locus-tag	class	description
ASZ81_00001	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ASZ81_00002	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ASZ81_00003	COG0706	membrane insertase activity
ASZ81_00004	COG0594	ribonuclease P activity
ASZ81_00005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ASZ81_00006	COG1126	abc transporter atp-binding protein
ASZ81_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASZ81_00011	COG0592	DNA-directed DNA polymerase activity
ASZ81_00012	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ASZ81_00013	COG0187	DNA topoisomerase II activity
ASZ81_00016	COG0071	Belongs to the small heat shock protein (HSP20) family
ASZ81_00017	COG3977	Valine--pyruvate aminotransferase
ASZ81_00018	COG0751	glycine-tRNA ligase activity
ASZ81_00019	COG0752	glycyl-tRNA synthetase alpha subunit
ASZ81_00020	COG2119	membrane
ASZ81_00022	COG0425	Belongs to the sulfur carrier protein TusA family
ASZ81_00024	COG0604	alcohol dehydrogenase
ASZ81_00026	COG0129	dihydroxy-acid dehydratase activity
ASZ81_00027	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASZ81_00030	COG0606	chelatase, subunit chli
ASZ81_00031	COG0204	Acyl-transferase
ASZ81_00032	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASZ81_00033	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ASZ81_00035	COG3084	Protein conserved in bacteria
ASZ81_00037	COG4326	sporulation control protein
ASZ81_00038	COG1272	protein, Hemolysin III
ASZ81_00040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASZ81_00041	COG0569	domain protein
ASZ81_00042	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ASZ81_00042	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASZ81_00043	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ASZ81_00044	COG0242	peptide deformylase activity
ASZ81_00045	COG1652	LysM domain
ASZ81_00046	COG0758	DNA mediated transformation
ASZ81_00047	COG2922	Belongs to the Smg family
ASZ81_00048	COG0551	DNA topoisomerase type I activity
ASZ81_00049	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ASZ81_00050	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ASZ81_00051	COG0009	L-threonylcarbamoyladenylate synthase
ASZ81_00052	COG0408	coproporphyrinogen oxidase activity
ASZ81_00053	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASZ81_00055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ASZ81_00063	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASZ81_00064	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ASZ81_00066	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ASZ81_00067	COG2104	thiamine diphosphate biosynthetic process
ASZ81_00068	COG2022	thiamine diphosphate biosynthetic process
ASZ81_00069	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ASZ81_00070	COG0006	proline dipeptidase activity
ASZ81_00070	COG0006	proline dipeptidase activity
ASZ81_00074	COG1522	sequence-specific DNA binding
ASZ81_00075	COG5002	protein histidine kinase activity
ASZ81_00075	COG5001	Diguanylate cyclase
ASZ81_00076	COG0742	ribosomal rna small subunit methyltransferase
ASZ81_00078	COG0697	spore germination
ASZ81_00079	COG0589	response to stress
ASZ81_00080	COG1528	Iron-storage protein
ASZ81_00082	COG2081	HI0933 family
ASZ81_00084	COG1322	Protein conserved in bacteria
ASZ81_00085	COG2226	methyltransferase
ASZ81_00087	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASZ81_00088	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASZ81_00089	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASZ81_00090	COG0805	protein transport
ASZ81_00091	COG1858	cytochrome C peroxidase
ASZ81_00092	COG0534	Mate efflux family protein
ASZ81_00094	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ASZ81_00095	COG2937	Belongs to the GPAT DAPAT family
ASZ81_00096	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ASZ81_00097	COG3161	chorismate lyase activity
ASZ81_00098	COG1580	Controls the rotational direction of flagella during chemotaxis
ASZ81_00099	COG0840	transmembrane signaling receptor activity
ASZ81_00101	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASZ81_00103	COG0084	hydrolase, TatD family'
ASZ81_00108	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASZ81_00108	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASZ81_00110	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ASZ81_00113	COG3078	GTPase activator activity
ASZ81_00115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASZ81_00116	COG3071	HemY protein
ASZ81_00117	COG2959	enzyme of heme biosynthesis
ASZ81_00118	COG1587	Uroporphyrinogen-III synthase
ASZ81_00119	COG0181	hydroxymethylbilane synthase activity
ASZ81_00120	COG3072	Adenylate cyclase
ASZ81_00121	COG1965	Belongs to the frataxin family
ASZ81_00123	COG0019	diaminopimelate decarboxylase activity
ASZ81_00124	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ASZ81_00126	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ASZ81_00127	COG1011	Hydrolase
ASZ81_00128	COG2199	diguanylate cyclase activity
ASZ81_00128	COG2200	EAL domain
ASZ81_00128	COG3287	FIST C domain
ASZ81_00131	COG0561	phosphatase activity
ASZ81_00132	COG2267	carboxylic ester hydrolase activity
ASZ81_00133	COG1280	lysine exporter protein (LysE YggA)
ASZ81_00134	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ASZ81_00136	COG0783	Belongs to the Dps family
ASZ81_00142	COG0742	ribosomal rna small subunit methyltransferase
ASZ81_00143	COG0552	protein localization to endoplasmic reticulum
ASZ81_00144	COG2884	Cell division ATP-binding protein ftsE
ASZ81_00145	COG2177	Part of the ABC transporter FtsEX involved in
ASZ81_00146	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASZ81_00147	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASZ81_00150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASZ81_00151	COG4206	TonB-dependent receptor
ASZ81_00152	COG1404	Belongs to the peptidase S8 family
ASZ81_00153	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ASZ81_00161	COG0583	DNA-binding transcription factor activity
ASZ81_00162	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ASZ81_00163	COG2960	long-chain fatty acid transporting porin activity
ASZ81_00164	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASZ81_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ81_00166	COG1309	transcriptional regulator
ASZ81_00176	COG0747	negative chemotaxis
ASZ81_00178	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASZ81_00180	COG2131	deaminase
ASZ81_00189	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASZ81_00190	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ASZ81_00192	COG0210	DNA helicase
ASZ81_00193	COG1280	lysine exporter protein (LysE YggA)
ASZ81_00196	COG2962	Rard protein
ASZ81_00198	COG0514	ATP-dependent DNA helicase (RecQ)
ASZ81_00201	COG1132	(ABC) transporter
ASZ81_00202	COG4774	siderophore transport
ASZ81_00203	COG1120	ATPase activity
ASZ81_00207	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ASZ81_00208	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ81_00208	COG1263	PTS System
ASZ81_00210	COG1561	YicC-like family, N-terminal region
ASZ81_00211	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ASZ81_00212	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ASZ81_00213	COG1560	Kdo2-lipid A biosynthetic process
ASZ81_00214	COG1560	Kdo2-lipid A biosynthetic process
ASZ81_00215	COG1309	transcriptional regulator
ASZ81_00217	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ASZ81_00221	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASZ81_00222	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ASZ81_00224	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ASZ81_00225	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ASZ81_00226	COG0859	PFAM glycosyl transferase family 9
ASZ81_00227	COG0463	Glycosyl transferase, family 2
ASZ81_00228	COG0859	PFAM glycosyl transferase family 9
ASZ81_00229	COG3642	lipopolysaccharide core region biosynthetic process
ASZ81_00235	COG1519	Transferase
ASZ81_00242	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASZ81_00243	COG0662	Cupin 2, conserved barrel domain protein
ASZ81_00243	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ASZ81_00244	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASZ81_00245	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ASZ81_00251	COG0318	PFAM AMP-dependent synthetase and ligase
ASZ81_00252	COG1454	alcohol dehydrogenase
ASZ81_00252	COG1012	belongs to the aldehyde dehydrogenase family
ASZ81_00255	COG5433	transposase activity
ASZ81_00256	COG5433	transposase activity
ASZ81_00261	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASZ81_00263	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ASZ81_00264	COG0668	transmembrane transport
ASZ81_00265	COG1573	uracil-dna glycosylase
ASZ81_00267	COG3068	Protein conserved in bacteria
ASZ81_00269	COG1940	carbohydrate kinase activity
ASZ81_00270	COG1253	flavin adenine dinucleotide binding
ASZ81_00271	COG0776	regulation of translation
ASZ81_00273	COG0151	Belongs to the GarS family
ASZ81_00274	COG0138	bifunctional purine biosynthesis protein purh
ASZ81_00276	COG0789	Transcriptional regulator
ASZ81_00277	COG3710	Transcriptional regulator
ASZ81_00279	COG0531	amino acid
ASZ81_00280	COG1982	Orn Lys Arg decarboxylase major
ASZ81_00281	COG0840	transmembrane signaling receptor activity
ASZ81_00285	COG0800	Aldolase
ASZ81_00287	COG3265	gluconokinase activity
ASZ81_00288	COG0129	dihydroxy-acid dehydratase activity
ASZ81_00289	COG1609	Transcriptional regulator
ASZ81_00290	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ASZ81_00291	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASZ81_00292	COG2264	protein methyltransferase activity
ASZ81_00293	COG0439	Biotin carboxylase
ASZ81_00294	COG0511	ligase activity, forming carbon-carbon bonds
ASZ81_00295	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ASZ81_00296	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASZ81_00299	COG2814	Major facilitator Superfamily
ASZ81_00300	COG2205	protein histidine kinase activity
ASZ81_00300	COG0784	Response regulator, receiver
ASZ81_00301	COG0248	Ppx GppA phosphatase
ASZ81_00302	COG0513	Belongs to the DEAD box helicase family
ASZ81_00303	COG3118	belongs to the thioredoxin family
ASZ81_00304	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ASZ81_00306	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASZ81_00315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASZ81_00317	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ASZ81_00319	COG1072	(Pantothenic acid kinase))
ASZ81_00324	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASZ81_00325	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASZ81_00326	COG0250	Participates in transcription elongation, termination and antitermination
ASZ81_00327	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ASZ81_00328	COG0081	regulation of translation
ASZ81_00329	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ASZ81_00330	COG0222	ribosome binding
ASZ81_00331	COG0085	RNA polymerase activity
ASZ81_00332	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ASZ81_00333	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
ASZ81_00334	COG2816	NAD+ diphosphatase activity
ASZ81_00335	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ASZ81_00338	COG4942	peptidase
ASZ81_00339	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ASZ81_00341	COG0471	metal ion transport
ASZ81_00342	COG0688	phosphatidylethanolamine metabolic process
ASZ81_00343	COG1162	GTPase activity
ASZ81_00344	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ASZ81_00354	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ASZ81_00355	COG0802	atpase or kinase
ASZ81_00357	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ASZ81_00358	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ASZ81_00359	COG1923	regulation of RNA biosynthetic process
ASZ81_00360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ASZ81_00361	COG0330	HflC and HflK could
ASZ81_00362	COG0330	HflC and HflK could
ASZ81_00363	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ASZ81_00364	COG2900	Belongs to the SlyX family
ASZ81_00366	COG0545	Peptidyl-prolyl cis-trans isomerase
ASZ81_00367	COG2964	Protein conserved in bacteria
ASZ81_00368	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ASZ81_00369	COG2923	Belongs to the DsrF TusC family
ASZ81_00371	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ASZ81_00372	COG0049	tRNA binding
ASZ81_00373	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASZ81_00374	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASZ81_00375	COG2906	2 iron, 2 sulfur cluster binding
ASZ81_00377	COG0360	Binds together with S18 to 16S ribosomal RNA
ASZ81_00378	COG2965	DNA replication, synthesis of RNA primer
ASZ81_00379	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ASZ81_00380	COG0359	binds to the 23S rRNA
ASZ81_00382	COG0305	Participates in initiation and elongation during chromosome replication
ASZ81_00383	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASZ81_00384	COG0432	Pfam Uncharacterised protein family UPF0047
ASZ81_00385	COG0166	Belongs to the GPI family
ASZ81_00388	COG0735	belongs to the Fur family
ASZ81_00389	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASZ81_00395	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ASZ81_00396	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASZ81_00397	COG0175	sulfate reduction
ASZ81_00411	COG0646	methionine synthase
ASZ81_00411	COG1410	methionine synthase
ASZ81_00412	COG0527	aspartate kinase activity
ASZ81_00413	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ASZ81_00415	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ASZ81_00418	COG0629	single-stranded DNA binding
ASZ81_00419	COG2199	diguanylate cyclase activity
ASZ81_00419	COG2200	EAL domain
ASZ81_00424	COG3267	Type II secretory pathway component ExeA
ASZ81_00424	COG3409	Peptidoglycan-binding domain 1 protein
ASZ81_00426	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASZ81_00427	COG1459	type II secretion system
ASZ81_00436	COG1077	Cell shape determining protein MreB Mrl
ASZ81_00437	COG1792	Involved in formation and maintenance of cell shape
ASZ81_00438	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ASZ81_00439	COG0424	maF-like protein
ASZ81_00440	COG1530	ribonuclease E activity
ASZ81_00441	COG3164	Protein of unknown function
ASZ81_00442	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASZ81_00443	COG0312	modulator of DNA gyrase
ASZ81_00444	COG2235	arginine
ASZ81_00448	COG0589	response to stress
ASZ81_00451	COG1438	arginine binding
ASZ81_00452	COG0039	L-malate dehydrogenase activity
ASZ81_00453	COG0531	amino acid
ASZ81_00454	COG0142	geranyltranstransferase activity
ASZ81_00455	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ASZ81_00456	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ASZ81_00457	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ASZ81_00458	COG2966	Psort location CytoplasmicMembrane, score
ASZ81_00459	COG3610	response to peptide
ASZ81_00461	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASZ81_00462	COG2967	ApaG domain
ASZ81_00463	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ASZ81_00464	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ASZ81_00465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASZ81_00466	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ASZ81_00467	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASZ81_00478	COG0741	lytic transglycosylase activity
ASZ81_00479	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ASZ81_00480	COG1194	a g-specific adenine glycosylase
ASZ81_00482	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASZ81_00483	COG2066	Belongs to the glutaminase family
ASZ81_00484	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASZ81_00485	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ASZ81_00487	COG1872	DUF167
ASZ81_00488	COG0762	integral membrane protein
ASZ81_00489	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ASZ81_00490	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ASZ81_00494	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASZ81_00495	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ASZ81_00496	COG1678	Uncharacterized ACR, COG1678
ASZ81_00497	COG0189	ligase activity
ASZ81_00498	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASZ81_00499	COG2356	endonuclease I
ASZ81_00500	COG3091	SprT-like family
ASZ81_00501	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ASZ81_00503	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASZ81_00504	COG0583	DNA-binding transcription factor activity
ASZ81_00505	COG4771	TonB-dependent receptor
ASZ81_00506	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASZ81_00507	COG0126	phosphoglycerate kinase activity
ASZ81_00508	COG0191	fructose-bisphosphate aldolase activity
ASZ81_00509	COG0668	transmembrane transport
ASZ81_00510	COG1279	arginine transmembrane transporter activity
ASZ81_00511	COG0583	DNA-binding transcription factor activity
ASZ81_00514	COG0469	pyruvate kinase activity
ASZ81_00515	COG1349	DNA-binding transcription factor activity
ASZ81_00516	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ASZ81_00517	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASZ81_00528	COG0328	RNA-DNA hybrid ribonuclease activity
ASZ81_00536	COG0739	heme binding
ASZ81_00543	COG2003	Belongs to the UPF0758 family
ASZ81_00545	COG0840	transmembrane signaling receptor activity
ASZ81_00546	COG2207	Transcriptional regulator
ASZ81_00547	COG0840	transmembrane signaling receptor activity
ASZ81_00548	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ASZ81_00549	COG0582	viral genome integration into host DNA
ASZ81_00551	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASZ81_00552	COG0358	DNA primase activity
ASZ81_00553	COG1610	YqeY-like protein
ASZ81_00554	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ASZ81_00556	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ASZ81_00558	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASZ81_00559	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ASZ81_00560	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ASZ81_00561	COG1968	undecaprenyl-diphosphatase activity
ASZ81_00562	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ASZ81_00563	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ASZ81_00564	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ASZ81_00565	COG0585	pseudouridine synthase activity
ASZ81_00566	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ASZ81_00567	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ASZ81_00568	COG4942	peptidase
ASZ81_00568	COG1388	LysM domain
ASZ81_00569	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASZ81_00570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ASZ81_00574	COG4208	sulfate ABC transporter
ASZ81_00575	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ASZ81_00577	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ASZ81_00578	COG2137	regulation of response to DNA damage stimulus
ASZ81_00579	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ASZ81_00581	COG0527	aspartate kinase activity
ASZ81_00582	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ASZ81_00591	COG3630	sodium ion export across plasma membrane
ASZ81_00592	COG0511	ligase activity, forming carbon-carbon bonds
ASZ81_00592	COG5016	pyruvate
ASZ81_00593	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ASZ81_00595	COG1238	metal cluster binding
ASZ81_00596	COG0612	Peptidase, M16
ASZ81_00597	COG2918	glutathione biosynthetic process
ASZ81_00598	COG1854	S-ribosylhomocysteine lyase activity
ASZ81_00599	COG4536	flavin adenine dinucleotide binding
ASZ81_00600	COG4137	Cytochrome C assembly protein
ASZ81_00601	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ASZ81_00602	COG0228	four-way junction DNA binding
ASZ81_00603	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ASZ81_00604	COG0336	Belongs to the RNA methyltransferase TrmD family
ASZ81_00605	COG0335	large ribosomal subunit rRNA binding
ASZ81_00606	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASZ81_00607	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASZ81_00609	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ASZ81_00610	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ASZ81_00611	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ASZ81_00612	COG0723	plastoquinol--plastocyanin reductase activity
ASZ81_00613	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ASZ81_00614	COG2857	Cytochrome c1
ASZ81_00615	COG0625	glutathione transferase activity
ASZ81_00616	COG2969	positive regulation of protein catabolic process
ASZ81_00617	COG2823	Periplasmic or secreted lipoprotein
ASZ81_00618	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ASZ81_00619	COG0792	nuclease activity
ASZ81_00620	COG3107	peptidoglycan biosynthetic process
ASZ81_00621	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ASZ81_00624	COG0288	reversible hydration of carbon dioxide
ASZ81_00625	COG0659	secondary active sulfate transmembrane transporter activity
ASZ81_00626	COG1131	(ABC) transporter
ASZ81_00627	COG0842	Transport permease protein
ASZ81_00628	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ASZ81_00629	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ASZ81_00630	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ASZ81_00632	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASZ81_00633	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ASZ81_00634	COG1489	DNA binding
ASZ81_00636	COG1643	Atp-dependent helicase
ASZ81_00637	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASZ81_00638	COG1752	Esterase of the alpha-beta hydrolase superfamily
ASZ81_00639	COG1049	propionate catabolic process, 2-methylcitrate cycle
ASZ81_00640	COG3112	Uncharacterised protein family (UPF0231)
ASZ81_00641	COG0347	Belongs to the P(II) protein family
ASZ81_00642	COG0004	ammonium transporteR
ASZ81_00643	COG1840	ABC-type Fe3 transport system, periplasmic component
ASZ81_00645	COG3842	ATPase activity
ASZ81_00649	COG2971	BadF BadG BcrA BcrD
ASZ81_00651	COG4608	Belongs to the ABC transporter superfamily
ASZ81_00652	COG0444	Belongs to the ABC transporter superfamily
ASZ81_00653	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASZ81_00654	COG0601	transmembrane transport
ASZ81_00655	COG0747	negative chemotaxis
ASZ81_00657	COG2813	Specifically methylates the guanine in position
ASZ81_00658	COG0628	permease
ASZ81_00659	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ASZ81_00661	COG0316	Belongs to the HesB IscA family
ASZ81_00664	COG0739	heme binding
ASZ81_00665	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASZ81_00666	COG2027	D-alanyl-D-alanine carboxypeptidase
ASZ81_00667	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASZ81_00668	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASZ81_00669	COG1534	Rna-binding protein
ASZ81_00670	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ASZ81_00671	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASZ81_00672	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ASZ81_00673	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASZ81_00674	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASZ81_00677	COG0779	Required for maturation of 30S ribosomal subunits
ASZ81_00678	COG0195	Participates in both transcription termination and antitermination
ASZ81_00679	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ASZ81_00680	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASZ81_00681	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ASZ81_00682	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ASZ81_00683	COG1185	polyribonucleotide nucleotidyltransferase activity
ASZ81_00684	COG4785	May be involved in cell division
ASZ81_00691	COG3153	acetyltransferase
ASZ81_00695	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ASZ81_00696	COG0513	Belongs to the DEAD box helicase family
ASZ81_00697	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ASZ81_00699	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ASZ81_00700	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASZ81_00701	COG2204	response regulator
ASZ81_00705	COG0667	Aldo Keto reductase
ASZ81_00706	COG3066	DNA modification
ASZ81_00709	COG0494	nUDIX hydrolase
ASZ81_00710	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ASZ81_00711	COG0730	response to heat
ASZ81_00712	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ASZ81_00713	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ASZ81_00714	COG1283	sodium-dependent phosphate transmembrane transporter activity
ASZ81_00715	COG0583	DNA-binding transcription factor activity
ASZ81_00716	COG0640	Transcriptional regulator
ASZ81_00717	COG0268	Binds directly to 16S ribosomal RNA
ASZ81_00718	COG0728	peptidoglycan biosynthetic process
ASZ81_00719	COG0196	riboflavin kinase activity
ASZ81_00720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ASZ81_00721	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ASZ81_00722	COG1047	Peptidyl-prolyl cis-trans
ASZ81_00723	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ASZ81_00724	COG1966	Carbon starvation protein
ASZ81_00727	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ASZ81_00728	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ASZ81_00729	COG1472	Belongs to the glycosyl hydrolase 3 family
ASZ81_00730	COG3279	Response regulator of the LytR AlgR family
ASZ81_00731	COG3275	phosphorelay sensor kinase activity
ASZ81_00732	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASZ81_00733	COG0287	Prephenate dehydrogenase
ASZ81_00733	COG1605	Chorismate mutase
ASZ81_00735	COG0488	(ABC) transporter
ASZ81_00737	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
ASZ81_00738	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
ASZ81_00739	COG5001	Diguanylate cyclase
ASZ81_00740	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASZ81_00741	COG1605	Chorismate mutase
ASZ81_00741	COG0077	Prephenate dehydratase
ASZ81_00742	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ASZ81_00744	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASZ81_00745	COG0564	pseudouridine synthase activity
ASZ81_00747	COG0542	response to heat
ASZ81_00755	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASZ81_00757	COG2974	May be involved in recombination
ASZ81_00758	COG0745	RESPONSE REGULATOR receiver
ASZ81_00759	COG5002	protein histidine kinase activity
ASZ81_00761	COG0248	Ppx GppA phosphatase
ASZ81_00762	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ASZ81_00764	COG0581	inorganic phosphate transmembrane transporter activity
ASZ81_00765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASZ81_00768	COG3142	Participates in the control of copper homeostasis
ASZ81_00769	COG0450	alkyl hydroperoxide reductase
ASZ81_00770	COG0583	DNA-binding transcription factor activity
ASZ81_00771	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ASZ81_00773	COG0517	IMP dehydrogenase activity
ASZ81_00774	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ASZ81_00775	COG0343	queuine tRNA-ribosyltransferase activity
ASZ81_00776	COG1862	Preprotein translocase
ASZ81_00777	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASZ81_00778	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASZ81_00779	COG0483	inositol monophosphate 1-phosphatase activity
ASZ81_00781	COG1959	2 iron, 2 sulfur cluster binding
ASZ81_00782	COG1104	cysteine desulfurase activity
ASZ81_00783	COG0822	iron-sulfur transferase activity
ASZ81_00784	COG0316	Belongs to the HesB IscA family
ASZ81_00785	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASZ81_00786	COG0443	Heat shock 70 kDa protein
ASZ81_00787	COG0633	Ferredoxin
ASZ81_00788	COG2975	iron-sulfur cluster assembly
ASZ81_00789	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASZ81_00790	COG0105	UTP biosynthetic process
ASZ81_00791	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ASZ81_00793	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ASZ81_00794	COG0124	histidyl-tRNA synthetase
ASZ81_00795	COG2976	Protein conserved in bacteria
ASZ81_00796	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASZ81_00797	COG1160	GTP binding
ASZ81_00800	COG1570	exodeoxyribonuclease VII activity
ASZ81_00801	COG0516	GMP reductase activity
ASZ81_00801	COG0517	IMP dehydrogenase activity
ASZ81_00802	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASZ81_00802	COG0519	Catalyzes the synthesis of GMP from XMP
ASZ81_00804	COG1584	GPR1 FUN34 yaaH family protein
ASZ81_00805	COG3433	isochorismatase activity
ASZ81_00805	COG1535	isochorismatase
ASZ81_00806	COG1021	2,3-dihydroxybenzoate-AMP ligase
ASZ81_00807	COG1169	isochorismate synthase
ASZ81_00808	COG1028	Short-chain dehydrogenase reductase Sdr
ASZ81_00810	COG4592	Periplasmic binding protein
ASZ81_00811	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASZ81_00812	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASZ81_00813	COG1120	ATPase activity
ASZ81_00815	COG0583	DNA-binding transcription factor activity
ASZ81_00816	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ASZ81_00817	COG1115	amino acid carrier protein
ASZ81_00818	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASZ81_00819	COG0583	DNA-binding transcription factor activity
ASZ81_00822	COG4565	transcriptional regulatory protein
ASZ81_00824	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ASZ81_00825	COG5016	pyruvate
ASZ81_00825	COG0511	ligase activity, forming carbon-carbon bonds
ASZ81_00826	COG3630	sodium ion export across plasma membrane
ASZ81_00828	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ASZ81_00829	COG3052	prosthetic group binding
ASZ81_00830	COG2301	Belongs to the HpcH HpaI aldolase family
ASZ81_00831	COG3051	citrate lyase alpha subunit
ASZ81_00832	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
ASZ81_00833	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ASZ81_00835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASZ81_00836	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ASZ81_00837	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ASZ81_00849	COG1012	belongs to the aldehyde dehydrogenase family
ASZ81_00853	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ASZ81_00854	COG0840	transmembrane signaling receptor activity
ASZ81_00855	COG3710	Transcriptional regulator
ASZ81_00856	COG3710	Transcriptional regulator
ASZ81_00858	COG2165	general secretion pathway protein
ASZ81_00861	COG4796	Type ii and iii secretion system protein
ASZ81_00865	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASZ81_00866	COG1459	type II secretion system
ASZ81_00868	COG2207	Transcriptional regulator
ASZ81_00869	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ASZ81_00870	COG0840	transmembrane signaling receptor activity
ASZ81_00872	COG0739	heme binding
ASZ81_00874	COG3064	Membrane
ASZ81_00876	COG0582	viral genome integration into host DNA
ASZ81_00878	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ASZ81_00879	COG2867	negative regulation of translational initiation
ASZ81_00880	COG2914	Belongs to the UPF0125 (RnfH) family
ASZ81_00881	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASZ81_00882	COG0497	DNA recombination
ASZ81_00883	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ASZ81_00884	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ASZ81_00886	COG0443	Heat shock 70 kDa protein
ASZ81_00887	COG0484	heat shock protein binding
ASZ81_00893	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ASZ81_00894	COG0590	tRNA wobble adenosine to inosine editing
ASZ81_00896	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ASZ81_00899	COG0047	phosphoribosylformylglycinamidine synthase activity
ASZ81_00899	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASZ81_00903	COG0442	prolyl-tRNA aminoacylation
ASZ81_00904	COG1720	tRNA m6t6A37 methyltransferase activity
ASZ81_00905	COG0254	rRNA binding
ASZ81_00906	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ASZ81_00907	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ASZ81_00908	COG1671	Belongs to the UPF0178 family
ASZ81_00910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ81_00913	COG3098	single-species biofilm formation
ASZ81_00914	COG0564	pseudouridine synthase activity
ASZ81_00915	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ASZ81_00916	COG0142	geranyltranstransferase activity
ASZ81_00917	COG1722	exodeoxyribonuclease VII activity
ASZ81_00918	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ASZ81_00920	COG0301	tRNA thio-modification
ASZ81_00920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASZ81_00921	COG0583	DNA-binding transcription factor activity
ASZ81_00922	COG2363	Small membrane protein
ASZ81_00923	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASZ81_00924	COG1611	Belongs to the LOG family
ASZ81_00925	COG3706	GGDEF domain
ASZ81_00927	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASZ81_00927	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASZ81_00929	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
ASZ81_00930	COG1464	Belongs to the NlpA lipoprotein family
ASZ81_00931	COG2011	ABC-type metal ion transport system permease component
ASZ81_00932	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASZ81_00933	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASZ81_00934	COG1609	Transcriptional regulator
ASZ81_00935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ81_00935	COG1263	PTS System
ASZ81_00936	COG0366	Alpha amylase catalytic
ASZ81_00942	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASZ81_00943	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASZ81_00944	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ASZ81_00945	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ASZ81_00946	COG0110	maltose O-acetyltransferase activity
ASZ81_00950	COG1045	serine acetyltransferase
ASZ81_00952	COG0438	transferase activity, transferring glycosyl groups
ASZ81_00954	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ASZ81_00960	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASZ81_00962	COG1596	polysaccharide export
ASZ81_00968	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASZ81_00970	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ASZ81_00971	COG0321	lipoyl(octanoyl) transferase activity
ASZ81_00972	COG2921	Belongs to the UPF0250 family
ASZ81_00973	COG1686	Belongs to the peptidase S11 family
ASZ81_00974	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ASZ81_00975	COG0772	Belongs to the SEDS family
ASZ81_00976	COG0768	penicillin binding
ASZ81_00977	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ASZ81_00978	COG0799	negative regulation of ribosome biogenesis
ASZ81_00979	COG1466	dna polymerase III delta subunit
ASZ81_00980	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ASZ81_00981	COG0495	leucyl-tRNA aminoacylation
ASZ81_00982	COG2888	peptidyl-tyrosine sulfation
ASZ81_00983	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ASZ81_00984	COG4535	Mg2 and Co2 transporter CorC
ASZ81_00985	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ASZ81_00986	COG1702	phosphate starvation-inducible protein PhoH
ASZ81_00987	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASZ81_00988	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASZ81_00989	COG2190	(PTS) system
ASZ81_00991	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ81_00992	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ASZ81_00993	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ASZ81_00994	COG3115	cell septum assembly
ASZ81_00995	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASZ81_00998	COG0789	Transcriptional regulator
ASZ81_00999	COG1585	Membrane protein implicated in regulation of membrane protease activity
ASZ81_01000	COG0330	HflC and HflK could
ASZ81_01001	COG3118	belongs to the thioredoxin family
ASZ81_01003	COG0300	oxidoreductase activity
ASZ81_01004	COG1090	epimerase
ASZ81_01005	COG0622	Phosphoesterase
ASZ81_01008	COG3710	Transcriptional regulator
ASZ81_01009	COG0326	Molecular chaperone. Has ATPase activity
ASZ81_01010	COG0563	adenylate kinase activity
ASZ81_01011	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ASZ81_01015	COG0367	asparagine synthase
ASZ81_01016	COG4651	solute:proton antiporter activity
ASZ81_01016	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASZ81_01017	COG1846	Transcriptional regulator
ASZ81_01017	COG1940	carbohydrate kinase activity
ASZ81_01018	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ASZ81_01019	COG2190	(PTS) system
ASZ81_01019	COG1263	PTS System
ASZ81_01019	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ81_01020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASZ81_01023	COG0101	tRNA pseudouridine synthase activity
ASZ81_01024	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ASZ81_01025	COG0285	dihydrofolate synthase activity
ASZ81_01026	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ASZ81_01027	COG1286	toxin biosynthetic process
ASZ81_01028	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ASZ81_01029	COG2056	Na+-H+ antiporter family
ASZ81_01030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASZ81_01034	COG0346	lactoylglutathione lyase activity
ASZ81_01035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ASZ81_01036	COG4660	Part of a membrane complex involved in electron transport
ASZ81_01037	COG4659	FMN binding
ASZ81_01038	COG4658	electron transport chain
ASZ81_01039	COG4656	Part of a membrane complex involved in electron transport
ASZ81_01040	COG2878	Part of a membrane complex involved in electron transport
ASZ81_01041	COG4657	Part of a membrane complex involved in electron transport
ASZ81_01043	COG0556	nucleotide-excision repair
ASZ81_01044	COG2204	response regulator
ASZ81_01045	COG2198	Histidine kinase
ASZ81_01046	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ASZ81_01047	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ASZ81_01048	COG0521	Mo-molybdopterin cofactor biosynthetic process
ASZ81_01049	COG0315	cyclic pyranopterin monophosphate synthase activity
ASZ81_01050	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ASZ81_01051	COG0314	molybdopterin synthase activity
ASZ81_01052	COG2199	diguanylate cyclase activity
ASZ81_01053	COG4109	DRTGG domain
ASZ81_01055	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ASZ81_01057	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASZ81_01057	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASZ81_01058	COG0489	protein tyrosine kinase activity
ASZ81_01059	COG0572	uridine kinase
ASZ81_01060	COG2982	Protein involved in outer membrane biogenesis
ASZ81_01061	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ASZ81_01062	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASZ81_01064	COG2067	long-chain fatty acid transport protein
ASZ81_01067	COG0183	Belongs to the thiolase family
ASZ81_01068	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASZ81_01068	COG1024	Enoyl-CoA hydratase
ASZ81_01069	COG0778	Nitroreductase
ASZ81_01070	COG0583	DNA-binding transcription factor activity
ASZ81_01071	COG0745	RESPONSE REGULATOR receiver
ASZ81_01074	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASZ81_01076	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ASZ81_01077	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ASZ81_01080	COG1028	Short-chain dehydrogenase reductase Sdr
ASZ81_01081	COG0616	signal peptide processing
ASZ81_01083	COG1522	sequence-specific DNA binding
ASZ81_01084	COG1946	Acyl-CoA thioesterase
ASZ81_01088	COG3706	GGDEF domain
ASZ81_01089	COG0640	Transcriptional regulator
ASZ81_01090	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASZ81_01096	COG1881	PFAM PEBP family protein
ASZ81_01100	COG0009	L-threonylcarbamoyladenylate synthase
ASZ81_01103	COG2201	protein-glutamate methylesterase activity
ASZ81_01105	COG5002	protein histidine kinase activity
ASZ81_01106	COG4191	Histidine kinase
ASZ81_01107	COG3300	MHYT domain
ASZ81_01107	COG5001	Diguanylate cyclase
ASZ81_01108	COG2204	response regulator
ASZ81_01112	COG0601	transmembrane transport
ASZ81_01113	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASZ81_01114	COG0444	Belongs to the ABC transporter superfamily
ASZ81_01115	COG4608	Belongs to the ABC transporter superfamily
ASZ81_01116	COG0435	Glutathione S-transferase
ASZ81_01117	COG0280	phosphate acetyltransferase
ASZ81_01117	COG0857	belongs to the CobB CobQ family
ASZ81_01118	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASZ81_01119	COG3092	negative regulation of chromosome organization
ASZ81_01120	COG4628	conserved protein (DUF2132)
ASZ81_01122	COG4120	Belongs to the binding-protein-dependent transport system permease family
ASZ81_01124	COG2199	diguanylate cyclase activity
ASZ81_01124	COG2203	Gaf domain
ASZ81_01125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASZ81_01127	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ASZ81_01128	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASZ81_01129	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ASZ81_01130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASZ81_01131	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ASZ81_01132	COG0156	8-amino-7-oxononanoate synthase activity
ASZ81_01133	COG2226	methyltransferase
ASZ81_01134	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ASZ81_01136	COG0501	Belongs to the peptidase M48B family
ASZ81_01138	COG0300	oxidoreductase activity
ASZ81_01141	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASZ81_01143	COG2268	Band 7 protein
ASZ81_01145	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASZ81_01146	COG2915	High frequency lysogenization protein hflD homolog
ASZ81_01147	COG0482	sulfurtransferase activity
ASZ81_01148	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASZ81_01149	COG2916	Histone family protein nucleoid-structuring protein H-NS
ASZ81_01150	COG1757	Na H antiporter
ASZ81_01151	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ASZ81_01152	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ASZ81_01153	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASZ81_01154	COG0131	Imidazoleglycerol-phosphate dehydratase
ASZ81_01154	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASZ81_01155	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ASZ81_01156	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ASZ81_01157	COG0107	imidazoleglycerol-phosphate synthase activity
ASZ81_01158	COG0140	phosphoribosyl-ATP diphosphatase activity
ASZ81_01158	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ASZ81_01159	COG1187	pseudouridine synthase activity
ASZ81_01161	COG1278	Cold shock
ASZ81_01162	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ASZ81_01163	COG0542	response to heat
ASZ81_01165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASZ81_01166	COG1012	belongs to the aldehyde dehydrogenase family
ASZ81_01166	COG1454	alcohol dehydrogenase
ASZ81_01167	COG1737	Transcriptional regulator
ASZ81_01168	COG0076	glutamate decarboxylase activity
ASZ81_01170	COG2431	L-lysine efflux transmembrane transporter activity
ASZ81_01172	COG3070	regulator of competence-specific genes
ASZ81_01175	COG3852	Histidine kinase
ASZ81_01177	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ASZ81_01180	COG4067	protein conserved in archaea
ASZ81_01180	COG0189	ligase activity
ASZ81_01181	COG0500	methyltransferase
ASZ81_01182	COG4106	trans-aconitate 2-methyltransferase activity
ASZ81_01183	COG1801	Protein of unknown function DUF72
ASZ81_01184	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ASZ81_01185	COG1435	thymidine kinase activity
ASZ81_01187	COG0159	tryptophan synthase activity
ASZ81_01188	COG0133	tryptophan synthase activity
ASZ81_01189	COG0135	phosphoribosylanthranilate isomerase activity
ASZ81_01189	COG0134	indole-3-glycerol-phosphate synthase activity
ASZ81_01190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASZ81_01191	COG0512	Glutamine amidotransferase of anthranilate synthase
ASZ81_01192	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASZ81_01194	COG0613	PHP domain protein
ASZ81_01195	COG0009	L-threonylcarbamoyladenylate synthase
ASZ81_01196	COG1187	pseudouridine synthase activity
ASZ81_01197	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ASZ81_01198	COG4988	ABC transporter
ASZ81_01199	COG0492	ferredoxin-NADP+ reductase activity
ASZ81_01201	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASZ81_01202	COG3706	GGDEF domain
ASZ81_01203	COG2949	membrane
ASZ81_01205	COG0281	malic enzyme
ASZ81_01207	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ASZ81_01211	COG2885	chlorophyll binding
ASZ81_01214	COG0247	lactate metabolic process
ASZ81_01214	COG0277	FAD linked oxidase domain protein
ASZ81_01218	COG2986	histidine ammonia-lyase
ASZ81_01219	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ASZ81_01220	COG0010	Belongs to the arginase family
ASZ81_01221	COG1228	amidohydrolase
ASZ81_01225	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASZ81_01227	COG5001	Diguanylate cyclase
ASZ81_01228	COG0417	DNA replication proofreading
ASZ81_01229	COG2197	response regulator
ASZ81_01230	COG0322	excinuclease ABC activity
ASZ81_01236	COG3706	GGDEF domain
ASZ81_01236	COG0745	RESPONSE REGULATOR receiver
ASZ81_01239	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ASZ81_01240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASZ81_01240	COG0072	phenylalanine-tRNA ligase activity
ASZ81_01242	COG0776	regulation of translation
ASZ81_01245	COG0500	methyltransferase
ASZ81_01246	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ASZ81_01248	COG0295	cytidine deaminase activity
ASZ81_01249	COG1346	cytolysis
ASZ81_01251	COG2925	Exonuclease
ASZ81_01253	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ81_01255	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ASZ81_01256	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ASZ81_01259	COG2988	succinylglutamate desuccinylase activity
ASZ81_01260	COG4139	cobalamin transport
ASZ81_01261	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
ASZ81_01270	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASZ81_01271	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASZ81_01272	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASZ81_01276	COG2814	Major facilitator Superfamily
ASZ81_01278	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASZ81_01283	COG2989	Protein conserved in bacteria
ASZ81_01284	COG3108	Peptidase M15
ASZ81_01285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASZ81_01288	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASZ81_01293	COG1846	Transcriptional regulator
ASZ81_01294	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASZ81_01295	COG0726	polysaccharide deacetylase
ASZ81_01296	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASZ81_01298	COG1447	Phosphotransferase system cellobiose-specific component IIA
ASZ81_01299	COG1486	melibiose metabolic process
ASZ81_01300	COG3394	polysaccharide catabolic process
ASZ81_01301	COG1609	Transcriptional regulator
ASZ81_01302	COG2943	transferase activity, transferring hexosyl groups
ASZ81_01303	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ASZ81_01304	COG0840	transmembrane signaling receptor activity
ASZ81_01307	COG1448	Aminotransferase
ASZ81_01309	COG3437	response regulator, receiver
ASZ81_01309	COG2770	Histidine kinase
ASZ81_01310	COG0351	phosphomethylpyrimidine kinase
ASZ81_01311	COG0017	Asparaginyl-tRNA synthetase
ASZ81_01313	COG0720	synthase
ASZ81_01314	COG1760	l-serine dehydratase
ASZ81_01315	COG0814	amino acid
ASZ81_01316	COG0494	nUDIX hydrolase
ASZ81_01317	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASZ81_01320	COG3106	COG3106 Predicted ATPase
ASZ81_01321	COG3768	UPF0283 membrane protein
ASZ81_01322	COG3283	Transcriptional regulator of aromatic amino acids metabolism
ASZ81_01323	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ81_01326	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASZ81_01328	COG0471	metal ion transport
ASZ81_01329	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASZ81_01329	COG4191	Histidine kinase
ASZ81_01331	COG2990	Protein conserved in bacteria
ASZ81_01332	COG3713	MltA-interacting MipA family protein
ASZ81_01333	COG2205	protein histidine kinase activity
ASZ81_01334	COG0745	RESPONSE REGULATOR receiver
ASZ81_01340	COG1129	ABC transporter
ASZ81_01347	COG2186	Transcriptional regulator
ASZ81_01348	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ASZ81_01349	COG0372	Belongs to the citrate synthase family
ASZ81_01355	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASZ81_01357	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ASZ81_01359	COG0625	glutathione transferase activity
ASZ81_01360	COG3437	response regulator, receiver
ASZ81_01363	COG3706	GGDEF domain
ASZ81_01364	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ASZ81_01365	COG1254	Belongs to the acylphosphatase family
ASZ81_01366	COG2920	part of a sulfur-relay system
ASZ81_01367	COG0670	Belongs to the BI1 family
ASZ81_01368	COG1126	abc transporter atp-binding protein
ASZ81_01369	COG0765	amino acid transport
ASZ81_01370	COG4597	amino acid ABC transporter
ASZ81_01371	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASZ81_01373	COG0561	phosphatase activity
ASZ81_01374	COG0602	queuosine metabolic process
ASZ81_01375	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ASZ81_01381	COG3706	GGDEF domain
ASZ81_01382	COG0443	Heat shock 70 kDa protein
ASZ81_01383	COG0443	Heat shock 70 kDa protein
ASZ81_01391	COG1643	Atp-dependent helicase
ASZ81_01393	COG0443	Heat shock 70 kDa protein
ASZ81_01394	COG0095	Lipoate-protein ligase
ASZ81_01396	COG0583	DNA-binding transcription factor activity
ASZ81_01397	COG0477	Major facilitator Superfamily
ASZ81_01398	COG0415	Belongs to the DNA photolyase family
ASZ81_01399	COG2076	Multidrug Resistance protein
ASZ81_01403	COG2198	Histidine kinase
ASZ81_01403	COG0643	Histidine kinase
ASZ81_01405	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASZ81_01407	COG2201	protein-glutamate methylesterase activity
ASZ81_01408	COG0835	chemotaxis
ASZ81_01409	COG3290	protein histidine kinase activity
ASZ81_01409	COG0840	transmembrane signaling receptor activity
ASZ81_01411	COG0840	transmembrane signaling receptor activity
ASZ81_01413	COG0513	Belongs to the DEAD box helicase family
ASZ81_01415	COG1538	Outer membrane efflux protein
ASZ81_01416	COG1566	PFAM secretion protein HlyD family protein
ASZ81_01417	COG2814	Major facilitator Superfamily
ASZ81_01418	COG0840	transmembrane signaling receptor activity
ASZ81_01419	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ASZ81_01421	COG3501	Rhs element vgr protein
ASZ81_01426	COG1280	lysine exporter protein (LysE YggA)
ASZ81_01427	COG1115	amino acid carrier protein
ASZ81_01430	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASZ81_01431	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASZ81_01432	COG1177	transmembrane transport
ASZ81_01433	COG1176	ABC-type spermidine putrescine transport system, permease component I
ASZ81_01434	COG3842	ATPase activity
ASZ81_01438	COG0037	tRNA processing
ASZ81_01439	COG0589	response to stress
ASZ81_01440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASZ81_01443	COG2217	Heavy metal translocating P-type atpase
ASZ81_01445	COG2010	Cytochrome c
ASZ81_01448	COG3278	Belongs to the heme-copper respiratory oxidase family
ASZ81_01450	COG0784	Response regulator, receiver
ASZ81_01450	COG2205	protein histidine kinase activity
ASZ81_01455	COG2994	toxin metabolic process
ASZ81_01456	COG1073	alpha beta
ASZ81_01456	COG3064	Membrane
ASZ81_01456	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ASZ81_01458	COG4128	Pfam Zonular occludens toxin
ASZ81_01481	COG3120	sequence-specific DNA binding
ASZ81_01482	COG1067	ATP-dependent peptidase activity
ASZ81_01483	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASZ81_01487	COG0116	Belongs to the methyltransferase superfamily
ASZ81_01487	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ASZ81_01490	COG0167	dihydroorotate dehydrogenase activity
ASZ81_01493	COG0308	aminopeptidase N
ASZ81_01496	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
ASZ81_01497	COG1956	GAF domain-containing protein
ASZ81_01498	COG1132	(ABC) transporter
ASZ81_01499	COG2995	paraquat-inducible protein a
ASZ81_01500	COG3008	intermembrane lipid transfer
ASZ81_01501	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ASZ81_01501	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ASZ81_01502	COG2996	Protein conserved in bacteria
ASZ81_01505	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASZ81_01507	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ASZ81_01510	COG0437	4 iron, 4 sulfur cluster binding
ASZ81_01511	COG3383	formate dehydrogenase (NAD+) activity
ASZ81_01511	COG0243	molybdopterin cofactor binding
ASZ81_01517	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ASZ81_01518	COG0488	(ABC) transporter
ASZ81_01519	COG3852	Histidine kinase
ASZ81_01520	COG2204	response regulator
ASZ81_01522	COG4662	Binding-protein-dependent transport system inner membrane component
ASZ81_01523	COG3842	ATPase activity
ASZ81_01524	COG0746	molybdenum cofactor guanylyltransferase activity
ASZ81_01530	COG1940	carbohydrate kinase activity
ASZ81_01533	COG0840	transmembrane signaling receptor activity
ASZ81_01534	COG0791	NLP P60 protein
ASZ81_01538	COG0534	Mate efflux family protein
ASZ81_01540	COG1793	dna ligase
ASZ81_01542	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ASZ81_01543	COG0848	biopolymer transport protein
ASZ81_01544	COG0811	peptide transport
ASZ81_01545	COG0811	peptide transport
ASZ81_01548	COG1175	transmembrane transport
ASZ81_01549	COG0395	ABC-type sugar transport system, permease component
ASZ81_01550	COG3842	ATPase activity
ASZ81_01551	COG1349	DNA-binding transcription factor activity
ASZ81_01552	COG0584	glycerophosphoryl diester phosphodiesterase
ASZ81_01553	COG2731	YhcH YjgK YiaL family protein
ASZ81_01554	COG0251	oxidation-reduction process
ASZ81_01556	COG1609	Transcriptional regulator
ASZ81_01557	COG2723	6-phospho-beta-galactosidase activity
ASZ81_01558	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ASZ81_01559	COG0583	DNA-binding transcription factor activity
ASZ81_01563	COG1136	(ABC) transporter
ASZ81_01563	COG0577	efflux transmembrane transporter activity
ASZ81_01564	COG1136	(ABC) transporter
ASZ81_01564	COG0577	efflux transmembrane transporter activity
ASZ81_01565	COG1136	(ABC) transporter
ASZ81_01565	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASZ81_01566	COG1294	oxidase, subunit
ASZ81_01567	COG1271	oxidase subunit
ASZ81_01575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASZ81_01577	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASZ81_01581	COG0753	catalase activity
ASZ81_01584	COG3527	Alpha-acetolactate decarboxylase
ASZ81_01587	COG2199	diguanylate cyclase activity
ASZ81_01587	COG2200	EAL domain
ASZ81_01588	COG3706	GGDEF domain
ASZ81_01589	COG2017	converts alpha-aldose to the beta-anomer
ASZ81_01590	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ASZ81_01591	COG1085	galactose-1-phosphate uridylyltransferase
ASZ81_01596	COG3706	GGDEF domain
ASZ81_01596	COG0745	RESPONSE REGULATOR receiver
ASZ81_01599	COG0835	chemotaxis
ASZ81_01599	COG0784	Response regulator, receiver
ASZ81_01601	COG4565	transcriptional regulatory protein
ASZ81_01602	COG3290	protein histidine kinase activity
ASZ81_01604	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ81_01608	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ASZ81_01609	COG3063	Type IV pilus biogenesis stability protein PilW
ASZ81_01612	COG1451	nucleotide metabolic process
ASZ81_01614	COG0583	DNA-binding transcription factor activity
ASZ81_01618	COG1538	Outer membrane efflux protein
ASZ81_01620	COG0019	diaminopimelate decarboxylase activity
ASZ81_01621	COG1748	Saccharopine dehydrogenase
ASZ81_01623	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASZ81_01626	COG4181	ATPase activity
ASZ81_01627	COG0534	Mate efflux family protein
ASZ81_01628	COG0702	epimerase
ASZ81_01630	COG2814	Major facilitator Superfamily
ASZ81_01631	COG1187	pseudouridine synthase activity
ASZ81_01632	COG1061	Type III restriction enzyme res subunit
ASZ81_01636	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ASZ81_01637	COG2203	Gaf domain
ASZ81_01637	COG5001	Diguanylate cyclase
ASZ81_01637	COG3706	GGDEF domain
ASZ81_01637	COG4251	negative regulation of phosphorylation
ASZ81_01639	COG0840	transmembrane signaling receptor activity
ASZ81_01645	COG4934	collagen metabolic process
ASZ81_01649	COG2239	Acts as a magnesium transporter
ASZ81_01652	COG0814	amino acid
ASZ81_01653	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ81_01654	COG1131	(ABC) transporter
ASZ81_01655	COG0842	Transport permease protein
ASZ81_01657	COG3313	Fe-S protein
ASZ81_01659	COG4134	Bacterial extracellular solute-binding protein
ASZ81_01660	COG4135	transport system, permease component
ASZ81_01661	COG4136	ATPase activity
ASZ81_01662	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASZ81_01663	COG0564	pseudouridine synthase activity
ASZ81_01665	COG0733	neurotransmitter:sodium symporter activity
ASZ81_01667	COG0626	cystathionine gamma-synthase activity
ASZ81_01668	COG2818	Glycosylase
ASZ81_01671	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ81_01674	COG1842	Phage shock protein A
ASZ81_01675	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ASZ81_01677	COG4168	peptide transport system, permease
ASZ81_01678	COG4171	peptide transport system, permease
ASZ81_01680	COG4172	Belongs to the ABC transporter superfamily
ASZ81_01683	COG1227	inorganic diphosphatase activity
ASZ81_01688	COG0243	molybdopterin cofactor binding
ASZ81_01689	COG3005	denitrification pathway
ASZ81_01690	COG4459	periplasmic nitrate reductase
ASZ81_01692	COG2116	formate transmembrane transporter activity
ASZ81_01694	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASZ81_01695	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ASZ81_01697	COG2917	probably involved in intracellular septation
ASZ81_01698	COG1607	acyl-coa hydrolase
ASZ81_01699	COG2350	Protein conserved in bacteria
ASZ81_01701	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ASZ81_01702	COG0583	DNA-binding transcription factor activity
ASZ81_01705	COG0612	Peptidase, M16
ASZ81_01707	COG1032	radical SAM domain protein
ASZ81_01710	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ASZ81_01711	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ASZ81_01712	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
ASZ81_01713	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASZ81_01714	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ASZ81_01715	COG0745	RESPONSE REGULATOR receiver
ASZ81_01716	COG3381	protein complex oligomerization
ASZ81_01717	COG1609	Transcriptional regulator
ASZ81_01718	COG3070	regulator of competence-specific genes
ASZ81_01722	COG0297	glycogen (starch) synthase activity
ASZ81_01723	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ASZ81_01725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASZ81_01727	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ASZ81_01729	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ASZ81_01730	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ASZ81_01731	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASZ81_01733	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASZ81_01739	COG1012	belongs to the aldehyde dehydrogenase family
ASZ81_01740	COG1309	transcriptional regulator
ASZ81_01744	COG0668	transmembrane transport
ASZ81_01745	COG2995	paraquat-inducible protein a
ASZ81_01746	COG3008	intermembrane lipid transfer
ASZ81_01746	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ASZ81_01748	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ81_01751	COG0582	viral genome integration into host DNA
ASZ81_01752	COG0582	viral genome integration into host DNA
ASZ81_01753	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASZ81_01757	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ASZ81_01761	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ASZ81_01765	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ASZ81_01766	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ASZ81_01767	COG1737	Transcriptional regulator
ASZ81_01768	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASZ81_01769	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASZ81_01770	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASZ81_01771	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASZ81_01772	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ASZ81_01773	COG1940	carbohydrate kinase activity
ASZ81_01774	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ASZ81_01775	COG4409	exo-alpha-(2->6)-sialidase activity
ASZ81_01777	COG2003	Belongs to the UPF0758 family
ASZ81_01782	COG3941	tape measure
ASZ81_01789	COG0488	(ABC) transporter
ASZ81_01804	COG0415	Belongs to the DNA photolyase family
ASZ81_01806	COG4628	conserved protein (DUF2132)
ASZ81_01807	COG3284	Transcriptional regulator
ASZ81_01808	COG1012	belongs to the aldehyde dehydrogenase family
ASZ81_01810	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ81_01811	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ81_01812	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ81_01814	COG2207	Transcriptional regulator
ASZ81_01815	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ81_01815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ81_01815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ81_01816	COG1482	cell wall glycoprotein biosynthetic process
ASZ81_01818	COG0784	Response regulator, receiver
ASZ81_01818	COG5002	protein histidine kinase activity
ASZ81_01820	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ASZ81_01822	COG2885	chlorophyll binding
ASZ81_01823	COG0823	Involved in the tonB-independent uptake of proteins
ASZ81_01826	COG0811	peptide transport
ASZ81_01827	COG0824	Thioesterase
ASZ81_01828	COG1294	oxidase, subunit
ASZ81_01829	COG1271	oxidase subunit
ASZ81_01830	COG2255	four-way junction helicase activity
ASZ81_01831	COG0632	four-way junction helicase activity
ASZ81_01832	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ASZ81_01833	COG0215	cysteine-tRNA ligase activity
ASZ81_01834	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ASZ81_01835	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASZ81_01836	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ASZ81_01838	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ASZ81_01839	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASZ81_01840	COG1199	ATP-dependent helicase activity
ASZ81_01841	COG0730	response to heat
ASZ81_01842	COG3923	Primosomal replication protein n
ASZ81_01844	COG0840	transmembrane signaling receptor activity
ASZ81_01845	COG0708	Exodeoxyribonuclease III
ASZ81_01846	COG4160	amino acid transport
ASZ81_01847	COG4215	(ABC) transporter
ASZ81_01851	COG1882	Formate acetyltransferase
ASZ81_01853	COG0840	transmembrane signaling receptor activity
ASZ81_01854	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ASZ81_01856	COG3013	Belongs to the UPF0304 family
ASZ81_01857	COG2766	serine protein kinase
ASZ81_01858	COG2718	Belongs to the UPF0229 family
ASZ81_01859	COG2719	SpoVR family
ASZ81_01860	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ASZ81_01862	COG1663	tetraacyldisaccharide 4'-kinase activity
ASZ81_01863	COG1132	(ABC) transporter
ASZ81_01864	COG2333	competence protein COMEC
ASZ81_01864	COG0658	competence protein
ASZ81_01866	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASZ81_01867	COG1136	(ABC) transporter
ASZ81_01868	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASZ81_01870	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ASZ81_01874	COG1252	NADH dehydrogenase
ASZ81_01881	COG0537	adenosine 5'-monophosphoramidase activity
ASZ81_01884	COG2186	Transcriptional regulator
ASZ81_01885	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASZ81_01886	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ASZ81_01887	COG1674	ftsk spoiiie
ASZ81_01890	COG0686	Belongs to the AlaDH PNT family
ASZ81_01892	COG0583	DNA-binding transcription factor activity
ASZ81_01896	COG0284	orotidine-5'-phosphate decarboxylase activity
ASZ81_01897	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ASZ81_01898	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ASZ81_01899	COG0776	regulation of translation
ASZ81_01900	COG0539	negative regulation of cytoplasmic translation
ASZ81_01901	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ASZ81_01902	COG1555	photosystem II stabilization
ASZ81_01903	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASZ81_01904	COG0776	regulation of translation
ASZ81_01905	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ASZ81_01906	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASZ81_01908	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASZ81_01910	COG4191	Histidine kinase
ASZ81_01912	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASZ81_01913	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASZ81_01914	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASZ81_01915	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ASZ81_01918	COG5001	Diguanylate cyclase
ASZ81_01918	COG3300	MHYT domain
ASZ81_01920	COG4589	Belongs to the CDS family
ASZ81_01927	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASZ81_01929	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASZ81_01933	COG0243	molybdopterin cofactor binding
ASZ81_01934	COG3005	denitrification pathway
ASZ81_01935	COG3469	chitinase activity
ASZ81_01935	COG3325	Belongs to the glycosyl hydrolase 18 family
ASZ81_01936	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASZ81_01938	COG2951	lytic endotransglycosylase activity
ASZ81_01939	COG3100	YcgL domain-containing protein
ASZ81_01940	COG0850	regulation of cytokinetic process
ASZ81_01941	COG2894	cell division
ASZ81_01942	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ASZ81_01943	COG3015	lipoprotein NlpE involved in copper resistance
ASZ81_01947	COG0477	Major facilitator Superfamily
ASZ81_01949	COG0840	transmembrane signaling receptor activity
ASZ81_01950	COG1396	sequence-specific DNA binding
ASZ81_01951	COG3135	benzoate transporter
ASZ81_01953	COG1441	menaquinone biosynthetic process
ASZ81_01955	COG0596	Alpha beta hydrolase
ASZ81_01956	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ASZ81_01957	COG1169	isochorismate synthase
ASZ81_01958	COG0436	Aminotransferase
ASZ81_01959	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ASZ81_01960	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ASZ81_01964	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ASZ81_01965	COG0318	PFAM AMP-dependent synthetase and ligase
ASZ81_01966	COG0596	Alpha beta hydrolase
ASZ81_01969	COG1214	PFAM Peptidase M22, glycoprotease
ASZ81_01970	COG1199	ATP-dependent helicase activity
ASZ81_01972	COG0788	formyltetrahydrofolate deformylase activity
ASZ81_01973	COG1902	pentaerythritol trinitrate reductase activity
ASZ81_01973	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASZ81_01974	COG0616	signal peptide processing
ASZ81_01975	COG0252	asparaginase activity
ASZ81_01976	COG3139	Protein of unknown function (DUF1315)
ASZ81_01979	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ81_01980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASZ81_01981	COG0676	glucose-6-phosphate 1-epimerase activity
ASZ81_01983	COG2226	methyltransferase
ASZ81_01986	COG0784	Response regulator, receiver
ASZ81_01986	COG0835	chemotaxis
ASZ81_01987	COG1940	carbohydrate kinase activity
ASZ81_01989	COG4667	esterase of the alpha-beta hydrolase superfamily
ASZ81_01992	COG0733	neurotransmitter:sodium symporter activity
ASZ81_01993	COG1263	PTS System
ASZ81_01993	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ81_01994	COG0084	hydrolase, TatD family'
ASZ81_01996	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASZ81_01997	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ASZ81_01998	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASZ81_01999	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASZ81_02000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASZ81_02001	COG1028	Short-chain dehydrogenase reductase Sdr
ASZ81_02002	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ASZ81_02003	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASZ81_02004	COG0416	fatty acid biosynthetic process
ASZ81_02005	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ASZ81_02006	COG1399	metal-binding, possibly nucleic acid-binding protein
ASZ81_02007	COG0424	maF-like protein
ASZ81_02008	COG0564	pseudouridine synthase activity
ASZ81_02009	COG1530	ribonuclease E activity
ASZ81_02010	COG0659	secondary active sulfate transmembrane transporter activity
ASZ81_02012	COG1454	alcohol dehydrogenase
ASZ81_02012	COG1012	belongs to the aldehyde dehydrogenase family
ASZ81_02013	COG2095	MarC family integral membrane protein
ASZ81_02014	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASZ81_02015	COG1757	Na H antiporter
ASZ81_02017	COG3081	Nucleoid-associated protein
ASZ81_02019	COG3083	sulfuric ester hydrolase activity
ASZ81_02022	COG0123	including yeast histone deacetylase and acetoin utilization protein
ASZ81_02023	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASZ81_02024	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ASZ81_02029	COG2853	Lipoprotein
ASZ81_02031	COG3088	subunit of a heme lyase
ASZ81_02031	COG4235	cytochrome complex assembly
ASZ81_02032	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASZ81_02033	COG1138	Cytochrome C-type biogenesis protein
ASZ81_02034	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ASZ81_02036	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASZ81_02037	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASZ81_02038	COG4133	protoheme IX ABC transporter activity
ASZ81_02040	COG0835	chemotaxis
ASZ81_02042	COG1192	Involved in chromosome partitioning
ASZ81_02043	COG2201	protein-glutamate methylesterase activity
ASZ81_02044	COG0643	Histidine kinase
ASZ81_02044	COG2198	Histidine kinase
ASZ81_02045	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ASZ81_02048	COG0455	bacterial-type flagellum organization
ASZ81_02051	COG2062	phosphohistidine phosphatase, SixA
ASZ81_02053	COG1025	Belongs to the peptidase M16 family
ASZ81_02055	COG0018	arginyl-trna synthetase
ASZ81_02059	COG1918	ferrous iron import across plasma membrane
ASZ81_02060	COG4977	sequence-specific DNA binding
ASZ81_02061	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ASZ81_02062	COG1121	(ABC) transporter
ASZ81_02063	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASZ81_02065	COG0045	succinate-CoA ligase (ADP-forming) activity
ASZ81_02066	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASZ81_02067	COG0567	Dehydrogenase, E1 component
ASZ81_02069	COG1053	succinate dehydrogenase
ASZ81_02070	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ASZ81_02071	COG2009	succinate dehydrogenase
ASZ81_02072	COG0372	Belongs to the citrate synthase family
ASZ81_02073	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ASZ81_02075	COG0033	Phosphoglucomutase
ASZ81_02076	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ASZ81_02077	COG0596	Alpha beta hydrolase
ASZ81_02080	COG1346	cytolysis
ASZ81_02082	COG0583	DNA-binding transcription factor activity
ASZ81_02084	COG0735	belongs to the Fur family
ASZ81_02085	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASZ81_02086	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASZ81_02087	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASZ81_02088	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASZ81_02088	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ASZ81_02089	COG0431	NADPH-dependent FMN reductase
ASZ81_02091	COG3101	peptidyl-lysine hydroxylation
ASZ81_02092	COG2860	membrane
ASZ81_02093	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ASZ81_02094	COG2890	protein-(glutamine-N5) methyltransferase activity
ASZ81_02096	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ASZ81_02097	COG1684	flagellar biosynthetic protein fliR
ASZ81_02098	COG1987	bacterial-type flagellum assembly
ASZ81_02103	COG1580	Controls the rotational direction of flagella during chemotaxis
ASZ81_02108	COG1317	bacterial-type flagellum organization
ASZ81_02109	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASZ81_02111	COG1677	Flagellar hook-basal body complex protein FliE
ASZ81_02112	COG2204	response regulator
ASZ81_02113	COG4191	Histidine kinase
ASZ81_02114	COG2204	response regulator
ASZ81_02115	COG1516	flagellar protein fliS
ASZ81_02117	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ASZ81_02118	COG1334	flagellar protein FlaG
ASZ81_02119	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ81_02120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ81_02121	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ81_02122	COG2837	iron assimilation
ASZ81_02126	COG1393	Belongs to the ArsC family
ASZ81_02127	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASZ81_02128	COG1876	peptidase activity
ASZ81_02130	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ASZ81_02131	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASZ81_02133	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ASZ81_02134	COG0840	transmembrane signaling receptor activity
ASZ81_02137	COG4783	chaperone-mediated protein folding
ASZ81_02138	COG1393	Belongs to the ArsC family
ASZ81_02142	COG2233	PERMEase
ASZ81_02143	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ASZ81_02145	COG0737	Belongs to the 5'-nucleotidase family
ASZ81_02146	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ASZ81_02147	COG2912	Transglutaminase-like superfamily
ASZ81_02148	COG3094	Invasion gene expression up-regulator, SirB
ASZ81_02149	COG2890	protein-(glutamine-N5) methyltransferase activity
ASZ81_02150	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ASZ81_02151	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ASZ81_02152	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ASZ81_02153	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ASZ81_02154	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASZ81_02155	COG0193	aminoacyl-tRNA hydrolase activity
ASZ81_02156	COG0012	GTP binding
ASZ81_02174	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ81_02202	COG4695	Portal protein
ASZ81_02219	COG4974	Belongs to the 'phage' integrase family
ASZ81_02221	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ81_02225	COG1705	Flagellar rod assembly protein muramidase FlgJ
ASZ81_02225	COG3951	Flagellar rod assembly protein muramidase FlgJ
ASZ81_02226	COG1706	bacterial-type flagellum-dependent cell motility
ASZ81_02227	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ASZ81_02228	COG4786	Flagellar basal body rod
ASZ81_02229	COG4787	bacterial-type flagellum-dependent cell motility
ASZ81_02230	COG1749	Flagellar hook protein flgE
ASZ81_02231	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ASZ81_02232	COG1558	bacterial-type flagellum-dependent cell motility
ASZ81_02233	COG1815	bacterial-type flagellum-dependent cell motility
ASZ81_02234	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASZ81_02235	COG0784	Response regulator, receiver
ASZ81_02235	COG0835	chemotaxis
ASZ81_02242	COG3433	isochorismatase activity
ASZ81_02242	COG2226	methyltransferase
ASZ81_02242	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASZ81_02243	COG2375	cellular response to nickel ion
ASZ81_02244	COG4774	siderophore transport
ASZ81_02244	COG1629	transport
ASZ81_02247	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASZ81_02248	COG2217	Heavy metal translocating P-type atpase
ASZ81_02248	COG2608	mercury ion transmembrane transporter activity
ASZ81_02253	COG3735	TraB family
ASZ81_02256	COG2840	Smr protein MutS2
ASZ81_02257	COG1187	pseudouridine synthase activity
ASZ81_02258	COG3706	GGDEF domain
ASZ81_02259	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ASZ81_02260	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ASZ81_02261	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ASZ81_02262	COG0121	glutamine amidotransferase
ASZ81_02263	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ASZ81_02264	COG1960	acyl-CoA dehydrogenase activity
ASZ81_02266	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASZ81_02267	COG0328	RNA-DNA hybrid ribonuclease activity
ASZ81_02268	COG2226	methyltransferase
ASZ81_02269	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASZ81_02270	COG1388	LysM domain
ASZ81_02270	COG0741	lytic transglycosylase activity
ASZ81_02272	COG0347	Belongs to the P(II) protein family
ASZ81_02273	COG3479	Phenolic acid decarboxylase
ASZ81_02275	COG0037	tRNA processing
ASZ81_02276	COG0825	malonyl-CoA metabolic process
ASZ81_02277	COG0587	DNA-directed DNA polymerase activity
ASZ81_02278	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ASZ81_02279	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASZ81_02280	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASZ81_02281	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASZ81_02282	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASZ81_02283	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ASZ81_02285	COG0750	zinc metalloprotease
ASZ81_02286	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ASZ81_02287	COG0575	Belongs to the CDS family
ASZ81_02288	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASZ81_02289	COG0233	cytoplasmic translational termination
ASZ81_02290	COG0528	UMP kinase activity
ASZ81_02291	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ASZ81_02292	COG0052	Belongs to the universal ribosomal protein uS2 family
ASZ81_02293	COG0024	Methionine aminopeptidase
ASZ81_02294	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ASZ81_02296	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ASZ81_02297	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ASZ81_02298	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASZ81_02299	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ASZ81_02302	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASZ81_02302	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASZ81_02303	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASZ81_02304	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ASZ81_02305	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ASZ81_02308	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ASZ81_02309	COG2252	PERMEase
ASZ81_02310	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASZ81_02311	COG0189	ligase activity
ASZ81_02311	COG4067	protein conserved in archaea
ASZ81_02312	COG0189	ligase activity
ASZ81_02314	COG0733	neurotransmitter:sodium symporter activity
ASZ81_02315	COG3706	GGDEF domain
ASZ81_02317	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASZ81_02319	COG1477	protein flavinylation
ASZ81_02320	COG2871	sodium ion transport
ASZ81_02321	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASZ81_02322	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASZ81_02323	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASZ81_02324	COG1805	sodium ion transport
ASZ81_02325	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASZ81_02326	COG0271	Belongs to the BolA IbaG family
ASZ81_02328	COG2813	Specifically methylates the guanine in position
ASZ81_02330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ASZ81_02331	COG2211	Major facilitator Superfamily
ASZ81_02333	COG1595	DNA-templated transcription, initiation
ASZ81_02335	COG3248	Nucleoside-binding outer membrane protein
ASZ81_02336	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ASZ81_02337	COG0693	protein deglycase activity
ASZ81_02338	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASZ81_02339	COG2166	iron-sulfur cluster assembly
ASZ81_02340	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ASZ81_02341	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ASZ81_02343	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASZ81_02343	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ASZ81_02345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ASZ81_02346	COG1074	ATP-dependent DNA helicase activity
ASZ81_02347	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ASZ81_02350	COG3141	response to X-ray
ASZ81_02351	COG2171	N-acyltransferase activity
ASZ81_02353	COG0456	acetyltransferase
ASZ81_02354	COG0569	domain protein
ASZ81_02354	COG0189	ligase activity
ASZ81_02357	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASZ81_02358	COG1609	Transcriptional regulator
ASZ81_02359	COG3250	beta-galactosidase activity
ASZ81_02362	COG1022	Amp-dependent synthetase and ligase
ASZ81_02363	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASZ81_02364	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ASZ81_02366	COG0560	Phosphoserine phosphatase
ASZ81_02368	COG0813	purine-nucleoside phosphorylase activity
ASZ81_02369	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ASZ81_02370	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ASZ81_02371	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ASZ81_02373	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASZ81_02374	COG0084	hydrolase, TatD family'
ASZ81_02377	COG1115	amino acid carrier protein
ASZ81_02380	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ASZ81_02381	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ASZ81_02382	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
ASZ81_02383	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ASZ81_02384	COG0083	homoserine kinase activity
ASZ81_02387	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ASZ81_02389	COG0745	RESPONSE REGULATOR receiver
ASZ81_02390	COG5002	protein histidine kinase activity
ASZ81_02390	COG2198	Histidine kinase
ASZ81_02390	COG0784	Response regulator, receiver
ASZ81_02391	COG2203	Gaf domain
ASZ81_02391	COG3706	GGDEF domain
ASZ81_02391	COG5001	Diguanylate cyclase
ASZ81_02391	COG4251	negative regulation of phosphorylation
ASZ81_02392	COG1242	4 iron, 4 sulfur cluster binding
ASZ81_02394	COG0070	glutamate synthase
ASZ81_02394	COG0067	glutamate synthase
ASZ81_02394	COG0069	glutamate synthase activity
ASZ81_02396	COG0070	glutamate synthase
ASZ81_02396	COG0069	glutamate synthase activity
ASZ81_02396	COG0067	glutamate synthase
ASZ81_02397	COG0493	'glutamate synthase
ASZ81_02399	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ASZ81_02401	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASZ81_02402	COG2860	membrane
ASZ81_02403	COG0730	response to heat
ASZ81_02405	COG4172	Belongs to the ABC transporter superfamily
ASZ81_02408	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ASZ81_02409	COG0505	Belongs to the CarA family
ASZ81_02411	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ASZ81_02412	COG0494	nUDIX hydrolase
ASZ81_02413	COG0653	protein targeting
ASZ81_02415	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ASZ81_02416	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ASZ81_02417	COG0849	cell division
ASZ81_02418	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ASZ81_02419	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASZ81_02420	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ASZ81_02421	COG0772	Belongs to the SEDS family
ASZ81_02422	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ASZ81_02423	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASZ81_02424	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASZ81_02425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ASZ81_02426	COG0768	penicillin binding
ASZ81_02427	COG3116	cell division
ASZ81_02428	COG0275	rRNA processing
ASZ81_02429	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASZ81_02430	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASZ81_02431	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ASZ81_02432	COG2186	Transcriptional regulator
ASZ81_02433	COG0737	Belongs to the 5'-nucleotidase family
ASZ81_02434	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASZ81_02435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASZ81_02436	COG4974	Belongs to the 'phage' integrase family
ASZ81_02437	COG0716	FMN binding
ASZ81_02441	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASZ81_02442	COG1459	type II secretion system
ASZ81_02444	COG0237	dephospho-CoA kinase activity
ASZ81_02445	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ASZ81_02446	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ASZ81_02447	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ASZ81_02448	COG0187	DNA topoisomerase II activity
ASZ81_02449	COG3150	esterase
ASZ81_02451	COG3151	Protein conserved in bacteria
ASZ81_02452	COG0494	nUDIX hydrolase
ASZ81_02453	COG1538	Outer membrane efflux protein
ASZ81_02455	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ASZ81_02456	COG0840	transmembrane signaling receptor activity
ASZ81_02457	COG3025	triphosphatase activity
ASZ81_02458	COG1392	Phosphate transport regulator
ASZ81_02459	COG0306	phosphate transporter
ASZ81_02460	COG4991	sh3 domain protein
ASZ81_02462	COG3409	Peptidoglycan-binding domain 1 protein
ASZ81_02462	COG3267	Type II secretory pathway component ExeA
ASZ81_02463	COG0617	tRNA 3'-terminal CCA addition
ASZ81_02464	COG0148	phosphopyruvate hydratase activity
ASZ81_02465	COG0504	CTP synthase activity
ASZ81_02467	COG3956	TIGRFAM MazG family protein
ASZ81_02468	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASZ81_02469	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASZ81_02471	COG5001	Diguanylate cyclase
ASZ81_02474	COG0736	holo-[acyl-carrier-protein] synthase activity
ASZ81_02475	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ASZ81_02476	COG1381	Involved in DNA repair and RecF pathway recombination
ASZ81_02477	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ASZ81_02478	COG0571	ribonuclease III activity
ASZ81_02479	COG0681	Belongs to the peptidase S26 family
ASZ81_02480	COG0481	GTPase activity
ASZ81_02481	COG3086	response to oxidative stress
ASZ81_02482	COG3026	antisigma factor binding
ASZ81_02484	COG1595	DNA-templated transcription, initiation
ASZ81_02485	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ASZ81_02487	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ASZ81_02488	COG0354	folic acid binding
ASZ81_02490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASZ81_02491	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASZ81_02493	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ASZ81_02494	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ASZ81_02495	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ASZ81_02496	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASZ81_02497	COG0440	acetolactate synthase activity
ASZ81_02498	COG0028	Belongs to the TPP enzyme family
ASZ81_02499	COG1022	Amp-dependent synthetase and ligase
ASZ81_02500	COG0583	DNA-binding transcription factor activity
ASZ81_02504	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASZ81_02505	COG0473	3-isopropylmalate dehydrogenase activity
ASZ81_02506	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ASZ81_02507	COG0066	3-isopropylmalate dehydratase activity
ASZ81_02517	COG3437	response regulator, receiver
ASZ81_02520	COG0795	lipopolysaccharide-transporting ATPase activity
ASZ81_02521	COG0795	lipopolysaccharide-transporting ATPase activity
ASZ81_02522	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASZ81_02523	COG2927	DNA polymerase III (CHI subunit)
ASZ81_02524	COG0525	valine-tRNA ligase activity
ASZ81_02525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASZ81_02526	COG0564	pseudouridine synthase activity
ASZ81_02527	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASZ81_02529	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ASZ81_02530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ASZ81_02531	COG0540	Belongs to the ATCase OTCase family
ASZ81_02532	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
ASZ81_02533	COG0251	oxidation-reduction process
ASZ81_02534	COG0204	Acyl-transferase
ASZ81_02535	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ASZ81_02536	COG5007	Belongs to the BolA IbaG family
ASZ81_02538	COG2854	intermembrane phospholipid transfer
ASZ81_02539	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ASZ81_02540	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASZ81_02541	COG1127	ABC transporter
ASZ81_02543	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ASZ81_02543	COG0517	IMP dehydrogenase activity
ASZ81_02546	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ASZ81_02547	COG1137	ATPase activity
ASZ81_02549	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ASZ81_02550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ81_02551	COG1660	Displays ATPase and GTPase activities
ASZ81_02552	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ81_02553	COG2239	Acts as a magnesium transporter
ASZ81_02554	COG0312	modulator of DNA gyrase
ASZ81_02555	COG3028	Belongs to the UPF0307 family
ASZ81_02556	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ASZ81_02557	COG1178	ABC-type Fe3 transport system permease component
ASZ81_02558	COG4143	(ABC) transporter
ASZ81_02559	COG0163	prenyltransferase activity
ASZ81_02560	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASZ81_02561	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ASZ81_02562	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ASZ81_02563	COG2105	PFAM AIG2 family protein
ASZ81_02565	COG0729	surface antigen
ASZ81_02566	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ81_02567	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ASZ81_02570	COG1136	(ABC) transporter
ASZ81_02574	COG0529	Catalyzes the synthesis of activated sulfate
ASZ81_02575	COG2895	sulfate adenylyltransferase (ATP) activity
ASZ81_02576	COG0175	sulfate reduction
ASZ81_02577	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ASZ81_02577	COG1648	precorrin-2 dehydrogenase activity
ASZ81_02578	COG0737	Belongs to the 5'-nucleotidase family
ASZ81_02580	COG0513	Belongs to the DEAD box helicase family
ASZ81_02581	COG2153	protein acetylation
ASZ81_02582	COG0697	spore germination
ASZ81_02584	COG0545	Peptidyl-prolyl cis-trans isomerase
ASZ81_02586	COG0203	ribosomal protein L17
ASZ81_02587	COG0202	RNA polymerase activity
ASZ81_02588	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ASZ81_02589	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ASZ81_02590	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ASZ81_02592	COG0201	protein transport
ASZ81_02593	COG0200	Binds to the 23S rRNA
ASZ81_02594	COG1841	ribosomal large subunit assembly
ASZ81_02595	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ASZ81_02596	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ASZ81_02597	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ASZ81_02598	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ASZ81_02599	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASZ81_02600	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ASZ81_02601	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ASZ81_02602	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ASZ81_02603	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ASZ81_02604	COG0255	Belongs to the universal ribosomal protein uL29 family
ASZ81_02605	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ASZ81_02606	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASZ81_02607	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ASZ81_02608	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ASZ81_02609	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ASZ81_02610	COG0089	rRNA binding
ASZ81_02611	COG0088	Forms part of the polypeptide exit tunnel
ASZ81_02612	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASZ81_02613	COG0051	transcription antitermination factor activity, RNA binding
ASZ81_02614	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASZ81_02615	COG0557	exoribonuclease II activity
ASZ81_02616	COG3083	sulfuric ester hydrolase activity
ASZ81_02617	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ASZ81_02619	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ASZ81_02621	COG1047	Peptidyl-prolyl cis-trans
ASZ81_02624	COG2249	NAD(P)H dehydrogenase (quinone) activity
ASZ81_02625	COG0488	(ABC) transporter
ASZ81_02627	COG0429	hydrolase of the alpha beta-hydrolase fold
ASZ81_02629	COG3954	Phosphoribulokinase
ASZ81_02630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASZ81_02632	COG1012	belongs to the aldehyde dehydrogenase family
ASZ81_02634	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASZ81_02636	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASZ81_02639	COG0180	Tryptophanyl-tRNA synthetase
ASZ81_02640	COG0546	phosphoglycolate phosphatase activity
ASZ81_02641	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASZ81_02642	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ASZ81_02644	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ASZ81_02645	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ASZ81_02651	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ASZ81_02653	COG0678	peroxiredoxin activity
ASZ81_02653	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASZ81_02654	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASZ81_02656	COG0165	Argininosuccinate lyase
ASZ81_02657	COG0137	argininosuccinate synthase activity
ASZ81_02658	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASZ81_02659	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASZ81_02660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASZ81_02661	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ASZ81_02664	COG1045	serine acetyltransferase
ASZ81_02665	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ASZ81_02666	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ASZ81_02667	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASZ81_02668	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ASZ81_02669	COG1053	succinate dehydrogenase
ASZ81_02670	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ASZ81_02671	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ASZ81_02672	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ASZ81_02673	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASZ81_02674	COG1509	lysine 2,3-aminomutase activity
ASZ81_02676	COG0459	protein refolding
ASZ81_02677	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ASZ81_02682	COG0149	triose-phosphate isomerase activity
ASZ81_02684	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ASZ81_02685	COG1575	Belongs to the MenA family. Type 1 subfamily
ASZ81_02686	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ASZ81_02687	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ASZ81_02688	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ASZ81_02690	COG1609	Transcriptional regulator
ASZ81_02691	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ASZ81_02692	COG0254	rRNA binding
ASZ81_02694	COG0281	malic enzyme
ASZ81_02695	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
ASZ81_02696	COG0626	cystathionine gamma-synthase activity
ASZ81_02697	COG0460	homoserine dehydrogenase
ASZ81_02697	COG0527	aspartate kinase activity
ASZ81_02698	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ASZ81_02699	COG3074	FtsZ-dependent cytokinesis
ASZ81_02700	COG1494	fructose-1,6-bisphosphatase
ASZ81_02701	COG0205	6-phosphofructokinase activity
ASZ81_02702	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ASZ81_02704	COG0745	RESPONSE REGULATOR receiver
ASZ81_02705	COG2205	protein histidine kinase activity
ASZ81_02707	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ASZ81_02708	COG3030	protein affecting phage T7 exclusion by the F plasmid
ASZ81_02709	COG3706	GGDEF domain
ASZ81_02710	COG1027	Aspartate ammonia-lyase
ASZ81_02711	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ASZ81_02715	COG4232	protein-disulfide reductase activity
ASZ81_02717	COG3263	regulation of cellular component size
ASZ81_02719	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASZ81_02720	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ASZ81_02721	COG0194	GDP metabolic process
ASZ81_02722	COG1758	RNA polymerase activity
ASZ81_02723	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASZ81_02724	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASZ81_02725	COG2233	PERMEase
ASZ81_02727	COG0745	RESPONSE REGULATOR receiver
ASZ81_02728	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASZ81_02729	COG2183	response to ionizing radiation
ASZ81_02731	COG0596	Alpha beta hydrolase
ASZ81_02733	COG1040	competence protein
ASZ81_02734	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ASZ81_02734	COG0316	Belongs to the HesB IscA family
ASZ81_02735	COG0494	nUDIX hydrolase
ASZ81_02736	COG1218	3'(2'),5'-bisphosphate nucleotidase
ASZ81_02738	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ASZ81_02739	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ASZ81_02740	COG3156	type II secretion system protein K
ASZ81_02741	COG4795	General secretion pathway protein
ASZ81_02742	COG2165	general secretion pathway protein
ASZ81_02743	COG2165	general secretion pathway protein
ASZ81_02744	COG2165	general secretion pathway protein
ASZ81_02745	COG1459	type II secretion system
ASZ81_02746	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASZ81_02748	COG3031	protein transport across the cell outer membrane
ASZ81_02749	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ASZ81_02750	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ASZ81_02751	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ASZ81_02753	COG0456	acetyltransferase
ASZ81_02754	COG1490	D-aminoacyl-tRNA deacylase activity
ASZ81_02759	COG0174	glutamine synthetase
ASZ81_02761	COG3852	Histidine kinase
ASZ81_02763	COG5001	Diguanylate cyclase
ASZ81_02763	COG3300	MHYT domain
ASZ81_02764	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ASZ81_02781	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ASZ81_02782	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASZ81_02783	COG1739	Uncharacterized protein family UPF0029
ASZ81_02784	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASZ81_02784	COG1024	Enoyl-CoA hydratase
ASZ81_02785	COG0183	Belongs to the thiolase family
ASZ81_02786	COG0583	DNA-binding transcription factor activity
ASZ81_02787	COG2814	Major facilitator Superfamily
ASZ81_02788	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASZ81_02789	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ASZ81_02790	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ASZ81_02791	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ASZ81_02792	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ASZ81_02793	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASZ81_02794	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ASZ81_02796	COG0356	it plays a direct role in the translocation of protons across the membrane
ASZ81_02797	COG3312	ion transport
ASZ81_02798	COG1475	DNA binding
ASZ81_02799	COG1192	Involved in chromosome partitioning
ASZ81_02800	COG0357	Ribosomal RNA small subunit methyltransferase G
ASZ81_02801	COG0445	tRNA wobble uridine modification
ASZ81_02816	COG0217	transcriptional regulatory protein
ASZ81_02817	COG2084	Dehydrogenase
ASZ81_02820	COG2909	trisaccharide binding
ASZ81_02821	COG0058	SHG alpha-glucan phosphorylase activity
ASZ81_02822	COG1640	4-alpha-glucanotransferase
ASZ81_02823	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ASZ81_02825	COG3501	Rhs element vgr protein
ASZ81_02832	COG0471	metal ion transport
ASZ81_02833	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ASZ81_02841	COG0671	phosphoesterase, PA-phosphatase related
ASZ81_02842	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ASZ81_02844	COG1999	signal sequence binding
ASZ81_02848	COG0786	glutamate:sodium symporter activity
ASZ81_02852	COG1566	PFAM secretion protein HlyD family protein
ASZ81_02854	COG3706	GGDEF domain
ASZ81_02857	COG0813	purine-nucleoside phosphorylase activity
ASZ81_02859	COG3272	Protein of unknown function (DUF1722)
ASZ81_02861	COG0415	Belongs to the DNA photolyase family
ASZ81_02862	COG1388	LysM domain
ASZ81_02862	COG1376	ErfK ybiS ycfS ynhG family protein
ASZ81_02865	COG0513	Belongs to the DEAD box helicase family
ASZ81_02866	COG1770	oligopeptidase
ASZ81_02872	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASZ81_02873	COG0573	inorganic phosphate transmembrane transporter activity
ASZ81_02874	COG0581	inorganic phosphate transmembrane transporter activity
ASZ81_02875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASZ81_02879	COG0659	secondary active sulfate transmembrane transporter activity
ASZ81_02881	COG0739	heme binding
ASZ81_02882	COG5001	Diguanylate cyclase
ASZ81_02882	COG3300	MHYT domain
ASZ81_02883	COG0583	DNA-binding transcription factor activity
ASZ81_02884	COG2814	Major facilitator Superfamily
ASZ81_02889	COG1301	dicarboxylic acid transport
ASZ81_02892	COG1342	Belongs to the UPF0251 family
ASZ81_02899	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ASZ81_02900	COG0673	inositol 2-dehydrogenase activity
ASZ81_02902	COG2200	EAL domain
ASZ81_02902	COG2771	luxR family
ASZ81_02903	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASZ81_02905	COG0564	pseudouridine synthase activity
ASZ81_02924	COG3501	Rhs element vgr protein
ASZ81_02928	COG1869	D-ribose catabolic process
ASZ81_02929	COG1129	ABC transporter
ASZ81_02930	COG1172	Belongs to the binding-protein-dependent transport system permease family
ASZ81_02931	COG1879	ABC-type sugar transport system periplasmic component
ASZ81_02932	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASZ81_02933	COG1609	Transcriptional regulator
ASZ81_02935	COG3201	nicotinamide mononucleotide transporter
ASZ81_02936	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ASZ81_02938	COG0584	glycerophosphoryl diester phosphodiesterase
ASZ81_02939	COG2271	Major facilitator Superfamily
ASZ81_02948	COG0579	oxidoreductase
ASZ81_02950	COG0242	peptide deformylase activity
ASZ81_02952	COG1320	monovalent cation:proton antiporter activity
ASZ81_02953	COG2212	antiporter activity
ASZ81_02957	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASZ81_02957	COG2111	Na H antiporter
ASZ81_02959	COG0589	response to stress
ASZ81_02960	COG0814	amino acid
ASZ81_02961	COG3033	Beta-eliminating lyase
ASZ81_02965	COG3530	Putative quorum-sensing-regulated virulence factor
ASZ81_02967	COG5002	protein histidine kinase activity
ASZ81_02967	COG5001	Diguanylate cyclase
ASZ81_02968	COG1278	Cold shock
ASZ81_02972	COG2304	oxidoreductase activity
ASZ81_02976	COG0714	Associated with various cellular activities
ASZ81_02978	COG0840	transmembrane signaling receptor activity
ASZ81_02982	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASZ81_02984	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASZ81_02986	COG3604	Transcriptional regulator
ASZ81_02987	COG1017	nitric oxide dioxygenase activity
ASZ81_02987	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASZ81_02988	COG1278	Cold shock
ASZ81_02989	COG3036	rescue of stalled ribosome
ASZ81_02995	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ASZ81_02995	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ASZ81_02996	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASZ81_02999	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASZ81_03002	COG0516	GMP reductase activity
ASZ81_03007	COG1943	Transposase
ASZ81_03009	COG0513	Belongs to the DEAD box helicase family
ASZ81_03010	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ASZ81_03012	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ASZ81_03013	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ASZ81_03014	COG3437	response regulator, receiver
ASZ81_03014	COG0784	Response regulator, receiver
ASZ81_03015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASZ81_03015	COG4191	Histidine kinase
ASZ81_03017	COG1757	Na H antiporter
ASZ81_03018	COG2814	Major facilitator Superfamily
ASZ81_03021	COG3706	GGDEF domain
ASZ81_03022	COG3240	lipase activity
ASZ81_03025	COG0840	transmembrane signaling receptor activity
ASZ81_03026	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ASZ81_03027	COG5380	lipid catabolic process
ASZ81_03028	COG3291	Pkd domain containing protein
ASZ81_03028	COG4412	M6 family metalloprotease domain protein
ASZ81_03032	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASZ81_03033	COG4605	iron ion homeostasis
ASZ81_03034	COG4604	ABC transporter, ATP-binding protein
ASZ81_03038	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASZ81_03042	COG0745	RESPONSE REGULATOR receiver
ASZ81_03044	COG3623	hexulose-6-phosphate isomerase
ASZ81_03045	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ASZ81_03046	COG0561	phosphatase activity
ASZ81_03052	COG3038	cytochrome b561
ASZ81_03053	COG0366	Alpha amylase catalytic
ASZ81_03059	COG0745	RESPONSE REGULATOR receiver
ASZ81_03060	COG5002	protein histidine kinase activity
ASZ81_03067	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASZ81_03070	COG2814	Major facilitator Superfamily
ASZ81_03073	COG1686	Belongs to the peptidase S11 family
ASZ81_03079	COG1943	Transposase
ASZ81_03080	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASZ81_03080	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASZ81_03082	COG0509	glycine decarboxylation via glycine cleavage system
ASZ81_03083	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASZ81_03085	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ASZ81_03087	COG3039	Transposase
ASZ81_03092	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ASZ81_03094	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ASZ81_03095	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ASZ81_03102	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASZ81_03105	COG1028	Short-chain dehydrogenase reductase Sdr
ASZ81_03109	COG0346	lactoylglutathione lyase activity
ASZ81_03120	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASZ81_03150	COG1418	mRNA catabolic process
ASZ81_03169	COG1028	Short-chain dehydrogenase reductase Sdr
ASZ81_03170	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASZ81_03178	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ASZ81_03183	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASZ81_03184	COG0494	nUDIX hydrolase
ASZ81_03186	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ81_03188	COG3040	lipid binding
ASZ81_03193	COG3041	Addiction module toxin RelE StbE family
ASZ81_03207	COG1619	proteins homologs of microcin C7 resistance protein MccF
ASZ81_03209	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASZ81_03219	COG0346	lactoylglutathione lyase activity
ASZ81_03223	COG3040	lipid binding
ASZ81_03227	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASZ81_03228	COG1280	lysine exporter protein (LysE YggA)
ASZ81_03257	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASZ81_03261	COG3549	Plasmid maintenance system killer
ASZ81_03262	COG3093	addiction module antidote protein HigA
ASZ81_03264	COG0384	phenazine biosynthesis protein PhzF
ASZ81_03271	COG0346	lactoylglutathione lyase activity
ASZ81_03278	COG3040	lipid binding
ASZ81_03289	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ81_03293	COG0384	phenazine biosynthesis protein PhzF
ASZ81_03302	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASZ81_03306	COG0384	phenazine biosynthesis protein PhzF
ASZ81_03312	COG1619	proteins homologs of microcin C7 resistance protein MccF
ASZ81_03317	COG3040	lipid binding
ASZ81_03328	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ASZ81_03329	COG4977	sequence-specific DNA binding
ASZ81_03343	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ASZ81_03344	COG2944	sequence-specific DNA binding
ASZ81_03347	COG3039	Transposase
ASZ81_03348	COG0110	maltose O-acetyltransferase activity
ASZ81_03351	COG0346	lactoylglutathione lyase activity
ASZ81_03368	COG1943	Transposase
ASZ81_03379	COG0346	lactoylglutathione lyase activity
ASZ81_03384	COG1328	CTP reductase activity
ASZ81_03385	COG0602	queuosine metabolic process
ASZ81_03387	COG4067	protein conserved in archaea
ASZ81_03387	COG0189	ligase activity
ASZ81_03389	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ81_03389	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ASZ81_03389	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ81_03390	COG1105	Belongs to the carbohydrate kinase PfkB family
ASZ81_03391	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ81_03391	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ81_03392	COG1609	Transcriptional regulator
ASZ81_03393	COG0420	3'-5' exonuclease activity
ASZ81_03394	COG0419	ATPase involved in DNA repair
ASZ81_03395	COG0784	Response regulator, receiver
ASZ81_03395	COG2205	protein histidine kinase activity
ASZ81_03396	COG0156	8-amino-7-oxononanoate synthase activity
ASZ81_03398	COG0038	chloride channel
ASZ81_03399	COG0523	cobalamin synthesis protein
ASZ81_03401	COG3158	transport of potassium into the cell
ASZ81_03402	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASZ81_03402	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ASZ81_03402	COG0674	pyruvate-flavodoxin oxidoreductase activity
ASZ81_03402	COG1013	pyruvate-flavodoxin oxidoreductase activity
ASZ81_03403	COG2205	protein histidine kinase activity
ASZ81_03404	COG0745	RESPONSE REGULATOR receiver
ASZ81_03405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASZ81_03406	COG0586	Pfam SNARE associated Golgi protein
ASZ81_03408	COG2200	EAL domain
ASZ81_03410	COG3038	cytochrome b561
ASZ81_03412	COG2116	formate transmembrane transporter activity
ASZ81_03413	COG0583	DNA-binding transcription factor activity
ASZ81_03415	COG3593	DNA synthesis involved in DNA repair
ASZ81_03416	COG0737	Belongs to the 5'-nucleotidase family
ASZ81_03420	COG2824	Alkylphosphonate utilization operon protein PhnA
ASZ81_03431	COG3706	GGDEF domain
ASZ81_03434	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ASZ81_03435	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ASZ81_03437	COG0745	RESPONSE REGULATOR receiver
ASZ81_03441	COG0023	Translation Initiation Factor
ASZ81_03443	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASZ81_03445	COG1042	CoA-binding domain protein
ASZ81_03445	COG0045	succinate-CoA ligase (ADP-forming) activity
ASZ81_03445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ81_03446	COG0583	DNA-binding transcription factor activity
ASZ81_03447	COG1629	transport
ASZ81_03447	COG4771	TonB-dependent receptor
ASZ81_03451	COG2050	protein possibly involved in aromatic compounds catabolism
ASZ81_03456	COG0625	glutathione transferase activity
ASZ81_03459	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASZ81_03460	COG4172	Belongs to the ABC transporter superfamily
ASZ81_03461	COG4239	(ABC) transporter, permease
ASZ81_03462	COG4174	ABC transporter (Permease)
ASZ81_03463	COG4166	transmembrane transport
ASZ81_03472	COG3842	ATPase activity
ASZ81_03474	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ASZ81_03476	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASZ81_03477	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASZ81_03478	COG1011	Hydrolase
ASZ81_03480	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ASZ81_03483	COG1970	mechanosensitive ion channel activity
ASZ81_03485	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ASZ81_03486	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ81_03486	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ81_03487	COG0302	gtp cyclohydrolase
ASZ81_03489	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ASZ81_03491	COG2897	thiosulfate sulfurtransferase activity
ASZ81_03492	COG2390	Transcriptional regulator
ASZ81_03493	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASZ81_03494	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASZ81_03500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASZ81_03506	COG0583	DNA-binding transcription factor activity
ASZ81_03507	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ASZ81_03508	COG0778	Nitroreductase
ASZ81_03513	COG0640	Transcriptional regulator
ASZ81_03515	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASZ81_03524	COG1263	PTS System
ASZ81_03524	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ81_03526	COG1621	beta-fructofuranosidase activity
ASZ81_03527	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASZ81_03528	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ASZ81_03530	COG2885	chlorophyll binding
ASZ81_03531	COG0545	Peptidyl-prolyl cis-trans isomerase
ASZ81_03532	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASZ81_03533	COG0840	transmembrane signaling receptor activity
ASZ81_03534	COG3069	C4-dicarboxylate transmembrane transporter activity
ASZ81_03535	COG1760	l-serine dehydratase
ASZ81_03540	COG1609	Transcriptional regulator
ASZ81_03541	COG2197	response regulator
ASZ81_03542	COG3850	Histidine kinase
ASZ81_03543	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASZ81_03545	COG0243	molybdopterin cofactor binding
ASZ81_03549	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ASZ81_03550	COG2197	response regulator
ASZ81_03551	COG3851	Histidine kinase
ASZ81_03552	COG2271	Major facilitator Superfamily
ASZ81_03553	COG1840	ABC-type Fe3 transport system, periplasmic component
ASZ81_03555	COG3842	ATPase activity
ASZ81_03556	COG3243	poly(R)-hydroxyalkanoic acid synthase
ASZ81_03558	COG0183	Belongs to the thiolase family
ASZ81_03560	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASZ81_03561	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASZ81_03564	COG3706	GGDEF domain
ASZ81_03565	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ASZ81_03568	COG1979	alcohol dehydrogenase
ASZ81_03571	COG4191	Histidine kinase
ASZ81_03572	COG1840	ABC-type Fe3 transport system, periplasmic component
ASZ81_03574	COG2271	Major facilitator Superfamily
ASZ81_03575	COG0469	pyruvate kinase activity
ASZ81_03576	COG2205	protein histidine kinase activity
ASZ81_03576	COG0784	Response regulator, receiver
ASZ81_03576	COG2198	Histidine kinase
ASZ81_03577	COG1879	ABC-type sugar transport system periplasmic component
ASZ81_03578	COG1803	Methylglyoxal synthase
ASZ81_03579	COG1335	isochorismatase
ASZ81_03581	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ASZ81_03584	COG0210	DNA helicase
ASZ81_03585	COG1289	transmembrane transporter activity
ASZ81_03591	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ASZ81_03592	COG4149	molybdate abc transporter
ASZ81_03593	COG0725	ABC transporter, periplasmic molybdate-binding protein
ASZ81_03594	COG1492	cobalamin metabolic process
ASZ81_03604	COG5002	protein histidine kinase activity
ASZ81_03604	COG0784	Response regulator, receiver
ASZ81_03605	COG1879	ABC-type sugar transport system periplasmic component
ASZ81_03607	COG2827	Endonuclease containing a URI domain
ASZ81_03614	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ASZ81_03615	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ASZ81_03617	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ASZ81_03618	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
ASZ81_03619	COG0247	lactate metabolic process
ASZ81_03620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASZ81_03621	COG3118	belongs to the thioredoxin family
ASZ81_03628	COG0583	DNA-binding transcription factor activity
ASZ81_03629	COG4160	amino acid transport
ASZ81_03630	COG4215	(ABC) transporter
ASZ81_03631	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASZ81_03632	COG1126	abc transporter atp-binding protein
ASZ81_03634	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ASZ81_03636	COG0494	nUDIX hydrolase
ASZ81_03637	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ASZ81_03639	COG1309	transcriptional regulator
ASZ81_03640	COG0513	Belongs to the DEAD box helicase family
ASZ81_03641	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
ASZ81_03643	COG0814	amino acid
ASZ81_03644	COG0840	transmembrane signaling receptor activity
ASZ81_03646	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ASZ81_03647	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ASZ81_03649	COG1984	allophanate hydrolase subunit 2
ASZ81_03653	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ASZ81_03654	COG4181	ATPase activity
ASZ81_03656	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASZ81_03657	COG5001	Diguanylate cyclase
ASZ81_03657	COG1716	ATPase activity
ASZ81_03659	COG0484	heat shock protein binding
ASZ81_03668	COG0546	phosphoglycolate phosphatase activity
ASZ81_03671	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASZ81_03672	COG1368	sulfuric ester hydrolase activity
ASZ81_03674	COG0513	Belongs to the DEAD box helicase family
ASZ81_03675	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
ASZ81_03677	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASZ81_03679	COG3046	protein related to deoxyribodipyrimidine photolyase
ASZ81_03681	COG3397	chitin binding
ASZ81_03682	COG3227	Zinc metalloprotease (Elastase)
ASZ81_03684	COG0010	Belongs to the arginase family
ASZ81_03685	COG1166	arginine decarboxylase activity
ASZ81_03688	COG2239	Acts as a magnesium transporter
ASZ81_03689	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ASZ81_03690	COG0459	protein refolding
ASZ81_03692	COG0527	aspartate kinase activity
ASZ81_03693	COG0662	Cupin 2, conserved barrel domain protein
ASZ81_03694	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ASZ81_03695	COG0456	acetyltransferase
ASZ81_03697	COG2154	pterin-4-alpha-carbinolamine dehydratase
ASZ81_03698	COG3186	Phenylalanine-4-hydroxylase
ASZ81_03699	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASZ81_03702	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASZ81_03703	COG0583	DNA-binding transcription factor activity
ASZ81_03706	COG2171	N-acyltransferase activity
ASZ81_03707	COG1253	flavin adenine dinucleotide binding
ASZ81_03708	COG1765	OsmC-like protein
ASZ81_03716	COG0531	amino acid
ASZ81_03717	COG3706	GGDEF domain
ASZ81_03719	COG3279	Response regulator of the LytR AlgR family
ASZ81_03720	COG3275	phosphorelay sensor kinase activity
ASZ81_03723	COG1136	(ABC) transporter
ASZ81_03723	COG0577	efflux transmembrane transporter activity
ASZ81_03724	COG1136	(ABC) transporter
ASZ81_03728	COG4989	oxidoreductase activity
ASZ81_03729	COG0366	Alpha amylase catalytic
ASZ81_03732	COG2067	long-chain fatty acid transport protein
ASZ81_03733	COG2267	carboxylic ester hydrolase activity
ASZ81_03735	COG3227	Zinc metalloprotease (Elastase)
ASZ81_03736	COG3047	cAMP biosynthetic process
ASZ81_03738	COG1686	Belongs to the peptidase S11 family
ASZ81_03739	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASZ81_03741	COG1271	oxidase subunit
ASZ81_03742	COG1294	oxidase, subunit
ASZ81_03745	COG3048	D-serine ammonia-lyase activity
ASZ81_03746	COG0583	DNA-binding transcription factor activity
ASZ81_03754	COG1063	alcohol dehydrogenase
ASZ81_03756	COG0693	protein deglycase activity
ASZ81_03759	COG0346	lactoylglutathione lyase activity
ASZ81_03763	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ASZ81_03764	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ASZ81_03765	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ASZ81_03766	COG0363	glucosamine-6-phosphate deaminase activity
ASZ81_03767	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ASZ81_03772	COG1929	Belongs to the glycerate kinase type-1 family
ASZ81_03773	COG2610	gluconate transmembrane transporter activity
ASZ81_03774	COG3835	regulator
ASZ81_03776	COG0748	coenzyme F420 binding
ASZ81_03777	COG3721	Heme iron utilization protein
ASZ81_03779	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ASZ81_03780	COG0811	peptide transport
ASZ81_03781	COG0848	biopolymer transport protein
ASZ81_03782	COG4558	Periplasmic binding protein
ASZ81_03783	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASZ81_03784	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ASZ81_03791	COG3217	Mosc domain protein beta barrel domain protein
ASZ81_03791	COG0633	Ferredoxin
ASZ81_03791	COG3217	Mosc domain protein beta barrel domain protein
ASZ81_03791	COG0633	Ferredoxin
ASZ81_03792	COG0418	dihydroorotase activity
ASZ81_03794	COG3152	Membrane
ASZ81_03796	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASZ81_03797	COG2354	Protein conserved in bacteria
ASZ81_03798	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ASZ81_03799	COG1278	Cold shock
ASZ81_03803	COG4753	response regulator
ASZ81_03803	COG2207	Transcriptional regulator
ASZ81_03805	COG3706	GGDEF domain
ASZ81_03806	COG1349	DNA-binding transcription factor activity
ASZ81_03809	COG3833	ABC-type maltose transport systems, permease component
ASZ81_03810	COG1175	transmembrane transport
ASZ81_03812	COG3842	ATPase activity
ASZ81_03813	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ81_03816	COG0393	Putative heavy-metal-binding
ASZ81_03817	COG2197	response regulator
ASZ81_03818	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASZ81_03819	COG0835	chemotaxis
ASZ81_03819	COG0784	Response regulator, receiver
ASZ81_03820	COG1846	Transcriptional regulator
ASZ81_03821	COG3706	GGDEF domain
ASZ81_03829	COG0583	DNA-binding transcription factor activity
ASZ81_03830	COG5001	Diguanylate cyclase
ASZ81_03832	COG1741	Belongs to the pirin family
ASZ81_03833	COG3123	guanosine phosphorylase activity
ASZ81_03835	COG2211	Major facilitator Superfamily
ASZ81_03837	COG0840	transmembrane signaling receptor activity
ASZ81_03839	COG1067	ATP-dependent peptidase activity
ASZ81_03841	COG4172	Belongs to the ABC transporter superfamily
ASZ81_03845	COG0583	DNA-binding transcription factor activity
ASZ81_03847	COG1620	l-lactate permease
ASZ81_03848	COG1304	FMN binding
ASZ81_03850	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ASZ81_03852	COG0840	transmembrane signaling receptor activity
ASZ81_03854	COG0513	Belongs to the DEAD box helicase family
ASZ81_03856	COG0583	DNA-binding transcription factor activity
ASZ81_03858	COG1902	pentaerythritol trinitrate reductase activity
ASZ81_03860	COG1132	(ABC) transporter
ASZ81_03862	COG1902	pentaerythritol trinitrate reductase activity
ASZ81_03864	COG1280	lysine exporter protein (LysE YggA)
ASZ81_03865	COG2207	Transcriptional regulator
ASZ81_03869	COG1846	Transcriptional regulator
ASZ81_03870	COG1764	response to oxidative stress
ASZ81_03871	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASZ81_03873	COG0697	spore germination
ASZ81_03875	COG0700	Nucleoside recognition
ASZ81_03876	COG3366	ferrous iron transmembrane transporter activity
ASZ81_03877	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ASZ81_03879	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASZ81_03880	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ASZ81_03881	COG2259	Doxx family
ASZ81_03886	COG0363	glucosamine-6-phosphate deaminase activity
ASZ81_03889	COG4580	involved in the transport of maltose and maltodextrins
ASZ81_03892	COG0840	transmembrane signaling receptor activity
ASZ81_03895	COG0840	transmembrane signaling receptor activity
ASZ81_03897	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASZ81_03898	COG1126	abc transporter atp-binding protein
ASZ81_03900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASZ81_03901	COG4597	amino acid ABC transporter
ASZ81_03902	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASZ81_03904	COG0739	heme binding
ASZ81_03906	COG2213	PTS system mannitol-specific
ASZ81_03906	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ81_03907	COG0246	Mannitol dehydrogenase
ASZ81_03908	COG3722	fumarate hydratase activity
ASZ81_03909	COG0673	inositol 2-dehydrogenase activity
ASZ81_03915	COG2910	NAD(P)H-binding
ASZ81_03917	COG0840	transmembrane signaling receptor activity
ASZ81_03918	COG4221	oxidoreductase activity
ASZ81_03920	COG1901	pseudouridine methyltransferase
ASZ81_03921	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASZ81_03923	COG0531	amino acid
ASZ81_03924	COG1982	Orn Lys Arg decarboxylase major
ASZ81_03931	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASZ81_03937	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ASZ81_03939	COG0259	pyridoxamine-phosphate oxidase activity
ASZ81_03945	COG0745	RESPONSE REGULATOR receiver
ASZ81_03949	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ASZ81_03950	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASZ81_03951	COG0840	transmembrane signaling receptor activity
ASZ81_03952	COG0835	chemotaxis
ASZ81_03953	COG0835	chemotaxis
ASZ81_03954	COG0643	Histidine kinase
ASZ81_03954	COG2198	Histidine kinase
ASZ81_03958	COG0601	transmembrane transport
ASZ81_03959	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASZ81_03961	COG2194	sulfuric ester hydrolase activity
ASZ81_03962	COG0642	Histidine kinase
ASZ81_03963	COG0745	RESPONSE REGULATOR receiver
ASZ81_03969	COG1444	tRNA N-acetyltransferase activity
ASZ81_03970	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
