locus-tag	class	description
GTF72_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GTF72_00010	COG0592	DNA-directed DNA polymerase activity
GTF72_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GTF72_00020	COG0187	DNA topoisomerase II activity
GTF72_00030	COG0071	Belongs to the small heat shock protein (HSP20) family
GTF72_00035	COG3977	Valine--pyruvate aminotransferase
GTF72_00040	COG0751	glycine-tRNA ligase activity
GTF72_00045	COG0752	glycyl-tRNA synthetase alpha subunit
GTF72_00050	COG2119	membrane
GTF72_00060	COG0425	Belongs to the sulfur carrier protein TusA family
GTF72_00070	COG0604	alcohol dehydrogenase
GTF72_00080	COG0129	dihydroxy-acid dehydratase activity
GTF72_00085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GTF72_00100	COG0606	chelatase, subunit chli
GTF72_00105	COG0204	Acyl-transferase
GTF72_00110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GTF72_00115	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GTF72_00125	COG3084	Protein conserved in bacteria
GTF72_00130	COG4326	sporulation control protein
GTF72_00135	COG1272	protein, Hemolysin III
GTF72_00145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GTF72_00150	COG0569	domain protein
GTF72_00155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GTF72_00155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GTF72_00160	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GTF72_00165	COG0242	peptide deformylase activity
GTF72_00170	COG1652	LysM domain
GTF72_00175	COG0758	DNA mediated transformation
GTF72_00180	COG2922	Belongs to the Smg family
GTF72_00185	COG0551	DNA topoisomerase type I activity
GTF72_00190	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GTF72_00195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GTF72_00200	COG0009	L-threonylcarbamoyladenylate synthase
GTF72_00205	COG0408	coproporphyrinogen oxidase activity
GTF72_00210	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GTF72_00220	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GTF72_00260	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GTF72_00265	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GTF72_00275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GTF72_00280	COG2104	thiamine diphosphate biosynthetic process
GTF72_00285	COG2022	thiamine diphosphate biosynthetic process
GTF72_00290	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GTF72_00295	COG0006	proline dipeptidase activity
GTF72_00295	COG0006	proline dipeptidase activity
GTF72_00315	COG1522	sequence-specific DNA binding
GTF72_00320	COG5002	protein histidine kinase activity
GTF72_00320	COG5001	Diguanylate cyclase
GTF72_00340	COG0589	response to stress
GTF72_00345	COG1528	Iron-storage protein
GTF72_00355	COG2081	HI0933 family
GTF72_00365	COG1322	Protein conserved in bacteria
GTF72_00370	COG2226	methyltransferase
GTF72_00385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GTF72_00390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GTF72_00395	COG0805	protein transport
GTF72_00400	COG1858	cytochrome C peroxidase
GTF72_00405	COG0534	Mate efflux family protein
GTF72_00415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GTF72_00425	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GTF72_00430	COG3161	chorismate lyase activity
GTF72_00435	COG1580	Controls the rotational direction of flagella during chemotaxis
GTF72_00440	COG0840	transmembrane signaling receptor activity
GTF72_00450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GTF72_00455	COG0084	hydrolase, TatD family'
GTF72_00470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GTF72_00470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GTF72_00490	COG3078	GTPase activator activity
GTF72_00505	COG3071	HemY protein
GTF72_00510	COG2959	enzyme of heme biosynthesis
GTF72_00515	COG1587	Uroporphyrinogen-III synthase
GTF72_00520	COG0181	hydroxymethylbilane synthase activity
GTF72_00530	COG1965	Belongs to the frataxin family
GTF72_00540	COG0019	diaminopimelate decarboxylase activity
GTF72_00545	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GTF72_00555	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GTF72_00560	COG1011	Hydrolase
GTF72_00565	COG2200	EAL domain
GTF72_00565	COG2199	diguanylate cyclase activity
GTF72_00565	COG3287	FIST C domain
GTF72_00580	COG0561	phosphatase activity
GTF72_00585	COG2267	carboxylic ester hydrolase activity
GTF72_00590	COG1280	lysine exporter protein (LysE YggA)
GTF72_00595	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GTF72_00600	COG0783	Belongs to the Dps family
GTF72_00630	COG0742	ribosomal rna small subunit methyltransferase
GTF72_00635	COG0552	protein localization to endoplasmic reticulum
GTF72_00640	COG2884	Cell division ATP-binding protein ftsE
GTF72_00645	COG2177	Part of the ABC transporter FtsEX involved in
GTF72_00650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GTF72_00655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GTF72_00670	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GTF72_00675	COG4206	TonB-dependent receptor
GTF72_00680	COG1404	Belongs to the peptidase S8 family
GTF72_00685	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GTF72_00755	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GTF72_00760	COG3300	MHYT domain
GTF72_00760	COG5001	Diguanylate cyclase
GTF72_00770	COG3852	Histidine kinase
GTF72_00780	COG0174	glutamine synthetase
GTF72_00800	COG1295	ribonuclease BN
GTF72_00805	COG1490	D-aminoacyl-tRNA deacylase activity
GTF72_00810	COG0456	acetyltransferase
GTF72_00820	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GTF72_00825	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GTF72_00830	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GTF72_00835	COG3031	protein transport across the cell outer membrane
GTF72_00845	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GTF72_00850	COG1459	type II secretion system
GTF72_00855	COG2165	general secretion pathway protein
GTF72_00860	COG2165	general secretion pathway protein
GTF72_00865	COG2165	general secretion pathway protein
GTF72_00870	COG4795	General secretion pathway protein
GTF72_00875	COG3156	type II secretion system protein K
GTF72_00880	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GTF72_00885	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GTF72_00895	COG1218	3'(2'),5'-bisphosphate nucleotidase
GTF72_00900	COG0494	nUDIX hydrolase
GTF72_00910	COG1040	competence protein
GTF72_00920	COG0596	Alpha beta hydrolase
GTF72_00930	COG2183	response to ionizing radiation
GTF72_00935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GTF72_00940	COG0745	RESPONSE REGULATOR receiver
GTF72_00950	COG2233	PERMEase
GTF72_00955	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GTF72_00960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GTF72_00965	COG1758	RNA polymerase activity
GTF72_00970	COG0194	GDP metabolic process
GTF72_00975	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GTF72_00980	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GTF72_01000	COG4232	protein-disulfide reductase activity
GTF72_01010	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GTF72_01015	COG1027	Aspartate ammonia-lyase
GTF72_01020	COG3706	GGDEF domain
GTF72_01025	COG3030	protein affecting phage T7 exclusion by the F plasmid
GTF72_01030	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GTF72_01040	COG2205	protein histidine kinase activity
GTF72_01045	COG0745	RESPONSE REGULATOR receiver
GTF72_01055	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GTF72_01060	COG0205	6-phosphofructokinase activity
GTF72_01065	COG1494	fructose-1,6-bisphosphatase
GTF72_01070	COG3074	FtsZ-dependent cytokinesis
GTF72_01075	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GTF72_01080	COG0460	homoserine dehydrogenase
GTF72_01080	COG0527	aspartate kinase activity
GTF72_01085	COG0626	cystathionine gamma-synthase activity
GTF72_01090	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
GTF72_01095	COG0281	malic enzyme
GTF72_01100	COG0254	rRNA binding
GTF72_01105	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GTF72_01110	COG1609	Transcriptional regulator
GTF72_01115	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GTF72_01120	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GTF72_01125	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GTF72_01130	COG1575	Belongs to the MenA family. Type 1 subfamily
GTF72_01135	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GTF72_01140	COG0534	Mate efflux family protein
GTF72_01145	COG0149	triose-phosphate isomerase activity
GTF72_01170	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GTF72_01175	COG0459	protein refolding
GTF72_01185	COG1509	lysine 2,3-aminomutase activity
GTF72_01190	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GTF72_01200	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GTF72_01205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GTF72_01210	COG1053	succinate dehydrogenase
GTF72_01215	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GTF72_01220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GTF72_01225	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GTF72_01230	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GTF72_01235	COG1045	serine acetyltransferase
GTF72_01245	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GTF72_01250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GTF72_01255	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GTF72_01260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GTF72_01265	COG0137	argininosuccinate synthase activity
GTF72_01270	COG0165	Argininosuccinate lyase
GTF72_01280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GTF72_01285	COG0678	peroxiredoxin activity
GTF72_01285	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GTF72_01295	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GTF72_01325	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GTF72_01330	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GTF72_01340	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GTF72_01345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GTF72_01350	COG0546	phosphoglycolate phosphatase activity
GTF72_01355	COG0180	Tryptophanyl-tRNA synthetase
GTF72_01370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GTF72_01380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GTF72_01390	COG1012	belongs to the aldehyde dehydrogenase family
GTF72_01405	COG3954	Phosphoribulokinase
GTF72_01415	COG0429	hydrolase of the alpha beta-hydrolase fold
GTF72_01425	COG0488	(ABC) transporter
GTF72_01430	COG2249	NAD(P)H dehydrogenase (quinone) activity
GTF72_01445	COG1047	Peptidyl-prolyl cis-trans
GTF72_01460	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GTF72_01465	COG3083	sulfuric ester hydrolase activity
GTF72_01470	COG0557	exoribonuclease II activity
GTF72_01475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GTF72_01480	COG0051	transcription antitermination factor activity, RNA binding
GTF72_01485	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GTF72_01490	COG0088	Forms part of the polypeptide exit tunnel
GTF72_01495	COG0089	rRNA binding
GTF72_01500	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GTF72_01505	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GTF72_01510	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GTF72_01515	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GTF72_01520	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GTF72_01525	COG0255	Belongs to the universal ribosomal protein uL29 family
GTF72_01530	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GTF72_01535	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GTF72_01540	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GTF72_01545	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GTF72_01550	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GTF72_01555	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GTF72_01565	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GTF72_01570	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GTF72_01575	COG1841	ribosomal large subunit assembly
GTF72_01585	COG0201	protein transport
GTF72_01590	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GTF72_01595	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GTF72_01600	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GTF72_01605	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GTF72_01610	COG0202	RNA polymerase activity
GTF72_01615	COG0203	ribosomal protein L17
GTF72_01625	COG0545	Peptidyl-prolyl cis-trans isomerase
GTF72_01630	COG3266	domain, Protein
GTF72_01630	COG3061	Opacity-associated protein A
GTF72_01635	COG0697	spore germination
GTF72_01640	COG2153	protein acetylation
GTF72_01645	COG0513	Belongs to the DEAD box helicase family
GTF72_01655	COG0737	Belongs to the 5'-nucleotidase family
GTF72_01660	COG1648	precorrin-2 dehydrogenase activity
GTF72_01660	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GTF72_01675	COG0529	Catalyzes the synthesis of activated sulfate
GTF72_01695	COG1136	(ABC) transporter
GTF72_01710	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GTF72_01715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GTF72_01720	COG0729	surface antigen
GTF72_01730	COG2105	PFAM AIG2 family protein
GTF72_01735	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GTF72_01745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GTF72_01750	COG0163	prenyltransferase activity
GTF72_01760	COG1178	ABC-type Fe3 transport system permease component
GTF72_01765	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GTF72_01770	COG3028	Belongs to the UPF0307 family
GTF72_01775	COG0312	modulator of DNA gyrase
GTF72_01780	COG2239	Acts as a magnesium transporter
GTF72_01785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTF72_01790	COG1660	Displays ATPase and GTPase activities
GTF72_01795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTF72_01800	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GTF72_01810	COG1137	ATPase activity
GTF72_01815	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GTF72_01830	COG0517	IMP dehydrogenase activity
GTF72_01830	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GTF72_01840	COG1127	ABC transporter
GTF72_01845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GTF72_01850	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GTF72_01855	COG2854	intermembrane phospholipid transfer
GTF72_01865	COG5007	Belongs to the BolA IbaG family
GTF72_01870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GTF72_01880	COG0251	oxidation-reduction process
GTF72_01890	COG0540	Belongs to the ATCase OTCase family
GTF72_01900	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GTF72_01910	COG0564	pseudouridine synthase activity
GTF72_01915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GTF72_01920	COG0525	valine-tRNA ligase activity
GTF72_01925	COG2927	DNA polymerase III (CHI subunit)
GTF72_01930	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GTF72_01935	COG0795	lipopolysaccharide-transporting ATPase activity
GTF72_01940	COG0795	lipopolysaccharide-transporting ATPase activity
GTF72_01955	COG3437	response regulator, receiver
GTF72_02000	COG0066	3-isopropylmalate dehydratase activity
GTF72_02005	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GTF72_02010	COG0473	3-isopropylmalate dehydrogenase activity
GTF72_02035	COG0583	DNA-binding transcription factor activity
GTF72_02040	COG1022	Amp-dependent synthetase and ligase
GTF72_02045	COG0028	Belongs to the TPP enzyme family
GTF72_02050	COG0440	acetolactate synthase activity
GTF72_02055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GTF72_02060	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GTF72_02065	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GTF72_02075	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GTF72_02080	COG3079	Belongs to the UPF0149 family
GTF72_02085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTF72_02090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTF72_02105	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GTF72_02115	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GTF72_02120	COG1595	DNA-templated transcription, initiation
GTF72_02135	COG3086	response to oxidative stress
GTF72_02140	COG0481	GTPase activity
GTF72_02155	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GTF72_02160	COG1381	Involved in DNA repair and RecF pathway recombination
GTF72_02165	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GTF72_02185	COG5001	Diguanylate cyclase
GTF72_02200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GTF72_02205	COG3956	TIGRFAM MazG family protein
GTF72_02210	COG0504	CTP synthase activity
GTF72_02215	COG0148	phosphopyruvate hydratase activity
GTF72_02225	COG3409	Peptidoglycan-binding domain 1 protein
GTF72_02225	COG3267	Type II secretory pathway component ExeA
GTF72_02235	COG4991	sh3 domain protein
GTF72_02240	COG0306	phosphate transporter
GTF72_02245	COG1392	Phosphate transport regulator
GTF72_02250	COG3025	triphosphatase activity
GTF72_02255	COG0840	transmembrane signaling receptor activity
GTF72_02260	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GTF72_02270	COG1538	Outer membrane efflux protein
GTF72_02275	COG0494	nUDIX hydrolase
GTF72_02280	COG3151	Protein conserved in bacteria
GTF72_02290	COG3150	esterase
GTF72_02295	COG0187	DNA topoisomerase II activity
GTF72_02300	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GTF72_02310	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GTF72_02315	COG0237	dephospho-CoA kinase activity
GTF72_02325	COG1459	type II secretion system
GTF72_02330	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GTF72_02350	COG0716	FMN binding
GTF72_02355	COG4974	Belongs to the 'phage' integrase family
GTF72_02360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GTF72_02365	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GTF72_02370	COG0737	Belongs to the 5'-nucleotidase family
GTF72_02375	COG2186	Transcriptional regulator
GTF72_02380	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GTF72_02385	COG0508	dehydrogenase complex catalyzes the overall conversion of
GTF72_02390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GTF72_02405	COG3116	cell division
GTF72_02410	COG0768	penicillin binding
GTF72_02415	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GTF72_02420	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GTF72_02430	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GTF72_02435	COG0772	Belongs to the SEDS family
GTF72_02445	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GTF72_02450	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GTF72_02455	COG0849	cell division
GTF72_02460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GTF72_02465	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GTF72_02475	COG0653	protein targeting
GTF72_02480	COG0494	nUDIX hydrolase
GTF72_02485	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GTF72_02495	COG0505	Belongs to the CarA family
GTF72_02500	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GTF72_02525	COG0730	response to heat
GTF72_02530	COG0583	DNA-binding transcription factor activity
GTF72_02535	COG2860	membrane
GTF72_02540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GTF72_02550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GTF72_02560	COG0493	'glutamate synthase
GTF72_02565	COG0069	glutamate synthase activity
GTF72_02565	COG0070	glutamate synthase
GTF72_02565	COG0067	glutamate synthase
GTF72_02575	COG0067	glutamate synthase
GTF72_02575	COG0070	glutamate synthase
GTF72_02575	COG0069	glutamate synthase activity
GTF72_02580	COG1242	4 iron, 4 sulfur cluster binding
GTF72_02585	COG4251	negative regulation of phosphorylation
GTF72_02585	COG2203	Gaf domain
GTF72_02585	COG5001	Diguanylate cyclase
GTF72_02585	COG3706	GGDEF domain
GTF72_02590	COG2198	Histidine kinase
GTF72_02590	COG5002	protein histidine kinase activity
GTF72_02590	COG0784	Response regulator, receiver
GTF72_02595	COG0745	RESPONSE REGULATOR receiver
GTF72_02605	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GTF72_02630	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GTF72_02635	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
GTF72_02640	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GTF72_02645	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GTF72_02660	COG1115	amino acid carrier protein
GTF72_02665	COG3022	response to hydroperoxide
GTF72_02675	COG0084	hydrolase, TatD family'
GTF72_02680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GTF72_02690	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GTF72_02695	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GTF72_02700	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GTF72_02705	COG0813	purine-nucleoside phosphorylase activity
GTF72_02715	COG0560	Phosphoserine phosphatase
GTF72_02725	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GTF72_02730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GTF72_02735	COG1022	Amp-dependent synthetase and ligase
GTF72_02750	COG3250	beta-galactosidase activity
GTF72_02755	COG1609	Transcriptional regulator
GTF72_02760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GTF72_02775	COG0189	ligase activity
GTF72_02775	COG0569	domain protein
GTF72_02780	COG0456	acetyltransferase
GTF72_02790	COG2171	N-acyltransferase activity
GTF72_02795	COG3141	response to X-ray
GTF72_02810	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GTF72_02815	COG1074	ATP-dependent DNA helicase activity
GTF72_02820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GTF72_02830	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GTF72_02830	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GTF72_02840	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GTF72_02845	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GTF72_02850	COG2166	iron-sulfur cluster assembly
GTF72_02855	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GTF72_02860	COG0693	protein deglycase activity
GTF72_02865	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GTF72_02870	COG3248	Nucleoside-binding outer membrane protein
GTF72_02880	COG1595	DNA-templated transcription, initiation
GTF72_02890	COG2211	Major facilitator Superfamily
GTF72_02895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GTF72_02905	COG2813	Specifically methylates the guanine in position
GTF72_02910	COG0271	Belongs to the BolA IbaG family
GTF72_02915	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GTF72_02920	COG1805	sodium ion transport
GTF72_02925	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GTF72_02930	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GTF72_02935	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GTF72_02940	COG2871	sodium ion transport
GTF72_02945	COG1477	protein flavinylation
GTF72_02965	COG3706	GGDEF domain
GTF72_02970	COG0733	neurotransmitter:sodium symporter activity
GTF72_02980	COG0189	ligase activity
GTF72_02985	COG0189	ligase activity
GTF72_02985	COG4067	protein conserved in archaea
GTF72_02995	COG2252	PERMEase
GTF72_03000	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GTF72_03015	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GTF72_03020	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GTF72_03025	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GTF72_03030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GTF72_03030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GTF72_03045	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GTF72_03050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GTF72_03055	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GTF72_03060	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GTF72_03070	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GTF72_03075	COG0024	Methionine aminopeptidase
GTF72_03080	COG0052	Belongs to the universal ribosomal protein uS2 family
GTF72_03085	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GTF72_03090	COG0528	UMP kinase activity
GTF72_03095	COG0233	cytoplasmic translational termination
GTF72_03100	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GTF72_03105	COG0575	Belongs to the CDS family
GTF72_03110	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GTF72_03115	COG0750	zinc metalloprotease
GTF72_03125	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GTF72_03130	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GTF72_03135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GTF72_03140	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GTF72_03145	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GTF72_03150	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GTF72_03155	COG0587	DNA-directed DNA polymerase activity
GTF72_03160	COG0825	malonyl-CoA metabolic process
GTF72_03165	COG0037	tRNA processing
GTF72_03175	COG3479	Phenolic acid decarboxylase
GTF72_03180	COG0347	Belongs to the P(II) protein family
GTF72_03185	COG3021	interspecies interaction between organisms
GTF72_03190	COG0741	lytic transglycosylase activity
GTF72_03190	COG1388	LysM domain
GTF72_03195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GTF72_03200	COG2226	methyltransferase
GTF72_03205	COG0328	RNA-DNA hybrid ribonuclease activity
GTF72_03220	COG1960	acyl-CoA dehydrogenase activity
GTF72_03225	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GTF72_03230	COG0121	glutamine amidotransferase
GTF72_03235	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GTF72_03240	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GTF72_03245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GTF72_03250	COG3706	GGDEF domain
GTF72_03255	COG1187	pseudouridine synthase activity
GTF72_03260	COG2840	Smr protein MutS2
GTF72_03275	COG3735	TraB family
GTF72_03290	COG2608	mercury ion transmembrane transporter activity
GTF72_03290	COG2217	Heavy metal translocating P-type atpase
GTF72_03295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GTF72_03310	COG1629	transport
GTF72_03310	COG4774	siderophore transport
GTF72_03315	COG2375	cellular response to nickel ion
GTF72_03320	COG2226	methyltransferase
GTF72_03320	COG3433	isochorismatase activity
GTF72_03320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GTF72_03355	COG0835	chemotaxis
GTF72_03355	COG0784	Response regulator, receiver
GTF72_03360	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GTF72_03365	COG1815	bacterial-type flagellum-dependent cell motility
GTF72_03380	COG1749	Flagellar hook protein flgE
GTF72_03385	COG4787	bacterial-type flagellum-dependent cell motility
GTF72_03395	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GTF72_03400	COG1706	bacterial-type flagellum-dependent cell motility
GTF72_03405	COG1705	Flagellar rod assembly protein muramidase FlgJ
GTF72_03405	COG3951	Flagellar rod assembly protein muramidase FlgJ
GTF72_03420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GTF72_03425	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GTF72_03510	COG0012	GTP binding
GTF72_03515	COG0193	aminoacyl-tRNA hydrolase activity
GTF72_03520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GTF72_03525	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GTF72_03530	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GTF72_03535	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GTF72_03540	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GTF72_03545	COG2890	protein-(glutamine-N5) methyltransferase activity
GTF72_03555	COG2912	Transglutaminase-like superfamily
GTF72_03560	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GTF72_03565	COG0737	Belongs to the 5'-nucleotidase family
GTF72_03570	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GTF72_03575	COG2233	PERMEase
GTF72_03595	COG1393	Belongs to the ArsC family
GTF72_03600	COG4783	chaperone-mediated protein folding
GTF72_03620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GTF72_03635	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GTF72_03645	COG1876	peptidase activity
GTF72_03655	COG1393	Belongs to the ArsC family
GTF72_03675	COG2837	iron assimilation
GTF72_03680	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GTF72_03685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GTF72_03690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GTF72_03695	COG1334	flagellar protein FlaG
GTF72_03700	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GTF72_03710	COG1516	flagellar protein fliS
GTF72_03720	COG4191	Histidine kinase
GTF72_03730	COG1677	Flagellar hook-basal body complex protein FliE
GTF72_03740	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GTF72_03745	COG1317	bacterial-type flagellum organization
GTF72_03770	COG1580	Controls the rotational direction of flagella during chemotaxis
GTF72_03795	COG1987	bacterial-type flagellum assembly
GTF72_03800	COG1684	flagellar biosynthetic protein fliR
GTF72_03810	COG2840	Smr protein MutS2
GTF72_03815	COG2890	protein-(glutamine-N5) methyltransferase activity
GTF72_03825	COG2860	membrane
GTF72_03830	COG3101	peptidyl-lysine hydroxylation
GTF72_03840	COG0431	NADPH-dependent FMN reductase
GTF72_03850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GTF72_03855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GTF72_03860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GTF72_03865	COG0735	belongs to the Fur family
GTF72_03875	COG0583	DNA-binding transcription factor activity
GTF72_03885	COG1346	cytolysis
GTF72_03900	COG0596	Alpha beta hydrolase
GTF72_03905	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GTF72_03910	COG0033	Phosphoglucomutase
GTF72_03920	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GTF72_03925	COG0372	Belongs to the citrate synthase family
GTF72_03930	COG2009	succinate dehydrogenase
GTF72_03935	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GTF72_03940	COG1053	succinate dehydrogenase
GTF72_03950	COG0567	Dehydrogenase, E1 component
GTF72_03955	COG0508	dehydrogenase complex catalyzes the overall conversion of
GTF72_03985	COG4977	sequence-specific DNA binding
GTF72_03990	COG1918	ferrous iron import across plasma membrane
GTF72_04010	COG0018	arginyl-trna synthetase
GTF72_04020	COG1025	Belongs to the peptidase M16 family
GTF72_04025	COG2062	phosphohistidine phosphatase, SixA
GTF72_04055	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GTF72_04060	COG0784	Response regulator, receiver
GTF72_04060	COG0643	Histidine kinase
GTF72_04060	COG2198	Histidine kinase
GTF72_04065	COG2201	protein-glutamate methylesterase activity
GTF72_04070	COG1192	Involved in chromosome partitioning
GTF72_04080	COG0835	chemotaxis
GTF72_04090	COG4133	protoheme IX ABC transporter activity
GTF72_04095	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GTF72_04100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GTF72_04110	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GTF72_04115	COG1138	Cytochrome C-type biogenesis protein
GTF72_04120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GTF72_04125	COG3088	subunit of a heme lyase
GTF72_04125	COG4235	cytochrome complex assembly
GTF72_04135	COG2853	Lipoprotein
GTF72_04155	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GTF72_04160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GTF72_04165	COG0123	including yeast histone deacetylase and acetoin utilization protein
GTF72_04180	COG3083	sulfuric ester hydrolase activity
GTF72_04185	COG3082	Protein of unknown function (DUF1414)
GTF72_04190	COG3081	Nucleoid-associated protein
GTF72_04200	COG1757	Na H antiporter
GTF72_04205	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GTF72_04210	COG2095	MarC family integral membrane protein
GTF72_04215	COG1012	belongs to the aldehyde dehydrogenase family
GTF72_04215	COG1454	alcohol dehydrogenase
GTF72_04225	COG0659	secondary active sulfate transmembrane transporter activity
GTF72_04230	COG1530	ribonuclease E activity
GTF72_04235	COG0564	pseudouridine synthase activity
GTF72_04240	COG0424	maF-like protein
GTF72_04245	COG1399	metal-binding, possibly nucleic acid-binding protein
GTF72_04250	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GTF72_04255	COG0416	fatty acid biosynthetic process
GTF72_04260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GTF72_04270	COG1028	Short-chain dehydrogenase reductase Sdr
GTF72_04275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GTF72_04280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GTF72_04285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GTF72_04290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GTF72_04295	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GTF72_04305	COG0084	hydrolase, TatD family'
GTF72_04310	COG1263	PTS System
GTF72_04310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTF72_04320	COG0733	neurotransmitter:sodium symporter activity
GTF72_04335	COG4667	esterase of the alpha-beta hydrolase superfamily
GTF72_04345	COG1940	carbohydrate kinase activity
GTF72_04350	COG0835	chemotaxis
GTF72_04350	COG0784	Response regulator, receiver
GTF72_04365	COG2226	methyltransferase
GTF72_04375	COG0676	glucose-6-phosphate 1-epimerase activity
GTF72_04380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GTF72_04385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GTF72_04395	COG3139	Protein of unknown function (DUF1315)
GTF72_04400	COG0252	asparaginase activity
GTF72_04405	COG0616	signal peptide processing
GTF72_04410	COG1902	pentaerythritol trinitrate reductase activity
GTF72_04410	COG0446	pyridine nucleotide-disulphide oxidoreductase
GTF72_04415	COG0788	formyltetrahydrofolate deformylase activity
GTF72_04425	COG1199	ATP-dependent helicase activity
GTF72_04430	COG1214	PFAM Peptidase M22, glycoprotease
GTF72_04445	COG0596	Alpha beta hydrolase
GTF72_04450	COG0318	PFAM AMP-dependent synthetase and ligase
GTF72_04455	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GTF72_04475	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GTF72_04485	COG0436	Aminotransferase
GTF72_04490	COG1169	isochorismate synthase
GTF72_04495	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GTF72_04500	COG0596	Alpha beta hydrolase
GTF72_04520	COG3135	benzoate transporter
GTF72_04525	COG1396	sequence-specific DNA binding
GTF72_04530	COG0840	transmembrane signaling receptor activity
GTF72_04540	COG0477	Major facilitator Superfamily
GTF72_04560	COG3015	lipoprotein NlpE involved in copper resistance
GTF72_04565	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GTF72_04570	COG2894	cell division
GTF72_04575	COG0850	regulation of cytokinetic process
GTF72_04580	COG3100	YcgL domain-containing protein
GTF72_04585	COG2951	lytic endotransglycosylase activity
GTF72_04595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GTF72_04600	COG3325	Belongs to the glycosyl hydrolase 18 family
GTF72_04600	COG3469	chitinase activity
GTF72_04605	COG3005	denitrification pathway
GTF72_04610	COG0243	molybdopterin cofactor binding
GTF72_04625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTF72_04635	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GTF72_04670	COG4589	Belongs to the CDS family
GTF72_04680	COG3300	MHYT domain
GTF72_04680	COG5001	Diguanylate cyclase
GTF72_04690	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GTF72_04695	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GTF72_04700	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GTF72_04705	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GTF72_04715	COG4191	Histidine kinase
GTF72_04725	COG0544	peptidyl-prolyl cis-trans isomerase activity
GTF72_04735	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GTF72_04740	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GTF72_04745	COG0776	regulation of translation
GTF72_04750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GTF72_04755	COG1555	photosystem II stabilization
GTF72_04760	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GTF72_04765	COG0539	negative regulation of cytoplasmic translation
GTF72_04770	COG0776	regulation of translation
GTF72_04775	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GTF72_04780	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GTF72_04800	COG0583	DNA-binding transcription factor activity
GTF72_04810	COG0686	Belongs to the AlaDH PNT family
GTF72_04820	COG1674	ftsk spoiiie
GTF72_04825	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GTF72_04830	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GTF72_04835	COG2186	Transcriptional regulator
GTF72_04850	COG0537	adenosine 5'-monophosphoramidase activity
GTF72_04875	COG3150	esterase
GTF72_04880	COG1252	NADH dehydrogenase
GTF72_04900	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GTF72_04910	COG4591	ABC-type transport system involved in lipoprotein release permease component
GTF72_04915	COG1136	(ABC) transporter
GTF72_04920	COG4591	ABC-type transport system involved in lipoprotein release permease component
GTF72_04930	COG0658	competence protein
GTF72_04930	COG2333	competence protein COMEC
GTF72_04935	COG1132	(ABC) transporter
GTF72_04940	COG1663	tetraacyldisaccharide 4'-kinase activity
GTF72_04945	COG2835	tetraacyldisaccharide 4'-kinase activity
GTF72_04950	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GTF72_04955	COG2719	SpoVR family
GTF72_04960	COG2718	Belongs to the UPF0229 family
GTF72_04965	COG2766	serine protein kinase
GTF72_04970	COG3013	Belongs to the UPF0304 family
GTF72_04980	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GTF72_04985	COG0840	transmembrane signaling receptor activity
GTF72_04995	COG1882	Formate acetyltransferase
GTF72_05020	COG4160	amino acid transport
GTF72_05025	COG0708	Exodeoxyribonuclease III
GTF72_05030	COG0840	transmembrane signaling receptor activity
GTF72_05040	COG3923	Primosomal replication protein n
GTF72_05045	COG0730	response to heat
GTF72_05050	COG1199	ATP-dependent helicase activity
GTF72_05055	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GTF72_05060	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GTF72_05065	COG3012	SEC-C Motif Domain Protein
GTF72_05070	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GTF72_05075	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GTF72_05080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GTF72_05085	COG0215	cysteine-tRNA ligase activity
GTF72_05090	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GTF72_05095	COG0632	four-way junction helicase activity
GTF72_05105	COG1271	oxidase subunit
GTF72_05110	COG1294	oxidase, subunit
GTF72_05115	COG4890	Cyd operon protein YbgT
GTF72_05120	COG3790	cyd operon protein YbgE
GTF72_05125	COG0824	Thioesterase
GTF72_05130	COG0811	peptide transport
GTF72_05145	COG0823	Involved in the tonB-independent uptake of proteins
GTF72_05150	COG2885	chlorophyll binding
GTF72_05160	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GTF72_05170	COG0784	Response regulator, receiver
GTF72_05170	COG5002	protein histidine kinase activity
GTF72_05180	COG1482	cell wall glycoprotein biosynthetic process
GTF72_05185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTF72_05185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTF72_05185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTF72_05190	COG2207	Transcriptional regulator
GTF72_05200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTF72_05205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTF72_05210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTF72_05220	COG1012	belongs to the aldehyde dehydrogenase family
GTF72_05225	COG3284	Transcriptional regulator
GTF72_05230	COG4628	conserved protein (DUF2132)
GTF72_05240	COG0415	Belongs to the DNA photolyase family
GTF72_05320	COG0488	(ABC) transporter
GTF72_05360	COG3941	tape measure
GTF72_05380	COG2003	Belongs to the UPF0758 family
GTF72_05390	COG4409	exo-alpha-(2->6)-sialidase activity
GTF72_05395	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GTF72_05400	COG1940	carbohydrate kinase activity
GTF72_05410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GTF72_05415	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GTF72_05420	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GTF72_05425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GTF72_05430	COG1737	Transcriptional regulator
GTF72_05435	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
GTF72_05440	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
GTF72_05460	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GTF72_05480	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GTF72_05500	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GTF72_05505	COG0582	viral genome integration into host DNA
GTF72_05510	COG0582	viral genome integration into host DNA
GTF72_05525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTF72_05535	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GTF72_05535	COG3008	intermembrane lipid transfer
GTF72_05540	COG2995	paraquat-inducible protein a
GTF72_05545	COG0668	transmembrane transport
GTF72_05565	COG1309	transcriptional regulator
GTF72_05570	COG1012	belongs to the aldehyde dehydrogenase family
GTF72_05600	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GTF72_05605	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GTF72_05630	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GTF72_05635	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GTF72_05640	COG0297	glycogen (starch) synthase activity
GTF72_05660	COG3070	regulator of competence-specific genes
GTF72_05665	COG1609	Transcriptional regulator
GTF72_05670	COG3381	protein complex oligomerization
GTF72_05675	COG0745	RESPONSE REGULATOR receiver
GTF72_05680	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GTF72_05685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GTF72_05695	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GTF72_05715	COG1032	radical SAM domain protein
GTF72_05720	COG5001	Diguanylate cyclase
GTF72_05725	COG0612	Peptidase, M16
GTF72_05740	COG0583	DNA-binding transcription factor activity
GTF72_05745	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GTF72_05755	COG2350	Protein conserved in bacteria
GTF72_05760	COG1607	acyl-coa hydrolase
GTF72_05775	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GTF72_05780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GTF72_05790	COG2116	formate transmembrane transporter activity
GTF72_05800	COG4459	periplasmic nitrate reductase
GTF72_05805	COG3005	denitrification pathway
GTF72_05810	COG0243	molybdopterin cofactor binding
GTF72_05830	COG1227	inorganic diphosphatase activity
GTF72_05845	COG4172	Belongs to the ABC transporter superfamily
GTF72_05860	COG4168	peptide transport system, permease
GTF72_05870	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GTF72_05875	COG1842	Phage shock protein A
GTF72_05890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTF72_05905	COG2818	Glycosylase
GTF72_05910	COG0626	cystathionine gamma-synthase activity
GTF72_05920	COG0733	neurotransmitter:sodium symporter activity
GTF72_05925	COG0564	pseudouridine synthase activity
GTF72_05930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GTF72_05935	COG4136	ATPase activity
GTF72_05940	COG4135	transport system, permease component
GTF72_05945	COG4134	Bacterial extracellular solute-binding protein
GTF72_05955	COG3313	Fe-S protein
GTF72_05965	COG0842	Transport permease protein
GTF72_05970	COG1131	(ABC) transporter
GTF72_05975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTF72_05980	COG0814	amino acid
GTF72_05990	COG2239	Acts as a magnesium transporter
GTF72_05995	COG0784	Response regulator, receiver
GTF72_05995	COG2205	protein histidine kinase activity
GTF72_06010	COG4934	collagen metabolic process
GTF72_06040	COG0840	transmembrane signaling receptor activity
GTF72_06050	COG2203	Gaf domain
GTF72_06050	COG3706	GGDEF domain
GTF72_06050	COG4251	negative regulation of phosphorylation
GTF72_06050	COG5001	Diguanylate cyclase
GTF72_06055	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GTF72_06075	COG1061	Type III restriction enzyme res subunit
GTF72_06080	COG1187	pseudouridine synthase activity
GTF72_06085	COG2814	Major facilitator Superfamily
GTF72_06095	COG0702	epimerase
GTF72_06100	COG0534	Mate efflux family protein
GTF72_06105	COG4181	ATPase activity
GTF72_06120	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GTF72_06130	COG1748	Saccharopine dehydrogenase
GTF72_06145	COG1538	Outer membrane efflux protein
GTF72_06165	COG0583	DNA-binding transcription factor activity
GTF72_06175	COG1451	nucleotide metabolic process
GTF72_06190	COG3063	Type IV pilus biogenesis stability protein PilW
GTF72_06195	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GTF72_06215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTF72_06230	COG3290	protein histidine kinase activity
GTF72_06235	COG4565	transcriptional regulatory protein
GTF72_06245	COG0835	chemotaxis
GTF72_06245	COG0784	Response regulator, receiver
GTF72_06290	COG1085	galactose-1-phosphate uridylyltransferase
GTF72_06295	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GTF72_06300	COG2017	converts alpha-aldose to the beta-anomer
GTF72_06305	COG3706	GGDEF domain
GTF72_06310	COG2200	EAL domain
GTF72_06310	COG2199	diguanylate cyclase activity
GTF72_06325	COG3527	Alpha-acetolactate decarboxylase
GTF72_06340	COG0753	catalase activity
GTF72_06360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GTF72_06370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GTF72_06410	COG1271	oxidase subunit
GTF72_06415	COG1294	oxidase, subunit
GTF72_06420	COG1136	(ABC) transporter
GTF72_06420	COG4591	ABC-type transport system involved in lipoprotein release permease component
GTF72_06425	COG1136	(ABC) transporter
GTF72_06425	COG0577	efflux transmembrane transporter activity
GTF72_06430	COG1136	(ABC) transporter
GTF72_06430	COG0577	efflux transmembrane transporter activity
GTF72_06450	COG0583	DNA-binding transcription factor activity
GTF72_06460	COG2723	6-phospho-beta-galactosidase activity
GTF72_06465	COG1609	Transcriptional regulator
GTF72_06470	COG0251	oxidation-reduction process
GTF72_06475	COG2731	YhcH YjgK YiaL family protein
GTF72_06480	COG0584	glycerophosphoryl diester phosphodiesterase
GTF72_06485	COG1349	DNA-binding transcription factor activity
GTF72_06490	COG3842	ATPase activity
GTF72_06495	COG0395	ABC-type sugar transport system, permease component
GTF72_06500	COG1175	transmembrane transport
GTF72_06515	COG0811	peptide transport
GTF72_06520	COG0811	peptide transport
GTF72_06525	COG0848	biopolymer transport protein
GTF72_06530	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GTF72_06540	COG1793	dna ligase
GTF72_06550	COG0534	Mate efflux family protein
GTF72_06560	COG3001	Fructosamine kinase
GTF72_06570	COG0791	NLP P60 protein
GTF72_06575	COG0840	transmembrane signaling receptor activity
GTF72_06590	COG1940	carbohydrate kinase activity
GTF72_06615	COG0746	molybdenum cofactor guanylyltransferase activity
GTF72_06620	COG3842	ATPase activity
GTF72_06625	COG4662	Binding-protein-dependent transport system inner membrane component
GTF72_06635	COG2204	response regulator
GTF72_06640	COG3852	Histidine kinase
GTF72_06645	COG0488	(ABC) transporter
GTF72_06650	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GTF72_06680	COG0243	molybdopterin cofactor binding
GTF72_06680	COG3383	formate dehydrogenase (NAD+) activity
GTF72_06685	COG0437	4 iron, 4 sulfur cluster binding
GTF72_06700	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GTF72_06705	COG1666	GTP binding
GTF72_06710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GTF72_06725	COG2996	Protein conserved in bacteria
GTF72_06735	COG3008	intermembrane lipid transfer
GTF72_06740	COG2995	paraquat-inducible protein a
GTF72_06745	COG1132	(ABC) transporter
GTF72_06750	COG1956	GAF domain-containing protein
GTF72_06755	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GTF72_06770	COG0308	aminopeptidase N
GTF72_06775	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GTF72_06845	COG1428	Deoxynucleoside kinase
GTF72_06925	COG4695	Portal protein
GTF72_07005	COG0641	radical SAM
GTF72_07040	COG0308	aminopeptidase N
GTF72_07055	COG0167	dihydroorotate dehydrogenase activity
GTF72_07065	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GTF72_07065	COG0116	Belongs to the methyltransferase superfamily
GTF72_07090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GTF72_07095	COG1067	ATP-dependent peptidase activity
GTF72_07100	COG3120	sequence-specific DNA binding
GTF72_07175	COG1476	TRANSCRIPTIONal
GTF72_07205	COG4128	Pfam Zonular occludens toxin
GTF72_07220	COG1476	TRANSCRIPTIONal
GTF72_07240	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GTF72_07240	COG3064	Membrane
GTF72_07240	COG1073	alpha beta
GTF72_07245	COG2994	toxin metabolic process
GTF72_07270	COG0784	Response regulator, receiver
GTF72_07270	COG2205	protein histidine kinase activity
GTF72_07285	COG3278	Belongs to the heme-copper respiratory oxidase family
GTF72_07300	COG2010	Cytochrome c
GTF72_07310	COG2217	Heavy metal translocating P-type atpase
GTF72_07325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GTF72_07330	COG0589	response to stress
GTF72_07355	COG3842	ATPase activity
GTF72_07365	COG1177	transmembrane transport
GTF72_07375	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GTF72_07390	COG1115	amino acid carrier protein
GTF72_07395	COG1280	lysine exporter protein (LysE YggA)
GTF72_07420	COG3501	Rhs element vgr protein
GTF72_07430	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GTF72_07440	COG2814	Major facilitator Superfamily
GTF72_07445	COG1566	PFAM secretion protein HlyD family protein
GTF72_07450	COG1538	Outer membrane efflux protein
GTF72_07460	COG0513	Belongs to the DEAD box helicase family
GTF72_07470	COG0840	transmembrane signaling receptor activity
GTF72_07475	COG0840	transmembrane signaling receptor activity
GTF72_07475	COG3290	protein histidine kinase activity
GTF72_07480	COG0835	chemotaxis
GTF72_07485	COG2201	protein-glutamate methylesterase activity
GTF72_07495	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GTF72_07500	COG2198	Histidine kinase
GTF72_07500	COG0643	Histidine kinase
GTF72_07500	COG0784	Response regulator, receiver
GTF72_07505	COG0643	Histidine kinase
GTF72_07505	COG2198	Histidine kinase
GTF72_07515	COG0745	RESPONSE REGULATOR receiver
GTF72_07530	COG0415	Belongs to the DNA photolyase family
GTF72_07535	COG0477	Major facilitator Superfamily
GTF72_07540	COG0583	DNA-binding transcription factor activity
GTF72_07550	COG0095	Lipoate-protein ligase
GTF72_07555	COG0443	Heat shock 70 kDa protein
GTF72_07565	COG1643	Atp-dependent helicase
GTF72_07595	COG0443	Heat shock 70 kDa protein
GTF72_07600	COG0443	Heat shock 70 kDa protein
GTF72_07605	COG3706	GGDEF domain
GTF72_07635	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GTF72_07640	COG0602	queuosine metabolic process
GTF72_07645	COG0561	phosphatase activity
GTF72_07655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTF72_07660	COG4597	amino acid ABC transporter
GTF72_07665	COG0765	amino acid transport
GTF72_07670	COG1126	abc transporter atp-binding protein
GTF72_07675	COG0670	Belongs to the BI1 family
GTF72_07680	COG2920	part of a sulfur-relay system
GTF72_07685	COG1254	Belongs to the acylphosphatase family
GTF72_07690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GTF72_07695	COG3706	GGDEF domain
GTF72_07710	COG3437	response regulator, receiver
GTF72_07715	COG0625	glutathione transferase activity
GTF72_07725	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GTF72_07775	COG0372	Belongs to the citrate synthase family
GTF72_07780	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GTF72_07820	COG1129	ABC transporter
GTF72_07845	COG0745	RESPONSE REGULATOR receiver
GTF72_07850	COG2205	protein histidine kinase activity
GTF72_07855	COG3713	MltA-interacting MipA family protein
GTF72_07860	COG2990	Protein conserved in bacteria
GTF72_07870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTF72_07870	COG4191	Histidine kinase
GTF72_07875	COG0471	metal ion transport
GTF72_07885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GTF72_07900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTF72_07910	COG3768	UPF0283 membrane protein
GTF72_07915	COG3106	COG3106 Predicted ATPase
GTF72_07930	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GTF72_07935	COG0494	nUDIX hydrolase
GTF72_07940	COG0814	amino acid
GTF72_07945	COG1760	l-serine dehydratase
GTF72_07950	COG0720	synthase
GTF72_07960	COG0017	Asparaginyl-tRNA synthetase
GTF72_07965	COG0351	phosphomethylpyrimidine kinase
GTF72_07975	COG1448	Aminotransferase
GTF72_07990	COG0840	transmembrane signaling receptor activity
GTF72_07995	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GTF72_08000	COG2943	transferase activity, transferring hexosyl groups
GTF72_08005	COG1609	Transcriptional regulator
GTF72_08015	COG1486	melibiose metabolic process
GTF72_08020	COG1447	Phosphotransferase system cellobiose-specific component IIA
GTF72_08030	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GTF72_08035	COG0726	polysaccharide deacetylase
GTF72_08040	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GTF72_08045	COG1846	Transcriptional regulator
GTF72_08070	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GTF72_08085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GTF72_08090	COG3108	Peptidase M15
GTF72_08095	COG2989	Protein conserved in bacteria
GTF72_08120	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GTF72_08130	COG2814	Major facilitator Superfamily
GTF72_08150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GTF72_08155	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GTF72_08160	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GTF72_08210	COG4139	cobalamin transport
GTF72_08230	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GTF72_08235	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GTF72_08240	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GTF72_08250	COG2925	Exonuclease
GTF72_08255	COG1380	Effector of murein hydrolase LrgA
GTF72_08260	COG1346	cytolysis
GTF72_08290	COG0776	regulation of translation
GTF72_08295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GTF72_08295	COG0072	phenylalanine-tRNA ligase activity
GTF72_08300	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GTF72_08340	COG0322	excinuclease ABC activity
GTF72_08345	COG2197	response regulator
GTF72_08350	COG0417	DNA replication proofreading
GTF72_08355	COG5001	Diguanylate cyclase
GTF72_08365	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GTF72_08370	COG3099	Belongs to the UPF0263 family
GTF72_08385	COG1228	amidohydrolase
GTF72_08390	COG0010	Belongs to the arginase family
GTF72_08395	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GTF72_08400	COG2986	histidine ammonia-lyase
GTF72_08420	COG0277	FAD linked oxidase domain protein
GTF72_08420	COG0247	lactate metabolic process
GTF72_08435	COG2885	chlorophyll binding
GTF72_08455	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GTF72_08465	COG0281	malic enzyme
GTF72_08475	COG2949	membrane
GTF72_08485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GTF72_08495	COG0492	ferredoxin-NADP+ reductase activity
GTF72_08500	COG4988	ABC transporter
GTF72_08505	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GTF72_08510	COG1187	pseudouridine synthase activity
GTF72_08515	COG0009	L-threonylcarbamoyladenylate synthase
GTF72_08520	COG0613	PHP domain protein
GTF72_08530	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GTF72_08535	COG0512	Glutamine amidotransferase of anthranilate synthase
GTF72_08540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GTF72_08545	COG0135	phosphoribosylanthranilate isomerase activity
GTF72_08545	COG0134	indole-3-glycerol-phosphate synthase activity
GTF72_08550	COG0133	tryptophan synthase activity
GTF72_08555	COG0159	tryptophan synthase activity
GTF72_08565	COG1435	thymidine kinase activity
GTF72_08570	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GTF72_08575	COG1801	Protein of unknown function DUF72
GTF72_08580	COG4106	trans-aconitate 2-methyltransferase activity
GTF72_08585	COG0500	methyltransferase
GTF72_08590	COG0189	ligase activity
GTF72_08590	COG4067	protein conserved in archaea
GTF72_08605	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GTF72_08615	COG3852	Histidine kinase
GTF72_08630	COG3070	regulator of competence-specific genes
GTF72_08640	COG2431	L-lysine efflux transmembrane transporter activity
GTF72_08650	COG0076	glutamate decarboxylase activity
GTF72_08655	COG1737	Transcriptional regulator
GTF72_08660	COG1012	belongs to the aldehyde dehydrogenase family
GTF72_08660	COG1454	alcohol dehydrogenase
GTF72_08665	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GTF72_08670	COG2985	domain, Protein
GTF72_08670	COG3273	potassium ion transport
GTF72_08675	COG0542	response to heat
GTF72_08680	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GTF72_08685	COG1278	Cold shock
GTF72_08695	COG1187	pseudouridine synthase activity
GTF72_08700	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GTF72_08700	COG0140	phosphoribosyl-ATP diphosphatase activity
GTF72_08705	COG0107	imidazoleglycerol-phosphate synthase activity
GTF72_08710	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GTF72_08715	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GTF72_08720	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GTF72_08720	COG0131	Imidazoleglycerol-phosphate dehydratase
GTF72_08725	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GTF72_08730	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GTF72_08735	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GTF72_08740	COG1757	Na H antiporter
GTF72_08745	COG2916	Histone family protein nucleoid-structuring protein H-NS
GTF72_08750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTF72_08755	COG0482	sulfurtransferase activity
GTF72_08760	COG2915	High frequency lysogenization protein hflD homolog
GTF72_08765	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GTF72_08775	COG2268	Band 7 protein
GTF72_08785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GTF72_08800	COG0300	oxidoreductase activity
GTF72_08810	COG0501	Belongs to the peptidase M48B family
GTF72_08820	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GTF72_08825	COG2226	methyltransferase
GTF72_08830	COG0156	8-amino-7-oxononanoate synthase activity
GTF72_08835	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GTF72_08840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GTF72_08845	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GTF72_08850	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GTF72_08855	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GTF72_08865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GTF72_08870	COG2203	Gaf domain
GTF72_08870	COG2199	diguanylate cyclase activity
GTF72_08880	COG4120	Belongs to the binding-protein-dependent transport system permease family
GTF72_08890	COG4628	conserved protein (DUF2132)
GTF72_08895	COG3092	negative regulation of chromosome organization
GTF72_08900	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GTF72_08905	COG0280	phosphate acetyltransferase
GTF72_08905	COG0857	belongs to the CobB CobQ family
GTF72_08910	COG0435	Glutathione S-transferase
GTF72_08915	COG4608	Belongs to the ABC transporter superfamily
GTF72_08920	COG0444	Belongs to the ABC transporter superfamily
GTF72_08925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTF72_08930	COG0601	transmembrane transport
GTF72_08950	COG2204	response regulator
GTF72_08955	COG3300	MHYT domain
GTF72_08955	COG5001	Diguanylate cyclase
GTF72_08960	COG4191	Histidine kinase
GTF72_08965	COG5002	protein histidine kinase activity
GTF72_08975	COG2201	protein-glutamate methylesterase activity
GTF72_08990	COG0009	L-threonylcarbamoyladenylate synthase
GTF72_09005	COG1881	PFAM PEBP family protein
GTF72_09030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GTF72_09035	COG0640	Transcriptional regulator
GTF72_09045	COG3706	GGDEF domain
GTF72_09065	COG1946	Acyl-CoA thioesterase
GTF72_09070	COG1522	sequence-specific DNA binding
GTF72_09080	COG0616	signal peptide processing
GTF72_09085	COG1028	Short-chain dehydrogenase reductase Sdr
GTF72_09090	COG2983	Belongs to the UPF0260 family
GTF72_09100	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GTF72_09105	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GTF72_09115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GTF72_09120	COG2832	Protein of unknown function (DUF454)
GTF72_09125	COG0745	RESPONSE REGULATOR receiver
GTF72_09130	COG0583	DNA-binding transcription factor activity
GTF72_09135	COG0778	Nitroreductase
GTF72_09140	COG1024	Enoyl-CoA hydratase
GTF72_09140	COG1250	3-hydroxyacyl-CoA dehydrogenase
GTF72_09145	COG0183	Belongs to the thiolase family
GTF72_09170	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GTF72_09175	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GTF72_09180	COG2982	Protein involved in outer membrane biogenesis
GTF72_09185	COG0572	uridine kinase
GTF72_09190	COG0489	protein tyrosine kinase activity
GTF72_09195	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GTF72_09195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GTF72_09205	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GTF72_09215	COG0517	IMP dehydrogenase activity
GTF72_09215	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GTF72_09215	COG0617	tRNA 3'-terminal CCA addition
GTF72_09220	COG2199	diguanylate cyclase activity
GTF72_09225	COG0314	molybdopterin synthase activity
GTF72_09230	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GTF72_09235	COG0315	cyclic pyranopterin monophosphate synthase activity
GTF72_09240	COG0521	Mo-molybdopterin cofactor biosynthetic process
GTF72_09245	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GTF72_09250	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GTF72_09255	COG2198	Histidine kinase
GTF72_09260	COG2204	response regulator
GTF72_09265	COG0556	nucleotide-excision repair
GTF72_09275	COG4657	Part of a membrane complex involved in electron transport
GTF72_09280	COG2878	Part of a membrane complex involved in electron transport
GTF72_09285	COG4656	Part of a membrane complex involved in electron transport
GTF72_09305	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GTF72_09310	COG0346	lactoylglutathione lyase activity
GTF72_09325	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GTF72_09330	COG2056	Na+-H+ antiporter family
GTF72_09335	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GTF72_09340	COG1286	toxin biosynthetic process
GTF72_09345	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GTF72_09350	COG0285	dihydrofolate synthase activity
GTF72_09355	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GTF72_09360	COG0101	tRNA pseudouridine synthase activity
GTF72_09375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTF72_09375	COG1263	PTS System
GTF72_09375	COG2190	(PTS) system
GTF72_09380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GTF72_09385	COG1940	carbohydrate kinase activity
GTF72_09385	COG1846	Transcriptional regulator
GTF72_09390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GTF72_09390	COG4651	solute:proton antiporter activity
GTF72_09395	COG0367	asparagine synthase
GTF72_09410	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GTF72_09415	COG0563	adenylate kinase activity
GTF72_09420	COG0326	Molecular chaperone. Has ATPase activity
GTF72_09425	COG3710	Transcriptional regulator
GTF72_09440	COG0622	Phosphoesterase
GTF72_09445	COG1090	epimerase
GTF72_09450	COG0300	oxidoreductase activity
GTF72_09455	COG3118	belongs to the thioredoxin family
GTF72_09460	COG0330	HflC and HflK could
GTF72_09465	COG1585	Membrane protein implicated in regulation of membrane protease activity
GTF72_09470	COG0789	Transcriptional regulator
GTF72_09485	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GTF72_09490	COG3115	cell septum assembly
GTF72_09495	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GTF72_09500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GTF72_09505	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTF72_09515	COG2190	(PTS) system
GTF72_09520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTF72_09525	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GTF72_09530	COG1702	phosphate starvation-inducible protein PhoH
GTF72_09540	COG4535	Mg2 and Co2 transporter CorC
GTF72_09545	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GTF72_09550	COG2888	peptidyl-tyrosine sulfation
GTF72_09555	COG0495	leucyl-tRNA aminoacylation
GTF72_09560	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GTF72_09565	COG1466	dna polymerase III delta subunit
GTF72_09570	COG0799	negative regulation of ribosome biogenesis
GTF72_09575	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GTF72_09580	COG0768	penicillin binding
GTF72_09585	COG0772	Belongs to the SEDS family
GTF72_09590	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GTF72_09595	COG1686	Belongs to the peptidase S11 family
GTF72_09600	COG2921	Belongs to the UPF0250 family
GTF72_09605	COG0321	lipoyl(octanoyl) transferase activity
GTF72_09610	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GTF72_09620	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GTF72_09645	COG1596	polysaccharide export
GTF72_09655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GTF72_09685	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GTF72_09695	COG0438	transferase activity, transferring glycosyl groups
GTF72_09705	COG1045	serine acetyltransferase
GTF72_09725	COG0110	maltose O-acetyltransferase activity
GTF72_09730	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GTF72_09735	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GTF72_09740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GTF72_09745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GTF72_09775	COG0366	Alpha amylase catalytic
GTF72_09780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTF72_09780	COG1263	PTS System
GTF72_09785	COG1609	Transcriptional regulator
GTF72_09790	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GTF72_09795	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GTF72_09800	COG2011	ABC-type metal ion transport system permease component
GTF72_09805	COG1464	Belongs to the NlpA lipoprotein family
GTF72_09810	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GTF72_09820	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GTF72_09820	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GTF72_09830	COG3706	GGDEF domain
GTF72_09835	COG1611	Belongs to the LOG family
GTF72_09840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GTF72_09845	COG2363	Small membrane protein
GTF72_09850	COG0583	DNA-binding transcription factor activity
GTF72_09855	COG0301	tRNA thio-modification
GTF72_09855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GTF72_09865	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GTF72_09870	COG1722	exodeoxyribonuclease VII activity
GTF72_09875	COG0142	geranyltranstransferase activity
GTF72_09880	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GTF72_09885	COG0564	pseudouridine synthase activity
GTF72_09890	COG3098	single-species biofilm formation
GTF72_09905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTF72_09915	COG1671	Belongs to the UPF0178 family
GTF72_09920	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GTF72_09925	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GTF72_09930	COG0254	rRNA binding
GTF72_09935	COG1720	tRNA m6t6A37 methyltransferase activity
GTF72_09940	COG0442	prolyl-tRNA aminoacylation
GTF72_09965	COG0047	phosphoribosylformylglycinamidine synthase activity
GTF72_09965	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GTF72_09975	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GTF72_09985	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GTF72_10015	COG0484	heat shock protein binding
GTF72_10020	COG0443	Heat shock 70 kDa protein
GTF72_10025	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GTF72_10030	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GTF72_10035	COG0497	DNA recombination
GTF72_10040	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTF72_10045	COG2914	Belongs to the UPF0125 (RnfH) family
GTF72_10050	COG2867	negative regulation of translational initiation
GTF72_10055	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GTF72_10065	COG0582	viral genome integration into host DNA
GTF72_10075	COG0582	viral genome integration into host DNA
GTF72_10080	COG3064	Membrane
GTF72_10090	COG0739	heme binding
GTF72_10110	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GTF72_10115	COG2207	Transcriptional regulator
GTF72_10125	COG1459	type II secretion system
GTF72_10130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GTF72_10150	COG4796	Type ii and iii secretion system protein
GTF72_10165	COG2165	general secretion pathway protein
GTF72_10175	COG3710	Transcriptional regulator
GTF72_10180	COG0840	transmembrane signaling receptor activity
GTF72_10185	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GTF72_10205	COG1012	belongs to the aldehyde dehydrogenase family
GTF72_10260	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GTF72_10265	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GTF72_10270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GTF72_10290	COG3051	citrate lyase alpha subunit
GTF72_10295	COG2301	Belongs to the HpcH HpaI aldolase family
GTF72_10305	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GTF72_10315	COG3630	sodium ion export across plasma membrane
GTF72_10320	COG0511	ligase activity, forming carbon-carbon bonds
GTF72_10320	COG5016	pyruvate
GTF72_10325	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GTF72_10335	COG4565	transcriptional regulatory protein
GTF72_10350	COG0583	DNA-binding transcription factor activity
GTF72_10360	COG1115	amino acid carrier protein
GTF72_10365	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GTF72_10370	COG0583	DNA-binding transcription factor activity
GTF72_10380	COG1120	ATPase activity
GTF72_10385	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTF72_10390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTF72_10395	COG4592	Periplasmic binding protein
GTF72_10405	COG1028	Short-chain dehydrogenase reductase Sdr
GTF72_10410	COG1169	isochorismate synthase
GTF72_10415	COG1021	2,3-dihydroxybenzoate-AMP ligase
GTF72_10420	COG3433	isochorismatase activity
GTF72_10420	COG1535	isochorismatase
GTF72_10425	COG1584	GPR1 FUN34 yaaH family protein
GTF72_10435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GTF72_10435	COG0519	Catalyzes the synthesis of GMP from XMP
GTF72_10440	COG0516	GMP reductase activity
GTF72_10440	COG0517	IMP dehydrogenase activity
GTF72_10445	COG1570	exodeoxyribonuclease VII activity
GTF72_10460	COG1160	GTP binding
GTF72_10465	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTF72_10470	COG2976	Protein conserved in bacteria
GTF72_10475	COG0124	histidyl-tRNA synthetase
GTF72_10480	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GTF72_10490	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GTF72_10495	COG0105	UTP biosynthetic process
GTF72_10500	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GTF72_10505	COG2975	iron-sulfur cluster assembly
GTF72_10510	COG0633	Ferredoxin
GTF72_10515	COG0443	Heat shock 70 kDa protein
GTF72_10520	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GTF72_10530	COG0822	iron-sulfur transferase activity
GTF72_10535	COG1104	cysteine desulfurase activity
GTF72_10540	COG1959	2 iron, 2 sulfur cluster binding
GTF72_10550	COG0483	inositol monophosphate 1-phosphatase activity
GTF72_10555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GTF72_10560	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GTF72_10565	COG1862	Preprotein translocase
GTF72_10580	COG0517	IMP dehydrogenase activity
GTF72_10590	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GTF72_10595	COG0583	DNA-binding transcription factor activity
GTF72_10600	COG0450	alkyl hydroperoxide reductase
GTF72_10605	COG3142	Participates in the control of copper homeostasis
GTF72_10620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GTF72_10625	COG0581	inorganic phosphate transmembrane transporter activity
GTF72_10635	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GTF72_10640	COG0248	Ppx GppA phosphatase
GTF72_10650	COG5002	protein histidine kinase activity
GTF72_10655	COG0745	RESPONSE REGULATOR receiver
GTF72_10670	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GTF72_10710	COG0542	response to heat
GTF72_10720	COG0564	pseudouridine synthase activity
GTF72_10725	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTF72_10730	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GTF72_10735	COG0077	Prephenate dehydratase
GTF72_10735	COG1605	Chorismate mutase
GTF72_10740	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GTF72_10745	COG5001	Diguanylate cyclase
GTF72_10755	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GTF72_10765	COG0488	(ABC) transporter
GTF72_10775	COG1605	Chorismate mutase
GTF72_10775	COG0287	Prephenate dehydrogenase
GTF72_10780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GTF72_10785	COG3275	phosphorelay sensor kinase activity
GTF72_10790	COG3279	Response regulator of the LytR AlgR family
GTF72_10800	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GTF72_10805	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GTF72_10820	COG1966	Carbon starvation protein
GTF72_10825	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GTF72_10830	COG1047	Peptidyl-prolyl cis-trans
GTF72_10845	COG0196	riboflavin kinase activity
GTF72_10850	COG0728	peptidoglycan biosynthetic process
GTF72_10855	COG0268	Binds directly to 16S ribosomal RNA
GTF72_10860	COG0640	Transcriptional regulator
GTF72_10865	COG0583	DNA-binding transcription factor activity
GTF72_10870	COG1283	sodium-dependent phosphate transmembrane transporter activity
GTF72_10880	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GTF72_10885	COG0730	response to heat
GTF72_10890	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
GTF72_10895	COG0494	nUDIX hydrolase
GTF72_10905	COG0667	Aldo Keto reductase
GTF72_10915	COG2204	response regulator
GTF72_10920	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GTF72_10940	COG0513	Belongs to the DEAD box helicase family
GTF72_10965	COG3153	acetyltransferase
GTF72_10970	COG3154	lipid carrier protein
GTF72_10980	COG0826	peptidase U32
GTF72_10985	COG0826	peptidase U32
GTF72_11010	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GTF72_11020	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GTF72_11025	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GTF72_11030	COG0195	Participates in both transcription termination and antitermination
GTF72_11035	COG0779	Required for maturation of 30S ribosomal subunits
GTF72_11050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GTF72_11060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GTF72_11065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GTF72_11070	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GTF72_11075	COG1534	Rna-binding protein
GTF72_11080	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GTF72_11085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GTF72_11090	COG2027	D-alanyl-D-alanine carboxypeptidase
GTF72_11095	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GTF72_11100	COG0739	heme binding
GTF72_11115	COG0316	Belongs to the HesB IscA family
GTF72_11120	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GTF72_11130	COG0628	permease
GTF72_11135	COG2813	Specifically methylates the guanine in position
GTF72_11140	COG2205	protein histidine kinase activity
GTF72_11140	COG0784	Response regulator, receiver
GTF72_11145	COG0747	negative chemotaxis
GTF72_11150	COG0601	transmembrane transport
GTF72_11155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTF72_11160	COG0444	Belongs to the ABC transporter superfamily
GTF72_11165	COG4608	Belongs to the ABC transporter superfamily
GTF72_11175	COG2971	BadF BadG BcrA BcrD
GTF72_11195	COG3842	ATPase activity
GTF72_11205	COG1840	ABC-type Fe3 transport system, periplasmic component
GTF72_11210	COG0004	ammonium transporteR
GTF72_11215	COG0347	Belongs to the P(II) protein family
GTF72_11220	COG3112	Uncharacterised protein family (UPF0231)
GTF72_11225	COG1049	propionate catabolic process, 2-methylcitrate cycle
GTF72_11230	COG1752	Esterase of the alpha-beta hydrolase superfamily
GTF72_11235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GTF72_11240	COG1643	Atp-dependent helicase
GTF72_11250	COG1489	DNA binding
GTF72_11260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GTF72_11270	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GTF72_11275	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GTF72_11280	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GTF72_11285	COG0842	Transport permease protein
GTF72_11290	COG1131	(ABC) transporter
GTF72_11295	COG0659	secondary active sulfate transmembrane transporter activity
GTF72_11300	COG0288	reversible hydration of carbon dioxide
GTF72_11315	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GTF72_11320	COG3107	peptidoglycan biosynthetic process
GTF72_11325	COG0792	nuclease activity
GTF72_11330	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GTF72_11335	COG2823	Periplasmic or secreted lipoprotein
GTF72_11340	COG2969	positive regulation of protein catabolic process
GTF72_11345	COG0625	glutathione transferase activity
GTF72_11350	COG2857	Cytochrome c1
GTF72_11355	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GTF72_11360	COG0723	plastoquinol--plastocyanin reductase activity
GTF72_11365	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GTF72_11370	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GTF72_11375	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GTF72_11385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GTF72_11390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GTF72_11395	COG0335	large ribosomal subunit rRNA binding
GTF72_11400	COG0336	Belongs to the RNA methyltransferase TrmD family
GTF72_11405	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GTF72_11410	COG0228	four-way junction DNA binding
GTF72_11415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GTF72_11420	COG4137	Cytochrome C assembly protein
GTF72_11425	COG4536	flavin adenine dinucleotide binding
GTF72_11430	COG1854	S-ribosylhomocysteine lyase activity
GTF72_11435	COG2918	glutathione biosynthetic process
GTF72_11440	COG0612	Peptidase, M16
GTF72_11445	COG1238	metal cluster binding
GTF72_11455	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GTF72_11460	COG0511	ligase activity, forming carbon-carbon bonds
GTF72_11460	COG5016	pyruvate
GTF72_11465	COG3630	sodium ion export across plasma membrane
GTF72_11510	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GTF72_11515	COG0527	aspartate kinase activity
GTF72_11520	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GTF72_11530	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GTF72_11540	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GTF72_11545	COG4208	sulfate ABC transporter
GTF72_11565	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GTF72_11570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GTF72_11580	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GTF72_11585	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GTF72_11590	COG0585	pseudouridine synthase activity
GTF72_11595	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GTF72_11600	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GTF72_11605	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GTF72_11610	COG1968	undecaprenyl-diphosphatase activity
GTF72_11615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GTF72_11620	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GTF72_11625	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GTF72_11635	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GTF72_11640	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GTF72_11645	COG1610	YqeY-like protein
GTF72_11650	COG0358	DNA primase activity
GTF72_11665	COG0582	viral genome integration into host DNA
GTF72_11690	COG2003	Belongs to the UPF0758 family
GTF72_11720	COG0739	heme binding
GTF72_11730	COG4969	Belongs to the N-Me-Phe pilin family
GTF72_11745	COG0328	RNA-DNA hybrid ribonuclease activity
GTF72_11800	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GTF72_11805	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GTF72_11810	COG1349	DNA-binding transcription factor activity
GTF72_11830	COG1279	arginine transmembrane transporter activity
GTF72_11835	COG0668	transmembrane transport
GTF72_11840	COG0191	fructose-bisphosphate aldolase activity
GTF72_11845	COG0126	phosphoglycerate kinase activity
GTF72_11850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GTF72_11855	COG4771	TonB-dependent receptor
GTF72_11860	COG0583	DNA-binding transcription factor activity
GTF72_11865	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GTF72_11870	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GTF72_11880	COG2356	endonuclease I
GTF72_11885	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GTF72_11890	COG0189	ligase activity
GTF72_11895	COG1678	Uncharacterized ACR, COG1678
GTF72_11900	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GTF72_11925	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GTF72_11930	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GTF72_11935	COG0762	integral membrane protein
GTF72_11940	COG1872	DUF167
GTF72_11950	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GTF72_11955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GTF72_11960	COG2066	Belongs to the glutaminase family
GTF72_11970	COG1194	a g-specific adenine glycosylase
GTF72_11975	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GTF72_11980	COG0741	lytic transglycosylase activity
GTF72_12035	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GTF72_12040	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GTF72_12045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GTF72_12050	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GTF72_12055	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GTF72_12060	COG2967	ApaG domain
GTF72_12065	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GTF72_12075	COG3610	response to peptide
GTF72_12080	COG2966	Psort location CytoplasmicMembrane, score
GTF72_12085	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GTF72_12090	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GTF72_12095	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GTF72_12100	COG0142	geranyltranstransferase activity
GTF72_12105	COG0531	amino acid
GTF72_12110	COG0039	L-malate dehydrogenase activity
GTF72_12115	COG1438	arginine binding
GTF72_12120	COG2358	TRAP transporter, solute receptor (TAXI family
GTF72_12130	COG0589	response to stress
GTF72_12150	COG2235	arginine
GTF72_12155	COG0312	modulator of DNA gyrase
GTF72_12160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GTF72_12165	COG3164	Protein of unknown function
GTF72_12170	COG1530	ribonuclease E activity
GTF72_12175	COG0424	maF-like protein
GTF72_12180	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GTF72_12185	COG1792	Involved in formation and maintenance of cell shape
GTF72_12190	COG1077	Cell shape determining protein MreB Mrl
GTF72_12235	COG1459	type II secretion system
GTF72_12240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GTF72_12250	COG3267	Type II secretory pathway component ExeA
GTF72_12250	COG3409	Peptidoglycan-binding domain 1 protein
GTF72_12275	COG2199	diguanylate cyclase activity
GTF72_12275	COG2200	EAL domain
GTF72_12280	COG0629	single-stranded DNA binding
GTF72_12295	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GTF72_12305	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GTF72_12310	COG0527	aspartate kinase activity
GTF72_12315	COG0646	methionine synthase
GTF72_12315	COG1410	methionine synthase
GTF72_12385	COG0175	sulfate reduction
GTF72_12395	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GTF72_12420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GTF72_12425	COG0735	belongs to the Fur family
GTF72_12445	COG0432	Pfam Uncharacterised protein family UPF0047
GTF72_12450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GTF72_12465	COG0359	binds to the 23S rRNA
GTF72_12470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GTF72_12475	COG2965	DNA replication, synthesis of RNA primer
GTF72_12480	COG0360	Binds together with S18 to 16S ribosomal RNA
GTF72_12490	COG2906	2 iron, 2 sulfur cluster binding
GTF72_12495	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GTF72_12500	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GTF72_12505	COG0049	tRNA binding
GTF72_12520	COG2923	Belongs to the DsrF TusC family
GTF72_12525	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GTF72_12530	COG2964	Protein conserved in bacteria
GTF72_12535	COG0545	Peptidyl-prolyl cis-trans isomerase
GTF72_12545	COG2900	Belongs to the SlyX family
GTF72_12550	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GTF72_12555	COG0330	HflC and HflK could
GTF72_12560	COG0330	HflC and HflK could
GTF72_12565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GTF72_12570	COG1923	regulation of RNA biosynthetic process
GTF72_12575	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GTF72_12580	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GTF72_12590	COG0802	atpase or kinase
GTF72_12595	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GTF72_12650	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GTF72_12655	COG1162	GTPase activity
GTF72_12660	COG0688	phosphatidylethanolamine metabolic process
GTF72_12665	COG0471	metal ion transport
GTF72_12675	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GTF72_12680	COG4942	peptidase
GTF72_12695	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GTF72_12700	COG2816	NAD+ diphosphatase activity
GTF72_12705	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GTF72_12710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GTF72_12715	COG0085	RNA polymerase activity
GTF72_12720	COG0222	ribosome binding
GTF72_12725	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GTF72_12735	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GTF72_12740	COG0250	Participates in transcription elongation, termination and antitermination
GTF72_12745	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GTF72_12750	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GTF72_12775	COG1072	(Pantothenic acid kinase))
GTF72_12785	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GTF72_12795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GTF72_12840	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GTF72_12855	COG3118	belongs to the thioredoxin family
GTF72_12860	COG0513	Belongs to the DEAD box helicase family
GTF72_12865	COG0248	Ppx GppA phosphatase
GTF72_12870	COG0784	Response regulator, receiver
GTF72_12870	COG2205	protein histidine kinase activity
GTF72_12875	COG2814	Major facilitator Superfamily
GTF72_12890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GTF72_12895	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GTF72_12900	COG0511	ligase activity, forming carbon-carbon bonds
GTF72_12905	COG0439	Biotin carboxylase
GTF72_12910	COG2264	protein methyltransferase activity
GTF72_12915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GTF72_12920	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GTF72_12925	COG1609	Transcriptional regulator
GTF72_12930	COG0129	dihydroxy-acid dehydratase activity
GTF72_12935	COG3265	gluconokinase activity
GTF72_12945	COG0800	Aldolase
GTF72_12965	COG0840	transmembrane signaling receptor activity
GTF72_12970	COG1982	Orn Lys Arg decarboxylase major
GTF72_12980	COG3710	Transcriptional regulator
GTF72_12985	COG0789	Transcriptional regulator
GTF72_13000	COG0151	Belongs to the GarS family
GTF72_13010	COG0776	regulation of translation
GTF72_13015	COG1253	flavin adenine dinucleotide binding
GTF72_13020	COG1940	carbohydrate kinase activity
GTF72_13030	COG3068	Protein conserved in bacteria
GTF72_13040	COG1573	uracil-dna glycosylase
GTF72_13045	COG0668	transmembrane transport
GTF72_13050	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GTF72_13055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GTF72_13100	COG1454	alcohol dehydrogenase
GTF72_13100	COG1012	belongs to the aldehyde dehydrogenase family
GTF72_13105	COG0318	PFAM AMP-dependent synthetase and ligase
GTF72_13135	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GTF72_13140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GTF72_13145	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GTF72_13145	COG0662	Cupin 2, conserved barrel domain protein
GTF72_13150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GTF72_13185	COG1519	Transferase
GTF72_13215	COG3642	lipopolysaccharide core region biosynthetic process
GTF72_13220	COG0859	PFAM glycosyl transferase family 9
GTF72_13225	COG0463	Glycosyl transferase, family 2
GTF72_13230	COG0859	PFAM glycosyl transferase family 9
GTF72_13235	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GTF72_13240	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GTF72_13250	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GTF72_13255	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GTF72_13260	COG2003	Belongs to the UPF0758 family
GTF72_13270	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GTF72_13280	COG1309	transcriptional regulator
GTF72_13285	COG1560	Kdo2-lipid A biosynthetic process
GTF72_13290	COG1560	Kdo2-lipid A biosynthetic process
GTF72_13295	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GTF72_13300	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GTF72_13305	COG1561	YicC-like family, N-terminal region
GTF72_13310	COG2862	Uncharacterized protein family, UPF0114
GTF72_13315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTF72_13315	COG1263	PTS System
GTF72_13320	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GTF72_13340	COG1120	ATPase activity
GTF72_13345	COG4774	siderophore transport
GTF72_13350	COG1132	(ABC) transporter
GTF72_13365	COG0514	ATP-dependent DNA helicase (RecQ)
GTF72_13370	COG2962	Rard protein
GTF72_13385	COG1280	lysine exporter protein (LysE YggA)
GTF72_13390	COG0210	DNA helicase
GTF72_13400	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GTF72_13405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GTF72_13455	COG3621	Patatin-like phospholipase
GTF72_13480	COG2131	deaminase
GTF72_13490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTF72_13500	COG0747	negative chemotaxis
GTF72_13550	COG1309	transcriptional regulator
GTF72_13555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTF72_13560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GTF72_13565	COG2960	long-chain fatty acid transporting porin activity
GTF72_13570	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GTF72_13575	COG0583	DNA-binding transcription factor activity
GTF72_13620	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GTF72_13625	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GTF72_13630	COG1739	Uncharacterized protein family UPF0029
GTF72_13640	COG0183	Belongs to the thiolase family
GTF72_13645	COG0583	DNA-binding transcription factor activity
GTF72_13650	COG2814	Major facilitator Superfamily
GTF72_13655	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GTF72_13660	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GTF72_13665	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GTF72_13670	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GTF72_13675	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GTF72_13680	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GTF72_13685	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GTF72_13695	COG0356	it plays a direct role in the translocation of protons across the membrane
GTF72_13700	COG3312	ion transport
GTF72_13705	COG1475	DNA binding
GTF72_13710	COG1192	Involved in chromosome partitioning
GTF72_13720	COG0445	tRNA wobble uridine modification
GTF72_13725	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GTF72_13730	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GTF72_13735	COG0706	membrane insertase activity
GTF72_13745	COG0594	ribonuclease P activity
GTF72_13750	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GTF72_13755	COG1126	abc transporter atp-binding protein
GTF72_13800	COG0217	transcriptional regulatory protein
GTF72_13805	COG2084	Dehydrogenase
GTF72_13820	COG2909	trisaccharide binding
GTF72_13825	COG0058	SHG alpha-glucan phosphorylase activity
GTF72_13830	COG1640	4-alpha-glucanotransferase
GTF72_13835	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GTF72_13845	COG3501	Rhs element vgr protein
GTF72_13880	COG0471	metal ion transport
GTF72_13885	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GTF72_13925	COG0671	phosphoesterase, PA-phosphatase related
GTF72_13930	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GTF72_13940	COG1999	signal sequence binding
GTF72_13955	COG0786	glutamate:sodium symporter activity
GTF72_13975	COG1566	PFAM secretion protein HlyD family protein
GTF72_13985	COG3706	GGDEF domain
GTF72_14000	COG0813	purine-nucleoside phosphorylase activity
GTF72_14005	COG3272	Protein of unknown function (DUF1722)
GTF72_14015	COG0415	Belongs to the DNA photolyase family
GTF72_14020	COG1376	ErfK ybiS ycfS ynhG family protein
GTF72_14020	COG1388	LysM domain
GTF72_14030	COG0513	Belongs to the DEAD box helicase family
GTF72_14035	COG1770	oligopeptidase
GTF72_14065	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GTF72_14070	COG0573	inorganic phosphate transmembrane transporter activity
GTF72_14075	COG0581	inorganic phosphate transmembrane transporter activity
GTF72_14080	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GTF72_14100	COG0659	secondary active sulfate transmembrane transporter activity
GTF72_14110	COG0739	heme binding
GTF72_14115	COG3300	MHYT domain
GTF72_14115	COG5001	Diguanylate cyclase
GTF72_14120	COG0583	DNA-binding transcription factor activity
GTF72_14125	COG2814	Major facilitator Superfamily
GTF72_14145	COG1301	dicarboxylic acid transport
GTF72_14155	COG1342	Belongs to the UPF0251 family
GTF72_14185	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GTF72_14190	COG0673	inositol 2-dehydrogenase activity
GTF72_14200	COG2771	luxR family
GTF72_14200	COG2200	EAL domain
GTF72_14205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GTF72_14215	COG0564	pseudouridine synthase activity
GTF72_14305	COG3501	Rhs element vgr protein
GTF72_14325	COG1129	ABC transporter
GTF72_14330	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTF72_14335	COG1879	ABC-type sugar transport system periplasmic component
GTF72_14340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTF72_14345	COG1609	Transcriptional regulator
GTF72_14355	COG3201	nicotinamide mononucleotide transporter
GTF72_14360	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GTF72_14370	COG0584	glycerophosphoryl diester phosphodiesterase
GTF72_14375	COG2271	Major facilitator Superfamily
GTF72_14410	COG0579	oxidoreductase
GTF72_14420	COG0242	peptide deformylase activity
GTF72_14430	COG1320	monovalent cation:proton antiporter activity
GTF72_14435	COG2212	antiporter activity
GTF72_14455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GTF72_14455	COG2111	Na H antiporter
GTF72_14465	COG0589	response to stress
GTF72_14470	COG0814	amino acid
GTF72_14485	COG3530	Putative quorum-sensing-regulated virulence factor
GTF72_14495	COG5001	Diguanylate cyclase
GTF72_14495	COG5002	protein histidine kinase activity
GTF72_14500	COG1278	Cold shock
GTF72_14515	COG2304	oxidoreductase activity
GTF72_14535	COG0714	Associated with various cellular activities
GTF72_14540	COG0840	transmembrane signaling receptor activity
GTF72_14555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GTF72_14560	COG2195	Cleaves the N-terminal amino acid of tripeptides
GTF72_14570	COG3604	Transcriptional regulator
GTF72_14575	COG1017	nitric oxide dioxygenase activity
GTF72_14575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GTF72_14580	COG1278	Cold shock
GTF72_14585	COG3036	rescue of stalled ribosome
GTF72_14610	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GTF72_14610	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GTF72_14615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GTF72_14625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GTF72_14635	COG0516	GMP reductase activity
GTF72_14675	COG0513	Belongs to the DEAD box helicase family
GTF72_14680	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GTF72_14685	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GTF72_14690	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GTF72_14695	COG3437	response regulator, receiver
GTF72_14695	COG0784	Response regulator, receiver
GTF72_14700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTF72_14700	COG4191	Histidine kinase
GTF72_14710	COG1757	Na H antiporter
GTF72_14715	COG2814	Major facilitator Superfamily
GTF72_14725	COG3706	GGDEF domain
GTF72_14730	COG3240	lipase activity
GTF72_14750	COG5380	lipid catabolic process
GTF72_14775	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTF72_14780	COG4605	iron ion homeostasis
GTF72_14785	COG4604	ABC transporter, ATP-binding protein
GTF72_14790	COG2207	Transcriptional regulator
GTF72_14805	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GTF72_14825	COG0745	RESPONSE REGULATOR receiver
GTF72_14835	COG3623	hexulose-6-phosphate isomerase
GTF72_14840	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GTF72_14845	COG0561	phosphatase activity
GTF72_14875	COG3038	cytochrome b561
GTF72_14880	COG0366	Alpha amylase catalytic
GTF72_14905	COG0745	RESPONSE REGULATOR receiver
GTF72_14910	COG5002	protein histidine kinase activity
GTF72_14935	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GTF72_14950	COG2814	Major facilitator Superfamily
GTF72_14965	COG1686	Belongs to the peptidase S11 family
GTF72_14995	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GTF72_14995	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GTF72_15000	COG0509	glycine decarboxylation via glycine cleavage system
GTF72_15005	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GTF72_15015	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GTF72_15025	COG3039	Transposase
GTF72_15060	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GTF72_15065	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GTF72_15120	COG1028	Short-chain dehydrogenase reductase Sdr
GTF72_15155	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GTF72_15180	COG0494	nUDIX hydrolase
GTF72_15200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTF72_15205	COG3040	lipid binding
GTF72_15235	COG3041	Addiction module toxin RelE StbE family
GTF72_15340	COG1619	proteins homologs of microcin C7 resistance protein MccF
GTF72_15395	COG0346	lactoylglutathione lyase activity
GTF72_15415	COG3040	lipid binding
GTF72_15430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GTF72_15440	COG1280	lysine exporter protein (LysE YggA)
GTF72_15625	COG3549	Plasmid maintenance system killer
GTF72_15630	COG3093	addiction module antidote protein HigA
GTF72_15650	COG0384	phenazine biosynthesis protein PhzF
GTF72_15680	COG0346	lactoylglutathione lyase activity
GTF72_15705	COG3040	lipid binding
GTF72_15760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTF72_15860	COG1619	proteins homologs of microcin C7 resistance protein MccF
GTF72_15885	COG3040	lipid binding
GTF72_15940	COG4977	sequence-specific DNA binding
GTF72_16030	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
GTF72_16035	COG2944	sequence-specific DNA binding
GTF72_16050	COG3039	Transposase
GTF72_16075	COG0346	lactoylglutathione lyase activity
GTF72_16230	COG0346	lactoylglutathione lyase activity
GTF72_16250	COG1328	CTP reductase activity
GTF72_16255	COG0602	queuosine metabolic process
GTF72_16265	COG0189	ligase activity
GTF72_16265	COG4067	protein conserved in archaea
GTF72_16270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTF72_16270	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GTF72_16270	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTF72_16275	COG1105	Belongs to the carbohydrate kinase PfkB family
GTF72_16280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTF72_16280	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTF72_16285	COG1609	Transcriptional regulator
GTF72_16290	COG0420	3'-5' exonuclease activity
GTF72_16295	COG0419	ATPase involved in DNA repair
GTF72_16300	COG0784	Response regulator, receiver
GTF72_16300	COG2205	protein histidine kinase activity
GTF72_16305	COG0156	8-amino-7-oxononanoate synthase activity
GTF72_16320	COG0523	cobalamin synthesis protein
GTF72_16335	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GTF72_16335	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GTF72_16335	COG1013	pyruvate-flavodoxin oxidoreductase activity
GTF72_16335	COG0674	pyruvate-flavodoxin oxidoreductase activity
GTF72_16340	COG2205	protein histidine kinase activity
GTF72_16345	COG0745	RESPONSE REGULATOR receiver
GTF72_16350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GTF72_16355	COG0586	Pfam SNARE associated Golgi protein
GTF72_16365	COG2200	EAL domain
GTF72_16375	COG3038	cytochrome b561
GTF72_16385	COG2116	formate transmembrane transporter activity
GTF72_16390	COG0583	DNA-binding transcription factor activity
GTF72_16400	COG3593	DNA synthesis involved in DNA repair
GTF72_16405	COG0737	Belongs to the 5'-nucleotidase family
GTF72_16420	COG2824	Alkylphosphonate utilization operon protein PhnA
GTF72_16470	COG3706	GGDEF domain
GTF72_16485	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GTF72_16490	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GTF72_16500	COG0745	RESPONSE REGULATOR receiver
GTF72_16515	COG3140	Belongs to the UPF0181 family
GTF72_16520	COG0023	Translation Initiation Factor
GTF72_16540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTF72_16540	COG1042	CoA-binding domain protein
GTF72_16540	COG0045	succinate-CoA ligase (ADP-forming) activity
GTF72_16545	COG0583	DNA-binding transcription factor activity
GTF72_16550	COG1629	transport
GTF72_16550	COG4771	TonB-dependent receptor
GTF72_16565	COG2050	protein possibly involved in aromatic compounds catabolism
GTF72_16585	COG0625	glutathione transferase activity
GTF72_16600	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GTF72_16605	COG4172	Belongs to the ABC transporter superfamily
GTF72_16610	COG4239	(ABC) transporter, permease
GTF72_16615	COG4174	ABC transporter (Permease)
GTF72_16620	COG4166	transmembrane transport
GTF72_16645	COG3104	oligopeptide transport
GTF72_16665	COG3842	ATPase activity
GTF72_16675	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GTF72_16685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GTF72_16690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GTF72_16695	COG1011	Hydrolase
GTF72_16705	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GTF72_16710	COG1970	mechanosensitive ion channel activity
GTF72_16715	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GTF72_16720	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GTF72_16720	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GTF72_16725	COG0302	gtp cyclohydrolase
GTF72_16735	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GTF72_16745	COG2897	thiosulfate sulfurtransferase activity
GTF72_16750	COG2390	Transcriptional regulator
GTF72_16760	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GTF72_16785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GTF72_16810	COG0583	DNA-binding transcription factor activity
GTF72_16815	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GTF72_16855	COG0446	pyridine nucleotide-disulphide oxidoreductase
GTF72_16900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTF72_16900	COG1263	PTS System
GTF72_16910	COG1621	beta-fructofuranosidase activity
GTF72_16915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTF72_16920	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GTF72_16930	COG2885	chlorophyll binding
GTF72_16935	COG0545	Peptidyl-prolyl cis-trans isomerase
GTF72_16940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GTF72_16945	COG0840	transmembrane signaling receptor activity
GTF72_16950	COG3069	C4-dicarboxylate transmembrane transporter activity
GTF72_16955	COG1760	l-serine dehydratase
GTF72_16975	COG1609	Transcriptional regulator
GTF72_16980	COG2197	response regulator
GTF72_16985	COG3850	Histidine kinase
GTF72_16990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GTF72_17000	COG0243	molybdopterin cofactor binding
GTF72_17020	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GTF72_17025	COG2197	response regulator
GTF72_17030	COG3851	Histidine kinase
GTF72_17035	COG2271	Major facilitator Superfamily
GTF72_17040	COG1840	ABC-type Fe3 transport system, periplasmic component
GTF72_17050	COG3842	ATPase activity
GTF72_17055	COG3243	poly(R)-hydroxyalkanoic acid synthase
GTF72_17065	COG0183	Belongs to the thiolase family
GTF72_17075	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GTF72_17080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GTF72_17095	COG3706	GGDEF domain
GTF72_17100	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GTF72_17110	COG1979	alcohol dehydrogenase
GTF72_17125	COG4191	Histidine kinase
GTF72_17135	COG2271	Major facilitator Superfamily
GTF72_17140	COG0469	pyruvate kinase activity
GTF72_17145	COG2205	protein histidine kinase activity
GTF72_17145	COG0784	Response regulator, receiver
GTF72_17145	COG2198	Histidine kinase
GTF72_17150	COG1879	ABC-type sugar transport system periplasmic component
GTF72_17155	COG1803	Methylglyoxal synthase
GTF72_17160	COG1335	isochorismatase
GTF72_17165	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GTF72_17180	COG0210	DNA helicase
GTF72_17185	COG1289	transmembrane transporter activity
GTF72_17215	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GTF72_17220	COG4149	molybdate abc transporter
GTF72_17225	COG0725	ABC transporter, periplasmic molybdate-binding protein
GTF72_17230	COG1492	cobalamin metabolic process
GTF72_17270	COG5002	protein histidine kinase activity
GTF72_17270	COG0784	Response regulator, receiver
GTF72_17275	COG1879	ABC-type sugar transport system periplasmic component
GTF72_17285	COG2827	Endonuclease containing a URI domain
GTF72_17300	COG2926	Belongs to the UPF0265 family
GTF72_17310	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GTF72_17315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GTF72_17320	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GTF72_17325	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GTF72_17330	COG0247	lactate metabolic process
GTF72_17335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GTF72_17340	COG3118	belongs to the thioredoxin family
GTF72_17370	COG0583	DNA-binding transcription factor activity
GTF72_17375	COG4160	amino acid transport
GTF72_17380	COG4215	(ABC) transporter
GTF72_17385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTF72_17390	COG1126	abc transporter atp-binding protein
GTF72_17400	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GTF72_17410	COG0494	nUDIX hydrolase
GTF72_17415	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GTF72_17425	COG1309	transcriptional regulator
GTF72_17430	COG0513	Belongs to the DEAD box helicase family
GTF72_17435	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GTF72_17440	COG0814	amino acid
GTF72_17445	COG0840	transmembrane signaling receptor activity
GTF72_17450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GTF72_17455	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GTF72_17465	COG1984	allophanate hydrolase subunit 2
GTF72_17480	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GTF72_17485	COG4181	ATPase activity
GTF72_17495	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GTF72_17500	COG5001	Diguanylate cyclase
GTF72_17500	COG1716	ATPase activity
GTF72_17510	COG0484	heat shock protein binding
GTF72_17550	COG0546	phosphoglycolate phosphatase activity
GTF72_17565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTF72_17570	COG1368	sulfuric ester hydrolase activity
GTF72_17580	COG0513	Belongs to the DEAD box helicase family
GTF72_17595	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GTF72_17605	COG3046	protein related to deoxyribodipyrimidine photolyase
GTF72_17610	COG3397	chitin binding
GTF72_17615	COG3227	Zinc metalloprotease (Elastase)
GTF72_17625	COG0010	Belongs to the arginase family
GTF72_17630	COG1166	arginine decarboxylase activity
GTF72_17640	COG2239	Acts as a magnesium transporter
GTF72_17645	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GTF72_17650	COG0459	protein refolding
GTF72_17660	COG0527	aspartate kinase activity
GTF72_17665	COG0662	Cupin 2, conserved barrel domain protein
GTF72_17670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GTF72_17675	COG0456	acetyltransferase
GTF72_17685	COG3186	Phenylalanine-4-hydroxylase
GTF72_17690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GTF72_17705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GTF72_17730	COG1253	flavin adenine dinucleotide binding
GTF72_17735	COG1765	OsmC-like protein
GTF72_17760	COG0531	amino acid
GTF72_17765	COG3706	GGDEF domain
GTF72_17775	COG3279	Response regulator of the LytR AlgR family
GTF72_17780	COG3275	phosphorelay sensor kinase activity
GTF72_17795	COG1136	(ABC) transporter
GTF72_17795	COG0577	efflux transmembrane transporter activity
GTF72_17800	COG1136	(ABC) transporter
GTF72_17810	COG4989	oxidoreductase activity
GTF72_17815	COG0366	Alpha amylase catalytic
GTF72_17825	COG2067	long-chain fatty acid transport protein
GTF72_17830	COG2267	carboxylic ester hydrolase activity
GTF72_17840	COG3227	Zinc metalloprotease (Elastase)
GTF72_17850	COG3047	cAMP biosynthetic process
GTF72_17860	COG1686	Belongs to the peptidase S11 family
GTF72_17865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GTF72_17870	COG1271	oxidase subunit
GTF72_17875	COG1294	oxidase, subunit
GTF72_17890	COG3048	D-serine ammonia-lyase activity
GTF72_17895	COG0583	DNA-binding transcription factor activity
GTF72_17940	COG1063	alcohol dehydrogenase
GTF72_17965	COG0346	lactoylglutathione lyase activity
GTF72_17985	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GTF72_17990	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GTF72_17995	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GTF72_18000	COG0363	glucosamine-6-phosphate deaminase activity
GTF72_18005	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GTF72_18030	COG1929	Belongs to the glycerate kinase type-1 family
GTF72_18035	COG2610	gluconate transmembrane transporter activity
GTF72_18040	COG3835	regulator
GTF72_18050	COG0748	coenzyme F420 binding
GTF72_18055	COG3721	Heme iron utilization protein
GTF72_18065	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GTF72_18070	COG0811	peptide transport
GTF72_18075	COG0848	biopolymer transport protein
GTF72_18080	COG4558	Periplasmic binding protein
GTF72_18085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTF72_18090	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GTF72_18125	COG3217	Mosc domain protein beta barrel domain protein
GTF72_18125	COG0633	Ferredoxin
GTF72_18125	COG0633	Ferredoxin
GTF72_18125	COG3217	Mosc domain protein beta barrel domain protein
GTF72_18130	COG0418	dihydroorotase activity
GTF72_18140	COG3152	Membrane
GTF72_18150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GTF72_18155	COG2354	Protein conserved in bacteria
GTF72_18160	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GTF72_18165	COG1278	Cold shock
GTF72_18190	COG3706	GGDEF domain
GTF72_18195	COG1349	DNA-binding transcription factor activity
GTF72_18210	COG3833	ABC-type maltose transport systems, permease component
GTF72_18215	COG1175	transmembrane transport
GTF72_18225	COG3842	ATPase activity
GTF72_18230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTF72_18245	COG0393	Putative heavy-metal-binding
GTF72_18255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GTF72_18260	COG0784	Response regulator, receiver
GTF72_18260	COG0835	chemotaxis
GTF72_18265	COG1846	Transcriptional regulator
GTF72_18270	COG3706	GGDEF domain
GTF72_18305	COG0583	DNA-binding transcription factor activity
GTF72_18310	COG5001	Diguanylate cyclase
GTF72_18320	COG1741	Belongs to the pirin family
GTF72_18325	COG3123	guanosine phosphorylase activity
GTF72_18335	COG2211	Major facilitator Superfamily
GTF72_18340	COG0840	transmembrane signaling receptor activity
GTF72_18345	COG1067	ATP-dependent peptidase activity
GTF72_18355	COG4172	Belongs to the ABC transporter superfamily
GTF72_18380	COG0583	DNA-binding transcription factor activity
GTF72_18390	COG1620	l-lactate permease
GTF72_18405	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GTF72_18415	COG0840	transmembrane signaling receptor activity
GTF72_18425	COG0513	Belongs to the DEAD box helicase family
GTF72_18430	COG0583	DNA-binding transcription factor activity
GTF72_18440	COG1902	pentaerythritol trinitrate reductase activity
GTF72_18450	COG1132	(ABC) transporter
GTF72_18460	COG1902	pentaerythritol trinitrate reductase activity
GTF72_18470	COG1280	lysine exporter protein (LysE YggA)
GTF72_18475	COG2207	Transcriptional regulator
GTF72_18495	COG1846	Transcriptional regulator
GTF72_18500	COG1764	response to oxidative stress
GTF72_18505	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GTF72_18510	COG0697	spore germination
GTF72_18520	COG0700	Nucleoside recognition
GTF72_18525	COG3366	ferrous iron transmembrane transporter activity
GTF72_18530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GTF72_18540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GTF72_18545	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GTF72_18550	COG2259	Doxx family
GTF72_18575	COG0363	glucosamine-6-phosphate deaminase activity
GTF72_18590	COG4580	involved in the transport of maltose and maltodextrins
GTF72_18605	COG0840	transmembrane signaling receptor activity
GTF72_18620	COG0840	transmembrane signaling receptor activity
GTF72_18630	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GTF72_18635	COG1126	abc transporter atp-binding protein
GTF72_18645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTF72_18650	COG4597	amino acid ABC transporter
GTF72_18655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GTF72_18665	COG0739	heme binding
GTF72_18670	COG2213	PTS system mannitol-specific
GTF72_18670	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTF72_18680	COG3722	fumarate hydratase activity
GTF72_18685	COG0673	inositol 2-dehydrogenase activity
GTF72_18715	COG2910	NAD(P)H-binding
GTF72_18725	COG0840	transmembrane signaling receptor activity
GTF72_18730	COG4221	oxidoreductase activity
GTF72_18740	COG1901	pseudouridine methyltransferase
GTF72_18755	COG0531	amino acid
GTF72_18760	COG1982	Orn Lys Arg decarboxylase major
GTF72_18790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GTF72_18815	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GTF72_18855	COG0745	RESPONSE REGULATOR receiver
GTF72_18880	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GTF72_18885	COG0840	transmembrane signaling receptor activity
GTF72_18890	COG0835	chemotaxis
GTF72_18895	COG0835	chemotaxis
GTF72_18900	COG2198	Histidine kinase
GTF72_18900	COG0643	Histidine kinase
GTF72_18920	COG0601	transmembrane transport
GTF72_18925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTF72_18935	COG2194	sulfuric ester hydrolase activity
GTF72_18940	COG0642	Histidine kinase
GTF72_18945	COG0745	RESPONSE REGULATOR receiver
GTF72_18980	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine