552_02131	COG0070	glutamate synthase
VCA1552_02131	COG0069	glutamate synthase activity
VCA1552_02133	COG0067	glutamate synthase
VCA1552_02133	COG0069	glutamate synthase activity
VCA1552_02133	COG0070	glutamate synthase
VCA1552_02134	COG0493	'glutamate synthase
VCA1552_02136	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VCA1552_02138	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VCA1552_02139	COG2860	membrane
VCA1552_02140	COG0583	DNA-binding transcription factor activity
VCA1552_02141	COG0730	response to heat
VCA1552_02144	COG4172	Belongs to the ABC transporter superfamily
VCA1552_02148	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VCA1552_02149	COG0505	Belongs to the CarA family
VCA1552_02150	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
VCA1552_02151	COG0494	nUDIX hydrolase
VCA1552_02152	COG0653	protein targeting
VCA1552_02154	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VCA1552_02155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VCA1552_02156	COG0849	cell division
VCA1552_02157	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VCA1552_02158	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCA1552_02159	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
VCA1552_02160	COG0772	Belongs to the SEDS family
VCA1552_02161	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VCA1552_02162	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VCA1552_02163	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VCA1552_02164	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VCA1552_02165	COG0768	penicillin binding
VCA1552_02166	COG3116	cell division
VCA1552_02167	COG0275	rRNA processing
VCA1552_02169	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCA1552_02170	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCA1552_02171	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VCA1552_02172	COG2186	Transcriptional regulator
VCA1552_02173	COG0737	Belongs to the 5'-nucleotidase family
VCA1552_02174	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VCA1552_02175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCA1552_02176	COG4974	Belongs to the 'phage' integrase family
VCA1552_02177	COG0716	FMN binding
VCA1552_02181	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCA1552_02182	COG1459	type II secretion system
VCA1552_02184	COG0237	dephospho-CoA kinase activity
VCA1552_02185	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VCA1552_02186	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
VCA1552_02187	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VCA1552_02188	COG0187	DNA topoisomerase II activity
VCA1552_02189	COG3150	esterase
VCA1552_02191	COG3151	Protein conserved in bacteria
VCA1552_02192	COG0494	nUDIX hydrolase
VCA1552_02193	COG1538	Outer membrane efflux protein
VCA1552_02195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VCA1552_02196	COG0840	transmembrane signaling receptor activity
VCA1552_02198	COG3025	triphosphatase activity
VCA1552_02199	COG1392	Phosphate transport regulator
VCA1552_02200	COG0306	phosphate transporter
VCA1552_02201	COG4991	sh3 domain protein
VCA1552_02203	COG3409	Peptidoglycan-binding domain 1 protein
VCA1552_02203	COG3267	Type II secretory pathway component ExeA
VCA1552_02204	COG0617	tRNA 3'-terminal CCA addition
VCA1552_02205	COG0148	phosphopyruvate hydratase activity
VCA1552_02206	COG0504	CTP synthase activity
VCA1552_02207	COG3956	TIGRFAM MazG family protein
VCA1552_02208	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCA1552_02209	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCA1552_02211	COG5001	Diguanylate cyclase
VCA1552_02214	COG0736	holo-[acyl-carrier-protein] synthase activity
VCA1552_02215	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VCA1552_02216	COG1381	Involved in DNA repair and RecF pathway recombination
VCA1552_02217	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VCA1552_02218	COG0571	ribonuclease III activity
VCA1552_02219	COG0681	Belongs to the peptidase S26 family
VCA1552_02220	COG0481	GTPase activity
VCA1552_02221	COG3086	response to oxidative stress
VCA1552_02222	COG3026	antisigma factor binding
VCA1552_02224	COG1595	DNA-templated transcription, initiation
VCA1552_02225	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VCA1552_02227	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VCA1552_02228	COG0354	folic acid binding
VCA1552_02230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCA1552_02231	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCA1552_02233	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VCA1552_02235	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VCA1552_02236	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VCA1552_02237	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCA1552_02238	COG0440	acetolactate synthase activity
VCA1552_02239	COG0028	Belongs to the TPP enzyme family
VCA1552_02240	COG1022	Amp-dependent synthetase and ligase
VCA1552_02241	COG0583	DNA-binding transcription factor activity
VCA1552_02245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VCA1552_02246	COG0473	3-isopropylmalate dehydrogenase activity
VCA1552_02247	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
VCA1552_02248	COG0066	3-isopropylmalate dehydratase activity
VCA1552_02257	COG3437	response regulator, receiver
VCA1552_02260	COG0795	lipopolysaccharide-transporting ATPase activity
VCA1552_02261	COG0795	lipopolysaccharide-transporting ATPase activity
VCA1552_02262	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCA1552_02263	COG2927	DNA polymerase III (CHI subunit)
VCA1552_02264	COG0525	valine-tRNA ligase activity
VCA1552_02265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCA1552_02266	COG0564	pseudouridine synthase activity
VCA1552_02267	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VCA1552_02268	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VCA1552_02269	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
VCA1552_02270	COG0540	Belongs to the ATCase OTCase family
VCA1552_02271	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
VCA1552_02272	COG0251	oxidation-reduction process
VCA1552_02273	COG0204	Acyl-transferase
VCA1552_02274	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VCA1552_02275	COG5007	Belongs to the BolA IbaG family
VCA1552_02277	COG2854	intermembrane phospholipid transfer
VCA1552_02278	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCA1552_02279	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VCA1552_02280	COG1127	ABC transporter
VCA1552_02282	COG0517	IMP dehydrogenase activity
VCA1552_02282	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VCA1552_02285	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VCA1552_02286	COG1137	ATPase activity
VCA1552_02288	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCA1552_02289	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCA1552_02290	COG1660	Displays ATPase and GTPase activities
VCA1552_02291	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCA1552_02292	COG2239	Acts as a magnesium transporter
VCA1552_02293	COG0312	modulator of DNA gyrase
VCA1552_02294	COG3028	Belongs to the UPF0307 family
VCA1552_02295	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VCA1552_02296	COG1178	ABC-type Fe3 transport system permease component
VCA1552_02297	COG4143	(ABC) transporter
VCA1552_02298	COG0163	prenyltransferase activity
VCA1552_02299	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCA1552_02300	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
VCA1552_02301	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VCA1552_02302	COG2105	PFAM AIG2 family protein
VCA1552_02304	COG0729	surface antigen
VCA1552_02305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCA1552_02306	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VCA1552_02309	COG1136	(ABC) transporter
VCA1552_02313	COG0529	Catalyzes the synthesis of activated sulfate
VCA1552_02314	COG2895	sulfate adenylyltransferase (ATP) activity
VCA1552_02315	COG0175	sulfate reduction
VCA1552_02316	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VCA1552_02316	COG1648	precorrin-2 dehydrogenase activity
VCA1552_02317	COG0737	Belongs to the 5'-nucleotidase family
VCA1552_02319	COG0513	Belongs to the DEAD box helicase family
VCA1552_02320	COG2153	protein acetylation
VCA1552_02321	COG0697	spore germination
VCA1552_02322	COG3061	Opacity-associated protein A
VCA1552_02322	COG3266	domain, Protein
VCA1552_02323	COG0545	Peptidyl-prolyl cis-trans isomerase
VCA1552_02325	COG0203	ribosomal protein L17
VCA1552_02326	COG0202	RNA polymerase activity
VCA1552_02327	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VCA1552_02328	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VCA1552_02329	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VCA1552_02332	COG0201	protein transport
VCA1552_02333	COG0200	Binds to the 23S rRNA
VCA1552_02334	COG1841	ribosomal large subunit assembly
VCA1552_02335	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VCA1552_02336	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VCA1552_02337	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
VCA1552_02338	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VCA1552_02339	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VCA1552_02340	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VCA1552_02341	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VCA1552_02342	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VCA1552_02343	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VCA1552_02344	COG0255	Belongs to the universal ribosomal protein uL29 family
VCA1552_02345	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VCA1552_02346	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VCA1552_02347	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VCA1552_02348	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VCA1552_02349	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VCA1552_02350	COG0089	rRNA binding
VCA1552_02351	COG0088	Forms part of the polypeptide exit tunnel
VCA1552_02352	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VCA1552_02353	COG0051	transcription antitermination factor activity, RNA binding
VCA1552_02354	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCA1552_02355	COG0557	exoribonuclease II activity
VCA1552_02356	COG3083	sulfuric ester hydrolase activity
VCA1552_02357	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VCA1552_02358	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VCA1552_02360	COG1047	Peptidyl-prolyl cis-trans
VCA1552_02363	COG2249	NAD(P)H dehydrogenase (quinone) activity
VCA1552_02364	COG0488	(ABC) transporter
VCA1552_02366	COG0429	hydrolase of the alpha beta-hydrolase fold
VCA1552_02368	COG3954	Phosphoribulokinase
VCA1552_02369	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VCA1552_02371	COG1012	belongs to the aldehyde dehydrogenase family
VCA1552_02373	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VCA1552_02375	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCA1552_02378	COG0180	Tryptophanyl-tRNA synthetase
VCA1552_02379	COG0546	phosphoglycolate phosphatase activity
VCA1552_02380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VCA1552_02381	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VCA1552_02383	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VCA1552_02384	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VCA1552_02390	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VCA1552_02392	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCA1552_02392	COG0678	peroxiredoxin activity
VCA1552_02393	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCA1552_02395	COG0165	Argininosuccinate lyase
VCA1552_02396	COG0137	argininosuccinate synthase activity
VCA1552_02397	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCA1552_02398	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VCA1552_02399	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VCA1552_02400	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VCA1552_02402	COG1045	serine acetyltransferase
VCA1552_02403	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VCA1552_02404	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VCA1552_02405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCA1552_02406	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VCA1552_02407	COG1053	succinate dehydrogenase
VCA1552_02408	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VCA1552_02409	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VCA1552_02410	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VCA1552_02411	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCA1552_02412	COG1509	lysine 2,3-aminomutase activity
VCA1552_02414	COG0459	protein refolding
VCA1552_02415	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCA1552_02420	COG0149	triose-phosphate isomerase activity
VCA1552_02422	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCA1552_02423	COG1575	Belongs to the MenA family. Type 1 subfamily
VCA1552_02424	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VCA1552_02425	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VCA1552_02426	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCA1552_02427	COG1609	Transcriptional regulator
VCA1552_02428	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VCA1552_02429	COG0254	rRNA binding
VCA1552_02430	COG0281	malic enzyme
VCA1552_02431	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
VCA1552_02432	COG0626	cystathionine gamma-synthase activity
VCA1552_02433	COG0527	aspartate kinase activity
VCA1552_02433	COG0460	homoserine dehydrogenase
VCA1552_02434	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VCA1552_02435	COG3074	FtsZ-dependent cytokinesis
VCA1552_02436	COG1494	fructose-1,6-bisphosphatase
VCA1552_02437	COG0205	6-phosphofructokinase activity
VCA1552_02438	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VCA1552_02440	COG0745	RESPONSE REGULATOR receiver
VCA1552_02441	COG2205	protein histidine kinase activity
VCA1552_02443	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VCA1552_02444	COG3030	protein affecting phage T7 exclusion by the F plasmid
VCA1552_02445	COG3706	GGDEF domain
VCA1552_02446	COG1027	Aspartate ammonia-lyase
VCA1552_02447	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCA1552_02450	COG4232	protein-disulfide reductase activity
VCA1552_02452	COG3263	regulation of cellular component size
VCA1552_02454	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCA1552_02455	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VCA1552_02456	COG0194	GDP metabolic process
VCA1552_02457	COG1758	RNA polymerase activity
VCA1552_02458	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCA1552_02459	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VCA1552_02460	COG2233	PERMEase
VCA1552_02462	COG0745	RESPONSE REGULATOR receiver
VCA1552_02463	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCA1552_02464	COG2183	response to ionizing radiation
VCA1552_02466	COG0596	Alpha beta hydrolase
VCA1552_02467	COG1040	competence protein
VCA1552_02468	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
VCA1552_02468	COG0316	Belongs to the HesB IscA family
VCA1552_02469	COG0494	nUDIX hydrolase
VCA1552_02470	COG1218	3'(2'),5'-bisphosphate nucleotidase
VCA1552_02472	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCA1552_02473	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCA1552_02474	COG3156	type II secretion system protein K
VCA1552_02475	COG4795	General secretion pathway protein
VCA1552_02476	COG2165	general secretion pathway protein
VCA1552_02477	COG2165	general secretion pathway protein
VCA1552_02478	COG2165	general secretion pathway protein
VCA1552_02479	COG1459	type II secretion system
VCA1552_02480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCA1552_02482	COG3031	protein transport across the cell outer membrane
VCA1552_02483	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VCA1552_02484	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VCA1552_02485	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
VCA1552_02487	COG0456	acetyltransferase
VCA1552_02488	COG1490	D-aminoacyl-tRNA deacylase activity
VCA1552_02493	COG0174	glutamine synthetase
VCA1552_02495	COG3852	Histidine kinase
VCA1552_02497	COG5001	Diguanylate cyclase
VCA1552_02497	COG3300	MHYT domain
VCA1552_02498	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VCA1552_02512	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
VCA1552_02513	COG1404	Belongs to the peptidase S8 family
VCA1552_02514	COG4206	TonB-dependent receptor
VCA1552_02516	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCA1552_02519	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCA1552_02520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCA1552_02521	COG2177	Part of the ABC transporter FtsEX involved in
VCA1552_02522	COG2884	Cell division ATP-binding protein ftsE
VCA1552_02523	COG0552	protein localization to endoplasmic reticulum
VCA1552_02524	COG0742	ribosomal rna small subunit methyltransferase
VCA1552_02529	COG0783	Belongs to the Dps family
VCA1552_02530	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCA1552_02531	COG1280	lysine exporter protein (LysE YggA)
VCA1552_02532	COG2267	carboxylic ester hydrolase activity
VCA1552_02533	COG0561	phosphatase activity
VCA1552_02536	COG2200	EAL domain
VCA1552_02536	COG3287	FIST C domain
VCA1552_02536	COG2199	diguanylate cyclase activity
VCA1552_02537	COG1011	Hydrolase
VCA1552_02538	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VCA1552_02540	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VCA1552_02541	COG0019	diaminopimelate decarboxylase activity
VCA1552_02542	COG1965	Belongs to the frataxin family
VCA1552_02543	COG3072	Adenylate cyclase
VCA1552_02544	COG0181	hydroxymethylbilane synthase activity
VCA1552_02545	COG1587	Uroporphyrinogen-III synthase
VCA1552_02546	COG2959	enzyme of heme biosynthesis
VCA1552_02547	COG3071	HemY protein
VCA1552_02548	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VCA1552_02550	COG3078	GTPase activator activity
VCA1552_02553	COG0218	Necessary for normal cell division and for the maintenance of normal septation
VCA1552_02555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCA1552_02555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCA1552_02559	COG0084	hydrolase, TatD family'
VCA1552_02560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCA1552_02562	COG0840	transmembrane signaling receptor activity
VCA1552_02563	COG1580	Controls the rotational direction of flagella during chemotaxis
VCA1552_02564	COG3161	chorismate lyase activity
VCA1552_02565	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VCA1552_02566	COG2937	Belongs to the GPAT DAPAT family
VCA1552_02567	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VCA1552_02569	COG0534	Mate efflux family protein
VCA1552_02570	COG1858	cytochrome C peroxidase
VCA1552_02571	COG0805	protein transport
VCA1552_02572	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCA1552_02573	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCA1552_02574	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
VCA1552_02576	COG2226	methyltransferase
VCA1552_02577	COG1322	Protein conserved in bacteria
VCA1552_02579	COG2081	HI0933 family
VCA1552_02581	COG1528	Iron-storage protein
VCA1552_02582	COG0589	response to stress
VCA1552_02583	COG0697	spore germination
VCA1552_02585	COG0742	ribosomal rna small subunit methyltransferase
VCA1552_02586	COG5001	Diguanylate cyclase
VCA1552_02586	COG5002	protein histidine kinase activity
VCA1552_02587	COG1522	sequence-specific DNA binding
VCA1552_02591	COG0006	proline dipeptidase activity
VCA1552_02591	COG0006	proline dipeptidase activity
VCA1552_02592	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCA1552_02593	COG2022	thiamine diphosphate biosynthetic process
VCA1552_02594	COG2104	thiamine diphosphate biosynthetic process
VCA1552_02595	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCA1552_02597	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VCA1552_02599	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VCA1552_02609	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VCA1552_02611	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
VCA1552_02612	COG3118	belongs to the thioredoxin family
VCA1552_02613	COG0513	Belongs to the DEAD box helicase family
VCA1552_02614	COG0248	Ppx GppA phosphatase
VCA1552_02615	COG2205	protein histidine kinase activity
VCA1552_02615	COG0784	Response regulator, receiver
VCA1552_02616	COG2814	Major facilitator Superfamily
VCA1552_02619	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCA1552_02620	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VCA1552_02621	COG0511	ligase activity, forming carbon-carbon bonds
VCA1552_02622	COG0439	Biotin carboxylase
VCA1552_02623	COG2264	protein methyltransferase activity
VCA1552_02624	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCA1552_02625	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VCA1552_02626	COG1609	Transcriptional regulator
VCA1552_02627	COG0129	dihydroxy-acid dehydratase activity
VCA1552_02628	COG3265	gluconokinase activity
VCA1552_02630	COG0800	Aldolase
VCA1552_02634	COG0840	transmembrane signaling receptor activity
VCA1552_02635	COG1982	Orn Lys Arg decarboxylase major
VCA1552_02636	COG0531	amino acid
VCA1552_02639	COG0789	Transcriptional regulator
VCA1552_02640	COG0138	bifunctional purine biosynthesis protein purh
VCA1552_02641	COG0151	Belongs to the GarS family
VCA1552_02643	COG0776	regulation of translation
VCA1552_02644	COG1253	flavin adenine dinucleotide binding
VCA1552_02645	COG1940	carbohydrate kinase activity
VCA1552_02647	COG3068	Protein conserved in bacteria
VCA1552_02649	COG1573	uracil-dna glycosylase
VCA1552_02650	COG0668	transmembrane transport
VCA1552_02651	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VCA1552_02652	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCA1552_02661	COG1454	alcohol dehydrogenase
VCA1552_02661	COG1012	belongs to the aldehyde dehydrogenase family
VCA1552_02662	COG0318	PFAM AMP-dependent synthetase and ligase
VCA1552_02668	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
VCA1552_02669	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCA1552_02670	COG0662	Cupin 2, conserved barrel domain protein
VCA1552_02670	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
VCA1552_02671	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCA1552_02678	COG1519	Transferase
VCA1552_02684	COG3642	lipopolysaccharide core region biosynthetic process
VCA1552_02685	COG0859	PFAM glycosyl transferase family 9
VCA1552_02686	COG0463	Glycosyl transferase, family 2
VCA1552_02687	COG0859	PFAM glycosyl transferase family 9
VCA1552_02688	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VCA1552_02689	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VCA1552_02691	COG0267	Belongs to the bacterial ribosomal protein bL33 family
VCA1552_02692	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VCA1552_02695	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VCA1552_02696	COG1309	transcriptional regulator
VCA1552_02697	COG1560	Kdo2-lipid A biosynthetic process
VCA1552_02698	COG1560	Kdo2-lipid A biosynthetic process
VCA1552_02699	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VCA1552_02700	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VCA1552_02701	COG1561	YicC-like family, N-terminal region
VCA1552_02703	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCA1552_02703	COG1263	PTS System
VCA1552_02704	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCA1552_02708	COG1120	ATPase activity
VCA1552_02709	COG4774	siderophore transport
VCA1552_02710	COG1132	(ABC) transporter
VCA1552_02713	COG0514	ATP-dependent DNA helicase (RecQ)
VCA1552_02714	COG2962	Rard protein
VCA1552_02717	COG1280	lysine exporter protein (LysE YggA)
VCA1552_02719	COG0210	DNA helicase
VCA1552_02721	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VCA1552_02722	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCA1552_02739	COG2131	deaminase
VCA1552_02741	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCA1552_02743	COG0747	negative chemotaxis
VCA1552_02752	COG1309	transcriptional regulator
VCA1552_02753	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCA1552_02754	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCA1552_02755	COG2960	long-chain fatty acid transporting porin activity
VCA1552_02756	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VCA1552_02757	COG0583	DNA-binding transcription factor activity
VCA1552_02765	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
VCA1552_02766	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCA1552_02767	COG1739	Uncharacterized protein family UPF0029
VCA1552_02768	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCA1552_02768	COG1024	Enoyl-CoA hydratase
VCA1552_02769	COG0183	Belongs to the thiolase family
VCA1552_02770	COG0583	DNA-binding transcription factor activity
VCA1552_02771	COG2814	Major facilitator Superfamily
VCA1552_02772	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VCA1552_02773	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VCA1552_02774	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VCA1552_02775	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VCA1552_02776	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VCA1552_02777	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VCA1552_02778	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VCA1552_02780	COG0356	it plays a direct role in the translocation of protons across the membrane
VCA1552_02781	COG3312	ion transport
VCA1552_02782	COG1475	DNA binding
VCA1552_02783	COG1192	Involved in chromosome partitioning
VCA1552_02784	COG0357	Ribosomal RNA small subunit methyltransferase G
VCA1552_02785	COG0445	tRNA wobble uridine modification
VCA1552_02786	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCA1552_02787	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
VCA1552_02788	COG0706	membrane insertase activity
VCA1552_02789	COG0594	ribonuclease P activity
VCA1552_02790	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VCA1552_02791	COG1126	abc transporter atp-binding protein
VCA1552_02798	COG0217	transcriptional regulatory protein
VCA1552_02799	COG2084	Dehydrogenase
VCA1552_02802	COG2909	trisaccharide binding
VCA1552_02803	COG0058	SHG alpha-glucan phosphorylase activity
VCA1552_02804	COG1640	4-alpha-glucanotransferase
VCA1552_02805	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VCA1552_02807	COG3501	Rhs element vgr protein
VCA1552_02814	COG0471	metal ion transport
VCA1552_02815	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCA1552_02824	COG0671	phosphoesterase, PA-phosphatase related
VCA1552_02825	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VCA1552_02827	COG1999	signal sequence binding
VCA1552_02831	COG0786	glutamate:sodium symporter activity
VCA1552_02835	COG1566	PFAM secretion protein HlyD family protein
VCA1552_02837	COG3706	GGDEF domain
VCA1552_02840	COG0813	purine-nucleoside phosphorylase activity
VCA1552_02841	COG3272	Protein of unknown function (DUF1722)
VCA1552_02843	COG0415	Belongs to the DNA photolyase family
VCA1552_02844	COG1376	ErfK ybiS ycfS ynhG family protein
VCA1552_02844	COG1388	LysM domain
VCA1552_02846	COG0513	Belongs to the DEAD box helicase family
VCA1552_02847	COG1770	oligopeptidase
VCA1552_02853	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCA1552_02854	COG0573	inorganic phosphate transmembrane transporter activity
VCA1552_02855	COG0581	inorganic phosphate transmembrane transporter activity
VCA1552_02856	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCA1552_02860	COG0659	secondary active sulfate transmembrane transporter activity
VCA1552_02862	COG0739	heme binding
VCA1552_02863	COG5001	Diguanylate cyclase
VCA1552_02863	COG3300	MHYT domain
VCA1552_02865	COG0583	DNA-binding transcription factor activity
VCA1552_02866	COG2814	Major facilitator Superfamily
VCA1552_02871	COG1301	dicarboxylic acid transport
VCA1552_02873	COG1342	Belongs to the UPF0251 family
VCA1552_02879	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VCA1552_02880	COG0673	inositol 2-dehydrogenase activity
VCA1552_02882	COG2200	EAL domain
VCA1552_02882	COG2771	luxR family
VCA1552_02883	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCA1552_02885	COG0564	pseudouridine synthase activity
VCA1552_02903	COG3501	Rhs element vgr protein
VCA1552_02906	COG1869	D-ribose catabolic process
VCA1552_02907	COG1129	ABC transporter
VCA1552_02908	COG1172	Belongs to the binding-protein-dependent transport system permease family
VCA1552_02909	COG1879	ABC-type sugar transport system periplasmic component
VCA1552_02910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCA1552_02911	COG1609	Transcriptional regulator
VCA1552_02913	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCA1552_02915	COG0584	glycerophosphoryl diester phosphodiesterase
VCA1552_02916	COG2271	Major facilitator Superfamily
VCA1552_02923	COG0579	oxidoreductase
VCA1552_02925	COG0242	peptide deformylase activity
VCA1552_02927	COG1320	monovalent cation:proton antiporter activity
VCA1552_02928	COG2212	antiporter activity
VCA1552_02932	COG2111	Na H antiporter
VCA1552_02932	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCA1552_02934	COG0589	response to stress
VCA1552_02935	COG0814	amino acid
VCA1552_02936	COG3033	Beta-eliminating lyase
VCA1552_02938	COG3530	Putative quorum-sensing-regulated virulence factor
VCA1552_02940	COG5002	protein histidine kinase activity
VCA1552_02940	COG5001	Diguanylate cyclase
VCA1552_02942	COG1278	Cold shock
VCA1552_02945	COG2304	oxidoreductase activity
VCA1552_02949	COG0714	Associated with various cellular activities
VCA1552_02950	COG0840	transmembrane signaling receptor activity
VCA1552_02953	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCA1552_02954	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCA1552_02956	COG3604	Transcriptional regulator
VCA1552_02957	COG1017	nitric oxide dioxygenase activity
VCA1552_02957	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCA1552_02959	COG1278	Cold shock
VCA1552_02960	COG3036	rescue of stalled ribosome
VCA1552_02965	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VCA1552_02965	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VCA1552_02966	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCA1552_02968	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCA1552_02970	COG0516	GMP reductase activity
VCA1552_02975	COG1943	Transposase
VCA1552_02976	COG0513	Belongs to the DEAD box helicase family
VCA1552_02977	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCA1552_02978	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VCA1552_02979	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VCA1552_02981	COG3437	response regulator, receiver
VCA1552_02981	COG0784	Response regulator, receiver
VCA1552_02982	COG4191	Histidine kinase
VCA1552_02982	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCA1552_02984	COG1757	Na H antiporter
VCA1552_02986	COG2814	Major facilitator Superfamily
VCA1552_02987	COG3706	GGDEF domain
VCA1552_02988	COG3240	lipase activity
VCA1552_02990	COG0840	transmembrane signaling receptor activity
VCA1552_02991	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VCA1552_02992	COG5380	lipid catabolic process
VCA1552_02993	COG4412	M6 family metalloprotease domain protein
VCA1552_02993	COG3291	Pkd domain containing protein
VCA1552_02997	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCA1552_02998	COG4605	iron ion homeostasis
VCA1552_02999	COG4604	ABC transporter, ATP-binding protein
VCA1552_03003	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCA1552_03007	COG0745	RESPONSE REGULATOR receiver
VCA1552_03009	COG3623	hexulose-6-phosphate isomerase
VCA1552_03010	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
VCA1552_03011	COG0561	phosphatase activity
VCA1552_03017	COG3038	cytochrome b561
VCA1552_03018	COG0366	Alpha amylase catalytic
VCA1552_03023	COG0745	RESPONSE REGULATOR receiver
VCA1552_03024	COG5002	protein histidine kinase activity
VCA1552_03029	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VCA1552_03032	COG2814	Major facilitator Superfamily
VCA1552_03035	COG1686	Belongs to the peptidase S11 family
VCA1552_03039	COG1943	Transposase
VCA1552_03040	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCA1552_03040	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCA1552_03041	COG0509	glycine decarboxylation via glycine cleavage system
VCA1552_03042	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCA1552_03044	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VCA1552_03046	COG3039	Transposase
VCA1552_03051	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
VCA1552_03053	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VCA1552_03054	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
VCA1552_03061	COG1028	Short-chain dehydrogenase reductase Sdr
VCA1552_03064	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VCA1552_03069	COG0494	nUDIX hydrolase
VCA1552_03071	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCA1552_03072	COG3040	lipid binding
VCA1552_03076	COG3041	Addiction module toxin RelE StbE family
VCA1552_03085	COG1619	proteins homologs of microcin C7 resistance protein MccF
VCA1552_03093	COG0346	lactoylglutathione lyase activity
VCA1552_03096	COG3040	lipid binding
VCA1552_03098	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
VCA1552_03099	COG1280	lysine exporter protein (LysE YggA)
VCA1552_03126	COG3549	Plasmid maintenance system killer
VCA1552_03127	COG3093	addiction module antidote protein HigA
VCA1552_03128	COG0384	phenazine biosynthesis protein PhzF
VCA1552_03134	COG0346	lactoylglutathione lyase activity
VCA1552_03137	COG3040	lipid binding
VCA1552_03144	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCA1552_03158	COG1619	proteins homologs of microcin C7 resistance protein MccF
VCA1552_03162	COG3040	lipid binding
VCA1552_03173	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
VCA1552_03174	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
VCA1552_03175	COG4977	sequence-specific DNA binding
VCA1552_03186	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
VCA1552_03187	COG2944	sequence-specific DNA binding
VCA1552_03190	COG3039	Transposase
VCA1552_03191	COG0110	maltose O-acetyltransferase activity
VCA1552_03194	COG0346	lactoylglutathione lyase activity
VCA1552_03210	COG1943	Transposase
VCA1552_03220	COG0346	lactoylglutathione lyase activity
VCA1552_03225	COG1328	CTP reductase activity
VCA1552_03226	COG0602	queuosine metabolic process
VCA1552_03228	COG4067	protein conserved in archaea
VCA1552_03228	COG0189	ligase activity
VCA1552_03229	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCA1552_03229	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCA1552_03229	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VCA1552_03230	COG1105	Belongs to the carbohydrate kinase PfkB family
VCA1552_03231	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCA1552_03231	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCA1552_03232	COG1609	Transcriptional regulator
VCA1552_03233	COG0420	3'-5' exonuclease activity
VCA1552_03234	COG0419	ATPase involved in DNA repair
VCA1552_03235	COG2205	protein histidine kinase activity
VCA1552_03235	COG0784	Response regulator, receiver
VCA1552_03236	COG0156	8-amino-7-oxononanoate synthase activity
VCA1552_03238	COG0038	chloride channel
VCA1552_03239	COG0523	cobalamin synthesis protein
VCA1552_03241	COG3158	transport of potassium into the cell
VCA1552_03242	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
VCA1552_03242	COG0674	pyruvate-flavodoxin oxidoreductase activity
VCA1552_03242	COG1013	pyruvate-flavodoxin oxidoreductase activity
VCA1552_03242	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VCA1552_03243	COG2205	protein histidine kinase activity
VCA1552_03244	COG0745	RESPONSE REGULATOR receiver
VCA1552_03245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCA1552_03246	COG0586	Pfam SNARE associated Golgi protein
VCA1552_03248	COG2200	EAL domain
VCA1552_03250	COG3038	cytochrome b561
VCA1552_03252	COG2116	formate transmembrane transporter activity
VCA1552_03253	COG0583	DNA-binding transcription factor activity
VCA1552_03255	COG3593	DNA synthesis involved in DNA repair
VCA1552_03256	COG0737	Belongs to the 5'-nucleotidase family
VCA1552_03261	COG2824	Alkylphosphonate utilization operon protein PhnA
VCA1552_03271	COG3706	GGDEF domain
VCA1552_03274	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VCA1552_03275	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VCA1552_03277	COG0745	RESPONSE REGULATOR receiver
VCA1552_03281	COG0023	Translation Initiation Factor
VCA1552_03283	COG1181	Belongs to the D-alanine--D-alanine ligase family
VCA1552_03285	COG0045	succinate-CoA ligase (ADP-forming) activity
VCA1552_03285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCA1552_03285	COG1042	CoA-binding domain protein
VCA1552_03286	COG0583	DNA-binding transcription factor activity
VCA1552_03287	COG4771	TonB-dependent receptor
VCA1552_03287	COG1629	transport
VCA1552_03290	COG2050	protein possibly involved in aromatic compounds catabolism
VCA1552_03294	COG0625	glutathione transferase activity
VCA1552_03297	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VCA1552_03298	COG4172	Belongs to the ABC transporter superfamily
VCA1552_03299	COG4239	(ABC) transporter, permease
VCA1552_03300	COG4174	ABC transporter (Permease)
VCA1552_03301	COG4166	transmembrane transport
VCA1552_03310	COG3842	ATPase activity
VCA1552_03312	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCA1552_03314	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCA1552_03315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCA1552_03316	COG1011	Hydrolase
VCA1552_03318	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VCA1552_03319	COG1970	mechanosensitive ion channel activity
VCA1552_03320	COG2759	Belongs to the formate--tetrahydrofolate ligase family
VCA1552_03321	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCA1552_03321	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCA1552_03322	COG0302	gtp cyclohydrolase
VCA1552_03324	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCA1552_03326	COG2897	thiosulfate sulfurtransferase activity
VCA1552_03327	COG2390	Transcriptional regulator
VCA1552_03328	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
VCA1552_03329	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCA1552_03334	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCA1552_03339	COG0583	DNA-binding transcription factor activity
VCA1552_03340	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
VCA1552_03341	COG0778	Nitroreductase
VCA1552_03346	COG0640	Transcriptional regulator
VCA1552_03348	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCA1552_03357	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCA1552_03357	COG1263	PTS System
VCA1552_03359	COG1621	beta-fructofuranosidase activity
VCA1552_03360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCA1552_03361	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCA1552_03363	COG2885	chlorophyll binding
VCA1552_03364	COG0545	Peptidyl-prolyl cis-trans isomerase
VCA1552_03365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCA1552_03366	COG0840	transmembrane signaling receptor activity
VCA1552_03367	COG3069	C4-dicarboxylate transmembrane transporter activity
VCA1552_03368	COG1760	l-serine dehydratase
VCA1552_03373	COG1609	Transcriptional regulator
VCA1552_03374	COG2197	response regulator
VCA1552_03375	COG3850	Histidine kinase
VCA1552_03376	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCA1552_03378	COG0243	molybdopterin cofactor binding
VCA1552_03382	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCA1552_03383	COG2197	response regulator
VCA1552_03384	COG3851	Histidine kinase
VCA1552_03385	COG2271	Major facilitator Superfamily
VCA1552_03386	COG1840	ABC-type Fe3 transport system, periplasmic component
VCA1552_03388	COG3842	ATPase activity
VCA1552_03389	COG3243	poly(R)-hydroxyalkanoic acid synthase
VCA1552_03391	COG0183	Belongs to the thiolase family
VCA1552_03393	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCA1552_03394	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCA1552_03397	COG3706	GGDEF domain
VCA1552_03398	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCA1552_03400	COG1979	alcohol dehydrogenase
VCA1552_03403	COG4191	Histidine kinase
VCA1552_03404	COG1840	ABC-type Fe3 transport system, periplasmic component
VCA1552_03406	COG2271	Major facilitator Superfamily
VCA1552_03407	COG0469	pyruvate kinase activity
VCA1552_03408	COG0784	Response regulator, receiver
VCA1552_03408	COG2205	protein histidine kinase activity
VCA1552_03408	COG2198	Histidine kinase
VCA1552_03409	COG1879	ABC-type sugar transport system periplasmic component
VCA1552_03410	COG1803	Methylglyoxal synthase
VCA1552_03411	COG1335	isochorismatase
VCA1552_03412	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VCA1552_03415	COG0210	DNA helicase
VCA1552_03416	COG1289	transmembrane transporter activity
VCA1552_03422	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
VCA1552_03423	COG4149	molybdate abc transporter
VCA1552_03424	COG0725	ABC transporter, periplasmic molybdate-binding protein
VCA1552_03425	COG1492	cobalamin metabolic process
VCA1552_03433	COG5002	protein histidine kinase activity
VCA1552_03433	COG0784	Response regulator, receiver
VCA1552_03434	COG1879	ABC-type sugar transport system periplasmic component
VCA1552_03436	COG2827	Endonuclease containing a URI domain
VCA1552_03442	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
VCA1552_03443	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VCA1552_03444	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCA1552_03445	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
VCA1552_03446	COG0247	lactate metabolic process
VCA1552_03447	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCA1552_03448	COG3118	belongs to the thioredoxin family
VCA1552_03454	COG0583	DNA-binding transcription factor activity
VCA1552_03455	COG4160	amino acid transport
VCA1552_03456	COG4215	(ABC) transporter
VCA1552_03457	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCA1552_03458	COG1126	abc transporter atp-binding protein
VCA1552_03460	COG2425	protein containing a von Willebrand factor type A (vWA) domain
VCA1552_03462	COG0494	nUDIX hydrolase
VCA1552_03463	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VCA1552_03465	COG1309	transcriptional regulator
VCA1552_03466	COG0513	Belongs to the DEAD box helicase family
VCA1552_03467	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
VCA1552_03469	COG0814	amino acid
VCA1552_03470	COG0840	transmembrane signaling receptor activity
VCA1552_03471	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VCA1552_03472	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
VCA1552_03474	COG1984	allophanate hydrolase subunit 2
VCA1552_03477	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VCA1552_03478	COG4181	ATPase activity
VCA1552_03480	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCA1552_03481	COG5001	Diguanylate cyclase
VCA1552_03481	COG1716	ATPase activity
VCA1552_03483	COG0484	heat shock protein binding
VCA1552_03492	COG0546	phosphoglycolate phosphatase activity
VCA1552_03495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCA1552_03496	COG1368	sulfuric ester hydrolase activity
VCA1552_03498	COG0513	Belongs to the DEAD box helicase family
VCA1552_03499	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
VCA1552_03501	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCA1552_03503	COG3046	protein related to deoxyribodipyrimidine photolyase
VCA1552_03505	COG3397	chitin binding
VCA1552_03506	COG3227	Zinc metalloprotease (Elastase)
VCA1552_03508	COG0010	Belongs to the arginase family
VCA1552_03509	COG1166	arginine decarboxylase activity
VCA1552_03511	COG2239	Acts as a magnesium transporter
VCA1552_03512	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCA1552_03513	COG0459	protein refolding
VCA1552_03515	COG0527	aspartate kinase activity
VCA1552_03516	COG0662	Cupin 2, conserved barrel domain protein
VCA1552_03517	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VCA1552_03518	COG0456	acetyltransferase
VCA1552_03520	COG2154	pterin-4-alpha-carbinolamine dehydratase
VCA1552_03521	COG3186	Phenylalanine-4-hydroxylase
VCA1552_03522	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCA1552_03525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCA1552_03526	COG0583	DNA-binding transcription factor activity
VCA1552_03529	COG2171	N-acyltransferase activity
VCA1552_03530	COG1253	flavin adenine dinucleotide binding
VCA1552_03531	COG1765	OsmC-like protein
VCA1552_03537	COG0531	amino acid
VCA1552_03538	COG3706	GGDEF domain
VCA1552_03540	COG3279	Response regulator of the LytR AlgR family
VCA1552_03541	COG3275	phosphorelay sensor kinase activity
VCA1552_03544	COG1136	(ABC) transporter
VCA1552_03544	COG0577	efflux transmembrane transporter activity
VCA1552_03545	COG1136	(ABC) transporter
VCA1552_03547	COG4989	oxidoreductase activity
VCA1552_03548	COG0366	Alpha amylase catalytic
VCA1552_03549	COG2067	long-chain fatty acid transport protein
VCA1552_03550	COG2267	carboxylic ester hydrolase activity
VCA1552_03552	COG3227	Zinc metalloprotease (Elastase)
VCA1552_03553	COG3047	cAMP biosynthetic process
VCA1552_03555	COG1686	Belongs to the peptidase S11 family
VCA1552_03556	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VCA1552_03557	COG1271	oxidase subunit
VCA1552_03558	COG1294	oxidase, subunit
VCA1552_03561	COG3048	D-serine ammonia-lyase activity
VCA1552_03562	COG0583	DNA-binding transcription factor activity
VCA1552_03569	COG1063	alcohol dehydrogenase
VCA1552_03575	COG0346	lactoylglutathione lyase activity
VCA1552_03579	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
VCA1552_03580	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCA1552_03581	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VCA1552_03582	COG0363	glucosamine-6-phosphate deaminase activity
VCA1552_03583	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VCA1552_03588	COG1929	Belongs to the glycerate kinase type-1 family
VCA1552_03589	COG2610	gluconate transmembrane transporter activity
VCA1552_03590	COG3835	regulator
VCA1552_03592	COG0748	coenzyme F420 binding
VCA1552_03593	COG3721	Heme iron utilization protein
VCA1552_03595	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCA1552_03596	COG0811	peptide transport
VCA1552_03597	COG0848	biopolymer transport protein
VCA1552_03598	COG4558	Periplasmic binding protein
VCA1552_03599	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCA1552_03600	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VCA1552_03607	COG3217	Mosc domain protein beta barrel domain protein
VCA1552_03607	COG0633	Ferredoxin
VCA1552_03607	COG3217	Mosc domain protein beta barrel domain protein
VCA1552_03607	COG0633	Ferredoxin
VCA1552_03608	COG0418	dihydroorotase activity
VCA1552_03610	COG3152	Membrane
VCA1552_03612	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCA1552_03613	COG2354	Protein conserved in bacteria
VCA1552_03614	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCA1552_03616	COG1278	Cold shock
VCA1552_03621	COG3706	GGDEF domain
VCA1552_03622	COG1349	DNA-binding transcription factor activity
VCA1552_03626	COG3833	ABC-type maltose transport systems, permease component
VCA1552_03627	COG1175	transmembrane transport
VCA1552_03629	COG3842	ATPase activity
VCA1552_03630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCA1552_03633	COG0393	Putative heavy-metal-binding
VCA1552_03634	COG2197	response regulator
VCA1552_03635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCA1552_03636	COG0784	Response regulator, receiver
VCA1552_03636	COG0835	chemotaxis
VCA1552_03637	COG1846	Transcriptional regulator
VCA1552_03638	COG3706	GGDEF domain
VCA1552_03646	COG0583	DNA-binding transcription factor activity
VCA1552_03647	COG5001	Diguanylate cyclase
VCA1552_03649	COG1741	Belongs to the pirin family
VCA1552_03650	COG3123	guanosine phosphorylase activity
VCA1552_03652	COG2211	Major facilitator Superfamily
VCA1552_03654	COG0840	transmembrane signaling receptor activity
VCA1552_03655	COG1067	ATP-dependent peptidase activity
VCA1552_03657	COG4172	Belongs to the ABC transporter superfamily
VCA1552_03662	COG0583	DNA-binding transcription factor activity
VCA1552_03663	COG1620	l-lactate permease
VCA1552_03664	COG1304	FMN binding
VCA1552_03666	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
VCA1552_03668	COG0840	transmembrane signaling receptor activity
VCA1552_03670	COG0513	Belongs to the DEAD box helicase family
VCA1552_03671	COG0583	DNA-binding transcription factor activity
VCA1552_03673	COG1902	pentaerythritol trinitrate reductase activity
VCA1552_03675	COG1132	(ABC) transporter
VCA1552_03677	COG1902	pentaerythritol trinitrate reductase activity
VCA1552_03679	COG1280	lysine exporter protein (LysE YggA)
VCA1552_03680	COG2207	Transcriptional regulator
VCA1552_03684	COG1846	Transcriptional regulator
VCA1552_03685	COG1764	response to oxidative stress
VCA1552_03686	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCA1552_03687	COG0697	spore germination
VCA1552_03689	COG0700	Nucleoside recognition
VCA1552_03690	COG3366	ferrous iron transmembrane transporter activity
VCA1552_03691	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
VCA1552_03693	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VCA1552_03694	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
VCA1552_03695	COG2259	Doxx family
VCA1552_03700	COG0363	glucosamine-6-phosphate deaminase activity
VCA1552_03703	COG4580	involved in the transport of maltose and maltodextrins
VCA1552_03706	COG0840	transmembrane signaling receptor activity
VCA1552_03709	COG0840	transmembrane signaling receptor activity
VCA1552_03711	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCA1552_03712	COG1126	abc transporter atp-binding protein
VCA1552_03714	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCA1552_03715	COG4597	amino acid ABC transporter
VCA1552_03716	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCA1552_03717	COG0739	heme binding
VCA1552_03720	COG2213	PTS system mannitol-specific
VCA1552_03720	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCA1552_03721	COG0246	Mannitol dehydrogenase
VCA1552_03722	COG3722	fumarate hydratase activity
VCA1552_03723	COG0673	inositol 2-dehydrogenase activity
VCA1552_03729	COG2910	NAD(P)H-binding
VCA1552_03731	COG0840	transmembrane signaling receptor activity
VCA1552_03732	COG4221	oxidoreductase activity
VCA1552_03734	COG1901	pseudouridine methyltransferase
VCA1552_03735	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VCA1552_03737	COG0531	amino acid
VCA1552_03738	COG1982	Orn Lys Arg decarboxylase major
VCA1552_03743	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCA1552_03748	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VCA1552_03750	COG0259	pyridoxamine-phosphate oxidase activity
VCA1552_03756	COG0745	RESPONSE REGULATOR receiver
VCA1552_03760	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
VCA1552_03761	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCA1552_03762	COG0840	transmembrane signaling receptor activity
VCA1552_03763	COG0835	chemotaxis
VCA1552_03764	COG0835	chemotaxis
VCA1552_03765	COG0643	Histidine kinase
VCA1552_03765	COG2198	Histidine kinase
VCA1552_03769	COG0601	transmembrane transport
VCA1552_03770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCA1552_03772	COG2194	sulfuric ester hydrolase activity
VCA1552_03773	COG0642	Histidine kinase
VCA1552_03774	COG0745	RESPONSE REGULATOR receiver
VCA1552_03780	COG1444	tRNA N-acetyltransferase activity
VCA1552_03781	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine