locus-tag	class	description
HND97_00020	COG0347	Belongs to the P(II) protein family
HND97_00050	COG0587	DNA-directed DNA polymerase activity
HND97_00105	COG0750	zinc metalloprotease
HND97_00110	COG0750	zinc metalloprotease
HND97_00225	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HND97_00715	COG0730	response to heat
HND97_00765	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HND97_00865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HND97_00870	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HND97_00875	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HND97_00880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HND97_01360	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HND97_01445	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HND97_01475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HND97_01525	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HND97_01600	COG2895	sulfate adenylyltransferase (ATP) activity
HND97_01625	COG0513	Belongs to the DEAD box helicase family
HND97_01670	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HND97_01675	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HND97_01680	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HND97_01685	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HND97_01700	COG1841	ribosomal large subunit assembly
HND97_01740	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HND97_01745	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HND97_01750	COG0255	Belongs to the universal ribosomal protein uL29 family
HND97_01765	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HND97_01770	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HND97_01845	COG0475	glutathione-regulated potassium exporter activity
HND97_01845	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HND97_02085	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HND97_02160	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HND97_02195	COG0254	rRNA binding
HND97_02340	COG0194	GDP metabolic process
HND97_02370	COG0745	RESPONSE REGULATOR receiver
HND97_02375	COG0745	RESPONSE REGULATOR receiver
HND97_02440	COG1040	competence protein
HND97_02955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HND97_03245	COG0606	chelatase, subunit chli
HND97_03370	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HND97_03435	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HND97_03470	COG2814	Major facilitator Superfamily
HND97_03475	COG2814	Major facilitator Superfamily
HND97_03480	COG2814	Major facilitator Superfamily
HND97_03740	COG0339	signal peptide processing
HND97_03885	COG2003	Belongs to the UPF0758 family
HND97_03955	COG0840	transmembrane signaling receptor activity
HND97_03965	COG2003	Belongs to the UPF0758 family
HND97_03975	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HND97_04115	COG0463	Glycosyl transferase, family 2
HND97_04165	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HND97_04220	COG0776	regulation of translation
HND97_04335	COG0511	ligase activity, forming carbon-carbon bonds
HND97_04360	COG2814	Major facilitator Superfamily
HND97_04400	COG3118	belongs to the thioredoxin family
HND97_04680	COG1923	regulation of RNA biosynthetic process
HND97_04770	COG0360	Binds together with S18 to 16S ribosomal RNA
HND97_04780	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HND97_04825	COG0735	belongs to the Fur family
HND97_05150	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HND97_05160	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HND97_05340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HND97_05355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HND97_05490	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HND97_05500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HND97_05605	COG0527	aspartate kinase activity
HND97_05785	COG2823	Periplasmic or secreted lipoprotein
HND97_06000	COG0316	Belongs to the HesB IscA family
HND97_06020	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HND97_06025	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HND97_06105	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HND97_06270	COG0640	Transcriptional regulator
HND97_06275	COG0268	Binds directly to 16S ribosomal RNA
HND97_06390	COG5001	Diguanylate cyclase
HND97_06555	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HND97_06600	COG0822	iron-sulfur transferase activity
HND97_06620	COG0633	Ferredoxin
HND97_06805	COG3630	sodium ion export across plasma membrane
HND97_06945	COG2914	Belongs to the UPF0125 (RnfH) family
HND97_07020	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HND97_07020	COG0047	phosphoribosylformylglycinamidine synthase activity
HND97_07065	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HND97_07120	COG1722	exodeoxyribonuclease VII activity
HND97_07250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HND97_07290	COG0438	transferase activity, transferring glycosyl groups
HND97_07405	COG2921	Belongs to the UPF0250 family
HND97_07435	COG0799	negative regulation of ribosome biogenesis
HND97_07495	COG2190	(PTS) system
HND97_07895	COG2832	Protein of unknown function (DUF454)
HND97_08125	COG0280	phosphate acetyltransferase
HND97_08125	COG0857	belongs to the CobB CobQ family
HND97_08150	COG4120	Belongs to the binding-protein-dependent transport system permease family
HND97_08260	COG2268	Band 7 protein
HND97_08350	COG1278	Cold shock
HND97_08560	COG2949	membrane
HND97_08835	COG4139	cobalamin transport
HND97_09430	COG0670	Belongs to the BI1 family
HND97_09435	COG0670	Belongs to the BI1 family
HND97_09470	COG0602	queuosine metabolic process
HND97_09700	COG1177	transmembrane transport
HND97_09710	COG3842	ATPase activity
HND97_09715	COG3842	ATPase activity
HND97_09830	COG3064	Membrane
HND97_09830	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
HND97_09830	COG1073	alpha beta
HND97_09835	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
HND97_09835	COG3064	Membrane
HND97_09835	COG1073	alpha beta
HND97_09840	COG1073	alpha beta
HND97_09840	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
HND97_09840	COG3064	Membrane
HND97_09860	COG3120	sequence-specific DNA binding
HND97_10280	COG0577	efflux transmembrane transporter activity
HND97_10280	COG1136	(ABC) transporter
HND97_10760	COG4934	collagen metabolic process
HND97_10765	COG4934	collagen metabolic process
HND97_10785	COG2205	protein histidine kinase activity
HND97_10785	COG2198	Histidine kinase
HND97_10785	COG0784	Response regulator, receiver
HND97_10785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HND97_10840	COG3313	Fe-S protein
HND97_10885	COG0626	cystathionine gamma-synthase activity
HND97_10895	COG0626	cystathionine gamma-synthase activity
HND97_11300	COG3311	Transcriptional regulator
HND97_11360	COG0840	transmembrane signaling receptor activity
HND97_11440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HND97_11565	COG2207	Transcriptional regulator
HND97_11565	COG1917	Cupin 2, conserved barrel domain protein
HND97_11930	COG3790	cyd operon protein YbgE
HND97_11935	COG4890	Cyd operon protein YbgT
HND97_11950	COG1271	oxidase subunit
HND97_12110	COG2835	tetraacyldisaccharide 4'-kinase activity
HND97_12225	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HND97_12230	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HND97_12235	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HND97_12240	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HND97_12245	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HND97_12250	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HND97_12270	COG0686	Belongs to the AlaDH PNT family
HND97_12480	COG0243	molybdopterin cofactor binding
HND97_12485	COG0243	molybdopterin cofactor binding
HND97_12490	COG0243	molybdopterin cofactor binding
HND97_12790	COG0733	neurotransmitter:sodium symporter activity
HND97_12840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HND97_12865	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HND97_12930	COG3082	Protein of unknown function (DUF1414)
HND97_13130	COG1918	ferrous iron import across plasma membrane
HND97_13260	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HND97_13265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HND97_13310	COG2840	Smr protein MutS2
HND97_13435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HND97_13930	COG0347	Belongs to the P(II) protein family
HND97_13980	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HND97_14005	COG0750	zinc metalloprotease
HND97_14045	COG0024	Methionine aminopeptidase
HND97_14050	COG0024	Methionine aminopeptidase
HND97_14425	COG0840	transmembrane signaling receptor activity
HND97_14650	COG0835	chemotaxis
HND97_14665	COG0745	RESPONSE REGULATOR receiver
HND97_15350	COG1129	ABC transporter
HND97_15355	COG1129	ABC transporter
HND97_15360	COG1129	ABC transporter
HND97_15365	COG1129	ABC transporter
HND97_15370	COG1129	ABC transporter
HND97_15475	COG2212	antiporter activity
HND97_15510	COG2111	Na H antiporter
HND97_15510	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HND97_15655	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HND97_15655	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HND97_15660	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HND97_15660	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HND97_16095	COG0509	glycine decarboxylation via glycine cleavage system
HND97_16115	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HND97_16120	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HND97_16140	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HND97_16145	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HND97_16215	COG3040	lipid binding
HND97_16220	COG3040	lipid binding
HND97_16540	COG3040	lipid binding
HND97_16545	COG3040	lipid binding
HND97_16780	COG0384	phenazine biosynthesis protein PhzF
HND97_17195	COG0784	Response regulator, receiver
HND97_17195	COG2205	protein histidine kinase activity
HND97_17240	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HND97_17240	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HND97_17240	COG1013	pyruvate-flavodoxin oxidoreductase activity
HND97_17240	COG0674	pyruvate-flavodoxin oxidoreductase activity
HND97_17260	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HND97_17260	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HND97_17260	COG1013	pyruvate-flavodoxin oxidoreductase activity
HND97_17260	COG0674	pyruvate-flavodoxin oxidoreductase activity
HND97_17265	COG0674	pyruvate-flavodoxin oxidoreductase activity
HND97_17265	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HND97_17265	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HND97_17265	COG1013	pyruvate-flavodoxin oxidoreductase activity
HND97_17550	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HND97_17720	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HND97_17725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HND97_17730	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HND97_17735	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HND97_18030	COG2197	response regulator
HND97_18675	COG0662	Cupin 2, conserved barrel domain protein
HND97_18860	COG0366	Alpha amylase catalytic
HND97_18905	COG3047	cAMP biosynthetic process
HND97_19025	COG0363	glucosamine-6-phosphate deaminase activity
HND97_19085	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HND97_19190	COG1278	Cold shock
HND97_19255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HND97_19280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HND97_19290	COG1846	Transcriptional regulator
HND97_19565	COG0700	Nucleoside recognition