locus-tag	class	description
AP033_10001	ENOG4105CXY	transporter
AP033_10002	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AP033_10004	ENOG4108I5U	Uridine phosphorylase
AP033_10005	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
AP033_10006	ENOG4105ETE	Transcriptional regulator (LacI family
AP033_10007	ENOG4108RVA	ribokinase
AP033_10008	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AP033_10009	ENOG4105CNN	ABC, transporter
AP033_10010	ENOG4105C2J	ABC transporter
AP033_10011	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
AP033_10014	ENOG4105CS6	Rhs element vgr protein
AP033_10020	ENOG4108JUB	Transcriptional regulator
AP033_10021	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AP033_10033	ENOG4105D3G	Pseudouridine synthase
AP033_10035	ENOG4107VXZ	Hydrolase
AP033_10036	ENOG4105BZU	Histidine kinase
AP033_10037	ENOG4107YZP	Rhodanese domain protein
AP033_10038	ENOG4105D9R	oxidoreductase
AP033_10039	ENOG4107RH7	Nicotinate phosphoribosyltransferase
AP033_10048	ENOG4105CK2	sodium dicarboxylate symporter
AP033_10052	ENOG4108Z4X	TRANSCRIPTIONal
AP033_10053	ENOG4105E5M	Multidrug resistance protein D
AP033_10054	ENOG4105EQ2	LysR family Transcriptional regulator
AP033_10055	ENOG4105BZU	Histidine kinase
AP033_10056	ENOG4105DR5	peptidase
AP033_10058	ENOG4105CHH	sulfate transporter
AP033_10059	ENOG4105DWD	nucleoside recognition domain protein
AP033_10061	ENOG4105BZU	Histidine kinase
AP033_10062	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AP033_10063	ENOG4105E2Z	phosphate ABC transporter (Permease
AP033_10064	ENOG4105C8U	phosphate abc transporter
AP033_10065	ENOG4105CVA	phosphate
AP033_10071	ENOG4105CUG	Oligopeptidase b
AP033_10072	ENOG4105C1J	atp-dependent rna helicase
AP033_10074	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
AP033_10075	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AP033_10077	ENOG4107SEY	Conserved Protein
AP033_10078	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
AP033_10081	ENOG4106TD9	Diguanylate cyclase
AP033_10082	ENOG4105KK7	inner membrane protein YiaW
AP033_10083	ENOG4105EFX	secretion protein, HlyD family
AP033_10086	ENOG4105YE1	PilZ domain
AP033_10087	ENOG4105D6U	Sodium Glutamate Symporter
AP033_10092	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
AP033_10093	ENOG4105EYK	Phosphatidylglycerophosphatase B
AP033_10097	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_10101	ENOG4108Q67	UPF0319 protein
AP033_10102	ENOG4105C8P	)-transporter
AP033_10104	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AP033_10109	ENOG4105CS6	Rhs element vgr protein
AP033_10110	ENOG4108WC9	type VI secretion system effector, hcp1 family
AP033_10111	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AP033_10112	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
AP033_10113	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
AP033_10114	ENOG41061ZR	Transcriptional regulator
AP033_10115	ENOG4108YYI	Protein of unknown function (DUF2810)
AP033_10116	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_10117	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AP033_10118	ENOG4105CDY	transcriptional regulatory protein
AP033_10124	ENOG4106RMF	ParB family
AP033_10125	ENOG4107RUE	extracellular solute-binding protein family 1
AP033_10126	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
AP033_10132	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AP033_10133	ENOG4105DHQ	Histidine kinase
AP033_10134	ENOG4105DIJ	Phosphoethanolamine transferase
AP033_10136	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AP033_10137	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AP033_10140	ENOG4108VYJ	response regulator receiver protein
AP033_10141	ENOG4105CBS	Chea signal transduction histidine kinase
AP033_10142	ENOG4108V3W	Chemotaxis protein, CheW
AP033_10143	ENOG4108V3W	Chemotaxis protein, CheW
AP033_10144	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_10145	ENOG4105BZU	Histidine kinase
AP033_10146	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AP033_10147	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AP033_10148	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_10150	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AP033_10152	ENOG4108JJA	ABC, transporter
AP033_10155	ENOG4107QZV	Type I secretion membrane fusion protein
AP033_10156	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AP033_10159	ENOG4105E6M	Sulphatase-modifying factor protein
AP033_10162	ENOG4105C26	Dehydrogenase
AP033_10164	ENOG4105CK7	Sodium proline symporter
AP033_10166	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_10167	ENOG4105EW9	transcriptional regulator AsnC family
AP033_10168	ENOG4107RGH	Aldehyde dehydrogenase
AP033_10169	ENOG4105CXN	decarboxylase
AP033_10170	ENOG4105D5Q	Arginine ornithine antiporter
AP033_10171	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AP033_10173	ENOG4105JQN	Transcriptional regulator
AP033_10174	ENOG4105EMU	Dehydrogenase
AP033_10175	ENOG41069D7	Methyl-accepting chemotaxis
AP033_10176	ENOG4105JQN	Transcriptional regulator
AP033_10177	ENOG4108RYK	Nad-dependent epimerase dehydratase
AP033_10179	ENOG4108W2Y	isochorismatase
AP033_10182	ENOG4108KTG	Membrane protein, drug metabolite transporter
AP033_10187	ENOG4105EP9	oxidoreductase
AP033_10188	ENOG4105E61	Mannitol repressor protein
AP033_10189	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
AP033_10190	ENOG4105CTS	PTS system mannitol-specific
AP033_10192	ENOG4105DR5	peptidase
AP033_10193	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
AP033_10194	ENOG4105EZ7	amino acid ABC transporter
AP033_10195	ENOG4106TNF	Periplasmic binding protein
AP033_10197	ENOG4105CDA	abc transporter atp-binding protein
AP033_10198	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AP033_10200	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_10203	ENOG4108N3W	hemolysin secretion protein
AP033_10206	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
AP033_10207	ENOG4107W52	maltose operon periplasmic protein
AP033_10210	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AP033_10215	ENOG4108VGI	doxx family
AP033_10216	ENOG4105D03	DNA-3-methyladenine glycosylase II
AP033_10217	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AP033_10219	ENOG4105DN9	Na H antiporter
AP033_10220	ENOG41074DU	domain protein
AP033_10221	ENOG4108P2H	Inner membrane protein YjiG
AP033_10222	ENOG4105VW4	glutaredoxin 3
AP033_10223	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AP033_10225	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AP033_10226	ENOG4105K56	Transcriptional regulator
AP033_10233	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AP033_10235	ENOG4105BZ1	(ABC) transporter
AP033_10237	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AP033_10239	ENOG4105CR8	Transcriptional regulator
AP033_10240	ENOG4105C1J	atp-dependent rna helicase
AP033_10242	ENOG4108NVR	Methyl-accepting chemotaxis
AP033_10243	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AP033_10245	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AP033_10247	ENOG4105DMF	Dehydrogenase
AP033_10248	ENOG4105DAA	L-lactate
AP033_10249	ENOG4105CC0	LysR family Transcriptional regulator
AP033_10251	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_10252	ENOG4105E89	ABC transporter
AP033_10253	ENOG4108JQ5	ABC transporter
AP033_10255	ENOG4105DAN	ATP-dependent protease
AP033_10256	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_10258	ENOG4105E5W	Transporter
AP033_10260	ENOG4105NBK	UPF0345 protein
AP033_10261	ENOG4105EUB	pirin domain protein
AP033_10263	ENOG4108K0B	C-di-gmp phosphodiesterase
AP033_10264	ENOG4105ETT	transcriptional Regulator, LysR family
AP033_10268	ENOG4105BZU	Histidine kinase
AP033_10271	ENOG4106TD9	Diguanylate cyclase
AP033_10272	ENOG4105K56	Transcriptional regulator
AP033_10273	ENOG4107R88	Chemotaxis protein (CheV)
AP033_10274	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
AP033_10275	ENOG41086KC	Transcriptional regulator
AP033_10276	ENOG4105K8R	UPF0145 protein
AP033_10279	ENOG4108HK0	-acetyltransferase
AP033_10280	ENOG4108IJ9	(ABC) transporter
AP033_10281	ENOG4107FKK	extracellular solute-binding protein family 1
AP033_10282	ENOG4105D56	permease protein
AP033_10283	ENOG4105EG2	ABC transporter, permease
AP033_10286	ENOG4105E98	transcriptional regulator DeoR family
AP033_10287	ENOG4105BZU	Histidine kinase
AP033_10292	ENOG4105VEQ	Cold shock protein
AP033_10293	ENOG4108ESY	Metal dependent phosphohydrolase
AP033_10294	ENOG4105CKW	Inner membrane protein yedI
AP033_10295	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
AP033_10297	ENOG4105KAF	membrAne
AP033_10299	ENOG4105EKE	dihydroorotase
AP033_10300	ENOG4105QVC	MOSC domain-containing protein
AP033_10300	ENOG4105QVC	MOSC domain-containing protein
AP033_10301	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_10307	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AP033_10308	ENOG4105EHG	Permease protein
AP033_10309	ENOG4107R4I	Periplasmic binding protein
AP033_10310	ENOG4106GFD	transport protein
AP033_10311	ENOG41090AP	transport protein
AP033_10312	ENOG4105WQ5	TonB family
AP033_10313	ENOG4105D4P	Coproporphyrinogen iii oxidase
AP033_10314	ENOG41090JE	Utilization Protein
AP033_10315	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
AP033_10316	ENOG4108NVR	Methyl-accepting chemotaxis
AP033_10317	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
AP033_10318	ENOG4105C6Z	Gluconate
AP033_10319	ENOG4105BZW	Glycerate kinase
AP033_10324	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AP033_10325	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
AP033_10326	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AP033_10327	ENOG4105DHT	Metal Dependent Phosphohydrolase
AP033_10328	ENOG4107SSZ	Phosphatase
AP033_10332	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
AP033_10333	ENOG4105EXG	Transcriptional regulator
AP033_10334	ENOG4108IQK	o-acetylhomoserine
AP033_10335	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AP033_10336	ENOG4105CPQ	Dehydrogenase
AP033_10337	ENOG4107RRE	RNA-directed DNA polymerase
AP033_10342	ENOG4107R08	Integrase
AP033_10349	ENOG4105CAR	Terminase, large subunit
AP033_10354	ENOG4105VEQ	Cold shock protein
AP033_10356	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AP033_10359	ENOG41082YX	Transcriptional regulator, arsr family
AP033_10360	ENOG4105D6J	arsenicaL-resistance protein
AP033_10383	ENOG4105C6Z	Gluconate
AP033_10384	ENOG4105EXW	epimerase dehydratase
AP033_10385	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
AP033_10386	ENOG4105FB2	class II Aldolase
AP033_10387	ENOG4105G63	Type III effector Hrp-dependent
AP033_10388	ENOG4105ZXK	Dehydrogenase
AP033_10389	ENOG4105MVE	transcriptional regulator
AP033_10391	ENOG4105F2I	Transposase
AP033_10392	ENOG4105BZC	d-serine deaminase
AP033_10395	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AP033_10396	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AP033_10397	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AP033_10398	ENOG41061WM	D-Alanyl-D-Alanine
AP033_10401	ENOG4105EIF	outer membrane protein W
AP033_10402	ENOG4105D4Y	metalloprotease
AP033_10403	ENOG4107SDU	Methyl-accepting chemotaxis
AP033_10404	ENOG4108M0H	Extracellular lipase
AP033_10405	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AP033_10406	ENOG4107T9C	Alpha amylase catalytic region
AP033_10407	ENOG4107RGM	aldo keto reductase
AP033_10409	ENOG4105C19	ABC transporter
AP033_10410	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AP033_10413	ENOG4108HRK	Histidine kinase
AP033_10414	ENOG4108VAC	response regulator
AP033_10417	ENOG4106TD9	Diguanylate cyclase
AP033_10418	ENOG4105DVH	amino acid
AP033_10422	ENOG4107YWA	deoxycytidylate deaminase
AP033_10423	ENOG4108UKZ	OsmC family
AP033_10424	ENOG4105C37	(CBS) domain
AP033_10425	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
AP033_10428	ENOG4105EGI	Transcriptional regulator
AP033_10429	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AP033_10432	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AP033_10433	ENOG4105MIR	Phenylalanine 4-monooxygenase
AP033_10434	ENOG41090A4	Pterin carbinolamine dehydratase
AP033_10435	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
AP033_10436	ENOG4108JPW	Aminotransferase
AP033_10437	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
AP033_10438	ENOG4105CZK	Aspartate kinase
AP033_10440	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AP033_10441	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AP033_10442	ENOG4105CJW	magnesium transporter
AP033_10444	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AP033_10445	ENOG4105CYW	agmatinase
AP033_10447	ENOG4105D4Y	metalloprotease
AP033_10448	ENOG4108M1A	Chitin-binding protein
AP033_10449	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
AP033_10451	ENOG4105CVA	phosphate
AP033_10453	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
AP033_10454	ENOG4105C1J	atp-dependent rna helicase
AP033_10456	ENOG4105E0M	Sulfatase
AP033_10457	ENOG4107RE1	Inosine-guanosine kinase
AP033_10460	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AP033_10470	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
AP033_10471	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
AP033_10472	ENOG4105CGF	Aromatic amino acid aminotransferase
AP033_10473	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AP033_10474	ENOG4105DM4	PTS System
AP033_10475	ENOG4105DE4	1-phosphofructokinase
AP033_10476	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
AP033_10477	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
AP033_10478	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
AP033_10479	ENOG4107RFY	SbcCD D subunit
AP033_10480	ENOG4105EYH	Exonuclease
AP033_10481	ENOG4108MGY	Histidine kinase
AP033_10482	ENOG4107KBT	8-Amino-7-oxononanoate synthase
AP033_10484	ENOG4105CMQ	Chloride channel
AP033_10485	ENOG4105CKI	cobalamin synthesis protein
AP033_10486	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AP033_10487	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AP033_10488	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AP033_10489	ENOG4105C08	Histidine kinase
AP033_10490	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
AP033_10492	ENOG4108RHM	integral membrane protein
AP033_10494	ENOG4105EPM	Diguanylate phosphodiesterase
AP033_10496	ENOG4105DS1	cytochrome b561
AP033_10498	ENOG4105TMB	Formate nitrite transporter
AP033_10499	ENOG4105DUM	transcriptional regulator, lysR family
AP033_10500	ENOG4108UQ5	membrane protein YcdZ
AP033_10501	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
AP033_10502	ENOG4105CGH	5'-nucleotidase
AP033_10504	ENOG4105DU1	integral membrane protein, terc
AP033_10506	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AP033_10512	ENOG4105BZU	Histidine kinase
AP033_10514	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AP033_10516	ENOG4105BZU	Histidine kinase
AP033_10519	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AP033_10520	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AP033_10522	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AP033_10527	ENOG4108ZJT	translation initiation factor, Sui1
AP033_10529	ENOG4105CPF	Cell wall formation (By similarity)
AP033_10531	ENOG4105CD5	CoA-binding domain protein
AP033_10532	ENOG4105CWB	LysR family transcriptional Regulator
AP033_10538	ENOG4105KA0	thioesterase Superfamily protein
AP033_10542	ENOG4105CYM	Glutathione S-transferase
AP033_10545	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AP033_10546	ENOG4108JQ5	ABC transporter
AP033_10547	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
AP033_10548	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
AP033_10549	ENOG4105E43	Extracellular solute-binding protein, family 5
AP033_10554	ENOG4105DUX	Transporter
AP033_10557	ENOG4107RCV	ABC transporter, permease
AP033_10560	ENOG4107STF	Involved in phosphonate degradation (By similarity)
AP033_10561	ENOG4108JPW	Aminotransferase
AP033_10562	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
AP033_10563	ENOG4105NXH	GreA GreB family elongation factor
AP033_10564	ENOG4105PAD	Hydrolase
AP033_10566	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
AP033_10567	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AP033_10568	ENOG4105CKU	formyltetrahydrofolate synthetase
AP033_10569	ENOG4105E0X	reductase
AP033_10570	ENOG4105EUJ	GTP cyclohydrolase i
AP033_10571	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AP033_10572	ENOG4105D06	uba thif-type nad fad binding protein
AP033_10574	ENOG4105KHC	sulfurtransferase
AP033_10576	ENOG4107RHR	regulatoR
AP033_10577	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AP033_10578	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AP033_10584	ENOG4108M3J	Dehydrogenase
AP033_10587	ENOG4105RA2	Membrane
AP033_10589	ENOG4105ETT	transcriptional Regulator, LysR family
AP033_10590	ENOG41067V3	Antibiotic biosynthesis monooxygenase
AP033_10591	ENOG4108RCM	Nitroreductase
AP033_10596	ENOG41080HT	Transcriptional regulator, arsr family
AP033_10598	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AP033_10607	ENOG4105C5Y	PTS System
AP033_10608	ENOG4105ETE	Transcriptional regulator (LacI family
AP033_10609	ENOG4107R3K	hydrolase
AP033_10610	ENOG4105D7K	pfkb domain protein
AP033_10611	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AP033_10612	ENOG4108NVR	Methyl-accepting chemotaxis
AP033_10613	ENOG4108ZG0	Ompa motb domain protein
AP033_10614	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AP033_10615	ENOG4107VXZ	Hydrolase
AP033_10616	ENOG4108N3W	hemolysin secretion protein
AP033_10617	ENOG4105CEE	C4-dicarboxylate transporter
AP033_10618	ENOG4105EJQ	L-serine dehydratase
AP033_10623	ENOG4105ETE	Transcriptional regulator (LacI family
AP033_10624	ENOG4105WH1	Two component transcriptional regulator luxr family
AP033_10625	ENOG4105BZU	Histidine kinase
AP033_10628	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AP033_10632	ENOG4105DHT	Metal Dependent Phosphohydrolase
AP033_10633	ENOG4108KX4	response regulator
AP033_10634	ENOG4105BZU	Histidine kinase
AP033_10635	ENOG4105CXY	transporter
AP033_10636	ENOG4105C4Y	ABC transporter
AP033_10637	ENOG4107RCV	ABC transporter, permease
AP033_10638	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AP033_10639	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AP033_10641	ENOG4105CHU	acetyl-coa acetyltransferase
AP033_10643	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AP033_10644	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AP033_10647	ENOG4105BZU	Histidine kinase
AP033_10648	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AP033_10650	ENOG4108I6A	alcohol dehydrogenase
AP033_10652	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
AP033_10654	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
AP033_10656	ENOG4105CXY	transporter
AP033_10657	ENOG4105CA9	Pyruvate kinase
AP033_10658	ENOG4105BZU	Histidine kinase
AP033_10659	ENOG4108SV3	Tmao reductase system periplasmic protein tort
AP033_10660	ENOG4108Z5K	methylglyoxal synthase
AP033_10661	ENOG4108RWI	nicotinamidase
AP033_10662	ENOG41080IJ	Diacylglycerol kinase
AP033_10665	ENOG41088T4	Helicase IV
AP033_10666	ENOG4105EM2	membrane
AP033_10672	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AP033_10673	ENOG4105E0C	molybdate abc transporter
AP033_10674	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AP033_10675	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AP033_10676	ENOG4105F2I	Transposase
AP033_10677	ENOG4105F2I	Transposase
AP033_10683	ENOG4105BZU	Histidine kinase
AP033_10684	ENOG4108QGH	periplasmic
AP033_10686	ENOG41082IR	Excinuclease ABC C subunit domain protein
AP033_10693	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AP033_10694	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
AP033_10695	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
AP033_10696	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AP033_10697	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AP033_10698	ENOG4105K63	Thioredoxin
AP033_10703	ENOG4105DMR	ABC, transporter
AP033_10704	ENOG4105GBT	ABC transporter
AP033_10705	ENOG4106PMH	Extracellular solute-binding protein family 3
AP033_10706	ENOG4105E5Z	arginine transporter ATP-binding subunit
AP033_10708	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
AP033_10710	ENOG4108YZ4	nudix hydrolase
AP033_10711	ENOG4105C5W	Aldolase
AP033_10712	ENOG4106RE7	Cytochrome
AP033_10713	ENOG4108IG5	Transcriptional regulator
AP033_10714	ENOG4105C1J	atp-dependent rna helicase
AP033_10715	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
AP033_10717	ENOG4105E0U	tyrosine-specific transport protein
AP033_10718	ENOG4108N3W	hemolysin secretion protein
AP033_10719	ENOG4105CMR	udp-glucose 4-epimerase
AP033_10720	ENOG4105E7W	lamb ycsf family protein
AP033_10722	ENOG4107R7A	Allophanate hydrolase subunit 2
AP033_10724	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AP033_10725	ENOG4105CV6	ABC transporter, permease
AP033_10726	ENOG4108I0Y	(ABC) transporter
AP033_10728	ENOG4105RKW	reductase (By
AP033_10731	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AP033_10737	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AP033_10747	ENOG4108RS6	transposase
AP033_10759	ENOG4105F2I	Transposase
AP033_10766	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AP033_10769	ENOG4105EQK	-acetyltransferase
AP033_10770	ENOG4105F2I	Transposase
AP033_10776	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AP033_10786	ENOG4105QNF	Outer membrane lipoprotein
AP033_10806	ENOG4105F2I	Transposase
AP033_10808	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AP033_10814	ENOG4108S58	Phenazine biosynthesis protein PhzF
AP033_10815	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
AP033_10816	ENOG41080ET	plasmid maintenance system killer protein
AP033_10831	ENOG4105F2I	Transposase
AP033_10841	ENOG4105F2I	Transposase
AP033_10842	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
AP033_10845	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
AP033_10855	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AP033_10864	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AP033_10877	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
AP033_10890	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AP033_10891	ENOG41082NX	50s ribosomal protein l35
AP033_10892	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AP033_10893	ENOG4105C22	threonyL-tRNA synthetase
AP033_10922	ENOG4105KUS	lysozyme
AP033_10932	ENOG4108XTP	Transcriptional regulator
AP033_10941	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AP033_10943	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AP033_10944	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AP033_10945	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AP033_10946	ENOG4108RS6	transposase
AP033_10951	ENOG4105DZ1	carboxypeptidase
AP033_10953	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_10954	ENOG4105C2C	drug resistance transporter, Bcr CflA
AP033_10957	ENOG4107QVI	Methyltransferase, type 11
AP033_10962	ENOG4105BZU	Histidine kinase
AP033_10963	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AP033_10968	ENOG4105DS1	cytochrome b561
AP033_10974	ENOG410667J	hydrolase
AP033_10976	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
AP033_10978	ENOG4105ETX	regulatoR
AP033_10982	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AP033_10986	ENOG4108IPW	abc transporter atp-binding protein
AP033_10987	ENOG4105CM4	permease protein
AP033_10988	ENOG4105DHS	permease protein
AP033_10992	ENOG4107G87	m6 family metalloprotease domain protein
AP033_10994	ENOG4107IFA	Lipase (EC 3.1.1.3)
AP033_10995	ENOG4108N3W	hemolysin secretion protein
AP033_10996	ENOG4106M3D	hemolysin
AP033_10997	ENOG4105KUU	lipolytic protein G-D-S-L family
AP033_10998	ENOG4105BZU	Histidine kinase
AP033_10999	ENOG4105E5M	Multidrug resistance protein D
AP033_11000	ENOG4107S6Z	Na H antiporter
AP033_11002	ENOG4105BZU	Histidine kinase
AP033_11003	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AP033_11004	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AP033_11005	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
AP033_11006	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
AP033_11007	ENOG4105C1J	atp-dependent rna helicase
AP033_11009	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AP033_11013	ENOG4105C5I	Dehydrogenase
AP033_11014	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AP033_11016	ENOG4108UNF	response regulator
AP033_11020	ENOG4105VEQ	Cold shock protein
AP033_11021	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AP033_11022	ENOG4108JUA	Transcriptional regulator
AP033_11024	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AP033_11025	ENOG4105D9N	nucleoside
AP033_11028	ENOG41069D7	Methyl-accepting chemotaxis
AP033_11029	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AP033_11036	ENOG4105VEQ	Cold shock protein
AP033_11037	ENOG4105BZU	Histidine kinase
AP033_11039	ENOG4105VRT	cytoplasmic protein
AP033_11040	ENOG4105C0F	tryptophanase EC 4.1.99.1
AP033_11041	ENOG4105CIC	tryptophan-specific transport protein
AP033_11042	ENOG4105Q9Y	Universal stress protein
AP033_11044	ENOG4105D65	subunit l
AP033_11045	ENOG4105MKQ	Monovalent cation H antiporter subunit C
AP033_11046	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AP033_11047	ENOG4105SC1	monovalent cation H antiporter subunit E
AP033_11048	ENOG41080TA	Multiple resistance and ph regulation protein f
AP033_11049	ENOG4105KJM	monovalent cation h antiporter subunit g
AP033_11050	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AP033_11051	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AP033_11053	ENOG4105D5U	fad dependent oxidoreductase
AP033_11056	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AP033_11057	ENOG4105CQZ	Histidine kinase
AP033_20001	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
AP033_20002	ENOG4105CEN	a g-specific adenine glycosylase
AP033_20003	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AP033_20004	ENOG4105CSV	Glutaminase
AP033_20005	ENOG4105CSA	Coproporphyrinogen iii oxidase
AP033_20006	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AP033_20008	ENOG4105VZ9	UPF0235 protein
AP033_20009	ENOG4108VIA	integral membrane protein
AP033_20010	ENOG4105II7	pyrroline-5-carboxylate reductase
AP033_20011	ENOG4105DFA	alanine racemase domain protein
AP033_20012	ENOG4105CZX	twitching motility protein
AP033_20013	ENOG4105CZX	twitching motility protein
AP033_20015	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AP033_20016	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AP033_20017	ENOG4108UJU	UPF0301 protein
AP033_20018	ENOG4105D7Z	glutathione synthase
AP033_20019	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AP033_20020	ENOG4105RWS	endonuclease I
AP033_20021	ENOG4105GPY	SprT protein
AP033_20022	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AP033_20023	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AP033_20024	ENOG4108R4R	Iron-regulated virulence regulatory protein
AP033_20025	ENOG4105D05	Receptor
AP033_20026	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AP033_20027	ENOG4105BZA	Phosphoglycerate kinase
AP033_20028	ENOG4105D2N	Aldolase
AP033_20029	ENOG4105D64	Mechanosensitive ion channel
AP033_20030	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
AP033_20031	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
AP033_20032	ENOG4105MPN	Membrane
AP033_20034	ENOG4105CA9	Pyruvate kinase
AP033_20035	ENOG410804X	Transcriptional regulator
AP033_20036	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AP033_20037	ENOG4105CH5	extracellular solute-binding protein, family 7
AP033_20040	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AP033_20041	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AP033_20042	ENOG4105KTH	gatB Yqey
AP033_20043	ENOG4105VCC	30S ribosomal protein S21
AP033_20044	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AP033_20046	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AP033_20047	ENOG4107ZVW	dihydroneopterin aldolase
AP033_20048	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AP033_20049	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AP033_20051	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AP033_20052	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AP033_20053	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AP033_20054	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AP033_20055	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AP033_20056	ENOG4108K5P	(LipO)protein
AP033_20057	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AP033_20058	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AP033_20059	ENOG4105C6T	cysteine synthase
AP033_20060	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
AP033_20061	ENOG4108I5D	sulfate abc transporter
AP033_20062	ENOG4105ECW	sulfate abc transporter
AP033_20063	ENOG4108IJ6	ABC transporter
AP033_20065	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AP033_20066	ENOG4105Y3E	Modulates RecA activity (By similarity)
AP033_20067	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AP033_20068	ENOG4105CFH	Aspartokinase
AP033_20069	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AP033_20079	ENOG4107QSA	Oxaloacetate decarboxylase
AP033_20080	ENOG4105D9Q	decarboxylase (Beta subunit)
AP033_20082	ENOG4105W39	Membrane
AP033_20084	ENOG4105D9M	gamma-glutamylcysteine synthetase
AP033_20085	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AP033_20086	ENOG4108JU6	CBS domain protein
AP033_20087	ENOG4106KVJ	cytochrome C assembly protein
AP033_20089	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AP033_20090	ENOG4105K5M	30s ribosomal protein S16
AP033_20091	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AP033_20092	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AP033_20093	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AP033_20094	ENOG4105C0H	protease
AP033_20095	ENOG4105C0H	protease
AP033_20097	ENOG4105D6Z	AFG1 family ATPase
AP033_20098	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AP033_20099	ENOG4108UJD	30S ribosomal protein S9
AP033_20100	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AP033_20101	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AP033_20102	ENOG4105EIX	cytochrome c1
AP033_20103	ENOG4107MKT	Stringent starvation protein a
AP033_20104	ENOG4105KB2	stringent starvation protein b
AP033_20105	ENOG4105W4M	Transport-associated protein
AP033_20106	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AP033_20107	ENOG41082RQ	UPF0102 protein
AP033_20108	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
AP033_20109	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AP033_20110	ENOG410630P	Transcriptional regulator
AP033_20111	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AP033_20112	ENOG41077A9	carbonic anhydrase
AP033_20113	ENOG4105CHH	sulfate transporter
AP033_20114	ENOG4105DA5	(ABC) transporter
AP033_20115	ENOG4105E3A	(ABC) transporter
AP033_20116	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AP033_20117	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AP033_20118	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AP033_20119	ENOG4105DJ0	Poly(A) Polymerase
AP033_20120	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AP033_20121	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AP033_20122	ENOG4105PW4	Sugar fermentation stimulation protein homolog
AP033_20124	ENOG4105CQ7	ATP-dependent helicase
AP033_20125	ENOG4105BZ4	penicillin-binding protein
AP033_20126	ENOG4105D78	K07001 NTE family protein
AP033_20127	ENOG4107QIJ	Aconitate hydratase 2
AP033_20128	ENOG4105XTV	UPF0231 protein
AP033_20129	ENOG4108YZA	Nitrogen regulatory protein pii
AP033_20133	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AP033_20135	ENOG4105E2V	Glycosyltransferase 36
AP033_20136	ENOG4105E2D	ec 3.2.1.52
AP033_20137	ENOG4105RD7	BadF BadG BcrA BcrD
AP033_20139	ENOG4108JQ7	(ABC) transporter
AP033_20140	ENOG4105C3U	ABC transporter
AP033_20141	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AP033_20143	ENOG4107QRA	Extracellular solute-binding protein, family 5
AP033_20144	ENOG4105BZU	Histidine kinase
AP033_20145	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AP033_20146	ENOG4105IPI	Membrane
AP033_20148	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AP033_20149	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AP033_20152	ENOG4105DR5	peptidase
AP033_20153	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AP033_20154	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
AP033_20155	ENOG4105FCK	Membrane
AP033_20156	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AP033_20157	ENOG4105HBR	Rna-binding protein
AP033_20158	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AP033_20159	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AP033_20160	ENOG4105EEI	dihydropteroate synthase
AP033_20161	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AP033_20166	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AP033_20167	ENOG4105CHV	Transcription elongation factor NusA
AP033_20168	ENOG4105CHV	Transcription elongation factor NusA
AP033_20169	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AP033_20170	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AP033_20171	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AP033_20172	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AP033_20173	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AP033_20174	ENOG4105RT1	May be involved in cell division (By similarity)
AP033_20177	ENOG4106RZ4	Peptidase U32
AP033_20178	ENOG4105CFP	Peptidase U32
AP033_20179	ENOG4105BZU	Histidine kinase
AP033_20180	ENOG4105XPQ	lipid carrier protein
AP033_20181	ENOG4108YYD	acetyltransferase
AP033_20184	ENOG4105BZU	Histidine kinase
AP033_20185	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AP033_20186	ENOG4105C1J	atp-dependent rna helicase
AP033_20187	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
AP033_20188	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
AP033_20189	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AP033_20190	ENOG4105CRK	lysyL-tRNA synthetase
AP033_20191	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AP033_20193	ENOG4105CPC	Aldo Keto reductase
AP033_20194	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
AP033_20195	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AP033_20196	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
AP033_20197	ENOG4105HF0	Membrane
AP033_20198	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AP033_20199	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AP033_20201	ENOG41063Z6	transcriptional regulator, lysR family
AP033_20202	ENOG41080HT	Transcriptional regulator, arsr family
AP033_20203	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AP033_20204	ENOG4105CJR	Integral membrane protein (MviN
AP033_20205	ENOG4105DTN	riboflavin biosynthesis protein ribF
AP033_20206	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AP033_20207	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AP033_20208	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AP033_20209	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AP033_20213	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AP033_20214	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AP033_20215	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AP033_20216	ENOG4108NEV	two component transcriptional regulator, LytTR family
AP033_20217	ENOG4108HRK	Histidine kinase
AP033_20218	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AP033_20221	ENOG4105C5H	ABC transporter
AP033_20222	ENOG4107SC1	transglycosylase
AP033_20223	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
AP033_20224	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AP033_20225	ENOG4108K0B	C-di-gmp phosphodiesterase
AP033_20226	ENOG4107XW0	Spermidine putrescine ABC transporter periplasmic spermidine putrescine-binding protein
AP033_20228	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
AP033_20229	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AP033_20230	ENOG4105C34	Pseudouridine synthase
AP033_20231	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AP033_20232	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AP033_20240	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AP033_20241	ENOG4105CFP	Peptidase U32
AP033_20242	ENOG4105DH7	May be involved in recombination (By similarity)
AP033_20243	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AP033_20244	ENOG4105BZU	Histidine kinase
AP033_20246	ENOG4105C9X	ppx gppa phosphatase
AP033_20247	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AP033_20248	ENOG4105C8U	phosphate abc transporter
AP033_20249	ENOG4105E2Z	phosphate ABC transporter (Permease
AP033_20250	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AP033_20252	ENOG4105CSR	polyphosphate kinase 2
AP033_20253	ENOG4106N3A	copper homeostasis protein cutc
AP033_20254	ENOG4105D3R	alkyl hydroperoxide reductase
AP033_20255	ENOG4105C5Q	Transcriptional regulator
AP033_20256	ENOG4107QP3	malate synthase g
AP033_20257	ENOG4108I9X	Isocitrate lyase
AP033_20258	ENOG4105W87	Cbs domain
AP033_20259	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AP033_20260	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AP033_20261	ENOG4105VIE	preprotein translocase, subunit YajC
AP033_20262	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AP033_20263	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AP033_20264	ENOG4105ECY	inositol monophosphatase
AP033_20265	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
AP033_20266	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
AP033_20267	ENOG4105C3J	Cysteine desulfurase
AP033_20268	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
AP033_20269	ENOG4108Z4V	iron-sulfur cluster assembly
AP033_20270	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
AP033_20272	ENOG4108ZIT	Ferredoxin, 2FE-2S
AP033_20273	ENOG4105WVQ	Fe-S assembly protein IscX
AP033_20274	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AP033_20275	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AP033_20278	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AP033_20279	ENOG4105CUT	histidyl-tRNA synthetase
AP033_20280	ENOG4105N21	Membrane
AP033_20281	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AP033_20282	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AP033_20285	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AP033_20286	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AP033_20287	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AP033_20289	ENOG4106HK8	GPR1 FUN34 yaaH family protein
AP033_20290	ENOG4105WQI	isochorismatase
AP033_20291	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
AP033_20292	ENOG4105E4F	Isochorismate synthase
AP033_20293	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
AP033_20295	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
AP033_20296	ENOG4105DQ5	transport system permease protein
AP033_20297	ENOG4105TVJ	transport system, permease
AP033_20298	ENOG4105E0A	ABC, transporter
AP033_20300	ENOG41064T2	transcriptional regulator, lysR family
AP033_20301	ENOG4105EUZ	Beta-lactamase domain protein
AP033_20302	ENOG4105BZG	amino acid carrier protein
AP033_20303	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AP033_20307	ENOG4106YYS	transcriptional regulatory protein
AP033_20308	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AP033_20309	ENOG4105D9Q	decarboxylase (Beta subunit)
AP033_20310	ENOG4107QSA	Oxaloacetate decarboxylase
AP033_20313	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
AP033_20314	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
AP033_20315	ENOG4105CI0	Citrate lyase
AP033_20316	ENOG4105CHY	citrate lyase, alpha
AP033_20317	ENOG4105YGP	holo-ACP synthase CitX
AP033_20318	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
AP033_20321	ENOG4108Z4U	Ferredoxin
AP033_20322	ENOG4105DZ0	fad dependent oxidoreductase
AP033_20331	ENOG4105F2I	Transposase
AP033_20343	ENOG4105C26	Dehydrogenase
AP033_20347	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
AP033_20348	ENOG4107RK6	Methyl-accepting chemotaxis
AP033_20351	ENOG4105XB6	Toxin coregulated pilin
AP033_20354	ENOG4105GRU	toxin co-regulated pilus biosynthesis outer membrane protein C
AP033_20358	ENOG4107QHF	type ii secretion system protein e
AP033_20359	ENOG4108VEY	type ii secretion system
AP033_20363	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AP033_20364	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_20368	ENOG4105DR5	peptidase
AP033_20370	ENOG4105F88	accessory colonization factor AcfD
AP033_20371	ENOG4105DFP	Integrase
AP033_20372	ENOG4105DFP	Integrase
AP033_20374	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AP033_20375	ENOG4108Z1B	Cyclase dehydrase
AP033_20376	ENOG4105VDB	UPF0125 protein
AP033_20377	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AP033_20378	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AP033_20379	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AP033_20380	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AP033_20381	ENOG4105CFG	Acts as a chaperone (By similarity)
AP033_20382	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AP033_20388	ENOG4105CFC	Transporter
AP033_20389	ENOG4108Z6B	deaminase
AP033_20391	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
AP033_20392	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AP033_20393	ENOG4108RS6	transposase
AP033_20397	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AP033_20398	ENOG4108R96	Methyltransferase, YaeB family
AP033_20399	ENOG4105NRA	50s ribosomal protein l31 type b
AP033_20401	ENOG4105CFC	Transporter
AP033_20402	ENOG4108UPT	UPF0178 protein
AP033_20404	ENOG4108428	Inherit from COG: -acetyltransferase
AP033_20407	ENOG4105WP7	tRNA pseudouridine synthase C
AP033_20408	ENOG4105DR9	pseudouridine synthase
AP033_20409	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AP033_20410	ENOG4105CTB	Polyprenyl synthetase
AP033_20412	ENOG4105E14	MotA TolQ exbB proton channel
AP033_20413	ENOG4106VK6	Flagellar motor protein
AP033_20414	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AP033_20415	ENOG4105ETT	transcriptional Regulator, LysR family
AP033_20416	ENOG4105M08	Membrane
AP033_20417	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
AP033_20418	ENOG4105EWT	decarboxylase family
AP033_20419	ENOG4105BZU	Histidine kinase
AP033_20421	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AP033_20422	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
AP033_20423	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
AP033_20424	ENOG4105D01	(LipO)protein
AP033_20425	ENOG4108UMI	ABC transporter, permease
AP033_20426	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AP033_20427	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
AP033_20428	ENOG4105D4X	repressor
AP033_20429	ENOG4105C5Y	PTS System
AP033_20430	ENOG4105CG3	alpha amylase, catalytic region
AP033_20436	ENOG4105BZS	acriflavin resistance protein
AP033_20437	ENOG4105KJF	protein tyrosine phosphatase
AP033_20438	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AP033_20440	ENOG4108UW5	maltose o-acetyltransferase
AP033_20444	ENOG4105D7W	serine acetyltransferase
AP033_20446	ENOG4105Q84	sucrose synthase
AP033_20448	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
AP033_20451	ENOG4108MA4	Peptidase M66
AP033_20454	ENOG4105D3Q	Sugar transferase
AP033_20456	ENOG4105DAY	polysaccharide export protein
AP033_20457	ENOG4105D75	Capsular exopolysaccharide family
AP033_20461	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AP033_20463	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AP033_20464	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AP033_20465	ENOG4108Z43	UPF0250 protein
AP033_20466	ENOG4105DZ1	carboxypeptidase
AP033_20467	ENOG4105K6T	rare lipoprotein A
AP033_20468	ENOG4105CNI	cell division protein FtsW
AP033_20469	ENOG4105CJN	penicillin-binding protein
AP033_20470	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AP033_20471	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
AP033_20472	ENOG4105DJF	DNA polymerase III, delta' subunit
AP033_20473	ENOG4108U2H	Rare lipoprotein B
AP033_20474	ENOG4105C8T	Leucyl-tRNA synthetase
AP033_20475	ENOG4107PAI	alpha helical protein
AP033_20476	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AP033_20477	ENOG4108JU5	Magnesium and cobalt efflux protein
AP033_20478	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AP033_20479	ENOG4105C9A	Phoh family
AP033_20480	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AP033_20481	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AP033_20482	ENOG4105C5Y	PTS System
AP033_20484	ENOG4105KZ7	phosphocarrier protein hpr
AP033_20485	ENOG4105C6T	cysteine synthase
AP033_20486	ENOG4105EXN	Sulfate transport protein CysZ
AP033_20487	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
AP033_20488	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AP033_20489	ENOG41081QG	Porin Gram-negative type
AP033_20491	ENOG4108Z6Z	Transcriptional regulator
AP033_20492	ENOG4105G5H	Membrane
AP033_20493	ENOG4107QX8	SPFH domain, Band 7 family protein
AP033_20494	ENOG4107QR8	Thioredoxin
AP033_20495	ENOG4105F2I	Transposase
AP033_20496	ENOG4105E1F	short-chain dehydrogenase reductase
AP033_20497	ENOG4105ECP	epimerase
AP033_20498	ENOG4108RE9	Phosphodiesterase
AP033_20501	ENOG4108TU9	TRANSCRIPTIONal
AP033_20502	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AP033_20503	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AP033_20504	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AP033_20505	ENOG4105DUX	Transporter
AP033_20506	ENOG4105MDZ	Transcriptional activator rfaH
AP033_20507	ENOG4105CAQ	asparagine synthetase
AP033_20508	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AP033_20509	ENOG4105E2R	ROK family
AP033_20510	ENOG4105CE4	GlcNAc 6-P deacetylase
AP033_20511	ENOG4105CI1	PTS System
AP033_20512	ENOG4105CX6	glutaminyL-tRNA synthetase
AP033_20514	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AP033_20515	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AP033_20516	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AP033_20517	ENOG4108S3P	Sporulation domain protein
AP033_20518	ENOG4105E96	Colicin v production protein
AP033_20519	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AP033_20520	ENOG4105D3Y	Na H antiporter
AP033_20521	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AP033_20522	ENOG4105EIY	sodium-type flagellar protein motY
AP033_20523	ENOG4106WH9	Protein of unknown function (DUF2753)
AP033_20524	ENOG4108UYE	Lactoylglutathione lyase
AP033_20525	ENOG4105CSM	endonuclease III
AP033_20526	ENOG4105DZB	Electron transport complex
AP033_20527	ENOG4108UQQ	Electron transport complex
AP033_20528	ENOG4105D6A	Electron transport complex
AP033_20530	ENOG4108R3D	Electron transport complex
AP033_20533	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AP033_20534	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AP033_20536	ENOG4105CHW	UPF0052 protein
AP033_20537	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AP033_20538	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AP033_20539	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AP033_20540	ENOG4105M00	molybdopterin converting factor, subunit 1
AP033_20541	ENOG4108ZAF	Molybdopterin
AP033_20542	ENOG4105BZU	Histidine kinase
AP033_20545	ENOG4108I5U	Uridine phosphorylase
AP033_20546	ENOG4108I5U	Uridine phosphorylase
AP033_20548	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AP033_20549	ENOG4105D1F	ATP-binding protein
AP033_20550	ENOG4105DBI	uridine monophosphokinase
AP033_20551	ENOG4108GAE	asmA family
AP033_20552	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
AP033_20554	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AP033_20555	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AP033_20558	ENOG4105CHU	acetyl-coa acetyltransferase
AP033_20559	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AP033_20560	ENOG41069NU	Nitroreductase
AP033_20561	ENOG4105EJC	lysr family transcriptional regulator
AP033_20562	ENOG4105I93	response regulator
AP033_20564	ENOG4105WD1	Membrane
AP033_20565	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AP033_20566	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AP033_20567	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AP033_20568	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AP033_20569	ENOG4105KRS	Proteinase inhibitor
AP033_20571	ENOG4105UBK	short-chain dehydrogenase reductase
AP033_20572	ENOG4105ERU	peptidase
AP033_20574	ENOG4108XM1	transcriptional regulator AsnC family
AP033_20575	ENOG4105C29	acyl-CoA thioesterase
AP033_20579	ENOG4105BZU	Histidine kinase
AP033_20580	ENOG41082YX	Transcriptional regulator, arsr family
AP033_20581	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AP033_20586	ENOG4108V1U	phospholipid-binding protein
AP033_20587	ENOG4108V1U	phospholipid-binding protein
AP033_20590	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AP033_20593	ENOG4107YTP	response regulator receiver protein
AP033_20595	ENOG4105BZU	Histidine kinase
AP033_20596	ENOG4105BZU	Histidine kinase
AP033_20597	ENOG4105BZU	Histidine kinase
AP033_20598	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AP033_20601	ENOG4107QSI	ABC, transporter
AP033_20602	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AP033_20603	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AP033_20604	ENOG4105C3U	ABC transporter
AP033_20605	ENOG4108JQ7	(ABC) transporter
AP033_20606	ENOG4105CHF	Glutathione S-transferase
AP033_20607	ENOG4108DNC	Involved in acetate metabolism (By similarity)
AP033_20608	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AP033_20609	ENOG4105PQ6	UPF0208 membrane protein
AP033_20610	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
AP033_20612	ENOG4105C7J	ABC transporter, permease
AP033_20613	ENOG4108JJB	ABC transporter
AP033_20614	ENOG4105BZU	Histidine kinase
AP033_20615	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
AP033_20616	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AP033_20618	ENOG4105D1H	recombination factor protein RarA
AP033_20619	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AP033_20620	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AP033_20621	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AP033_20622	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AP033_20623	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AP033_20624	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AP033_20626	ENOG4105D0M	Protease HtpX homolog
AP033_20628	ENOG4107FW0	short-chain dehydrogenase reductase
AP033_20631	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AP033_20633	ENOG4105RHG	
AP033_20635	ENOG4107QTF	adenylosuccinate lyase
AP033_20636	ENOG41075W9	High frequency lysogenization protein HflD homolog
AP033_20637	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AP033_20638	ENOG4107RE1	Inosine-guanosine kinase
AP033_20640	ENOG4107S6Z	Na H antiporter
AP033_20641	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AP033_20642	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AP033_20643	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AP033_20644	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AP033_20645	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AP033_20646	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AP033_20647	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AP033_20648	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AP033_20649	ENOG4108R99	pseudouridine synthase
AP033_20651	ENOG4105VEQ	Cold shock protein
AP033_20652	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AP033_20653	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AP033_20655	ENOG41090BQ	Glutaredoxin
AP033_20656	ENOG4108EKI	Dehydrogenase
AP033_20657	ENOG4106KNT	transcriptional regulator
AP033_20658	ENOG4105DY8	decarboxylase
AP033_20660	ENOG4105DWU	Membrane
AP033_20665	ENOG4105CUX	Signal transduction histidine kinase
AP033_20667	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AP033_20670	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AP033_20671	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
AP033_20672	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
AP033_20673	ENOG41081XQ	Conserved Protein
AP033_20674	ENOG4105C9M	aspartyl-trna synthetase
AP033_20675	ENOG4107104	thymidine kinase
AP033_20676	ENOG4105CK2	sodium dicarboxylate symporter
AP033_20677	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AP033_20678	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AP033_20679	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AP033_20680	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AP033_20681	ENOG4105DDQ	anthranilate synthase
AP033_20682	ENOG4105CRQ	synthase (Component I)
AP033_20683	ENOG4105DB7	PHP domain protein
AP033_20684	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AP033_20685	ENOG4105FE9	pseudouridine synthase
AP033_20686	ENOG4108JJ8	(ABC) transporter
AP033_20687	ENOG4108JJ9	ABC, transporter
AP033_20688	ENOG4105C3M	thioredoxin reductase
AP033_20690	ENOG4105C9B	Cysteine desulfurase
AP033_20691	ENOG4105BZU	Histidine kinase
AP033_20692	ENOG4107GZ4	SanA protein
AP033_20694	ENOG4107R1I	NAD-dependent malic enzyme
AP033_20696	ENOG4105C8V	SAICAR synthetase
AP033_20700	ENOG4108ZG0	Ompa motb domain protein
AP033_20703	ENOG4105CQB	FAD linked oxidase domain protein
AP033_20705	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
AP033_20707	ENOG4105C84	Histidine ammonia-lyase
AP033_20708	ENOG4105CGP	Urocanate hydratase
AP033_20709	ENOG41088SP	formiminoglutamate hydrolase
AP033_20710	ENOG4105CI2	imidazolone-5-propionate hydrolase
AP033_20711	ENOG4105CZE	histidine utilization repressor
AP033_20714	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AP033_20716	ENOG4105BZU	Histidine kinase
AP033_20717	ENOG4105CQ2	DNA polymerase
AP033_20718	ENOG4105WH1	Two component transcriptional regulator luxr family
AP033_20719	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AP033_20725	ENOG4105BZU	Histidine kinase
AP033_20727	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AP033_20728	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AP033_20729	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AP033_20732	ENOG4105FQ6	thiopurine methyltransferase
AP033_20733	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AP033_20735	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
AP033_20736	ENOG41067MG	lrgb family
AP033_20738	ENOG4105CJB	Exodeoxyribonuclease I
AP033_20739	ENOG4108ETY	sodium dicarboxylate symporter
AP033_20740	ENOG4105E0X	reductase
AP033_20741	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
AP033_20742	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AP033_20743	ENOG4108YZT	Adenosylcobinamide kinase
AP033_20746	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
AP033_20747	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
AP033_20750	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_20755	ENOG4107QK7	reductase
AP033_20756	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AP033_20757	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AP033_20758	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AP033_20759	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AP033_20760	ENOG4105C72	UPF0176 protein
AP033_20762	ENOG4105S8Q	sugar efflux transporter
AP033_20764	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
AP033_20770	ENOG4105EAQ	(twin-arginine translocation) pathway signal
AP033_20771	ENOG4105C5X	domain protein
AP033_20774	ENOG4105CH5	extracellular solute-binding protein, family 7
AP033_20776	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AP033_20779	ENOG41067TZ	transcriptional regulator, MarR family
AP033_20780	ENOG4105C94	Transporter
AP033_20782	ENOG4105VZJ	PTS System
AP033_20784	ENOG4105VCP	PTS System
AP033_20785	ENOG4105F8D	glycoside hydrolase family 4
AP033_20786	ENOG410901P	UPF0249 protein
AP033_20787	ENOG41060NJ	transcriptional regulator
AP033_20788	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
AP033_20789	ENOG4105DJ9	glucan biosynthesis protein
AP033_20790	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_20793	ENOG4105CGF	Aromatic amino acid aminotransferase
AP033_20794	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AP033_20795	ENOG4105DWF	phosphomethylpyrimidine kinase
AP033_20796	ENOG4105C5S	asparaginyl-tRNA synthetase
AP033_20797	ENOG4108NVR	Methyl-accepting chemotaxis
AP033_20798	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AP033_20799	ENOG4105EJQ	L-serine dehydratase
AP033_20800	ENOG4105C44	Serine transporter
AP033_20801	ENOG4105P8F	nudix hydrolase
AP033_20802	ENOG4105CRQ	synthase (Component I)
AP033_20805	ENOG4105CM6	amino acid regulated cytosolic protein
AP033_20807	ENOG4108JU8	Transcriptional regulator
AP033_20808	ENOG4105D9U	N-acetyltransferase
AP033_20811	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AP033_20812	ENOG4108NVR	Methyl-accepting chemotaxis
AP033_20813	ENOG4105C8P	)-transporter
AP033_20814	ENOG4105BZU	Histidine kinase
AP033_20815	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AP033_20816	ENOG4108MJ5	VirK protein
AP033_20817	ENOG4105RW8	MltA-interacting MipA family protein
AP033_20818	ENOG4105EB3	Histidine kinase
AP033_20819	ENOG4107EXC	regulatoR
AP033_20824	ENOG4105C2J	ABC transporter
AP033_20825	ENOG4107SDZ	Galactoside transport system permease protein mglC
AP033_20826	ENOG4105F2I	Transposase
AP033_20831	ENOG41073TP	transcriptional regulator
AP033_20832	ENOG4105CR4	methylisocitrate lyase
AP033_20833	ENOG4105BZN	citrate synthase
AP033_20834	ENOG4108I0Z	Aconitate hydratase
AP033_20835	ENOG4105C7F	AcnD-accessory protein PrpF
AP033_20836	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AP033_20839	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AP033_20840	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AP033_20841	ENOG4105F1J	Homogentisate 1,2-dioxygenase
AP033_20843	ENOG4108RXX	maleylacetoacetate isomerase
AP033_20844	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AP033_20845	ENOG4105BZU	Histidine kinase
AP033_20847	ENOG4106TD9	Diguanylate cyclase
AP033_20848	ENOG4105DR4	Methyltransferase
AP033_20849	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
AP033_20850	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
AP033_20851	ENOG4108MN8	Membrane
AP033_20852	ENOG4105CDA	abc transporter atp-binding protein
AP033_20853	ENOG4105DRP	amino acid AbC transporter
AP033_20854	ENOG4105EZ7	amino acid ABC transporter
AP033_20855	ENOG4107QXX	ABC transporter
AP033_20857	ENOG410667J	hydrolase
AP033_20859	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AP033_20860	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AP033_20864	ENOG4105BZU	Histidine kinase
AP033_20866	ENOG4105BZU	Histidine kinase
AP033_20867	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AP033_20868	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AP033_20870	ENOG4105BZU	Histidine kinase
AP033_20875	ENOG4105CQ7	ATP-dependent helicase
AP033_20877	ENOG4105R8A	Heat shock protein
AP033_20878	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
AP033_20879	ENOG4105EJC	lysr family transcriptional regulator
AP033_20880	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AP033_20881	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AP033_20882	ENOG4105KPY	Small multidrug resistance protein
AP033_20883	ENOG4108NVR	Methyl-accepting chemotaxis
AP033_20884	ENOG4108VYJ	response regulator receiver protein
AP033_20886	ENOG4105CBS	Chea signal transduction histidine kinase
AP033_20887	ENOG4105CBS	Chea signal transduction histidine kinase
AP033_20888	ENOG4105BZU	Histidine kinase
AP033_20890	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AP033_20891	ENOG4108V3W	Chemotaxis protein, CheW
AP033_20892	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_20893	ENOG4108N3W	hemolysin secretion protein
AP033_20894	ENOG4107SDU	Methyl-accepting chemotaxis
AP033_20895	ENOG4105C1J	atp-dependent rna helicase
AP033_20898	ENOG4105CW7	secretion protein, HlyD family
AP033_20899	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AP033_20900	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_20901	ENOG4105CTD	carboxy-peptidase
AP033_20902	ENOG4108WC9	type VI secretion system effector, hcp1 family
AP033_20903	ENOG4105CS6	Rhs element vgr protein
AP033_20907	ENOG410829K	Lysine exporter protein (Lyse ygga)
AP033_20908	ENOG4105BZG	amino acid carrier protein
AP033_20911	ENOG4107RUE	extracellular solute-binding protein family 1
AP033_20912	ENOG4107RUE	extracellular solute-binding protein family 1
AP033_20913	ENOG4105D38	putrescine abc transporter
AP033_20914	ENOG4105F38	ABC transporter, permease
AP033_20915	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AP033_20919	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AP033_20920	ENOG4105Q9Y	Universal stress protein
AP033_20921	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AP033_20924	ENOG4105C59	p-type ATPase
AP033_20926	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
AP033_20929	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
AP033_20932	ENOG4105BZU	Histidine kinase
AP033_20937	ENOG4108RC6	RTX toxin
AP033_20938	ENOG4105EUK	rtx toxin RtxA
AP033_20941	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
AP033_20942	ENOG4105DAN	ATP-dependent protease
AP033_20943	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AP033_20946	ENOG4105C5H	ABC transporter
AP033_20948	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AP033_20950	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
AP033_20951	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AP033_20952	ENOG4105C7I	Dehydrogenase
AP033_20953	ENOG4105CD8	aminopeptidase N
AP033_20955	ENOG4105CN1	protease
AP033_20956	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
AP033_20957	ENOG4108ZGC	gaf domain protein
AP033_20958	ENOG4105BZ1	(ABC) transporter
AP033_20959	ENOG4105H2K	paraquat-inducible protein a
AP033_20960	ENOG4105DY2	Paraquat-inducible protein b
AP033_20961	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AP033_20962	ENOG4105QNR	S1 RNA binding domain protein
AP033_20965	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AP033_20967	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AP033_20970	ENOG4105QAX	Iron-sulfur
AP033_20971	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AP033_20973	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
AP033_20977	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AP033_20979	ENOG4105C5H	ABC transporter
AP033_20980	ENOG4105BZU	Histidine kinase
AP033_20981	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AP033_20983	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
AP033_20984	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AP033_20985	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AP033_20986	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AP033_20988	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
AP033_20989	ENOG4106IUH	DTW domain containing protein
AP033_20991	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_20992	ENOG4107TT5	NLP P60 protein
AP033_20994	ENOG4105FGM	Fructosamine kinase
AP033_20996	ENOG4107QI1	Mate efflux family protein
AP033_21001	ENOG4109015	Biopolymer transport protein exbD tolR
AP033_21007	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
AP033_21008	ENOG4108IJ9	(ABC) transporter
AP033_21009	ENOG4105E98	transcriptional regulator DeoR family
AP033_21010	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
AP033_21011	ENOG4105XEP	YhcH YjgK YiaL family protein
AP033_21012	ENOG4105M4H	endoribonuclease L-psp
AP033_21013	ENOG4105DDV	Transcriptional regulator (LacI family
AP033_21014	ENOG4105CS2	ec 3.2.1.21
AP033_21015	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AP033_21018	ENOG4107QZV	Type I secretion membrane fusion protein
AP033_21020	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AP033_21021	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AP033_21022	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AP033_21023	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AP033_21024	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AP033_21026	ENOG4105C9Q	fumarate hydratase class II
AP033_21029	ENOG4105V0I	UPF0267 protein
AP033_21032	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
AP033_21033	ENOG4105DUM	transcriptional regulator, lysR family
AP033_21034	ENOG4108TWJ	NADH dehydrogenase subunit 5
AP033_21036	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AP033_21038	ENOG4105CH6	catalase
AP033_21041	ENOG4107FQX	Alpha-acetolactate decarboxylase
AP033_21042	ENOG4105C7K	acetolactate synthase
AP033_21044	ENOG4105BZU	Histidine kinase
AP033_21045	ENOG4106TD9	Diguanylate cyclase
AP033_21046	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AP033_21047	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AP033_21048	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
AP033_21053	ENOG4105BZU	Histidine kinase
AP033_21056	ENOG4107R88	Chemotaxis protein (CheV)
AP033_21058	ENOG4106YYS	transcriptional regulatory protein
AP033_21059	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AP033_21062	ENOG4107V40	secretion protein, HlyD family
AP033_21066	ENOG4105CVG	Homoserine O-transsuccinylase
AP033_21067	ENOG41090FY	type IV pilus biogenesis stability protein PilW
AP033_21069	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
AP033_21070	ENOG4108VKG	metal-dependent hydrolase
AP033_21072	ENOG4105F04	LysR family Transcriptional regulator
AP033_21076	ENOG4105DFG	type I secretion outer membrane protein
AP033_21077	ENOG4105CDV	Ompa motb domain protein
AP033_21078	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
AP033_21079	ENOG4105E3Q	saccharopine dehydrogenase
AP033_21080	ENOG4105DY8	decarboxylase
AP033_21082	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AP033_21085	ENOG4108I0Y	(ABC) transporter
AP033_21086	ENOG4105UQX	Mate efflux family protein
AP033_21087	ENOG4105CGD	Nad-dependent epimerase dehydratase
AP033_21089	ENOG4105C2C	drug resistance transporter, Bcr CflA
AP033_21090	ENOG4105I08	Pseudouridine synthase
AP033_21091	ENOG4105CFI	type iii restriction protein res subunit
AP033_21094	ENOG4105BZU	Histidine kinase
AP033_21095	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AP033_21098	ENOG4108N3W	hemolysin secretion protein
AP033_21104	ENOG4105KXC	Collagenase
AP033_21106	ENOG4105BZU	Histidine kinase
AP033_21107	ENOG4105BZU	Histidine kinase
AP033_21108	ENOG4105CJW	magnesium transporter
AP033_21110	ENOG4105C44	Serine transporter
AP033_21112	ENOG4105CJ1	ABC, transporter
AP033_21113	ENOG4107QWP	ABC-2 type transporter
AP033_21115	ENOG4105XZD	Fe-S protein
AP033_21117	ENOG4105VNH	ABC transporter solute-binding protein
AP033_21118	ENOG4105CXZ	ABC transporter, permease
AP033_21119	ENOG4108VGW	abc transporter atp-binding protein
AP033_21120	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
AP033_21121	ENOG4108W1A	pseudouridine synthase
AP033_21122	ENOG4105C8J	)-transporter
AP033_21124	ENOG4105C28	cystathionine
AP033_21125	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AP033_21128	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AP033_21131	ENOG41087YS	Phage shock protein A
AP033_21132	ENOG4105E51	psp operon transcriptional activator
AP033_21133	ENOG4108J59	Extracellular solute-binding protein, family 5
AP033_21134	ENOG4108I5W	peptide transport system, permease protein
AP033_21135	ENOG4108EU3	peptide transport system, permease
AP033_21136	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
AP033_21137	ENOG4108JQ2	peptide transport system atp-binding protein
AP033_21140	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AP033_21145	ENOG4107QY8	reductase
AP033_21148	ENOG4105TMB	Formate nitrite transporter
AP033_21150	ENOG4108535	NAD dependent epimerase/dehydratase family
AP033_21151	ENOG4105GFG	DUF218 domain
AP033_21153	ENOG4107835	probably involved in intracellular septation (By similarity)
AP033_21154	ENOG4105NAU	thioesterase Superfamily protein
AP033_21155	ENOG4105K9H	YciI-like protein
AP033_21157	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AP033_21158	ENOG4105DZ2	Transcriptional regulator
AP033_21163	ENOG4105CCT	upf0313 protein
AP033_21164	ENOG4108VP3	Lysine exporter protein (LysE YggA)
AP033_21165	ENOG4105EW9	transcriptional regulator AsnC family
AP033_21166	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
AP033_21167	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
AP033_21168	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
AP033_21169	ENOG4106371	Methyltransferase
AP033_21170	ENOG4107S90	membrAne
AP033_21171	ENOG4106WF9	DNA-binding transcriptional regulator TorR
AP033_21172	ENOG4108SBI	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
AP033_21173	ENOG4105ETE	Transcriptional regulator (LacI family
AP033_21174	ENOG4105HP8	regulator of competence-specific genes
AP033_21178	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AP033_21179	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AP033_21180	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AP033_21181	ENOG4105RKX	Protein of unknown function (DUF2498)
AP033_21182	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AP033_21183	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AP033_21184	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AP033_21185	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AP033_21187	ENOG4107QPN	acyl-Coa dehydrogenase
AP033_21188	ENOG41067SE	Tetr family transcriptional regulator
AP033_21190	ENOG4105MTM	Protein of unknown function (DUF1496)
AP033_21191	ENOG4105C26	Dehydrogenase
AP033_21192	ENOG4108R86	Transcriptional regulator
AP033_21197	ENOG4105F1S	paraquat-inducible protein a
AP033_21198	ENOG4105DY2	Paraquat-inducible protein b
AP033_21203	ENOG4105DFP	Integrase
AP033_21204	ENOG4105DFP	Integrase
AP033_21205	ENOG4105C0D	helicase
AP033_21211	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AP033_21213	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
AP033_21214	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
AP033_21215	ENOG4105C26	Dehydrogenase
AP033_21217	ENOG4105DM4	PTS System
AP033_21218	ENOG4105DM4	PTS System
AP033_21219	ENOG4108YRF	PTS System
AP033_21221	ENOG4106R3P	AraC family transcriptional regulator
AP033_21222	ENOG4105DM4	PTS System
AP033_21223	ENOG4105EIP	mannose-6-phosphate isomerase
AP033_21224	ENOG4108RNS	Exports L-alanine (By similarity)
AP033_21225	ENOG4105BZU	Histidine kinase
AP033_21227	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AP033_21229	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AP033_21230	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AP033_21232	ENOG4105M8F	Biopolymer transport protein exbD tolR
AP033_21233	ENOG4105E02	MotA TolQ exbB proton channel
AP033_21234	ENOG4107YD3	Thioesterase
AP033_21235	ENOG4105KJB	cyd operon protein YbgE
AP033_21237	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AP033_21238	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AP033_21240	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AP033_21241	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AP033_21242	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AP033_21243	ENOG4105C8N	cysteinyl-tRNA synthetase
AP033_21244	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AP033_21245	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AP033_21246	ENOG4105D58	Diguanylate phosphodiesterase
AP033_21249	ENOG4105ZU8	porin-like protein H
AP033_21250	ENOG4105DVT	helicase
AP033_21251	ENOG4105EJ9	Membrane
AP033_21252	ENOG4108URS	primosomal replication protein n''
AP033_21253	ENOG4106428	Protein of unknown function (DUF2496)
AP033_21254	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_21255	ENOG4105CGK	Exodeoxyribonuclease III
AP033_21256	ENOG4106YG3	ABC transporter
AP033_21257	ENOG4105DSP	amino acid AbC transporter
AP033_21258	ENOG4105E89	ABC transporter
AP033_21259	ENOG4108JEH	abc transporter atp-binding protein
AP033_21262	ENOG4105C6N	Formate acetyltransferase
AP033_21264	ENOG4108N3W	hemolysin secretion protein
AP033_21265	ENOG4105F1A	Pyruvate formate-lyase
AP033_21267	ENOG4105XWI	UPF0304 protein
AP033_21268	ENOG4105CYN	Serine protein kinase
AP033_21269	ENOG4106AKX	UPF0229 protein
AP033_21270	ENOG4105ED1	spovr family
AP033_21271	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AP033_21273	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AP033_21274	ENOG4105BZ1	(ABC) transporter
AP033_21275	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
AP033_21277	ENOG4105D60	lipoprotein releasing system transmembrane protein
AP033_21278	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AP033_21279	ENOG4105D60	lipoprotein releasing system transmembrane protein
AP033_21281	ENOG4108JA2	transcriptioN-repair coupling factor
AP033_21283	ENOG4106M3D	hemolysin
AP033_21285	ENOG4105CEP	NADH dehydrogenase
AP033_21291	ENOG4105K59	histidine triad (HIT) protein
AP033_21292	ENOG4108NVR	Methyl-accepting chemotaxis
AP033_21294	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
AP033_21295	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AP033_21296	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AP033_21297	ENOG4105CNU	cell division protein FtsK
AP033_21298	ENOG4105EW9	transcriptional regulator AsnC family
AP033_21299	ENOG4105DCF	alanine dehydrogenase
AP033_21301	ENOG4107R11	Transcriptional regulator
AP033_21303	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
AP033_21304	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AP033_21305	ENOG4105CFV	Tetratricopeptide repeat protein
AP033_21306	ENOG4105Q4A	inner membrane protein yciS
AP033_21307	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AP033_21308	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AP033_21309	ENOG4105CAT	Cytidine monophosphate kinase
AP033_21310	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
AP033_21311	ENOG4105EIN	peptidylprolyl cis-trans isomerase
AP033_21312	ENOG4105K70	DNA-binding protein
AP033_21313	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AP033_21314	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AP033_21315	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AP033_21316	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AP033_21318	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AP033_21319	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AP033_21320	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
AP033_21321	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AP033_21322	ENOG4105CNG	UPF0061 protein
AP033_21325	ENOG4105BZU	Histidine kinase
AP033_21327	ENOG4108HPI	phosphatidate Cytidylyltransferase
AP033_21334	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AP033_21337	ENOG4105JQN	Transcriptional regulator
AP033_21339	ENOG4107QY8	reductase
AP033_21340	ENOG4105CUW	cytochrome C-TYPE protein
AP033_21341	ENOG410662T	chitinase
AP033_21342	ENOG4105D9N	nucleoside
AP033_21343	ENOG4105JQN	Transcriptional regulator
AP033_21344	ENOG4105CVE	Lytic murein transglycosylase
AP033_21345	ENOG4105VNG	YcgL domain-containing protein
AP033_21346	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AP033_21347	ENOG4107QMS	site-determining protein
AP033_21348	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
AP033_21354	ENOG4107S74	Lysophospholipid transporter LplT
AP033_21355	ENOG4108N3W	hemolysin secretion protein
AP033_21356	ENOG4108JCI	Transcriptional regulator
AP033_21357	ENOG4105DKK	Benzoate
AP033_21358	ENOG4105CEY	Amp-dependent synthetase and ligase
AP033_21359	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
AP033_21360	ENOG4108IPT	Naphthoate synthase
AP033_21361	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
AP033_21362	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AP033_21363	ENOG4105E4F	Isochorismate synthase
AP033_21364	ENOG4105CHM	Aminotransferase
AP033_21365	ENOG4105DK2	UPF0207 protein
AP033_21366	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AP033_21370	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
AP033_21371	ENOG4105CEY	Amp-dependent synthetase and ligase
AP033_21372	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AP033_21375	ENOG41072GX	Peptidase M22 Glycoprotease
AP033_21376	ENOG4105DVT	helicase
AP033_21378	ENOG4105CIY	formyltetrahydrofolate deformylase
AP033_21379	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AP033_21380	ENOG4105D07	Signal peptide peptidase, SppA
AP033_21381	ENOG4105HDK	L-asparaginase
AP033_21382	ENOG4105VUT	cytoplasmic protein
AP033_21384	ENOG4105E0X	reductase
AP033_21385	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AP033_21386	ENOG4105DSB	aldose 1-epimerase
AP033_21388	ENOG4105DHI	Methyltransferase
AP033_21391	ENOG4107R88	Chemotaxis protein (CheV)
AP033_21392	ENOG4105DAG	ROK family
AP033_21393	ENOG4105CA9	Pyruvate kinase
AP033_21394	ENOG4108NRW	Phospholipase, patatin family
AP033_21397	ENOG4105C8J	)-transporter
AP033_21399	ENOG4105CI1	PTS System
AP033_21400	ENOG4105F8V	Hydrolase, tatD family
AP033_21401	ENOG4107QRG	dna polymerase iii
AP033_21402	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AP033_21403	ENOG4105HHA	aminodeoxychorismate lyase
AP033_21404	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
AP033_21405	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AP033_21406	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AP033_21407	ENOG4105CHR	reductase
AP033_21408	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AP033_21409	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AP033_21410	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AP033_21411	ENOG4105VGS	50s ribosomal protein l32
AP033_21412	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
AP033_21413	ENOG4108UHJ	MAF-like protein
AP033_21414	ENOG4105EI2	Pseudouridine synthase
AP033_21415	ENOG4105C03	ribonuclease
AP033_21416	ENOG4105CHH	sulfate transporter
AP033_21418	ENOG4108EKI	Dehydrogenase
AP033_21419	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AP033_21420	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AP033_21421	ENOG4105DFD	Na H antiporter
AP033_21423	ENOG4106V8H	Nucleoid-associated protein
AP033_21425	ENOG4105E68	Sulfatase
AP033_21440	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AP033_21442	ENOG4105WXW	Antirepressor
AP033_21468	ENOG4105F2I	Transposase
AP033_21476	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AP033_21477	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AP033_21481	ENOG4105DGU	Histone deacetylase
AP033_21482	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AP033_21483	ENOG4105M2J	Glutaredoxin
AP033_21484	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AP033_21487	ENOG410903C	(LipO)protein
AP033_21489	ENOG4105KWW	Biogenesis protein
AP033_21490	ENOG4107QX9	Thiol disulfide interChange protein
AP033_21491	ENOG4105DA4	cytochrome c-type biogenesis protein
AP033_21492	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AP033_21493	ENOG41067VX	Heme exporter protein
AP033_21494	ENOG41060IM	Heme exporter protein
AP033_21495	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AP033_21496	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AP033_21498	ENOG4108V3W	Chemotaxis protein, CheW
AP033_21500	ENOG4107QJE	Chromosome Partitioning Protein
AP033_21501	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AP033_21502	ENOG4105CBS	Chea signal transduction histidine kinase
AP033_21503	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
AP033_21504	ENOG4108VYJ	response regulator receiver protein
AP033_21505	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AP033_21506	ENOG4107R21	site-determining protein
AP033_21507	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AP033_21508	ENOG4105D7B	Flagellar biosynthesis protein flha
AP033_21509	ENOG4108BY2	phosphohistidine phosphatase
AP033_21510	ENOG4108JQM	Insulinase (Peptidase family M16)
AP033_21512	ENOG4105C75	arginyL-tRNA synthetase
AP033_21516	ENOG4105CE1	Ferrous iron transport protein b
AP033_21517	ENOG4105XFK	Ferrous iron transport protein A
AP033_21518	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
AP033_21519	ENOG4105NXV	High-affinity zinc uptake system protein
AP033_21520	ENOG4105FDK	ABC transporter
AP033_21521	ENOG4105FAV	ABC, transporter
AP033_21522	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AP033_21523	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AP033_21524	ENOG4105C7S	Dehydrogenase
AP033_21525	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AP033_21526	ENOG4105E33	succinate dehydrogenase
AP033_21527	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AP033_21528	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
AP033_21529	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
AP033_21530	ENOG4105BZN	citrate synthase
AP033_21531	ENOG4107QNR	UPF0135 protein
AP033_21533	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
AP033_21534	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
AP033_21535	ENOG4105EV9	Alpha Beta Hydrolase
AP033_21537	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
AP033_21538	ENOG41067MG	lrgb family
AP033_21539	ENOG4105VAW	lrga family
AP033_21540	ENOG4105CMU	LysR family (Transcriptional regulator
AP033_21542	ENOG41090R7	Ferric uptake
AP033_21543	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AP033_21544	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
AP033_21545	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AP033_21546	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
AP033_21547	ENOG4105Q8W	reductase
AP033_21548	ENOG4105MH2	YfcL protein
AP033_21549	ENOG4108BPE	-transporting atpase
AP033_21550	ENOG4105EN6	Membrane
AP033_21551	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AP033_21552	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AP033_21554	ENOG4105D00	flagellar biosynthetic protein flhB
AP033_21555	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AP033_21556	ENOG4105VS8	Flagellar biosynthetic protein fliq
AP033_21557	ENOG4105CN7	Flagellar biosynthetic protein FliP
AP033_21558	ENOG4105VTB	flagellar biosynthesis protein fliO
AP033_21559	ENOG4105DD5	Flagellar motor switch protein
AP033_21560	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AP033_21561	ENOG4105X6C	Flagellar basal body-associated protein FliL
AP033_21564	ENOG4108JIR	Flagellum-specific ATP synthase
AP033_21565	ENOG4105W2B	Flagellar assembly protein
AP033_21566	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AP033_21567	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AP033_21568	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
AP033_21569	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AP033_21570	ENOG4105BZU	Histidine kinase
AP033_21571	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AP033_21572	ENOG4105MQ3	flagellar protein FliS
AP033_21574	ENOG4107W9T	flagellar hook-associated
AP033_21575	ENOG41063QE	flagellar protein FlaG
AP033_21576	ENOG4105I03	Flagellin
AP033_21577	ENOG4105I03	Flagellin
AP033_21578	ENOG4105I03	Flagellin
AP033_21579	ENOG4105EZR	dyp-type peroxidase family protein
AP033_21580	ENOG4105QZU	Inner membrane protein YfeZ
AP033_21583	ENOG4105KUZ	arsenate reductase
AP033_21584	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AP033_21587	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AP033_21588	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AP033_21590	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AP033_21591	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_21594	ENOG4105ERG	peptidase m48, ste24p
AP033_21595	ENOG4105K89	arsenate reductase
AP033_21596	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AP033_21599	ENOG4105C2W	permease
AP033_21600	ENOG4108Z66	YbaK ebsC protein
AP033_21601	ENOG4105CGH	5'-nucleotidase
AP033_21602	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AP033_21603	ENOG41063JG	Transcriptional regulator
AP033_21604	ENOG4108YY7	Invasion gene expression up-regulator SirB
AP033_21605	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AP033_21606	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AP033_21607	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AP033_21608	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
AP033_21609	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AP033_21610	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AP033_21611	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AP033_21612	ENOG4105C3G	gtp-binding protein
AP033_21629	ENOG4105I03	Flagellin
AP033_21630	ENOG4105I03	Flagellin
AP033_21633	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AP033_21634	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AP033_21635	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AP033_21636	ENOG4105CGA	flagellar basal-body rod protein FlgG
AP033_21637	ENOG4108KPB	Flagellar basal-body rod protein FlgF
AP033_21638	ENOG4105BZE	flagellar hook protein, FlgE
AP033_21639	ENOG4105W00	Flagellar hook capping protein
AP033_21640	ENOG4108ZC9	flagellar basal-body rod protein flgc
AP033_21641	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
AP033_21642	ENOG4105BZU	Histidine kinase
AP033_21643	ENOG4107R88	Chemotaxis protein (CheV)
AP033_21650	ENOG4105C0W	non-ribosomal peptide synthetase
AP033_21651	ENOG4105Q26	Siderophore-interacting protein
AP033_21652	ENOG4107RBR	Receptor
AP033_21654	ENOG4105UYK	outer membrane protein a
AP033_21655	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AP033_21656	ENOG4105C59	p-type ATPase
AP033_21658	ENOG4105E2D	ec 3.2.1.52
AP033_21659	ENOG4105MBR	gumn family
AP033_21662	ENOG4108DG9	Smr protein MutS2
AP033_21663	ENOG4105FE9	pseudouridine synthase
AP033_21664	ENOG4105BZU	Histidine kinase
AP033_21666	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AP033_21667	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AP033_21668	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AP033_21669	ENOG4105E7A	Glutamine amidotransferase
AP033_21670	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AP033_21671	ENOG4107QPN	acyl-Coa dehydrogenase
AP033_21673	ENOG4108JDX	DNA polymerase iii, epsilon subunit
AP033_21674	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AP033_21675	ENOG4105D1A	Methyltransferase
AP033_21676	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AP033_21677	ENOG4105E9H	Lytic Murein transglycosylase
AP033_21678	ENOG41068JE	domain protein
AP033_21680	ENOG4108YZA	Nitrogen regulatory protein pii
AP033_21681	ENOG4105PY6	Phenolic acid decarboxylase
AP033_21682	ENOG4105N7H	Cytochrome
AP033_21683	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AP033_21684	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AP033_21685	ENOG4105C0B	DNA polymerase III (alpha subunit)
AP033_21686	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AP033_21687	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AP033_21688	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AP033_21689	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AP033_21690	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AP033_21691	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
AP033_21693	ENOG4105DZP	Membrane-associated zinc metalloprotease
AP033_21694	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AP033_21695	ENOG4105KNE	Phosphatidate cytidylyltransferase
AP033_21696	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AP033_21697	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AP033_21698	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AP033_21699	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AP033_21700	ENOG4105CE9	30S ribosomal protein S2
AP033_21701	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AP033_21702	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AP033_21703	ENOG4108T8E	UPF0325 protein
AP033_21704	ENOG4108ZAI	phosphatidylglycerophosphatase a
AP033_21705	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AP033_21706	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AP033_21707	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AP033_21710	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AP033_21711	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AP033_21712	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AP033_21713	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AP033_21714	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
AP033_21716	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
AP033_21717	ENOG4105C7N	Xanthine uracil vitamin C permease
AP033_21718	ENOG4105CIN	aminoacyl-histidine dipeptidase
AP033_21719	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AP033_21720	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AP033_21722	ENOG4105C8J	)-transporter
AP033_21723	ENOG4105BZU	Histidine kinase
AP033_21725	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AP033_21727	ENOG4105CJ2	(LipO)protein
AP033_21728	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
AP033_21729	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AP033_21730	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AP033_21731	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AP033_21732	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AP033_21733	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AP033_21734	ENOG4105M85	Bola protein
AP033_21735	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AP033_21737	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AP033_21738	ENOG4105EYM	Major Facilitator superfamily
AP033_21740	ENOG4105K6V	RNA polymerase
AP033_21742	ENOG4105DRB	nucleoside-specific channel-forming protein
AP033_21743	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AP033_21744	ENOG4107S0N	DJ-1 family
AP033_21745	ENOG4105C9B	Cysteine desulfurase
AP033_21746	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AP033_21747	ENOG4105CUZ	uba thif-type nad fad binding protein
AP033_21748	ENOG4105CA3	membrane-bound lytic murein transglycosylase
AP033_21750	ENOG4107QZM	n-acetylglutamate synthase
AP033_21752	ENOG4107QYX	exodeoxyribonuclease v alpha
AP033_21753	ENOG4107QKA	exodeoxyribonuclease V beta
AP033_21754	ENOG4105DSY	exodeoxyribonuclease V, gamma
AP033_21757	ENOG4105X2V	dna damage-inducible protein
AP033_21758	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
AP033_21760	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AP033_21761	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AP033_21764	ENOG4108Y51	tRNA-binding protein
AP033_21765	ENOG41060NJ	transcriptional regulator
AP033_21766	ENOG4105CNT	hydrolase family 2
AP033_21768	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AP033_21769	ENOG4108IQE	Amp-dependent synthetase and ligase
AP033_21770	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AP033_21771	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AP033_21773	ENOG4105EAC	phosphoserine phosphatase
AP033_21775	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
AP033_21776	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
AP033_21777	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
AP033_21778	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AP033_21779	ENOG4105D9N	nucleoside
AP033_21780	ENOG4105EYA	deoxyribonuclease
AP033_21783	ENOG4105BZG	amino acid carrier protein
AP033_21786	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AP033_21787	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
AP033_21788	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
AP033_21789	ENOG4105D98	threonine synthase
AP033_21790	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AP033_21793	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AP033_21795	ENOG41065U4	response regulator
AP033_21796	ENOG4105BZU	Histidine kinase
AP033_21798	ENOG4105N5T	Radical SAM Protein
AP033_21801	ENOG4105CBC	glutamate synthase
AP033_21802	ENOG4105BZ8	glutamate synthase
AP033_21804	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AP033_21806	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AP033_21807	ENOG4105EN6	Membrane
AP033_21808	ENOG4105VP0	transcriptional regulator, lysR family
AP033_21809	ENOG4105EJ9	Membrane
AP033_21810	ENOG4107RRE	RNA-directed DNA polymerase
AP033_21815	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AP033_21816	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AP033_21817	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AP033_21818	ENOG4105M6F	mutator MutT protein
AP033_21819	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AP033_21821	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AP033_21822	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AP033_21823	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AP033_21824	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AP033_21825	ENOG4105DFU	Cell wall formation (By similarity)
AP033_21826	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AP033_21828	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AP033_21829	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AP033_21830	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AP033_21831	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AP033_21832	ENOG4105CJN	penicillin-binding protein
AP033_21833	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AP033_21834	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AP033_21835	ENOG4107QN2	dihydrolipoyl dehydrogenase
AP033_21836	ENOG4107QSN	dihydrolipoamide acetyltransferase
AP033_21837	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AP033_21838	ENOG41073TP	transcriptional regulator
AP033_21839	ENOG4105CGH	5'-nucleotidase
AP033_21840	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AP033_21841	ENOG4105T95	Thiol disulfide interChange protein
AP033_21842	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AP033_21843	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
AP033_21845	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AP033_21848	ENOG4107QHF	type ii secretion system protein e
AP033_21849	ENOG4105D7Q	type ii secretion system
AP033_21850	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AP033_21851	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AP033_21852	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
AP033_21853	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
AP033_21854	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AP033_21855	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AP033_21856	ENOG4105IPS	esterase
AP033_21857	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
AP033_21858	ENOG4108SX3	cytoplasmic protein
AP033_21859	ENOG41087AY	ADP-Ribose pyrophosphatase
AP033_21860	ENOG4105DFG	type I secretion outer membrane protein
AP033_21861	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AP033_21862	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AP033_21863	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_21865	ENOG4105I7R	Adenylate cyclase
AP033_21866	ENOG4107IX6	phosphate transport regulator
AP033_21867	ENOG4105CJ3	phosphate transporter
AP033_21868	ENOG4106MWK	domain protein
AP033_21871	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AP033_21872	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AP033_21873	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AP033_21874	ENOG4105DXN	mazG family
AP033_21875	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AP033_21876	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AP033_21877	ENOG4105BZU	Histidine kinase
AP033_21881	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AP033_21882	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AP033_21883	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
AP033_21884	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AP033_21885	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AP033_21886	ENOG4105C3F	Signal peptidase i
AP033_21887	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AP033_21888	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
AP033_21889	ENOG4105VQK	sigma E regulatory protein, MucB RseB
AP033_21891	ENOG4105EMN	RNA polymerase sigma factor
AP033_21892	ENOG4108IYU	L-aspartate oxidase
AP033_21894	ENOG4105Y75	tpr repeat protein
AP033_21895	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AP033_21897	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AP033_21898	ENOG4105D0A	hydroxylase
AP033_21900	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
AP033_21901	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AP033_21902	ENOG4105E66	phosphoriboisomerase A
AP033_21903	ENOG4108JQ1	Dehydrogenase
AP033_21904	ENOG4108ZP8	Acetolactate synthase small subunit
AP033_21905	ENOG4105C7K	acetolactate synthase
AP033_21906	ENOG4108IQE	Amp-dependent synthetase and ligase
AP033_21907	ENOG41064T2	transcriptional regulator, lysR family
AP033_21911	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AP033_21912	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AP033_21913	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AP033_21914	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AP033_21923	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AP033_21926	ENOG4108K5H	permease YjgP YjgQ family protein
AP033_21927	ENOG4108M8S	permease YjgP YjgQ family protein
AP033_21928	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AP033_21929	ENOG4105MYG	DNA polymerase iii, chi subunit
AP033_21930	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AP033_21931	ENOG4105C5I	Dehydrogenase
AP033_21932	ENOG4105D3G	Pseudouridine synthase
AP033_21933	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
AP033_21934	ENOG4108IAB	Phoh family
AP033_21935	ENOG4105DBV	ornithine carbamoyltransferase
AP033_21936	ENOG4105CXT	aspartate transcarbamylase
AP033_21937	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
AP033_21938	ENOG4105KME	endoribonuclease L-psp
AP033_21939	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
AP033_21940	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AP033_21941	ENOG4105VFK	BolA family
AP033_21943	ENOG4105E3I	toluene tolerance
AP033_21944	ENOG4107PE3	Mammalian cell entry related domain protein
AP033_21945	ENOG4105CY3	ABC transporter, permease
AP033_21946	ENOG4105DHJ	ABC, transporter
AP033_21948	ENOG4105C2X	Arabinose 5-phosphate isomerase
AP033_21949	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AP033_21951	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
AP033_21952	ENOG4108IUZ	ABC transporter
AP033_21953	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AP033_21954	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AP033_21955	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AP033_21957	ENOG41080Z8	PHOSPHOCARRIER protein
AP033_21958	ENOG4105CJW	magnesium transporter
AP033_21959	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AP033_21960	ENOG4105N42	UPF0307 protein
AP033_21961	ENOG4107T0D	ABC, transporter
AP033_21962	ENOG4106SMU	thiamine transporter membrane protein
AP033_21963	ENOG4105DP9	ABC transporter
AP033_21964	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
AP033_21965	ENOG4105DFU	Cell wall formation (By similarity)
AP033_21966	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AP033_21967	ENOG4105F0N	pyrophosphate phospho-hydrolase
AP033_21968	ENOG41066HZ	AIG2-like family
AP033_21970	ENOG4105CFU	surface antigen
AP033_21971	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AP033_21972	ENOG4108UUE	Transcriptional regulator
AP033_21975	ENOG4105C19	ABC transporter
AP033_21979	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
AP033_21980	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AP033_21981	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AP033_21982	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AP033_21983	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
AP033_21985	ENOG4105C1J	atp-dependent rna helicase
AP033_21986	ENOG4107YB6	acetyltransferase, (GNAT) family
AP033_21987	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AP033_21988	ENOG4108UBT	opacity-associated protein
AP033_21989	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AP033_21990	ENOG4108RS6	transposase
AP033_21992	ENOG4108ZT0	50S ribosomal protein l17
AP033_21993	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AP033_21994	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AP033_21995	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AP033_21996	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AP033_21998	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AP033_21999	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AP033_22000	ENOG4105VPB	50S ribosomal protein L30
AP033_22001	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AP033_22002	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AP033_22003	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AP033_22004	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AP033_22005	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AP033_22006	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AP033_22007	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AP033_22008	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AP033_22009	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AP033_22010	ENOG41083MP	50s ribosomal protein l29
AP033_22011	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AP033_22012	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AP033_22013	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AP033_22014	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AP033_22015	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AP033_22016	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AP033_22017	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AP033_22018	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AP033_22019	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AP033_22020	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AP033_22021	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AP033_22022	ENOG4105E68	Sulfatase
AP033_22023	ENOG4108UV7	flagellar protein motX
AP033_22024	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AP033_22025	ENOG4105D44	asparaginase
AP033_22026	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AP033_22030	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
AP033_22031	ENOG4105C5H	ABC transporter
AP033_22033	ENOG4105DNZ	Alpha Beta Hydrolase
AP033_22035	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
AP033_22036	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AP033_22038	ENOG4105C26	Dehydrogenase
AP033_22040	ENOG4105C8Y	Acetylornithine aminotransferase
AP033_22041	ENOG4105DDQ	anthranilate synthase
AP033_22042	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AP033_22045	ENOG4105C31	Tryptophanyl-tRNA synthetase
AP033_22046	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AP033_22047	ENOG4105DJV	ribulose-phosphate 3-epimerase
AP033_22048	ENOG4105DFE	Dna adenine methylase
AP033_22050	ENOG4105D49	3-dehydroquinate synthase
AP033_22051	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AP033_22052	ENOG4105E4G	Type IV pilus
AP033_22057	ENOG4108JQC	penicillin-binding protein 1A
AP033_22059	ENOG4105EHV	domain protein
AP033_22060	ENOG4107QN2	dihydrolipoyl dehydrogenase
AP033_22062	ENOG4105CH7	arginosuccinase
AP033_22063	ENOG4105CDH	Citrulline--aspartate ligase
AP033_22064	ENOG4105CAS	nag kinase
AP033_22065	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AP033_22066	ENOG4105CWC	Acetylornithine deacetylase
AP033_22067	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AP033_22069	ENOG4105D7W	serine acetyltransferase
AP033_22070	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AP033_22071	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AP033_22072	ENOG4107YZP	Rhodanese domain protein
AP033_22073	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
AP033_22075	ENOG4105E33	succinate dehydrogenase
AP033_22076	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
AP033_22077	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
AP033_22078	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AP033_22079	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AP033_22081	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AP033_22082	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AP033_22087	ENOG4105CP7	Triose-phosphate isomerase
AP033_22089	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AP033_22090	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
AP033_22091	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AP033_22092	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AP033_22093	ENOG41063M6	Cell Division Protein
AP033_22094	ENOG4105ETE	Transcriptional regulator (LacI family
AP033_22095	ENOG4105C25	Primosomal protein n'
AP033_22096	ENOG4105VFB	Binds the 23S rRNA (By similarity)
AP033_22097	ENOG4105C6K	Malic enzyme
AP033_22098	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
AP033_22099	ENOG4105C28	cystathionine
AP033_22100	ENOG4105CFH	Aspartokinase
AP033_22101	ENOG4105SYT	Methylenetetrahydrofolate reductase
AP033_22102	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
AP033_22103	ENOG4105CBT	Fructose-1,6-bisphosphatase
AP033_22104	ENOG4105CTQ	phosphohexokinase
AP033_22105	ENOG41076HS	cation diffusion facilitator family transporter
AP033_22107	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AP033_22108	ENOG4105E0F	Histidine kinase
AP033_22110	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AP033_22111	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
AP033_22112	ENOG4105BZU	Histidine kinase
AP033_22113	ENOG4108IJ0	Aspartate ammonia-lyase
AP033_22114	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
AP033_22116	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AP033_22118	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
AP033_22120	ENOG4107QN1	sodium solute
AP033_22121	ENOG4105EX9	Membrane
AP033_22122	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AP033_22123	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AP033_22124	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AP033_22125	ENOG4105CB5	ATP-dependent DNA helicase recG
AP033_22126	ENOG4105C2W	permease
AP033_22127	ENOG4105E0F	Histidine kinase
AP033_22128	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AP033_22129	ENOG4108KHX	Diguanylate cyclase
AP033_22130	ENOG4108RRZ	Transcription elongation factor GreB
AP033_22131	ENOG4105BZM	domain protein
AP033_22133	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AP033_22134	ENOG4105MJ2	Competence protein
AP033_22135	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
AP033_22136	ENOG4107RK2	ADP-ribose diphosphatase NudE
AP033_22137	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AP033_22138	ENOG4105PIC	general secretion pathway protein N
AP033_22139	ENOG4105U1E	general secretion pathway protein M
AP033_22140	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
AP033_22141	ENOG4108RTD	type II secretion system protein K
AP033_22142	ENOG4108WWZ	General secretion pathway protein J
AP033_22143	ENOG4105X5Z	General secretion pathway protein I
AP033_22144	ENOG4105VWV	general secretion pathway protein h
AP033_22145	ENOG4108VAU	general secretion pathway protein G
AP033_22146	ENOG4105D7Q	type ii secretion system
AP033_22147	ENOG4107QHF	type ii secretion system protein e
AP033_22149	ENOG4108XKW	General secretion pathway protein C
AP033_22150	ENOG4105VEJ	Heat shock protein
AP033_22151	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AP033_22152	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
AP033_22154	ENOG4105SUU	thioesterase domain
AP033_22155	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AP033_22160	ENOG4105C5F	glutamine synthetase
AP033_22162	ENOG4105CUX	Signal transduction histidine kinase
AP033_22163	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AP033_22164	ENOG4105BZU	Histidine kinase
AP033_22165	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AP033_22179	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AP033_22180	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AP033_22181	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AP033_22182	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
AP033_22185	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
AP033_22186	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AP033_22187	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AP033_22188	ENOG4105CAK	Cell division ATP-binding protein ftsE
AP033_22189	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AP033_22190	ENOG4106H78	methyltransferase
AP033_22195	ENOG4108RMU	ferritin dps family protein
AP033_22196	ENOG4105D58	Diguanylate phosphodiesterase
AP033_22197	ENOG410829K	Lysine exporter protein (Lyse ygga)
AP033_22198	ENOG4108EUD	Lysophospholipase
AP033_22199	ENOG4105DQF	Hydrolase
AP033_22202	ENOG4105BZU	Histidine kinase
AP033_22203	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
AP033_22204	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AP033_22205	ENOG4105CT0	Protein of unknown function, DUF484
AP033_22206	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AP033_22207	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AP033_22208	ENOG4105XQ6	frataxin-like protein
AP033_22209	ENOG4107T0K	Adenylate cyclase
AP033_22210	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AP033_22211	ENOG41076E6	Uroporphyrinogen-III Synthase
AP033_22212	ENOG4105ECF	c-methyltransferase
AP033_22213	ENOG410601J	HemY protein
AP033_22214	ENOG4105D4P	Coproporphyrinogen iii oxidase
AP033_22215	ENOG4105XCT	Protein of unknown function (DUF2489)
AP033_22216	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
AP033_22218	ENOG4106RE7	Cytochrome
AP033_22219	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AP033_22220	ENOG4105C2M	dna polymerase I
AP033_22222	ENOG4105D52	delta-aminolevulinic acid dehydratase
AP033_22223	ENOG4105F8V	Hydrolase, tatD family
AP033_22224	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AP033_22226	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_22227	ENOG4105X6C	Flagellar basal body-associated protein FliL
AP033_22228	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
AP033_22229	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AP033_22230	ENOG4105E55	glycerol-3-phosphate acyltransferase
AP033_22231	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AP033_22233	ENOG4107R73	Mate efflux family protein
AP033_22234	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AP033_22235	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AP033_22236	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AP033_22237	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AP033_22238	ENOG4105JC1	sterol-binding domain protein
AP033_22239	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AP033_22240	ENOG4105CGY	Dna recombination protein
AP033_22242	ENOG4105CBX	hi0933 family
AP033_22243	ENOG4108V6B	universal stress protein B
AP033_22244	ENOG41090A1	ferritin
AP033_22245	ENOG4108M6U	Universal stress protein A
AP033_22246	ENOG4105EMK	carboxylate amino acid amine transporter
AP033_22248	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
AP033_22249	ENOG4105BZU	Histidine kinase
AP033_22250	ENOG4108VVK	transcriptional Regulator, AsnC
AP033_22252	ENOG4105CNH	Multidrug resistance protein MdtL
AP033_22254	ENOG4105DC7	peptidase M24
AP033_22254	ENOG4105DC7	peptidase M24
AP033_22255	ENOG4105D41	biosynthesis protein thiH
AP033_22256	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AP033_22257	ENOG4105WHD	thiamine biosynthesis protein ThiS
AP033_22258	ENOG4105D06	uba thif-type nad fad binding protein
AP033_22260	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AP033_22261	ENOG4105WMR	Protein CrcB homolog
AP033_22268	ENOG4108Z0R	Transferase
AP033_22270	ENOG4105E2X	shikimate dehydrogenase
AP033_22271	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AP033_22272	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AP033_22273	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AP033_22274	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AP033_22275	ENOG4108WI1	Dna topoisomerase
AP033_22276	ENOG4108RPN	Protein smg homolog
AP033_22277	ENOG4105C79	DNA protecting protein DprA
AP033_22278	ENOG4108WZM	domain protein
AP033_22279	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AP033_22280	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AP033_22281	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AP033_22282	ENOG4105C1A	potassium transporter peripheral membrane
AP033_22283	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AP033_22285	ENOG4108UT2	hemolysin iii
AP033_22286	ENOG4108N23	SpoOM-related protein
AP033_22287	ENOG4105PC1	Conserved Protein
AP033_22289	ENOG4105E27	serine threonine protein kinase
AP033_22290	ENOG4108Z33	Thiol disulfide Interchange Protein
AP033_22291	ENOG4106HNH	Acyl-transferase
AP033_22292	ENOG4105C0P	Mg chelatase subunit ChlI
AP033_22295	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AP033_22296	ENOG4105C01	Dihydroxy-acid dehydratase
AP033_22297	ENOG4105C7B	Threonine dehydratase
AP033_22298	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
AP033_22300	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AP033_22303	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
AP033_22304	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AP033_22305	ENOG4105JKW	Valine--pyruvate aminotransferase
AP033_22306	ENOG4108ZNX	Heat shock protein
AP033_22309	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AP033_22310	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AP033_22311	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AP033_22312	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AP033_22313	ENOG4105EAB	amino acid AbC transporter
AP033_22314	ENOG4105E5Q	amino acid AbC transporter
AP033_22317	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AP033_22318	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AP033_22319	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AP033_22320	ENOG4105QTB	Flavodoxin
AP033_22321	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AP033_22322	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AP033_22323	ENOG4107QJE	Chromosome Partitioning Protein
AP033_22324	ENOG4105FA0	parb-like partition protein
AP033_22325	ENOG410684E	atp synthase
AP033_22326	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
AP033_22327	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AP033_22328	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AP033_22329	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AP033_22330	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AP033_22331	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AP033_22332	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AP033_22333	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AP033_22335	ENOG4105CZQ	inner membrane transport protein YdhC
AP033_22336	ENOG4105F52	Transcriptional regulator
AP033_22337	ENOG4105CHU	acetyl-coa acetyltransferase
AP033_22338	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AP033_22339	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AP033_22340	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AP033_22341	ENOG4108RR8	protoporphyrinogen oxidase
AP033_22349	ENOG4105EMY	transcriptional regulator
AP033_22350	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AP033_22351	ENOG4105BZS	acriflavin resistance protein
AP033_22352	ENOG410624X	efflux transporter, rnd family, mfp subunit
AP033_22353	ENOG4105Y7M	Transcriptional regulator, TetR family
AP033_22354	ENOG4105C4R	Atp-dependent dna helicase
AP033_22355	ENOG4105MPD	Cytochrome
AP033_22362	ENOG4105DEF	Extracellular solute-binding protein, family 5
AP033_22363	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AP033_22364	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AP033_22366	ENOG4105DC8	reductase
AP033_22367	ENOG4105D6S	protein involved in catabolism of external DNA
AP033_22368	ENOG4105DGW	oligopeptidase A
AP033_22369	ENOG4105C4R	Atp-dependent dna helicase
AP033_22371	ENOG4108DMH	HTH_ARAC
AP033_22372	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AP033_22373	ENOG4105FR1	rard protein
AP033_22374	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AP033_22377	ENOG4105BZ1	(ABC) transporter
AP033_22378	ENOG4105E0K	tonB-dependent siderophore receptor
AP033_22379	ENOG4105E0A	ABC, transporter
AP033_22380	ENOG4105J76	Periplasmic binding protein
AP033_22381	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
AP033_22382	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
AP033_22383	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AP033_22384	ENOG4105C5Y	PTS System
AP033_22385	ENOG4105FCK	Membrane
AP033_22387	ENOG4105DSJ	YicC domain protein
AP033_22388	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AP033_22389	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AP033_22390	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
AP033_22391	ENOG4105D1S	lipid A biosynthesis
AP033_22392	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
AP033_22393	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AP033_22394	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_22403	ENOG4105KT5	UmuD protein
AP033_22404	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AP033_22416	ENOG4105KDC	50s ribosomal protein l28
AP033_22417	ENOG4105W0E	50S ribosomal protein L33
AP033_22419	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AP033_22420	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AP033_22421	ENOG4105M5K	heptosyltransferase
AP033_22422	ENOG4106WTF	Glycosyl transferase, family 2
AP033_22423	ENOG4105DKP	glycosyl transferase, family 9
AP033_22424	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
AP033_22430	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AP033_22431	ENOG4108ST3	glycosyltransferase
AP033_22433	ENOG4105XA0	heptosyltransferase ii
AP033_22436	ENOG4107T94	Endo-14-beta-xylanase
AP033_22437	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
AP033_22438	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AP033_22439	ENOG4107QKV	phosphomannomutase
AP033_22440	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AP033_22441	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AP033_22442	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AP033_22445	ENOG4105EY8	ABC transporter
AP033_22447	ENOG4105CEY	Amp-dependent synthetase and ligase
AP033_22448	ENOG4108EKI	Dehydrogenase
AP033_22450	ENOG4108UT6	Transferase hexapeptide repeat containing protein
AP033_22451	ENOG410600T	transposase
AP033_22452	ENOG410600T	transposase
AP033_22457	ENOG4105D3Q	Sugar transferase
AP033_22458	ENOG4105CY0	Metallo-Beta-Lactamase
AP033_22459	ENOG4105CUY	Mechanosensitive ion channel
AP033_22460	ENOG4108RG0	uracil-dna glycosylase
AP033_22461	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
AP033_22462	ENOG4105R2J	Conserved Protein
AP033_22463	ENOG4105EIP	mannose-6-phosphate isomerase
AP033_22464	ENOG4105DKQ	ROK family
AP033_22466	ENOG4105K70	DNA-binding protein
AP033_22468	ENOG4105C12	Phosphoribosylglycinamide synthetase
AP033_22469	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AP033_22470	ENOG4105W1Y	Transcriptional regulator
AP033_22471	ENOG4108M3R	transcriptional activator CadC
AP033_22472	ENOG4105D5Q	Arginine ornithine antiporter
AP033_22473	ENOG4105CXN	decarboxylase
AP033_22474	ENOG4105C8Q	Methyl-accepting chemotaxis
AP033_22476	ENOG4105E0K	tonB-dependent siderophore receptor
AP033_22477	ENOG4108UHU	Aldolase
AP033_22478	ENOG4105C6Z	Gluconate
AP033_22479	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
AP033_22480	ENOG4105C01	Dihydroxy-acid dehydratase
AP033_22481	ENOG4105DIQ	Transcriptional regulator
AP033_22482	ENOG4107R3N	Filamentation induced by cAMP protein fic
AP033_22483	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AP033_22484	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AP033_22485	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AP033_22486	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AP033_22487	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AP033_22488	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AP033_22489	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AP033_22492	ENOG4105D8G	Major Facilitator superfamily
AP033_22493	ENOG4105BZU	Histidine kinase
AP033_22494	ENOG4105C9X	ppx gppa phosphatase
AP033_22495	ENOG4105C1J	atp-dependent rna helicase
AP033_22496	ENOG4105K63	Thioredoxin
AP033_22497	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AP033_22499	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AP033_22501	ENOG4107QK7	reductase
AP033_22508	ENOG4105JIM	Phosphatidylserine synthase
AP033_22510	ENOG4105D4A	Cell wall formation (By similarity)
AP033_22511	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AP033_22512	ENOG4105CS9	pantothenic acid kinase
AP033_22517	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AP033_22518	ENOG4105PM1	preprotein translocase subunit SecE
AP033_22519	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AP033_22520	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AP033_22521	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AP033_22522	ENOG4108VZM	50s ribosomal protein L10
AP033_22523	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AP033_22524	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AP033_22525	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AP033_22526	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
AP033_22527	ENOG4105E09	nadh pyrophosphatase
AP033_22528	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AP033_22529	ENOG41062JF	Transcriptional regulator
AP033_22531	ENOG41063SB	peptidase
AP033_22532	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AP033_22534	ENOG4105C8P	)-transporter
AP033_22535	ENOG4105DJ4	phosphatidylserine decarboxylase
AP033_22536	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AP033_22537	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AP033_22547	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AP033_22548	ENOG4105K8N	protein family UPF0079, ATPase
AP033_22549	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AP033_22550	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AP033_22551	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AP033_22552	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AP033_22553	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AP033_22554	ENOG4107QJR	hflk protein
AP033_22555	ENOG4105EPW	hflc protein
AP033_22557	ENOG41069P5	Protein slyX homolog
AP033_22559	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AP033_22560	ENOG4105WWK	YheO domain protein
AP033_22561	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
AP033_22562	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
AP033_22564	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AP033_22565	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AP033_22566	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AP033_22567	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AP033_22568	ENOG4105W53	bacterioferritin-associated ferredoxin
AP033_22569	ENOG4108UQY	Iron-storage protein
AP033_22570	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AP033_22571	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
AP033_22572	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AP033_22573	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AP033_22575	ENOG4105CDU	Replicative dna helicase
AP033_22576	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AP033_22577	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
AP033_22578	ENOG4107QP8	phosphohexose isomerase
AP033_22581	ENOG4105MYN	Zinc uptake regulation protein
AP033_22582	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AP033_22583	ENOG4105P4Z	Phage shock protein G
AP033_22586	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AP033_22587	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AP033_22588	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AP033_22595	ENOG4105EEQ	Na H antiporter
AP033_22596	ENOG4105C3R	Methionine synthase
AP033_22597	ENOG4105CFH	Aspartokinase
AP033_22598	ENOG4105C5R	Aminotransferase
AP033_22600	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AP033_22601	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AP033_22602	ENOG41086KC	Transcriptional regulator
AP033_22603	ENOG4108UUM	single-stranded DNA-binding protein
AP033_22604	ENOG41062P1	Diguanylate cyclase phosphodiesterase
AP033_22608	ENOG4105E4G	Type IV pilus
AP033_22611	ENOG4107QHF	type ii secretion system protein e
AP033_22612	ENOG4105D7Q	type ii secretion system
AP033_22621	ENOG4105DFF	Rod shape-determining protein mreb
AP033_22622	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AP033_22623	ENOG4105VQ7	Rod shape-determining protein MreD
AP033_22624	ENOG4108Z03	MAF-like protein
AP033_22625	ENOG4105C03	ribonuclease
AP033_22626	ENOG4105QD6	exported protein
AP033_22628	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AP033_22629	ENOG4105CEU	Arginine dihydrolase
AP033_22633	ENOG41081QV	Universal stress protein
AP033_22636	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
AP033_22637	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AP033_22638	ENOG4105D5Q	Arginine ornithine antiporter
AP033_22639	ENOG4105EAH	synthase
AP033_22640	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AP033_22641	ENOG4105K46	50S ribosomal protein l27
AP033_22642	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AP033_22643	ENOG4105DWK	Membrane
AP033_22644	ENOG4107XM3	UPF0442 protein
AP033_22646	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AP033_22647	ENOG4105NWN	ApaG protein
AP033_22648	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AP033_22649	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AP033_22650	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AP033_22651	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AP033_22652	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)