locus-tag	class	description
N900_00005	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N900_00010	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
N900_00015	COG0706	membrane insertase activity
N900_00020	COG0594	ribonuclease P activity
N900_00025	COG0230	Belongs to the bacterial ribosomal protein bL34 family
N900_00030	COG1126	abc transporter atp-binding protein
N900_00045	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
N900_00050	COG0592	DNA-directed DNA polymerase activity
N900_00055	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N900_00060	COG0187	DNA topoisomerase II activity
N900_00075	COG0071	Belongs to the small heat shock protein (HSP20) family
N900_00080	COG3977	Valine--pyruvate aminotransferase
N900_00085	COG0751	glycine-tRNA ligase activity
N900_00090	COG0752	glycyl-tRNA synthetase alpha subunit
N900_00095	COG2119	membrane
N900_00105	COG0425	Belongs to the sulfur carrier protein TusA family
N900_00115	COG0604	alcohol dehydrogenase
N900_00125	COG0129	dihydroxy-acid dehydratase activity
N900_00130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N900_00145	COG0606	chelatase, subunit chli
N900_00150	COG0204	Acyl-transferase
N900_00155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N900_00160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N900_00170	COG3084	Protein conserved in bacteria
N900_00180	COG4326	sporulation control protein
N900_00185	COG1272	protein, Hemolysin III
N900_00195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N900_00200	COG0569	domain protein
N900_00205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N900_00205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
N900_00210	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N900_00215	COG0242	peptide deformylase activity
N900_00220	COG1652	LysM domain
N900_00225	COG0758	DNA mediated transformation
N900_00230	COG2922	Belongs to the Smg family
N900_00235	COG0551	DNA topoisomerase type I activity
N900_00240	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N900_00245	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
N900_00250	COG0009	L-threonylcarbamoyladenylate synthase
N900_00255	COG0408	coproporphyrinogen oxidase activity
N900_00260	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
N900_00270	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N900_00310	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N900_00315	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
N900_00325	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N900_00330	COG2104	thiamine diphosphate biosynthetic process
N900_00335	COG2022	thiamine diphosphate biosynthetic process
N900_00340	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
N900_00345	COG0006	proline dipeptidase activity
N900_00345	COG0006	proline dipeptidase activity
N900_00365	COG1522	sequence-specific DNA binding
N900_00370	COG5002	protein histidine kinase activity
N900_00370	COG5001	Diguanylate cyclase
N900_00375	COG0742	ribosomal rna small subunit methyltransferase
N900_00385	COG0697	spore germination
N900_00390	COG0589	response to stress
N900_00395	COG1528	Iron-storage protein
N900_00405	COG2081	HI0933 family
N900_00415	COG1322	Protein conserved in bacteria
N900_00420	COG2226	methyltransferase
N900_00430	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N900_00435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N900_00440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N900_00445	COG0805	protein transport
N900_00450	COG1858	cytochrome C peroxidase
N900_00455	COG0534	Mate efflux family protein
N900_00465	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N900_00470	COG2937	Belongs to the GPAT DAPAT family
N900_00475	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
N900_00480	COG3161	chorismate lyase activity
N900_00485	COG1580	Controls the rotational direction of flagella during chemotaxis
N900_00490	COG0840	transmembrane signaling receptor activity
N900_00505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N900_00510	COG0084	hydrolase, TatD family'
N900_00525	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N900_00525	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N900_00530	COG0218	Necessary for normal cell division and for the maintenance of normal septation
N900_00545	COG3078	GTPase activator activity
N900_00555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N900_00560	COG3071	HemY protein
N900_00565	COG2959	enzyme of heme biosynthesis
N900_00570	COG1587	Uroporphyrinogen-III synthase
N900_00575	COG0181	hydroxymethylbilane synthase activity
N900_00585	COG3072	Adenylate cyclase
N900_00590	COG1965	Belongs to the frataxin family
N900_00600	COG0019	diaminopimelate decarboxylase activity
N900_00605	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
N900_00615	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
N900_00620	COG1011	Hydrolase
N900_00625	COG2200	EAL domain
N900_00625	COG2199	diguanylate cyclase activity
N900_00625	COG3287	FIST C domain
N900_00640	COG0561	phosphatase activity
N900_00645	COG2267	carboxylic ester hydrolase activity
N900_00650	COG1280	lysine exporter protein (LysE YggA)
N900_00655	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
N900_00660	COG0783	Belongs to the Dps family
N900_00695	COG0742	ribosomal rna small subunit methyltransferase
N900_00700	COG0552	protein localization to endoplasmic reticulum
N900_00705	COG2884	Cell division ATP-binding protein ftsE
N900_00710	COG2177	Part of the ABC transporter FtsEX involved in
N900_00715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N900_00720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N900_00735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N900_00740	COG4206	TonB-dependent receptor
N900_00745	COG1404	Belongs to the peptidase S8 family
N900_00750	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N900_00785	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N900_00790	COG5001	Diguanylate cyclase
N900_00790	COG3300	MHYT domain
N900_00800	COG3852	Histidine kinase
N900_00815	COG0174	glutamine synthetase
N900_00840	COG1490	D-aminoacyl-tRNA deacylase activity
N900_00845	COG0456	acetyltransferase
N900_00855	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
N900_00860	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
N900_00865	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
N900_00870	COG3031	protein transport across the cell outer membrane
N900_00880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N900_00885	COG1459	type II secretion system
N900_00890	COG2165	general secretion pathway protein
N900_00895	COG2165	general secretion pathway protein
N900_00900	COG2165	general secretion pathway protein
N900_00905	COG4795	General secretion pathway protein
N900_00910	COG3156	type II secretion system protein K
N900_00915	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
N900_00920	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
N900_00930	COG1218	3'(2'),5'-bisphosphate nucleotidase
N900_00935	COG0494	nUDIX hydrolase
N900_00940	COG0316	Belongs to the HesB IscA family
N900_00940	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
N900_00945	COG1040	competence protein
N900_00950	COG0596	Alpha beta hydrolase
N900_00960	COG2183	response to ionizing radiation
N900_00965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N900_00970	COG0745	RESPONSE REGULATOR receiver
N900_00980	COG2233	PERMEase
N900_00985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N900_00990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N900_00995	COG1758	RNA polymerase activity
N900_01000	COG0194	GDP metabolic process
N900_01005	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
N900_01010	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N900_01020	COG3263	regulation of cellular component size
N900_01030	COG4232	protein-disulfide reductase activity
N900_01040	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
N900_01045	COG1027	Aspartate ammonia-lyase
N900_01050	COG3706	GGDEF domain
N900_01055	COG3030	protein affecting phage T7 exclusion by the F plasmid
N900_01060	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N900_01070	COG2205	protein histidine kinase activity
N900_01075	COG0745	RESPONSE REGULATOR receiver
N900_01085	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N900_01090	COG0205	6-phosphofructokinase activity
N900_01095	COG1494	fructose-1,6-bisphosphatase
N900_01100	COG3074	FtsZ-dependent cytokinesis
N900_01105	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N900_01115	COG0460	homoserine dehydrogenase
N900_01115	COG0527	aspartate kinase activity
N900_01120	COG0626	cystathionine gamma-synthase activity
N900_01125	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
N900_01130	COG0281	malic enzyme
N900_01135	COG0254	rRNA binding
N900_01140	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N900_01145	COG1609	Transcriptional regulator
N900_01150	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
N900_01155	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
N900_01160	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
N900_01165	COG1575	Belongs to the MenA family. Type 1 subfamily
N900_01170	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N900_01180	COG0149	triose-phosphate isomerase activity
N900_01205	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
N900_01210	COG0459	protein refolding
N900_01220	COG1509	lysine 2,3-aminomutase activity
N900_01225	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N900_01230	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
N900_01235	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
N900_01240	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N900_01245	COG1053	succinate dehydrogenase
N900_01250	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
N900_01255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N900_01260	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
N900_01265	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N900_01270	COG1045	serine acetyltransferase
N900_01280	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
N900_01285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N900_01290	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
N900_01295	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
N900_01300	COG0137	argininosuccinate synthase activity
N900_01305	COG0165	Argininosuccinate lyase
N900_01315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N900_01320	COG0678	peroxiredoxin activity
N900_01320	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N900_01330	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
N900_01360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
N900_01365	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
N900_01375	COG0338	D12 class N6 adenine-specific DNA methyltransferase
N900_01380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N900_01385	COG0546	phosphoglycolate phosphatase activity
N900_01390	COG0180	Tryptophanyl-tRNA synthetase
N900_01405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N900_01415	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N900_01425	COG1012	belongs to the aldehyde dehydrogenase family
N900_01435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N900_01440	COG3954	Phosphoribulokinase
N900_01450	COG0429	hydrolase of the alpha beta-hydrolase fold
N900_01460	COG0488	(ABC) transporter
N900_01465	COG2249	NAD(P)H dehydrogenase (quinone) activity
N900_01480	COG1047	Peptidyl-prolyl cis-trans
N900_01490	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
N900_01495	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
N900_01500	COG3083	sulfuric ester hydrolase activity
N900_01505	COG0557	exoribonuclease II activity
N900_01510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N900_01515	COG0051	transcription antitermination factor activity, RNA binding
N900_01520	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
N900_01525	COG0088	Forms part of the polypeptide exit tunnel
N900_01530	COG0089	rRNA binding
N900_01535	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
N900_01540	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
N900_01545	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
N900_01550	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
N900_01555	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
N900_01560	COG0255	Belongs to the universal ribosomal protein uL29 family
N900_01565	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
N900_01570	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
N900_01575	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
N900_01580	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
N900_01585	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
N900_01590	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
N900_01595	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
N900_01600	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
N900_01605	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
N900_01610	COG1841	ribosomal large subunit assembly
N900_01615	COG0200	Binds to the 23S rRNA
N900_01620	COG0201	protein transport
N900_01630	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
N900_01635	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
N900_01640	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
N900_01645	COG0202	RNA polymerase activity
N900_01650	COG0203	ribosomal protein L17
N900_01660	COG0545	Peptidyl-prolyl cis-trans isomerase
N900_01665	COG3266	domain, Protein
N900_01665	COG3061	Opacity-associated protein A
N900_01670	COG0697	spore germination
N900_01675	COG2153	protein acetylation
N900_01680	COG0513	Belongs to the DEAD box helicase family
N900_01690	COG0737	Belongs to the 5'-nucleotidase family
N900_01695	COG1648	precorrin-2 dehydrogenase activity
N900_01695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N900_01700	COG0175	sulfate reduction
N900_01705	COG2895	sulfate adenylyltransferase (ATP) activity
N900_01710	COG0529	Catalyzes the synthesis of activated sulfate
N900_01730	COG1136	(ABC) transporter
N900_01745	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
N900_01750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N900_01755	COG0729	surface antigen
N900_01765	COG2105	PFAM AIG2 family protein
N900_01770	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
N900_01775	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
N900_01780	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N900_01785	COG0163	prenyltransferase activity
N900_01790	COG4143	(ABC) transporter
N900_01795	COG1178	ABC-type Fe3 transport system permease component
N900_01800	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
N900_01805	COG3028	Belongs to the UPF0307 family
N900_01810	COG0312	modulator of DNA gyrase
N900_01815	COG2239	Acts as a magnesium transporter
N900_01820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N900_01825	COG1660	Displays ATPase and GTPase activities
N900_01830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N900_01835	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N900_01845	COG1137	ATPase activity
N900_01850	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
N900_01865	COG0517	IMP dehydrogenase activity
N900_01865	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
N900_01875	COG1127	ABC transporter
N900_01880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
N900_01885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
N900_01890	COG2854	intermembrane phospholipid transfer
N900_01900	COG5007	Belongs to the BolA IbaG family
N900_01905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N900_01910	COG0204	Acyl-transferase
N900_01915	COG0251	oxidation-reduction process
N900_01920	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
N900_01925	COG0540	Belongs to the ATCase OTCase family
N900_01935	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N900_01940	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
N900_01950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N900_01955	COG0564	pseudouridine synthase activity
N900_01960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N900_01965	COG0525	valine-tRNA ligase activity
N900_01970	COG2927	DNA polymerase III (CHI subunit)
N900_01975	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N900_01980	COG0795	lipopolysaccharide-transporting ATPase activity
N900_01985	COG0795	lipopolysaccharide-transporting ATPase activity
N900_02000	COG3437	response regulator, receiver
N900_02045	COG0066	3-isopropylmalate dehydratase activity
N900_02050	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
N900_02055	COG0473	3-isopropylmalate dehydrogenase activity
N900_02060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N900_02080	COG0583	DNA-binding transcription factor activity
N900_02085	COG1022	Amp-dependent synthetase and ligase
N900_02090	COG0028	Belongs to the TPP enzyme family
N900_02095	COG0440	acetolactate synthase activity
N900_02100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N900_02105	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
N900_02110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N900_02115	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
N900_02125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N900_02130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N900_02140	COG0354	folic acid binding
N900_02145	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
N900_02155	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
N900_02160	COG1595	DNA-templated transcription, initiation
N900_02170	COG3026	antisigma factor binding
N900_02175	COG3086	response to oxidative stress
N900_02180	COG0481	GTPase activity
N900_02185	COG0681	Belongs to the peptidase S26 family
N900_02190	COG0571	ribonuclease III activity
N900_02195	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N900_02200	COG1381	Involved in DNA repair and RecF pathway recombination
N900_02205	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
N900_02210	COG0736	holo-[acyl-carrier-protein] synthase activity
N900_02225	COG5001	Diguanylate cyclase
N900_02235	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N900_02240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N900_02245	COG3956	TIGRFAM MazG family protein
N900_02250	COG0504	CTP synthase activity
N900_02255	COG0148	phosphopyruvate hydratase activity
N900_02260	COG0617	tRNA 3'-terminal CCA addition
N900_02265	COG3409	Peptidoglycan-binding domain 1 protein
N900_02265	COG3267	Type II secretory pathway component ExeA
N900_02275	COG4991	sh3 domain protein
N900_02280	COG0306	phosphate transporter
N900_02285	COG1392	Phosphate transport regulator
N900_02290	COG3025	triphosphatase activity
N900_02300	COG0840	transmembrane signaling receptor activity
N900_02305	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
N900_02315	COG1538	Outer membrane efflux protein
N900_02320	COG0494	nUDIX hydrolase
N900_02325	COG3151	Protein conserved in bacteria
N900_02335	COG3150	esterase
N900_02340	COG0187	DNA topoisomerase II activity
N900_02345	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N900_02350	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
N900_02360	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
N900_02365	COG0237	dephospho-CoA kinase activity
N900_02375	COG1459	type II secretion system
N900_02380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N900_02400	COG0716	FMN binding
N900_02405	COG4974	Belongs to the 'phage' integrase family
N900_02410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N900_02415	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N900_02420	COG0737	Belongs to the 5'-nucleotidase family
N900_02425	COG2186	Transcriptional regulator
N900_02430	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
N900_02435	COG0508	dehydrogenase complex catalyzes the overall conversion of
N900_02440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N900_02450	COG0275	rRNA processing
N900_02455	COG3116	cell division
N900_02460	COG0768	penicillin binding
N900_02465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N900_02470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N900_02475	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N900_02480	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N900_02485	COG0772	Belongs to the SEDS family
N900_02490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N900_02495	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N900_02500	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N900_02505	COG0849	cell division
N900_02510	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N900_02515	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
N900_02525	COG0653	protein targeting
N900_02530	COG0494	nUDIX hydrolase
N900_02535	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N900_02545	COG0505	Belongs to the CarA family
N900_02550	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N900_02570	COG4172	Belongs to the ABC transporter superfamily
N900_02580	COG0730	response to heat
N900_02585	COG0583	DNA-binding transcription factor activity
N900_02590	COG2860	membrane
N900_02595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N900_02605	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N900_02615	COG0493	'glutamate synthase
N900_02620	COG0067	glutamate synthase
N900_02620	COG0070	glutamate synthase
N900_02620	COG0069	glutamate synthase activity
N900_02630	COG0067	glutamate synthase
N900_02630	COG0070	glutamate synthase
N900_02630	COG0069	glutamate synthase activity
N900_02635	COG1242	4 iron, 4 sulfur cluster binding
N900_02640	COG3706	GGDEF domain
N900_02640	COG4251	negative regulation of phosphorylation
N900_02640	COG2203	Gaf domain
N900_02640	COG5001	Diguanylate cyclase
N900_02645	COG0784	Response regulator, receiver
N900_02645	COG2198	Histidine kinase
N900_02645	COG5002	protein histidine kinase activity
N900_02650	COG0745	RESPONSE REGULATOR receiver
N900_02660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N900_02675	COG0083	homoserine kinase activity
N900_02680	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N900_02685	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
N900_02690	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
N900_02695	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
N900_02710	COG1115	amino acid carrier protein
N900_02720	COG0084	hydrolase, TatD family'
N900_02725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N900_02730	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N900_02735	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
N900_02740	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
N900_02745	COG0813	purine-nucleoside phosphorylase activity
N900_02755	COG0560	Phosphoserine phosphatase
N900_02765	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
N900_02770	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N900_02775	COG1022	Amp-dependent synthetase and ligase
N900_02790	COG3250	beta-galactosidase activity
N900_02795	COG1609	Transcriptional regulator
N900_02800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N900_02815	COG0189	ligase activity
N900_02815	COG0569	domain protein
N900_02825	COG0456	acetyltransferase
N900_02835	COG2171	N-acyltransferase activity
N900_02840	COG3141	response to X-ray
N900_02855	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
N900_02860	COG1074	ATP-dependent DNA helicase activity
N900_02865	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N900_02880	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
N900_02880	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
N900_02890	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
N900_02895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
N900_02900	COG2166	iron-sulfur cluster assembly
N900_02905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N900_02910	COG0693	protein deglycase activity
N900_02915	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N900_02920	COG3248	Nucleoside-binding outer membrane protein
N900_02930	COG1595	DNA-templated transcription, initiation
N900_02940	COG2211	Major facilitator Superfamily
N900_02945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N900_02955	COG2813	Specifically methylates the guanine in position
N900_02960	COG0271	Belongs to the BolA IbaG family
N900_02965	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
N900_02970	COG1805	sodium ion transport
N900_02975	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
N900_02980	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
N900_02985	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
N900_02990	COG2871	sodium ion transport
N900_02995	COG1477	protein flavinylation
N900_03005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N900_03025	COG3328	transposase activity
N900_03030	COG3706	GGDEF domain
N900_03030	COG4251	negative regulation of phosphorylation
N900_03030	COG2203	Gaf domain
N900_03030	COG5001	Diguanylate cyclase
N900_03035	COG0733	neurotransmitter:sodium symporter activity
N900_03045	COG0189	ligase activity
N900_03050	COG0189	ligase activity
N900_03050	COG4067	protein conserved in archaea
N900_03055	COG2195	Cleaves the N-terminal amino acid of tripeptides
N900_03060	COG2252	PERMEase
N900_03065	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
N900_03080	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N900_03085	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
N900_03090	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
N900_03095	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N900_03095	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N900_03110	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
N900_03115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N900_03120	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N900_03125	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N900_03135	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
N900_03140	COG0024	Methionine aminopeptidase
N900_03145	COG0052	Belongs to the universal ribosomal protein uS2 family
N900_03150	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
N900_03155	COG0528	UMP kinase activity
N900_03160	COG0233	cytoplasmic translational termination
N900_03165	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N900_03170	COG0575	Belongs to the CDS family
N900_03175	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
N900_03180	COG0750	zinc metalloprotease
N900_03190	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
N900_03195	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N900_03200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N900_03205	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N900_03210	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N900_03215	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N900_03225	COG0825	malonyl-CoA metabolic process
N900_03230	COG0037	tRNA processing
N900_03240	COG3479	Phenolic acid decarboxylase
N900_03245	COG0347	Belongs to the P(II) protein family
N900_03255	COG0741	lytic transglycosylase activity
N900_03255	COG1388	LysM domain
N900_03260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N900_03265	COG2226	methyltransferase
N900_03270	COG0328	RNA-DNA hybrid ribonuclease activity
N900_03275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N900_03285	COG1960	acyl-CoA dehydrogenase activity
N900_03290	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
N900_03295	COG0121	glutamine amidotransferase
N900_03300	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N900_03305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
N900_03310	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
N900_03315	COG3706	GGDEF domain
N900_03320	COG1187	pseudouridine synthase activity
N900_03325	COG2840	Smr protein MutS2
N900_03340	COG3735	TraB family
N900_03355	COG2608	mercury ion transmembrane transporter activity
N900_03355	COG2217	Heavy metal translocating P-type atpase
N900_03360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N900_03375	COG1629	transport
N900_03375	COG4774	siderophore transport
N900_03380	COG2375	cellular response to nickel ion
N900_03385	COG2226	methyltransferase
N900_03385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N900_03385	COG3433	isochorismatase activity
N900_03420	COG0784	Response regulator, receiver
N900_03420	COG0835	chemotaxis
N900_03425	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N900_03430	COG1815	bacterial-type flagellum-dependent cell motility
N900_03435	COG1558	bacterial-type flagellum-dependent cell motility
N900_03440	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
N900_03445	COG1749	Flagellar hook protein flgE
N900_03450	COG4787	bacterial-type flagellum-dependent cell motility
N900_03455	COG4786	Flagellar basal body rod
N900_03460	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
N900_03465	COG1706	bacterial-type flagellum-dependent cell motility
N900_03470	COG1705	Flagellar rod assembly protein muramidase FlgJ
N900_03470	COG3951	Flagellar rod assembly protein muramidase FlgJ
N900_03485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N900_03490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N900_03520	COG0012	GTP binding
N900_03525	COG0193	aminoacyl-tRNA hydrolase activity
N900_03530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N900_03535	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
N900_03540	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
N900_03545	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
N900_03550	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
N900_03555	COG2890	protein-(glutamine-N5) methyltransferase activity
N900_03560	COG3094	Invasion gene expression up-regulator, SirB
N900_03565	COG2912	Transglutaminase-like superfamily
N900_03570	COG2877	3-deoxy-8-phosphooctulonate synthase activity
N900_03575	COG0737	Belongs to the 5'-nucleotidase family
N900_03580	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N900_03585	COG2233	PERMEase
N900_03605	COG1393	Belongs to the ArsC family
N900_03610	COG4783	chaperone-mediated protein folding
N900_03630	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N900_03640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N900_03645	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
N900_03655	COG1876	peptidase activity
N900_03660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N900_03665	COG1393	Belongs to the ArsC family
N900_03685	COG2837	iron assimilation
N900_03690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N900_03695	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N900_03700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N900_03705	COG1334	flagellar protein FlaG
N900_03710	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
N900_03720	COG1516	flagellar protein fliS
N900_03725	COG2204	response regulator
N900_03730	COG4191	Histidine kinase
N900_03735	COG2204	response regulator
N900_03740	COG1677	Flagellar hook-basal body complex protein FliE
N900_03750	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N900_03755	COG1317	bacterial-type flagellum organization
N900_03775	COG1580	Controls the rotational direction of flagella during chemotaxis
N900_03800	COG1987	bacterial-type flagellum assembly
N900_03805	COG1684	flagellar biosynthetic protein fliR
N900_03820	COG2890	protein-(glutamine-N5) methyltransferase activity
N900_03825	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
N900_03830	COG2860	membrane
N900_03835	COG3101	peptidyl-lysine hydroxylation
N900_03845	COG0431	NADPH-dependent FMN reductase
N900_03850	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
N900_03850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N900_03855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N900_03860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N900_03865	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N900_03870	COG0735	belongs to the Fur family
N900_03880	COG0583	DNA-binding transcription factor activity
N900_03890	COG1346	cytolysis
N900_03905	COG0596	Alpha beta hydrolase
N900_03910	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
N900_03915	COG0033	Phosphoglucomutase
N900_03925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
N900_03930	COG0372	Belongs to the citrate synthase family
N900_03935	COG2009	succinate dehydrogenase
N900_03940	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
N900_03945	COG1053	succinate dehydrogenase
N900_03955	COG0567	Dehydrogenase, E1 component
N900_03960	COG0508	dehydrogenase complex catalyzes the overall conversion of
N900_03965	COG0045	succinate-CoA ligase (ADP-forming) activity
N900_03975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N900_03980	COG1121	(ABC) transporter
N900_03985	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
N900_03990	COG4977	sequence-specific DNA binding
N900_03995	COG1918	ferrous iron import across plasma membrane
N900_04015	COG0018	arginyl-trna synthetase
N900_04025	COG1025	Belongs to the peptidase M16 family
N900_04030	COG2062	phosphohistidine phosphatase, SixA
N900_04045	COG0455	bacterial-type flagellum organization
N900_04060	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
N900_04065	COG0643	Histidine kinase
N900_04065	COG2198	Histidine kinase
N900_04070	COG2201	protein-glutamate methylesterase activity
N900_04075	COG1192	Involved in chromosome partitioning
N900_04085	COG0835	chemotaxis
N900_04095	COG4133	protoheme IX ABC transporter activity
N900_04100	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N900_04105	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N900_04115	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
N900_04120	COG1138	Cytochrome C-type biogenesis protein
N900_04125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N900_04130	COG3088	subunit of a heme lyase
N900_04130	COG4235	cytochrome complex assembly
N900_04140	COG2853	Lipoprotein
N900_04160	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
N900_04165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N900_04170	COG0123	including yeast histone deacetylase and acetoin utilization protein
N900_04185	COG3083	sulfuric ester hydrolase activity
N900_04195	COG3081	Nucleoid-associated protein
N900_04205	COG1757	Na H antiporter
N900_04210	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N900_04215	COG2095	MarC family integral membrane protein
N900_04220	COG1012	belongs to the aldehyde dehydrogenase family
N900_04220	COG1454	alcohol dehydrogenase
N900_04230	COG0659	secondary active sulfate transmembrane transporter activity
N900_04235	COG1530	ribonuclease E activity
N900_04245	COG0564	pseudouridine synthase activity
N900_04250	COG0424	maF-like protein
N900_04255	COG1399	metal-binding, possibly nucleic acid-binding protein
N900_04260	COG0333	Belongs to the bacterial ribosomal protein bL32 family
N900_04265	COG0416	fatty acid biosynthetic process
N900_04270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N900_04275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N900_04280	COG1028	Short-chain dehydrogenase reductase Sdr
N900_04285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N900_04290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N900_04295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N900_04300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N900_04305	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N900_04315	COG0084	hydrolase, TatD family'
N900_04320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N900_04320	COG1263	PTS System
N900_04330	COG0733	neurotransmitter:sodium symporter activity
N900_04345	COG4667	esterase of the alpha-beta hydrolase superfamily
N900_04355	COG1940	carbohydrate kinase activity
N900_04360	COG0835	chemotaxis
N900_04360	COG0784	Response regulator, receiver
N900_04375	COG2226	methyltransferase
N900_04385	COG0676	glucose-6-phosphate 1-epimerase activity
N900_04390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N900_04395	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N900_04405	COG3139	Protein of unknown function (DUF1315)
N900_04410	COG0252	asparaginase activity
N900_04415	COG0616	signal peptide processing
N900_04420	COG0446	pyridine nucleotide-disulphide oxidoreductase
N900_04420	COG1902	pentaerythritol trinitrate reductase activity
N900_04425	COG0788	formyltetrahydrofolate deformylase activity
N900_04435	COG1199	ATP-dependent helicase activity
N900_04440	COG1214	PFAM Peptidase M22, glycoprotease
N900_04455	COG0596	Alpha beta hydrolase
N900_04460	COG0318	PFAM AMP-dependent synthetase and ligase
N900_04465	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
N900_04485	COG0232	Belongs to the dGTPase family. Type 2 subfamily
N900_04490	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
N900_04495	COG0436	Aminotransferase
N900_04500	COG1169	isochorismate synthase
N900_04505	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
N900_04510	COG0596	Alpha beta hydrolase
N900_04520	COG1441	menaquinone biosynthetic process
N900_04530	COG3135	benzoate transporter
N900_04535	COG1396	sequence-specific DNA binding
N900_04540	COG0840	transmembrane signaling receptor activity
N900_04550	COG0477	Major facilitator Superfamily
N900_04570	COG3015	lipoprotein NlpE involved in copper resistance
N900_04575	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
N900_04580	COG2894	cell division
N900_04585	COG0850	regulation of cytokinetic process
N900_04590	COG3100	YcgL domain-containing protein
N900_04595	COG2951	lytic endotransglycosylase activity
N900_04610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N900_04615	COG3325	Belongs to the glycosyl hydrolase 18 family
N900_04615	COG3469	chitinase activity
N900_04620	COG3005	denitrification pathway
N900_04625	COG0243	molybdopterin cofactor binding
N900_04645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N900_04655	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N900_04690	COG4589	Belongs to the CDS family
N900_04700	COG3300	MHYT domain
N900_04700	COG5001	Diguanylate cyclase
N900_04715	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
N900_04720	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N900_04725	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
N900_04730	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
N900_04740	COG4191	Histidine kinase
N900_04750	COG0544	peptidyl-prolyl cis-trans isomerase activity
N900_04760	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
N900_04765	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
N900_04770	COG0776	regulation of translation
N900_04775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N900_04780	COG1555	photosystem II stabilization
N900_04785	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
N900_04790	COG0539	negative regulation of cytoplasmic translation
N900_04795	COG0776	regulation of translation
N900_04800	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
N900_04805	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
N900_04810	COG0284	orotidine-5'-phosphate decarboxylase activity
N900_04830	COG0583	DNA-binding transcription factor activity
N900_04840	COG0686	Belongs to the AlaDH PNT family
N900_04850	COG1674	ftsk spoiiie
N900_04855	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
N900_04860	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
N900_04865	COG2186	Transcriptional regulator
N900_04880	COG0537	adenosine 5'-monophosphoramidase activity
N900_04910	COG1252	NADH dehydrogenase
N900_04930	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N900_04940	COG4591	ABC-type transport system involved in lipoprotein release permease component
N900_04945	COG1136	(ABC) transporter
N900_04950	COG4591	ABC-type transport system involved in lipoprotein release permease component
N900_04960	COG2333	competence protein COMEC
N900_04960	COG0658	competence protein
N900_04965	COG1132	(ABC) transporter
N900_04970	COG1663	tetraacyldisaccharide 4'-kinase activity
N900_04980	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
N900_04985	COG2719	SpoVR family
N900_04990	COG2718	Belongs to the UPF0229 family
N900_04995	COG2766	serine protein kinase
N900_05000	COG3013	Belongs to the UPF0304 family
N900_05010	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
N900_05015	COG0840	transmembrane signaling receptor activity
N900_05025	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
N900_05045	COG4215	(ABC) transporter
N900_05050	COG4160	amino acid transport
N900_05055	COG0708	Exodeoxyribonuclease III
N900_05060	COG0840	transmembrane signaling receptor activity
N900_05070	COG3923	Primosomal replication protein n
N900_05075	COG0730	response to heat
N900_05080	COG1199	ATP-dependent helicase activity
N900_05085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
N900_05090	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
N900_05100	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
N900_05105	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N900_05110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N900_05115	COG0215	cysteine-tRNA ligase activity
N900_05120	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
N900_05125	COG0632	four-way junction helicase activity
N900_05130	COG2255	four-way junction helicase activity
N900_05135	COG1271	oxidase subunit
N900_05140	COG1294	oxidase, subunit
N900_05145	COG4890	Cyd operon protein YbgT
N900_05150	COG3790	cyd operon protein YbgE
N900_05155	COG0824	Thioesterase
N900_05160	COG0811	peptide transport
N900_05175	COG0823	Involved in the tonB-independent uptake of proteins
N900_05180	COG2885	chlorophyll binding
N900_05190	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N900_05200	COG0784	Response regulator, receiver
N900_05200	COG5002	protein histidine kinase activity
N900_05210	COG1482	cell wall glycoprotein biosynthetic process
N900_05215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N900_05215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N900_05215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N900_05220	COG2207	Transcriptional regulator
N900_05230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N900_05235	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N900_05240	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N900_05250	COG1012	belongs to the aldehyde dehydrogenase family
N900_05255	COG3284	Transcriptional regulator
N900_05260	COG4628	conserved protein (DUF2132)
N900_05270	COG0415	Belongs to the DNA photolyase family
N900_05345	COG0488	(ABC) transporter
N900_05385	COG3941	tape measure
N900_05410	COG2003	Belongs to the UPF0758 family
N900_05420	COG4409	exo-alpha-(2->6)-sialidase activity
N900_05425	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N900_05430	COG1940	carbohydrate kinase activity
N900_05435	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
N900_05440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N900_05445	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
N900_05450	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
N900_05455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N900_05460	COG1737	Transcriptional regulator
N900_05465	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
N900_05470	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
N900_05490	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
N900_05510	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
N900_05530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N900_05535	COG0582	viral genome integration into host DNA
N900_05540	COG0582	viral genome integration into host DNA
N900_05555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N900_05565	COG3008	intermembrane lipid transfer
N900_05565	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
N900_05570	COG2995	paraquat-inducible protein a
N900_05575	COG0668	transmembrane transport
N900_05595	COG1309	transcriptional regulator
N900_05600	COG1012	belongs to the aldehyde dehydrogenase family
N900_05625	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N900_05630	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
N900_05635	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
N900_05640	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
N900_05650	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N900_05660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N900_05670	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N900_05675	COG0297	glycogen (starch) synthase activity
N900_05695	COG3070	regulator of competence-specific genes
N900_05700	COG1609	Transcriptional regulator
N900_05705	COG3381	protein complex oligomerization
N900_05710	COG0745	RESPONSE REGULATOR receiver
N900_05715	COG1434	Gram-negative-bacterium-type cell wall biogenesis
N900_05720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N900_05725	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
N900_05730	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
N900_05735	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
N900_05750	COG1032	radical SAM domain protein
N900_05760	COG0612	Peptidase, M16
N900_05775	COG0583	DNA-binding transcription factor activity
N900_05780	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N900_05790	COG2350	Protein conserved in bacteria
N900_05795	COG1607	acyl-coa hydrolase
N900_05800	COG2917	probably involved in intracellular septation
N900_05810	COG1434	Gram-negative-bacterium-type cell wall biogenesis
N900_05815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N900_05825	COG2116	formate transmembrane transporter activity
N900_05835	COG4459	periplasmic nitrate reductase
N900_05840	COG3005	denitrification pathway
N900_05845	COG0243	molybdopterin cofactor binding
N900_05865	COG1227	inorganic diphosphatase activity
N900_05880	COG4172	Belongs to the ABC transporter superfamily
N900_05890	COG4171	peptide transport system, permease
N900_05895	COG4168	peptide transport system, permease
N900_05905	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
N900_05910	COG1842	Phage shock protein A
N900_05925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N900_05940	COG2818	Glycosylase
N900_05945	COG0626	cystathionine gamma-synthase activity
N900_05955	COG0733	neurotransmitter:sodium symporter activity
N900_05960	COG0564	pseudouridine synthase activity
N900_05965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N900_05970	COG4136	ATPase activity
N900_05975	COG4135	transport system, permease component
N900_05980	COG4134	Bacterial extracellular solute-binding protein
N900_05990	COG3313	Fe-S protein
N900_06000	COG0842	Transport permease protein
N900_06005	COG1131	(ABC) transporter
N900_06010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N900_06015	COG0814	amino acid
N900_06030	COG2239	Acts as a magnesium transporter
N900_06080	COG0840	transmembrane signaling receptor activity
N900_06095	COG2203	Gaf domain
N900_06095	COG3706	GGDEF domain
N900_06095	COG4251	negative regulation of phosphorylation
N900_06095	COG5001	Diguanylate cyclase
N900_06100	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
N900_06120	COG1061	Type III restriction enzyme res subunit
N900_06125	COG1187	pseudouridine synthase activity
N900_06130	COG2814	Major facilitator Superfamily
N900_06140	COG0702	epimerase
N900_06145	COG0534	Mate efflux family protein
N900_06150	COG4181	ATPase activity
N900_06165	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
N900_06175	COG1748	Saccharopine dehydrogenase
N900_06180	COG0019	diaminopimelate decarboxylase activity
N900_06190	COG1538	Outer membrane efflux protein
N900_06210	COG0583	DNA-binding transcription factor activity
N900_06220	COG1451	nucleotide metabolic process
N900_06225	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
N900_06235	COG3063	Type IV pilus biogenesis stability protein PilW
N900_06240	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
N900_06260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N900_06275	COG3290	protein histidine kinase activity
N900_06280	COG4565	transcriptional regulatory protein
N900_06290	COG0835	chemotaxis
N900_06290	COG0784	Response regulator, receiver
N900_06305	COG0745	RESPONSE REGULATOR receiver
N900_06305	COG3706	GGDEF domain
N900_06335	COG1085	galactose-1-phosphate uridylyltransferase
N900_06340	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
N900_06345	COG2017	converts alpha-aldose to the beta-anomer
N900_06350	COG3706	GGDEF domain
N900_06355	COG2200	EAL domain
N900_06355	COG2199	diguanylate cyclase activity
N900_06370	COG3527	Alpha-acetolactate decarboxylase
N900_06375	COG3527	Alpha-acetolactate decarboxylase
N900_06390	COG0753	catalase activity
N900_06410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N900_06420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N900_06460	COG1271	oxidase subunit
N900_06465	COG1294	oxidase, subunit
N900_06470	COG4591	ABC-type transport system involved in lipoprotein release permease component
N900_06470	COG1136	(ABC) transporter
N900_06475	COG1136	(ABC) transporter
N900_06475	COG0577	efflux transmembrane transporter activity
N900_06480	COG0577	efflux transmembrane transporter activity
N900_06480	COG1136	(ABC) transporter
N900_06500	COG0583	DNA-binding transcription factor activity
N900_06505	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
N900_06510	COG2723	6-phospho-beta-galactosidase activity
N900_06515	COG1609	Transcriptional regulator
N900_06520	COG0251	oxidation-reduction process
N900_06525	COG2731	YhcH YjgK YiaL family protein
N900_06530	COG0584	glycerophosphoryl diester phosphodiesterase
N900_06535	COG1349	DNA-binding transcription factor activity
N900_06540	COG3842	ATPase activity
N900_06545	COG0395	ABC-type sugar transport system, permease component
N900_06550	COG1175	transmembrane transport
N900_06565	COG0811	peptide transport
N900_06570	COG0811	peptide transport
N900_06575	COG0848	biopolymer transport protein
N900_06580	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
N900_06590	COG1793	dna ligase
N900_06600	COG0534	Mate efflux family protein
N900_06620	COG0791	NLP P60 protein
N900_06625	COG0840	transmembrane signaling receptor activity
N900_06640	COG1940	carbohydrate kinase activity
N900_06670	COG0746	molybdenum cofactor guanylyltransferase activity
N900_06675	COG3842	ATPase activity
N900_06680	COG4662	Binding-protein-dependent transport system inner membrane component
N900_06690	COG2204	response regulator
N900_06695	COG3852	Histidine kinase
N900_06700	COG0488	(ABC) transporter
N900_06705	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N900_06735	COG3383	formate dehydrogenase (NAD+) activity
N900_06735	COG0243	molybdopterin cofactor binding
N900_06740	COG0437	4 iron, 4 sulfur cluster binding
N900_06755	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N900_06765	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
N900_06780	COG2996	Protein conserved in bacteria
N900_06785	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
N900_06785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
N900_06790	COG3008	intermembrane lipid transfer
N900_06795	COG2995	paraquat-inducible protein a
N900_06800	COG1132	(ABC) transporter
N900_06805	COG1956	GAF domain-containing protein
N900_06810	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
N900_06825	COG0308	aminopeptidase N
N900_06840	COG0167	dihydroorotate dehydrogenase activity
N900_06850	COG0116	Belongs to the methyltransferase superfamily
N900_06850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
N900_06870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N900_06875	COG1067	ATP-dependent peptidase activity
N900_06880	COG3120	sequence-specific DNA binding
N900_06895	COG3328	transposase activity
N900_06980	COG1476	TRANSCRIPTIONal
N900_07000	COG1476	TRANSCRIPTIONal
N900_07035	COG4128	Pfam Zonular occludens toxin
N900_07055	COG2994	toxin metabolic process
N900_07080	COG0784	Response regulator, receiver
N900_07080	COG2205	protein histidine kinase activity
N900_07095	COG3278	Belongs to the heme-copper respiratory oxidase family
N900_07110	COG2010	Cytochrome c
N900_07120	COG2217	Heavy metal translocating P-type atpase
N900_07135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N900_07140	COG0589	response to stress
N900_07145	COG0037	tRNA processing
N900_07165	COG3842	ATPase activity
N900_07170	COG1176	ABC-type spermidine putrescine transport system, permease component I
N900_07175	COG1177	transmembrane transport
N900_07180	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
N900_07185	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
N900_07200	COG1115	amino acid carrier protein
N900_07205	COG1280	lysine exporter protein (LysE YggA)
N900_07230	COG3501	Rhs element vgr protein
N900_07240	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
N900_07245	COG0840	transmembrane signaling receptor activity
N900_07250	COG2814	Major facilitator Superfamily
N900_07255	COG1566	PFAM secretion protein HlyD family protein
N900_07260	COG1538	Outer membrane efflux protein
N900_07270	COG0513	Belongs to the DEAD box helicase family
N900_07280	COG0840	transmembrane signaling receptor activity
N900_07285	COG3290	protein histidine kinase activity
N900_07285	COG0840	transmembrane signaling receptor activity
N900_07290	COG0835	chemotaxis
N900_07295	COG2201	protein-glutamate methylesterase activity
N900_07305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N900_07315	COG2198	Histidine kinase
N900_07315	COG0643	Histidine kinase
N900_07335	COG2076	Multidrug Resistance protein
N900_07340	COG0415	Belongs to the DNA photolyase family
N900_07345	COG0477	Major facilitator Superfamily
N900_07350	COG0583	DNA-binding transcription factor activity
N900_07355	COG0095	Lipoate-protein ligase
N900_07360	COG0443	Heat shock 70 kDa protein
N900_07370	COG1643	Atp-dependent helicase
N900_07400	COG0443	Heat shock 70 kDa protein
N900_07405	COG0443	Heat shock 70 kDa protein
N900_07410	COG3706	GGDEF domain
N900_07440	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
N900_07445	COG0602	queuosine metabolic process
N900_07450	COG0561	phosphatase activity
N900_07460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N900_07465	COG4597	amino acid ABC transporter
N900_07470	COG0765	amino acid transport
N900_07475	COG1126	abc transporter atp-binding protein
N900_07480	COG0670	Belongs to the BI1 family
N900_07485	COG2920	part of a sulfur-relay system
N900_07490	COG1254	Belongs to the acylphosphatase family
N900_07495	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
N900_07500	COG3706	GGDEF domain
N900_07515	COG3437	response regulator, receiver
N900_07520	COG0625	glutathione transferase activity
N900_07530	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
N900_07545	COG2195	Cleaves the N-terminal amino acid of tripeptides
N900_07575	COG0372	Belongs to the citrate synthase family
N900_07580	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
N900_07585	COG2186	Transcriptional regulator
N900_07620	COG1129	ABC transporter
N900_07645	COG0745	RESPONSE REGULATOR receiver
N900_07650	COG2205	protein histidine kinase activity
N900_07655	COG3713	MltA-interacting MipA family protein
N900_07660	COG2990	Protein conserved in bacteria
N900_07670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N900_07670	COG4191	Histidine kinase
N900_07675	COG0471	metal ion transport
N900_07685	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N900_07700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N900_07705	COG3283	Transcriptional regulator of aromatic amino acids metabolism
N900_07710	COG3768	UPF0283 membrane protein
N900_07715	COG3106	COG3106 Predicted ATPase
N900_07730	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N900_07735	COG0494	nUDIX hydrolase
N900_07740	COG0814	amino acid
N900_07745	COG1760	l-serine dehydratase
N900_07750	COG0720	synthase
N900_07760	COG0017	Asparaginyl-tRNA synthetase
N900_07765	COG0351	phosphomethylpyrimidine kinase
N900_07770	COG3437	response regulator, receiver
N900_07770	COG2770	Histidine kinase
N900_07780	COG1448	Aminotransferase
N900_07795	COG0840	transmembrane signaling receptor activity
N900_07800	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
N900_07805	COG2943	transferase activity, transferring hexosyl groups
N900_07810	COG1609	Transcriptional regulator
N900_07815	COG3394	polysaccharide catabolic process
N900_07820	COG1486	melibiose metabolic process
N900_07825	COG1447	Phosphotransferase system cellobiose-specific component IIA
N900_07835	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N900_07840	COG0726	polysaccharide deacetylase
N900_07845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N900_07850	COG1846	Transcriptional regulator
N900_07875	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
N900_07890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N900_07895	COG3108	Peptidase M15
N900_07900	COG2989	Protein conserved in bacteria
N900_07925	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N900_07935	COG2814	Major facilitator Superfamily
N900_07955	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N900_07960	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N900_07965	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N900_08010	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
N900_08015	COG4139	cobalamin transport
N900_08020	COG2988	succinylglutamate desuccinylase activity
N900_08035	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
N900_08040	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
N900_08050	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N900_08060	COG2925	Exonuclease
N900_08070	COG1346	cytolysis
N900_08075	COG0295	cytidine deaminase activity
N900_08085	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
N900_08090	COG0500	methyltransferase
N900_08105	COG0776	regulation of translation
N900_08110	COG0072	phenylalanine-tRNA ligase activity
N900_08110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N900_08115	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
N900_08125	COG0745	RESPONSE REGULATOR receiver
N900_08125	COG3706	GGDEF domain
N900_08155	COG0322	excinuclease ABC activity
N900_08160	COG2197	response regulator
N900_08165	COG0417	DNA replication proofreading
N900_08170	COG5001	Diguanylate cyclase
N900_08180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N900_08200	COG1228	amidohydrolase
N900_08205	COG0010	Belongs to the arginase family
N900_08210	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
N900_08215	COG2986	histidine ammonia-lyase
N900_08235	COG0277	FAD linked oxidase domain protein
N900_08235	COG0247	lactate metabolic process
N900_08250	COG2885	chlorophyll binding
N900_08270	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
N900_08280	COG0281	malic enzyme
N900_08290	COG2949	membrane
N900_08300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N900_08310	COG0492	ferredoxin-NADP+ reductase activity
N900_08315	COG4988	ABC transporter
N900_08320	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
N900_08325	COG1187	pseudouridine synthase activity
N900_08330	COG0009	L-threonylcarbamoyladenylate synthase
N900_08335	COG0613	PHP domain protein
N900_08345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N900_08350	COG0512	Glutamine amidotransferase of anthranilate synthase
N900_08355	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N900_08360	COG0135	phosphoribosylanthranilate isomerase activity
N900_08360	COG0134	indole-3-glycerol-phosphate synthase activity
N900_08365	COG0133	tryptophan synthase activity
N900_08370	COG0159	tryptophan synthase activity
N900_08380	COG1435	thymidine kinase activity
N900_08385	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
N900_08390	COG1801	Protein of unknown function DUF72
N900_08395	COG4106	trans-aconitate 2-methyltransferase activity
N900_08400	COG0500	methyltransferase
N900_08405	COG0189	ligase activity
N900_08405	COG4067	protein conserved in archaea
N900_08420	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
N900_08430	COG3852	Histidine kinase
N900_08445	COG3070	regulator of competence-specific genes
N900_08455	COG2431	L-lysine efflux transmembrane transporter activity
N900_08465	COG0076	glutamate decarboxylase activity
N900_08470	COG1737	Transcriptional regulator
N900_08475	COG1012	belongs to the aldehyde dehydrogenase family
N900_08475	COG1454	alcohol dehydrogenase
N900_08480	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N900_08490	COG0542	response to heat
N900_08495	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
N900_08500	COG1278	Cold shock
N900_08510	COG1187	pseudouridine synthase activity
N900_08515	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N900_08515	COG0140	phosphoribosyl-ATP diphosphatase activity
N900_08520	COG0107	imidazoleglycerol-phosphate synthase activity
N900_08525	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
N900_08530	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N900_08535	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
N900_08535	COG0131	Imidazoleglycerol-phosphate dehydratase
N900_08540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N900_08545	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N900_08550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N900_08555	COG1757	Na H antiporter
N900_08560	COG2916	Histone family protein nucleoid-structuring protein H-NS
N900_08565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N900_08570	COG0482	sulfurtransferase activity
N900_08575	COG2915	High frequency lysogenization protein hflD homolog
N900_08580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N900_08590	COG2268	Band 7 protein
N900_08600	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
N900_08615	COG0300	oxidoreductase activity
N900_08625	COG0501	Belongs to the peptidase M48B family
N900_08635	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
N900_08640	COG2226	methyltransferase
N900_08645	COG0156	8-amino-7-oxononanoate synthase activity
N900_08650	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
N900_08655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N900_08660	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
N900_08665	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N900_08670	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
N900_08680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N900_08685	COG2203	Gaf domain
N900_08685	COG2199	diguanylate cyclase activity
N900_08695	COG4120	Belongs to the binding-protein-dependent transport system permease family
N900_08705	COG4628	conserved protein (DUF2132)
N900_08710	COG3092	negative regulation of chromosome organization
N900_08715	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N900_08720	COG0280	phosphate acetyltransferase
N900_08720	COG0857	belongs to the CobB CobQ family
N900_08725	COG0435	Glutathione S-transferase
N900_08730	COG4608	Belongs to the ABC transporter superfamily
N900_08735	COG0444	Belongs to the ABC transporter superfamily
N900_08740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N900_08745	COG0601	transmembrane transport
N900_08765	COG2204	response regulator
N900_08770	COG3300	MHYT domain
N900_08770	COG5001	Diguanylate cyclase
N900_08775	COG4191	Histidine kinase
N900_08780	COG5002	protein histidine kinase activity
N900_08790	COG2201	protein-glutamate methylesterase activity
N900_08805	COG0009	L-threonylcarbamoyladenylate synthase
N900_08825	COG1881	PFAM PEBP family protein
N900_08850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N900_08855	COG0640	Transcriptional regulator
N900_08860	COG3706	GGDEF domain
N900_08880	COG1946	Acyl-CoA thioesterase
N900_08885	COG1522	sequence-specific DNA binding
N900_08895	COG0616	signal peptide processing
N900_08900	COG1028	Short-chain dehydrogenase reductase Sdr
N900_08915	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N900_08920	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
N900_08930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N900_08945	COG0745	RESPONSE REGULATOR receiver
N900_08950	COG0583	DNA-binding transcription factor activity
N900_08955	COG0778	Nitroreductase
N900_08960	COG1024	Enoyl-CoA hydratase
N900_08960	COG1250	3-hydroxyacyl-CoA dehydrogenase
N900_08965	COG0183	Belongs to the thiolase family
N900_08990	COG2067	long-chain fatty acid transport protein
N900_09000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N900_09005	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
N900_09010	COG2982	Protein involved in outer membrane biogenesis
N900_09015	COG0572	uridine kinase
N900_09025	COG0489	protein tyrosine kinase activity
N900_09030	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N900_09030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N900_09040	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
N900_09050	COG4109	DRTGG domain
N900_09055	COG2199	diguanylate cyclase activity
N900_09060	COG0314	molybdopterin synthase activity
N900_09065	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
N900_09070	COG0315	cyclic pyranopterin monophosphate synthase activity
N900_09075	COG0521	Mo-molybdopterin cofactor biosynthetic process
N900_09080	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N900_09085	COG0391	Required for morphogenesis under gluconeogenic growth conditions
N900_09090	COG2198	Histidine kinase
N900_09095	COG2204	response regulator
N900_09105	COG0556	nucleotide-excision repair
N900_09120	COG4657	Part of a membrane complex involved in electron transport
N900_09125	COG2878	Part of a membrane complex involved in electron transport
N900_09135	COG4658	electron transport chain
N900_09140	COG4659	FMN binding
N900_09145	COG4660	Part of a membrane complex involved in electron transport
N900_09150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N900_09155	COG0346	lactoylglutathione lyase activity
N900_09175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N900_09180	COG2056	Na+-H+ antiporter family
N900_09185	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
N900_09190	COG1286	toxin biosynthetic process
N900_09195	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
N900_09200	COG0285	dihydrofolate synthase activity
N900_09205	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
N900_09210	COG0101	tRNA pseudouridine synthase activity
N900_09225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N900_09230	COG2190	(PTS) system
N900_09230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N900_09230	COG1263	PTS System
N900_09235	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N900_09240	COG1940	carbohydrate kinase activity
N900_09240	COG1846	Transcriptional regulator
N900_09245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N900_09245	COG4651	solute:proton antiporter activity
N900_09250	COG0367	asparagine synthase
N900_09265	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N900_09270	COG0563	adenylate kinase activity
N900_09275	COG0326	Molecular chaperone. Has ATPase activity
N900_09280	COG3710	Transcriptional regulator
N900_09295	COG0622	Phosphoesterase
N900_09300	COG1090	epimerase
N900_09305	COG0300	oxidoreductase activity
N900_09315	COG3118	belongs to the thioredoxin family
N900_09320	COG0330	HflC and HflK could
N900_09325	COG1585	Membrane protein implicated in regulation of membrane protease activity
N900_09330	COG0789	Transcriptional regulator
N900_09345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N900_09350	COG3115	cell septum assembly
N900_09355	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
N900_09360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N900_09365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N900_09375	COG2190	(PTS) system
N900_09380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N900_09385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N900_09390	COG1702	phosphate starvation-inducible protein PhoH
N900_09395	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
N900_09400	COG4535	Mg2 and Co2 transporter CorC
N900_09405	COG0815	Transfers the fatty acyl group on membrane lipoproteins
N900_09410	COG2888	peptidyl-tyrosine sulfation
N900_09415	COG0495	leucyl-tRNA aminoacylation
N900_09420	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
N900_09425	COG1466	dna polymerase III delta subunit
N900_09430	COG0799	negative regulation of ribosome biogenesis
N900_09435	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
N900_09440	COG0768	penicillin binding
N900_09445	COG0772	Belongs to the SEDS family
N900_09450	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
N900_09455	COG1686	Belongs to the peptidase S11 family
N900_09460	COG2921	Belongs to the UPF0250 family
N900_09465	COG0321	lipoyl(octanoyl) transferase activity
N900_09470	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N900_09480	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N900_09505	COG1596	polysaccharide export
N900_09515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N900_09545	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
N900_09555	COG0438	transferase activity, transferring glycosyl groups
N900_09565	COG1045	serine acetyltransferase
N900_09585	COG0110	maltose O-acetyltransferase activity
N900_09590	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
N900_09595	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
N900_09600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N900_09605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N900_09630	COG0366	Alpha amylase catalytic
N900_09635	COG1263	PTS System
N900_09635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N900_09640	COG1609	Transcriptional regulator
N900_09645	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
N900_09650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N900_09655	COG2011	ABC-type metal ion transport system permease component
N900_09660	COG1464	Belongs to the NlpA lipoprotein family
N900_09665	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
N900_09675	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
N900_09675	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
N900_09685	COG3706	GGDEF domain
N900_09690	COG1611	Belongs to the LOG family
N900_09695	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N900_09700	COG2363	Small membrane protein
N900_09705	COG0583	DNA-binding transcription factor activity
N900_09715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N900_09715	COG0301	tRNA thio-modification
N900_09725	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N900_09730	COG1722	exodeoxyribonuclease VII activity
N900_09735	COG0142	geranyltranstransferase activity
N900_09740	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N900_09745	COG0564	pseudouridine synthase activity
N900_09750	COG3098	single-species biofilm formation
N900_09765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N900_09775	COG1671	Belongs to the UPF0178 family
N900_09780	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
N900_09785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
N900_09790	COG0254	rRNA binding
N900_09795	COG1720	tRNA m6t6A37 methyltransferase activity
N900_09800	COG0442	prolyl-tRNA aminoacylation
N900_09820	COG1943	Transposase
N900_09825	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N900_09825	COG0047	phosphoribosylformylglycinamidine synthase activity
N900_09835	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
N900_09845	COG0590	tRNA wobble adenosine to inosine editing
N900_09850	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
N900_09880	COG0484	heat shock protein binding
N900_09885	COG0443	Heat shock 70 kDa protein
N900_09890	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
N900_09895	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N900_09900	COG0497	DNA recombination
N900_09905	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N900_09910	COG2914	Belongs to the UPF0125 (RnfH) family
N900_09915	COG2867	negative regulation of translational initiation
N900_09920	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
N900_09925	COG0582	viral genome integration into host DNA
N900_09935	COG3064	Membrane
N900_09945	COG0739	heme binding
N900_09975	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
N900_09990	COG1459	type II secretion system
N900_09995	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N900_10015	COG4796	Type ii and iii secretion system protein
N900_10030	COG2165	general secretion pathway protein
N900_10040	COG3710	Transcriptional regulator
N900_10045	COG0840	transmembrane signaling receptor activity
N900_10050	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
N900_10070	COG1012	belongs to the aldehyde dehydrogenase family
N900_10130	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
N900_10135	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
N900_10140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N900_10150	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
N900_10155	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
N900_10160	COG3051	citrate lyase alpha subunit
N900_10165	COG2301	Belongs to the HpcH HpaI aldolase family
N900_10170	COG3052	prosthetic group binding
N900_10175	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
N900_10185	COG3630	sodium ion export across plasma membrane
N900_10190	COG0511	ligase activity, forming carbon-carbon bonds
N900_10190	COG5016	pyruvate
N900_10195	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
N900_10205	COG4565	transcriptional regulatory protein
N900_10220	COG0583	DNA-binding transcription factor activity
N900_10225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N900_10230	COG1115	amino acid carrier protein
N900_10235	COG2015	COG2015, Alkyl sulfatase and related hydrolases
N900_10240	COG0583	DNA-binding transcription factor activity
N900_10250	COG1120	ATPase activity
N900_10255	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N900_10260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N900_10265	COG4592	Periplasmic binding protein
N900_10275	COG1028	Short-chain dehydrogenase reductase Sdr
N900_10280	COG1169	isochorismate synthase
N900_10285	COG1021	2,3-dihydroxybenzoate-AMP ligase
N900_10290	COG1535	isochorismatase
N900_10290	COG3433	isochorismatase activity
N900_10295	COG1584	GPR1 FUN34 yaaH family protein
N900_10310	COG0519	Catalyzes the synthesis of GMP from XMP
N900_10310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N900_10315	COG0517	IMP dehydrogenase activity
N900_10315	COG0516	GMP reductase activity
N900_10320	COG1570	exodeoxyribonuclease VII activity
N900_10335	COG1160	GTP binding
N900_10340	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N900_10345	COG2976	Protein conserved in bacteria
N900_10350	COG0124	histidyl-tRNA synthetase
N900_10355	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
N900_10365	COG0820	rRNA (adenine-C2-)-methyltransferase activity
N900_10370	COG0105	UTP biosynthetic process
N900_10375	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N900_10380	COG2975	iron-sulfur cluster assembly
N900_10385	COG0633	Ferredoxin
N900_10390	COG0443	Heat shock 70 kDa protein
N900_10395	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
N900_10405	COG0822	iron-sulfur transferase activity
N900_10410	COG1104	cysteine desulfurase activity
N900_10415	COG1959	2 iron, 2 sulfur cluster binding
N900_10425	COG0483	inositol monophosphate 1-phosphatase activity
N900_10430	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N900_10435	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N900_10440	COG1862	Preprotein translocase
N900_10445	COG0343	queuine tRNA-ribosyltransferase activity
N900_10450	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
N900_10455	COG0517	IMP dehydrogenase activity
N900_10465	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N900_10470	COG0583	DNA-binding transcription factor activity
N900_10475	COG0450	alkyl hydroperoxide reductase
N900_10480	COG3142	Participates in the control of copper homeostasis
N900_10495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N900_10500	COG0581	inorganic phosphate transmembrane transporter activity
N900_10510	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
N900_10515	COG0248	Ppx GppA phosphatase
N900_10525	COG5002	protein histidine kinase activity
N900_10530	COG0745	RESPONSE REGULATOR receiver
N900_10535	COG2974	May be involved in recombination
N900_10545	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
N900_10585	COG0542	response to heat
N900_10595	COG0564	pseudouridine synthase activity
N900_10600	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N900_10605	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N900_10610	COG0077	Prephenate dehydratase
N900_10610	COG1605	Chorismate mutase
N900_10615	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
N900_10620	COG5001	Diguanylate cyclase
N900_10625	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
N900_10630	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
N900_10640	COG0488	(ABC) transporter
N900_10650	COG1605	Chorismate mutase
N900_10650	COG0287	Prephenate dehydrogenase
N900_10655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
N900_10660	COG3275	phosphorelay sensor kinase activity
N900_10665	COG3279	Response regulator of the LytR AlgR family
N900_10670	COG1472	Belongs to the glycosyl hydrolase 3 family
N900_10675	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
N900_10680	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N900_10695	COG1966	Carbon starvation protein
N900_10700	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
N900_10705	COG1047	Peptidyl-prolyl cis-trans
N900_10710	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
N900_10715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
N900_10720	COG0196	riboflavin kinase activity
N900_10725	COG0728	peptidoglycan biosynthetic process
N900_10730	COG0268	Binds directly to 16S ribosomal RNA
N900_10735	COG0640	Transcriptional regulator
N900_10740	COG0583	DNA-binding transcription factor activity
N900_10745	COG1283	sodium-dependent phosphate transmembrane transporter activity
N900_10750	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
N900_10755	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
N900_10760	COG0730	response to heat
N900_10765	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
N900_10770	COG0494	nUDIX hydrolase
N900_10780	COG3066	DNA modification
N900_10785	COG0667	Aldo Keto reductase
N900_10795	COG2204	response regulator
N900_10800	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
N900_10815	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
N900_10820	COG0513	Belongs to the DEAD box helicase family
N900_10825	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
N900_10935	COG2003	Belongs to the UPF0758 family
N900_10960	COG0714	Associated with various cellular activities
N900_10980	COG0629	single-stranded DNA binding
N900_10995	COG2356	endonuclease I
N900_11035	COG0681	Belongs to the peptidase S26 family
N900_11050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N900_11185	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N900_11200	COG3328	transposase activity
N900_11205	COG3328	transposase activity
N900_11320	COG3153	acetyltransferase
N900_11355	COG4785	May be involved in cell division
N900_11360	COG1185	polyribonucleotide nucleotidyltransferase activity
N900_11365	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
N900_11370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N900_11375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
N900_11380	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
N900_11385	COG0195	Participates in both transcription termination and antitermination
N900_11390	COG0779	Required for maturation of 30S ribosomal subunits
N900_11405	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N900_11410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N900_11415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N900_11420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N900_11425	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
N900_11430	COG1534	Rna-binding protein
N900_11435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N900_11440	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
N900_11445	COG2027	D-alanyl-D-alanine carboxypeptidase
N900_11450	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N900_11455	COG0739	heme binding
N900_11470	COG0316	Belongs to the HesB IscA family
N900_11480	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N900_11485	COG0628	permease
N900_11490	COG2813	Specifically methylates the guanine in position
N900_11500	COG0747	negative chemotaxis
N900_11505	COG0601	transmembrane transport
N900_11510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N900_11515	COG0444	Belongs to the ABC transporter superfamily
N900_11520	COG4608	Belongs to the ABC transporter superfamily
N900_11530	COG2971	BadF BadG BcrA BcrD
N900_11550	COG3842	ATPase activity
N900_11560	COG1840	ABC-type Fe3 transport system, periplasmic component
N900_11565	COG0004	ammonium transporteR
N900_11570	COG0347	Belongs to the P(II) protein family
N900_11575	COG3112	Uncharacterised protein family (UPF0231)
N900_11580	COG1049	propionate catabolic process, 2-methylcitrate cycle
N900_11585	COG1752	Esterase of the alpha-beta hydrolase superfamily
N900_11590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N900_11595	COG1643	Atp-dependent helicase
N900_11605	COG1489	DNA binding
N900_11610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N900_11615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N900_11625	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N900_11630	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
N900_11635	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N900_11640	COG0842	Transport permease protein
N900_11645	COG1131	(ABC) transporter
N900_11655	COG0659	secondary active sulfate transmembrane transporter activity
N900_11660	COG0288	reversible hydration of carbon dioxide
N900_11675	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
N900_11680	COG3107	peptidoglycan biosynthetic process
N900_11685	COG0792	nuclease activity
N900_11690	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
N900_11695	COG2823	Periplasmic or secreted lipoprotein
N900_11700	COG2969	positive regulation of protein catabolic process
N900_11705	COG0625	glutathione transferase activity
N900_11710	COG2857	Cytochrome c1
N900_11715	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N900_11720	COG0723	plastoquinol--plastocyanin reductase activity
N900_11725	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N900_11730	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
N900_11735	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
N900_11745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N900_11750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N900_11755	COG0335	large ribosomal subunit rRNA binding
N900_11760	COG0336	Belongs to the RNA methyltransferase TrmD family
N900_11765	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N900_11770	COG0228	four-way junction DNA binding
N900_11775	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N900_11780	COG4137	Cytochrome C assembly protein
N900_11785	COG4536	flavin adenine dinucleotide binding
N900_11790	COG1854	S-ribosylhomocysteine lyase activity
N900_11795	COG2918	glutathione biosynthetic process
N900_11800	COG0612	Peptidase, M16
N900_11805	COG1238	metal cluster binding
N900_11815	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
N900_11820	COG0511	ligase activity, forming carbon-carbon bonds
N900_11820	COG5016	pyruvate
N900_11825	COG3630	sodium ion export across plasma membrane
N900_11875	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
N900_11880	COG0527	aspartate kinase activity
N900_11885	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N900_11890	COG2137	regulation of response to DNA damage stimulus
N900_11895	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
N900_11905	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N900_11910	COG4208	sulfate ABC transporter
N900_11930	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
N900_11935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N900_11940	COG1388	LysM domain
N900_11940	COG4942	peptidase
N900_11945	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N900_11950	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
N900_11955	COG0585	pseudouridine synthase activity
N900_11960	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
N900_11965	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
N900_11970	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
N900_11975	COG1968	undecaprenyl-diphosphatase activity
N900_11980	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N900_11985	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
N900_11990	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
N900_12000	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
N900_12005	COG0828	Belongs to the bacterial ribosomal protein bS21 family
N900_12010	COG1610	YqeY-like protein
N900_12015	COG0358	DNA primase activity
N900_12020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N900_12030	COG0582	viral genome integration into host DNA
N900_12035	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
N900_12095	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
N900_12100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N900_12105	COG1349	DNA-binding transcription factor activity
N900_12110	COG0469	pyruvate kinase activity
N900_12120	COG0583	DNA-binding transcription factor activity
N900_12125	COG1279	arginine transmembrane transporter activity
N900_12130	COG0668	transmembrane transport
N900_12140	COG0191	fructose-bisphosphate aldolase activity
N900_12150	COG0126	phosphoglycerate kinase activity
N900_12155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N900_12160	COG4771	TonB-dependent receptor
N900_12165	COG0583	DNA-binding transcription factor activity
N900_12180	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N900_12185	COG3091	SprT-like family
N900_12190	COG2356	endonuclease I
N900_12195	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N900_12200	COG0189	ligase activity
N900_12205	COG1678	Uncharacterized ACR, COG1678
N900_12210	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N900_12215	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N900_12235	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
N900_12240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N900_12245	COG0762	integral membrane protein
N900_12250	COG1872	DUF167
N900_12260	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
N900_12265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N900_12270	COG2066	Belongs to the glutaminase family
N900_12275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N900_12280	COG1194	a g-specific adenine glycosylase
N900_12285	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
N900_12290	COG0741	lytic transglycosylase activity
N900_12335	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
N900_12340	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
N900_12345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N900_12350	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
N900_12355	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N900_12360	COG2967	ApaG domain
N900_12365	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N900_12375	COG3610	response to peptide
N900_12380	COG2966	Psort location CytoplasmicMembrane, score
N900_12385	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
N900_12390	COG0211	Belongs to the bacterial ribosomal protein bL27 family
N900_12395	COG0261	This protein binds to 23S rRNA in the presence of protein L20
N900_12400	COG0142	geranyltranstransferase activity
N900_12410	COG0039	L-malate dehydrogenase activity
N900_12415	COG1438	arginine binding
N900_12430	COG0589	response to stress
N900_12450	COG2235	arginine
N900_12455	COG0312	modulator of DNA gyrase
N900_12460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N900_12465	COG3164	Protein of unknown function
N900_12470	COG1530	ribonuclease E activity
N900_12475	COG0424	maF-like protein
N900_12480	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
N900_12485	COG1792	Involved in formation and maintenance of cell shape
N900_12490	COG1077	Cell shape determining protein MreB Mrl
N900_12535	COG1459	type II secretion system
N900_12540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N900_12550	COG3409	Peptidoglycan-binding domain 1 protein
N900_12550	COG3267	Type II secretory pathway component ExeA
N900_12575	COG2199	diguanylate cyclase activity
N900_12575	COG2200	EAL domain
N900_12580	COG0629	single-stranded DNA binding
N900_12595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N900_12605	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N900_12610	COG0527	aspartate kinase activity
N900_12615	COG0646	methionine synthase
N900_12615	COG1410	methionine synthase
N900_12655	COG0175	sulfate reduction
N900_12660	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N900_12665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N900_12685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N900_12690	COG0735	belongs to the Fur family
N900_12705	COG0166	Belongs to the GPI family
N900_12710	COG0432	Pfam Uncharacterised protein family UPF0047
N900_12715	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N900_12720	COG0305	Participates in initiation and elongation during chromosome replication
N900_12730	COG0359	binds to the 23S rRNA
N900_12735	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
N900_12740	COG2965	DNA replication, synthesis of RNA primer
N900_12745	COG0360	Binds together with S18 to 16S ribosomal RNA
N900_12755	COG2906	2 iron, 2 sulfur cluster binding
N900_12760	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N900_12765	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N900_12770	COG0049	tRNA binding
N900_12775	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
N900_12785	COG2923	Belongs to the DsrF TusC family
N900_12790	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
N900_12795	COG2964	Protein conserved in bacteria
N900_12800	COG0545	Peptidyl-prolyl cis-trans isomerase
N900_12810	COG2900	Belongs to the SlyX family
N900_12815	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
N900_12820	COG0330	HflC and HflK could
N900_12825	COG0330	HflC and HflK could
N900_12830	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N900_12835	COG1923	regulation of RNA biosynthetic process
N900_12840	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
N900_12845	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N900_12855	COG0802	atpase or kinase
N900_12860	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N900_12910	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
N900_12915	COG1162	GTPase activity
N900_12920	COG0688	phosphatidylethanolamine metabolic process
N900_12925	COG0471	metal ion transport
N900_12935	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
N900_12940	COG4942	peptidase
N900_12955	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
N900_12960	COG2816	NAD+ diphosphatase activity
N900_12965	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
N900_12970	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N900_12975	COG0085	RNA polymerase activity
N900_12980	COG0222	ribosome binding
N900_12985	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N900_12990	COG0081	regulation of translation
N900_12995	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
N900_13000	COG0250	Participates in transcription elongation, termination and antitermination
N900_13005	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N900_13010	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N900_13035	COG1072	(Pantothenic acid kinase))
N900_13045	COG0812	UDP-N-acetylmuramate dehydrogenase activity
N900_13055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N900_13100	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
N900_13110	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
N900_13115	COG3118	belongs to the thioredoxin family
N900_13120	COG0513	Belongs to the DEAD box helicase family
N900_13125	COG0248	Ppx GppA phosphatase
N900_13130	COG0784	Response regulator, receiver
N900_13130	COG2205	protein histidine kinase activity
N900_13135	COG2814	Major facilitator Superfamily
N900_13150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N900_13155	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
N900_13160	COG0511	ligase activity, forming carbon-carbon bonds
N900_13165	COG0439	Biotin carboxylase
N900_13170	COG2264	protein methyltransferase activity
N900_13175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N900_13180	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
N900_13185	COG1609	Transcriptional regulator
N900_13190	COG0129	dihydroxy-acid dehydratase activity
N900_13195	COG3265	gluconokinase activity
N900_13205	COG0800	Aldolase
N900_13225	COG0840	transmembrane signaling receptor activity
N900_13230	COG1982	Orn Lys Arg decarboxylase major
N900_13235	COG0531	amino acid
N900_13240	COG3710	Transcriptional regulator
N900_13245	COG0789	Transcriptional regulator
N900_13250	COG0138	bifunctional purine biosynthesis protein purh
N900_13255	COG0151	Belongs to the GarS family
N900_13265	COG0776	regulation of translation
N900_13270	COG1253	flavin adenine dinucleotide binding
N900_13275	COG1940	carbohydrate kinase activity
N900_13285	COG3068	Protein conserved in bacteria
N900_13295	COG1573	uracil-dna glycosylase
N900_13300	COG0668	transmembrane transport
N900_13305	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
N900_13310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N900_13355	COG1012	belongs to the aldehyde dehydrogenase family
N900_13355	COG1454	alcohol dehydrogenase
N900_13360	COG0318	PFAM AMP-dependent synthetase and ligase
N900_13390	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
N900_13395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N900_13400	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
N900_13400	COG0662	Cupin 2, conserved barrel domain protein
N900_13405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N900_13440	COG1519	Transferase
N900_13470	COG3642	lipopolysaccharide core region biosynthetic process
N900_13475	COG0859	PFAM glycosyl transferase family 9
N900_13480	COG0463	Glycosyl transferase, family 2
N900_13485	COG0859	PFAM glycosyl transferase family 9
N900_13490	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
N900_13495	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N900_13505	COG0267	Belongs to the bacterial ribosomal protein bL33 family
N900_13510	COG0227	Belongs to the bacterial ribosomal protein bL28 family
N900_13525	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N900_13530	COG1309	transcriptional regulator
N900_13535	COG1560	Kdo2-lipid A biosynthetic process
N900_13540	COG1560	Kdo2-lipid A biosynthetic process
N900_13545	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
N900_13550	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
N900_13555	COG1561	YicC-like family, N-terminal region
N900_13565	COG1263	PTS System
N900_13565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N900_13570	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N900_13590	COG1120	ATPase activity
N900_13595	COG4774	siderophore transport
N900_13600	COG1132	(ABC) transporter
N900_13615	COG0514	ATP-dependent DNA helicase (RecQ)
N900_13620	COG2962	Rard protein
N900_13635	COG1280	lysine exporter protein (LysE YggA)
N900_13640	COG0210	DNA helicase
N900_13650	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
N900_13655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N900_13720	COG2131	deaminase
N900_13730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N900_13740	COG0747	negative chemotaxis
N900_13790	COG1309	transcriptional regulator
N900_13795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N900_13800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N900_13805	COG2960	long-chain fatty acid transporting porin activity
N900_13810	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
N900_13815	COG0583	DNA-binding transcription factor activity
N900_13860	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
N900_13865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N900_13870	COG1739	Uncharacterized protein family UPF0029
N900_13875	COG1250	3-hydroxyacyl-CoA dehydrogenase
N900_13875	COG1024	Enoyl-CoA hydratase
N900_13880	COG0183	Belongs to the thiolase family
N900_13885	COG0583	DNA-binding transcription factor activity
N900_13890	COG2814	Major facilitator Superfamily
N900_13895	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
N900_13900	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N900_13905	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
N900_13910	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
N900_13915	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
N900_13920	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N900_13925	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N900_13935	COG0356	it plays a direct role in the translocation of protons across the membrane
N900_13940	COG3312	ion transport
N900_13945	COG1475	DNA binding
N900_13950	COG1192	Involved in chromosome partitioning
N900_13955	COG0357	Ribosomal RNA small subunit methyltransferase G
N900_13960	COG0445	tRNA wobble uridine modification
N900_13985	COG0217	transcriptional regulatory protein
N900_13990	COG2084	Dehydrogenase
N900_14005	COG2909	trisaccharide binding
N900_14010	COG0058	SHG alpha-glucan phosphorylase activity
N900_14015	COG1640	4-alpha-glucanotransferase
N900_14020	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
N900_14030	COG3501	Rhs element vgr protein
N900_14065	COG0471	metal ion transport
N900_14070	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
N900_14115	COG0671	phosphoesterase, PA-phosphatase related
N900_14120	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
N900_14130	COG1999	signal sequence binding
N900_14145	COG0786	glutamate:sodium symporter activity
N900_14165	COG1566	PFAM secretion protein HlyD family protein
N900_14175	COG3706	GGDEF domain
N900_14190	COG0813	purine-nucleoside phosphorylase activity
N900_14195	COG3272	Protein of unknown function (DUF1722)
N900_14205	COG0415	Belongs to the DNA photolyase family
N900_14210	COG1376	ErfK ybiS ycfS ynhG family protein
N900_14210	COG1388	LysM domain
N900_14220	COG0513	Belongs to the DEAD box helicase family
N900_14225	COG1770	oligopeptidase
N900_14255	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N900_14260	COG0573	inorganic phosphate transmembrane transporter activity
N900_14265	COG0581	inorganic phosphate transmembrane transporter activity
N900_14270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N900_14290	COG0659	secondary active sulfate transmembrane transporter activity
N900_14300	COG0739	heme binding
N900_14305	COG5001	Diguanylate cyclase
N900_14305	COG3300	MHYT domain
N900_14310	COG0583	DNA-binding transcription factor activity
N900_14315	COG2814	Major facilitator Superfamily
N900_14340	COG1301	dicarboxylic acid transport
N900_14350	COG1342	Belongs to the UPF0251 family
N900_14385	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
N900_14390	COG0673	inositol 2-dehydrogenase activity
N900_14400	COG2771	luxR family
N900_14400	COG2200	EAL domain
N900_14405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N900_14415	COG0564	pseudouridine synthase activity
N900_14505	COG3501	Rhs element vgr protein
N900_14520	COG1869	D-ribose catabolic process
N900_14525	COG1129	ABC transporter
N900_14530	COG1172	Belongs to the binding-protein-dependent transport system permease family
N900_14535	COG1879	ABC-type sugar transport system periplasmic component
N900_14540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N900_14545	COG1609	Transcriptional regulator
N900_14555	COG3201	nicotinamide mononucleotide transporter
N900_14560	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
N900_14570	COG0584	glycerophosphoryl diester phosphodiesterase
N900_14575	COG2271	Major facilitator Superfamily
N900_14615	COG0579	oxidoreductase
N900_14625	COG0242	peptide deformylase activity
N900_14635	COG1320	monovalent cation:proton antiporter activity
N900_14640	COG2212	antiporter activity
N900_14660	COG2111	Na H antiporter
N900_14660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N900_14670	COG0589	response to stress
N900_14675	COG0814	amino acid
N900_14680	COG3033	Beta-eliminating lyase
N900_14685	COG3530	Putative quorum-sensing-regulated virulence factor
N900_14700	COG5001	Diguanylate cyclase
N900_14700	COG5002	protein histidine kinase activity
N900_14705	COG1278	Cold shock
N900_14720	COG2304	oxidoreductase activity
N900_14740	COG0714	Associated with various cellular activities
N900_14745	COG0840	transmembrane signaling receptor activity
N900_14760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N900_14765	COG2195	Cleaves the N-terminal amino acid of tripeptides
N900_14775	COG3604	Transcriptional regulator
N900_14780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N900_14780	COG1017	nitric oxide dioxygenase activity
N900_14785	COG1278	Cold shock
N900_14790	COG3036	rescue of stalled ribosome
N900_14815	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
N900_14815	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
N900_14820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N900_14830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N900_14840	COG0516	GMP reductase activity
N900_14865	COG1943	Transposase
N900_14870	COG0513	Belongs to the DEAD box helicase family
N900_14875	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
N900_14880	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N900_14885	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
N900_14890	COG0784	Response regulator, receiver
N900_14890	COG3437	response regulator, receiver
N900_14895	COG4191	Histidine kinase
N900_14895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N900_14905	COG1757	Na H antiporter
N900_14910	COG2814	Major facilitator Superfamily
N900_14920	COG3706	GGDEF domain
N900_14925	COG3240	lipase activity
N900_14935	COG0840	transmembrane signaling receptor activity
N900_14940	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
N900_14945	COG5380	lipid catabolic process
N900_14950	COG4412	M6 family metalloprotease domain protein
N900_14950	COG3291	Pkd domain containing protein
N900_14970	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N900_14975	COG4605	iron ion homeostasis
N900_14980	COG4604	ABC transporter, ATP-binding protein
N900_15000	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N900_15020	COG0745	RESPONSE REGULATOR receiver
N900_15035	COG3623	hexulose-6-phosphate isomerase
N900_15040	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
N900_15045	COG0561	phosphatase activity
N900_15075	COG3038	cytochrome b561
N900_15080	COG0366	Alpha amylase catalytic
N900_15105	COG0745	RESPONSE REGULATOR receiver
N900_15110	COG5002	protein histidine kinase activity
N900_15140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
N900_15155	COG2814	Major facilitator Superfamily
N900_15170	COG1686	Belongs to the peptidase S11 family
N900_15190	COG1943	Transposase
N900_15195	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N900_15195	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N900_15200	COG0509	glycine decarboxylation via glycine cleavage system
N900_15205	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N900_15215	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N900_15225	COG3039	Transposase
N900_15250	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N900_15260	COG0291	Belongs to the bacterial ribosomal protein bL35 family
N900_15265	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
N900_15300	COG1028	Short-chain dehydrogenase reductase Sdr
N900_15335	COG0232	Belongs to the dGTPase family. Type 2 subfamily
N900_15360	COG0494	nUDIX hydrolase
N900_15365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N900_15370	COG3040	lipid binding
N900_15400	COG3328	transposase activity
N900_15405	COG3041	Addiction module toxin RelE StbE family
N900_15465	COG1619	proteins homologs of microcin C7 resistance protein MccF
N900_15510	COG0346	lactoylglutathione lyase activity
N900_15545	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
N900_15550	COG1280	lysine exporter protein (LysE YggA)
N900_15720	COG3549	Plasmid maintenance system killer
N900_15725	COG3093	addiction module antidote protein HigA
N900_15735	COG1619	proteins homologs of microcin C7 resistance protein MccF
N900_15755	COG3040	lipid binding
N900_15820	COG4977	sequence-specific DNA binding
N900_15875	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
N900_15880	COG2944	sequence-specific DNA binding
N900_15895	COG3039	Transposase
N900_15920	COG0346	lactoylglutathione lyase activity
N900_16005	COG1943	Transposase
N900_16065	COG0346	lactoylglutathione lyase activity
N900_16090	COG1328	CTP reductase activity
N900_16095	COG0602	queuosine metabolic process
N900_16105	COG0189	ligase activity
N900_16105	COG4067	protein conserved in archaea
N900_16110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N900_16110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N900_16110	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
N900_16115	COG1105	Belongs to the carbohydrate kinase PfkB family
N900_16120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N900_16120	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N900_16125	COG1609	Transcriptional regulator
N900_16130	COG0420	3'-5' exonuclease activity
N900_16135	COG0419	ATPase involved in DNA repair
N900_16140	COG0784	Response regulator, receiver
N900_16140	COG2205	protein histidine kinase activity
N900_16145	COG0156	8-amino-7-oxononanoate synthase activity
N900_16155	COG0038	chloride channel
N900_16160	COG0523	cobalamin synthesis protein
N900_16170	COG3158	transport of potassium into the cell
N900_16175	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N900_16175	COG1013	pyruvate-flavodoxin oxidoreductase activity
N900_16175	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
N900_16175	COG0674	pyruvate-flavodoxin oxidoreductase activity
N900_16180	COG2205	protein histidine kinase activity
N900_16185	COG0745	RESPONSE REGULATOR receiver
N900_16190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N900_16195	COG0586	Pfam SNARE associated Golgi protein
N900_16205	COG2200	EAL domain
N900_16215	COG3038	cytochrome b561
N900_16225	COG2116	formate transmembrane transporter activity
N900_16235	COG0583	DNA-binding transcription factor activity
N900_16245	COG3593	DNA synthesis involved in DNA repair
N900_16250	COG0737	Belongs to the 5'-nucleotidase family
N900_16265	COG2824	Alkylphosphonate utilization operon protein PhnA
N900_16315	COG3706	GGDEF domain
N900_16330	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
N900_16335	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
N900_16345	COG0745	RESPONSE REGULATOR receiver
N900_16370	COG0023	Translation Initiation Factor
N900_16380	COG1181	Belongs to the D-alanine--D-alanine ligase family
N900_16390	COG0045	succinate-CoA ligase (ADP-forming) activity
N900_16390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N900_16390	COG1042	CoA-binding domain protein
N900_16395	COG0583	DNA-binding transcription factor activity
N900_16400	COG1629	transport
N900_16400	COG4771	TonB-dependent receptor
N900_16415	COG2050	protein possibly involved in aromatic compounds catabolism
N900_16435	COG0625	glutathione transferase activity
N900_16450	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
N900_16455	COG4172	Belongs to the ABC transporter superfamily
N900_16460	COG4239	(ABC) transporter, permease
N900_16465	COG4174	ABC transporter (Permease)
N900_16470	COG4166	transmembrane transport
N900_16515	COG3842	ATPase activity
N900_16525	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N900_16535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N900_16540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N900_16545	COG1011	Hydrolase
N900_16555	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
N900_16560	COG1970	mechanosensitive ion channel activity
N900_16565	COG2759	Belongs to the formate--tetrahydrofolate ligase family
N900_16570	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N900_16570	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N900_16575	COG0302	gtp cyclohydrolase
N900_16585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N900_16595	COG2897	thiosulfate sulfurtransferase activity
N900_16600	COG2390	Transcriptional regulator
N900_16610	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N900_16640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N900_16665	COG0583	DNA-binding transcription factor activity
N900_16670	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
N900_16700	COG0640	Transcriptional regulator
N900_16710	COG0446	pyridine nucleotide-disulphide oxidoreductase
N900_16755	COG1263	PTS System
N900_16755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N900_16765	COG1621	beta-fructofuranosidase activity
N900_16770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N900_16775	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
N900_16785	COG2885	chlorophyll binding
N900_16790	COG0545	Peptidyl-prolyl cis-trans isomerase
N900_16795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N900_16800	COG0840	transmembrane signaling receptor activity
N900_16805	COG3069	C4-dicarboxylate transmembrane transporter activity
N900_16810	COG1760	l-serine dehydratase
N900_16830	COG1609	Transcriptional regulator
N900_16835	COG2197	response regulator
N900_16840	COG3850	Histidine kinase
N900_16845	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
N900_16855	COG0243	molybdopterin cofactor binding
N900_16875	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
N900_16880	COG2197	response regulator
N900_16885	COG3851	Histidine kinase
N900_16890	COG2271	Major facilitator Superfamily
N900_16895	COG1840	ABC-type Fe3 transport system, periplasmic component
N900_16905	COG3842	ATPase activity
N900_16910	COG3243	poly(R)-hydroxyalkanoic acid synthase
N900_16920	COG0183	Belongs to the thiolase family
N900_16930	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N900_16935	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N900_16950	COG3706	GGDEF domain
N900_16955	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N900_16965	COG1979	alcohol dehydrogenase
N900_16980	COG4191	Histidine kinase
N900_16985	COG1840	ABC-type Fe3 transport system, periplasmic component
N900_16990	COG2271	Major facilitator Superfamily
N900_16995	COG0469	pyruvate kinase activity
N900_17000	COG2198	Histidine kinase
N900_17000	COG2205	protein histidine kinase activity
N900_17000	COG0784	Response regulator, receiver
N900_17005	COG1879	ABC-type sugar transport system periplasmic component
N900_17010	COG1803	Methylglyoxal synthase
N900_17015	COG1335	isochorismatase
N900_17020	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
N900_17035	COG0210	DNA helicase
N900_17040	COG1289	transmembrane transporter activity
N900_17070	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
N900_17075	COG4149	molybdate abc transporter
N900_17080	COG0725	ABC transporter, periplasmic molybdate-binding protein
N900_17085	COG1492	cobalamin metabolic process
N900_17130	COG0784	Response regulator, receiver
N900_17130	COG5002	protein histidine kinase activity
N900_17135	COG1879	ABC-type sugar transport system periplasmic component
N900_17175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N900_17180	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N900_17190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
N900_17195	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
N900_17200	COG0247	lactate metabolic process
N900_17205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N900_17210	COG3118	belongs to the thioredoxin family
N900_17240	COG0583	DNA-binding transcription factor activity
N900_17245	COG4160	amino acid transport
N900_17250	COG4215	(ABC) transporter
N900_17255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N900_17260	COG1126	abc transporter atp-binding protein
N900_17270	COG2425	protein containing a von Willebrand factor type A (vWA) domain
N900_17280	COG0494	nUDIX hydrolase
N900_17285	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
N900_17295	COG1309	transcriptional regulator
N900_17300	COG0513	Belongs to the DEAD box helicase family
N900_17305	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
N900_17315	COG0814	amino acid
N900_17320	COG0840	transmembrane signaling receptor activity
N900_17325	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N900_17330	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
N900_17340	COG1984	allophanate hydrolase subunit 2
N900_17355	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
N900_17360	COG4181	ATPase activity
N900_17370	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N900_17375	COG5001	Diguanylate cyclase
N900_17375	COG1716	ATPase activity
N900_17390	COG0484	heat shock protein binding
N900_17435	COG0546	phosphoglycolate phosphatase activity
N900_17450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N900_17455	COG1368	sulfuric ester hydrolase activity
N900_17465	COG0513	Belongs to the DEAD box helicase family
N900_17470	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
N900_17480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N900_17490	COG3046	protein related to deoxyribodipyrimidine photolyase
N900_17495	COG3397	chitin binding
N900_17500	COG3227	Zinc metalloprotease (Elastase)
N900_17510	COG0010	Belongs to the arginase family
N900_17515	COG1166	arginine decarboxylase activity
N900_17525	COG2239	Acts as a magnesium transporter
N900_17530	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
N900_17535	COG0459	protein refolding
N900_17545	COG0527	aspartate kinase activity
N900_17550	COG0662	Cupin 2, conserved barrel domain protein
N900_17555	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N900_17560	COG0456	acetyltransferase
N900_17565	COG2154	pterin-4-alpha-carbinolamine dehydratase
N900_17570	COG3186	Phenylalanine-4-hydroxylase
N900_17575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N900_17590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N900_17595	COG0583	DNA-binding transcription factor activity
N900_17610	COG2171	N-acyltransferase activity
N900_17615	COG1253	flavin adenine dinucleotide binding
N900_17620	COG1765	OsmC-like protein
N900_17645	COG0531	amino acid
N900_17650	COG3706	GGDEF domain
N900_17660	COG3279	Response regulator of the LytR AlgR family
N900_17665	COG3275	phosphorelay sensor kinase activity
N900_17680	COG0577	efflux transmembrane transporter activity
N900_17680	COG1136	(ABC) transporter
N900_17685	COG1136	(ABC) transporter
N900_17700	COG4989	oxidoreductase activity
N900_17705	COG0366	Alpha amylase catalytic
N900_17720	COG2067	long-chain fatty acid transport protein
N900_17725	COG2267	carboxylic ester hydrolase activity
N900_17735	COG3227	Zinc metalloprotease (Elastase)
N900_17740	COG3047	cAMP biosynthetic process
N900_17750	COG1686	Belongs to the peptidase S11 family
N900_17755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N900_17760	COG1271	oxidase subunit
N900_17765	COG1294	oxidase, subunit
N900_17775	COG3048	D-serine ammonia-lyase activity
N900_17780	COG0583	DNA-binding transcription factor activity
N900_17820	COG1063	alcohol dehydrogenase
N900_17835	COG0693	protein deglycase activity
N900_17850	COG0346	lactoylglutathione lyase activity
N900_17870	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N900_17875	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
N900_17880	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
N900_17885	COG0363	glucosamine-6-phosphate deaminase activity
N900_17890	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N900_17920	COG2610	gluconate transmembrane transporter activity
N900_17925	COG3835	regulator
N900_17935	COG0748	coenzyme F420 binding
N900_17940	COG3721	Heme iron utilization protein
N900_17950	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
N900_17955	COG0811	peptide transport
N900_17960	COG0848	biopolymer transport protein
N900_17965	COG4558	Periplasmic binding protein
N900_17970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N900_17975	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
N900_18010	COG3217	Mosc domain protein beta barrel domain protein
N900_18010	COG0633	Ferredoxin
N900_18010	COG0633	Ferredoxin
N900_18010	COG3217	Mosc domain protein beta barrel domain protein
N900_18015	COG0418	dihydroorotase activity
N900_18025	COG3152	Membrane
N900_18035	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N900_18040	COG2354	Protein conserved in bacteria
N900_18045	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
N900_18050	COG1278	Cold shock
N900_18075	COG3706	GGDEF domain
N900_18080	COG1349	DNA-binding transcription factor activity
N900_18095	COG3833	ABC-type maltose transport systems, permease component
N900_18100	COG1175	transmembrane transport
N900_18110	COG3842	ATPase activity
N900_18115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N900_18130	COG0393	Putative heavy-metal-binding
N900_18135	COG2197	response regulator
N900_18140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N900_18145	COG0835	chemotaxis
N900_18145	COG0784	Response regulator, receiver
N900_18150	COG1846	Transcriptional regulator
N900_18155	COG3706	GGDEF domain
N900_18190	COG0583	DNA-binding transcription factor activity
N900_18195	COG5001	Diguanylate cyclase
N900_18210	COG1741	Belongs to the pirin family
N900_18215	COG3123	guanosine phosphorylase activity
N900_18225	COG2211	Major facilitator Superfamily
N900_18235	COG0840	transmembrane signaling receptor activity
N900_18240	COG1067	ATP-dependent peptidase activity
N900_18250	COG4172	Belongs to the ABC transporter superfamily
N900_18270	COG0583	DNA-binding transcription factor activity
N900_18275	COG1620	l-lactate permease
N900_18280	COG1304	FMN binding
N900_18290	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
N900_18305	COG0840	transmembrane signaling receptor activity
N900_18315	COG0513	Belongs to the DEAD box helicase family
N900_18320	COG0583	DNA-binding transcription factor activity
N900_18330	COG1902	pentaerythritol trinitrate reductase activity
N900_18340	COG1132	(ABC) transporter
N900_18350	COG1902	pentaerythritol trinitrate reductase activity
N900_18360	COG1280	lysine exporter protein (LysE YggA)
N900_18365	COG2207	Transcriptional regulator
N900_18385	COG1846	Transcriptional regulator
N900_18390	COG1764	response to oxidative stress
N900_18395	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
N900_18400	COG0697	spore germination
N900_18410	COG0700	Nucleoside recognition
N900_18415	COG3366	ferrous iron transmembrane transporter activity
N900_18420	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
N900_18430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N900_18435	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
N900_18440	COG2259	Doxx family
N900_18465	COG0363	glucosamine-6-phosphate deaminase activity
N900_18480	COG4580	involved in the transport of maltose and maltodextrins
N900_18495	COG0840	transmembrane signaling receptor activity
N900_18510	COG0840	transmembrane signaling receptor activity
N900_18520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
N900_18525	COG1126	abc transporter atp-binding protein
N900_18535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N900_18540	COG4597	amino acid ABC transporter
N900_18545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N900_18560	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N900_18560	COG2213	PTS system mannitol-specific
N900_18565	COG0246	Mannitol dehydrogenase
N900_18570	COG3722	fumarate hydratase activity
N900_18575	COG0673	inositol 2-dehydrogenase activity
N900_18605	COG2910	NAD(P)H-binding
N900_18615	COG0840	transmembrane signaling receptor activity
N900_18620	COG4221	oxidoreductase activity
N900_18630	COG1901	pseudouridine methyltransferase
N900_18635	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N900_18645	COG0531	amino acid
N900_18650	COG1982	Orn Lys Arg decarboxylase major
N900_18675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N900_18700	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N900_18710	COG0259	pyridoxamine-phosphate oxidase activity
N900_18740	COG0745	RESPONSE REGULATOR receiver
N900_18760	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
N900_18765	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N900_18770	COG0840	transmembrane signaling receptor activity
N900_18775	COG0835	chemotaxis
N900_18780	COG0835	chemotaxis
N900_18815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N900_18825	COG2194	sulfuric ester hydrolase activity
N900_18830	COG0642	Histidine kinase
N900_18835	COG0745	RESPONSE REGULATOR receiver
N900_18865	COG1444	tRNA N-acetyltransferase activity
N900_18870	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine