locus-tag	class	description
ASZ88_00006	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ASZ88_00007	COG1404	Belongs to the peptidase S8 family
ASZ88_00008	COG4206	TonB-dependent receptor
ASZ88_00009	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASZ88_00012	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASZ88_00013	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASZ88_00014	COG2177	Part of the ABC transporter FtsEX involved in
ASZ88_00015	COG2884	Cell division ATP-binding protein ftsE
ASZ88_00016	COG0552	protein localization to endoplasmic reticulum
ASZ88_00017	COG0742	ribosomal rna small subunit methyltransferase
ASZ88_00022	COG0783	Belongs to the Dps family
ASZ88_00023	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ASZ88_00024	COG1280	lysine exporter protein (LysE YggA)
ASZ88_00025	COG2267	carboxylic ester hydrolase activity
ASZ88_00026	COG0561	phosphatase activity
ASZ88_00029	COG2199	diguanylate cyclase activity
ASZ88_00029	COG2200	EAL domain
ASZ88_00029	COG3287	FIST C domain
ASZ88_00030	COG1011	Hydrolase
ASZ88_00031	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ASZ88_00033	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ASZ88_00034	COG0019	diaminopimelate decarboxylase activity
ASZ88_00035	COG1965	Belongs to the frataxin family
ASZ88_00036	COG3072	Adenylate cyclase
ASZ88_00037	COG0181	hydroxymethylbilane synthase activity
ASZ88_00038	COG1587	Uroporphyrinogen-III synthase
ASZ88_00039	COG2959	enzyme of heme biosynthesis
ASZ88_00040	COG3071	HemY protein
ASZ88_00041	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASZ88_00043	COG3078	GTPase activator activity
ASZ88_00046	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ASZ88_00047	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASZ88_00047	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASZ88_00050	COG0084	hydrolase, TatD family'
ASZ88_00051	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASZ88_00053	COG0840	transmembrane signaling receptor activity
ASZ88_00054	COG1580	Controls the rotational direction of flagella during chemotaxis
ASZ88_00055	COG3161	chorismate lyase activity
ASZ88_00056	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ASZ88_00057	COG2937	Belongs to the GPAT DAPAT family
ASZ88_00058	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ASZ88_00060	COG0534	Mate efflux family protein
ASZ88_00061	COG1858	cytochrome C peroxidase
ASZ88_00062	COG0805	protein transport
ASZ88_00063	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASZ88_00064	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASZ88_00065	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASZ88_00067	COG2226	methyltransferase
ASZ88_00068	COG1322	Protein conserved in bacteria
ASZ88_00070	COG2081	HI0933 family
ASZ88_00072	COG1528	Iron-storage protein
ASZ88_00073	COG0589	response to stress
ASZ88_00074	COG0697	spore germination
ASZ88_00076	COG0742	ribosomal rna small subunit methyltransferase
ASZ88_00077	COG5002	protein histidine kinase activity
ASZ88_00077	COG5001	Diguanylate cyclase
ASZ88_00078	COG1522	sequence-specific DNA binding
ASZ88_00082	COG0006	proline dipeptidase activity
ASZ88_00082	COG0006	proline dipeptidase activity
ASZ88_00083	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ASZ88_00084	COG2022	thiamine diphosphate biosynthetic process
ASZ88_00085	COG2104	thiamine diphosphate biosynthetic process
ASZ88_00086	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ASZ88_00088	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ASZ88_00089	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASZ88_00096	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ASZ88_00098	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASZ88_00099	COG0408	coproporphyrinogen oxidase activity
ASZ88_00100	COG0009	L-threonylcarbamoyladenylate synthase
ASZ88_00101	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ASZ88_00102	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ASZ88_00103	COG0551	DNA topoisomerase type I activity
ASZ88_00104	COG2922	Belongs to the Smg family
ASZ88_00105	COG0758	DNA mediated transformation
ASZ88_00106	COG1652	LysM domain
ASZ88_00107	COG0242	peptide deformylase activity
ASZ88_00108	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ASZ88_00109	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASZ88_00109	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ASZ88_00110	COG0569	domain protein
ASZ88_00111	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASZ88_00113	COG1272	protein, Hemolysin III
ASZ88_00114	COG4326	sporulation control protein
ASZ88_00115	COG3084	Protein conserved in bacteria
ASZ88_00117	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ASZ88_00118	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASZ88_00119	COG0204	Acyl-transferase
ASZ88_00120	COG0606	chelatase, subunit chli
ASZ88_00128	COG5433	transposase activity
ASZ88_00138	COG0606	chelatase, subunit chli
ASZ88_00141	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASZ88_00142	COG0129	dihydroxy-acid dehydratase activity
ASZ88_00144	COG0604	alcohol dehydrogenase
ASZ88_00146	COG0425	Belongs to the sulfur carrier protein TusA family
ASZ88_00148	COG2119	membrane
ASZ88_00149	COG0752	glycyl-tRNA synthetase alpha subunit
ASZ88_00150	COG0751	glycine-tRNA ligase activity
ASZ88_00151	COG3977	Valine--pyruvate aminotransferase
ASZ88_00152	COG0071	Belongs to the small heat shock protein (HSP20) family
ASZ88_00155	COG0187	DNA topoisomerase II activity
ASZ88_00156	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ASZ88_00157	COG0592	DNA-directed DNA polymerase activity
ASZ88_00158	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASZ88_00161	COG1126	abc transporter atp-binding protein
ASZ88_00162	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ASZ88_00163	COG0594	ribonuclease P activity
ASZ88_00164	COG0706	membrane insertase activity
ASZ88_00165	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ASZ88_00166	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ASZ88_00167	COG0445	tRNA wobble uridine modification
ASZ88_00168	COG0357	Ribosomal RNA small subunit methyltransferase G
ASZ88_00169	COG1192	Involved in chromosome partitioning
ASZ88_00170	COG1475	DNA binding
ASZ88_00171	COG3312	ion transport
ASZ88_00172	COG0356	it plays a direct role in the translocation of protons across the membrane
ASZ88_00174	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ASZ88_00175	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASZ88_00176	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ASZ88_00177	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ASZ88_00178	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ASZ88_00179	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ASZ88_00180	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASZ88_00181	COG2814	Major facilitator Superfamily
ASZ88_00182	COG0583	DNA-binding transcription factor activity
ASZ88_00183	COG0183	Belongs to the thiolase family
ASZ88_00184	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASZ88_00184	COG1024	Enoyl-CoA hydratase
ASZ88_00185	COG1739	Uncharacterized protein family UPF0029
ASZ88_00186	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASZ88_00187	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ASZ88_00200	COG0583	DNA-binding transcription factor activity
ASZ88_00201	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ASZ88_00202	COG2960	long-chain fatty acid transporting porin activity
ASZ88_00203	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASZ88_00204	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ88_00205	COG1309	transcriptional regulator
ASZ88_00214	COG0747	negative chemotaxis
ASZ88_00216	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASZ88_00218	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASZ88_00219	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ASZ88_00221	COG0210	DNA helicase
ASZ88_00222	COG1280	lysine exporter protein (LysE YggA)
ASZ88_00225	COG2962	Rard protein
ASZ88_00226	COG0514	ATP-dependent DNA helicase (RecQ)
ASZ88_00229	COG1132	(ABC) transporter
ASZ88_00230	COG4774	siderophore transport
ASZ88_00231	COG1120	ATPase activity
ASZ88_00235	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ASZ88_00236	COG1263	PTS System
ASZ88_00236	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ88_00238	COG1561	YicC-like family, N-terminal region
ASZ88_00239	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ASZ88_00240	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ASZ88_00241	COG1560	Kdo2-lipid A biosynthetic process
ASZ88_00242	COG1560	Kdo2-lipid A biosynthetic process
ASZ88_00243	COG1309	transcriptional regulator
ASZ88_00244	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ASZ88_00247	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASZ88_00248	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ASZ88_00250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ASZ88_00251	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ASZ88_00252	COG0859	PFAM glycosyl transferase family 9
ASZ88_00253	COG0463	Glycosyl transferase, family 2
ASZ88_00254	COG0859	PFAM glycosyl transferase family 9
ASZ88_00255	COG3642	lipopolysaccharide core region biosynthetic process
ASZ88_00261	COG1519	Transferase
ASZ88_00268	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASZ88_00269	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ASZ88_00269	COG0662	Cupin 2, conserved barrel domain protein
ASZ88_00270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASZ88_00271	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ASZ88_00277	COG0318	PFAM AMP-dependent synthetase and ligase
ASZ88_00278	COG1012	belongs to the aldehyde dehydrogenase family
ASZ88_00278	COG1454	alcohol dehydrogenase
ASZ88_00281	COG5433	transposase activity
ASZ88_00282	COG5433	transposase activity
ASZ88_00287	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASZ88_00288	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ASZ88_00289	COG0668	transmembrane transport
ASZ88_00290	COG1573	uracil-dna glycosylase
ASZ88_00292	COG3068	Protein conserved in bacteria
ASZ88_00294	COG1940	carbohydrate kinase activity
ASZ88_00295	COG1253	flavin adenine dinucleotide binding
ASZ88_00296	COG0776	regulation of translation
ASZ88_00298	COG0151	Belongs to the GarS family
ASZ88_00299	COG0138	bifunctional purine biosynthesis protein purh
ASZ88_00300	COG0789	Transcriptional regulator
ASZ88_00301	COG3710	Transcriptional regulator
ASZ88_00302	COG0531	amino acid
ASZ88_00303	COG1982	Orn Lys Arg decarboxylase major
ASZ88_00304	COG0840	transmembrane signaling receptor activity
ASZ88_00307	COG0800	Aldolase
ASZ88_00309	COG3265	gluconokinase activity
ASZ88_00310	COG0129	dihydroxy-acid dehydratase activity
ASZ88_00311	COG1609	Transcriptional regulator
ASZ88_00312	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ASZ88_00313	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASZ88_00315	COG0439	Biotin carboxylase
ASZ88_00316	COG0511	ligase activity, forming carbon-carbon bonds
ASZ88_00317	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ASZ88_00318	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASZ88_00321	COG2814	Major facilitator Superfamily
ASZ88_00322	COG2205	protein histidine kinase activity
ASZ88_00322	COG0784	Response regulator, receiver
ASZ88_00323	COG0248	Ppx GppA phosphatase
ASZ88_00324	COG0513	Belongs to the DEAD box helicase family
ASZ88_00325	COG3118	belongs to the thioredoxin family
ASZ88_00326	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ASZ88_00328	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASZ88_00337	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASZ88_00339	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ASZ88_00341	COG1072	(Pantothenic acid kinase))
ASZ88_00346	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASZ88_00347	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASZ88_00348	COG0250	Participates in transcription elongation, termination and antitermination
ASZ88_00349	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ASZ88_00350	COG0081	regulation of translation
ASZ88_00351	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ASZ88_00352	COG0222	ribosome binding
ASZ88_00353	COG0085	RNA polymerase activity
ASZ88_00354	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ASZ88_00355	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
ASZ88_00356	COG2816	NAD+ diphosphatase activity
ASZ88_00357	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ASZ88_00360	COG4942	peptidase
ASZ88_00361	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ASZ88_00363	COG0471	metal ion transport
ASZ88_00364	COG0688	phosphatidylethanolamine metabolic process
ASZ88_00365	COG1162	GTPase activity
ASZ88_00366	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ASZ88_00375	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ASZ88_00376	COG0802	atpase or kinase
ASZ88_00378	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ASZ88_00379	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ASZ88_00380	COG1923	regulation of RNA biosynthetic process
ASZ88_00381	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ASZ88_00382	COG0330	HflC and HflK could
ASZ88_00383	COG0330	HflC and HflK could
ASZ88_00384	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ASZ88_00385	COG2900	Belongs to the SlyX family
ASZ88_00387	COG0545	Peptidyl-prolyl cis-trans isomerase
ASZ88_00388	COG2964	Protein conserved in bacteria
ASZ88_00389	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ASZ88_00390	COG2923	Belongs to the DsrF TusC family
ASZ88_00392	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ASZ88_00393	COG0049	tRNA binding
ASZ88_00394	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASZ88_00395	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASZ88_00396	COG2906	2 iron, 2 sulfur cluster binding
ASZ88_00398	COG0360	Binds together with S18 to 16S ribosomal RNA
ASZ88_00399	COG2965	DNA replication, synthesis of RNA primer
ASZ88_00400	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ASZ88_00401	COG0359	binds to the 23S rRNA
ASZ88_00403	COG0305	Participates in initiation and elongation during chromosome replication
ASZ88_00404	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASZ88_00405	COG0432	Pfam Uncharacterised protein family UPF0047
ASZ88_00406	COG0166	Belongs to the GPI family
ASZ88_00409	COG0735	belongs to the Fur family
ASZ88_00410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASZ88_00414	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ASZ88_00415	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASZ88_00416	COG0175	sulfate reduction
ASZ88_00430	COG1410	methionine synthase
ASZ88_00430	COG0646	methionine synthase
ASZ88_00431	COG0527	aspartate kinase activity
ASZ88_00432	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ASZ88_00434	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ASZ88_00437	COG0629	single-stranded DNA binding
ASZ88_00438	COG2200	EAL domain
ASZ88_00438	COG2199	diguanylate cyclase activity
ASZ88_00443	COG3409	Peptidoglycan-binding domain 1 protein
ASZ88_00443	COG3267	Type II secretory pathway component ExeA
ASZ88_00445	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASZ88_00446	COG1459	type II secretion system
ASZ88_00455	COG1077	Cell shape determining protein MreB Mrl
ASZ88_00456	COG1792	Involved in formation and maintenance of cell shape
ASZ88_00457	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ASZ88_00458	COG0424	maF-like protein
ASZ88_00459	COG1530	ribonuclease E activity
ASZ88_00460	COG3164	Protein of unknown function
ASZ88_00461	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASZ88_00462	COG0312	modulator of DNA gyrase
ASZ88_00463	COG2235	arginine
ASZ88_00467	COG0589	response to stress
ASZ88_00470	COG1438	arginine binding
ASZ88_00471	COG0039	L-malate dehydrogenase activity
ASZ88_00472	COG0531	amino acid
ASZ88_00473	COG0142	geranyltranstransferase activity
ASZ88_00474	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ASZ88_00475	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ASZ88_00476	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ASZ88_00477	COG2966	Psort location CytoplasmicMembrane, score
ASZ88_00478	COG3610	response to peptide
ASZ88_00480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASZ88_00481	COG2967	ApaG domain
ASZ88_00482	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ASZ88_00483	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ASZ88_00484	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASZ88_00485	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ASZ88_00486	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASZ88_00497	COG0741	lytic transglycosylase activity
ASZ88_00498	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ASZ88_00499	COG1194	a g-specific adenine glycosylase
ASZ88_00500	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASZ88_00501	COG2066	Belongs to the glutaminase family
ASZ88_00502	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASZ88_00503	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ASZ88_00506	COG0762	integral membrane protein
ASZ88_00507	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ASZ88_00508	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ASZ88_00512	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASZ88_00513	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ASZ88_00514	COG1678	Uncharacterized ACR, COG1678
ASZ88_00515	COG0189	ligase activity
ASZ88_00516	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASZ88_00517	COG2356	endonuclease I
ASZ88_00518	COG3091	SprT-like family
ASZ88_00519	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ASZ88_00520	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASZ88_00521	COG0583	DNA-binding transcription factor activity
ASZ88_00522	COG4771	TonB-dependent receptor
ASZ88_00523	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASZ88_00524	COG0126	phosphoglycerate kinase activity
ASZ88_00525	COG0191	fructose-bisphosphate aldolase activity
ASZ88_00526	COG0668	transmembrane transport
ASZ88_00527	COG1279	arginine transmembrane transporter activity
ASZ88_00528	COG0583	DNA-binding transcription factor activity
ASZ88_00530	COG0469	pyruvate kinase activity
ASZ88_00531	COG1349	DNA-binding transcription factor activity
ASZ88_00532	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ASZ88_00533	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASZ88_00536	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASZ88_00537	COG0358	DNA primase activity
ASZ88_00538	COG1610	YqeY-like protein
ASZ88_00539	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ASZ88_00540	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ASZ88_00542	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASZ88_00543	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ASZ88_00544	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ASZ88_00545	COG1968	undecaprenyl-diphosphatase activity
ASZ88_00546	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ASZ88_00547	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ASZ88_00548	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ASZ88_00549	COG0585	pseudouridine synthase activity
ASZ88_00550	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ASZ88_00551	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ASZ88_00552	COG1388	LysM domain
ASZ88_00552	COG4942	peptidase
ASZ88_00553	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASZ88_00554	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ASZ88_00558	COG4208	sulfate ABC transporter
ASZ88_00559	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ASZ88_00561	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ASZ88_00562	COG2137	regulation of response to DNA damage stimulus
ASZ88_00563	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ASZ88_00564	COG0527	aspartate kinase activity
ASZ88_00565	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ASZ88_00574	COG3630	sodium ion export across plasma membrane
ASZ88_00575	COG5016	pyruvate
ASZ88_00575	COG0511	ligase activity, forming carbon-carbon bonds
ASZ88_00576	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ASZ88_00578	COG1238	metal cluster binding
ASZ88_00579	COG0612	Peptidase, M16
ASZ88_00580	COG2918	glutathione biosynthetic process
ASZ88_00581	COG1854	S-ribosylhomocysteine lyase activity
ASZ88_00582	COG4536	flavin adenine dinucleotide binding
ASZ88_00583	COG4137	Cytochrome C assembly protein
ASZ88_00584	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ASZ88_00585	COG0228	four-way junction DNA binding
ASZ88_00586	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ASZ88_00587	COG0336	Belongs to the RNA methyltransferase TrmD family
ASZ88_00588	COG0335	large ribosomal subunit rRNA binding
ASZ88_00589	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASZ88_00590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASZ88_00592	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ASZ88_00593	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ASZ88_00594	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ASZ88_00595	COG0723	plastoquinol--plastocyanin reductase activity
ASZ88_00596	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ASZ88_00597	COG2857	Cytochrome c1
ASZ88_00598	COG0625	glutathione transferase activity
ASZ88_00599	COG2969	positive regulation of protein catabolic process
ASZ88_00600	COG2823	Periplasmic or secreted lipoprotein
ASZ88_00601	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ASZ88_00602	COG0792	nuclease activity
ASZ88_00603	COG3107	peptidoglycan biosynthetic process
ASZ88_00604	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ASZ88_00607	COG0288	reversible hydration of carbon dioxide
ASZ88_00608	COG0659	secondary active sulfate transmembrane transporter activity
ASZ88_00609	COG1131	(ABC) transporter
ASZ88_00610	COG0842	Transport permease protein
ASZ88_00611	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ASZ88_00612	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ASZ88_00613	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ASZ88_00615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASZ88_00616	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ASZ88_00617	COG1489	DNA binding
ASZ88_00619	COG1643	Atp-dependent helicase
ASZ88_00620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASZ88_00621	COG1752	Esterase of the alpha-beta hydrolase superfamily
ASZ88_00622	COG1049	propionate catabolic process, 2-methylcitrate cycle
ASZ88_00623	COG3112	Uncharacterised protein family (UPF0231)
ASZ88_00624	COG0347	Belongs to the P(II) protein family
ASZ88_00625	COG0004	ammonium transporteR
ASZ88_00626	COG1840	ABC-type Fe3 transport system, periplasmic component
ASZ88_00628	COG3842	ATPase activity
ASZ88_00632	COG2971	BadF BadG BcrA BcrD
ASZ88_00634	COG4608	Belongs to the ABC transporter superfamily
ASZ88_00635	COG0444	Belongs to the ABC transporter superfamily
ASZ88_00636	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASZ88_00637	COG0601	transmembrane transport
ASZ88_00638	COG0747	negative chemotaxis
ASZ88_00640	COG2813	Specifically methylates the guanine in position
ASZ88_00641	COG0628	permease
ASZ88_00643	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ASZ88_00644	COG0316	Belongs to the HesB IscA family
ASZ88_00647	COG0739	heme binding
ASZ88_00648	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASZ88_00649	COG2027	D-alanyl-D-alanine carboxypeptidase
ASZ88_00650	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASZ88_00651	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASZ88_00652	COG1534	Rna-binding protein
ASZ88_00653	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ASZ88_00654	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASZ88_00655	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ASZ88_00656	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASZ88_00658	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASZ88_00661	COG0779	Required for maturation of 30S ribosomal subunits
ASZ88_00662	COG0195	Participates in both transcription termination and antitermination
ASZ88_00663	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ASZ88_00664	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASZ88_00665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ASZ88_00666	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ASZ88_00667	COG1185	polyribonucleotide nucleotidyltransferase activity
ASZ88_00668	COG4785	May be involved in cell division
ASZ88_00675	COG3153	acetyltransferase
ASZ88_00679	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ASZ88_00680	COG0513	Belongs to the DEAD box helicase family
ASZ88_00681	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ASZ88_00683	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ASZ88_00684	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASZ88_00685	COG2204	response regulator
ASZ88_00687	COG0667	Aldo Keto reductase
ASZ88_00688	COG3066	DNA modification
ASZ88_00689	COG0494	nUDIX hydrolase
ASZ88_00690	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ASZ88_00691	COG0730	response to heat
ASZ88_00692	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ASZ88_00693	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ASZ88_00694	COG1283	sodium-dependent phosphate transmembrane transporter activity
ASZ88_00695	COG0583	DNA-binding transcription factor activity
ASZ88_00696	COG0640	Transcriptional regulator
ASZ88_00697	COG0268	Binds directly to 16S ribosomal RNA
ASZ88_00698	COG0728	peptidoglycan biosynthetic process
ASZ88_00699	COG0196	riboflavin kinase activity
ASZ88_00700	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ASZ88_00701	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ASZ88_00702	COG1047	Peptidyl-prolyl cis-trans
ASZ88_00703	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ASZ88_00704	COG1966	Carbon starvation protein
ASZ88_00707	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ASZ88_00708	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ASZ88_00709	COG1472	Belongs to the glycosyl hydrolase 3 family
ASZ88_00710	COG3279	Response regulator of the LytR AlgR family
ASZ88_00711	COG3275	phosphorelay sensor kinase activity
ASZ88_00712	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASZ88_00713	COG0287	Prephenate dehydrogenase
ASZ88_00713	COG1605	Chorismate mutase
ASZ88_00715	COG0488	(ABC) transporter
ASZ88_00717	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
ASZ88_00718	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
ASZ88_00719	COG5001	Diguanylate cyclase
ASZ88_00720	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASZ88_00721	COG0077	Prephenate dehydratase
ASZ88_00721	COG1605	Chorismate mutase
ASZ88_00722	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ASZ88_00723	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASZ88_00724	COG0564	pseudouridine synthase activity
ASZ88_00726	COG0542	response to heat
ASZ88_00734	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASZ88_00736	COG2974	May be involved in recombination
ASZ88_00737	COG0745	RESPONSE REGULATOR receiver
ASZ88_00738	COG5002	protein histidine kinase activity
ASZ88_00740	COG0248	Ppx GppA phosphatase
ASZ88_00741	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ASZ88_00743	COG0581	inorganic phosphate transmembrane transporter activity
ASZ88_00744	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASZ88_00747	COG3142	Participates in the control of copper homeostasis
ASZ88_00748	COG0450	alkyl hydroperoxide reductase
ASZ88_00749	COG0583	DNA-binding transcription factor activity
ASZ88_00750	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ASZ88_00752	COG0517	IMP dehydrogenase activity
ASZ88_00753	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ASZ88_00754	COG0343	queuine tRNA-ribosyltransferase activity
ASZ88_00755	COG1862	Preprotein translocase
ASZ88_00756	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASZ88_00757	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASZ88_00758	COG0483	inositol monophosphate 1-phosphatase activity
ASZ88_00760	COG1959	2 iron, 2 sulfur cluster binding
ASZ88_00761	COG1104	cysteine desulfurase activity
ASZ88_00762	COG0822	iron-sulfur transferase activity
ASZ88_00764	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASZ88_00765	COG0443	Heat shock 70 kDa protein
ASZ88_00766	COG0633	Ferredoxin
ASZ88_00767	COG2975	iron-sulfur cluster assembly
ASZ88_00768	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASZ88_00769	COG0105	UTP biosynthetic process
ASZ88_00770	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ASZ88_00772	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ASZ88_00773	COG0124	histidyl-tRNA synthetase
ASZ88_00774	COG2976	Protein conserved in bacteria
ASZ88_00775	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASZ88_00776	COG1160	GTP binding
ASZ88_00779	COG1570	exodeoxyribonuclease VII activity
ASZ88_00780	COG0516	GMP reductase activity
ASZ88_00780	COG0517	IMP dehydrogenase activity
ASZ88_00781	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASZ88_00781	COG0519	Catalyzes the synthesis of GMP from XMP
ASZ88_00783	COG1584	GPR1 FUN34 yaaH family protein
ASZ88_00784	COG3433	isochorismatase activity
ASZ88_00784	COG1535	isochorismatase
ASZ88_00785	COG1021	2,3-dihydroxybenzoate-AMP ligase
ASZ88_00786	COG1169	isochorismate synthase
ASZ88_00787	COG1028	Short-chain dehydrogenase reductase Sdr
ASZ88_00789	COG4592	Periplasmic binding protein
ASZ88_00790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASZ88_00791	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASZ88_00792	COG1120	ATPase activity
ASZ88_00794	COG0583	DNA-binding transcription factor activity
ASZ88_00795	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ASZ88_00796	COG1115	amino acid carrier protein
ASZ88_00797	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASZ88_00798	COG0583	DNA-binding transcription factor activity
ASZ88_00801	COG4565	transcriptional regulatory protein
ASZ88_00803	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ASZ88_00804	COG5016	pyruvate
ASZ88_00804	COG0511	ligase activity, forming carbon-carbon bonds
ASZ88_00805	COG3630	sodium ion export across plasma membrane
ASZ88_00807	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ASZ88_00808	COG3052	prosthetic group binding
ASZ88_00809	COG2301	Belongs to the HpcH HpaI aldolase family
ASZ88_00810	COG3051	citrate lyase alpha subunit
ASZ88_00811	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
ASZ88_00812	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ASZ88_00814	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASZ88_00815	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ASZ88_00816	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ASZ88_00827	COG1012	belongs to the aldehyde dehydrogenase family
ASZ88_00831	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ASZ88_00832	COG0840	transmembrane signaling receptor activity
ASZ88_00833	COG3710	Transcriptional regulator
ASZ88_00835	COG2165	general secretion pathway protein
ASZ88_00838	COG4796	Type ii and iii secretion system protein
ASZ88_00842	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASZ88_00843	COG1459	type II secretion system
ASZ88_00845	COG2207	Transcriptional regulator
ASZ88_00846	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ASZ88_00851	COG0739	heme binding
ASZ88_00853	COG3064	Membrane
ASZ88_00854	COG0582	viral genome integration into host DNA
ASZ88_00856	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ASZ88_00857	COG2867	negative regulation of translational initiation
ASZ88_00858	COG2914	Belongs to the UPF0125 (RnfH) family
ASZ88_00859	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASZ88_00860	COG0497	DNA recombination
ASZ88_00861	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ASZ88_00862	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ASZ88_00863	COG0443	Heat shock 70 kDa protein
ASZ88_00864	COG0484	heat shock protein binding
ASZ88_00870	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ASZ88_00871	COG0590	tRNA wobble adenosine to inosine editing
ASZ88_00873	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ASZ88_00874	COG0047	phosphoribosylformylglycinamidine synthase activity
ASZ88_00874	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASZ88_00875	COG1943	Transposase
ASZ88_00879	COG0442	prolyl-tRNA aminoacylation
ASZ88_00880	COG1720	tRNA m6t6A37 methyltransferase activity
ASZ88_00881	COG0254	rRNA binding
ASZ88_00882	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ASZ88_00883	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ASZ88_00884	COG1671	Belongs to the UPF0178 family
ASZ88_00886	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ88_00889	COG3098	single-species biofilm formation
ASZ88_00890	COG0564	pseudouridine synthase activity
ASZ88_00891	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ASZ88_00892	COG0142	geranyltranstransferase activity
ASZ88_00893	COG1722	exodeoxyribonuclease VII activity
ASZ88_00894	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ASZ88_00896	COG0301	tRNA thio-modification
ASZ88_00896	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASZ88_00897	COG0583	DNA-binding transcription factor activity
ASZ88_00898	COG2363	Small membrane protein
ASZ88_00899	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASZ88_00900	COG1611	Belongs to the LOG family
ASZ88_00901	COG3706	GGDEF domain
ASZ88_00903	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASZ88_00903	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASZ88_00905	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
ASZ88_00906	COG1464	Belongs to the NlpA lipoprotein family
ASZ88_00907	COG2011	ABC-type metal ion transport system permease component
ASZ88_00908	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASZ88_00909	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASZ88_00910	COG1609	Transcriptional regulator
ASZ88_00911	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ88_00911	COG1263	PTS System
ASZ88_00912	COG0366	Alpha amylase catalytic
ASZ88_00918	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASZ88_00921	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ASZ88_00922	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ASZ88_00923	COG0110	maltose O-acetyltransferase activity
ASZ88_00927	COG1045	serine acetyltransferase
ASZ88_00929	COG0438	transferase activity, transferring glycosyl groups
ASZ88_00931	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ASZ88_00937	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASZ88_00939	COG1596	polysaccharide export
ASZ88_00944	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASZ88_00946	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ASZ88_00947	COG0321	lipoyl(octanoyl) transferase activity
ASZ88_00948	COG2921	Belongs to the UPF0250 family
ASZ88_00949	COG1686	Belongs to the peptidase S11 family
ASZ88_00950	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ASZ88_00951	COG0772	Belongs to the SEDS family
ASZ88_00952	COG0768	penicillin binding
ASZ88_00953	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ASZ88_00954	COG0799	negative regulation of ribosome biogenesis
ASZ88_00955	COG1466	dna polymerase III delta subunit
ASZ88_00956	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ASZ88_00957	COG0495	leucyl-tRNA aminoacylation
ASZ88_00958	COG2888	peptidyl-tyrosine sulfation
ASZ88_00959	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ASZ88_00960	COG4535	Mg2 and Co2 transporter CorC
ASZ88_00961	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ASZ88_00962	COG1702	phosphate starvation-inducible protein PhoH
ASZ88_00963	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASZ88_00964	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASZ88_00965	COG2190	(PTS) system
ASZ88_00967	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ88_00968	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ASZ88_00969	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ASZ88_00970	COG3115	cell septum assembly
ASZ88_00971	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASZ88_00974	COG0789	Transcriptional regulator
ASZ88_00975	COG1585	Membrane protein implicated in regulation of membrane protease activity
ASZ88_00976	COG0330	HflC and HflK could
ASZ88_00977	COG3118	belongs to the thioredoxin family
ASZ88_00978	COG0300	oxidoreductase activity
ASZ88_00979	COG1090	epimerase
ASZ88_00980	COG0622	Phosphoesterase
ASZ88_00983	COG3710	Transcriptional regulator
ASZ88_00984	COG0326	Molecular chaperone. Has ATPase activity
ASZ88_00985	COG0563	adenylate kinase activity
ASZ88_00986	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ASZ88_00989	COG0367	asparagine synthase
ASZ88_00990	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASZ88_00990	COG4651	solute:proton antiporter activity
ASZ88_00991	COG1846	Transcriptional regulator
ASZ88_00991	COG1940	carbohydrate kinase activity
ASZ88_00992	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ASZ88_00993	COG2190	(PTS) system
ASZ88_00993	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ88_00993	COG1263	PTS System
ASZ88_00994	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASZ88_00996	COG0101	tRNA pseudouridine synthase activity
ASZ88_00997	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ASZ88_00998	COG0285	dihydrofolate synthase activity
ASZ88_00999	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ASZ88_01000	COG1286	toxin biosynthetic process
ASZ88_01001	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ASZ88_01002	COG2056	Na+-H+ antiporter family
ASZ88_01003	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASZ88_01006	COG0346	lactoylglutathione lyase activity
ASZ88_01007	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ASZ88_01008	COG4660	Part of a membrane complex involved in electron transport
ASZ88_01009	COG4659	FMN binding
ASZ88_01010	COG4658	electron transport chain
ASZ88_01011	COG4656	Part of a membrane complex involved in electron transport
ASZ88_01012	COG2878	Part of a membrane complex involved in electron transport
ASZ88_01013	COG4657	Part of a membrane complex involved in electron transport
ASZ88_01015	COG0556	nucleotide-excision repair
ASZ88_01016	COG2204	response regulator
ASZ88_01017	COG2198	Histidine kinase
ASZ88_01018	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ASZ88_01019	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ASZ88_01020	COG0521	Mo-molybdopterin cofactor biosynthetic process
ASZ88_01021	COG0315	cyclic pyranopterin monophosphate synthase activity
ASZ88_01022	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ASZ88_01023	COG0314	molybdopterin synthase activity
ASZ88_01024	COG2199	diguanylate cyclase activity
ASZ88_01025	COG4109	DRTGG domain
ASZ88_01027	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ASZ88_01029	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASZ88_01029	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASZ88_01030	COG0489	protein tyrosine kinase activity
ASZ88_01031	COG0572	uridine kinase
ASZ88_01032	COG2982	Protein involved in outer membrane biogenesis
ASZ88_01033	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ASZ88_01034	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASZ88_01036	COG2067	long-chain fatty acid transport protein
ASZ88_01039	COG0183	Belongs to the thiolase family
ASZ88_01040	COG1024	Enoyl-CoA hydratase
ASZ88_01040	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASZ88_01041	COG0778	Nitroreductase
ASZ88_01042	COG0583	DNA-binding transcription factor activity
ASZ88_01043	COG0745	RESPONSE REGULATOR receiver
ASZ88_01045	COG2832	Protein of unknown function (DUF454)
ASZ88_01046	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASZ88_01048	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ASZ88_01049	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ASZ88_01052	COG1028	Short-chain dehydrogenase reductase Sdr
ASZ88_01053	COG0616	signal peptide processing
ASZ88_01055	COG1522	sequence-specific DNA binding
ASZ88_01056	COG1946	Acyl-CoA thioesterase
ASZ88_01060	COG3706	GGDEF domain
ASZ88_01061	COG0640	Transcriptional regulator
ASZ88_01062	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASZ88_01067	COG1881	PFAM PEBP family protein
ASZ88_01070	COG0009	L-threonylcarbamoyladenylate synthase
ASZ88_01073	COG2201	protein-glutamate methylesterase activity
ASZ88_01075	COG5002	protein histidine kinase activity
ASZ88_01076	COG4191	Histidine kinase
ASZ88_01077	COG5001	Diguanylate cyclase
ASZ88_01077	COG3300	MHYT domain
ASZ88_01078	COG2204	response regulator
ASZ88_01082	COG0601	transmembrane transport
ASZ88_01083	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASZ88_01084	COG0444	Belongs to the ABC transporter superfamily
ASZ88_01085	COG4608	Belongs to the ABC transporter superfamily
ASZ88_01086	COG0435	Glutathione S-transferase
ASZ88_01087	COG0280	phosphate acetyltransferase
ASZ88_01087	COG0857	belongs to the CobB CobQ family
ASZ88_01088	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASZ88_01089	COG3092	negative regulation of chromosome organization
ASZ88_01090	COG4628	conserved protein (DUF2132)
ASZ88_01092	COG4120	Belongs to the binding-protein-dependent transport system permease family
ASZ88_01094	COG2203	Gaf domain
ASZ88_01094	COG2199	diguanylate cyclase activity
ASZ88_01095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASZ88_01097	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ASZ88_01098	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASZ88_01099	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ASZ88_01100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASZ88_01101	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ASZ88_01102	COG0156	8-amino-7-oxononanoate synthase activity
ASZ88_01103	COG2226	methyltransferase
ASZ88_01104	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ASZ88_01106	COG0501	Belongs to the peptidase M48B family
ASZ88_01108	COG0300	oxidoreductase activity
ASZ88_01111	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASZ88_01113	COG2268	Band 7 protein
ASZ88_01115	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASZ88_01116	COG2915	High frequency lysogenization protein hflD homolog
ASZ88_01117	COG0482	sulfurtransferase activity
ASZ88_01118	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASZ88_01119	COG2916	Histone family protein nucleoid-structuring protein H-NS
ASZ88_01120	COG1757	Na H antiporter
ASZ88_01121	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ASZ88_01122	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ASZ88_01123	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASZ88_01124	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASZ88_01124	COG0131	Imidazoleglycerol-phosphate dehydratase
ASZ88_01125	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ASZ88_01126	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ASZ88_01127	COG0107	imidazoleglycerol-phosphate synthase activity
ASZ88_01128	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ASZ88_01128	COG0140	phosphoribosyl-ATP diphosphatase activity
ASZ88_01129	COG1187	pseudouridine synthase activity
ASZ88_01131	COG1278	Cold shock
ASZ88_01132	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ASZ88_01133	COG0542	response to heat
ASZ88_01135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASZ88_01136	COG1012	belongs to the aldehyde dehydrogenase family
ASZ88_01136	COG1454	alcohol dehydrogenase
ASZ88_01137	COG1737	Transcriptional regulator
ASZ88_01138	COG0076	glutamate decarboxylase activity
ASZ88_01140	COG2431	L-lysine efflux transmembrane transporter activity
ASZ88_01142	COG3070	regulator of competence-specific genes
ASZ88_01145	COG3852	Histidine kinase
ASZ88_01147	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ASZ88_01150	COG4067	protein conserved in archaea
ASZ88_01150	COG0189	ligase activity
ASZ88_01151	COG0500	methyltransferase
ASZ88_01152	COG4106	trans-aconitate 2-methyltransferase activity
ASZ88_01153	COG1801	Protein of unknown function DUF72
ASZ88_01154	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ASZ88_01155	COG1435	thymidine kinase activity
ASZ88_01157	COG0159	tryptophan synthase activity
ASZ88_01158	COG0133	tryptophan synthase activity
ASZ88_01159	COG0135	phosphoribosylanthranilate isomerase activity
ASZ88_01159	COG0134	indole-3-glycerol-phosphate synthase activity
ASZ88_01160	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASZ88_01161	COG0512	Glutamine amidotransferase of anthranilate synthase
ASZ88_01162	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASZ88_01163	COG0613	PHP domain protein
ASZ88_01164	COG0009	L-threonylcarbamoyladenylate synthase
ASZ88_01165	COG1187	pseudouridine synthase activity
ASZ88_01166	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ASZ88_01167	COG4988	ABC transporter
ASZ88_01168	COG0492	ferredoxin-NADP+ reductase activity
ASZ88_01170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASZ88_01171	COG3706	GGDEF domain
ASZ88_01172	COG2949	membrane
ASZ88_01174	COG0281	malic enzyme
ASZ88_01176	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ASZ88_01180	COG2885	chlorophyll binding
ASZ88_01183	COG0247	lactate metabolic process
ASZ88_01183	COG0277	FAD linked oxidase domain protein
ASZ88_01187	COG2986	histidine ammonia-lyase
ASZ88_01188	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ASZ88_01189	COG0010	Belongs to the arginase family
ASZ88_01190	COG1228	amidohydrolase
ASZ88_01194	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASZ88_01196	COG5001	Diguanylate cyclase
ASZ88_01197	COG0417	DNA replication proofreading
ASZ88_01198	COG2197	response regulator
ASZ88_01199	COG0322	excinuclease ABC activity
ASZ88_01205	COG0745	RESPONSE REGULATOR receiver
ASZ88_01205	COG3706	GGDEF domain
ASZ88_01207	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ASZ88_01208	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASZ88_01208	COG0072	phenylalanine-tRNA ligase activity
ASZ88_01209	COG0776	regulation of translation
ASZ88_01212	COG0500	methyltransferase
ASZ88_01213	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ASZ88_01215	COG0295	cytidine deaminase activity
ASZ88_01216	COG1346	cytolysis
ASZ88_01218	COG2925	Exonuclease
ASZ88_01220	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ88_01221	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ASZ88_01222	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ASZ88_01225	COG2988	succinylglutamate desuccinylase activity
ASZ88_01226	COG4139	cobalamin transport
ASZ88_01227	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
ASZ88_01236	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASZ88_01237	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASZ88_01238	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASZ88_01242	COG2814	Major facilitator Superfamily
ASZ88_01244	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASZ88_01249	COG2989	Protein conserved in bacteria
ASZ88_01250	COG3108	Peptidase M15
ASZ88_01251	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASZ88_01254	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASZ88_01259	COG1846	Transcriptional regulator
ASZ88_01260	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASZ88_01261	COG0726	polysaccharide deacetylase
ASZ88_01262	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASZ88_01264	COG1447	Phosphotransferase system cellobiose-specific component IIA
ASZ88_01265	COG1486	melibiose metabolic process
ASZ88_01266	COG3394	polysaccharide catabolic process
ASZ88_01267	COG1609	Transcriptional regulator
ASZ88_01268	COG2943	transferase activity, transferring hexosyl groups
ASZ88_01269	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ASZ88_01270	COG0840	transmembrane signaling receptor activity
ASZ88_01273	COG1448	Aminotransferase
ASZ88_01274	COG2770	Histidine kinase
ASZ88_01274	COG3437	response regulator, receiver
ASZ88_01275	COG0351	phosphomethylpyrimidine kinase
ASZ88_01276	COG0017	Asparaginyl-tRNA synthetase
ASZ88_01277	COG0840	transmembrane signaling receptor activity
ASZ88_01278	COG0720	synthase
ASZ88_01279	COG1760	l-serine dehydratase
ASZ88_01280	COG0814	amino acid
ASZ88_01281	COG0494	nUDIX hydrolase
ASZ88_01282	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASZ88_01285	COG3106	COG3106 Predicted ATPase
ASZ88_01286	COG3768	UPF0283 membrane protein
ASZ88_01287	COG3283	Transcriptional regulator of aromatic amino acids metabolism
ASZ88_01288	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ88_01291	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASZ88_01293	COG0471	metal ion transport
ASZ88_01294	COG4191	Histidine kinase
ASZ88_01294	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASZ88_01296	COG2990	Protein conserved in bacteria
ASZ88_01297	COG3713	MltA-interacting MipA family protein
ASZ88_01298	COG2205	protein histidine kinase activity
ASZ88_01299	COG0745	RESPONSE REGULATOR receiver
ASZ88_01304	COG1129	ABC transporter
ASZ88_01311	COG2186	Transcriptional regulator
ASZ88_01312	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ASZ88_01313	COG0372	Belongs to the citrate synthase family
ASZ88_01320	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASZ88_01322	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ASZ88_01324	COG0625	glutathione transferase activity
ASZ88_01325	COG3437	response regulator, receiver
ASZ88_01326	COG4999	Histidine kinase
ASZ88_01326	COG3850	Histidine kinase
ASZ88_01326	COG3437	response regulator, receiver
ASZ88_01326	COG2205	protein histidine kinase activity
ASZ88_01328	COG3706	GGDEF domain
ASZ88_01329	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ASZ88_01330	COG1254	Belongs to the acylphosphatase family
ASZ88_01331	COG2920	part of a sulfur-relay system
ASZ88_01332	COG0670	Belongs to the BI1 family
ASZ88_01333	COG1126	abc transporter atp-binding protein
ASZ88_01334	COG0765	amino acid transport
ASZ88_01335	COG4597	amino acid ABC transporter
ASZ88_01336	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASZ88_01338	COG0561	phosphatase activity
ASZ88_01340	COG0602	queuosine metabolic process
ASZ88_01341	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ASZ88_01347	COG3706	GGDEF domain
ASZ88_01348	COG0443	Heat shock 70 kDa protein
ASZ88_01349	COG0443	Heat shock 70 kDa protein
ASZ88_01356	COG1643	Atp-dependent helicase
ASZ88_01358	COG0443	Heat shock 70 kDa protein
ASZ88_01359	COG0095	Lipoate-protein ligase
ASZ88_01360	COG0583	DNA-binding transcription factor activity
ASZ88_01361	COG0477	Major facilitator Superfamily
ASZ88_01362	COG0415	Belongs to the DNA photolyase family
ASZ88_01363	COG2076	Multidrug Resistance protein
ASZ88_01367	COG2198	Histidine kinase
ASZ88_01367	COG0643	Histidine kinase
ASZ88_01369	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASZ88_01371	COG2201	protein-glutamate methylesterase activity
ASZ88_01372	COG0835	chemotaxis
ASZ88_01373	COG0840	transmembrane signaling receptor activity
ASZ88_01373	COG3290	protein histidine kinase activity
ASZ88_01374	COG0840	transmembrane signaling receptor activity
ASZ88_01376	COG0513	Belongs to the DEAD box helicase family
ASZ88_01378	COG1538	Outer membrane efflux protein
ASZ88_01379	COG1566	PFAM secretion protein HlyD family protein
ASZ88_01380	COG2814	Major facilitator Superfamily
ASZ88_01381	COG0840	transmembrane signaling receptor activity
ASZ88_01382	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ASZ88_01384	COG3501	Rhs element vgr protein
ASZ88_01389	COG1280	lysine exporter protein (LysE YggA)
ASZ88_01390	COG1115	amino acid carrier protein
ASZ88_01393	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASZ88_01394	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASZ88_01395	COG1177	transmembrane transport
ASZ88_01396	COG1176	ABC-type spermidine putrescine transport system, permease component I
ASZ88_01397	COG3842	ATPase activity
ASZ88_01401	COG0037	tRNA processing
ASZ88_01402	COG0589	response to stress
ASZ88_01403	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASZ88_01406	COG2217	Heavy metal translocating P-type atpase
ASZ88_01408	COG2010	Cytochrome c
ASZ88_01411	COG3278	Belongs to the heme-copper respiratory oxidase family
ASZ88_01414	COG0784	Response regulator, receiver
ASZ88_01414	COG2205	protein histidine kinase activity
ASZ88_01419	COG2994	toxin metabolic process
ASZ88_01420	COG1073	alpha beta
ASZ88_01420	COG3064	Membrane
ASZ88_01420	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ASZ88_01437	COG3120	sequence-specific DNA binding
ASZ88_01438	COG1067	ATP-dependent peptidase activity
ASZ88_01439	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASZ88_01444	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ASZ88_01444	COG0116	Belongs to the methyltransferase superfamily
ASZ88_01447	COG0167	dihydroorotate dehydrogenase activity
ASZ88_01450	COG0308	aminopeptidase N
ASZ88_01453	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
ASZ88_01454	COG1956	GAF domain-containing protein
ASZ88_01455	COG1132	(ABC) transporter
ASZ88_01456	COG2995	paraquat-inducible protein a
ASZ88_01457	COG3008	intermembrane lipid transfer
ASZ88_01458	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ASZ88_01458	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ASZ88_01459	COG2996	Protein conserved in bacteria
ASZ88_01462	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASZ88_01464	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ASZ88_01467	COG0437	4 iron, 4 sulfur cluster binding
ASZ88_01468	COG0243	molybdopterin cofactor binding
ASZ88_01468	COG3383	formate dehydrogenase (NAD+) activity
ASZ88_01474	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ASZ88_01475	COG0488	(ABC) transporter
ASZ88_01476	COG3852	Histidine kinase
ASZ88_01477	COG2204	response regulator
ASZ88_01479	COG4662	Binding-protein-dependent transport system inner membrane component
ASZ88_01480	COG3842	ATPase activity
ASZ88_01481	COG0746	molybdenum cofactor guanylyltransferase activity
ASZ88_01486	COG1940	carbohydrate kinase activity
ASZ88_01489	COG0840	transmembrane signaling receptor activity
ASZ88_01490	COG0791	NLP P60 protein
ASZ88_01494	COG0534	Mate efflux family protein
ASZ88_01496	COG1793	dna ligase
ASZ88_01498	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ASZ88_01499	COG0848	biopolymer transport protein
ASZ88_01500	COG0811	peptide transport
ASZ88_01501	COG0811	peptide transport
ASZ88_01504	COG1175	transmembrane transport
ASZ88_01505	COG0395	ABC-type sugar transport system, permease component
ASZ88_01506	COG3842	ATPase activity
ASZ88_01507	COG1349	DNA-binding transcription factor activity
ASZ88_01508	COG0584	glycerophosphoryl diester phosphodiesterase
ASZ88_01509	COG2731	YhcH YjgK YiaL family protein
ASZ88_01510	COG0251	oxidation-reduction process
ASZ88_01511	COG1609	Transcriptional regulator
ASZ88_01512	COG2723	6-phospho-beta-galactosidase activity
ASZ88_01513	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ASZ88_01514	COG0583	DNA-binding transcription factor activity
ASZ88_01518	COG0577	efflux transmembrane transporter activity
ASZ88_01518	COG1136	(ABC) transporter
ASZ88_01519	COG1136	(ABC) transporter
ASZ88_01519	COG0577	efflux transmembrane transporter activity
ASZ88_01520	COG1136	(ABC) transporter
ASZ88_01520	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASZ88_01521	COG1294	oxidase, subunit
ASZ88_01522	COG1271	oxidase subunit
ASZ88_01530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASZ88_01532	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASZ88_01536	COG0753	catalase activity
ASZ88_01539	COG3527	Alpha-acetolactate decarboxylase
ASZ88_01542	COG2199	diguanylate cyclase activity
ASZ88_01542	COG2200	EAL domain
ASZ88_01543	COG3706	GGDEF domain
ASZ88_01544	COG2017	converts alpha-aldose to the beta-anomer
ASZ88_01545	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ASZ88_01546	COG1085	galactose-1-phosphate uridylyltransferase
ASZ88_01551	COG3706	GGDEF domain
ASZ88_01551	COG0745	RESPONSE REGULATOR receiver
ASZ88_01554	COG0835	chemotaxis
ASZ88_01554	COG0784	Response regulator, receiver
ASZ88_01556	COG4565	transcriptional regulatory protein
ASZ88_01557	COG3290	protein histidine kinase activity
ASZ88_01560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ88_01564	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ASZ88_01565	COG3063	Type IV pilus biogenesis stability protein PilW
ASZ88_01568	COG1451	nucleotide metabolic process
ASZ88_01570	COG0583	DNA-binding transcription factor activity
ASZ88_01574	COG1538	Outer membrane efflux protein
ASZ88_01576	COG0019	diaminopimelate decarboxylase activity
ASZ88_01577	COG1748	Saccharopine dehydrogenase
ASZ88_01579	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASZ88_01582	COG4181	ATPase activity
ASZ88_01583	COG0534	Mate efflux family protein
ASZ88_01584	COG0702	epimerase
ASZ88_01586	COG2814	Major facilitator Superfamily
ASZ88_01587	COG1187	pseudouridine synthase activity
ASZ88_01588	COG1061	Type III restriction enzyme res subunit
ASZ88_01592	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ASZ88_01593	COG5001	Diguanylate cyclase
ASZ88_01593	COG2203	Gaf domain
ASZ88_01593	COG4251	negative regulation of phosphorylation
ASZ88_01593	COG3706	GGDEF domain
ASZ88_01595	COG0840	transmembrane signaling receptor activity
ASZ88_01601	COG4934	collagen metabolic process
ASZ88_01605	COG2239	Acts as a magnesium transporter
ASZ88_01607	COG0814	amino acid
ASZ88_01608	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ88_01609	COG1131	(ABC) transporter
ASZ88_01610	COG0842	Transport permease protein
ASZ88_01612	COG3313	Fe-S protein
ASZ88_01614	COG4134	Bacterial extracellular solute-binding protein
ASZ88_01615	COG4135	transport system, permease component
ASZ88_01616	COG4136	ATPase activity
ASZ88_01617	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASZ88_01618	COG0564	pseudouridine synthase activity
ASZ88_01619	COG0733	neurotransmitter:sodium symporter activity
ASZ88_01621	COG0626	cystathionine gamma-synthase activity
ASZ88_01622	COG2818	Glycosylase
ASZ88_01625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ88_01628	COG1842	Phage shock protein A
ASZ88_01629	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ASZ88_01631	COG4168	peptide transport system, permease
ASZ88_01632	COG4171	peptide transport system, permease
ASZ88_01634	COG4172	Belongs to the ABC transporter superfamily
ASZ88_01637	COG1227	inorganic diphosphatase activity
ASZ88_01641	COG0243	molybdopterin cofactor binding
ASZ88_01642	COG3005	denitrification pathway
ASZ88_01643	COG4459	periplasmic nitrate reductase
ASZ88_01644	COG2116	formate transmembrane transporter activity
ASZ88_01646	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASZ88_01647	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ASZ88_01649	COG2917	probably involved in intracellular septation
ASZ88_01650	COG1607	acyl-coa hydrolase
ASZ88_01651	COG2350	Protein conserved in bacteria
ASZ88_01653	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ASZ88_01654	COG0583	DNA-binding transcription factor activity
ASZ88_01657	COG0612	Peptidase, M16
ASZ88_01659	COG1032	radical SAM domain protein
ASZ88_01662	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ASZ88_01663	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ASZ88_01664	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
ASZ88_01665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASZ88_01666	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ASZ88_01667	COG0745	RESPONSE REGULATOR receiver
ASZ88_01669	COG1609	Transcriptional regulator
ASZ88_01670	COG3070	regulator of competence-specific genes
ASZ88_01674	COG0297	glycogen (starch) synthase activity
ASZ88_01675	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ASZ88_01676	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASZ88_01678	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ASZ88_01679	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ASZ88_01680	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ASZ88_01681	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASZ88_01682	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASZ88_01687	COG1012	belongs to the aldehyde dehydrogenase family
ASZ88_01688	COG1309	transcriptional regulator
ASZ88_01692	COG0668	transmembrane transport
ASZ88_01693	COG2995	paraquat-inducible protein a
ASZ88_01694	COG3008	intermembrane lipid transfer
ASZ88_01694	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ASZ88_01696	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ88_01699	COG0582	viral genome integration into host DNA
ASZ88_01700	COG0582	viral genome integration into host DNA
ASZ88_01701	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASZ88_01705	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ASZ88_01709	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ASZ88_01713	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ASZ88_01714	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ASZ88_01715	COG1737	Transcriptional regulator
ASZ88_01716	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASZ88_01717	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASZ88_01718	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASZ88_01719	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASZ88_01720	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ASZ88_01721	COG1940	carbohydrate kinase activity
ASZ88_01722	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ASZ88_01723	COG4409	exo-alpha-(2->6)-sialidase activity
ASZ88_01725	COG2003	Belongs to the UPF0758 family
ASZ88_01730	COG3941	tape measure
ASZ88_01738	COG0488	(ABC) transporter
ASZ88_01754	COG0415	Belongs to the DNA photolyase family
ASZ88_01756	COG4628	conserved protein (DUF2132)
ASZ88_01757	COG3284	Transcriptional regulator
ASZ88_01758	COG1012	belongs to the aldehyde dehydrogenase family
ASZ88_01760	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ88_01761	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ88_01762	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ88_01764	COG2207	Transcriptional regulator
ASZ88_01765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ88_01765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ88_01765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ88_01766	COG1482	cell wall glycoprotein biosynthetic process
ASZ88_01768	COG5002	protein histidine kinase activity
ASZ88_01768	COG0784	Response regulator, receiver
ASZ88_01770	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ASZ88_01772	COG2885	chlorophyll binding
ASZ88_01773	COG0823	Involved in the tonB-independent uptake of proteins
ASZ88_01776	COG0811	peptide transport
ASZ88_01777	COG0824	Thioesterase
ASZ88_01778	COG4890	Cyd operon protein YbgT
ASZ88_01779	COG1294	oxidase, subunit
ASZ88_01780	COG1271	oxidase subunit
ASZ88_01782	COG2255	four-way junction helicase activity
ASZ88_01783	COG0632	four-way junction helicase activity
ASZ88_01784	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ASZ88_01785	COG0215	cysteine-tRNA ligase activity
ASZ88_01786	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ASZ88_01787	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASZ88_01788	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ASZ88_01790	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ASZ88_01791	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASZ88_01792	COG1199	ATP-dependent helicase activity
ASZ88_01793	COG0730	response to heat
ASZ88_01794	COG3923	Primosomal replication protein n
ASZ88_01796	COG0840	transmembrane signaling receptor activity
ASZ88_01797	COG0708	Exodeoxyribonuclease III
ASZ88_01798	COG4160	amino acid transport
ASZ88_01799	COG4215	(ABC) transporter
ASZ88_01804	COG1882	Formate acetyltransferase
ASZ88_01806	COG0840	transmembrane signaling receptor activity
ASZ88_01807	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ASZ88_01809	COG3013	Belongs to the UPF0304 family
ASZ88_01810	COG2766	serine protein kinase
ASZ88_01811	COG2718	Belongs to the UPF0229 family
ASZ88_01812	COG2719	SpoVR family
ASZ88_01813	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ASZ88_01815	COG1663	tetraacyldisaccharide 4'-kinase activity
ASZ88_01816	COG1132	(ABC) transporter
ASZ88_01817	COG2333	competence protein COMEC
ASZ88_01817	COG0658	competence protein
ASZ88_01819	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASZ88_01820	COG1136	(ABC) transporter
ASZ88_01821	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASZ88_01823	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ASZ88_01827	COG1252	NADH dehydrogenase
ASZ88_01833	COG0537	adenosine 5'-monophosphoramidase activity
ASZ88_01836	COG2186	Transcriptional regulator
ASZ88_01837	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASZ88_01838	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ASZ88_01839	COG1674	ftsk spoiiie
ASZ88_01841	COG0686	Belongs to the AlaDH PNT family
ASZ88_01843	COG0583	DNA-binding transcription factor activity
ASZ88_01846	COG0284	orotidine-5'-phosphate decarboxylase activity
ASZ88_01847	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ASZ88_01848	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ASZ88_01849	COG0776	regulation of translation
ASZ88_01850	COG0539	negative regulation of cytoplasmic translation
ASZ88_01851	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ASZ88_01852	COG1555	photosystem II stabilization
ASZ88_01853	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASZ88_01854	COG0776	regulation of translation
ASZ88_01855	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ASZ88_01856	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASZ88_01858	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASZ88_01859	COG4191	Histidine kinase
ASZ88_01861	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASZ88_01862	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASZ88_01863	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASZ88_01864	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ASZ88_01867	COG5001	Diguanylate cyclase
ASZ88_01867	COG3300	MHYT domain
ASZ88_01869	COG4589	Belongs to the CDS family
ASZ88_01876	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASZ88_01878	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASZ88_01882	COG0243	molybdopterin cofactor binding
ASZ88_01883	COG3005	denitrification pathway
ASZ88_01884	COG3469	chitinase activity
ASZ88_01884	COG3325	Belongs to the glycosyl hydrolase 18 family
ASZ88_01885	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASZ88_01887	COG2951	lytic endotransglycosylase activity
ASZ88_01888	COG3100	YcgL domain-containing protein
ASZ88_01889	COG0850	regulation of cytokinetic process
ASZ88_01890	COG2894	cell division
ASZ88_01891	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ASZ88_01892	COG3015	lipoprotein NlpE involved in copper resistance
ASZ88_01897	COG0477	Major facilitator Superfamily
ASZ88_01898	COG0840	transmembrane signaling receptor activity
ASZ88_01899	COG1396	sequence-specific DNA binding
ASZ88_01900	COG3135	benzoate transporter
ASZ88_01902	COG1441	menaquinone biosynthetic process
ASZ88_01904	COG0596	Alpha beta hydrolase
ASZ88_01905	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ASZ88_01906	COG1169	isochorismate synthase
ASZ88_01907	COG0436	Aminotransferase
ASZ88_01908	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ASZ88_01909	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ASZ88_01913	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ASZ88_01914	COG0318	PFAM AMP-dependent synthetase and ligase
ASZ88_01915	COG0596	Alpha beta hydrolase
ASZ88_01918	COG1214	PFAM Peptidase M22, glycoprotease
ASZ88_01919	COG1199	ATP-dependent helicase activity
ASZ88_01921	COG0788	formyltetrahydrofolate deformylase activity
ASZ88_01922	COG1902	pentaerythritol trinitrate reductase activity
ASZ88_01922	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASZ88_01923	COG0616	signal peptide processing
ASZ88_01924	COG0252	asparaginase activity
ASZ88_01925	COG3139	Protein of unknown function (DUF1315)
ASZ88_01927	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ88_01928	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASZ88_01929	COG0676	glucose-6-phosphate 1-epimerase activity
ASZ88_01931	COG2226	methyltransferase
ASZ88_01934	COG0835	chemotaxis
ASZ88_01934	COG0784	Response regulator, receiver
ASZ88_01935	COG1940	carbohydrate kinase activity
ASZ88_01937	COG4667	esterase of the alpha-beta hydrolase superfamily
ASZ88_01940	COG0733	neurotransmitter:sodium symporter activity
ASZ88_01942	COG1263	PTS System
ASZ88_01942	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ88_01943	COG0084	hydrolase, TatD family'
ASZ88_01945	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASZ88_01946	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ASZ88_01947	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASZ88_01948	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASZ88_01949	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASZ88_01950	COG1028	Short-chain dehydrogenase reductase Sdr
ASZ88_01951	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ASZ88_01952	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASZ88_01953	COG0416	fatty acid biosynthetic process
ASZ88_01954	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ASZ88_01955	COG1399	metal-binding, possibly nucleic acid-binding protein
ASZ88_01956	COG0424	maF-like protein
ASZ88_01957	COG0564	pseudouridine synthase activity
ASZ88_01958	COG1530	ribonuclease E activity
ASZ88_01959	COG0659	secondary active sulfate transmembrane transporter activity
ASZ88_01961	COG1454	alcohol dehydrogenase
ASZ88_01961	COG1012	belongs to the aldehyde dehydrogenase family
ASZ88_01962	COG2095	MarC family integral membrane protein
ASZ88_01963	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASZ88_01964	COG1757	Na H antiporter
ASZ88_01966	COG3081	Nucleoid-associated protein
ASZ88_01968	COG3083	sulfuric ester hydrolase activity
ASZ88_01971	COG0123	including yeast histone deacetylase and acetoin utilization protein
ASZ88_01972	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASZ88_01973	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ASZ88_01977	COG2853	Lipoprotein
ASZ88_01979	COG4235	cytochrome complex assembly
ASZ88_01979	COG3088	subunit of a heme lyase
ASZ88_01980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASZ88_01981	COG1138	Cytochrome C-type biogenesis protein
ASZ88_01982	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ASZ88_01984	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASZ88_01985	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASZ88_01986	COG4133	protoheme IX ABC transporter activity
ASZ88_01988	COG0835	chemotaxis
ASZ88_01990	COG1192	Involved in chromosome partitioning
ASZ88_01991	COG2201	protein-glutamate methylesterase activity
ASZ88_01992	COG2198	Histidine kinase
ASZ88_01992	COG0643	Histidine kinase
ASZ88_01993	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ASZ88_01996	COG0455	bacterial-type flagellum organization
ASZ88_01999	COG2062	phosphohistidine phosphatase, SixA
ASZ88_02000	COG1025	Belongs to the peptidase M16 family
ASZ88_02002	COG0018	arginyl-trna synthetase
ASZ88_02006	COG1918	ferrous iron import across plasma membrane
ASZ88_02007	COG4977	sequence-specific DNA binding
ASZ88_02008	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ASZ88_02009	COG1121	(ABC) transporter
ASZ88_02010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASZ88_02012	COG0045	succinate-CoA ligase (ADP-forming) activity
ASZ88_02013	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASZ88_02014	COG0567	Dehydrogenase, E1 component
ASZ88_02016	COG1053	succinate dehydrogenase
ASZ88_02017	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ASZ88_02018	COG2009	succinate dehydrogenase
ASZ88_02019	COG0372	Belongs to the citrate synthase family
ASZ88_02020	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ASZ88_02022	COG0033	Phosphoglucomutase
ASZ88_02023	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ASZ88_02024	COG0596	Alpha beta hydrolase
ASZ88_02027	COG1346	cytolysis
ASZ88_02029	COG0583	DNA-binding transcription factor activity
ASZ88_02031	COG0735	belongs to the Fur family
ASZ88_02032	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASZ88_02033	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASZ88_02034	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASZ88_02035	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ASZ88_02035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASZ88_02036	COG0431	NADPH-dependent FMN reductase
ASZ88_02038	COG3101	peptidyl-lysine hydroxylation
ASZ88_02039	COG2860	membrane
ASZ88_02040	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ASZ88_02041	COG2890	protein-(glutamine-N5) methyltransferase activity
ASZ88_02044	COG1684	flagellar biosynthetic protein fliR
ASZ88_02045	COG1987	bacterial-type flagellum assembly
ASZ88_02050	COG1580	Controls the rotational direction of flagella during chemotaxis
ASZ88_02054	COG1317	bacterial-type flagellum organization
ASZ88_02055	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASZ88_02057	COG1677	Flagellar hook-basal body complex protein FliE
ASZ88_02058	COG2204	response regulator
ASZ88_02059	COG4191	Histidine kinase
ASZ88_02060	COG2204	response regulator
ASZ88_02061	COG1516	flagellar protein fliS
ASZ88_02063	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ASZ88_02064	COG1334	flagellar protein FlaG
ASZ88_02065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ88_02066	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ88_02067	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ88_02068	COG2837	iron assimilation
ASZ88_02072	COG1393	Belongs to the ArsC family
ASZ88_02073	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASZ88_02074	COG1876	peptidase activity
ASZ88_02076	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ASZ88_02077	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASZ88_02079	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ASZ88_02083	COG4783	chaperone-mediated protein folding
ASZ88_02084	COG1393	Belongs to the ArsC family
ASZ88_02088	COG2233	PERMEase
ASZ88_02089	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ASZ88_02090	COG0737	Belongs to the 5'-nucleotidase family
ASZ88_02091	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ASZ88_02092	COG2912	Transglutaminase-like superfamily
ASZ88_02093	COG3094	Invasion gene expression up-regulator, SirB
ASZ88_02094	COG2890	protein-(glutamine-N5) methyltransferase activity
ASZ88_02095	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ASZ88_02096	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ASZ88_02097	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ASZ88_02098	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ASZ88_02099	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASZ88_02100	COG0193	aminoacyl-tRNA hydrolase activity
ASZ88_02101	COG0012	GTP binding
ASZ88_02118	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ88_02119	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ88_02122	COG3951	Flagellar rod assembly protein muramidase FlgJ
ASZ88_02122	COG1705	Flagellar rod assembly protein muramidase FlgJ
ASZ88_02123	COG1706	bacterial-type flagellum-dependent cell motility
ASZ88_02124	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ASZ88_02125	COG4786	Flagellar basal body rod
ASZ88_02126	COG4787	bacterial-type flagellum-dependent cell motility
ASZ88_02127	COG1749	Flagellar hook protein flgE
ASZ88_02128	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ASZ88_02129	COG1558	bacterial-type flagellum-dependent cell motility
ASZ88_02130	COG1815	bacterial-type flagellum-dependent cell motility
ASZ88_02131	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASZ88_02132	COG0835	chemotaxis
ASZ88_02132	COG0784	Response regulator, receiver
ASZ88_02139	COG2226	methyltransferase
ASZ88_02139	COG3433	isochorismatase activity
ASZ88_02139	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASZ88_02140	COG2375	cellular response to nickel ion
ASZ88_02141	COG1629	transport
ASZ88_02141	COG4774	siderophore transport
ASZ88_02144	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASZ88_02145	COG2608	mercury ion transmembrane transporter activity
ASZ88_02145	COG2217	Heavy metal translocating P-type atpase
ASZ88_02148	COG3735	TraB family
ASZ88_02151	COG2840	Smr protein MutS2
ASZ88_02152	COG1187	pseudouridine synthase activity
ASZ88_02153	COG3706	GGDEF domain
ASZ88_02155	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ASZ88_02156	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ASZ88_02157	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ASZ88_02158	COG0121	glutamine amidotransferase
ASZ88_02159	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ASZ88_02160	COG1960	acyl-CoA dehydrogenase activity
ASZ88_02162	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASZ88_02163	COG0328	RNA-DNA hybrid ribonuclease activity
ASZ88_02164	COG2226	methyltransferase
ASZ88_02165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASZ88_02166	COG0741	lytic transglycosylase activity
ASZ88_02166	COG1388	LysM domain
ASZ88_02168	COG0347	Belongs to the P(II) protein family
ASZ88_02169	COG3479	Phenolic acid decarboxylase
ASZ88_02171	COG0037	tRNA processing
ASZ88_02172	COG0825	malonyl-CoA metabolic process
ASZ88_02173	COG0587	DNA-directed DNA polymerase activity
ASZ88_02174	COG0587	DNA-directed DNA polymerase activity
ASZ88_02175	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ASZ88_02176	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASZ88_02177	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASZ88_02178	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASZ88_02179	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASZ88_02180	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ASZ88_02182	COG0750	zinc metalloprotease
ASZ88_02183	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ASZ88_02184	COG0575	Belongs to the CDS family
ASZ88_02185	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASZ88_02186	COG0233	cytoplasmic translational termination
ASZ88_02187	COG0528	UMP kinase activity
ASZ88_02188	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ASZ88_02189	COG0052	Belongs to the universal ribosomal protein uS2 family
ASZ88_02190	COG0024	Methionine aminopeptidase
ASZ88_02191	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ASZ88_02193	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ASZ88_02194	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ASZ88_02195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASZ88_02196	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ASZ88_02199	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASZ88_02199	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASZ88_02200	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASZ88_02201	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ASZ88_02202	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ASZ88_02205	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ASZ88_02206	COG2252	PERMEase
ASZ88_02207	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASZ88_02208	COG0189	ligase activity
ASZ88_02208	COG4067	protein conserved in archaea
ASZ88_02209	COG0189	ligase activity
ASZ88_02211	COG0733	neurotransmitter:sodium symporter activity
ASZ88_02212	COG3706	GGDEF domain
ASZ88_02214	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASZ88_02216	COG1477	protein flavinylation
ASZ88_02217	COG2871	sodium ion transport
ASZ88_02218	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASZ88_02219	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASZ88_02220	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASZ88_02221	COG1805	sodium ion transport
ASZ88_02222	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASZ88_02223	COG0271	Belongs to the BolA IbaG family
ASZ88_02224	COG2813	Specifically methylates the guanine in position
ASZ88_02226	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ASZ88_02227	COG2211	Major facilitator Superfamily
ASZ88_02229	COG1595	DNA-templated transcription, initiation
ASZ88_02231	COG3248	Nucleoside-binding outer membrane protein
ASZ88_02232	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ASZ88_02233	COG0693	protein deglycase activity
ASZ88_02234	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASZ88_02235	COG2166	iron-sulfur cluster assembly
ASZ88_02236	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ASZ88_02237	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ASZ88_02239	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASZ88_02239	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ASZ88_02241	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ASZ88_02242	COG1074	ATP-dependent DNA helicase activity
ASZ88_02243	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ASZ88_02246	COG3141	response to X-ray
ASZ88_02247	COG2171	N-acyltransferase activity
ASZ88_02249	COG0456	acetyltransferase
ASZ88_02251	COG0189	ligase activity
ASZ88_02251	COG0569	domain protein
ASZ88_02254	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASZ88_02255	COG1609	Transcriptional regulator
ASZ88_02256	COG3250	beta-galactosidase activity
ASZ88_02259	COG1022	Amp-dependent synthetase and ligase
ASZ88_02260	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASZ88_02261	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ASZ88_02263	COG0560	Phosphoserine phosphatase
ASZ88_02265	COG0813	purine-nucleoside phosphorylase activity
ASZ88_02266	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ASZ88_02267	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ASZ88_02268	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ASZ88_02269	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASZ88_02270	COG0084	hydrolase, TatD family'
ASZ88_02273	COG1115	amino acid carrier protein
ASZ88_02276	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ASZ88_02277	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ASZ88_02278	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
ASZ88_02279	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ASZ88_02280	COG0083	homoserine kinase activity
ASZ88_02283	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ASZ88_02285	COG0745	RESPONSE REGULATOR receiver
ASZ88_02286	COG2198	Histidine kinase
ASZ88_02286	COG0784	Response regulator, receiver
ASZ88_02286	COG5002	protein histidine kinase activity
ASZ88_02287	COG2203	Gaf domain
ASZ88_02287	COG3706	GGDEF domain
ASZ88_02287	COG4251	negative regulation of phosphorylation
ASZ88_02287	COG5001	Diguanylate cyclase
ASZ88_02288	COG1242	4 iron, 4 sulfur cluster binding
ASZ88_02289	COG0067	glutamate synthase
ASZ88_02289	COG0070	glutamate synthase
ASZ88_02289	COG0069	glutamate synthase activity
ASZ88_02291	COG0070	glutamate synthase
ASZ88_02291	COG0069	glutamate synthase activity
ASZ88_02291	COG0067	glutamate synthase
ASZ88_02292	COG0493	'glutamate synthase
ASZ88_02294	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ASZ88_02296	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASZ88_02297	COG2860	membrane
ASZ88_02298	COG0583	DNA-binding transcription factor activity
ASZ88_02299	COG0730	response to heat
ASZ88_02301	COG4172	Belongs to the ABC transporter superfamily
ASZ88_02305	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ASZ88_02306	COG0505	Belongs to the CarA family
ASZ88_02307	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ASZ88_02308	COG0494	nUDIX hydrolase
ASZ88_02309	COG0653	protein targeting
ASZ88_02311	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ASZ88_02312	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ASZ88_02313	COG0849	cell division
ASZ88_02314	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ASZ88_02315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASZ88_02316	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ASZ88_02317	COG0772	Belongs to the SEDS family
ASZ88_02318	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ASZ88_02319	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASZ88_02320	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASZ88_02321	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ASZ88_02322	COG0768	penicillin binding
ASZ88_02323	COG3116	cell division
ASZ88_02324	COG0275	rRNA processing
ASZ88_02325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASZ88_02326	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASZ88_02327	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ASZ88_02328	COG2186	Transcriptional regulator
ASZ88_02329	COG0737	Belongs to the 5'-nucleotidase family
ASZ88_02330	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASZ88_02331	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASZ88_02332	COG4974	Belongs to the 'phage' integrase family
ASZ88_02333	COG0716	FMN binding
ASZ88_02337	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASZ88_02338	COG1459	type II secretion system
ASZ88_02340	COG0237	dephospho-CoA kinase activity
ASZ88_02341	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ASZ88_02342	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ASZ88_02343	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ASZ88_02344	COG0187	DNA topoisomerase II activity
ASZ88_02345	COG3150	esterase
ASZ88_02347	COG3151	Protein conserved in bacteria
ASZ88_02348	COG0494	nUDIX hydrolase
ASZ88_02349	COG1538	Outer membrane efflux protein
ASZ88_02351	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ASZ88_02352	COG0840	transmembrane signaling receptor activity
ASZ88_02354	COG3025	triphosphatase activity
ASZ88_02355	COG1392	Phosphate transport regulator
ASZ88_02356	COG0306	phosphate transporter
ASZ88_02357	COG4991	sh3 domain protein
ASZ88_02359	COG3267	Type II secretory pathway component ExeA
ASZ88_02359	COG3409	Peptidoglycan-binding domain 1 protein
ASZ88_02360	COG0617	tRNA 3'-terminal CCA addition
ASZ88_02361	COG0148	phosphopyruvate hydratase activity
ASZ88_02362	COG0504	CTP synthase activity
ASZ88_02363	COG3956	TIGRFAM MazG family protein
ASZ88_02364	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASZ88_02365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASZ88_02367	COG5001	Diguanylate cyclase
ASZ88_02370	COG0736	holo-[acyl-carrier-protein] synthase activity
ASZ88_02371	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ASZ88_02372	COG1381	Involved in DNA repair and RecF pathway recombination
ASZ88_02373	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ASZ88_02374	COG0571	ribonuclease III activity
ASZ88_02375	COG0681	Belongs to the peptidase S26 family
ASZ88_02376	COG0481	GTPase activity
ASZ88_02377	COG3086	response to oxidative stress
ASZ88_02378	COG3026	antisigma factor binding
ASZ88_02380	COG1595	DNA-templated transcription, initiation
ASZ88_02381	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ASZ88_02383	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ASZ88_02384	COG0354	folic acid binding
ASZ88_02386	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASZ88_02387	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASZ88_02389	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ASZ88_02390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ASZ88_02391	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ASZ88_02392	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASZ88_02393	COG0440	acetolactate synthase activity
ASZ88_02394	COG0028	Belongs to the TPP enzyme family
ASZ88_02395	COG1022	Amp-dependent synthetase and ligase
ASZ88_02396	COG0583	DNA-binding transcription factor activity
ASZ88_02400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASZ88_02401	COG0473	3-isopropylmalate dehydrogenase activity
ASZ88_02402	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ASZ88_02403	COG0066	3-isopropylmalate dehydratase activity
ASZ88_02412	COG3437	response regulator, receiver
ASZ88_02415	COG0795	lipopolysaccharide-transporting ATPase activity
ASZ88_02416	COG0795	lipopolysaccharide-transporting ATPase activity
ASZ88_02417	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASZ88_02418	COG2927	DNA polymerase III (CHI subunit)
ASZ88_02419	COG0525	valine-tRNA ligase activity
ASZ88_02420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASZ88_02421	COG0564	pseudouridine synthase activity
ASZ88_02422	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASZ88_02423	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ASZ88_02424	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ASZ88_02425	COG0540	Belongs to the ATCase OTCase family
ASZ88_02426	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
ASZ88_02427	COG0251	oxidation-reduction process
ASZ88_02428	COG0204	Acyl-transferase
ASZ88_02429	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ASZ88_02430	COG5007	Belongs to the BolA IbaG family
ASZ88_02432	COG2854	intermembrane phospholipid transfer
ASZ88_02433	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ASZ88_02434	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASZ88_02435	COG1127	ABC transporter
ASZ88_02437	COG0517	IMP dehydrogenase activity
ASZ88_02437	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ASZ88_02440	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ASZ88_02441	COG1137	ATPase activity
ASZ88_02443	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ASZ88_02444	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ88_02446	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ88_02447	COG2239	Acts as a magnesium transporter
ASZ88_02448	COG0312	modulator of DNA gyrase
ASZ88_02449	COG3028	Belongs to the UPF0307 family
ASZ88_02450	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ASZ88_02451	COG1178	ABC-type Fe3 transport system permease component
ASZ88_02452	COG4143	(ABC) transporter
ASZ88_02453	COG0163	prenyltransferase activity
ASZ88_02454	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASZ88_02455	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ASZ88_02456	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ASZ88_02457	COG2105	PFAM AIG2 family protein
ASZ88_02459	COG0729	surface antigen
ASZ88_02460	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ88_02461	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ASZ88_02464	COG1136	(ABC) transporter
ASZ88_02468	COG0529	Catalyzes the synthesis of activated sulfate
ASZ88_02469	COG2895	sulfate adenylyltransferase (ATP) activity
ASZ88_02470	COG0175	sulfate reduction
ASZ88_02471	COG1648	precorrin-2 dehydrogenase activity
ASZ88_02471	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ASZ88_02472	COG0737	Belongs to the 5'-nucleotidase family
ASZ88_02474	COG0513	Belongs to the DEAD box helicase family
ASZ88_02475	COG2153	protein acetylation
ASZ88_02476	COG0697	spore germination
ASZ88_02477	COG3266	domain, Protein
ASZ88_02477	COG3061	Opacity-associated protein A
ASZ88_02478	COG0545	Peptidyl-prolyl cis-trans isomerase
ASZ88_02480	COG0203	ribosomal protein L17
ASZ88_02481	COG0202	RNA polymerase activity
ASZ88_02482	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ASZ88_02483	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ASZ88_02484	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ASZ88_02486	COG0201	protein transport
ASZ88_02487	COG0200	Binds to the 23S rRNA
ASZ88_02488	COG1841	ribosomal large subunit assembly
ASZ88_02489	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ASZ88_02490	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ASZ88_02491	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ASZ88_02492	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ASZ88_02493	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASZ88_02494	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ASZ88_02495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ASZ88_02496	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ASZ88_02497	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ASZ88_02498	COG0255	Belongs to the universal ribosomal protein uL29 family
ASZ88_02499	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ASZ88_02500	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASZ88_02501	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ASZ88_02502	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ASZ88_02503	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ASZ88_02504	COG0089	rRNA binding
ASZ88_02505	COG0088	Forms part of the polypeptide exit tunnel
ASZ88_02506	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASZ88_02507	COG0051	transcription antitermination factor activity, RNA binding
ASZ88_02508	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASZ88_02509	COG0557	exoribonuclease II activity
ASZ88_02510	COG3083	sulfuric ester hydrolase activity
ASZ88_02511	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ASZ88_02512	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ASZ88_02514	COG1047	Peptidyl-prolyl cis-trans
ASZ88_02517	COG2249	NAD(P)H dehydrogenase (quinone) activity
ASZ88_02518	COG0488	(ABC) transporter
ASZ88_02520	COG0429	hydrolase of the alpha beta-hydrolase fold
ASZ88_02522	COG3954	Phosphoribulokinase
ASZ88_02523	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASZ88_02525	COG1012	belongs to the aldehyde dehydrogenase family
ASZ88_02527	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASZ88_02529	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASZ88_02532	COG0180	Tryptophanyl-tRNA synthetase
ASZ88_02533	COG0546	phosphoglycolate phosphatase activity
ASZ88_02534	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASZ88_02535	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ASZ88_02537	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ASZ88_02538	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ASZ88_02544	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ASZ88_02546	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASZ88_02546	COG0678	peroxiredoxin activity
ASZ88_02547	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASZ88_02549	COG0165	Argininosuccinate lyase
ASZ88_02550	COG0137	argininosuccinate synthase activity
ASZ88_02551	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASZ88_02552	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASZ88_02553	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASZ88_02554	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ASZ88_02556	COG1045	serine acetyltransferase
ASZ88_02557	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ASZ88_02558	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ASZ88_02559	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASZ88_02560	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ASZ88_02561	COG1053	succinate dehydrogenase
ASZ88_02562	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ASZ88_02563	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ASZ88_02564	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ASZ88_02565	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASZ88_02566	COG1509	lysine 2,3-aminomutase activity
ASZ88_02568	COG0459	protein refolding
ASZ88_02569	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ASZ88_02574	COG0149	triose-phosphate isomerase activity
ASZ88_02576	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ASZ88_02577	COG1575	Belongs to the MenA family. Type 1 subfamily
ASZ88_02578	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ASZ88_02579	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ASZ88_02580	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ASZ88_02581	COG1609	Transcriptional regulator
ASZ88_02582	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ASZ88_02583	COG0254	rRNA binding
ASZ88_02584	COG0281	malic enzyme
ASZ88_02585	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
ASZ88_02586	COG0626	cystathionine gamma-synthase activity
ASZ88_02587	COG0527	aspartate kinase activity
ASZ88_02587	COG0460	homoserine dehydrogenase
ASZ88_02588	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ASZ88_02589	COG3074	FtsZ-dependent cytokinesis
ASZ88_02590	COG1494	fructose-1,6-bisphosphatase
ASZ88_02591	COG0205	6-phosphofructokinase activity
ASZ88_02592	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ASZ88_02594	COG0745	RESPONSE REGULATOR receiver
ASZ88_02595	COG2205	protein histidine kinase activity
ASZ88_02597	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ASZ88_02598	COG3030	protein affecting phage T7 exclusion by the F plasmid
ASZ88_02599	COG3706	GGDEF domain
ASZ88_02600	COG1027	Aspartate ammonia-lyase
ASZ88_02601	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ASZ88_02604	COG4232	protein-disulfide reductase activity
ASZ88_02606	COG3263	regulation of cellular component size
ASZ88_02608	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASZ88_02609	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ASZ88_02610	COG0194	GDP metabolic process
ASZ88_02611	COG1758	RNA polymerase activity
ASZ88_02612	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASZ88_02613	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASZ88_02614	COG2233	PERMEase
ASZ88_02616	COG0745	RESPONSE REGULATOR receiver
ASZ88_02617	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASZ88_02618	COG2183	response to ionizing radiation
ASZ88_02620	COG0596	Alpha beta hydrolase
ASZ88_02621	COG1040	competence protein
ASZ88_02622	COG0316	Belongs to the HesB IscA family
ASZ88_02622	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ASZ88_02623	COG0494	nUDIX hydrolase
ASZ88_02624	COG1218	3'(2'),5'-bisphosphate nucleotidase
ASZ88_02626	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ASZ88_02627	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ASZ88_02628	COG3156	type II secretion system protein K
ASZ88_02629	COG4795	General secretion pathway protein
ASZ88_02630	COG2165	general secretion pathway protein
ASZ88_02631	COG2165	general secretion pathway protein
ASZ88_02632	COG2165	general secretion pathway protein
ASZ88_02633	COG1459	type II secretion system
ASZ88_02634	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASZ88_02636	COG3031	protein transport across the cell outer membrane
ASZ88_02637	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ASZ88_02638	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ASZ88_02639	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ASZ88_02641	COG0456	acetyltransferase
ASZ88_02642	COG1490	D-aminoacyl-tRNA deacylase activity
ASZ88_02647	COG0174	glutamine synthetase
ASZ88_02649	COG3852	Histidine kinase
ASZ88_02651	COG3300	MHYT domain
ASZ88_02651	COG5001	Diguanylate cyclase
ASZ88_02652	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ASZ88_02666	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ASZ88_02667	COG1404	Belongs to the peptidase S8 family
ASZ88_02668	COG4206	TonB-dependent receptor
ASZ88_02672	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ASZ88_02673	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ASZ88_02674	COG4181	ATPase activity
ASZ88_02676	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASZ88_02677	COG1716	ATPase activity
ASZ88_02677	COG5001	Diguanylate cyclase
ASZ88_02679	COG0484	heat shock protein binding
ASZ88_02688	COG0546	phosphoglycolate phosphatase activity
ASZ88_02691	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASZ88_02692	COG1368	sulfuric ester hydrolase activity
ASZ88_02694	COG0513	Belongs to the DEAD box helicase family
ASZ88_02695	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
ASZ88_02697	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASZ88_02699	COG3046	protein related to deoxyribodipyrimidine photolyase
ASZ88_02700	COG3397	chitin binding
ASZ88_02701	COG3227	Zinc metalloprotease (Elastase)
ASZ88_02703	COG0010	Belongs to the arginase family
ASZ88_02704	COG1166	arginine decarboxylase activity
ASZ88_02706	COG2239	Acts as a magnesium transporter
ASZ88_02707	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ASZ88_02708	COG0459	protein refolding
ASZ88_02710	COG0527	aspartate kinase activity
ASZ88_02711	COG0662	Cupin 2, conserved barrel domain protein
ASZ88_02712	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ASZ88_02713	COG0456	acetyltransferase
ASZ88_02714	COG2154	pterin-4-alpha-carbinolamine dehydratase
ASZ88_02715	COG3186	Phenylalanine-4-hydroxylase
ASZ88_02716	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASZ88_02719	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASZ88_02720	COG0583	DNA-binding transcription factor activity
ASZ88_02723	COG2171	N-acyltransferase activity
ASZ88_02724	COG1253	flavin adenine dinucleotide binding
ASZ88_02725	COG1765	OsmC-like protein
ASZ88_02730	COG0531	amino acid
ASZ88_02731	COG3706	GGDEF domain
ASZ88_02733	COG3279	Response regulator of the LytR AlgR family
ASZ88_02734	COG3275	phosphorelay sensor kinase activity
ASZ88_02737	COG0577	efflux transmembrane transporter activity
ASZ88_02737	COG1136	(ABC) transporter
ASZ88_02738	COG1136	(ABC) transporter
ASZ88_02740	COG4989	oxidoreductase activity
ASZ88_02741	COG0366	Alpha amylase catalytic
ASZ88_02742	COG2067	long-chain fatty acid transport protein
ASZ88_02743	COG2267	carboxylic ester hydrolase activity
ASZ88_02745	COG3227	Zinc metalloprotease (Elastase)
ASZ88_02746	COG3047	cAMP biosynthetic process
ASZ88_02748	COG1686	Belongs to the peptidase S11 family
ASZ88_02749	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASZ88_02750	COG1271	oxidase subunit
ASZ88_02751	COG1294	oxidase, subunit
ASZ88_02754	COG3048	D-serine ammonia-lyase activity
ASZ88_02755	COG0583	DNA-binding transcription factor activity
ASZ88_02762	COG1063	alcohol dehydrogenase
ASZ88_02765	COG0693	protein deglycase activity
ASZ88_02768	COG0346	lactoylglutathione lyase activity
ASZ88_02773	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ASZ88_02774	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ASZ88_02775	COG0363	glucosamine-6-phosphate deaminase activity
ASZ88_02776	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ASZ88_02781	COG1929	Belongs to the glycerate kinase type-1 family
ASZ88_02782	COG2610	gluconate transmembrane transporter activity
ASZ88_02783	COG3835	regulator
ASZ88_02785	COG0748	coenzyme F420 binding
ASZ88_02786	COG3721	Heme iron utilization protein
ASZ88_02788	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ASZ88_02789	COG0811	peptide transport
ASZ88_02790	COG0848	biopolymer transport protein
ASZ88_02791	COG4558	Periplasmic binding protein
ASZ88_02792	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASZ88_02793	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ASZ88_02800	COG0633	Ferredoxin
ASZ88_02800	COG3217	Mosc domain protein beta barrel domain protein
ASZ88_02800	COG3217	Mosc domain protein beta barrel domain protein
ASZ88_02800	COG0633	Ferredoxin
ASZ88_02801	COG0418	dihydroorotase activity
ASZ88_02803	COG3152	Membrane
ASZ88_02805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASZ88_02806	COG2354	Protein conserved in bacteria
ASZ88_02807	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ASZ88_02808	COG1278	Cold shock
ASZ88_02813	COG3706	GGDEF domain
ASZ88_02814	COG1349	DNA-binding transcription factor activity
ASZ88_02817	COG3833	ABC-type maltose transport systems, permease component
ASZ88_02818	COG1175	transmembrane transport
ASZ88_02820	COG3842	ATPase activity
ASZ88_02821	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ88_02824	COG0393	Putative heavy-metal-binding
ASZ88_02825	COG2197	response regulator
ASZ88_02826	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASZ88_02827	COG0784	Response regulator, receiver
ASZ88_02827	COG0835	chemotaxis
ASZ88_02828	COG1846	Transcriptional regulator
ASZ88_02829	COG3706	GGDEF domain
ASZ88_02836	COG0583	DNA-binding transcription factor activity
ASZ88_02837	COG5001	Diguanylate cyclase
ASZ88_02839	COG1741	Belongs to the pirin family
ASZ88_02840	COG3123	guanosine phosphorylase activity
ASZ88_02842	COG2211	Major facilitator Superfamily
ASZ88_02844	COG0840	transmembrane signaling receptor activity
ASZ88_02845	COG1067	ATP-dependent peptidase activity
ASZ88_02847	COG4172	Belongs to the ABC transporter superfamily
ASZ88_02851	COG0583	DNA-binding transcription factor activity
ASZ88_02852	COG1620	l-lactate permease
ASZ88_02853	COG1304	FMN binding
ASZ88_02855	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ASZ88_02857	COG0840	transmembrane signaling receptor activity
ASZ88_02859	COG0513	Belongs to the DEAD box helicase family
ASZ88_02860	COG0583	DNA-binding transcription factor activity
ASZ88_02862	COG1902	pentaerythritol trinitrate reductase activity
ASZ88_02864	COG1132	(ABC) transporter
ASZ88_02866	COG1902	pentaerythritol trinitrate reductase activity
ASZ88_02868	COG1280	lysine exporter protein (LysE YggA)
ASZ88_02869	COG2207	Transcriptional regulator
ASZ88_02873	COG1846	Transcriptional regulator
ASZ88_02874	COG1764	response to oxidative stress
ASZ88_02875	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASZ88_02876	COG0697	spore germination
ASZ88_02878	COG0700	Nucleoside recognition
ASZ88_02879	COG3366	ferrous iron transmembrane transporter activity
ASZ88_02880	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ASZ88_02882	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASZ88_02883	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ASZ88_02884	COG2259	Doxx family
ASZ88_02889	COG0363	glucosamine-6-phosphate deaminase activity
ASZ88_02892	COG4580	involved in the transport of maltose and maltodextrins
ASZ88_02895	COG0840	transmembrane signaling receptor activity
ASZ88_02898	COG0840	transmembrane signaling receptor activity
ASZ88_02900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASZ88_02901	COG1126	abc transporter atp-binding protein
ASZ88_02903	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASZ88_02904	COG4597	amino acid ABC transporter
ASZ88_02905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASZ88_02906	COG0739	heme binding
ASZ88_02908	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ88_02908	COG2213	PTS system mannitol-specific
ASZ88_02909	COG0246	Mannitol dehydrogenase
ASZ88_02910	COG3722	fumarate hydratase activity
ASZ88_02911	COG0673	inositol 2-dehydrogenase activity
ASZ88_02917	COG2910	NAD(P)H-binding
ASZ88_02919	COG0840	transmembrane signaling receptor activity
ASZ88_02920	COG4221	oxidoreductase activity
ASZ88_02922	COG1901	pseudouridine methyltransferase
ASZ88_02923	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASZ88_02924	COG0531	amino acid
ASZ88_02925	COG1982	Orn Lys Arg decarboxylase major
ASZ88_02930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASZ88_02935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ASZ88_02937	COG0259	pyridoxamine-phosphate oxidase activity
ASZ88_02943	COG0745	RESPONSE REGULATOR receiver
ASZ88_02947	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ASZ88_02948	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASZ88_02949	COG0840	transmembrane signaling receptor activity
ASZ88_02950	COG0835	chemotaxis
ASZ88_02951	COG0835	chemotaxis
ASZ88_02952	COG2198	Histidine kinase
ASZ88_02952	COG0643	Histidine kinase
ASZ88_02956	COG0601	transmembrane transport
ASZ88_02957	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASZ88_02959	COG2194	sulfuric ester hydrolase activity
ASZ88_02960	COG0642	Histidine kinase
ASZ88_02961	COG0745	RESPONSE REGULATOR receiver
ASZ88_02967	COG1444	tRNA N-acetyltransferase activity
ASZ88_02968	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASZ88_02975	COG0217	transcriptional regulatory protein
ASZ88_02976	COG2084	Dehydrogenase
ASZ88_02979	COG2909	trisaccharide binding
ASZ88_02980	COG0058	SHG alpha-glucan phosphorylase activity
ASZ88_02981	COG1640	4-alpha-glucanotransferase
ASZ88_02982	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ASZ88_02984	COG3501	Rhs element vgr protein
ASZ88_02991	COG0471	metal ion transport
ASZ88_02992	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ASZ88_03000	COG0671	phosphoesterase, PA-phosphatase related
ASZ88_03001	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ASZ88_03003	COG1999	signal sequence binding
ASZ88_03006	COG0786	glutamate:sodium symporter activity
ASZ88_03010	COG1566	PFAM secretion protein HlyD family protein
ASZ88_03012	COG3706	GGDEF domain
ASZ88_03015	COG0813	purine-nucleoside phosphorylase activity
ASZ88_03016	COG3272	Protein of unknown function (DUF1722)
ASZ88_03018	COG0415	Belongs to the DNA photolyase family
ASZ88_03019	COG1388	LysM domain
ASZ88_03019	COG1376	ErfK ybiS ycfS ynhG family protein
ASZ88_03021	COG0513	Belongs to the DEAD box helicase family
ASZ88_03022	COG1770	oligopeptidase
ASZ88_03028	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASZ88_03029	COG0573	inorganic phosphate transmembrane transporter activity
ASZ88_03030	COG0581	inorganic phosphate transmembrane transporter activity
ASZ88_03031	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASZ88_03035	COG0659	secondary active sulfate transmembrane transporter activity
ASZ88_03037	COG0739	heme binding
ASZ88_03038	COG5001	Diguanylate cyclase
ASZ88_03038	COG3300	MHYT domain
ASZ88_03040	COG0583	DNA-binding transcription factor activity
ASZ88_03041	COG2814	Major facilitator Superfamily
ASZ88_03046	COG1301	dicarboxylic acid transport
ASZ88_03048	COG1342	Belongs to the UPF0251 family
ASZ88_03054	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ASZ88_03055	COG0673	inositol 2-dehydrogenase activity
ASZ88_03057	COG2200	EAL domain
ASZ88_03057	COG2771	luxR family
ASZ88_03058	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASZ88_03060	COG0564	pseudouridine synthase activity
ASZ88_03078	COG3501	Rhs element vgr protein
ASZ88_03081	COG1869	D-ribose catabolic process
ASZ88_03082	COG1129	ABC transporter
ASZ88_03083	COG1172	Belongs to the binding-protein-dependent transport system permease family
ASZ88_03084	COG1879	ABC-type sugar transport system periplasmic component
ASZ88_03085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASZ88_03086	COG1609	Transcriptional regulator
ASZ88_03089	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ASZ88_03091	COG0584	glycerophosphoryl diester phosphodiesterase
ASZ88_03092	COG2271	Major facilitator Superfamily
ASZ88_03099	COG0579	oxidoreductase
ASZ88_03101	COG0242	peptide deformylase activity
ASZ88_03103	COG1320	monovalent cation:proton antiporter activity
ASZ88_03104	COG2212	antiporter activity
ASZ88_03108	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASZ88_03108	COG2111	Na H antiporter
ASZ88_03110	COG0589	response to stress
ASZ88_03111	COG0814	amino acid
ASZ88_03112	COG3033	Beta-eliminating lyase
ASZ88_03114	COG3530	Putative quorum-sensing-regulated virulence factor
ASZ88_03116	COG5002	protein histidine kinase activity
ASZ88_03116	COG5001	Diguanylate cyclase
ASZ88_03117	COG1278	Cold shock
ASZ88_03120	COG2304	oxidoreductase activity
ASZ88_03124	COG0714	Associated with various cellular activities
ASZ88_03125	COG0840	transmembrane signaling receptor activity
ASZ88_03128	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASZ88_03129	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASZ88_03131	COG3604	Transcriptional regulator
ASZ88_03132	COG1017	nitric oxide dioxygenase activity
ASZ88_03132	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASZ88_03133	COG1278	Cold shock
ASZ88_03134	COG3036	rescue of stalled ribosome
ASZ88_03139	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ASZ88_03139	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ASZ88_03140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASZ88_03142	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASZ88_03144	COG0516	GMP reductase activity
ASZ88_03145	COG4974	Belongs to the 'phage' integrase family
ASZ88_03167	COG4695	Portal protein
ASZ88_03191	COG0516	GMP reductase activity
ASZ88_03196	COG1943	Transposase
ASZ88_03197	COG0513	Belongs to the DEAD box helicase family
ASZ88_03198	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ASZ88_03199	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ASZ88_03200	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ASZ88_03202	COG0784	Response regulator, receiver
ASZ88_03202	COG3437	response regulator, receiver
ASZ88_03203	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASZ88_03203	COG4191	Histidine kinase
ASZ88_03205	COG1757	Na H antiporter
ASZ88_03206	COG2814	Major facilitator Superfamily
ASZ88_03207	COG3706	GGDEF domain
ASZ88_03208	COG3240	lipase activity
ASZ88_03210	COG0840	transmembrane signaling receptor activity
ASZ88_03211	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ASZ88_03212	COG5380	lipid catabolic process
ASZ88_03213	COG4412	M6 family metalloprotease domain protein
ASZ88_03213	COG3291	Pkd domain containing protein
ASZ88_03217	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASZ88_03218	COG4605	iron ion homeostasis
ASZ88_03219	COG4604	ABC transporter, ATP-binding protein
ASZ88_03223	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASZ88_03227	COG0745	RESPONSE REGULATOR receiver
ASZ88_03229	COG3623	hexulose-6-phosphate isomerase
ASZ88_03230	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ASZ88_03231	COG0561	phosphatase activity
ASZ88_03237	COG3038	cytochrome b561
ASZ88_03238	COG0366	Alpha amylase catalytic
ASZ88_03243	COG0745	RESPONSE REGULATOR receiver
ASZ88_03244	COG5002	protein histidine kinase activity
ASZ88_03249	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASZ88_03252	COG2814	Major facilitator Superfamily
ASZ88_03255	COG1686	Belongs to the peptidase S11 family
ASZ88_03260	COG1943	Transposase
ASZ88_03261	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASZ88_03261	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASZ88_03262	COG0509	glycine decarboxylation via glycine cleavage system
ASZ88_03263	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASZ88_03265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ASZ88_03267	COG3039	Transposase
ASZ88_03272	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ASZ88_03274	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ASZ88_03275	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ASZ88_03299	COG1418	mRNA catabolic process
ASZ88_03311	COG1028	Short-chain dehydrogenase reductase Sdr
ASZ88_03314	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ASZ88_03319	COG0494	nUDIX hydrolase
ASZ88_03321	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ88_03322	COG3040	lipid binding
ASZ88_03326	COG3041	Addiction module toxin RelE StbE family
ASZ88_03331	COG1619	proteins homologs of microcin C7 resistance protein MccF
ASZ88_03332	COG3549	Plasmid maintenance system killer
ASZ88_03333	COG3093	addiction module antidote protein HigA
ASZ88_03354	COG1619	proteins homologs of microcin C7 resistance protein MccF
ASZ88_03360	COG3040	lipid binding
ASZ88_03367	COG3549	Plasmid maintenance system killer
ASZ88_03368	COG3093	addiction module antidote protein HigA
ASZ88_03369	COG0384	phenazine biosynthesis protein PhzF
ASZ88_03375	COG0346	lactoylglutathione lyase activity
ASZ88_03378	COG3040	lipid binding
ASZ88_03401	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ88_03417	COG1619	proteins homologs of microcin C7 resistance protein MccF
ASZ88_03421	COG3040	lipid binding
ASZ88_03431	COG1943	Transposase
ASZ88_03433	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ASZ88_03434	COG4977	sequence-specific DNA binding
ASZ88_03447	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ASZ88_03448	COG2944	sequence-specific DNA binding
ASZ88_03451	COG3039	Transposase
ASZ88_03452	COG0110	maltose O-acetyltransferase activity
ASZ88_03455	COG0346	lactoylglutathione lyase activity
ASZ88_03471	COG1943	Transposase
ASZ88_03481	COG0346	lactoylglutathione lyase activity
ASZ88_03486	COG1328	CTP reductase activity
ASZ88_03487	COG0602	queuosine metabolic process
ASZ88_03489	COG0189	ligase activity
ASZ88_03489	COG4067	protein conserved in archaea
ASZ88_03490	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ASZ88_03490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ88_03490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ88_03491	COG1105	Belongs to the carbohydrate kinase PfkB family
ASZ88_03492	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ88_03492	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ88_03493	COG1609	Transcriptional regulator
ASZ88_03494	COG0420	3'-5' exonuclease activity
ASZ88_03495	COG0419	ATPase involved in DNA repair
ASZ88_03496	COG0784	Response regulator, receiver
ASZ88_03496	COG2205	protein histidine kinase activity
ASZ88_03497	COG0156	8-amino-7-oxononanoate synthase activity
ASZ88_03499	COG0038	chloride channel
ASZ88_03500	COG0523	cobalamin synthesis protein
ASZ88_03502	COG3158	transport of potassium into the cell
ASZ88_03503	COG0674	pyruvate-flavodoxin oxidoreductase activity
ASZ88_03503	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ASZ88_03503	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASZ88_03503	COG1013	pyruvate-flavodoxin oxidoreductase activity
ASZ88_03504	COG2205	protein histidine kinase activity
ASZ88_03505	COG0745	RESPONSE REGULATOR receiver
ASZ88_03506	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASZ88_03507	COG0586	Pfam SNARE associated Golgi protein
ASZ88_03509	COG2200	EAL domain
ASZ88_03511	COG3038	cytochrome b561
ASZ88_03513	COG2116	formate transmembrane transporter activity
ASZ88_03514	COG0583	DNA-binding transcription factor activity
ASZ88_03516	COG3593	DNA synthesis involved in DNA repair
ASZ88_03517	COG0737	Belongs to the 5'-nucleotidase family
ASZ88_03521	COG2824	Alkylphosphonate utilization operon protein PhnA
ASZ88_03531	COG3706	GGDEF domain
ASZ88_03534	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ASZ88_03535	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ASZ88_03537	COG0745	RESPONSE REGULATOR receiver
ASZ88_03548	COG4128	Pfam Zonular occludens toxin
ASZ88_03558	COG4128	Pfam Zonular occludens toxin
ASZ88_03561	COG0023	Translation Initiation Factor
ASZ88_03563	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASZ88_03565	COG0045	succinate-CoA ligase (ADP-forming) activity
ASZ88_03565	COG1042	CoA-binding domain protein
ASZ88_03565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ88_03566	COG0583	DNA-binding transcription factor activity
ASZ88_03567	COG1629	transport
ASZ88_03567	COG4771	TonB-dependent receptor
ASZ88_03570	COG2050	protein possibly involved in aromatic compounds catabolism
ASZ88_03574	COG0625	glutathione transferase activity
ASZ88_03577	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASZ88_03578	COG4172	Belongs to the ABC transporter superfamily
ASZ88_03579	COG4239	(ABC) transporter, permease
ASZ88_03580	COG4174	ABC transporter (Permease)
ASZ88_03581	COG4166	transmembrane transport
ASZ88_03590	COG3842	ATPase activity
ASZ88_03592	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ASZ88_03594	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASZ88_03595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASZ88_03596	COG1011	Hydrolase
ASZ88_03598	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ASZ88_03599	COG1970	mechanosensitive ion channel activity
ASZ88_03600	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ASZ88_03601	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ88_03601	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ88_03602	COG0302	gtp cyclohydrolase
ASZ88_03604	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ASZ88_03606	COG2897	thiosulfate sulfurtransferase activity
ASZ88_03607	COG2390	Transcriptional regulator
ASZ88_03608	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASZ88_03609	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASZ88_03615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASZ88_03620	COG0583	DNA-binding transcription factor activity
ASZ88_03621	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ASZ88_03622	COG0778	Nitroreductase
ASZ88_03627	COG0640	Transcriptional regulator
ASZ88_03629	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASZ88_03638	COG1263	PTS System
ASZ88_03638	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ88_03640	COG1621	beta-fructofuranosidase activity
ASZ88_03641	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASZ88_03642	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ASZ88_03644	COG2885	chlorophyll binding
ASZ88_03645	COG0545	Peptidyl-prolyl cis-trans isomerase
ASZ88_03646	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASZ88_03647	COG0840	transmembrane signaling receptor activity
ASZ88_03648	COG3069	C4-dicarboxylate transmembrane transporter activity
ASZ88_03649	COG1760	l-serine dehydratase
ASZ88_03653	COG1609	Transcriptional regulator
ASZ88_03654	COG2197	response regulator
ASZ88_03655	COG3850	Histidine kinase
ASZ88_03656	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASZ88_03658	COG0243	molybdopterin cofactor binding
ASZ88_03662	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ASZ88_03663	COG2197	response regulator
ASZ88_03664	COG3851	Histidine kinase
ASZ88_03665	COG2271	Major facilitator Superfamily
ASZ88_03666	COG1840	ABC-type Fe3 transport system, periplasmic component
ASZ88_03668	COG3842	ATPase activity
ASZ88_03669	COG3243	poly(R)-hydroxyalkanoic acid synthase
ASZ88_03671	COG0183	Belongs to the thiolase family
ASZ88_03673	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASZ88_03674	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASZ88_03677	COG3706	GGDEF domain
ASZ88_03678	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ASZ88_03680	COG1979	alcohol dehydrogenase
ASZ88_03683	COG4191	Histidine kinase
ASZ88_03684	COG1840	ABC-type Fe3 transport system, periplasmic component
ASZ88_03686	COG2271	Major facilitator Superfamily
ASZ88_03687	COG0469	pyruvate kinase activity
ASZ88_03688	COG2198	Histidine kinase
ASZ88_03688	COG2205	protein histidine kinase activity
ASZ88_03688	COG0784	Response regulator, receiver
ASZ88_03689	COG1879	ABC-type sugar transport system periplasmic component
ASZ88_03690	COG1803	Methylglyoxal synthase
ASZ88_03691	COG1335	isochorismatase
ASZ88_03692	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ASZ88_03695	COG0210	DNA helicase
ASZ88_03696	COG1289	transmembrane transporter activity
ASZ88_03702	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ASZ88_03703	COG4149	molybdate abc transporter
ASZ88_03704	COG0725	ABC transporter, periplasmic molybdate-binding protein
ASZ88_03705	COG1492	cobalamin metabolic process
ASZ88_03713	COG0784	Response regulator, receiver
ASZ88_03713	COG5002	protein histidine kinase activity
ASZ88_03714	COG1879	ABC-type sugar transport system periplasmic component
ASZ88_03716	COG2827	Endonuclease containing a URI domain
ASZ88_03723	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ASZ88_03724	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ASZ88_03725	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
ASZ88_03726	COG0247	lactate metabolic process
ASZ88_03727	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASZ88_03728	COG3118	belongs to the thioredoxin family
ASZ88_03734	COG0583	DNA-binding transcription factor activity
ASZ88_03735	COG4160	amino acid transport
ASZ88_03736	COG4215	(ABC) transporter
ASZ88_03737	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASZ88_03738	COG1126	abc transporter atp-binding protein
ASZ88_03740	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ASZ88_03742	COG0494	nUDIX hydrolase
ASZ88_03743	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ASZ88_03745	COG1309	transcriptional regulator
ASZ88_03746	COG0513	Belongs to the DEAD box helicase family
ASZ88_03747	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
ASZ88_03749	COG0814	amino acid
ASZ88_03750	COG0840	transmembrane signaling receptor activity
ASZ88_03751	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ASZ88_03752	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ASZ88_03754	COG1984	allophanate hydrolase subunit 2
ASZ88_03757	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ASZ88_03758	COG4181	ATPase activity
ASZ88_03760	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASZ88_03761	COG3300	MHYT domain
ASZ88_03761	COG5001	Diguanylate cyclase