locus-tag	class	description
VCLMA_A0001	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCLMA_A0002	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
VCLMA_A0003	COG0706	membrane insertase activity
VCLMA_A0004	COG0594	ribonuclease P activity
VCLMA_A0005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VCLMA_A0006	COG1126	abc transporter atp-binding protein
VCLMA_A0010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VCLMA_A0011	COG0592	DNA-directed DNA polymerase activity
VCLMA_A0012	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VCLMA_A0016	COG0071	Belongs to the small heat shock protein (HSP20) family
VCLMA_A0017	COG3977	Valine--pyruvate aminotransferase
VCLMA_A0018	COG0751	glycine-tRNA ligase activity
VCLMA_A0019	COG0752	glycyl-tRNA synthetase alpha subunit
VCLMA_A0020	COG2119	membrane
VCLMA_A0022	COG0425	Belongs to the sulfur carrier protein TusA family
VCLMA_A0024	COG0604	alcohol dehydrogenase
VCLMA_A0026	COG0129	dihydroxy-acid dehydratase activity
VCLMA_A0027	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCLMA_A0031	COG0204	Acyl-transferase
VCLMA_A0032	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCLMA_A0033	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VCLMA_A0035	COG3084	Protein conserved in bacteria
VCLMA_A0037	COG4326	sporulation control protein
VCLMA_A0038	COG1272	protein, Hemolysin III
VCLMA_A0040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCLMA_A0041	COG0569	domain protein
VCLMA_A0042	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VCLMA_A0042	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCLMA_A0043	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VCLMA_A0044	COG0242	peptide deformylase activity
VCLMA_A0045	COG1652	LysM domain
VCLMA_A0046	COG0758	DNA mediated transformation
VCLMA_A0047	COG2922	Belongs to the Smg family
VCLMA_A0048	COG0551	DNA topoisomerase type I activity
VCLMA_A0049	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VCLMA_A0050	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VCLMA_A0051	COG0009	L-threonylcarbamoyladenylate synthase
VCLMA_A0052	COG0408	coproporphyrinogen oxidase activity
VCLMA_A0053	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VCLMA_A0055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VCLMA_A0056	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VCLMA_A0057	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VCLMA_A0059	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCLMA_A0060	COG2104	thiamine diphosphate biosynthetic process
VCLMA_A0061	COG2022	thiamine diphosphate biosynthetic process
VCLMA_A0062	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCLMA_A0063	COG0006	proline dipeptidase activity
VCLMA_A0063	COG0006	proline dipeptidase activity
VCLMA_A0067	COG1522	sequence-specific DNA binding
VCLMA_A0068	COG5001	Diguanylate cyclase
VCLMA_A0068	COG5002	protein histidine kinase activity
VCLMA_A0069	COG0742	ribosomal rna small subunit methyltransferase
VCLMA_A0071	COG0697	spore germination
VCLMA_A0072	COG0589	response to stress
VCLMA_A0073	COG1528	Iron-storage protein
VCLMA_A0075	COG2081	HI0933 family
VCLMA_A0077	COG1322	Protein conserved in bacteria
VCLMA_A0078	COG2226	methyltransferase
VCLMA_A0080	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
VCLMA_A0081	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCLMA_A0082	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCLMA_A0083	COG0805	protein transport
VCLMA_A0084	COG1858	cytochrome C peroxidase
VCLMA_A0085	COG0534	Mate efflux family protein
VCLMA_A0087	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VCLMA_A0088	COG2937	Belongs to the GPAT DAPAT family
VCLMA_A0089	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VCLMA_A0090	COG3161	chorismate lyase activity
VCLMA_A0091	COG1580	Controls the rotational direction of flagella during chemotaxis
VCLMA_A0092	COG0840	transmembrane signaling receptor activity
VCLMA_A0094	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCLMA_A0095	COG0084	hydrolase, TatD family'
VCLMA_A0100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCLMA_A0100	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCLMA_A0104	COG3078	GTPase activator activity
VCLMA_A0106	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VCLMA_A0107	COG3071	HemY protein
VCLMA_A0108	COG2959	enzyme of heme biosynthesis
VCLMA_A0109	COG1587	Uroporphyrinogen-III synthase
VCLMA_A0110	COG0181	hydroxymethylbilane synthase activity
VCLMA_A0112	COG3072	Adenylate cyclase
VCLMA_A0113	COG1965	Belongs to the frataxin family
VCLMA_A0115	COG0019	diaminopimelate decarboxylase activity
VCLMA_A0116	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VCLMA_A0118	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VCLMA_A0119	COG1011	Hydrolase
VCLMA_A0120	COG2200	EAL domain
VCLMA_A0120	COG3287	FIST C domain
VCLMA_A0120	COG2199	diguanylate cyclase activity
VCLMA_A0123	COG0561	phosphatase activity
VCLMA_A0124	COG2267	carboxylic ester hydrolase activity
VCLMA_A0125	COG1280	lysine exporter protein (LysE YggA)
VCLMA_A0126	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCLMA_A0127	COG0783	Belongs to the Dps family
VCLMA_A0133	COG0742	ribosomal rna small subunit methyltransferase
VCLMA_A0134	COG0552	protein localization to endoplasmic reticulum
VCLMA_A0135	COG2884	Cell division ATP-binding protein ftsE
VCLMA_A0136	COG2177	Part of the ABC transporter FtsEX involved in
VCLMA_A0137	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCLMA_A0138	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCLMA_A0141	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCLMA_A0142	COG1404	Belongs to the peptidase S8 family
VCLMA_A0143	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
VCLMA_A0145	COG0583	DNA-binding transcription factor activity
VCLMA_A0146	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VCLMA_A0147	COG2960	long-chain fatty acid transporting porin activity
VCLMA_A0148	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCLMA_A0149	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCLMA_A0150	COG1309	transcriptional regulator
VCLMA_A0155	COG0747	negative chemotaxis
VCLMA_A0157	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCLMA_A0159	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCLMA_A0160	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VCLMA_A0162	COG0210	DNA helicase
VCLMA_A0163	COG1280	lysine exporter protein (LysE YggA)
VCLMA_A0165	COG0405	Gamma-glutamyltransferase
VCLMA_A0166	COG2962	Rard protein
VCLMA_A0168	COG0514	ATP-dependent DNA helicase (RecQ)
VCLMA_A0172	COG4774	siderophore transport
VCLMA_A0173	COG1120	ATPase activity
VCLMA_A0177	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCLMA_A0178	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCLMA_A0178	COG1263	PTS System
VCLMA_A0180	COG1561	YicC-like family, N-terminal region
VCLMA_A0181	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VCLMA_A0182	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VCLMA_A0183	COG1560	Kdo2-lipid A biosynthetic process
VCLMA_A0185	COG1309	transcriptional regulator
VCLMA_A0187	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VCLMA_A0190	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VCLMA_A0191	COG0267	Belongs to the bacterial ribosomal protein bL33 family
VCLMA_A0193	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VCLMA_A0194	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VCLMA_A0195	COG0859	PFAM glycosyl transferase family 9
VCLMA_A0196	COG0463	Glycosyl transferase, family 2
VCLMA_A0197	COG0859	PFAM glycosyl transferase family 9
VCLMA_A0198	COG3642	lipopolysaccharide core region biosynthetic process
VCLMA_A0204	COG1519	Transferase
VCLMA_A0211	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCLMA_A0212	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
VCLMA_A0212	COG0662	Cupin 2, conserved barrel domain protein
VCLMA_A0213	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCLMA_A0214	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
VCLMA_A0220	COG0318	PFAM AMP-dependent synthetase and ligase
VCLMA_A0221	COG1012	belongs to the aldehyde dehydrogenase family
VCLMA_A0221	COG1454	alcohol dehydrogenase
VCLMA_A0230	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VCLMA_A0231	COG0668	transmembrane transport
VCLMA_A0232	COG1573	uracil-dna glycosylase
VCLMA_A0234	COG3068	Protein conserved in bacteria
VCLMA_A0236	COG1940	carbohydrate kinase activity
VCLMA_A0237	COG1253	flavin adenine dinucleotide binding
VCLMA_A0238	COG0776	regulation of translation
VCLMA_A0240	COG0151	Belongs to the GarS family
VCLMA_A0241	COG0138	bifunctional purine biosynthesis protein purh
VCLMA_A0243	COG0789	Transcriptional regulator
VCLMA_A0244	COG3710	Transcriptional regulator
VCLMA_A0245	COG0531	amino acid
VCLMA_A0246	COG1982	Orn Lys Arg decarboxylase major
VCLMA_A0247	COG0840	transmembrane signaling receptor activity
VCLMA_A0251	COG0800	Aldolase
VCLMA_A0252	COG2610	gluconate transmembrane transporter activity
VCLMA_A0253	COG3265	gluconokinase activity
VCLMA_A0254	COG0129	dihydroxy-acid dehydratase activity
VCLMA_A0255	COG1609	Transcriptional regulator
VCLMA_A0256	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VCLMA_A0257	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCLMA_A0258	COG2264	protein methyltransferase activity
VCLMA_A0259	COG0439	Biotin carboxylase
VCLMA_A0260	COG0511	ligase activity, forming carbon-carbon bonds
VCLMA_A0261	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VCLMA_A0262	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCLMA_A0265	COG2814	Major facilitator Superfamily
VCLMA_A0266	COG0784	Response regulator, receiver
VCLMA_A0266	COG2205	protein histidine kinase activity
VCLMA_A0267	COG0248	Ppx GppA phosphatase
VCLMA_A0268	COG0513	Belongs to the DEAD box helicase family
VCLMA_A0269	COG3118	belongs to the thioredoxin family
VCLMA_A0270	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
VCLMA_A0272	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VCLMA_A0275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VCLMA_A0277	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VCLMA_A0279	COG1072	(Pantothenic acid kinase))
VCLMA_A0280	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCLMA_A0281	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCLMA_A0282	COG0250	Participates in transcription elongation, termination and antitermination
VCLMA_A0283	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VCLMA_A0284	COG0081	regulation of translation
VCLMA_A0285	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VCLMA_A0286	COG0222	ribosome binding
VCLMA_A0289	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VCLMA_A0290	COG2816	NAD+ diphosphatase activity
VCLMA_A0291	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VCLMA_A0294	COG4942	peptidase
VCLMA_A0295	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VCLMA_A0297	COG0471	metal ion transport
VCLMA_A0298	COG0688	phosphatidylethanolamine metabolic process
VCLMA_A0299	COG1162	GTPase activity
VCLMA_A0301	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VCLMA_A0302	COG0802	atpase or kinase
VCLMA_A0305	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VCLMA_A0306	COG1923	regulation of RNA biosynthetic process
VCLMA_A0307	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VCLMA_A0309	COG0330	HflC and HflK could
VCLMA_A0310	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VCLMA_A0311	COG2900	Belongs to the SlyX family
VCLMA_A0314	COG2964	Protein conserved in bacteria
VCLMA_A0315	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VCLMA_A0316	COG2923	Belongs to the DsrF TusC family
VCLMA_A0318	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
VCLMA_A0319	COG0049	tRNA binding
VCLMA_A0320	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCLMA_A0321	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCLMA_A0322	COG2906	2 iron, 2 sulfur cluster binding
VCLMA_A0325	COG2965	DNA replication, synthesis of RNA primer
VCLMA_A0326	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
VCLMA_A0327	COG0359	binds to the 23S rRNA
VCLMA_A0329	COG0305	Participates in initiation and elongation during chromosome replication
VCLMA_A0330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCLMA_A0332	COG0432	Pfam Uncharacterised protein family UPF0047
VCLMA_A0333	COG0166	Belongs to the GPI family
VCLMA_A0336	COG0735	belongs to the Fur family
VCLMA_A0337	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCLMA_A0343	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCLMA_A0344	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VCLMA_A0345	COG0175	sulfate reduction
VCLMA_A0348	COG1410	methionine synthase
VCLMA_A0348	COG0646	methionine synthase
VCLMA_A0349	COG0527	aspartate kinase activity
VCLMA_A0350	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCLMA_A0352	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VCLMA_A0355	COG0629	single-stranded DNA binding
VCLMA_A0361	COG3267	Type II secretory pathway component ExeA
VCLMA_A0361	COG3409	Peptidoglycan-binding domain 1 protein
VCLMA_A0363	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCLMA_A0364	COG1459	type II secretion system
VCLMA_A0373	COG1077	Cell shape determining protein MreB Mrl
VCLMA_A0374	COG1792	Involved in formation and maintenance of cell shape
VCLMA_A0375	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VCLMA_A0376	COG0424	maF-like protein
VCLMA_A0377	COG1530	ribonuclease E activity
VCLMA_A0378	COG3164	Protein of unknown function
VCLMA_A0379	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VCLMA_A0381	COG2235	arginine
VCLMA_A0386	COG0589	response to stress
VCLMA_A0389	COG1438	arginine binding
VCLMA_A0390	COG0039	L-malate dehydrogenase activity
VCLMA_A0391	COG0531	amino acid
VCLMA_A0392	COG0142	geranyltranstransferase activity
VCLMA_A0393	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VCLMA_A0394	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VCLMA_A0395	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VCLMA_A0396	COG2966	Psort location CytoplasmicMembrane, score
VCLMA_A0397	COG3610	response to peptide
VCLMA_A0399	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VCLMA_A0400	COG2967	ApaG domain
VCLMA_A0401	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VCLMA_A0402	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VCLMA_A0405	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VCLMA_A0407	COG0741	lytic transglycosylase activity
VCLMA_A0408	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VCLMA_A0409	COG1194	a g-specific adenine glycosylase
VCLMA_A0410	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VCLMA_A0411	COG2066	Belongs to the glutaminase family
VCLMA_A0413	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VCLMA_A0414	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VCLMA_A0416	COG1872	DUF167
VCLMA_A0417	COG0762	integral membrane protein
VCLMA_A0418	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VCLMA_A0419	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VCLMA_A0423	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCLMA_A0424	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VCLMA_A0425	COG1678	Uncharacterized ACR, COG1678
VCLMA_A0426	COG0189	ligase activity
VCLMA_A0427	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VCLMA_A0428	COG2356	endonuclease I
VCLMA_A0429	COG3091	SprT-like family
VCLMA_A0430	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VCLMA_A0432	COG0583	DNA-binding transcription factor activity
VCLMA_A0434	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCLMA_A0435	COG0126	phosphoglycerate kinase activity
VCLMA_A0436	COG0191	fructose-bisphosphate aldolase activity
VCLMA_A0437	COG0668	transmembrane transport
VCLMA_A0438	COG1279	arginine transmembrane transporter activity
VCLMA_A0439	COG0583	DNA-binding transcription factor activity
VCLMA_A0442	COG0469	pyruvate kinase activity
VCLMA_A0443	COG1349	DNA-binding transcription factor activity
VCLMA_A0444	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VCLMA_A0445	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCLMA_A0449	COG1610	YqeY-like protein
VCLMA_A0450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VCLMA_A0454	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VCLMA_A0455	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VCLMA_A0456	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCLMA_A0457	COG1968	undecaprenyl-diphosphatase activity
VCLMA_A0458	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VCLMA_A0459	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VCLMA_A0460	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VCLMA_A0461	COG0585	pseudouridine synthase activity
VCLMA_A0462	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VCLMA_A0463	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VCLMA_A0464	COG4942	peptidase
VCLMA_A0464	COG1388	LysM domain
VCLMA_A0465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCLMA_A0466	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VCLMA_A0470	COG4208	sulfate ABC transporter
VCLMA_A0473	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VCLMA_A0474	COG2137	regulation of response to DNA damage stimulus
VCLMA_A0475	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VCLMA_A0477	COG0527	aspartate kinase activity
VCLMA_A0478	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
VCLMA_A0481	COG1238	metal cluster binding
VCLMA_A0482	COG0612	Peptidase, M16
VCLMA_A0483	COG2918	glutathione biosynthetic process
VCLMA_A0484	COG1854	S-ribosylhomocysteine lyase activity
VCLMA_A0485	COG4536	flavin adenine dinucleotide binding
VCLMA_A0487	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VCLMA_A0488	COG0228	four-way junction DNA binding
VCLMA_A0490	COG0336	Belongs to the RNA methyltransferase TrmD family
VCLMA_A0491	COG0335	large ribosomal subunit rRNA binding
VCLMA_A0492	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCLMA_A0495	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VCLMA_A0496	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VCLMA_A0497	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VCLMA_A0498	COG0723	plastoquinol--plastocyanin reductase activity
VCLMA_A0499	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VCLMA_A0501	COG0625	glutathione transferase activity
VCLMA_A0502	COG2969	positive regulation of protein catabolic process
VCLMA_A0503	COG2823	Periplasmic or secreted lipoprotein
VCLMA_A0504	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCLMA_A0505	COG0792	nuclease activity
VCLMA_A0506	COG3107	peptidoglycan biosynthetic process
VCLMA_A0507	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VCLMA_A0510	COG0288	reversible hydration of carbon dioxide
VCLMA_A0512	COG1131	(ABC) transporter
VCLMA_A0513	COG0842	Transport permease protein
VCLMA_A0514	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VCLMA_A0515	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VCLMA_A0516	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCLMA_A0518	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCLMA_A0519	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VCLMA_A0520	COG1489	DNA binding
VCLMA_A0522	COG1643	Atp-dependent helicase
VCLMA_A0523	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VCLMA_A0524	COG1752	Esterase of the alpha-beta hydrolase superfamily
VCLMA_A0525	COG1049	propionate catabolic process, 2-methylcitrate cycle
VCLMA_A0526	COG3112	Uncharacterised protein family (UPF0231)
VCLMA_A0527	COG0347	Belongs to the P(II) protein family
VCLMA_A0528	COG0004	ammonium transporteR
VCLMA_A0529	COG1840	ABC-type Fe3 transport system, periplasmic component
VCLMA_A0531	COG3842	ATPase activity
VCLMA_A0535	COG2971	BadF BadG BcrA BcrD
VCLMA_A0537	COG4608	Belongs to the ABC transporter superfamily
VCLMA_A0538	COG0444	Belongs to the ABC transporter superfamily
VCLMA_A0539	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCLMA_A0541	COG0747	negative chemotaxis
VCLMA_A0543	COG2813	Specifically methylates the guanine in position
VCLMA_A0544	COG0628	permease
VCLMA_A0546	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VCLMA_A0548	COG0316	Belongs to the HesB IscA family
VCLMA_A0551	COG0739	heme binding
VCLMA_A0552	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCLMA_A0553	COG2027	D-alanyl-D-alanine carboxypeptidase
VCLMA_A0555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCLMA_A0556	COG1534	Rna-binding protein
VCLMA_A0558	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VCLMA_A0559	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VCLMA_A0560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCLMA_A0561	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCLMA_A0562	COG0779	Required for maturation of 30S ribosomal subunits
VCLMA_A0563	COG0195	Participates in both transcription termination and antitermination
VCLMA_A0565	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VCLMA_A0566	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
VCLMA_A0567	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VCLMA_A0569	COG4785	May be involved in cell division
VCLMA_A0576	COG3153	acetyltransferase
VCLMA_A0581	COG0513	Belongs to the DEAD box helicase family
VCLMA_A0582	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
VCLMA_A0584	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VCLMA_A0585	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VCLMA_A0586	COG2204	response regulator
VCLMA_A0590	COG0667	Aldo Keto reductase
VCLMA_A0591	COG3066	DNA modification
VCLMA_A0593	COG0494	nUDIX hydrolase
VCLMA_A0594	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
VCLMA_A0595	COG0730	response to heat
VCLMA_A0596	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VCLMA_A0597	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
VCLMA_A0598	COG1283	sodium-dependent phosphate transmembrane transporter activity
VCLMA_A0599	COG0583	DNA-binding transcription factor activity
VCLMA_A0600	COG0640	Transcriptional regulator
VCLMA_A0601	COG0268	Binds directly to 16S ribosomal RNA
VCLMA_A0602	COG0728	peptidoglycan biosynthetic process
VCLMA_A0603	COG0196	riboflavin kinase activity
VCLMA_A0604	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
VCLMA_A0605	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VCLMA_A0606	COG1047	Peptidyl-prolyl cis-trans
VCLMA_A0607	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VCLMA_A0608	COG1966	Carbon starvation protein
VCLMA_A0610	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCLMA_A0611	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VCLMA_A0612	COG1472	Belongs to the glycosyl hydrolase 3 family
VCLMA_A0613	COG3279	Response regulator of the LytR AlgR family
VCLMA_A0614	COG3275	phosphorelay sensor kinase activity
VCLMA_A0615	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCLMA_A0616	COG0287	Prephenate dehydrogenase
VCLMA_A0616	COG1605	Chorismate mutase
VCLMA_A0618	COG0488	(ABC) transporter
VCLMA_A0620	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VCLMA_A0621	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
VCLMA_A0622	COG5001	Diguanylate cyclase
VCLMA_A0623	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCLMA_A0624	COG1605	Chorismate mutase
VCLMA_A0624	COG0077	Prephenate dehydratase
VCLMA_A0625	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCLMA_A0627	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCLMA_A0628	COG0564	pseudouridine synthase activity
VCLMA_A0633	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCLMA_A0635	COG2974	May be involved in recombination
VCLMA_A0636	COG0745	RESPONSE REGULATOR receiver
VCLMA_A0637	COG5002	protein histidine kinase activity
VCLMA_A0639	COG0248	Ppx GppA phosphatase
VCLMA_A0640	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VCLMA_A0642	COG0581	inorganic phosphate transmembrane transporter activity
VCLMA_A0643	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCLMA_A0646	COG3142	Participates in the control of copper homeostasis
VCLMA_A0647	COG0450	alkyl hydroperoxide reductase
VCLMA_A0648	COG0583	DNA-binding transcription factor activity
VCLMA_A0651	COG0517	IMP dehydrogenase activity
VCLMA_A0652	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
VCLMA_A0653	COG0343	queuine tRNA-ribosyltransferase activity
VCLMA_A0654	COG1862	Preprotein translocase
VCLMA_A0655	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCLMA_A0656	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCLMA_A0657	COG0483	inositol monophosphate 1-phosphatase activity
VCLMA_A0661	COG0822	iron-sulfur transferase activity
VCLMA_A0665	COG0633	Ferredoxin
VCLMA_A0666	COG2975	iron-sulfur cluster assembly
VCLMA_A0667	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCLMA_A0668	COG0105	UTP biosynthetic process
VCLMA_A0671	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VCLMA_A0673	COG2976	Protein conserved in bacteria
VCLMA_A0674	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCLMA_A0675	COG1160	GTP binding
VCLMA_A0678	COG1570	exodeoxyribonuclease VII activity
VCLMA_A0679	COG0516	GMP reductase activity
VCLMA_A0679	COG0517	IMP dehydrogenase activity
VCLMA_A0680	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VCLMA_A0680	COG0519	Catalyzes the synthesis of GMP from XMP
VCLMA_A0682	COG1584	GPR1 FUN34 yaaH family protein
VCLMA_A0683	COG1535	isochorismatase
VCLMA_A0683	COG3433	isochorismatase activity
VCLMA_A0684	COG1021	2,3-dihydroxybenzoate-AMP ligase
VCLMA_A0685	COG1169	isochorismate synthase
VCLMA_A0686	COG1028	Short-chain dehydrogenase reductase Sdr
VCLMA_A0688	COG4592	Periplasmic binding protein
VCLMA_A0689	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCLMA_A0690	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCLMA_A0691	COG1120	ATPase activity
VCLMA_A0692	COG2977	Belongs to the P-Pant transferase superfamily
VCLMA_A0693	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCLMA_A0694	COG1120	ATPase activity
VCLMA_A0695	COG2977	Belongs to the P-Pant transferase superfamily
VCLMA_A0696	COG1115	amino acid carrier protein
VCLMA_A0698	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VCLMA_A0699	COG0583	DNA-binding transcription factor activity
VCLMA_A0702	COG4565	transcriptional regulatory protein
VCLMA_A0704	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCLMA_A0705	COG5016	pyruvate
VCLMA_A0705	COG0511	ligase activity, forming carbon-carbon bonds
VCLMA_A0706	COG3630	sodium ion export across plasma membrane
VCLMA_A0709	COG3052	prosthetic group binding
VCLMA_A0710	COG2301	Belongs to the HpcH HpaI aldolase family
VCLMA_A0711	COG3051	citrate lyase alpha subunit
VCLMA_A0712	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
VCLMA_A0715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCLMA_A0716	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VCLMA_A0717	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VCLMA_A0719	COG1061	Type III restriction enzyme res subunit
VCLMA_A0724	COG0582	viral genome integration into host DNA
VCLMA_A0725	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VCLMA_A0726	COG2867	negative regulation of translational initiation
VCLMA_A0727	COG2914	Belongs to the UPF0125 (RnfH) family
VCLMA_A0728	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCLMA_A0730	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VCLMA_A0731	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VCLMA_A0732	COG0443	Heat shock 70 kDa protein
VCLMA_A0733	COG0484	heat shock protein binding
VCLMA_A0739	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCLMA_A0740	COG0590	tRNA wobble adenosine to inosine editing
VCLMA_A0742	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VCLMA_A0745	COG0047	phosphoribosylformylglycinamidine synthase activity
VCLMA_A0745	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VCLMA_A0749	COG0442	prolyl-tRNA aminoacylation
VCLMA_A0750	COG1720	tRNA m6t6A37 methyltransferase activity
VCLMA_A0751	COG0254	rRNA binding
VCLMA_A0752	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCLMA_A0754	COG1671	Belongs to the UPF0178 family
VCLMA_A0756	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCLMA_A0758	COG3098	single-species biofilm formation
VCLMA_A0759	COG0564	pseudouridine synthase activity
VCLMA_A0760	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VCLMA_A0761	COG0142	geranyltranstransferase activity
VCLMA_A0762	COG1722	exodeoxyribonuclease VII activity
VCLMA_A0763	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VCLMA_A0765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCLMA_A0765	COG0301	tRNA thio-modification
VCLMA_A0766	COG0583	DNA-binding transcription factor activity
VCLMA_A0767	COG2363	Small membrane protein
VCLMA_A0768	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCLMA_A0769	COG1611	Belongs to the LOG family
VCLMA_A0770	COG3706	GGDEF domain
VCLMA_A0772	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCLMA_A0772	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCLMA_A0774	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VCLMA_A0775	COG1464	Belongs to the NlpA lipoprotein family
VCLMA_A0776	COG2011	ABC-type metal ion transport system permease component
VCLMA_A0777	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VCLMA_A0778	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCLMA_A0779	COG1609	Transcriptional regulator
VCLMA_A0781	COG1263	PTS System
VCLMA_A0781	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCLMA_A0782	COG0366	Alpha amylase catalytic
VCLMA_A0785	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VCLMA_A0786	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VCLMA_A0790	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
VCLMA_A0796	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCLMA_A0798	COG1596	polysaccharide export
VCLMA_A0803	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCLMA_A0805	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VCLMA_A0806	COG0321	lipoyl(octanoyl) transferase activity
VCLMA_A0807	COG2921	Belongs to the UPF0250 family
VCLMA_A0808	COG1686	Belongs to the peptidase S11 family
VCLMA_A0809	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCLMA_A0810	COG0772	Belongs to the SEDS family
VCLMA_A0811	COG0768	penicillin binding
VCLMA_A0812	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VCLMA_A0813	COG0799	negative regulation of ribosome biogenesis
VCLMA_A0814	COG1466	dna polymerase III delta subunit
VCLMA_A0815	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VCLMA_A0816	COG0495	leucyl-tRNA aminoacylation
VCLMA_A0817	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VCLMA_A0818	COG4535	Mg2 and Co2 transporter CorC
VCLMA_A0819	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VCLMA_A0821	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCLMA_A0822	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCLMA_A0823	COG2190	(PTS) system
VCLMA_A0825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCLMA_A0826	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VCLMA_A0827	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VCLMA_A0828	COG3115	cell septum assembly
VCLMA_A0829	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VCLMA_A0832	COG0789	Transcriptional regulator
VCLMA_A0833	COG1585	Membrane protein implicated in regulation of membrane protease activity
VCLMA_A0834	COG0330	HflC and HflK could
VCLMA_A0835	COG3118	belongs to the thioredoxin family
VCLMA_A0837	COG0300	oxidoreductase activity
VCLMA_A0839	COG0622	Phosphoesterase
VCLMA_A0842	COG3710	Transcriptional regulator
VCLMA_A0843	COG0326	Molecular chaperone. Has ATPase activity
VCLMA_A0844	COG0563	adenylate kinase activity
VCLMA_A0845	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VCLMA_A0849	COG0367	asparagine synthase
VCLMA_A0850	COG4651	solute:proton antiporter activity
VCLMA_A0850	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCLMA_A0851	COG1940	carbohydrate kinase activity
VCLMA_A0851	COG1846	Transcriptional regulator
VCLMA_A0853	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCLMA_A0853	COG2190	(PTS) system
VCLMA_A0853	COG1263	PTS System
VCLMA_A0854	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCLMA_A0856	COG0101	tRNA pseudouridine synthase activity
VCLMA_A0857	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VCLMA_A0858	COG0285	dihydrofolate synthase activity
VCLMA_A0859	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VCLMA_A0860	COG1286	toxin biosynthetic process
VCLMA_A0861	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VCLMA_A0862	COG2056	Na+-H+ antiporter family
VCLMA_A0863	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VCLMA_A0867	COG0346	lactoylglutathione lyase activity
VCLMA_A0868	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VCLMA_A0869	COG4660	Part of a membrane complex involved in electron transport
VCLMA_A0870	COG4659	FMN binding
VCLMA_A0872	COG4656	Part of a membrane complex involved in electron transport
VCLMA_A0873	COG2878	Part of a membrane complex involved in electron transport
VCLMA_A0874	COG4657	Part of a membrane complex involved in electron transport
VCLMA_A0876	COG0556	nucleotide-excision repair
VCLMA_A0877	COG2204	response regulator
VCLMA_A0878	COG2198	Histidine kinase
VCLMA_A0879	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VCLMA_A0880	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VCLMA_A0882	COG0315	cyclic pyranopterin monophosphate synthase activity
VCLMA_A0883	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VCLMA_A0884	COG0314	molybdopterin synthase activity
VCLMA_A0886	COG0517	IMP dehydrogenase activity
VCLMA_A0889	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCLMA_A0891	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCLMA_A0891	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCLMA_A0893	COG0572	uridine kinase
VCLMA_A0894	COG2982	Protein involved in outer membrane biogenesis
VCLMA_A0895	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VCLMA_A0898	COG2067	long-chain fatty acid transport protein
VCLMA_A0899	COG2067	long-chain fatty acid transport protein
VCLMA_A0902	COG0183	Belongs to the thiolase family
VCLMA_A0903	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCLMA_A0903	COG1024	Enoyl-CoA hydratase
VCLMA_A0904	COG0778	Nitroreductase
VCLMA_A0906	COG0745	RESPONSE REGULATOR receiver
VCLMA_A0909	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VCLMA_A0911	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VCLMA_A0912	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VCLMA_A0915	COG1028	Short-chain dehydrogenase reductase Sdr
VCLMA_A0916	COG0616	signal peptide processing
VCLMA_A0918	COG1522	sequence-specific DNA binding
VCLMA_A0919	COG1946	Acyl-CoA thioesterase
VCLMA_A0923	COG3706	GGDEF domain
VCLMA_A0924	COG0640	Transcriptional regulator
VCLMA_A0925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCLMA_A0930	COG1881	PFAM PEBP family protein
VCLMA_A0934	COG0009	L-threonylcarbamoyladenylate synthase
VCLMA_A0937	COG2201	protein-glutamate methylesterase activity
VCLMA_A0939	COG5002	protein histidine kinase activity
VCLMA_A0940	COG4191	Histidine kinase
VCLMA_A0941	COG5001	Diguanylate cyclase
VCLMA_A0941	COG3300	MHYT domain
VCLMA_A0942	COG2204	response regulator
VCLMA_A0946	COG0601	transmembrane transport
VCLMA_A0947	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCLMA_A0948	COG0444	Belongs to the ABC transporter superfamily
VCLMA_A0949	COG4608	Belongs to the ABC transporter superfamily
VCLMA_A0950	COG0435	Glutathione S-transferase
VCLMA_A0954	COG4628	conserved protein (DUF2132)
VCLMA_A0956	COG4120	Belongs to the binding-protein-dependent transport system permease family
VCLMA_A0958	COG2199	diguanylate cyclase activity
VCLMA_A0958	COG2203	Gaf domain
VCLMA_A0959	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCLMA_A0960	COG0653	protein targeting
VCLMA_A0961	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VCLMA_A0962	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VCLMA_A0963	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VCLMA_A0966	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCLMA_A0967	COG0156	8-amino-7-oxononanoate synthase activity
VCLMA_A0968	COG2226	methyltransferase
VCLMA_A0969	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VCLMA_A0971	COG0501	Belongs to the peptidase M48B family
VCLMA_A0973	COG0300	oxidoreductase activity
VCLMA_A0976	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VCLMA_A0978	COG2268	Band 7 protein
VCLMA_A0980	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VCLMA_A0981	COG2915	High frequency lysogenization protein hflD homolog
VCLMA_A0982	COG0482	sulfurtransferase activity
VCLMA_A0983	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCLMA_A0984	COG2916	Histone family protein nucleoid-structuring protein H-NS
VCLMA_A0986	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VCLMA_A0987	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VCLMA_A0988	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VCLMA_A0989	COG0131	Imidazoleglycerol-phosphate dehydratase
VCLMA_A0989	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCLMA_A0990	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VCLMA_A0991	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VCLMA_A0992	COG0107	imidazoleglycerol-phosphate synthase activity
VCLMA_A0993	COG0140	phosphoribosyl-ATP diphosphatase activity
VCLMA_A0993	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VCLMA_A0994	COG1187	pseudouridine synthase activity
VCLMA_A0996	COG1278	Cold shock
VCLMA_A0997	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VCLMA_A0998	COG0542	response to heat
VCLMA_A1000	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCLMA_A1001	COG1979	alcohol dehydrogenase
VCLMA_A1002	COG1737	Transcriptional regulator
VCLMA_A1003	COG0076	glutamate decarboxylase activity
VCLMA_A1005	COG2431	L-lysine efflux transmembrane transporter activity
VCLMA_A1007	COG3070	regulator of competence-specific genes
VCLMA_A1010	COG3852	Histidine kinase
VCLMA_A1012	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VCLMA_A1015	COG4067	protein conserved in archaea
VCLMA_A1015	COG0189	ligase activity
VCLMA_A1016	COG0500	methyltransferase
VCLMA_A1017	COG4106	trans-aconitate 2-methyltransferase activity
VCLMA_A1018	COG1801	Protein of unknown function DUF72
VCLMA_A1019	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VCLMA_A1020	COG1435	thymidine kinase activity
VCLMA_A1021	COG1301	dicarboxylic acid transport
VCLMA_A1022	COG0159	tryptophan synthase activity
VCLMA_A1023	COG0133	tryptophan synthase activity
VCLMA_A1024	COG0135	phosphoribosylanthranilate isomerase activity
VCLMA_A1024	COG0134	indole-3-glycerol-phosphate synthase activity
VCLMA_A1026	COG0512	Glutamine amidotransferase of anthranilate synthase
VCLMA_A1027	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCLMA_A1029	COG0613	PHP domain protein
VCLMA_A1030	COG0009	L-threonylcarbamoyladenylate synthase
VCLMA_A1031	COG1187	pseudouridine synthase activity
VCLMA_A1032	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VCLMA_A1034	COG0492	ferredoxin-NADP+ reductase activity
VCLMA_A1036	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCLMA_A1037	COG3706	GGDEF domain
VCLMA_A1038	COG2949	membrane
VCLMA_A1040	COG0281	malic enzyme
VCLMA_A1046	COG2885	chlorophyll binding
VCLMA_A1053	COG2986	histidine ammonia-lyase
VCLMA_A1054	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VCLMA_A1055	COG0010	Belongs to the arginase family
VCLMA_A1056	COG1228	amidohydrolase
VCLMA_A1060	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCLMA_A1062	COG5001	Diguanylate cyclase
VCLMA_A1063	COG0417	DNA replication proofreading
VCLMA_A1064	COG2197	response regulator
VCLMA_A1065	COG0322	excinuclease ABC activity
VCLMA_A1067	COG0745	RESPONSE REGULATOR receiver
VCLMA_A1067	COG3706	GGDEF domain
VCLMA_A1070	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VCLMA_A1071	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCLMA_A1071	COG0072	phenylalanine-tRNA ligase activity
VCLMA_A1072	COG0776	regulation of translation
VCLMA_A1074	COG0500	methyltransferase
VCLMA_A1075	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
VCLMA_A1077	COG0295	cytidine deaminase activity
VCLMA_A1078	COG1346	cytolysis
VCLMA_A1080	COG2925	Exonuclease
VCLMA_A1082	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCLMA_A1084	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VCLMA_A1085	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VCLMA_A1088	COG2988	succinylglutamate desuccinylase activity
VCLMA_A1089	COG4139	cobalamin transport
VCLMA_A1090	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
VCLMA_A1099	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCLMA_A1100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCLMA_A1101	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCLMA_A1105	COG2814	Major facilitator Superfamily
VCLMA_A1107	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VCLMA_A1113	COG3108	Peptidase M15
VCLMA_A1114	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCLMA_A1122	COG1846	Transcriptional regulator
VCLMA_A1123	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VCLMA_A1124	COG0726	polysaccharide deacetylase
VCLMA_A1125	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VCLMA_A1127	COG1447	Phosphotransferase system cellobiose-specific component IIA
VCLMA_A1128	COG1486	melibiose metabolic process
VCLMA_A1129	COG3394	polysaccharide catabolic process
VCLMA_A1130	COG1609	Transcriptional regulator
VCLMA_A1131	COG2943	transferase activity, transferring hexosyl groups
VCLMA_A1132	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
VCLMA_A1133	COG0840	transmembrane signaling receptor activity
VCLMA_A1136	COG1448	Aminotransferase
VCLMA_A1137	COG3437	response regulator, receiver
VCLMA_A1137	COG2770	Histidine kinase
VCLMA_A1138	COG0351	phosphomethylpyrimidine kinase
VCLMA_A1139	COG0017	Asparaginyl-tRNA synthetase
VCLMA_A1141	COG0720	synthase
VCLMA_A1142	COG1760	l-serine dehydratase
VCLMA_A1143	COG0814	amino acid
VCLMA_A1144	COG0494	nUDIX hydrolase
VCLMA_A1145	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCLMA_A1148	COG3106	COG3106 Predicted ATPase
VCLMA_A1149	COG3768	UPF0283 membrane protein
VCLMA_A1150	COG3283	Transcriptional regulator of aromatic amino acids metabolism
VCLMA_A1151	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCLMA_A1156	COG0471	metal ion transport
VCLMA_A1157	COG4191	Histidine kinase
VCLMA_A1157	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCLMA_A1159	COG2990	Protein conserved in bacteria
VCLMA_A1160	COG3713	MltA-interacting MipA family protein
VCLMA_A1161	COG5002	protein histidine kinase activity
VCLMA_A1162	COG0745	RESPONSE REGULATOR receiver
VCLMA_A1175	COG2186	Transcriptional regulator
VCLMA_A1176	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VCLMA_A1182	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCLMA_A1186	COG0625	glutathione transferase activity
VCLMA_A1187	COG3437	response regulator, receiver
VCLMA_A1190	COG3706	GGDEF domain
VCLMA_A1191	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCLMA_A1192	COG1254	Belongs to the acylphosphatase family
VCLMA_A1193	COG2920	part of a sulfur-relay system
VCLMA_A1194	COG0670	Belongs to the BI1 family
VCLMA_A1195	COG1126	abc transporter atp-binding protein
VCLMA_A1196	COG0765	amino acid transport
VCLMA_A1197	COG4597	amino acid ABC transporter
VCLMA_A1198	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCLMA_A1200	COG0561	phosphatase activity
VCLMA_A1201	COG0602	queuosine metabolic process
VCLMA_A1202	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VCLMA_A1208	COG3706	GGDEF domain
VCLMA_A1210	COG0443	Heat shock 70 kDa protein
VCLMA_A1218	COG1643	Atp-dependent helicase
VCLMA_A1220	COG0443	Heat shock 70 kDa protein
VCLMA_A1221	COG0095	Lipoate-protein ligase
VCLMA_A1223	COG0583	DNA-binding transcription factor activity
VCLMA_A1224	COG0477	Major facilitator Superfamily
VCLMA_A1225	COG0415	Belongs to the DNA photolyase family
VCLMA_A1226	COG2076	Multidrug Resistance protein
VCLMA_A1230	COG2198	Histidine kinase
VCLMA_A1230	COG0643	Histidine kinase
VCLMA_A1232	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCLMA_A1234	COG2201	protein-glutamate methylesterase activity
VCLMA_A1235	COG0835	chemotaxis
VCLMA_A1236	COG0840	transmembrane signaling receptor activity
VCLMA_A1239	COG0513	Belongs to the DEAD box helicase family
VCLMA_A1242	COG1566	PFAM secretion protein HlyD family protein
VCLMA_A1243	COG2814	Major facilitator Superfamily
VCLMA_A1245	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VCLMA_A1248	COG1280	lysine exporter protein (LysE YggA)
VCLMA_A1249	COG1115	amino acid carrier protein
VCLMA_A1252	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCLMA_A1253	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCLMA_A1254	COG1177	transmembrane transport
VCLMA_A1255	COG1176	ABC-type spermidine putrescine transport system, permease component I
VCLMA_A1256	COG3842	ATPase activity
VCLMA_A1259	COG0037	tRNA processing
VCLMA_A1260	COG0589	response to stress
VCLMA_A1261	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VCLMA_A1266	COG2010	Cytochrome c
VCLMA_A1269	COG3278	Belongs to the heme-copper respiratory oxidase family
VCLMA_A1271	COG2205	protein histidine kinase activity
VCLMA_A1271	COG0784	Response regulator, receiver
VCLMA_A1276	COG2994	toxin metabolic process
VCLMA_A1277	COG1073	alpha beta
VCLMA_A1277	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VCLMA_A1277	COG3064	Membrane
VCLMA_A1282	COG3120	sequence-specific DNA binding
VCLMA_A1283	COG1067	ATP-dependent peptidase activity
VCLMA_A1284	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCLMA_A1288	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCLMA_A1288	COG0116	Belongs to the methyltransferase superfamily
VCLMA_A1290	COG0167	dihydroorotate dehydrogenase activity
VCLMA_A1293	COG0308	aminopeptidase N
VCLMA_A1296	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VCLMA_A1297	COG1956	GAF domain-containing protein
VCLMA_A1298	COG1132	(ABC) transporter
VCLMA_A1299	COG2995	paraquat-inducible protein a
VCLMA_A1300	COG3008	intermembrane lipid transfer
VCLMA_A1301	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
VCLMA_A1301	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VCLMA_A1302	COG2996	Protein conserved in bacteria
VCLMA_A1305	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCLMA_A1307	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VCLMA_A1310	COG0437	4 iron, 4 sulfur cluster binding
VCLMA_A1317	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VCLMA_A1318	COG0488	(ABC) transporter
VCLMA_A1319	COG3852	Histidine kinase
VCLMA_A1320	COG2204	response regulator
VCLMA_A1322	COG4662	Binding-protein-dependent transport system inner membrane component
VCLMA_A1323	COG3842	ATPase activity
VCLMA_A1324	COG0746	molybdenum cofactor guanylyltransferase activity
VCLMA_A1325	COG0303	'Molybdopterin
VCLMA_A1328	COG1940	carbohydrate kinase activity
VCLMA_A1331	COG0840	transmembrane signaling receptor activity
VCLMA_A1332	COG0791	NLP P60 protein
VCLMA_A1336	COG0534	Mate efflux family protein
VCLMA_A1338	COG1793	dna ligase
VCLMA_A1340	COG0848	biopolymer transport protein
VCLMA_A1345	COG1175	transmembrane transport
VCLMA_A1346	COG0395	ABC-type sugar transport system, permease component
VCLMA_A1348	COG1349	DNA-binding transcription factor activity
VCLMA_A1349	COG0584	glycerophosphoryl diester phosphodiesterase
VCLMA_A1350	COG2731	YhcH YjgK YiaL family protein
VCLMA_A1351	COG0251	oxidation-reduction process
VCLMA_A1352	COG1609	Transcriptional regulator
VCLMA_A1353	COG2723	6-phospho-beta-galactosidase activity
VCLMA_A1354	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
VCLMA_A1359	COG0577	efflux transmembrane transporter activity
VCLMA_A1359	COG1136	(ABC) transporter
VCLMA_A1360	COG1136	(ABC) transporter
VCLMA_A1360	COG0577	efflux transmembrane transporter activity
VCLMA_A1361	COG1136	(ABC) transporter
VCLMA_A1361	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCLMA_A1362	COG1294	oxidase, subunit
VCLMA_A1363	COG1271	oxidase subunit
VCLMA_A1371	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCLMA_A1373	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCLMA_A1380	COG3527	Alpha-acetolactate decarboxylase
VCLMA_A1383	COG2200	EAL domain
VCLMA_A1383	COG2199	diguanylate cyclase activity
VCLMA_A1384	COG3706	GGDEF domain
VCLMA_A1385	COG2017	converts alpha-aldose to the beta-anomer
VCLMA_A1386	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VCLMA_A1387	COG1085	galactose-1-phosphate uridylyltransferase
VCLMA_A1390	COG3706	GGDEF domain
VCLMA_A1390	COG0745	RESPONSE REGULATOR receiver
VCLMA_A1393	COG0835	chemotaxis
VCLMA_A1393	COG0784	Response regulator, receiver
VCLMA_A1395	COG4565	transcriptional regulatory protein
VCLMA_A1396	COG3290	protein histidine kinase activity
VCLMA_A1398	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCLMA_A1402	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VCLMA_A1403	COG3063	Type IV pilus biogenesis stability protein PilW
VCLMA_A1406	COG1451	nucleotide metabolic process
VCLMA_A1411	COG1538	Outer membrane efflux protein
VCLMA_A1413	COG0019	diaminopimelate decarboxylase activity
VCLMA_A1414	COG1748	Saccharopine dehydrogenase
VCLMA_A1416	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCLMA_A1419	COG1136	(ABC) transporter
VCLMA_A1420	COG0534	Mate efflux family protein
VCLMA_A1421	COG0702	epimerase
VCLMA_A1423	COG2814	Major facilitator Superfamily
VCLMA_A1424	COG1187	pseudouridine synthase activity
VCLMA_A1425	COG1061	Type III restriction enzyme res subunit
VCLMA_A1428	COG5002	protein histidine kinase activity
VCLMA_A1429	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VCLMA_A1430	COG3706	GGDEF domain
VCLMA_A1430	COG4251	negative regulation of phosphorylation
VCLMA_A1430	COG2203	Gaf domain
VCLMA_A1430	COG5001	Diguanylate cyclase
VCLMA_A1438	COG4934	collagen metabolic process
VCLMA_A1442	COG2239	Acts as a magnesium transporter
VCLMA_A1445	COG0814	amino acid
VCLMA_A1446	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCLMA_A1447	COG1131	(ABC) transporter
VCLMA_A1448	COG0842	Transport permease protein
VCLMA_A1450	COG3313	Fe-S protein
VCLMA_A1452	COG4134	Bacterial extracellular solute-binding protein
VCLMA_A1453	COG4135	transport system, permease component
VCLMA_A1454	COG4136	ATPase activity
VCLMA_A1455	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VCLMA_A1456	COG0564	pseudouridine synthase activity
VCLMA_A1457	COG0733	neurotransmitter:sodium symporter activity
VCLMA_A1460	COG0626	cystathionine gamma-synthase activity
VCLMA_A1461	COG0626	cystathionine gamma-synthase activity
VCLMA_A1462	COG2818	Glycosylase
VCLMA_A1465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCLMA_A1468	COG1842	Phage shock protein A
VCLMA_A1469	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VCLMA_A1471	COG4168	peptide transport system, permease
VCLMA_A1472	COG4171	peptide transport system, permease
VCLMA_A1474	COG4172	Belongs to the ABC transporter superfamily
VCLMA_A1477	COG1227	inorganic diphosphatase activity
VCLMA_A1481	COG3005	denitrification pathway
VCLMA_A1482	COG4459	periplasmic nitrate reductase
VCLMA_A1483	COG2116	formate transmembrane transporter activity
VCLMA_A1485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCLMA_A1486	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCLMA_A1488	COG2917	probably involved in intracellular septation
VCLMA_A1489	COG1607	acyl-coa hydrolase
VCLMA_A1490	COG2350	Protein conserved in bacteria
VCLMA_A1492	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VCLMA_A1493	COG0583	DNA-binding transcription factor activity
VCLMA_A1497	COG5001	Diguanylate cyclase
VCLMA_A1498	COG1032	radical SAM domain protein
VCLMA_A1501	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VCLMA_A1502	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VCLMA_A1503	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCLMA_A1504	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCLMA_A1505	COG0745	RESPONSE REGULATOR receiver
VCLMA_A1506	COG3381	protein complex oligomerization
VCLMA_A1508	COG3070	regulator of competence-specific genes
VCLMA_A1512	COG0297	glycogen (starch) synthase activity
VCLMA_A1518	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VCLMA_A1519	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
VCLMA_A1520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VCLMA_A1521	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCLMA_A1522	COG1960	acyl-CoA dehydrogenase activity
VCLMA_A1527	COG1012	belongs to the aldehyde dehydrogenase family
VCLMA_A1528	COG1309	transcriptional regulator
VCLMA_A1529	COG2995	paraquat-inducible protein a
VCLMA_A1530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCLMA_A1530	COG3008	intermembrane lipid transfer
VCLMA_A1534	COG0582	viral genome integration into host DNA
VCLMA_A1535	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VCLMA_A1536	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VCLMA_A1537	COG1737	Transcriptional regulator
VCLMA_A1538	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VCLMA_A1539	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCLMA_A1540	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCLMA_A1541	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCLMA_A1542	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
VCLMA_A1543	COG1940	carbohydrate kinase activity
VCLMA_A1544	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VCLMA_A1545	COG4409	exo-alpha-(2->6)-sialidase activity
VCLMA_A1547	COG2003	Belongs to the UPF0758 family
VCLMA_A1549	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VCLMA_A1552	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
VCLMA_A1553	COG1940	carbohydrate kinase activity
VCLMA_A1554	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VCLMA_A1557	COG2003	Belongs to the UPF0758 family
VCLMA_A1558	COG2003	Belongs to the UPF0758 family
VCLMA_A1568	COG0415	Belongs to the DNA photolyase family
VCLMA_A1570	COG4628	conserved protein (DUF2132)
VCLMA_A1571	COG3284	Transcriptional regulator
VCLMA_A1572	COG1012	belongs to the aldehyde dehydrogenase family
VCLMA_A1574	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCLMA_A1575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCLMA_A1576	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCLMA_A1578	COG2207	Transcriptional regulator
VCLMA_A1579	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCLMA_A1579	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCLMA_A1579	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCLMA_A1582	COG5002	protein histidine kinase activity
VCLMA_A1582	COG0784	Response regulator, receiver
VCLMA_A1584	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VCLMA_A1586	COG2885	chlorophyll binding
VCLMA_A1587	COG0823	Involved in the tonB-independent uptake of proteins
VCLMA_A1590	COG0811	peptide transport
VCLMA_A1591	COG0824	Thioesterase
VCLMA_A1592	COG1294	oxidase, subunit
VCLMA_A1593	COG1271	oxidase subunit
VCLMA_A1594	COG2255	four-way junction helicase activity
VCLMA_A1595	COG0632	four-way junction helicase activity
VCLMA_A1596	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VCLMA_A1597	COG0215	cysteine-tRNA ligase activity
VCLMA_A1598	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCLMA_A1599	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCLMA_A1600	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCLMA_A1602	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCLMA_A1603	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCLMA_A1604	COG1199	ATP-dependent helicase activity
VCLMA_A1605	COG0730	response to heat
VCLMA_A1606	COG3923	Primosomal replication protein n
VCLMA_A1608	COG0840	transmembrane signaling receptor activity
VCLMA_A1609	COG0708	Exodeoxyribonuclease III
VCLMA_A1610	COG4160	amino acid transport
VCLMA_A1611	COG4215	(ABC) transporter
VCLMA_A1617	COG0840	transmembrane signaling receptor activity
VCLMA_A1618	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VCLMA_A1620	COG3013	Belongs to the UPF0304 family
VCLMA_A1621	COG2766	serine protein kinase
VCLMA_A1624	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VCLMA_A1625	COG1663	tetraacyldisaccharide 4'-kinase activity
VCLMA_A1626	COG1132	(ABC) transporter
VCLMA_A1627	COG0658	competence protein
VCLMA_A1627	COG2333	competence protein COMEC
VCLMA_A1629	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCLMA_A1630	COG1136	(ABC) transporter
VCLMA_A1631	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCLMA_A1637	COG1252	NADH dehydrogenase
VCLMA_A1643	COG0537	adenosine 5'-monophosphoramidase activity
VCLMA_A1646	COG2186	Transcriptional regulator
VCLMA_A1648	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VCLMA_A1649	COG1674	ftsk spoiiie
VCLMA_A1652	COG0686	Belongs to the AlaDH PNT family
VCLMA_A1654	COG0583	DNA-binding transcription factor activity
VCLMA_A1658	COG0284	orotidine-5'-phosphate decarboxylase activity
VCLMA_A1659	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VCLMA_A1660	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VCLMA_A1661	COG0776	regulation of translation
VCLMA_A1662	COG0539	negative regulation of cytoplasmic translation
VCLMA_A1663	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VCLMA_A1664	COG1555	photosystem II stabilization
VCLMA_A1665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCLMA_A1666	COG0776	regulation of translation
VCLMA_A1668	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VCLMA_A1670	COG0544	peptidyl-prolyl cis-trans isomerase activity
VCLMA_A1671	COG4191	Histidine kinase
VCLMA_A1673	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCLMA_A1674	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCLMA_A1675	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCLMA_A1676	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VCLMA_A1679	COG5001	Diguanylate cyclase
VCLMA_A1679	COG3300	MHYT domain
VCLMA_A1681	COG4589	Belongs to the CDS family
VCLMA_A1687	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VCLMA_A1690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCLMA_A1693	COG0243	molybdopterin cofactor binding
VCLMA_A1694	COG3005	denitrification pathway
VCLMA_A1695	COG3325	Belongs to the glycosyl hydrolase 18 family
VCLMA_A1695	COG3469	chitinase activity
VCLMA_A1696	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCLMA_A1698	COG2951	lytic endotransglycosylase activity
VCLMA_A1699	COG3100	YcgL domain-containing protein
VCLMA_A1700	COG0850	regulation of cytokinetic process
VCLMA_A1701	COG2894	cell division
VCLMA_A1702	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VCLMA_A1703	COG3015	lipoprotein NlpE involved in copper resistance
VCLMA_A1709	COG0840	transmembrane signaling receptor activity
VCLMA_A1710	COG1396	sequence-specific DNA binding
VCLMA_A1711	COG3135	benzoate transporter
VCLMA_A1713	COG1441	menaquinone biosynthetic process
VCLMA_A1715	COG0596	Alpha beta hydrolase
VCLMA_A1716	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VCLMA_A1717	COG1169	isochorismate synthase
VCLMA_A1718	COG0436	Aminotransferase
VCLMA_A1719	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VCLMA_A1720	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VCLMA_A1723	COG0318	PFAM AMP-dependent synthetase and ligase
VCLMA_A1724	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VCLMA_A1725	COG0318	PFAM AMP-dependent synthetase and ligase
VCLMA_A1726	COG0596	Alpha beta hydrolase
VCLMA_A1729	COG1214	PFAM Peptidase M22, glycoprotease
VCLMA_A1730	COG1199	ATP-dependent helicase activity
VCLMA_A1732	COG0788	formyltetrahydrofolate deformylase activity
VCLMA_A1733	COG1902	pentaerythritol trinitrate reductase activity
VCLMA_A1733	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCLMA_A1734	COG0616	signal peptide processing
VCLMA_A1735	COG0252	asparaginase activity
VCLMA_A1736	COG3139	Protein of unknown function (DUF1315)
VCLMA_A1738	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCLMA_A1739	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCLMA_A1740	COG0676	glucose-6-phosphate 1-epimerase activity
VCLMA_A1742	COG2226	methyltransferase
VCLMA_A1745	COG0835	chemotaxis
VCLMA_A1745	COG0784	Response regulator, receiver
VCLMA_A1746	COG1940	carbohydrate kinase activity
VCLMA_A1748	COG4667	esterase of the alpha-beta hydrolase superfamily
VCLMA_A1751	COG0733	neurotransmitter:sodium symporter activity
VCLMA_A1752	COG1263	PTS System
VCLMA_A1752	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCLMA_A1753	COG0084	hydrolase, TatD family'
VCLMA_A1755	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VCLMA_A1756	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VCLMA_A1757	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCLMA_A1758	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCLMA_A1759	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VCLMA_A1760	COG1028	Short-chain dehydrogenase reductase Sdr
VCLMA_A1761	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
VCLMA_A1762	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCLMA_A1763	COG0416	fatty acid biosynthetic process
VCLMA_A1764	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VCLMA_A1765	COG1399	metal-binding, possibly nucleic acid-binding protein
VCLMA_A1766	COG0424	maF-like protein
VCLMA_A1767	COG0564	pseudouridine synthase activity
VCLMA_A1768	COG1530	ribonuclease E activity
VCLMA_A1769	COG0659	secondary active sulfate transmembrane transporter activity
VCLMA_A1771	COG1454	alcohol dehydrogenase
VCLMA_A1771	COG1012	belongs to the aldehyde dehydrogenase family
VCLMA_A1772	COG2095	MarC family integral membrane protein
VCLMA_A1773	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCLMA_A1774	COG1757	Na H antiporter
VCLMA_A1776	COG3081	Nucleoid-associated protein
VCLMA_A1778	COG3083	sulfuric ester hydrolase activity
VCLMA_A1779	COG0123	including yeast histone deacetylase and acetoin utilization protein
VCLMA_A1780	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCLMA_A1781	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VCLMA_A1786	COG2853	Lipoprotein
VCLMA_A1788	COG3088	subunit of a heme lyase
VCLMA_A1788	COG4235	cytochrome complex assembly
VCLMA_A1789	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VCLMA_A1790	COG1138	Cytochrome C-type biogenesis protein
VCLMA_A1791	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VCLMA_A1793	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCLMA_A1794	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCLMA_A1795	COG4133	protoheme IX ABC transporter activity
VCLMA_A1797	COG0835	chemotaxis
VCLMA_A1799	COG1192	Involved in chromosome partitioning
VCLMA_A1800	COG2201	protein-glutamate methylesterase activity
VCLMA_A1801	COG0643	Histidine kinase
VCLMA_A1801	COG2198	Histidine kinase
VCLMA_A1802	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VCLMA_A1805	COG0455	bacterial-type flagellum organization
VCLMA_A1808	COG2062	phosphohistidine phosphatase, SixA
VCLMA_A1809	COG1025	Belongs to the peptidase M16 family
VCLMA_A1811	COG0018	arginyl-trna synthetase
VCLMA_A1815	COG1918	ferrous iron import across plasma membrane
VCLMA_A1816	COG4977	sequence-specific DNA binding
VCLMA_A1817	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VCLMA_A1818	COG1121	(ABC) transporter
VCLMA_A1819	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VCLMA_A1821	COG0045	succinate-CoA ligase (ADP-forming) activity
VCLMA_A1822	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCLMA_A1823	COG0567	Dehydrogenase, E1 component
VCLMA_A1825	COG1053	succinate dehydrogenase
VCLMA_A1826	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VCLMA_A1827	COG2009	succinate dehydrogenase
VCLMA_A1828	COG0372	Belongs to the citrate synthase family
VCLMA_A1829	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VCLMA_A1831	COG0033	Phosphoglucomutase
VCLMA_A1832	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VCLMA_A1833	COG0596	Alpha beta hydrolase
VCLMA_A1836	COG1346	cytolysis
VCLMA_A1838	COG0583	DNA-binding transcription factor activity
VCLMA_A1840	COG0735	belongs to the Fur family
VCLMA_A1841	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCLMA_A1842	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCLMA_A1843	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCLMA_A1844	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VCLMA_A1844	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VCLMA_A1845	COG0431	NADPH-dependent FMN reductase
VCLMA_A1847	COG3101	peptidyl-lysine hydroxylation
VCLMA_A1848	COG2860	membrane
VCLMA_A1849	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VCLMA_A1850	COG2890	protein-(glutamine-N5) methyltransferase activity
VCLMA_A1852	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
VCLMA_A1853	COG1684	flagellar biosynthetic protein fliR
VCLMA_A1854	COG1987	bacterial-type flagellum assembly
VCLMA_A1859	COG1580	Controls the rotational direction of flagella during chemotaxis
VCLMA_A1864	COG1317	bacterial-type flagellum organization
VCLMA_A1865	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VCLMA_A1867	COG1677	Flagellar hook-basal body complex protein FliE
VCLMA_A1868	COG2204	response regulator
VCLMA_A1869	COG4191	Histidine kinase
VCLMA_A1870	COG2204	response regulator
VCLMA_A1871	COG1516	flagellar protein fliS
VCLMA_A1873	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VCLMA_A1874	COG1334	flagellar protein FlaG
VCLMA_A1876	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCLMA_A1877	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCLMA_A1878	COG2837	iron assimilation
VCLMA_A1882	COG1393	Belongs to the ArsC family
VCLMA_A1883	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VCLMA_A1884	COG1876	peptidase activity
VCLMA_A1886	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VCLMA_A1887	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VCLMA_A1889	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VCLMA_A1893	COG4783	chaperone-mediated protein folding
VCLMA_A1894	COG1393	Belongs to the ArsC family
VCLMA_A1898	COG2233	PERMEase
VCLMA_A1899	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VCLMA_A1901	COG0737	Belongs to the 5'-nucleotidase family
VCLMA_A1902	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VCLMA_A1903	COG2912	Transglutaminase-like superfamily
VCLMA_A1904	COG3094	Invasion gene expression up-regulator, SirB
VCLMA_A1905	COG2890	protein-(glutamine-N5) methyltransferase activity
VCLMA_A1906	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VCLMA_A1907	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VCLMA_A1908	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VCLMA_A1909	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VCLMA_A1910	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VCLMA_A1911	COG0193	aminoacyl-tRNA hydrolase activity
VCLMA_A1912	COG0012	GTP binding
VCLMA_A1913	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCLMA_A1914	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCLMA_A1917	COG1705	Flagellar rod assembly protein muramidase FlgJ
VCLMA_A1917	COG3951	Flagellar rod assembly protein muramidase FlgJ
VCLMA_A1918	COG1706	bacterial-type flagellum-dependent cell motility
VCLMA_A1919	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VCLMA_A1920	COG4786	Flagellar basal body rod
VCLMA_A1921	COG4787	bacterial-type flagellum-dependent cell motility
VCLMA_A1922	COG1749	Flagellar hook protein flgE
VCLMA_A1923	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
VCLMA_A1924	COG1558	bacterial-type flagellum-dependent cell motility
VCLMA_A1925	COG1815	bacterial-type flagellum-dependent cell motility
VCLMA_A1926	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCLMA_A1927	COG0784	Response regulator, receiver
VCLMA_A1927	COG0835	chemotaxis
VCLMA_A1934	COG2226	methyltransferase
VCLMA_A1934	COG3433	isochorismatase activity
VCLMA_A1934	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCLMA_A1935	COG2375	cellular response to nickel ion
VCLMA_A1936	COG1629	transport
VCLMA_A1936	COG4774	siderophore transport
VCLMA_A1939	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCLMA_A1940	COG2608	mercury ion transmembrane transporter activity
VCLMA_A1940	COG2217	Heavy metal translocating P-type atpase
VCLMA_A1945	COG3735	TraB family
VCLMA_A1947	COG2840	Smr protein MutS2
VCLMA_A1948	COG1187	pseudouridine synthase activity
VCLMA_A1949	COG3706	GGDEF domain
VCLMA_A1950	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VCLMA_A1951	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VCLMA_A1952	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VCLMA_A1953	COG0121	glutamine amidotransferase
VCLMA_A1954	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCLMA_A1955	COG1960	acyl-CoA dehydrogenase activity
VCLMA_A1957	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VCLMA_A1958	COG0328	RNA-DNA hybrid ribonuclease activity
VCLMA_A1959	COG2226	methyltransferase
VCLMA_A1960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCLMA_A1961	COG0741	lytic transglycosylase activity
VCLMA_A1961	COG1388	LysM domain
VCLMA_A1963	COG0347	Belongs to the P(II) protein family
VCLMA_A1964	COG3479	Phenolic acid decarboxylase
VCLMA_A1966	COG0037	tRNA processing
VCLMA_A1967	COG0825	malonyl-CoA metabolic process
VCLMA_A1968	COG0587	DNA-directed DNA polymerase activity
VCLMA_A1970	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCLMA_A1971	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCLMA_A1972	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCLMA_A1973	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCLMA_A1974	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VCLMA_A1976	COG0750	zinc metalloprotease
VCLMA_A1977	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VCLMA_A1978	COG0575	Belongs to the CDS family
VCLMA_A1979	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VCLMA_A1980	COG0233	cytoplasmic translational termination
VCLMA_A1981	COG0528	UMP kinase activity
VCLMA_A1982	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VCLMA_A1983	COG0052	Belongs to the universal ribosomal protein uS2 family
VCLMA_A1984	COG0024	Methionine aminopeptidase
VCLMA_A1985	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VCLMA_A1987	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VCLMA_A1988	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VCLMA_A1989	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCLMA_A1990	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VCLMA_A1993	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCLMA_A1993	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCLMA_A1994	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VCLMA_A1995	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VCLMA_A1996	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VCLMA_A1999	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VCLMA_A2000	COG2252	PERMEase
VCLMA_A2001	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCLMA_A2002	COG0189	ligase activity
VCLMA_A2002	COG4067	protein conserved in archaea
VCLMA_A2003	COG0189	ligase activity
VCLMA_A2005	COG0733	neurotransmitter:sodium symporter activity
VCLMA_A2006	COG3706	GGDEF domain
VCLMA_A2008	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VCLMA_A2010	COG1477	protein flavinylation
VCLMA_A2011	COG2871	sodium ion transport
VCLMA_A2012	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCLMA_A2013	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCLMA_A2014	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCLMA_A2015	COG1805	sodium ion transport
VCLMA_A2016	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCLMA_A2017	COG0271	Belongs to the BolA IbaG family
VCLMA_A2018	COG2813	Specifically methylates the guanine in position
VCLMA_A2021	COG2211	Major facilitator Superfamily
VCLMA_A2025	COG3248	Nucleoside-binding outer membrane protein
VCLMA_A2026	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VCLMA_A2028	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCLMA_A2029	COG2166	iron-sulfur cluster assembly
VCLMA_A2030	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VCLMA_A2031	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VCLMA_A2033	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VCLMA_A2033	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCLMA_A2035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VCLMA_A2036	COG1074	ATP-dependent DNA helicase activity
VCLMA_A2037	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VCLMA_A2040	COG3141	response to X-ray
VCLMA_A2041	COG2171	N-acyltransferase activity
VCLMA_A2043	COG0456	acetyltransferase
VCLMA_A2044	COG0189	ligase activity
VCLMA_A2044	COG0569	domain protein
VCLMA_A2047	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCLMA_A2048	COG1609	Transcriptional regulator
VCLMA_A2049	COG3250	beta-galactosidase activity
VCLMA_A2052	COG1022	Amp-dependent synthetase and ligase
VCLMA_A2053	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCLMA_A2054	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VCLMA_A2056	COG0560	Phosphoserine phosphatase
VCLMA_A2058	COG0813	purine-nucleoside phosphorylase activity
VCLMA_A2059	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VCLMA_A2060	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VCLMA_A2061	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VCLMA_A2063	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCLMA_A2064	COG0084	hydrolase, TatD family'
VCLMA_A2067	COG1115	amino acid carrier protein
VCLMA_A2070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VCLMA_A2071	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VCLMA_A2072	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VCLMA_A2074	COG0083	homoserine kinase activity
VCLMA_A2077	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCLMA_A2079	COG0745	RESPONSE REGULATOR receiver
VCLMA_A2080	COG5002	protein histidine kinase activity
VCLMA_A2080	COG2198	Histidine kinase
VCLMA_A2080	COG0784	Response regulator, receiver
VCLMA_A2081	COG2203	Gaf domain
VCLMA_A2081	COG5001	Diguanylate cyclase
VCLMA_A2081	COG4251	negative regulation of phosphorylation
VCLMA_A2081	COG3706	GGDEF domain
VCLMA_A2082	COG1242	4 iron, 4 sulfur cluster binding
VCLMA_A2083	COG0070	glutamate synthase
VCLMA_A2083	COG0069	glutamate synthase activity
VCLMA_A2083	COG0067	glutamate synthase
VCLMA_A2085	COG0069	glutamate synthase activity
VCLMA_A2085	COG0070	glutamate synthase
VCLMA_A2085	COG0067	glutamate synthase
VCLMA_A2086	COG0493	'glutamate synthase
VCLMA_A2088	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VCLMA_A2090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VCLMA_A2091	COG2860	membrane
VCLMA_A2092	COG0583	DNA-binding transcription factor activity
VCLMA_A2093	COG0730	response to heat
VCLMA_A2095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VCLMA_A2096	COG0505	Belongs to the CarA family
VCLMA_A2098	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
VCLMA_A2099	COG0494	nUDIX hydrolase
VCLMA_A2100	COG0653	protein targeting
VCLMA_A2102	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VCLMA_A2103	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VCLMA_A2104	COG0849	cell division
VCLMA_A2105	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VCLMA_A2106	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCLMA_A2107	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
VCLMA_A2108	COG0772	Belongs to the SEDS family
VCLMA_A2109	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VCLMA_A2110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VCLMA_A2111	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VCLMA_A2112	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VCLMA_A2113	COG0768	penicillin binding
VCLMA_A2114	COG3116	cell division
VCLMA_A2115	COG0275	rRNA processing
VCLMA_A2116	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCLMA_A2118	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VCLMA_A2119	COG2186	Transcriptional regulator
VCLMA_A2120	COG0737	Belongs to the 5'-nucleotidase family
VCLMA_A2121	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VCLMA_A2122	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCLMA_A2123	COG4974	Belongs to the 'phage' integrase family
VCLMA_A2124	COG0716	FMN binding
VCLMA_A2127	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCLMA_A2128	COG1459	type II secretion system
VCLMA_A2130	COG0237	dephospho-CoA kinase activity
VCLMA_A2131	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VCLMA_A2132	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
VCLMA_A2133	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VCLMA_A2134	COG0187	DNA topoisomerase II activity
VCLMA_A2135	COG3150	esterase
VCLMA_A2137	COG3151	Protein conserved in bacteria
VCLMA_A2138	COG0494	nUDIX hydrolase
VCLMA_A2139	COG1538	Outer membrane efflux protein
VCLMA_A2141	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VCLMA_A2142	COG0840	transmembrane signaling receptor activity
VCLMA_A2145	COG1392	Phosphate transport regulator
VCLMA_A2146	COG0306	phosphate transporter
VCLMA_A2147	COG4991	sh3 domain protein
VCLMA_A2149	COG3267	Type II secretory pathway component ExeA
VCLMA_A2149	COG3409	Peptidoglycan-binding domain 1 protein
VCLMA_A2150	COG0617	tRNA 3'-terminal CCA addition
VCLMA_A2151	COG0148	phosphopyruvate hydratase activity
VCLMA_A2152	COG0504	CTP synthase activity
VCLMA_A2154	COG3956	TIGRFAM MazG family protein
VCLMA_A2155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCLMA_A2156	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCLMA_A2158	COG5001	Diguanylate cyclase
VCLMA_A2161	COG0736	holo-[acyl-carrier-protein] synthase activity
VCLMA_A2162	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VCLMA_A2163	COG1381	Involved in DNA repair and RecF pathway recombination
VCLMA_A2164	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VCLMA_A2165	COG0571	ribonuclease III activity
VCLMA_A2166	COG0681	Belongs to the peptidase S26 family
VCLMA_A2167	COG0481	GTPase activity
VCLMA_A2168	COG3086	response to oxidative stress
VCLMA_A2169	COG3026	antisigma factor binding
VCLMA_A2171	COG1595	DNA-templated transcription, initiation
VCLMA_A2172	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VCLMA_A2174	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VCLMA_A2175	COG0354	folic acid binding
VCLMA_A2177	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCLMA_A2178	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCLMA_A2180	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VCLMA_A2181	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VCLMA_A2182	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VCLMA_A2183	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCLMA_A2184	COG0440	acetolactate synthase activity
VCLMA_A2185	COG0028	Belongs to the TPP enzyme family
VCLMA_A2186	COG1022	Amp-dependent synthetase and ligase
VCLMA_A2187	COG0583	DNA-binding transcription factor activity
VCLMA_A2191	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VCLMA_A2192	COG0473	3-isopropylmalate dehydrogenase activity
VCLMA_A2193	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
VCLMA_A2194	COG0066	3-isopropylmalate dehydratase activity
VCLMA_A2197	COG3437	response regulator, receiver
VCLMA_A2199	COG0795	lipopolysaccharide-transporting ATPase activity
VCLMA_A2200	COG0795	lipopolysaccharide-transporting ATPase activity
VCLMA_A2201	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCLMA_A2202	COG2927	DNA polymerase III (CHI subunit)
VCLMA_A2203	COG0525	valine-tRNA ligase activity
VCLMA_A2204	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCLMA_A2205	COG0564	pseudouridine synthase activity
VCLMA_A2206	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VCLMA_A2209	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
VCLMA_A2210	COG0540	Belongs to the ATCase OTCase family
VCLMA_A2211	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
VCLMA_A2212	COG0251	oxidation-reduction process
VCLMA_A2213	COG0204	Acyl-transferase
VCLMA_A2214	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VCLMA_A2215	COG5007	Belongs to the BolA IbaG family
VCLMA_A2217	COG2854	intermembrane phospholipid transfer
VCLMA_A2218	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCLMA_A2219	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VCLMA_A2220	COG1127	ABC transporter
VCLMA_A2222	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VCLMA_A2222	COG0517	IMP dehydrogenase activity
VCLMA_A2225	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VCLMA_A2226	COG1137	ATPase activity
VCLMA_A2228	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCLMA_A2229	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCLMA_A2231	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCLMA_A2232	COG2239	Acts as a magnesium transporter
VCLMA_A2233	COG0312	modulator of DNA gyrase
VCLMA_A2234	COG3028	Belongs to the UPF0307 family
VCLMA_A2235	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VCLMA_A2236	COG1178	ABC-type Fe3 transport system permease component
VCLMA_A2237	COG4143	(ABC) transporter
VCLMA_A2239	COG0163	prenyltransferase activity
VCLMA_A2240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCLMA_A2241	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
VCLMA_A2242	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VCLMA_A2243	COG2105	PFAM AIG2 family protein
VCLMA_A2245	COG0729	surface antigen
VCLMA_A2246	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCLMA_A2247	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VCLMA_A2250	COG1136	(ABC) transporter
VCLMA_A2254	COG0529	Catalyzes the synthesis of activated sulfate
VCLMA_A2255	COG2895	sulfate adenylyltransferase (ATP) activity
VCLMA_A2256	COG0175	sulfate reduction
VCLMA_A2257	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VCLMA_A2257	COG1648	precorrin-2 dehydrogenase activity
VCLMA_A2258	COG0737	Belongs to the 5'-nucleotidase family
VCLMA_A2260	COG0513	Belongs to the DEAD box helicase family
VCLMA_A2261	COG2153	protein acetylation
VCLMA_A2262	COG0697	spore germination
VCLMA_A2264	COG0545	Peptidyl-prolyl cis-trans isomerase
VCLMA_A2266	COG0203	ribosomal protein L17
VCLMA_A2267	COG0202	RNA polymerase activity
VCLMA_A2268	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VCLMA_A2269	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VCLMA_A2270	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VCLMA_A2272	COG0201	protein transport
VCLMA_A2273	COG0200	Binds to the 23S rRNA
VCLMA_A2274	COG1841	ribosomal large subunit assembly
VCLMA_A2275	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VCLMA_A2276	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VCLMA_A2277	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
VCLMA_A2278	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VCLMA_A2279	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VCLMA_A2280	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VCLMA_A2281	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VCLMA_A2282	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VCLMA_A2283	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VCLMA_A2284	COG0255	Belongs to the universal ribosomal protein uL29 family
VCLMA_A2285	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VCLMA_A2286	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VCLMA_A2287	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VCLMA_A2288	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VCLMA_A2289	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VCLMA_A2290	COG0089	rRNA binding
VCLMA_A2291	COG0088	Forms part of the polypeptide exit tunnel
VCLMA_A2292	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VCLMA_A2293	COG0051	transcription antitermination factor activity, RNA binding
VCLMA_A2294	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCLMA_A2295	COG0557	exoribonuclease II activity
VCLMA_A2296	COG3083	sulfuric ester hydrolase activity
VCLMA_A2297	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VCLMA_A2298	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VCLMA_A2300	COG1047	Peptidyl-prolyl cis-trans
VCLMA_A2303	COG2249	NAD(P)H dehydrogenase (quinone) activity
VCLMA_A2304	COG0488	(ABC) transporter
VCLMA_A2306	COG0429	hydrolase of the alpha beta-hydrolase fold
VCLMA_A2308	COG3954	Phosphoribulokinase
VCLMA_A2309	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VCLMA_A2313	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VCLMA_A2315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCLMA_A2318	COG0180	Tryptophanyl-tRNA synthetase
VCLMA_A2319	COG0546	phosphoglycolate phosphatase activity
VCLMA_A2320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VCLMA_A2321	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VCLMA_A2323	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VCLMA_A2324	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VCLMA_A2332	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCLMA_A2332	COG0678	peroxiredoxin activity
VCLMA_A2333	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCLMA_A2335	COG0165	Argininosuccinate lyase
VCLMA_A2336	COG0137	argininosuccinate synthase activity
VCLMA_A2337	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCLMA_A2338	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VCLMA_A2339	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VCLMA_A2340	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VCLMA_A2343	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VCLMA_A2344	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VCLMA_A2345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCLMA_A2346	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VCLMA_A2347	COG1053	succinate dehydrogenase
VCLMA_A2348	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VCLMA_A2349	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VCLMA_A2350	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VCLMA_A2351	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCLMA_A2352	COG1509	lysine 2,3-aminomutase activity
VCLMA_A2354	COG0459	protein refolding
VCLMA_A2355	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCLMA_A2360	COG0149	triose-phosphate isomerase activity
VCLMA_A2362	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCLMA_A2363	COG1575	Belongs to the MenA family. Type 1 subfamily
VCLMA_A2364	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VCLMA_A2365	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VCLMA_A2366	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCLMA_A2368	COG1609	Transcriptional regulator
VCLMA_A2369	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VCLMA_A2370	COG0254	rRNA binding
VCLMA_A2373	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
VCLMA_A2374	COG0626	cystathionine gamma-synthase activity
VCLMA_A2375	COG0460	homoserine dehydrogenase
VCLMA_A2375	COG0527	aspartate kinase activity
VCLMA_A2376	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VCLMA_A2377	COG3074	FtsZ-dependent cytokinesis
VCLMA_A2378	COG1494	fructose-1,6-bisphosphatase
VCLMA_A2379	COG0205	6-phosphofructokinase activity
VCLMA_A2380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VCLMA_A2382	COG0745	RESPONSE REGULATOR receiver
VCLMA_A2383	COG2205	protein histidine kinase activity
VCLMA_A2385	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VCLMA_A2386	COG3030	protein affecting phage T7 exclusion by the F plasmid
VCLMA_A2387	COG3706	GGDEF domain
VCLMA_A2388	COG1027	Aspartate ammonia-lyase
VCLMA_A2389	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCLMA_A2391	COG4232	protein-disulfide reductase activity
VCLMA_A2393	COG3263	regulation of cellular component size
VCLMA_A2396	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VCLMA_A2398	COG0194	GDP metabolic process
VCLMA_A2399	COG1758	RNA polymerase activity
VCLMA_A2400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCLMA_A2401	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VCLMA_A2402	COG2233	PERMEase
VCLMA_A2404	COG0745	RESPONSE REGULATOR receiver
VCLMA_A2405	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCLMA_A2406	COG2183	response to ionizing radiation
VCLMA_A2408	COG0596	Alpha beta hydrolase
VCLMA_A2410	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
VCLMA_A2410	COG0316	Belongs to the HesB IscA family
VCLMA_A2411	COG0494	nUDIX hydrolase
VCLMA_A2412	COG1218	3'(2'),5'-bisphosphate nucleotidase
VCLMA_A2414	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCLMA_A2415	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCLMA_A2416	COG3156	type II secretion system protein K
VCLMA_A2417	COG4795	General secretion pathway protein
VCLMA_A2418	COG2165	general secretion pathway protein
VCLMA_A2419	COG2165	general secretion pathway protein
VCLMA_A2420	COG2165	general secretion pathway protein
VCLMA_A2421	COG1459	type II secretion system
VCLMA_A2424	COG3031	protein transport across the cell outer membrane
VCLMA_A2425	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VCLMA_A2426	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VCLMA_A2427	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
VCLMA_A2429	COG0456	acetyltransferase
VCLMA_A2430	COG1490	D-aminoacyl-tRNA deacylase activity
VCLMA_A2436	COG0174	glutamine synthetase
VCLMA_A2438	COG3852	Histidine kinase
VCLMA_A2440	COG3300	MHYT domain
VCLMA_A2440	COG5001	Diguanylate cyclase
VCLMA_A2441	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VCLMA_A2445	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
VCLMA_A2446	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCLMA_A2447	COG1739	Uncharacterized protein family UPF0029
VCLMA_A2448	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCLMA_A2448	COG1024	Enoyl-CoA hydratase
VCLMA_A2449	COG0183	Belongs to the thiolase family
VCLMA_A2450	COG0583	DNA-binding transcription factor activity
VCLMA_A2451	COG2814	Major facilitator Superfamily
VCLMA_A2453	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VCLMA_A2454	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VCLMA_A2455	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VCLMA_A2456	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VCLMA_A2457	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VCLMA_A2458	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VCLMA_A2460	COG0356	it plays a direct role in the translocation of protons across the membrane
VCLMA_A2461	COG3312	ion transport
VCLMA_A2462	COG1475	DNA binding
VCLMA_A2463	COG1192	Involved in chromosome partitioning
VCLMA_A2464	COG0357	Ribosomal RNA small subunit methyltransferase G
VCLMA_A2465	COG0445	tRNA wobble uridine modification
VCLMA_B0006	COG0217	transcriptional regulatory protein
VCLMA_B0007	COG2084	Dehydrogenase
VCLMA_B0011	COG0058	SHG alpha-glucan phosphorylase activity
VCLMA_B0012	COG1640	4-alpha-glucanotransferase
VCLMA_B0013	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VCLMA_B0015	COG3501	Rhs element vgr protein
VCLMA_B0022	COG0471	metal ion transport
VCLMA_B0023	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCLMA_B0031	COG0671	phosphoesterase, PA-phosphatase related
VCLMA_B0032	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VCLMA_B0034	COG1999	signal sequence binding
VCLMA_B0037	COG0786	glutamate:sodium symporter activity
VCLMA_B0041	COG1566	PFAM secretion protein HlyD family protein
VCLMA_B0043	COG3706	GGDEF domain
VCLMA_B0046	COG0813	purine-nucleoside phosphorylase activity
VCLMA_B0047	COG3272	Protein of unknown function (DUF1722)
VCLMA_B0049	COG0415	Belongs to the DNA photolyase family
VCLMA_B0050	COG1388	LysM domain
VCLMA_B0050	COG1376	ErfK ybiS ycfS ynhG family protein
VCLMA_B0053	COG0513	Belongs to the DEAD box helicase family
VCLMA_B0060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCLMA_B0061	COG0573	inorganic phosphate transmembrane transporter activity
VCLMA_B0062	COG0581	inorganic phosphate transmembrane transporter activity
VCLMA_B0063	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCLMA_B0068	COG0659	secondary active sulfate transmembrane transporter activity
VCLMA_B0070	COG0739	heme binding
VCLMA_B0071	COG3300	MHYT domain
VCLMA_B0071	COG5001	Diguanylate cyclase
VCLMA_B0072	COG0583	DNA-binding transcription factor activity
VCLMA_B0073	COG2814	Major facilitator Superfamily
VCLMA_B0078	COG1301	dicarboxylic acid transport
VCLMA_B0080	COG1342	Belongs to the UPF0251 family
VCLMA_B0086	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VCLMA_B0087	COG0673	inositol 2-dehydrogenase activity
VCLMA_B0090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCLMA_B0092	COG0564	pseudouridine synthase activity
VCLMA_B0110	COG3501	Rhs element vgr protein
VCLMA_B0112	COG1869	D-ribose catabolic process
VCLMA_B0113	COG1129	ABC transporter
VCLMA_B0114	COG1172	Belongs to the binding-protein-dependent transport system permease family
VCLMA_B0115	COG1879	ABC-type sugar transport system periplasmic component
VCLMA_B0116	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCLMA_B0117	COG1609	Transcriptional regulator
VCLMA_B0119	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCLMA_B0121	COG0584	glycerophosphoryl diester phosphodiesterase
VCLMA_B0122	COG2271	Major facilitator Superfamily
VCLMA_B0130	COG0579	oxidoreductase
VCLMA_B0132	COG0242	peptide deformylase activity
VCLMA_B0133	COG1017	nitric oxide dioxygenase activity
VCLMA_B0133	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCLMA_B0134	COG1320	monovalent cation:proton antiporter activity
VCLMA_B0135	COG2212	antiporter activity
VCLMA_B0139	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCLMA_B0139	COG2111	Na H antiporter
VCLMA_B0141	COG0589	response to stress
VCLMA_B0142	COG0814	amino acid
VCLMA_B0143	COG3033	Beta-eliminating lyase
VCLMA_B0146	COG3530	Putative quorum-sensing-regulated virulence factor
VCLMA_B0148	COG5002	protein histidine kinase activity
VCLMA_B0148	COG5001	Diguanylate cyclase
VCLMA_B0149	COG1278	Cold shock
VCLMA_B0152	COG2304	oxidoreductase activity
VCLMA_B0156	COG0714	Associated with various cellular activities
VCLMA_B0157	COG0840	transmembrane signaling receptor activity
VCLMA_B0160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCLMA_B0162	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCLMA_B0164	COG3604	Transcriptional regulator
VCLMA_B0165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCLMA_B0165	COG1017	nitric oxide dioxygenase activity
VCLMA_B0166	COG1278	Cold shock
VCLMA_B0167	COG3036	rescue of stalled ribosome
VCLMA_B0173	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VCLMA_B0173	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VCLMA_B0174	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCLMA_B0176	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCLMA_B0178	COG0516	GMP reductase activity
VCLMA_B0179	COG0513	Belongs to the DEAD box helicase family
VCLMA_B0180	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCLMA_B0182	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VCLMA_B0183	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VCLMA_B0184	COG0784	Response regulator, receiver
VCLMA_B0184	COG3437	response regulator, receiver
VCLMA_B0185	COG4191	Histidine kinase
VCLMA_B0185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCLMA_B0187	COG1757	Na H antiporter
VCLMA_B0188	COG2814	Major facilitator Superfamily
VCLMA_B0190	COG3706	GGDEF domain
VCLMA_B0191	COG3240	lipase activity
VCLMA_B0194	COG0840	transmembrane signaling receptor activity
VCLMA_B0195	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VCLMA_B0196	COG5380	lipid catabolic process
VCLMA_B0197	COG4412	M6 family metalloprotease domain protein
VCLMA_B0197	COG3291	Pkd domain containing protein
VCLMA_B0201	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCLMA_B0202	COG4605	iron ion homeostasis
VCLMA_B0203	COG4604	ABC transporter, ATP-binding protein
VCLMA_B0207	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCLMA_B0211	COG0745	RESPONSE REGULATOR receiver
VCLMA_B0213	COG3623	hexulose-6-phosphate isomerase
VCLMA_B0214	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
VCLMA_B0215	COG0561	phosphatase activity
VCLMA_B0222	COG0366	Alpha amylase catalytic
VCLMA_B0226	COG0745	RESPONSE REGULATOR receiver
VCLMA_B0227	COG5002	protein histidine kinase activity
VCLMA_B0235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCLMA_B0239	COG1686	Belongs to the peptidase S11 family
VCLMA_B0242	COG3338	carbonate dehydratase activity
VCLMA_B0246	COG0509	glycine decarboxylation via glycine cleavage system
VCLMA_B0247	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCLMA_B0250	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
VCLMA_B0252	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VCLMA_B0253	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
VCLMA_B0255	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
VCLMA_B0257	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VCLMA_B0258	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
VCLMA_B0265	COG0494	nUDIX hydrolase
VCLMA_B0283	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
VCLMA_B0286	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
VCLMA_B0287	COG2944	sequence-specific DNA binding
VCLMA_B0289	COG0110	maltose O-acetyltransferase activity
VCLMA_B0297	COG1943	Transposase
VCLMA_B0308	COG0346	lactoylglutathione lyase activity
VCLMA_B0311	COG0602	queuosine metabolic process
VCLMA_B0313	COG0189	ligase activity
VCLMA_B0313	COG4067	protein conserved in archaea
VCLMA_B0314	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCLMA_B0314	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VCLMA_B0314	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCLMA_B0315	COG1105	Belongs to the carbohydrate kinase PfkB family
VCLMA_B0316	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCLMA_B0316	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCLMA_B0317	COG1609	Transcriptional regulator
VCLMA_B0318	COG0420	3'-5' exonuclease activity
VCLMA_B0319	COG0419	ATPase involved in DNA repair
VCLMA_B0320	COG0784	Response regulator, receiver
VCLMA_B0320	COG2205	protein histidine kinase activity
VCLMA_B0321	COG0156	8-amino-7-oxononanoate synthase activity
VCLMA_B0323	COG0038	chloride channel
VCLMA_B0324	COG0523	cobalamin synthesis protein
VCLMA_B0326	COG3158	transport of potassium into the cell
VCLMA_B0327	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
VCLMA_B0327	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VCLMA_B0327	COG1013	pyruvate-flavodoxin oxidoreductase activity
VCLMA_B0327	COG0674	pyruvate-flavodoxin oxidoreductase activity
VCLMA_B0328	COG2205	protein histidine kinase activity
VCLMA_B0329	COG0745	RESPONSE REGULATOR receiver
VCLMA_B0330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCLMA_B0333	COG2200	EAL domain
VCLMA_B0335	COG3038	cytochrome b561
VCLMA_B0337	COG2116	formate transmembrane transporter activity
VCLMA_B0338	COG0583	DNA-binding transcription factor activity
VCLMA_B0340	COG3593	DNA synthesis involved in DNA repair
VCLMA_B0341	COG0737	Belongs to the 5'-nucleotidase family
VCLMA_B0345	COG2824	Alkylphosphonate utilization operon protein PhnA
VCLMA_B0357	COG3706	GGDEF domain
VCLMA_B0360	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VCLMA_B0361	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VCLMA_B0363	COG0745	RESPONSE REGULATOR receiver
VCLMA_B0367	COG0023	Translation Initiation Factor
VCLMA_B0369	COG1181	Belongs to the D-alanine--D-alanine ligase family
VCLMA_B0371	COG0045	succinate-CoA ligase (ADP-forming) activity
VCLMA_B0371	COG1042	CoA-binding domain protein
VCLMA_B0371	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCLMA_B0372	COG0583	DNA-binding transcription factor activity
VCLMA_B0373	COG4771	TonB-dependent receptor
VCLMA_B0373	COG1629	transport
VCLMA_B0376	COG2050	protein possibly involved in aromatic compounds catabolism
VCLMA_B0380	COG0625	glutathione transferase activity
VCLMA_B0383	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VCLMA_B0384	COG4172	Belongs to the ABC transporter superfamily
VCLMA_B0385	COG4239	(ABC) transporter, permease
VCLMA_B0386	COG4174	ABC transporter (Permease)
VCLMA_B0387	COG4166	transmembrane transport
VCLMA_B0396	COG3842	ATPase activity
VCLMA_B0398	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCLMA_B0400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCLMA_B0401	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCLMA_B0402	COG1011	Hydrolase
VCLMA_B0404	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VCLMA_B0405	COG1970	mechanosensitive ion channel activity
VCLMA_B0407	COG2759	Belongs to the formate--tetrahydrofolate ligase family
VCLMA_B0408	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCLMA_B0408	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCLMA_B0409	COG0302	gtp cyclohydrolase
VCLMA_B0411	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCLMA_B0413	COG2897	thiosulfate sulfurtransferase activity
VCLMA_B0415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
VCLMA_B0420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCLMA_B0425	COG0583	DNA-binding transcription factor activity
VCLMA_B0426	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
VCLMA_B0427	COG0778	Nitroreductase
VCLMA_B0432	COG0640	Transcriptional regulator
VCLMA_B0434	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCLMA_B0443	COG1263	PTS System
VCLMA_B0443	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCLMA_B0445	COG1621	beta-fructofuranosidase activity
VCLMA_B0446	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCLMA_B0447	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCLMA_B0450	COG0545	Peptidyl-prolyl cis-trans isomerase
VCLMA_B0451	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCLMA_B0452	COG0840	transmembrane signaling receptor activity
VCLMA_B0453	COG3069	C4-dicarboxylate transmembrane transporter activity
VCLMA_B0454	COG1760	l-serine dehydratase
VCLMA_B0459	COG1609	Transcriptional regulator
VCLMA_B0460	COG2197	response regulator
VCLMA_B0461	COG3850	Histidine kinase
VCLMA_B0462	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCLMA_B0464	COG0243	molybdopterin cofactor binding
VCLMA_B0468	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCLMA_B0469	COG2197	response regulator
VCLMA_B0471	COG2271	Major facilitator Superfamily
VCLMA_B0472	COG1840	ABC-type Fe3 transport system, periplasmic component
VCLMA_B0474	COG3842	ATPase activity
VCLMA_B0475	COG3243	poly(R)-hydroxyalkanoic acid synthase
VCLMA_B0477	COG0183	Belongs to the thiolase family
VCLMA_B0479	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCLMA_B0480	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCLMA_B0483	COG3706	GGDEF domain
VCLMA_B0484	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCLMA_B0486	COG1979	alcohol dehydrogenase
VCLMA_B0489	COG4191	Histidine kinase
VCLMA_B0490	COG1840	ABC-type Fe3 transport system, periplasmic component
VCLMA_B0492	COG2271	Major facilitator Superfamily
VCLMA_B0493	COG0469	pyruvate kinase activity
VCLMA_B0495	COG1879	ABC-type sugar transport system periplasmic component
VCLMA_B0496	COG1803	Methylglyoxal synthase
VCLMA_B0497	COG1335	isochorismatase
VCLMA_B0499	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VCLMA_B0502	COG0210	DNA helicase
VCLMA_B0503	COG1289	transmembrane transporter activity
VCLMA_B0509	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
VCLMA_B0510	COG4149	molybdate abc transporter
VCLMA_B0511	COG0725	ABC transporter, periplasmic molybdate-binding protein
VCLMA_B0512	COG1492	cobalamin metabolic process
VCLMA_B0519	COG5002	protein histidine kinase activity
VCLMA_B0519	COG0784	Response regulator, receiver
VCLMA_B0520	COG1879	ABC-type sugar transport system periplasmic component
VCLMA_B0522	COG2827	Endonuclease containing a URI domain
VCLMA_B0529	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VCLMA_B0530	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCLMA_B0531	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
VCLMA_B0532	COG0247	lactate metabolic process
VCLMA_B0533	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCLMA_B0534	COG3118	belongs to the thioredoxin family
VCLMA_B0538	COG0583	DNA-binding transcription factor activity
VCLMA_B0539	COG4160	amino acid transport
VCLMA_B0540	COG4215	(ABC) transporter
VCLMA_B0541	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCLMA_B0542	COG1126	abc transporter atp-binding protein
VCLMA_B0544	COG2425	protein containing a von Willebrand factor type A (vWA) domain
VCLMA_B0546	COG0494	nUDIX hydrolase
VCLMA_B0547	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VCLMA_B0549	COG1309	transcriptional regulator
VCLMA_B0550	COG0513	Belongs to the DEAD box helicase family
VCLMA_B0551	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
VCLMA_B0553	COG0814	amino acid
VCLMA_B0554	COG0840	transmembrane signaling receptor activity
VCLMA_B0555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VCLMA_B0557	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
VCLMA_B0559	COG1984	allophanate hydrolase subunit 2
VCLMA_B0563	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VCLMA_B0564	COG4181	ATPase activity
VCLMA_B0566	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCLMA_B0569	COG0484	heat shock protein binding
VCLMA_B0576	COG0546	phosphoglycolate phosphatase activity
VCLMA_B0579	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCLMA_B0580	COG1368	sulfuric ester hydrolase activity
VCLMA_B0582	COG0513	Belongs to the DEAD box helicase family
VCLMA_B0583	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
VCLMA_B0585	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCLMA_B0588	COG3397	chitin binding
VCLMA_B0589	COG3227	Zinc metalloprotease (Elastase)
VCLMA_B0591	COG0010	Belongs to the arginase family
VCLMA_B0592	COG1166	arginine decarboxylase activity
VCLMA_B0595	COG2239	Acts as a magnesium transporter
VCLMA_B0596	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCLMA_B0597	COG0459	protein refolding
VCLMA_B0599	COG0527	aspartate kinase activity
VCLMA_B0600	COG0662	Cupin 2, conserved barrel domain protein
VCLMA_B0601	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VCLMA_B0602	COG0456	acetyltransferase
VCLMA_B0603	COG2154	pterin-4-alpha-carbinolamine dehydratase
VCLMA_B0604	COG3186	Phenylalanine-4-hydroxylase
VCLMA_B0605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCLMA_B0608	COG2264	protein methyltransferase activity
VCLMA_B0609	COG0583	DNA-binding transcription factor activity
VCLMA_B0612	COG2171	N-acyltransferase activity
VCLMA_B0613	COG1253	flavin adenine dinucleotide binding
VCLMA_B0615	COG1765	OsmC-like protein
VCLMA_B0621	COG0531	amino acid
VCLMA_B0622	COG3706	GGDEF domain
VCLMA_B0624	COG3279	Response regulator of the LytR AlgR family
VCLMA_B0625	COG3275	phosphorelay sensor kinase activity
VCLMA_B0628	COG1136	(ABC) transporter
VCLMA_B0628	COG0577	efflux transmembrane transporter activity
VCLMA_B0629	COG1136	(ABC) transporter
VCLMA_B0632	COG4989	oxidoreductase activity
VCLMA_B0633	COG0366	Alpha amylase catalytic
VCLMA_B0635	COG2067	long-chain fatty acid transport protein
VCLMA_B0638	COG3227	Zinc metalloprotease (Elastase)
VCLMA_B0641	COG1686	Belongs to the peptidase S11 family
VCLMA_B0642	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VCLMA_B0643	COG1271	oxidase subunit
VCLMA_B0644	COG1294	oxidase, subunit
VCLMA_B0646	COG3048	D-serine ammonia-lyase activity
VCLMA_B0647	COG0583	DNA-binding transcription factor activity
VCLMA_B0648	COG1063	alcohol dehydrogenase
VCLMA_B0649	COG0156	8-amino-7-oxononanoate synthase activity
VCLMA_B0650	COG0693	protein deglycase activity
VCLMA_B0653	COG0346	lactoylglutathione lyase activity
VCLMA_B0657	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
VCLMA_B0659	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VCLMA_B0660	COG0363	glucosamine-6-phosphate deaminase activity
VCLMA_B0661	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VCLMA_B0666	COG1929	Belongs to the glycerate kinase type-1 family
VCLMA_B0667	COG2610	gluconate transmembrane transporter activity
VCLMA_B0668	COG3835	regulator
VCLMA_B0670	COG0748	coenzyme F420 binding
VCLMA_B0671	COG3721	Heme iron utilization protein
VCLMA_B0673	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCLMA_B0674	COG0811	peptide transport
VCLMA_B0675	COG0848	biopolymer transport protein
VCLMA_B0676	COG4558	Periplasmic binding protein
VCLMA_B0677	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCLMA_B0678	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VCLMA_B0685	COG0633	Ferredoxin
VCLMA_B0685	COG3217	Mosc domain protein beta barrel domain protein
VCLMA_B0685	COG0633	Ferredoxin
VCLMA_B0685	COG3217	Mosc domain protein beta barrel domain protein
VCLMA_B0686	COG0418	dihydroorotase activity
VCLMA_B0688	COG3152	Membrane
VCLMA_B0690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCLMA_B0691	COG2354	Protein conserved in bacteria
VCLMA_B0692	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCLMA_B0693	COG1278	Cold shock
VCLMA_B0698	COG3706	GGDEF domain
VCLMA_B0699	COG1349	DNA-binding transcription factor activity
VCLMA_B0702	COG3833	ABC-type maltose transport systems, permease component
VCLMA_B0703	COG1175	transmembrane transport
VCLMA_B0705	COG3842	ATPase activity
VCLMA_B0706	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCLMA_B0709	COG0393	Putative heavy-metal-binding
VCLMA_B0710	COG2197	response regulator
VCLMA_B0711	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCLMA_B0712	COG0835	chemotaxis
VCLMA_B0712	COG0784	Response regulator, receiver
VCLMA_B0714	COG3706	GGDEF domain
VCLMA_B0721	COG0583	DNA-binding transcription factor activity
VCLMA_B0722	COG5001	Diguanylate cyclase
VCLMA_B0724	COG1741	Belongs to the pirin family
VCLMA_B0725	COG3123	guanosine phosphorylase activity
VCLMA_B0727	COG2211	Major facilitator Superfamily
VCLMA_B0728	COG0840	transmembrane signaling receptor activity
VCLMA_B0730	COG1067	ATP-dependent peptidase activity
VCLMA_B0732	COG4172	Belongs to the ABC transporter superfamily
VCLMA_B0736	COG0583	DNA-binding transcription factor activity
VCLMA_B0737	COG1620	l-lactate permease
VCLMA_B0738	COG1304	FMN binding
VCLMA_B0740	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
VCLMA_B0742	COG0840	transmembrane signaling receptor activity
VCLMA_B0744	COG0513	Belongs to the DEAD box helicase family
VCLMA_B0746	COG0583	DNA-binding transcription factor activity
VCLMA_B0748	COG1902	pentaerythritol trinitrate reductase activity
VCLMA_B0750	COG1132	(ABC) transporter
VCLMA_B0753	COG1902	pentaerythritol trinitrate reductase activity
VCLMA_B0755	COG1280	lysine exporter protein (LysE YggA)
VCLMA_B0756	COG2207	Transcriptional regulator
VCLMA_B0760	COG1846	Transcriptional regulator
VCLMA_B0761	COG1764	response to oxidative stress
VCLMA_B0762	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCLMA_B0764	COG0697	spore germination
VCLMA_B0766	COG0700	Nucleoside recognition
VCLMA_B0767	COG3366	ferrous iron transmembrane transporter activity
VCLMA_B0768	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
VCLMA_B0770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VCLMA_B0771	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
VCLMA_B0772	COG2259	Doxx family
VCLMA_B0777	COG0363	glucosamine-6-phosphate deaminase activity
VCLMA_B0786	COG0840	transmembrane signaling receptor activity
VCLMA_B0788	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCLMA_B0789	COG1126	abc transporter atp-binding protein
VCLMA_B0791	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCLMA_B0792	COG4597	amino acid ABC transporter
VCLMA_B0793	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCLMA_B0794	COG2213	PTS system mannitol-specific
VCLMA_B0794	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCLMA_B0795	COG0246	Mannitol dehydrogenase
VCLMA_B0796	COG3722	fumarate hydratase activity
VCLMA_B0803	COG2910	NAD(P)H-binding
VCLMA_B0805	COG0840	transmembrane signaling receptor activity
VCLMA_B0806	COG4221	oxidoreductase activity
VCLMA_B0808	COG1901	pseudouridine methyltransferase
VCLMA_B0809	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VCLMA_B0811	COG0531	amino acid
VCLMA_B0812	COG1982	Orn Lys Arg decarboxylase major
VCLMA_B0820	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCLMA_B0825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VCLMA_B0827	COG0259	pyridoxamine-phosphate oxidase activity
VCLMA_B0833	COG0745	RESPONSE REGULATOR receiver
VCLMA_B0833	COG3706	GGDEF domain
VCLMA_B0837	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
VCLMA_B0838	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCLMA_B0839	COG0840	transmembrane signaling receptor activity
VCLMA_B0840	COG0835	chemotaxis
VCLMA_B0841	COG0835	chemotaxis
VCLMA_B0842	COG2198	Histidine kinase
VCLMA_B0842	COG0643	Histidine kinase
VCLMA_B0846	COG0601	transmembrane transport
VCLMA_B0847	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCLMA_B0849	COG2194	sulfuric ester hydrolase activity
VCLMA_B0851	COG0745	RESPONSE REGULATOR receiver
VCLMA_B0857	COG1444	tRNA N-acetyltransferase activity
VCLMA_B0858	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine