locus-tag	class	description
O3Y_00005	ENOG4105QTB	Flavodoxin
O3Y_00010	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
O3Y_00015	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
O3Y_00020	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
O3Y_00025	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
O3Y_00040	ENOG4105E5Q	amino acid AbC transporter
O3Y_00045	ENOG4105EAB	amino acid AbC transporter
O3Y_00050	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
O3Y_00055	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
O3Y_00060	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
O3Y_00065	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
O3Y_00080	ENOG4108ZNX	Heat shock protein
O3Y_00085	ENOG4105JKW	Valine--pyruvate aminotransferase
O3Y_00090	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
O3Y_00095	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
O3Y_00110	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
O3Y_00120	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
O3Y_00125	ENOG4105C7B	Threonine dehydratase
O3Y_00130	ENOG4105C01	Dihydroxy-acid dehydratase
O3Y_00135	ENOG4105CM2	brancheD-chain amino acid aminotransferase
O3Y_00150	ENOG4105C0P	Mg chelatase subunit ChlI
O3Y_00155	ENOG4106HNH	Acyl-transferase
O3Y_00160	ENOG4108Z33	Thiol disulfide Interchange Protein
O3Y_00165	ENOG4105E27	serine threonine protein kinase
O3Y_00175	ENOG4105PC1	Conserved Protein
O3Y_00180	ENOG4108N23	SpoOM-related protein
O3Y_00185	ENOG4108UT2	hemolysin iii
O3Y_00195	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
O3Y_00200	ENOG4105C1A	potassium transporter peripheral membrane
O3Y_00205	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
O3Y_00210	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
O3Y_00215	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
O3Y_00220	ENOG4108WZM	domain protein
O3Y_00225	ENOG4105C79	DNA protecting protein DprA
O3Y_00230	ENOG4108RPN	Protein smg homolog
O3Y_00235	ENOG4108WI1	Dna topoisomerase
O3Y_00240	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
O3Y_00245	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
O3Y_00250	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
O3Y_00255	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
O3Y_00260	ENOG4105E2X	shikimate dehydrogenase
O3Y_00270	ENOG4108Z0R	Transferase
O3Y_00280	ENOG4105WMR	Protein CrcB homolog
O3Y_00285	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
O3Y_00295	ENOG4105D06	uba thif-type nad fad binding protein
O3Y_00300	ENOG4105WHD	thiamine biosynthesis protein ThiS
O3Y_00305	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
O3Y_00310	ENOG4105D41	biosynthesis protein thiH
O3Y_00315	ENOG4105DC7	peptidase M24
O3Y_00315	ENOG4105DC7	peptidase M24
O3Y_00325	ENOG4105CNH	Multidrug resistance protein MdtL
O3Y_00335	ENOG4108VVK	transcriptional Regulator, AsnC
O3Y_00340	ENOG4105BZU	Histidine kinase
O3Y_00345	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
O3Y_00355	ENOG4105EMK	carboxylate amino acid amine transporter
O3Y_00360	ENOG4108M6U	Universal stress protein A
O3Y_00365	ENOG41090A1	ferritin
O3Y_00370	ENOG4108V6B	universal stress protein B
O3Y_00375	ENOG4105CBX	hi0933 family
O3Y_00385	ENOG4105CGY	Dna recombination protein
O3Y_00390	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
O3Y_00395	ENOG4105JC1	sterol-binding domain protein
O3Y_00400	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
O3Y_00405	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
O3Y_00410	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
O3Y_00415	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
O3Y_00420	ENOG4105CA0	peroxidase
O3Y_00425	ENOG4107R73	Mate efflux family protein
O3Y_00435	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
O3Y_00440	ENOG4105E55	glycerol-3-phosphate acyltransferase
O3Y_00445	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
O3Y_00450	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
O3Y_00455	ENOG4105X6C	Flagellar basal body-associated protein FliL
O3Y_00460	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_00470	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
O3Y_00475	ENOG4105F8V	Hydrolase, tatD family
O3Y_00480	ENOG4105D52	delta-aminolevulinic acid dehydratase
O3Y_00490	ENOG4105C2M	dna polymerase I
O3Y_00495	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
O3Y_00500	ENOG4106RE7	Cytochrome
O3Y_00510	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
O3Y_00515	ENOG4105XCT	Protein of unknown function (DUF2489)
O3Y_00520	ENOG4105D4P	Coproporphyrinogen iii oxidase
O3Y_00525	ENOG410601J	HemY protein
O3Y_00530	ENOG4105ECF	c-methyltransferase
O3Y_00535	ENOG41076E6	Uroporphyrinogen-III Synthase
O3Y_00540	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
O3Y_00545	ENOG4107T0K	Adenylate cyclase
O3Y_00550	ENOG4105XQ6	frataxin-like protein
O3Y_00560	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
O3Y_00565	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
O3Y_00570	ENOG4105CT0	Protein of unknown function, DUF484
O3Y_00575	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
O3Y_00580	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
O3Y_00585	ENOG4105BZU	Histidine kinase
O3Y_00600	ENOG4105DQF	Hydrolase
O3Y_00605	ENOG4108EUD	Lysophospholipase
O3Y_00610	ENOG410829K	Lysine exporter protein (Lyse ygga)
O3Y_00615	ENOG4105D58	Diguanylate phosphodiesterase
O3Y_00620	ENOG4108RMU	ferritin dps family protein
O3Y_00655	ENOG4106H78	methyltransferase
O3Y_00660	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
O3Y_00665	ENOG4105CAK	Cell division ATP-binding protein ftsE
O3Y_00670	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
O3Y_00675	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
O3Y_00680	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
O3Y_00695	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
O3Y_00700	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
O3Y_00705	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
O3Y_00710	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
O3Y_00720	ENOG4105EMY	transcriptional regulator
O3Y_00725	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
O3Y_00730	ENOG4105W0Z	cytoplasmic protein
O3Y_00735	ENOG4105BZS	acriflavin resistance protein
O3Y_00740	ENOG410624X	efflux transporter, rnd family, mfp subunit
O3Y_00745	ENOG4105Y7M	Transcriptional regulator, TetR family
O3Y_00750	ENOG4105C4R	Atp-dependent dna helicase
O3Y_00755	ENOG4105MPD	Cytochrome
O3Y_00770	ENOG4105DEF	Extracellular solute-binding protein, family 5
O3Y_00775	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
O3Y_00780	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
O3Y_00790	ENOG4108UK2	deaminase
O3Y_00820	ENOG4108ZXE	
O3Y_00855	ENOG4105DC8	reductase
O3Y_00860	ENOG4105D6S	protein involved in catabolism of external DNA
O3Y_00865	ENOG4105DGW	oligopeptidase A
O3Y_00870	ENOG4105C4R	Atp-dependent dna helicase
O3Y_00880	ENOG4108DMH	HTH_ARAC
O3Y_00890	ENOG4105FR1	rard protein
O3Y_00895	ENOG4105C9U	ATP-dependent DNA helicase RecQ
O3Y_00910	ENOG4105BZ1	(ABC) transporter
O3Y_00915	ENOG4105E0K	tonB-dependent siderophore receptor
O3Y_00920	ENOG4105E0A	ABC, transporter
O3Y_00925	ENOG4105J76	Periplasmic binding protein
O3Y_00930	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
O3Y_00935	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
O3Y_00940	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
O3Y_00945	ENOG4105C5Y	PTS System
O3Y_00955	ENOG4105DSJ	YicC domain protein
O3Y_00960	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
O3Y_00965	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
O3Y_00970	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
O3Y_00975	ENOG4105D1S	lipid A biosynthesis
O3Y_00980	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
O3Y_00985	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
O3Y_00990	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_01000	ENOG4105KDC	50s ribosomal protein l28
O3Y_01005	ENOG4105W0E	50S ribosomal protein L33
O3Y_01015	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
O3Y_01020	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
O3Y_01025	ENOG4105M5K	heptosyltransferase
O3Y_01030	ENOG4106WTF	Glycosyl transferase, family 2
O3Y_01035	ENOG4105DKP	glycosyl transferase, family 9
O3Y_01040	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
O3Y_01070	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
O3Y_01075	ENOG4108ST3	glycosyltransferase
O3Y_01085	ENOG4105XA0	heptosyltransferase ii
O3Y_01100	ENOG4107T94	Endo-14-beta-xylanase
O3Y_01105	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
O3Y_01110	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
O3Y_01115	ENOG4107QKV	phosphomannomutase
O3Y_01120	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
O3Y_01125	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
O3Y_01140	ENOG4105EY8	ABC transporter
O3Y_01150	ENOG4105CEY	Amp-dependent synthetase and ligase
O3Y_01155	ENOG4108EKI	Dehydrogenase
O3Y_01165	ENOG4108UT6	Transferase hexapeptide repeat containing protein
O3Y_01225	ENOG4105D3Q	Sugar transferase
O3Y_01230	ENOG4105CY0	Metallo-Beta-Lactamase
O3Y_01235	ENOG4105CUY	Mechanosensitive ion channel
O3Y_01240	ENOG4108RG0	uracil-dna glycosylase
O3Y_01245	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
O3Y_01250	ENOG4105R2J	Conserved Protein
O3Y_01255	ENOG4105EIP	mannose-6-phosphate isomerase
O3Y_01260	ENOG4105DKQ	ROK family
O3Y_01270	ENOG4105K70	DNA-binding protein
O3Y_01280	ENOG4105C12	Phosphoribosylglycinamide synthetase
O3Y_01285	ENOG4105DC1	bifunctional purine biosynthesis protein purh
O3Y_01290	ENOG4105W1Y	Transcriptional regulator
O3Y_01295	ENOG4108M3R	transcriptional activator CadC
O3Y_01300	ENOG4105D5Q	Arginine ornithine antiporter
O3Y_01305	ENOG4105CXN	decarboxylase
O3Y_01310	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_01325	ENOG4105E0K	tonB-dependent siderophore receptor
O3Y_01330	ENOG4108UHU	Aldolase
O3Y_01335	ENOG4105C6Z	Gluconate
O3Y_01340	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
O3Y_01345	ENOG4105C01	Dihydroxy-acid dehydratase
O3Y_01350	ENOG4105DIQ	Transcriptional regulator
O3Y_01355	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
O3Y_01360	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
O3Y_01365	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
O3Y_01370	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
O3Y_01375	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
O3Y_01380	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
O3Y_01385	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
O3Y_01400	ENOG4105D8G	Major Facilitator superfamily
O3Y_01405	ENOG4105BZU	Histidine kinase
O3Y_01410	ENOG4105C9X	ppx gppa phosphatase
O3Y_01415	ENOG4105C1J	atp-dependent rna helicase
O3Y_01420	ENOG4105K63	Thioredoxin
O3Y_01425	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
O3Y_01435	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
O3Y_01445	ENOG4107QK7	reductase
O3Y_01450	ENOG4105JIM	Phosphatidylserine synthase
O3Y_01460	ENOG4105D4A	Cell wall formation (By similarity)
O3Y_01465	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
O3Y_01470	ENOG4105CS9	pantothenic acid kinase
O3Y_01475	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
O3Y_01480	ENOG4105PM1	preprotein translocase subunit SecE
O3Y_01485	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
O3Y_01490	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
O3Y_01495	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
O3Y_01500	ENOG4108VZM	50s ribosomal protein L10
O3Y_01505	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
O3Y_01510	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
O3Y_01515	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
O3Y_01520	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
O3Y_01525	ENOG4105E09	nadh pyrophosphatase
O3Y_01530	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
O3Y_01535	ENOG41062JF	Transcriptional regulator
O3Y_01545	ENOG41063SB	peptidase
O3Y_01550	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
O3Y_01560	ENOG4105C8P	)-transporter
O3Y_01565	ENOG4105DJ4	phosphatidylserine decarboxylase
O3Y_01570	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
O3Y_01575	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
O3Y_01580	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
O3Y_01585	ENOG4105K8N	protein family UPF0079, ATPase
O3Y_01590	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
O3Y_01595	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
O3Y_01600	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
O3Y_01605	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
O3Y_01610	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
O3Y_01615	ENOG4107QJR	hflk protein
O3Y_01620	ENOG4105EPW	hflc protein
O3Y_01630	ENOG41069P5	Protein slyX homolog
O3Y_01640	ENOG4108V1T	peptidylprolyl cis-trans isomerase
O3Y_01645	ENOG4105WWK	YheO domain protein
O3Y_01650	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
O3Y_01655	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
O3Y_01665	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
O3Y_01670	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
O3Y_01675	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
O3Y_01680	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
O3Y_01685	ENOG4105W53	bacterioferritin-associated ferredoxin
O3Y_01690	ENOG4108UQY	Iron-storage protein
O3Y_01695	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
O3Y_01700	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
O3Y_01705	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
O3Y_01710	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
O3Y_01720	ENOG4105CDU	Replicative dna helicase
O3Y_01725	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
O3Y_01730	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
O3Y_01735	ENOG4107QP8	phosphohexose isomerase
O3Y_01750	ENOG4105MYN	Zinc uptake regulation protein
O3Y_01755	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
O3Y_01760	ENOG4105P4Z	Phage shock protein G
O3Y_01775	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
O3Y_01780	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
O3Y_01785	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
O3Y_01790	ENOG4105EEQ	Na H antiporter
O3Y_01795	ENOG4105C3R	Methionine synthase
O3Y_01800	ENOG4105CFH	Aspartokinase
O3Y_01805	ENOG4105C5R	Aminotransferase
O3Y_01815	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
O3Y_01820	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
O3Y_01825	ENOG41086KC	Transcriptional regulator
O3Y_01830	ENOG4108UUM	single-stranded DNA-binding protein
O3Y_01835	ENOG41062P1	Diguanylate cyclase phosphodiesterase
O3Y_01855	ENOG4105E4G	Type IV pilus
O3Y_01870	ENOG4107QHF	type ii secretion system protein e
O3Y_01875	ENOG4105D7Q	type ii secretion system
O3Y_01885	ENOG4105X0D	Fimbrial protein
O3Y_01920	ENOG4105DFF	Rod shape-determining protein mreb
O3Y_01925	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
O3Y_01930	ENOG4105VQ7	Rod shape-determining protein MreD
O3Y_01935	ENOG4108Z03	MAF-like protein
O3Y_01940	ENOG4105C03	ribonuclease
O3Y_01945	ENOG4105QD6	exported protein
O3Y_01955	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
O3Y_01960	ENOG4105CEU	Arginine dihydrolase
O3Y_01980	ENOG41081QV	Universal stress protein
O3Y_01995	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
O3Y_02000	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
O3Y_02005	ENOG4105D5Q	Arginine ornithine antiporter
O3Y_02010	ENOG4105EAH	synthase
O3Y_02015	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
O3Y_02020	ENOG4105K46	50S ribosomal protein l27
O3Y_02025	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
O3Y_02030	ENOG4105DWK	Membrane
O3Y_02035	ENOG4107XM3	UPF0442 protein
O3Y_02045	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
O3Y_02050	ENOG4105NWN	ApaG protein
O3Y_02055	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
O3Y_02060	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
O3Y_02065	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
O3Y_02070	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
O3Y_02075	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
O3Y_02085	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
O3Y_02090	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
O3Y_02095	ENOG4105CEN	a g-specific adenine glycosylase
O3Y_02100	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
O3Y_02105	ENOG4105CSV	Glutaminase
O3Y_02110	ENOG4105CSA	Coproporphyrinogen iii oxidase
O3Y_02115	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
O3Y_02125	ENOG4105VZ9	UPF0235 protein
O3Y_02130	ENOG4108VIA	integral membrane protein
O3Y_02135	ENOG4105II7	pyrroline-5-carboxylate reductase
O3Y_02140	ENOG4105DFA	alanine racemase domain protein
O3Y_02145	ENOG4105CZX	twitching motility protein
O3Y_02150	ENOG4105CZX	twitching motility protein
O3Y_02160	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
O3Y_02165	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
O3Y_02170	ENOG4108UJU	UPF0301 protein
O3Y_02175	ENOG4105D7Z	glutathione synthase
O3Y_02180	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
O3Y_02185	ENOG4105RWS	endonuclease I
O3Y_02190	ENOG4105GPY	SprT protein
O3Y_02195	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
O3Y_02205	ENOG4105CV1	Transketolase (EC 2.2.1.1)
O3Y_02210	ENOG4108R4R	Iron-regulated virulence regulatory protein
O3Y_02215	ENOG4105D05	Receptor
O3Y_02220	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
O3Y_02225	ENOG4105BZA	Phosphoglycerate kinase
O3Y_02230	ENOG4105D2N	Aldolase
O3Y_02240	ENOG4105D64	Mechanosensitive ion channel
O3Y_02245	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
O3Y_02250	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
O3Y_02255	ENOG4105MPN	Membrane
O3Y_02260	ENOG4105CA9	Pyruvate kinase
O3Y_02265	ENOG410804X	Transcriptional regulator
O3Y_02270	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
O3Y_02275	ENOG4105CH5	extracellular solute-binding protein, family 7
O3Y_02330	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
O3Y_02370	ENOG4105DR5	peptidase
O3Y_02400	ENOG4108YGG	dna repair protein
O3Y_02430	ENOG4105DFP	Integrase
O3Y_02435	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
O3Y_02440	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
O3Y_02445	ENOG4105KTH	gatB Yqey
O3Y_02450	ENOG4105VCC	30S ribosomal protein S21
O3Y_02455	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
O3Y_02465	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
O3Y_02475	ENOG4107ZVW	dihydroneopterin aldolase
O3Y_02480	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
O3Y_02485	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
O3Y_02495	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
O3Y_02500	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
O3Y_02505	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
O3Y_02510	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
O3Y_02515	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
O3Y_02520	ENOG4108K5P	(LipO)protein
O3Y_02525	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
O3Y_02530	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
O3Y_02535	ENOG4105C6T	cysteine synthase
O3Y_02540	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
O3Y_02545	ENOG4108I5D	sulfate abc transporter
O3Y_02550	ENOG4105ECW	sulfate abc transporter
O3Y_02555	ENOG4108IJ6	ABC transporter
O3Y_02565	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
O3Y_02570	ENOG4105Y3E	Modulates RecA activity (By similarity)
O3Y_02575	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
O3Y_02580	ENOG4105CFH	Aspartokinase
O3Y_02585	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
O3Y_02595	ENOG4107QSA	Oxaloacetate decarboxylase
O3Y_02600	ENOG4105D9Q	decarboxylase (Beta subunit)
O3Y_02610	ENOG4105W39	Membrane
O3Y_02620	ENOG4105D9M	gamma-glutamylcysteine synthetase
O3Y_02625	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
O3Y_02630	ENOG4108JU6	CBS domain protein
O3Y_02635	ENOG4106KVJ	cytochrome C assembly protein
O3Y_02640	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
O3Y_02645	ENOG4105K5M	30s ribosomal protein S16
O3Y_02650	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
O3Y_02655	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
O3Y_02660	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
O3Y_02665	ENOG4105C0H	protease
O3Y_02670	ENOG4105C0H	protease
O3Y_02680	ENOG4105D6Z	AFG1 family ATPase
O3Y_02685	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
O3Y_02690	ENOG4108UJD	30S ribosomal protein S9
O3Y_02695	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
O3Y_02700	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
O3Y_02705	ENOG4105EIX	cytochrome c1
O3Y_02710	ENOG4107MKT	Stringent starvation protein a
O3Y_02715	ENOG4105KB2	stringent starvation protein b
O3Y_02720	ENOG4105W4M	Transport-associated protein
O3Y_02725	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
O3Y_02730	ENOG41082RQ	UPF0102 protein
O3Y_02735	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
O3Y_02740	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
O3Y_02745	ENOG4105DA5	(ABC) transporter
O3Y_02750	ENOG4105E3A	(ABC) transporter
O3Y_02755	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
O3Y_02760	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
O3Y_02765	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
O3Y_02770	ENOG4105DJ0	Poly(A) Polymerase
O3Y_02775	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
O3Y_02780	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
O3Y_02785	ENOG4105PW4	Sugar fermentation stimulation protein homolog
O3Y_02795	ENOG4105CQ7	ATP-dependent helicase
O3Y_02800	ENOG4105BZ4	penicillin-binding protein
O3Y_02805	ENOG4105D78	K07001 NTE family protein
O3Y_02810	ENOG4107QIJ	Aconitate hydratase 2
O3Y_02815	ENOG4105XTV	UPF0231 protein
O3Y_02820	ENOG4108YZA	Nitrogen regulatory protein pii
O3Y_02840	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
O3Y_02850	ENOG4105E2V	Glycosyltransferase 36
O3Y_02855	ENOG4105E2D	ec 3.2.1.52
O3Y_02860	ENOG4105RD7	BadF BadG BcrA BcrD
O3Y_02870	ENOG4108JQ7	(ABC) transporter
O3Y_02875	ENOG4105C3U	ABC transporter
O3Y_02880	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
O3Y_02890	ENOG4107QRA	Extracellular solute-binding protein, family 5
O3Y_02895	ENOG4105BZU	Histidine kinase
O3Y_02900	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
O3Y_02905	ENOG4105IPI	Membrane
O3Y_02910	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
O3Y_02920	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
O3Y_02935	ENOG4105DR5	peptidase
O3Y_02940	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
O3Y_02945	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
O3Y_02950	ENOG4105FCK	Membrane
O3Y_02955	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
O3Y_02960	ENOG4105HBR	Rna-binding protein
O3Y_02965	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
O3Y_02970	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
O3Y_02975	ENOG4105EEI	dihydropteroate synthase
O3Y_02980	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
O3Y_02990	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
O3Y_02995	ENOG4105CHV	Transcription elongation factor NusA
O3Y_03000	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
O3Y_03005	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
O3Y_03010	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
O3Y_03015	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
O3Y_03020	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
O3Y_03025	ENOG4105RT1	May be involved in cell division (By similarity)
O3Y_03040	ENOG4106RZ4	Peptidase U32
O3Y_03045	ENOG4105CFP	Peptidase U32
O3Y_03050	ENOG4105BZU	Histidine kinase
O3Y_03055	ENOG4105XPQ	lipid carrier protein
O3Y_03060	ENOG4108YYD	acetyltransferase
O3Y_03075	ENOG4105BZU	Histidine kinase
O3Y_03080	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
O3Y_03085	ENOG4105C1J	atp-dependent rna helicase
O3Y_03090	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
O3Y_03095	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
O3Y_03100	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
O3Y_03105	ENOG4105CRK	lysyL-tRNA synthetase
O3Y_03110	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
O3Y_03120	ENOG4105CPC	Aldo Keto reductase
O3Y_03125	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
O3Y_03135	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
O3Y_03140	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
O3Y_03145	ENOG4105HF0	Membrane
O3Y_03150	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
O3Y_03155	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
O3Y_03165	ENOG41063Z6	transcriptional regulator, lysR family
O3Y_03170	ENOG41080HT	Transcriptional regulator, arsr family
O3Y_03175	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
O3Y_03180	ENOG4105CJR	Integral membrane protein (MviN
O3Y_03185	ENOG4105DTN	riboflavin biosynthesis protein ribF
O3Y_03190	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
O3Y_03195	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
O3Y_03200	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
O3Y_03205	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
O3Y_03225	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
O3Y_03230	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
O3Y_03235	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
O3Y_03240	ENOG4108NEV	two component transcriptional regulator, LytTR family
O3Y_03245	ENOG4108HRK	Histidine kinase
O3Y_03250	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
O3Y_03265	ENOG4105C5H	ABC transporter
O3Y_03270	ENOG4107SC1	transglycosylase
O3Y_03275	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
O3Y_03280	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
O3Y_03285	ENOG4108K0B	C-di-gmp phosphodiesterase
O3Y_03290	ENOG4107XW0	Spermidine putrescine ABC transporter periplasmic spermidine putrescine-binding protein
O3Y_03300	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
O3Y_03305	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
O3Y_03310	ENOG4105C34	Pseudouridine synthase
O3Y_03315	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
O3Y_03320	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
O3Y_03335	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
O3Y_03340	ENOG4105CFP	Peptidase U32
O3Y_03345	ENOG4105DH7	May be involved in recombination (By similarity)
O3Y_03350	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
O3Y_03355	ENOG4105BZU	Histidine kinase
O3Y_03365	ENOG4105C9X	ppx gppa phosphatase
O3Y_03380	ENOG4105C8U	phosphate abc transporter
O3Y_03385	ENOG4105E2Z	phosphate ABC transporter (Permease
O3Y_03390	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
O3Y_03400	ENOG4105CSR	polyphosphate kinase 2
O3Y_03405	ENOG4106N3A	copper homeostasis protein cutc
O3Y_03410	ENOG4105D3R	alkyl hydroperoxide reductase
O3Y_03415	ENOG4105C5Q	Transcriptional regulator
O3Y_03420	ENOG4107QP3	malate synthase g
O3Y_03425	ENOG4108I9X	Isocitrate lyase
O3Y_03430	ENOG4105W87	Cbs domain
O3Y_03435	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
O3Y_03440	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
O3Y_03445	ENOG4105VIE	preprotein translocase, subunit YajC
O3Y_03450	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
O3Y_03455	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
O3Y_03460	ENOG4105ECY	inositol monophosphatase
O3Y_03465	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
O3Y_03470	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
O3Y_03475	ENOG4105C3J	Cysteine desulfurase
O3Y_03480	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
O3Y_03485	ENOG4108Z4V	iron-sulfur cluster assembly
O3Y_03490	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
O3Y_03495	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
O3Y_03500	ENOG4108ZIT	Ferredoxin, 2FE-2S
O3Y_03505	ENOG4105WVQ	Fe-S assembly protein IscX
O3Y_03510	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
O3Y_03515	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
O3Y_03520	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
O3Y_03530	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
O3Y_03535	ENOG4105CUT	histidyl-tRNA synthetase
O3Y_03540	ENOG4105N21	Membrane
O3Y_03545	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
O3Y_03550	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
O3Y_03565	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
O3Y_03570	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
O3Y_03575	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
O3Y_03585	ENOG4106HK8	GPR1 FUN34 yaaH family protein
O3Y_03590	ENOG4105WQI	isochorismatase
O3Y_03595	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
O3Y_03600	ENOG4105E4F	Isochorismate synthase
O3Y_03605	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
O3Y_03615	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
O3Y_03620	ENOG4105DQ5	transport system permease protein
O3Y_03625	ENOG4105TVJ	transport system, permease
O3Y_03630	ENOG4105E0A	ABC, transporter
O3Y_03640	ENOG41064T2	transcriptional regulator, lysR family
O3Y_03645	ENOG4105EUZ	Beta-lactamase domain protein
O3Y_03650	ENOG4105BZG	amino acid carrier protein
O3Y_03655	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
O3Y_03675	ENOG4106YYS	transcriptional regulatory protein
O3Y_03680	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
O3Y_03685	ENOG4105D9Q	decarboxylase (Beta subunit)
O3Y_03690	ENOG4107QSA	Oxaloacetate decarboxylase
O3Y_03705	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
O3Y_03710	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
O3Y_03715	ENOG4105CI0	Citrate lyase
O3Y_03720	ENOG4105CHY	citrate lyase, alpha
O3Y_03725	ENOG4105YGP	holo-ACP synthase CitX
O3Y_03730	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
O3Y_03745	ENOG4108Z4U	Ferredoxin
O3Y_03750	ENOG4105DZ0	fad dependent oxidoreductase
O3Y_03810	ENOG4105C26	Dehydrogenase
O3Y_03830	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
O3Y_03835	ENOG4107RK6	Methyl-accepting chemotaxis
O3Y_03850	ENOG4105XB6	Toxin coregulated pilin
O3Y_03865	ENOG4105GRU	toxin co-regulated pilus biosynthesis outer membrane protein C
O3Y_03885	ENOG4107QHF	type ii secretion system protein e
O3Y_03890	ENOG4108VEY	type ii secretion system
O3Y_03905	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
O3Y_03910	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_03925	ENOG4105DR5	peptidase
O3Y_03935	ENOG4105F88	accessory colonization factor AcfD
O3Y_03945	ENOG4105DFP	Integrase
O3Y_03950	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
O3Y_03955	ENOG4108Z1B	Cyclase dehydrase
O3Y_03960	ENOG4105VDB	UPF0125 protein
O3Y_03965	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
O3Y_03970	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
O3Y_03975	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
O3Y_03980	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
O3Y_03985	ENOG4105CFG	Acts as a chaperone (By similarity)
O3Y_03990	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
O3Y_04020	ENOG4105CFC	Transporter
O3Y_04025	ENOG4108Z6B	deaminase
O3Y_04035	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
O3Y_04045	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
O3Y_04050	ENOG4108RS6	transposase
O3Y_04070	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
O3Y_04075	ENOG4108R96	Methyltransferase, YaeB family
O3Y_04080	ENOG4105NRA	50s ribosomal protein l31 type b
O3Y_04090	ENOG4105CFC	Transporter
O3Y_04095	ENOG4108UPT	UPF0178 protein
O3Y_04105	ENOG4108428	Inherit from COG: -acetyltransferase
O3Y_04120	ENOG4105WP7	tRNA pseudouridine synthase C
O3Y_04125	ENOG4105DR9	pseudouridine synthase
O3Y_04130	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
O3Y_04135	ENOG4105CTB	Polyprenyl synthetase
O3Y_04145	ENOG4105E14	MotA TolQ exbB proton channel
O3Y_04150	ENOG4106VK6	Flagellar motor protein
O3Y_04155	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
O3Y_04160	ENOG4105ETT	transcriptional Regulator, LysR family
O3Y_04165	ENOG4105M08	Membrane
O3Y_04170	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
O3Y_04175	ENOG4105EWT	decarboxylase family
O3Y_04180	ENOG4105BZU	Histidine kinase
O3Y_04190	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
O3Y_04195	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
O3Y_04200	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
O3Y_04205	ENOG4105D01	(LipO)protein
O3Y_04210	ENOG4108UMI	ABC transporter, permease
O3Y_04215	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
O3Y_04220	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
O3Y_04225	ENOG4105D4X	repressor
O3Y_04230	ENOG4105C5Y	PTS System
O3Y_04235	ENOG4105CG3	alpha amylase, catalytic region
O3Y_04250	ENOG4105BZS	acriflavin resistance protein
O3Y_04255	ENOG4107ZF2	Phosphatase
O3Y_04260	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
O3Y_04270	ENOG4108UW5	maltose o-acetyltransferase
O3Y_04290	ENOG4105D7W	serine acetyltransferase
O3Y_04300	ENOG4105Q84	sucrose synthase
O3Y_04310	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
O3Y_04325	ENOG4108MA4	Peptidase M66
O3Y_04340	ENOG4105D3Q	Sugar transferase
O3Y_04350	ENOG4105DAY	polysaccharide export protein
O3Y_04355	ENOG4105D75	Capsular exopolysaccharide family
O3Y_04375	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
O3Y_04385	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
O3Y_04390	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
O3Y_04395	ENOG4108Z43	UPF0250 protein
O3Y_04400	ENOG4105DZ1	carboxypeptidase
O3Y_04405	ENOG4105K6T	rare lipoprotein A
O3Y_04410	ENOG4105CNI	cell division protein FtsW
O3Y_04415	ENOG4105CJN	penicillin-binding protein
O3Y_04420	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
O3Y_04425	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
O3Y_04430	ENOG4105DJF	DNA polymerase III, delta' subunit
O3Y_04435	ENOG4108U2H	Rare lipoprotein B
O3Y_04440	ENOG4105C8T	Leucyl-tRNA synthetase
O3Y_04445	ENOG4107PAI	alpha helical protein
O3Y_04450	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
O3Y_04455	ENOG4108JU5	Magnesium and cobalt efflux protein
O3Y_04460	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
O3Y_04465	ENOG4105C9A	Phoh family
O3Y_04470	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
O3Y_04475	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
O3Y_04480	ENOG4105C5Y	PTS System
O3Y_04490	ENOG4105KZ7	phosphocarrier protein hpr
O3Y_04495	ENOG4105C6T	cysteine synthase
O3Y_04500	ENOG4105EXN	Sulfate transport protein CysZ
O3Y_04505	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
O3Y_04510	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
O3Y_04515	ENOG41081QG	Porin Gram-negative type
O3Y_04525	ENOG4108Z6Z	Transcriptional regulator
O3Y_04530	ENOG4105G5H	Membrane
O3Y_04535	ENOG4107QX8	SPFH domain, Band 7 family protein
O3Y_04540	ENOG4107QR8	Thioredoxin
O3Y_04545	ENOG4105E1F	short-chain dehydrogenase reductase
O3Y_04550	ENOG4105ECP	epimerase
O3Y_04555	ENOG4108RE9	Phosphodiesterase
O3Y_04570	ENOG4108TU9	TRANSCRIPTIONal
O3Y_04575	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
O3Y_04580	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
O3Y_04585	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
O3Y_04590	ENOG4105DUX	Transporter
O3Y_04595	ENOG4105MDZ	Transcriptional activator rfaH
O3Y_04600	ENOG4105CAQ	asparagine synthetase
O3Y_04605	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
O3Y_04610	ENOG4105E2R	ROK family
O3Y_04615	ENOG4105CE4	GlcNAc 6-P deacetylase
O3Y_04620	ENOG4105CI1	PTS System
O3Y_04625	ENOG4105CX6	glutaminyL-tRNA synthetase
O3Y_04635	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
O3Y_04640	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
O3Y_04645	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
O3Y_04650	ENOG4108S3P	Sporulation domain protein
O3Y_04655	ENOG4105E96	Colicin v production protein
O3Y_04660	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
O3Y_04665	ENOG4105D3Y	Na H antiporter
O3Y_04670	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
O3Y_04680	ENOG4105EIY	sodium-type flagellar protein motY
O3Y_04685	ENOG4106WH9	Protein of unknown function (DUF2753)
O3Y_04690	ENOG4108UYE	Lactoylglutathione lyase
O3Y_04695	ENOG4105CSM	endonuclease III
O3Y_04700	ENOG4105DZB	Electron transport complex
O3Y_04705	ENOG4108UQQ	Electron transport complex
O3Y_04710	ENOG4105D6A	Electron transport complex
O3Y_04720	ENOG4108R3D	Electron transport complex
O3Y_04730	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
O3Y_04735	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
O3Y_04745	ENOG4105CHW	UPF0052 protein
O3Y_04750	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
O3Y_04755	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
O3Y_04760	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
O3Y_04765	ENOG4105M00	molybdopterin converting factor, subunit 1
O3Y_04770	ENOG4108ZAF	Molybdopterin
O3Y_04775	ENOG4105BZU	Histidine kinase
O3Y_04790	ENOG4108I5U	Uridine phosphorylase
O3Y_04800	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
O3Y_04805	ENOG4105D1F	ATP-binding protein
O3Y_04815	ENOG4105DBI	uridine monophosphokinase
O3Y_04820	ENOG4108GAE	asmA family
O3Y_04825	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
O3Y_04835	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
O3Y_04840	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
O3Y_04855	ENOG4105CHU	acetyl-coa acetyltransferase
O3Y_04860	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
O3Y_04865	ENOG41069NU	Nitroreductase
O3Y_04870	ENOG4105EJC	lysr family transcriptional regulator
O3Y_04875	ENOG4105I93	response regulator
O3Y_04890	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
O3Y_04895	ENOG4107QMP	dna polymerase iii subunits gamma and tau
O3Y_04900	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
O3Y_04905	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
O3Y_04910	ENOG4105KRS	Proteinase inhibitor
O3Y_04920	ENOG4105UBK	short-chain dehydrogenase reductase
O3Y_04925	ENOG4105ERU	peptidase
O3Y_04935	ENOG4108XM1	transcriptional regulator AsnC family
O3Y_04940	ENOG4105C29	acyl-CoA thioesterase
O3Y_04960	ENOG4105BZU	Histidine kinase
O3Y_04970	ENOG41082YX	Transcriptional regulator, arsr family
O3Y_04975	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
O3Y_05000	ENOG4108V1U	phospholipid-binding protein
O3Y_05020	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
O3Y_05035	ENOG4107YTP	response regulator receiver protein
O3Y_05045	ENOG4105BZU	Histidine kinase
O3Y_05050	ENOG4105BZU	Histidine kinase
O3Y_05055	ENOG4105BZU	Histidine kinase
O3Y_05060	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
O3Y_05075	ENOG4107QSI	ABC, transporter
O3Y_05080	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
O3Y_05085	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
O3Y_05090	ENOG4105C3U	ABC transporter
O3Y_05095	ENOG4108JQ7	(ABC) transporter
O3Y_05100	ENOG4105CHF	Glutathione S-transferase
O3Y_05105	ENOG4108DNC	Involved in acetate metabolism (By similarity)
O3Y_05110	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
O3Y_05115	ENOG4105PQ6	UPF0208 membrane protein
O3Y_05120	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
O3Y_05130	ENOG4105C7J	ABC transporter, permease
O3Y_05135	ENOG4108JJB	ABC transporter
O3Y_05140	ENOG4105BZU	Histidine kinase
O3Y_05145	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
O3Y_05150	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
O3Y_05160	ENOG4105D1H	recombination factor protein RarA
O3Y_05165	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
O3Y_05170	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
O3Y_05175	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
O3Y_05180	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
O3Y_05185	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
O3Y_05190	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
O3Y_05200	ENOG4105D0M	Protease HtpX homolog
O3Y_05210	ENOG4107FW0	short-chain dehydrogenase reductase
O3Y_05225	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
O3Y_05235	ENOG4105RHG	
O3Y_05245	ENOG4107QTF	adenylosuccinate lyase
O3Y_05250	ENOG41075W9	High frequency lysogenization protein HflD homolog
O3Y_05255	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
O3Y_05260	ENOG4107RE1	Inosine-guanosine kinase
O3Y_05270	ENOG4107S6Z	Na H antiporter
O3Y_05275	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
O3Y_05280	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
O3Y_05285	ENOG4105CIH	Imidazole acetol-phosphate transaminase
O3Y_05290	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
O3Y_05295	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
O3Y_05300	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
O3Y_05305	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
O3Y_05310	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
O3Y_05315	ENOG4108R99	pseudouridine synthase
O3Y_05325	ENOG4105VEQ	Cold shock protein
O3Y_05330	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
O3Y_05335	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
O3Y_05345	ENOG41090BQ	Glutaredoxin
O3Y_05350	ENOG4108EKI	Dehydrogenase
O3Y_05355	ENOG4106KNT	transcriptional regulator
O3Y_05360	ENOG4105DY8	decarboxylase
O3Y_05370	ENOG4105DWU	Membrane
O3Y_05395	ENOG4105CUX	Signal transduction histidine kinase
O3Y_05405	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
O3Y_05420	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
O3Y_05425	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
O3Y_05430	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
O3Y_05435	ENOG41081XQ	Conserved Protein
O3Y_05440	ENOG4105C9M	aspartyl-trna synthetase
O3Y_05445	ENOG4107104	thymidine kinase
O3Y_05450	ENOG4105CK2	sodium dicarboxylate symporter
O3Y_05455	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
O3Y_05460	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
O3Y_05465	ENOG4105DK0	Indole-3-glycerol phosphate synthase
O3Y_05470	ENOG4108I0Q	anthranilate phosphoribosyltransferase
O3Y_05475	ENOG4105DDQ	anthranilate synthase
O3Y_05480	ENOG4105CRQ	synthase (Component I)
O3Y_05490	ENOG4105DB7	PHP domain protein
O3Y_05495	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
O3Y_05500	ENOG4105FE9	pseudouridine synthase
O3Y_05505	ENOG4108JJ8	(ABC) transporter
O3Y_05510	ENOG4108JJ9	ABC, transporter
O3Y_05515	ENOG4105C3M	thioredoxin reductase
O3Y_05525	ENOG4105C9B	Cysteine desulfurase
O3Y_05530	ENOG4105BZU	Histidine kinase
O3Y_05535	ENOG4107GZ4	SanA protein
O3Y_05545	ENOG4107R1I	NAD-dependent malic enzyme
O3Y_05555	ENOG4105C8V	SAICAR synthetase
O3Y_05575	ENOG4108ZG0	Ompa motb domain protein
O3Y_05590	ENOG4105CQB	FAD linked oxidase domain protein
O3Y_05600	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
O3Y_05610	ENOG4105C84	Histidine ammonia-lyase
O3Y_05615	ENOG4105CGP	Urocanate hydratase
O3Y_05620	ENOG41088SP	formiminoglutamate hydrolase
O3Y_05625	ENOG4105CI2	imidazolone-5-propionate hydrolase
O3Y_05630	ENOG4105CZE	histidine utilization repressor
O3Y_05645	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
O3Y_05655	ENOG4105BZU	Histidine kinase
O3Y_05660	ENOG4105CQ2	DNA polymerase
O3Y_05665	ENOG4105WH1	Two component transcriptional regulator luxr family
O3Y_05670	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
O3Y_05680	ENOG4105BZU	Histidine kinase
O3Y_05690	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
O3Y_05695	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
O3Y_05700	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
O3Y_05715	ENOG4105FQ6	thiopurine methyltransferase
O3Y_05730	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
O3Y_05735	ENOG41067MG	lrgb family
O3Y_05745	ENOG4105CJB	Exodeoxyribonuclease I
O3Y_05750	ENOG4108ETY	sodium dicarboxylate symporter
O3Y_05755	ENOG4105E0X	reductase
O3Y_05760	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
O3Y_05765	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
O3Y_05770	ENOG4108YZT	Adenosylcobinamide kinase
O3Y_05785	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
O3Y_05790	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
O3Y_05805	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_05825	ENOG4107QK7	reductase
O3Y_05830	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
O3Y_05835	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
O3Y_05840	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
O3Y_05845	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
O3Y_05850	ENOG4105C72	UPF0176 protein
O3Y_05860	ENOG4105S8Q	sugar efflux transporter
O3Y_05870	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
O3Y_05895	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
O3Y_05900	ENOG4105EAQ	(twin-arginine translocation) pathway signal
O3Y_05905	ENOG4105C5X	domain protein
O3Y_05920	ENOG4105CH5	extracellular solute-binding protein, family 7
O3Y_05930	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
O3Y_05945	ENOG41067TZ	transcriptional regulator, MarR family
O3Y_05950	ENOG4105C94	Transporter
O3Y_05960	ENOG4105VZJ	PTS System
O3Y_05970	ENOG4105VCP	PTS System
O3Y_05975	ENOG4105F8D	glycoside hydrolase family 4
O3Y_05980	ENOG410901P	UPF0249 protein
O3Y_05985	ENOG41060NJ	transcriptional regulator
O3Y_05990	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
O3Y_05995	ENOG4105DJ9	glucan biosynthesis protein
O3Y_06000	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_06015	ENOG4105CGF	Aromatic amino acid aminotransferase
O3Y_06035	ENOG4105C5S	asparaginyl-tRNA synthetase
O3Y_06040	ENOG4108NVR	Methyl-accepting chemotaxis
O3Y_06045	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
O3Y_06050	ENOG4105EJQ	L-serine dehydratase
O3Y_06055	ENOG4105C44	Serine transporter
O3Y_06060	ENOG4105P8F	nudix hydrolase
O3Y_06065	ENOG4105CRQ	synthase (Component I)
O3Y_06080	ENOG4105CM6	amino acid regulated cytosolic protein
O3Y_06090	ENOG4108JU8	Transcriptional regulator
O3Y_06095	ENOG4105D9U	N-acetyltransferase
O3Y_06110	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
O3Y_06115	ENOG4108NVR	Methyl-accepting chemotaxis
O3Y_06120	ENOG4105C8P	)-transporter
O3Y_06125	ENOG4105BZU	Histidine kinase
O3Y_06130	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
O3Y_06135	ENOG4108MJ5	VirK protein
O3Y_06140	ENOG4105RW8	MltA-interacting MipA family protein
O3Y_06145	ENOG4105EB3	Histidine kinase
O3Y_06150	ENOG4107EXC	regulatoR
O3Y_06175	ENOG4105C2J	ABC transporter
O3Y_06180	ENOG4107SDZ	Galactoside transport system permease protein mglC
O3Y_06210	ENOG41073TP	transcriptional regulator
O3Y_06215	ENOG4105CR4	methylisocitrate lyase
O3Y_06220	ENOG4105BZN	citrate synthase
O3Y_06225	ENOG4108I0Z	Aconitate hydratase
O3Y_06230	ENOG4105C7F	AcnD-accessory protein PrpF
O3Y_06235	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
O3Y_06250	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
O3Y_06255	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
O3Y_06260	ENOG4105F1J	Homogentisate 1,2-dioxygenase
O3Y_06270	ENOG4108RXX	maleylacetoacetate isomerase
O3Y_06275	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
O3Y_06280	ENOG4105BZU	Histidine kinase
O3Y_06290	ENOG4106TD9	Diguanylate cyclase
O3Y_06295	ENOG4105DR4	Methyltransferase
O3Y_06300	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
O3Y_06305	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
O3Y_06310	ENOG4108MN8	Membrane
O3Y_06315	ENOG4105CDA	abc transporter atp-binding protein
O3Y_06320	ENOG4105DRP	amino acid AbC transporter
O3Y_06325	ENOG4105EZ7	amino acid ABC transporter
O3Y_06330	ENOG4107QXX	ABC transporter
O3Y_06340	ENOG410667J	hydrolase
O3Y_06345	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
O3Y_06350	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
O3Y_06370	ENOG4105BZU	Histidine kinase
O3Y_06380	ENOG4105BZU	Histidine kinase
O3Y_06385	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
O3Y_06390	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
O3Y_06400	ENOG4105BZU	Histidine kinase
O3Y_06420	ENOG4105CQ7	ATP-dependent helicase
O3Y_06430	ENOG4105R8A	Heat shock protein
O3Y_06435	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
O3Y_06445	ENOG4105EJC	lysr family transcriptional regulator
O3Y_06450	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
O3Y_06455	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
O3Y_06460	ENOG4105KPY	Small multidrug resistance protein
O3Y_06465	ENOG4108NVR	Methyl-accepting chemotaxis
O3Y_06470	ENOG4108VYJ	response regulator receiver protein
O3Y_06480	ENOG4105CBS	Chea signal transduction histidine kinase
O3Y_06485	ENOG4105CBS	Chea signal transduction histidine kinase
O3Y_06490	ENOG4105BZU	Histidine kinase
O3Y_06500	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
O3Y_06505	ENOG4108V3W	Chemotaxis protein, CheW
O3Y_06510	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_06515	ENOG4108N3W	hemolysin secretion protein
O3Y_06520	ENOG4107SDU	Methyl-accepting chemotaxis
O3Y_06525	ENOG4105C1J	atp-dependent rna helicase
O3Y_06535	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
O3Y_06540	ENOG4105CW7	secretion protein, HlyD family
O3Y_06545	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
O3Y_06550	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_06555	ENOG4105CTD	carboxy-peptidase
O3Y_06560	ENOG4108WC9	type VI secretion system effector, hcp1 family
O3Y_06565	ENOG4105CS6	Rhs element vgr protein
O3Y_06590	ENOG410829K	Lysine exporter protein (Lyse ygga)
O3Y_06595	ENOG4105BZG	amino acid carrier protein
O3Y_06610	ENOG4107RUE	extracellular solute-binding protein family 1
O3Y_06615	ENOG4107RUE	extracellular solute-binding protein family 1
O3Y_06620	ENOG4105D38	putrescine abc transporter
O3Y_06625	ENOG4105F38	ABC transporter, permease
O3Y_06630	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
O3Y_06650	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
O3Y_06655	ENOG4105Q9Y	Universal stress protein
O3Y_06660	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
O3Y_06675	ENOG4105C59	p-type ATPase
O3Y_06685	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
O3Y_06700	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
O3Y_06715	ENOG4105BZU	Histidine kinase
O3Y_06740	ENOG4108RC6	RTX toxin
O3Y_06745	ENOG4105EUK	rtx toxin RtxA
O3Y_06765	ENOG4105TIV	Cryptic phage CTXphi transcriptional repressor RstR
O3Y_06775	ENOG4107927	Cholera enterotoxin, A subunit
O3Y_06780	ENOG4105MQ5	zona occludens toxin
O3Y_06815	ENOG4105TIV	Cryptic phage CTXphi transcriptional repressor RstR
O3Y_06900	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
O3Y_06905	ENOG4105DAN	ATP-dependent protease
O3Y_06910	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
O3Y_06925	ENOG4105C5H	ABC transporter
O3Y_06935	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
O3Y_06940	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
O3Y_06945	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
O3Y_06950	ENOG4105C7I	Dehydrogenase
O3Y_06960	ENOG4105CD8	aminopeptidase N
O3Y_06995	ENOG4105C4X	radical SAM domain protein
O3Y_07075	ENOG4105EFC	phage portal protein HK97 family
O3Y_07250	ENOG4107TII	Recombinase
O3Y_07255	ENOG4105CD8	aminopeptidase N
O3Y_07265	ENOG4105CN1	protease
O3Y_07270	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
O3Y_07275	ENOG4108ZGC	gaf domain protein
O3Y_07280	ENOG4105BZ1	(ABC) transporter
O3Y_07285	ENOG4105H2K	paraquat-inducible protein a
O3Y_07290	ENOG4105DY2	Paraquat-inducible protein b
O3Y_07295	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
O3Y_07300	ENOG4105QNR	S1 RNA binding domain protein
O3Y_07315	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
O3Y_07325	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
O3Y_07340	ENOG4105QAX	Iron-sulfur
O3Y_07345	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
O3Y_07355	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
O3Y_07375	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
O3Y_07380	ENOG4105C5H	ABC transporter
O3Y_07385	ENOG4105BZU	Histidine kinase
O3Y_07390	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
O3Y_07400	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
O3Y_07405	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
O3Y_07410	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
O3Y_07415	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
O3Y_07440	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
O3Y_07445	ENOG4106IUH	DTW domain containing protein
O3Y_07455	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_07460	ENOG4107TT5	NLP P60 protein
O3Y_07470	ENOG4105FGM	Fructosamine kinase
O3Y_07480	ENOG4107QI1	Mate efflux family protein
O3Y_07500	ENOG41067XB	TonB family
O3Y_07505	ENOG4109015	Biopolymer transport protein exbD tolR
O3Y_07535	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
O3Y_07540	ENOG4108IJ9	(ABC) transporter
O3Y_07545	ENOG4105E98	transcriptional regulator DeoR family
O3Y_07550	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
O3Y_07555	ENOG4105XEP	YhcH YjgK YiaL family protein
O3Y_07560	ENOG4105M4H	endoribonuclease L-psp
O3Y_07565	ENOG4105DDV	Transcriptional regulator (LacI family
O3Y_07570	ENOG4105CS2	ec 3.2.1.21
O3Y_07575	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
O3Y_07590	ENOG4107QZV	Type I secretion membrane fusion protein
O3Y_07600	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
O3Y_07605	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
O3Y_07610	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
O3Y_07615	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
O3Y_07620	ENOG4105C4M	(Ubiquinol oxidase) subunit I
O3Y_07630	ENOG4105C9Q	fumarate hydratase class II
O3Y_07660	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
O3Y_07665	ENOG4105DUM	transcriptional regulator, lysR family
O3Y_07670	ENOG4108TWJ	NADH dehydrogenase subunit 5
O3Y_07680	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
O3Y_07690	ENOG4105CH6	catalase
O3Y_07705	ENOG4107FQX	Alpha-acetolactate decarboxylase
O3Y_07710	ENOG4105C7K	acetolactate synthase
O3Y_07720	ENOG4105BZU	Histidine kinase
O3Y_07725	ENOG4106TD9	Diguanylate cyclase
O3Y_07730	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
O3Y_07735	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
O3Y_07740	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
O3Y_07755	ENOG4105BZU	Histidine kinase
O3Y_07770	ENOG4107R88	Chemotaxis protein (CheV)
O3Y_07780	ENOG4106YYS	transcriptional regulatory protein
O3Y_07785	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
O3Y_07800	ENOG4107V40	secretion protein, HlyD family
O3Y_07820	ENOG4105CVG	Homoserine O-transsuccinylase
O3Y_07825	ENOG41090FY	type IV pilus biogenesis stability protein PilW
O3Y_07840	ENOG4108VKG	metal-dependent hydrolase
O3Y_07850	ENOG4105F04	LysR family Transcriptional regulator
O3Y_07875	ENOG4105DFG	type I secretion outer membrane protein
O3Y_07880	ENOG4105CDV	Ompa motb domain protein
O3Y_07885	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
O3Y_07890	ENOG4105E3Q	saccharopine dehydrogenase
O3Y_07900	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
O3Y_07915	ENOG4108I0Y	(ABC) transporter
O3Y_07920	ENOG4105UQX	Mate efflux family protein
O3Y_07925	ENOG4105CGD	Nad-dependent epimerase dehydratase
O3Y_07935	ENOG4105C2C	drug resistance transporter, Bcr CflA
O3Y_07940	ENOG4105I08	Pseudouridine synthase
O3Y_07945	ENOG4105CFI	type iii restriction protein res subunit
O3Y_07965	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
O3Y_07985	ENOG4108N3W	hemolysin secretion protein
O3Y_08015	ENOG4105KXC	Collagenase
O3Y_08025	ENOG4105BZU	Histidine kinase
O3Y_08030	ENOG4105BZU	Histidine kinase
O3Y_08035	ENOG4105CJW	magnesium transporter
O3Y_08050	ENOG4105C44	Serine transporter
O3Y_08060	ENOG4105CJ1	ABC, transporter
O3Y_08065	ENOG4107QWP	ABC-2 type transporter
O3Y_08075	ENOG4105XZD	Fe-S protein
O3Y_08085	ENOG4105VNH	ABC transporter solute-binding protein
O3Y_08090	ENOG4105CXZ	ABC transporter, permease
O3Y_08095	ENOG4108VGW	abc transporter atp-binding protein
O3Y_08100	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
O3Y_08105	ENOG4108W1A	pseudouridine synthase
O3Y_08110	ENOG4105C8J	)-transporter
O3Y_08115	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
O3Y_08120	ENOG4105C28	cystathionine
O3Y_08125	ENOG4108R3E	Dna-3-methyladenine glycosylase i
O3Y_08140	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
O3Y_08155	ENOG41087YS	Phage shock protein A
O3Y_08160	ENOG4105E51	psp operon transcriptional activator
O3Y_08165	ENOG4108J59	Extracellular solute-binding protein, family 5
O3Y_08170	ENOG4108I5W	peptide transport system, permease protein
O3Y_08175	ENOG4108EU3	peptide transport system, permease
O3Y_08180	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
O3Y_08185	ENOG4108JQ2	peptide transport system atp-binding protein
O3Y_08200	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
O3Y_08220	ENOG4107QY8	reductase
O3Y_08240	ENOG4105TMB	Formate nitrite transporter
O3Y_08250	ENOG4108535	NAD dependent epimerase/dehydratase family
O3Y_08255	ENOG4105GFG	DUF218 domain
O3Y_08265	ENOG4107835	probably involved in intracellular septation (By similarity)
O3Y_08270	ENOG4105NAU	thioesterase Superfamily protein
O3Y_08275	ENOG4105K9H	YciI-like protein
O3Y_08285	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
O3Y_08290	ENOG4105DZ2	Transcriptional regulator
O3Y_08310	ENOG4105BZU	Histidine kinase
O3Y_08315	ENOG4105CCT	upf0313 protein
O3Y_08325	ENOG4105EW9	transcriptional regulator AsnC family
O3Y_08330	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
O3Y_08335	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
O3Y_08340	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
O3Y_08345	ENOG4106371	Methyltransferase
O3Y_08350	ENOG4107S90	membrAne
O3Y_08355	ENOG4106WF9	DNA-binding transcriptional regulator TorR
O3Y_08360	ENOG4108SBI	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
O3Y_08365	ENOG4105ETE	Transcriptional regulator (LacI family
O3Y_08370	ENOG4105HP8	regulator of competence-specific genes
O3Y_08390	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
O3Y_08395	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
O3Y_08400	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
O3Y_08405	ENOG4105RKX	Protein of unknown function (DUF2498)
O3Y_08410	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
O3Y_08420	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
O3Y_08425	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
O3Y_08430	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
O3Y_08440	ENOG4107QPN	acyl-Coa dehydrogenase
O3Y_08445	ENOG41067SE	Tetr family transcriptional regulator
O3Y_08455	ENOG4105MTM	Protein of unknown function (DUF1496)
O3Y_08460	ENOG4105C26	Dehydrogenase
O3Y_08465	ENOG4108R86	Transcriptional regulator
O3Y_08490	ENOG4105F1S	paraquat-inducible protein a
O3Y_08495	ENOG4105DY2	Paraquat-inducible protein b
O3Y_08515	ENOG4105DFP	Integrase
O3Y_08520	ENOG4105DFP	Integrase
O3Y_08525	ENOG4105C0D	helicase
O3Y_08545	ENOG4105DZR	Type I site-specific deoxyribonuclease
O3Y_08565	ENOG4105CVR	type I restriction-modification system
O3Y_08585	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
O3Y_08590	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
O3Y_08595	ENOG4105QEK	Transcriptional regulator
O3Y_08605	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
O3Y_08610	ENOG41069H7	transport system small permease component
O3Y_08615	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
O3Y_08620	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
O3Y_08625	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
O3Y_08630	ENOG4105CE4	GlcNAc 6-P deacetylase
O3Y_08635	ENOG4108478	ec 3.2.1.18
O3Y_08645	ENOG4108YGG	dna repair protein
O3Y_08670	ENOG4108NYK	Tape measure protein
O3Y_08800	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
O3Y_08810	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
O3Y_08815	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
O3Y_08820	ENOG4105C26	Dehydrogenase
O3Y_08830	ENOG4105DM4	PTS System
O3Y_08835	ENOG4105DM4	PTS System
O3Y_08840	ENOG4108YRF	PTS System
O3Y_08850	ENOG4106R3P	AraC family transcriptional regulator
O3Y_08855	ENOG4105DM4	PTS System
O3Y_08860	ENOG4105EIP	mannose-6-phosphate isomerase
O3Y_08865	ENOG4108RNS	Exports L-alanine (By similarity)
O3Y_08870	ENOG4105BZU	Histidine kinase
O3Y_08880	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
O3Y_08890	ENOG4105KCK	Peptidoglycan-associated lipoprotein
O3Y_08895	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
O3Y_08905	ENOG4105M8F	Biopolymer transport protein exbD tolR
O3Y_08910	ENOG4105E02	MotA TolQ exbB proton channel
O3Y_08915	ENOG4107YD3	Thioesterase
O3Y_08920	ENOG4105KJB	cyd operon protein YbgE
O3Y_08930	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
O3Y_08935	ENOG4105C4M	(Ubiquinol oxidase) subunit I
O3Y_08940	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
O3Y_08945	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
O3Y_08950	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
O3Y_08955	ENOG4105C8N	cysteinyl-tRNA synthetase
O3Y_08960	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
O3Y_08965	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
O3Y_08970	ENOG4105D58	Diguanylate phosphodiesterase
O3Y_08985	ENOG4105ZU8	porin-like protein H
O3Y_08990	ENOG4105DVT	helicase
O3Y_08995	ENOG4105EJ9	Membrane
O3Y_09000	ENOG4108URS	primosomal replication protein n''
O3Y_09005	ENOG4106428	Protein of unknown function (DUF2496)
O3Y_09010	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_09015	ENOG4105CGK	Exodeoxyribonuclease III
O3Y_09020	ENOG4106YG3	ABC transporter
O3Y_09025	ENOG4105DSP	amino acid AbC transporter
O3Y_09030	ENOG4105E89	ABC transporter
O3Y_09035	ENOG4108JEH	abc transporter atp-binding protein
O3Y_09045	ENOG4105C6N	Formate acetyltransferase
O3Y_09055	ENOG4108N3W	hemolysin secretion protein
O3Y_09060	ENOG4105F1A	Pyruvate formate-lyase
O3Y_09070	ENOG4105XWI	UPF0304 protein
O3Y_09075	ENOG4105CYN	Serine protein kinase
O3Y_09080	ENOG4106AKX	UPF0229 protein
O3Y_09085	ENOG4105ED1	spovr family
O3Y_09090	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
O3Y_09100	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
O3Y_09105	ENOG4105BZ1	(ABC) transporter
O3Y_09110	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
O3Y_09120	ENOG4105D60	lipoprotein releasing system transmembrane protein
O3Y_09125	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
O3Y_09130	ENOG4105D60	lipoprotein releasing system transmembrane protein
O3Y_09140	ENOG4108JA2	transcriptioN-repair coupling factor
O3Y_09150	ENOG4106M3D	hemolysin
O3Y_09160	ENOG4105CEP	NADH dehydrogenase
O3Y_09190	ENOG4105K59	histidine triad (HIT) protein
O3Y_09195	ENOG4108NVR	Methyl-accepting chemotaxis
O3Y_09205	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
O3Y_09210	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
O3Y_09215	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
O3Y_09220	ENOG4105CNU	cell division protein FtsK
O3Y_09225	ENOG4105EW9	transcriptional regulator AsnC family
O3Y_09230	ENOG4105DCF	alanine dehydrogenase
O3Y_09240	ENOG4107R11	Transcriptional regulator
O3Y_09250	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
O3Y_09255	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
O3Y_09260	ENOG4105CFV	Tetratricopeptide repeat protein
O3Y_09265	ENOG4105Q4A	inner membrane protein yciS
O3Y_09270	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
O3Y_09275	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
O3Y_09280	ENOG4105CAT	Cytidine monophosphate kinase
O3Y_09285	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
O3Y_09290	ENOG4105EIN	peptidylprolyl cis-trans isomerase
O3Y_09295	ENOG4105K70	DNA-binding protein
O3Y_09300	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
O3Y_09305	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
O3Y_09310	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
O3Y_09315	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
O3Y_09325	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
O3Y_09330	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
O3Y_09335	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
O3Y_09340	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
O3Y_09345	ENOG4105CNG	UPF0061 protein
O3Y_09360	ENOG4105BZU	Histidine kinase
O3Y_09370	ENOG4108HPI	phosphatidate Cytidylyltransferase
O3Y_09400	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
O3Y_09415	ENOG4105JQN	Transcriptional regulator
O3Y_09425	ENOG4107QY8	reductase
O3Y_09430	ENOG4105CUW	cytochrome C-TYPE protein
O3Y_09435	ENOG410662T	chitinase
O3Y_09440	ENOG4105D9N	nucleoside
O3Y_09445	ENOG4105JQN	Transcriptional regulator
O3Y_09450	ENOG4105CVE	Lytic murein transglycosylase
O3Y_09455	ENOG4105VNG	YcgL domain-containing protein
O3Y_09460	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
O3Y_09465	ENOG4107QMS	site-determining protein
O3Y_09470	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
O3Y_09495	ENOG4107S74	Lysophospholipid transporter LplT
O3Y_09505	ENOG4108N3W	hemolysin secretion protein
O3Y_09510	ENOG4108JCI	Transcriptional regulator
O3Y_09515	ENOG4105DKK	Benzoate
O3Y_09520	ENOG4105CEY	Amp-dependent synthetase and ligase
O3Y_09525	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
O3Y_09530	ENOG4108IPT	Naphthoate synthase
O3Y_09535	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
O3Y_09540	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
O3Y_09545	ENOG4105E4F	Isochorismate synthase
O3Y_09550	ENOG4105CHM	Aminotransferase
O3Y_09555	ENOG4105DK2	UPF0207 protein
O3Y_09560	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
O3Y_09580	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
O3Y_09585	ENOG4105CEY	Amp-dependent synthetase and ligase
O3Y_09590	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
O3Y_09605	ENOG41072GX	Peptidase M22 Glycoprotease
O3Y_09610	ENOG4105DVT	helicase
O3Y_09620	ENOG4105CIY	formyltetrahydrofolate deformylase
O3Y_09625	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
O3Y_09630	ENOG4105D07	Signal peptide peptidase, SppA
O3Y_09635	ENOG4105HDK	L-asparaginase
O3Y_09640	ENOG4105VUT	cytoplasmic protein
O3Y_09650	ENOG4105E0X	reductase
O3Y_09655	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
O3Y_09660	ENOG4105DSB	aldose 1-epimerase
O3Y_09670	ENOG4105DHI	Methyltransferase
O3Y_09685	ENOG4107R88	Chemotaxis protein (CheV)
O3Y_09690	ENOG4105DAG	ROK family
O3Y_09695	ENOG4105CA9	Pyruvate kinase
O3Y_09700	ENOG4108NRW	Phospholipase, patatin family
O3Y_09715	ENOG4105C8J	)-transporter
O3Y_09725	ENOG4105CI1	PTS System
O3Y_09730	ENOG4105F8V	Hydrolase, tatD family
O3Y_09735	ENOG4107QRG	dna polymerase iii
O3Y_09740	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
O3Y_09745	ENOG4105HHA	aminodeoxychorismate lyase
O3Y_09750	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
O3Y_09755	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
O3Y_09760	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
O3Y_09765	ENOG4105CHR	reductase
O3Y_09770	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
O3Y_09775	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
O3Y_09780	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
O3Y_09785	ENOG4105VGS	50s ribosomal protein l32
O3Y_09790	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
O3Y_09795	ENOG4108UHJ	MAF-like protein
O3Y_09800	ENOG4105EI2	Pseudouridine synthase
O3Y_09810	ENOG4105C03	ribonuclease
O3Y_09815	ENOG4105CHH	sulfate transporter
O3Y_09825	ENOG4108EKI	Dehydrogenase
O3Y_09830	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
O3Y_09835	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
O3Y_09840	ENOG4105DFD	Na H antiporter
O3Y_09850	ENOG4106V8H	Nucleoid-associated protein
O3Y_09860	ENOG4105E68	Sulfatase
O3Y_09865	ENOG4105DGU	Histone deacetylase
O3Y_09870	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
O3Y_09875	ENOG4105M2J	Glutaredoxin
O3Y_09880	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
O3Y_09895	ENOG410903C	(LipO)protein
O3Y_09905	ENOG4105KWW	Biogenesis protein
O3Y_09910	ENOG4107QX9	Thiol disulfide interChange protein
O3Y_09915	ENOG4105DA4	cytochrome c-type biogenesis protein
O3Y_09920	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
O3Y_09925	ENOG41067VX	Heme exporter protein
O3Y_09930	ENOG41060IM	Heme exporter protein
O3Y_09935	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
O3Y_09940	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
O3Y_09950	ENOG4108V3W	Chemotaxis protein, CheW
O3Y_09960	ENOG4107QJE	Chromosome Partitioning Protein
O3Y_09965	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
O3Y_09970	ENOG4105CBS	Chea signal transduction histidine kinase
O3Y_09975	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
O3Y_09980	ENOG4108VYJ	response regulator receiver protein
O3Y_09985	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
O3Y_09990	ENOG4107R21	site-determining protein
O3Y_09995	ENOG4105FZW	flagellar biosynthesis regulator FlhF
O3Y_10000	ENOG4105D7B	Flagellar biosynthesis protein flha
O3Y_10005	ENOG4108BY2	phosphohistidine phosphatase
O3Y_10010	ENOG4108JQM	Insulinase (Peptidase family M16)
O3Y_10020	ENOG4105C75	arginyL-tRNA synthetase
O3Y_10040	ENOG4105XFK	Ferrous iron transport protein A
O3Y_10045	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
O3Y_10050	ENOG4105NXV	High-affinity zinc uptake system protein
O3Y_10055	ENOG4105FDK	ABC transporter
O3Y_10060	ENOG4105FAV	ABC, transporter
O3Y_10065	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
O3Y_10070	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
O3Y_10075	ENOG4105C7S	Dehydrogenase
O3Y_10080	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
O3Y_10085	ENOG4105E33	succinate dehydrogenase
O3Y_10090	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
O3Y_10095	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
O3Y_10100	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
O3Y_10105	ENOG4105BZN	citrate synthase
O3Y_10110	ENOG4107QNR	UPF0135 protein
O3Y_10120	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
O3Y_10125	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
O3Y_10130	ENOG4105EV9	Alpha Beta Hydrolase
O3Y_10140	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
O3Y_10145	ENOG41067MG	lrgb family
O3Y_10150	ENOG4105VAW	lrga family
O3Y_10155	ENOG4105CMU	LysR family (Transcriptional regulator
O3Y_10165	ENOG41090R7	Ferric uptake
O3Y_10170	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
O3Y_10175	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
O3Y_10180	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
O3Y_10185	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
O3Y_10190	ENOG4105Q8W	reductase
O3Y_10195	ENOG4105MH2	YfcL protein
O3Y_10200	ENOG4108BPE	-transporting atpase
O3Y_10205	ENOG4105EN6	Membrane
O3Y_10210	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
O3Y_10215	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
O3Y_10225	ENOG4105D00	flagellar biosynthetic protein flhB
O3Y_10230	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
O3Y_10235	ENOG4105VS8	Flagellar biosynthetic protein fliq
O3Y_10240	ENOG4105CN7	Flagellar biosynthetic protein FliP
O3Y_10245	ENOG4105VTB	flagellar biosynthesis protein fliO
O3Y_10250	ENOG4105DD5	Flagellar motor switch protein
O3Y_10255	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
O3Y_10260	ENOG4105X6C	Flagellar basal body-associated protein FliL
O3Y_10275	ENOG4108JIR	Flagellum-specific ATP synthase
O3Y_10280	ENOG4105W2B	Flagellar assembly protein
O3Y_10285	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
O3Y_10290	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
O3Y_10295	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
O3Y_10300	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
O3Y_10305	ENOG4105BZU	Histidine kinase
O3Y_10310	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
O3Y_10315	ENOG4105MQ3	flagellar protein FliS
O3Y_10325	ENOG4107W9T	flagellar hook-associated
O3Y_10330	ENOG41063QE	flagellar protein FlaG
O3Y_10335	ENOG4105I03	Flagellin
O3Y_10340	ENOG4105I03	Flagellin
O3Y_10345	ENOG4105I03	Flagellin
O3Y_10350	ENOG4105EZR	dyp-type peroxidase family protein
O3Y_10355	ENOG4105QZU	Inner membrane protein YfeZ
O3Y_10370	ENOG4105KUZ	arsenate reductase
O3Y_10375	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
O3Y_10390	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
O3Y_10395	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
O3Y_10405	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
O3Y_10410	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_10425	ENOG4105ERG	peptidase m48, ste24p
O3Y_10430	ENOG4105K89	arsenate reductase
O3Y_10435	ENOG4105CS1	NAD(P)H quinone oxidoreductase
O3Y_10450	ENOG4105C2W	permease
O3Y_10455	ENOG4108Z66	YbaK ebsC protein
O3Y_10460	ENOG4105CGH	5'-nucleotidase
O3Y_10465	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
O3Y_10470	ENOG41063JG	Transcriptional regulator
O3Y_10475	ENOG4108YY7	Invasion gene expression up-regulator SirB
O3Y_10480	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
O3Y_10485	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
O3Y_10490	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
O3Y_10495	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
O3Y_10500	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
O3Y_10505	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
O3Y_10510	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
O3Y_10515	ENOG4105C3G	gtp-binding protein
O3Y_10530	ENOG4105I03	Flagellin
O3Y_10535	ENOG4105I03	Flagellin
O3Y_10550	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
O3Y_10555	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
O3Y_10560	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
O3Y_10565	ENOG4105CGA	flagellar basal-body rod protein FlgG
O3Y_10570	ENOG4108KPB	Flagellar basal-body rod protein FlgF
O3Y_10575	ENOG4105BZE	flagellar hook protein, FlgE
O3Y_10580	ENOG4105W00	Flagellar hook capping protein
O3Y_10585	ENOG4108ZC9	flagellar basal-body rod protein flgc
O3Y_10590	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
O3Y_10595	ENOG4105BZU	Histidine kinase
O3Y_10600	ENOG4107R88	Chemotaxis protein (CheV)
O3Y_10635	ENOG4105C0W	non-ribosomal peptide synthetase
O3Y_10640	ENOG4105Q26	Siderophore-interacting protein
O3Y_10645	ENOG4107RBR	Receptor
O3Y_10655	ENOG4105UYK	outer membrane protein a
O3Y_10660	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
O3Y_10665	ENOG4105C59	p-type ATPase
O3Y_10675	ENOG4105E2D	ec 3.2.1.52
O3Y_10680	ENOG4105MBR	gumn family
O3Y_10690	ENOG4108DG9	Smr protein MutS2
O3Y_10695	ENOG4105FE9	pseudouridine synthase
O3Y_10700	ENOG4105BZU	Histidine kinase
O3Y_10705	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
O3Y_10710	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
O3Y_10715	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
O3Y_10720	ENOG4105E7A	Glutamine amidotransferase
O3Y_10725	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
O3Y_10745	ENOG4108JDX	DNA polymerase iii, epsilon subunit
O3Y_10750	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
O3Y_10755	ENOG4105D1A	Methyltransferase
O3Y_10760	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
O3Y_10765	ENOG4105E9H	Lytic Murein transglycosylase
O3Y_10775	ENOG4108YZA	Nitrogen regulatory protein pii
O3Y_10780	ENOG4105PY6	Phenolic acid decarboxylase
O3Y_10785	ENOG4105N7H	Cytochrome
O3Y_10790	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
O3Y_10795	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
O3Y_10800	ENOG4105C0B	DNA polymerase III (alpha subunit)
O3Y_10805	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
O3Y_10810	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
O3Y_10815	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
O3Y_10820	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
O3Y_10825	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
O3Y_10830	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
O3Y_10840	ENOG4105DZP	Membrane-associated zinc metalloprotease
O3Y_10845	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
O3Y_10850	ENOG4105KNE	Phosphatidate cytidylyltransferase
O3Y_10855	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
O3Y_10860	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
O3Y_10865	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
O3Y_10870	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
O3Y_10875	ENOG4105CE9	30S ribosomal protein S2
O3Y_10880	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
O3Y_10885	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
O3Y_10890	ENOG4108T8E	UPF0325 protein
O3Y_10895	ENOG4108ZAI	phosphatidylglycerophosphatase a
O3Y_10900	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
O3Y_10905	ENOG4107YIM	Involved in the transcription termination process (By similarity)
O3Y_10910	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
O3Y_10925	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
O3Y_10930	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
O3Y_10935	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
O3Y_10940	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
O3Y_10945	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
O3Y_10955	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
O3Y_10960	ENOG4105C7N	Xanthine uracil vitamin C permease
O3Y_10965	ENOG4105CIN	aminoacyl-histidine dipeptidase
O3Y_10970	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
O3Y_10975	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
O3Y_10985	ENOG4105C8J	)-transporter
O3Y_10990	ENOG4105BZU	Histidine kinase
O3Y_11000	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
O3Y_11010	ENOG4105CJ2	(LipO)protein
O3Y_11015	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
O3Y_11020	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
O3Y_11025	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
O3Y_11030	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
O3Y_11035	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
O3Y_11040	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
O3Y_11045	ENOG4105M85	Bola protein
O3Y_11050	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
O3Y_11060	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
O3Y_11065	ENOG4105EYM	Major Facilitator superfamily
O3Y_11075	ENOG4105K6V	RNA polymerase
O3Y_11085	ENOG4105DRB	nucleoside-specific channel-forming protein
O3Y_11090	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
O3Y_11095	ENOG4107S0N	DJ-1 family
O3Y_11100	ENOG4105C9B	Cysteine desulfurase
O3Y_11105	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
O3Y_11110	ENOG4105CUZ	uba thif-type nad fad binding protein
O3Y_11115	ENOG4105CA3	membrane-bound lytic murein transglycosylase
O3Y_11125	ENOG4107QZM	n-acetylglutamate synthase
O3Y_11135	ENOG4107QYX	exodeoxyribonuclease v alpha
O3Y_11140	ENOG4107QKA	exodeoxyribonuclease V beta
O3Y_11145	ENOG4105DSY	exodeoxyribonuclease V, gamma
O3Y_11160	ENOG4105X2V	dna damage-inducible protein
O3Y_11165	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
O3Y_11175	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
O3Y_11180	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
O3Y_11195	ENOG4108Y51	tRNA-binding protein
O3Y_11200	ENOG41060NJ	transcriptional regulator
O3Y_11205	ENOG4105CNT	hydrolase family 2
O3Y_11215	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
O3Y_11220	ENOG4108IQE	Amp-dependent synthetase and ligase
O3Y_11225	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
O3Y_11230	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
O3Y_11240	ENOG4105EAC	phosphoserine phosphatase
O3Y_11250	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
O3Y_11255	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
O3Y_11260	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
O3Y_11265	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
O3Y_11270	ENOG4105D9N	nucleoside
O3Y_11275	ENOG4105EYA	deoxyribonuclease
O3Y_11285	ENOG4105BZG	amino acid carrier protein
O3Y_11300	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
O3Y_11305	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
O3Y_11310	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
O3Y_11315	ENOG4105D98	threonine synthase
O3Y_11320	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
O3Y_11335	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
O3Y_11345	ENOG41065U4	response regulator
O3Y_11350	ENOG4105BZU	Histidine kinase
O3Y_11360	ENOG4105N5T	Radical SAM Protein
O3Y_11375	ENOG4105CBC	glutamate synthase
O3Y_11380	ENOG4105BZ8	glutamate synthase
O3Y_11390	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
O3Y_11400	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
O3Y_11405	ENOG4105EN6	Membrane
O3Y_11410	ENOG4105VP0	transcriptional regulator, lysR family
O3Y_11415	ENOG4105EJ9	Membrane
O3Y_11420	ENOG4107RRE	RNA-directed DNA polymerase
O3Y_11445	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
O3Y_11450	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
O3Y_11460	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
O3Y_11465	ENOG4105M6F	mutator MutT protein
O3Y_11470	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
O3Y_11480	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
O3Y_11485	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
O3Y_11490	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
O3Y_11495	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
O3Y_11500	ENOG4105DFU	Cell wall formation (By similarity)
O3Y_11505	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
O3Y_11515	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
O3Y_11520	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
O3Y_11525	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
O3Y_11530	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
O3Y_11535	ENOG4105CJN	penicillin-binding protein
O3Y_11540	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
O3Y_11545	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
O3Y_11550	ENOG4107QN2	dihydrolipoyl dehydrogenase
O3Y_11555	ENOG4107QSN	dihydrolipoamide acetyltransferase
O3Y_11560	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
O3Y_11565	ENOG41073TP	transcriptional regulator
O3Y_11570	ENOG4105CGH	5'-nucleotidase
O3Y_11575	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
O3Y_11580	ENOG4105T95	Thiol disulfide interChange protein
O3Y_11585	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
O3Y_11590	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
O3Y_11600	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
O3Y_11610	ENOG4107QHF	type ii secretion system protein e
O3Y_11615	ENOG4105D7Q	type ii secretion system
O3Y_11620	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
O3Y_11625	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
O3Y_11630	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
O3Y_11640	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
O3Y_11645	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
O3Y_11650	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
O3Y_11655	ENOG4105IPS	esterase
O3Y_11660	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
O3Y_11665	ENOG4108SX3	cytoplasmic protein
O3Y_11670	ENOG41087AY	ADP-Ribose pyrophosphatase
O3Y_11675	ENOG4105DFG	type I secretion outer membrane protein
O3Y_11685	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
O3Y_11690	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_11695	ENOG4105I7R	Adenylate cyclase
O3Y_11700	ENOG4107IX6	phosphate transport regulator
O3Y_11705	ENOG4105CJ3	phosphate transporter
O3Y_11710	ENOG4106MWK	domain protein
O3Y_11725	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
O3Y_11730	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
O3Y_11735	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
O3Y_11745	ENOG4105DXN	mazG family
O3Y_11750	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
O3Y_11755	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
O3Y_11760	ENOG4105BZU	Histidine kinase
O3Y_11765	ENOG4108K0B	C-di-gmp phosphodiesterase
O3Y_11780	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
O3Y_11785	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
O3Y_11790	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
O3Y_11795	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
O3Y_11800	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
O3Y_11805	ENOG4105C3F	Signal peptidase i
O3Y_11810	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
O3Y_11815	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
O3Y_11820	ENOG4105VQK	sigma E regulatory protein, MucB RseB
O3Y_11830	ENOG4105EMN	RNA polymerase sigma factor
O3Y_11835	ENOG4108IYU	L-aspartate oxidase
O3Y_11845	ENOG4105Y75	tpr repeat protein
O3Y_11850	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
O3Y_11860	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
O3Y_11865	ENOG4105D0A	hydroxylase
O3Y_11875	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
O3Y_11880	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
O3Y_11885	ENOG4105E66	phosphoriboisomerase A
O3Y_11890	ENOG4108JQ1	Dehydrogenase
O3Y_11895	ENOG4108ZP8	Acetolactate synthase small subunit
O3Y_11900	ENOG4105C7K	acetolactate synthase
O3Y_11905	ENOG4108IQE	Amp-dependent synthetase and ligase
O3Y_11910	ENOG41064T2	transcriptional regulator, lysR family
O3Y_11930	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
O3Y_11935	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
O3Y_11940	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
O3Y_11945	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
O3Y_11955	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
O3Y_11965	ENOG4108K5H	permease YjgP YjgQ family protein
O3Y_11970	ENOG4108M8S	permease YjgP YjgQ family protein
O3Y_11975	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
O3Y_11980	ENOG4105MYG	DNA polymerase iii, chi subunit
O3Y_11985	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
O3Y_11990	ENOG4105C5I	Dehydrogenase
O3Y_11995	ENOG4105D3G	Pseudouridine synthase
O3Y_12000	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
O3Y_12010	ENOG4108IAB	Phoh family
O3Y_12015	ENOG4105DBV	ornithine carbamoyltransferase
O3Y_12025	ENOG4105CXT	aspartate transcarbamylase
O3Y_12030	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
O3Y_12035	ENOG4105KME	endoribonuclease L-psp
O3Y_12040	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
O3Y_12045	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
O3Y_12050	ENOG4105VFK	BolA family
O3Y_12060	ENOG4105E3I	toluene tolerance
O3Y_12065	ENOG4107PE3	Mammalian cell entry related domain protein
O3Y_12070	ENOG4105CY3	ABC transporter, permease
O3Y_12075	ENOG4105DHJ	ABC, transporter
O3Y_12085	ENOG4105C2X	Arabinose 5-phosphate isomerase
O3Y_12090	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
O3Y_12100	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
O3Y_12105	ENOG4108IUZ	ABC transporter
O3Y_12110	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
O3Y_12115	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
O3Y_12120	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
O3Y_12125	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
O3Y_12130	ENOG41080Z8	PHOSPHOCARRIER protein
O3Y_12135	ENOG4105CJW	magnesium transporter
O3Y_12140	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
O3Y_12145	ENOG4105N42	UPF0307 protein
O3Y_12150	ENOG4107T0D	ABC, transporter
O3Y_12155	ENOG4106SMU	thiamine transporter membrane protein
O3Y_12160	ENOG4105DP9	ABC transporter
O3Y_12165	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
O3Y_12170	ENOG4105DFU	Cell wall formation (By similarity)
O3Y_12175	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
O3Y_12180	ENOG4105F0N	pyrophosphate phospho-hydrolase
O3Y_12185	ENOG41066HZ	AIG2-like family
O3Y_12195	ENOG4105CFU	surface antigen
O3Y_12200	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
O3Y_12205	ENOG4108UUE	Transcriptional regulator
O3Y_12220	ENOG4105C19	ABC transporter
O3Y_12240	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
O3Y_12245	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
O3Y_12250	ENOG4105C11	sulfate adenylyltransferase), subunit 2
O3Y_12255	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
O3Y_12260	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
O3Y_12270	ENOG4105C1J	atp-dependent rna helicase
O3Y_12275	ENOG4107YB6	acetyltransferase, (GNAT) family
O3Y_12280	ENOG4108SXK	Transporter Drug Metabolite Exporter family
O3Y_12285	ENOG4108UBT	opacity-associated protein
O3Y_12290	ENOG4108V1T	peptidylprolyl cis-trans isomerase
O3Y_12300	ENOG4108ZT0	50S ribosomal protein l17
O3Y_12305	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
O3Y_12310	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
O3Y_12315	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
O3Y_12320	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
O3Y_12330	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
O3Y_12335	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
O3Y_12340	ENOG4105VPB	50S ribosomal protein L30
O3Y_12345	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
O3Y_12350	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
O3Y_12355	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
O3Y_12360	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
O3Y_12365	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
O3Y_12370	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
O3Y_12375	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
O3Y_12380	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
O3Y_12385	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
O3Y_12390	ENOG41083MP	50s ribosomal protein l29
O3Y_12395	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
O3Y_12400	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
O3Y_12405	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
O3Y_12410	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
O3Y_12415	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
O3Y_12420	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
O3Y_12425	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
O3Y_12430	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
O3Y_12435	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
O3Y_12440	ENOG4105C2N	RNA methyltransferase TrmH family group 3
O3Y_12445	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
O3Y_12450	ENOG4105E68	Sulfatase
O3Y_12455	ENOG4108UV7	flagellar protein motX
O3Y_12460	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
O3Y_12465	ENOG4105D44	asparaginase
O3Y_12470	ENOG4108YZY	peptidylprolyl cis-trans isomerase
O3Y_12485	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
O3Y_12490	ENOG4105C5H	ABC transporter
O3Y_12500	ENOG4105DNZ	Alpha Beta Hydrolase
O3Y_12510	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
O3Y_12515	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
O3Y_12525	ENOG4105C26	Dehydrogenase
O3Y_12535	ENOG4105C8Y	Acetylornithine aminotransferase
O3Y_12540	ENOG4105DDQ	anthranilate synthase
O3Y_12545	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
O3Y_12560	ENOG4105C31	Tryptophanyl-tRNA synthetase
O3Y_12565	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
O3Y_12570	ENOG4105DJV	ribulose-phosphate 3-epimerase
O3Y_12575	ENOG4105DFE	Dna adenine methylase
O3Y_12585	ENOG4105D49	3-dehydroquinate synthase
O3Y_12590	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
O3Y_12595	ENOG4105E4G	Type IV pilus
O3Y_12620	ENOG4108JQC	penicillin-binding protein 1A
O3Y_12630	ENOG4105EHV	domain protein
O3Y_12635	ENOG4107QN2	dihydrolipoyl dehydrogenase
O3Y_12645	ENOG4105CH7	arginosuccinase
O3Y_12650	ENOG4105CDH	Citrulline--aspartate ligase
O3Y_12655	ENOG4105CAS	nag kinase
O3Y_12660	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
O3Y_12665	ENOG4105CWC	Acetylornithine deacetylase
O3Y_12670	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
O3Y_12680	ENOG4105D7W	serine acetyltransferase
O3Y_12685	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
O3Y_12690	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
O3Y_12695	ENOG4107YZP	Rhodanese domain protein
O3Y_12700	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
O3Y_12710	ENOG4105E33	succinate dehydrogenase
O3Y_12715	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
O3Y_12720	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
O3Y_12725	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
O3Y_12730	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
O3Y_12740	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
O3Y_12745	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
O3Y_12770	ENOG4105CP7	Triose-phosphate isomerase
O3Y_12780	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
O3Y_12785	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
O3Y_12790	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
O3Y_12795	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
O3Y_12800	ENOG41063M6	Cell Division Protein
O3Y_12805	ENOG4105ETE	Transcriptional regulator (LacI family
O3Y_12810	ENOG4105C25	Primosomal protein n'
O3Y_12815	ENOG4105VFB	Binds the 23S rRNA (By similarity)
O3Y_12820	ENOG4105C6K	Malic enzyme
O3Y_12825	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
O3Y_12830	ENOG4105C28	cystathionine
O3Y_12835	ENOG4105CFH	Aspartokinase
O3Y_12845	ENOG4105SYT	Methylenetetrahydrofolate reductase
O3Y_12850	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
O3Y_12855	ENOG4105CBT	Fructose-1,6-bisphosphatase
O3Y_12860	ENOG4105CTQ	phosphohexokinase
O3Y_12865	ENOG41076HS	cation diffusion facilitator family transporter
O3Y_12875	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
O3Y_12880	ENOG4105E0F	Histidine kinase
O3Y_12890	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
O3Y_12895	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
O3Y_12900	ENOG4105BZU	Histidine kinase
O3Y_12905	ENOG4108IJ0	Aspartate ammonia-lyase
O3Y_12910	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
O3Y_12925	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
O3Y_12935	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
O3Y_12945	ENOG4107QN1	sodium solute
O3Y_12950	ENOG4105EX9	Membrane
O3Y_12955	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
O3Y_12960	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
O3Y_12965	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
O3Y_12970	ENOG4105CB5	ATP-dependent DNA helicase recG
O3Y_12975	ENOG4105C2W	permease
O3Y_12980	ENOG4105E0F	Histidine kinase
O3Y_12985	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
O3Y_12990	ENOG4108RRZ	Transcription elongation factor GreB
O3Y_12995	ENOG4105BZM	domain protein
O3Y_13005	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
O3Y_13010	ENOG4105MJ2	Competence protein
O3Y_13015	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
O3Y_13020	ENOG4107RK2	ADP-ribose diphosphatase NudE
O3Y_13025	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
O3Y_13030	ENOG4105PIC	general secretion pathway protein N
O3Y_13035	ENOG4105U1E	general secretion pathway protein M
O3Y_13040	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
O3Y_13045	ENOG4108RTD	type II secretion system protein K
O3Y_13050	ENOG4108WWZ	General secretion pathway protein J
O3Y_13055	ENOG4105X5Z	General secretion pathway protein I
O3Y_13060	ENOG4105VWV	general secretion pathway protein h
O3Y_13065	ENOG4108VAU	general secretion pathway protein G
O3Y_13070	ENOG4105D7Q	type ii secretion system
O3Y_13075	ENOG4107QHF	type ii secretion system protein e
O3Y_13085	ENOG4108XKW	General secretion pathway protein C
O3Y_13090	ENOG4105VEJ	Heat shock protein
O3Y_13095	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
O3Y_13100	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
O3Y_13110	ENOG4105SUU	thioesterase domain
O3Y_13115	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
O3Y_13135	ENOG4105C5F	glutamine synthetase
O3Y_13145	ENOG4105CUX	Signal transduction histidine kinase
O3Y_13150	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
O3Y_13155	ENOG4105BZU	Histidine kinase
O3Y_13160	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
O3Y_13170	ENOG4108RR8	protoporphyrinogen oxidase
O3Y_13175	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
O3Y_13180	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
O3Y_13185	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
O3Y_13190	ENOG4105CHU	acetyl-coa acetyltransferase
O3Y_13195	ENOG4105F52	Transcriptional regulator
O3Y_13200	ENOG4105CZQ	inner membrane transport protein YdhC
O3Y_13205	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
O3Y_13210	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
O3Y_13215	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
O3Y_13220	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
O3Y_13225	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
O3Y_13230	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
O3Y_13235	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
O3Y_13240	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
O3Y_13245	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
O3Y_13250	ENOG410684E	atp synthase
O3Y_13255	ENOG4105FA0	parb-like partition protein
O3Y_13260	ENOG4107QJE	Chromosome Partitioning Protein
O3Y_13265	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
O3Y_13270	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
O3Y_13533	ENOG4105CDY	transcriptional regulatory protein
O3Y_13538	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
O3Y_13543	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_13548	ENOG4108YYI	Protein of unknown function (DUF2810)
O3Y_13553	ENOG41061ZR	Transcriptional regulator
O3Y_13558	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
O3Y_13563	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
O3Y_13568	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
O3Y_13573	ENOG4108WC9	type VI secretion system effector, hcp1 family
O3Y_13578	ENOG4105CS6	Rhs element vgr protein
O3Y_13603	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
O3Y_13613	ENOG4105C8P	)-transporter
O3Y_13618	ENOG4108Q67	UPF0319 protein
O3Y_13643	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_13663	ENOG4105EYK	Phosphatidylglycerophosphatase B
O3Y_13668	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
O3Y_13693	ENOG4105D6U	Sodium Glutamate Symporter
O3Y_13698	ENOG4105YE1	PilZ domain
O3Y_13713	ENOG4105EFX	secretion protein, HlyD family
O3Y_13718	ENOG4105KK7	inner membrane protein YiaW
O3Y_13723	ENOG4106TD9	Diguanylate cyclase
O3Y_13738	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
O3Y_13743	ENOG4107SEY	Conserved Protein
O3Y_13753	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
O3Y_13758	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
O3Y_13768	ENOG4105C1J	atp-dependent rna helicase
O3Y_13773	ENOG4105CUG	Oligopeptidase b
O3Y_13803	ENOG4105CVA	phosphate
O3Y_13808	ENOG4105C8U	phosphate abc transporter
O3Y_13813	ENOG4105E2Z	phosphate ABC transporter (Permease
O3Y_13818	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
O3Y_13823	ENOG4105BZU	Histidine kinase
O3Y_13833	ENOG4105DWD	nucleoside recognition domain protein
O3Y_13838	ENOG4105CHH	sulfate transporter
O3Y_13848	ENOG4105DR5	peptidase
O3Y_13853	ENOG4105BZU	Histidine kinase
O3Y_13858	ENOG4105EQ2	LysR family Transcriptional regulator
O3Y_13863	ENOG4105E5M	Multidrug resistance protein D
O3Y_13868	ENOG4108Z4X	TRANSCRIPTIONal
O3Y_13888	ENOG4105CK2	sodium dicarboxylate symporter
O3Y_13928	ENOG4107RH7	Nicotinate phosphoribosyltransferase
O3Y_13933	ENOG4105D9R	oxidoreductase
O3Y_13943	ENOG4105BZU	Histidine kinase
O3Y_13948	ENOG4107VXZ	Hydrolase
O3Y_13958	ENOG4105D3G	Pseudouridine synthase
O3Y_14018	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
O3Y_14023	ENOG4108JUB	Transcriptional regulator
O3Y_14053	ENOG4105CS6	Rhs element vgr protein
O3Y_14068	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
O3Y_14073	ENOG4105C2J	ABC transporter
O3Y_14078	ENOG4105CNN	ABC, transporter
O3Y_14083	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
O3Y_14088	ENOG4108RVA	ribokinase
O3Y_14093	ENOG4105ETE	Transcriptional regulator (LacI family
O3Y_14098	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
O3Y_14103	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
O3Y_14108	ENOG4108I5U	Uridine phosphorylase
O3Y_14118	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
O3Y_14123	ENOG4105CXY	transporter
O3Y_14138	ENOG4105CQZ	Histidine kinase
O3Y_14143	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
O3Y_14163	ENOG4105D5U	fad dependent oxidoreductase
O3Y_14173	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
O3Y_14183	ENOG4105KJM	monovalent cation h antiporter subunit g
O3Y_14188	ENOG41080TA	Multiple resistance and ph regulation protein f
O3Y_14193	ENOG4105SC1	monovalent cation H antiporter subunit E
O3Y_14198	ENOG4108JPZ	Monovalent cation H antiporter subunit D
O3Y_14203	ENOG4105MKQ	Monovalent cation H antiporter subunit C
O3Y_14208	ENOG4105D65	subunit l
O3Y_14218	ENOG4105Q9Y	Universal stress protein
O3Y_14223	ENOG4105CIC	tryptophan-specific transport protein
O3Y_14228	ENOG4105C0F	tryptophanase EC 4.1.99.1
O3Y_14233	ENOG4105VRT	cytoplasmic protein
O3Y_14243	ENOG4105BZU	Histidine kinase
O3Y_14248	ENOG4105VEQ	Cold shock protein
O3Y_14283	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
O3Y_14288	ENOG41069D7	Methyl-accepting chemotaxis
O3Y_14308	ENOG4105D9N	nucleoside
O3Y_14313	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
O3Y_14323	ENOG4108JUA	Transcriptional regulator
O3Y_14328	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
O3Y_14333	ENOG4105VEQ	Cold shock protein
O3Y_14358	ENOG4108UNF	response regulator
O3Y_14368	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
O3Y_14373	ENOG4105C5I	Dehydrogenase
O3Y_14393	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
O3Y_14423	ENOG4108RS6	transposase
O3Y_14428	ENOG4105C1J	atp-dependent rna helicase
O3Y_14433	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
O3Y_14438	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
O3Y_14443	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
O3Y_14448	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
O3Y_14453	ENOG4105BZU	Histidine kinase
O3Y_14463	ENOG4107S6Z	Na H antiporter
O3Y_14468	ENOG4105E5M	Multidrug resistance protein D
O3Y_14478	ENOG4105BZU	Histidine kinase
O3Y_14483	ENOG4105KUU	lipolytic protein G-D-S-L family
O3Y_14488	ENOG4106M3D	hemolysin
O3Y_14493	ENOG4108N3W	hemolysin secretion protein
O3Y_14498	ENOG4107IFA	Lipase (EC 3.1.1.3)
O3Y_14508	ENOG4107G87	m6 family metalloprotease domain protein
O3Y_14528	ENOG4105DHS	permease protein
O3Y_14533	ENOG4105CM4	permease protein
O3Y_14538	ENOG4108IPW	abc transporter atp-binding protein
O3Y_14558	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
O3Y_14578	ENOG4105ETX	regulatoR
O3Y_14593	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
O3Y_14603	ENOG410667J	hydrolase
O3Y_14633	ENOG4105DS1	cytochrome b561
O3Y_14663	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
O3Y_14668	ENOG4105BZU	Histidine kinase
O3Y_14693	ENOG4107QVI	Methyltransferase, type 11
O3Y_14708	ENOG4105C2C	drug resistance transporter, Bcr CflA
O3Y_14713	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_14723	ENOG4105DZ1	carboxypeptidase
O3Y_14743	ENOG4108RS6	transposase
O3Y_14748	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
O3Y_14753	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
O3Y_14758	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
O3Y_14768	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
O3Y_14778	ENOG4105F2I	Transposase
O3Y_14803	ENOG4105C22	threonyL-tRNA synthetase
O3Y_14808	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
O3Y_14813	ENOG41082NX	50s ribosomal protein l35
O3Y_14818	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
O3Y_14873	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
O3Y_14913	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
O3Y_14953	ENOG4105D9U	N-acetyltransferase
O3Y_14958	ENOG4105QNF	Outer membrane lipoprotein
O3Y_14988	ENOG4105VXN	addiction module toxin, RelE StbE family
O3Y_14998	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
O3Y_15053	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
O3Y_15073	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
O3Y_15098	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
O3Y_15113	ENOG4105QNF	Outer membrane lipoprotein
O3Y_15133	ENOG4105YGK	Pfam:UPF0157
O3Y_15143	ENOG4105N14	lysine exporter protein LysE YggA
O3Y_15343	ENOG41080ET	plasmid maintenance system killer protein
O3Y_15348	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
O3Y_15363	ENOG4108S58	Phenazine biosynthesis protein PhzF
O3Y_15393	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
O3Y_15418	ENOG4105QNF	Outer membrane lipoprotein
O3Y_15473	ENOG4105D9U	N-acetyltransferase
O3Y_15573	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
O3Y_15593	ENOG4105QNF	Outer membrane lipoprotein
O3Y_15648	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
O3Y_15703	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
O3Y_15733	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
O3Y_15738	ENOG4105W08	virulence gene repressor rsal
O3Y_15753	ENOG4105F2I	Transposase
O3Y_15758	ENOG4105EQK	-acetyltransferase
O3Y_15773	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
O3Y_15858	ENOG4108RS6	transposase
O3Y_15918	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
O3Y_15938	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
O3Y_15943	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
O3Y_15948	ENOG4105CGF	Aromatic amino acid aminotransferase
O3Y_15953	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
O3Y_15958	ENOG4105DM4	PTS System
O3Y_15963	ENOG4105DE4	1-phosphofructokinase
O3Y_15968	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
O3Y_15973	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
O3Y_15978	ENOG4107RFY	SbcCD D subunit
O3Y_15983	ENOG4105EYH	Exonuclease
O3Y_15988	ENOG4108MGY	Histidine kinase
O3Y_15993	ENOG4107KBT	8-Amino-7-oxononanoate synthase
O3Y_16003	ENOG4105CMQ	Chloride channel
O3Y_16008	ENOG4105CKI	cobalamin synthesis protein
O3Y_16013	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
O3Y_16018	ENOG4105DFH	Transport of potassium into the cell (By similarity)
O3Y_16023	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
O3Y_16028	ENOG4105C08	Histidine kinase
O3Y_16033	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
O3Y_16038	ENOG410607N	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity)
O3Y_16043	ENOG4108RHM	integral membrane protein
O3Y_16058	ENOG4105EPM	Diguanylate phosphodiesterase
O3Y_16068	ENOG4105DS1	cytochrome b561
O3Y_16078	ENOG4105TMB	Formate nitrite transporter
O3Y_16088	ENOG4105DUM	transcriptional regulator, lysR family
O3Y_16093	ENOG4108UQ5	membrane protein YcdZ
O3Y_16098	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
O3Y_16103	ENOG4105CGH	5'-nucleotidase
O3Y_16108	ENOG4105DU1	integral membrane protein, terc
O3Y_16118	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
O3Y_16148	ENOG4105BZU	Histidine kinase
O3Y_16153	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
O3Y_16163	ENOG4105BZU	Histidine kinase
O3Y_16178	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
O3Y_16183	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
O3Y_16193	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
O3Y_16213	ENOG4108ZJT	translation initiation factor, Sui1
O3Y_16223	ENOG4105CPF	Cell wall formation (By similarity)
O3Y_16233	ENOG4105CD5	CoA-binding domain protein
O3Y_16238	ENOG4105CWB	LysR family transcriptional Regulator
O3Y_16258	ENOG4105KA0	thioesterase Superfamily protein
O3Y_16278	ENOG4105CYM	Glutathione S-transferase
O3Y_16293	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
O3Y_16298	ENOG4108JQ5	ABC transporter
O3Y_16303	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
O3Y_16308	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
O3Y_16313	ENOG4105E43	Extracellular solute-binding protein, family 5
O3Y_16338	ENOG4105DUX	Transporter
O3Y_16353	ENOG4107RCV	ABC transporter, permease
O3Y_16368	ENOG4107STF	Involved in phosphonate degradation (By similarity)
O3Y_16373	ENOG4108JPW	Aminotransferase
O3Y_16378	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
O3Y_16383	ENOG4105NXH	GreA GreB family elongation factor
O3Y_16388	ENOG4105PAD	Hydrolase
O3Y_16398	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
O3Y_16403	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
O3Y_16408	ENOG4105CKU	formyltetrahydrofolate synthetase
O3Y_16413	ENOG4105E0X	reductase
O3Y_16418	ENOG4105EUJ	GTP cyclohydrolase i
O3Y_16423	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
O3Y_16428	ENOG4105D06	uba thif-type nad fad binding protein
O3Y_16438	ENOG4105KHC	sulfurtransferase
O3Y_16443	ENOG4107RHR	regulatoR
O3Y_16453	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
O3Y_16458	ENOG4105CV1	Transketolase (EC 2.2.1.1)
O3Y_16483	ENOG4108M3J	Dehydrogenase
O3Y_16498	ENOG4105RA2	Membrane
O3Y_16508	ENOG4105ETT	transcriptional Regulator, LysR family
O3Y_16513	ENOG41067V3	Antibiotic biosynthesis monooxygenase
O3Y_16518	ENOG4108RCM	Nitroreductase
O3Y_16543	ENOG41080HT	Transcriptional regulator, arsr family
O3Y_16553	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
O3Y_16608	ENOG4105ETE	Transcriptional regulator (LacI family
O3Y_16613	ENOG4107R3K	hydrolase
O3Y_16618	ENOG4105D7K	pfkb domain protein
O3Y_16623	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
O3Y_16628	ENOG4108NVR	Methyl-accepting chemotaxis
O3Y_16633	ENOG4108ZG0	Ompa motb domain protein
O3Y_16638	ENOG4108V1T	peptidylprolyl cis-trans isomerase
O3Y_16643	ENOG4107VXZ	Hydrolase
O3Y_16648	ENOG4108N3W	hemolysin secretion protein
O3Y_16653	ENOG4105CEE	C4-dicarboxylate transporter
O3Y_16658	ENOG4105EJQ	L-serine dehydratase
O3Y_16678	ENOG4105ETE	Transcriptional regulator (LacI family
O3Y_16683	ENOG4105WH1	Two component transcriptional regulator luxr family
O3Y_16688	ENOG4105BZU	Histidine kinase
O3Y_16703	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
O3Y_16723	ENOG4105DHT	Metal Dependent Phosphohydrolase
O3Y_16728	ENOG4108KX4	response regulator
O3Y_16733	ENOG4105BZU	Histidine kinase
O3Y_16738	ENOG4105CXY	transporter
O3Y_16743	ENOG4105C4Y	ABC transporter
O3Y_16748	ENOG4107RCV	ABC transporter, permease
O3Y_16753	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
O3Y_16758	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
O3Y_16768	ENOG4105CHU	acetyl-coa acetyltransferase
O3Y_16778	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
O3Y_16783	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
O3Y_16798	ENOG4105BZU	Histidine kinase
O3Y_16803	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
O3Y_16813	ENOG4108I6A	alcohol dehydrogenase
O3Y_16823	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
O3Y_16833	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
O3Y_16838	ENOG4105CXY	transporter
O3Y_16843	ENOG4105CA9	Pyruvate kinase
O3Y_16848	ENOG4105BZU	Histidine kinase
O3Y_16853	ENOG4108SV3	Tmao reductase system periplasmic protein tort
O3Y_16858	ENOG4108Z5K	methylglyoxal synthase
O3Y_16863	ENOG4108RWI	nicotinamidase
O3Y_16868	ENOG41080IJ	Diacylglycerol kinase
O3Y_16883	ENOG41088T4	Helicase IV
O3Y_16888	ENOG4105EM2	membrane
O3Y_16918	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
O3Y_16923	ENOG4105E0C	molybdate abc transporter
O3Y_16928	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
O3Y_16933	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
O3Y_16973	ENOG4105BZU	Histidine kinase
O3Y_16978	ENOG4108QGH	periplasmic
O3Y_16988	ENOG41082IR	Excinuclease ABC C subunit domain protein
O3Y_17018	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
O3Y_17023	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
O3Y_17028	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
O3Y_17033	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
O3Y_17038	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
O3Y_17043	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
O3Y_17048	ENOG4105K63	Thioredoxin
O3Y_17068	ENOG4105DUM	transcriptional regulator, lysR family
O3Y_17073	ENOG4105DMR	ABC, transporter
O3Y_17078	ENOG4105GBT	ABC transporter
O3Y_17083	ENOG4106PMH	Extracellular solute-binding protein family 3
O3Y_17088	ENOG4105E5Z	arginine transporter ATP-binding subunit
O3Y_17093	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
O3Y_17103	ENOG4108YZ4	nudix hydrolase
O3Y_17108	ENOG4105C5W	Aldolase
O3Y_17113	ENOG4106RE7	Cytochrome
O3Y_17118	ENOG4108IG5	Transcriptional regulator
O3Y_17123	ENOG4105C1J	atp-dependent rna helicase
O3Y_17128	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
O3Y_17138	ENOG4105E0U	tyrosine-specific transport protein
O3Y_17143	ENOG4108N3W	hemolysin secretion protein
O3Y_17148	ENOG4105CMR	udp-glucose 4-epimerase
O3Y_17153	ENOG4105E7W	lamb ycsf family protein
O3Y_17163	ENOG4107R7A	Allophanate hydrolase subunit 2
O3Y_17173	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
O3Y_17178	ENOG4105CV6	ABC transporter, permease
O3Y_17183	ENOG4108I0Y	(ABC) transporter
O3Y_17193	ENOG4105RKW	reductase (By
O3Y_17213	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
O3Y_17258	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
O3Y_17273	ENOG4107RE1	Inosine-guanosine kinase
O3Y_17278	ENOG4105E0M	Sulfatase
O3Y_17288	ENOG4105C1J	atp-dependent rna helicase
O3Y_17293	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
O3Y_17303	ENOG4105CVA	phosphate
O3Y_17313	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
O3Y_17318	ENOG4108M1A	Chitin-binding protein
O3Y_17323	ENOG4105D4Y	metalloprotease
O3Y_17333	ENOG4105CYW	agmatinase
O3Y_17338	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
O3Y_17348	ENOG4105CJW	magnesium transporter
O3Y_17353	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
O3Y_17358	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
O3Y_17368	ENOG4105CZK	Aspartate kinase
O3Y_17373	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
O3Y_17378	ENOG4108JPW	Aminotransferase
O3Y_17383	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
O3Y_17388	ENOG41090A4	Pterin carbinolamine dehydratase
O3Y_17393	ENOG4105MIR	Phenylalanine 4-monooxygenase
O3Y_17398	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
O3Y_17408	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
O3Y_17413	ENOG4105EGI	Transcriptional regulator
O3Y_17428	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
O3Y_17433	ENOG4105C37	(CBS) domain
O3Y_17438	ENOG4108UKZ	OsmC family
O3Y_17443	ENOG4107YWA	deoxycytidylate deaminase
O3Y_17463	ENOG4105DVH	amino acid
O3Y_17468	ENOG4106TD9	Diguanylate cyclase
O3Y_17478	ENOG4108VAC	response regulator
O3Y_17483	ENOG4108HRK	Histidine kinase
O3Y_17498	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
O3Y_17503	ENOG4105C19	ABC transporter
O3Y_17518	ENOG4107RGM	aldo keto reductase
O3Y_17523	ENOG4107T9C	Alpha amylase catalytic region
O3Y_17538	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
O3Y_17543	ENOG4108M0H	Extracellular lipase
O3Y_17548	ENOG4107SDU	Methyl-accepting chemotaxis
O3Y_17553	ENOG4105D4Y	metalloprotease
O3Y_17558	ENOG4105EIF	outer membrane protein W
O3Y_17563	ENOG41061WM	D-Alanyl-D-Alanine
O3Y_17568	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
O3Y_17573	ENOG4105C4M	(Ubiquinol oxidase) subunit I
O3Y_17578	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
O3Y_17593	ENOG4105BZC	d-serine deaminase
O3Y_17598	ENOG4105W8I	Transcriptional regulator
O3Y_17638	ENOG4105CPQ	Dehydrogenase
O3Y_17643	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
O3Y_17663	ENOG4105EXG	Transcriptional regulator
O3Y_17668	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
O3Y_17688	ENOG4107SSZ	Phosphatase
O3Y_17693	ENOG4105DHT	Metal Dependent Phosphohydrolase
O3Y_17698	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
O3Y_17703	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
O3Y_17708	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
O3Y_17733	ENOG4105BZW	Glycerate kinase
O3Y_17738	ENOG4105C6Z	Gluconate
O3Y_17743	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
O3Y_17748	ENOG4108NVR	Methyl-accepting chemotaxis
O3Y_17753	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
O3Y_17758	ENOG41090JE	Utilization Protein
O3Y_17763	ENOG4105D4P	Coproporphyrinogen iii oxidase
O3Y_17768	ENOG4105WQ5	TonB family
O3Y_17773	ENOG41090AP	transport protein
O3Y_17778	ENOG4106GFD	transport protein
O3Y_17783	ENOG4107R4I	Periplasmic binding protein
O3Y_17788	ENOG4105EHG	Permease protein
O3Y_17793	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
O3Y_17823	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_17828	ENOG4105QVC	MOSC domain-containing protein
O3Y_17828	ENOG4105QVC	MOSC domain-containing protein
O3Y_17833	ENOG4105EKE	dihydroorotase
O3Y_17843	ENOG4105KAF	membrAne
O3Y_17853	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
O3Y_17858	ENOG4105CKW	Inner membrane protein yedI
O3Y_17863	ENOG4108ESY	Metal dependent phosphohydrolase
O3Y_17868	ENOG4105VEQ	Cold shock protein
O3Y_17893	ENOG4105BZU	Histidine kinase
O3Y_17898	ENOG4105E98	transcriptional regulator DeoR family
O3Y_17913	ENOG4105EG2	ABC transporter, permease
O3Y_17918	ENOG4105D56	permease protein
O3Y_17923	ENOG4107FKK	extracellular solute-binding protein family 1
O3Y_17928	ENOG4108IJ9	(ABC) transporter
O3Y_17933	ENOG4108HK0	-acetyltransferase
O3Y_17948	ENOG4105K8R	UPF0145 protein
O3Y_17953	ENOG41086KC	Transcriptional regulator
O3Y_17958	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
O3Y_17963	ENOG4107R88	Chemotaxis protein (CheV)
O3Y_17968	ENOG4105K56	Transcriptional regulator
O3Y_17973	ENOG4106TD9	Diguanylate cyclase
O3Y_17988	ENOG4105BZU	Histidine kinase
O3Y_18008	ENOG4105ETT	transcriptional Regulator, LysR family
O3Y_18013	ENOG4108K0B	C-di-gmp phosphodiesterase
O3Y_18023	ENOG4105EUB	pirin domain protein
O3Y_18028	ENOG4105NBK	UPF0345 protein
O3Y_18038	ENOG4105E5W	Transporter
O3Y_18048	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_18053	ENOG4105DAN	ATP-dependent protease
O3Y_18063	ENOG4108JQ5	ABC transporter
O3Y_18068	ENOG4105E89	ABC transporter
O3Y_18073	ENOG4107SDU	Methyl-accepting chemotaxis
O3Y_18088	ENOG4105CC0	LysR family Transcriptional regulator
O3Y_18093	ENOG4105DAA	L-lactate
O3Y_18098	ENOG4105DMF	Dehydrogenase
O3Y_18108	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
O3Y_18118	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
O3Y_18128	ENOG4105C1J	atp-dependent rna helicase
O3Y_18133	ENOG4105CR8	Transcriptional regulator
O3Y_18143	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
O3Y_18158	ENOG4105BZ1	(ABC) transporter
O3Y_18168	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
O3Y_18203	ENOG4105K56	Transcriptional regulator
O3Y_18208	ENOG4108ZHJ	Organic hydroperoxide resistance protein
O3Y_18218	ENOG4108SXK	Transporter Drug Metabolite Exporter family
O3Y_18223	ENOG4105VW4	glutaredoxin 3
O3Y_18228	ENOG4108P2H	Inner membrane protein YjiG
O3Y_18233	ENOG41074DU	domain protein
O3Y_18238	ENOG4105DN9	Na H antiporter
O3Y_18248	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
O3Y_18253	ENOG4105D03	DNA-3-methyladenine glycosylase II
O3Y_18258	ENOG4108VGI	doxx family
O3Y_18283	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
O3Y_18293	ENOG4107W52	maltose operon periplasmic protein
O3Y_18298	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
O3Y_18313	ENOG4108N3W	hemolysin secretion protein
O3Y_18328	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_18338	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
O3Y_18343	ENOG4105CDA	abc transporter atp-binding protein
O3Y_18353	ENOG4106TNF	Periplasmic binding protein
O3Y_18358	ENOG4105EZ7	amino acid ABC transporter
O3Y_18363	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
O3Y_18373	ENOG4105DR5	peptidase
O3Y_18378	ENOG4105CTS	PTS system mannitol-specific
O3Y_18383	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
O3Y_18388	ENOG4105E61	Mannitol repressor protein
O3Y_18393	ENOG4105EP9	oxidoreductase
O3Y_18423	ENOG4108RYK	Nad-dependent epimerase dehydratase
O3Y_18428	ENOG4105JQN	Transcriptional regulator
O3Y_18433	ENOG41069D7	Methyl-accepting chemotaxis
O3Y_18438	ENOG4105EMU	Dehydrogenase
O3Y_18443	ENOG4105JQN	Transcriptional regulator
O3Y_18453	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
O3Y_18458	ENOG4105D5Q	Arginine ornithine antiporter
O3Y_18463	ENOG4105CXN	decarboxylase
O3Y_18473	ENOG4107RGH	Aldehyde dehydrogenase
O3Y_18478	ENOG4105EW9	transcriptional regulator AsnC family
O3Y_18483	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_18493	ENOG4105CK7	Sodium proline symporter
O3Y_18503	ENOG4105C26	Dehydrogenase
O3Y_18518	ENOG4105E6M	Sulphatase-modifying factor protein
O3Y_18528	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
O3Y_18533	ENOG4107QZV	Type I secretion membrane fusion protein
O3Y_18548	ENOG4108JJA	ABC, transporter
O3Y_18558	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
O3Y_18568	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_18573	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
O3Y_18578	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
O3Y_18583	ENOG4105BZU	Histidine kinase
O3Y_18588	ENOG4105C8Q	Methyl-accepting chemotaxis
O3Y_18593	ENOG4108V3W	Chemotaxis protein, CheW
O3Y_18598	ENOG4108V3W	Chemotaxis protein, CheW
O3Y_18603	ENOG4105CBS	Chea signal transduction histidine kinase
O3Y_18608	ENOG4108VYJ	response regulator receiver protein
O3Y_18623	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
O3Y_18628	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
O3Y_18633	ENOG4108JQ6	ABC transporter
O3Y_18638	ENOG4105DIJ	Phosphoethanolamine transferase
O3Y_18643	ENOG4105DHQ	Histidine kinase
O3Y_18648	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
O3Y_18678	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
O3Y_18683	ENOG4107RUE	extracellular solute-binding protein family 1
O3Y_18688	ENOG4106RMF	ParB family