locus-tag	class	description
AN947_00025	ENOG4105CDY	transcriptional regulatory protein
AN947_00030	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AN947_00035	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_00045	ENOG4108YYI	Protein of unknown function (DUF2810)
AN947_00050	ENOG41061ZR	Transcriptional regulator
AN947_00055	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
AN947_00060	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
AN947_00065	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AN947_00070	ENOG4108WC9	type VI secretion system effector, hcp1 family
AN947_00075	ENOG4105CS6	Rhs element vgr protein
AN947_00110	ENOG4105C8P	)-transporter
AN947_00115	ENOG4108Q67	UPF0319 protein
AN947_00140	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_00160	ENOG4105EYK	Phosphatidylglycerophosphatase B
AN947_00165	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
AN947_00190	ENOG4105D6U	Sodium Glutamate Symporter
AN947_00195	ENOG4105YE1	PilZ domain
AN947_00210	ENOG4105EFX	secretion protein, HlyD family
AN947_00215	ENOG4105KK7	inner membrane protein YiaW
AN947_00220	ENOG4106TD9	Diguanylate cyclase
AN947_00245	ENOG4107SEY	Conserved Protein
AN947_00255	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AN947_00260	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
AN947_00275	ENOG4105C1J	atp-dependent rna helicase
AN947_00310	ENOG4105CVA	phosphate
AN947_00315	ENOG4105C8U	phosphate abc transporter
AN947_00320	ENOG4105E2Z	phosphate ABC transporter (Permease
AN947_00325	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AN947_00330	ENOG4105BZU	Histidine kinase
AN947_00340	ENOG4105DWD	nucleoside recognition domain protein
AN947_00345	ENOG4105CHH	sulfate transporter
AN947_00355	ENOG4105DR5	peptidase
AN947_00360	ENOG4105BZU	Histidine kinase
AN947_00365	ENOG4105EQ2	LysR family Transcriptional regulator
AN947_00370	ENOG4105E5M	Multidrug resistance protein D
AN947_00375	ENOG4108Z4X	TRANSCRIPTIONal
AN947_00395	ENOG4105CK2	sodium dicarboxylate symporter
AN947_00440	ENOG4107RH7	Nicotinate phosphoribosyltransferase
AN947_00445	ENOG4105D9R	oxidoreductase
AN947_00455	ENOG4105BZU	Histidine kinase
AN947_00460	ENOG4107VXZ	Hydrolase
AN947_00470	ENOG4105D3G	Pseudouridine synthase
AN947_00530	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AN947_00535	ENOG4108JUB	Transcriptional regulator
AN947_00585	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
AN947_00590	ENOG4105C2J	ABC transporter
AN947_00595	ENOG4105CNN	ABC, transporter
AN947_00600	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AN947_00605	ENOG4108RVA	ribokinase
AN947_00610	ENOG4105ETE	Transcriptional regulator (LacI family
AN947_00615	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
AN947_00620	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
AN947_00625	ENOG4108I5U	Uridine phosphorylase
AN947_00635	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AN947_00640	ENOG4105CXY	transporter
AN947_00655	ENOG4105CQZ	Histidine kinase
AN947_00660	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AN947_00680	ENOG4105D5U	fad dependent oxidoreductase
AN947_00690	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AN947_00700	ENOG4105KJM	monovalent cation h antiporter subunit g
AN947_00705	ENOG41080TA	Multiple resistance and ph regulation protein f
AN947_00710	ENOG4105SC1	monovalent cation H antiporter subunit E
AN947_00715	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AN947_00720	ENOG4105MKQ	Monovalent cation H antiporter subunit C
AN947_00725	ENOG4105D65	subunit l
AN947_00740	ENOG4105CIC	tryptophan-specific transport protein
AN947_00755	ENOG4105VRT	cytoplasmic protein
AN947_00765	ENOG4105BZU	Histidine kinase
AN947_00770	ENOG4105VEQ	Cold shock protein
AN947_00805	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AN947_00810	ENOG41069D7	Methyl-accepting chemotaxis
AN947_00825	ENOG4105D9N	nucleoside
AN947_00830	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AN947_00840	ENOG4108JUA	Transcriptional regulator
AN947_00845	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AN947_00850	ENOG4105VEQ	Cold shock protein
AN947_00870	ENOG4108UNF	response regulator
AN947_00880	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AN947_00885	ENOG4105C5I	Dehydrogenase
AN947_00910	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AN947_00935	ENOG4108RS6	transposase
AN947_00940	ENOG4105C1J	atp-dependent rna helicase
AN947_00945	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
AN947_00950	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
AN947_00955	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AN947_00965	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AN947_00970	ENOG4105BZU	Histidine kinase
AN947_00980	ENOG4107S6Z	Na H antiporter
AN947_00985	ENOG4105E5M	Multidrug resistance protein D
AN947_01000	ENOG4105BZU	Histidine kinase
AN947_01005	ENOG4105KUU	lipolytic protein G-D-S-L family
AN947_01010	ENOG4106M3D	hemolysin
AN947_01015	ENOG4108N3W	hemolysin secretion protein
AN947_01020	ENOG4107IFA	Lipase (EC 3.1.1.3)
AN947_01030	ENOG4107G87	m6 family metalloprotease domain protein
AN947_01050	ENOG4105DHS	permease protein
AN947_01055	ENOG4105CM4	permease protein
AN947_01060	ENOG4108IPW	abc transporter atp-binding protein
AN947_01080	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AN947_01100	ENOG4105ETX	regulatoR
AN947_01110	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
AN947_01120	ENOG410667J	hydrolase
AN947_01150	ENOG4105DS1	cytochrome b561
AN947_01180	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AN947_01185	ENOG4105BZU	Histidine kinase
AN947_01210	ENOG4107QVI	Methyltransferase, type 11
AN947_01225	ENOG4105C2C	drug resistance transporter, Bcr CflA
AN947_01230	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_01240	ENOG4105DZ1	carboxypeptidase
AN947_01260	ENOG4108RS6	transposase
AN947_01265	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AN947_01270	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AN947_01275	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AN947_01285	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AN947_01295	ENOG4105F2I	Transposase
AN947_01320	ENOG4105C22	threonyL-tRNA synthetase
AN947_01325	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AN947_01330	ENOG41082NX	50s ribosomal protein l35
AN947_01335	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AN947_01375	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AN947_01450	ENOG4105D9U	N-acetyltransferase
AN947_01455	ENOG4105QNF	Outer membrane lipoprotein
AN947_01480	ENOG4105VXN	addiction module toxin, RelE StbE family
AN947_01495	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
AN947_01545	ENOG4105YGK	Pfam:UPF0157
AN947_01550	ENOG4105N14	lysine exporter protein LysE YggA
AN947_01720	ENOG41080ET	plasmid maintenance system killer protein
AN947_01725	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
AN947_01730	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
AN947_01750	ENOG4105QNF	Outer membrane lipoprotein
AN947_01845	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
AN947_01865	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
AN947_01870	ENOG4105W08	virulence gene repressor rsal
AN947_01885	ENOG4105F2I	Transposase
AN947_01905	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AN947_01990	ENOG4108RS6	transposase
AN947_02040	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AN947_02060	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
AN947_02065	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
AN947_02070	ENOG4105CGF	Aromatic amino acid aminotransferase
AN947_02080	ENOG4105DM4	PTS System
AN947_02085	ENOG4105DE4	1-phosphofructokinase
AN947_02090	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
AN947_02095	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
AN947_02100	ENOG4107RFY	SbcCD D subunit
AN947_02105	ENOG4105EYH	Exonuclease
AN947_02110	ENOG4108MGY	Histidine kinase
AN947_02115	ENOG4107KBT	8-Amino-7-oxononanoate synthase
AN947_02130	ENOG4105CKI	cobalamin synthesis protein
AN947_02140	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AN947_02145	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AN947_02155	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
AN947_02160	ENOG410607N	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity)
AN947_02165	ENOG4108RHM	integral membrane protein
AN947_02175	ENOG4105EPM	Diguanylate phosphodiesterase
AN947_02185	ENOG4105DS1	cytochrome b561
AN947_02195	ENOG4105TMB	Formate nitrite transporter
AN947_02200	ENOG4105DUM	transcriptional regulator, lysR family
AN947_02205	ENOG4108UQ5	membrane protein YcdZ
AN947_02215	ENOG4105CGH	5'-nucleotidase
AN947_02220	ENOG4105DU1	integral membrane protein, terc
AN947_02230	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AN947_02265	ENOG4105BZU	Histidine kinase
AN947_02275	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AN947_02285	ENOG4105BZU	Histidine kinase
AN947_02300	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AN947_02305	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AN947_02315	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AN947_02335	ENOG4105MQ5	zona occludens toxin
AN947_02360	ENOG4105VZ1	Replication Protein
AN947_02365	ENOG41067QW	Transcriptional regulator
AN947_02370	ENOG4108ZJT	translation initiation factor, Sui1
AN947_02380	ENOG4105CPF	Cell wall formation (By similarity)
AN947_02390	ENOG4105CD5	CoA-binding domain protein
AN947_02395	ENOG4105CWB	LysR family transcriptional Regulator
AN947_02415	ENOG4105KA0	thioesterase Superfamily protein
AN947_02435	ENOG4105CYM	Glutathione S-transferase
AN947_02450	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AN947_02455	ENOG4108JQ5	ABC transporter
AN947_02460	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
AN947_02465	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
AN947_02470	ENOG4105E43	Extracellular solute-binding protein, family 5
AN947_02495	ENOG4105DUX	Transporter
AN947_02510	ENOG4107RCV	ABC transporter, permease
AN947_02525	ENOG4107STF	Involved in phosphonate degradation (By similarity)
AN947_02530	ENOG4108JPW	Aminotransferase
AN947_02535	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
AN947_02540	ENOG4105NXH	GreA GreB family elongation factor
AN947_02545	ENOG4105PAD	Hydrolase
AN947_02555	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
AN947_02560	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AN947_02565	ENOG4105CKU	formyltetrahydrofolate synthetase
AN947_02570	ENOG4105E0X	reductase
AN947_02575	ENOG4105EUJ	GTP cyclohydrolase i
AN947_02580	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AN947_02585	ENOG4105D06	uba thif-type nad fad binding protein
AN947_02595	ENOG4105KHC	sulfurtransferase
AN947_02600	ENOG4107RHR	regulatoR
AN947_02610	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AN947_02615	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AN947_02640	ENOG4108M3J	Dehydrogenase
AN947_02655	ENOG4105RA2	Membrane
AN947_02665	ENOG4105ETT	transcriptional Regulator, LysR family
AN947_02670	ENOG41067V3	Antibiotic biosynthesis monooxygenase
AN947_02700	ENOG41080HT	Transcriptional regulator, arsr family
AN947_02710	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AN947_02755	ENOG4105C5Y	PTS System
AN947_02760	ENOG4105ETE	Transcriptional regulator (LacI family
AN947_02770	ENOG4105D7K	pfkb domain protein
AN947_02775	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AN947_02780	ENOG4108NVR	Methyl-accepting chemotaxis
AN947_02785	ENOG4108ZG0	Ompa motb domain protein
AN947_02790	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AN947_02795	ENOG4107VXZ	Hydrolase
AN947_02800	ENOG4108N3W	hemolysin secretion protein
AN947_02810	ENOG4105CEE	C4-dicarboxylate transporter
AN947_02815	ENOG4105EJQ	L-serine dehydratase
AN947_02840	ENOG4105ETE	Transcriptional regulator (LacI family
AN947_02845	ENOG4105WH1	Two component transcriptional regulator luxr family
AN947_02850	ENOG4105BZU	Histidine kinase
AN947_02865	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AN947_02885	ENOG4105DHT	Metal Dependent Phosphohydrolase
AN947_02890	ENOG4108KX4	response regulator
AN947_02895	ENOG4105BZU	Histidine kinase
AN947_02900	ENOG4105CXY	transporter
AN947_02905	ENOG4105C4Y	ABC transporter
AN947_02910	ENOG4107RCV	ABC transporter, permease
AN947_02915	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AN947_02920	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AN947_02930	ENOG4105CHU	acetyl-coa acetyltransferase
AN947_02940	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AN947_02945	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AN947_02960	ENOG4108UK2	deaminase
AN947_02990	ENOG4108ZXE	
AN947_03025	ENOG4105BZU	Histidine kinase
AN947_03030	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AN947_03040	ENOG4108I6A	alcohol dehydrogenase
AN947_03050	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
AN947_03060	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
AN947_03065	ENOG4105CXY	transporter
AN947_03070	ENOG4105CA9	Pyruvate kinase
AN947_03075	ENOG4105BZU	Histidine kinase
AN947_03080	ENOG4108SV3	Tmao reductase system periplasmic protein tort
AN947_03085	ENOG4108Z5K	methylglyoxal synthase
AN947_03090	ENOG4108RWI	nicotinamidase
AN947_03095	ENOG41080IJ	Diacylglycerol kinase
AN947_03110	ENOG41088T4	Helicase IV
AN947_03115	ENOG4105EM2	membrane
AN947_03145	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AN947_03150	ENOG4105E0C	molybdate abc transporter
AN947_03155	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AN947_03160	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AN947_03205	ENOG4105BZU	Histidine kinase
AN947_03210	ENOG4108QGH	periplasmic
AN947_03220	ENOG41082IR	Excinuclease ABC C subunit domain protein
AN947_03250	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AN947_03255	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AN947_03265	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
AN947_03270	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
AN947_03275	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AN947_03280	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AN947_03285	ENOG4105K63	Thioredoxin
AN947_03315	ENOG4105DUM	transcriptional regulator, lysR family
AN947_03320	ENOG4105DMR	ABC, transporter
AN947_03325	ENOG4105GBT	ABC transporter
AN947_03330	ENOG4106PMH	Extracellular solute-binding protein family 3
AN947_03335	ENOG4105E5Z	arginine transporter ATP-binding subunit
AN947_03345	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
AN947_03355	ENOG4108YZ4	nudix hydrolase
AN947_03360	ENOG4105C5W	Aldolase
AN947_03365	ENOG4106RE7	Cytochrome
AN947_03370	ENOG4108IG5	Transcriptional regulator
AN947_03375	ENOG4105C1J	atp-dependent rna helicase
AN947_03380	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
AN947_03390	ENOG4105E0U	tyrosine-specific transport protein
AN947_03395	ENOG4108N3W	hemolysin secretion protein
AN947_03400	ENOG4105CMR	udp-glucose 4-epimerase
AN947_03410	ENOG4105E7W	lamb ycsf family protein
AN947_03420	ENOG4107R7A	Allophanate hydrolase subunit 2
AN947_03430	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AN947_03435	ENOG4105CV6	ABC transporter, permease
AN947_03440	ENOG4108I0Y	(ABC) transporter
AN947_03450	ENOG4105RKW	reductase (By
AN947_03470	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AN947_03515	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AN947_03530	ENOG4107RE1	Inosine-guanosine kinase
AN947_03535	ENOG4105E0M	Sulfatase
AN947_03545	ENOG4105C1J	atp-dependent rna helicase
AN947_03550	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
AN947_03560	ENOG4105CVA	phosphate
AN947_03570	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
AN947_03575	ENOG4108M1A	Chitin-binding protein
AN947_03580	ENOG4105D4Y	metalloprotease
AN947_03590	ENOG4105CYW	agmatinase
AN947_03595	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AN947_03605	ENOG4105CJW	magnesium transporter
AN947_03610	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AN947_03625	ENOG4105CZK	Aspartate kinase
AN947_03630	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
AN947_03640	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
AN947_03645	ENOG41090A4	Pterin carbinolamine dehydratase
AN947_03650	ENOG4105MIR	Phenylalanine 4-monooxygenase
AN947_03655	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AN947_03670	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AN947_03675	ENOG4105EGI	Transcriptional regulator
AN947_03695	ENOG4105C37	(CBS) domain
AN947_03700	ENOG4108UKZ	OsmC family
AN947_03705	ENOG4107YWA	deoxycytidylate deaminase
AN947_03730	ENOG4105DVH	amino acid
AN947_03735	ENOG4106TD9	Diguanylate cyclase
AN947_03745	ENOG4108VAC	response regulator
AN947_03750	ENOG4108HRK	Histidine kinase
AN947_03765	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AN947_03770	ENOG4105C19	ABC transporter
AN947_03785	ENOG4107RGM	aldo keto reductase
AN947_03790	ENOG4107T9C	Alpha amylase catalytic region
AN947_03805	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AN947_03810	ENOG4108M0H	Extracellular lipase
AN947_03815	ENOG4107SDU	Methyl-accepting chemotaxis
AN947_03820	ENOG4105D4Y	metalloprotease
AN947_03830	ENOG4105EIF	outer membrane protein W
AN947_03840	ENOG41061WM	D-Alanyl-D-Alanine
AN947_03845	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AN947_03850	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AN947_03855	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AN947_03865	ENOG4105BZC	d-serine deaminase
AN947_03870	ENOG4105W8I	Transcriptional regulator
AN947_03915	ENOG4105CPQ	Dehydrogenase
AN947_03920	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AN947_03925	ENOG4105TMR	Functions as a holding molecular chaperone (holdase) which stabilizes unfolding intermediates and rapidly releases them in an active form once stress has abated. Plays an important role in protecting cells from severe heat shock and starvation, as well as in acid resistance of stationary-phase cells. It catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step (By similarity)
AN947_03930	ENOG4105TMR	Functions as a holding molecular chaperone (holdase) which stabilizes unfolding intermediates and rapidly releases them in an active form once stress has abated. Plays an important role in protecting cells from severe heat shock and starvation, as well as in acid resistance of stationary-phase cells. It catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step (By similarity)
AN947_03940	ENOG4105EXG	Transcriptional regulator
AN947_03945	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
AN947_03965	ENOG4107SSZ	Phosphatase
AN947_03970	ENOG4105DHT	Metal Dependent Phosphohydrolase
AN947_03975	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AN947_03980	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
AN947_03985	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AN947_04010	ENOG4105BZW	Glycerate kinase
AN947_04015	ENOG4105C6Z	Gluconate
AN947_04020	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
AN947_04025	ENOG4108NVR	Methyl-accepting chemotaxis
AN947_04030	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
AN947_04035	ENOG41090JE	Utilization Protein
AN947_04040	ENOG4105D4P	Coproporphyrinogen iii oxidase
AN947_04045	ENOG4105WQ5	TonB family
AN947_04050	ENOG41090AP	transport protein
AN947_04055	ENOG4106GFD	transport protein
AN947_04060	ENOG4107R4I	Periplasmic binding protein
AN947_04070	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AN947_04100	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_04105	ENOG4105QVC	MOSC domain-containing protein
AN947_04105	ENOG4105QVC	MOSC domain-containing protein
AN947_04110	ENOG4105EKE	dihydroorotase
AN947_04120	ENOG4105KAF	membrAne
AN947_04130	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
AN947_04135	ENOG4105CKW	Inner membrane protein yedI
AN947_04140	ENOG4108ESY	Metal dependent phosphohydrolase
AN947_04145	ENOG4105VEQ	Cold shock protein
AN947_04170	ENOG4105BZU	Histidine kinase
AN947_04175	ENOG4105E98	transcriptional regulator DeoR family
AN947_04190	ENOG4105EG2	ABC transporter, permease
AN947_04195	ENOG4105D56	permease protein
AN947_04200	ENOG4107FKK	extracellular solute-binding protein family 1
AN947_04205	ENOG4108IJ9	(ABC) transporter
AN947_04210	ENOG4108HK0	-acetyltransferase
AN947_04225	ENOG4105K8R	UPF0145 protein
AN947_04230	ENOG41086KC	Transcriptional regulator
AN947_04235	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
AN947_04240	ENOG4107R88	Chemotaxis protein (CheV)
AN947_04245	ENOG4105K56	Transcriptional regulator
AN947_04250	ENOG4106TD9	Diguanylate cyclase
AN947_04270	ENOG4105BZU	Histidine kinase
AN947_04290	ENOG4105ETT	transcriptional Regulator, LysR family
AN947_04295	ENOG4108K0B	C-di-gmp phosphodiesterase
AN947_04305	ENOG4105EUB	pirin domain protein
AN947_04310	ENOG4105NBK	UPF0345 protein
AN947_04320	ENOG4105E5W	Transporter
AN947_04330	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_04335	ENOG4105DAN	ATP-dependent protease
AN947_04345	ENOG4108JQ5	ABC transporter
AN947_04355	ENOG4107SDU	Methyl-accepting chemotaxis
AN947_04370	ENOG4105CC0	LysR family Transcriptional regulator
AN947_04375	ENOG4105DAA	L-lactate
AN947_04380	ENOG4105DMF	Dehydrogenase
AN947_04390	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AN947_04400	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AN947_04410	ENOG4105C1J	atp-dependent rna helicase
AN947_04415	ENOG4105CR8	Transcriptional regulator
AN947_04425	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AN947_04435	ENOG4105BZ1	(ABC) transporter
AN947_04445	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AN947_04480	ENOG4105K56	Transcriptional regulator
AN947_04485	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AN947_04495	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AN947_04500	ENOG4105VW4	glutaredoxin 3
AN947_04505	ENOG4108P2H	Inner membrane protein YjiG
AN947_04510	ENOG41074DU	domain protein
AN947_04525	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AN947_04530	ENOG4105D03	DNA-3-methyladenine glycosylase II
AN947_04535	ENOG4108VGI	doxx family
AN947_04560	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AN947_04570	ENOG4107W52	maltose operon periplasmic protein
AN947_04575	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
AN947_04590	ENOG4108N3W	hemolysin secretion protein
AN947_04605	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_04615	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AN947_04620	ENOG4105CDA	abc transporter atp-binding protein
AN947_04630	ENOG4106TNF	Periplasmic binding protein
AN947_04635	ENOG4105EZ7	amino acid ABC transporter
AN947_04640	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
AN947_04650	ENOG4105DR5	peptidase
AN947_04665	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
AN947_04670	ENOG4105E61	Mannitol repressor protein
AN947_04675	ENOG4105EP9	oxidoreductase
AN947_04705	ENOG4108RYK	Nad-dependent epimerase dehydratase
AN947_04710	ENOG4105JQN	Transcriptional regulator
AN947_04715	ENOG41069D7	Methyl-accepting chemotaxis
AN947_04720	ENOG4105EMU	Dehydrogenase
AN947_04725	ENOG4105JQN	Transcriptional regulator
AN947_04735	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AN947_04740	ENOG4105D5Q	Arginine ornithine antiporter
AN947_04745	ENOG4105CXN	decarboxylase
AN947_04755	ENOG4107RGH	Aldehyde dehydrogenase
AN947_04760	ENOG4105EW9	transcriptional regulator AsnC family
AN947_04765	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_04775	ENOG4105CK7	Sodium proline symporter
AN947_04785	ENOG4105C26	Dehydrogenase
AN947_04800	ENOG4105E6M	Sulphatase-modifying factor protein
AN947_04810	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AN947_04815	ENOG4107QZV	Type I secretion membrane fusion protein
AN947_04830	ENOG4108JJA	ABC, transporter
AN947_04840	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AN947_04850	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_04855	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AN947_04860	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AN947_04865	ENOG4105BZU	Histidine kinase
AN947_04870	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_04875	ENOG4108V3W	Chemotaxis protein, CheW
AN947_04880	ENOG4108V3W	Chemotaxis protein, CheW
AN947_04885	ENOG4105CBS	Chea signal transduction histidine kinase
AN947_04890	ENOG4108VYJ	response regulator receiver protein
AN947_04905	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AN947_04910	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AN947_04915	ENOG4108JQ6	ABC transporter
AN947_04920	ENOG4105DIJ	Phosphoethanolamine transferase
AN947_04925	ENOG4105DHQ	Histidine kinase
AN947_04930	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AN947_04960	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
AN947_04965	ENOG4107RUE	extracellular solute-binding protein family 1
AN947_04970	ENOG4106RMF	ParB family
AN947_04985	ENOG4105QTB	Flavodoxin
AN947_04990	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AN947_05000	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AN947_05005	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AN947_05020	ENOG4105E5Q	amino acid AbC transporter
AN947_05025	ENOG4105EAB	amino acid AbC transporter
AN947_05030	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AN947_05035	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AN947_05040	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AN947_05045	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AN947_05060	ENOG4108ZNX	Heat shock protein
AN947_05065	ENOG4105JKW	Valine--pyruvate aminotransferase
AN947_05070	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AN947_05075	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
AN947_05090	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AN947_05100	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
AN947_05105	ENOG4105C7B	Threonine dehydratase
AN947_05110	ENOG4105C01	Dihydroxy-acid dehydratase
AN947_05115	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AN947_05130	ENOG4105C0P	Mg chelatase subunit ChlI
AN947_05135	ENOG4106HNH	Acyl-transferase
AN947_05140	ENOG4108Z33	Thiol disulfide Interchange Protein
AN947_05155	ENOG4105PC1	Conserved Protein
AN947_05165	ENOG4108N23	SpoOM-related protein
AN947_05170	ENOG4108UT2	hemolysin iii
AN947_05180	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AN947_05185	ENOG4105C1A	potassium transporter peripheral membrane
AN947_05190	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AN947_05195	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AN947_05200	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AN947_05205	ENOG4108WZM	domain protein
AN947_05210	ENOG4105C79	DNA protecting protein DprA
AN947_05215	ENOG4108RPN	Protein smg homolog
AN947_05220	ENOG4108WI1	Dna topoisomerase
AN947_05225	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AN947_05230	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AN947_05235	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AN947_05240	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AN947_05245	ENOG4105E2X	shikimate dehydrogenase
AN947_05255	ENOG4108Z0R	Transferase
AN947_05295	ENOG4105WMR	Protein CrcB homolog
AN947_05300	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AN947_05310	ENOG4105D06	uba thif-type nad fad binding protein
AN947_05315	ENOG4105WHD	thiamine biosynthesis protein ThiS
AN947_05320	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AN947_05325	ENOG4105D41	biosynthesis protein thiH
AN947_05330	ENOG4105DC7	peptidase M24
AN947_05330	ENOG4105DC7	peptidase M24
AN947_05340	ENOG4105CNH	Multidrug resistance protein MdtL
AN947_05350	ENOG4108VVK	transcriptional Regulator, AsnC
AN947_05355	ENOG4105BZU	Histidine kinase
AN947_05360	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
AN947_05370	ENOG4105EMK	carboxylate amino acid amine transporter
AN947_05375	ENOG4108M6U	Universal stress protein A
AN947_05385	ENOG41090A1	ferritin
AN947_05390	ENOG4108V6B	universal stress protein B
AN947_05395	ENOG4105CBX	hi0933 family
AN947_05405	ENOG4105CGY	Dna recombination protein
AN947_05410	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AN947_05415	ENOG4105JC1	sterol-binding domain protein
AN947_05420	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AN947_05425	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AN947_05430	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AN947_05435	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AN947_05440	ENOG4105CA0	peroxidase
AN947_05445	ENOG4107R73	Mate efflux family protein
AN947_05455	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AN947_05460	ENOG4105E55	glycerol-3-phosphate acyltransferase
AN947_05465	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AN947_05470	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
AN947_05480	ENOG4105X6C	Flagellar basal body-associated protein FliL
AN947_05485	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_05495	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AN947_05510	ENOG4105D52	delta-aminolevulinic acid dehydratase
AN947_05520	ENOG4105C2M	dna polymerase I
AN947_05525	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AN947_05540	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
AN947_05545	ENOG4105XCT	Protein of unknown function (DUF2489)
AN947_05550	ENOG4105D4P	Coproporphyrinogen iii oxidase
AN947_05555	ENOG410601J	HemY protein
AN947_05560	ENOG4105ECF	c-methyltransferase
AN947_05565	ENOG41076E6	Uroporphyrinogen-III Synthase
AN947_05570	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AN947_05580	ENOG4107T0K	Adenylate cyclase
AN947_05585	ENOG4105XQ6	frataxin-like protein
AN947_05595	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AN947_05600	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AN947_05605	ENOG4105CT0	Protein of unknown function, DUF484
AN947_05610	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AN947_05615	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
AN947_05620	ENOG4105BZU	Histidine kinase
AN947_05640	ENOG4105DQF	Hydrolase
AN947_05645	ENOG4108EUD	Lysophospholipase
AN947_05650	ENOG410829K	Lysine exporter protein (Lyse ygga)
AN947_05655	ENOG4105D58	Diguanylate phosphodiesterase
AN947_05660	ENOG4108RMU	ferritin dps family protein
AN947_05695	ENOG4106H78	methyltransferase
AN947_05705	ENOG4105CAK	Cell division ATP-binding protein ftsE
AN947_05710	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AN947_05715	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AN947_05735	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
AN947_05745	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AN947_05750	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AN947_05785	ENOG4105EMY	transcriptional regulator
AN947_05790	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AN947_05795	ENOG4105W0Z	cytoplasmic protein
AN947_05800	ENOG4105BZS	acriflavin resistance protein
AN947_05805	ENOG410624X	efflux transporter, rnd family, mfp subunit
AN947_05810	ENOG4105Y7M	Transcriptional regulator, TetR family
AN947_05815	ENOG4105C4R	Atp-dependent dna helicase
AN947_05820	ENOG4105MPD	Cytochrome
AN947_05865	ENOG4105DEF	Extracellular solute-binding protein, family 5
AN947_05870	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AN947_05875	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AN947_05885	ENOG4108UK2	deaminase
AN947_05915	ENOG4108ZXE	
AN947_05950	ENOG4105DC8	reductase
AN947_05955	ENOG4105D6S	protein involved in catabolism of external DNA
AN947_05960	ENOG4105DGW	oligopeptidase A
AN947_05965	ENOG4105C4R	Atp-dependent dna helicase
AN947_05975	ENOG4108DMH	HTH_ARAC
AN947_05985	ENOG4105FR1	rard protein
AN947_05990	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AN947_06005	ENOG4105BZ1	(ABC) transporter
AN947_06010	ENOG4105E0K	tonB-dependent siderophore receptor
AN947_06015	ENOG4105E0A	ABC, transporter
AN947_06020	ENOG4105J76	Periplasmic binding protein
AN947_06025	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
AN947_06030	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
AN947_06040	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AN947_06045	ENOG4105C5Y	PTS System
AN947_06055	ENOG4105DSJ	YicC domain protein
AN947_06060	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AN947_06065	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AN947_06070	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
AN947_06075	ENOG4105D1S	lipid A biosynthesis
AN947_06080	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
AN947_06085	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AN947_06090	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_06100	ENOG4105KDC	50s ribosomal protein l28
AN947_06105	ENOG4105W0E	50S ribosomal protein L33
AN947_06115	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AN947_06120	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AN947_06125	ENOG4105M5K	heptosyltransferase
AN947_06130	ENOG4106WTF	Glycosyl transferase, family 2
AN947_06135	ENOG4105DKP	glycosyl transferase, family 9
AN947_06140	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
AN947_06170	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AN947_06175	ENOG4108ST3	glycosyltransferase
AN947_06185	ENOG4105XA0	heptosyltransferase ii
AN947_06200	ENOG4107T94	Endo-14-beta-xylanase
AN947_06205	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
AN947_06215	ENOG4105E3R	(LipO)protein
AN947_06225	ENOG4108MDC	(LipO)protein
AN947_06250	ENOG410600T	transposase
AN947_06270	ENOG4105FGF	GDP-mannose mannosyl hydrolase
AN947_06295	ENOG4105K64	Glycosyl transferase, family 2
AN947_06300	ENOG4105K64	Glycosyl transferase, family 2
AN947_06310	ENOG4105CAQ	asparagine synthetase
AN947_06315	ENOG4105CGN	Glycosyl transferase (Group 1
AN947_06320	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AN947_06335	ENOG4105D3Q	Sugar transferase
AN947_06355	ENOG4105CY0	Metallo-Beta-Lactamase
AN947_06370	ENOG4105CUY	Mechanosensitive ion channel
AN947_06375	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
AN947_06380	ENOG4105R2J	Conserved Protein
AN947_06395	ENOG4105K70	DNA-binding protein
AN947_06405	ENOG4105C12	Phosphoribosylglycinamide synthetase
AN947_06410	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AN947_06420	ENOG4105W1Y	Transcriptional regulator
AN947_06425	ENOG4108M3R	transcriptional activator CadC
AN947_06430	ENOG4105D5Q	Arginine ornithine antiporter
AN947_06435	ENOG4105CXN	decarboxylase
AN947_06440	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_06455	ENOG4105E0K	tonB-dependent siderophore receptor
AN947_06460	ENOG4108UHU	Aldolase
AN947_06465	ENOG4105C6Z	Gluconate
AN947_06475	ENOG4105C01	Dihydroxy-acid dehydratase
AN947_06480	ENOG4105DIQ	Transcriptional regulator
AN947_06485	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AN947_06490	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AN947_06495	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AN947_06500	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AN947_06505	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AN947_06510	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AN947_06515	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AN947_06535	ENOG4105D8G	Major Facilitator superfamily
AN947_06540	ENOG4105BZU	Histidine kinase
AN947_06545	ENOG4105C9X	ppx gppa phosphatase
AN947_06550	ENOG4105C1J	atp-dependent rna helicase
AN947_06555	ENOG4105K63	Thioredoxin
AN947_06570	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AN947_06580	ENOG4107QK7	reductase
AN947_06615	ENOG4105JIM	Phosphatidylserine synthase
AN947_06630	ENOG4105D4A	Cell wall formation (By similarity)
AN947_06635	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AN947_06640	ENOG4105CS9	pantothenic acid kinase
AN947_06665	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AN947_06670	ENOG4105PM1	preprotein translocase subunit SecE
AN947_06675	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AN947_06680	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AN947_06685	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AN947_06690	ENOG4108VZM	50s ribosomal protein L10
AN947_06695	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AN947_06700	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AN947_06705	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AN947_06710	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
AN947_06715	ENOG4105E09	nadh pyrophosphatase
AN947_06720	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AN947_06725	ENOG41062JF	Transcriptional regulator
AN947_06735	ENOG41063SB	peptidase
AN947_06740	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AN947_06750	ENOG4105C8P	)-transporter
AN947_06755	ENOG4105DJ4	phosphatidylserine decarboxylase
AN947_06760	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AN947_06765	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AN947_06810	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AN947_06815	ENOG4105K8N	protein family UPF0079, ATPase
AN947_06820	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AN947_06825	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AN947_06830	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AN947_06835	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AN947_06840	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AN947_06845	ENOG4107QJR	hflk protein
AN947_06850	ENOG4105EPW	hflc protein
AN947_06860	ENOG41069P5	Protein slyX homolog
AN947_06870	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AN947_06875	ENOG4105WWK	YheO domain protein
AN947_06880	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
AN947_06885	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
AN947_06895	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AN947_06900	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AN947_06905	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AN947_06910	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AN947_06915	ENOG4105W53	bacterioferritin-associated ferredoxin
AN947_06920	ENOG4108UQY	Iron-storage protein
AN947_06925	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AN947_06935	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AN947_06950	ENOG4105CDU	Replicative dna helicase
AN947_06955	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AN947_06960	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
AN947_06965	ENOG4107QP8	phosphohexose isomerase
AN947_06980	ENOG4105MYN	Zinc uptake regulation protein
AN947_06985	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AN947_06990	ENOG4105P4Z	Phage shock protein G
AN947_07010	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AN947_07020	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AN947_07055	ENOG4105EEQ	Na H antiporter
AN947_07060	ENOG4105C3R	Methionine synthase
AN947_07065	ENOG4105CFH	Aspartokinase
AN947_07070	ENOG4105C5R	Aminotransferase
AN947_07080	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AN947_07085	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AN947_07090	ENOG41086KC	Transcriptional regulator
AN947_07095	ENOG4108UUM	single-stranded DNA-binding protein
AN947_07100	ENOG41062P1	Diguanylate cyclase phosphodiesterase
AN947_07120	ENOG4105E4G	Type IV pilus
AN947_07135	ENOG4107QHF	type ii secretion system protein e
AN947_07140	ENOG4105D7Q	type ii secretion system
AN947_07150	ENOG4105X0D	Fimbrial protein
AN947_07185	ENOG4105DFF	Rod shape-determining protein mreb
AN947_07190	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AN947_07195	ENOG4105VQ7	Rod shape-determining protein MreD
AN947_07200	ENOG4108Z03	MAF-like protein
AN947_07210	ENOG4105QD6	exported protein
AN947_07220	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AN947_07225	ENOG4105CEU	Arginine dihydrolase
AN947_07245	ENOG41081QV	Universal stress protein
AN947_07260	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
AN947_07265	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AN947_07270	ENOG4105D5Q	Arginine ornithine antiporter
AN947_07275	ENOG4105D5Q	Arginine ornithine antiporter
AN947_07280	ENOG4105EAH	synthase
AN947_07285	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AN947_07290	ENOG4105K46	50S ribosomal protein l27
AN947_07295	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AN947_07300	ENOG4105DWK	Membrane
AN947_07305	ENOG4107XM3	UPF0442 protein
AN947_07315	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AN947_07320	ENOG4105NWN	ApaG protein
AN947_07325	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AN947_07330	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AN947_07335	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AN947_07340	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AN947_07345	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
AN947_07400	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
AN947_07405	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
AN947_07410	ENOG4105CEN	a g-specific adenine glycosylase
AN947_07415	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AN947_07425	ENOG4105CSA	Coproporphyrinogen iii oxidase
AN947_07430	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AN947_07440	ENOG4105VZ9	UPF0235 protein
AN947_07445	ENOG4108VIA	integral membrane protein
AN947_07450	ENOG4105II7	pyrroline-5-carboxylate reductase
AN947_07455	ENOG4105DFA	alanine racemase domain protein
AN947_07460	ENOG4105CZX	twitching motility protein
AN947_07465	ENOG4105CZX	twitching motility protein
AN947_07475	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AN947_07480	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AN947_07485	ENOG4108UJU	UPF0301 protein
AN947_07490	ENOG4105D7Z	glutathione synthase
AN947_07495	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AN947_07500	ENOG4105RWS	endonuclease I
AN947_07505	ENOG4105GPY	SprT protein
AN947_07510	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AN947_07525	ENOG4108R4R	Iron-regulated virulence regulatory protein
AN947_07530	ENOG4105D05	Receptor
AN947_07535	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AN947_07540	ENOG4105BZA	Phosphoglycerate kinase
AN947_07545	ENOG4105D2N	Aldolase
AN947_07555	ENOG4105D64	Mechanosensitive ion channel
AN947_07560	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
AN947_07565	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
AN947_07570	ENOG4105MPN	Membrane
AN947_07575	ENOG4105CA9	Pyruvate kinase
AN947_07580	ENOG410804X	Transcriptional regulator
AN947_07585	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AN947_07590	ENOG4105CH5	extracellular solute-binding protein, family 7
AN947_07640	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AN947_07665	ENOG4105DR5	peptidase
AN947_07700	ENOG4108YGG	dna repair protein
AN947_07710	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AN947_07720	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_07725	ENOG4105D58	Diguanylate phosphodiesterase
AN947_07730	ENOG4105DFP	Integrase
AN947_07740	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AN947_07745	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AN947_07750	ENOG4105KTH	gatB Yqey
AN947_07755	ENOG4105VCC	30S ribosomal protein S21
AN947_07760	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AN947_07770	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AN947_07775	ENOG4107ZVW	dihydroneopterin aldolase
AN947_07780	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AN947_07795	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AN947_07800	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AN947_07805	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AN947_07810	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AN947_07815	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AN947_07820	ENOG4108K5P	(LipO)protein
AN947_07825	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AN947_07830	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AN947_07835	ENOG4105C6T	cysteine synthase
AN947_07840	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
AN947_07845	ENOG4108I5D	sulfate abc transporter
AN947_07850	ENOG4105ECW	sulfate abc transporter
AN947_07855	ENOG4108IJ6	ABC transporter
AN947_07865	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AN947_07870	ENOG4105Y3E	Modulates RecA activity (By similarity)
AN947_07875	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AN947_07880	ENOG4105CFH	Aspartokinase
AN947_07885	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AN947_07940	ENOG4107QSA	Oxaloacetate decarboxylase
AN947_07945	ENOG4105D9Q	decarboxylase (Beta subunit)
AN947_07955	ENOG4105W39	Membrane
AN947_07965	ENOG4105D9M	gamma-glutamylcysteine synthetase
AN947_07970	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AN947_07975	ENOG4108JU6	CBS domain protein
AN947_07980	ENOG4106KVJ	cytochrome C assembly protein
AN947_07985	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AN947_07990	ENOG4105K5M	30s ribosomal protein S16
AN947_07995	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AN947_08000	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AN947_08005	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AN947_08010	ENOG4105C0H	protease
AN947_08015	ENOG4105C0H	protease
AN947_08025	ENOG4105D6Z	AFG1 family ATPase
AN947_08035	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AN947_08040	ENOG4108UJD	30S ribosomal protein S9
AN947_08045	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AN947_08050	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AN947_08055	ENOG4105EIX	cytochrome c1
AN947_08060	ENOG4107MKT	Stringent starvation protein a
AN947_08065	ENOG4105KB2	stringent starvation protein b
AN947_08070	ENOG4105W4M	Transport-associated protein
AN947_08075	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AN947_08080	ENOG41082RQ	UPF0102 protein
AN947_08085	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
AN947_08090	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AN947_08095	ENOG410630P	Transcriptional regulator
AN947_08100	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AN947_08110	ENOG4105CHH	sulfate transporter
AN947_08115	ENOG4105DA5	(ABC) transporter
AN947_08120	ENOG4105E3A	(ABC) transporter
AN947_08125	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AN947_08130	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AN947_08135	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AN947_08140	ENOG4105DJ0	Poly(A) Polymerase
AN947_08145	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AN947_08150	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AN947_08165	ENOG4105CQ7	ATP-dependent helicase
AN947_08175	ENOG4105D78	K07001 NTE family protein
AN947_08185	ENOG4105XTV	UPF0231 protein
AN947_08190	ENOG4108YZA	Nitrogen regulatory protein pii
AN947_08210	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AN947_08220	ENOG4105E2V	Glycosyltransferase 36
AN947_08225	ENOG4105E2D	ec 3.2.1.52
AN947_08230	ENOG4105RD7	BadF BadG BcrA BcrD
AN947_08240	ENOG4108JQ7	(ABC) transporter
AN947_08245	ENOG4105C3U	ABC transporter
AN947_08250	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AN947_08260	ENOG4107QRA	Extracellular solute-binding protein, family 5
AN947_08270	ENOG4105BZU	Histidine kinase
AN947_08275	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AN947_08280	ENOG4105IPI	Membrane
AN947_08290	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AN947_08300	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AN947_08315	ENOG4105DR5	peptidase
AN947_08320	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AN947_08325	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
AN947_08330	ENOG4105FCK	Membrane
AN947_08335	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AN947_08340	ENOG4105HBR	Rna-binding protein
AN947_08345	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AN947_08350	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AN947_08355	ENOG4105EEI	dihydropteroate synthase
AN947_08360	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AN947_08380	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AN947_08385	ENOG4105CHV	Transcription elongation factor NusA
AN947_08390	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AN947_08395	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AN947_08400	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AN947_08405	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AN947_08410	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AN947_08415	ENOG4105RT1	May be involved in cell division (By similarity)
AN947_08430	ENOG4106RZ4	Peptidase U32
AN947_08435	ENOG4105CFP	Peptidase U32
AN947_08440	ENOG4105BZU	Histidine kinase
AN947_08445	ENOG4105XPQ	lipid carrier protein
AN947_08450	ENOG4108YYD	acetyltransferase
AN947_08465	ENOG4105BZU	Histidine kinase
AN947_08515	ENOG4105KT5	UmuD protein
AN947_08580	ENOG4105ESI	atpase involved in dna repair
AN947_08610	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
AN947_08655	ENOG4105T95	Thiol disulfide interChange protein
AN947_08705	ENOG4105RWS	endonuclease I
AN947_08720	ENOG4108UUM	single-stranded DNA-binding protein
AN947_08735	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
AN947_08760	ENOG4108YGG	dna repair protein
AN947_08780	ENOG4105BZU	Histidine kinase
AN947_08785	ENOG4105BZU	Histidine kinase
AN947_08845	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AN947_08850	ENOG4105C1J	atp-dependent rna helicase
AN947_08855	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
AN947_08860	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
AN947_08865	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AN947_08870	ENOG4105CRK	lysyL-tRNA synthetase
AN947_08875	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AN947_08885	ENOG4105CPC	Aldo Keto reductase
AN947_08890	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
AN947_08900	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AN947_08905	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
AN947_08910	ENOG4105HF0	Membrane
AN947_08915	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AN947_08920	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AN947_08930	ENOG41063Z6	transcriptional regulator, lysR family
AN947_08935	ENOG41080HT	Transcriptional regulator, arsr family
AN947_08940	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AN947_08950	ENOG4105DTN	riboflavin biosynthesis protein ribF
AN947_08955	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AN947_08960	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AN947_08965	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AN947_08970	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AN947_08990	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AN947_08995	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AN947_09000	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AN947_09005	ENOG4108NEV	two component transcriptional regulator, LytTR family
AN947_09010	ENOG4108HRK	Histidine kinase
AN947_09015	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AN947_09030	ENOG4105C5H	ABC transporter
AN947_09035	ENOG4107SC1	transglycosylase
AN947_09040	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
AN947_09045	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AN947_09050	ENOG4108K0B	C-di-gmp phosphodiesterase
AN947_09055	ENOG4107XW0	Spermidine putrescine ABC transporter periplasmic spermidine putrescine-binding protein
AN947_09065	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
AN947_09070	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AN947_09075	ENOG4105C34	Pseudouridine synthase
AN947_09080	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AN947_09085	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AN947_09130	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AN947_09135	ENOG4105CFP	Peptidase U32
AN947_09140	ENOG4105DH7	May be involved in recombination (By similarity)
AN947_09145	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AN947_09150	ENOG4105BZU	Histidine kinase
AN947_09160	ENOG4105C9X	ppx gppa phosphatase
AN947_09165	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AN947_09170	ENOG4105C8U	phosphate abc transporter
AN947_09175	ENOG4105E2Z	phosphate ABC transporter (Permease
AN947_09180	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AN947_09190	ENOG4105CSR	polyphosphate kinase 2
AN947_09200	ENOG4105D3R	alkyl hydroperoxide reductase
AN947_09205	ENOG4105C5Q	Transcriptional regulator
AN947_09215	ENOG4108I9X	Isocitrate lyase
AN947_09220	ENOG4105W87	Cbs domain
AN947_09225	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AN947_09235	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AN947_09240	ENOG4105VIE	preprotein translocase, subunit YajC
AN947_09245	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AN947_09250	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AN947_09255	ENOG4105ECY	inositol monophosphatase
AN947_09260	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
AN947_09265	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
AN947_09270	ENOG4105C3J	Cysteine desulfurase
AN947_09275	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
AN947_09280	ENOG4108Z4V	iron-sulfur cluster assembly
AN947_09285	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
AN947_09290	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AN947_09295	ENOG4108ZIT	Ferredoxin, 2FE-2S
AN947_09300	ENOG4105WVQ	Fe-S assembly protein IscX
AN947_09305	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AN947_09310	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AN947_09315	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AN947_09325	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AN947_09330	ENOG4105CUT	histidyl-tRNA synthetase
AN947_09335	ENOG4105N21	Membrane
AN947_09340	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AN947_09345	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AN947_09360	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AN947_09365	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AN947_09370	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AN947_09380	ENOG4106HK8	GPR1 FUN34 yaaH family protein
AN947_09385	ENOG4105WQI	isochorismatase
AN947_09390	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
AN947_09395	ENOG4105E4F	Isochorismate synthase
AN947_09400	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
AN947_09410	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
AN947_09415	ENOG4105DQ5	transport system permease protein
AN947_09420	ENOG4105TVJ	transport system, permease
AN947_09425	ENOG4105E0A	ABC, transporter
AN947_09435	ENOG41064T2	transcriptional regulator, lysR family
AN947_09440	ENOG4105EUZ	Beta-lactamase domain protein
AN947_09445	ENOG4105BZG	amino acid carrier protein
AN947_09450	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AN947_09470	ENOG4106YYS	transcriptional regulatory protein
AN947_09475	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AN947_09480	ENOG4105D9Q	decarboxylase (Beta subunit)
AN947_09485	ENOG4107QSA	Oxaloacetate decarboxylase
AN947_09500	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
AN947_09505	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
AN947_09510	ENOG4105CI0	Citrate lyase
AN947_09515	ENOG4105CHY	citrate lyase, alpha
AN947_09520	ENOG4105YGP	holo-ACP synthase CitX
AN947_09525	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
AN947_09540	ENOG4108Z4U	Ferredoxin
AN947_09545	ENOG4105DZ0	fad dependent oxidoreductase
AN947_09615	ENOG4105C26	Dehydrogenase
AN947_09635	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
AN947_09640	ENOG4107RK6	Methyl-accepting chemotaxis
AN947_09655	ENOG4105XB6	Toxin coregulated pilin
AN947_09670	ENOG4105GRU	toxin co-regulated pilus biosynthesis outer membrane protein C
AN947_09690	ENOG4107QHF	type ii secretion system protein e
AN947_09695	ENOG4108VEY	type ii secretion system
AN947_09710	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AN947_09730	ENOG4105DR5	peptidase
AN947_09740	ENOG4105F88	accessory colonization factor AcfD
AN947_09750	ENOG4105DFP	Integrase
AN947_09755	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AN947_09760	ENOG4108Z1B	Cyclase dehydrase
AN947_09765	ENOG4105VDB	UPF0125 protein
AN947_09770	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AN947_09775	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AN947_09780	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AN947_09785	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AN947_09790	ENOG4105CFG	Acts as a chaperone (By similarity)
AN947_09795	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AN947_09830	ENOG4105CFC	Transporter
AN947_09835	ENOG4108Z6B	deaminase
AN947_09845	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
AN947_09855	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AN947_09860	ENOG4108RS6	transposase
AN947_09885	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AN947_09890	ENOG4108R96	Methyltransferase, YaeB family
AN947_09895	ENOG4105NRA	50s ribosomal protein l31 type b
AN947_09905	ENOG4105CFC	Transporter
AN947_09910	ENOG4108UPT	UPF0178 protein
AN947_09920	ENOG4108428	Inherit from COG: -acetyltransferase
AN947_09935	ENOG4105WP7	tRNA pseudouridine synthase C
AN947_09940	ENOG4105DR9	pseudouridine synthase
AN947_09945	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AN947_09950	ENOG4105CTB	Polyprenyl synthetase
AN947_09960	ENOG4105E14	MotA TolQ exbB proton channel
AN947_09970	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AN947_09980	ENOG4105ETT	transcriptional Regulator, LysR family
AN947_09985	ENOG4105M08	Membrane
AN947_09990	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
AN947_09995	ENOG4105EWT	decarboxylase family
AN947_10000	ENOG4105BZU	Histidine kinase
AN947_10010	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AN947_10015	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
AN947_10020	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
AN947_10025	ENOG4105D01	(LipO)protein
AN947_10030	ENOG4108UMI	ABC transporter, permease
AN947_10035	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AN947_10040	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
AN947_10045	ENOG4105D4X	repressor
AN947_10050	ENOG4105C5Y	PTS System
AN947_10055	ENOG4105CG3	alpha amylase, catalytic region
AN947_10090	ENOG4107ZF2	Phosphatase
AN947_10095	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AN947_10105	ENOG4108UW5	maltose o-acetyltransferase
AN947_10125	ENOG4105D7W	serine acetyltransferase
AN947_10135	ENOG4105Q84	sucrose synthase
AN947_10145	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
AN947_10160	ENOG4108MA4	Peptidase M66
AN947_10175	ENOG4105D3Q	Sugar transferase
AN947_10185	ENOG4105DAY	polysaccharide export protein
AN947_10190	ENOG4105D75	Capsular exopolysaccharide family
AN947_10210	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AN947_10225	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AN947_10230	ENOG4108Z43	UPF0250 protein
AN947_10240	ENOG4105DZ1	carboxypeptidase
AN947_10245	ENOG4105K6T	rare lipoprotein A
AN947_10250	ENOG4105CNI	cell division protein FtsW
AN947_10255	ENOG4105CJN	penicillin-binding protein
AN947_10260	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AN947_10265	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
AN947_10270	ENOG4105DJF	DNA polymerase III, delta' subunit
AN947_10275	ENOG4108U2H	Rare lipoprotein B
AN947_10280	ENOG4105C8T	Leucyl-tRNA synthetase
AN947_10285	ENOG4107PAI	alpha helical protein
AN947_10290	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AN947_10295	ENOG4108JU5	Magnesium and cobalt efflux protein
AN947_10300	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AN947_10305	ENOG4105C9A	Phoh family
AN947_10310	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AN947_10315	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AN947_10320	ENOG4105C5Y	PTS System
AN947_10330	ENOG4105KZ7	phosphocarrier protein hpr
AN947_10340	ENOG4105C6T	cysteine synthase
AN947_10345	ENOG4105EXN	Sulfate transport protein CysZ
AN947_10350	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
AN947_10355	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AN947_10370	ENOG4108Z6Z	Transcriptional regulator
AN947_10375	ENOG4105G5H	Membrane
AN947_10380	ENOG4107QX8	SPFH domain, Band 7 family protein
AN947_10385	ENOG4107QR8	Thioredoxin
AN947_10390	ENOG4105E1F	short-chain dehydrogenase reductase
AN947_10395	ENOG4105ECP	epimerase
AN947_10400	ENOG4108RE9	Phosphodiesterase
AN947_10415	ENOG4108TU9	TRANSCRIPTIONal
AN947_10420	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AN947_10425	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AN947_10430	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AN947_10435	ENOG4105DUX	Transporter
AN947_10440	ENOG4105MDZ	Transcriptional activator rfaH
AN947_10445	ENOG4105CAQ	asparagine synthetase
AN947_10450	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AN947_10455	ENOG4105E2R	ROK family
AN947_10465	ENOG4105CI1	PTS System
AN947_10480	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AN947_10485	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AN947_10490	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AN947_10495	ENOG4108S3P	Sporulation domain protein
AN947_10500	ENOG4105E96	Colicin v production protein
AN947_10505	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AN947_10510	ENOG4105D3Y	Na H antiporter
AN947_10515	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AN947_10525	ENOG4105EIY	sodium-type flagellar protein motY
AN947_10530	ENOG4106WH9	Protein of unknown function (DUF2753)
AN947_10535	ENOG4108UYE	Lactoylglutathione lyase
AN947_10540	ENOG4105CSM	endonuclease III
AN947_10545	ENOG4105DZB	Electron transport complex
AN947_10550	ENOG4108UQQ	Electron transport complex
AN947_10555	ENOG4105D6A	Electron transport complex
AN947_10565	ENOG4108R3D	Electron transport complex
AN947_10580	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AN947_10590	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AN947_10600	ENOG4105CHW	UPF0052 protein
AN947_10605	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AN947_10610	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AN947_10615	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AN947_10620	ENOG4105M00	molybdopterin converting factor, subunit 1
AN947_10625	ENOG4108ZAF	Molybdopterin
AN947_10630	ENOG4105BZU	Histidine kinase
AN947_10650	ENOG4108I5U	Uridine phosphorylase
AN947_10660	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AN947_10665	ENOG4105D1F	ATP-binding protein
AN947_10675	ENOG4105DBI	uridine monophosphokinase
AN947_10680	ENOG4108GAE	asmA family
AN947_10685	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
AN947_10695	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AN947_10720	ENOG4105CHU	acetyl-coa acetyltransferase
AN947_10725	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AN947_10730	ENOG41069NU	Nitroreductase
AN947_10735	ENOG4105EJC	lysr family transcriptional regulator
AN947_10740	ENOG4105I93	response regulator
AN947_10750	ENOG4105WD1	Membrane
AN947_10755	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AN947_10760	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AN947_10765	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AN947_10770	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AN947_10775	ENOG4105KRS	Proteinase inhibitor
AN947_10785	ENOG4105UBK	short-chain dehydrogenase reductase
AN947_10790	ENOG4105ERU	peptidase
AN947_10800	ENOG4108XM1	transcriptional regulator AsnC family
AN947_10805	ENOG4105C29	acyl-CoA thioesterase
AN947_10825	ENOG4105BZU	Histidine kinase
AN947_10830	ENOG41082YX	Transcriptional regulator, arsr family
AN947_10835	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AN947_10860	ENOG4108V1U	phospholipid-binding protein
AN947_10880	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AN947_10895	ENOG4107YTP	response regulator receiver protein
AN947_10905	ENOG4105BZU	Histidine kinase
AN947_10910	ENOG4105BZU	Histidine kinase
AN947_10915	ENOG4105BZU	Histidine kinase
AN947_10920	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AN947_10935	ENOG4107QSI	ABC, transporter
AN947_10940	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AN947_10945	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AN947_10950	ENOG4105C3U	ABC transporter
AN947_10955	ENOG4108JQ7	(ABC) transporter
AN947_10960	ENOG4105CHF	Glutathione S-transferase
AN947_10965	ENOG4108DNC	Involved in acetate metabolism (By similarity)
AN947_10970	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AN947_10975	ENOG4105PQ6	UPF0208 membrane protein
AN947_10980	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
AN947_10990	ENOG4105C7J	ABC transporter, permease
AN947_10995	ENOG4108JJB	ABC transporter
AN947_11000	ENOG4105BZU	Histidine kinase
AN947_11005	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
AN947_11010	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AN947_11020	ENOG4105D1H	recombination factor protein RarA
AN947_11025	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AN947_11035	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AN947_11040	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AN947_11045	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AN947_11050	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AN947_11085	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AN947_11095	ENOG4105RHG	
AN947_11105	ENOG4107QTF	adenylosuccinate lyase
AN947_11110	ENOG41075W9	High frequency lysogenization protein HflD homolog
AN947_11120	ENOG4107RE1	Inosine-guanosine kinase
AN947_11130	ENOG4107S6Z	Na H antiporter
AN947_11135	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AN947_11140	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AN947_11145	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AN947_11150	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AN947_11155	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AN947_11160	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AN947_11165	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AN947_11170	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AN947_11175	ENOG4108R99	pseudouridine synthase
AN947_11185	ENOG4105VEQ	Cold shock protein
AN947_11190	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AN947_11195	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AN947_11205	ENOG41090BQ	Glutaredoxin
AN947_11210	ENOG4108EKI	Dehydrogenase
AN947_11215	ENOG4106KNT	transcriptional regulator
AN947_11220	ENOG4105DY8	decarboxylase
AN947_11230	ENOG4105DWU	Membrane
AN947_11255	ENOG4105CUX	Signal transduction histidine kinase
AN947_11265	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AN947_11280	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AN947_11285	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
AN947_11290	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
AN947_11295	ENOG41081XQ	Conserved Protein
AN947_11300	ENOG4105C9M	aspartyl-trna synthetase
AN947_11305	ENOG4107104	thymidine kinase
AN947_11310	ENOG4105CK2	sodium dicarboxylate symporter
AN947_11315	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AN947_11320	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AN947_11325	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AN947_11330	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AN947_11335	ENOG4105DDQ	anthranilate synthase
AN947_11340	ENOG4105CRQ	synthase (Component I)
AN947_11350	ENOG4105DB7	PHP domain protein
AN947_11355	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AN947_11360	ENOG4105FE9	pseudouridine synthase
AN947_11365	ENOG4108JJ8	(ABC) transporter
AN947_11370	ENOG4108JJ9	ABC, transporter
AN947_11375	ENOG4105C3M	thioredoxin reductase
AN947_11385	ENOG4105C9B	Cysteine desulfurase
AN947_11390	ENOG4105BZU	Histidine kinase
AN947_11395	ENOG4107GZ4	SanA protein
AN947_11405	ENOG4107R1I	NAD-dependent malic enzyme
AN947_11415	ENOG4105C8V	SAICAR synthetase
AN947_11435	ENOG4108ZG0	Ompa motb domain protein
AN947_11450	ENOG4105CQB	FAD linked oxidase domain protein
AN947_11460	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
AN947_11470	ENOG4105C84	Histidine ammonia-lyase
AN947_11475	ENOG4105CGP	Urocanate hydratase
AN947_11480	ENOG41088SP	formiminoglutamate hydrolase
AN947_11485	ENOG4105CI2	imidazolone-5-propionate hydrolase
AN947_11490	ENOG4105CZE	histidine utilization repressor
AN947_11505	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AN947_11515	ENOG4105BZU	Histidine kinase
AN947_11520	ENOG4105CQ2	DNA polymerase
AN947_11525	ENOG4105WH1	Two component transcriptional regulator luxr family
AN947_11530	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AN947_11560	ENOG4105BZU	Histidine kinase
AN947_11570	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AN947_11575	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AN947_11595	ENOG4105FQ6	thiopurine methyltransferase
AN947_11605	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AN947_11615	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
AN947_11620	ENOG41067MG	lrgb family
AN947_11630	ENOG4105CJB	Exodeoxyribonuclease I
AN947_11635	ENOG4108ETY	sodium dicarboxylate symporter
AN947_11640	ENOG4105E0X	reductase
AN947_11645	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
AN947_11650	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AN947_11655	ENOG4108YZT	Adenosylcobinamide kinase
AN947_11670	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
AN947_11675	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
AN947_11690	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_11715	ENOG4107QK7	reductase
AN947_11720	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AN947_11725	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AN947_11730	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AN947_11735	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AN947_11740	ENOG4105C72	UPF0176 protein
AN947_11750	ENOG4105S8Q	sugar efflux transporter
AN947_11760	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
AN947_11785	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
AN947_11790	ENOG4105EAQ	(twin-arginine translocation) pathway signal
AN947_11795	ENOG4105C5X	domain protein
AN947_11810	ENOG4105CH5	extracellular solute-binding protein, family 7
AN947_11820	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AN947_11835	ENOG41067TZ	transcriptional regulator, MarR family
AN947_11840	ENOG4105C94	Transporter
AN947_11850	ENOG4105VZJ	PTS System
AN947_11860	ENOG4105VCP	PTS System
AN947_11865	ENOG4105F8D	glycoside hydrolase family 4
AN947_11870	ENOG410901P	UPF0249 protein
AN947_11875	ENOG41060NJ	transcriptional regulator
AN947_11880	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
AN947_11885	ENOG4105DJ9	glucan biosynthesis protein
AN947_11890	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_11905	ENOG4105CGF	Aromatic amino acid aminotransferase
AN947_11915	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AN947_11925	ENOG4105C5S	asparaginyl-tRNA synthetase
AN947_11930	ENOG4108NVR	Methyl-accepting chemotaxis
AN947_11935	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AN947_11940	ENOG4105EJQ	L-serine dehydratase
AN947_11945	ENOG4105C44	Serine transporter
AN947_11950	ENOG4105P8F	nudix hydrolase
AN947_11955	ENOG4105CRQ	synthase (Component I)
AN947_11970	ENOG4105CM6	amino acid regulated cytosolic protein
AN947_11980	ENOG4108JU8	Transcriptional regulator
AN947_11985	ENOG4105D9U	N-acetyltransferase
AN947_12000	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AN947_12005	ENOG4108NVR	Methyl-accepting chemotaxis
AN947_12010	ENOG4105C8P	)-transporter
AN947_12015	ENOG4105BZU	Histidine kinase
AN947_12020	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AN947_12025	ENOG4108MJ5	VirK protein
AN947_12035	ENOG4105EB3	Histidine kinase
AN947_12040	ENOG4107EXC	regulatoR
AN947_12080	ENOG4107SDZ	Galactoside transport system permease protein mglC
AN947_12110	ENOG41073TP	transcriptional regulator
AN947_12115	ENOG4105CR4	methylisocitrate lyase
AN947_12120	ENOG4105BZN	citrate synthase
AN947_12125	ENOG4108I0Z	Aconitate hydratase
AN947_12130	ENOG4105C7F	AcnD-accessory protein PrpF
AN947_12135	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AN947_12150	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AN947_12155	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AN947_12160	ENOG4105F1J	Homogentisate 1,2-dioxygenase
AN947_12170	ENOG4108RXX	maleylacetoacetate isomerase
AN947_12175	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AN947_12200	ENOG4105DR4	Methyltransferase
AN947_12205	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
AN947_12210	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
AN947_12215	ENOG4108MN8	Membrane
AN947_12220	ENOG4105CDA	abc transporter atp-binding protein
AN947_12225	ENOG4105DRP	amino acid AbC transporter
AN947_12230	ENOG4105EZ7	amino acid ABC transporter
AN947_12235	ENOG4107QXX	ABC transporter
AN947_12245	ENOG410667J	hydrolase
AN947_12250	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AN947_12255	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AN947_12285	ENOG4105BZU	Histidine kinase
AN947_12290	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AN947_12295	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AN947_12305	ENOG4105BZU	Histidine kinase
AN947_12335	ENOG4105CQ7	ATP-dependent helicase
AN947_12345	ENOG4105R8A	Heat shock protein
AN947_12350	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
AN947_12360	ENOG4105EJC	lysr family transcriptional regulator
AN947_12365	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AN947_12370	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AN947_12375	ENOG4105KPY	Small multidrug resistance protein
AN947_12380	ENOG4108NVR	Methyl-accepting chemotaxis
AN947_12385	ENOG4108VYJ	response regulator receiver protein
AN947_12400	ENOG4105CBS	Chea signal transduction histidine kinase
AN947_12405	ENOG4105BZU	Histidine kinase
AN947_12415	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AN947_12420	ENOG4108V3W	Chemotaxis protein, CheW
AN947_12425	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_12430	ENOG4108N3W	hemolysin secretion protein
AN947_12435	ENOG4107SDU	Methyl-accepting chemotaxis
AN947_12440	ENOG4105C1J	atp-dependent rna helicase
AN947_12450	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AN947_12455	ENOG4105CW7	secretion protein, HlyD family
AN947_12460	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AN947_12465	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_12470	ENOG4105CTD	carboxy-peptidase
AN947_12475	ENOG4108WC9	type VI secretion system effector, hcp1 family
AN947_12480	ENOG4105CS6	Rhs element vgr protein
AN947_12505	ENOG410829K	Lysine exporter protein (Lyse ygga)
AN947_12510	ENOG4105BZG	amino acid carrier protein
AN947_12525	ENOG4107RUE	extracellular solute-binding protein family 1
AN947_12530	ENOG4107RUE	extracellular solute-binding protein family 1
AN947_12535	ENOG4105D38	putrescine abc transporter
AN947_12540	ENOG4105F38	ABC transporter, permease
AN947_12545	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AN947_12565	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AN947_12570	ENOG4105Q9Y	Universal stress protein
AN947_12575	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AN947_12590	ENOG4105C59	p-type ATPase
AN947_12600	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
AN947_12615	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
AN947_12630	ENOG4105BZU	Histidine kinase
AN947_12655	ENOG4108RC6	RTX toxin
AN947_12660	ENOG4105EUK	rtx toxin RtxA
AN947_12665	ENOG4105MQ5	zona occludens toxin
AN947_12690	ENOG4105VZ1	Replication Protein
AN947_12700	ENOG41067QW	Transcriptional regulator
AN947_12705	ENOG4105MQ5	zona occludens toxin
AN947_12735	ENOG4105TIV	Cryptic phage CTXphi transcriptional repressor RstR
AN947_12745	ENOG4107927	Cholera enterotoxin, A subunit
AN947_12750	ENOG4105MQ5	zona occludens toxin
AN947_12775	ENOG4105VZ1	Replication Protein
AN947_12865	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
AN947_12870	ENOG4105DAN	ATP-dependent protease
AN947_12875	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AN947_12890	ENOG4105C5H	ABC transporter
AN947_12900	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AN947_12905	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
AN947_12910	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AN947_12915	ENOG4105C7I	Dehydrogenase
AN947_12925	ENOG4105CD8	aminopeptidase N
AN947_12935	ENOG4105CN1	protease
AN947_12945	ENOG4108ZGC	gaf domain protein
AN947_12950	ENOG4105BZ1	(ABC) transporter
AN947_12955	ENOG4105H2K	paraquat-inducible protein a
AN947_12960	ENOG4105DY2	Paraquat-inducible protein b
AN947_12965	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AN947_12970	ENOG4105QNR	S1 RNA binding domain protein
AN947_12985	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AN947_12995	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AN947_13010	ENOG4105QAX	Iron-sulfur
AN947_13015	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AN947_13025	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
AN947_13045	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AN947_13050	ENOG4105C5H	ABC transporter
AN947_13055	ENOG4105BZU	Histidine kinase
AN947_13060	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AN947_13070	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
AN947_13075	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AN947_13080	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AN947_13085	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AN947_13110	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
AN947_13115	ENOG4106IUH	DTW domain containing protein
AN947_13125	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_13130	ENOG4107TT5	NLP P60 protein
AN947_13140	ENOG4105FGM	Fructosamine kinase
AN947_13150	ENOG4107QI1	Mate efflux family protein
AN947_13170	ENOG41067XB	TonB family
AN947_13175	ENOG4109015	Biopolymer transport protein exbD tolR
AN947_13205	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
AN947_13215	ENOG4105E98	transcriptional regulator DeoR family
AN947_13220	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
AN947_13225	ENOG4105XEP	YhcH YjgK YiaL family protein
AN947_13230	ENOG4105M4H	endoribonuclease L-psp
AN947_13235	ENOG4105DDV	Transcriptional regulator (LacI family
AN947_13240	ENOG4105CS2	ec 3.2.1.21
AN947_13260	ENOG4107QZV	Type I secretion membrane fusion protein
AN947_13270	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AN947_13275	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AN947_13280	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AN947_13285	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AN947_13290	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AN947_13300	ENOG4105C9Q	fumarate hydratase class II
AN947_13330	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
AN947_13335	ENOG4105DUM	transcriptional regulator, lysR family
AN947_13340	ENOG4108TWJ	NADH dehydrogenase subunit 5
AN947_13350	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AN947_13360	ENOG4105CH6	catalase
AN947_13375	ENOG4107FQX	Alpha-acetolactate decarboxylase
AN947_13380	ENOG4105C7K	acetolactate synthase
AN947_13390	ENOG4105BZU	Histidine kinase
AN947_13395	ENOG4106TD9	Diguanylate cyclase
AN947_13405	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AN947_13410	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
AN947_13460	ENOG4106YYS	transcriptional regulatory protein
AN947_13465	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AN947_13480	ENOG4107V40	secretion protein, HlyD family
AN947_13500	ENOG4105CVG	Homoserine O-transsuccinylase
AN947_13505	ENOG41090FY	type IV pilus biogenesis stability protein PilW
AN947_13520	ENOG4108VKG	metal-dependent hydrolase
AN947_13530	ENOG4105F04	LysR family Transcriptional regulator
AN947_13555	ENOG4105CDV	Ompa motb domain protein
AN947_13560	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
AN947_13565	ENOG4105E3Q	saccharopine dehydrogenase
AN947_13575	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AN947_13595	ENOG4105UQX	Mate efflux family protein
AN947_13610	ENOG4105C2C	drug resistance transporter, Bcr CflA
AN947_13615	ENOG4105I08	Pseudouridine synthase
AN947_13620	ENOG4105CFI	type iii restriction protein res subunit
AN947_13640	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AN947_13660	ENOG4108N3W	hemolysin secretion protein
AN947_13690	ENOG4105KXC	Collagenase
AN947_13700	ENOG4105BZU	Histidine kinase
AN947_13705	ENOG4105BZU	Histidine kinase
AN947_13710	ENOG4105CJW	magnesium transporter
AN947_13720	ENOG4105C44	Serine transporter
AN947_13730	ENOG4105CJ1	ABC, transporter
AN947_13735	ENOG4107QWP	ABC-2 type transporter
AN947_13745	ENOG4105XZD	Fe-S protein
AN947_13755	ENOG4105VNH	ABC transporter solute-binding protein
AN947_13760	ENOG4105CXZ	ABC transporter, permease
AN947_13765	ENOG4108VGW	abc transporter atp-binding protein
AN947_13775	ENOG4108W1A	pseudouridine synthase
AN947_13780	ENOG4105C8J	)-transporter
AN947_13790	ENOG4105C28	cystathionine
AN947_13795	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AN947_13810	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AN947_13825	ENOG41087YS	Phage shock protein A
AN947_13830	ENOG4105E51	psp operon transcriptional activator
AN947_13835	ENOG4108J59	Extracellular solute-binding protein, family 5
AN947_13840	ENOG4108I5W	peptide transport system, permease protein
AN947_13845	ENOG4108EU3	peptide transport system, permease
AN947_13850	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
AN947_13855	ENOG4108JQ2	peptide transport system atp-binding protein
AN947_13870	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AN947_13890	ENOG4107QY8	reductase
AN947_13910	ENOG4105TMB	Formate nitrite transporter
AN947_13920	ENOG4108535	NAD dependent epimerase/dehydratase family
AN947_13925	ENOG4105GFG	DUF218 domain
AN947_13935	ENOG4107835	probably involved in intracellular septation (By similarity)
AN947_13945	ENOG4105K9H	YciI-like protein
AN947_13955	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AN947_13960	ENOG4105DZ2	Transcriptional regulator
AN947_13980	ENOG4105BZU	Histidine kinase
AN947_13985	ENOG4105CCT	upf0313 protein
AN947_13995	ENOG4105EW9	transcriptional regulator AsnC family
AN947_14000	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
AN947_14005	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
AN947_14010	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
AN947_14015	ENOG4106371	Methyltransferase
AN947_14020	ENOG4107S90	membrAne
AN947_14025	ENOG4106WF9	DNA-binding transcriptional regulator TorR
AN947_14030	ENOG4108SBI	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
AN947_14035	ENOG4105ETE	Transcriptional regulator (LacI family
AN947_14040	ENOG4105HP8	regulator of competence-specific genes
AN947_14060	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AN947_14065	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AN947_14070	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AN947_14075	ENOG4105RKX	Protein of unknown function (DUF2498)
AN947_14080	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AN947_14090	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AN947_14100	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AN947_14110	ENOG4107QPN	acyl-Coa dehydrogenase
AN947_14115	ENOG41067SE	Tetr family transcriptional regulator
AN947_14135	ENOG4108R86	Transcriptional regulator
AN947_14170	ENOG4105DY2	Paraquat-inducible protein b
AN947_14195	ENOG4105DFP	Integrase
AN947_14220	ENOG4108NYK	Tape measure protein
AN947_14335	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AN947_14345	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
AN947_14350	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
AN947_14355	ENOG4105C26	Dehydrogenase
AN947_14365	ENOG4105DM4	PTS System
AN947_14370	ENOG4105DM4	PTS System
AN947_14375	ENOG4108YRF	PTS System
AN947_14385	ENOG4106R3P	AraC family transcriptional regulator
AN947_14390	ENOG4105DM4	PTS System
AN947_14395	ENOG4105EIP	mannose-6-phosphate isomerase
AN947_14400	ENOG4108RNS	Exports L-alanine (By similarity)
AN947_14405	ENOG4105BZU	Histidine kinase
AN947_14415	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AN947_14425	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AN947_14430	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AN947_14440	ENOG4105M8F	Biopolymer transport protein exbD tolR
AN947_14445	ENOG4105E02	MotA TolQ exbB proton channel
AN947_14450	ENOG4107YD3	Thioesterase
AN947_14455	ENOG4105KJB	cyd operon protein YbgE
AN947_14465	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AN947_14470	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AN947_14475	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AN947_14480	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AN947_14485	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AN947_14490	ENOG4105C8N	cysteinyl-tRNA synthetase
AN947_14495	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AN947_14500	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AN947_14505	ENOG4105D58	Diguanylate phosphodiesterase
AN947_14520	ENOG4105ZU8	porin-like protein H
AN947_14525	ENOG4105DVT	helicase
AN947_14530	ENOG4105EJ9	Membrane
AN947_14535	ENOG4108URS	primosomal replication protein n''
AN947_14540	ENOG4106428	Protein of unknown function (DUF2496)
AN947_14545	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_14550	ENOG4105CGK	Exodeoxyribonuclease III
AN947_14555	ENOG4106YG3	ABC transporter
AN947_14560	ENOG4105DSP	amino acid AbC transporter
AN947_14565	ENOG4105E89	ABC transporter
AN947_14570	ENOG4108JEH	abc transporter atp-binding protein
AN947_14580	ENOG4105C6N	Formate acetyltransferase
AN947_14590	ENOG4108N3W	hemolysin secretion protein
AN947_14595	ENOG4105F1A	Pyruvate formate-lyase
AN947_14605	ENOG4105XWI	UPF0304 protein
AN947_14610	ENOG4105CYN	Serine protein kinase
AN947_14615	ENOG4106AKX	UPF0229 protein
AN947_14620	ENOG4105ED1	spovr family
AN947_14625	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AN947_14635	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AN947_14640	ENOG4105BZ1	(ABC) transporter
AN947_14645	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
AN947_14655	ENOG4105D60	lipoprotein releasing system transmembrane protein
AN947_14660	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AN947_14665	ENOG4105D60	lipoprotein releasing system transmembrane protein
AN947_14675	ENOG4108JA2	transcriptioN-repair coupling factor
AN947_14685	ENOG4106M3D	hemolysin
AN947_14695	ENOG4105CEP	NADH dehydrogenase
AN947_14725	ENOG4105K59	histidine triad (HIT) protein
AN947_14730	ENOG4108NVR	Methyl-accepting chemotaxis
AN947_14740	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
AN947_14745	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AN947_14750	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AN947_14755	ENOG4105CNU	cell division protein FtsK
AN947_14760	ENOG4105EW9	transcriptional regulator AsnC family
AN947_14765	ENOG4105DCF	alanine dehydrogenase
AN947_14775	ENOG4107R11	Transcriptional regulator
AN947_14785	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
AN947_14790	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AN947_14795	ENOG4105CFV	Tetratricopeptide repeat protein
AN947_14800	ENOG4105Q4A	inner membrane protein yciS
AN947_14805	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AN947_14810	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AN947_14815	ENOG4105CAT	Cytidine monophosphate kinase
AN947_14820	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
AN947_14825	ENOG4105EIN	peptidylprolyl cis-trans isomerase
AN947_14830	ENOG4105K70	DNA-binding protein
AN947_14835	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AN947_14840	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AN947_14845	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AN947_14850	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AN947_14865	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AN947_14870	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AN947_14875	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
AN947_14880	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AN947_14885	ENOG4105CNG	UPF0061 protein
AN947_14900	ENOG4105BZU	Histidine kinase
AN947_14910	ENOG4108HPI	phosphatidate Cytidylyltransferase
AN947_14945	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AN947_14960	ENOG4105JQN	Transcriptional regulator
AN947_14970	ENOG4107QY8	reductase
AN947_14975	ENOG4105CUW	cytochrome C-TYPE protein
AN947_14980	ENOG410662T	chitinase
AN947_14985	ENOG4105D9N	nucleoside
AN947_14990	ENOG4105JQN	Transcriptional regulator
AN947_14995	ENOG4105CVE	Lytic murein transglycosylase
AN947_15000	ENOG4105VNG	YcgL domain-containing protein
AN947_15005	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AN947_15010	ENOG4107QMS	site-determining protein
AN947_15015	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
AN947_15050	ENOG4108N3W	hemolysin secretion protein
AN947_15055	ENOG4108JCI	Transcriptional regulator
AN947_15060	ENOG4105DKK	Benzoate
AN947_15065	ENOG4105CEY	Amp-dependent synthetase and ligase
AN947_15070	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
AN947_15075	ENOG4108IPT	Naphthoate synthase
AN947_15080	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
AN947_15085	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AN947_15090	ENOG4105E4F	Isochorismate synthase
AN947_15095	ENOG4105CHM	Aminotransferase
AN947_15100	ENOG4105DK2	UPF0207 protein
AN947_15105	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AN947_15125	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
AN947_15130	ENOG4105CEY	Amp-dependent synthetase and ligase
AN947_15135	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AN947_15150	ENOG41072GX	Peptidase M22 Glycoprotease
AN947_15155	ENOG4105DVT	helicase
AN947_15165	ENOG4105CIY	formyltetrahydrofolate deformylase
AN947_15170	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AN947_15175	ENOG4105D07	Signal peptide peptidase, SppA
AN947_15180	ENOG4105HDK	L-asparaginase
AN947_15185	ENOG4105VUT	cytoplasmic protein
AN947_15195	ENOG4105E0X	reductase
AN947_15200	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AN947_15215	ENOG4105DHI	Methyltransferase
AN947_15230	ENOG4107R88	Chemotaxis protein (CheV)
AN947_15235	ENOG4105DAG	ROK family
AN947_15240	ENOG4105CA9	Pyruvate kinase
AN947_15255	ENOG4105C8J	)-transporter
AN947_15260	ENOG4105CI1	PTS System
AN947_15265	ENOG4105F8V	Hydrolase, tatD family
AN947_15270	ENOG4107QRG	dna polymerase iii
AN947_15275	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AN947_15280	ENOG4105HHA	aminodeoxychorismate lyase
AN947_15285	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
AN947_15290	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AN947_15295	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AN947_15300	ENOG4105CHR	reductase
AN947_15305	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AN947_15310	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AN947_15315	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AN947_15320	ENOG4105VGS	50s ribosomal protein l32
AN947_15325	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
AN947_15330	ENOG4108UHJ	MAF-like protein
AN947_15335	ENOG4105EI2	Pseudouridine synthase
AN947_15350	ENOG4105C03	ribonuclease
AN947_15365	ENOG4108EKI	Dehydrogenase
AN947_15370	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AN947_15375	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AN947_15380	ENOG4105DFD	Na H antiporter
AN947_15390	ENOG4106V8H	Nucleoid-associated protein
AN947_15400	ENOG4105E68	Sulfatase
AN947_15415	ENOG4105DGU	Histone deacetylase
AN947_15425	ENOG4105M2J	Glutaredoxin
AN947_15430	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AN947_15445	ENOG410903C	(LipO)protein
AN947_15455	ENOG4105KWW	Biogenesis protein
AN947_15460	ENOG4107QX9	Thiol disulfide interChange protein
AN947_15465	ENOG4105DA4	cytochrome c-type biogenesis protein
AN947_15470	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AN947_15475	ENOG41067VX	Heme exporter protein
AN947_15480	ENOG41060IM	Heme exporter protein
AN947_15485	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AN947_15490	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AN947_15500	ENOG4108V3W	Chemotaxis protein, CheW
AN947_15510	ENOG4107QJE	Chromosome Partitioning Protein
AN947_15515	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AN947_15520	ENOG4105CBS	Chea signal transduction histidine kinase
AN947_15525	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
AN947_15530	ENOG4108VYJ	response regulator receiver protein
AN947_15535	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AN947_15545	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AN947_15550	ENOG4105D7B	Flagellar biosynthesis protein flha
AN947_15555	ENOG4108BY2	phosphohistidine phosphatase
AN947_15560	ENOG4108JQM	Insulinase (Peptidase family M16)
AN947_15570	ENOG4105C75	arginyL-tRNA synthetase
AN947_15590	ENOG4105XFK	Ferrous iron transport protein A
AN947_15595	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
AN947_15600	ENOG4105NXV	High-affinity zinc uptake system protein
AN947_15605	ENOG4105FDK	ABC transporter
AN947_15610	ENOG4105FAV	ABC, transporter
AN947_15615	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AN947_15620	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AN947_15625	ENOG4105C7S	Dehydrogenase
AN947_15630	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AN947_15635	ENOG4105E33	succinate dehydrogenase
AN947_15640	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AN947_15645	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
AN947_15650	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
AN947_15655	ENOG4105BZN	citrate synthase
AN947_15660	ENOG4107QNR	UPF0135 protein
AN947_15675	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
AN947_15680	ENOG4105EV9	Alpha Beta Hydrolase
AN947_15690	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
AN947_15695	ENOG41067MG	lrgb family
AN947_15700	ENOG4105VAW	lrga family
AN947_15705	ENOG4105CMU	LysR family (Transcriptional regulator
AN947_15715	ENOG41090R7	Ferric uptake
AN947_15720	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AN947_15725	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
AN947_15730	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AN947_15735	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
AN947_15740	ENOG4105Q8W	reductase
AN947_15745	ENOG4105MH2	YfcL protein
AN947_15750	ENOG4108BPE	-transporting atpase
AN947_15755	ENOG4105EN6	Membrane
AN947_15760	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AN947_15770	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AN947_15780	ENOG4105D00	flagellar biosynthetic protein flhB
AN947_15785	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AN947_15790	ENOG4105VS8	Flagellar biosynthetic protein fliq
AN947_15795	ENOG4105CN7	Flagellar biosynthetic protein FliP
AN947_15800	ENOG4105VTB	flagellar biosynthesis protein fliO
AN947_15805	ENOG4105DD5	Flagellar motor switch protein
AN947_15810	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AN947_15815	ENOG4105X6C	Flagellar basal body-associated protein FliL
AN947_15830	ENOG4108JIR	Flagellum-specific ATP synthase
AN947_15835	ENOG4105W2B	Flagellar assembly protein
AN947_15840	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AN947_15845	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AN947_15850	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
AN947_15860	ENOG4105BZU	Histidine kinase
AN947_15865	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AN947_15870	ENOG4105MQ3	flagellar protein FliS
AN947_15880	ENOG4107W9T	flagellar hook-associated
AN947_15885	ENOG41063QE	flagellar protein FlaG
AN947_15890	ENOG4105I03	Flagellin
AN947_15895	ENOG4105I03	Flagellin
AN947_15900	ENOG4105I03	Flagellin
AN947_15905	ENOG4105EZR	dyp-type peroxidase family protein
AN947_15910	ENOG4105QZU	Inner membrane protein YfeZ
AN947_15925	ENOG4105KUZ	arsenate reductase
AN947_15930	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AN947_15945	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AN947_15950	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AN947_15960	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AN947_15965	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_15980	ENOG4105ERG	peptidase m48, ste24p
AN947_15985	ENOG4105K89	arsenate reductase
AN947_15990	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AN947_16005	ENOG4105C2W	permease
AN947_16010	ENOG4108Z66	YbaK ebsC protein
AN947_16015	ENOG4105CGH	5'-nucleotidase
AN947_16020	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AN947_16025	ENOG41063JG	Transcriptional regulator
AN947_16030	ENOG4108YY7	Invasion gene expression up-regulator SirB
AN947_16035	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AN947_16040	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AN947_16045	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AN947_16050	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
AN947_16055	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AN947_16060	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AN947_16065	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AN947_16070	ENOG4105C3G	gtp-binding protein
AN947_16145	ENOG4105I03	Flagellin
AN947_16150	ENOG4105I03	Flagellin
AN947_16170	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AN947_16175	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AN947_16180	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AN947_16185	ENOG4105CGA	flagellar basal-body rod protein FlgG
AN947_16190	ENOG4108KPB	Flagellar basal-body rod protein FlgF
AN947_16195	ENOG4105BZE	flagellar hook protein, FlgE
AN947_16200	ENOG4105W00	Flagellar hook capping protein
AN947_16205	ENOG4108ZC9	flagellar basal-body rod protein flgc
AN947_16210	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
AN947_16215	ENOG4105BZU	Histidine kinase
AN947_16220	ENOG4107R88	Chemotaxis protein (CheV)
AN947_16255	ENOG4105C0W	non-ribosomal peptide synthetase
AN947_16260	ENOG4105Q26	Siderophore-interacting protein
AN947_16265	ENOG4107RBR	Receptor
AN947_16280	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AN947_16285	ENOG4105C59	p-type ATPase
AN947_16295	ENOG4105E2D	ec 3.2.1.52
AN947_16300	ENOG4105MBR	gumn family
AN947_16315	ENOG4108DG9	Smr protein MutS2
AN947_16320	ENOG4105FE9	pseudouridine synthase
AN947_16325	ENOG4105BZU	Histidine kinase
AN947_16330	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AN947_16335	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AN947_16340	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AN947_16345	ENOG4105E7A	Glutamine amidotransferase
AN947_16350	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AN947_16355	ENOG4107QPN	acyl-Coa dehydrogenase
AN947_16365	ENOG4108JDX	DNA polymerase iii, epsilon subunit
AN947_16370	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AN947_16375	ENOG4105D1A	Methyltransferase
AN947_16380	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AN947_16385	ENOG4105E9H	Lytic Murein transglycosylase
AN947_16395	ENOG4108YZA	Nitrogen regulatory protein pii
AN947_16400	ENOG4105PY6	Phenolic acid decarboxylase
AN947_16405	ENOG4105N7H	Cytochrome
AN947_16410	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AN947_16415	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AN947_16420	ENOG4105C0B	DNA polymerase III (alpha subunit)
AN947_16425	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AN947_16430	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AN947_16435	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AN947_16440	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AN947_16445	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AN947_16450	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
AN947_16465	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AN947_16470	ENOG4105KNE	Phosphatidate cytidylyltransferase
AN947_16475	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AN947_16480	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AN947_16485	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AN947_16490	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AN947_16495	ENOG4105CE9	30S ribosomal protein S2
AN947_16500	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AN947_16505	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AN947_16510	ENOG4108T8E	UPF0325 protein
AN947_16515	ENOG4108ZAI	phosphatidylglycerophosphatase a
AN947_16520	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AN947_16525	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AN947_16530	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AN947_16545	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AN947_16550	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AN947_16555	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AN947_16560	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AN947_16565	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
AN947_16575	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
AN947_16580	ENOG4105C7N	Xanthine uracil vitamin C permease
AN947_16585	ENOG4105CIN	aminoacyl-histidine dipeptidase
AN947_16590	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AN947_16595	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AN947_16605	ENOG4105C8J	)-transporter
AN947_16610	ENOG4105BZU	Histidine kinase
AN947_16625	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AN947_16635	ENOG4105CJ2	(LipO)protein
AN947_16640	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
AN947_16645	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AN947_16650	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AN947_16655	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AN947_16660	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AN947_16665	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AN947_16670	ENOG4105M85	Bola protein
AN947_16675	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AN947_16685	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AN947_16690	ENOG4105EYM	Major Facilitator superfamily
AN947_16700	ENOG4105K6V	RNA polymerase
AN947_16710	ENOG4105DRB	nucleoside-specific channel-forming protein
AN947_16715	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AN947_16720	ENOG4107S0N	DJ-1 family
AN947_16725	ENOG4105C9B	Cysteine desulfurase
AN947_16730	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AN947_16735	ENOG4105CUZ	uba thif-type nad fad binding protein
AN947_16740	ENOG4105CA3	membrane-bound lytic murein transglycosylase
AN947_16750	ENOG4107QZM	n-acetylglutamate synthase
AN947_16765	ENOG4107QYX	exodeoxyribonuclease v alpha
AN947_16770	ENOG4107QKA	exodeoxyribonuclease V beta
AN947_16775	ENOG4105DSY	exodeoxyribonuclease V, gamma
AN947_16790	ENOG4105X2V	dna damage-inducible protein
AN947_16805	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AN947_16810	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AN947_16825	ENOG4108Y51	tRNA-binding protein
AN947_16830	ENOG41060NJ	transcriptional regulator
AN947_16835	ENOG4105CNT	hydrolase family 2
AN947_16845	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AN947_16850	ENOG4108IQE	Amp-dependent synthetase and ligase
AN947_16855	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AN947_16860	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AN947_16870	ENOG4105EAC	phosphoserine phosphatase
AN947_16880	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
AN947_16885	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
AN947_16890	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
AN947_16895	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AN947_16905	ENOG4105D9N	nucleoside
AN947_16910	ENOG4105EYA	deoxyribonuclease
AN947_16920	ENOG4105BZG	amino acid carrier protein
AN947_16935	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AN947_16940	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
AN947_16945	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
AN947_16950	ENOG4105D98	threonine synthase
AN947_16955	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AN947_16970	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AN947_16980	ENOG41065U4	response regulator
AN947_16985	ENOG4105BZU	Histidine kinase
AN947_16995	ENOG4105N5T	Radical SAM Protein
AN947_17010	ENOG4105CBC	glutamate synthase
AN947_17015	ENOG4105BZ8	glutamate synthase
AN947_17025	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AN947_17035	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AN947_17040	ENOG4105EN6	Membrane
AN947_17045	ENOG4105VP0	transcriptional regulator, lysR family
AN947_17050	ENOG4105EJ9	Membrane
AN947_17055	ENOG4107RRE	RNA-directed DNA polymerase
AN947_17080	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AN947_17085	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AN947_17095	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AN947_17100	ENOG4105M6F	mutator MutT protein
AN947_17110	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AN947_17120	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AN947_17125	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AN947_17135	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AN947_17140	ENOG4105DFU	Cell wall formation (By similarity)
AN947_17145	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AN947_17155	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AN947_17160	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AN947_17165	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AN947_17170	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AN947_17175	ENOG4105CJN	penicillin-binding protein
AN947_17180	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AN947_17185	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AN947_17190	ENOG4107QN2	dihydrolipoyl dehydrogenase
AN947_17195	ENOG4107QSN	dihydrolipoamide acetyltransferase
AN947_17200	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AN947_17205	ENOG41073TP	transcriptional regulator
AN947_17210	ENOG4105CGH	5'-nucleotidase
AN947_17215	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AN947_17220	ENOG4105T95	Thiol disulfide interChange protein
AN947_17225	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AN947_17230	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
AN947_17240	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AN947_17250	ENOG4107QHF	type ii secretion system protein e
AN947_17255	ENOG4105D7Q	type ii secretion system
AN947_17260	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AN947_17265	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AN947_17270	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
AN947_17275	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
AN947_17285	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AN947_17290	ENOG4105IPS	esterase
AN947_17295	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
AN947_17300	ENOG4108SX3	cytoplasmic protein
AN947_17305	ENOG41087AY	ADP-Ribose pyrophosphatase
AN947_17310	ENOG4105DFG	type I secretion outer membrane protein
AN947_17320	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AN947_17325	ENOG4105C8Q	Methyl-accepting chemotaxis
AN947_17330	ENOG4105I7R	Adenylate cyclase
AN947_17335	ENOG4107IX6	phosphate transport regulator
AN947_17340	ENOG4105CJ3	phosphate transporter
AN947_17345	ENOG4106MWK	domain protein
AN947_17365	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AN947_17370	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AN947_17375	ENOG4105DXN	mazG family
AN947_17380	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AN947_17385	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AN947_17390	ENOG4105BZU	Histidine kinase
AN947_17395	ENOG4108K0B	C-di-gmp phosphodiesterase
AN947_17410	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AN947_17415	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AN947_17420	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
AN947_17425	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AN947_17430	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AN947_17435	ENOG4105C3F	Signal peptidase i
AN947_17440	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AN947_17445	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
AN947_17450	ENOG4105VQK	sigma E regulatory protein, MucB RseB
AN947_17460	ENOG4105EMN	RNA polymerase sigma factor
AN947_17470	ENOG4108IYU	L-aspartate oxidase
AN947_17480	ENOG4105Y75	tpr repeat protein
AN947_17485	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AN947_17495	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AN947_17500	ENOG4105D0A	hydroxylase
AN947_17510	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
AN947_17515	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AN947_17520	ENOG4105E66	phosphoriboisomerase A
AN947_17525	ENOG4108JQ1	Dehydrogenase
AN947_17530	ENOG4108ZP8	Acetolactate synthase small subunit
AN947_17535	ENOG4105C7K	acetolactate synthase
AN947_17540	ENOG4108IQE	Amp-dependent synthetase and ligase
AN947_17545	ENOG41064T2	transcriptional regulator, lysR family
AN947_17565	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AN947_17570	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AN947_17575	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AN947_17580	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AN947_17625	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AN947_17640	ENOG4108K5H	permease YjgP YjgQ family protein
AN947_17645	ENOG4108M8S	permease YjgP YjgQ family protein
AN947_17650	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AN947_17655	ENOG4105MYG	DNA polymerase iii, chi subunit
AN947_17660	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AN947_17665	ENOG4105C5I	Dehydrogenase
AN947_17670	ENOG4105D3G	Pseudouridine synthase
AN947_17685	ENOG4108IAB	Phoh family
AN947_17690	ENOG4105DBV	ornithine carbamoyltransferase
AN947_17700	ENOG4105CXT	aspartate transcarbamylase
AN947_17705	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
AN947_17710	ENOG4105KME	endoribonuclease L-psp
AN947_17715	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
AN947_17720	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AN947_17725	ENOG4105VFK	BolA family
AN947_17735	ENOG4105E3I	toluene tolerance
AN947_17740	ENOG4107PE3	Mammalian cell entry related domain protein
AN947_17745	ENOG4105CY3	ABC transporter, permease
AN947_17750	ENOG4105DHJ	ABC, transporter
AN947_17765	ENOG4105C2X	Arabinose 5-phosphate isomerase
AN947_17770	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AN947_17780	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
AN947_17785	ENOG4108IUZ	ABC transporter
AN947_17790	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AN947_17795	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AN947_17800	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AN947_17805	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AN947_17810	ENOG41080Z8	PHOSPHOCARRIER protein
AN947_17815	ENOG4105CJW	magnesium transporter
AN947_17820	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AN947_17825	ENOG4105N42	UPF0307 protein
AN947_17830	ENOG4107T0D	ABC, transporter
AN947_17835	ENOG4106SMU	thiamine transporter membrane protein
AN947_17840	ENOG4105DP9	ABC transporter
AN947_17845	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
AN947_17850	ENOG4105DFU	Cell wall formation (By similarity)
AN947_17860	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AN947_17865	ENOG4105F0N	pyrophosphate phospho-hydrolase
AN947_17870	ENOG41066HZ	AIG2-like family
AN947_17880	ENOG4105CFU	surface antigen
AN947_17885	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AN947_17890	ENOG4108UUE	Transcriptional regulator
AN947_17905	ENOG4105C19	ABC transporter
AN947_17925	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
AN947_17930	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AN947_17935	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AN947_17940	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AN947_17945	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
AN947_17955	ENOG4105C1J	atp-dependent rna helicase
AN947_17960	ENOG4107YB6	acetyltransferase, (GNAT) family
AN947_17965	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AN947_17970	ENOG4108UBT	opacity-associated protein
AN947_17975	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AN947_17990	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AN947_17995	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AN947_18005	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AN947_18015	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AN947_18020	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AN947_18025	ENOG4105VPB	50S ribosomal protein L30
AN947_18030	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AN947_18035	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AN947_18040	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AN947_18045	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AN947_18050	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AN947_18055	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AN947_18060	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AN947_18065	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AN947_18070	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AN947_18075	ENOG41083MP	50s ribosomal protein l29
AN947_18080	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AN947_18085	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AN947_18090	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AN947_18095	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AN947_18100	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AN947_18105	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AN947_18110	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AN947_18115	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AN947_18120	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AN947_18125	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AN947_18130	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AN947_18135	ENOG4105E68	Sulfatase
AN947_18140	ENOG4108UV7	flagellar protein motX
AN947_18145	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AN947_18150	ENOG4105D44	asparaginase
AN947_18155	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AN947_18170	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
AN947_18175	ENOG4105C5H	ABC transporter
AN947_18185	ENOG4105DNZ	Alpha Beta Hydrolase
AN947_18195	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
AN947_18200	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AN947_18210	ENOG4105C26	Dehydrogenase
AN947_18220	ENOG4105C8Y	Acetylornithine aminotransferase
AN947_18225	ENOG4105DDQ	anthranilate synthase
AN947_18230	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AN947_18245	ENOG4105C31	Tryptophanyl-tRNA synthetase
AN947_18250	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AN947_18255	ENOG4105DJV	ribulose-phosphate 3-epimerase
AN947_18260	ENOG4105DFE	Dna adenine methylase
AN947_18275	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AN947_18280	ENOG4105E4G	Type IV pilus
AN947_18305	ENOG4108JQC	penicillin-binding protein 1A
AN947_18315	ENOG4105EHV	domain protein
AN947_18320	ENOG4107QN2	dihydrolipoyl dehydrogenase
AN947_18330	ENOG4105CH7	arginosuccinase
AN947_18335	ENOG4105CDH	Citrulline--aspartate ligase
AN947_18340	ENOG4105CAS	nag kinase
AN947_18345	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AN947_18350	ENOG4105CWC	Acetylornithine deacetylase
AN947_18355	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AN947_18365	ENOG4105D7W	serine acetyltransferase
AN947_18370	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AN947_18375	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AN947_18380	ENOG4107YZP	Rhodanese domain protein
AN947_18385	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
AN947_18395	ENOG4105E33	succinate dehydrogenase
AN947_18400	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
AN947_18405	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
AN947_18410	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AN947_18425	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AN947_18430	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AN947_18465	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AN947_18470	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
AN947_18475	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AN947_18480	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AN947_18485	ENOG41063M6	Cell Division Protein
AN947_18490	ENOG4105ETE	Transcriptional regulator (LacI family
AN947_18495	ENOG4105C25	Primosomal protein n'
AN947_18500	ENOG4105VFB	Binds the 23S rRNA (By similarity)
AN947_18505	ENOG4105C6K	Malic enzyme
AN947_18510	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
AN947_18515	ENOG4105C28	cystathionine
AN947_18520	ENOG4105CFH	Aspartokinase
AN947_18525	ENOG4105SYT	Methylenetetrahydrofolate reductase
AN947_18530	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
AN947_18535	ENOG4105CBT	Fructose-1,6-bisphosphatase
AN947_18540	ENOG4105CTQ	phosphohexokinase
AN947_18545	ENOG41076HS	cation diffusion facilitator family transporter
AN947_18555	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AN947_18560	ENOG4105E0F	Histidine kinase
AN947_18570	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AN947_18575	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
AN947_18580	ENOG4105BZU	Histidine kinase
AN947_18585	ENOG4108IJ0	Aspartate ammonia-lyase
AN947_18590	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
AN947_18605	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AN947_18615	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
AN947_18625	ENOG4107QN1	sodium solute
AN947_18630	ENOG4105EX9	Membrane
AN947_18635	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AN947_18640	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AN947_18645	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AN947_18650	ENOG4105CB5	ATP-dependent DNA helicase recG
AN947_18655	ENOG4105C2W	permease
AN947_18665	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AN947_18670	ENOG4108RRZ	Transcription elongation factor GreB
AN947_18675	ENOG4105BZM	domain protein
AN947_18685	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AN947_18690	ENOG4105MJ2	Competence protein
AN947_18695	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
AN947_18700	ENOG4107RK2	ADP-ribose diphosphatase NudE
AN947_18705	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AN947_18710	ENOG4105PIC	general secretion pathway protein N
AN947_18720	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
AN947_18725	ENOG4108RTD	type II secretion system protein K
AN947_18730	ENOG4108WWZ	General secretion pathway protein J
AN947_18735	ENOG4105X5Z	General secretion pathway protein I
AN947_18740	ENOG4105VWV	general secretion pathway protein h
AN947_18745	ENOG4108VAU	general secretion pathway protein G
AN947_18750	ENOG4105D7Q	type ii secretion system
AN947_18755	ENOG4107QHF	type ii secretion system protein e
AN947_18765	ENOG4108XKW	General secretion pathway protein C
AN947_18770	ENOG4105VEJ	Heat shock protein
AN947_18775	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AN947_18780	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
AN947_18790	ENOG4105SUU	thioesterase domain
AN947_18795	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AN947_18820	ENOG4105C5F	glutamine synthetase
AN947_18830	ENOG4105CUX	Signal transduction histidine kinase
AN947_18835	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AN947_18840	ENOG4105BZU	Histidine kinase
AN947_18845	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AN947_18925	ENOG4108RR8	protoporphyrinogen oxidase
AN947_18930	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AN947_18935	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AN947_18940	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AN947_18950	ENOG4105F52	Transcriptional regulator
AN947_18955	ENOG4105CZQ	inner membrane transport protein YdhC
AN947_18960	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AN947_18965	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AN947_18970	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AN947_18975	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AN947_18980	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AN947_18985	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AN947_18990	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AN947_18995	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AN947_19000	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
AN947_19005	ENOG410684E	atp synthase
AN947_19010	ENOG4105FA0	parb-like partition protein
AN947_19015	ENOG4107QJE	Chromosome Partitioning Protein
AN947_19020	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AN947_19025	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AN947_19065	ENOG4105I1F	Resistance protein
AN947_19230	ENOG4108R0M	Aminoglycoside
AN947_19275	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AN947_19290	ENOG4107QJE	Chromosome Partitioning Protein
AN947_19375	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AN947_19465	ENOG4105T95	Thiol disulfide interChange protein
AN947_19525	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
AN947_19535	ENOG4108UUM	single-stranded DNA-binding protein
AN947_19580	ENOG4105XPH	Ferredoxin
AN947_19750	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AN947_19920	ENOG4105D07	Signal peptide peptidase, SppA
AN947_19970	ENOG4105K70	DNA-binding protein
AN947_20095	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)