locus-tag	class	description
FORC73_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FORC73_0002	COG0592	DNA-directed DNA polymerase activity
FORC73_0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FORC73_0004	COG0187	DNA topoisomerase II activity
FORC73_0006	COG0071	Belongs to the small heat shock protein (HSP20) family
FORC73_0007	COG3977	Valine--pyruvate aminotransferase
FORC73_0008	COG0751	glycine-tRNA ligase activity
FORC73_0009	COG0752	glycyl-tRNA synthetase alpha subunit
FORC73_0010	COG2119	membrane
FORC73_0012	COG0425	Belongs to the sulfur carrier protein TusA family
FORC73_0014	COG3385	transposase activity
FORC73_0015	COG0604	alcohol dehydrogenase
FORC73_0017	COG0129	dihydroxy-acid dehydratase activity
FORC73_0018	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC73_0021	COG0606	chelatase, subunit chli
FORC73_0022	COG0204	Acyl-transferase
FORC73_0023	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC73_0024	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC73_0026	COG3084	Protein conserved in bacteria
FORC73_0027	COG4326	sporulation control protein
FORC73_0028	COG1272	protein, Hemolysin III
FORC73_0030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC73_0031	COG0569	domain protein
FORC73_0032	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC73_0032	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC73_0033	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC73_0034	COG0242	peptide deformylase activity
FORC73_0035	COG1652	LysM domain
FORC73_0036	COG0758	DNA mediated transformation
FORC73_0037	COG2922	Belongs to the Smg family
FORC73_0038	COG0551	DNA topoisomerase type I activity
FORC73_0039	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FORC73_0040	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FORC73_0041	COG0009	L-threonylcarbamoyladenylate synthase
FORC73_0042	COG0408	coproporphyrinogen oxidase activity
FORC73_0043	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FORC73_0045	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC73_0046	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FORC73_0047	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FORC73_0049	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC73_0050	COG2104	thiamine diphosphate biosynthetic process
FORC73_0051	COG2022	thiamine diphosphate biosynthetic process
FORC73_0052	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FORC73_0054	COG0006	proline dipeptidase activity
FORC73_0054	COG0006	proline dipeptidase activity
FORC73_0058	COG1522	sequence-specific DNA binding
FORC73_0059	COG5002	protein histidine kinase activity
FORC73_0059	COG5001	Diguanylate cyclase
FORC73_0060	COG0742	ribosomal rna small subunit methyltransferase
FORC73_0062	COG0697	spore germination
FORC73_0063	COG0589	response to stress
FORC73_0064	COG1528	Iron-storage protein
FORC73_0066	COG2081	HI0933 family
FORC73_0068	COG1322	Protein conserved in bacteria
FORC73_0069	COG2226	methyltransferase
FORC73_0071	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FORC73_0072	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC73_0073	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC73_0074	COG0805	protein transport
FORC73_0075	COG1858	cytochrome C peroxidase
FORC73_0076	COG0534	Mate efflux family protein
FORC73_0078	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FORC73_0079	COG2937	Belongs to the GPAT DAPAT family
FORC73_0080	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FORC73_0081	COG3161	chorismate lyase activity
FORC73_0082	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC73_0083	COG0840	transmembrane signaling receptor activity
FORC73_0085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC73_0086	COG0084	hydrolase, TatD family'
FORC73_0089	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC73_0089	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC73_0090	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FORC73_0093	COG3078	GTPase activator activity
FORC73_0095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC73_0096	COG3071	HemY protein
FORC73_0097	COG2959	enzyme of heme biosynthesis
FORC73_0098	COG1587	Uroporphyrinogen-III synthase
FORC73_0099	COG0181	hydroxymethylbilane synthase activity
FORC73_0100	COG3072	Adenylate cyclase
FORC73_0101	COG1965	Belongs to the frataxin family
FORC73_0102	COG0019	diaminopimelate decarboxylase activity
FORC73_0103	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FORC73_0105	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FORC73_0106	COG1011	Hydrolase
FORC73_0107	COG3287	FIST C domain
FORC73_0107	COG2200	EAL domain
FORC73_0107	COG2199	diguanylate cyclase activity
FORC73_0110	COG0561	phosphatase activity
FORC73_0111	COG2267	carboxylic ester hydrolase activity
FORC73_0112	COG1280	lysine exporter protein (LysE YggA)
FORC73_0113	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC73_0114	COG0783	Belongs to the Dps family
FORC73_0120	COG0742	ribosomal rna small subunit methyltransferase
FORC73_0121	COG0552	protein localization to endoplasmic reticulum
FORC73_0122	COG2884	Cell division ATP-binding protein ftsE
FORC73_0123	COG2177	Part of the ABC transporter FtsEX involved in
FORC73_0124	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC73_0125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC73_0128	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC73_0129	COG4206	TonB-dependent receptor
FORC73_0132	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FORC73_0134	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FORC73_0135	COG5001	Diguanylate cyclase
FORC73_0135	COG3300	MHYT domain
FORC73_0137	COG3852	Histidine kinase
FORC73_0139	COG0174	glutamine synthetase
FORC73_0144	COG1490	D-aminoacyl-tRNA deacylase activity
FORC73_0145	COG0456	acetyltransferase
FORC73_0147	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FORC73_0148	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FORC73_0149	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC73_0150	COG3031	protein transport across the cell outer membrane
FORC73_0152	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC73_0153	COG1459	type II secretion system
FORC73_0154	COG2165	general secretion pathway protein
FORC73_0155	COG2165	general secretion pathway protein
FORC73_0156	COG2165	general secretion pathway protein
FORC73_0157	COG4795	General secretion pathway protein
FORC73_0158	COG3156	type II secretion system protein K
FORC73_0159	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC73_0160	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC73_0162	COG1218	3'(2'),5'-bisphosphate nucleotidase
FORC73_0163	COG0494	nUDIX hydrolase
FORC73_0164	COG0316	Belongs to the HesB IscA family
FORC73_0164	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FORC73_0165	COG1040	competence protein
FORC73_0166	COG0596	Alpha beta hydrolase
FORC73_0168	COG2183	response to ionizing radiation
FORC73_0169	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC73_0174	COG1129	ABC transporter
FORC73_0175	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC73_0176	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC73_0178	COG0745	RESPONSE REGULATOR receiver
FORC73_0180	COG2233	PERMEase
FORC73_0181	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC73_0182	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC73_0183	COG1758	RNA polymerase activity
FORC73_0184	COG0194	GDP metabolic process
FORC73_0185	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FORC73_0186	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC73_0188	COG3263	regulation of cellular component size
FORC73_0190	COG4232	protein-disulfide reductase activity
FORC73_0192	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC73_0193	COG1027	Aspartate ammonia-lyase
FORC73_0194	COG3706	GGDEF domain
FORC73_0195	COG3030	protein affecting phage T7 exclusion by the F plasmid
FORC73_0196	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC73_0198	COG2205	protein histidine kinase activity
FORC73_0199	COG0745	RESPONSE REGULATOR receiver
FORC73_0201	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FORC73_0202	COG0205	6-phosphofructokinase activity
FORC73_0203	COG1494	fructose-1,6-bisphosphatase
FORC73_0204	COG3074	FtsZ-dependent cytokinesis
FORC73_0205	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FORC73_0206	COG0460	homoserine dehydrogenase
FORC73_0206	COG0527	aspartate kinase activity
FORC73_0207	COG0626	cystathionine gamma-synthase activity
FORC73_0208	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FORC73_0209	COG0281	malic enzyme
FORC73_0210	COG0254	rRNA binding
FORC73_0211	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC73_0212	COG1609	Transcriptional regulator
FORC73_0213	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC73_0214	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FORC73_0215	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FORC73_0216	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC73_0217	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FORC73_0219	COG0149	triose-phosphate isomerase activity
FORC73_0224	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC73_0225	COG0459	protein refolding
FORC73_0226	COG3344	reverse transcriptase
FORC73_0229	COG1509	lysine 2,3-aminomutase activity
FORC73_0230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC73_0231	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC73_0232	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC73_0233	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC73_0234	COG1053	succinate dehydrogenase
FORC73_0235	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FORC73_0236	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC73_0237	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FORC73_0238	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FORC73_0239	COG1045	serine acetyltransferase
FORC73_0241	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FORC73_0242	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC73_0243	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FORC73_0244	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FORC73_0245	COG0137	argininosuccinate synthase activity
FORC73_0246	COG0165	Argininosuccinate lyase
FORC73_0248	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC73_0249	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC73_0249	COG0678	peroxiredoxin activity
FORC73_0251	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC73_0257	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FORC73_0258	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FORC73_0260	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FORC73_0261	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC73_0262	COG0546	phosphoglycolate phosphatase activity
FORC73_0263	COG0180	Tryptophanyl-tRNA synthetase
FORC73_0266	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC73_0268	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC73_0272	COG3385	transposase activity
FORC73_0273	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC73_0274	COG3954	Phosphoribulokinase
FORC73_0276	COG0429	hydrolase of the alpha beta-hydrolase fold
FORC73_0278	COG0488	(ABC) transporter
FORC73_0279	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC73_0282	COG1047	Peptidyl-prolyl cis-trans
FORC73_0284	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORC73_0285	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FORC73_0288	COG0557	exoribonuclease II activity
FORC73_0289	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC73_0290	COG0051	transcription antitermination factor activity, RNA binding
FORC73_0291	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FORC73_0292	COG0088	Forms part of the polypeptide exit tunnel
FORC73_0293	COG0089	rRNA binding
FORC73_0294	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FORC73_0295	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FORC73_0296	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FORC73_0297	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FORC73_0298	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FORC73_0299	COG0255	Belongs to the universal ribosomal protein uL29 family
FORC73_0300	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FORC73_0301	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FORC73_0302	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FORC73_0303	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FORC73_0304	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FORC73_0305	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FORC73_0306	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FORC73_0307	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FORC73_0308	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FORC73_0309	COG1841	ribosomal large subunit assembly
FORC73_0310	COG0200	Binds to the 23S rRNA
FORC73_0311	COG0201	protein transport
FORC73_0313	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FORC73_0314	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FORC73_0315	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FORC73_0316	COG0202	RNA polymerase activity
FORC73_0317	COG0203	ribosomal protein L17
FORC73_0319	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC73_0320	COG3266	domain, Protein
FORC73_0320	COG3061	Opacity-associated protein A
FORC73_0321	COG0697	spore germination
FORC73_0322	COG2153	protein acetylation
FORC73_0323	COG0513	Belongs to the DEAD box helicase family
FORC73_0325	COG0737	Belongs to the 5'-nucleotidase family
FORC73_0326	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC73_0326	COG1648	precorrin-2 dehydrogenase activity
FORC73_0327	COG0175	sulfate reduction
FORC73_0328	COG2895	sulfate adenylyltransferase (ATP) activity
FORC73_0329	COG0529	Catalyzes the synthesis of activated sulfate
FORC73_0333	COG1136	(ABC) transporter
FORC73_0333	COG0577	efflux transmembrane transporter activity
FORC73_0336	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FORC73_0337	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC73_0338	COG0729	surface antigen
FORC73_0340	COG2105	PFAM AIG2 family protein
FORC73_0341	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FORC73_0342	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FORC73_0343	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC73_0344	COG0163	prenyltransferase activity
FORC73_0345	COG4143	(ABC) transporter
FORC73_0346	COG1178	ABC-type Fe3 transport system permease component
FORC73_0347	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FORC73_0348	COG3028	Belongs to the UPF0307 family
FORC73_0349	COG0312	modulator of DNA gyrase
FORC73_0350	COG3385	transposase activity
FORC73_0351	COG2239	Acts as a magnesium transporter
FORC73_0352	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC73_0354	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC73_0355	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC73_0357	COG1137	ATPase activity
FORC73_0358	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FORC73_0361	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FORC73_0361	COG0517	IMP dehydrogenase activity
FORC73_0363	COG1127	ABC transporter
FORC73_0364	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FORC73_0365	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC73_0366	COG2854	intermembrane phospholipid transfer
FORC73_0368	COG5007	Belongs to the BolA IbaG family
FORC73_0369	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FORC73_0370	COG0204	Acyl-transferase
FORC73_0371	COG0251	oxidation-reduction process
FORC73_0372	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FORC73_0373	COG0540	Belongs to the ATCase OTCase family
FORC73_0374	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FORC73_0375	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FORC73_0377	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC73_0378	COG0564	pseudouridine synthase activity
FORC73_0379	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC73_0380	COG0525	valine-tRNA ligase activity
FORC73_0381	COG2927	DNA polymerase III (CHI subunit)
FORC73_0382	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC73_0383	COG0795	lipopolysaccharide-transporting ATPase activity
FORC73_0384	COG0795	lipopolysaccharide-transporting ATPase activity
FORC73_0386	COG3437	response regulator, receiver
FORC73_0388	COG0066	3-isopropylmalate dehydratase activity
FORC73_0389	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FORC73_0390	COG0473	3-isopropylmalate dehydrogenase activity
FORC73_0391	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FORC73_0395	COG0583	DNA-binding transcription factor activity
FORC73_0396	COG1022	Amp-dependent synthetase and ligase
FORC73_0397	COG0028	Belongs to the TPP enzyme family
FORC73_0398	COG0440	acetolactate synthase activity
FORC73_0399	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC73_0400	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FORC73_0401	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORC73_0402	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FORC73_0404	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC73_0405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC73_0407	COG0354	folic acid binding
FORC73_0408	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FORC73_0410	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC73_0411	COG1595	DNA-templated transcription, initiation
FORC73_0413	COG3026	antisigma factor binding
FORC73_0414	COG3086	response to oxidative stress
FORC73_0415	COG0481	GTPase activity
FORC73_0416	COG0681	Belongs to the peptidase S26 family
FORC73_0417	COG0571	ribonuclease III activity
FORC73_0418	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FORC73_0419	COG1381	Involved in DNA repair and RecF pathway recombination
FORC73_0420	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FORC73_0421	COG0736	holo-[acyl-carrier-protein] synthase activity
FORC73_0427	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC73_0428	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC73_0429	COG3956	TIGRFAM MazG family protein
FORC73_0430	COG0504	CTP synthase activity
FORC73_0431	COG0148	phosphopyruvate hydratase activity
FORC73_0432	COG0617	tRNA 3'-terminal CCA addition
FORC73_0433	COG3409	Peptidoglycan-binding domain 1 protein
FORC73_0433	COG3267	Type II secretory pathway component ExeA
FORC73_0435	COG4991	sh3 domain protein
FORC73_0436	COG0306	phosphate transporter
FORC73_0437	COG1392	Phosphate transport regulator
FORC73_0438	COG3025	triphosphatase activity
FORC73_0439	COG0840	transmembrane signaling receptor activity
FORC73_0440	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FORC73_0441	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FORC73_0441	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FORC73_0442	COG1538	Outer membrane efflux protein
FORC73_0443	COG0494	nUDIX hydrolase
FORC73_0444	COG3151	Protein conserved in bacteria
FORC73_0446	COG3150	esterase
FORC73_0447	COG0187	DNA topoisomerase II activity
FORC73_0448	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FORC73_0449	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FORC73_0450	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FORC73_0451	COG0237	dephospho-CoA kinase activity
FORC73_0453	COG1459	type II secretion system
FORC73_0454	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC73_0458	COG0716	FMN binding
FORC73_0459	COG4974	Belongs to the 'phage' integrase family
FORC73_0460	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC73_0461	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC73_0462	COG0737	Belongs to the 5'-nucleotidase family
FORC73_0463	COG2186	Transcriptional regulator
FORC73_0464	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FORC73_0465	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC73_0466	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC73_0467	COG0275	rRNA processing
FORC73_0468	COG3116	cell division
FORC73_0469	COG0768	penicillin binding
FORC73_0470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FORC73_0471	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC73_0472	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC73_0473	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FORC73_0474	COG0772	Belongs to the SEDS family
FORC73_0475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FORC73_0476	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC73_0477	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FORC73_0478	COG0849	cell division
FORC73_0479	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC73_0480	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FORC73_0482	COG0653	protein targeting
FORC73_0484	COG0494	nUDIX hydrolase
FORC73_0485	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FORC73_0487	COG0505	Belongs to the CarA family
FORC73_0488	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FORC73_0492	COG4172	Belongs to the ABC transporter superfamily
FORC73_0495	COG0730	response to heat
FORC73_0496	COG0583	DNA-binding transcription factor activity
FORC73_0497	COG2860	membrane
FORC73_0498	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC73_0500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC73_0502	COG0493	'glutamate synthase
FORC73_0503	COG0067	glutamate synthase
FORC73_0503	COG0069	glutamate synthase activity
FORC73_0503	COG0070	glutamate synthase
FORC73_0505	COG0069	glutamate synthase activity
FORC73_0505	COG0070	glutamate synthase
FORC73_0505	COG0067	glutamate synthase
FORC73_0506	COG1242	4 iron, 4 sulfur cluster binding
FORC73_0507	COG2203	Gaf domain
FORC73_0507	COG4251	negative regulation of phosphorylation
FORC73_0507	COG5001	Diguanylate cyclase
FORC73_0507	COG3706	GGDEF domain
FORC73_0508	COG0784	Response regulator, receiver
FORC73_0508	COG2198	Histidine kinase
FORC73_0508	COG5002	protein histidine kinase activity
FORC73_0509	COG0745	RESPONSE REGULATOR receiver
FORC73_0511	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FORC73_0514	COG0083	homoserine kinase activity
FORC73_0515	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FORC73_0516	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FORC73_0517	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FORC73_0518	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FORC73_0521	COG1115	amino acid carrier protein
FORC73_0523	COG0084	hydrolase, TatD family'
FORC73_0524	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC73_0526	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FORC73_0527	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FORC73_0528	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FORC73_0529	COG0813	purine-nucleoside phosphorylase activity
FORC73_0530	COG3385	transposase activity
FORC73_0532	COG0560	Phosphoserine phosphatase
FORC73_0534	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC73_0535	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC73_0536	COG1022	Amp-dependent synthetase and ligase
FORC73_0539	COG3250	beta-galactosidase activity
FORC73_0540	COG1609	Transcriptional regulator
FORC73_0541	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC73_0544	COG0569	domain protein
FORC73_0544	COG0189	ligase activity
FORC73_0545	COG0456	acetyltransferase
FORC73_0547	COG2171	N-acyltransferase activity
FORC73_0548	COG3141	response to X-ray
FORC73_0551	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FORC73_0552	COG1074	ATP-dependent DNA helicase activity
FORC73_0553	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC73_0555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FORC73_0555	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FORC73_0557	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FORC73_0558	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC73_0559	COG2166	iron-sulfur cluster assembly
FORC73_0560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC73_0561	COG0693	protein deglycase activity
FORC73_0562	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC73_0563	COG3248	Nucleoside-binding outer membrane protein
FORC73_0565	COG1595	DNA-templated transcription, initiation
FORC73_0567	COG2211	Major facilitator Superfamily
FORC73_0568	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC73_0570	COG2813	Specifically methylates the guanine in position
FORC73_0571	COG0271	Belongs to the BolA IbaG family
FORC73_0572	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC73_0573	COG1805	sodium ion transport
FORC73_0574	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC73_0575	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC73_0576	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC73_0577	COG2871	sodium ion transport
FORC73_0578	COG1477	protein flavinylation
FORC73_0580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FORC73_0582	COG3706	GGDEF domain
FORC73_0583	COG0733	neurotransmitter:sodium symporter activity
FORC73_0584	COG3385	transposase activity
FORC73_0586	COG0189	ligase activity
FORC73_0587	COG4067	protein conserved in archaea
FORC73_0587	COG0189	ligase activity
FORC73_0588	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC73_0589	COG2252	PERMEase
FORC73_0590	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FORC73_0593	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FORC73_0594	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FORC73_0595	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FORC73_0596	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC73_0596	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC73_0599	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FORC73_0600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC73_0601	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FORC73_0602	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC73_0604	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FORC73_0605	COG0024	Methionine aminopeptidase
FORC73_0606	COG0052	Belongs to the universal ribosomal protein uS2 family
FORC73_0607	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FORC73_0608	COG0528	UMP kinase activity
FORC73_0609	COG0233	cytoplasmic translational termination
FORC73_0610	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FORC73_0611	COG0575	Belongs to the CDS family
FORC73_0612	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FORC73_0613	COG0750	zinc metalloprotease
FORC73_0615	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FORC73_0616	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC73_0617	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC73_0618	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC73_0619	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC73_0620	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FORC73_0621	COG0587	DNA-directed DNA polymerase activity
FORC73_0622	COG0825	malonyl-CoA metabolic process
FORC73_0623	COG0037	tRNA processing
FORC73_0625	COG3479	Phenolic acid decarboxylase
FORC73_0626	COG0347	Belongs to the P(II) protein family
FORC73_0628	COG0741	lytic transglycosylase activity
FORC73_0628	COG1388	LysM domain
FORC73_0629	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC73_0630	COG2226	methyltransferase
FORC73_0631	COG0328	RNA-DNA hybrid ribonuclease activity
FORC73_0632	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC73_0636	COG3220	belongs to the UPF0276 family
FORC73_0640	COG1294	oxidase, subunit
FORC73_0642	COG1960	acyl-CoA dehydrogenase activity
FORC73_0643	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC73_0644	COG0121	glutamine amidotransferase
FORC73_0645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC73_0646	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FORC73_0647	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FORC73_0648	COG3706	GGDEF domain
FORC73_0649	COG1187	pseudouridine synthase activity
FORC73_0650	COG2840	Smr protein MutS2
FORC73_0651	COG3735	TraB family
FORC73_0654	COG2217	Heavy metal translocating P-type atpase
FORC73_0654	COG2608	mercury ion transmembrane transporter activity
FORC73_0655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC73_0658	COG4774	siderophore transport
FORC73_0658	COG1629	transport
FORC73_0659	COG2375	cellular response to nickel ion
FORC73_0660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FORC73_0660	COG2226	methyltransferase
FORC73_0660	COG3433	isochorismatase activity
FORC73_0667	COG0835	chemotaxis
FORC73_0667	COG0784	Response regulator, receiver
FORC73_0668	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC73_0669	COG1815	bacterial-type flagellum-dependent cell motility
FORC73_0670	COG1558	bacterial-type flagellum-dependent cell motility
FORC73_0671	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FORC73_0672	COG1749	Flagellar hook protein flgE
FORC73_0673	COG4787	bacterial-type flagellum-dependent cell motility
FORC73_0674	COG4786	Flagellar basal body rod
FORC73_0675	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FORC73_0676	COG1706	bacterial-type flagellum-dependent cell motility
FORC73_0677	COG1705	Flagellar rod assembly protein muramidase FlgJ
FORC73_0677	COG3951	Flagellar rod assembly protein muramidase FlgJ
FORC73_0680	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC73_0681	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC73_0682	COG0012	GTP binding
FORC73_0683	COG0193	aminoacyl-tRNA hydrolase activity
FORC73_0684	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FORC73_0685	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FORC73_0686	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FORC73_0687	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FORC73_0688	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FORC73_0689	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC73_0690	COG3094	Invasion gene expression up-regulator, SirB
FORC73_0691	COG2912	Transglutaminase-like superfamily
FORC73_0692	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FORC73_0693	COG0737	Belongs to the 5'-nucleotidase family
FORC73_0694	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FORC73_0695	COG2233	PERMEase
FORC73_0699	COG1393	Belongs to the ArsC family
FORC73_0700	COG4783	chaperone-mediated protein folding
FORC73_0704	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC73_0706	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC73_0707	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FORC73_0709	COG1876	peptidase activity
FORC73_0710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC73_0711	COG1393	Belongs to the ArsC family
FORC73_0715	COG2837	iron assimilation
FORC73_0716	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC73_0717	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC73_0718	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC73_0719	COG1334	flagellar protein FlaG
FORC73_0720	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FORC73_0722	COG1516	flagellar protein fliS
FORC73_0723	COG2204	response regulator
FORC73_0724	COG4191	Histidine kinase
FORC73_0725	COG2204	response regulator
FORC73_0726	COG1677	Flagellar hook-basal body complex protein FliE
FORC73_0728	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC73_0729	COG1317	bacterial-type flagellum organization
FORC73_0733	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC73_0738	COG1987	bacterial-type flagellum assembly
FORC73_0739	COG1684	flagellar biosynthetic protein fliR
FORC73_0740	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FORC73_0742	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC73_0743	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FORC73_0744	COG2860	membrane
FORC73_0745	COG3101	peptidyl-lysine hydroxylation
FORC73_0748	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FORC73_0748	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC73_0749	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC73_0750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC73_0751	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC73_0752	COG0735	belongs to the Fur family
FORC73_0754	COG0583	DNA-binding transcription factor activity
FORC73_0756	COG1346	cytolysis
FORC73_0759	COG0596	Alpha beta hydrolase
FORC73_0760	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FORC73_0761	COG0033	Phosphoglucomutase
FORC73_0763	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC73_0764	COG0372	Belongs to the citrate synthase family
FORC73_0765	COG2009	succinate dehydrogenase
FORC73_0766	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FORC73_0767	COG1053	succinate dehydrogenase
FORC73_0769	COG0567	Dehydrogenase, E1 component
FORC73_0770	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC73_0771	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC73_0773	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC73_0774	COG1121	(ABC) transporter
FORC73_0775	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FORC73_0776	COG4977	sequence-specific DNA binding
FORC73_0778	COG1918	ferrous iron import across plasma membrane
FORC73_0782	COG0018	arginyl-trna synthetase
FORC73_0786	COG2062	phosphohistidine phosphatase, SixA
FORC73_0789	COG0455	bacterial-type flagellum organization
FORC73_0792	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FORC73_0793	COG0643	Histidine kinase
FORC73_0793	COG2198	Histidine kinase
FORC73_0794	COG2201	protein-glutamate methylesterase activity
FORC73_0795	COG1192	Involved in chromosome partitioning
FORC73_0797	COG0835	chemotaxis
FORC73_0799	COG4133	protoheme IX ABC transporter activity
FORC73_0800	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC73_0801	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC73_0803	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FORC73_0804	COG1138	Cytochrome C-type biogenesis protein
FORC73_0805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC73_0806	COG4235	cytochrome complex assembly
FORC73_0806	COG3088	subunit of a heme lyase
FORC73_0808	COG2853	Lipoprotein
FORC73_0812	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FORC73_0813	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC73_0814	COG0123	including yeast histone deacetylase and acetoin utilization protein
FORC73_0815	COG3083	sulfuric ester hydrolase activity
FORC73_0817	COG3081	Nucleoid-associated protein
FORC73_0819	COG1757	Na H antiporter
FORC73_0820	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC73_0821	COG2095	MarC family integral membrane protein
FORC73_0822	COG1012	belongs to the aldehyde dehydrogenase family
FORC73_0822	COG1454	alcohol dehydrogenase
FORC73_0824	COG0659	secondary active sulfate transmembrane transporter activity
FORC73_0825	COG1530	ribonuclease E activity
FORC73_0826	COG0564	pseudouridine synthase activity
FORC73_0827	COG0424	maF-like protein
FORC73_0828	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC73_0829	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FORC73_0830	COG0416	fatty acid biosynthetic process
FORC73_0831	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC73_0832	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FORC73_0833	COG1028	Short-chain dehydrogenase reductase Sdr
FORC73_0834	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC73_0835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC73_0836	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC73_0837	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC73_0838	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FORC73_0840	COG0084	hydrolase, TatD family'
FORC73_0841	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC73_0841	COG1263	PTS System
FORC73_0842	COG0733	neurotransmitter:sodium symporter activity
FORC73_0844	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC73_0846	COG1940	carbohydrate kinase activity
FORC73_0847	COG0835	chemotaxis
FORC73_0847	COG0784	Response regulator, receiver
FORC73_0850	COG2226	methyltransferase
FORC73_0852	COG0676	glucose-6-phosphate 1-epimerase activity
FORC73_0853	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC73_0854	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC73_0856	COG3139	Protein of unknown function (DUF1315)
FORC73_0857	COG0252	asparaginase activity
FORC73_0858	COG0616	signal peptide processing
FORC73_0859	COG1902	pentaerythritol trinitrate reductase activity
FORC73_0859	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC73_0860	COG0788	formyltetrahydrofolate deformylase activity
FORC73_0862	COG1199	ATP-dependent helicase activity
FORC73_0863	COG1214	PFAM Peptidase M22, glycoprotease
FORC73_0866	COG0596	Alpha beta hydrolase
FORC73_0867	COG0318	PFAM AMP-dependent synthetase and ligase
FORC73_0868	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FORC73_0871	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FORC73_0872	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FORC73_0873	COG0436	Aminotransferase
FORC73_0874	COG1169	isochorismate synthase
FORC73_0875	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FORC73_0876	COG0596	Alpha beta hydrolase
FORC73_0878	COG1441	menaquinone biosynthetic process
FORC73_0880	COG3135	benzoate transporter
FORC73_0881	COG1396	sequence-specific DNA binding
FORC73_0889	COG3015	lipoprotein NlpE involved in copper resistance
FORC73_0890	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FORC73_0891	COG2894	cell division
FORC73_0892	COG0850	regulation of cytokinetic process
FORC73_0893	COG3100	YcgL domain-containing protein
FORC73_0894	COG2951	lytic endotransglycosylase activity
FORC73_0896	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC73_0897	COG3005	denitrification pathway
FORC73_0898	COG0243	molybdopterin cofactor binding
FORC73_0901	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC73_0903	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FORC73_0909	COG4589	Belongs to the CDS family
FORC73_0911	COG5001	Diguanylate cyclase
FORC73_0911	COG3300	MHYT domain
FORC73_0913	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FORC73_0914	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC73_0915	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC73_0916	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC73_0918	COG4191	Histidine kinase
FORC73_0920	COG0544	peptidyl-prolyl cis-trans isomerase activity
FORC73_0922	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FORC73_0923	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FORC73_0924	COG0776	regulation of translation
FORC73_0925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC73_0926	COG1555	photosystem II stabilization
FORC73_0927	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FORC73_0928	COG0539	negative regulation of cytoplasmic translation
FORC73_0929	COG0776	regulation of translation
FORC73_0930	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FORC73_0931	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FORC73_0932	COG0284	orotidine-5'-phosphate decarboxylase activity
FORC73_0933	COG0601	transmembrane transport
FORC73_0934	COG4239	(ABC) transporter, permease
FORC73_0935	COG0747	negative chemotaxis
FORC73_0936	COG0444	Belongs to the ABC transporter superfamily
FORC73_0937	COG4608	Belongs to the ABC transporter superfamily
FORC73_0942	COG0583	DNA-binding transcription factor activity
FORC73_0944	COG0686	Belongs to the AlaDH PNT family
FORC73_0947	COG1674	ftsk spoiiie
FORC73_0948	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FORC73_0949	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC73_0950	COG2186	Transcriptional regulator
FORC73_0953	COG0537	adenosine 5'-monophosphoramidase activity
FORC73_0959	COG1252	NADH dehydrogenase
FORC73_0963	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC73_0965	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC73_0966	COG1136	(ABC) transporter
FORC73_0967	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC73_0969	COG2333	competence protein COMEC
FORC73_0969	COG0658	competence protein
FORC73_0970	COG1132	(ABC) transporter
FORC73_0971	COG1663	tetraacyldisaccharide 4'-kinase activity
FORC73_0973	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FORC73_0974	COG2719	SpoVR family
FORC73_0975	COG2718	Belongs to the UPF0229 family
FORC73_0976	COG2766	serine protein kinase
FORC73_0977	COG3013	Belongs to the UPF0304 family
FORC73_0979	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC73_0980	COG0840	transmembrane signaling receptor activity
FORC73_0982	COG1882	Formate acetyltransferase
FORC73_0986	COG4215	(ABC) transporter
FORC73_0987	COG4160	amino acid transport
FORC73_0988	COG0708	Exodeoxyribonuclease III
FORC73_0989	COG0840	transmembrane signaling receptor activity
FORC73_0991	COG3923	Primosomal replication protein n
FORC73_0992	COG0730	response to heat
FORC73_0993	COG1199	ATP-dependent helicase activity
FORC73_0994	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC73_0995	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FORC73_0997	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC73_0998	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC73_0999	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC73_1000	COG0215	cysteine-tRNA ligase activity
FORC73_1001	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FORC73_1002	COG0632	four-way junction helicase activity
FORC73_1003	COG2255	four-way junction helicase activity
FORC73_1004	COG1271	oxidase subunit
FORC73_1005	COG1294	oxidase, subunit
FORC73_1006	COG4890	Cyd operon protein YbgT
FORC73_1007	COG3790	cyd operon protein YbgE
FORC73_1008	COG0824	Thioesterase
FORC73_1009	COG0811	peptide transport
FORC73_1012	COG0823	Involved in the tonB-independent uptake of proteins
FORC73_1013	COG2885	chlorophyll binding
FORC73_1015	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FORC73_1019	COG0784	Response regulator, receiver
FORC73_1019	COG5002	protein histidine kinase activity
FORC73_1021	COG1012	belongs to the aldehyde dehydrogenase family
FORC73_1022	COG3335	DDE superfamily endonuclease
FORC73_1023	COG1012	belongs to the aldehyde dehydrogenase family
FORC73_1024	COG3284	Transcriptional regulator
FORC73_1025	COG4628	conserved protein (DUF2132)
FORC73_1027	COG0415	Belongs to the DNA photolyase family
FORC73_1038	COG2003	Belongs to the UPF0758 family
FORC73_1040	COG4409	exo-alpha-(2->6)-sialidase activity
FORC73_1041	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC73_1042	COG1940	carbohydrate kinase activity
FORC73_1043	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FORC73_1044	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC73_1045	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC73_1046	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC73_1047	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC73_1048	COG1737	Transcriptional regulator
FORC73_1049	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC73_1050	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC73_1052	COG5492	domain, Protein
FORC73_1052	COG4932	domain protein
FORC73_1056	COG2267	carboxylic ester hydrolase activity
FORC73_1080	COG4789	Type iii secretion
FORC73_1081	COG4792	protein secretion
FORC73_1087	COG3710	Transcriptional regulator
FORC73_1090	COG4790	Type iii secretion
FORC73_1107	COG0582	viral genome integration into host DNA
FORC73_1109	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC73_1111	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC73_1111	COG3008	intermembrane lipid transfer
FORC73_1112	COG2995	paraquat-inducible protein a
FORC73_1113	COG1309	transcriptional regulator
FORC73_1114	COG1012	belongs to the aldehyde dehydrogenase family
FORC73_1119	COG1960	acyl-CoA dehydrogenase activity
FORC73_1120	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC73_1121	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FORC73_1122	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FORC73_1123	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FORC73_1125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FORC73_1127	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC73_1128	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC73_1129	COG0297	glycogen (starch) synthase activity
FORC73_1133	COG3070	regulator of competence-specific genes
FORC73_1134	COG1609	Transcriptional regulator
FORC73_1135	COG3381	protein complex oligomerization
FORC73_1136	COG0745	RESPONSE REGULATOR receiver
FORC73_1137	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC73_1138	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC73_1139	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FORC73_1140	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FORC73_1141	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FORC73_1144	COG1032	radical SAM domain protein
FORC73_1146	COG0612	Peptidase, M16
FORC73_1149	COG0583	DNA-binding transcription factor activity
FORC73_1150	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FORC73_1152	COG2350	Protein conserved in bacteria
FORC73_1153	COG1607	acyl-coa hydrolase
FORC73_1154	COG2917	probably involved in intracellular septation
FORC73_1156	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC73_1157	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC73_1159	COG2116	formate transmembrane transporter activity
FORC73_1161	COG4459	periplasmic nitrate reductase
FORC73_1162	COG3005	denitrification pathway
FORC73_1163	COG0243	molybdopterin cofactor binding
FORC73_1166	COG1227	inorganic diphosphatase activity
FORC73_1169	COG4172	Belongs to the ABC transporter superfamily
FORC73_1171	COG4171	peptide transport system, permease
FORC73_1172	COG4168	peptide transport system, permease
FORC73_1174	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC73_1175	COG1842	Phage shock protein A
FORC73_1178	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC73_1181	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC73_1182	COG3385	transposase activity
FORC73_1184	COG2818	Glycosylase
FORC73_1185	COG0589	response to stress
FORC73_1187	COG0626	cystathionine gamma-synthase activity
FORC73_1189	COG0733	neurotransmitter:sodium symporter activity
FORC73_1190	COG0564	pseudouridine synthase activity
FORC73_1191	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC73_1192	COG4136	ATPase activity
FORC73_1193	COG4135	transport system, permease component
FORC73_1194	COG4134	Bacterial extracellular solute-binding protein
FORC73_1196	COG3313	Fe-S protein
FORC73_1198	COG0842	Transport permease protein
FORC73_1199	COG1131	(ABC) transporter
FORC73_1200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC73_1201	COG0814	amino acid
FORC73_1203	COG2239	Acts as a magnesium transporter
FORC73_1207	COG4934	collagen metabolic process
FORC73_1215	COG0840	transmembrane signaling receptor activity
FORC73_1218	COG2203	Gaf domain
FORC73_1218	COG4251	negative regulation of phosphorylation
FORC73_1218	COG3706	GGDEF domain
FORC73_1218	COG5001	Diguanylate cyclase
FORC73_1219	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FORC73_1220	COG5002	protein histidine kinase activity
FORC73_1223	COG1061	Type III restriction enzyme res subunit
FORC73_1224	COG1187	pseudouridine synthase activity
FORC73_1225	COG2814	Major facilitator Superfamily
FORC73_1227	COG0702	epimerase
FORC73_1228	COG0534	Mate efflux family protein
FORC73_1229	COG4181	ATPase activity
FORC73_1233	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC73_1235	COG1748	Saccharopine dehydrogenase
FORC73_1236	COG0019	diaminopimelate decarboxylase activity
FORC73_1238	COG1538	Outer membrane efflux protein
FORC73_1242	COG0583	DNA-binding transcription factor activity
FORC73_1244	COG1451	nucleotide metabolic process
FORC73_1247	COG3063	Type IV pilus biogenesis stability protein PilW
FORC73_1248	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FORC73_1252	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC73_1255	COG3290	protein histidine kinase activity
FORC73_1256	COG4565	transcriptional regulatory protein
FORC73_1258	COG0784	Response regulator, receiver
FORC73_1258	COG0835	chemotaxis
FORC73_1262	COG3706	GGDEF domain
FORC73_1262	COG0745	RESPONSE REGULATOR receiver
FORC73_1265	COG1085	galactose-1-phosphate uridylyltransferase
FORC73_1266	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FORC73_1267	COG2017	converts alpha-aldose to the beta-anomer
FORC73_1268	COG3706	GGDEF domain
FORC73_1269	COG1028	Short-chain dehydrogenase reductase Sdr
FORC73_1271	COG3527	Alpha-acetolactate decarboxylase
FORC73_1274	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC73_1284	COG1271	oxidase subunit
FORC73_1285	COG1294	oxidase, subunit
FORC73_1286	COG1136	(ABC) transporter
FORC73_1286	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC73_1287	COG1136	(ABC) transporter
FORC73_1287	COG0577	efflux transmembrane transporter activity
FORC73_1288	COG1136	(ABC) transporter
FORC73_1288	COG0577	efflux transmembrane transporter activity
FORC73_1293	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FORC73_1294	COG2723	6-phospho-beta-galactosidase activity
FORC73_1295	COG1609	Transcriptional regulator
FORC73_1296	COG0251	oxidation-reduction process
FORC73_1297	COG2731	YhcH YjgK YiaL family protein
FORC73_1298	COG0584	glycerophosphoryl diester phosphodiesterase
FORC73_1299	COG1349	DNA-binding transcription factor activity
FORC73_1300	COG3842	ATPase activity
FORC73_1301	COG0395	ABC-type sugar transport system, permease component
FORC73_1302	COG1175	transmembrane transport
FORC73_1305	COG0811	peptide transport
FORC73_1306	COG0811	peptide transport
FORC73_1307	COG0848	biopolymer transport protein
FORC73_1308	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FORC73_1310	COG1793	dna ligase
FORC73_1312	COG0534	Mate efflux family protein
FORC73_1316	COG0791	NLP P60 protein
FORC73_1317	COG0840	transmembrane signaling receptor activity
FORC73_1320	COG1940	carbohydrate kinase activity
FORC73_1322	COG0303	'Molybdopterin
FORC73_1323	COG0746	molybdenum cofactor guanylyltransferase activity
FORC73_1324	COG3842	ATPase activity
FORC73_1325	COG4662	Binding-protein-dependent transport system inner membrane component
FORC73_1327	COG2204	response regulator
FORC73_1328	COG3852	Histidine kinase
FORC73_1329	COG0488	(ABC) transporter
FORC73_1330	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC73_1336	COG3383	formate dehydrogenase (NAD+) activity
FORC73_1336	COG0243	molybdopterin cofactor binding
FORC73_1337	COG0437	4 iron, 4 sulfur cluster binding
FORC73_1340	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FORC73_1342	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC73_1345	COG2996	Protein conserved in bacteria
FORC73_1346	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC73_1346	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FORC73_1347	COG3008	intermembrane lipid transfer
FORC73_1348	COG2995	paraquat-inducible protein a
FORC73_1349	COG1132	(ABC) transporter
FORC73_1350	COG1956	GAF domain-containing protein
FORC73_1351	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FORC73_1354	COG0308	aminopeptidase N
FORC73_1356	COG0167	dihydroorotate dehydrogenase activity
FORC73_1358	COG0116	Belongs to the methyltransferase superfamily
FORC73_1358	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC73_1362	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC73_1363	COG1067	ATP-dependent peptidase activity
FORC73_1364	COG3120	sequence-specific DNA binding
FORC73_1370	COG3064	Membrane
FORC73_1370	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FORC73_1370	COG1073	alpha beta
FORC73_1371	COG2994	toxin metabolic process
FORC73_1376	COG2205	protein histidine kinase activity
FORC73_1376	COG0784	Response regulator, receiver
FORC73_1379	COG3278	Belongs to the heme-copper respiratory oxidase family
FORC73_1382	COG2010	Cytochrome c
FORC73_1384	COG2217	Heavy metal translocating P-type atpase
FORC73_1387	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC73_1388	COG0589	response to stress
FORC73_1389	COG0037	tRNA processing
FORC73_1393	COG3842	ATPase activity
FORC73_1394	COG1176	ABC-type spermidine putrescine transport system, permease component I
FORC73_1395	COG1177	transmembrane transport
FORC73_1396	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC73_1397	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC73_1400	COG1115	amino acid carrier protein
FORC73_1401	COG1280	lysine exporter protein (LysE YggA)
FORC73_1405	COG3501	Rhs element vgr protein
FORC73_1407	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC73_1409	COG2814	Major facilitator Superfamily
FORC73_1410	COG1566	PFAM secretion protein HlyD family protein
FORC73_1411	COG1538	Outer membrane efflux protein
FORC73_1413	COG0513	Belongs to the DEAD box helicase family
FORC73_1416	COG2076	Multidrug Resistance protein
FORC73_1417	COG0415	Belongs to the DNA photolyase family
FORC73_1418	COG0477	Major facilitator Superfamily
FORC73_1419	COG0583	DNA-binding transcription factor activity
FORC73_1421	COG0402	S-adenosylhomocysteine deaminase activity
FORC73_1422	COG0095	Lipoate-protein ligase
FORC73_1423	COG0443	Heat shock 70 kDa protein
FORC73_1425	COG1643	Atp-dependent helicase
FORC73_1432	COG0443	Heat shock 70 kDa protein
FORC73_1433	COG0443	Heat shock 70 kDa protein
FORC73_1434	COG3706	GGDEF domain
FORC73_1440	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FORC73_1441	COG0602	queuosine metabolic process
FORC73_1442	COG0561	phosphatase activity
FORC73_1444	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC73_1445	COG4597	amino acid ABC transporter
FORC73_1446	COG0765	amino acid transport
FORC73_1447	COG1126	abc transporter atp-binding protein
FORC73_1448	COG0670	Belongs to the BI1 family
FORC73_1449	COG2920	part of a sulfur-relay system
FORC73_1450	COG1254	Belongs to the acylphosphatase family
FORC73_1451	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC73_1452	COG3706	GGDEF domain
FORC73_1457	COG3437	response regulator, receiver
FORC73_1458	COG0625	glutathione transferase activity
FORC73_1460	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FORC73_1462	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC73_1468	COG0372	Belongs to the citrate synthase family
FORC73_1469	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FORC73_1470	COG2186	Transcriptional regulator
FORC73_1481	COG1129	ABC transporter
FORC73_1487	COG0745	RESPONSE REGULATOR receiver
FORC73_1488	COG2205	protein histidine kinase activity
FORC73_1489	COG3713	MltA-interacting MipA family protein
FORC73_1490	COG2990	Protein conserved in bacteria
FORC73_1492	COG2205	protein histidine kinase activity
FORC73_1493	COG0471	metal ion transport
FORC73_1495	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC73_1498	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC73_1499	COG3283	Transcriptional regulator of aromatic amino acids metabolism
FORC73_1500	COG3768	UPF0283 membrane protein
FORC73_1501	COG3106	COG3106 Predicted ATPase
FORC73_1504	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC73_1505	COG0494	nUDIX hydrolase
FORC73_1506	COG0814	amino acid
FORC73_1507	COG1760	l-serine dehydratase
FORC73_1508	COG0720	synthase
FORC73_1509	COG0840	transmembrane signaling receptor activity
FORC73_1510	COG0017	Asparaginyl-tRNA synthetase
FORC73_1511	COG0351	phosphomethylpyrimidine kinase
FORC73_1512	COG1448	Aminotransferase
FORC73_1515	COG0840	transmembrane signaling receptor activity
FORC73_1516	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FORC73_1517	COG2943	transferase activity, transferring hexosyl groups
FORC73_1518	COG1609	Transcriptional regulator
FORC73_1519	COG3394	polysaccharide catabolic process
FORC73_1520	COG1486	melibiose metabolic process
FORC73_1521	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC73_1523	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC73_1524	COG0726	polysaccharide deacetylase
FORC73_1525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC73_1526	COG1846	Transcriptional regulator
FORC73_1531	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC73_1534	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC73_1535	COG3108	Peptidase M15
FORC73_1541	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC73_1543	COG2814	Major facilitator Superfamily
FORC73_1547	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC73_1548	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC73_1549	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC73_1558	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FORC73_1559	COG4139	cobalamin transport
FORC73_1560	COG2988	succinylglutamate desuccinylase activity
FORC73_1563	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FORC73_1564	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FORC73_1565	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC73_1567	COG2925	Exonuclease
FORC73_1569	COG1346	cytolysis
FORC73_1570	COG0295	cytidine deaminase activity
FORC73_1572	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FORC73_1573	COG0500	methyltransferase
FORC73_1575	COG0776	regulation of translation
FORC73_1576	COG0072	phenylalanine-tRNA ligase activity
FORC73_1576	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC73_1577	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FORC73_1579	COG0745	RESPONSE REGULATOR receiver
FORC73_1579	COG3706	GGDEF domain
FORC73_1581	COG0322	excinuclease ABC activity
FORC73_1582	COG2197	response regulator
FORC73_1583	COG0417	DNA replication proofreading
FORC73_1584	COG5001	Diguanylate cyclase
FORC73_1586	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC73_1590	COG1228	amidohydrolase
FORC73_1591	COG0010	Belongs to the arginase family
FORC73_1592	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FORC73_1593	COG2986	histidine ammonia-lyase
FORC73_1597	COG0277	FAD linked oxidase domain protein
FORC73_1597	COG0247	lactate metabolic process
FORC73_1601	COG2885	chlorophyll binding
FORC73_1605	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FORC73_1607	COG0281	malic enzyme
FORC73_1609	COG2949	membrane
FORC73_1610	COG3706	GGDEF domain
FORC73_1611	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC73_1613	COG0492	ferredoxin-NADP+ reductase activity
FORC73_1614	COG4988	ABC transporter
FORC73_1615	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC73_1616	COG1187	pseudouridine synthase activity
FORC73_1617	COG0009	L-threonylcarbamoyladenylate synthase
FORC73_1618	COG0613	PHP domain protein
FORC73_1619	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC73_1620	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC73_1621	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORC73_1622	COG0134	indole-3-glycerol-phosphate synthase activity
FORC73_1622	COG0135	phosphoribosylanthranilate isomerase activity
FORC73_1623	COG0133	tryptophan synthase activity
FORC73_1624	COG0159	tryptophan synthase activity
FORC73_1626	COG1435	thymidine kinase activity
FORC73_1627	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FORC73_1628	COG1801	Protein of unknown function DUF72
FORC73_1629	COG4106	trans-aconitate 2-methyltransferase activity
FORC73_1630	COG0500	methyltransferase
FORC73_1631	COG0189	ligase activity
FORC73_1631	COG4067	protein conserved in archaea
FORC73_1634	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FORC73_1636	COG3852	Histidine kinase
FORC73_1639	COG3070	regulator of competence-specific genes
FORC73_1641	COG2431	L-lysine efflux transmembrane transporter activity
FORC73_1643	COG0076	glutamate decarboxylase activity
FORC73_1644	COG1737	Transcriptional regulator
FORC73_1645	COG1012	belongs to the aldehyde dehydrogenase family
FORC73_1645	COG1454	alcohol dehydrogenase
FORC73_1646	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC73_1648	COG0542	response to heat
FORC73_1649	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FORC73_1650	COG1278	Cold shock
FORC73_1652	COG1187	pseudouridine synthase activity
FORC73_1653	COG0140	phosphoribosyl-ATP diphosphatase activity
FORC73_1653	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FORC73_1654	COG0107	imidazoleglycerol-phosphate synthase activity
FORC73_1655	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FORC73_1656	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FORC73_1657	COG0131	Imidazoleglycerol-phosphate dehydratase
FORC73_1657	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC73_1658	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FORC73_1659	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FORC73_1660	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FORC73_1661	COG1757	Na H antiporter
FORC73_1662	COG2916	Histone family protein nucleoid-structuring protein H-NS
FORC73_1663	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC73_1664	COG0482	sulfurtransferase activity
FORC73_1665	COG2915	High frequency lysogenization protein hflD homolog
FORC73_1666	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC73_1668	COG2268	Band 7 protein
FORC73_1670	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FORC73_1673	COG0300	oxidoreductase activity
FORC73_1675	COG0501	Belongs to the peptidase M48B family
FORC73_1677	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FORC73_1678	COG2226	methyltransferase
FORC73_1679	COG0156	8-amino-7-oxononanoate synthase activity
FORC73_1680	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FORC73_1681	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC73_1682	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FORC73_1683	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC73_1684	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FORC73_1685	COG0653	protein targeting
FORC73_1686	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC73_1687	COG2199	diguanylate cyclase activity
FORC73_1687	COG2203	Gaf domain
FORC73_1689	COG4120	Belongs to the binding-protein-dependent transport system permease family
FORC73_1691	COG4628	conserved protein (DUF2132)
FORC73_1692	COG3092	negative regulation of chromosome organization
FORC73_1693	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC73_1694	COG0857	belongs to the CobB CobQ family
FORC73_1694	COG0280	phosphate acetyltransferase
FORC73_1695	COG0435	Glutathione S-transferase
FORC73_1696	COG4608	Belongs to the ABC transporter superfamily
FORC73_1697	COG0444	Belongs to the ABC transporter superfamily
FORC73_1698	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC73_1699	COG0601	transmembrane transport
FORC73_1703	COG2204	response regulator
FORC73_1704	COG3300	MHYT domain
FORC73_1704	COG5001	Diguanylate cyclase
FORC73_1705	COG4191	Histidine kinase
FORC73_1706	COG5002	protein histidine kinase activity
FORC73_1708	COG2201	protein-glutamate methylesterase activity
FORC73_1711	COG0009	L-threonylcarbamoyladenylate synthase
FORC73_1714	COG1881	PFAM PEBP family protein
FORC73_1722	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC73_1723	COG0640	Transcriptional regulator
FORC73_1724	COG3706	GGDEF domain
FORC73_1728	COG1946	Acyl-CoA thioesterase
FORC73_1729	COG1522	sequence-specific DNA binding
FORC73_1731	COG0616	signal peptide processing
FORC73_1732	COG1028	Short-chain dehydrogenase reductase Sdr
FORC73_1738	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FORC73_1739	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FORC73_1740	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FORC73_1741	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FORC73_1743	COG0745	RESPONSE REGULATOR receiver
FORC73_1744	COG0583	DNA-binding transcription factor activity
FORC73_1745	COG0778	Nitroreductase
FORC73_1746	COG1024	Enoyl-CoA hydratase
FORC73_1746	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC73_1747	COG0183	Belongs to the thiolase family
FORC73_1750	COG2067	long-chain fatty acid transport protein
FORC73_1752	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC73_1753	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FORC73_1754	COG2982	Protein involved in outer membrane biogenesis
FORC73_1755	COG0572	uridine kinase
FORC73_1757	COG0489	protein tyrosine kinase activity
FORC73_1758	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC73_1758	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC73_1760	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FORC73_1762	COG4109	DRTGG domain
FORC73_1763	COG2199	diguanylate cyclase activity
FORC73_1764	COG0314	molybdopterin synthase activity
FORC73_1765	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FORC73_1766	COG0315	cyclic pyranopterin monophosphate synthase activity
FORC73_1767	COG0521	Mo-molybdopterin cofactor biosynthetic process
FORC73_1768	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FORC73_1769	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC73_1770	COG2198	Histidine kinase
FORC73_1771	COG2204	response regulator
FORC73_1772	COG0556	nucleotide-excision repair
FORC73_1773	COG4657	Part of a membrane complex involved in electron transport
FORC73_1774	COG2878	Part of a membrane complex involved in electron transport
FORC73_1775	COG4656	Part of a membrane complex involved in electron transport
FORC73_1776	COG4658	electron transport chain
FORC73_1777	COG4659	FMN binding
FORC73_1778	COG4660	Part of a membrane complex involved in electron transport
FORC73_1779	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC73_1780	COG0346	lactoylglutathione lyase activity
FORC73_1783	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC73_1784	COG2056	Na+-H+ antiporter family
FORC73_1785	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC73_1786	COG1286	toxin biosynthetic process
FORC73_1787	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FORC73_1788	COG0285	dihydrofolate synthase activity
FORC73_1789	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FORC73_1790	COG0101	tRNA pseudouridine synthase activity
FORC73_1793	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC73_1794	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC73_1794	COG2190	(PTS) system
FORC73_1794	COG1263	PTS System
FORC73_1795	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC73_1796	COG1940	carbohydrate kinase activity
FORC73_1796	COG1846	Transcriptional regulator
FORC73_1797	COG4651	solute:proton antiporter activity
FORC73_1797	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC73_1798	COG0367	asparagine synthase
FORC73_1801	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FORC73_1802	COG0563	adenylate kinase activity
FORC73_1803	COG0326	Molecular chaperone. Has ATPase activity
FORC73_1804	COG3710	Transcriptional regulator
FORC73_1807	COG0622	Phosphoesterase
FORC73_1808	COG1090	epimerase
FORC73_1809	COG0300	oxidoreductase activity
FORC73_1810	COG3118	belongs to the thioredoxin family
FORC73_1811	COG0330	HflC and HflK could
FORC73_1812	COG1585	Membrane protein implicated in regulation of membrane protease activity
FORC73_1813	COG0789	Transcriptional regulator
FORC73_1816	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FORC73_1817	COG3115	cell septum assembly
FORC73_1818	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FORC73_1819	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC73_1820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC73_1822	COG2190	(PTS) system
FORC73_1823	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC73_1824	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC73_1825	COG1702	phosphate starvation-inducible protein PhoH
FORC73_1826	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FORC73_1827	COG4535	Mg2 and Co2 transporter CorC
FORC73_1828	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FORC73_1829	COG2888	peptidyl-tyrosine sulfation
FORC73_1830	COG0495	leucyl-tRNA aminoacylation
FORC73_1831	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FORC73_1832	COG1466	dna polymerase III delta subunit
FORC73_1833	COG0799	negative regulation of ribosome biogenesis
FORC73_1834	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FORC73_1835	COG0768	penicillin binding
FORC73_1836	COG0772	Belongs to the SEDS family
FORC73_1837	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC73_1838	COG1686	Belongs to the peptidase S11 family
FORC73_1839	COG2921	Belongs to the UPF0250 family
FORC73_1840	COG0321	lipoyl(octanoyl) transferase activity
FORC73_1841	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FORC73_1843	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC73_1848	COG1596	polysaccharide export
FORC73_1850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC73_1856	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FORC73_1858	COG0438	transferase activity, transferring glycosyl groups
FORC73_1860	COG1045	serine acetyltransferase
FORC73_1864	COG1045	serine acetyltransferase
FORC73_1865	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FORC73_1866	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FORC73_1867	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC73_1868	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC73_1870	COG0366	Alpha amylase catalytic
FORC73_1871	COG1263	PTS System
FORC73_1871	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC73_1872	COG1609	Transcriptional regulator
FORC73_1873	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC73_1874	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FORC73_1875	COG2011	ABC-type metal ion transport system permease component
FORC73_1876	COG1464	Belongs to the NlpA lipoprotein family
FORC73_1877	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FORC73_1879	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC73_1879	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC73_1881	COG3706	GGDEF domain
FORC73_1882	COG1611	Belongs to the LOG family
FORC73_1883	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC73_1884	COG2363	Small membrane protein
FORC73_1885	COG0583	DNA-binding transcription factor activity
FORC73_1887	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC73_1887	COG0301	tRNA thio-modification
FORC73_1889	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC73_1890	COG1722	exodeoxyribonuclease VII activity
FORC73_1891	COG0142	geranyltranstransferase activity
FORC73_1892	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FORC73_1893	COG0564	pseudouridine synthase activity
FORC73_1894	COG3098	single-species biofilm formation
FORC73_1898	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC73_1900	COG1671	Belongs to the UPF0178 family
FORC73_1901	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC73_1902	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FORC73_1903	COG0254	rRNA binding
FORC73_1904	COG1720	tRNA m6t6A37 methyltransferase activity
FORC73_1905	COG0442	prolyl-tRNA aminoacylation
FORC73_1909	COG0047	phosphoribosylformylglycinamidine synthase activity
FORC73_1909	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FORC73_1911	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FORC73_1912	COG0590	tRNA wobble adenosine to inosine editing
FORC73_1913	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC73_1919	COG0484	heat shock protein binding
FORC73_1920	COG0443	Heat shock 70 kDa protein
FORC73_1921	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FORC73_1922	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FORC73_1923	COG0497	DNA recombination
FORC73_1924	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC73_1925	COG2914	Belongs to the UPF0125 (RnfH) family
FORC73_1926	COG2867	negative regulation of translational initiation
FORC73_1927	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FORC73_1928	COG0582	viral genome integration into host DNA
FORC73_1936	COG0210	DNA helicase
FORC73_1940	COG3501	Rhs element vgr protein
FORC73_1952	COG2003	Belongs to the UPF0758 family
FORC73_1962	COG1061	Type III restriction enzyme res subunit
FORC73_1964	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FORC73_1965	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FORC73_1966	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC73_1968	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FORC73_1969	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
FORC73_1970	COG3051	citrate lyase alpha subunit
FORC73_1971	COG2301	Belongs to the HpcH HpaI aldolase family
FORC73_1972	COG3052	prosthetic group binding
FORC73_1973	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FORC73_1975	COG3630	sodium ion export across plasma membrane
FORC73_1976	COG5016	pyruvate
FORC73_1976	COG0511	ligase activity, forming carbon-carbon bonds
FORC73_1977	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FORC73_1979	COG4565	transcriptional regulatory protein
FORC73_1982	COG0583	DNA-binding transcription factor activity
FORC73_1983	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC73_1984	COG1115	amino acid carrier protein
FORC73_1985	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC73_1986	COG0583	DNA-binding transcription factor activity
FORC73_1988	COG1120	ATPase activity
FORC73_1989	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC73_1990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC73_1991	COG4592	Periplasmic binding protein
FORC73_1993	COG1028	Short-chain dehydrogenase reductase Sdr
FORC73_1994	COG1169	isochorismate synthase
FORC73_1995	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC73_1996	COG3433	isochorismatase activity
FORC73_1996	COG1535	isochorismatase
FORC73_1997	COG1584	GPR1 FUN34 yaaH family protein
FORC73_2024	COG0582	viral genome integration into host DNA
FORC73_2025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FORC73_2025	COG0519	Catalyzes the synthesis of GMP from XMP
FORC73_2026	COG0517	IMP dehydrogenase activity
FORC73_2026	COG0516	GMP reductase activity
FORC73_2027	COG1570	exodeoxyribonuclease VII activity
FORC73_2030	COG1160	GTP binding
FORC73_2031	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC73_2032	COG2976	Protein conserved in bacteria
FORC73_2033	COG0124	histidyl-tRNA synthetase
FORC73_2034	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FORC73_2037	COG0105	UTP biosynthetic process
FORC73_2038	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC73_2039	COG2975	iron-sulfur cluster assembly
FORC73_2040	COG0633	Ferredoxin
FORC73_2043	COG0316	Belongs to the HesB IscA family
FORC73_2044	COG0822	iron-sulfur transferase activity
FORC73_2046	COG1959	2 iron, 2 sulfur cluster binding
FORC73_2048	COG0483	inositol monophosphate 1-phosphatase activity
FORC73_2049	COG3385	transposase activity
FORC73_2050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC73_2051	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC73_2052	COG1862	Preprotein translocase
FORC73_2053	COG0343	queuine tRNA-ribosyltransferase activity
FORC73_2054	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FORC73_2055	COG0517	IMP dehydrogenase activity
FORC73_2057	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC73_2058	COG0583	DNA-binding transcription factor activity
FORC73_2059	COG0450	alkyl hydroperoxide reductase
FORC73_2060	COG3142	Participates in the control of copper homeostasis
FORC73_2063	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FORC73_2064	COG0581	inorganic phosphate transmembrane transporter activity
FORC73_2066	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FORC73_2067	COG0248	Ppx GppA phosphatase
FORC73_2069	COG5002	protein histidine kinase activity
FORC73_2070	COG0745	RESPONSE REGULATOR receiver
FORC73_2071	COG2974	May be involved in recombination
FORC73_2073	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC73_2076	COG0542	response to heat
FORC73_2078	COG0564	pseudouridine synthase activity
FORC73_2079	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC73_2080	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC73_2081	COG1605	Chorismate mutase
FORC73_2081	COG0077	Prephenate dehydratase
FORC73_2082	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC73_2083	COG5001	Diguanylate cyclase
FORC73_2084	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FORC73_2085	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FORC73_2087	COG0488	(ABC) transporter
FORC73_2089	COG1605	Chorismate mutase
FORC73_2089	COG0287	Prephenate dehydrogenase
FORC73_2090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC73_2091	COG3275	phosphorelay sensor kinase activity
FORC73_2092	COG3279	Response regulator of the LytR AlgR family
FORC73_2093	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC73_2094	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FORC73_2095	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORC73_2097	COG1966	Carbon starvation protein
FORC73_2098	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FORC73_2099	COG1047	Peptidyl-prolyl cis-trans
FORC73_2100	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FORC73_2101	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FORC73_2102	COG0196	riboflavin kinase activity
FORC73_2103	COG0728	peptidoglycan biosynthetic process
FORC73_2104	COG0268	Binds directly to 16S ribosomal RNA
FORC73_2105	COG0640	Transcriptional regulator
FORC73_2106	COG0583	DNA-binding transcription factor activity
FORC73_2107	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC73_2108	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FORC73_2109	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FORC73_2110	COG0730	response to heat
FORC73_2111	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
FORC73_2112	COG0494	nUDIX hydrolase
FORC73_2115	COG3066	DNA modification
FORC73_2116	COG0667	Aldo Keto reductase
FORC73_2118	COG2204	response regulator
FORC73_2119	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FORC73_2120	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FORC73_2122	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FORC73_2123	COG0513	Belongs to the DEAD box helicase family
FORC73_2124	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FORC73_2128	COG3153	acetyltransferase
FORC73_2135	COG4785	May be involved in cell division
FORC73_2136	COG1185	polyribonucleotide nucleotidyltransferase activity
FORC73_2137	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FORC73_2138	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FORC73_2139	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FORC73_2140	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FORC73_2141	COG0195	Participates in both transcription termination and antitermination
FORC73_2142	COG0779	Required for maturation of 30S ribosomal subunits
FORC73_2143	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC73_2144	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC73_2145	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC73_2146	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC73_2147	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FORC73_2148	COG1534	Rna-binding protein
FORC73_2149	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC73_2150	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC73_2151	COG2027	D-alanyl-D-alanine carboxypeptidase
FORC73_2152	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC73_2153	COG0739	heme binding
FORC73_2156	COG0316	Belongs to the HesB IscA family
FORC73_2157	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FORC73_2158	COG0628	permease
FORC73_2159	COG2813	Specifically methylates the guanine in position
FORC73_2161	COG0747	negative chemotaxis
FORC73_2162	COG0601	transmembrane transport
FORC73_2163	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC73_2164	COG0444	Belongs to the ABC transporter superfamily
FORC73_2165	COG4608	Belongs to the ABC transporter superfamily
FORC73_2167	COG2971	BadF BadG BcrA BcrD
FORC73_2171	COG3842	ATPase activity
FORC73_2173	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC73_2174	COG0004	ammonium transporteR
FORC73_2175	COG0347	Belongs to the P(II) protein family
FORC73_2176	COG3112	Uncharacterised protein family (UPF0231)
FORC73_2177	COG1049	propionate catabolic process, 2-methylcitrate cycle
FORC73_2178	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC73_2179	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC73_2180	COG1643	Atp-dependent helicase
FORC73_2183	COG1489	DNA binding
FORC73_2184	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC73_2185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC73_2187	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC73_2188	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FORC73_2189	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FORC73_2190	COG0842	Transport permease protein
FORC73_2191	COG1131	(ABC) transporter
FORC73_2192	COG0659	secondary active sulfate transmembrane transporter activity
FORC73_2193	COG0288	reversible hydration of carbon dioxide
FORC73_2196	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC73_2197	COG3107	peptidoglycan biosynthetic process
FORC73_2198	COG0792	nuclease activity
FORC73_2199	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC73_2200	COG2823	Periplasmic or secreted lipoprotein
FORC73_2201	COG2969	positive regulation of protein catabolic process
FORC73_2202	COG0625	glutathione transferase activity
FORC73_2203	COG2857	Cytochrome c1
FORC73_2206	COG0723	plastoquinol--plastocyanin reductase activity
FORC73_2207	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FORC73_2208	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FORC73_2209	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FORC73_2211	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC73_2212	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC73_2213	COG0335	large ribosomal subunit rRNA binding
FORC73_2214	COG0336	Belongs to the RNA methyltransferase TrmD family
FORC73_2215	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FORC73_2216	COG0228	four-way junction DNA binding
FORC73_2217	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC73_2218	COG4137	Cytochrome C assembly protein
FORC73_2219	COG4536	flavin adenine dinucleotide binding
FORC73_2220	COG1854	S-ribosylhomocysteine lyase activity
FORC73_2221	COG2918	glutathione biosynthetic process
FORC73_2222	COG0612	Peptidase, M16
FORC73_2223	COG1238	metal cluster binding
FORC73_2225	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FORC73_2226	COG0511	ligase activity, forming carbon-carbon bonds
FORC73_2226	COG5016	pyruvate
FORC73_2227	COG3630	sodium ion export across plasma membrane
FORC73_2228	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FORC73_2229	COG0527	aspartate kinase activity
FORC73_2230	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC73_2231	COG2137	regulation of response to DNA damage stimulus
FORC73_2232	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FORC73_2234	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FORC73_2235	COG4208	sulfate ABC transporter
FORC73_2239	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FORC73_2240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC73_2241	COG4942	peptidase
FORC73_2241	COG1388	LysM domain
FORC73_2242	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FORC73_2243	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FORC73_2244	COG0585	pseudouridine synthase activity
FORC73_2245	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FORC73_2246	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FORC73_2247	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FORC73_2248	COG1968	undecaprenyl-diphosphatase activity
FORC73_2249	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC73_2250	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC73_2252	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FORC73_2254	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FORC73_2256	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FORC73_2257	COG1610	YqeY-like protein
FORC73_2258	COG0358	DNA primase activity
FORC73_2259	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC73_2261	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC73_2262	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FORC73_2263	COG1349	DNA-binding transcription factor activity
FORC73_2264	COG0469	pyruvate kinase activity
FORC73_2266	COG0583	DNA-binding transcription factor activity
FORC73_2267	COG1279	arginine transmembrane transporter activity
FORC73_2268	COG0668	transmembrane transport
FORC73_2269	COG0191	fructose-bisphosphate aldolase activity
FORC73_2271	COG0126	phosphoglycerate kinase activity
FORC73_2272	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC73_2273	COG4771	TonB-dependent receptor
FORC73_2274	COG0583	DNA-binding transcription factor activity
FORC73_2275	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC73_2276	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FORC73_2277	COG3091	SprT-like family
FORC73_2278	COG2356	endonuclease I
FORC73_2279	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC73_2280	COG0189	ligase activity
FORC73_2281	COG1678	Uncharacterized ACR, COG1678
FORC73_2282	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FORC73_2283	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC73_2287	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC73_2288	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC73_2289	COG0762	integral membrane protein
FORC73_2290	COG1872	DUF167
FORC73_2292	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FORC73_2293	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC73_2294	COG2066	Belongs to the glutaminase family
FORC73_2295	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FORC73_2296	COG1194	a g-specific adenine glycosylase
FORC73_2297	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FORC73_2298	COG0741	lytic transglycosylase activity
FORC73_2300	COG0840	transmembrane signaling receptor activity
FORC73_2301	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FORC73_2302	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FORC73_2303	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC73_2304	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FORC73_2305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FORC73_2306	COG2967	ApaG domain
FORC73_2307	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC73_2309	COG3610	response to peptide
FORC73_2310	COG2966	Psort location CytoplasmicMembrane, score
FORC73_2311	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FORC73_2312	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FORC73_2313	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FORC73_2314	COG0142	geranyltranstransferase activity
FORC73_2315	COG0531	amino acid
FORC73_2317	COG0039	L-malate dehydrogenase activity
FORC73_2318	COG1438	arginine binding
FORC73_2321	COG0589	response to stress
FORC73_2325	COG2235	arginine
FORC73_2326	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC73_2327	COG1151	hydroxylamine reductase activity
FORC73_2328	COG0312	modulator of DNA gyrase
FORC73_2329	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC73_2330	COG3164	Protein of unknown function
FORC73_2331	COG1530	ribonuclease E activity
FORC73_2332	COG0424	maF-like protein
FORC73_2333	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FORC73_2334	COG1792	Involved in formation and maintenance of cell shape
FORC73_2335	COG1077	Cell shape determining protein MreB Mrl
FORC73_2344	COG1459	type II secretion system
FORC73_2345	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC73_2347	COG3267	Type II secretory pathway component ExeA
FORC73_2347	COG3409	Peptidoglycan-binding domain 1 protein
FORC73_2352	COG2199	diguanylate cyclase activity
FORC73_2352	COG2200	EAL domain
FORC73_2353	COG0629	single-stranded DNA binding
FORC73_2356	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC73_2358	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC73_2359	COG0527	aspartate kinase activity
FORC73_2360	COG1410	methionine synthase
FORC73_2360	COG0646	methionine synthase
FORC73_2362	COG0175	sulfate reduction
FORC73_2363	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC73_2364	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC73_2369	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC73_2370	COG0735	belongs to the Fur family
FORC73_2373	COG0166	Belongs to the GPI family
FORC73_2374	COG0432	Pfam Uncharacterised protein family UPF0047
FORC73_2375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC73_2376	COG0305	Participates in initiation and elongation during chromosome replication
FORC73_2378	COG0359	binds to the 23S rRNA
FORC73_2379	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FORC73_2380	COG2965	DNA replication, synthesis of RNA primer
FORC73_2381	COG0360	Binds together with S18 to 16S ribosomal RNA
FORC73_2383	COG2906	2 iron, 2 sulfur cluster binding
FORC73_2384	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC73_2385	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC73_2386	COG0049	tRNA binding
FORC73_2387	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FORC73_2389	COG2923	Belongs to the DsrF TusC family
FORC73_2390	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FORC73_2391	COG2964	Protein conserved in bacteria
FORC73_2392	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC73_2394	COG2900	Belongs to the SlyX family
FORC73_2395	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FORC73_2396	COG0330	HflC and HflK could
FORC73_2397	COG0330	HflC and HflK could
FORC73_2398	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC73_2399	COG1923	regulation of RNA biosynthetic process
FORC73_2400	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FORC73_2401	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FORC73_2402	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FORC73_2404	COG0802	atpase or kinase
FORC73_2405	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FORC73_2406	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FORC73_2407	COG1162	GTPase activity
FORC73_2408	COG0688	phosphatidylethanolamine metabolic process
FORC73_2409	COG0471	metal ion transport
FORC73_2411	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FORC73_2412	COG4942	peptidase
FORC73_2415	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FORC73_2416	COG2816	NAD+ diphosphatase activity
FORC73_2417	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FORC73_2418	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FORC73_2419	COG0085	RNA polymerase activity
FORC73_2420	COG0222	ribosome binding
FORC73_2421	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FORC73_2422	COG0081	regulation of translation
FORC73_2423	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FORC73_2424	COG0250	Participates in transcription elongation, termination and antitermination
FORC73_2425	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC73_2426	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC73_2427	COG1072	(Pantothenic acid kinase))
FORC73_2429	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FORC73_2431	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC73_2434	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FORC73_2436	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FORC73_2437	COG3118	belongs to the thioredoxin family
FORC73_2438	COG0513	Belongs to the DEAD box helicase family
FORC73_2439	COG0248	Ppx GppA phosphatase
FORC73_2440	COG2202	Pas domain
FORC73_2440	COG2205	protein histidine kinase activity
FORC73_2441	COG2814	Major facilitator Superfamily
FORC73_2444	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC73_2445	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FORC73_2446	COG0511	ligase activity, forming carbon-carbon bonds
FORC73_2447	COG0439	Biotin carboxylase
FORC73_2448	COG2264	protein methyltransferase activity
FORC73_2449	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC73_2450	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FORC73_2451	COG1609	Transcriptional regulator
FORC73_2454	COG0387	Pfam Sodium calcium exchanger
FORC73_2455	COG0129	dihydroxy-acid dehydratase activity
FORC73_2456	COG3265	gluconokinase activity
FORC73_2458	COG0800	Aldolase
FORC73_2461	COG0840	transmembrane signaling receptor activity
FORC73_2462	COG1982	Orn Lys Arg decarboxylase major
FORC73_2463	COG0531	amino acid
FORC73_2464	COG3710	Transcriptional regulator
FORC73_2465	COG0789	Transcriptional regulator
FORC73_2467	COG0138	bifunctional purine biosynthesis protein purh
FORC73_2468	COG0151	Belongs to the GarS family
FORC73_2470	COG0776	regulation of translation
FORC73_2471	COG1253	flavin adenine dinucleotide binding
FORC73_2473	COG3068	Protein conserved in bacteria
FORC73_2475	COG1573	uracil-dna glycosylase
FORC73_2476	COG0668	transmembrane transport
FORC73_2479	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FORC73_2482	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC73_2483	COG0438	transferase activity, transferring glycosyl groups
FORC73_2487	COG1216	Glycosyl transferase, family 2
FORC73_2493	COG1596	polysaccharide export
FORC73_2497	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC73_2507	COG1213	nucleotidyl transferase
FORC73_2509	COG0574	Belongs to the PEP-utilizing enzyme family
FORC73_2509	COG3848	Pyruvate phosphate dikinase
FORC73_2511	COG1216	Glycosyl transferase, family 2
FORC73_2512	COG1132	(ABC) transporter
FORC73_2515	COG2030	dehydratase
FORC73_2516	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC73_2518	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FORC73_2520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC73_2525	COG0859	PFAM glycosyl transferase family 9
FORC73_2527	COG1519	Transferase
FORC73_2533	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FORC73_2533	COG2755	lipolytic protein G-D-S-L family
FORC73_2534	COG3642	lipopolysaccharide core region biosynthetic process
FORC73_2535	COG0859	PFAM glycosyl transferase family 9
FORC73_2536	COG0463	Glycosyl transferase, family 2
FORC73_2537	COG0859	PFAM glycosyl transferase family 9
FORC73_2538	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FORC73_2539	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FORC73_2541	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FORC73_2542	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FORC73_2545	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC73_2546	COG1309	transcriptional regulator
FORC73_2547	COG1560	Kdo2-lipid A biosynthetic process
FORC73_2548	COG1560	Kdo2-lipid A biosynthetic process
FORC73_2549	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FORC73_2550	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FORC73_2551	COG1561	YicC-like family, N-terminal region
FORC73_2553	COG3385	transposase activity
FORC73_2554	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC73_2554	COG1263	PTS System
FORC73_2555	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORC73_2559	COG1120	ATPase activity
FORC73_2560	COG4774	siderophore transport
FORC73_2561	COG1132	(ABC) transporter
FORC73_2564	COG0514	ATP-dependent DNA helicase (RecQ)
FORC73_2565	COG2962	Rard protein
FORC73_2566	COG0405	Gamma-glutamyltransferase
FORC73_2568	COG1280	lysine exporter protein (LysE YggA)
FORC73_2569	COG0210	DNA helicase
FORC73_2571	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FORC73_2572	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC73_2596	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FORC73_2602	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC73_2604	COG0747	negative chemotaxis
FORC73_2609	COG1309	transcriptional regulator
FORC73_2610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC73_2611	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC73_2612	COG2960	long-chain fatty acid transporting porin activity
FORC73_2613	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FORC73_2614	COG0583	DNA-binding transcription factor activity
FORC73_2615	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FORC73_2616	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC73_2617	COG1739	Uncharacterized protein family UPF0029
FORC73_2618	COG1024	Enoyl-CoA hydratase
FORC73_2618	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC73_2619	COG0183	Belongs to the thiolase family
FORC73_2620	COG0583	DNA-binding transcription factor activity
FORC73_2621	COG2814	Major facilitator Superfamily
FORC73_2623	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FORC73_2624	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FORC73_2625	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FORC73_2626	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FORC73_2627	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FORC73_2628	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FORC73_2630	COG0356	it plays a direct role in the translocation of protons across the membrane
FORC73_2631	COG3312	ion transport
FORC73_2632	COG1475	DNA binding
FORC73_2633	COG1192	Involved in chromosome partitioning
FORC73_2634	COG0357	Ribosomal RNA small subunit methyltransferase G
FORC73_2635	COG0445	tRNA wobble uridine modification
FORC73_2636	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC73_2643	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FORC73_2652	COG4974	Belongs to the 'phage' integrase family
FORC73_2653	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FORC73_2654	COG0706	membrane insertase activity
FORC73_2655	COG0594	ribonuclease P activity
FORC73_2656	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FORC73_2657	COG1126	abc transporter atp-binding protein
FORC73_2666	COG0217	transcriptional regulatory protein
FORC73_2667	COG2084	Dehydrogenase
FORC73_2670	COG2909	trisaccharide binding
FORC73_2671	COG0058	SHG alpha-glucan phosphorylase activity
FORC73_2672	COG1640	4-alpha-glucanotransferase
FORC73_2673	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FORC73_2674	COG1943	Transposase
FORC73_2676	COG3501	Rhs element vgr protein
FORC73_2683	COG0471	metal ion transport
FORC73_2684	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FORC73_2689	COG0840	transmembrane signaling receptor activity
FORC73_2693	COG0671	phosphoesterase, PA-phosphatase related
FORC73_2694	COG3385	transposase activity
FORC73_2695	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FORC73_2697	COG1999	signal sequence binding
FORC73_2700	COG0786	glutamate:sodium symporter activity
FORC73_2704	COG3706	GGDEF domain
FORC73_2707	COG0813	purine-nucleoside phosphorylase activity
FORC73_2708	COG3272	Protein of unknown function (DUF1722)
FORC73_2710	COG0415	Belongs to the DNA photolyase family
FORC73_2711	COG1376	ErfK ybiS ycfS ynhG family protein
FORC73_2711	COG1388	LysM domain
FORC73_2714	COG0513	Belongs to the DEAD box helicase family
FORC73_2715	COG1770	oligopeptidase
FORC73_2720	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC73_2721	COG0573	inorganic phosphate transmembrane transporter activity
FORC73_2722	COG0581	inorganic phosphate transmembrane transporter activity
FORC73_2723	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FORC73_2728	COG0659	secondary active sulfate transmembrane transporter activity
FORC73_2730	COG0739	heme binding
FORC73_2731	COG3300	MHYT domain
FORC73_2731	COG5001	Diguanylate cyclase
FORC73_2732	COG0583	DNA-binding transcription factor activity
FORC73_2733	COG2814	Major facilitator Superfamily
FORC73_2737	COG1301	dicarboxylic acid transport
FORC73_2739	COG1342	Belongs to the UPF0251 family
FORC73_2745	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FORC73_2749	COG2771	luxR family
FORC73_2749	COG2200	EAL domain
FORC73_2750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC73_2752	COG0564	pseudouridine synthase activity
FORC73_2771	COG3501	Rhs element vgr protein
FORC73_2774	COG1869	D-ribose catabolic process
FORC73_2775	COG1129	ABC transporter
FORC73_2776	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC73_2777	COG1879	ABC-type sugar transport system periplasmic component
FORC73_2778	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC73_2779	COG1609	Transcriptional regulator
FORC73_2781	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FORC73_2783	COG0584	glycerophosphoryl diester phosphodiesterase
FORC73_2784	COG2271	Major facilitator Superfamily
FORC73_2791	COG0579	oxidoreductase
FORC73_2793	COG0242	peptide deformylase activity
FORC73_2796	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC73_2797	COG1609	Transcriptional regulator
FORC73_2798	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC73_2798	COG1017	nitric oxide dioxygenase activity
FORC73_2799	COG1320	monovalent cation:proton antiporter activity
FORC73_2800	COG2212	antiporter activity
FORC73_2804	COG2111	Na H antiporter
FORC73_2804	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC73_2807	COG0589	response to stress
FORC73_2808	COG0814	amino acid
FORC73_2809	COG3033	Beta-eliminating lyase
FORC73_2810	COG3530	Putative quorum-sensing-regulated virulence factor
FORC73_2812	COG5002	protein histidine kinase activity
FORC73_2812	COG5001	Diguanylate cyclase
FORC73_2813	COG1278	Cold shock
FORC73_2816	COG2304	oxidoreductase activity
FORC73_2821	COG0714	Associated with various cellular activities
FORC73_2822	COG0840	transmembrane signaling receptor activity
FORC73_2825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC73_2826	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC73_2827	COG3604	Transcriptional regulator
FORC73_2829	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC73_2829	COG1017	nitric oxide dioxygenase activity
FORC73_2830	COG1278	Cold shock
FORC73_2831	COG3036	rescue of stalled ribosome
FORC73_2836	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC73_2837	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FORC73_2837	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FORC73_2839	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC73_2841	COG0516	GMP reductase activity
FORC73_2843	COG0513	Belongs to the DEAD box helicase family
FORC73_2844	COG1943	Transposase
FORC73_2845	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC73_2846	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FORC73_2847	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FORC73_2848	COG3437	response regulator, receiver
FORC73_2848	COG0784	Response regulator, receiver
FORC73_2849	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC73_2849	COG4191	Histidine kinase
FORC73_2851	COG1757	Na H antiporter
FORC73_2852	COG2814	Major facilitator Superfamily
FORC73_2854	COG3706	GGDEF domain
FORC73_2856	COG3240	lipase activity
FORC73_2858	COG0840	transmembrane signaling receptor activity
FORC73_2859	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FORC73_2860	COG5380	lipid catabolic process
FORC73_2861	COG4412	M6 family metalloprotease domain protein
FORC73_2861	COG3291	Pkd domain containing protein
FORC73_2865	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC73_2866	COG4605	iron ion homeostasis
FORC73_2867	COG4604	ABC transporter, ATP-binding protein
FORC73_2868	COG2207	Transcriptional regulator
FORC73_2871	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC73_2876	COG3385	transposase activity
FORC73_2880	COG0745	RESPONSE REGULATOR receiver
FORC73_2882	COG3623	hexulose-6-phosphate isomerase
FORC73_2883	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FORC73_2884	COG0561	phosphatase activity
FORC73_2893	COG0745	RESPONSE REGULATOR receiver
FORC73_2894	COG5002	protein histidine kinase activity
FORC73_2906	COG1686	Belongs to the peptidase S11 family
FORC73_2910	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC73_2910	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC73_2911	COG0509	glycine decarboxylation via glycine cleavage system
FORC73_2912	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC73_2914	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FORC73_2915	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FORC73_2917	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FORC73_2918	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FORC73_2926	COG0454	-acetyltransferase
FORC73_2982	COG3549	Plasmid maintenance system killer
FORC73_2983	COG3093	addiction module antidote protein HigA
FORC73_2988	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC73_2990	COG2801	Transposase and inactivated derivatives
FORC73_2994	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC73_2998	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
FORC73_2999	COG2944	sequence-specific DNA binding
FORC73_3002	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC73_3009	COG2801	Transposase and inactivated derivatives
FORC73_3011	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC73_3022	COG1328	CTP reductase activity
FORC73_3023	COG0602	queuosine metabolic process
FORC73_3025	COG4067	protein conserved in archaea
FORC73_3025	COG0189	ligase activity
FORC73_3026	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC73_3026	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC73_3026	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FORC73_3027	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC73_3028	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC73_3028	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC73_3029	COG1609	Transcriptional regulator
FORC73_3030	COG0420	3'-5' exonuclease activity
FORC73_3031	COG0419	ATPase involved in DNA repair
FORC73_3032	COG2205	protein histidine kinase activity
FORC73_3032	COG0784	Response regulator, receiver
FORC73_3033	COG0156	8-amino-7-oxononanoate synthase activity
FORC73_3035	COG0038	chloride channel
FORC73_3036	COG0523	cobalamin synthesis protein
FORC73_3039	COG2200	EAL domain
FORC73_3041	COG3038	cytochrome b561
FORC73_3043	COG2116	formate transmembrane transporter activity
FORC73_3044	COG0583	DNA-binding transcription factor activity
FORC73_3046	COG3593	DNA synthesis involved in DNA repair
FORC73_3047	COG0737	Belongs to the 5'-nucleotidase family
FORC73_3050	COG1943	Transposase
FORC73_3051	COG2824	Alkylphosphonate utilization operon protein PhnA
FORC73_3057	COG3385	transposase activity
FORC73_3063	COG3706	GGDEF domain
FORC73_3067	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FORC73_3068	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FORC73_3070	COG0745	RESPONSE REGULATOR receiver
FORC73_3074	COG1943	Transposase
FORC73_3077	COG1943	Transposase
FORC73_3102	COG0023	Translation Initiation Factor
FORC73_3104	COG1181	Belongs to the D-alanine--D-alanine ligase family
FORC73_3106	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC73_3106	COG1042	CoA-binding domain protein
FORC73_3106	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC73_3107	COG0583	DNA-binding transcription factor activity
FORC73_3108	COG4771	TonB-dependent receptor
FORC73_3111	COG2050	protein possibly involved in aromatic compounds catabolism
FORC73_3116	COG0625	glutathione transferase activity
FORC73_3119	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FORC73_3120	COG4172	Belongs to the ABC transporter superfamily
FORC73_3121	COG4239	(ABC) transporter, permease
FORC73_3122	COG4174	ABC transporter (Permease)
FORC73_3123	COG4166	transmembrane transport
FORC73_3130	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC73_3131	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC73_3132	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC73_3134	COG3842	ATPase activity
FORC73_3136	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC73_3139	COG1175	transmembrane transport
FORC73_3140	COG3833	ABC-type maltose transport systems, permease component
FORC73_3144	COG1011	Hydrolase
FORC73_3147	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FORC73_3148	COG1970	mechanosensitive ion channel activity
FORC73_3149	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FORC73_3150	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC73_3150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC73_3151	COG0302	gtp cyclohydrolase
FORC73_3153	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC73_3155	COG2897	thiosulfate sulfurtransferase activity
FORC73_3157	COG2390	Transcriptional regulator
FORC73_3158	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC73_3159	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC73_3163	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FORC73_3165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC73_3170	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FORC73_3171	COG0583	DNA-binding transcription factor activity
FORC73_3172	COG0778	Nitroreductase
FORC73_3178	COG0640	Transcriptional regulator
FORC73_3180	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC73_3189	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC73_3189	COG1263	PTS System
FORC73_3191	COG1621	beta-fructofuranosidase activity
FORC73_3192	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC73_3193	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC73_3194	COG0840	transmembrane signaling receptor activity
FORC73_3196	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC73_3197	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC73_3200	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC73_3201	COG1760	l-serine dehydratase
FORC73_3202	COG2197	response regulator
FORC73_3203	COG3850	Histidine kinase
FORC73_3204	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC73_3206	COG0243	molybdopterin cofactor binding
FORC73_3209	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC73_3210	COG2197	response regulator
FORC73_3211	COG3851	Histidine kinase
FORC73_3212	COG2271	Major facilitator Superfamily
FORC73_3213	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC73_3215	COG3842	ATPase activity
FORC73_3216	COG3243	poly(R)-hydroxyalkanoic acid synthase
FORC73_3218	COG0183	Belongs to the thiolase family
FORC73_3220	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC73_3221	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC73_3224	COG3706	GGDEF domain
FORC73_3225	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC73_3227	COG1979	alcohol dehydrogenase
FORC73_3230	COG4191	Histidine kinase
FORC73_3231	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC73_3232	COG2271	Major facilitator Superfamily
FORC73_3233	COG0469	pyruvate kinase activity
FORC73_3234	COG2205	protein histidine kinase activity
FORC73_3234	COG2198	Histidine kinase
FORC73_3234	COG0784	Response regulator, receiver
FORC73_3235	COG1879	ABC-type sugar transport system periplasmic component
FORC73_3236	COG1803	Methylglyoxal synthase
FORC73_3237	COG1335	isochorismatase
FORC73_3238	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC73_3239	COG0210	DNA helicase
FORC73_3240	COG1289	transmembrane transporter activity
FORC73_3247	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FORC73_3248	COG4149	molybdate abc transporter
FORC73_3249	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC73_3250	COG1492	cobalamin metabolic process
FORC73_3257	COG5002	protein histidine kinase activity
FORC73_3257	COG0784	Response regulator, receiver
FORC73_3259	COG1879	ABC-type sugar transport system periplasmic component
FORC73_3261	COG2827	Endonuclease containing a URI domain
FORC73_3262	COG3132	Protein of unknown function, DUF480
FORC73_3267	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC73_3268	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC73_3269	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FORC73_3270	COG0247	lactate metabolic process
FORC73_3271	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC73_3272	COG3118	belongs to the thioredoxin family
FORC73_3276	COG4160	amino acid transport
FORC73_3277	COG4215	(ABC) transporter
FORC73_3278	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC73_3279	COG1126	abc transporter atp-binding protein
FORC73_3280	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FORC73_3282	COG0494	nUDIX hydrolase
FORC73_3283	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FORC73_3285	COG1309	transcriptional regulator
FORC73_3286	COG0513	Belongs to the DEAD box helicase family
FORC73_3287	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FORC73_3288	COG0814	amino acid
FORC73_3289	COG0840	transmembrane signaling receptor activity
FORC73_3290	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC73_3291	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FORC73_3293	COG1984	allophanate hydrolase subunit 2
FORC73_3296	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FORC73_3297	COG4181	ATPase activity
FORC73_3299	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC73_3300	COG5001	Diguanylate cyclase
FORC73_3300	COG1716	ATPase activity
FORC73_3302	COG0484	heat shock protein binding
FORC73_3305	COG0546	phosphoglycolate phosphatase activity
FORC73_3308	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC73_3310	COG0513	Belongs to the DEAD box helicase family
FORC73_3311	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FORC73_3313	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC73_3315	COG3046	protein related to deoxyribodipyrimidine photolyase
FORC73_3316	COG3397	chitin binding
FORC73_3317	COG3227	Zinc metalloprotease (Elastase)
FORC73_3320	COG1166	arginine decarboxylase activity
FORC73_3322	COG2239	Acts as a magnesium transporter
FORC73_3323	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC73_3324	COG0459	protein refolding
FORC73_3326	COG0527	aspartate kinase activity
FORC73_3327	COG0662	Cupin 2, conserved barrel domain protein
FORC73_3328	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FORC73_3329	COG0456	acetyltransferase
FORC73_3330	COG2154	pterin-4-alpha-carbinolamine dehydratase
FORC73_3331	COG3186	Phenylalanine-4-hydroxylase
FORC73_3332	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC73_3335	COG2264	protein methyltransferase activity
FORC73_3336	COG0583	DNA-binding transcription factor activity
FORC73_3339	COG2171	N-acyltransferase activity
FORC73_3340	COG1253	flavin adenine dinucleotide binding
FORC73_3341	COG1765	OsmC-like protein
FORC73_3346	COG0531	amino acid
FORC73_3347	COG3706	GGDEF domain
FORC73_3349	COG4989	oxidoreductase activity
FORC73_3350	COG0366	Alpha amylase catalytic
FORC73_3352	COG2067	long-chain fatty acid transport protein
FORC73_3353	COG2267	carboxylic ester hydrolase activity
FORC73_3354	COG3227	Zinc metalloprotease (Elastase)
FORC73_3355	COG3047	cAMP biosynthetic process
FORC73_3357	COG1686	Belongs to the peptidase S11 family
FORC73_3360	COG1271	oxidase subunit
FORC73_3364	COG3048	D-serine ammonia-lyase activity
FORC73_3365	COG0583	DNA-binding transcription factor activity
FORC73_3375	COG1063	alcohol dehydrogenase
FORC73_3376	COG0156	8-amino-7-oxononanoate synthase activity
FORC73_3377	COG2873	o-acetylhomoserine
FORC73_3379	COG0346	lactoylglutathione lyase activity
FORC73_3383	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC73_3384	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC73_3385	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC73_3386	COG0363	glucosamine-6-phosphate deaminase activity
FORC73_3387	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FORC73_3391	COG1929	Belongs to the glycerate kinase type-1 family
FORC73_3393	COG0748	coenzyme F420 binding
FORC73_3394	COG3721	Heme iron utilization protein
FORC73_3396	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FORC73_3397	COG0811	peptide transport
FORC73_3398	COG0848	biopolymer transport protein
FORC73_3399	COG4558	Periplasmic binding protein
FORC73_3400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC73_3401	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FORC73_3408	COG0633	Ferredoxin
FORC73_3408	COG3217	Mosc domain protein beta barrel domain protein
FORC73_3408	COG0633	Ferredoxin
FORC73_3408	COG3217	Mosc domain protein beta barrel domain protein
FORC73_3409	COG0418	dihydroorotase activity
FORC73_3411	COG3152	Membrane
FORC73_3413	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC73_3414	COG2354	Protein conserved in bacteria
FORC73_3415	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC73_3416	COG1278	Cold shock
FORC73_3422	COG1349	DNA-binding transcription factor activity
FORC73_3425	COG3833	ABC-type maltose transport systems, permease component
FORC73_3426	COG1175	transmembrane transport
FORC73_3428	COG3842	ATPase activity
FORC73_3429	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC73_3430	COG2801	Transposase and inactivated derivatives
FORC73_3432	COG0393	Putative heavy-metal-binding
FORC73_3433	COG2197	response regulator
FORC73_3434	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC73_3435	COG0835	chemotaxis
FORC73_3435	COG0784	Response regulator, receiver
FORC73_3436	COG1846	Transcriptional regulator
FORC73_3437	COG3706	GGDEF domain
FORC73_3444	COG0583	DNA-binding transcription factor activity
FORC73_3445	COG5001	Diguanylate cyclase
FORC73_3447	COG1741	Belongs to the pirin family
FORC73_3448	COG3123	guanosine phosphorylase activity
FORC73_3450	COG2211	Major facilitator Superfamily
FORC73_3453	COG1067	ATP-dependent peptidase activity
FORC73_3455	COG4172	Belongs to the ABC transporter superfamily
FORC73_3460	COG0583	DNA-binding transcription factor activity
FORC73_3461	COG1620	l-lactate permease
FORC73_3462	COG1304	FMN binding
FORC73_3464	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FORC73_3467	COG0840	transmembrane signaling receptor activity
FORC73_3469	COG0513	Belongs to the DEAD box helicase family
FORC73_3471	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FORC73_3473	COG1132	(ABC) transporter
FORC73_3475	COG1902	pentaerythritol trinitrate reductase activity
FORC73_3477	COG1280	lysine exporter protein (LysE YggA)
FORC73_3478	COG2207	Transcriptional regulator
FORC73_3482	COG1846	Transcriptional regulator
FORC73_3483	COG1764	response to oxidative stress
FORC73_3484	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC73_3485	COG0697	spore germination
FORC73_3487	COG0700	Nucleoside recognition
FORC73_3488	COG3366	ferrous iron transmembrane transporter activity
FORC73_3489	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC73_3491	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC73_3492	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC73_3493	COG2259	Doxx family
FORC73_3498	COG0363	glucosamine-6-phosphate deaminase activity
FORC73_3501	COG4580	involved in the transport of maltose and maltodextrins
FORC73_3504	COG0840	transmembrane signaling receptor activity
FORC73_3506	COG0840	transmembrane signaling receptor activity
FORC73_3508	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC73_3509	COG1126	abc transporter atp-binding protein
FORC73_3511	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC73_3512	COG4597	amino acid ABC transporter
FORC73_3513	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC73_3514	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC73_3514	COG2213	PTS system mannitol-specific
FORC73_3515	COG0246	Mannitol dehydrogenase
FORC73_3516	COG3722	fumarate hydratase activity
FORC73_3523	COG0697	spore germination
FORC73_3526	COG1335	isochorismatase
FORC73_3528	COG2910	NAD(P)H-binding
FORC73_3530	COG0840	transmembrane signaling receptor activity
FORC73_3531	COG4221	oxidoreductase activity
FORC73_3533	COG1901	pseudouridine methyltransferase
FORC73_3534	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC73_3536	COG0531	amino acid
FORC73_3537	COG1982	Orn Lys Arg decarboxylase major
FORC73_3542	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC73_3547	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FORC73_3549	COG0259	pyridoxamine-phosphate oxidase activity
FORC73_3554	COG3385	transposase activity
FORC73_3560	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FORC73_3561	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC73_3562	COG0840	transmembrane signaling receptor activity
FORC73_3563	COG0835	chemotaxis
FORC73_3564	COG0835	chemotaxis
FORC73_3565	COG0643	Histidine kinase
FORC73_3565	COG2198	Histidine kinase
FORC73_3569	COG0601	transmembrane transport
FORC73_3570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC73_3572	COG2194	sulfuric ester hydrolase activity
FORC73_3573	COG0642	Histidine kinase
FORC73_3574	COG0745	RESPONSE REGULATOR receiver
FORC73_3576	COG4221	oxidoreductase activity
FORC73_3580	COG1444	tRNA N-acetyltransferase activity
FORC73_3581	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine