locus-tag	class	description
Vch1786_I0001	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Vch1786_I0003	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Vch1786_I0004	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Vch1786_I0006	COG1489	DNA binding
Vch1786_I0009	COG1643	Atp-dependent helicase
Vch1786_I0010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Vch1786_I0011	COG1752	Esterase of the alpha-beta hydrolase superfamily
Vch1786_I0012	COG1049	propionate catabolic process, 2-methylcitrate cycle
Vch1786_I0013	COG3112	Uncharacterised protein family (UPF0231)
Vch1786_I0014	COG0347	Belongs to the P(II) protein family
Vch1786_I0015	COG0004	ammonium transporteR
Vch1786_I0016	COG1840	ABC-type Fe3 transport system, periplasmic component
Vch1786_I0018	COG3842	ATPase activity
Vch1786_I0022	COG2971	BadF BadG BcrA BcrD
Vch1786_I0024	COG4608	Belongs to the ABC transporter superfamily
Vch1786_I0025	COG0444	Belongs to the ABC transporter superfamily
Vch1786_I0026	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vch1786_I0027	COG0601	transmembrane transport
Vch1786_I0028	COG0747	negative chemotaxis
Vch1786_I0030	COG2813	Specifically methylates the guanine in position
Vch1786_I0031	COG0628	permease
Vch1786_I0033	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Vch1786_I0035	COG0316	Belongs to the HesB IscA family
Vch1786_I0038	COG0739	heme binding
Vch1786_I0039	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Vch1786_I0040	COG2027	D-alanyl-D-alanine carboxypeptidase
Vch1786_I0041	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vch1786_I0042	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Vch1786_I0043	COG1534	Rna-binding protein
Vch1786_I0044	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Vch1786_I0045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Vch1786_I0046	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Vch1786_I0047	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Vch1786_I0048	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Vch1786_I0051	COG0779	Required for maturation of 30S ribosomal subunits
Vch1786_I0052	COG0195	Participates in both transcription termination and antitermination
Vch1786_I0053	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Vch1786_I0054	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Vch1786_I0055	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Vch1786_I0056	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Vch1786_I0057	COG1185	polyribonucleotide nucleotidyltransferase activity
Vch1786_I0058	COG4785	May be involved in cell division
Vch1786_I0065	COG3153	acetyltransferase
Vch1786_I0069	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Vch1786_I0088	COG3328	transposase activity
Vch1786_I0091	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Vch1786_I0117	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vch1786_I0120	COG0681	Belongs to the peptidase S26 family
Vch1786_I0128	COG2356	endonuclease I
Vch1786_I0131	COG0629	single-stranded DNA binding
Vch1786_I0135	COG0714	Associated with various cellular activities
Vch1786_I0140	COG2003	Belongs to the UPF0758 family
Vch1786_I0161	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Vch1786_I0162	COG0513	Belongs to the DEAD box helicase family
Vch1786_I0163	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Vch1786_I0165	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Vch1786_I0166	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Vch1786_I0167	COG2204	response regulator
Vch1786_I0170	COG0667	Aldo Keto reductase
Vch1786_I0171	COG3066	DNA modification
Vch1786_I0175	COG0494	nUDIX hydrolase
Vch1786_I0176	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
Vch1786_I0177	COG0730	response to heat
Vch1786_I0178	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Vch1786_I0179	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Vch1786_I0180	COG1283	sodium-dependent phosphate transmembrane transporter activity
Vch1786_I0181	COG0583	DNA-binding transcription factor activity
Vch1786_I0182	COG0640	Transcriptional regulator
Vch1786_I0183	COG0268	Binds directly to 16S ribosomal RNA
Vch1786_I0184	COG0728	peptidoglycan biosynthetic process
Vch1786_I0185	COG0196	riboflavin kinase activity
Vch1786_I0186	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Vch1786_I0187	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Vch1786_I0188	COG1047	Peptidyl-prolyl cis-trans
Vch1786_I0189	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Vch1786_I0191	COG1966	Carbon starvation protein
Vch1786_I0194	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Vch1786_I0195	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Vch1786_I0196	COG1472	Belongs to the glycosyl hydrolase 3 family
Vch1786_I0197	COG3279	Response regulator of the LytR AlgR family
Vch1786_I0198	COG3275	phosphorelay sensor kinase activity
Vch1786_I0199	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Vch1786_I0200	COG1605	Chorismate mutase
Vch1786_I0200	COG0287	Prephenate dehydrogenase
Vch1786_I0202	COG0488	(ABC) transporter
Vch1786_I0205	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
Vch1786_I0206	COG5001	Diguanylate cyclase
Vch1786_I0207	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Vch1786_I0208	COG1605	Chorismate mutase
Vch1786_I0208	COG0077	Prephenate dehydratase
Vch1786_I0209	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Vch1786_I0211	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vch1786_I0212	COG0564	pseudouridine synthase activity
Vch1786_I0214	COG0542	response to heat
Vch1786_I0224	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Vch1786_I0226	COG2974	May be involved in recombination
Vch1786_I0227	COG0745	RESPONSE REGULATOR receiver
Vch1786_I0228	COG5002	protein histidine kinase activity
Vch1786_I0230	COG0248	Ppx GppA phosphatase
Vch1786_I0231	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Vch1786_I0233	COG0581	inorganic phosphate transmembrane transporter activity
Vch1786_I0234	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Vch1786_I0237	COG3142	Participates in the control of copper homeostasis
Vch1786_I0238	COG0450	alkyl hydroperoxide reductase
Vch1786_I0239	COG0583	DNA-binding transcription factor activity
Vch1786_I0241	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Vch1786_I0244	COG0517	IMP dehydrogenase activity
Vch1786_I0246	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Vch1786_I0247	COG0343	queuine tRNA-ribosyltransferase activity
Vch1786_I0248	COG1862	Preprotein translocase
Vch1786_I0249	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vch1786_I0250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vch1786_I0251	COG0483	inositol monophosphate 1-phosphatase activity
Vch1786_I0253	COG1959	2 iron, 2 sulfur cluster binding
Vch1786_I0254	COG1104	cysteine desulfurase activity
Vch1786_I0255	COG0822	iron-sulfur transferase activity
Vch1786_I0257	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Vch1786_I0258	COG0443	Heat shock 70 kDa protein
Vch1786_I0259	COG0633	Ferredoxin
Vch1786_I0260	COG2975	iron-sulfur cluster assembly
Vch1786_I0261	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Vch1786_I0262	COG0105	UTP biosynthetic process
Vch1786_I0263	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Vch1786_I0265	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Vch1786_I0266	COG0124	histidyl-tRNA synthetase
Vch1786_I0267	COG2976	Protein conserved in bacteria
Vch1786_I0268	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vch1786_I0269	COG1160	GTP binding
Vch1786_I0272	COG1570	exodeoxyribonuclease VII activity
Vch1786_I0273	COG0516	GMP reductase activity
Vch1786_I0273	COG0517	IMP dehydrogenase activity
Vch1786_I0274	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Vch1786_I0274	COG0519	Catalyzes the synthesis of GMP from XMP
Vch1786_I0276	COG1584	GPR1 FUN34 yaaH family protein
Vch1786_I0277	COG3433	isochorismatase activity
Vch1786_I0277	COG1535	isochorismatase
Vch1786_I0278	COG1021	2,3-dihydroxybenzoate-AMP ligase
Vch1786_I0279	COG1169	isochorismate synthase
Vch1786_I0280	COG1028	Short-chain dehydrogenase reductase Sdr
Vch1786_I0282	COG4592	Periplasmic binding protein
Vch1786_I0283	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vch1786_I0284	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vch1786_I0285	COG1120	ATPase activity
Vch1786_I0287	COG0583	DNA-binding transcription factor activity
Vch1786_I0289	COG2015	COG2015, Alkyl sulfatase and related hydrolases
Vch1786_I0290	COG1115	amino acid carrier protein
Vch1786_I0292	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Vch1786_I0293	COG0583	DNA-binding transcription factor activity
Vch1786_I0296	COG4565	transcriptional regulatory protein
Vch1786_I0298	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
Vch1786_I0299	COG5016	pyruvate
Vch1786_I0299	COG0511	ligase activity, forming carbon-carbon bonds
Vch1786_I0300	COG3630	sodium ion export across plasma membrane
Vch1786_I0302	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
Vch1786_I0303	COG3052	prosthetic group binding
Vch1786_I0304	COG2301	Belongs to the HpcH HpaI aldolase family
Vch1786_I0305	COG3051	citrate lyase alpha subunit
Vch1786_I0306	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
Vch1786_I0307	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
Vch1786_I0309	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Vch1786_I0310	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Vch1786_I0312	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Vch1786_I0326	COG1012	belongs to the aldehyde dehydrogenase family
Vch1786_I0330	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Vch1786_I0331	COG0840	transmembrane signaling receptor activity
Vch1786_I0332	COG3710	Transcriptional regulator
Vch1786_I0334	COG2165	general secretion pathway protein
Vch1786_I0337	COG4796	Type ii and iii secretion system protein
Vch1786_I0341	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vch1786_I0342	COG1459	type II secretion system
Vch1786_I0344	COG2207	Transcriptional regulator
Vch1786_I0345	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Vch1786_I0348	COG0739	heme binding
Vch1786_I0350	COG3064	Membrane
Vch1786_I0352	COG0582	viral genome integration into host DNA
Vch1786_I0353	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Vch1786_I0354	COG2867	negative regulation of translational initiation
Vch1786_I0355	COG2914	Belongs to the UPF0125 (RnfH) family
Vch1786_I0356	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vch1786_I0357	COG0497	DNA recombination
Vch1786_I0358	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Vch1786_I0359	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Vch1786_I0361	COG0443	Heat shock 70 kDa protein
Vch1786_I0362	COG0484	heat shock protein binding
Vch1786_I0364	COG4968	Prepilin-type N-terminal cleavage methylation domain
Vch1786_I0369	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Vch1786_I0370	COG0590	tRNA wobble adenosine to inosine editing
Vch1786_I0372	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Vch1786_I0375	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Vch1786_I0375	COG0047	phosphoribosylformylglycinamidine synthase activity
Vch1786_I0376	COG1943	Transposase
Vch1786_I0381	COG0442	prolyl-tRNA aminoacylation
Vch1786_I0382	COG1720	tRNA m6t6A37 methyltransferase activity
Vch1786_I0384	COG0254	rRNA binding
Vch1786_I0385	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Vch1786_I0386	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Vch1786_I0387	COG1671	Belongs to the UPF0178 family
Vch1786_I0390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vch1786_I0393	COG3098	single-species biofilm formation
Vch1786_I0394	COG0564	pseudouridine synthase activity
Vch1786_I0395	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Vch1786_I0396	COG0142	geranyltranstransferase activity
Vch1786_I0397	COG1722	exodeoxyribonuclease VII activity
Vch1786_I0398	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Vch1786_I0400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Vch1786_I0400	COG0301	tRNA thio-modification
Vch1786_I0402	COG0583	DNA-binding transcription factor activity
Vch1786_I0403	COG2363	Small membrane protein
Vch1786_I0404	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Vch1786_I0405	COG1611	Belongs to the LOG family
Vch1786_I0406	COG3706	GGDEF domain
Vch1786_I0408	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Vch1786_I0408	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Vch1786_I0410	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
Vch1786_I0411	COG1464	Belongs to the NlpA lipoprotein family
Vch1786_I0412	COG2011	ABC-type metal ion transport system permease component
Vch1786_I0413	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Vch1786_I0414	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Vch1786_I0415	COG1609	Transcriptional regulator
Vch1786_I0416	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vch1786_I0416	COG1263	PTS System
Vch1786_I0417	COG0366	Alpha amylase catalytic
Vch1786_I0421	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vch1786_I0423	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Vch1786_I0424	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Vch1786_I0425	COG0110	maltose O-acetyltransferase activity
Vch1786_I0429	COG1045	serine acetyltransferase
Vch1786_I0431	COG0438	transferase activity, transferring glycosyl groups
Vch1786_I0433	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Vch1786_I0439	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Vch1786_I0441	COG1596	polysaccharide export
Vch1786_I0446	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Vch1786_I0448	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Vch1786_I0449	COG0321	lipoyl(octanoyl) transferase activity
Vch1786_I0450	COG2921	Belongs to the UPF0250 family
Vch1786_I0451	COG1686	Belongs to the peptidase S11 family
Vch1786_I0452	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Vch1786_I0453	COG0772	Belongs to the SEDS family
Vch1786_I0454	COG0768	penicillin binding
Vch1786_I0455	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Vch1786_I0456	COG0799	negative regulation of ribosome biogenesis
Vch1786_I0457	COG1466	dna polymerase III delta subunit
Vch1786_I0458	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
Vch1786_I0460	COG0495	leucyl-tRNA aminoacylation
Vch1786_I0461	COG2888	peptidyl-tyrosine sulfation
Vch1786_I0462	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Vch1786_I0463	COG4535	Mg2 and Co2 transporter CorC
Vch1786_I0464	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Vch1786_I0465	COG1702	phosphate starvation-inducible protein PhoH
Vch1786_I0466	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Vch1786_I0467	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vch1786_I0468	COG2190	(PTS) system
Vch1786_I0470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vch1786_I0472	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Vch1786_I0473	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
Vch1786_I0474	COG3115	cell septum assembly
Vch1786_I0475	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Vch1786_I0478	COG0789	Transcriptional regulator
Vch1786_I0479	COG0330	HflC and HflK could
Vch1786_I0480	COG3118	belongs to the thioredoxin family
Vch1786_I0482	COG0300	oxidoreductase activity
Vch1786_I0483	COG1090	epimerase
Vch1786_I0484	COG0622	Phosphoesterase
Vch1786_I0487	COG3710	Transcriptional regulator
Vch1786_I0488	COG0326	Molecular chaperone. Has ATPase activity
Vch1786_I0489	COG0563	adenylate kinase activity
Vch1786_I0490	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Vch1786_I0496	COG0367	asparagine synthase
Vch1786_I0497	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Vch1786_I0497	COG4651	solute:proton antiporter activity
Vch1786_I0498	COG1846	Transcriptional regulator
Vch1786_I0498	COG1940	carbohydrate kinase activity
Vch1786_I0499	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Vch1786_I0500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vch1786_I0500	COG1263	PTS System
Vch1786_I0500	COG2190	(PTS) system
Vch1786_I0502	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Vch1786_I0504	COG0101	tRNA pseudouridine synthase activity
Vch1786_I0505	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Vch1786_I0506	COG0285	dihydrofolate synthase activity
Vch1786_I0507	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
Vch1786_I0508	COG1286	toxin biosynthetic process
Vch1786_I0509	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Vch1786_I0510	COG2056	Na+-H+ antiporter family
Vch1786_I0511	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Vch1786_I0515	COG0346	lactoylglutathione lyase activity
Vch1786_I0516	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Vch1786_I0517	COG4660	Part of a membrane complex involved in electron transport
Vch1786_I0518	COG4659	FMN binding
Vch1786_I0519	COG4658	electron transport chain
Vch1786_I0520	COG4656	Part of a membrane complex involved in electron transport
Vch1786_I0521	COG2878	Part of a membrane complex involved in electron transport
Vch1786_I0522	COG4657	Part of a membrane complex involved in electron transport
Vch1786_I0524	COG0556	nucleotide-excision repair
Vch1786_I0525	COG2204	response regulator
Vch1786_I0526	COG2198	Histidine kinase
Vch1786_I0527	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Vch1786_I0528	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Vch1786_I0529	COG0521	Mo-molybdopterin cofactor biosynthetic process
Vch1786_I0530	COG0315	cyclic pyranopterin monophosphate synthase activity
Vch1786_I0531	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Vch1786_I0532	COG0314	molybdopterin synthase activity
Vch1786_I0533	COG2199	diguanylate cyclase activity
Vch1786_I0535	COG4109	DRTGG domain
Vch1786_I0537	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
Vch1786_I0539	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Vch1786_I0539	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Vch1786_I0540	COG0489	protein tyrosine kinase activity
Vch1786_I0541	COG0572	uridine kinase
Vch1786_I0542	COG2982	Protein involved in outer membrane biogenesis
Vch1786_I0543	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Vch1786_I0544	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
Vch1786_I0546	COG2067	long-chain fatty acid transport protein
Vch1786_I0549	COG0183	Belongs to the thiolase family
Vch1786_I0550	COG1250	3-hydroxyacyl-CoA dehydrogenase
Vch1786_I0550	COG1024	Enoyl-CoA hydratase
Vch1786_I0551	COG0778	Nitroreductase
Vch1786_I0552	COG0583	DNA-binding transcription factor activity
Vch1786_I0553	COG0745	RESPONSE REGULATOR receiver
Vch1786_I0555	COG2832	Protein of unknown function (DUF454)
Vch1786_I0556	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Vch1786_I0558	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Vch1786_I0559	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Vch1786_I0562	COG1028	Short-chain dehydrogenase reductase Sdr
Vch1786_I0563	COG0616	signal peptide processing
Vch1786_I0565	COG1522	sequence-specific DNA binding
Vch1786_I0566	COG1946	Acyl-CoA thioesterase
Vch1786_I0570	COG3706	GGDEF domain
Vch1786_I0572	COG0640	Transcriptional regulator
Vch1786_I0573	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Vch1786_I0579	COG1881	PFAM PEBP family protein
Vch1786_I0583	COG0009	L-threonylcarbamoyladenylate synthase
Vch1786_I0586	COG2201	protein-glutamate methylesterase activity
Vch1786_I0588	COG5002	protein histidine kinase activity
Vch1786_I0589	COG4191	Histidine kinase
Vch1786_I0590	COG5001	Diguanylate cyclase
Vch1786_I0590	COG3300	MHYT domain
Vch1786_I0591	COG2204	response regulator
Vch1786_I0596	COG0601	transmembrane transport
Vch1786_I0597	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vch1786_I0598	COG0444	Belongs to the ABC transporter superfamily
Vch1786_I0599	COG4608	Belongs to the ABC transporter superfamily
Vch1786_I0600	COG0435	Glutathione S-transferase
Vch1786_I0601	COG0280	phosphate acetyltransferase
Vch1786_I0601	COG0857	belongs to the CobB CobQ family
Vch1786_I0602	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Vch1786_I0603	COG3092	negative regulation of chromosome organization
Vch1786_I0604	COG4628	conserved protein (DUF2132)
Vch1786_I0606	COG4120	Belongs to the binding-protein-dependent transport system permease family
Vch1786_I0608	COG2203	Gaf domain
Vch1786_I0608	COG2199	diguanylate cyclase activity
Vch1786_I0609	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Vch1786_I0611	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Vch1786_I0612	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Vch1786_I0614	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Vch1786_I0615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Vch1786_I0616	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Vch1786_I0617	COG0156	8-amino-7-oxononanoate synthase activity
Vch1786_I0618	COG2226	methyltransferase
Vch1786_I0619	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Vch1786_I0621	COG0501	Belongs to the peptidase M48B family
Vch1786_I0623	COG0300	oxidoreductase activity
Vch1786_I0626	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Vch1786_I0628	COG2268	Band 7 protein
Vch1786_I0630	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Vch1786_I0631	COG2915	High frequency lysogenization protein hflD homolog
Vch1786_I0632	COG0482	sulfurtransferase activity
Vch1786_I0633	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vch1786_I0634	COG2916	Histone family protein nucleoid-structuring protein H-NS
Vch1786_I0635	COG1757	Na H antiporter
Vch1786_I0636	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Vch1786_I0637	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Vch1786_I0638	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Vch1786_I0639	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Vch1786_I0639	COG0131	Imidazoleglycerol-phosphate dehydratase
Vch1786_I0640	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Vch1786_I0641	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Vch1786_I0642	COG0107	imidazoleglycerol-phosphate synthase activity
Vch1786_I0643	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Vch1786_I0643	COG0140	phosphoribosyl-ATP diphosphatase activity
Vch1786_I0644	COG1187	pseudouridine synthase activity
Vch1786_I0646	COG1278	Cold shock
Vch1786_I0647	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Vch1786_I0648	COG0542	response to heat
Vch1786_I0650	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Vch1786_I0651	COG1012	belongs to the aldehyde dehydrogenase family
Vch1786_I0651	COG1454	alcohol dehydrogenase
Vch1786_I0652	COG1737	Transcriptional regulator
Vch1786_I0653	COG0076	glutamate decarboxylase activity
Vch1786_I0655	COG2431	L-lysine efflux transmembrane transporter activity
Vch1786_I0657	COG3070	regulator of competence-specific genes
Vch1786_I0660	COG3852	Histidine kinase
Vch1786_I0662	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Vch1786_I0665	COG0189	ligase activity
Vch1786_I0665	COG4067	protein conserved in archaea
Vch1786_I0667	COG0500	methyltransferase
Vch1786_I0668	COG4106	trans-aconitate 2-methyltransferase activity
Vch1786_I0669	COG1801	Protein of unknown function DUF72
Vch1786_I0670	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Vch1786_I0671	COG1435	thymidine kinase activity
Vch1786_I0673	COG0159	tryptophan synthase activity
Vch1786_I0674	COG0133	tryptophan synthase activity
Vch1786_I0675	COG0134	indole-3-glycerol-phosphate synthase activity
Vch1786_I0675	COG0135	phosphoribosylanthranilate isomerase activity
Vch1786_I0676	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Vch1786_I0677	COG0512	Glutamine amidotransferase of anthranilate synthase
Vch1786_I0678	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Vch1786_I0681	COG0613	PHP domain protein
Vch1786_I0682	COG0009	L-threonylcarbamoyladenylate synthase
Vch1786_I0683	COG1187	pseudouridine synthase activity
Vch1786_I0684	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Vch1786_I0685	COG4988	ABC transporter
Vch1786_I0686	COG0492	ferredoxin-NADP+ reductase activity
Vch1786_I0688	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Vch1786_I0689	COG3706	GGDEF domain
Vch1786_I0690	COG2949	membrane
Vch1786_I0692	COG0281	malic enzyme
Vch1786_I0694	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Vch1786_I0699	COG2885	chlorophyll binding
Vch1786_I0702	COG0277	FAD linked oxidase domain protein
Vch1786_I0702	COG0247	lactate metabolic process
Vch1786_I0706	COG2986	histidine ammonia-lyase
Vch1786_I0707	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Vch1786_I0708	COG0010	Belongs to the arginase family
Vch1786_I0709	COG1228	amidohydrolase
Vch1786_I0713	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Vch1786_I0715	COG5001	Diguanylate cyclase
Vch1786_I0716	COG0417	DNA replication proofreading
Vch1786_I0717	COG2197	response regulator
Vch1786_I0718	COG0322	excinuclease ABC activity
Vch1786_I0724	COG3706	GGDEF domain
Vch1786_I0724	COG0745	RESPONSE REGULATOR receiver
Vch1786_I0727	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Vch1786_I0728	COG0072	phenylalanine-tRNA ligase activity
Vch1786_I0728	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Vch1786_I0730	COG0776	regulation of translation
Vch1786_I0733	COG0500	methyltransferase
Vch1786_I0734	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Vch1786_I0736	COG0295	cytidine deaminase activity
Vch1786_I0737	COG1346	cytolysis
Vch1786_I0739	COG2925	Exonuclease
Vch1786_I0741	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vch1786_I0742	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Vch1786_I0743	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Vch1786_I0747	COG2988	succinylglutamate desuccinylase activity
Vch1786_I0748	COG4139	cobalamin transport
Vch1786_I0749	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
Vch1786_I0759	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Vch1786_I0760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Vch1786_I0761	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Vch1786_I0765	COG2814	Major facilitator Superfamily
Vch1786_I0767	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Vch1786_I0772	COG2989	Protein conserved in bacteria
Vch1786_I0773	COG3108	Peptidase M15
Vch1786_I0774	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Vch1786_I0777	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Vch1786_I0782	COG1846	Transcriptional regulator
Vch1786_I0783	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vch1786_I0784	COG0726	polysaccharide deacetylase
Vch1786_I0785	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Vch1786_I0787	COG1447	Phosphotransferase system cellobiose-specific component IIA
Vch1786_I0788	COG1486	melibiose metabolic process
Vch1786_I0789	COG3394	polysaccharide catabolic process
Vch1786_I0790	COG1609	Transcriptional regulator
Vch1786_I0791	COG2943	transferase activity, transferring hexosyl groups
Vch1786_I0792	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
Vch1786_I0793	COG0840	transmembrane signaling receptor activity
Vch1786_I0796	COG1448	Aminotransferase
Vch1786_I0797	COG3437	response regulator, receiver
Vch1786_I0797	COG2770	Histidine kinase
Vch1786_I0798	COG0351	phosphomethylpyrimidine kinase
Vch1786_I0799	COG0017	Asparaginyl-tRNA synthetase
Vch1786_I0801	COG0720	synthase
Vch1786_I0802	COG1760	l-serine dehydratase
Vch1786_I0803	COG0814	amino acid
Vch1786_I0804	COG0494	nUDIX hydrolase
Vch1786_I0805	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Vch1786_I0808	COG3106	COG3106 Predicted ATPase
Vch1786_I0809	COG3768	UPF0283 membrane protein
Vch1786_I0810	COG3283	Transcriptional regulator of aromatic amino acids metabolism
Vch1786_I0811	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vch1786_I0814	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Vch1786_I0816	COG0471	metal ion transport
Vch1786_I0817	COG4191	Histidine kinase
Vch1786_I0817	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vch1786_I0819	COG2990	Protein conserved in bacteria
Vch1786_I0820	COG3713	MltA-interacting MipA family protein
Vch1786_I0821	COG2205	protein histidine kinase activity
Vch1786_I0822	COG0745	RESPONSE REGULATOR receiver
Vch1786_I0828	COG1129	ABC transporter
Vch1786_I0837	COG2186	Transcriptional regulator
Vch1786_I0838	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Vch1786_I0839	COG0372	Belongs to the citrate synthase family
Vch1786_I0845	COG2195	Cleaves the N-terminal amino acid of tripeptides
Vch1786_I0847	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
Vch1786_I0849	COG0625	glutathione transferase activity
Vch1786_I0850	COG3437	response regulator, receiver
Vch1786_I0855	COG3706	GGDEF domain
Vch1786_I0856	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Vch1786_I0857	COG1254	Belongs to the acylphosphatase family
Vch1786_I0858	COG2920	part of a sulfur-relay system
Vch1786_I0859	COG0670	Belongs to the BI1 family
Vch1786_I0860	COG1126	abc transporter atp-binding protein
Vch1786_I0861	COG0765	amino acid transport
Vch1786_I0862	COG4597	amino acid ABC transporter
Vch1786_I0863	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vch1786_I0865	COG0561	phosphatase activity
Vch1786_I0866	COG0602	queuosine metabolic process
Vch1786_I0867	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Vch1786_I0873	COG3706	GGDEF domain
Vch1786_I0874	COG0443	Heat shock 70 kDa protein
Vch1786_I0875	COG0443	Heat shock 70 kDa protein
Vch1786_I0882	COG1643	Atp-dependent helicase
Vch1786_I0886	COG0443	Heat shock 70 kDa protein
Vch1786_I0888	COG0095	Lipoate-protein ligase
Vch1786_I0890	COG0583	DNA-binding transcription factor activity
Vch1786_I0891	COG0477	Major facilitator Superfamily
Vch1786_I0892	COG0415	Belongs to the DNA photolyase family
Vch1786_I0893	COG2076	Multidrug Resistance protein
Vch1786_I0897	COG2198	Histidine kinase
Vch1786_I0897	COG0643	Histidine kinase
Vch1786_I0899	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Vch1786_I0901	COG2201	protein-glutamate methylesterase activity
Vch1786_I0902	COG0835	chemotaxis
Vch1786_I0903	COG0840	transmembrane signaling receptor activity
Vch1786_I0903	COG3290	protein histidine kinase activity
Vch1786_I0904	COG0840	transmembrane signaling receptor activity
Vch1786_I0906	COG0513	Belongs to the DEAD box helicase family
Vch1786_I0908	COG1538	Outer membrane efflux protein
Vch1786_I0909	COG1566	PFAM secretion protein HlyD family protein
Vch1786_I0910	COG2814	Major facilitator Superfamily
Vch1786_I0911	COG0840	transmembrane signaling receptor activity
Vch1786_I0912	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Vch1786_I0915	COG3501	Rhs element vgr protein
Vch1786_I0920	COG1280	lysine exporter protein (LysE YggA)
Vch1786_I0921	COG1115	amino acid carrier protein
Vch1786_I0924	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Vch1786_I0925	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Vch1786_I0926	COG1177	transmembrane transport
Vch1786_I0927	COG1176	ABC-type spermidine putrescine transport system, permease component I
Vch1786_I0928	COG3842	ATPase activity
Vch1786_I0932	COG0037	tRNA processing
Vch1786_I0933	COG0589	response to stress
Vch1786_I0934	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Vch1786_I0937	COG2217	Heavy metal translocating P-type atpase
Vch1786_I0939	COG2010	Cytochrome c
Vch1786_I0942	COG3278	Belongs to the heme-copper respiratory oxidase family
Vch1786_I0945	COG2205	protein histidine kinase activity
Vch1786_I0945	COG0784	Response regulator, receiver
Vch1786_I0950	COG2994	toxin metabolic process
Vch1786_I0951	COG1073	alpha beta
Vch1786_I0951	COG3064	Membrane
Vch1786_I0951	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
Vch1786_I0954	COG4128	Pfam Zonular occludens toxin
Vch1786_I0961	COG1476	TRANSCRIPTIONal
Vch1786_I0966	COG1476	TRANSCRIPTIONal
Vch1786_I0976	COG3328	transposase activity
Vch1786_I0979	COG3120	sequence-specific DNA binding
Vch1786_I0980	COG1067	ATP-dependent peptidase activity
Vch1786_I0981	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Vch1786_I0986	COG0116	Belongs to the methyltransferase superfamily
Vch1786_I0986	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Vch1786_I0990	COG0167	dihydroorotate dehydrogenase activity
Vch1786_I0993	COG0308	aminopeptidase N
Vch1786_I0996	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
Vch1786_I0997	COG1132	(ABC) transporter
Vch1786_I0998	COG1956	GAF domain-containing protein
Vch1786_I0999	COG2995	paraquat-inducible protein a
Vch1786_I1000	COG3008	intermembrane lipid transfer
Vch1786_I1001	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Vch1786_I1001	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Vch1786_I1002	COG2996	Protein conserved in bacteria
Vch1786_I1005	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Vch1786_I1007	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Vch1786_I1010	COG0437	4 iron, 4 sulfur cluster binding
Vch1786_I1011	COG0243	molybdopterin cofactor binding
Vch1786_I1011	COG3383	formate dehydrogenase (NAD+) activity
Vch1786_I1017	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Vch1786_I1018	COG0488	(ABC) transporter
Vch1786_I1019	COG3852	Histidine kinase
Vch1786_I1020	COG2204	response regulator
Vch1786_I1022	COG4662	Binding-protein-dependent transport system inner membrane component
Vch1786_I1023	COG3842	ATPase activity
Vch1786_I1024	COG0746	molybdenum cofactor guanylyltransferase activity
Vch1786_I1030	COG1940	carbohydrate kinase activity
Vch1786_I1033	COG0840	transmembrane signaling receptor activity
Vch1786_I1034	COG0791	NLP P60 protein
Vch1786_I1038	COG0534	Mate efflux family protein
Vch1786_I1040	COG1793	dna ligase
Vch1786_I1042	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
Vch1786_I1043	COG0848	biopolymer transport protein
Vch1786_I1044	COG0811	peptide transport
Vch1786_I1046	COG0811	peptide transport
Vch1786_I1049	COG1175	transmembrane transport
Vch1786_I1050	COG0395	ABC-type sugar transport system, permease component
Vch1786_I1051	COG3842	ATPase activity
Vch1786_I1052	COG1349	DNA-binding transcription factor activity
Vch1786_I1053	COG0584	glycerophosphoryl diester phosphodiesterase
Vch1786_I1054	COG2731	YhcH YjgK YiaL family protein
Vch1786_I1055	COG0251	oxidation-reduction process
Vch1786_I1056	COG1609	Transcriptional regulator
Vch1786_I1057	COG2723	6-phospho-beta-galactosidase activity
Vch1786_I1059	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Vch1786_I1060	COG0583	DNA-binding transcription factor activity
Vch1786_I1064	COG1136	(ABC) transporter
Vch1786_I1064	COG0577	efflux transmembrane transporter activity
Vch1786_I1065	COG1136	(ABC) transporter
Vch1786_I1065	COG0577	efflux transmembrane transporter activity
Vch1786_I1066	COG4591	ABC-type transport system involved in lipoprotein release permease component
Vch1786_I1066	COG1136	(ABC) transporter
Vch1786_I1067	COG1294	oxidase, subunit
Vch1786_I1068	COG1271	oxidase subunit
Vch1786_I1076	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vch1786_I1078	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Vch1786_I1082	COG0753	catalase activity
Vch1786_I1085	COG3527	Alpha-acetolactate decarboxylase
Vch1786_I1086	COG3527	Alpha-acetolactate decarboxylase
Vch1786_I1089	COG2199	diguanylate cyclase activity
Vch1786_I1089	COG2200	EAL domain
Vch1786_I1090	COG3706	GGDEF domain
Vch1786_I1091	COG2017	converts alpha-aldose to the beta-anomer
Vch1786_I1092	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Vch1786_I1093	COG1085	galactose-1-phosphate uridylyltransferase
Vch1786_I1098	COG0745	RESPONSE REGULATOR receiver
Vch1786_I1098	COG3706	GGDEF domain
Vch1786_I1101	COG0835	chemotaxis
Vch1786_I1101	COG0784	Response regulator, receiver
Vch1786_I1103	COG4565	transcriptional regulatory protein
Vch1786_I1104	COG3290	protein histidine kinase activity
Vch1786_I1106	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vch1786_I1110	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Vch1786_I1111	COG3063	Type IV pilus biogenesis stability protein PilW
Vch1786_I1114	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
Vch1786_I1115	COG1451	nucleotide metabolic process
Vch1786_I1117	COG0583	DNA-binding transcription factor activity
Vch1786_I1121	COG1538	Outer membrane efflux protein
Vch1786_I1123	COG0019	diaminopimelate decarboxylase activity
Vch1786_I1124	COG1748	Saccharopine dehydrogenase
Vch1786_I1126	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Vch1786_I1129	COG4181	ATPase activity
Vch1786_I1130	COG0534	Mate efflux family protein
Vch1786_I1131	COG0702	epimerase
Vch1786_I1133	COG2814	Major facilitator Superfamily
Vch1786_I1134	COG1061	Type III restriction enzyme res subunit
Vch1786_I1135	COG1187	pseudouridine synthase activity
Vch1786_I1139	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Vch1786_I1140	COG2203	Gaf domain
Vch1786_I1140	COG5001	Diguanylate cyclase
Vch1786_I1140	COG4251	negative regulation of phosphorylation
Vch1786_I1140	COG3706	GGDEF domain
Vch1786_I1142	COG0840	transmembrane signaling receptor activity
Vch1786_I1148	COG4934	collagen metabolic process
Vch1786_I1153	COG2239	Acts as a magnesium transporter
Vch1786_I1156	COG0814	amino acid
Vch1786_I1157	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vch1786_I1158	COG1131	(ABC) transporter
Vch1786_I1159	COG0842	Transport permease protein
Vch1786_I1161	COG3313	Fe-S protein
Vch1786_I1163	COG4134	Bacterial extracellular solute-binding protein
Vch1786_I1164	COG4135	transport system, permease component
Vch1786_I1165	COG4136	ATPase activity
Vch1786_I1166	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Vch1786_I1168	COG0564	pseudouridine synthase activity
Vch1786_I1169	COG0733	neurotransmitter:sodium symporter activity
Vch1786_I1171	COG0626	cystathionine gamma-synthase activity
Vch1786_I1172	COG2818	Glycosylase
Vch1786_I1175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vch1786_I1178	COG1842	Phage shock protein A
Vch1786_I1179	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Vch1786_I1181	COG4168	peptide transport system, permease
Vch1786_I1182	COG4171	peptide transport system, permease
Vch1786_I1184	COG4172	Belongs to the ABC transporter superfamily
Vch1786_I1187	COG1227	inorganic diphosphatase activity
Vch1786_I1192	COG0243	molybdopterin cofactor binding
Vch1786_I1193	COG3005	denitrification pathway
Vch1786_I1194	COG4459	periplasmic nitrate reductase
Vch1786_I1195	COG2116	formate transmembrane transporter activity
Vch1786_I1197	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Vch1786_I1198	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Vch1786_I1200	COG2917	probably involved in intracellular septation
Vch1786_I1201	COG1607	acyl-coa hydrolase
Vch1786_I1202	COG2350	Protein conserved in bacteria
Vch1786_I1204	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Vch1786_I1205	COG0583	DNA-binding transcription factor activity
Vch1786_I1208	COG0612	Peptidase, M16
Vch1786_I1210	COG1032	radical SAM domain protein
Vch1786_I1213	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Vch1786_I1214	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
Vch1786_I1215	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
Vch1786_I1216	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Vch1786_I1217	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Vch1786_I1218	COG0745	RESPONSE REGULATOR receiver
Vch1786_I1219	COG3381	protein complex oligomerization
Vch1786_I1220	COG1609	Transcriptional regulator
Vch1786_I1221	COG3070	regulator of competence-specific genes
Vch1786_I1225	COG0297	glycogen (starch) synthase activity
Vch1786_I1226	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Vch1786_I1229	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Vch1786_I1231	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Vch1786_I1232	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Vch1786_I1233	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Vch1786_I1234	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Vch1786_I1235	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Vch1786_I1241	COG1012	belongs to the aldehyde dehydrogenase family
Vch1786_I1242	COG1309	transcriptional regulator
Vch1786_I1246	COG0668	transmembrane transport
Vch1786_I1247	COG2995	paraquat-inducible protein a
Vch1786_I1248	COG3008	intermembrane lipid transfer
Vch1786_I1248	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Vch1786_I1250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vch1786_I1253	COG0582	viral genome integration into host DNA
Vch1786_I1254	COG0582	viral genome integration into host DNA
Vch1786_I1255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Vch1786_I1259	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Vch1786_I1263	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Vch1786_I1267	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
Vch1786_I1268	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
Vch1786_I1269	COG1737	Transcriptional regulator
Vch1786_I1270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Vch1786_I1271	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Vch1786_I1272	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Vch1786_I1273	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vch1786_I1274	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
Vch1786_I1275	COG1940	carbohydrate kinase activity
Vch1786_I1276	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Vch1786_I1277	COG4409	exo-alpha-(2->6)-sialidase activity
Vch1786_I1279	COG2003	Belongs to the UPF0758 family
Vch1786_I1284	COG3941	tape measure
Vch1786_I1292	COG0488	(ABC) transporter
Vch1786_I1308	COG0415	Belongs to the DNA photolyase family
Vch1786_I1310	COG4628	conserved protein (DUF2132)
Vch1786_I1311	COG3284	Transcriptional regulator
Vch1786_I1312	COG1012	belongs to the aldehyde dehydrogenase family
Vch1786_I1314	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vch1786_I1315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vch1786_I1316	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vch1786_I1318	COG2207	Transcriptional regulator
Vch1786_I1319	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vch1786_I1319	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vch1786_I1319	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vch1786_I1320	COG1482	cell wall glycoprotein biosynthetic process
Vch1786_I1323	COG0784	Response regulator, receiver
Vch1786_I1323	COG5002	protein histidine kinase activity
Vch1786_I1325	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Vch1786_I1327	COG2885	chlorophyll binding
Vch1786_I1328	COG0823	Involved in the tonB-independent uptake of proteins
Vch1786_I1331	COG0811	peptide transport
Vch1786_I1332	COG0824	Thioesterase
Vch1786_I1333	COG3790	cyd operon protein YbgE
Vch1786_I1334	COG4890	Cyd operon protein YbgT
Vch1786_I1335	COG1294	oxidase, subunit
Vch1786_I1336	COG1271	oxidase subunit
Vch1786_I1337	COG2255	four-way junction helicase activity
Vch1786_I1338	COG0632	four-way junction helicase activity
Vch1786_I1339	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Vch1786_I1340	COG0215	cysteine-tRNA ligase activity
Vch1786_I1341	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Vch1786_I1342	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vch1786_I1343	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Vch1786_I1345	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
Vch1786_I1346	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vch1786_I1347	COG1199	ATP-dependent helicase activity
Vch1786_I1348	COG0730	response to heat
Vch1786_I1349	COG3923	Primosomal replication protein n
Vch1786_I1351	COG0840	transmembrane signaling receptor activity
Vch1786_I1352	COG0708	Exodeoxyribonuclease III
Vch1786_I1353	COG4160	amino acid transport
Vch1786_I1354	COG4215	(ABC) transporter
Vch1786_I1358	COG1882	Formate acetyltransferase
Vch1786_I1360	COG0840	transmembrane signaling receptor activity
Vch1786_I1361	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Vch1786_I1363	COG3013	Belongs to the UPF0304 family
Vch1786_I1364	COG2766	serine protein kinase
Vch1786_I1365	COG2718	Belongs to the UPF0229 family
Vch1786_I1366	COG2719	SpoVR family
Vch1786_I1367	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Vch1786_I1369	COG1663	tetraacyldisaccharide 4'-kinase activity
Vch1786_I1370	COG1132	(ABC) transporter
Vch1786_I1371	COG0658	competence protein
Vch1786_I1371	COG2333	competence protein COMEC
Vch1786_I1373	COG4591	ABC-type transport system involved in lipoprotein release permease component
Vch1786_I1374	COG1136	(ABC) transporter
Vch1786_I1375	COG4591	ABC-type transport system involved in lipoprotein release permease component
Vch1786_I1377	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Vch1786_I1381	COG1252	NADH dehydrogenase
Vch1786_I1388	COG0537	adenosine 5'-monophosphoramidase activity
Vch1786_I1391	COG2186	Transcriptional regulator
Vch1786_I1392	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Vch1786_I1393	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Vch1786_I1394	COG1674	ftsk spoiiie
Vch1786_I1396	COG0686	Belongs to the AlaDH PNT family
Vch1786_I1398	COG0583	DNA-binding transcription factor activity
Vch1786_I1402	COG0284	orotidine-5'-phosphate decarboxylase activity
Vch1786_I1403	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
Vch1786_I1404	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
Vch1786_I1405	COG0776	regulation of translation
Vch1786_I1406	COG0539	negative regulation of cytoplasmic translation
Vch1786_I1407	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Vch1786_I1408	COG1555	photosystem II stabilization
Vch1786_I1409	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vch1786_I1410	COG0776	regulation of translation
Vch1786_I1411	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Vch1786_I1412	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Vch1786_I1414	COG0544	peptidyl-prolyl cis-trans isomerase activity
Vch1786_I1416	COG4191	Histidine kinase
Vch1786_I1418	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Vch1786_I1419	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Vch1786_I1420	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vch1786_I1422	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Vch1786_I1425	COG5001	Diguanylate cyclase
Vch1786_I1425	COG3300	MHYT domain
Vch1786_I1427	COG4589	Belongs to the CDS family
Vch1786_I1435	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Vch1786_I1438	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vch1786_I1442	COG0243	molybdopterin cofactor binding
Vch1786_I1443	COG3005	denitrification pathway
Vch1786_I1444	COG3325	Belongs to the glycosyl hydrolase 18 family
Vch1786_I1444	COG3469	chitinase activity
Vch1786_I1445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Vch1786_I1448	COG2951	lytic endotransglycosylase activity
Vch1786_I1449	COG3100	YcgL domain-containing protein
Vch1786_I1451	COG0850	regulation of cytokinetic process
Vch1786_I1452	COG2894	cell division
Vch1786_I1453	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Vch1786_I1454	COG3015	lipoprotein NlpE involved in copper resistance
Vch1786_I1458	COG0477	Major facilitator Superfamily
Vch1786_I1459	COG0840	transmembrane signaling receptor activity
Vch1786_I1460	COG1396	sequence-specific DNA binding
Vch1786_I1461	COG3135	benzoate transporter
Vch1786_I1464	COG1441	menaquinone biosynthetic process
Vch1786_I1466	COG0596	Alpha beta hydrolase
Vch1786_I1467	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Vch1786_I1468	COG1169	isochorismate synthase
Vch1786_I1469	COG0436	Aminotransferase
Vch1786_I1470	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
Vch1786_I1471	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Vch1786_I1475	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Vch1786_I1476	COG0318	PFAM AMP-dependent synthetase and ligase
Vch1786_I1477	COG0596	Alpha beta hydrolase
Vch1786_I1480	COG1214	PFAM Peptidase M22, glycoprotease
Vch1786_I1481	COG1199	ATP-dependent helicase activity
Vch1786_I1483	COG0788	formyltetrahydrofolate deformylase activity
Vch1786_I1484	COG1902	pentaerythritol trinitrate reductase activity
Vch1786_I1484	COG0446	pyridine nucleotide-disulphide oxidoreductase
Vch1786_I1485	COG0616	signal peptide processing
Vch1786_I1486	COG0252	asparaginase activity
Vch1786_I1487	COG3139	Protein of unknown function (DUF1315)
Vch1786_I1489	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vch1786_I1491	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Vch1786_I1492	COG0676	glucose-6-phosphate 1-epimerase activity
Vch1786_I1494	COG2226	methyltransferase
Vch1786_I1497	COG0835	chemotaxis
Vch1786_I1497	COG0784	Response regulator, receiver
Vch1786_I1498	COG1940	carbohydrate kinase activity
Vch1786_I1500	COG4667	esterase of the alpha-beta hydrolase superfamily
Vch1786_I1503	COG0733	neurotransmitter:sodium symporter activity
Vch1786_I1505	COG1263	PTS System
Vch1786_I1505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vch1786_I1506	COG0084	hydrolase, TatD family'
Vch1786_I1508	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Vch1786_I1509	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Vch1786_I1510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Vch1786_I1511	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Vch1786_I1512	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Vch1786_I1513	COG1028	Short-chain dehydrogenase reductase Sdr
Vch1786_I1514	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Vch1786_I1515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Vch1786_I1516	COG0416	fatty acid biosynthetic process
Vch1786_I1517	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Vch1786_I1518	COG1399	metal-binding, possibly nucleic acid-binding protein
Vch1786_I1519	COG0424	maF-like protein
Vch1786_I1520	COG0564	pseudouridine synthase activity
Vch1786_I1521	COG1530	ribonuclease E activity
Vch1786_I1522	COG0659	secondary active sulfate transmembrane transporter activity
Vch1786_I1524	COG1012	belongs to the aldehyde dehydrogenase family
Vch1786_I1524	COG1454	alcohol dehydrogenase
Vch1786_I1526	COG2095	MarC family integral membrane protein
Vch1786_I1527	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Vch1786_I1528	COG1757	Na H antiporter
Vch1786_I1530	COG3081	Nucleoid-associated protein
Vch1786_I1532	COG3083	sulfuric ester hydrolase activity
Vch1786_I1535	COG0123	including yeast histone deacetylase and acetoin utilization protein
Vch1786_I1536	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Vch1786_I1538	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Vch1786_I1541	COG2853	Lipoprotein
Vch1786_I1543	COG3088	subunit of a heme lyase
Vch1786_I1543	COG4235	cytochrome complex assembly
Vch1786_I1544	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Vch1786_I1545	COG1138	Cytochrome C-type biogenesis protein
Vch1786_I1546	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Vch1786_I1548	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Vch1786_I1549	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Vch1786_I1550	COG4133	protoheme IX ABC transporter activity
Vch1786_I1552	COG0835	chemotaxis
Vch1786_I1554	COG1192	Involved in chromosome partitioning
Vch1786_I1555	COG2201	protein-glutamate methylesterase activity
Vch1786_I1556	COG2198	Histidine kinase
Vch1786_I1556	COG0643	Histidine kinase
Vch1786_I1557	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
Vch1786_I1560	COG0455	bacterial-type flagellum organization
Vch1786_I1564	COG2062	phosphohistidine phosphatase, SixA
Vch1786_I1565	COG1025	Belongs to the peptidase M16 family
Vch1786_I1567	COG0018	arginyl-trna synthetase
Vch1786_I1571	COG1918	ferrous iron import across plasma membrane
Vch1786_I1573	COG4977	sequence-specific DNA binding
Vch1786_I1574	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
Vch1786_I1575	COG1121	(ABC) transporter
Vch1786_I1576	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Vch1786_I1578	COG0045	succinate-CoA ligase (ADP-forming) activity
Vch1786_I1579	COG0508	dehydrogenase complex catalyzes the overall conversion of
Vch1786_I1580	COG0567	Dehydrogenase, E1 component
Vch1786_I1582	COG1053	succinate dehydrogenase
Vch1786_I1583	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Vch1786_I1584	COG2009	succinate dehydrogenase
Vch1786_I1585	COG0372	Belongs to the citrate synthase family
Vch1786_I1586	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Vch1786_I1588	COG0033	Phosphoglucomutase
Vch1786_I1589	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
Vch1786_I1590	COG0596	Alpha beta hydrolase
Vch1786_I1593	COG1346	cytolysis
Vch1786_I1595	COG0583	DNA-binding transcription factor activity
Vch1786_I1597	COG0735	belongs to the Fur family
Vch1786_I1598	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Vch1786_I1599	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vch1786_I1600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Vch1786_I1601	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Vch1786_I1601	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Vch1786_I1602	COG0431	NADPH-dependent FMN reductase
Vch1786_I1604	COG3101	peptidyl-lysine hydroxylation
Vch1786_I1606	COG2860	membrane
Vch1786_I1607	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Vch1786_I1608	COG2890	protein-(glutamine-N5) methyltransferase activity
Vch1786_I1611	COG1684	flagellar biosynthetic protein fliR
Vch1786_I1612	COG1987	bacterial-type flagellum assembly
Vch1786_I1617	COG1580	Controls the rotational direction of flagella during chemotaxis
Vch1786_I1622	COG1317	bacterial-type flagellum organization
Vch1786_I1623	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Vch1786_I1625	COG1677	Flagellar hook-basal body complex protein FliE
Vch1786_I1626	COG2204	response regulator
Vch1786_I1627	COG4191	Histidine kinase
Vch1786_I1628	COG2204	response regulator
Vch1786_I1629	COG1516	flagellar protein fliS
Vch1786_I1631	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Vch1786_I1632	COG1334	flagellar protein FlaG
Vch1786_I1633	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vch1786_I1634	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vch1786_I1635	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vch1786_I1636	COG2837	iron assimilation
Vch1786_I1641	COG1393	Belongs to the ArsC family
Vch1786_I1642	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Vch1786_I1643	COG1876	peptidase activity
Vch1786_I1645	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
Vch1786_I1646	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Vch1786_I1649	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Vch1786_I1653	COG4783	chaperone-mediated protein folding
Vch1786_I1654	COG1393	Belongs to the ArsC family
Vch1786_I1659	COG2233	PERMEase
Vch1786_I1660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Vch1786_I1662	COG0737	Belongs to the 5'-nucleotidase family
Vch1786_I1663	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Vch1786_I1664	COG2912	Transglutaminase-like superfamily
Vch1786_I1665	COG3094	Invasion gene expression up-regulator, SirB
Vch1786_I1666	COG2890	protein-(glutamine-N5) methyltransferase activity
Vch1786_I1667	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Vch1786_I1668	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Vch1786_I1669	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
Vch1786_I1670	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Vch1786_I1671	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Vch1786_I1672	COG0193	aminoacyl-tRNA hydrolase activity
Vch1786_I1673	COG0012	GTP binding
Vch1786_I1680	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vch1786_I1681	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vch1786_I1685	COG3951	Flagellar rod assembly protein muramidase FlgJ
Vch1786_I1685	COG1705	Flagellar rod assembly protein muramidase FlgJ
Vch1786_I1686	COG1706	bacterial-type flagellum-dependent cell motility
Vch1786_I1687	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Vch1786_I1688	COG4786	Flagellar basal body rod
Vch1786_I1689	COG4787	bacterial-type flagellum-dependent cell motility
Vch1786_I1690	COG1749	Flagellar hook protein flgE
Vch1786_I1691	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Vch1786_I1692	COG1558	bacterial-type flagellum-dependent cell motility
Vch1786_I1693	COG1815	bacterial-type flagellum-dependent cell motility
Vch1786_I1694	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Vch1786_I1695	COG0835	chemotaxis
Vch1786_I1695	COG0784	Response regulator, receiver
Vch1786_I1702	COG3433	isochorismatase activity
Vch1786_I1702	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vch1786_I1702	COG2226	methyltransferase
Vch1786_I1703	COG2375	cellular response to nickel ion
Vch1786_I1704	COG4774	siderophore transport
Vch1786_I1704	COG1629	transport
Vch1786_I1707	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Vch1786_I1708	COG2608	mercury ion transmembrane transporter activity
Vch1786_I1708	COG2217	Heavy metal translocating P-type atpase
Vch1786_I1713	COG3735	TraB family
Vch1786_I1716	COG2840	Smr protein MutS2
Vch1786_I1717	COG1187	pseudouridine synthase activity
Vch1786_I1718	COG3706	GGDEF domain
Vch1786_I1719	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Vch1786_I1720	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Vch1786_I1721	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Vch1786_I1723	COG0121	glutamine amidotransferase
Vch1786_I1724	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Vch1786_I1725	COG1960	acyl-CoA dehydrogenase activity
Vch1786_I1727	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Vch1786_I1728	COG0328	RNA-DNA hybrid ribonuclease activity
Vch1786_I1729	COG2226	methyltransferase
Vch1786_I1730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Vch1786_I1731	COG0741	lytic transglycosylase activity
Vch1786_I1731	COG1388	LysM domain
Vch1786_I1733	COG0347	Belongs to the P(II) protein family
Vch1786_I1734	COG3479	Phenolic acid decarboxylase
Vch1786_I1736	COG0037	tRNA processing
Vch1786_I1737	COG0825	malonyl-CoA metabolic process
Vch1786_I1738	COG0587	DNA-directed DNA polymerase activity
Vch1786_I1739	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Vch1786_I1740	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vch1786_I1741	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vch1786_I1742	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Vch1786_I1743	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vch1786_I1744	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
Vch1786_I1746	COG0750	zinc metalloprotease
Vch1786_I1747	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Vch1786_I1748	COG0575	Belongs to the CDS family
Vch1786_I1749	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Vch1786_I1750	COG0233	cytoplasmic translational termination
Vch1786_I1751	COG0528	UMP kinase activity
Vch1786_I1752	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Vch1786_I1753	COG0052	Belongs to the universal ribosomal protein uS2 family
Vch1786_I1754	COG0024	Methionine aminopeptidase
Vch1786_I1755	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Vch1786_I1757	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Vch1786_I1758	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Vch1786_I1759	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Vch1786_I1760	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Vch1786_I1763	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Vch1786_I1763	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Vch1786_I1764	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Vch1786_I1765	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Vch1786_I1766	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Vch1786_I1769	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Vch1786_I1770	COG2252	PERMEase
Vch1786_I1771	COG2195	Cleaves the N-terminal amino acid of tripeptides
Vch1786_I1772	COG0189	ligase activity
Vch1786_I1772	COG4067	protein conserved in archaea
Vch1786_I1773	COG0189	ligase activity
Vch1786_I1775	COG0733	neurotransmitter:sodium symporter activity
Vch1786_I1777	COG3706	GGDEF domain
Vch1786_I1780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Vch1786_I1782	COG1477	protein flavinylation
Vch1786_I1783	COG2871	sodium ion transport
Vch1786_I1784	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Vch1786_I1785	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Vch1786_I1786	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Vch1786_I1787	COG1805	sodium ion transport
Vch1786_I1788	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Vch1786_I1789	COG0271	Belongs to the BolA IbaG family
Vch1786_I1790	COG2813	Specifically methylates the guanine in position
Vch1786_I1792	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Vch1786_I1793	COG2211	Major facilitator Superfamily
Vch1786_I1795	COG1595	DNA-templated transcription, initiation
Vch1786_I1798	COG3248	Nucleoside-binding outer membrane protein
Vch1786_I1800	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Vch1786_I1801	COG0693	protein deglycase activity
Vch1786_I1802	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Vch1786_I1803	COG2166	iron-sulfur cluster assembly
Vch1786_I1804	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Vch1786_I1805	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Vch1786_I1808	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Vch1786_I1808	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Vch1786_I1811	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Vch1786_I1812	COG1074	ATP-dependent DNA helicase activity
Vch1786_I1814	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
Vch1786_I1817	COG3141	response to X-ray
Vch1786_I1819	COG2171	N-acyltransferase activity
Vch1786_I1822	COG0456	acetyltransferase
Vch1786_I1823	COG0569	domain protein
Vch1786_I1823	COG0189	ligase activity
Vch1786_I1826	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Vch1786_I1827	COG1609	Transcriptional regulator
Vch1786_I1828	COG3250	beta-galactosidase activity
Vch1786_I1831	COG1022	Amp-dependent synthetase and ligase
Vch1786_I1832	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Vch1786_I1833	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Vch1786_I1835	COG0560	Phosphoserine phosphatase
Vch1786_I1837	COG0813	purine-nucleoside phosphorylase activity
Vch1786_I1838	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Vch1786_I1839	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Vch1786_I1840	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Vch1786_I1842	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Vch1786_I1843	COG0084	hydrolase, TatD family'
Vch1786_I1845	COG1115	amino acid carrier protein
Vch1786_I1848	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Vch1786_I1849	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Vch1786_I1850	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
Vch1786_I1851	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Vch1786_I1852	COG0083	homoserine kinase activity
Vch1786_I1855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Vch1786_I1857	COG0745	RESPONSE REGULATOR receiver
Vch1786_I1858	COG2198	Histidine kinase
Vch1786_I1858	COG0784	Response regulator, receiver
Vch1786_I1858	COG5002	protein histidine kinase activity
Vch1786_I1859	COG5001	Diguanylate cyclase
Vch1786_I1859	COG3706	GGDEF domain
Vch1786_I1859	COG2203	Gaf domain
Vch1786_I1859	COG4251	negative regulation of phosphorylation
Vch1786_I1860	COG1242	4 iron, 4 sulfur cluster binding
Vch1786_I1862	COG0069	glutamate synthase activity
Vch1786_I1862	COG0070	glutamate synthase
Vch1786_I1862	COG0067	glutamate synthase
Vch1786_I1865	COG0067	glutamate synthase
Vch1786_I1865	COG0070	glutamate synthase
Vch1786_I1865	COG0069	glutamate synthase activity
Vch1786_I1866	COG0493	'glutamate synthase
Vch1786_I1868	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Vch1786_I1870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Vch1786_I1871	COG2860	membrane
Vch1786_I1872	COG0583	DNA-binding transcription factor activity
Vch1786_I1873	COG0730	response to heat
Vch1786_I1875	COG4172	Belongs to the ABC transporter superfamily
Vch1786_I1879	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Vch1786_I1880	COG0505	Belongs to the CarA family
Vch1786_I1882	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Vch1786_I1884	COG0494	nUDIX hydrolase
Vch1786_I1885	COG0653	protein targeting
Vch1786_I1887	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Vch1786_I1888	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Vch1786_I1889	COG0849	cell division
Vch1786_I1890	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Vch1786_I1891	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Vch1786_I1892	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Vch1786_I1893	COG0772	Belongs to the SEDS family
Vch1786_I1894	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Vch1786_I1895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Vch1786_I1896	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Vch1786_I1897	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Vch1786_I1898	COG0768	penicillin binding
Vch1786_I1899	COG3116	cell division
Vch1786_I1900	COG0275	rRNA processing
Vch1786_I1902	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vch1786_I1903	COG0508	dehydrogenase complex catalyzes the overall conversion of
Vch1786_I1904	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Vch1786_I1905	COG2186	Transcriptional regulator
Vch1786_I1906	COG0737	Belongs to the 5'-nucleotidase family
Vch1786_I1907	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Vch1786_I1908	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vch1786_I1909	COG4974	Belongs to the 'phage' integrase family
Vch1786_I1910	COG0716	FMN binding
Vch1786_I1914	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vch1786_I1915	COG1459	type II secretion system
Vch1786_I1917	COG0237	dephospho-CoA kinase activity
Vch1786_I1918	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
Vch1786_I1920	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
Vch1786_I1921	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Vch1786_I1922	COG0187	DNA topoisomerase II activity
Vch1786_I1923	COG3150	esterase
Vch1786_I1925	COG3151	Protein conserved in bacteria
Vch1786_I1926	COG0494	nUDIX hydrolase
Vch1786_I1927	COG1538	Outer membrane efflux protein
Vch1786_I1929	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Vch1786_I1930	COG0840	transmembrane signaling receptor activity
Vch1786_I1931	COG3025	triphosphatase activity
Vch1786_I1932	COG1392	Phosphate transport regulator
Vch1786_I1934	COG0306	phosphate transporter
Vch1786_I1935	COG4991	sh3 domain protein
Vch1786_I1937	COG3409	Peptidoglycan-binding domain 1 protein
Vch1786_I1937	COG3267	Type II secretory pathway component ExeA
Vch1786_I1938	COG0617	tRNA 3'-terminal CCA addition
Vch1786_I1939	COG0148	phosphopyruvate hydratase activity
Vch1786_I1940	COG0504	CTP synthase activity
Vch1786_I1942	COG3956	TIGRFAM MazG family protein
Vch1786_I1943	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Vch1786_I1944	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Vch1786_I1946	COG5001	Diguanylate cyclase
Vch1786_I1949	COG0736	holo-[acyl-carrier-protein] synthase activity
Vch1786_I1950	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Vch1786_I1951	COG1381	Involved in DNA repair and RecF pathway recombination
Vch1786_I1952	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Vch1786_I1953	COG0571	ribonuclease III activity
Vch1786_I1954	COG0681	Belongs to the peptidase S26 family
Vch1786_I1955	COG0481	GTPase activity
Vch1786_I1956	COG3086	response to oxidative stress
Vch1786_I1957	COG3026	antisigma factor binding
Vch1786_I1959	COG1595	DNA-templated transcription, initiation
Vch1786_I1960	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Vch1786_I1961	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
Vch1786_I1962	COG0354	folic acid binding
Vch1786_I1964	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vch1786_I1965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vch1786_I1967	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
Vch1786_I1968	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Vch1786_I1969	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Vch1786_I1970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vch1786_I1971	COG0440	acetolactate synthase activity
Vch1786_I1972	COG0028	Belongs to the TPP enzyme family
Vch1786_I1973	COG1022	Amp-dependent synthetase and ligase
Vch1786_I1974	COG0583	DNA-binding transcription factor activity
Vch1786_I1979	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Vch1786_I1980	COG0473	3-isopropylmalate dehydrogenase activity
Vch1786_I1981	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Vch1786_I1982	COG0066	3-isopropylmalate dehydratase activity
Vch1786_I1992	COG3437	response regulator, receiver
Vch1786_I1995	COG0795	lipopolysaccharide-transporting ATPase activity
Vch1786_I1996	COG0795	lipopolysaccharide-transporting ATPase activity
Vch1786_I1997	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Vch1786_I1998	COG2927	DNA polymerase III (CHI subunit)
Vch1786_I1999	COG0525	valine-tRNA ligase activity
Vch1786_I2000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Vch1786_I2001	COG0564	pseudouridine synthase activity
Vch1786_I2002	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Vch1786_I2004	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Vch1786_I2005	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Vch1786_I2006	COG0540	Belongs to the ATCase OTCase family
Vch1786_I2007	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
Vch1786_I2008	COG0251	oxidation-reduction process
Vch1786_I2009	COG0204	Acyl-transferase
Vch1786_I2010	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Vch1786_I2011	COG5007	Belongs to the BolA IbaG family
Vch1786_I2013	COG2854	intermembrane phospholipid transfer
Vch1786_I2014	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Vch1786_I2015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Vch1786_I2016	COG1127	ABC transporter
Vch1786_I2020	COG0517	IMP dehydrogenase activity
Vch1786_I2020	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Vch1786_I2023	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
Vch1786_I2024	COG1137	ATPase activity
Vch1786_I2026	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Vch1786_I2027	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vch1786_I2028	COG1660	Displays ATPase and GTPase activities
Vch1786_I2029	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vch1786_I2030	COG2239	Acts as a magnesium transporter
Vch1786_I2031	COG0312	modulator of DNA gyrase
Vch1786_I2032	COG3028	Belongs to the UPF0307 family
Vch1786_I2033	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
Vch1786_I2034	COG1178	ABC-type Fe3 transport system permease component
Vch1786_I2035	COG4143	(ABC) transporter
Vch1786_I2036	COG0163	prenyltransferase activity
Vch1786_I2038	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Vch1786_I2039	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Vch1786_I2040	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Vch1786_I2041	COG2105	PFAM AIG2 family protein
Vch1786_I2043	COG0729	surface antigen
Vch1786_I2044	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vch1786_I2045	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
Vch1786_I2048	COG1136	(ABC) transporter
Vch1786_I2053	COG0529	Catalyzes the synthesis of activated sulfate
Vch1786_I2054	COG2895	sulfate adenylyltransferase (ATP) activity
Vch1786_I2055	COG0175	sulfate reduction
Vch1786_I2056	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Vch1786_I2056	COG1648	precorrin-2 dehydrogenase activity
Vch1786_I2057	COG0737	Belongs to the 5'-nucleotidase family
Vch1786_I2059	COG0513	Belongs to the DEAD box helicase family
Vch1786_I2060	COG2153	protein acetylation
Vch1786_I2061	COG0697	spore germination
Vch1786_I2062	COG3266	domain, Protein
Vch1786_I2062	COG3061	Opacity-associated protein A
Vch1786_I2063	COG0545	Peptidyl-prolyl cis-trans isomerase
Vch1786_I2065	COG0203	ribosomal protein L17
Vch1786_I2066	COG0202	RNA polymerase activity
Vch1786_I2067	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Vch1786_I2068	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Vch1786_I2069	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Vch1786_I2071	COG0201	protein transport
Vch1786_I2072	COG0200	Binds to the 23S rRNA
Vch1786_I2073	COG1841	ribosomal large subunit assembly
Vch1786_I2074	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Vch1786_I2075	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Vch1786_I2076	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Vch1786_I2077	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Vch1786_I2078	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Vch1786_I2079	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Vch1786_I2080	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Vch1786_I2081	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Vch1786_I2082	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Vch1786_I2083	COG0255	Belongs to the universal ribosomal protein uL29 family
Vch1786_I2084	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Vch1786_I2085	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Vch1786_I2086	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Vch1786_I2087	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Vch1786_I2088	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Vch1786_I2089	COG0089	rRNA binding
Vch1786_I2090	COG0088	Forms part of the polypeptide exit tunnel
Vch1786_I2091	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Vch1786_I2092	COG0051	transcription antitermination factor activity, RNA binding
Vch1786_I2093	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Vch1786_I2094	COG0557	exoribonuclease II activity
Vch1786_I2095	COG3083	sulfuric ester hydrolase activity
Vch1786_I2096	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
Vch1786_I2097	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Vch1786_I2099	COG1047	Peptidyl-prolyl cis-trans
Vch1786_I2102	COG2249	NAD(P)H dehydrogenase (quinone) activity
Vch1786_I2103	COG0488	(ABC) transporter
Vch1786_I2105	COG0429	hydrolase of the alpha beta-hydrolase fold
Vch1786_I2108	COG3954	Phosphoribulokinase
Vch1786_I2109	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Vch1786_I2111	COG1012	belongs to the aldehyde dehydrogenase family
Vch1786_I2113	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Vch1786_I2115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Vch1786_I2118	COG0180	Tryptophanyl-tRNA synthetase
Vch1786_I2119	COG0546	phosphoglycolate phosphatase activity
Vch1786_I2120	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Vch1786_I2121	COG0338	D12 class N6 adenine-specific DNA methyltransferase
Vch1786_I2123	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Vch1786_I2124	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Vch1786_I2130	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Vch1786_I2132	COG0678	peroxiredoxin activity
Vch1786_I2132	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Vch1786_I2133	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vch1786_I2136	COG0165	Argininosuccinate lyase
Vch1786_I2138	COG0137	argininosuccinate synthase activity
Vch1786_I2139	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Vch1786_I2140	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Vch1786_I2141	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Vch1786_I2142	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Vch1786_I2144	COG1045	serine acetyltransferase
Vch1786_I2145	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Vch1786_I2146	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Vch1786_I2147	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Vch1786_I2148	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
Vch1786_I2149	COG1053	succinate dehydrogenase
Vch1786_I2150	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Vch1786_I2151	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
Vch1786_I2152	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
Vch1786_I2153	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Vch1786_I2154	COG1509	lysine 2,3-aminomutase activity
Vch1786_I2157	COG0459	protein refolding
Vch1786_I2158	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Vch1786_I2163	COG0149	triose-phosphate isomerase activity
Vch1786_I2165	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Vch1786_I2166	COG1575	Belongs to the MenA family. Type 1 subfamily
Vch1786_I2167	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Vch1786_I2168	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Vch1786_I2169	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Vch1786_I2170	COG1609	Transcriptional regulator
Vch1786_I2171	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Vch1786_I2172	COG0254	rRNA binding
Vch1786_I2174	COG0281	malic enzyme
Vch1786_I2175	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
Vch1786_I2176	COG0626	cystathionine gamma-synthase activity
Vch1786_I2177	COG0460	homoserine dehydrogenase
Vch1786_I2177	COG0527	aspartate kinase activity
Vch1786_I2179	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Vch1786_I2180	COG3074	FtsZ-dependent cytokinesis
Vch1786_I2182	COG1494	fructose-1,6-bisphosphatase
Vch1786_I2183	COG0205	6-phosphofructokinase activity
Vch1786_I2184	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Vch1786_I2186	COG0745	RESPONSE REGULATOR receiver
Vch1786_I2187	COG2205	protein histidine kinase activity
Vch1786_I2189	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Vch1786_I2190	COG3030	protein affecting phage T7 exclusion by the F plasmid
Vch1786_I2191	COG3706	GGDEF domain
Vch1786_I2192	COG1027	Aspartate ammonia-lyase
Vch1786_I2193	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Vch1786_I2196	COG4232	protein-disulfide reductase activity
Vch1786_I2198	COG3263	regulation of cellular component size
Vch1786_I2200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Vch1786_I2201	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Vch1786_I2202	COG0194	GDP metabolic process
Vch1786_I2203	COG1758	RNA polymerase activity
Vch1786_I2204	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Vch1786_I2205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Vch1786_I2206	COG2233	PERMEase
Vch1786_I2208	COG0745	RESPONSE REGULATOR receiver
Vch1786_I2209	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Vch1786_I2210	COG2183	response to ionizing radiation
Vch1786_I2212	COG1040	competence protein
Vch1786_I2213	COG0596	Alpha beta hydrolase
Vch1786_I2214	COG0316	Belongs to the HesB IscA family
Vch1786_I2214	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Vch1786_I2215	COG0494	nUDIX hydrolase
Vch1786_I2216	COG1218	3'(2'),5'-bisphosphate nucleotidase
Vch1786_I2218	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
Vch1786_I2219	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
Vch1786_I2220	COG3156	type II secretion system protein K
Vch1786_I2221	COG4795	General secretion pathway protein
Vch1786_I2222	COG2165	general secretion pathway protein
Vch1786_I2223	COG2165	general secretion pathway protein
Vch1786_I2224	COG2165	general secretion pathway protein
Vch1786_I2225	COG1459	type II secretion system
Vch1786_I2226	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vch1786_I2228	COG3031	protein transport across the cell outer membrane
Vch1786_I2229	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Vch1786_I2230	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Vch1786_I2232	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Vch1786_I2234	COG0456	acetyltransferase
Vch1786_I2235	COG1490	D-aminoacyl-tRNA deacylase activity
Vch1786_I2240	COG0174	glutamine synthetase
Vch1786_I2242	COG3852	Histidine kinase
Vch1786_I2244	COG3300	MHYT domain
Vch1786_I2244	COG5001	Diguanylate cyclase
Vch1786_I2245	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Vch1786_I2252	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Vch1786_I2253	COG1404	Belongs to the peptidase S8 family
Vch1786_I2254	COG4206	TonB-dependent receptor
Vch1786_I2255	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Vch1786_I2258	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vch1786_I2259	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Vch1786_I2260	COG2177	Part of the ABC transporter FtsEX involved in
Vch1786_I2261	COG2884	Cell division ATP-binding protein ftsE
Vch1786_I2262	COG0552	protein localization to endoplasmic reticulum
Vch1786_I2263	COG0742	ribosomal rna small subunit methyltransferase
Vch1786_I2270	COG0783	Belongs to the Dps family
Vch1786_I2272	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Vch1786_I2273	COG1280	lysine exporter protein (LysE YggA)
Vch1786_I2274	COG2267	carboxylic ester hydrolase activity
Vch1786_I2275	COG0561	phosphatase activity
Vch1786_I2279	COG3287	FIST C domain
Vch1786_I2279	COG2200	EAL domain
Vch1786_I2279	COG2199	diguanylate cyclase activity
Vch1786_I2280	COG1011	Hydrolase
Vch1786_I2281	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Vch1786_I2283	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Vch1786_I2284	COG0019	diaminopimelate decarboxylase activity
Vch1786_I2285	COG1965	Belongs to the frataxin family
Vch1786_I2287	COG3072	Adenylate cyclase
Vch1786_I2288	COG0181	hydroxymethylbilane synthase activity
Vch1786_I2289	COG1587	Uroporphyrinogen-III synthase
Vch1786_I2290	COG2959	enzyme of heme biosynthesis
Vch1786_I2291	COG3071	HemY protein
Vch1786_I2292	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Vch1786_I2294	COG3078	GTPase activator activity
Vch1786_I2297	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Vch1786_I2299	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Vch1786_I2299	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Vch1786_I2304	COG0084	hydrolase, TatD family'
Vch1786_I2307	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Vch1786_I2309	COG0840	transmembrane signaling receptor activity
Vch1786_I2310	COG1580	Controls the rotational direction of flagella during chemotaxis
Vch1786_I2312	COG3161	chorismate lyase activity
Vch1786_I2313	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Vch1786_I2314	COG2937	Belongs to the GPAT DAPAT family
Vch1786_I2315	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Vch1786_I2317	COG0534	Mate efflux family protein
Vch1786_I2318	COG1858	cytochrome C peroxidase
Vch1786_I2319	COG0805	protein transport
Vch1786_I2320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Vch1786_I2321	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Vch1786_I2322	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Vch1786_I2324	COG2226	methyltransferase
Vch1786_I2325	COG1322	Protein conserved in bacteria
Vch1786_I2327	COG2081	HI0933 family
Vch1786_I2329	COG1528	Iron-storage protein
Vch1786_I2331	COG0589	response to stress
Vch1786_I2332	COG0697	spore germination
Vch1786_I2334	COG0742	ribosomal rna small subunit methyltransferase
Vch1786_I2335	COG5002	protein histidine kinase activity
Vch1786_I2335	COG5001	Diguanylate cyclase
Vch1786_I2336	COG1522	sequence-specific DNA binding
Vch1786_I2340	COG0006	proline dipeptidase activity
Vch1786_I2340	COG0006	proline dipeptidase activity
Vch1786_I2341	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Vch1786_I2342	COG2022	thiamine diphosphate biosynthetic process
Vch1786_I2343	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Vch1786_I2345	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Vch1786_I2346	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Vch1786_I2354	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Vch1786_I2356	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Vch1786_I2357	COG0408	coproporphyrinogen oxidase activity
Vch1786_I2358	COG0009	L-threonylcarbamoyladenylate synthase
Vch1786_I2360	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Vch1786_I2361	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Vch1786_I2362	COG0551	DNA topoisomerase type I activity
Vch1786_I2363	COG2922	Belongs to the Smg family
Vch1786_I2364	COG0758	DNA mediated transformation
Vch1786_I2365	COG1652	LysM domain
Vch1786_I2366	COG0242	peptide deformylase activity
Vch1786_I2367	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Vch1786_I2368	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Vch1786_I2368	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Vch1786_I2369	COG0569	domain protein
Vch1786_I2370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vch1786_I2372	COG1272	protein, Hemolysin III
Vch1786_I2373	COG4326	sporulation control protein
Vch1786_I2375	COG3084	Protein conserved in bacteria
Vch1786_I2377	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Vch1786_I2378	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vch1786_I2379	COG0204	Acyl-transferase
Vch1786_I2380	COG0606	chelatase, subunit chli
Vch1786_I2383	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Vch1786_I2384	COG0129	dihydroxy-acid dehydratase activity
Vch1786_I2386	COG0604	alcohol dehydrogenase
Vch1786_I2388	COG0425	Belongs to the sulfur carrier protein TusA family
Vch1786_I2390	COG2119	membrane
Vch1786_I2391	COG0752	glycyl-tRNA synthetase alpha subunit
Vch1786_I2392	COG0751	glycine-tRNA ligase activity
Vch1786_I2393	COG3977	Valine--pyruvate aminotransferase
Vch1786_I2394	COG0071	Belongs to the small heat shock protein (HSP20) family
Vch1786_I2397	COG0187	DNA topoisomerase II activity
Vch1786_I2398	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Vch1786_I2399	COG0592	DNA-directed DNA polymerase activity
Vch1786_I2400	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Vch1786_I2404	COG1126	abc transporter atp-binding protein
Vch1786_I2405	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Vch1786_I2406	COG0594	ribonuclease P activity
Vch1786_I2407	COG0706	membrane insertase activity
Vch1786_I2408	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Vch1786_I2409	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Vch1786_I2410	COG0445	tRNA wobble uridine modification
Vch1786_I2411	COG0357	Ribosomal RNA small subunit methyltransferase G
Vch1786_I2412	COG1192	Involved in chromosome partitioning
Vch1786_I2413	COG1475	DNA binding
Vch1786_I2414	COG3312	ion transport
Vch1786_I2415	COG0356	it plays a direct role in the translocation of protons across the membrane
Vch1786_I2417	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Vch1786_I2418	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Vch1786_I2419	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Vch1786_I2420	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Vch1786_I2421	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Vch1786_I2422	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Vch1786_I2423	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Vch1786_I2424	COG2814	Major facilitator Superfamily
Vch1786_I2425	COG0583	DNA-binding transcription factor activity
Vch1786_I2426	COG0183	Belongs to the thiolase family
Vch1786_I2427	COG1024	Enoyl-CoA hydratase
Vch1786_I2427	COG1250	3-hydroxyacyl-CoA dehydrogenase
Vch1786_I2428	COG1739	Uncharacterized protein family UPF0029
Vch1786_I2429	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vch1786_I2430	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
Vch1786_I2441	COG0583	DNA-binding transcription factor activity
Vch1786_I2442	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Vch1786_I2443	COG2960	long-chain fatty acid transporting porin activity
Vch1786_I2444	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vch1786_I2445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vch1786_I2446	COG1309	transcriptional regulator
Vch1786_I2455	COG0747	negative chemotaxis
Vch1786_I2457	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vch1786_I2459	COG2131	deaminase
Vch1786_I2469	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vch1786_I2470	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Vch1786_I2473	COG0210	DNA helicase
Vch1786_I2474	COG1280	lysine exporter protein (LysE YggA)
Vch1786_I2477	COG2962	Rard protein
Vch1786_I2478	COG0514	ATP-dependent DNA helicase (RecQ)
Vch1786_I2481	COG1132	(ABC) transporter
Vch1786_I2482	COG4774	siderophore transport
Vch1786_I2483	COG1120	ATPase activity
Vch1786_I2488	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Vch1786_I2489	COG1263	PTS System
Vch1786_I2489	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vch1786_I2491	COG1561	YicC-like family, N-terminal region
Vch1786_I2492	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Vch1786_I2493	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Vch1786_I2494	COG1560	Kdo2-lipid A biosynthetic process
Vch1786_I2495	COG1560	Kdo2-lipid A biosynthetic process
Vch1786_I2497	COG1309	transcriptional regulator
Vch1786_I2498	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Vch1786_I2502	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Vch1786_I2503	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Vch1786_I2505	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Vch1786_I2506	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Vch1786_I2507	COG0859	PFAM glycosyl transferase family 9
Vch1786_I2508	COG0463	Glycosyl transferase, family 2
Vch1786_I2509	COG0859	PFAM glycosyl transferase family 9
Vch1786_I2510	COG3642	lipopolysaccharide core region biosynthetic process
Vch1786_I2517	COG1519	Transferase
Vch1786_I2524	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Vch1786_I2525	COG0662	Cupin 2, conserved barrel domain protein
Vch1786_I2525	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
Vch1786_I2526	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Vch1786_I2527	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Vch1786_I2533	COG0318	PFAM AMP-dependent synthetase and ligase
Vch1786_I2534	COG1454	alcohol dehydrogenase
Vch1786_I2534	COG1012	belongs to the aldehyde dehydrogenase family
Vch1786_I2538	COG5433	transposase activity
Vch1786_I2539	COG5433	transposase activity
Vch1786_I2545	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Vch1786_I2547	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Vch1786_I2548	COG0668	transmembrane transport
Vch1786_I2549	COG1573	uracil-dna glycosylase
Vch1786_I2550	COG3068	Protein conserved in bacteria
Vch1786_I2553	COG1940	carbohydrate kinase activity
Vch1786_I2554	COG1253	flavin adenine dinucleotide binding
Vch1786_I2556	COG0776	regulation of translation
Vch1786_I2558	COG0151	Belongs to the GarS family
Vch1786_I2559	COG0138	bifunctional purine biosynthesis protein purh
Vch1786_I2561	COG0789	Transcriptional regulator
Vch1786_I2562	COG3710	Transcriptional regulator
Vch1786_I2564	COG0531	amino acid
Vch1786_I2565	COG1982	Orn Lys Arg decarboxylase major
Vch1786_I2566	COG0840	transmembrane signaling receptor activity
Vch1786_I2570	COG0800	Aldolase
Vch1786_I2572	COG3265	gluconokinase activity
Vch1786_I2573	COG0129	dihydroxy-acid dehydratase activity
Vch1786_I2574	COG1609	Transcriptional regulator
Vch1786_I2575	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
Vch1786_I2576	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Vch1786_I2578	COG2264	protein methyltransferase activity
Vch1786_I2580	COG0439	Biotin carboxylase
Vch1786_I2581	COG0511	ligase activity, forming carbon-carbon bonds
Vch1786_I2582	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Vch1786_I2583	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Vch1786_I2586	COG2814	Major facilitator Superfamily
Vch1786_I2587	COG2205	protein histidine kinase activity
Vch1786_I2587	COG0784	Response regulator, receiver
Vch1786_I2588	COG0248	Ppx GppA phosphatase
Vch1786_I2589	COG0513	Belongs to the DEAD box helicase family
Vch1786_I2590	COG3118	belongs to the thioredoxin family
Vch1786_I2591	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Vch1786_I2593	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Vch1786_I2605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Vch1786_I2607	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Vch1786_I2609	COG1072	(Pantothenic acid kinase))
Vch1786_I2614	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Vch1786_I2615	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Vch1786_I2616	COG0250	Participates in transcription elongation, termination and antitermination
Vch1786_I2617	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Vch1786_I2618	COG0081	regulation of translation
Vch1786_I2619	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Vch1786_I2620	COG0222	ribosome binding
Vch1786_I2621	COG0085	RNA polymerase activity
Vch1786_I2622	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Vch1786_I2623	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
Vch1786_I2624	COG2816	NAD+ diphosphatase activity
Vch1786_I2625	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Vch1786_I2628	COG4942	peptidase
Vch1786_I2629	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Vch1786_I2631	COG0471	metal ion transport
Vch1786_I2632	COG0688	phosphatidylethanolamine metabolic process
Vch1786_I2633	COG1162	GTPase activity
Vch1786_I2634	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Vch1786_I2644	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Vch1786_I2645	COG0802	atpase or kinase
Vch1786_I2647	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Vch1786_I2648	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Vch1786_I2649	COG1923	regulation of RNA biosynthetic process
Vch1786_I2650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Vch1786_I2651	COG0330	HflC and HflK could
Vch1786_I2652	COG0330	HflC and HflK could
Vch1786_I2653	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
Vch1786_I2654	COG2900	Belongs to the SlyX family
Vch1786_I2657	COG0545	Peptidyl-prolyl cis-trans isomerase
Vch1786_I2658	COG2964	Protein conserved in bacteria
Vch1786_I2659	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
Vch1786_I2660	COG2923	Belongs to the DsrF TusC family
Vch1786_I2662	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Vch1786_I2663	COG0049	tRNA binding
Vch1786_I2664	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Vch1786_I2665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Vch1786_I2667	COG2906	2 iron, 2 sulfur cluster binding
Vch1786_I2669	COG0360	Binds together with S18 to 16S ribosomal RNA
Vch1786_I2670	COG2965	DNA replication, synthesis of RNA primer
Vch1786_I2671	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Vch1786_I2672	COG0359	binds to the 23S rRNA
Vch1786_I2674	COG0305	Participates in initiation and elongation during chromosome replication
Vch1786_I2675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Vch1786_I2676	COG0432	Pfam Uncharacterised protein family UPF0047
Vch1786_I2677	COG0166	Belongs to the GPI family
Vch1786_I2681	COG0735	belongs to the Fur family
Vch1786_I2683	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Vch1786_I2688	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Vch1786_I2689	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Vch1786_I2690	COG0175	sulfate reduction
Vch1786_I2700	COG1410	methionine synthase
Vch1786_I2700	COG0646	methionine synthase
Vch1786_I2701	COG0527	aspartate kinase activity
Vch1786_I2702	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Vch1786_I2704	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Vch1786_I2707	COG0629	single-stranded DNA binding
Vch1786_I2708	COG2199	diguanylate cyclase activity
Vch1786_I2708	COG2200	EAL domain
Vch1786_I2713	COG3267	Type II secretory pathway component ExeA
Vch1786_I2713	COG3409	Peptidoglycan-binding domain 1 protein
Vch1786_I2715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vch1786_I2716	COG1459	type II secretion system
Vch1786_I2724	COG1077	Cell shape determining protein MreB Mrl
Vch1786_I2725	COG1792	Involved in formation and maintenance of cell shape
Vch1786_I2726	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
Vch1786_I2727	COG0424	maF-like protein
Vch1786_I2728	COG1530	ribonuclease E activity
Vch1786_I2729	COG3164	Protein of unknown function
Vch1786_I2730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Vch1786_I2731	COG0312	modulator of DNA gyrase
Vch1786_I2732	COG2235	arginine
Vch1786_I2737	COG0589	response to stress
Vch1786_I2740	COG1438	arginine binding
Vch1786_I2741	COG0039	L-malate dehydrogenase activity
Vch1786_I2742	COG0531	amino acid
Vch1786_I2743	COG0531	amino acid
Vch1786_I2744	COG0142	geranyltranstransferase activity
Vch1786_I2745	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Vch1786_I2746	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Vch1786_I2747	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Vch1786_I2748	COG2966	Psort location CytoplasmicMembrane, score
Vch1786_I2749	COG3610	response to peptide
Vch1786_I2751	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Vch1786_I2752	COG2967	ApaG domain
Vch1786_I2753	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Vch1786_I2754	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Vch1786_I2755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vch1786_I2756	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Vch1786_I2757	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Vch1786_I2769	COG0741	lytic transglycosylase activity
Vch1786_I2770	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
Vch1786_I2771	COG1194	a g-specific adenine glycosylase
Vch1786_I2773	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Vch1786_I2774	COG2066	Belongs to the glutaminase family
Vch1786_I2776	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Vch1786_I2777	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Vch1786_I2779	COG1872	DUF167
Vch1786_I2780	COG0762	integral membrane protein
Vch1786_I2781	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Vch1786_I2782	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Vch1786_I2786	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Vch1786_I2787	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Vch1786_I2788	COG1678	Uncharacterized ACR, COG1678
Vch1786_I2789	COG0189	ligase activity
Vch1786_I2790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Vch1786_I2791	COG2356	endonuclease I
Vch1786_I2792	COG3091	SprT-like family
Vch1786_I2793	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Vch1786_I2795	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Vch1786_I2796	COG0583	DNA-binding transcription factor activity
Vch1786_I2797	COG4771	TonB-dependent receptor
Vch1786_I2798	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Vch1786_I2799	COG0126	phosphoglycerate kinase activity
Vch1786_I2800	COG0191	fructose-bisphosphate aldolase activity
Vch1786_I2802	COG0668	transmembrane transport
Vch1786_I2803	COG1279	arginine transmembrane transporter activity
Vch1786_I2804	COG0583	DNA-binding transcription factor activity
Vch1786_I2807	COG0469	pyruvate kinase activity
Vch1786_I2808	COG1349	DNA-binding transcription factor activity
Vch1786_I2809	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Vch1786_I2810	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Vch1786_I2817	COG2207	Transcriptional regulator
Vch1786_I2819	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Vch1786_I2820	COG0582	viral genome integration into host DNA
Vch1786_I2822	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Vch1786_I2823	COG0358	DNA primase activity
Vch1786_I2824	COG1610	YqeY-like protein
Vch1786_I2825	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Vch1786_I2827	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Vch1786_I2829	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Vch1786_I2830	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Vch1786_I2831	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Vch1786_I2832	COG1968	undecaprenyl-diphosphatase activity
Vch1786_I2833	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Vch1786_I2834	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Vch1786_I2835	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Vch1786_I2836	COG0585	pseudouridine synthase activity
Vch1786_I2837	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Vch1786_I2838	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Vch1786_I2839	COG4942	peptidase
Vch1786_I2839	COG1388	LysM domain
Vch1786_I2840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Vch1786_I2841	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Vch1786_I2846	COG4208	sulfate ABC transporter
Vch1786_I2847	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Vch1786_I2849	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Vch1786_I2850	COG2137	regulation of response to DNA damage stimulus
Vch1786_I2851	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Vch1786_I2852	COG0527	aspartate kinase activity
Vch1786_I2853	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Vch1786_I2862	COG3630	sodium ion export across plasma membrane
Vch1786_I2863	COG0511	ligase activity, forming carbon-carbon bonds
Vch1786_I2863	COG5016	pyruvate
Vch1786_I2864	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
Vch1786_I2866	COG1238	metal cluster binding
Vch1786_I2867	COG0612	Peptidase, M16
Vch1786_I2869	COG2918	glutathione biosynthetic process
Vch1786_I2870	COG1854	S-ribosylhomocysteine lyase activity
Vch1786_I2871	COG4536	flavin adenine dinucleotide binding
Vch1786_I2872	COG4137	Cytochrome C assembly protein
Vch1786_I2873	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Vch1786_I2874	COG0228	four-way junction DNA binding
Vch1786_I2875	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Vch1786_I2876	COG0336	Belongs to the RNA methyltransferase TrmD family
Vch1786_I2877	COG0335	large ribosomal subunit rRNA binding
Vch1786_I2878	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Vch1786_I2879	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Vch1786_I2881	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Vch1786_I2882	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Vch1786_I2883	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Vch1786_I2885	COG0723	plastoquinol--plastocyanin reductase activity
Vch1786_I2886	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Vch1786_I2887	COG2857	Cytochrome c1
Vch1786_I2888	COG0625	glutathione transferase activity
Vch1786_I2889	COG2969	positive regulation of protein catabolic process
Vch1786_I2890	COG2823	Periplasmic or secreted lipoprotein
Vch1786_I2891	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Vch1786_I2892	COG0792	nuclease activity
Vch1786_I2893	COG3107	peptidoglycan biosynthetic process
Vch1786_I2894	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Vch1786_I2897	COG0288	reversible hydration of carbon dioxide
Vch1786_I2898	COG0659	secondary active sulfate transmembrane transporter activity
Vch1786_I2900	COG1131	(ABC) transporter
Vch1786_I2901	COG0842	Transport permease protein
Vch1786_I2902	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Vch1786_II0002	COG0745	RESPONSE REGULATOR receiver
Vch1786_II0003	COG5002	protein histidine kinase activity
Vch1786_II0009	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Vch1786_II0012	COG2814	Major facilitator Superfamily
Vch1786_II0015	COG1686	Belongs to the peptidase S11 family
Vch1786_II0020	COG1943	Transposase
Vch1786_II0021	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Vch1786_II0021	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Vch1786_II0023	COG0509	glycine decarboxylation via glycine cleavage system
Vch1786_II0024	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Vch1786_II0026	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Vch1786_II0028	COG3039	Transposase
Vch1786_II0033	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Vch1786_II0035	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Vch1786_II0036	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Vch1786_II0046	COG1028	Short-chain dehydrogenase reductase Sdr
Vch1786_II0051	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Vch1786_II0058	COG0494	nUDIX hydrolase
Vch1786_II0060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vch1786_II0061	COG3040	lipid binding
Vch1786_II0065	COG3041	Addiction module toxin RelE StbE family
Vch1786_II0080	COG1619	proteins homologs of microcin C7 resistance protein MccF
Vch1786_II0093	COG0346	lactoylglutathione lyase activity
Vch1786_II0096	COG3040	lipid binding
Vch1786_II0098	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Vch1786_II0099	COG1280	lysine exporter protein (LysE YggA)
Vch1786_II0133	COG3549	Plasmid maintenance system killer
Vch1786_II0134	COG3093	addiction module antidote protein HigA
Vch1786_II0135	COG1619	proteins homologs of microcin C7 resistance protein MccF
Vch1786_II0139	COG3040	lipid binding
Vch1786_II0152	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Vch1786_II0153	COG4977	sequence-specific DNA binding
Vch1786_II0162	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
Vch1786_II0163	COG2944	sequence-specific DNA binding
Vch1786_II0165	COG3039	Transposase
Vch1786_II0166	COG0110	maltose O-acetyltransferase activity
Vch1786_II0169	COG0346	lactoylglutathione lyase activity
Vch1786_II0185	COG1943	Transposase
Vch1786_II0195	COG0346	lactoylglutathione lyase activity
Vch1786_II0201	COG1328	CTP reductase activity
Vch1786_II0202	COG0602	queuosine metabolic process
Vch1786_II0204	COG0189	ligase activity
Vch1786_II0204	COG4067	protein conserved in archaea
Vch1786_II0206	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vch1786_II0206	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vch1786_II0206	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
Vch1786_II0207	COG1105	Belongs to the carbohydrate kinase PfkB family
Vch1786_II0208	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vch1786_II0208	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vch1786_II0209	COG1609	Transcriptional regulator
Vch1786_II0210	COG0420	3'-5' exonuclease activity
Vch1786_II0211	COG0419	ATPase involved in DNA repair
Vch1786_II0212	COG2205	protein histidine kinase activity
Vch1786_II0212	COG0784	Response regulator, receiver
Vch1786_II0213	COG0156	8-amino-7-oxononanoate synthase activity
Vch1786_II0215	COG0038	chloride channel
Vch1786_II0216	COG0523	cobalamin synthesis protein
Vch1786_II0218	COG3158	transport of potassium into the cell
Vch1786_II0219	COG0674	pyruvate-flavodoxin oxidoreductase activity
Vch1786_II0219	COG1013	pyruvate-flavodoxin oxidoreductase activity
Vch1786_II0219	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Vch1786_II0219	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Vch1786_II0220	COG2205	protein histidine kinase activity
Vch1786_II0221	COG0745	RESPONSE REGULATOR receiver
Vch1786_II0222	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Vch1786_II0223	COG0586	Pfam SNARE associated Golgi protein
Vch1786_II0225	COG2200	EAL domain
Vch1786_II0227	COG3038	cytochrome b561
Vch1786_II0229	COG2116	formate transmembrane transporter activity
Vch1786_II0231	COG0583	DNA-binding transcription factor activity
Vch1786_II0233	COG3593	DNA synthesis involved in DNA repair
Vch1786_II0234	COG0737	Belongs to the 5'-nucleotidase family
Vch1786_II0237	COG2824	Alkylphosphonate utilization operon protein PhnA
Vch1786_II0248	COG3706	GGDEF domain
Vch1786_II0251	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Vch1786_II0252	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Vch1786_II0254	COG0745	RESPONSE REGULATOR receiver
Vch1786_II0258	COG0023	Translation Initiation Factor
Vch1786_II0260	COG1181	Belongs to the D-alanine--D-alanine ligase family
Vch1786_II0262	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vch1786_II0262	COG1042	CoA-binding domain protein
Vch1786_II0262	COG0045	succinate-CoA ligase (ADP-forming) activity
Vch1786_II0263	COG0583	DNA-binding transcription factor activity
Vch1786_II0264	COG1629	transport
Vch1786_II0264	COG4771	TonB-dependent receptor
Vch1786_II0267	COG2050	protein possibly involved in aromatic compounds catabolism
Vch1786_II0271	COG0625	glutathione transferase activity
Vch1786_II0274	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Vch1786_II0275	COG4172	Belongs to the ABC transporter superfamily
Vch1786_II0276	COG4239	(ABC) transporter, permease
Vch1786_II0277	COG4174	ABC transporter (Permease)
Vch1786_II0278	COG4166	transmembrane transport
Vch1786_II0287	COG3842	ATPase activity
Vch1786_II0289	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Vch1786_II0291	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Vch1786_II0292	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Vch1786_II0293	COG1011	Hydrolase
Vch1786_II0295	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
Vch1786_II0297	COG1970	mechanosensitive ion channel activity
Vch1786_II0299	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Vch1786_II0300	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vch1786_II0300	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vch1786_II0301	COG0302	gtp cyclohydrolase
Vch1786_II0303	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Vch1786_II0305	COG2897	thiosulfate sulfurtransferase activity
Vch1786_II0306	COG2390	Transcriptional regulator
Vch1786_II0307	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Vch1786_II0308	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Vch1786_II0313	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vch1786_II0319	COG0583	DNA-binding transcription factor activity
Vch1786_II0320	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
Vch1786_II0326	COG0640	Transcriptional regulator
Vch1786_II0328	COG0446	pyridine nucleotide-disulphide oxidoreductase
Vch1786_II0337	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vch1786_II0337	COG1263	PTS System
Vch1786_II0339	COG1621	beta-fructofuranosidase activity
Vch1786_II0340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vch1786_II0341	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Vch1786_II0343	COG2885	chlorophyll binding
Vch1786_II0345	COG0545	Peptidyl-prolyl cis-trans isomerase
Vch1786_II0346	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Vch1786_II0347	COG0840	transmembrane signaling receptor activity
Vch1786_II0348	COG3069	C4-dicarboxylate transmembrane transporter activity
Vch1786_II0349	COG1760	l-serine dehydratase
Vch1786_II0355	COG1609	Transcriptional regulator
Vch1786_II0356	COG2197	response regulator
Vch1786_II0357	COG3850	Histidine kinase
Vch1786_II0358	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Vch1786_II0360	COG0243	molybdopterin cofactor binding
Vch1786_II0365	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Vch1786_II0366	COG2197	response regulator
Vch1786_II0367	COG3851	Histidine kinase
Vch1786_II0368	COG2271	Major facilitator Superfamily
Vch1786_II0369	COG1840	ABC-type Fe3 transport system, periplasmic component
Vch1786_II0371	COG3842	ATPase activity
Vch1786_II0372	COG3243	poly(R)-hydroxyalkanoic acid synthase
Vch1786_II0374	COG0183	Belongs to the thiolase family
Vch1786_II0376	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vch1786_II0377	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vch1786_II0381	COG3706	GGDEF domain
Vch1786_II0383	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Vch1786_II0386	COG1979	alcohol dehydrogenase
Vch1786_II0389	COG4191	Histidine kinase
Vch1786_II0390	COG1840	ABC-type Fe3 transport system, periplasmic component
Vch1786_II0392	COG2271	Major facilitator Superfamily
Vch1786_II0393	COG0469	pyruvate kinase activity
Vch1786_II0394	COG2205	protein histidine kinase activity
Vch1786_II0394	COG2198	Histidine kinase
Vch1786_II0394	COG0784	Response regulator, receiver
Vch1786_II0395	COG1879	ABC-type sugar transport system periplasmic component
Vch1786_II0396	COG1803	Methylglyoxal synthase
Vch1786_II0397	COG1335	isochorismatase
Vch1786_II0399	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Vch1786_II0402	COG0210	DNA helicase
Vch1786_II0403	COG1289	transmembrane transporter activity
Vch1786_II0409	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Vch1786_II0410	COG4149	molybdate abc transporter
Vch1786_II0411	COG0725	ABC transporter, periplasmic molybdate-binding protein
Vch1786_II0412	COG1492	cobalamin metabolic process
Vch1786_II0421	COG0784	Response regulator, receiver
Vch1786_II0421	COG5002	protein histidine kinase activity
Vch1786_II0422	COG1879	ABC-type sugar transport system periplasmic component
Vch1786_II0430	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Vch1786_II0431	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Vch1786_II0434	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Vch1786_II0435	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
Vch1786_II0436	COG0247	lactate metabolic process
Vch1786_II0437	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Vch1786_II0438	COG3118	belongs to the thioredoxin family
Vch1786_II0443	COG0583	DNA-binding transcription factor activity
Vch1786_II0445	COG4160	amino acid transport
Vch1786_II0446	COG4215	(ABC) transporter
Vch1786_II0447	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vch1786_II0448	COG1126	abc transporter atp-binding protein
Vch1786_II0451	COG2425	protein containing a von Willebrand factor type A (vWA) domain
Vch1786_II0453	COG0494	nUDIX hydrolase
Vch1786_II0454	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
Vch1786_II0456	COG1309	transcriptional regulator
Vch1786_II0457	COG0513	Belongs to the DEAD box helicase family
Vch1786_II0458	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
Vch1786_II0461	COG0814	amino acid
Vch1786_II0462	COG0840	transmembrane signaling receptor activity
Vch1786_II0463	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Vch1786_II0466	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Vch1786_II0468	COG1984	allophanate hydrolase subunit 2
Vch1786_II0472	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
Vch1786_II0473	COG4181	ATPase activity
Vch1786_II0475	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Vch1786_II0476	COG1716	ATPase activity
Vch1786_II0476	COG5001	Diguanylate cyclase
Vch1786_II0479	COG0484	heat shock protein binding
Vch1786_II0488	COG0546	phosphoglycolate phosphatase activity
Vch1786_II0491	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vch1786_II0492	COG1368	sulfuric ester hydrolase activity
Vch1786_II0494	COG0513	Belongs to the DEAD box helicase family
Vch1786_II0495	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
Vch1786_II0497	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Vch1786_II0499	COG3046	protein related to deoxyribodipyrimidine photolyase
Vch1786_II0501	COG3397	chitin binding
Vch1786_II0502	COG3227	Zinc metalloprotease (Elastase)
Vch1786_II0504	COG0010	Belongs to the arginase family
Vch1786_II0505	COG1166	arginine decarboxylase activity
Vch1786_II0508	COG2239	Acts as a magnesium transporter
Vch1786_II0509	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Vch1786_II0510	COG0459	protein refolding
Vch1786_II0512	COG0527	aspartate kinase activity
Vch1786_II0513	COG0662	Cupin 2, conserved barrel domain protein
Vch1786_II0514	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Vch1786_II0515	COG0456	acetyltransferase
Vch1786_II0517	COG2154	pterin-4-alpha-carbinolamine dehydratase
Vch1786_II0518	COG3186	Phenylalanine-4-hydroxylase
Vch1786_II0519	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Vch1786_II0522	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Vch1786_II0523	COG0583	DNA-binding transcription factor activity
Vch1786_II0526	COG2171	N-acyltransferase activity
Vch1786_II0527	COG1253	flavin adenine dinucleotide binding
Vch1786_II0528	COG1765	OsmC-like protein
Vch1786_II0536	COG0531	amino acid
Vch1786_II0537	COG3706	GGDEF domain
Vch1786_II0539	COG3279	Response regulator of the LytR AlgR family
Vch1786_II0540	COG3275	phosphorelay sensor kinase activity
Vch1786_II0543	COG1136	(ABC) transporter
Vch1786_II0543	COG0577	efflux transmembrane transporter activity
Vch1786_II0544	COG1136	(ABC) transporter
Vch1786_II0548	COG4989	oxidoreductase activity
Vch1786_II0549	COG0366	Alpha amylase catalytic
Vch1786_II0550	COG2067	long-chain fatty acid transport protein
Vch1786_II0551	COG2267	carboxylic ester hydrolase activity
Vch1786_II0554	COG3227	Zinc metalloprotease (Elastase)
Vch1786_II0555	COG3047	cAMP biosynthetic process
Vch1786_II0558	COG1686	Belongs to the peptidase S11 family
Vch1786_II0559	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vch1786_II0560	COG1271	oxidase subunit
Vch1786_II0561	COG1294	oxidase, subunit
Vch1786_II0563	COG3048	D-serine ammonia-lyase activity
Vch1786_II0564	COG0583	DNA-binding transcription factor activity
Vch1786_II0571	COG1063	alcohol dehydrogenase
Vch1786_II0573	COG0693	protein deglycase activity
Vch1786_II0576	COG0346	lactoylglutathione lyase activity
Vch1786_II0580	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Vch1786_II0581	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Vch1786_II0582	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Vch1786_II0583	COG0363	glucosamine-6-phosphate deaminase activity
Vch1786_II0584	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Vch1786_II0589	COG1929	Belongs to the glycerate kinase type-1 family
Vch1786_II0590	COG2610	gluconate transmembrane transporter activity
Vch1786_II0591	COG3835	regulator
Vch1786_II0593	COG0748	coenzyme F420 binding
Vch1786_II0594	COG3721	Heme iron utilization protein
Vch1786_II0596	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
Vch1786_II0597	COG0811	peptide transport
Vch1786_II0598	COG0848	biopolymer transport protein
Vch1786_II0599	COG4558	Periplasmic binding protein
Vch1786_II0600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vch1786_II0601	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Vch1786_II0609	COG3217	Mosc domain protein beta barrel domain protein
Vch1786_II0609	COG0633	Ferredoxin
Vch1786_II0609	COG3217	Mosc domain protein beta barrel domain protein
Vch1786_II0609	COG0633	Ferredoxin
Vch1786_II0610	COG0418	dihydroorotase activity
Vch1786_II0612	COG3152	Membrane
Vch1786_II0614	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Vch1786_II0615	COG2354	Protein conserved in bacteria
Vch1786_II0617	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Vch1786_II0618	COG1278	Cold shock
Vch1786_II0624	COG3706	GGDEF domain
Vch1786_II0625	COG1349	DNA-binding transcription factor activity
Vch1786_II0628	COG3833	ABC-type maltose transport systems, permease component
Vch1786_II0629	COG1175	transmembrane transport
Vch1786_II0633	COG3842	ATPase activity
Vch1786_II0634	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vch1786_II0637	COG0393	Putative heavy-metal-binding
Vch1786_II0639	COG2197	response regulator
Vch1786_II0641	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vch1786_II0642	COG0835	chemotaxis
Vch1786_II0642	COG0784	Response regulator, receiver
Vch1786_II0643	COG1846	Transcriptional regulator
Vch1786_II0644	COG3706	GGDEF domain
Vch1786_II0652	COG0583	DNA-binding transcription factor activity
Vch1786_II0653	COG5001	Diguanylate cyclase
Vch1786_II0655	COG1741	Belongs to the pirin family
Vch1786_II0656	COG3123	guanosine phosphorylase activity
Vch1786_II0658	COG2211	Major facilitator Superfamily
Vch1786_II0661	COG0840	transmembrane signaling receptor activity
Vch1786_II0662	COG1067	ATP-dependent peptidase activity
Vch1786_II0664	COG4172	Belongs to the ABC transporter superfamily
Vch1786_II0669	COG0583	DNA-binding transcription factor activity
Vch1786_II0670	COG1620	l-lactate permease
Vch1786_II0671	COG1304	FMN binding
Vch1786_II0674	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Vch1786_II0676	COG0840	transmembrane signaling receptor activity
Vch1786_II0679	COG0513	Belongs to the DEAD box helicase family
Vch1786_II0680	COG0583	DNA-binding transcription factor activity
Vch1786_II0682	COG1902	pentaerythritol trinitrate reductase activity
Vch1786_II0684	COG1132	(ABC) transporter
Vch1786_II0686	COG1902	pentaerythritol trinitrate reductase activity
Vch1786_II0688	COG1280	lysine exporter protein (LysE YggA)
Vch1786_II0689	COG2207	Transcriptional regulator
Vch1786_II0693	COG1846	Transcriptional regulator
Vch1786_II0694	COG1764	response to oxidative stress
Vch1786_II0696	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vch1786_II0698	COG0697	spore germination
Vch1786_II0700	COG0700	Nucleoside recognition
Vch1786_II0701	COG3366	ferrous iron transmembrane transporter activity
Vch1786_II0703	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Vch1786_II0705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Vch1786_II0706	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Vch1786_II0707	COG2259	Doxx family
Vch1786_II0712	COG0363	glucosamine-6-phosphate deaminase activity
Vch1786_II0715	COG4580	involved in the transport of maltose and maltodextrins
Vch1786_II0718	COG0840	transmembrane signaling receptor activity
Vch1786_II0721	COG0840	transmembrane signaling receptor activity
Vch1786_II0723	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Vch1786_II0724	COG1126	abc transporter atp-binding protein
Vch1786_II0726	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vch1786_II0727	COG4597	amino acid ABC transporter
Vch1786_II0728	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Vch1786_II0729	COG0739	heme binding
Vch1786_II0730	COG2213	PTS system mannitol-specific
Vch1786_II0730	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vch1786_II0731	COG0246	Mannitol dehydrogenase
Vch1786_II0732	COG3722	fumarate hydratase activity
Vch1786_II0733	COG0673	inositol 2-dehydrogenase activity
Vch1786_II0739	COG2910	NAD(P)H-binding
Vch1786_II0741	COG0840	transmembrane signaling receptor activity
Vch1786_II0742	COG4221	oxidoreductase activity
Vch1786_II0744	COG1901	pseudouridine methyltransferase
Vch1786_II0746	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Vch1786_II0748	COG0531	amino acid
Vch1786_II0749	COG1982	Orn Lys Arg decarboxylase major
Vch1786_II0757	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Vch1786_II0762	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Vch1786_II0764	COG0259	pyridoxamine-phosphate oxidase activity
Vch1786_II0770	COG0745	RESPONSE REGULATOR receiver
Vch1786_II0774	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Vch1786_II0775	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Vch1786_II0776	COG0840	transmembrane signaling receptor activity
Vch1786_II0777	COG0835	chemotaxis
Vch1786_II0778	COG0835	chemotaxis
Vch1786_II0779	COG0643	Histidine kinase
Vch1786_II0779	COG2198	Histidine kinase
Vch1786_II0783	COG0601	transmembrane transport
Vch1786_II0784	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vch1786_II0786	COG2194	sulfuric ester hydrolase activity
Vch1786_II0788	COG0642	Histidine kinase
Vch1786_II0789	COG0745	RESPONSE REGULATOR receiver
Vch1786_II0794	COG1444	tRNA N-acetyltransferase activity
Vch1786_II0795	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Vch1786_II0803	COG0217	transcriptional regulatory protein
Vch1786_II0804	COG2084	Dehydrogenase
Vch1786_II0808	COG2909	trisaccharide binding
Vch1786_II0810	COG0058	SHG alpha-glucan phosphorylase activity
Vch1786_II0811	COG1640	4-alpha-glucanotransferase
Vch1786_II0812	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Vch1786_II0814	COG3501	Rhs element vgr protein
Vch1786_II0821	COG0471	metal ion transport
Vch1786_II0822	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
Vch1786_II0831	COG0671	phosphoesterase, PA-phosphatase related
Vch1786_II0832	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
Vch1786_II0834	COG1999	signal sequence binding
Vch1786_II0838	COG0786	glutamate:sodium symporter activity
Vch1786_II0843	COG1566	PFAM secretion protein HlyD family protein
Vch1786_II0845	COG3706	GGDEF domain
Vch1786_II0848	COG0813	purine-nucleoside phosphorylase activity
Vch1786_II0850	COG3272	Protein of unknown function (DUF1722)
Vch1786_II0852	COG0415	Belongs to the DNA photolyase family
Vch1786_II0853	COG1388	LysM domain
Vch1786_II0853	COG1376	ErfK ybiS ycfS ynhG family protein
Vch1786_II0856	COG0513	Belongs to the DEAD box helicase family
Vch1786_II0858	COG1770	oligopeptidase
Vch1786_II0864	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Vch1786_II0865	COG0573	inorganic phosphate transmembrane transporter activity
Vch1786_II0866	COG0581	inorganic phosphate transmembrane transporter activity
Vch1786_II0867	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Vch1786_II0871	COG0659	secondary active sulfate transmembrane transporter activity
Vch1786_II0873	COG0739	heme binding
Vch1786_II0874	COG3300	MHYT domain
Vch1786_II0874	COG5001	Diguanylate cyclase
Vch1786_II0876	COG2814	Major facilitator Superfamily
Vch1786_II0877	COG0583	DNA-binding transcription factor activity
Vch1786_II0882	COG1301	dicarboxylic acid transport
Vch1786_II0885	COG1342	Belongs to the UPF0251 family
Vch1786_II0893	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Vch1786_II0894	COG0673	inositol 2-dehydrogenase activity
Vch1786_II0896	COG2771	luxR family
Vch1786_II0896	COG2200	EAL domain
Vch1786_II0897	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Vch1786_II0899	COG0564	pseudouridine synthase activity
Vch1786_II0916	COG3501	Rhs element vgr protein
Vch1786_II0920	COG1869	D-ribose catabolic process
Vch1786_II0921	COG1129	ABC transporter
Vch1786_II0922	COG1172	Belongs to the binding-protein-dependent transport system permease family
Vch1786_II0923	COG1879	ABC-type sugar transport system periplasmic component
Vch1786_II0924	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vch1786_II0925	COG1609	Transcriptional regulator
Vch1786_II0927	COG3201	nicotinamide mononucleotide transporter
Vch1786_II0928	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
Vch1786_II0930	COG0584	glycerophosphoryl diester phosphodiesterase
Vch1786_II0931	COG2271	Major facilitator Superfamily
Vch1786_II0940	COG0579	oxidoreductase
Vch1786_II0943	COG0242	peptide deformylase activity
Vch1786_II0945	COG1320	monovalent cation:proton antiporter activity
Vch1786_II0946	COG2212	antiporter activity
Vch1786_II0950	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Vch1786_II0950	COG2111	Na H antiporter
Vch1786_II0952	COG0589	response to stress
Vch1786_II0953	COG0814	amino acid
Vch1786_II0954	COG3033	Beta-eliminating lyase
Vch1786_II0957	COG3530	Putative quorum-sensing-regulated virulence factor
Vch1786_II0959	COG5001	Diguanylate cyclase
Vch1786_II0959	COG5002	protein histidine kinase activity
Vch1786_II0960	COG1278	Cold shock
Vch1786_II0964	COG2304	oxidoreductase activity
Vch1786_II0968	COG0714	Associated with various cellular activities
Vch1786_II0969	COG0840	transmembrane signaling receptor activity
Vch1786_II0973	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Vch1786_II0974	COG2195	Cleaves the N-terminal amino acid of tripeptides
Vch1786_II0977	COG3604	Transcriptional regulator
Vch1786_II0978	COG1017	nitric oxide dioxygenase activity
Vch1786_II0978	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Vch1786_II0979	COG1278	Cold shock
Vch1786_II0985	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Vch1786_II0985	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Vch1786_II0986	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Vch1786_II0988	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Vch1786_II0991	COG0516	GMP reductase activity
Vch1786_II0996	COG1943	Transposase
Vch1786_II0997	COG0513	Belongs to the DEAD box helicase family
Vch1786_II0998	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Vch1786_II1000	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Vch1786_II1001	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Vch1786_II1002	COG0784	Response regulator, receiver
Vch1786_II1002	COG3437	response regulator, receiver
Vch1786_II1003	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vch1786_II1003	COG4191	Histidine kinase
Vch1786_II1005	COG1757	Na H antiporter
Vch1786_II1006	COG2814	Major facilitator Superfamily
Vch1786_II1008	COG3706	GGDEF domain
Vch1786_II1009	COG3240	lipase activity
Vch1786_II1012	COG0840	transmembrane signaling receptor activity
Vch1786_II1013	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
Vch1786_II1014	COG5380	lipid catabolic process
Vch1786_II1015	COG4412	M6 family metalloprotease domain protein
Vch1786_II1015	COG3291	Pkd domain containing protein
Vch1786_II1020	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vch1786_II1021	COG4605	iron ion homeostasis
Vch1786_II1022	COG4604	ABC transporter, ATP-binding protein
Vch1786_II1026	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Vch1786_II1030	COG0745	RESPONSE REGULATOR receiver
Vch1786_II1032	COG3623	hexulose-6-phosphate isomerase
Vch1786_II1033	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
Vch1786_II1034	COG0561	phosphatase activity
Vch1786_II1040	COG3038	cytochrome b561
Vch1786_II1041	COG0366	Alpha amylase catalytic