locus-tag	class	description
ASZ85_00001	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ASZ85_00002	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ASZ85_00003	COG0706	membrane insertase activity
ASZ85_00004	COG0594	ribonuclease P activity
ASZ85_00005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ASZ85_00006	COG1126	abc transporter atp-binding protein
ASZ85_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASZ85_00011	COG0592	DNA-directed DNA polymerase activity
ASZ85_00012	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ASZ85_00013	COG0187	DNA topoisomerase II activity
ASZ85_00016	COG0071	Belongs to the small heat shock protein (HSP20) family
ASZ85_00017	COG3977	Valine--pyruvate aminotransferase
ASZ85_00018	COG0751	glycine-tRNA ligase activity
ASZ85_00019	COG0752	glycyl-tRNA synthetase alpha subunit
ASZ85_00020	COG2119	membrane
ASZ85_00022	COG0425	Belongs to the sulfur carrier protein TusA family
ASZ85_00024	COG0604	alcohol dehydrogenase
ASZ85_00026	COG0129	dihydroxy-acid dehydratase activity
ASZ85_00027	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASZ85_00030	COG0606	chelatase, subunit chli
ASZ85_00040	COG0606	chelatase, subunit chli
ASZ85_00041	COG0204	Acyl-transferase
ASZ85_00042	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASZ85_00043	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ASZ85_00045	COG3084	Protein conserved in bacteria
ASZ85_00047	COG4326	sporulation control protein
ASZ85_00048	COG1272	protein, Hemolysin III
ASZ85_00050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASZ85_00051	COG0569	domain protein
ASZ85_00052	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ASZ85_00052	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASZ85_00053	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ASZ85_00054	COG0242	peptide deformylase activity
ASZ85_00055	COG1652	LysM domain
ASZ85_00056	COG0758	DNA mediated transformation
ASZ85_00057	COG2922	Belongs to the Smg family
ASZ85_00058	COG0551	DNA topoisomerase type I activity
ASZ85_00059	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ASZ85_00060	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ASZ85_00061	COG0009	L-threonylcarbamoyladenylate synthase
ASZ85_00062	COG0408	coproporphyrinogen oxidase activity
ASZ85_00063	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASZ85_00065	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ASZ85_00073	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASZ85_00074	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ASZ85_00076	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ASZ85_00077	COG2104	thiamine diphosphate biosynthetic process
ASZ85_00078	COG2022	thiamine diphosphate biosynthetic process
ASZ85_00079	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ASZ85_00080	COG0006	proline dipeptidase activity
ASZ85_00080	COG0006	proline dipeptidase activity
ASZ85_00084	COG1522	sequence-specific DNA binding
ASZ85_00085	COG5002	protein histidine kinase activity
ASZ85_00085	COG5001	Diguanylate cyclase
ASZ85_00086	COG0742	ribosomal rna small subunit methyltransferase
ASZ85_00088	COG0697	spore germination
ASZ85_00089	COG0589	response to stress
ASZ85_00090	COG1528	Iron-storage protein
ASZ85_00092	COG2081	HI0933 family
ASZ85_00094	COG1322	Protein conserved in bacteria
ASZ85_00095	COG2226	methyltransferase
ASZ85_00097	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASZ85_00098	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASZ85_00099	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASZ85_00100	COG0805	protein transport
ASZ85_00101	COG1858	cytochrome C peroxidase
ASZ85_00102	COG0534	Mate efflux family protein
ASZ85_00104	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ASZ85_00105	COG2937	Belongs to the GPAT DAPAT family
ASZ85_00106	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ASZ85_00107	COG3161	chorismate lyase activity
ASZ85_00108	COG1580	Controls the rotational direction of flagella during chemotaxis
ASZ85_00109	COG0840	transmembrane signaling receptor activity
ASZ85_00111	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASZ85_00112	COG0084	hydrolase, TatD family'
ASZ85_00117	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASZ85_00117	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASZ85_00118	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ASZ85_00121	COG3078	GTPase activator activity
ASZ85_00123	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASZ85_00124	COG3071	HemY protein
ASZ85_00125	COG2959	enzyme of heme biosynthesis
ASZ85_00126	COG1587	Uroporphyrinogen-III synthase
ASZ85_00127	COG0181	hydroxymethylbilane synthase activity
ASZ85_00129	COG3072	Adenylate cyclase
ASZ85_00130	COG1965	Belongs to the frataxin family
ASZ85_00132	COG0019	diaminopimelate decarboxylase activity
ASZ85_00133	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ASZ85_00135	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ASZ85_00136	COG1011	Hydrolase
ASZ85_00137	COG3287	FIST C domain
ASZ85_00137	COG2199	diguanylate cyclase activity
ASZ85_00137	COG2200	EAL domain
ASZ85_00140	COG0561	phosphatase activity
ASZ85_00141	COG2267	carboxylic ester hydrolase activity
ASZ85_00142	COG1280	lysine exporter protein (LysE YggA)
ASZ85_00143	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ASZ85_00145	COG0783	Belongs to the Dps family
ASZ85_00151	COG0742	ribosomal rna small subunit methyltransferase
ASZ85_00152	COG0552	protein localization to endoplasmic reticulum
ASZ85_00153	COG2884	Cell division ATP-binding protein ftsE
ASZ85_00154	COG2177	Part of the ABC transporter FtsEX involved in
ASZ85_00155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASZ85_00156	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASZ85_00159	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASZ85_00160	COG4206	TonB-dependent receptor
ASZ85_00161	COG1404	Belongs to the peptidase S8 family
ASZ85_00162	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ASZ85_00175	COG0583	DNA-binding transcription factor activity
ASZ85_00176	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ASZ85_00177	COG2960	long-chain fatty acid transporting porin activity
ASZ85_00178	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASZ85_00179	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ85_00180	COG1309	transcriptional regulator
ASZ85_00190	COG0747	negative chemotaxis
ASZ85_00192	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASZ85_00194	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASZ85_00195	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ASZ85_00197	COG0210	DNA helicase
ASZ85_00198	COG1280	lysine exporter protein (LysE YggA)
ASZ85_00201	COG2962	Rard protein
ASZ85_00203	COG0514	ATP-dependent DNA helicase (RecQ)
ASZ85_00206	COG1132	(ABC) transporter
ASZ85_00207	COG4774	siderophore transport
ASZ85_00208	COG1120	ATPase activity
ASZ85_00212	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ASZ85_00213	COG1263	PTS System
ASZ85_00213	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ85_00215	COG1561	YicC-like family, N-terminal region
ASZ85_00216	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ASZ85_00217	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ASZ85_00218	COG1560	Kdo2-lipid A biosynthetic process
ASZ85_00219	COG1560	Kdo2-lipid A biosynthetic process
ASZ85_00220	COG1309	transcriptional regulator
ASZ85_00222	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ASZ85_00226	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASZ85_00227	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ASZ85_00229	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ASZ85_00230	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ASZ85_00231	COG0859	PFAM glycosyl transferase family 9
ASZ85_00232	COG0463	Glycosyl transferase, family 2
ASZ85_00233	COG0859	PFAM glycosyl transferase family 9
ASZ85_00234	COG3642	lipopolysaccharide core region biosynthetic process
ASZ85_00240	COG1519	Transferase
ASZ85_00247	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASZ85_00248	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ASZ85_00248	COG0662	Cupin 2, conserved barrel domain protein
ASZ85_00249	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASZ85_00250	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ASZ85_00256	COG0318	PFAM AMP-dependent synthetase and ligase
ASZ85_00257	COG1012	belongs to the aldehyde dehydrogenase family
ASZ85_00257	COG1454	alcohol dehydrogenase
ASZ85_00260	COG5433	transposase activity
ASZ85_00261	COG5433	transposase activity
ASZ85_00266	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASZ85_00268	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ASZ85_00269	COG0668	transmembrane transport
ASZ85_00270	COG1573	uracil-dna glycosylase
ASZ85_00272	COG3068	Protein conserved in bacteria
ASZ85_00274	COG1940	carbohydrate kinase activity
ASZ85_00275	COG1253	flavin adenine dinucleotide binding
ASZ85_00276	COG0776	regulation of translation
ASZ85_00278	COG0151	Belongs to the GarS family
ASZ85_00279	COG0138	bifunctional purine biosynthesis protein purh
ASZ85_00281	COG0789	Transcriptional regulator
ASZ85_00282	COG3710	Transcriptional regulator
ASZ85_00284	COG0531	amino acid
ASZ85_00285	COG1982	Orn Lys Arg decarboxylase major
ASZ85_00286	COG0840	transmembrane signaling receptor activity
ASZ85_00289	COG0800	Aldolase
ASZ85_00290	COG2610	gluconate transmembrane transporter activity
ASZ85_00291	COG3265	gluconokinase activity
ASZ85_00292	COG0129	dihydroxy-acid dehydratase activity
ASZ85_00293	COG1609	Transcriptional regulator
ASZ85_00294	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ASZ85_00295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASZ85_00297	COG0439	Biotin carboxylase
ASZ85_00298	COG0511	ligase activity, forming carbon-carbon bonds
ASZ85_00299	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ASZ85_00300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASZ85_00303	COG2814	Major facilitator Superfamily
ASZ85_00304	COG2205	protein histidine kinase activity
ASZ85_00304	COG0784	Response regulator, receiver
ASZ85_00305	COG0248	Ppx GppA phosphatase
ASZ85_00306	COG0513	Belongs to the DEAD box helicase family
ASZ85_00307	COG3118	belongs to the thioredoxin family
ASZ85_00308	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ASZ85_00310	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASZ85_00319	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASZ85_00321	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ASZ85_00323	COG1072	(Pantothenic acid kinase))
ASZ85_00328	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASZ85_00329	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASZ85_00330	COG0250	Participates in transcription elongation, termination and antitermination
ASZ85_00331	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ASZ85_00332	COG0081	regulation of translation
ASZ85_00333	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ASZ85_00334	COG0222	ribosome binding
ASZ85_00335	COG0085	RNA polymerase activity
ASZ85_00336	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ASZ85_00337	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
ASZ85_00338	COG2816	NAD+ diphosphatase activity
ASZ85_00339	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ASZ85_00342	COG4942	peptidase
ASZ85_00343	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ASZ85_00345	COG0471	metal ion transport
ASZ85_00346	COG0688	phosphatidylethanolamine metabolic process
ASZ85_00347	COG1162	GTPase activity
ASZ85_00348	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ASZ85_00358	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ASZ85_00359	COG0802	atpase or kinase
ASZ85_00361	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ASZ85_00362	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ASZ85_00363	COG1923	regulation of RNA biosynthetic process
ASZ85_00364	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ASZ85_00365	COG0330	HflC and HflK could
ASZ85_00366	COG0330	HflC and HflK could
ASZ85_00367	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ASZ85_00368	COG2900	Belongs to the SlyX family
ASZ85_00370	COG0545	Peptidyl-prolyl cis-trans isomerase
ASZ85_00371	COG2964	Protein conserved in bacteria
ASZ85_00372	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ASZ85_00373	COG2923	Belongs to the DsrF TusC family
ASZ85_00375	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ASZ85_00376	COG0049	tRNA binding
ASZ85_00377	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASZ85_00378	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASZ85_00379	COG2906	2 iron, 2 sulfur cluster binding
ASZ85_00381	COG0360	Binds together with S18 to 16S ribosomal RNA
ASZ85_00382	COG2965	DNA replication, synthesis of RNA primer
ASZ85_00383	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ASZ85_00384	COG0359	binds to the 23S rRNA
ASZ85_00386	COG0305	Participates in initiation and elongation during chromosome replication
ASZ85_00387	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASZ85_00388	COG0432	Pfam Uncharacterised protein family UPF0047
ASZ85_00389	COG0166	Belongs to the GPI family
ASZ85_00392	COG0735	belongs to the Fur family
ASZ85_00393	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASZ85_00399	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ASZ85_00400	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASZ85_00401	COG0175	sulfate reduction
ASZ85_00410	COG1410	methionine synthase
ASZ85_00410	COG0646	methionine synthase
ASZ85_00411	COG0527	aspartate kinase activity
ASZ85_00412	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ASZ85_00414	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ASZ85_00417	COG0629	single-stranded DNA binding
ASZ85_00418	COG2199	diguanylate cyclase activity
ASZ85_00418	COG2200	EAL domain
ASZ85_00423	COG3267	Type II secretory pathway component ExeA
ASZ85_00423	COG3409	Peptidoglycan-binding domain 1 protein
ASZ85_00425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASZ85_00427	COG1459	type II secretion system
ASZ85_00436	COG1077	Cell shape determining protein MreB Mrl
ASZ85_00437	COG1792	Involved in formation and maintenance of cell shape
ASZ85_00438	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ASZ85_00439	COG0424	maF-like protein
ASZ85_00440	COG1530	ribonuclease E activity
ASZ85_00441	COG3164	Protein of unknown function
ASZ85_00442	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASZ85_00443	COG0312	modulator of DNA gyrase
ASZ85_00444	COG2235	arginine
ASZ85_00448	COG0589	response to stress
ASZ85_00451	COG1438	arginine binding
ASZ85_00452	COG0039	L-malate dehydrogenase activity
ASZ85_00453	COG0531	amino acid
ASZ85_00454	COG0142	geranyltranstransferase activity
ASZ85_00455	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ASZ85_00456	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ASZ85_00457	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ASZ85_00458	COG2966	Psort location CytoplasmicMembrane, score
ASZ85_00459	COG3610	response to peptide
ASZ85_00461	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASZ85_00462	COG2967	ApaG domain
ASZ85_00463	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ASZ85_00464	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ASZ85_00465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASZ85_00466	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ASZ85_00467	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASZ85_00478	COG0741	lytic transglycosylase activity
ASZ85_00479	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ASZ85_00480	COG1194	a g-specific adenine glycosylase
ASZ85_00482	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASZ85_00483	COG2066	Belongs to the glutaminase family
ASZ85_00485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASZ85_00486	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ASZ85_00489	COG0762	integral membrane protein
ASZ85_00490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ASZ85_00491	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ASZ85_00495	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASZ85_00496	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ASZ85_00497	COG1678	Uncharacterized ACR, COG1678
ASZ85_00498	COG0189	ligase activity
ASZ85_00499	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASZ85_00500	COG2356	endonuclease I
ASZ85_00501	COG3091	SprT-like family
ASZ85_00502	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ASZ85_00504	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASZ85_00505	COG0583	DNA-binding transcription factor activity
ASZ85_00506	COG4771	TonB-dependent receptor
ASZ85_00507	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASZ85_00508	COG0126	phosphoglycerate kinase activity
ASZ85_00509	COG0191	fructose-bisphosphate aldolase activity
ASZ85_00510	COG0668	transmembrane transport
ASZ85_00511	COG1279	arginine transmembrane transporter activity
ASZ85_00512	COG0583	DNA-binding transcription factor activity
ASZ85_00515	COG0469	pyruvate kinase activity
ASZ85_00516	COG1349	DNA-binding transcription factor activity
ASZ85_00517	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ASZ85_00518	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASZ85_00521	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASZ85_00522	COG0358	DNA primase activity
ASZ85_00523	COG1610	YqeY-like protein
ASZ85_00524	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ASZ85_00526	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ASZ85_00528	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASZ85_00529	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ASZ85_00530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ASZ85_00531	COG1968	undecaprenyl-diphosphatase activity
ASZ85_00532	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ASZ85_00533	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ASZ85_00534	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ASZ85_00535	COG0585	pseudouridine synthase activity
ASZ85_00536	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ASZ85_00537	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ASZ85_00538	COG4942	peptidase
ASZ85_00538	COG1388	LysM domain
ASZ85_00539	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASZ85_00540	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ASZ85_00544	COG4208	sulfate ABC transporter
ASZ85_00545	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ASZ85_00547	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ASZ85_00548	COG2137	regulation of response to DNA damage stimulus
ASZ85_00549	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ASZ85_00551	COG0527	aspartate kinase activity
ASZ85_00552	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ASZ85_00561	COG3630	sodium ion export across plasma membrane
ASZ85_00562	COG5016	pyruvate
ASZ85_00562	COG0511	ligase activity, forming carbon-carbon bonds
ASZ85_00563	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ASZ85_00565	COG1238	metal cluster binding
ASZ85_00566	COG0612	Peptidase, M16
ASZ85_00567	COG2918	glutathione biosynthetic process
ASZ85_00568	COG1854	S-ribosylhomocysteine lyase activity
ASZ85_00569	COG4536	flavin adenine dinucleotide binding
ASZ85_00570	COG4137	Cytochrome C assembly protein
ASZ85_00571	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ASZ85_00572	COG0228	four-way junction DNA binding
ASZ85_00573	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ASZ85_00574	COG0336	Belongs to the RNA methyltransferase TrmD family
ASZ85_00575	COG0335	large ribosomal subunit rRNA binding
ASZ85_00576	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASZ85_00577	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASZ85_00579	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ASZ85_00580	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ASZ85_00581	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ASZ85_00582	COG0723	plastoquinol--plastocyanin reductase activity
ASZ85_00583	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ASZ85_00584	COG2857	Cytochrome c1
ASZ85_00585	COG0625	glutathione transferase activity
ASZ85_00586	COG2969	positive regulation of protein catabolic process
ASZ85_00587	COG2823	Periplasmic or secreted lipoprotein
ASZ85_00588	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ASZ85_00589	COG0792	nuclease activity
ASZ85_00590	COG3107	peptidoglycan biosynthetic process
ASZ85_00591	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ASZ85_00594	COG0288	reversible hydration of carbon dioxide
ASZ85_00595	COG0659	secondary active sulfate transmembrane transporter activity
ASZ85_00596	COG1131	(ABC) transporter
ASZ85_00597	COG0842	Transport permease protein
ASZ85_00598	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ASZ85_00599	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ASZ85_00600	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ASZ85_00602	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASZ85_00603	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ASZ85_00604	COG1489	DNA binding
ASZ85_00606	COG1643	Atp-dependent helicase
ASZ85_00607	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASZ85_00608	COG1752	Esterase of the alpha-beta hydrolase superfamily
ASZ85_00609	COG1049	propionate catabolic process, 2-methylcitrate cycle
ASZ85_00610	COG3112	Uncharacterised protein family (UPF0231)
ASZ85_00611	COG0347	Belongs to the P(II) protein family
ASZ85_00612	COG0004	ammonium transporteR
ASZ85_00613	COG1840	ABC-type Fe3 transport system, periplasmic component
ASZ85_00615	COG3842	ATPase activity
ASZ85_00619	COG2971	BadF BadG BcrA BcrD
ASZ85_00621	COG4608	Belongs to the ABC transporter superfamily
ASZ85_00622	COG0444	Belongs to the ABC transporter superfamily
ASZ85_00623	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASZ85_00624	COG0601	transmembrane transport
ASZ85_00625	COG0747	negative chemotaxis
ASZ85_00627	COG2813	Specifically methylates the guanine in position
ASZ85_00628	COG0628	permease
ASZ85_00630	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ASZ85_00632	COG0316	Belongs to the HesB IscA family
ASZ85_00635	COG0739	heme binding
ASZ85_00636	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASZ85_00637	COG2027	D-alanyl-D-alanine carboxypeptidase
ASZ85_00638	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASZ85_00639	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASZ85_00640	COG1534	Rna-binding protein
ASZ85_00641	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ASZ85_00642	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASZ85_00643	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ASZ85_00644	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASZ85_00645	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASZ85_00648	COG0779	Required for maturation of 30S ribosomal subunits
ASZ85_00649	COG0195	Participates in both transcription termination and antitermination
ASZ85_00650	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ASZ85_00651	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASZ85_00652	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ASZ85_00653	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ASZ85_00654	COG1185	polyribonucleotide nucleotidyltransferase activity
ASZ85_00655	COG4785	May be involved in cell division
ASZ85_00662	COG3153	acetyltransferase
ASZ85_00666	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ASZ85_00667	COG0513	Belongs to the DEAD box helicase family
ASZ85_00668	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ASZ85_00670	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ASZ85_00671	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASZ85_00672	COG2204	response regulator
ASZ85_00676	COG0667	Aldo Keto reductase
ASZ85_00677	COG3066	DNA modification
ASZ85_00680	COG0494	nUDIX hydrolase
ASZ85_00681	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ASZ85_00682	COG0730	response to heat
ASZ85_00683	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ASZ85_00684	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ASZ85_00685	COG1283	sodium-dependent phosphate transmembrane transporter activity
ASZ85_00686	COG0583	DNA-binding transcription factor activity
ASZ85_00687	COG0640	Transcriptional regulator
ASZ85_00688	COG0268	Binds directly to 16S ribosomal RNA
ASZ85_00689	COG0728	peptidoglycan biosynthetic process
ASZ85_00690	COG0196	riboflavin kinase activity
ASZ85_00691	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ASZ85_00692	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ASZ85_00693	COG1047	Peptidyl-prolyl cis-trans
ASZ85_00694	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ASZ85_00695	COG1966	Carbon starvation protein
ASZ85_00698	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ASZ85_00699	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ASZ85_00700	COG1472	Belongs to the glycosyl hydrolase 3 family
ASZ85_00701	COG3279	Response regulator of the LytR AlgR family
ASZ85_00702	COG3275	phosphorelay sensor kinase activity
ASZ85_00703	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASZ85_00704	COG0287	Prephenate dehydrogenase
ASZ85_00704	COG1605	Chorismate mutase
ASZ85_00706	COG0488	(ABC) transporter
ASZ85_00708	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
ASZ85_00709	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
ASZ85_00710	COG5001	Diguanylate cyclase
ASZ85_00711	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASZ85_00712	COG0077	Prephenate dehydratase
ASZ85_00712	COG1605	Chorismate mutase
ASZ85_00713	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ASZ85_00715	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASZ85_00716	COG0564	pseudouridine synthase activity
ASZ85_00718	COG0542	response to heat
ASZ85_00726	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASZ85_00728	COG2974	May be involved in recombination
ASZ85_00729	COG0745	RESPONSE REGULATOR receiver
ASZ85_00730	COG5002	protein histidine kinase activity
ASZ85_00732	COG0248	Ppx GppA phosphatase
ASZ85_00733	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ASZ85_00735	COG0581	inorganic phosphate transmembrane transporter activity
ASZ85_00736	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASZ85_00739	COG3142	Participates in the control of copper homeostasis
ASZ85_00740	COG0450	alkyl hydroperoxide reductase
ASZ85_00741	COG0583	DNA-binding transcription factor activity
ASZ85_00742	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ASZ85_00744	COG0517	IMP dehydrogenase activity
ASZ85_00745	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ASZ85_00746	COG0343	queuine tRNA-ribosyltransferase activity
ASZ85_00747	COG1862	Preprotein translocase
ASZ85_00748	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASZ85_00749	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASZ85_00750	COG0483	inositol monophosphate 1-phosphatase activity
ASZ85_00752	COG1959	2 iron, 2 sulfur cluster binding
ASZ85_00753	COG1104	cysteine desulfurase activity
ASZ85_00754	COG0822	iron-sulfur transferase activity
ASZ85_00755	COG0316	Belongs to the HesB IscA family
ASZ85_00756	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASZ85_00757	COG0443	Heat shock 70 kDa protein
ASZ85_00758	COG0633	Ferredoxin
ASZ85_00759	COG2975	iron-sulfur cluster assembly
ASZ85_00760	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASZ85_00761	COG0105	UTP biosynthetic process
ASZ85_00762	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ASZ85_00764	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ASZ85_00765	COG0124	histidyl-tRNA synthetase
ASZ85_00766	COG2976	Protein conserved in bacteria
ASZ85_00767	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASZ85_00768	COG1160	GTP binding
ASZ85_00771	COG1570	exodeoxyribonuclease VII activity
ASZ85_00772	COG0517	IMP dehydrogenase activity
ASZ85_00772	COG0516	GMP reductase activity
ASZ85_00773	COG0519	Catalyzes the synthesis of GMP from XMP
ASZ85_00773	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASZ85_00775	COG1584	GPR1 FUN34 yaaH family protein
ASZ85_00776	COG3433	isochorismatase activity
ASZ85_00776	COG1535	isochorismatase
ASZ85_00777	COG1021	2,3-dihydroxybenzoate-AMP ligase
ASZ85_00778	COG1169	isochorismate synthase
ASZ85_00779	COG1028	Short-chain dehydrogenase reductase Sdr
ASZ85_00781	COG4592	Periplasmic binding protein
ASZ85_00782	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASZ85_00783	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASZ85_00784	COG1120	ATPase activity
ASZ85_00786	COG0583	DNA-binding transcription factor activity
ASZ85_00787	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ASZ85_00788	COG1115	amino acid carrier protein
ASZ85_00789	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASZ85_00790	COG0583	DNA-binding transcription factor activity
ASZ85_00793	COG4565	transcriptional regulatory protein
ASZ85_00795	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ASZ85_00796	COG5016	pyruvate
ASZ85_00796	COG0511	ligase activity, forming carbon-carbon bonds
ASZ85_00797	COG3630	sodium ion export across plasma membrane
ASZ85_00799	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ASZ85_00800	COG3052	prosthetic group binding
ASZ85_00801	COG2301	Belongs to the HpcH HpaI aldolase family
ASZ85_00802	COG3051	citrate lyase alpha subunit
ASZ85_00803	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
ASZ85_00804	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ASZ85_00806	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASZ85_00807	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ASZ85_00808	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ASZ85_00820	COG1012	belongs to the aldehyde dehydrogenase family
ASZ85_00824	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ASZ85_00825	COG0840	transmembrane signaling receptor activity
ASZ85_00826	COG3710	Transcriptional regulator
ASZ85_00828	COG2165	general secretion pathway protein
ASZ85_00831	COG4796	Type ii and iii secretion system protein
ASZ85_00835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASZ85_00836	COG1459	type II secretion system
ASZ85_00838	COG2207	Transcriptional regulator
ASZ85_00839	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ASZ85_00842	COG0739	heme binding
ASZ85_00844	COG3064	Membrane
ASZ85_00846	COG0582	viral genome integration into host DNA
ASZ85_00847	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ASZ85_00848	COG2867	negative regulation of translational initiation
ASZ85_00849	COG2914	Belongs to the UPF0125 (RnfH) family
ASZ85_00850	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASZ85_00851	COG0497	DNA recombination
ASZ85_00852	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ASZ85_00853	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ASZ85_00855	COG0443	Heat shock 70 kDa protein
ASZ85_00856	COG0484	heat shock protein binding
ASZ85_00862	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ASZ85_00863	COG0590	tRNA wobble adenosine to inosine editing
ASZ85_00865	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ASZ85_00868	COG0047	phosphoribosylformylglycinamidine synthase activity
ASZ85_00868	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASZ85_00872	COG0442	prolyl-tRNA aminoacylation
ASZ85_00873	COG1720	tRNA m6t6A37 methyltransferase activity
ASZ85_00874	COG0254	rRNA binding
ASZ85_00875	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ASZ85_00876	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ASZ85_00877	COG1671	Belongs to the UPF0178 family
ASZ85_00879	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ85_00882	COG3098	single-species biofilm formation
ASZ85_00883	COG0564	pseudouridine synthase activity
ASZ85_00884	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ASZ85_00885	COG0142	geranyltranstransferase activity
ASZ85_00886	COG1722	exodeoxyribonuclease VII activity
ASZ85_00887	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ASZ85_00889	COG0301	tRNA thio-modification
ASZ85_00889	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASZ85_00890	COG0583	DNA-binding transcription factor activity
ASZ85_00891	COG2363	Small membrane protein
ASZ85_00892	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASZ85_00893	COG1611	Belongs to the LOG family
ASZ85_00894	COG3706	GGDEF domain
ASZ85_00896	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASZ85_00896	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASZ85_00898	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
ASZ85_00899	COG1464	Belongs to the NlpA lipoprotein family
ASZ85_00900	COG2011	ABC-type metal ion transport system permease component
ASZ85_00901	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASZ85_00902	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASZ85_00903	COG1609	Transcriptional regulator
ASZ85_00904	COG1263	PTS System
ASZ85_00904	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ85_00905	COG0366	Alpha amylase catalytic
ASZ85_00911	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASZ85_00912	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASZ85_00913	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ASZ85_00914	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ASZ85_00915	COG0110	maltose O-acetyltransferase activity
ASZ85_00919	COG1045	serine acetyltransferase
ASZ85_00921	COG0438	transferase activity, transferring glycosyl groups
ASZ85_00923	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ASZ85_00929	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASZ85_00931	COG1596	polysaccharide export
ASZ85_00937	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASZ85_00939	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ASZ85_00940	COG0321	lipoyl(octanoyl) transferase activity
ASZ85_00941	COG2921	Belongs to the UPF0250 family
ASZ85_00942	COG1686	Belongs to the peptidase S11 family
ASZ85_00943	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ASZ85_00944	COG0772	Belongs to the SEDS family
ASZ85_00945	COG0768	penicillin binding
ASZ85_00946	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ASZ85_00947	COG0799	negative regulation of ribosome biogenesis
ASZ85_00948	COG1466	dna polymerase III delta subunit
ASZ85_00949	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ASZ85_00950	COG0495	leucyl-tRNA aminoacylation
ASZ85_00951	COG2888	peptidyl-tyrosine sulfation
ASZ85_00952	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ASZ85_00953	COG4535	Mg2 and Co2 transporter CorC
ASZ85_00954	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ASZ85_00955	COG1702	phosphate starvation-inducible protein PhoH
ASZ85_00956	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASZ85_00957	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASZ85_00958	COG2190	(PTS) system
ASZ85_00960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ85_00961	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ASZ85_00962	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ASZ85_00963	COG3115	cell septum assembly
ASZ85_00964	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASZ85_00967	COG0789	Transcriptional regulator
ASZ85_00968	COG1585	Membrane protein implicated in regulation of membrane protease activity
ASZ85_00969	COG0330	HflC and HflK could
ASZ85_00970	COG3118	belongs to the thioredoxin family
ASZ85_00972	COG0300	oxidoreductase activity
ASZ85_00973	COG1090	epimerase
ASZ85_00974	COG0622	Phosphoesterase
ASZ85_00977	COG3710	Transcriptional regulator
ASZ85_00978	COG0326	Molecular chaperone. Has ATPase activity
ASZ85_00979	COG0563	adenylate kinase activity
ASZ85_00980	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ASZ85_00984	COG0367	asparagine synthase
ASZ85_00985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASZ85_00985	COG4651	solute:proton antiporter activity
ASZ85_00986	COG1846	Transcriptional regulator
ASZ85_00986	COG1940	carbohydrate kinase activity
ASZ85_00987	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ASZ85_00988	COG1263	PTS System
ASZ85_00988	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ85_00988	COG2190	(PTS) system
ASZ85_00989	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASZ85_00992	COG0101	tRNA pseudouridine synthase activity
ASZ85_00993	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ASZ85_00994	COG0285	dihydrofolate synthase activity
ASZ85_00995	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ASZ85_00996	COG1286	toxin biosynthetic process
ASZ85_00997	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ASZ85_00998	COG2056	Na+-H+ antiporter family
ASZ85_00999	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASZ85_01003	COG0346	lactoylglutathione lyase activity
ASZ85_01004	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ASZ85_01005	COG4660	Part of a membrane complex involved in electron transport
ASZ85_01006	COG4659	FMN binding
ASZ85_01007	COG4658	electron transport chain
ASZ85_01008	COG4656	Part of a membrane complex involved in electron transport
ASZ85_01009	COG2878	Part of a membrane complex involved in electron transport
ASZ85_01010	COG4657	Part of a membrane complex involved in electron transport
ASZ85_01013	COG0556	nucleotide-excision repair
ASZ85_01014	COG2204	response regulator
ASZ85_01015	COG2198	Histidine kinase
ASZ85_01016	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ASZ85_01017	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ASZ85_01018	COG0521	Mo-molybdopterin cofactor biosynthetic process
ASZ85_01019	COG0315	cyclic pyranopterin monophosphate synthase activity
ASZ85_01020	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ASZ85_01021	COG0314	molybdopterin synthase activity
ASZ85_01022	COG2199	diguanylate cyclase activity
ASZ85_01023	COG4109	DRTGG domain
ASZ85_01025	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ASZ85_01027	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASZ85_01027	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASZ85_01028	COG0489	protein tyrosine kinase activity
ASZ85_01029	COG0572	uridine kinase
ASZ85_01030	COG2982	Protein involved in outer membrane biogenesis
ASZ85_01031	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ASZ85_01032	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASZ85_01034	COG2067	long-chain fatty acid transport protein
ASZ85_01037	COG0183	Belongs to the thiolase family
ASZ85_01038	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASZ85_01038	COG1024	Enoyl-CoA hydratase
ASZ85_01039	COG0778	Nitroreductase
ASZ85_01040	COG0583	DNA-binding transcription factor activity
ASZ85_01041	COG0745	RESPONSE REGULATOR receiver
ASZ85_01044	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASZ85_01046	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ASZ85_01047	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ASZ85_01050	COG1028	Short-chain dehydrogenase reductase Sdr
ASZ85_01051	COG0616	signal peptide processing
ASZ85_01053	COG1522	sequence-specific DNA binding
ASZ85_01054	COG1946	Acyl-CoA thioesterase
ASZ85_01058	COG3706	GGDEF domain
ASZ85_01059	COG0640	Transcriptional regulator
ASZ85_01060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASZ85_01066	COG1881	PFAM PEBP family protein
ASZ85_01070	COG0009	L-threonylcarbamoyladenylate synthase
ASZ85_01073	COG2201	protein-glutamate methylesterase activity
ASZ85_01075	COG5002	protein histidine kinase activity
ASZ85_01076	COG4191	Histidine kinase
ASZ85_01077	COG3300	MHYT domain
ASZ85_01077	COG5001	Diguanylate cyclase
ASZ85_01078	COG2204	response regulator
ASZ85_01082	COG0601	transmembrane transport
ASZ85_01083	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASZ85_01084	COG0444	Belongs to the ABC transporter superfamily
ASZ85_01085	COG4608	Belongs to the ABC transporter superfamily
ASZ85_01086	COG0435	Glutathione S-transferase
ASZ85_01087	COG0857	belongs to the CobB CobQ family
ASZ85_01087	COG0280	phosphate acetyltransferase
ASZ85_01088	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASZ85_01089	COG3092	negative regulation of chromosome organization
ASZ85_01090	COG4628	conserved protein (DUF2132)
ASZ85_01092	COG4120	Belongs to the binding-protein-dependent transport system permease family
ASZ85_01094	COG2199	diguanylate cyclase activity
ASZ85_01094	COG2203	Gaf domain
ASZ85_01095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASZ85_01097	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ASZ85_01098	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASZ85_01099	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ASZ85_01100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASZ85_01101	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ASZ85_01102	COG0156	8-amino-7-oxononanoate synthase activity
ASZ85_01103	COG2226	methyltransferase
ASZ85_01104	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ASZ85_01106	COG0501	Belongs to the peptidase M48B family
ASZ85_01107	COG0501	Belongs to the peptidase M48B family
ASZ85_01109	COG0300	oxidoreductase activity
ASZ85_01112	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASZ85_01114	COG2268	Band 7 protein
ASZ85_01116	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASZ85_01117	COG2915	High frequency lysogenization protein hflD homolog
ASZ85_01118	COG0482	sulfurtransferase activity
ASZ85_01119	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASZ85_01120	COG2916	Histone family protein nucleoid-structuring protein H-NS
ASZ85_01121	COG1757	Na H antiporter
ASZ85_01122	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ASZ85_01123	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ASZ85_01124	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASZ85_01125	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASZ85_01125	COG0131	Imidazoleglycerol-phosphate dehydratase
ASZ85_01126	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ASZ85_01127	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ASZ85_01128	COG0107	imidazoleglycerol-phosphate synthase activity
ASZ85_01129	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ASZ85_01129	COG0140	phosphoribosyl-ATP diphosphatase activity
ASZ85_01130	COG1187	pseudouridine synthase activity
ASZ85_01132	COG1278	Cold shock
ASZ85_01133	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ASZ85_01134	COG0542	response to heat
ASZ85_01136	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASZ85_01137	COG1454	alcohol dehydrogenase
ASZ85_01137	COG1012	belongs to the aldehyde dehydrogenase family
ASZ85_01138	COG1737	Transcriptional regulator
ASZ85_01139	COG0076	glutamate decarboxylase activity
ASZ85_01141	COG2431	L-lysine efflux transmembrane transporter activity
ASZ85_01143	COG3070	regulator of competence-specific genes
ASZ85_01146	COG3852	Histidine kinase
ASZ85_01148	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ASZ85_01151	COG4067	protein conserved in archaea
ASZ85_01151	COG0189	ligase activity
ASZ85_01152	COG0500	methyltransferase
ASZ85_01153	COG4106	trans-aconitate 2-methyltransferase activity
ASZ85_01154	COG1801	Protein of unknown function DUF72
ASZ85_01155	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ASZ85_01156	COG1435	thymidine kinase activity
ASZ85_01158	COG0159	tryptophan synthase activity
ASZ85_01159	COG0133	tryptophan synthase activity
ASZ85_01160	COG0134	indole-3-glycerol-phosphate synthase activity
ASZ85_01160	COG0135	phosphoribosylanthranilate isomerase activity
ASZ85_01161	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASZ85_01162	COG0512	Glutamine amidotransferase of anthranilate synthase
ASZ85_01163	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASZ85_01165	COG0613	PHP domain protein
ASZ85_01166	COG0009	L-threonylcarbamoyladenylate synthase
ASZ85_01167	COG1187	pseudouridine synthase activity
ASZ85_01168	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ASZ85_01169	COG4988	ABC transporter
ASZ85_01170	COG0492	ferredoxin-NADP+ reductase activity
ASZ85_01172	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASZ85_01173	COG3706	GGDEF domain
ASZ85_01174	COG2949	membrane
ASZ85_01176	COG0281	malic enzyme
ASZ85_01178	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ASZ85_01182	COG2885	chlorophyll binding
ASZ85_01185	COG0247	lactate metabolic process
ASZ85_01185	COG0277	FAD linked oxidase domain protein
ASZ85_01189	COG2986	histidine ammonia-lyase
ASZ85_01190	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ASZ85_01191	COG0010	Belongs to the arginase family
ASZ85_01192	COG1228	amidohydrolase
ASZ85_01196	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASZ85_01198	COG5001	Diguanylate cyclase
ASZ85_01199	COG0417	DNA replication proofreading
ASZ85_01200	COG2197	response regulator
ASZ85_01201	COG0322	excinuclease ABC activity
ASZ85_01207	COG3706	GGDEF domain
ASZ85_01207	COG0745	RESPONSE REGULATOR receiver
ASZ85_01210	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ASZ85_01211	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASZ85_01211	COG0072	phenylalanine-tRNA ligase activity
ASZ85_01213	COG0776	regulation of translation
ASZ85_01215	COG0500	methyltransferase
ASZ85_01216	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ASZ85_01218	COG0295	cytidine deaminase activity
ASZ85_01219	COG1346	cytolysis
ASZ85_01221	COG2925	Exonuclease
ASZ85_01223	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ85_01225	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ASZ85_01226	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ASZ85_01229	COG2988	succinylglutamate desuccinylase activity
ASZ85_01230	COG4139	cobalamin transport
ASZ85_01231	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
ASZ85_01240	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASZ85_01241	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASZ85_01242	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASZ85_01246	COG2814	Major facilitator Superfamily
ASZ85_01248	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASZ85_01253	COG2989	Protein conserved in bacteria
ASZ85_01254	COG3108	Peptidase M15
ASZ85_01255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASZ85_01258	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASZ85_01263	COG1846	Transcriptional regulator
ASZ85_01264	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASZ85_01265	COG0726	polysaccharide deacetylase
ASZ85_01266	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASZ85_01268	COG1447	Phosphotransferase system cellobiose-specific component IIA
ASZ85_01269	COG1486	melibiose metabolic process
ASZ85_01270	COG3394	polysaccharide catabolic process
ASZ85_01271	COG1609	Transcriptional regulator
ASZ85_01272	COG2943	transferase activity, transferring hexosyl groups
ASZ85_01273	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ASZ85_01274	COG0840	transmembrane signaling receptor activity
ASZ85_01277	COG1448	Aminotransferase
ASZ85_01279	COG2770	Histidine kinase
ASZ85_01279	COG3437	response regulator, receiver
ASZ85_01280	COG0351	phosphomethylpyrimidine kinase
ASZ85_01281	COG0017	Asparaginyl-tRNA synthetase
ASZ85_01282	COG0840	transmembrane signaling receptor activity
ASZ85_01283	COG0720	synthase
ASZ85_01284	COG1760	l-serine dehydratase
ASZ85_01285	COG0814	amino acid
ASZ85_01286	COG0494	nUDIX hydrolase
ASZ85_01287	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASZ85_01290	COG3106	COG3106 Predicted ATPase
ASZ85_01291	COG3768	UPF0283 membrane protein
ASZ85_01292	COG3283	Transcriptional regulator of aromatic amino acids metabolism
ASZ85_01293	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ85_01296	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASZ85_01298	COG0471	metal ion transport
ASZ85_01299	COG4191	Histidine kinase
ASZ85_01299	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASZ85_01301	COG2990	Protein conserved in bacteria
ASZ85_01302	COG3713	MltA-interacting MipA family protein
ASZ85_01303	COG2205	protein histidine kinase activity
ASZ85_01304	COG0745	RESPONSE REGULATOR receiver
ASZ85_01310	COG1129	ABC transporter
ASZ85_01317	COG2186	Transcriptional regulator
ASZ85_01318	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ASZ85_01319	COG0372	Belongs to the citrate synthase family
ASZ85_01325	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASZ85_01327	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ASZ85_01329	COG0625	glutathione transferase activity
ASZ85_01330	COG3437	response regulator, receiver
ASZ85_01331	COG3437	response regulator, receiver
ASZ85_01331	COG2205	protein histidine kinase activity
ASZ85_01331	COG3850	Histidine kinase
ASZ85_01331	COG4999	Histidine kinase
ASZ85_01333	COG3706	GGDEF domain
ASZ85_01334	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ASZ85_01335	COG1254	Belongs to the acylphosphatase family
ASZ85_01336	COG2920	part of a sulfur-relay system
ASZ85_01337	COG0670	Belongs to the BI1 family
ASZ85_01338	COG1126	abc transporter atp-binding protein
ASZ85_01339	COG0765	amino acid transport
ASZ85_01340	COG4597	amino acid ABC transporter
ASZ85_01341	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASZ85_01343	COG0561	phosphatase activity
ASZ85_01344	COG0602	queuosine metabolic process
ASZ85_01345	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ASZ85_01351	COG3706	GGDEF domain
ASZ85_01352	COG0443	Heat shock 70 kDa protein
ASZ85_01353	COG0443	Heat shock 70 kDa protein
ASZ85_01361	COG1643	Atp-dependent helicase
ASZ85_01363	COG0443	Heat shock 70 kDa protein
ASZ85_01364	COG0095	Lipoate-protein ligase
ASZ85_01366	COG0583	DNA-binding transcription factor activity
ASZ85_01367	COG0477	Major facilitator Superfamily
ASZ85_01368	COG0415	Belongs to the DNA photolyase family
ASZ85_01369	COG2076	Multidrug Resistance protein
ASZ85_01373	COG2198	Histidine kinase
ASZ85_01373	COG0643	Histidine kinase
ASZ85_01375	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASZ85_01377	COG2201	protein-glutamate methylesterase activity
ASZ85_01378	COG0835	chemotaxis
ASZ85_01379	COG0840	transmembrane signaling receptor activity
ASZ85_01379	COG3290	protein histidine kinase activity
ASZ85_01381	COG0840	transmembrane signaling receptor activity
ASZ85_01383	COG0513	Belongs to the DEAD box helicase family
ASZ85_01385	COG1538	Outer membrane efflux protein
ASZ85_01386	COG1566	PFAM secretion protein HlyD family protein
ASZ85_01387	COG2814	Major facilitator Superfamily
ASZ85_01388	COG0840	transmembrane signaling receptor activity
ASZ85_01389	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ASZ85_01391	COG3501	Rhs element vgr protein
ASZ85_01396	COG1280	lysine exporter protein (LysE YggA)
ASZ85_01397	COG1115	amino acid carrier protein
ASZ85_01400	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASZ85_01401	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASZ85_01402	COG1177	transmembrane transport
ASZ85_01403	COG1176	ABC-type spermidine putrescine transport system, permease component I
ASZ85_01404	COG3842	ATPase activity
ASZ85_01408	COG0037	tRNA processing
ASZ85_01409	COG0589	response to stress
ASZ85_01410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASZ85_01413	COG2217	Heavy metal translocating P-type atpase
ASZ85_01415	COG2010	Cytochrome c
ASZ85_01418	COG3278	Belongs to the heme-copper respiratory oxidase family
ASZ85_01420	COG0784	Response regulator, receiver
ASZ85_01420	COG2205	protein histidine kinase activity
ASZ85_01425	COG2994	toxin metabolic process
ASZ85_01426	COG3064	Membrane
ASZ85_01426	COG1073	alpha beta
ASZ85_01426	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ASZ85_01452	COG3120	sequence-specific DNA binding
ASZ85_01453	COG1067	ATP-dependent peptidase activity
ASZ85_01454	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASZ85_01458	COG0116	Belongs to the methyltransferase superfamily
ASZ85_01458	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ASZ85_01461	COG0167	dihydroorotate dehydrogenase activity
ASZ85_01464	COG0308	aminopeptidase N
ASZ85_01467	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
ASZ85_01468	COG1956	GAF domain-containing protein
ASZ85_01469	COG1132	(ABC) transporter
ASZ85_01470	COG2995	paraquat-inducible protein a
ASZ85_01471	COG3008	intermembrane lipid transfer
ASZ85_01472	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ASZ85_01472	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ASZ85_01473	COG2996	Protein conserved in bacteria
ASZ85_01476	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASZ85_01478	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ASZ85_01481	COG0437	4 iron, 4 sulfur cluster binding
ASZ85_01482	COG0243	molybdopterin cofactor binding
ASZ85_01482	COG3383	formate dehydrogenase (NAD+) activity
ASZ85_01488	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ASZ85_01489	COG0488	(ABC) transporter
ASZ85_01490	COG3852	Histidine kinase
ASZ85_01491	COG2204	response regulator
ASZ85_01493	COG4662	Binding-protein-dependent transport system inner membrane component
ASZ85_01494	COG3842	ATPase activity
ASZ85_01495	COG0746	molybdenum cofactor guanylyltransferase activity
ASZ85_01501	COG1940	carbohydrate kinase activity
ASZ85_01504	COG0840	transmembrane signaling receptor activity
ASZ85_01505	COG0791	NLP P60 protein
ASZ85_01509	COG0534	Mate efflux family protein
ASZ85_01511	COG1793	dna ligase
ASZ85_01513	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ASZ85_01514	COG0848	biopolymer transport protein
ASZ85_01515	COG0811	peptide transport
ASZ85_01516	COG0811	peptide transport
ASZ85_01519	COG1175	transmembrane transport
ASZ85_01520	COG0395	ABC-type sugar transport system, permease component
ASZ85_01521	COG3842	ATPase activity
ASZ85_01522	COG1349	DNA-binding transcription factor activity
ASZ85_01523	COG0584	glycerophosphoryl diester phosphodiesterase
ASZ85_01524	COG2731	YhcH YjgK YiaL family protein
ASZ85_01525	COG0251	oxidation-reduction process
ASZ85_01527	COG1609	Transcriptional regulator
ASZ85_01528	COG2723	6-phospho-beta-galactosidase activity
ASZ85_01529	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ASZ85_01530	COG0583	DNA-binding transcription factor activity
ASZ85_01534	COG0577	efflux transmembrane transporter activity
ASZ85_01534	COG1136	(ABC) transporter
ASZ85_01535	COG1136	(ABC) transporter
ASZ85_01535	COG0577	efflux transmembrane transporter activity
ASZ85_01536	COG1136	(ABC) transporter
ASZ85_01536	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASZ85_01537	COG1294	oxidase, subunit
ASZ85_01538	COG1271	oxidase subunit
ASZ85_01546	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASZ85_01548	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASZ85_01552	COG0753	catalase activity
ASZ85_01555	COG3527	Alpha-acetolactate decarboxylase
ASZ85_01558	COG2200	EAL domain
ASZ85_01558	COG2199	diguanylate cyclase activity
ASZ85_01559	COG3706	GGDEF domain
ASZ85_01560	COG2017	converts alpha-aldose to the beta-anomer
ASZ85_01561	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ASZ85_01562	COG1085	galactose-1-phosphate uridylyltransferase
ASZ85_01567	COG0745	RESPONSE REGULATOR receiver
ASZ85_01567	COG3706	GGDEF domain
ASZ85_01570	COG0835	chemotaxis
ASZ85_01570	COG0784	Response regulator, receiver
ASZ85_01572	COG4565	transcriptional regulatory protein
ASZ85_01573	COG3290	protein histidine kinase activity
ASZ85_01575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ85_01579	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ASZ85_01580	COG3063	Type IV pilus biogenesis stability protein PilW
ASZ85_01583	COG1451	nucleotide metabolic process
ASZ85_01585	COG0583	DNA-binding transcription factor activity
ASZ85_01592	COG1538	Outer membrane efflux protein
ASZ85_01594	COG0019	diaminopimelate decarboxylase activity
ASZ85_01595	COG1748	Saccharopine dehydrogenase
ASZ85_01597	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASZ85_01600	COG4181	ATPase activity
ASZ85_01601	COG0534	Mate efflux family protein
ASZ85_01602	COG0702	epimerase
ASZ85_01604	COG2814	Major facilitator Superfamily
ASZ85_01605	COG1187	pseudouridine synthase activity
ASZ85_01606	COG1061	Type III restriction enzyme res subunit
ASZ85_01610	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ASZ85_01611	COG2203	Gaf domain
ASZ85_01611	COG4251	negative regulation of phosphorylation
ASZ85_01611	COG3706	GGDEF domain
ASZ85_01611	COG5001	Diguanylate cyclase
ASZ85_01613	COG0840	transmembrane signaling receptor activity
ASZ85_01619	COG4934	collagen metabolic process
ASZ85_01623	COG2239	Acts as a magnesium transporter
ASZ85_01626	COG0814	amino acid
ASZ85_01627	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ85_01628	COG1131	(ABC) transporter
ASZ85_01629	COG0842	Transport permease protein
ASZ85_01631	COG3313	Fe-S protein
ASZ85_01633	COG4134	Bacterial extracellular solute-binding protein
ASZ85_01634	COG4135	transport system, permease component
ASZ85_01635	COG4136	ATPase activity
ASZ85_01636	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASZ85_01637	COG0564	pseudouridine synthase activity
ASZ85_01639	COG0733	neurotransmitter:sodium symporter activity
ASZ85_01641	COG0626	cystathionine gamma-synthase activity
ASZ85_01642	COG2818	Glycosylase
ASZ85_01645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ85_01648	COG1842	Phage shock protein A
ASZ85_01649	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ASZ85_01651	COG4168	peptide transport system, permease
ASZ85_01652	COG4171	peptide transport system, permease
ASZ85_01654	COG4172	Belongs to the ABC transporter superfamily
ASZ85_01657	COG1227	inorganic diphosphatase activity
ASZ85_01662	COG0243	molybdopterin cofactor binding
ASZ85_01663	COG3005	denitrification pathway
ASZ85_01664	COG4459	periplasmic nitrate reductase
ASZ85_01665	COG2116	formate transmembrane transporter activity
ASZ85_01667	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASZ85_01668	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ASZ85_01670	COG2917	probably involved in intracellular septation
ASZ85_01671	COG1607	acyl-coa hydrolase
ASZ85_01672	COG2350	Protein conserved in bacteria
ASZ85_01674	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ASZ85_01675	COG0583	DNA-binding transcription factor activity
ASZ85_01678	COG0612	Peptidase, M16
ASZ85_01680	COG1032	radical SAM domain protein
ASZ85_01683	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ASZ85_01684	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ASZ85_01685	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
ASZ85_01686	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASZ85_01687	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ASZ85_01688	COG0745	RESPONSE REGULATOR receiver
ASZ85_01690	COG1609	Transcriptional regulator
ASZ85_01691	COG3070	regulator of competence-specific genes
ASZ85_01695	COG0297	glycogen (starch) synthase activity
ASZ85_01696	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ASZ85_01698	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASZ85_01700	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ASZ85_01702	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ASZ85_01703	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ASZ85_01704	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASZ85_01705	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASZ85_01711	COG1012	belongs to the aldehyde dehydrogenase family
ASZ85_01712	COG1309	transcriptional regulator
ASZ85_01716	COG0668	transmembrane transport
ASZ85_01717	COG2995	paraquat-inducible protein a
ASZ85_01718	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ASZ85_01718	COG3008	intermembrane lipid transfer
ASZ85_01720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ85_01723	COG0582	viral genome integration into host DNA
ASZ85_01724	COG0582	viral genome integration into host DNA
ASZ85_01725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASZ85_01729	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ASZ85_01733	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ASZ85_01737	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ASZ85_01738	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ASZ85_01739	COG1737	Transcriptional regulator
ASZ85_01740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASZ85_01741	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASZ85_01742	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASZ85_01743	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASZ85_01744	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ASZ85_01745	COG1940	carbohydrate kinase activity
ASZ85_01746	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ASZ85_01747	COG4409	exo-alpha-(2->6)-sialidase activity
ASZ85_01749	COG2003	Belongs to the UPF0758 family
ASZ85_01754	COG3941	tape measure
ASZ85_01760	COG0488	(ABC) transporter
ASZ85_01773	COG0415	Belongs to the DNA photolyase family
ASZ85_01775	COG4628	conserved protein (DUF2132)
ASZ85_01776	COG3284	Transcriptional regulator
ASZ85_01777	COG1012	belongs to the aldehyde dehydrogenase family
ASZ85_01779	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ85_01780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ85_01781	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ85_01783	COG2207	Transcriptional regulator
ASZ85_01784	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ85_01784	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ85_01784	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ85_01785	COG1482	cell wall glycoprotein biosynthetic process
ASZ85_01787	COG5002	protein histidine kinase activity
ASZ85_01787	COG0784	Response regulator, receiver
ASZ85_01789	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ASZ85_01791	COG2885	chlorophyll binding
ASZ85_01792	COG0823	Involved in the tonB-independent uptake of proteins
ASZ85_01795	COG0811	peptide transport
ASZ85_01796	COG0824	Thioesterase
ASZ85_01797	COG1294	oxidase, subunit
ASZ85_01798	COG1271	oxidase subunit
ASZ85_01799	COG2255	four-way junction helicase activity
ASZ85_01800	COG0632	four-way junction helicase activity
ASZ85_01801	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ASZ85_01802	COG0215	cysteine-tRNA ligase activity
ASZ85_01803	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ASZ85_01804	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASZ85_01805	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ASZ85_01807	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ASZ85_01808	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASZ85_01809	COG1199	ATP-dependent helicase activity
ASZ85_01810	COG0730	response to heat
ASZ85_01811	COG3923	Primosomal replication protein n
ASZ85_01813	COG0840	transmembrane signaling receptor activity
ASZ85_01814	COG0708	Exodeoxyribonuclease III
ASZ85_01815	COG4160	amino acid transport
ASZ85_01816	COG4215	(ABC) transporter
ASZ85_01821	COG1882	Formate acetyltransferase
ASZ85_01823	COG0840	transmembrane signaling receptor activity
ASZ85_01824	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ASZ85_01826	COG3013	Belongs to the UPF0304 family
ASZ85_01827	COG2766	serine protein kinase
ASZ85_01828	COG2718	Belongs to the UPF0229 family
ASZ85_01829	COG2719	SpoVR family
ASZ85_01830	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ASZ85_01832	COG1663	tetraacyldisaccharide 4'-kinase activity
ASZ85_01833	COG1132	(ABC) transporter
ASZ85_01834	COG0658	competence protein
ASZ85_01834	COG2333	competence protein COMEC
ASZ85_01836	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASZ85_01837	COG1136	(ABC) transporter
ASZ85_01838	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASZ85_01840	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ASZ85_01844	COG1252	NADH dehydrogenase
ASZ85_01850	COG0537	adenosine 5'-monophosphoramidase activity
ASZ85_01853	COG2186	Transcriptional regulator
ASZ85_01854	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASZ85_01855	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ASZ85_01856	COG1674	ftsk spoiiie
ASZ85_01858	COG0686	Belongs to the AlaDH PNT family
ASZ85_01860	COG0583	DNA-binding transcription factor activity
ASZ85_01864	COG0284	orotidine-5'-phosphate decarboxylase activity
ASZ85_01865	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ASZ85_01866	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ASZ85_01867	COG0776	regulation of translation
ASZ85_01868	COG0539	negative regulation of cytoplasmic translation
ASZ85_01869	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ASZ85_01870	COG1555	photosystem II stabilization
ASZ85_01871	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASZ85_01872	COG0776	regulation of translation
ASZ85_01873	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ASZ85_01874	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASZ85_01876	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASZ85_01877	COG4191	Histidine kinase
ASZ85_01879	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASZ85_01880	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASZ85_01881	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASZ85_01882	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ASZ85_01885	COG3300	MHYT domain
ASZ85_01885	COG5001	Diguanylate cyclase
ASZ85_01887	COG4589	Belongs to the CDS family
ASZ85_01894	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASZ85_01896	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASZ85_01900	COG0243	molybdopterin cofactor binding
ASZ85_01901	COG3005	denitrification pathway
ASZ85_01902	COG3325	Belongs to the glycosyl hydrolase 18 family
ASZ85_01902	COG3469	chitinase activity
ASZ85_01903	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASZ85_01905	COG2951	lytic endotransglycosylase activity
ASZ85_01906	COG3100	YcgL domain-containing protein
ASZ85_01907	COG0850	regulation of cytokinetic process
ASZ85_01908	COG2894	cell division
ASZ85_01909	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ASZ85_01910	COG3015	lipoprotein NlpE involved in copper resistance
ASZ85_01914	COG0477	Major facilitator Superfamily
ASZ85_01916	COG0840	transmembrane signaling receptor activity
ASZ85_01917	COG1396	sequence-specific DNA binding
ASZ85_01918	COG3135	benzoate transporter
ASZ85_01920	COG1441	menaquinone biosynthetic process
ASZ85_01922	COG0596	Alpha beta hydrolase
ASZ85_01923	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ASZ85_01924	COG1169	isochorismate synthase
ASZ85_01925	COG0436	Aminotransferase
ASZ85_01926	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ASZ85_01927	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ASZ85_01931	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ASZ85_01932	COG0318	PFAM AMP-dependent synthetase and ligase
ASZ85_01933	COG0596	Alpha beta hydrolase
ASZ85_01936	COG1214	PFAM Peptidase M22, glycoprotease
ASZ85_01937	COG1199	ATP-dependent helicase activity
ASZ85_01939	COG0788	formyltetrahydrofolate deformylase activity
ASZ85_01940	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASZ85_01940	COG1902	pentaerythritol trinitrate reductase activity
ASZ85_01941	COG0616	signal peptide processing
ASZ85_01942	COG0252	asparaginase activity
ASZ85_01943	COG3139	Protein of unknown function (DUF1315)
ASZ85_01946	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ85_01947	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASZ85_01948	COG0676	glucose-6-phosphate 1-epimerase activity
ASZ85_01950	COG2226	methyltransferase
ASZ85_01953	COG0835	chemotaxis
ASZ85_01953	COG0784	Response regulator, receiver
ASZ85_01954	COG1940	carbohydrate kinase activity
ASZ85_01956	COG4667	esterase of the alpha-beta hydrolase superfamily
ASZ85_01959	COG0733	neurotransmitter:sodium symporter activity
ASZ85_01960	COG1263	PTS System
ASZ85_01960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ85_01961	COG0084	hydrolase, TatD family'
ASZ85_01963	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASZ85_01964	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ASZ85_01965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASZ85_01966	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASZ85_01967	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASZ85_01968	COG1028	Short-chain dehydrogenase reductase Sdr
ASZ85_01969	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ASZ85_01970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASZ85_01971	COG0416	fatty acid biosynthetic process
ASZ85_01972	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ASZ85_01973	COG1399	metal-binding, possibly nucleic acid-binding protein
ASZ85_01974	COG0424	maF-like protein
ASZ85_01975	COG0564	pseudouridine synthase activity
ASZ85_01976	COG1530	ribonuclease E activity
ASZ85_01979	COG2842	Transposition protein
ASZ85_01997	COG3772	lysozyme
ASZ85_02030	COG0659	secondary active sulfate transmembrane transporter activity
ASZ85_02032	COG1454	alcohol dehydrogenase
ASZ85_02032	COG1012	belongs to the aldehyde dehydrogenase family
ASZ85_02033	COG2095	MarC family integral membrane protein
ASZ85_02034	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASZ85_02035	COG1757	Na H antiporter
ASZ85_02037	COG3081	Nucleoid-associated protein
ASZ85_02039	COG3083	sulfuric ester hydrolase activity
ASZ85_02042	COG0123	including yeast histone deacetylase and acetoin utilization protein
ASZ85_02043	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASZ85_02044	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ASZ85_02049	COG2853	Lipoprotein
ASZ85_02051	COG3088	subunit of a heme lyase
ASZ85_02051	COG4235	cytochrome complex assembly
ASZ85_02052	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASZ85_02053	COG1138	Cytochrome C-type biogenesis protein
ASZ85_02054	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ASZ85_02056	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASZ85_02057	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASZ85_02058	COG4133	protoheme IX ABC transporter activity
ASZ85_02060	COG0835	chemotaxis
ASZ85_02062	COG1192	Involved in chromosome partitioning
ASZ85_02063	COG2201	protein-glutamate methylesterase activity
ASZ85_02064	COG2198	Histidine kinase
ASZ85_02064	COG0643	Histidine kinase
ASZ85_02065	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ASZ85_02068	COG0455	bacterial-type flagellum organization
ASZ85_02071	COG2062	phosphohistidine phosphatase, SixA
ASZ85_02072	COG1025	Belongs to the peptidase M16 family
ASZ85_02074	COG0018	arginyl-trna synthetase
ASZ85_02078	COG1918	ferrous iron import across plasma membrane
ASZ85_02079	COG4977	sequence-specific DNA binding
ASZ85_02080	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ASZ85_02081	COG1121	(ABC) transporter
ASZ85_02082	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASZ85_02084	COG0045	succinate-CoA ligase (ADP-forming) activity
ASZ85_02085	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASZ85_02086	COG0567	Dehydrogenase, E1 component
ASZ85_02088	COG1053	succinate dehydrogenase
ASZ85_02089	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ASZ85_02090	COG2009	succinate dehydrogenase
ASZ85_02091	COG0372	Belongs to the citrate synthase family
ASZ85_02092	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ASZ85_02094	COG0033	Phosphoglucomutase
ASZ85_02095	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ASZ85_02096	COG0596	Alpha beta hydrolase
ASZ85_02099	COG1346	cytolysis
ASZ85_02101	COG0583	DNA-binding transcription factor activity
ASZ85_02103	COG0735	belongs to the Fur family
ASZ85_02104	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASZ85_02105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASZ85_02106	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASZ85_02107	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASZ85_02107	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ASZ85_02108	COG0431	NADPH-dependent FMN reductase
ASZ85_02110	COG3101	peptidyl-lysine hydroxylation
ASZ85_02111	COG2860	membrane
ASZ85_02112	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ASZ85_02113	COG2890	protein-(glutamine-N5) methyltransferase activity
ASZ85_02115	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ASZ85_02116	COG1684	flagellar biosynthetic protein fliR
ASZ85_02117	COG1987	bacterial-type flagellum assembly
ASZ85_02123	COG1580	Controls the rotational direction of flagella during chemotaxis
ASZ85_02128	COG1317	bacterial-type flagellum organization
ASZ85_02129	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASZ85_02131	COG1677	Flagellar hook-basal body complex protein FliE
ASZ85_02132	COG2204	response regulator
ASZ85_02133	COG4191	Histidine kinase
ASZ85_02134	COG2204	response regulator
ASZ85_02135	COG1516	flagellar protein fliS
ASZ85_02137	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ASZ85_02138	COG1334	flagellar protein FlaG
ASZ85_02139	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ85_02140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ85_02141	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ85_02142	COG2837	iron assimilation
ASZ85_02146	COG1393	Belongs to the ArsC family
ASZ85_02147	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASZ85_02148	COG1876	peptidase activity
ASZ85_02150	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ASZ85_02151	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASZ85_02153	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ASZ85_02157	COG4783	chaperone-mediated protein folding
ASZ85_02158	COG1393	Belongs to the ArsC family
ASZ85_02162	COG2233	PERMEase
ASZ85_02163	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ASZ85_02165	COG0737	Belongs to the 5'-nucleotidase family
ASZ85_02166	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ASZ85_02167	COG2912	Transglutaminase-like superfamily
ASZ85_02168	COG3094	Invasion gene expression up-regulator, SirB
ASZ85_02169	COG2890	protein-(glutamine-N5) methyltransferase activity
ASZ85_02170	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ASZ85_02171	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ASZ85_02172	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ASZ85_02173	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ASZ85_02174	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASZ85_02175	COG0193	aminoacyl-tRNA hydrolase activity
ASZ85_02176	COG0012	GTP binding
ASZ85_02194	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ85_02195	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ85_02199	COG1705	Flagellar rod assembly protein muramidase FlgJ
ASZ85_02199	COG3951	Flagellar rod assembly protein muramidase FlgJ
ASZ85_02200	COG1706	bacterial-type flagellum-dependent cell motility
ASZ85_02201	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ASZ85_02202	COG4786	Flagellar basal body rod
ASZ85_02203	COG4787	bacterial-type flagellum-dependent cell motility
ASZ85_02204	COG1749	Flagellar hook protein flgE
ASZ85_02205	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ASZ85_02206	COG1558	bacterial-type flagellum-dependent cell motility
ASZ85_02207	COG1815	bacterial-type flagellum-dependent cell motility
ASZ85_02208	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASZ85_02209	COG0784	Response regulator, receiver
ASZ85_02209	COG0835	chemotaxis
ASZ85_02216	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASZ85_02216	COG3433	isochorismatase activity
ASZ85_02216	COG2226	methyltransferase
ASZ85_02217	COG2375	cellular response to nickel ion
ASZ85_02218	COG4774	siderophore transport
ASZ85_02218	COG1629	transport
ASZ85_02221	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASZ85_02222	COG2217	Heavy metal translocating P-type atpase
ASZ85_02222	COG2608	mercury ion transmembrane transporter activity
ASZ85_02227	COG3735	TraB family
ASZ85_02230	COG2840	Smr protein MutS2
ASZ85_02231	COG1187	pseudouridine synthase activity
ASZ85_02232	COG3706	GGDEF domain
ASZ85_02233	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ASZ85_02234	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ASZ85_02235	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ASZ85_02236	COG0121	glutamine amidotransferase
ASZ85_02237	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ASZ85_02238	COG1960	acyl-CoA dehydrogenase activity
ASZ85_02240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASZ85_02241	COG0328	RNA-DNA hybrid ribonuclease activity
ASZ85_02242	COG2226	methyltransferase
ASZ85_02243	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASZ85_02244	COG1388	LysM domain
ASZ85_02244	COG0741	lytic transglycosylase activity
ASZ85_02246	COG0347	Belongs to the P(II) protein family
ASZ85_02247	COG3479	Phenolic acid decarboxylase
ASZ85_02249	COG0037	tRNA processing
ASZ85_02250	COG0825	malonyl-CoA metabolic process
ASZ85_02251	COG0587	DNA-directed DNA polymerase activity
ASZ85_02252	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ASZ85_02253	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASZ85_02254	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASZ85_02255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASZ85_02256	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASZ85_02257	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ASZ85_02259	COG0750	zinc metalloprotease
ASZ85_02260	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ASZ85_02261	COG0575	Belongs to the CDS family
ASZ85_02262	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASZ85_02263	COG0233	cytoplasmic translational termination
ASZ85_02264	COG0528	UMP kinase activity
ASZ85_02265	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ASZ85_02266	COG0052	Belongs to the universal ribosomal protein uS2 family
ASZ85_02267	COG0024	Methionine aminopeptidase
ASZ85_02268	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ASZ85_02270	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ASZ85_02271	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ASZ85_02272	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASZ85_02273	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ASZ85_02276	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASZ85_02276	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASZ85_02277	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASZ85_02278	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ASZ85_02279	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ASZ85_02282	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ASZ85_02283	COG2252	PERMEase
ASZ85_02284	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASZ85_02285	COG4067	protein conserved in archaea
ASZ85_02285	COG0189	ligase activity
ASZ85_02286	COG0189	ligase activity
ASZ85_02288	COG0733	neurotransmitter:sodium symporter activity
ASZ85_02289	COG3706	GGDEF domain
ASZ85_02291	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASZ85_02293	COG1477	protein flavinylation
ASZ85_02294	COG2871	sodium ion transport
ASZ85_02295	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASZ85_02296	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASZ85_02297	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASZ85_02298	COG1805	sodium ion transport
ASZ85_02299	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASZ85_02300	COG0271	Belongs to the BolA IbaG family
ASZ85_02301	COG2813	Specifically methylates the guanine in position
ASZ85_02303	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ASZ85_02304	COG2211	Major facilitator Superfamily
ASZ85_02306	COG1595	DNA-templated transcription, initiation
ASZ85_02308	COG3248	Nucleoside-binding outer membrane protein
ASZ85_02309	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ASZ85_02310	COG0693	protein deglycase activity
ASZ85_02311	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASZ85_02312	COG2166	iron-sulfur cluster assembly
ASZ85_02313	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ASZ85_02314	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ASZ85_02316	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASZ85_02316	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ASZ85_02318	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ASZ85_02319	COG1074	ATP-dependent DNA helicase activity
ASZ85_02320	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ASZ85_02323	COG3141	response to X-ray
ASZ85_02324	COG2171	N-acyltransferase activity
ASZ85_02326	COG0456	acetyltransferase
ASZ85_02327	COG0569	domain protein
ASZ85_02327	COG0189	ligase activity
ASZ85_02330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASZ85_02331	COG1609	Transcriptional regulator
ASZ85_02332	COG3250	beta-galactosidase activity
ASZ85_02335	COG1022	Amp-dependent synthetase and ligase
ASZ85_02336	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASZ85_02337	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ASZ85_02339	COG0560	Phosphoserine phosphatase
ASZ85_02341	COG0813	purine-nucleoside phosphorylase activity
ASZ85_02342	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ASZ85_02343	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ASZ85_02344	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ASZ85_02346	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASZ85_02347	COG0084	hydrolase, TatD family'
ASZ85_02350	COG1115	amino acid carrier protein
ASZ85_02353	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ASZ85_02354	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ASZ85_02355	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
ASZ85_02356	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ASZ85_02357	COG0083	homoserine kinase activity
ASZ85_02360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ASZ85_02362	COG0745	RESPONSE REGULATOR receiver
ASZ85_02363	COG0784	Response regulator, receiver
ASZ85_02363	COG2198	Histidine kinase
ASZ85_02363	COG5002	protein histidine kinase activity
ASZ85_02364	COG3706	GGDEF domain
ASZ85_02364	COG5001	Diguanylate cyclase
ASZ85_02364	COG4251	negative regulation of phosphorylation
ASZ85_02364	COG2203	Gaf domain
ASZ85_02365	COG1242	4 iron, 4 sulfur cluster binding
ASZ85_02367	COG0069	glutamate synthase activity
ASZ85_02367	COG0067	glutamate synthase
ASZ85_02367	COG0070	glutamate synthase
ASZ85_02369	COG0069	glutamate synthase activity
ASZ85_02369	COG0070	glutamate synthase
ASZ85_02369	COG0067	glutamate synthase
ASZ85_02370	COG0493	'glutamate synthase
ASZ85_02372	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ASZ85_02374	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASZ85_02375	COG2860	membrane
ASZ85_02376	COG0730	response to heat
ASZ85_02378	COG4172	Belongs to the ABC transporter superfamily
ASZ85_02381	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ASZ85_02382	COG0505	Belongs to the CarA family
ASZ85_02384	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ASZ85_02385	COG0494	nUDIX hydrolase
ASZ85_02386	COG0653	protein targeting
ASZ85_02388	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ASZ85_02389	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ASZ85_02390	COG0849	cell division
ASZ85_02391	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ASZ85_02392	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASZ85_02393	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ASZ85_02394	COG0772	Belongs to the SEDS family
ASZ85_02395	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ASZ85_02396	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASZ85_02397	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASZ85_02398	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ASZ85_02399	COG0768	penicillin binding
ASZ85_02400	COG3116	cell division
ASZ85_02401	COG0275	rRNA processing
ASZ85_02402	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASZ85_02403	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASZ85_02404	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ASZ85_02405	COG2186	Transcriptional regulator
ASZ85_02406	COG0737	Belongs to the 5'-nucleotidase family
ASZ85_02407	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASZ85_02408	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASZ85_02409	COG4974	Belongs to the 'phage' integrase family
ASZ85_02410	COG0716	FMN binding
ASZ85_02414	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASZ85_02415	COG1459	type II secretion system
ASZ85_02417	COG0237	dephospho-CoA kinase activity
ASZ85_02418	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ASZ85_02419	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ASZ85_02420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ASZ85_02421	COG0187	DNA topoisomerase II activity
ASZ85_02422	COG3150	esterase
ASZ85_02424	COG3151	Protein conserved in bacteria
ASZ85_02425	COG0494	nUDIX hydrolase
ASZ85_02426	COG1538	Outer membrane efflux protein
ASZ85_02428	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ASZ85_02429	COG0840	transmembrane signaling receptor activity
ASZ85_02430	COG3025	triphosphatase activity
ASZ85_02431	COG1392	Phosphate transport regulator
ASZ85_02432	COG0306	phosphate transporter
ASZ85_02433	COG4991	sh3 domain protein
ASZ85_02435	COG3267	Type II secretory pathway component ExeA
ASZ85_02435	COG3409	Peptidoglycan-binding domain 1 protein
ASZ85_02436	COG0617	tRNA 3'-terminal CCA addition
ASZ85_02437	COG0148	phosphopyruvate hydratase activity
ASZ85_02438	COG0504	CTP synthase activity
ASZ85_02440	COG3956	TIGRFAM MazG family protein
ASZ85_02441	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASZ85_02442	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASZ85_02444	COG5001	Diguanylate cyclase
ASZ85_02448	COG0736	holo-[acyl-carrier-protein] synthase activity
ASZ85_02449	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ASZ85_02450	COG1381	Involved in DNA repair and RecF pathway recombination
ASZ85_02451	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ASZ85_02452	COG0571	ribonuclease III activity
ASZ85_02453	COG0681	Belongs to the peptidase S26 family
ASZ85_02454	COG0481	GTPase activity
ASZ85_02455	COG3086	response to oxidative stress
ASZ85_02456	COG3026	antisigma factor binding
ASZ85_02458	COG1595	DNA-templated transcription, initiation
ASZ85_02459	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ASZ85_02461	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ASZ85_02462	COG0354	folic acid binding
ASZ85_02464	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASZ85_02465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASZ85_02467	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ASZ85_02468	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ASZ85_02469	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ASZ85_02470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASZ85_02471	COG0440	acetolactate synthase activity
ASZ85_02472	COG0028	Belongs to the TPP enzyme family
ASZ85_02473	COG1022	Amp-dependent synthetase and ligase
ASZ85_02474	COG0583	DNA-binding transcription factor activity
ASZ85_02478	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASZ85_02479	COG0473	3-isopropylmalate dehydrogenase activity
ASZ85_02480	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ASZ85_02481	COG0066	3-isopropylmalate dehydratase activity
ASZ85_02491	COG3437	response regulator, receiver
ASZ85_02494	COG0795	lipopolysaccharide-transporting ATPase activity
ASZ85_02495	COG0795	lipopolysaccharide-transporting ATPase activity
ASZ85_02496	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASZ85_02497	COG2927	DNA polymerase III (CHI subunit)
ASZ85_02498	COG0525	valine-tRNA ligase activity
ASZ85_02499	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASZ85_02500	COG0564	pseudouridine synthase activity
ASZ85_02501	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASZ85_02503	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ASZ85_02504	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ASZ85_02505	COG0540	Belongs to the ATCase OTCase family
ASZ85_02506	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
ASZ85_02508	COG0251	oxidation-reduction process
ASZ85_02509	COG0204	Acyl-transferase
ASZ85_02510	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ASZ85_02511	COG5007	Belongs to the BolA IbaG family
ASZ85_02513	COG2854	intermembrane phospholipid transfer
ASZ85_02514	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ASZ85_02515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASZ85_02516	COG1127	ABC transporter
ASZ85_02518	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ASZ85_02518	COG0517	IMP dehydrogenase activity
ASZ85_02521	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ASZ85_02522	COG1137	ATPase activity
ASZ85_02524	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ASZ85_02525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ85_02527	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ85_02528	COG2239	Acts as a magnesium transporter
ASZ85_02529	COG0312	modulator of DNA gyrase
ASZ85_02530	COG3028	Belongs to the UPF0307 family
ASZ85_02531	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ASZ85_02532	COG1178	ABC-type Fe3 transport system permease component
ASZ85_02533	COG4143	(ABC) transporter
ASZ85_02534	COG0163	prenyltransferase activity
ASZ85_02535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASZ85_02536	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ASZ85_02537	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ASZ85_02538	COG2105	PFAM AIG2 family protein
ASZ85_02540	COG0729	surface antigen
ASZ85_02541	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ85_02542	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ASZ85_02545	COG1136	(ABC) transporter
ASZ85_02549	COG0529	Catalyzes the synthesis of activated sulfate
ASZ85_02550	COG2895	sulfate adenylyltransferase (ATP) activity
ASZ85_02551	COG0175	sulfate reduction
ASZ85_02552	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ASZ85_02552	COG1648	precorrin-2 dehydrogenase activity
ASZ85_02553	COG0737	Belongs to the 5'-nucleotidase family
ASZ85_02555	COG0513	Belongs to the DEAD box helicase family
ASZ85_02556	COG2153	protein acetylation
ASZ85_02557	COG0697	spore germination
ASZ85_02559	COG0545	Peptidyl-prolyl cis-trans isomerase
ASZ85_02561	COG0203	ribosomal protein L17
ASZ85_02562	COG0202	RNA polymerase activity
ASZ85_02563	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ASZ85_02564	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ASZ85_02565	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ASZ85_02567	COG0201	protein transport
ASZ85_02568	COG0200	Binds to the 23S rRNA
ASZ85_02569	COG1841	ribosomal large subunit assembly
ASZ85_02570	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ASZ85_02571	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ASZ85_02572	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ASZ85_02573	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ASZ85_02574	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASZ85_02575	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ASZ85_02576	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ASZ85_02577	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ASZ85_02578	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ASZ85_02579	COG0255	Belongs to the universal ribosomal protein uL29 family
ASZ85_02580	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ASZ85_02581	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASZ85_02582	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ASZ85_02583	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ASZ85_02584	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ASZ85_02585	COG0089	rRNA binding
ASZ85_02586	COG0088	Forms part of the polypeptide exit tunnel
ASZ85_02587	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASZ85_02588	COG0051	transcription antitermination factor activity, RNA binding
ASZ85_02589	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASZ85_02590	COG0557	exoribonuclease II activity
ASZ85_02591	COG3083	sulfuric ester hydrolase activity
ASZ85_02592	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ASZ85_02593	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ASZ85_02595	COG1047	Peptidyl-prolyl cis-trans
ASZ85_02598	COG2249	NAD(P)H dehydrogenase (quinone) activity
ASZ85_02599	COG0488	(ABC) transporter
ASZ85_02601	COG0429	hydrolase of the alpha beta-hydrolase fold
ASZ85_02603	COG3954	Phosphoribulokinase
ASZ85_02604	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASZ85_02606	COG1012	belongs to the aldehyde dehydrogenase family
ASZ85_02608	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASZ85_02610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASZ85_02613	COG0180	Tryptophanyl-tRNA synthetase
ASZ85_02614	COG0546	phosphoglycolate phosphatase activity
ASZ85_02615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASZ85_02616	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ASZ85_02618	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ASZ85_02619	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ASZ85_02625	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ASZ85_02627	COG0678	peroxiredoxin activity
ASZ85_02627	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASZ85_02628	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASZ85_02630	COG0165	Argininosuccinate lyase
ASZ85_02631	COG0137	argininosuccinate synthase activity
ASZ85_02632	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASZ85_02633	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASZ85_02634	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASZ85_02635	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ASZ85_02638	COG1045	serine acetyltransferase
ASZ85_02639	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ASZ85_02640	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ASZ85_02641	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASZ85_02642	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ASZ85_02643	COG1053	succinate dehydrogenase
ASZ85_02644	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ASZ85_02645	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ASZ85_02646	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ASZ85_02647	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASZ85_02648	COG1509	lysine 2,3-aminomutase activity
ASZ85_02650	COG0459	protein refolding
ASZ85_02651	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ASZ85_02656	COG0149	triose-phosphate isomerase activity
ASZ85_02658	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ASZ85_02659	COG1575	Belongs to the MenA family. Type 1 subfamily
ASZ85_02660	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ASZ85_02661	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ASZ85_02662	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ASZ85_02664	COG1609	Transcriptional regulator
ASZ85_02665	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ASZ85_02666	COG0254	rRNA binding
ASZ85_02668	COG0281	malic enzyme
ASZ85_02669	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
ASZ85_02670	COG0626	cystathionine gamma-synthase activity
ASZ85_02671	COG0527	aspartate kinase activity
ASZ85_02671	COG0460	homoserine dehydrogenase
ASZ85_02672	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ASZ85_02674	COG1494	fructose-1,6-bisphosphatase
ASZ85_02675	COG0205	6-phosphofructokinase activity
ASZ85_02676	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ASZ85_02678	COG0745	RESPONSE REGULATOR receiver
ASZ85_02679	COG2205	protein histidine kinase activity
ASZ85_02681	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ASZ85_02682	COG3030	protein affecting phage T7 exclusion by the F plasmid
ASZ85_02683	COG3706	GGDEF domain
ASZ85_02684	COG1027	Aspartate ammonia-lyase
ASZ85_02685	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ASZ85_02686	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ASZ85_02690	COG4232	protein-disulfide reductase activity
ASZ85_02692	COG3263	regulation of cellular component size
ASZ85_02694	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASZ85_02695	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ASZ85_02696	COG0194	GDP metabolic process
ASZ85_02697	COG1758	RNA polymerase activity
ASZ85_02698	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASZ85_02699	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASZ85_02700	COG2233	PERMEase
ASZ85_02702	COG0745	RESPONSE REGULATOR receiver
ASZ85_02703	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASZ85_02704	COG2183	response to ionizing radiation
ASZ85_02706	COG0596	Alpha beta hydrolase
ASZ85_02708	COG1040	competence protein
ASZ85_02709	COG0316	Belongs to the HesB IscA family
ASZ85_02709	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ASZ85_02710	COG0494	nUDIX hydrolase
ASZ85_02711	COG1218	3'(2'),5'-bisphosphate nucleotidase
ASZ85_02713	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ASZ85_02714	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ASZ85_02715	COG3156	type II secretion system protein K
ASZ85_02716	COG4795	General secretion pathway protein
ASZ85_02717	COG2165	general secretion pathway protein
ASZ85_02718	COG2165	general secretion pathway protein
ASZ85_02719	COG2165	general secretion pathway protein
ASZ85_02720	COG1459	type II secretion system
ASZ85_02721	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASZ85_02723	COG3031	protein transport across the cell outer membrane
ASZ85_02724	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ASZ85_02725	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ASZ85_02726	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ASZ85_02728	COG0456	acetyltransferase
ASZ85_02729	COG1490	D-aminoacyl-tRNA deacylase activity
ASZ85_02734	COG0174	glutamine synthetase
ASZ85_02736	COG3852	Histidine kinase
ASZ85_02738	COG5001	Diguanylate cyclase
ASZ85_02738	COG3300	MHYT domain
ASZ85_02739	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ASZ85_02749	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ASZ85_02750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASZ85_02751	COG1739	Uncharacterized protein family UPF0029
ASZ85_02752	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASZ85_02752	COG1024	Enoyl-CoA hydratase
ASZ85_02753	COG0183	Belongs to the thiolase family
ASZ85_02754	COG0583	DNA-binding transcription factor activity
ASZ85_02755	COG2814	Major facilitator Superfamily
ASZ85_02756	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASZ85_02757	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ASZ85_02758	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ASZ85_02759	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ASZ85_02760	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ASZ85_02761	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASZ85_02762	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ASZ85_02764	COG0356	it plays a direct role in the translocation of protons across the membrane
ASZ85_02765	COG3312	ion transport
ASZ85_02766	COG1475	DNA binding
ASZ85_02767	COG1192	Involved in chromosome partitioning
ASZ85_02768	COG0357	Ribosomal RNA small subunit methyltransferase G
ASZ85_02769	COG0445	tRNA wobble uridine modification
ASZ85_02776	COG0217	transcriptional regulatory protein
ASZ85_02777	COG2084	Dehydrogenase
ASZ85_02780	COG2909	trisaccharide binding
ASZ85_02781	COG0058	SHG alpha-glucan phosphorylase activity
ASZ85_02782	COG1640	4-alpha-glucanotransferase
ASZ85_02783	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ASZ85_02785	COG3501	Rhs element vgr protein
ASZ85_02791	COG0471	metal ion transport
ASZ85_02792	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ASZ85_02800	COG0671	phosphoesterase, PA-phosphatase related
ASZ85_02801	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ASZ85_02803	COG1999	signal sequence binding
ASZ85_02807	COG0786	glutamate:sodium symporter activity
ASZ85_02811	COG1566	PFAM secretion protein HlyD family protein
ASZ85_02813	COG3706	GGDEF domain
ASZ85_02816	COG0813	purine-nucleoside phosphorylase activity
ASZ85_02818	COG3272	Protein of unknown function (DUF1722)
ASZ85_02820	COG0415	Belongs to the DNA photolyase family
ASZ85_02821	COG1376	ErfK ybiS ycfS ynhG family protein
ASZ85_02821	COG1388	LysM domain
ASZ85_02824	COG0513	Belongs to the DEAD box helicase family
ASZ85_02825	COG1770	oligopeptidase
ASZ85_02831	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASZ85_02832	COG0573	inorganic phosphate transmembrane transporter activity
ASZ85_02833	COG0581	inorganic phosphate transmembrane transporter activity
ASZ85_02834	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASZ85_02835	COG2199	diguanylate cyclase activity
ASZ85_02838	COG0659	secondary active sulfate transmembrane transporter activity
ASZ85_02840	COG0739	heme binding
ASZ85_02841	COG5001	Diguanylate cyclase
ASZ85_02841	COG3300	MHYT domain
ASZ85_02842	COG0583	DNA-binding transcription factor activity
ASZ85_02843	COG2814	Major facilitator Superfamily
ASZ85_02848	COG1301	dicarboxylic acid transport
ASZ85_02851	COG1342	Belongs to the UPF0251 family
ASZ85_02859	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ASZ85_02860	COG0673	inositol 2-dehydrogenase activity
ASZ85_02862	COG2200	EAL domain
ASZ85_02862	COG2771	luxR family
ASZ85_02863	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASZ85_02865	COG0564	pseudouridine synthase activity
ASZ85_02884	COG3501	Rhs element vgr protein
ASZ85_02888	COG1869	D-ribose catabolic process
ASZ85_02889	COG1129	ABC transporter
ASZ85_02890	COG1172	Belongs to the binding-protein-dependent transport system permease family
ASZ85_02891	COG1879	ABC-type sugar transport system periplasmic component
ASZ85_02892	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASZ85_02893	COG1609	Transcriptional regulator
ASZ85_02895	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ASZ85_02897	COG0584	glycerophosphoryl diester phosphodiesterase
ASZ85_02898	COG2271	Major facilitator Superfamily
ASZ85_02906	COG0579	oxidoreductase
ASZ85_02908	COG0242	peptide deformylase activity
ASZ85_02910	COG1320	monovalent cation:proton antiporter activity
ASZ85_02911	COG2212	antiporter activity
ASZ85_02915	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASZ85_02915	COG2111	Na H antiporter
ASZ85_02917	COG0589	response to stress
ASZ85_02918	COG0814	amino acid
ASZ85_02919	COG3033	Beta-eliminating lyase
ASZ85_02922	COG3530	Putative quorum-sensing-regulated virulence factor
ASZ85_02924	COG5002	protein histidine kinase activity
ASZ85_02924	COG5001	Diguanylate cyclase
ASZ85_02925	COG1278	Cold shock
ASZ85_02929	COG2304	oxidoreductase activity
ASZ85_02933	COG0714	Associated with various cellular activities
ASZ85_02934	COG0840	transmembrane signaling receptor activity
ASZ85_02938	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASZ85_02940	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASZ85_02942	COG3604	Transcriptional regulator
ASZ85_02943	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASZ85_02943	COG1017	nitric oxide dioxygenase activity
ASZ85_02944	COG1278	Cold shock
ASZ85_02945	COG3036	rescue of stalled ribosome
ASZ85_02951	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ASZ85_02951	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ASZ85_02952	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASZ85_02954	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASZ85_02957	COG0516	GMP reductase activity
ASZ85_02958	COG4974	Belongs to the 'phage' integrase family
ASZ85_02980	COG4695	Portal protein
ASZ85_03009	COG0516	GMP reductase activity
ASZ85_03014	COG1943	Transposase
ASZ85_03015	COG0513	Belongs to the DEAD box helicase family
ASZ85_03016	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ASZ85_03018	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ASZ85_03019	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ASZ85_03020	COG3437	response regulator, receiver
ASZ85_03020	COG0784	Response regulator, receiver
ASZ85_03021	COG4191	Histidine kinase
ASZ85_03021	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASZ85_03023	COG1757	Na H antiporter
ASZ85_03024	COG2814	Major facilitator Superfamily
ASZ85_03027	COG3706	GGDEF domain
ASZ85_03028	COG3240	lipase activity
ASZ85_03031	COG0840	transmembrane signaling receptor activity
ASZ85_03032	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ASZ85_03033	COG5380	lipid catabolic process
ASZ85_03034	COG3291	Pkd domain containing protein
ASZ85_03034	COG4412	M6 family metalloprotease domain protein
ASZ85_03040	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASZ85_03041	COG4605	iron ion homeostasis
ASZ85_03042	COG4604	ABC transporter, ATP-binding protein
ASZ85_03046	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASZ85_03050	COG0745	RESPONSE REGULATOR receiver
ASZ85_03052	COG3623	hexulose-6-phosphate isomerase
ASZ85_03053	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ASZ85_03054	COG0561	phosphatase activity
ASZ85_03060	COG3038	cytochrome b561
ASZ85_03061	COG0366	Alpha amylase catalytic
ASZ85_03067	COG0745	RESPONSE REGULATOR receiver
ASZ85_03068	COG5002	protein histidine kinase activity
ASZ85_03075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASZ85_03078	COG2814	Major facilitator Superfamily
ASZ85_03081	COG1686	Belongs to the peptidase S11 family
ASZ85_03087	COG1943	Transposase
ASZ85_03088	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASZ85_03088	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASZ85_03090	COG0509	glycine decarboxylation via glycine cleavage system
ASZ85_03091	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASZ85_03094	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ASZ85_03096	COG3039	Transposase
ASZ85_03101	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ASZ85_03103	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ASZ85_03104	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ASZ85_03121	COG1418	mRNA catabolic process
ASZ85_03139	COG1028	Short-chain dehydrogenase reductase Sdr
ASZ85_03140	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASZ85_03147	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ASZ85_03151	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASZ85_03152	COG0494	nUDIX hydrolase
ASZ85_03154	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ85_03156	COG3040	lipid binding
ASZ85_03162	COG3041	Addiction module toxin RelE StbE family
ASZ85_03169	COG1619	proteins homologs of microcin C7 resistance protein MccF
ASZ85_03172	COG3549	Plasmid maintenance system killer
ASZ85_03173	COG3093	addiction module antidote protein HigA
ASZ85_03200	COG1619	proteins homologs of microcin C7 resistance protein MccF
ASZ85_03202	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASZ85_03212	COG0346	lactoylglutathione lyase activity
ASZ85_03213	COG0384	phenazine biosynthesis protein PhzF
ASZ85_03216	COG3040	lipid binding
ASZ85_03220	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASZ85_03221	COG1280	lysine exporter protein (LysE YggA)
ASZ85_03226	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASZ85_03238	COG1619	proteins homologs of microcin C7 resistance protein MccF
ASZ85_03241	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASZ85_03249	COG3040	lipid binding
ASZ85_03250	COG3040	lipid binding
ASZ85_03261	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASZ85_03264	COG0384	phenazine biosynthesis protein PhzF
ASZ85_03265	COG3040	lipid binding
ASZ85_03274	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASZ85_03285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ85_03289	COG0384	phenazine biosynthesis protein PhzF
ASZ85_03298	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASZ85_03307	COG1619	proteins homologs of microcin C7 resistance protein MccF
ASZ85_03311	COG3040	lipid binding
ASZ85_03322	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ASZ85_03323	COG4977	sequence-specific DNA binding
ASZ85_03336	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ASZ85_03337	COG2944	sequence-specific DNA binding
ASZ85_03340	COG3039	Transposase
ASZ85_03341	COG0110	maltose O-acetyltransferase activity
ASZ85_03344	COG0346	lactoylglutathione lyase activity
ASZ85_03361	COG1943	Transposase
ASZ85_03372	COG0346	lactoylglutathione lyase activity
ASZ85_03377	COG1328	CTP reductase activity
ASZ85_03378	COG0602	queuosine metabolic process
ASZ85_03380	COG4067	protein conserved in archaea
ASZ85_03380	COG0189	ligase activity
ASZ85_03382	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ85_03382	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ASZ85_03382	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ85_03383	COG1105	Belongs to the carbohydrate kinase PfkB family
ASZ85_03384	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ85_03384	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ85_03385	COG1609	Transcriptional regulator
ASZ85_03386	COG0420	3'-5' exonuclease activity
ASZ85_03387	COG0419	ATPase involved in DNA repair
ASZ85_03388	COG0784	Response regulator, receiver
ASZ85_03388	COG2205	protein histidine kinase activity
ASZ85_03389	COG0156	8-amino-7-oxononanoate synthase activity
ASZ85_03391	COG0038	chloride channel
ASZ85_03392	COG0523	cobalamin synthesis protein
ASZ85_03394	COG3158	transport of potassium into the cell
ASZ85_03395	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ASZ85_03395	COG1013	pyruvate-flavodoxin oxidoreductase activity
ASZ85_03395	COG0674	pyruvate-flavodoxin oxidoreductase activity
ASZ85_03395	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASZ85_03396	COG2205	protein histidine kinase activity
ASZ85_03397	COG0745	RESPONSE REGULATOR receiver
ASZ85_03398	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASZ85_03399	COG0586	Pfam SNARE associated Golgi protein
ASZ85_03402	COG2200	EAL domain
ASZ85_03404	COG3038	cytochrome b561
ASZ85_03406	COG2116	formate transmembrane transporter activity
ASZ85_03407	COG0583	DNA-binding transcription factor activity
ASZ85_03409	COG3593	DNA synthesis involved in DNA repair
ASZ85_03410	COG0737	Belongs to the 5'-nucleotidase family
ASZ85_03414	COG2824	Alkylphosphonate utilization operon protein PhnA
ASZ85_03426	COG3706	GGDEF domain
ASZ85_03430	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ASZ85_03431	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ASZ85_03433	COG0745	RESPONSE REGULATOR receiver
ASZ85_03437	COG0023	Translation Initiation Factor
ASZ85_03439	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASZ85_03441	COG1042	CoA-binding domain protein
ASZ85_03441	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ85_03441	COG0045	succinate-CoA ligase (ADP-forming) activity
ASZ85_03442	COG0583	DNA-binding transcription factor activity
ASZ85_03443	COG1629	transport
ASZ85_03443	COG4771	TonB-dependent receptor
ASZ85_03447	COG2050	protein possibly involved in aromatic compounds catabolism
ASZ85_03452	COG0625	glutathione transferase activity
ASZ85_03455	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASZ85_03456	COG4172	Belongs to the ABC transporter superfamily
ASZ85_03457	COG4239	(ABC) transporter, permease
ASZ85_03458	COG4174	ABC transporter (Permease)
ASZ85_03459	COG4166	transmembrane transport
ASZ85_03468	COG3842	ATPase activity
ASZ85_03470	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ASZ85_03472	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASZ85_03473	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASZ85_03474	COG1011	Hydrolase
ASZ85_03476	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ASZ85_03479	COG1970	mechanosensitive ion channel activity
ASZ85_03481	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ASZ85_03482	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ85_03482	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ85_03483	COG0302	gtp cyclohydrolase
ASZ85_03485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ASZ85_03487	COG2897	thiosulfate sulfurtransferase activity
ASZ85_03488	COG2390	Transcriptional regulator
ASZ85_03489	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASZ85_03490	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASZ85_03496	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASZ85_03502	COG0583	DNA-binding transcription factor activity
ASZ85_03503	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ASZ85_03504	COG0778	Nitroreductase
ASZ85_03509	COG0640	Transcriptional regulator
ASZ85_03511	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASZ85_03520	COG1263	PTS System
ASZ85_03520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ85_03522	COG1621	beta-fructofuranosidase activity
ASZ85_03523	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASZ85_03524	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ASZ85_03526	COG2885	chlorophyll binding
ASZ85_03528	COG0545	Peptidyl-prolyl cis-trans isomerase
ASZ85_03529	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASZ85_03530	COG0840	transmembrane signaling receptor activity
ASZ85_03531	COG3069	C4-dicarboxylate transmembrane transporter activity
ASZ85_03532	COG1760	l-serine dehydratase
ASZ85_03537	COG1609	Transcriptional regulator
ASZ85_03538	COG2197	response regulator
ASZ85_03539	COG3850	Histidine kinase
ASZ85_03540	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASZ85_03542	COG0243	molybdopterin cofactor binding
ASZ85_03546	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ASZ85_03547	COG2197	response regulator
ASZ85_03548	COG3851	Histidine kinase
ASZ85_03549	COG2271	Major facilitator Superfamily
ASZ85_03550	COG1840	ABC-type Fe3 transport system, periplasmic component
ASZ85_03552	COG3842	ATPase activity
ASZ85_03553	COG3243	poly(R)-hydroxyalkanoic acid synthase
ASZ85_03555	COG0183	Belongs to the thiolase family
ASZ85_03557	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASZ85_03558	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASZ85_03561	COG3706	GGDEF domain
ASZ85_03562	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ASZ85_03565	COG1979	alcohol dehydrogenase
ASZ85_03568	COG4191	Histidine kinase
ASZ85_03569	COG1840	ABC-type Fe3 transport system, periplasmic component
ASZ85_03571	COG2271	Major facilitator Superfamily
ASZ85_03572	COG0469	pyruvate kinase activity
ASZ85_03573	COG0784	Response regulator, receiver
ASZ85_03573	COG2198	Histidine kinase
ASZ85_03573	COG2205	protein histidine kinase activity
ASZ85_03574	COG1879	ABC-type sugar transport system periplasmic component
ASZ85_03575	COG1803	Methylglyoxal synthase
ASZ85_03576	COG1335	isochorismatase
ASZ85_03578	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ASZ85_03581	COG0210	DNA helicase
ASZ85_03582	COG1289	transmembrane transporter activity
ASZ85_03588	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ASZ85_03589	COG4149	molybdate abc transporter
ASZ85_03590	COG0725	ABC transporter, periplasmic molybdate-binding protein
ASZ85_03591	COG1492	cobalamin metabolic process
ASZ85_03601	COG5002	protein histidine kinase activity
ASZ85_03601	COG0784	Response regulator, receiver
ASZ85_03602	COG1879	ABC-type sugar transport system periplasmic component
ASZ85_03604	COG2827	Endonuclease containing a URI domain
ASZ85_03612	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ASZ85_03615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ASZ85_03616	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
ASZ85_03617	COG0247	lactate metabolic process
ASZ85_03618	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASZ85_03619	COG3118	belongs to the thioredoxin family
ASZ85_03627	COG0583	DNA-binding transcription factor activity
ASZ85_03628	COG4160	amino acid transport
ASZ85_03629	COG4215	(ABC) transporter
ASZ85_03630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASZ85_03631	COG1126	abc transporter atp-binding protein
ASZ85_03633	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ASZ85_03635	COG0494	nUDIX hydrolase
ASZ85_03636	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ASZ85_03638	COG1309	transcriptional regulator
ASZ85_03639	COG0513	Belongs to the DEAD box helicase family
ASZ85_03640	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
ASZ85_03642	COG0814	amino acid
ASZ85_03643	COG0840	transmembrane signaling receptor activity
ASZ85_03644	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ASZ85_03646	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ASZ85_03648	COG1984	allophanate hydrolase subunit 2
ASZ85_03652	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ASZ85_03653	COG4181	ATPase activity
ASZ85_03655	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASZ85_03656	COG5001	Diguanylate cyclase
ASZ85_03656	COG1716	ATPase activity
ASZ85_03658	COG0484	heat shock protein binding
ASZ85_03667	COG0546	phosphoglycolate phosphatase activity
ASZ85_03670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASZ85_03671	COG1368	sulfuric ester hydrolase activity
ASZ85_03673	COG0513	Belongs to the DEAD box helicase family
ASZ85_03674	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
ASZ85_03676	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASZ85_03678	COG3046	protein related to deoxyribodipyrimidine photolyase
ASZ85_03679	COG3397	chitin binding
ASZ85_03680	COG3227	Zinc metalloprotease (Elastase)
ASZ85_03682	COG0010	Belongs to the arginase family
ASZ85_03683	COG1166	arginine decarboxylase activity
ASZ85_03686	COG2239	Acts as a magnesium transporter
ASZ85_03687	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ASZ85_03688	COG0459	protein refolding
ASZ85_03690	COG0527	aspartate kinase activity
ASZ85_03691	COG0662	Cupin 2, conserved barrel domain protein
ASZ85_03692	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ASZ85_03693	COG0456	acetyltransferase
ASZ85_03695	COG2154	pterin-4-alpha-carbinolamine dehydratase
ASZ85_03696	COG3186	Phenylalanine-4-hydroxylase
ASZ85_03697	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASZ85_03700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASZ85_03701	COG0583	DNA-binding transcription factor activity
ASZ85_03704	COG2171	N-acyltransferase activity
ASZ85_03705	COG1253	flavin adenine dinucleotide binding
ASZ85_03706	COG1765	OsmC-like protein
ASZ85_03714	COG0531	amino acid
ASZ85_03715	COG3706	GGDEF domain
ASZ85_03717	COG3279	Response regulator of the LytR AlgR family
ASZ85_03718	COG3275	phosphorelay sensor kinase activity
ASZ85_03721	COG0577	efflux transmembrane transporter activity
ASZ85_03721	COG1136	(ABC) transporter
ASZ85_03722	COG1136	(ABC) transporter
ASZ85_03726	COG4989	oxidoreductase activity
ASZ85_03727	COG0366	Alpha amylase catalytic
ASZ85_03730	COG2067	long-chain fatty acid transport protein
ASZ85_03731	COG2267	carboxylic ester hydrolase activity
ASZ85_03733	COG3227	Zinc metalloprotease (Elastase)
ASZ85_03734	COG3047	cAMP biosynthetic process
ASZ85_03736	COG1686	Belongs to the peptidase S11 family
ASZ85_03737	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASZ85_03739	COG1271	oxidase subunit
ASZ85_03740	COG1294	oxidase, subunit
ASZ85_03742	COG3048	D-serine ammonia-lyase activity
ASZ85_03743	COG0583	DNA-binding transcription factor activity
ASZ85_03751	COG1063	alcohol dehydrogenase
ASZ85_03758	COG3157	Type VI secretion system effector, Hcp
ASZ85_03783	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASZ85_03784	COG0569	domain protein
ASZ85_03785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASZ85_03786	COG0745	RESPONSE REGULATOR receiver
ASZ85_03787	COG2205	protein histidine kinase activity
ASZ85_03790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASZ85_03791	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ASZ85_03796	COG1802	Transcriptional regulator
ASZ85_03796	COG4626	Terminase
ASZ85_03803	COG0582	viral genome integration into host DNA
ASZ85_03808	COG1063	alcohol dehydrogenase
ASZ85_03810	COG0693	protein deglycase activity
ASZ85_03813	COG0346	lactoylglutathione lyase activity
ASZ85_03818	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ASZ85_03819	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ASZ85_03820	COG0363	glucosamine-6-phosphate deaminase activity
ASZ85_03821	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ASZ85_03826	COG1929	Belongs to the glycerate kinase type-1 family
ASZ85_03827	COG2610	gluconate transmembrane transporter activity
ASZ85_03828	COG3835	regulator
ASZ85_03830	COG0748	coenzyme F420 binding
ASZ85_03831	COG3721	Heme iron utilization protein
ASZ85_03833	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ASZ85_03834	COG0811	peptide transport
ASZ85_03835	COG0848	biopolymer transport protein
ASZ85_03836	COG4558	Periplasmic binding protein
ASZ85_03837	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASZ85_03838	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ASZ85_03845	COG3217	Mosc domain protein beta barrel domain protein
ASZ85_03845	COG3217	Mosc domain protein beta barrel domain protein
ASZ85_03845	COG0633	Ferredoxin
ASZ85_03845	COG0633	Ferredoxin
ASZ85_03846	COG0418	dihydroorotase activity
ASZ85_03848	COG3152	Membrane
ASZ85_03850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASZ85_03851	COG2354	Protein conserved in bacteria
ASZ85_03852	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ASZ85_03853	COG1278	Cold shock
ASZ85_03858	COG3706	GGDEF domain
ASZ85_03859	COG1349	DNA-binding transcription factor activity
ASZ85_03862	COG3833	ABC-type maltose transport systems, permease component
ASZ85_03863	COG1175	transmembrane transport
ASZ85_03865	COG3842	ATPase activity
ASZ85_03866	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ85_03873	COG0583	DNA-binding transcription factor activity
ASZ85_03874	COG5001	Diguanylate cyclase
ASZ85_03876	COG1741	Belongs to the pirin family
ASZ85_03877	COG3123	guanosine phosphorylase activity
ASZ85_03879	COG2211	Major facilitator Superfamily
ASZ85_03881	COG0840	transmembrane signaling receptor activity
ASZ85_03883	COG1067	ATP-dependent peptidase activity
ASZ85_03885	COG4172	Belongs to the ABC transporter superfamily
ASZ85_03889	COG0583	DNA-binding transcription factor activity
ASZ85_03891	COG1620	l-lactate permease
ASZ85_03892	COG1304	FMN binding
ASZ85_03894	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ASZ85_03896	COG0840	transmembrane signaling receptor activity
ASZ85_03898	COG0513	Belongs to the DEAD box helicase family
ASZ85_03900	COG0583	DNA-binding transcription factor activity
ASZ85_03902	COG1902	pentaerythritol trinitrate reductase activity
ASZ85_03904	COG1132	(ABC) transporter
ASZ85_03906	COG1902	pentaerythritol trinitrate reductase activity
ASZ85_03908	COG1280	lysine exporter protein (LysE YggA)
ASZ85_03909	COG2207	Transcriptional regulator
ASZ85_03913	COG1846	Transcriptional regulator
ASZ85_03914	COG1764	response to oxidative stress
ASZ85_03915	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASZ85_03917	COG0697	spore germination
ASZ85_03919	COG0700	Nucleoside recognition
ASZ85_03920	COG3366	ferrous iron transmembrane transporter activity
ASZ85_03921	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ASZ85_03923	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASZ85_03924	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ASZ85_03925	COG2259	Doxx family
ASZ85_03930	COG0363	glucosamine-6-phosphate deaminase activity
ASZ85_03933	COG4580	involved in the transport of maltose and maltodextrins
ASZ85_03936	COG0840	transmembrane signaling receptor activity
ASZ85_03939	COG0840	transmembrane signaling receptor activity
ASZ85_03941	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASZ85_03942	COG1126	abc transporter atp-binding protein
ASZ85_03944	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASZ85_03945	COG4597	amino acid ABC transporter
ASZ85_03946	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASZ85_03948	COG0739	heme binding
ASZ85_03950	COG2213	PTS system mannitol-specific
ASZ85_03950	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ85_03951	COG0246	Mannitol dehydrogenase
ASZ85_03952	COG3722	fumarate hydratase activity
ASZ85_03953	COG0673	inositol 2-dehydrogenase activity
ASZ85_03959	COG2910	NAD(P)H-binding
ASZ85_03961	COG0840	transmembrane signaling receptor activity
ASZ85_03962	COG4221	oxidoreductase activity
ASZ85_03964	COG1901	pseudouridine methyltransferase
ASZ85_03965	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASZ85_03967	COG0531	amino acid
ASZ85_03968	COG1982	Orn Lys Arg decarboxylase major
ASZ85_03976	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASZ85_03982	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ASZ85_03984	COG0259	pyridoxamine-phosphate oxidase activity
ASZ85_03990	COG0745	RESPONSE REGULATOR receiver
ASZ85_03994	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ASZ85_03995	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASZ85_03996	COG0840	transmembrane signaling receptor activity
ASZ85_03997	COG0835	chemotaxis
ASZ85_03998	COG0835	chemotaxis
ASZ85_03999	COG0643	Histidine kinase
ASZ85_03999	COG2198	Histidine kinase
ASZ85_04003	COG0601	transmembrane transport
ASZ85_04004	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASZ85_04006	COG2194	sulfuric ester hydrolase activity
ASZ85_04007	COG0642	Histidine kinase
ASZ85_04008	COG0745	RESPONSE REGULATOR receiver
ASZ85_04014	COG1444	tRNA N-acetyltransferase activity
ASZ85_04015	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine