locus-tag	class	description
GTF75_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GTF75_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GTF75_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GTF75_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GTF75_00030	ENOG4108ZNX	Heat shock protein
GTF75_00035	ENOG4105JKW	Valine--pyruvate aminotransferase
GTF75_00040	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GTF75_00045	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
GTF75_00060	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GTF75_00070	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
GTF75_00075	ENOG4105C7B	Threonine dehydratase
GTF75_00080	ENOG4105C01	Dihydroxy-acid dehydratase
GTF75_00085	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GTF75_00100	ENOG4105C0P	Mg chelatase subunit ChlI
GTF75_00105	ENOG4106HNH	Acyl-transferase
GTF75_00110	ENOG4108Z33	Thiol disulfide Interchange Protein
GTF75_00115	ENOG4105E27	serine threonine protein kinase
GTF75_00125	ENOG4105PC1	Conserved Protein
GTF75_00130	ENOG4108N23	SpoOM-related protein
GTF75_00135	ENOG4108UT2	hemolysin iii
GTF75_00145	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GTF75_00150	ENOG4105C1A	potassium transporter peripheral membrane
GTF75_00155	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GTF75_00160	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GTF75_00170	ENOG4108WZM	domain protein
GTF75_00175	ENOG4105C79	DNA protecting protein DprA
GTF75_00180	ENOG4108RPN	Protein smg homolog
GTF75_00185	ENOG4108WI1	Dna topoisomerase
GTF75_00190	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GTF75_00195	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GTF75_00200	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GTF75_00205	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GTF75_00210	ENOG4105E2X	shikimate dehydrogenase
GTF75_00220	ENOG4108Z0R	Transferase
GTF75_00260	ENOG4105WMR	Protein CrcB homolog
GTF75_00265	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
GTF75_00275	ENOG4105D06	uba thif-type nad fad binding protein
GTF75_00280	ENOG4105WHD	thiamine biosynthesis protein ThiS
GTF75_00285	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GTF75_00290	ENOG4105D41	biosynthesis protein thiH
GTF75_00295	ENOG4105DC7	peptidase M24
GTF75_00295	ENOG4105DC7	peptidase M24
GTF75_00300	ENOG4105G2Y	Transcriptional regulator
GTF75_00305	ENOG4105CNH	Multidrug resistance protein MdtL
GTF75_00315	ENOG4108VVK	transcriptional Regulator, AsnC
GTF75_00320	ENOG4105BZU	Histidine kinase
GTF75_00335	ENOG4105EMK	carboxylate amino acid amine transporter
GTF75_00340	ENOG4108M6U	Universal stress protein A
GTF75_00345	ENOG41090A1	ferritin
GTF75_00350	ENOG4108V6B	universal stress protein B
GTF75_00355	ENOG4105CBX	hi0933 family
GTF75_00365	ENOG4105CGY	Dna recombination protein
GTF75_00370	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GTF75_00375	ENOG4105JC1	sterol-binding domain protein
GTF75_00385	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GTF75_00390	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
GTF75_00395	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GTF75_00400	ENOG4105CA0	peroxidase
GTF75_00405	ENOG4107R73	Mate efflux family protein
GTF75_00415	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GTF75_00425	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GTF75_00430	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
GTF75_00435	ENOG4105X6C	Flagellar basal body-associated protein FliL
GTF75_00440	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_00450	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GTF75_00455	ENOG4105F8V	Hydrolase, tatD family
GTF75_00460	ENOG4105D52	delta-aminolevulinic acid dehydratase
GTF75_00470	ENOG4105C2M	dna polymerase I
GTF75_00480	ENOG4106RE7	Cytochrome
GTF75_00490	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
GTF75_00495	ENOG4105XCT	Protein of unknown function (DUF2489)
GTF75_00500	ENOG4105D4P	Coproporphyrinogen iii oxidase
GTF75_00505	ENOG410601J	HemY protein
GTF75_00510	ENOG4105ECF	c-methyltransferase
GTF75_00515	ENOG41076E6	Uroporphyrinogen-III Synthase
GTF75_00520	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GTF75_00525	ENOG4107T0K	Adenylate cyclase
GTF75_00530	ENOG4105XQ6	frataxin-like protein
GTF75_00540	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GTF75_00545	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GTF75_00550	ENOG4105CT0	Protein of unknown function, DUF484
GTF75_00555	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GTF75_00560	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
GTF75_00565	ENOG4105BZU	Histidine kinase
GTF75_00580	ENOG4105DQF	Hydrolase
GTF75_00585	ENOG4108EUD	Lysophospholipase
GTF75_00590	ENOG410829K	Lysine exporter protein (Lyse ygga)
GTF75_00595	ENOG4105D58	Diguanylate phosphodiesterase
GTF75_00600	ENOG4108RMU	ferritin dps family protein
GTF75_00630	ENOG4106H78	methyltransferase
GTF75_00635	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GTF75_00640	ENOG4105CAK	Cell division ATP-binding protein ftsE
GTF75_00645	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GTF75_00650	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GTF75_00655	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
GTF75_00670	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
GTF75_00675	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GTF75_00680	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
GTF75_00685	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GTF75_00735	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GTF75_00740	ENOG4105BZU	Histidine kinase
GTF75_00745	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GTF75_00750	ENOG4105CUX	Signal transduction histidine kinase
GTF75_00760	ENOG4105C5F	glutamine synthetase
GTF75_00770	ENOG4105CI3	gtp-binding protein typa
GTF75_00780	ENOG4107S2Z	UPF0761 membrane protein
GTF75_00785	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GTF75_00790	ENOG4105SUU	thioesterase domain
GTF75_00800	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GTF75_00805	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GTF75_00810	ENOG4105VEJ	Heat shock protein
GTF75_00815	ENOG4108XKW	General secretion pathway protein C
GTF75_00825	ENOG4107QHF	type ii secretion system protein e
GTF75_00830	ENOG4105D7Q	type ii secretion system
GTF75_00835	ENOG4108VAU	general secretion pathway protein G
GTF75_00840	ENOG4105VWV	general secretion pathway protein h
GTF75_00845	ENOG4105X5Z	General secretion pathway protein I
GTF75_00850	ENOG4108WWZ	General secretion pathway protein J
GTF75_00855	ENOG4108RTD	type II secretion system protein K
GTF75_00860	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
GTF75_00865	ENOG4105U1E	general secretion pathway protein M
GTF75_00870	ENOG4105PIC	general secretion pathway protein N
GTF75_00875	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GTF75_00880	ENOG4107RK2	ADP-ribose diphosphatase NudE
GTF75_00890	ENOG4105MJ2	Competence protein
GTF75_00900	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GTF75_00910	ENOG4105BZM	domain protein
GTF75_00915	ENOG4108RRZ	Transcription elongation factor GreB
GTF75_00925	ENOG4105E0F	Histidine kinase
GTF75_00930	ENOG4105C2W	permease
GTF75_00935	ENOG4105CB5	ATP-dependent DNA helicase recG
GTF75_00940	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GTF75_00945	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GTF75_00950	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GTF75_00955	ENOG4105EX9	Membrane
GTF75_00960	ENOG4107QN1	sodium solute
GTF75_00980	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GTF75_00990	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GTF75_00995	ENOG4108IJ0	Aspartate ammonia-lyase
GTF75_01000	ENOG4105BZU	Histidine kinase
GTF75_01005	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
GTF75_01010	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GTF75_01020	ENOG4105E0F	Histidine kinase
GTF75_01025	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GTF75_01035	ENOG41076HS	cation diffusion facilitator family transporter
GTF75_01040	ENOG4105CTQ	phosphohexokinase
GTF75_01045	ENOG4105CBT	Fructose-1,6-bisphosphatase
GTF75_01050	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
GTF75_01055	ENOG4105SYT	Methylenetetrahydrofolate reductase
GTF75_01060	ENOG4105CFH	Aspartokinase
GTF75_01065	ENOG4105C28	cystathionine
GTF75_01070	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
GTF75_01075	ENOG4105C6K	Malic enzyme
GTF75_01080	ENOG4105VFB	Binds the 23S rRNA (By similarity)
GTF75_01085	ENOG4105C25	Primosomal protein n'
GTF75_01090	ENOG4105ETE	Transcriptional regulator (LacI family
GTF75_01095	ENOG41063M6	Cell Division Protein
GTF75_01100	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GTF75_01105	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GTF75_01110	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GTF75_01115	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GTF75_01125	ENOG4105CP7	Triose-phosphate isomerase
GTF75_01150	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GTF75_01155	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GTF75_01165	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
GTF75_01170	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GTF75_01180	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GTF75_01185	ENOG4105E33	succinate dehydrogenase
GTF75_01195	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
GTF75_01200	ENOG4107YZP	Rhodanese domain protein
GTF75_01205	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GTF75_01210	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GTF75_01215	ENOG4105D7W	serine acetyltransferase
GTF75_01225	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
GTF75_01230	ENOG4105CWC	Acetylornithine deacetylase
GTF75_01235	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GTF75_01240	ENOG4105CAS	nag kinase
GTF75_01245	ENOG4105CDH	Citrulline--aspartate ligase
GTF75_01250	ENOG4105CH7	arginosuccinase
GTF75_01260	ENOG4107QN2	dihydrolipoyl dehydrogenase
GTF75_01265	ENOG4105EHV	domain protein
GTF75_01275	ENOG4108JQC	penicillin-binding protein 1A
GTF75_01300	ENOG4105E4G	Type IV pilus
GTF75_01305	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GTF75_01310	ENOG4105D49	3-dehydroquinate synthase
GTF75_01320	ENOG4105DFE	Dna adenine methylase
GTF75_01325	ENOG4105DJV	ribulose-phosphate 3-epimerase
GTF75_01330	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GTF75_01335	ENOG4105C31	Tryptophanyl-tRNA synthetase
GTF75_01350	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
GTF75_01355	ENOG4105DDQ	anthranilate synthase
GTF75_01360	ENOG4105C8Y	Acetylornithine aminotransferase
GTF75_01370	ENOG4105C26	Dehydrogenase
GTF75_01380	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
GTF75_01385	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
GTF75_01395	ENOG4105DNZ	Alpha Beta Hydrolase
GTF75_01405	ENOG4105C5H	ABC transporter
GTF75_01410	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GTF75_01425	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GTF75_01430	ENOG4105D44	asparaginase
GTF75_01440	ENOG4108UV7	flagellar protein motX
GTF75_01445	ENOG4105E68	Sulfatase
GTF75_01450	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GTF75_01455	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GTF75_01460	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GTF75_01465	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GTF75_01470	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GTF75_01475	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GTF75_01480	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GTF75_01485	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GTF75_01490	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GTF75_01495	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GTF75_01500	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GTF75_01505	ENOG41083MP	50s ribosomal protein l29
GTF75_01510	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GTF75_01515	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GTF75_01520	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GTF75_01525	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GTF75_01530	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GTF75_01535	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GTF75_01545	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GTF75_01550	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GTF75_01555	ENOG4105VPB	50S ribosomal protein L30
GTF75_01565	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GTF75_01575	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GTF75_01580	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GTF75_01585	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GTF75_01590	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GTF75_01595	ENOG4108ZT0	50S ribosomal protein l17
GTF75_01605	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GTF75_01610	ENOG4108UBT	opacity-associated protein
GTF75_01615	ENOG4108SXK	Transporter Drug Metabolite Exporter family
GTF75_01620	ENOG4107YB6	acetyltransferase, (GNAT) family
GTF75_01625	ENOG4105C1J	atp-dependent rna helicase
GTF75_01635	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
GTF75_01640	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GTF75_01655	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
GTF75_01675	ENOG4105C19	ABC transporter
GTF75_01690	ENOG4108UUE	Transcriptional regulator
GTF75_01695	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GTF75_01700	ENOG4105CFU	surface antigen
GTF75_01710	ENOG41066HZ	AIG2-like family
GTF75_01715	ENOG4105F0N	pyrophosphate phospho-hydrolase
GTF75_01725	ENOG4105DFU	Cell wall formation (By similarity)
GTF75_01730	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GTF75_01740	ENOG4106SMU	thiamine transporter membrane protein
GTF75_01745	ENOG4107T0D	ABC, transporter
GTF75_01750	ENOG4105N42	UPF0307 protein
GTF75_01755	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
GTF75_01760	ENOG4105CJW	magnesium transporter
GTF75_01765	ENOG41080Z8	PHOSPHOCARRIER protein
GTF75_01770	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GTF75_01775	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
GTF75_01780	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
GTF75_01785	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GTF75_01790	ENOG4108IUZ	ABC transporter
GTF75_01795	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
GTF75_01805	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
GTF75_01810	ENOG4105C2X	Arabinose 5-phosphate isomerase
GTF75_01820	ENOG4105DHJ	ABC, transporter
GTF75_01825	ENOG4105CY3	ABC transporter, permease
GTF75_01830	ENOG4107PE3	Mammalian cell entry related domain protein
GTF75_01835	ENOG4105E3I	toluene tolerance
GTF75_01845	ENOG4105VFK	BolA family
GTF75_01850	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GTF75_01855	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
GTF75_01860	ENOG4105KME	endoribonuclease L-psp
GTF75_01870	ENOG4105CXT	aspartate transcarbamylase
GTF75_01880	ENOG4108IAB	Phoh family
GTF75_01890	ENOG4105D3G	Pseudouridine synthase
GTF75_01895	ENOG4105C5I	Dehydrogenase
GTF75_01900	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GTF75_01905	ENOG4105MYG	DNA polymerase iii, chi subunit
GTF75_01910	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GTF75_01915	ENOG4108M8S	permease YjgP YjgQ family protein
GTF75_01920	ENOG4108K5H	permease YjgP YjgQ family protein
GTF75_01935	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GTF75_01980	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GTF75_01985	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GTF75_01990	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GTF75_02015	ENOG41064T2	transcriptional regulator, lysR family
GTF75_02020	ENOG4108IQE	Amp-dependent synthetase and ligase
GTF75_02025	ENOG4105C7K	acetolactate synthase
GTF75_02030	ENOG4108ZP8	Acetolactate synthase small subunit
GTF75_02035	ENOG4108JQ1	Dehydrogenase
GTF75_02040	ENOG4105E66	phosphoriboisomerase A
GTF75_02045	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GTF75_02055	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
GTF75_02065	ENOG4105D0A	hydroxylase
GTF75_02070	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GTF75_02085	ENOG4105Y75	tpr repeat protein
GTF75_02095	ENOG4108IYU	L-aspartate oxidase
GTF75_02100	ENOG4105EMN	RNA polymerase sigma factor
GTF75_02115	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
GTF75_02120	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GTF75_02125	ENOG4105C3F	Signal peptidase i
GTF75_02135	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GTF75_02140	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
GTF75_02145	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GTF75_02165	ENOG4108K0B	C-di-gmp phosphodiesterase
GTF75_02170	ENOG4105BZU	Histidine kinase
GTF75_02180	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GTF75_02185	ENOG4105DXN	mazG family
GTF75_02190	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GTF75_02195	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GTF75_02215	ENOG4106MWK	domain protein
GTF75_02220	ENOG4105CJ3	phosphate transporter
GTF75_02225	ENOG4107IX6	phosphate transport regulator
GTF75_02230	ENOG4105I7R	Adenylate cyclase
GTF75_02235	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_02240	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
GTF75_02250	ENOG4105DFG	type I secretion outer membrane protein
GTF75_02255	ENOG41087AY	ADP-Ribose pyrophosphatase
GTF75_02260	ENOG4108SX3	cytoplasmic protein
GTF75_02265	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GTF75_02270	ENOG4105IPS	esterase
GTF75_02275	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GTF75_02280	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GTF75_02290	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
GTF75_02295	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GTF75_02300	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
GTF75_02305	ENOG4105D7Q	type ii secretion system
GTF75_02310	ENOG4107QHF	type ii secretion system protein e
GTF75_02320	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GTF75_02330	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
GTF75_02335	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GTF75_02340	ENOG4105T95	Thiol disulfide interChange protein
GTF75_02345	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GTF75_02350	ENOG4105CGH	5'-nucleotidase
GTF75_02355	ENOG41073TP	transcriptional regulator
GTF75_02360	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GTF75_02365	ENOG4107QSN	dihydrolipoamide acetyltransferase
GTF75_02370	ENOG4107QN2	dihydrolipoyl dehydrogenase
GTF75_02385	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GTF75_02390	ENOG4105CJN	penicillin-binding protein
GTF75_02395	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GTF75_02400	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GTF75_02410	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GTF75_02425	ENOG4105DFU	Cell wall formation (By similarity)
GTF75_02430	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
GTF75_02435	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GTF75_02440	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GTF75_02445	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GTF75_02455	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GTF75_02460	ENOG4105M6F	mutator MutT protein
GTF75_02465	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GTF75_02475	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GTF75_02480	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GTF75_02500	ENOG4107RRE	RNA-directed DNA polymerase
GTF75_02505	ENOG4105EJ9	Membrane
GTF75_02510	ENOG4105VP0	transcriptional regulator, lysR family
GTF75_02515	ENOG4105EN6	Membrane
GTF75_02520	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
GTF75_02530	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GTF75_02540	ENOG4105BZ8	glutamate synthase
GTF75_02545	ENOG4105CBC	glutamate synthase
GTF75_02560	ENOG4105N5T	Radical SAM Protein
GTF75_02570	ENOG4105BZU	Histidine kinase
GTF75_02575	ENOG41065U4	response regulator
GTF75_02585	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GTF75_02610	ENOG4105D98	threonine synthase
GTF75_02615	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
GTF75_02620	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GTF75_02625	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GTF75_02640	ENOG4105BZG	amino acid carrier protein
GTF75_02645	ENOG4105D1Q	UPF0246 protein
GTF75_02655	ENOG4105EYA	deoxyribonuclease
GTF75_02660	ENOG4105D9N	nucleoside
GTF75_02670	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GTF75_02675	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
GTF75_02680	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
GTF75_02685	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GTF75_02695	ENOG4105EAC	phosphoserine phosphatase
GTF75_02705	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GTF75_02710	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GTF75_02715	ENOG4108IQE	Amp-dependent synthetase and ligase
GTF75_02720	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GTF75_02730	ENOG4105CNT	hydrolase family 2
GTF75_02735	ENOG41060NJ	transcriptional regulator
GTF75_02740	ENOG4108Y51	tRNA-binding protein
GTF75_02755	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GTF75_02760	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
GTF75_02770	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
GTF75_02775	ENOG4105X2V	dna damage-inducible protein
GTF75_02790	ENOG4105DSY	exodeoxyribonuclease V, gamma
GTF75_02795	ENOG4107QKA	exodeoxyribonuclease V beta
GTF75_02800	ENOG4107QYX	exodeoxyribonuclease v alpha
GTF75_02810	ENOG4107QZM	n-acetylglutamate synthase
GTF75_02820	ENOG4105CA3	membrane-bound lytic murein transglycosylase
GTF75_02825	ENOG4105CUZ	uba thif-type nad fad binding protein
GTF75_02830	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GTF75_02835	ENOG4105C9B	Cysteine desulfurase
GTF75_02840	ENOG4107S0N	DJ-1 family
GTF75_02845	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
GTF75_02850	ENOG4105DRB	nucleoside-specific channel-forming protein
GTF75_02860	ENOG4105K6V	RNA polymerase
GTF75_02870	ENOG4105EYM	Major Facilitator superfamily
GTF75_02875	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GTF75_02885	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GTF75_02890	ENOG4105M85	Bola protein
GTF75_02895	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GTF75_02900	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GTF75_02905	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GTF75_02910	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GTF75_02915	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GTF75_02920	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
GTF75_02925	ENOG4105CJ2	(LipO)protein
GTF75_02955	ENOG4105BZU	Histidine kinase
GTF75_02960	ENOG4105C8J	)-transporter
GTF75_02970	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GTF75_02975	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GTF75_02980	ENOG4105CIN	aminoacyl-histidine dipeptidase
GTF75_02985	ENOG4105C7N	Xanthine uracil vitamin C permease
GTF75_02990	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
GTF75_02995	ENOG4108DJV	Fermentation respiration switch protein
GTF75_03000	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
GTF75_03005	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GTF75_03010	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GTF75_03015	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GTF75_03020	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GTF75_03035	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GTF75_03040	ENOG4107YIM	Involved in the transcription termination process (By similarity)
GTF75_03045	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GTF75_03050	ENOG4108ZAI	phosphatidylglycerophosphatase a
GTF75_03055	ENOG4108T8E	UPF0325 protein
GTF75_03060	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
GTF75_03065	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GTF75_03070	ENOG4105CE9	30S ribosomal protein S2
GTF75_03075	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GTF75_03080	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GTF75_03085	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GTF75_03090	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GTF75_03095	ENOG4105KNE	Phosphatidate cytidylyltransferase
GTF75_03100	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GTF75_03105	ENOG4105DZP	Membrane-associated zinc metalloprotease
GTF75_03115	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
GTF75_03120	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GTF75_03125	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GTF75_03130	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GTF75_03135	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GTF75_03140	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GTF75_03145	ENOG4105C0B	DNA polymerase III (alpha subunit)
GTF75_03150	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GTF75_03155	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GTF75_03160	ENOG4105N7H	Cytochrome
GTF75_03165	ENOG4105PY6	Phenolic acid decarboxylase
GTF75_03170	ENOG4108YZA	Nitrogen regulatory protein pii
GTF75_03175	ENOG4107NA1	Endonuclease Exonuclease phosphatase
GTF75_03180	ENOG4105E9H	Lytic Murein transglycosylase
GTF75_03185	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GTF75_03190	ENOG4105D1A	Methyltransferase
GTF75_03195	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GTF75_03200	ENOG4107RZZ	dna polymerase iii epsilon subunit
GTF75_03210	ENOG4107QPN	acyl-Coa dehydrogenase
GTF75_03215	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GTF75_03220	ENOG4105E7A	Glutamine amidotransferase
GTF75_03225	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GTF75_03230	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GTF75_03235	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GTF75_03240	ENOG4105BZU	Histidine kinase
GTF75_03245	ENOG4105FE9	pseudouridine synthase
GTF75_03250	ENOG4108DG9	Smr protein MutS2
GTF75_03265	ENOG4105MBR	gumn family
GTF75_03270	ENOG4105E2D	ec 3.2.1.52
GTF75_03280	ENOG4105C59	p-type ATPase
GTF75_03285	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GTF75_03290	ENOG4105UYK	outer membrane protein a
GTF75_03300	ENOG4107RBR	Receptor
GTF75_03305	ENOG4105Q26	Siderophore-interacting protein
GTF75_03310	ENOG4105C0W	non-ribosomal peptide synthetase
GTF75_03345	ENOG4107R88	Chemotaxis protein (CheV)
GTF75_03350	ENOG4105BZU	Histidine kinase
GTF75_03355	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GTF75_03360	ENOG4108ZC9	flagellar basal-body rod protein flgc
GTF75_03365	ENOG4105W00	Flagellar hook capping protein
GTF75_03370	ENOG4105BZE	flagellar hook protein, FlgE
GTF75_03375	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GTF75_03380	ENOG4105CGA	flagellar basal-body rod protein FlgG
GTF75_03385	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GTF75_03390	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GTF75_03395	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GTF75_03410	ENOG4105I03	Flagellin
GTF75_03415	ENOG4105I03	Flagellin
GTF75_03500	ENOG4105C3G	gtp-binding protein
GTF75_03505	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GTF75_03510	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GTF75_03515	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GTF75_03520	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
GTF75_03525	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GTF75_03530	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GTF75_03535	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GTF75_03540	ENOG4108YY7	Invasion gene expression up-regulator SirB
GTF75_03545	ENOG41063JG	Transcriptional regulator
GTF75_03550	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GTF75_03555	ENOG4105CGH	5'-nucleotidase
GTF75_03560	ENOG4108Z66	YbaK ebsC protein
GTF75_03565	ENOG4105C2W	permease
GTF75_03580	ENOG4105CS1	NAD(P)H quinone oxidoreductase
GTF75_03585	ENOG4105K89	arsenate reductase
GTF75_03590	ENOG4105ERG	peptidase m48, ste24p
GTF75_03605	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_03610	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GTF75_03625	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GTF75_03645	ENOG4105KUZ	arsenate reductase
GTF75_03660	ENOG4105QZU	Inner membrane protein YfeZ
GTF75_03665	ENOG4105EZR	dyp-type peroxidase family protein
GTF75_03670	ENOG4105I03	Flagellin
GTF75_03675	ENOG4105I03	Flagellin
GTF75_03680	ENOG4105I03	Flagellin
GTF75_03685	ENOG41063QE	flagellar protein FlaG
GTF75_03690	ENOG4107W9T	flagellar hook-associated
GTF75_03700	ENOG4105MQ3	flagellar protein FliS
GTF75_03710	ENOG4105BZU	Histidine kinase
GTF75_03720	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
GTF75_03725	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GTF75_03730	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GTF75_03735	ENOG4105W2B	Flagellar assembly protein
GTF75_03740	ENOG4108JIR	Flagellum-specific ATP synthase
GTF75_03760	ENOG4105X6C	Flagellar basal body-associated protein FliL
GTF75_03765	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GTF75_03770	ENOG4105DD5	Flagellar motor switch protein
GTF75_03775	ENOG4105VTB	flagellar biosynthesis protein fliO
GTF75_03780	ENOG4105CN7	Flagellar biosynthetic protein FliP
GTF75_03785	ENOG4105VS8	Flagellar biosynthetic protein fliq
GTF75_03790	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GTF75_03795	ENOG4105D00	flagellar biosynthetic protein flhB
GTF75_03800	ENOG4108DG9	Smr protein MutS2
GTF75_03805	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
GTF75_03810	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GTF75_03815	ENOG4105EN6	Membrane
GTF75_03820	ENOG4108BPE	-transporting atpase
GTF75_03825	ENOG4105MH2	YfcL protein
GTF75_03830	ENOG4105Q8W	reductase
GTF75_03840	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GTF75_03845	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
GTF75_03850	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GTF75_03855	ENOG41090R7	Ferric uptake
GTF75_03865	ENOG4105CMU	LysR family (Transcriptional regulator
GTF75_03870	ENOG4105VAW	lrga family
GTF75_03875	ENOG41067MG	lrgb family
GTF75_03880	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
GTF75_03890	ENOG4105EV9	Alpha Beta Hydrolase
GTF75_03895	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
GTF75_03900	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
GTF75_03910	ENOG4107QNR	UPF0135 protein
GTF75_03915	ENOG4105BZN	citrate synthase
GTF75_03920	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
GTF75_03925	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
GTF75_03930	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
GTF75_03935	ENOG4105E33	succinate dehydrogenase
GTF75_03940	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GTF75_03945	ENOG4105C7S	Dehydrogenase
GTF75_03950	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GTF75_03955	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GTF75_03960	ENOG4105FAV	ABC, transporter
GTF75_03965	ENOG4105FDK	ABC transporter
GTF75_03970	ENOG4105NXV	High-affinity zinc uptake system protein
GTF75_03975	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
GTF75_03980	ENOG4105XFK	Ferrous iron transport protein A
GTF75_04000	ENOG4105C75	arginyL-tRNA synthetase
GTF75_04010	ENOG4108JQM	Insulinase (Peptidase family M16)
GTF75_04015	ENOG4108BY2	phosphohistidine phosphatase
GTF75_04020	ENOG4105D7B	Flagellar biosynthesis protein flha
GTF75_04025	ENOG4105FZW	flagellar biosynthesis regulator FlhF
GTF75_04035	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GTF75_04040	ENOG4108VYJ	response regulator receiver protein
GTF75_04045	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
GTF75_04055	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GTF75_04060	ENOG4107QJE	Chromosome Partitioning Protein
GTF75_04070	ENOG4108V3W	Chemotaxis protein, CheW
GTF75_04080	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
GTF75_04085	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
GTF75_04090	ENOG41060IM	Heme exporter protein
GTF75_04095	ENOG41067VX	Heme exporter protein
GTF75_04100	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
GTF75_04105	ENOG4105DA4	cytochrome c-type biogenesis protein
GTF75_04110	ENOG4107QX9	Thiol disulfide interChange protein
GTF75_04115	ENOG4105KWW	Biogenesis protein
GTF75_04125	ENOG410903C	(LipO)protein
GTF75_04140	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GTF75_04145	ENOG4105M2J	Glutaredoxin
GTF75_04150	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GTF75_04155	ENOG4105DGU	Histone deacetylase
GTF75_04170	ENOG4105E68	Sulfatase
GTF75_04175	ENOG4105YDX	UPF0352 protein
GTF75_04180	ENOG4106V8H	Nucleoid-associated protein
GTF75_04190	ENOG4105DFD	Na H antiporter
GTF75_04195	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GTF75_04200	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GTF75_04205	ENOG4105C0A	alcohol dehydrogenase
GTF75_04215	ENOG4105CHH	sulfate transporter
GTF75_04220	ENOG4105C03	ribonuclease
GTF75_04225	ENOG4105EI2	Pseudouridine synthase
GTF75_04230	ENOG4108UHJ	MAF-like protein
GTF75_04235	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
GTF75_04240	ENOG4105VGS	50s ribosomal protein l32
GTF75_04245	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GTF75_04250	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GTF75_04255	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GTF75_04260	ENOG4105CHR	reductase
GTF75_04265	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GTF75_04270	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GTF75_04275	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
GTF75_04280	ENOG4105HHA	aminodeoxychorismate lyase
GTF75_04285	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GTF75_04290	ENOG4107QRG	dna polymerase iii
GTF75_04295	ENOG4105F8V	Hydrolase, tatD family
GTF75_04300	ENOG4105CI1	PTS System
GTF75_04310	ENOG4105C8J	)-transporter
GTF75_04325	ENOG4108NRW	Phospholipase, patatin family
GTF75_04330	ENOG4105CA9	Pyruvate kinase
GTF75_04335	ENOG4105DAG	ROK family
GTF75_04355	ENOG4105DHI	Methyltransferase
GTF75_04365	ENOG4105DSB	aldose 1-epimerase
GTF75_04370	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GTF75_04375	ENOG4105E0X	reductase
GTF75_04385	ENOG4105VUT	cytoplasmic protein
GTF75_04390	ENOG4105HDK	L-asparaginase
GTF75_04395	ENOG4105D07	Signal peptide peptidase, SppA
GTF75_04400	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GTF75_04405	ENOG4105CIY	formyltetrahydrofolate deformylase
GTF75_04415	ENOG4105DVT	helicase
GTF75_04420	ENOG41072GX	Peptidase M22 Glycoprotease
GTF75_04435	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GTF75_04440	ENOG4105CEY	Amp-dependent synthetase and ligase
GTF75_04445	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
GTF75_04465	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GTF75_04470	ENOG4105DK2	UPF0207 protein
GTF75_04475	ENOG4105CHM	Aminotransferase
GTF75_04480	ENOG4105E4F	Isochorismate synthase
GTF75_04485	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GTF75_04490	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
GTF75_04495	ENOG4108IPT	Naphthoate synthase
GTF75_04505	ENOG4105CEY	Amp-dependent synthetase and ligase
GTF75_04510	ENOG4105DKK	Benzoate
GTF75_04515	ENOG4108JCI	Transcriptional regulator
GTF75_04520	ENOG4108N3W	hemolysin secretion protein
GTF75_04530	ENOG4107S74	Lysophospholipid transporter LplT
GTF75_04555	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
GTF75_04560	ENOG4107QMS	site-determining protein
GTF75_04565	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GTF75_04570	ENOG4105VNG	YcgL domain-containing protein
GTF75_04575	ENOG4105CVE	Lytic murein transglycosylase
GTF75_04580	ENOG4105JQN	Transcriptional regulator
GTF75_04585	ENOG4105D9N	nucleoside
GTF75_04590	ENOG410662T	chitinase
GTF75_04595	ENOG4105CUW	cytochrome C-TYPE protein
GTF75_04600	ENOG4107QY8	reductase
GTF75_04610	ENOG4105JQN	Transcriptional regulator
GTF75_04625	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GTF75_04660	ENOG4108HPI	phosphatidate Cytidylyltransferase
GTF75_04670	ENOG4105BZU	Histidine kinase
GTF75_04680	ENOG4105CNG	UPF0061 protein
GTF75_04685	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
GTF75_04690	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
GTF75_04695	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GTF75_04700	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GTF75_04715	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GTF75_04720	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GTF75_04725	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GTF75_04730	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GTF75_04735	ENOG4105K70	DNA-binding protein
GTF75_04740	ENOG4105EIN	peptidylprolyl cis-trans isomerase
GTF75_04745	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
GTF75_04750	ENOG4105CAT	Cytidine monophosphate kinase
GTF75_04755	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GTF75_04760	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GTF75_04765	ENOG4105Q4A	inner membrane protein yciS
GTF75_04770	ENOG4105CFV	Tetratricopeptide repeat protein
GTF75_04780	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
GTF75_04790	ENOG4107R11	Transcriptional regulator
GTF75_04800	ENOG4105DCF	alanine dehydrogenase
GTF75_04805	ENOG4105EW9	transcriptional regulator AsnC family
GTF75_04810	ENOG4105CNU	cell division protein FtsK
GTF75_04815	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
GTF75_04820	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GTF75_04825	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
GTF75_04835	ENOG4108NVR	Methyl-accepting chemotaxis
GTF75_04840	ENOG4105K59	histidine triad (HIT) protein
GTF75_04865	ENOG4105D0Y	UPF0227 protein
GTF75_04870	ENOG4105CEP	NADH dehydrogenase
GTF75_04880	ENOG4106M3D	hemolysin
GTF75_04890	ENOG4108JA2	transcriptioN-repair coupling factor
GTF75_04900	ENOG4105D60	lipoprotein releasing system transmembrane protein
GTF75_04905	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GTF75_04910	ENOG4105D60	lipoprotein releasing system transmembrane protein
GTF75_04920	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
GTF75_04925	ENOG4105BZ1	(ABC) transporter
GTF75_04930	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GTF75_04935	ENOG4105W49	UPF0434 protein
GTF75_04940	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GTF75_04945	ENOG4105ED1	spovr family
GTF75_04950	ENOG4106AKX	UPF0229 protein
GTF75_04955	ENOG4105CYN	Serine protein kinase
GTF75_04960	ENOG4105XWI	UPF0304 protein
GTF75_04970	ENOG4105F1A	Pyruvate formate-lyase
GTF75_04975	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_04985	ENOG4105C6N	Formate acetyltransferase
GTF75_04995	ENOG4108JEH	abc transporter atp-binding protein
GTF75_05000	ENOG4105E89	ABC transporter
GTF75_05005	ENOG4105DSP	amino acid AbC transporter
GTF75_05010	ENOG4106YG3	ABC transporter
GTF75_05015	ENOG4105CGK	Exodeoxyribonuclease III
GTF75_05020	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_05025	ENOG4106428	Protein of unknown function (DUF2496)
GTF75_05030	ENOG4108URS	primosomal replication protein n''
GTF75_05035	ENOG4105EJ9	Membrane
GTF75_05040	ENOG4105DVT	helicase
GTF75_05045	ENOG4105ZU8	porin-like protein H
GTF75_05055	ENOG4105K5B	UPF0225 protein
GTF75_05060	ENOG4105D58	Diguanylate phosphodiesterase
GTF75_05065	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
GTF75_05070	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GTF75_05075	ENOG4105C8N	cysteinyl-tRNA synthetase
GTF75_05080	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GTF75_05085	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GTF75_05095	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GTF75_05100	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GTF75_05110	ENOG4105KJB	cyd operon protein YbgE
GTF75_05115	ENOG4107YD3	Thioesterase
GTF75_05120	ENOG4105E02	MotA TolQ exbB proton channel
GTF75_05125	ENOG4105M8F	Biopolymer transport protein exbD tolR
GTF75_05135	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
GTF75_05140	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GTF75_05150	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GTF75_05160	ENOG4105BZU	Histidine kinase
GTF75_05165	ENOG4108RNS	Exports L-alanine (By similarity)
GTF75_05170	ENOG4105EIP	mannose-6-phosphate isomerase
GTF75_05175	ENOG4105DM4	PTS System
GTF75_05180	ENOG4106R3P	AraC family transcriptional regulator
GTF75_05190	ENOG4108YRF	PTS System
GTF75_05195	ENOG4105DM4	PTS System
GTF75_05200	ENOG4105DM4	PTS System
GTF75_05210	ENOG4105C26	Dehydrogenase
GTF75_05215	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
GTF75_05220	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GTF75_05230	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GTF75_05350	ENOG4108NYK	Tape measure protein
GTF75_05370	ENOG4108YGG	dna repair protein
GTF75_05380	ENOG4108478	ec 3.2.1.18
GTF75_05385	ENOG4105CE4	GlcNAc 6-P deacetylase
GTF75_05390	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
GTF75_05400	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
GTF75_05405	ENOG41069H7	transport system small permease component
GTF75_05410	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GTF75_05420	ENOG4105QEK	Transcriptional regulator
GTF75_05425	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
GTF75_05430	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
GTF75_05450	ENOG4105CVR	type I restriction-modification system
GTF75_05480	ENOG4105DZR	Type I site-specific deoxyribonuclease
GTF75_05500	ENOG4105C0D	helicase
GTF75_05505	ENOG4105DFP	Integrase
GTF75_05510	ENOG4105DFP	Integrase
GTF75_05535	ENOG4105DY2	Paraquat-inducible protein b
GTF75_05540	ENOG4105F1S	paraquat-inducible protein a
GTF75_05565	ENOG4108R86	Transcriptional regulator
GTF75_05570	ENOG4105C26	Dehydrogenase
GTF75_05575	ENOG4105MTM	Protein of unknown function (DUF1496)
GTF75_05590	ENOG41067SE	Tetr family transcriptional regulator
GTF75_05595	ENOG4107QPN	acyl-Coa dehydrogenase
GTF75_05605	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GTF75_05625	ENOG4105RKX	Protein of unknown function (DUF2498)
GTF75_05630	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GTF75_05635	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GTF75_05640	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GTF75_05660	ENOG4105HP8	regulator of competence-specific genes
GTF75_05665	ENOG4105ETE	Transcriptional regulator (LacI family
GTF75_05670	ENOG4108SBI	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
GTF75_05675	ENOG4106WF9	DNA-binding transcriptional regulator TorR
GTF75_05680	ENOG4107S90	membrAne
GTF75_05685	ENOG4106371	Methyltransferase
GTF75_05695	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
GTF75_05705	ENOG4105EW9	transcriptional regulator AsnC family
GTF75_05715	ENOG4105CCT	upf0313 protein
GTF75_05740	ENOG4105DZ2	Transcriptional regulator
GTF75_05745	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GTF75_05755	ENOG4105K9H	YciI-like protein
GTF75_05760	ENOG4105NAU	thioesterase Superfamily protein
GTF75_05775	ENOG4105GFG	DUF218 domain
GTF75_05780	ENOG4107SRH	Nad-dependent epimerase dehydratase
GTF75_05790	ENOG4105TMB	Formate nitrite transporter
GTF75_05810	ENOG4107QY8	reductase
GTF75_05830	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
GTF75_05845	ENOG4108JQ2	peptide transport system atp-binding protein
GTF75_05850	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
GTF75_05855	ENOG4108EU3	peptide transport system, permease
GTF75_05860	ENOG4108I5W	peptide transport system, permease protein
GTF75_05865	ENOG4108J59	Extracellular solute-binding protein, family 5
GTF75_05870	ENOG4105E51	psp operon transcriptional activator
GTF75_05875	ENOG41087YS	Phage shock protein A
GTF75_05890	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GTF75_05905	ENOG4108R3E	Dna-3-methyladenine glycosylase i
GTF75_05910	ENOG4105C28	cystathionine
GTF75_05915	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
GTF75_05920	ENOG4105C8J	)-transporter
GTF75_05925	ENOG4108W1A	pseudouridine synthase
GTF75_05930	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
GTF75_05935	ENOG4108VGW	abc transporter atp-binding protein
GTF75_05940	ENOG4105CXZ	ABC transporter, permease
GTF75_05945	ENOG4105VNH	ABC transporter solute-binding protein
GTF75_05955	ENOG4105XZD	Fe-S protein
GTF75_05965	ENOG4107QWP	ABC-2 type transporter
GTF75_05970	ENOG4105CJ1	ABC, transporter
GTF75_05980	ENOG4105C44	Serine transporter
GTF75_05990	ENOG4105CJW	magnesium transporter
GTF75_06000	ENOG4105BZU	Histidine kinase
GTF75_06010	ENOG4105KXC	Collagenase
GTF75_06040	ENOG4108N3W	hemolysin secretion protein
GTF75_06055	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GTF75_06075	ENOG4105CFI	type iii restriction protein res subunit
GTF75_06080	ENOG4105I08	Pseudouridine synthase
GTF75_06085	ENOG4105C2C	drug resistance transporter, Bcr CflA
GTF75_06095	ENOG4105CGD	Nad-dependent epimerase dehydratase
GTF75_06100	ENOG4105UQX	Mate efflux family protein
GTF75_06105	ENOG4108I0Y	(ABC) transporter
GTF75_06120	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GTF75_06130	ENOG4105E3Q	saccharopine dehydrogenase
GTF75_06135	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
GTF75_06140	ENOG4105CDV	Ompa motb domain protein
GTF75_06145	ENOG4105DFG	type I secretion outer membrane protein
GTF75_06165	ENOG4105F04	LysR family Transcriptional regulator
GTF75_06175	ENOG4108VKG	metal-dependent hydrolase
GTF75_06180	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
GTF75_06190	ENOG41090FY	type IV pilus biogenesis stability protein PilW
GTF75_06195	ENOG4105CVG	Homoserine O-transsuccinylase
GTF75_06215	ENOG4107V40	secretion protein, HlyD family
GTF75_06230	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
GTF75_06235	ENOG4106YYS	transcriptional regulatory protein
GTF75_06245	ENOG4107R88	Chemotaxis protein (CheV)
GTF75_06290	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GTF75_06295	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GTF75_06300	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GTF75_06305	ENOG4106TD9	Diguanylate cyclase
GTF75_06310	ENOG4105BZU	Histidine kinase
GTF75_06320	ENOG4105C7K	acetolactate synthase
GTF75_06340	ENOG4105CH6	catalase
GTF75_06350	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GTF75_06360	ENOG4108TWJ	NADH dehydrogenase subunit 5
GTF75_06365	ENOG4105DUM	transcriptional regulator, lysR family
GTF75_06370	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
GTF75_06400	ENOG4105C9Q	fumarate hydratase class II
GTF75_06410	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GTF75_06415	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GTF75_06420	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GTF75_06425	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GTF75_06430	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GTF75_06440	ENOG4107QZV	Type I secretion membrane fusion protein
GTF75_06460	ENOG4105CS2	ec 3.2.1.21
GTF75_06465	ENOG4105DDV	Transcriptional regulator (LacI family
GTF75_06470	ENOG4105M4H	endoribonuclease L-psp
GTF75_06475	ENOG4105XEP	YhcH YjgK YiaL family protein
GTF75_06480	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
GTF75_06485	ENOG4105E98	transcriptional regulator DeoR family
GTF75_06490	ENOG4108IJ9	(ABC) transporter
GTF75_06495	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
GTF75_06525	ENOG4109015	Biopolymer transport protein exbD tolR
GTF75_06530	ENOG41067XB	TonB family
GTF75_06550	ENOG4107QI1	Mate efflux family protein
GTF75_06570	ENOG4107TT5	NLP P60 protein
GTF75_06575	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_06585	ENOG4106IUH	DTW domain containing protein
GTF75_06590	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
GTF75_06610	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GTF75_06615	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GTF75_06620	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GTF75_06625	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
GTF75_06635	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GTF75_06640	ENOG4105BZU	Histidine kinase
GTF75_06645	ENOG4105C5H	ABC transporter
GTF75_06650	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GTF75_06670	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
GTF75_06680	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GTF75_06685	ENOG4105QAX	Iron-sulfur
GTF75_06700	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
GTF75_06705	ENOG4108VPT	UPF0234 protein
GTF75_06710	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GTF75_06725	ENOG4105QNR	S1 RNA binding domain protein
GTF75_06735	ENOG4105DY2	Paraquat-inducible protein b
GTF75_06740	ENOG4105H2K	paraquat-inducible protein a
GTF75_06745	ENOG4105BZ1	(ABC) transporter
GTF75_06750	ENOG4108ZGC	gaf domain protein
GTF75_06755	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
GTF75_06760	ENOG4105CN1	protease
GTF75_06770	ENOG4105CD8	aminopeptidase N
GTF75_06780	ENOG4105C7I	Dehydrogenase
GTF75_06785	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GTF75_06790	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
GTF75_06795	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GTF75_06805	ENOG4105C5H	ABC transporter
GTF75_06820	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
GTF75_06825	ENOG4105DAN	ATP-dependent protease
GTF75_06830	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
GTF75_06905	ENOG4105TIV	Cryptic phage CTXphi transcriptional repressor RstR
GTF75_06925	ENOG4105TIV	Cryptic phage CTXphi transcriptional repressor RstR
GTF75_06955	ENOG4105MQ5	zona occludens toxin
GTF75_06960	ENOG4107927	Cholera enterotoxin, A subunit
GTF75_06970	ENOG4105EUK	rtx toxin RtxA
GTF75_06975	ENOG4108RC6	RTX toxin
GTF75_07000	ENOG4105BZU	Histidine kinase
GTF75_07015	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
GTF75_07030	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
GTF75_07040	ENOG4105C59	p-type ATPase
GTF75_07055	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
GTF75_07060	ENOG4105Q9Y	Universal stress protein
GTF75_07085	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GTF75_07095	ENOG4105D38	putrescine abc transporter
GTF75_07100	ENOG4108HM4	ABC transporter
GTF75_07105	ENOG4107RUE	extracellular solute-binding protein family 1
GTF75_07120	ENOG4105BZG	amino acid carrier protein
GTF75_07125	ENOG410829K	Lysine exporter protein (Lyse ygga)
GTF75_07150	ENOG4105CS6	Rhs element vgr protein
GTF75_07155	ENOG4108WC9	type VI secretion system effector, hcp1 family
GTF75_07160	ENOG4105CTD	carboxy-peptidase
GTF75_07165	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_07170	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GTF75_07175	ENOG4105CW7	secretion protein, HlyD family
GTF75_07180	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GTF75_07190	ENOG4105C1J	atp-dependent rna helicase
GTF75_07200	ENOG4108N3W	hemolysin secretion protein
GTF75_07205	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_07210	ENOG4108V3W	Chemotaxis protein, CheW
GTF75_07215	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GTF75_07225	ENOG4105BZU	Histidine kinase
GTF75_07235	ENOG4105CBS	Chea signal transduction histidine kinase
GTF75_07250	ENOG4108NVR	Methyl-accepting chemotaxis
GTF75_07255	ENOG4105KPY	Small multidrug resistance protein
GTF75_07260	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GTF75_07265	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GTF75_07270	ENOG4105EJC	lysr family transcriptional regulator
GTF75_07280	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
GTF75_07285	ENOG4105R8A	Heat shock protein
GTF75_07295	ENOG4105CQ7	ATP-dependent helicase
GTF75_07315	ENOG4105BZU	Histidine kinase
GTF75_07325	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GTF75_07330	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GTF75_07335	ENOG4105BZU	Histidine kinase
GTF75_07345	ENOG4105BZU	Histidine kinase
GTF75_07365	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GTF75_07370	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GTF75_07375	ENOG410667J	hydrolase
GTF75_07385	ENOG4107QXX	ABC transporter
GTF75_07390	ENOG4105EZ7	amino acid ABC transporter
GTF75_07395	ENOG4105DRP	amino acid AbC transporter
GTF75_07400	ENOG4105CDA	abc transporter atp-binding protein
GTF75_07405	ENOG4108MN8	Membrane
GTF75_07410	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
GTF75_07415	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
GTF75_07420	ENOG4105DR4	Methyltransferase
GTF75_07425	ENOG4106TD9	Diguanylate cyclase
GTF75_07435	ENOG4105BZU	Histidine kinase
GTF75_07440	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GTF75_07445	ENOG4108RXX	maleylacetoacetate isomerase
GTF75_07455	ENOG4105F1J	Homogentisate 1,2-dioxygenase
GTF75_07460	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
GTF75_07465	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GTF75_07480	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GTF75_07485	ENOG4105C7F	AcnD-accessory protein PrpF
GTF75_07490	ENOG4108I0Z	Aconitate hydratase
GTF75_07495	ENOG4105BZN	citrate synthase
GTF75_07500	ENOG4105CR4	methylisocitrate lyase
GTF75_07535	ENOG4107SDZ	Galactoside transport system permease protein mglC
GTF75_07540	ENOG4105C2J	ABC transporter
GTF75_07565	ENOG4107EXC	regulatoR
GTF75_07570	ENOG4105EB3	Histidine kinase
GTF75_07575	ENOG4105RW8	MltA-interacting MipA family protein
GTF75_07580	ENOG4108MJ5	VirK protein
GTF75_07585	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GTF75_07590	ENOG4105BZU	Histidine kinase
GTF75_07595	ENOG4105C8P	)-transporter
GTF75_07600	ENOG4108NVR	Methyl-accepting chemotaxis
GTF75_07605	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GTF75_07620	ENOG4105D9U	N-acetyltransferase
GTF75_07625	ENOG4108JU8	Transcriptional regulator
GTF75_07635	ENOG4105CM6	amino acid regulated cytosolic protein
GTF75_07650	ENOG4105CRQ	synthase (Component I)
GTF75_07655	ENOG4105P8F	nudix hydrolase
GTF75_07660	ENOG4105C44	Serine transporter
GTF75_07665	ENOG4105EJQ	L-serine dehydratase
GTF75_07670	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
GTF75_07675	ENOG4108NVR	Methyl-accepting chemotaxis
GTF75_07680	ENOG4105C5S	asparaginyl-tRNA synthetase
GTF75_07690	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GTF75_07695	ENOG4105CGF	Aromatic amino acid aminotransferase
GTF75_07710	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_07715	ENOG4105DJ9	glucan biosynthesis protein
GTF75_07720	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
GTF75_07725	ENOG41060NJ	transcriptional regulator
GTF75_07735	ENOG4105F8D	glycoside hydrolase family 4
GTF75_07740	ENOG4105VCP	PTS System
GTF75_07750	ENOG4105VZJ	PTS System
GTF75_07760	ENOG4105C94	Transporter
GTF75_07765	ENOG41067TZ	transcriptional regulator, MarR family
GTF75_07780	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GTF75_07790	ENOG4105CH5	extracellular solute-binding protein, family 7
GTF75_07805	ENOG4105C5X	domain protein
GTF75_07810	ENOG4105EAQ	(twin-arginine translocation) pathway signal
GTF75_07815	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
GTF75_07840	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
GTF75_07850	ENOG4105S8Q	sugar efflux transporter
GTF75_07860	ENOG4105C72	UPF0176 protein
GTF75_07865	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GTF75_07870	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GTF75_07875	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GTF75_07880	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GTF75_07885	ENOG4107QK7	reductase
GTF75_07910	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_07930	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
GTF75_07945	ENOG4108YZT	Adenosylcobinamide kinase
GTF75_07950	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
GTF75_07955	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
GTF75_07960	ENOG4105E0X	reductase
GTF75_07965	ENOG4108ETY	sodium dicarboxylate symporter
GTF75_07970	ENOG4105CJB	Exodeoxyribonuclease I
GTF75_07975	ENOG4105VAW	lrga family
GTF75_07980	ENOG41067MG	lrgb family
GTF75_08010	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GTF75_08015	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GTF75_08020	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GTF75_08060	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GTF75_08065	ENOG4105WH1	Two component transcriptional regulator luxr family
GTF75_08070	ENOG4105CQ2	DNA polymerase
GTF75_08075	ENOG4105BZU	Histidine kinase
GTF75_08085	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GTF75_08090	ENOG4108W5H	UPF0263 protein
GTF75_08100	ENOG4105CZE	histidine utilization repressor
GTF75_08105	ENOG4105CI2	imidazolone-5-propionate hydrolase
GTF75_08110	ENOG41088SP	formiminoglutamate hydrolase
GTF75_08115	ENOG4105CGP	Urocanate hydratase
GTF75_08120	ENOG4105C84	Histidine ammonia-lyase
GTF75_08130	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
GTF75_08140	ENOG4105CQB	FAD linked oxidase domain protein
GTF75_08155	ENOG4108ZG0	Ompa motb domain protein
GTF75_08175	ENOG4105C8V	SAICAR synthetase
GTF75_08185	ENOG4107R1I	NAD-dependent malic enzyme
GTF75_08195	ENOG4107GZ4	SanA protein
GTF75_08200	ENOG4105BZU	Histidine kinase
GTF75_08205	ENOG4105C9B	Cysteine desulfurase
GTF75_08215	ENOG4105C3M	thioredoxin reductase
GTF75_08220	ENOG4108JJ9	ABC, transporter
GTF75_08225	ENOG4108JJ8	(ABC) transporter
GTF75_08230	ENOG4105FE9	pseudouridine synthase
GTF75_08235	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GTF75_08240	ENOG4105DB7	PHP domain protein
GTF75_08250	ENOG4105CRQ	synthase (Component I)
GTF75_08255	ENOG4105DDQ	anthranilate synthase
GTF75_08260	ENOG4108I0Q	anthranilate phosphoribosyltransferase
GTF75_08265	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GTF75_08270	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GTF75_08275	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GTF75_08280	ENOG4105CK2	sodium dicarboxylate symporter
GTF75_08285	ENOG4107104	thymidine kinase
GTF75_08290	ENOG4105C9M	aspartyl-trna synthetase
GTF75_08295	ENOG41081XQ	Conserved Protein
GTF75_08300	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
GTF75_08305	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
GTF75_08310	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GTF75_08325	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GTF75_08335	ENOG4105CUX	Signal transduction histidine kinase
GTF75_08360	ENOG4105DWU	Membrane
GTF75_08370	ENOG4105DY8	decarboxylase
GTF75_08375	ENOG4106KNT	transcriptional regulator
GTF75_08380	ENOG4105C0A	alcohol dehydrogenase
GTF75_08385	ENOG41090BQ	Glutaredoxin
GTF75_08390	ENOG4105D0C	transport protein
GTF75_08395	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GTF75_08400	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GTF75_08405	ENOG4105VEQ	Cold shock protein
GTF75_08415	ENOG4108R99	pseudouridine synthase
GTF75_08420	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GTF75_08425	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GTF75_08430	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GTF75_08435	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GTF75_08440	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GTF75_08445	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GTF75_08450	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GTF75_08455	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GTF75_08460	ENOG4107S6Z	Na H antiporter
GTF75_08470	ENOG4107RE1	Inosine-guanosine kinase
GTF75_08475	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GTF75_08480	ENOG41075W9	High frequency lysogenization protein HflD homolog
GTF75_08485	ENOG4107QTF	adenylosuccinate lyase
GTF75_08495	ENOG4105RHG	
GTF75_08505	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GTF75_08520	ENOG4107FW0	short-chain dehydrogenase reductase
GTF75_08530	ENOG4105D0M	Protease HtpX homolog
GTF75_08540	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GTF75_08545	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GTF75_08550	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GTF75_08555	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GTF75_08560	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GTF75_08565	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GTF75_08570	ENOG4105D1H	recombination factor protein RarA
GTF75_08580	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GTF75_08585	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
GTF75_08590	ENOG4105BZU	Histidine kinase
GTF75_08595	ENOG4108JJB	ABC transporter
GTF75_08600	ENOG4105C7J	ABC transporter, permease
GTF75_08610	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GTF75_08615	ENOG4105PQ6	UPF0208 membrane protein
GTF75_08620	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GTF75_08625	ENOG4108DNC	Involved in acetate metabolism (By similarity)
GTF75_08630	ENOG4105CHF	Glutathione S-transferase
GTF75_08635	ENOG4108JQ7	(ABC) transporter
GTF75_08640	ENOG4105C3U	ABC transporter
GTF75_08645	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GTF75_08650	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GTF75_08655	ENOG4107QSI	ABC, transporter
GTF75_08670	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GTF75_08675	ENOG4105BZU	Histidine kinase
GTF75_08680	ENOG4105BZU	Histidine kinase
GTF75_08685	ENOG4105BZU	Histidine kinase
GTF75_08695	ENOG4107YTP	response regulator receiver protein
GTF75_08710	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GTF75_08725	ENOG4108V1U	phospholipid-binding protein
GTF75_08750	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GTF75_08755	ENOG41082YX	Transcriptional regulator, arsr family
GTF75_08765	ENOG4105BZU	Histidine kinase
GTF75_08785	ENOG4105C29	acyl-CoA thioesterase
GTF75_08790	ENOG4108XM1	transcriptional regulator AsnC family
GTF75_08800	ENOG4105ERU	peptidase
GTF75_08805	ENOG4105UBK	short-chain dehydrogenase reductase
GTF75_08810	ENOG4108ZZ3	UPF0260 protein
GTF75_08815	ENOG4105KRS	Proteinase inhibitor
GTF75_08820	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GTF75_08825	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GTF75_08830	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GTF75_08835	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GTF75_08840	ENOG4105WD1	Membrane
GTF75_08845	ENOG4105I93	response regulator
GTF75_08850	ENOG4105EJC	lysr family transcriptional regulator
GTF75_08855	ENOG41069NU	Nitroreductase
GTF75_08860	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GTF75_08865	ENOG4105CHU	acetyl-coa acetyltransferase
GTF75_08880	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GTF75_08885	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GTF75_08895	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
GTF75_08900	ENOG4108GAE	asmA family
GTF75_08905	ENOG4105DBI	uridine monophosphokinase
GTF75_08910	ENOG4105D1F	ATP-binding protein
GTF75_08915	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GTF75_08925	ENOG4108I5U	Uridine phosphorylase
GTF75_08940	ENOG4105BZU	Histidine kinase
GTF75_08945	ENOG4108ZAF	Molybdopterin
GTF75_08950	ENOG4105M00	molybdopterin converting factor, subunit 1
GTF75_08955	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GTF75_08960	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GTF75_08965	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GTF75_08970	ENOG4105CHW	UPF0052 protein
GTF75_08980	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GTF75_08985	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GTF75_09000	ENOG4108R3D	Electron transport complex
GTF75_09025	ENOG4105CSM	endonuclease III
GTF75_09030	ENOG4108UYE	Lactoylglutathione lyase
GTF75_09035	ENOG4106WH9	Protein of unknown function (DUF2753)
GTF75_09040	ENOG4105EIY	sodium-type flagellar protein motY
GTF75_09045	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
GTF75_09050	ENOG4105D3Y	Na H antiporter
GTF75_09055	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GTF75_09060	ENOG4105E96	Colicin v production protein
GTF75_09065	ENOG4108S3P	Sporulation domain protein
GTF75_09070	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GTF75_09075	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GTF75_09080	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GTF75_09095	ENOG4105CI1	PTS System
GTF75_09100	ENOG4105CE4	GlcNAc 6-P deacetylase
GTF75_09105	ENOG4105E2R	ROK family
GTF75_09110	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GTF75_09115	ENOG4105CAQ	asparagine synthetase
GTF75_09120	ENOG4105MDZ	Transcriptional activator rfaH
GTF75_09125	ENOG4105DUX	Transporter
GTF75_09130	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GTF75_09135	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GTF75_09140	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GTF75_09145	ENOG4108TU9	TRANSCRIPTIONal
GTF75_09160	ENOG4108RE9	Phosphodiesterase
GTF75_09165	ENOG4105ECP	epimerase
GTF75_09170	ENOG4105E1F	short-chain dehydrogenase reductase
GTF75_09175	ENOG4107QR8	Thioredoxin
GTF75_09180	ENOG4107QX8	SPFH domain, Band 7 family protein
GTF75_09185	ENOG4105G5H	Membrane
GTF75_09190	ENOG4108Z6Z	Transcriptional regulator
GTF75_09200	ENOG41081QG	Porin Gram-negative type
GTF75_09205	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GTF75_09210	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
GTF75_09215	ENOG4105EXN	Sulfate transport protein CysZ
GTF75_09220	ENOG4105C6T	cysteine synthase
GTF75_09225	ENOG4105KZ7	phosphocarrier protein hpr
GTF75_09230	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GTF75_09235	ENOG4105C5Y	PTS System
GTF75_09240	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GTF75_09245	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GTF75_09250	ENOG4105C9A	Phoh family
GTF75_09260	ENOG4108JU5	Magnesium and cobalt efflux protein
GTF75_09265	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GTF75_09270	ENOG4107PAI	alpha helical protein
GTF75_09275	ENOG4105C8T	Leucyl-tRNA synthetase
GTF75_09280	ENOG4108U2H	Rare lipoprotein B
GTF75_09285	ENOG4105DJF	DNA polymerase III, delta' subunit
GTF75_09290	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
GTF75_09295	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GTF75_09300	ENOG4105CJN	penicillin-binding protein
GTF75_09305	ENOG4105CNI	cell division protein FtsW
GTF75_09310	ENOG4105K6T	rare lipoprotein A
GTF75_09315	ENOG4105DZ1	carboxypeptidase
GTF75_09320	ENOG4108Z43	UPF0250 protein
GTF75_09325	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GTF75_09330	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GTF75_09340	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GTF75_09360	ENOG4105D75	Capsular exopolysaccharide family
GTF75_09365	ENOG4105DAY	polysaccharide export protein
GTF75_09375	ENOG4105D3Q	Sugar transferase
GTF75_09390	ENOG4108MA4	Peptidase M66
GTF75_09405	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
GTF75_09415	ENOG4105Q84	sucrose synthase
GTF75_09425	ENOG4105D7W	serine acetyltransferase
GTF75_09445	ENOG4108UW5	maltose o-acetyltransferase
GTF75_09455	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GTF75_09460	ENOG4107ZF2	Phosphatase
GTF75_09465	ENOG4105BZS	acriflavin resistance protein
GTF75_09495	ENOG4105CG3	alpha amylase, catalytic region
GTF75_09500	ENOG4105C5Y	PTS System
GTF75_09505	ENOG4105D4X	repressor
GTF75_09510	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
GTF75_09515	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GTF75_09520	ENOG4108UMI	ABC transporter, permease
GTF75_09525	ENOG4105D01	(LipO)protein
GTF75_09530	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
GTF75_09535	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
GTF75_09540	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GTF75_09550	ENOG4105BZU	Histidine kinase
GTF75_09555	ENOG4105EWT	decarboxylase family
GTF75_09560	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
GTF75_09565	ENOG4105M08	Membrane
GTF75_09570	ENOG4105ETT	transcriptional Regulator, LysR family
GTF75_09575	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GTF75_09580	ENOG4106VK6	Flagellar motor protein
GTF75_09585	ENOG4105E14	MotA TolQ exbB proton channel
GTF75_09595	ENOG4105CTB	Polyprenyl synthetase
GTF75_09600	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GTF75_09605	ENOG4105DR9	pseudouridine synthase
GTF75_09610	ENOG4105WP7	tRNA pseudouridine synthase C
GTF75_09625	ENOG4108428	Inherit from COG: -acetyltransferase
GTF75_09635	ENOG4108UPT	UPF0178 protein
GTF75_09640	ENOG4105CFC	Transporter
GTF75_09650	ENOG4105NRA	50s ribosomal protein l31 type b
GTF75_09655	ENOG4108R96	Methyltransferase, YaeB family
GTF75_09660	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GTF75_09680	ENOG4108RS6	transposase
GTF75_09685	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GTF75_09695	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GTF75_09700	ENOG4108Z6B	deaminase
GTF75_09705	ENOG4105CFC	Transporter
GTF75_09735	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GTF75_09740	ENOG4105CFG	Acts as a chaperone (By similarity)
GTF75_09745	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GTF75_09750	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GTF75_09755	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GTF75_09760	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GTF75_09765	ENOG4105VDB	UPF0125 protein
GTF75_09770	ENOG4108Z1B	Cyclase dehydrase
GTF75_09775	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GTF75_09785	ENOG4105DFP	Integrase
GTF75_09795	ENOG4105DFP	Integrase
GTF75_09800	ENOG4105F88	accessory colonization factor AcfD
GTF75_09810	ENOG4105DR5	peptidase
GTF75_09825	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_09830	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
GTF75_09845	ENOG4108VEY	type ii secretion system
GTF75_09850	ENOG4107QHF	type ii secretion system protein e
GTF75_09870	ENOG4105GRU	toxin co-regulated pilus biosynthesis outer membrane protein C
GTF75_09885	ENOG4105XB6	Toxin coregulated pilin
GTF75_09900	ENOG4107RK6	Methyl-accepting chemotaxis
GTF75_09905	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
GTF75_09925	ENOG4105C26	Dehydrogenase
GTF75_09980	ENOG4105DZ0	fad dependent oxidoreductase
GTF75_09985	ENOG4108Z4U	Ferredoxin
GTF75_10010	ENOG4105CHY	citrate lyase, alpha
GTF75_10015	ENOG4105CI0	Citrate lyase
GTF75_10025	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
GTF75_10030	ENOG4105D2K	citrate carrier protein
GTF75_10040	ENOG4107QSA	Oxaloacetate decarboxylase
GTF75_10045	ENOG4105D9Q	decarboxylase (Beta subunit)
GTF75_10050	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
GTF75_10055	ENOG4106YYS	transcriptional regulatory protein
GTF75_10080	ENOG4105BZG	amino acid carrier protein
GTF75_10085	ENOG4105EUZ	Beta-lactamase domain protein
GTF75_10090	ENOG41064T2	transcriptional regulator, lysR family
GTF75_10100	ENOG4105E0A	ABC, transporter
GTF75_10105	ENOG4105TVJ	transport system, permease
GTF75_10110	ENOG4105DQ5	transport system permease protein
GTF75_10115	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
GTF75_10125	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
GTF75_10130	ENOG4105E4F	Isochorismate synthase
GTF75_10135	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
GTF75_10140	ENOG4105WQI	isochorismatase
GTF75_10145	ENOG4106HK8	GPR1 FUN34 yaaH family protein
GTF75_10155	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GTF75_10160	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GTF75_10165	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GTF75_10180	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GTF75_10185	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GTF75_10190	ENOG4105N21	Membrane
GTF75_10195	ENOG4105CUT	histidyl-tRNA synthetase
GTF75_10200	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GTF75_10210	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GTF75_10215	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GTF75_10220	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GTF75_10225	ENOG4105WVQ	Fe-S assembly protein IscX
GTF75_10230	ENOG4108ZIT	Ferredoxin, 2FE-2S
GTF75_10235	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GTF75_10240	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
GTF75_10245	ENOG4108Z4V	iron-sulfur cluster assembly
GTF75_10250	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GTF75_10255	ENOG4105C3J	Cysteine desulfurase
GTF75_10260	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
GTF75_10265	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
GTF75_10270	ENOG4105ECY	inositol monophosphatase
GTF75_10275	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GTF75_10280	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GTF75_10285	ENOG4105VIE	preprotein translocase, subunit YajC
GTF75_10300	ENOG4105W87	Cbs domain
GTF75_10305	ENOG4108I9X	Isocitrate lyase
GTF75_10310	ENOG4107QP3	malate synthase g
GTF75_10315	ENOG4105C5Q	Transcriptional regulator
GTF75_10320	ENOG4105D3R	alkyl hydroperoxide reductase
GTF75_10325	ENOG4106N3A	copper homeostasis protein cutc
GTF75_10330	ENOG4105CSR	polyphosphate kinase 2
GTF75_10340	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GTF75_10345	ENOG4105E2Z	phosphate ABC transporter (Permease
GTF75_10350	ENOG4105C8U	phosphate abc transporter
GTF75_10355	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GTF75_10360	ENOG4105C9X	ppx gppa phosphatase
GTF75_10365	ENOG4105DJH	phosphate
GTF75_10370	ENOG4105BZU	Histidine kinase
GTF75_10375	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GTF75_10385	ENOG4105CFP	Peptidase U32
GTF75_10390	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GTF75_10430	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GTF75_10435	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GTF75_10440	ENOG4105C34	Pseudouridine synthase
GTF75_10445	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTF75_10450	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
GTF75_10460	ENOG4107XW0	Spermidine putrescine ABC transporter periplasmic spermidine putrescine-binding protein
GTF75_10465	ENOG4108K0B	C-di-gmp phosphodiesterase
GTF75_10475	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
GTF75_10480	ENOG4107SC1	transglycosylase
GTF75_10485	ENOG4105C5H	ABC transporter
GTF75_10500	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GTF75_10505	ENOG4108HRK	Histidine kinase
GTF75_10510	ENOG4108NEV	two component transcriptional regulator, LytTR family
GTF75_10520	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
GTF75_10525	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GTF75_10545	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GTF75_10550	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GTF75_10565	ENOG4105DTN	riboflavin biosynthesis protein ribF
GTF75_10570	ENOG4105CJR	Integral membrane protein (MviN
GTF75_10575	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GTF75_10580	ENOG41080HT	Transcriptional regulator, arsr family
GTF75_10585	ENOG41063Z6	transcriptional regulator, lysR family
GTF75_10600	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GTF75_10605	ENOG4105HF0	Membrane
GTF75_10610	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
GTF75_10615	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GTF75_10625	ENOG4105CPC	Aldo Keto reductase
GTF75_10635	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GTF75_10640	ENOG4105CRK	lysyL-tRNA synthetase
GTF75_10650	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GTF75_10660	ENOG4105C1J	atp-dependent rna helicase
GTF75_10750	ENOG4108KB1	transcriptional regulator, arac family
GTF75_10775	ENOG4108YGG	dna repair protein
GTF75_10800	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
GTF75_10820	ENOG4108UUM	single-stranded DNA-binding protein
GTF75_10835	ENOG4105RWS	endonuclease I
GTF75_10890	ENOG4105T95	Thiol disulfide interChange protein
GTF75_11025	ENOG4105KT5	UmuD protein
GTF75_11060	ENOG4108R0M	Aminoglycoside
GTF75_11140	ENOG4105BZU	Histidine kinase
GTF75_11155	ENOG4108YYD	acetyltransferase
GTF75_11165	ENOG4105BZU	Histidine kinase
GTF75_11200	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GTF75_11210	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GTF75_11215	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GTF75_11220	ENOG4105CHV	Transcription elongation factor NusA
GTF75_11225	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GTF75_11240	ENOG4105NTZ	Preprotein translocase subunit SecG
GTF75_11250	ENOG4105EEI	dihydropteroate synthase
GTF75_11255	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GTF75_11260	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GTF75_11265	ENOG4105HBR	Rna-binding protein
GTF75_11270	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GTF75_11275	ENOG4105FCK	Membrane
GTF75_11280	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
GTF75_11285	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GTF75_11290	ENOG4105DR5	peptidase
GTF75_11305	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GTF75_11310	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GTF75_11320	ENOG4105IPI	Membrane
GTF75_11325	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GTF75_11335	ENOG4107QRA	Extracellular solute-binding protein, family 5
GTF75_11345	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GTF75_11350	ENOG4105C3U	ABC transporter
GTF75_11355	ENOG4108JQ7	(ABC) transporter
GTF75_11365	ENOG4105RD7	BadF BadG BcrA BcrD
GTF75_11370	ENOG4105E2D	ec 3.2.1.52
GTF75_11375	ENOG4105E2V	Glycosyltransferase 36
GTF75_11385	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GTF75_11410	ENOG4105XTV	UPF0231 protein
GTF75_11415	ENOG4107QIJ	Aconitate hydratase 2
GTF75_11420	ENOG4105D78	K07001 NTE family protein
GTF75_11425	ENOG4105BZ4	penicillin-binding protein
GTF75_11430	ENOG4105CQ7	ATP-dependent helicase
GTF75_11440	ENOG4105PW4	Sugar fermentation stimulation protein homolog
GTF75_11445	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GTF75_11450	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
GTF75_11455	ENOG4105DJ0	Poly(A) Polymerase
GTF75_11460	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GTF75_11465	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GTF75_11470	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GTF75_11475	ENOG4105E3A	(ABC) transporter
GTF75_11480	ENOG4105DA5	(ABC) transporter
GTF75_11485	ENOG4105CHH	sulfate transporter
GTF75_11490	ENOG41077A9	carbonic anhydrase
GTF75_11495	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GTF75_11500	ENOG410630P	Transcriptional regulator
GTF75_11505	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GTF75_11510	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
GTF75_11515	ENOG41082RQ	UPF0102 protein
GTF75_11520	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GTF75_11525	ENOG4105W4M	Transport-associated protein
GTF75_11530	ENOG4105KB2	stringent starvation protein b
GTF75_11535	ENOG4107MKT	Stringent starvation protein a
GTF75_11540	ENOG4105EIX	cytochrome c1
GTF75_11545	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GTF75_11550	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GTF75_11555	ENOG4108UJD	30S ribosomal protein S9
GTF75_11560	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GTF75_11565	ENOG4105D6Z	AFG1 family ATPase
GTF75_11575	ENOG4105C0H	protease
GTF75_11580	ENOG4105C0H	protease
GTF75_11585	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GTF75_11590	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GTF75_11595	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GTF75_11600	ENOG4105K5M	30s ribosomal protein S16
GTF75_11605	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GTF75_11610	ENOG4106KVJ	cytochrome C assembly protein
GTF75_11615	ENOG4108JU6	CBS domain protein
GTF75_11620	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GTF75_11625	ENOG4105D9M	gamma-glutamylcysteine synthetase
GTF75_11635	ENOG4105W39	Membrane
GTF75_11645	ENOG4105D9Q	decarboxylase (Beta subunit)
GTF75_11650	ENOG4107QSA	Oxaloacetate decarboxylase
GTF75_11700	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GTF75_11705	ENOG4105CFH	Aspartokinase
GTF75_11710	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GTF75_11720	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GTF75_11730	ENOG4108IJ6	ABC transporter
GTF75_11735	ENOG4105ECW	sulfate abc transporter
GTF75_11740	ENOG4108I5D	sulfate abc transporter
GTF75_11745	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
GTF75_11750	ENOG4105C6T	cysteine synthase
GTF75_11755	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GTF75_11760	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GTF75_11765	ENOG4108K5P	(LipO)protein
GTF75_11770	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GTF75_11775	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GTF75_11780	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
GTF75_11785	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GTF75_11790	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GTF75_11800	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GTF75_11805	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GTF75_11810	ENOG4107ZVW	dihydroneopterin aldolase
GTF75_11815	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GTF75_11825	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GTF75_11830	ENOG4105VCC	30S ribosomal protein S21
GTF75_11835	ENOG4105KTH	gatB Yqey
GTF75_11840	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GTF75_11845	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GTF75_11855	ENOG4105DFP	Integrase
GTF75_11860	ENOG4105D58	Diguanylate phosphodiesterase
GTF75_11865	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_11875	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GTF75_11885	ENOG4108YGG	dna repair protein
GTF75_11915	ENOG4105DR5	peptidase
GTF75_11970	ENOG4105CH5	extracellular solute-binding protein, family 7
GTF75_11975	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GTF75_11980	ENOG410804X	Transcriptional regulator
GTF75_11985	ENOG4105CA9	Pyruvate kinase
GTF75_11990	ENOG4105MPN	Membrane
GTF75_12000	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
GTF75_12005	ENOG4105D64	Mechanosensitive ion channel
GTF75_12010	ENOG4105D2N	Aldolase
GTF75_12015	ENOG4105BZA	Phosphoglycerate kinase
GTF75_12020	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GTF75_12025	ENOG4105D05	Receptor
GTF75_12030	ENOG4108R4R	Iron-regulated virulence regulatory protein
GTF75_12035	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GTF75_12040	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GTF75_12050	ENOG4105RWS	endonuclease I
GTF75_12055	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GTF75_12060	ENOG4105D7Z	glutathione synthase
GTF75_12065	ENOG4108UJU	UPF0301 protein
GTF75_12070	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GTF75_12075	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GTF75_12085	ENOG4105CZX	twitching motility protein
GTF75_12090	ENOG4105CZX	twitching motility protein
GTF75_12095	ENOG4105DFA	alanine racemase domain protein
GTF75_12100	ENOG4105II7	pyrroline-5-carboxylate reductase
GTF75_12105	ENOG4108VIA	integral membrane protein
GTF75_12110	ENOG4105VZ9	UPF0235 protein
GTF75_12120	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GTF75_12125	ENOG4105CSA	Coproporphyrinogen iii oxidase
GTF75_12130	ENOG4105CSV	Glutaminase
GTF75_12140	ENOG4105CEN	a g-specific adenine glycosylase
GTF75_12145	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
GTF75_12150	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
GTF75_12205	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
GTF75_12210	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
GTF75_12215	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GTF75_12220	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GTF75_12225	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GTF75_12230	ENOG4105NWN	ApaG protein
GTF75_12235	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GTF75_12245	ENOG4107XM3	UPF0442 protein
GTF75_12250	ENOG4105DWK	Membrane
GTF75_12255	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GTF75_12260	ENOG4105K46	50S ribosomal protein l27
GTF75_12265	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GTF75_12270	ENOG4105EAH	synthase
GTF75_12280	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GTF75_12285	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
GTF75_12290	ENOG4105H1G	trap transporter solute receptor taxi family
GTF75_12300	ENOG41081QV	Universal stress protein
GTF75_12320	ENOG4105CEU	Arginine dihydrolase
GTF75_12325	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GTF75_12335	ENOG4105QD6	exported protein
GTF75_12340	ENOG4105C03	ribonuclease
GTF75_12345	ENOG4108Z03	MAF-like protein
GTF75_12350	ENOG4105VQ7	Rod shape-determining protein MreD
GTF75_12355	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
GTF75_12395	ENOG4105X0D	Fimbrial protein
GTF75_12405	ENOG4105D7Q	type ii secretion system
GTF75_12410	ENOG4107QHF	type ii secretion system protein e
GTF75_12425	ENOG4105E4G	Type IV pilus
GTF75_12445	ENOG41062P1	Diguanylate cyclase phosphodiesterase
GTF75_12450	ENOG4108UUM	single-stranded DNA-binding protein
GTF75_12455	ENOG41086KC	Transcriptional regulator
GTF75_12460	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GTF75_12465	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GTF75_12475	ENOG4105C5R	Aminotransferase
GTF75_12480	ENOG4105CFH	Aspartokinase
GTF75_12485	ENOG4105C3R	Methionine synthase
GTF75_12490	ENOG4105EEQ	Na H antiporter
GTF75_12555	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
GTF75_12565	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GTF75_12585	ENOG4105P4Z	Phage shock protein G
GTF75_12590	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GTF75_12595	ENOG4105MYN	Zinc uptake regulation protein
GTF75_12615	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
GTF75_12620	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GTF75_12625	ENOG4105CDU	Replicative dna helicase
GTF75_12635	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GTF75_12640	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GTF75_12645	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
GTF75_12650	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GTF75_12655	ENOG4108UQY	Iron-storage protein
GTF75_12660	ENOG4105W53	bacterioferritin-associated ferredoxin
GTF75_12665	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GTF75_12670	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GTF75_12675	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GTF75_12690	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
GTF75_12695	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
GTF75_12700	ENOG4105WWK	YheO domain protein
GTF75_12705	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GTF75_12715	ENOG41069P5	Protein slyX homolog
GTF75_12725	ENOG4105EPW	hflc protein
GTF75_12730	ENOG4107QJR	hflk protein
GTF75_12735	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GTF75_12740	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GTF75_12745	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GTF75_12750	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GTF75_12755	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GTF75_12760	ENOG4105K8N	protein family UPF0079, ATPase
GTF75_12765	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GTF75_12810	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GTF75_12815	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GTF75_12820	ENOG4105DJ4	phosphatidylserine decarboxylase
GTF75_12825	ENOG4105C8P	)-transporter
GTF75_12835	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GTF75_12840	ENOG41063SB	peptidase
GTF75_12850	ENOG41062JF	Transcriptional regulator
GTF75_12855	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GTF75_12860	ENOG4105E09	nadh pyrophosphatase
GTF75_12865	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
GTF75_12870	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GTF75_12875	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GTF75_12880	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GTF75_12885	ENOG4108VZM	50s ribosomal protein L10
GTF75_12895	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GTF75_12900	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GTF75_12905	ENOG4105PM1	preprotein translocase subunit SecE
GTF75_12910	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GTF75_12935	ENOG4105CS9	pantothenic acid kinase
GTF75_12940	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GTF75_12945	ENOG4105D4A	Cell wall formation (By similarity)
GTF75_12955	ENOG4105JIM	Phosphatidylserine synthase
GTF75_12990	ENOG4107QK7	reductase
GTF75_13000	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GTF75_13010	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GTF75_13020	ENOG4105C1J	atp-dependent rna helicase
GTF75_13025	ENOG4105C9X	ppx gppa phosphatase
GTF75_13030	ENOG4105BZU	Histidine kinase
GTF75_13035	ENOG4105D8G	Major Facilitator superfamily
GTF75_13050	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GTF75_13055	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GTF75_13060	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GTF75_13065	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GTF75_13070	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GTF75_13075	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GTF75_13080	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
GTF75_13085	ENOG4105DIQ	Transcriptional regulator
GTF75_13090	ENOG4105C01	Dihydroxy-acid dehydratase
GTF75_13095	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
GTF75_13100	ENOG4105C6Z	Gluconate
GTF75_13105	ENOG4108UHU	Aldolase
GTF75_13110	ENOG4105E0K	tonB-dependent siderophore receptor
GTF75_13125	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_13130	ENOG4105CXN	decarboxylase
GTF75_13135	ENOG4105D5Q	Arginine ornithine antiporter
GTF75_13140	ENOG4108M3R	transcriptional activator CadC
GTF75_13145	ENOG4105W1Y	Transcriptional regulator
GTF75_13160	ENOG4105C12	Phosphoribosylglycinamide synthetase
GTF75_13170	ENOG4105K70	DNA-binding protein
GTF75_13180	ENOG4105DKQ	ROK family
GTF75_13185	ENOG4105EIP	mannose-6-phosphate isomerase
GTF75_13190	ENOG4105R2J	Conserved Protein
GTF75_13195	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
GTF75_13200	ENOG4108RG0	uracil-dna glycosylase
GTF75_13205	ENOG4105CUY	Mechanosensitive ion channel
GTF75_13210	ENOG4105CY0	Metallo-Beta-Lactamase
GTF75_13215	ENOG4105D3Q	Sugar transferase
GTF75_13250	ENOG4108UT6	Transferase hexapeptide repeat containing protein
GTF75_13260	ENOG4105C0A	alcohol dehydrogenase
GTF75_13265	ENOG4105CEY	Amp-dependent synthetase and ligase
GTF75_13275	ENOG4105EY8	ABC transporter
GTF75_13290	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GTF75_13295	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
GTF75_13300	ENOG4107QKV	phosphomannomutase
GTF75_13305	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
GTF75_13310	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GTF75_13315	ENOG4107T94	Endo-14-beta-xylanase
GTF75_13330	ENOG4105XA0	heptosyltransferase ii
GTF75_13340	ENOG4108ST3	glycosyltransferase
GTF75_13345	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GTF75_13375	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
GTF75_13380	ENOG4105DKP	glycosyl transferase, family 9
GTF75_13385	ENOG4106WTF	Glycosyl transferase, family 2
GTF75_13390	ENOG4105M5K	heptosyltransferase
GTF75_13395	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GTF75_13400	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GTF75_13410	ENOG4105W0E	50S ribosomal protein L33
GTF75_13415	ENOG4105KDC	50s ribosomal protein l28
GTF75_13420	ENOG4105W5Q	DNA repair protein (RadC
GTF75_13425	ENOG4108NVR	Methyl-accepting chemotaxis
GTF75_13430	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GTF75_13440	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
GTF75_13445	ENOG4105D1S	lipid A biosynthesis
GTF75_13450	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
GTF75_13455	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GTF75_13460	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GTF75_13465	ENOG4105DSJ	YicC domain protein
GTF75_13470	ENOG4108TEB	UPF0114 protein
GTF75_13475	ENOG4105C5Y	PTS System
GTF75_13480	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GTF75_13485	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
GTF75_13490	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
GTF75_13495	ENOG4105J76	Periplasmic binding protein
GTF75_13500	ENOG4105E0A	ABC, transporter
GTF75_13505	ENOG4105E0K	tonB-dependent siderophore receptor
GTF75_13510	ENOG4105BZ1	(ABC) transporter
GTF75_13525	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GTF75_13530	ENOG4105FR1	rard protein
GTF75_13540	ENOG4108DMH	HTH_ARAC
GTF75_13545	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
GTF75_13550	ENOG4105C4R	Atp-dependent dna helicase
GTF75_13555	ENOG4105DGW	oligopeptidase A
GTF75_13560	ENOG4105D6S	protein involved in catabolism of external DNA
GTF75_13565	ENOG4105DC8	reductase
GTF75_13600	ENOG4108ZXE	
GTF75_13630	ENOG4108UK2	deaminase
GTF75_13640	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GTF75_13645	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GTF75_13650	ENOG4105DEF	Extracellular solute-binding protein, family 5
GTF75_13690	ENOG4105MPD	Cytochrome
GTF75_13695	ENOG4105C4R	Atp-dependent dna helicase
GTF75_13700	ENOG4105Y7M	Transcriptional regulator, TetR family
GTF75_13705	ENOG410624X	efflux transporter, rnd family, mfp subunit
GTF75_13710	ENOG4105BZS	acriflavin resistance protein
GTF75_13715	ENOG4105W0Z	cytoplasmic protein
GTF75_13720	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GTF75_13725	ENOG4105EMY	transcriptional regulator
GTF75_13770	ENOG4108RR8	protoporphyrinogen oxidase
GTF75_13775	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GTF75_13780	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GTF75_13790	ENOG4105CHU	acetyl-coa acetyltransferase
GTF75_13795	ENOG4105F52	Transcriptional regulator
GTF75_13800	ENOG4105CZQ	inner membrane transport protein YdhC
GTF75_13805	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GTF75_13810	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GTF75_13815	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GTF75_13820	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GTF75_13825	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GTF75_13830	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GTF75_13835	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GTF75_13845	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GTF75_13850	ENOG410684E	atp synthase
GTF75_13855	ENOG4105FA0	parb-like partition protein
GTF75_13860	ENOG4107QJE	Chromosome Partitioning Protein
GTF75_13870	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GTF75_13875	ENOG4105QTB	Flavodoxin
GTF75_13880	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GTF75_13885	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GTF75_13895	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GTF75_13910	ENOG4105E5Q	amino acid AbC transporter
GTF75_13915	ENOG4105EAB	amino acid AbC transporter
GTF75_13920	ENOG4106RMF	ParB family
GTF75_13950	ENOG4105CDY	transcriptional regulatory protein
GTF75_13955	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GTF75_13960	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_13965	ENOG4108YYI	Protein of unknown function (DUF2810)
GTF75_13970	ENOG41061ZR	Transcriptional regulator
GTF75_13975	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
GTF75_13980	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
GTF75_13985	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GTF75_13990	ENOG4108WC9	type VI secretion system effector, hcp1 family
GTF75_13995	ENOG4105CS6	Rhs element vgr protein
GTF75_14020	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GTF75_14030	ENOG4105C8P	)-transporter
GTF75_14035	ENOG4108Q67	UPF0319 protein
GTF75_14055	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_14075	ENOG4105EYK	Phosphatidylglycerophosphatase B
GTF75_14080	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
GTF75_14105	ENOG4105D6U	Sodium Glutamate Symporter
GTF75_14110	ENOG4105YE1	PilZ domain
GTF75_14125	ENOG4105EFX	secretion protein, HlyD family
GTF75_14130	ENOG4105KK7	inner membrane protein YiaW
GTF75_14135	ENOG4106TD9	Diguanylate cyclase
GTF75_14150	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GTF75_14155	ENOG4107SEY	Conserved Protein
GTF75_14165	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GTF75_14170	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
GTF75_14180	ENOG4105C1J	atp-dependent rna helicase
GTF75_14215	ENOG4105CVA	phosphate
GTF75_14220	ENOG4105C8U	phosphate abc transporter
GTF75_14225	ENOG4105E2Z	phosphate ABC transporter (Permease
GTF75_14230	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GTF75_14235	ENOG4105BZU	Histidine kinase
GTF75_14245	ENOG4105DWD	nucleoside recognition domain protein
GTF75_14250	ENOG4105CHH	sulfate transporter
GTF75_14260	ENOG4105DR5	peptidase
GTF75_14265	ENOG4105BZU	Histidine kinase
GTF75_14270	ENOG4105EQ2	LysR family Transcriptional regulator
GTF75_14275	ENOG4105E5M	Multidrug resistance protein D
GTF75_14280	ENOG4108Z4X	TRANSCRIPTIONal
GTF75_14295	ENOG4105CK2	sodium dicarboxylate symporter
GTF75_14335	ENOG4107RH7	Nicotinate phosphoribosyltransferase
GTF75_14340	ENOG4105D9R	oxidoreductase
GTF75_14350	ENOG4105BZU	Histidine kinase
GTF75_14355	ENOG4107VXZ	Hydrolase
GTF75_14365	ENOG4105D3G	Pseudouridine synthase
GTF75_14425	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GTF75_14430	ENOG4108JUB	Transcriptional regulator
GTF75_14455	ENOG4105CS6	Rhs element vgr protein
GTF75_14470	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
GTF75_14475	ENOG4105C2J	ABC transporter
GTF75_14480	ENOG4105CNN	ABC, transporter
GTF75_14485	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GTF75_14490	ENOG4108RVA	ribokinase
GTF75_14495	ENOG4105ETE	Transcriptional regulator (LacI family
GTF75_14500	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
GTF75_14505	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
GTF75_14510	ENOG4108I5U	Uridine phosphorylase
GTF75_14520	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
GTF75_14525	ENOG4105CXY	transporter
GTF75_14540	ENOG4105CQZ	Histidine kinase
GTF75_14545	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GTF75_14560	ENOG4105D5U	fad dependent oxidoreductase
GTF75_14570	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GTF75_14580	ENOG4105KJM	monovalent cation h antiporter subunit g
GTF75_14585	ENOG41080TA	Multiple resistance and ph regulation protein f
GTF75_14590	ENOG4105SC1	monovalent cation H antiporter subunit E
GTF75_14595	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GTF75_14600	ENOG4105MKQ	Monovalent cation H antiporter subunit C
GTF75_14605	ENOG4105D65	subunit l
GTF75_14615	ENOG4105Q9Y	Universal stress protein
GTF75_14620	ENOG4105CIC	tryptophan-specific transport protein
GTF75_14635	ENOG4105VRT	cytoplasmic protein
GTF75_14645	ENOG4105BZU	Histidine kinase
GTF75_14650	ENOG4105VEQ	Cold shock protein
GTF75_14685	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GTF75_14690	ENOG41069D7	Methyl-accepting chemotaxis
GTF75_14705	ENOG4105D9N	nucleoside
GTF75_14710	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GTF75_14720	ENOG4108JUA	Transcriptional regulator
GTF75_14725	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GTF75_14730	ENOG4105VEQ	Cold shock protein
GTF75_14750	ENOG4108UNF	response regulator
GTF75_14760	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GTF75_14765	ENOG4105C5I	Dehydrogenase
GTF75_14785	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GTF75_14810	ENOG4108RS6	transposase
GTF75_14825	ENOG4105C1J	atp-dependent rna helicase
GTF75_14830	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GTF75_14835	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
GTF75_14840	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GTF75_14845	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GTF75_14850	ENOG4105BZU	Histidine kinase
GTF75_14860	ENOG4107S6Z	Na H antiporter
GTF75_14865	ENOG4105E5M	Multidrug resistance protein D
GTF75_14875	ENOG4105BZU	Histidine kinase
GTF75_14880	ENOG4105KUU	lipolytic protein G-D-S-L family
GTF75_14885	ENOG4106M3D	hemolysin
GTF75_14890	ENOG4108N3W	hemolysin secretion protein
GTF75_14895	ENOG4107IFA	Lipase (EC 3.1.1.3)
GTF75_14920	ENOG4105DHS	permease protein
GTF75_14925	ENOG4105CM4	permease protein
GTF75_14930	ENOG4108IPW	abc transporter atp-binding protein
GTF75_14950	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GTF75_14970	ENOG4105ETX	regulatoR
GTF75_14980	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
GTF75_14990	ENOG410667J	hydrolase
GTF75_15020	ENOG4105DS1	cytochrome b561
GTF75_15050	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GTF75_15055	ENOG4105BZU	Histidine kinase
GTF75_15080	ENOG4107QVI	Methyltransferase, type 11
GTF75_15095	ENOG4105C2C	drug resistance transporter, Bcr CflA
GTF75_15100	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_15110	ENOG4105DZ1	carboxypeptidase
GTF75_15130	ENOG4108RS6	transposase
GTF75_15140	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GTF75_15145	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GTF75_15150	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GTF75_15160	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GTF75_15170	ENOG4105F2I	Transposase
GTF75_15200	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GTF75_15205	ENOG41082NX	50s ribosomal protein l35
GTF75_15210	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GTF75_15265	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GTF75_15300	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GTF75_15345	ENOG4105D9U	N-acetyltransferase
GTF75_15350	ENOG4105QNF	Outer membrane lipoprotein
GTF75_15380	ENOG4105VXN	addiction module toxin, RelE StbE family
GTF75_15405	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
GTF75_15485	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
GTF75_15505	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
GTF75_15545	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
GTF75_15565	ENOG4105QNF	Outer membrane lipoprotein
GTF75_15580	ENOG4105YGK	Pfam:UPF0157
GTF75_15590	ENOG4105N14	lysine exporter protein LysE YggA
GTF75_15775	ENOG41080ET	plasmid maintenance system killer protein
GTF75_15780	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
GTF75_15800	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
GTF75_15825	ENOG4105QNF	Outer membrane lipoprotein
GTF75_15930	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
GTF75_15970	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
GTF75_15975	ENOG4105W08	virulence gene repressor rsal
GTF75_15990	ENOG4105F2I	Transposase
GTF75_16015	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
GTF75_16105	ENOG4108RS6	transposase
GTF75_16170	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
GTF75_16190	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
GTF75_16195	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
GTF75_16200	ENOG4105CGF	Aromatic amino acid aminotransferase
GTF75_16205	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GTF75_16210	ENOG4105DM4	PTS System
GTF75_16215	ENOG4105DE4	1-phosphofructokinase
GTF75_16220	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
GTF75_16225	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
GTF75_16230	ENOG4107RFY	SbcCD D subunit
GTF75_16235	ENOG4105EYH	Exonuclease
GTF75_16240	ENOG4108MGY	Histidine kinase
GTF75_16245	ENOG4107KBT	8-Amino-7-oxononanoate synthase
GTF75_16260	ENOG4105CKI	cobalamin synthesis protein
GTF75_16265	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
GTF75_16275	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
GTF75_16280	ENOG4105C08	Histidine kinase
GTF75_16285	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
GTF75_16290	ENOG410607N	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity)
GTF75_16295	ENOG4108RHM	integral membrane protein
GTF75_16305	ENOG4105EPM	Diguanylate phosphodiesterase
GTF75_16315	ENOG4105DS1	cytochrome b561
GTF75_16325	ENOG4105TMB	Formate nitrite transporter
GTF75_16330	ENOG4105DUM	transcriptional regulator, lysR family
GTF75_16335	ENOG4108UQ5	membrane protein YcdZ
GTF75_16340	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
GTF75_16345	ENOG4105CGH	5'-nucleotidase
GTF75_16350	ENOG4105DU1	integral membrane protein, terc
GTF75_16360	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
GTF75_16390	ENOG4105BZU	Histidine kinase
GTF75_16400	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GTF75_16410	ENOG4105BZU	Histidine kinase
GTF75_16425	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GTF75_16430	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GTF75_16440	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GTF75_16460	ENOG4108ZJT	translation initiation factor, Sui1
GTF75_16480	ENOG4105CD5	CoA-binding domain protein
GTF75_16485	ENOG4105CWB	LysR family transcriptional Regulator
GTF75_16505	ENOG4105KA0	thioesterase Superfamily protein
GTF75_16525	ENOG4105CYM	Glutathione S-transferase
GTF75_16540	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GTF75_16545	ENOG4108JQ5	ABC transporter
GTF75_16550	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
GTF75_16555	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
GTF75_16560	ENOG4105E43	Extracellular solute-binding protein, family 5
GTF75_16585	ENOG4105DUX	Transporter
GTF75_16600	ENOG4107RCV	ABC transporter, permease
GTF75_16615	ENOG4107STF	Involved in phosphonate degradation (By similarity)
GTF75_16620	ENOG4108JPW	Aminotransferase
GTF75_16625	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
GTF75_16630	ENOG4105NXH	GreA GreB family elongation factor
GTF75_16635	ENOG4105PAD	Hydrolase
GTF75_16645	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
GTF75_16650	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GTF75_16655	ENOG4105CKU	formyltetrahydrofolate synthetase
GTF75_16660	ENOG4105E0X	reductase
GTF75_16665	ENOG4105EUJ	GTP cyclohydrolase i
GTF75_16670	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GTF75_16675	ENOG4105D06	uba thif-type nad fad binding protein
GTF75_16685	ENOG4105KHC	sulfurtransferase
GTF75_16690	ENOG4107RHR	regulatoR
GTF75_16700	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GTF75_16725	ENOG4108M3J	Dehydrogenase
GTF75_16740	ENOG4105RA2	Membrane
GTF75_16750	ENOG4105ETT	transcriptional Regulator, LysR family
GTF75_16755	ENOG41067V3	Antibiotic biosynthesis monooxygenase
GTF75_16795	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
GTF75_16840	ENOG4105C5Y	PTS System
GTF75_16845	ENOG4105ETE	Transcriptional regulator (LacI family
GTF75_16850	ENOG4107R3K	hydrolase
GTF75_16855	ENOG4105D7K	pfkb domain protein
GTF75_16860	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GTF75_16865	ENOG4108NVR	Methyl-accepting chemotaxis
GTF75_16870	ENOG4108ZG0	Ompa motb domain protein
GTF75_16875	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GTF75_16880	ENOG4107VXZ	Hydrolase
GTF75_16885	ENOG4108N3W	hemolysin secretion protein
GTF75_16890	ENOG4105CEE	C4-dicarboxylate transporter
GTF75_16895	ENOG4105EJQ	L-serine dehydratase
GTF75_16915	ENOG4105ETE	Transcriptional regulator (LacI family
GTF75_16920	ENOG4105WH1	Two component transcriptional regulator luxr family
GTF75_16925	ENOG4105BZU	Histidine kinase
GTF75_16940	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GTF75_16960	ENOG4105DHT	Metal Dependent Phosphohydrolase
GTF75_16965	ENOG4108KX4	response regulator
GTF75_16970	ENOG4105BZU	Histidine kinase
GTF75_16975	ENOG4105CXY	transporter
GTF75_16980	ENOG4105C4Y	ABC transporter
GTF75_16985	ENOG4107RCV	ABC transporter, permease
GTF75_16990	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GTF75_16995	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
GTF75_17005	ENOG4105CHU	acetyl-coa acetyltransferase
GTF75_17015	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GTF75_17020	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GTF75_17035	ENOG4105BZU	Histidine kinase
GTF75_17040	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GTF75_17050	ENOG4108I6A	alcohol dehydrogenase
GTF75_17060	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
GTF75_17070	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
GTF75_17075	ENOG4105CXY	transporter
GTF75_17080	ENOG4105CA9	Pyruvate kinase
GTF75_17085	ENOG4105BZU	Histidine kinase
GTF75_17090	ENOG4108SV3	Tmao reductase system periplasmic protein tort
GTF75_17095	ENOG4108Z5K	methylglyoxal synthase
GTF75_17100	ENOG4108RWI	nicotinamidase
GTF75_17105	ENOG41080IJ	Diacylglycerol kinase
GTF75_17120	ENOG41088T4	Helicase IV
GTF75_17125	ENOG4105EM2	membrane
GTF75_17155	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
GTF75_17160	ENOG4105E0C	molybdate abc transporter
GTF75_17165	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GTF75_17170	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
GTF75_17210	ENOG4105BZU	Histidine kinase
GTF75_17215	ENOG4108QGH	periplasmic
GTF75_17225	ENOG41082IR	Excinuclease ABC C subunit domain protein
GTF75_17240	ENOG41090HJ	UPF0265 protein
GTF75_17250	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GTF75_17255	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GTF75_17260	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
GTF75_17265	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
GTF75_17270	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GTF75_17275	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GTF75_17280	ENOG4105K63	Thioredoxin
GTF75_17310	ENOG4105DUM	transcriptional regulator, lysR family
GTF75_17315	ENOG4105DMR	ABC, transporter
GTF75_17320	ENOG4105GBT	ABC transporter
GTF75_17325	ENOG4106PMH	Extracellular solute-binding protein family 3
GTF75_17330	ENOG4105E5Z	arginine transporter ATP-binding subunit
GTF75_17340	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
GTF75_17350	ENOG4108YZ4	nudix hydrolase
GTF75_17355	ENOG4105C5W	Aldolase
GTF75_17360	ENOG4106RE7	Cytochrome
GTF75_17365	ENOG4107XI7	Tetr family transcriptional regulator
GTF75_17370	ENOG4105C1J	atp-dependent rna helicase
GTF75_17375	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
GTF75_17380	ENOG4105E0U	tyrosine-specific transport protein
GTF75_17385	ENOG4108N3W	hemolysin secretion protein
GTF75_17390	ENOG4105CMR	udp-glucose 4-epimerase
GTF75_17395	ENOG4105E7W	lamb ycsf family protein
GTF75_17405	ENOG4107R7A	Allophanate hydrolase subunit 2
GTF75_17415	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GTF75_17420	ENOG4105CV6	ABC transporter, permease
GTF75_17425	ENOG4108I0Y	(ABC) transporter
GTF75_17435	ENOG4105RKW	reductase (By
GTF75_17450	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GTF75_17490	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GTF75_17505	ENOG4107RE1	Inosine-guanosine kinase
GTF75_17510	ENOG4105E0M	Sulfatase
GTF75_17520	ENOG4105C1J	atp-dependent rna helicase
GTF75_17535	ENOG4105CVA	phosphate
GTF75_17545	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
GTF75_17550	ENOG4108M1A	Chitin-binding protein
GTF75_17555	ENOG4105D4Y	metalloprotease
GTF75_17565	ENOG4105CYW	agmatinase
GTF75_17570	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
GTF75_17580	ENOG4105CJW	magnesium transporter
GTF75_17585	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GTF75_17590	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GTF75_17600	ENOG4105CZK	Aspartate kinase
GTF75_17605	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
GTF75_17610	ENOG4108JPW	Aminotransferase
GTF75_17615	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
GTF75_17625	ENOG4105MIR	Phenylalanine 4-monooxygenase
GTF75_17630	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GTF75_17645	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GTF75_17650	ENOG4105EGI	Transcriptional regulator
GTF75_17670	ENOG4105C37	(CBS) domain
GTF75_17675	ENOG4108UKZ	OsmC family
GTF75_17680	ENOG4107YWA	deoxycytidylate deaminase
GTF75_17700	ENOG4105DVH	amino acid
GTF75_17705	ENOG4106TD9	Diguanylate cyclase
GTF75_17715	ENOG4108VAC	response regulator
GTF75_17720	ENOG4108HRK	Histidine kinase
GTF75_17735	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GTF75_17740	ENOG4105C19	ABC transporter
GTF75_17750	ENOG4107RGM	aldo keto reductase
GTF75_17755	ENOG4107T9C	Alpha amylase catalytic region
GTF75_17765	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GTF75_17770	ENOG4108M0H	Extracellular lipase
GTF75_17775	ENOG4107SDU	Methyl-accepting chemotaxis
GTF75_17780	ENOG4105D4Y	metalloprotease
GTF75_17790	ENOG4105EIF	outer membrane protein W
GTF75_17800	ENOG41061WM	D-Alanyl-D-Alanine
GTF75_17805	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GTF75_17810	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GTF75_17815	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GTF75_17830	ENOG4105BZC	d-serine deaminase
GTF75_17835	ENOG4105W8I	Transcriptional regulator
GTF75_17880	ENOG4105CPQ	Dehydrogenase
GTF75_17885	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GTF75_17900	ENOG4105EXG	Transcriptional regulator
GTF75_17905	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
GTF75_17925	ENOG4107SSZ	Phosphatase
GTF75_17930	ENOG4105DHT	Metal Dependent Phosphohydrolase
GTF75_17935	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GTF75_17940	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
GTF75_17945	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GTF75_17970	ENOG4105BZW	Glycerate kinase
GTF75_17975	ENOG4105C6Z	Gluconate
GTF75_17980	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
GTF75_17985	ENOG4108NVR	Methyl-accepting chemotaxis
GTF75_17990	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
GTF75_17995	ENOG41090JE	Utilization Protein
GTF75_18000	ENOG4105D4P	Coproporphyrinogen iii oxidase
GTF75_18005	ENOG4105WQ5	TonB family
GTF75_18010	ENOG41090AP	transport protein
GTF75_18015	ENOG4106GFD	transport protein
GTF75_18020	ENOG4107R4I	Periplasmic binding protein
GTF75_18025	ENOG4105EHG	Permease protein
GTF75_18030	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
GTF75_18060	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_18065	ENOG4105QVC	MOSC domain-containing protein
GTF75_18065	ENOG4105QVC	MOSC domain-containing protein
GTF75_18070	ENOG4105EKE	dihydroorotase
GTF75_18080	ENOG4105KAF	membrAne
GTF75_18090	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
GTF75_18095	ENOG4105CKW	Inner membrane protein yedI
GTF75_18100	ENOG4108ESY	Metal dependent phosphohydrolase
GTF75_18105	ENOG4105VEQ	Cold shock protein
GTF75_18120	ENOG4105EQD	regulatoR
GTF75_18130	ENOG4105BZU	Histidine kinase
GTF75_18135	ENOG4105E98	transcriptional regulator DeoR family
GTF75_18150	ENOG4105EG2	ABC transporter, permease
GTF75_18155	ENOG4105D56	permease protein
GTF75_18160	ENOG4107FKK	extracellular solute-binding protein family 1
GTF75_18165	ENOG4108IJ9	(ABC) transporter
GTF75_18170	ENOG4108HK0	-acetyltransferase
GTF75_18185	ENOG4105K8R	UPF0145 protein
GTF75_18190	ENOG41086KC	Transcriptional regulator
GTF75_18195	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
GTF75_18205	ENOG4105K56	Transcriptional regulator
GTF75_18210	ENOG4106TD9	Diguanylate cyclase
GTF75_18225	ENOG4105BZU	Histidine kinase
GTF75_18245	ENOG4105ETT	transcriptional Regulator, LysR family
GTF75_18250	ENOG4108K0B	C-di-gmp phosphodiesterase
GTF75_18260	ENOG4105EUB	pirin domain protein
GTF75_18265	ENOG4105NBK	UPF0345 protein
GTF75_18275	ENOG4105E5W	Transporter
GTF75_18280	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_18285	ENOG4105DAN	ATP-dependent protease
GTF75_18295	ENOG4108JQ5	ABC transporter
GTF75_18300	ENOG4105E89	ABC transporter
GTF75_18305	ENOG4107SDU	Methyl-accepting chemotaxis
GTF75_18320	ENOG4105CC0	LysR family Transcriptional regulator
GTF75_18330	ENOG4105DAA	L-lactate
GTF75_18345	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
GTF75_18355	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GTF75_18365	ENOG4105C1J	atp-dependent rna helicase
GTF75_18370	ENOG4105CR8	Transcriptional regulator
GTF75_18380	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GTF75_18390	ENOG4105BZ1	(ABC) transporter
GTF75_18400	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GTF75_18410	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
GTF75_18435	ENOG4105K56	Transcriptional regulator
GTF75_18440	ENOG4108ZHJ	Organic hydroperoxide resistance protein
GTF75_18450	ENOG4108SXK	Transporter Drug Metabolite Exporter family
GTF75_18455	ENOG4105VW4	glutaredoxin 3
GTF75_18460	ENOG4108P2H	Inner membrane protein YjiG
GTF75_18465	ENOG41074DU	domain protein
GTF75_18470	ENOG4105DN9	Na H antiporter
GTF75_18480	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GTF75_18485	ENOG4105D03	DNA-3-methyladenine glycosylase II
GTF75_18490	ENOG4108VGI	doxx family
GTF75_18515	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GTF75_18525	ENOG4107W52	maltose operon periplasmic protein
GTF75_18530	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
GTF75_18545	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_18560	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_18570	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GTF75_18575	ENOG4105CDA	abc transporter atp-binding protein
GTF75_18585	ENOG4106TNF	Periplasmic binding protein
GTF75_18590	ENOG4105EZ7	amino acid ABC transporter
GTF75_18595	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
GTF75_18605	ENOG4105DR5	peptidase
GTF75_18610	ENOG4105CTS	PTS system mannitol-specific
GTF75_18615	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
GTF75_18620	ENOG4105E61	Mannitol repressor protein
GTF75_18625	ENOG4105EP9	oxidoreductase
GTF75_18655	ENOG4108RYK	Nad-dependent epimerase dehydratase
GTF75_18660	ENOG4105JQN	Transcriptional regulator
GTF75_18665	ENOG41069D7	Methyl-accepting chemotaxis
GTF75_18670	ENOG4105EMU	Dehydrogenase
GTF75_18675	ENOG4105JQN	Transcriptional regulator
GTF75_18695	ENOG4105D5Q	Arginine ornithine antiporter
GTF75_18700	ENOG4105CXN	decarboxylase
GTF75_18710	ENOG4107RGH	Aldehyde dehydrogenase
GTF75_18715	ENOG4105EW9	transcriptional regulator AsnC family
GTF75_18720	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_18730	ENOG4105CK7	Sodium proline symporter
GTF75_18740	ENOG4105C26	Dehydrogenase
GTF75_18755	ENOG4105E6M	Sulphatase-modifying factor protein
GTF75_18770	ENOG4107QZV	Type I secretion membrane fusion protein
GTF75_18785	ENOG4108JJA	ABC, transporter
GTF75_18795	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GTF75_18805	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_18810	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GTF75_18820	ENOG4105BZU	Histidine kinase
GTF75_18825	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF75_18830	ENOG4108V3W	Chemotaxis protein, CheW
GTF75_18835	ENOG4108V3W	Chemotaxis protein, CheW
GTF75_18840	ENOG4105CBS	Chea signal transduction histidine kinase
GTF75_18845	ENOG4108VYJ	response regulator receiver protein
GTF75_18860	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GTF75_18865	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GTF75_18870	ENOG4108JQ6	ABC transporter
GTF75_18875	ENOG4105DIJ	Phosphoethanolamine transferase
GTF75_18880	ENOG4105DHQ	Histidine kinase
GTF75_18885	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GTF75_18915	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
GTF75_18920	ENOG4107RUE	extracellular solute-binding protein family 1