locus-tag	class	description
VC0395_0001	COG2271	Major facilitator Superfamily
VC0395_0002	COG0584	glycerophosphoryl diester phosphodiesterase
VC0395_0004	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VC0395_0006	COG1609	Transcriptional regulator
VC0395_0007	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VC0395_0008	COG1879	ABC-type sugar transport system periplasmic component
VC0395_0009	COG1172	Belongs to the binding-protein-dependent transport system permease family
VC0395_0010	COG1129	ABC transporter
VC0395_0011	COG1869	D-ribose catabolic process
VC0395_0014	COG3501	Rhs element vgr protein
VC0395_0035	COG0564	pseudouridine synthase activity
VC0395_0037	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VC0395_0038	COG2771	luxR family
VC0395_0038	COG2200	EAL domain
VC0395_0040	COG0673	inositol 2-dehydrogenase activity
VC0395_0041	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VC0395_0048	COG1342	Belongs to the UPF0251 family
VC0395_0052	COG1301	dicarboxylic acid transport
VC0395_0057	COG2814	Major facilitator Superfamily
VC0395_0058	COG0583	DNA-binding transcription factor activity
VC0395_0059	COG5001	Diguanylate cyclase
VC0395_0059	COG3300	MHYT domain
VC0395_0060	COG0739	heme binding
VC0395_0062	COG0659	secondary active sulfate transmembrane transporter activity
VC0395_0066	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VC0395_0067	COG0581	inorganic phosphate transmembrane transporter activity
VC0395_0068	COG0573	inorganic phosphate transmembrane transporter activity
VC0395_0069	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VC0395_0075	COG1770	oligopeptidase
VC0395_0076	COG0513	Belongs to the DEAD box helicase family
VC0395_0079	COG1376	ErfK ybiS ycfS ynhG family protein
VC0395_0079	COG1388	LysM domain
VC0395_0080	COG0415	Belongs to the DNA photolyase family
VC0395_0082	COG3272	Protein of unknown function (DUF1722)
VC0395_0083	COG0813	purine-nucleoside phosphorylase activity
VC0395_0086	COG3706	GGDEF domain
VC0395_0088	COG1566	PFAM secretion protein HlyD family protein
VC0395_0092	COG0786	glutamate:sodium symporter activity
VC0395_0096	COG1999	signal sequence binding
VC0395_0098	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VC0395_0099	COG0671	phosphoesterase, PA-phosphatase related
VC0395_0107	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VC0395_0108	COG0471	metal ion transport
VC0395_0115	COG3501	Rhs element vgr protein
VC0395_0117	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VC0395_0118	COG1640	4-alpha-glucanotransferase
VC0395_0119	COG0058	SHG alpha-glucan phosphorylase activity
VC0395_0120	COG2909	trisaccharide binding
VC0395_0123	COG2084	Dehydrogenase
VC0395_0124	COG0217	transcriptional regulatory protein
VC0395_0132	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VC0395_0133	COG1444	tRNA N-acetyltransferase activity
VC0395_0139	COG0745	RESPONSE REGULATOR receiver
VC0395_0140	COG0642	Histidine kinase
VC0395_0141	COG2194	sulfuric ester hydrolase activity
VC0395_0143	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VC0395_0144	COG0601	transmembrane transport
VC0395_0148	COG2198	Histidine kinase
VC0395_0148	COG0643	Histidine kinase
VC0395_0149	COG0835	chemotaxis
VC0395_0150	COG0835	chemotaxis
VC0395_0151	COG0840	transmembrane signaling receptor activity
VC0395_0152	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VC0395_0153	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
VC0395_0157	COG0745	RESPONSE REGULATOR receiver
VC0395_0163	COG0259	pyridoxamine-phosphate oxidase activity
VC0395_0165	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VC0395_0171	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VC0395_0179	COG1982	Orn Lys Arg decarboxylase major
VC0395_0180	COG0531	amino acid
VC0395_0181	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VC0395_0182	COG1901	pseudouridine methyltransferase
VC0395_0184	COG4221	oxidoreductase activity
VC0395_0185	COG0840	transmembrane signaling receptor activity
VC0395_0187	COG2910	NAD(P)H-binding
VC0395_0193	COG0673	inositol 2-dehydrogenase activity
VC0395_0194	COG3722	fumarate hydratase activity
VC0395_0195	COG0246	Mannitol dehydrogenase
VC0395_0196	COG2213	PTS system mannitol-specific
VC0395_0196	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VC0395_0198	COG0739	heme binding
VC0395_0200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VC0395_0201	COG4597	amino acid ABC transporter
VC0395_0202	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VC0395_0204	COG1126	abc transporter atp-binding protein
VC0395_0205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VC0395_0207	COG0840	transmembrane signaling receptor activity
VC0395_0210	COG0840	transmembrane signaling receptor activity
VC0395_0213	COG4580	involved in the transport of maltose and maltodextrins
VC0395_0216	COG0363	glucosamine-6-phosphate deaminase activity
VC0395_0221	COG2259	Doxx family
VC0395_0222	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
VC0395_0223	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VC0395_0225	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
VC0395_0226	COG3366	ferrous iron transmembrane transporter activity
VC0395_0227	COG0700	Nucleoside recognition
VC0395_0229	COG0697	spore germination
VC0395_0230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VC0395_0231	COG1764	response to oxidative stress
VC0395_0232	COG1846	Transcriptional regulator
VC0395_0236	COG2207	Transcriptional regulator
VC0395_0237	COG1280	lysine exporter protein (LysE YggA)
VC0395_0240	COG1902	pentaerythritol trinitrate reductase activity
VC0395_0242	COG1132	(ABC) transporter
VC0395_0244	COG1902	pentaerythritol trinitrate reductase activity
VC0395_0246	COG0583	DNA-binding transcription factor activity
VC0395_0248	COG0513	Belongs to the DEAD box helicase family
VC0395_0250	COG0840	transmembrane signaling receptor activity
VC0395_0252	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
VC0395_0254	COG1304	FMN binding
VC0395_0255	COG1620	l-lactate permease
VC0395_0257	COG0583	DNA-binding transcription factor activity
VC0395_0261	COG4172	Belongs to the ABC transporter superfamily
VC0395_0263	COG1067	ATP-dependent peptidase activity
VC0395_0265	COG0840	transmembrane signaling receptor activity
VC0395_0267	COG2211	Major facilitator Superfamily
VC0395_0270	COG3123	guanosine phosphorylase activity
VC0395_0271	COG1741	Belongs to the pirin family
VC0395_0273	COG5001	Diguanylate cyclase
VC0395_0274	COG0583	DNA-binding transcription factor activity
VC0395_0283	COG3706	GGDEF domain
VC0395_0284	COG1846	Transcriptional regulator
VC0395_0285	COG0784	Response regulator, receiver
VC0395_0285	COG0835	chemotaxis
VC0395_0286	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VC0395_0287	COG2197	response regulator
VC0395_0288	COG0393	Putative heavy-metal-binding
VC0395_0291	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VC0395_0292	COG3842	ATPase activity
VC0395_0295	COG1175	transmembrane transport
VC0395_0296	COG3833	ABC-type maltose transport systems, permease component
VC0395_0299	COG1349	DNA-binding transcription factor activity
VC0395_0300	COG3706	GGDEF domain
VC0395_0303	COG4753	response regulator
VC0395_0303	COG2207	Transcriptional regulator
VC0395_0306	COG1278	Cold shock
VC0395_0307	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VC0395_0308	COG2354	Protein conserved in bacteria
VC0395_0309	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VC0395_0311	COG3152	Membrane
VC0395_0313	COG0418	dihydroorotase activity
VC0395_0315	COG0633	Ferredoxin
VC0395_0315	COG0633	Ferredoxin
VC0395_0315	COG3217	Mosc domain protein beta barrel domain protein
VC0395_0315	COG3217	Mosc domain protein beta barrel domain protein
VC0395_0322	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VC0395_0323	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VC0395_0324	COG4558	Periplasmic binding protein
VC0395_0325	COG0848	biopolymer transport protein
VC0395_0326	COG0811	peptide transport
VC0395_0327	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VC0395_0329	COG3721	Heme iron utilization protein
VC0395_0330	COG0748	coenzyme F420 binding
VC0395_0332	COG3835	regulator
VC0395_0333	COG2610	gluconate transmembrane transporter activity
VC0395_0334	COG1929	Belongs to the glycerate kinase type-1 family
VC0395_0339	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VC0395_0340	COG0363	glucosamine-6-phosphate deaminase activity
VC0395_0341	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VC0395_0342	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VC0395_0348	COG0346	lactoylglutathione lyase activity
VC0395_0351	COG0693	protein deglycase activity
VC0395_0353	COG1063	alcohol dehydrogenase
VC0395_0361	COG0583	DNA-binding transcription factor activity
VC0395_0362	COG3048	D-serine ammonia-lyase activity
VC0395_0364	COG1294	oxidase, subunit
VC0395_0365	COG1271	oxidase subunit
VC0395_0367	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VC0395_0368	COG1686	Belongs to the peptidase S11 family
VC0395_0370	COG3047	cAMP biosynthetic process
VC0395_0371	COG3227	Zinc metalloprotease (Elastase)
VC0395_0373	COG2267	carboxylic ester hydrolase activity
VC0395_0374	COG2067	long-chain fatty acid transport protein
VC0395_0377	COG0366	Alpha amylase catalytic
VC0395_0378	COG4989	oxidoreductase activity
VC0395_0382	COG1136	(ABC) transporter
VC0395_0383	COG1136	(ABC) transporter
VC0395_0383	COG0577	efflux transmembrane transporter activity
VC0395_0386	COG3275	phosphorelay sensor kinase activity
VC0395_0387	COG3279	Response regulator of the LytR AlgR family
VC0395_0389	COG3706	GGDEF domain
VC0395_0390	COG0531	amino acid
VC0395_0397	COG1765	OsmC-like protein
VC0395_0398	COG1253	flavin adenine dinucleotide binding
VC0395_0399	COG2171	N-acyltransferase activity
VC0395_0402	COG0583	DNA-binding transcription factor activity
VC0395_0403	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VC0395_0406	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VC0395_0407	COG3186	Phenylalanine-4-hydroxylase
VC0395_0408	COG2154	pterin-4-alpha-carbinolamine dehydratase
VC0395_0409	COG0456	acetyltransferase
VC0395_0410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VC0395_0411	COG0662	Cupin 2, conserved barrel domain protein
VC0395_0412	COG0527	aspartate kinase activity
VC0395_0414	COG0459	protein refolding
VC0395_0415	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VC0395_0416	COG2239	Acts as a magnesium transporter
VC0395_0419	COG1166	arginine decarboxylase activity
VC0395_0420	COG0010	Belongs to the arginase family
VC0395_0422	COG3227	Zinc metalloprotease (Elastase)
VC0395_0423	COG3397	chitin binding
VC0395_0425	COG3046	protein related to deoxyribodipyrimidine photolyase
VC0395_0427	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VC0395_0429	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
VC0395_0430	COG0513	Belongs to the DEAD box helicase family
VC0395_0432	COG1368	sulfuric ester hydrolase activity
VC0395_0433	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VC0395_0436	COG0546	phosphoglycolate phosphatase activity
VC0395_0445	COG1328	CTP reductase activity
VC0395_0446	COG0602	queuosine metabolic process
VC0395_0448	COG4067	protein conserved in archaea
VC0395_0448	COG0189	ligase activity
VC0395_0449	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VC0395_0449	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VC0395_0449	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VC0395_0450	COG1105	Belongs to the carbohydrate kinase PfkB family
VC0395_0451	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VC0395_0451	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VC0395_0452	COG1609	Transcriptional regulator
VC0395_0454	COG0419	ATPase involved in DNA repair
VC0395_0455	COG2205	protein histidine kinase activity
VC0395_0455	COG0784	Response regulator, receiver
VC0395_0456	COG0156	8-amino-7-oxononanoate synthase activity
VC0395_0459	COG0038	chloride channel
VC0395_0460	COG0523	cobalamin synthesis protein
VC0395_0462	COG3158	transport of potassium into the cell
VC0395_0463	COG0674	pyruvate-flavodoxin oxidoreductase activity
VC0395_0463	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
VC0395_0463	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VC0395_0463	COG1013	pyruvate-flavodoxin oxidoreductase activity
VC0395_0464	COG2205	protein histidine kinase activity
VC0395_0466	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VC0395_0467	COG0586	Pfam SNARE associated Golgi protein
VC0395_0470	COG2200	EAL domain
VC0395_0472	COG3038	cytochrome b561
VC0395_0473	COG2353	YceI-like domain
VC0395_0474	COG2116	formate transmembrane transporter activity
VC0395_0475	COG0583	DNA-binding transcription factor activity
VC0395_0477	COG3593	DNA synthesis involved in DNA repair
VC0395_0478	COG0737	Belongs to the 5'-nucleotidase family
VC0395_0479	COG0861	Integral membrane protein TerC family
VC0395_0481	COG2824	Alkylphosphonate utilization operon protein PhnA
VC0395_0493	COG3706	GGDEF domain
VC0395_0497	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VC0395_0498	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VC0395_0500	COG0745	RESPONSE REGULATOR receiver
VC0395_0511	COG4128	Pfam Zonular occludens toxin
VC0395_0513	COG0023	Translation Initiation Factor
VC0395_0515	COG1181	Belongs to the D-alanine--D-alanine ligase family
VC0395_0517	COG0045	succinate-CoA ligase (ADP-forming) activity
VC0395_0517	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VC0395_0517	COG1042	CoA-binding domain protein
VC0395_0518	COG0583	DNA-binding transcription factor activity
VC0395_0519	COG4771	TonB-dependent receptor
VC0395_0519	COG1629	transport
VC0395_0523	COG2050	protein possibly involved in aromatic compounds catabolism
VC0395_0528	COG0625	glutathione transferase activity
VC0395_0531	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VC0395_0532	COG4172	Belongs to the ABC transporter superfamily
VC0395_0533	COG4239	(ABC) transporter, permease
VC0395_0534	COG4174	ABC transporter (Permease)
VC0395_0535	COG4166	transmembrane transport
VC0395_0544	COG3842	ATPase activity
VC0395_0546	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VC0395_0548	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VC0395_0549	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VC0395_0550	COG1011	Hydrolase
VC0395_0552	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VC0395_0554	COG1970	mechanosensitive ion channel activity
VC0395_0556	COG2759	Belongs to the formate--tetrahydrofolate ligase family
VC0395_0557	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VC0395_0557	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VC0395_0558	COG0302	gtp cyclohydrolase
VC0395_0560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VC0395_0562	COG2897	thiosulfate sulfurtransferase activity
VC0395_0563	COG2390	Transcriptional regulator
VC0395_0564	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
VC0395_0565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VC0395_0569	COG3039	Transposase
VC0395_0573	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VC0395_0579	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
VC0395_0580	COG0583	DNA-binding transcription factor activity
VC0395_0581	COG0778	Nitroreductase
VC0395_0586	COG0640	Transcriptional regulator
VC0395_0588	COG0446	pyridine nucleotide-disulphide oxidoreductase
VC0395_0597	COG1263	PTS System
VC0395_0597	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VC0395_0599	COG1621	beta-fructofuranosidase activity
VC0395_0600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VC0395_0601	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VC0395_0603	COG2885	chlorophyll binding
VC0395_0604	COG0545	Peptidyl-prolyl cis-trans isomerase
VC0395_0605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VC0395_0606	COG0840	transmembrane signaling receptor activity
VC0395_0607	COG3069	C4-dicarboxylate transmembrane transporter activity
VC0395_0608	COG1760	l-serine dehydratase
VC0395_0612	COG1609	Transcriptional regulator
VC0395_0613	COG2197	response regulator
VC0395_0614	COG3850	Histidine kinase
VC0395_0615	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VC0395_0617	COG0243	molybdopterin cofactor binding
VC0395_0621	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VC0395_0622	COG2197	response regulator
VC0395_0623	COG3851	Histidine kinase
VC0395_0624	COG2271	Major facilitator Superfamily
VC0395_0625	COG1840	ABC-type Fe3 transport system, periplasmic component
VC0395_0627	COG3842	ATPase activity
VC0395_0628	COG3243	poly(R)-hydroxyalkanoic acid synthase
VC0395_0630	COG0183	Belongs to the thiolase family
VC0395_0632	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VC0395_0633	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VC0395_0636	COG3706	GGDEF domain
VC0395_0637	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VC0395_0640	COG1979	alcohol dehydrogenase
VC0395_0643	COG4191	Histidine kinase
VC0395_0644	COG1840	ABC-type Fe3 transport system, periplasmic component
VC0395_0646	COG2271	Major facilitator Superfamily
VC0395_0647	COG0469	pyruvate kinase activity
VC0395_0648	COG0784	Response regulator, receiver
VC0395_0648	COG2198	Histidine kinase
VC0395_0648	COG2205	protein histidine kinase activity
VC0395_0649	COG1879	ABC-type sugar transport system periplasmic component
VC0395_0650	COG1803	Methylglyoxal synthase
VC0395_0651	COG1335	isochorismatase
VC0395_0653	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VC0395_0656	COG0210	DNA helicase
VC0395_0657	COG1289	transmembrane transporter activity
VC0395_0663	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
VC0395_0664	COG4149	molybdate abc transporter
VC0395_0665	COG0725	ABC transporter, periplasmic molybdate-binding protein
VC0395_0666	COG1492	cobalamin metabolic process
VC0395_0671	COG5002	protein histidine kinase activity
VC0395_0671	COG0784	Response regulator, receiver
VC0395_0673	COG1879	ABC-type sugar transport system periplasmic component
VC0395_0675	COG2827	Endonuclease containing a URI domain
VC0395_0676	COG3132	Protein of unknown function, DUF480
VC0395_0682	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
VC0395_0683	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VC0395_0686	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VC0395_0687	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
VC0395_0688	COG0247	lactate metabolic process
VC0395_0689	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VC0395_0690	COG3118	belongs to the thioredoxin family
VC0395_0697	COG0583	DNA-binding transcription factor activity
VC0395_0698	COG4160	amino acid transport
VC0395_0699	COG4215	(ABC) transporter
VC0395_0700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VC0395_0701	COG1126	abc transporter atp-binding protein
VC0395_0703	COG2425	protein containing a von Willebrand factor type A (vWA) domain
VC0395_0705	COG0494	nUDIX hydrolase
VC0395_0706	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VC0395_0708	COG1309	transcriptional regulator
VC0395_0709	COG0513	Belongs to the DEAD box helicase family
VC0395_0710	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
VC0395_0712	COG0814	amino acid
VC0395_0713	COG0840	transmembrane signaling receptor activity
VC0395_0714	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VC0395_0716	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
VC0395_0718	COG1984	allophanate hydrolase subunit 2
VC0395_0722	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VC0395_0723	COG4181	ATPase activity
VC0395_0725	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VC0395_0726	COG5001	Diguanylate cyclase
VC0395_0726	COG1716	ATPase activity
VC0395_0728	COG0484	heat shock protein binding
VC0395_0740	COG0346	lactoylglutathione lyase activity
VC0395_0751	COG1943	Transposase
VC0395_0796	COG0346	lactoylglutathione lyase activity
VC0395_0799	COG0110	maltose O-acetyltransferase activity
VC0395_0800	COG3039	Transposase
VC0395_0803	COG2944	sequence-specific DNA binding
VC0395_0804	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
VC0395_0813	COG4977	sequence-specific DNA binding
VC0395_0814	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
VC0395_0824	COG3040	lipid binding
VC0395_0829	COG1619	proteins homologs of microcin C7 resistance protein MccF
VC0395_0837	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
VC0395_0868	COG3040	lipid binding
VC0395_0878	COG3040	lipid binding
VC0395_0886	COG1619	proteins homologs of microcin C7 resistance protein MccF
VC0395_0905	COG1280	lysine exporter protein (LysE YggA)
VC0395_0906	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
VC0395_0912	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
VC0395_0920	COG0346	lactoylglutathione lyase activity
VC0395_0927	COG0384	phenazine biosynthesis protein PhzF
VC0395_0929	COG3093	addiction module antidote protein HigA
VC0395_0930	COG3549	Plasmid maintenance system killer
VC0395_0933	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
VC0395_0939	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
VC0395_0940	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VC0395_0942	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
VC0395_0947	COG3039	Transposase
VC0395_0949	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VC0395_0952	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VC0395_0953	COG0509	glycine decarboxylation via glycine cleavage system
VC0395_0955	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VC0395_0955	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VC0395_0956	COG1943	Transposase
VC0395_0960	COG1686	Belongs to the peptidase S11 family
VC0395_0963	COG2814	Major facilitator Superfamily
VC0395_0966	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VC0395_0972	COG5002	protein histidine kinase activity
VC0395_0973	COG0745	RESPONSE REGULATOR receiver
VC0395_0979	COG0366	Alpha amylase catalytic
VC0395_0980	COG3038	cytochrome b561
VC0395_0986	COG0561	phosphatase activity
VC0395_0987	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
VC0395_0988	COG3623	hexulose-6-phosphate isomerase
VC0395_0990	COG0745	RESPONSE REGULATOR receiver
VC0395_0994	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VC0395_0998	COG4604	ABC transporter, ATP-binding protein
VC0395_0999	COG4605	iron ion homeostasis
VC0395_1000	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VC0395_1004	COG3291	Pkd domain containing protein
VC0395_1004	COG4412	M6 family metalloprotease domain protein
VC0395_1005	COG5380	lipid catabolic process
VC0395_1006	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VC0395_1007	COG0840	transmembrane signaling receptor activity
VC0395_1011	COG3240	lipase activity
VC0395_1013	COG3706	GGDEF domain
VC0395_1015	COG2814	Major facilitator Superfamily
VC0395_1016	COG1757	Na H antiporter
VC0395_1018	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VC0395_1018	COG4191	Histidine kinase
VC0395_1019	COG3437	response regulator, receiver
VC0395_1019	COG0784	Response regulator, receiver
VC0395_1020	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VC0395_1021	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VC0395_1023	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VC0395_1024	COG0513	Belongs to the DEAD box helicase family
VC0395_1025	COG1943	Transposase
VC0395_1030	COG0516	GMP reductase activity
VC0395_1059	COG4695	Portal protein
VC0395_1079	COG4974	Belongs to the 'phage' integrase family
VC0395_1080	COG0516	GMP reductase activity
VC0395_1082	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VC0395_1084	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VC0395_1084	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VC0395_1085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VC0395_1091	COG3036	rescue of stalled ribosome
VC0395_1092	COG1278	Cold shock
VC0395_1093	COG1017	nitric oxide dioxygenase activity
VC0395_1093	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VC0395_1095	COG3604	Transcriptional regulator
VC0395_1096	COG2195	Cleaves the N-terminal amino acid of tripeptides
VC0395_1098	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VC0395_1102	COG0840	transmembrane signaling receptor activity
VC0395_1103	COG0714	Associated with various cellular activities
VC0395_1107	COG2304	oxidoreductase activity
VC0395_1111	COG1278	Cold shock
VC0395_1112	COG5001	Diguanylate cyclase
VC0395_1112	COG5002	protein histidine kinase activity
VC0395_1114	COG3530	Putative quorum-sensing-regulated virulence factor
VC0395_1117	COG3033	Beta-eliminating lyase
VC0395_1118	COG0814	amino acid
VC0395_1119	COG0589	response to stress
VC0395_1121	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VC0395_1121	COG2111	Na H antiporter
VC0395_1125	COG2212	antiporter activity
VC0395_1126	COG1320	monovalent cation:proton antiporter activity
VC0395_1127	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VC0395_1127	COG1017	nitric oxide dioxygenase activity
VC0395_1128	COG0242	peptide deformylase activity
VC0395_1130	COG0579	oxidoreductase
VC0395_A0002	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VC0395_A0003	COG1194	a g-specific adenine glycosylase
VC0395_A0005	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VC0395_A0006	COG2066	Belongs to the glutaminase family
VC0395_A0007	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VC0395_A0008	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VC0395_A0010	COG1872	DUF167
VC0395_A0011	COG0762	integral membrane protein
VC0395_A0012	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VC0395_A0013	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VC0395_A0017	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VC0395_A0018	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VC0395_A0019	COG1678	Uncharacterized ACR, COG1678
VC0395_A0020	COG0189	ligase activity
VC0395_A0021	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VC0395_A0022	COG2356	endonuclease I
VC0395_A0023	COG3091	SprT-like family
VC0395_A0024	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VC0395_A0026	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VC0395_A0027	COG0583	DNA-binding transcription factor activity
VC0395_A0028	COG4771	TonB-dependent receptor
VC0395_A0029	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VC0395_A0030	COG0126	phosphoglycerate kinase activity
VC0395_A0031	COG0191	fructose-bisphosphate aldolase activity
VC0395_A0032	COG0668	transmembrane transport
VC0395_A0033	COG1279	arginine transmembrane transporter activity
VC0395_A0034	COG0583	DNA-binding transcription factor activity
VC0395_A0037	COG0469	pyruvate kinase activity
VC0395_A0038	COG1349	DNA-binding transcription factor activity
VC0395_A0039	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VC0395_A0040	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VC0395_A0044	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VC0395_A0045	COG0358	DNA primase activity
VC0395_A0046	COG1610	YqeY-like protein
VC0395_A0047	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VC0395_A0049	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VC0395_A0051	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VC0395_A0052	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VC0395_A0053	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VC0395_A0054	COG1968	undecaprenyl-diphosphatase activity
VC0395_A0055	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VC0395_A0056	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VC0395_A0057	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VC0395_A0058	COG0585	pseudouridine synthase activity
VC0395_A0059	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VC0395_A0060	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VC0395_A0061	COG1388	LysM domain
VC0395_A0061	COG4942	peptidase
VC0395_A0062	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VC0395_A0063	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VC0395_A0067	COG4208	sulfate ABC transporter
VC0395_A0068	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
VC0395_A0070	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VC0395_A0071	COG2137	regulation of response to DNA damage stimulus
VC0395_A0072	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VC0395_A0074	COG0527	aspartate kinase activity
VC0395_A0075	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
VC0395_A0084	COG3630	sodium ion export across plasma membrane
VC0395_A0085	COG5016	pyruvate
VC0395_A0085	COG0511	ligase activity, forming carbon-carbon bonds
VC0395_A0086	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VC0395_A0088	COG1238	metal cluster binding
VC0395_A0089	COG0612	Peptidase, M16
VC0395_A0090	COG2918	glutathione biosynthetic process
VC0395_A0091	COG1854	S-ribosylhomocysteine lyase activity
VC0395_A0092	COG4536	flavin adenine dinucleotide binding
VC0395_A0093	COG4137	Cytochrome C assembly protein
VC0395_A0094	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VC0395_A0095	COG0228	four-way junction DNA binding
VC0395_A0096	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VC0395_A0097	COG0336	Belongs to the RNA methyltransferase TrmD family
VC0395_A0098	COG0335	large ribosomal subunit rRNA binding
VC0395_A0099	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VC0395_A0100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VC0395_A0102	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VC0395_A0103	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VC0395_A0104	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VC0395_A0105	COG0723	plastoquinol--plastocyanin reductase activity
VC0395_A0106	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VC0395_A0107	COG2857	Cytochrome c1
VC0395_A0108	COG0625	glutathione transferase activity
VC0395_A0109	COG2969	positive regulation of protein catabolic process
VC0395_A0110	COG2823	Periplasmic or secreted lipoprotein
VC0395_A0111	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VC0395_A0112	COG0792	nuclease activity
VC0395_A0113	COG3107	peptidoglycan biosynthetic process
VC0395_A0114	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VC0395_A0118	COG0288	reversible hydration of carbon dioxide
VC0395_A0119	COG0659	secondary active sulfate transmembrane transporter activity
VC0395_A0120	COG1131	(ABC) transporter
VC0395_A0121	COG0842	Transport permease protein
VC0395_A0122	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VC0395_A0123	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VC0395_A0124	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VC0395_A0126	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VC0395_A0127	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VC0395_A0128	COG1489	DNA binding
VC0395_A0130	COG1643	Atp-dependent helicase
VC0395_A0131	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VC0395_A0132	COG1752	Esterase of the alpha-beta hydrolase superfamily
VC0395_A0133	COG1049	propionate catabolic process, 2-methylcitrate cycle
VC0395_A0134	COG3112	Uncharacterised protein family (UPF0231)
VC0395_A0135	COG0347	Belongs to the P(II) protein family
VC0395_A0136	COG0004	ammonium transporteR
VC0395_A0137	COG1840	ABC-type Fe3 transport system, periplasmic component
VC0395_A0139	COG3842	ATPase activity
VC0395_A0140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VC0395_A0143	COG2971	BadF BadG BcrA BcrD
VC0395_A0145	COG4608	Belongs to the ABC transporter superfamily
VC0395_A0146	COG0444	Belongs to the ABC transporter superfamily
VC0395_A0147	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VC0395_A0148	COG0601	transmembrane transport
VC0395_A0149	COG0747	negative chemotaxis
VC0395_A0151	COG2813	Specifically methylates the guanine in position
VC0395_A0152	COG0628	permease
VC0395_A0154	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VC0395_A0156	COG0316	Belongs to the HesB IscA family
VC0395_A0159	COG0739	heme binding
VC0395_A0160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VC0395_A0161	COG2027	D-alanyl-D-alanine carboxypeptidase
VC0395_A0162	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VC0395_A0163	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VC0395_A0164	COG1534	Rna-binding protein
VC0395_A0165	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VC0395_A0166	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VC0395_A0167	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VC0395_A0168	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VC0395_A0169	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VC0395_A0172	COG0779	Required for maturation of 30S ribosomal subunits
VC0395_A0173	COG0195	Participates in both transcription termination and antitermination
VC0395_A0174	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VC0395_A0175	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VC0395_A0176	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
VC0395_A0177	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VC0395_A0178	COG1185	polyribonucleotide nucleotidyltransferase activity
VC0395_A0179	COG4785	May be involved in cell division
VC0395_A0186	COG3153	acetyltransferase
VC0395_A0190	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
VC0395_A0191	COG0513	Belongs to the DEAD box helicase family
VC0395_A0192	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
VC0395_A0194	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VC0395_A0195	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VC0395_A0196	COG2204	response regulator
VC0395_A0199	COG0667	Aldo Keto reductase
VC0395_A0200	COG3066	DNA modification
VC0395_A0203	COG0494	nUDIX hydrolase
VC0395_A0204	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
VC0395_A0205	COG0730	response to heat
VC0395_A0206	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VC0395_A0207	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
VC0395_A0208	COG1283	sodium-dependent phosphate transmembrane transporter activity
VC0395_A0209	COG0583	DNA-binding transcription factor activity
VC0395_A0210	COG0640	Transcriptional regulator
VC0395_A0211	COG0268	Binds directly to 16S ribosomal RNA
VC0395_A0212	COG0728	peptidoglycan biosynthetic process
VC0395_A0213	COG0196	riboflavin kinase activity
VC0395_A0214	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
VC0395_A0215	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VC0395_A0216	COG1047	Peptidyl-prolyl cis-trans
VC0395_A0217	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VC0395_A0218	COG1966	Carbon starvation protein
VC0395_A0221	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VC0395_A0222	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VC0395_A0223	COG1472	Belongs to the glycosyl hydrolase 3 family
VC0395_A0224	COG3279	Response regulator of the LytR AlgR family
VC0395_A0225	COG3275	phosphorelay sensor kinase activity
VC0395_A0226	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VC0395_A0227	COG0287	Prephenate dehydrogenase
VC0395_A0227	COG1605	Chorismate mutase
VC0395_A0229	COG0488	(ABC) transporter
VC0395_A0231	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VC0395_A0232	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
VC0395_A0233	COG5001	Diguanylate cyclase
VC0395_A0234	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VC0395_A0235	COG1605	Chorismate mutase
VC0395_A0235	COG0077	Prephenate dehydratase
VC0395_A0236	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VC0395_A0237	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VC0395_A0238	COG0564	pseudouridine synthase activity
VC0395_A0240	COG0542	response to heat
VC0395_A0250	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VC0395_A0252	COG2974	May be involved in recombination
VC0395_A0253	COG0745	RESPONSE REGULATOR receiver
VC0395_A0254	COG5002	protein histidine kinase activity
VC0395_A0256	COG0248	Ppx GppA phosphatase
VC0395_A0257	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VC0395_A0259	COG0581	inorganic phosphate transmembrane transporter activity
VC0395_A0260	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VC0395_A0263	COG3142	Participates in the control of copper homeostasis
VC0395_A0264	COG0450	alkyl hydroperoxide reductase
VC0395_A0265	COG0583	DNA-binding transcription factor activity
VC0395_A0266	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VC0395_A0268	COG0517	IMP dehydrogenase activity
VC0395_A0269	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
VC0395_A0270	COG0343	queuine tRNA-ribosyltransferase activity
VC0395_A0271	COG1862	Preprotein translocase
VC0395_A0272	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VC0395_A0273	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VC0395_A0274	COG0483	inositol monophosphate 1-phosphatase activity
VC0395_A0276	COG1959	2 iron, 2 sulfur cluster binding
VC0395_A0277	COG1104	cysteine desulfurase activity
VC0395_A0278	COG0822	iron-sulfur transferase activity
VC0395_A0280	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VC0395_A0281	COG0443	Heat shock 70 kDa protein
VC0395_A0282	COG0633	Ferredoxin
VC0395_A0283	COG2975	iron-sulfur cluster assembly
VC0395_A0284	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VC0395_A0285	COG0105	UTP biosynthetic process
VC0395_A0286	COG0820	rRNA (adenine-C2-)-methyltransferase activity
VC0395_A0288	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VC0395_A0289	COG0124	histidyl-tRNA synthetase
VC0395_A0290	COG2976	Protein conserved in bacteria
VC0395_A0291	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VC0395_A0292	COG1160	GTP binding
VC0395_A0294	COG1570	exodeoxyribonuclease VII activity
VC0395_A0296	COG0517	IMP dehydrogenase activity
VC0395_A0296	COG0516	GMP reductase activity
VC0395_A0297	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VC0395_A0297	COG0519	Catalyzes the synthesis of GMP from XMP
VC0395_A0299	COG1584	GPR1 FUN34 yaaH family protein
VC0395_A0300	COG3433	isochorismatase activity
VC0395_A0300	COG1535	isochorismatase
VC0395_A0301	COG1021	2,3-dihydroxybenzoate-AMP ligase
VC0395_A0302	COG1169	isochorismate synthase
VC0395_A0303	COG1028	Short-chain dehydrogenase reductase Sdr
VC0395_A0305	COG4592	Periplasmic binding protein
VC0395_A0306	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VC0395_A0307	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VC0395_A0308	COG1120	ATPase activity
VC0395_A0310	COG0583	DNA-binding transcription factor activity
VC0395_A0311	COG2015	COG2015, Alkyl sulfatase and related hydrolases
VC0395_A0312	COG1115	amino acid carrier protein
VC0395_A0313	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VC0395_A0314	COG0583	DNA-binding transcription factor activity
VC0395_A0317	COG4565	transcriptional regulatory protein
VC0395_A0319	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VC0395_A0320	COG5016	pyruvate
VC0395_A0320	COG0511	ligase activity, forming carbon-carbon bonds
VC0395_A0321	COG3630	sodium ion export across plasma membrane
VC0395_A0323	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
VC0395_A0324	COG3052	prosthetic group binding
VC0395_A0325	COG2301	Belongs to the HpcH HpaI aldolase family
VC0395_A0326	COG3051	citrate lyase alpha subunit
VC0395_A0327	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
VC0395_A0328	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
VC0395_A0330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VC0395_A0331	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VC0395_A0332	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VC0395_A0344	COG1012	belongs to the aldehyde dehydrogenase family
VC0395_A0349	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
VC0395_A0350	COG0840	transmembrane signaling receptor activity
VC0395_A0351	COG3710	Transcriptional regulator
VC0395_A0356	COG4796	Type ii and iii secretion system protein
VC0395_A0360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VC0395_A0361	COG1459	type II secretion system
VC0395_A0363	COG2207	Transcriptional regulator
VC0395_A0364	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
VC0395_A0367	COG0739	heme binding
VC0395_A0369	COG3064	Membrane
VC0395_A0370	COG3064	Membrane
VC0395_A0372	COG0582	viral genome integration into host DNA
VC0395_A0374	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VC0395_A0375	COG2867	negative regulation of translational initiation
VC0395_A0376	COG2914	Belongs to the UPF0125 (RnfH) family
VC0395_A0377	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VC0395_A0378	COG0497	DNA recombination
VC0395_A0379	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VC0395_A0381	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VC0395_A0382	COG0443	Heat shock 70 kDa protein
VC0395_A0383	COG0484	heat shock protein binding
VC0395_A0385	COG4968	Prepilin-type N-terminal cleavage methylation domain
VC0395_A0389	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VC0395_A0390	COG0590	tRNA wobble adenosine to inosine editing
VC0395_A0392	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VC0395_A0395	COG0047	phosphoribosylformylglycinamidine synthase activity
VC0395_A0395	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VC0395_A0396	COG1943	Transposase
VC0395_A0400	COG0442	prolyl-tRNA aminoacylation
VC0395_A0401	COG1720	tRNA m6t6A37 methyltransferase activity
VC0395_A0402	COG0254	rRNA binding
VC0395_A0403	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VC0395_A0404	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VC0395_A0405	COG1671	Belongs to the UPF0178 family
VC0395_A0408	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VC0395_A0410	COG3098	single-species biofilm formation
VC0395_A0411	COG0564	pseudouridine synthase activity
VC0395_A0412	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VC0395_A0413	COG0142	geranyltranstransferase activity
VC0395_A0414	COG1722	exodeoxyribonuclease VII activity
VC0395_A0415	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VC0395_A0417	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VC0395_A0417	COG0301	tRNA thio-modification
VC0395_A0418	COG0583	DNA-binding transcription factor activity
VC0395_A0419	COG2363	Small membrane protein
VC0395_A0420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VC0395_A0421	COG1611	Belongs to the LOG family
VC0395_A0422	COG3706	GGDEF domain
VC0395_A0424	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VC0395_A0424	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VC0395_A0426	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VC0395_A0427	COG1464	Belongs to the NlpA lipoprotein family
VC0395_A0428	COG2011	ABC-type metal ion transport system permease component
VC0395_A0429	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VC0395_A0430	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VC0395_A0431	COG1609	Transcriptional regulator
VC0395_A0432	COG1263	PTS System
VC0395_A0432	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VC0395_A0433	COG0366	Alpha amylase catalytic
VC0395_A0439	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VC0395_A0440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VC0395_A0441	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VC0395_A0442	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VC0395_A0443	COG0110	maltose O-acetyltransferase activity
VC0395_A0448	COG1045	serine acetyltransferase
VC0395_A0450	COG0438	transferase activity, transferring glycosyl groups
VC0395_A0452	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
VC0395_A0458	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VC0395_A0460	COG1596	polysaccharide export
VC0395_A0465	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VC0395_A0467	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VC0395_A0468	COG0321	lipoyl(octanoyl) transferase activity
VC0395_A0469	COG2921	Belongs to the UPF0250 family
VC0395_A0470	COG1686	Belongs to the peptidase S11 family
VC0395_A0471	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VC0395_A0472	COG0772	Belongs to the SEDS family
VC0395_A0473	COG0768	penicillin binding
VC0395_A0474	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VC0395_A0475	COG0799	negative regulation of ribosome biogenesis
VC0395_A0476	COG1466	dna polymerase III delta subunit
VC0395_A0477	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VC0395_A0478	COG0495	leucyl-tRNA aminoacylation
VC0395_A0479	COG2888	peptidyl-tyrosine sulfation
VC0395_A0480	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VC0395_A0481	COG4535	Mg2 and Co2 transporter CorC
VC0395_A0482	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VC0395_A0483	COG1702	phosphate starvation-inducible protein PhoH
VC0395_A0484	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VC0395_A0485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VC0395_A0486	COG2190	(PTS) system
VC0395_A0488	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VC0395_A0489	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VC0395_A0490	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VC0395_A0491	COG3115	cell septum assembly
VC0395_A0492	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VC0395_A0495	COG0789	Transcriptional regulator
VC0395_A0496	COG1585	Membrane protein implicated in regulation of membrane protease activity
VC0395_A0497	COG0330	HflC and HflK could
VC0395_A0498	COG3118	belongs to the thioredoxin family
VC0395_A0500	COG0300	oxidoreductase activity
VC0395_A0501	COG1090	epimerase
VC0395_A0502	COG0622	Phosphoesterase
VC0395_A0505	COG3710	Transcriptional regulator
VC0395_A0506	COG0326	Molecular chaperone. Has ATPase activity
VC0395_A0507	COG0563	adenylate kinase activity
VC0395_A0508	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VC0395_A0512	COG0367	asparagine synthase
VC0395_A0513	COG4651	solute:proton antiporter activity
VC0395_A0513	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VC0395_A0514	COG1940	carbohydrate kinase activity
VC0395_A0514	COG1846	Transcriptional regulator
VC0395_A0515	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VC0395_A0516	COG2190	(PTS) system
VC0395_A0516	COG1263	PTS System
VC0395_A0516	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VC0395_A0517	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VC0395_A0520	COG0101	tRNA pseudouridine synthase activity
VC0395_A0521	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VC0395_A0522	COG0285	dihydrofolate synthase activity
VC0395_A0523	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VC0395_A0524	COG1286	toxin biosynthetic process
VC0395_A0525	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VC0395_A0526	COG2056	Na+-H+ antiporter family
VC0395_A0527	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VC0395_A0531	COG0346	lactoylglutathione lyase activity
VC0395_A0532	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VC0395_A0533	COG4660	Part of a membrane complex involved in electron transport
VC0395_A0534	COG4659	FMN binding
VC0395_A0535	COG4658	electron transport chain
VC0395_A0536	COG4656	Part of a membrane complex involved in electron transport
VC0395_A0537	COG2878	Part of a membrane complex involved in electron transport
VC0395_A0538	COG4657	Part of a membrane complex involved in electron transport
VC0395_A0540	COG0556	nucleotide-excision repair
VC0395_A0541	COG2204	response regulator
VC0395_A0542	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VC0395_A0543	COG2198	Histidine kinase
VC0395_A0544	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VC0395_A0545	COG0521	Mo-molybdopterin cofactor biosynthetic process
VC0395_A0546	COG0315	cyclic pyranopterin monophosphate synthase activity
VC0395_A0547	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VC0395_A0548	COG0314	molybdopterin synthase activity
VC0395_A0549	COG2199	diguanylate cyclase activity
VC0395_A0550	COG4109	DRTGG domain
VC0395_A0552	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VC0395_A0554	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VC0395_A0554	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VC0395_A0555	COG0489	protein tyrosine kinase activity
VC0395_A0556	COG0572	uridine kinase
VC0395_A0557	COG2982	Protein involved in outer membrane biogenesis
VC0395_A0558	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VC0395_A0559	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VC0395_A0561	COG2067	long-chain fatty acid transport protein
VC0395_A0564	COG0183	Belongs to the thiolase family
VC0395_A0565	COG1250	3-hydroxyacyl-CoA dehydrogenase
VC0395_A0565	COG1024	Enoyl-CoA hydratase
VC0395_A0566	COG0778	Nitroreductase
VC0395_A0567	COG0583	DNA-binding transcription factor activity
VC0395_A0568	COG0745	RESPONSE REGULATOR receiver
VC0395_A0570	COG2832	Protein of unknown function (DUF454)
VC0395_A0571	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VC0395_A0572	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
VC0395_A0573	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VC0395_A0574	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VC0395_A0577	COG1028	Short-chain dehydrogenase reductase Sdr
VC0395_A0578	COG0616	signal peptide processing
VC0395_A0580	COG1522	sequence-specific DNA binding
VC0395_A0581	COG1946	Acyl-CoA thioesterase
VC0395_A0585	COG3706	GGDEF domain
VC0395_A0586	COG0640	Transcriptional regulator
VC0395_A0587	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VC0395_A0594	COG1881	PFAM PEBP family protein
VC0395_A0598	COG0009	L-threonylcarbamoyladenylate synthase
VC0395_A0601	COG2201	protein-glutamate methylesterase activity
VC0395_A0603	COG5002	protein histidine kinase activity
VC0395_A0604	COG4191	Histidine kinase
VC0395_A0605	COG5001	Diguanylate cyclase
VC0395_A0605	COG3300	MHYT domain
VC0395_A0606	COG2204	response regulator
VC0395_A0610	COG0601	transmembrane transport
VC0395_A0611	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VC0395_A0612	COG0444	Belongs to the ABC transporter superfamily
VC0395_A0613	COG4608	Belongs to the ABC transporter superfamily
VC0395_A0614	COG0435	Glutathione S-transferase
VC0395_A0615	COG0280	phosphate acetyltransferase
VC0395_A0615	COG0857	belongs to the CobB CobQ family
VC0395_A0616	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VC0395_A0617	COG3092	negative regulation of chromosome organization
VC0395_A0618	COG4628	conserved protein (DUF2132)
VC0395_A0620	COG4120	Belongs to the binding-protein-dependent transport system permease family
VC0395_A0622	COG2203	Gaf domain
VC0395_A0622	COG2199	diguanylate cyclase activity
VC0395_A0623	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VC0395_A0624	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VC0395_A0625	COG0653	protein targeting
VC0395_A0626	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VC0395_A0627	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VC0395_A0628	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VC0395_A0629	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VC0395_A0630	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VC0395_A0631	COG0156	8-amino-7-oxononanoate synthase activity
VC0395_A0632	COG2226	methyltransferase
VC0395_A0633	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VC0395_A0635	COG0501	Belongs to the peptidase M48B family
VC0395_A0637	COG0300	oxidoreductase activity
VC0395_A0640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VC0395_A0642	COG2268	Band 7 protein
VC0395_A0644	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VC0395_A0645	COG2915	High frequency lysogenization protein hflD homolog
VC0395_A0646	COG0482	sulfurtransferase activity
VC0395_A0647	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VC0395_A0649	COG3423	Transcriptional regulator
VC0395_A0650	COG2801	Transposase and inactivated derivatives
VC0395_A0651	COG2842	Transposition protein
VC0395_A0671	COG0640	Transcriptional regulator
VC0395_A0673	COG4373	Mu-like prophage FluMu protein gp28
VC0395_A0674	COG4383	Mu-like prophage protein gp29
VC0395_A0682	COG4397	Mu-like prophage major head subunit gpT
VC0395_A0684	COG4387	Mu-like prophage protein GP36
VC0395_A0688	COG4386	tail sheath protein
VC0395_A0690	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
VC0395_A0694	COG4384	Bacteriophage Mu Gp45 protein
VC0395_A0696	COG3299	homolog of phage Mu protein gp47
VC0395_A0697	COG3778	Protein conserved in bacteria
VC0395_A0700	COG2916	Histone family protein nucleoid-structuring protein H-NS
VC0395_A0701	COG1757	Na H antiporter
VC0395_A0702	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VC0395_A0703	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VC0395_A0704	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VC0395_A0705	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VC0395_A0705	COG0131	Imidazoleglycerol-phosphate dehydratase
VC0395_A0706	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VC0395_A0707	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VC0395_A0708	COG0107	imidazoleglycerol-phosphate synthase activity
VC0395_A0709	COG0140	phosphoribosyl-ATP diphosphatase activity
VC0395_A0709	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VC0395_A0710	COG1187	pseudouridine synthase activity
VC0395_A0712	COG1278	Cold shock
VC0395_A0713	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VC0395_A0714	COG0542	response to heat
VC0395_A0716	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VC0395_A0717	COG1454	alcohol dehydrogenase
VC0395_A0717	COG1012	belongs to the aldehyde dehydrogenase family
VC0395_A0718	COG1737	Transcriptional regulator
VC0395_A0719	COG0076	glutamate decarboxylase activity
VC0395_A0721	COG2431	L-lysine efflux transmembrane transporter activity
VC0395_A0723	COG3070	regulator of competence-specific genes
VC0395_A0726	COG3852	Histidine kinase
VC0395_A0728	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VC0395_A0731	COG0189	ligase activity
VC0395_A0731	COG4067	protein conserved in archaea
VC0395_A0732	COG0500	methyltransferase
VC0395_A0733	COG4106	trans-aconitate 2-methyltransferase activity
VC0395_A0734	COG1801	Protein of unknown function DUF72
VC0395_A0735	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VC0395_A0736	COG1435	thymidine kinase activity
VC0395_A0737	COG1301	dicarboxylic acid transport
VC0395_A0740	COG3778	Protein conserved in bacteria
VC0395_A0741	COG3299	homolog of phage Mu protein gp47
VC0395_A0743	COG4384	Bacteriophage Mu Gp45 protein
VC0395_A0747	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
VC0395_A0749	COG4386	tail sheath protein
VC0395_A0753	COG4387	Mu-like prophage protein GP36
VC0395_A0755	COG4397	Mu-like prophage major head subunit gpT
VC0395_A0763	COG4383	Mu-like prophage protein gp29
VC0395_A0764	COG4373	Mu-like prophage FluMu protein gp28
VC0395_A0766	COG0640	Transcriptional regulator
VC0395_A0786	COG2842	Transposition protein
VC0395_A0787	COG2801	Transposase and inactivated derivatives
VC0395_A0788	COG3423	Transcriptional regulator
VC0395_A0791	COG0159	tryptophan synthase activity
VC0395_A0792	COG0133	tryptophan synthase activity
VC0395_A0793	COG0135	phosphoribosylanthranilate isomerase activity
VC0395_A0793	COG0134	indole-3-glycerol-phosphate synthase activity
VC0395_A0794	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VC0395_A0795	COG0512	Glutamine amidotransferase of anthranilate synthase
VC0395_A0796	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VC0395_A0798	COG0613	PHP domain protein
VC0395_A0799	COG0009	L-threonylcarbamoyladenylate synthase
VC0395_A0800	COG1187	pseudouridine synthase activity
VC0395_A0801	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VC0395_A0802	COG4988	ABC transporter
VC0395_A0803	COG0492	ferredoxin-NADP+ reductase activity
VC0395_A0806	COG3706	GGDEF domain
VC0395_A0807	COG2949	membrane
VC0395_A0809	COG0281	malic enzyme
VC0395_A0811	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VC0395_A0815	COG2885	chlorophyll binding
VC0395_A0818	COG0277	FAD linked oxidase domain protein
VC0395_A0818	COG0247	lactate metabolic process
VC0395_A0822	COG2986	histidine ammonia-lyase
VC0395_A0823	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VC0395_A0824	COG0010	Belongs to the arginase family
VC0395_A0825	COG1228	amidohydrolase
VC0395_A0829	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VC0395_A0831	COG0417	DNA replication proofreading
VC0395_A0832	COG5001	Diguanylate cyclase
VC0395_A0833	COG2197	response regulator
VC0395_A0834	COG0322	excinuclease ABC activity
VC0395_A0841	COG3706	GGDEF domain
VC0395_A0841	COG0745	RESPONSE REGULATOR receiver
VC0395_A0843	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VC0395_A0844	COG0072	phenylalanine-tRNA ligase activity
VC0395_A0844	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VC0395_A0846	COG0776	regulation of translation
VC0395_A0849	COG0500	methyltransferase
VC0395_A0852	COG0295	cytidine deaminase activity
VC0395_A0853	COG1346	cytolysis
VC0395_A0855	COG2925	Exonuclease
VC0395_A0857	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VC0395_A0859	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VC0395_A0860	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VC0395_A0863	COG2988	succinylglutamate desuccinylase activity
VC0395_A0864	COG4139	cobalamin transport
VC0395_A0865	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
VC0395_A0874	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VC0395_A0875	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VC0395_A0876	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VC0395_A0880	COG2814	Major facilitator Superfamily
VC0395_A0882	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VC0395_A0888	COG3108	Peptidase M15
VC0395_A0890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VC0395_A0892	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VC0395_A0897	COG1846	Transcriptional regulator
VC0395_A0898	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VC0395_A0899	COG0726	polysaccharide deacetylase
VC0395_A0900	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VC0395_A0902	COG1447	Phosphotransferase system cellobiose-specific component IIA
VC0395_A0903	COG1486	melibiose metabolic process
VC0395_A0904	COG3394	polysaccharide catabolic process
VC0395_A0905	COG1609	Transcriptional regulator
VC0395_A0906	COG2943	transferase activity, transferring hexosyl groups
VC0395_A0907	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
VC0395_A0908	COG0840	transmembrane signaling receptor activity
VC0395_A0911	COG1448	Aminotransferase
VC0395_A0913	COG3437	response regulator, receiver
VC0395_A0913	COG2770	Histidine kinase
VC0395_A0914	COG0351	phosphomethylpyrimidine kinase
VC0395_A0914	COG0352	thiamine-phosphate diphosphorylase activity
VC0395_A0915	COG0017	Asparaginyl-tRNA synthetase
VC0395_A0917	COG0720	synthase
VC0395_A0918	COG1760	l-serine dehydratase
VC0395_A0919	COG0814	amino acid
VC0395_A0920	COG0494	nUDIX hydrolase
VC0395_A0921	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VC0395_A0924	COG3106	COG3106 Predicted ATPase
VC0395_A0925	COG3768	UPF0283 membrane protein
VC0395_A0926	COG3283	Transcriptional regulator of aromatic amino acids metabolism
VC0395_A0927	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VC0395_A0930	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VC0395_A0932	COG0471	metal ion transport
VC0395_A0933	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VC0395_A0933	COG4191	Histidine kinase
VC0395_A0935	COG2990	Protein conserved in bacteria
VC0395_A0936	COG3713	MltA-interacting MipA family protein
VC0395_A0937	COG2205	protein histidine kinase activity
VC0395_A0938	COG0745	RESPONSE REGULATOR receiver
VC0395_A0944	COG1129	ABC transporter
VC0395_A0951	COG2186	Transcriptional regulator
VC0395_A0952	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VC0395_A0953	COG0372	Belongs to the citrate synthase family
VC0395_A0959	COG2195	Cleaves the N-terminal amino acid of tripeptides
VC0395_A0961	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VC0395_A0963	COG3437	response regulator, receiver
VC0395_A0964	COG0625	glutathione transferase activity
VC0395_A0965	COG3437	response regulator, receiver
VC0395_A0965	COG3850	Histidine kinase
VC0395_A0965	COG4999	Histidine kinase
VC0395_A0965	COG2205	protein histidine kinase activity
VC0395_A0967	COG3706	GGDEF domain
VC0395_A0968	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VC0395_A0969	COG1254	Belongs to the acylphosphatase family
VC0395_A0970	COG2920	part of a sulfur-relay system
VC0395_A0971	COG0670	Belongs to the BI1 family
VC0395_A0972	COG1126	abc transporter atp-binding protein
VC0395_A0973	COG0765	amino acid transport
VC0395_A0974	COG4597	amino acid ABC transporter
VC0395_A0975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VC0395_A0977	COG0561	phosphatase activity
VC0395_A0978	COG0602	queuosine metabolic process
VC0395_A0980	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VC0395_A0985	COG3706	GGDEF domain
VC0395_A0986	COG0443	Heat shock 70 kDa protein
VC0395_A0997	COG1643	Atp-dependent helicase
VC0395_A0999	COG0443	Heat shock 70 kDa protein
VC0395_A1000	COG0095	Lipoate-protein ligase
VC0395_A1001	COG0583	DNA-binding transcription factor activity
VC0395_A1003	COG0477	Major facilitator Superfamily
VC0395_A1004	COG0415	Belongs to the DNA photolyase family
VC0395_A1005	COG2076	Multidrug Resistance protein
VC0395_A1009	COG2198	Histidine kinase
VC0395_A1009	COG0643	Histidine kinase
VC0395_A1011	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VC0395_A1013	COG2201	protein-glutamate methylesterase activity
VC0395_A1014	COG0835	chemotaxis
VC0395_A1015	COG0840	transmembrane signaling receptor activity
VC0395_A1015	COG3290	protein histidine kinase activity
VC0395_A1016	COG0840	transmembrane signaling receptor activity
VC0395_A1018	COG0513	Belongs to the DEAD box helicase family
VC0395_A1020	COG1538	Outer membrane efflux protein
VC0395_A1021	COG1566	PFAM secretion protein HlyD family protein
VC0395_A1022	COG2814	Major facilitator Superfamily
VC0395_A1023	COG0840	transmembrane signaling receptor activity
VC0395_A1024	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VC0395_A1026	COG3501	Rhs element vgr protein
VC0395_A1031	COG1280	lysine exporter protein (LysE YggA)
VC0395_A1032	COG1115	amino acid carrier protein
VC0395_A1035	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VC0395_A1036	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VC0395_A1037	COG1177	transmembrane transport
VC0395_A1038	COG1176	ABC-type spermidine putrescine transport system, permease component I
VC0395_A1039	COG3842	ATPase activity
VC0395_A1043	COG0037	tRNA processing
VC0395_A1044	COG0589	response to stress
VC0395_A1045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VC0395_A1048	COG2217	Heavy metal translocating P-type atpase
VC0395_A1050	COG2010	Cytochrome c
VC0395_A1053	COG3278	Belongs to the heme-copper respiratory oxidase family
VC0395_A1055	COG2205	protein histidine kinase activity
VC0395_A1055	COG0784	Response regulator, receiver
VC0395_A1059	COG3064	Membrane
VC0395_A1059	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VC0395_A1059	COG1073	alpha beta
VC0395_A1061	COG4128	Pfam Zonular occludens toxin
VC0395_A1089	COG3120	sequence-specific DNA binding
VC0395_A1090	COG1067	ATP-dependent peptidase activity
VC0395_A1091	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VC0395_A1095	COG0116	Belongs to the methyltransferase superfamily
VC0395_A1095	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VC0395_A1098	COG0167	dihydroorotate dehydrogenase activity
VC0395_A1099	COG2902	Dehydrogenase
VC0395_A1102	COG0308	aminopeptidase N
VC0395_A1105	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VC0395_A1106	COG1956	GAF domain-containing protein
VC0395_A1107	COG1132	(ABC) transporter
VC0395_A1108	COG2995	paraquat-inducible protein a
VC0395_A1109	COG3008	intermembrane lipid transfer
VC0395_A1110	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
VC0395_A1110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VC0395_A1111	COG2996	Protein conserved in bacteria
VC0395_A1114	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VC0395_A1116	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VC0395_A1119	COG0437	4 iron, 4 sulfur cluster binding
VC0395_A1120	COG0243	molybdopterin cofactor binding
VC0395_A1120	COG3383	formate dehydrogenase (NAD+) activity
VC0395_A1126	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VC0395_A1127	COG0488	(ABC) transporter
VC0395_A1128	COG3852	Histidine kinase
VC0395_A1129	COG2204	response regulator
VC0395_A1131	COG4662	Binding-protein-dependent transport system inner membrane component
VC0395_A1132	COG3842	ATPase activity
VC0395_A1133	COG0746	molybdenum cofactor guanylyltransferase activity
VC0395_A1138	COG1940	carbohydrate kinase activity
VC0395_A1141	COG0840	transmembrane signaling receptor activity
VC0395_A1142	COG0791	NLP P60 protein
VC0395_A1146	COG0534	Mate efflux family protein
VC0395_A1148	COG1793	dna ligase
VC0395_A1150	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VC0395_A1151	COG0848	biopolymer transport protein
VC0395_A1152	COG0811	peptide transport
VC0395_A1153	COG0811	peptide transport
VC0395_A1156	COG1175	transmembrane transport
VC0395_A1157	COG0395	ABC-type sugar transport system, permease component
VC0395_A1158	COG3842	ATPase activity
VC0395_A1159	COG1349	DNA-binding transcription factor activity
VC0395_A1160	COG0584	glycerophosphoryl diester phosphodiesterase
VC0395_A1161	COG2731	YhcH YjgK YiaL family protein
VC0395_A1162	COG0251	oxidation-reduction process
VC0395_A1164	COG1609	Transcriptional regulator
VC0395_A1165	COG2723	6-phospho-beta-galactosidase activity
VC0395_A1166	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
VC0395_A1167	COG0583	DNA-binding transcription factor activity
VC0395_A1171	COG1136	(ABC) transporter
VC0395_A1171	COG0577	efflux transmembrane transporter activity
VC0395_A1172	COG0577	efflux transmembrane transporter activity
VC0395_A1172	COG1136	(ABC) transporter
VC0395_A1173	COG1136	(ABC) transporter
VC0395_A1173	COG4591	ABC-type transport system involved in lipoprotein release permease component
VC0395_A1174	COG1294	oxidase, subunit
VC0395_A1175	COG1271	oxidase subunit
VC0395_A1182	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VC0395_A1184	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VC0395_A1188	COG0753	catalase activity
VC0395_A1191	COG3527	Alpha-acetolactate decarboxylase
VC0395_A1194	COG2200	EAL domain
VC0395_A1194	COG2199	diguanylate cyclase activity
VC0395_A1195	COG3706	GGDEF domain
VC0395_A1196	COG2017	converts alpha-aldose to the beta-anomer
VC0395_A1197	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VC0395_A1198	COG1085	galactose-1-phosphate uridylyltransferase
VC0395_A1204	COG3706	GGDEF domain
VC0395_A1204	COG0745	RESPONSE REGULATOR receiver
VC0395_A1207	COG0835	chemotaxis
VC0395_A1207	COG0784	Response regulator, receiver
VC0395_A1209	COG4565	transcriptional regulatory protein
VC0395_A1210	COG3290	protein histidine kinase activity
VC0395_A1212	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VC0395_A1216	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VC0395_A1217	COG3063	Type IV pilus biogenesis stability protein PilW
VC0395_A1220	COG1943	Transposase
VC0395_A1222	COG1451	nucleotide metabolic process
VC0395_A1224	COG0583	DNA-binding transcription factor activity
VC0395_A1228	COG1538	Outer membrane efflux protein
VC0395_A1230	COG0019	diaminopimelate decarboxylase activity
VC0395_A1231	COG1748	Saccharopine dehydrogenase
VC0395_A1233	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VC0395_A1236	COG4181	ATPase activity
VC0395_A1237	COG0534	Mate efflux family protein
VC0395_A1238	COG0702	epimerase
VC0395_A1240	COG2814	Major facilitator Superfamily
VC0395_A1241	COG1187	pseudouridine synthase activity
VC0395_A1242	COG1061	Type III restriction enzyme res subunit
VC0395_A1246	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VC0395_A1247	COG2203	Gaf domain
VC0395_A1247	COG5001	Diguanylate cyclase
VC0395_A1247	COG4251	negative regulation of phosphorylation
VC0395_A1247	COG3706	GGDEF domain
VC0395_A1249	COG0840	transmembrane signaling receptor activity
VC0395_A1255	COG4934	collagen metabolic process
VC0395_A1256	COG4934	collagen metabolic process
VC0395_A1260	COG2239	Acts as a magnesium transporter
VC0395_A1262	COG0814	amino acid
VC0395_A1263	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VC0395_A1264	COG1131	(ABC) transporter
VC0395_A1265	COG0842	Transport permease protein
VC0395_A1267	COG3313	Fe-S protein
VC0395_A1269	COG4134	Bacterial extracellular solute-binding protein
VC0395_A1270	COG4135	transport system, permease component
VC0395_A1271	COG4136	ATPase activity
VC0395_A1272	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VC0395_A1273	COG0564	pseudouridine synthase activity
VC0395_A1274	COG0733	neurotransmitter:sodium symporter activity
VC0395_A1276	COG0626	cystathionine gamma-synthase activity
VC0395_A1277	COG2818	Glycosylase
VC0395_A1280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VC0395_A1283	COG1842	Phage shock protein A
VC0395_A1284	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VC0395_A1285	COG0747	negative chemotaxis
VC0395_A1286	COG4168	peptide transport system, permease
VC0395_A1287	COG4171	peptide transport system, permease
VC0395_A1289	COG4172	Belongs to the ABC transporter superfamily
VC0395_A1292	COG1227	inorganic diphosphatase activity
VC0395_A1296	COG0243	molybdopterin cofactor binding
VC0395_A1297	COG3005	denitrification pathway
VC0395_A1298	COG4459	periplasmic nitrate reductase
VC0395_A1299	COG2116	formate transmembrane transporter activity
VC0395_A1301	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VC0395_A1302	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VC0395_A1304	COG2917	probably involved in intracellular septation
VC0395_A1305	COG1607	acyl-coa hydrolase
VC0395_A1306	COG2350	Protein conserved in bacteria
VC0395_A1308	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VC0395_A1309	COG0583	DNA-binding transcription factor activity
VC0395_A1312	COG0612	Peptidase, M16
VC0395_A1313	COG5001	Diguanylate cyclase
VC0395_A1314	COG1032	radical SAM domain protein
VC0395_A1317	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
VC0395_A1318	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VC0395_A1319	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VC0395_A1320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VC0395_A1321	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VC0395_A1322	COG0745	RESPONSE REGULATOR receiver
VC0395_A1323	COG3381	protein complex oligomerization
VC0395_A1324	COG1609	Transcriptional regulator
VC0395_A1325	COG3070	regulator of competence-specific genes
VC0395_A1329	COG0297	glycogen (starch) synthase activity
VC0395_A1330	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VC0395_A1332	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VC0395_A1334	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
VC0395_A1336	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VC0395_A1337	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
VC0395_A1338	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VC0395_A1339	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VC0395_A1340	COG1960	acyl-CoA dehydrogenase activity
VC0395_A1344	COG1012	belongs to the aldehyde dehydrogenase family
VC0395_A1346	COG1309	transcriptional regulator
VC0395_A1350	COG0668	transmembrane transport
VC0395_A1351	COG2995	paraquat-inducible protein a
VC0395_A1352	COG3008	intermembrane lipid transfer
VC0395_A1352	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VC0395_A1354	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VC0395_A1357	COG0582	viral genome integration into host DNA
VC0395_A1358	COG0582	viral genome integration into host DNA
VC0395_A1359	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VC0395_A1363	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VC0395_A1367	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VC0395_A1371	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VC0395_A1372	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VC0395_A1373	COG1737	Transcriptional regulator
VC0395_A1374	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VC0395_A1375	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VC0395_A1376	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VC0395_A1377	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VC0395_A1378	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
VC0395_A1379	COG1940	carbohydrate kinase activity
VC0395_A1380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VC0395_A1381	COG4409	exo-alpha-(2->6)-sialidase activity
VC0395_A1383	COG2003	Belongs to the UPF0758 family
VC0395_A1388	COG3941	tape measure
VC0395_A1395	COG0488	(ABC) transporter
VC0395_A1410	COG0415	Belongs to the DNA photolyase family
VC0395_A1412	COG4628	conserved protein (DUF2132)
VC0395_A1413	COG3284	Transcriptional regulator
VC0395_A1414	COG1012	belongs to the aldehyde dehydrogenase family
VC0395_A1416	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VC0395_A1417	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VC0395_A1418	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VC0395_A1419	COG2207	Transcriptional regulator
VC0395_A1421	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VC0395_A1421	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VC0395_A1421	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VC0395_A1422	COG1482	cell wall glycoprotein biosynthetic process
VC0395_A1424	COG0784	Response regulator, receiver
VC0395_A1424	COG5002	protein histidine kinase activity
VC0395_A1426	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VC0395_A1428	COG2885	chlorophyll binding
VC0395_A1429	COG0823	Involved in the tonB-independent uptake of proteins
VC0395_A1432	COG0811	peptide transport
VC0395_A1434	COG1294	oxidase, subunit
VC0395_A1435	COG1271	oxidase subunit
VC0395_A1436	COG2255	four-way junction helicase activity
VC0395_A1437	COG0632	four-way junction helicase activity
VC0395_A1438	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VC0395_A1439	COG0215	cysteine-tRNA ligase activity
VC0395_A1440	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VC0395_A1441	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VC0395_A1442	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VC0395_A1444	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VC0395_A1445	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VC0395_A1446	COG1199	ATP-dependent helicase activity
VC0395_A1447	COG0730	response to heat
VC0395_A1448	COG3923	Primosomal replication protein n
VC0395_A1450	COG0840	transmembrane signaling receptor activity
VC0395_A1451	COG0708	Exodeoxyribonuclease III
VC0395_A1452	COG4160	amino acid transport
VC0395_A1453	COG4215	(ABC) transporter
VC0395_A1457	COG1882	Formate acetyltransferase
VC0395_A1459	COG0840	transmembrane signaling receptor activity
VC0395_A1460	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VC0395_A1462	COG3013	Belongs to the UPF0304 family
VC0395_A1463	COG2766	serine protein kinase
VC0395_A1464	COG2718	Belongs to the UPF0229 family
VC0395_A1465	COG2719	SpoVR family
VC0395_A1466	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VC0395_A1468	COG1663	tetraacyldisaccharide 4'-kinase activity
VC0395_A1469	COG1132	(ABC) transporter
VC0395_A1470	COG2333	competence protein COMEC
VC0395_A1470	COG0658	competence protein
VC0395_A1472	COG4591	ABC-type transport system involved in lipoprotein release permease component
VC0395_A1473	COG1136	(ABC) transporter
VC0395_A1474	COG4591	ABC-type transport system involved in lipoprotein release permease component
VC0395_A1476	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VC0395_A1480	COG1252	NADH dehydrogenase
VC0395_A1487	COG0537	adenosine 5'-monophosphoramidase activity
VC0395_A1490	COG2186	Transcriptional regulator
VC0395_A1491	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VC0395_A1492	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VC0395_A1493	COG1674	ftsk spoiiie
VC0395_A1495	COG0686	Belongs to the AlaDH PNT family
VC0395_A1497	COG0583	DNA-binding transcription factor activity
VC0395_A1501	COG0284	orotidine-5'-phosphate decarboxylase activity
VC0395_A1502	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VC0395_A1503	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VC0395_A1504	COG0776	regulation of translation
VC0395_A1505	COG0539	negative regulation of cytoplasmic translation
VC0395_A1506	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VC0395_A1507	COG1555	photosystem II stabilization
VC0395_A1508	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VC0395_A1509	COG0776	regulation of translation
VC0395_A1510	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VC0395_A1511	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VC0395_A1512	COG0740	serine-type endopeptidase activity
VC0395_A1513	COG0544	peptidyl-prolyl cis-trans isomerase activity
VC0395_A1515	COG4191	Histidine kinase
VC0395_A1517	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VC0395_A1518	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VC0395_A1519	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VC0395_A1520	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VC0395_A1523	COG5001	Diguanylate cyclase
VC0395_A1523	COG3300	MHYT domain
VC0395_A1525	COG4589	Belongs to the CDS family
VC0395_A1533	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VC0395_A1535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VC0395_A1538	COG0243	molybdopterin cofactor binding
VC0395_A1539	COG3005	denitrification pathway
VC0395_A1540	COG3325	Belongs to the glycosyl hydrolase 18 family
VC0395_A1540	COG3469	chitinase activity
VC0395_A1541	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VC0395_A1543	COG2951	lytic endotransglycosylase activity
VC0395_A1544	COG3100	YcgL domain-containing protein
VC0395_A1545	COG0850	regulation of cytokinetic process
VC0395_A1546	COG2894	cell division
VC0395_A1547	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VC0395_A1548	COG3015	lipoprotein NlpE involved in copper resistance
VC0395_A1552	COG0477	Major facilitator Superfamily
VC0395_A1554	COG0840	transmembrane signaling receptor activity
VC0395_A1555	COG1396	sequence-specific DNA binding
VC0395_A1556	COG3135	benzoate transporter
VC0395_A1558	COG1441	menaquinone biosynthetic process
VC0395_A1560	COG0596	Alpha beta hydrolase
VC0395_A1561	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VC0395_A1562	COG1169	isochorismate synthase
VC0395_A1563	COG0436	Aminotransferase
VC0395_A1564	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VC0395_A1566	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VC0395_A1569	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VC0395_A1570	COG0318	PFAM AMP-dependent synthetase and ligase
VC0395_A1571	COG0596	Alpha beta hydrolase
VC0395_A1574	COG1214	PFAM Peptidase M22, glycoprotease
VC0395_A1575	COG1199	ATP-dependent helicase activity
VC0395_A1577	COG0788	formyltetrahydrofolate deformylase activity
VC0395_A1578	COG1902	pentaerythritol trinitrate reductase activity
VC0395_A1578	COG0446	pyridine nucleotide-disulphide oxidoreductase
VC0395_A1579	COG0616	signal peptide processing
VC0395_A1580	COG0252	asparaginase activity
VC0395_A1581	COG3139	Protein of unknown function (DUF1315)
VC0395_A1584	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VC0395_A1586	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VC0395_A1587	COG0676	glucose-6-phosphate 1-epimerase activity
VC0395_A1589	COG2226	methyltransferase
VC0395_A1592	COG0835	chemotaxis
VC0395_A1592	COG0784	Response regulator, receiver
VC0395_A1593	COG1940	carbohydrate kinase activity
VC0395_A1595	COG4667	esterase of the alpha-beta hydrolase superfamily
VC0395_A1598	COG0733	neurotransmitter:sodium symporter activity
VC0395_A1599	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VC0395_A1599	COG1263	PTS System
VC0395_A1600	COG0084	hydrolase, TatD family'
VC0395_A1602	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VC0395_A1603	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VC0395_A1604	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VC0395_A1605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VC0395_A1606	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VC0395_A1607	COG1028	Short-chain dehydrogenase reductase Sdr
VC0395_A1608	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
VC0395_A1609	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VC0395_A1610	COG0416	fatty acid biosynthetic process
VC0395_A1611	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VC0395_A1612	COG1399	metal-binding, possibly nucleic acid-binding protein
VC0395_A1613	COG0424	maF-like protein
VC0395_A1614	COG0564	pseudouridine synthase activity
VC0395_A1615	COG1530	ribonuclease E activity
VC0395_A1617	COG0659	secondary active sulfate transmembrane transporter activity
VC0395_A1619	COG1012	belongs to the aldehyde dehydrogenase family
VC0395_A1619	COG1454	alcohol dehydrogenase
VC0395_A1620	COG2095	MarC family integral membrane protein
VC0395_A1621	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VC0395_A1622	COG1757	Na H antiporter
VC0395_A1624	COG3081	Nucleoid-associated protein
VC0395_A1626	COG3083	sulfuric ester hydrolase activity
VC0395_A1629	COG0123	including yeast histone deacetylase and acetoin utilization protein
VC0395_A1630	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VC0395_A1631	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VC0395_A1636	COG2853	Lipoprotein
VC0395_A1638	COG3088	subunit of a heme lyase
VC0395_A1638	COG4235	cytochrome complex assembly
VC0395_A1639	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VC0395_A1640	COG1138	Cytochrome C-type biogenesis protein
VC0395_A1641	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VC0395_A1643	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VC0395_A1644	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VC0395_A1645	COG4133	protoheme IX ABC transporter activity
VC0395_A1647	COG0835	chemotaxis
VC0395_A1649	COG1192	Involved in chromosome partitioning
VC0395_A1650	COG2201	protein-glutamate methylesterase activity
VC0395_A1651	COG0643	Histidine kinase
VC0395_A1651	COG2198	Histidine kinase
VC0395_A1652	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VC0395_A1655	COG0455	bacterial-type flagellum organization
VC0395_A1658	COG2062	phosphohistidine phosphatase, SixA
VC0395_A1660	COG1025	Belongs to the peptidase M16 family
VC0395_A1661	COG0018	arginyl-trna synthetase
VC0395_A1665	COG1918	ferrous iron import across plasma membrane
VC0395_A1666	COG4977	sequence-specific DNA binding
VC0395_A1667	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VC0395_A1668	COG1121	(ABC) transporter
VC0395_A1669	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VC0395_A1671	COG0045	succinate-CoA ligase (ADP-forming) activity
VC0395_A1672	COG0508	dehydrogenase complex catalyzes the overall conversion of
VC0395_A1673	COG0567	Dehydrogenase, E1 component
VC0395_A1675	COG1053	succinate dehydrogenase
VC0395_A1676	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VC0395_A1677	COG2009	succinate dehydrogenase
VC0395_A1678	COG0372	Belongs to the citrate synthase family
VC0395_A1679	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VC0395_A1681	COG0033	Phosphoglucomutase
VC0395_A1682	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VC0395_A1683	COG0596	Alpha beta hydrolase
VC0395_A1686	COG1346	cytolysis
VC0395_A1688	COG0583	DNA-binding transcription factor activity
VC0395_A1690	COG0735	belongs to the Fur family
VC0395_A1691	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VC0395_A1692	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VC0395_A1693	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VC0395_A1694	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VC0395_A1694	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VC0395_A1695	COG0431	NADPH-dependent FMN reductase
VC0395_A1697	COG3101	peptidyl-lysine hydroxylation
VC0395_A1698	COG2860	membrane
VC0395_A1699	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VC0395_A1700	COG2890	protein-(glutamine-N5) methyltransferase activity
VC0395_A1703	COG1684	flagellar biosynthetic protein fliR
VC0395_A1704	COG1987	bacterial-type flagellum assembly
VC0395_A1710	COG1580	Controls the rotational direction of flagella during chemotaxis
VC0395_A1715	COG1317	bacterial-type flagellum organization
VC0395_A1716	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VC0395_A1718	COG1677	Flagellar hook-basal body complex protein FliE
VC0395_A1719	COG2204	response regulator
VC0395_A1720	COG4191	Histidine kinase
VC0395_A1721	COG2204	response regulator
VC0395_A1722	COG1516	flagellar protein fliS
VC0395_A1724	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VC0395_A1725	COG1334	flagellar protein FlaG
VC0395_A1726	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VC0395_A1727	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VC0395_A1728	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VC0395_A1729	COG2837	iron assimilation
VC0395_A1733	COG1393	Belongs to the ArsC family
VC0395_A1734	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VC0395_A1735	COG1876	peptidase activity
VC0395_A1737	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VC0395_A1738	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VC0395_A1740	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VC0395_A1744	COG4783	chaperone-mediated protein folding
VC0395_A1745	COG1393	Belongs to the ArsC family
VC0395_A1749	COG2233	PERMEase
VC0395_A1750	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VC0395_A1751	COG0737	Belongs to the 5'-nucleotidase family
VC0395_A1752	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VC0395_A1753	COG2912	Transglutaminase-like superfamily
VC0395_A1754	COG3094	Invasion gene expression up-regulator, SirB
VC0395_A1755	COG2890	protein-(glutamine-N5) methyltransferase activity
VC0395_A1756	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VC0395_A1757	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VC0395_A1758	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VC0395_A1759	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VC0395_A1760	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VC0395_A1761	COG0193	aminoacyl-tRNA hydrolase activity
VC0395_A1762	COG0012	GTP binding
VC0395_A1777	COG1943	Transposase
VC0395_A1779	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VC0395_A1780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VC0395_A1784	COG1705	Flagellar rod assembly protein muramidase FlgJ
VC0395_A1784	COG3951	Flagellar rod assembly protein muramidase FlgJ
VC0395_A1785	COG1706	bacterial-type flagellum-dependent cell motility
VC0395_A1786	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VC0395_A1787	COG4786	Flagellar basal body rod
VC0395_A1788	COG4787	bacterial-type flagellum-dependent cell motility
VC0395_A1789	COG1749	Flagellar hook protein flgE
VC0395_A1790	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
VC0395_A1791	COG1558	bacterial-type flagellum-dependent cell motility
VC0395_A1792	COG1815	bacterial-type flagellum-dependent cell motility
VC0395_A1793	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VC0395_A1794	COG0835	chemotaxis
VC0395_A1794	COG0784	Response regulator, receiver
VC0395_A1801	COG3433	isochorismatase activity
VC0395_A1801	COG2226	methyltransferase
VC0395_A1801	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VC0395_A1802	COG2375	cellular response to nickel ion
VC0395_A1803	COG4774	siderophore transport
VC0395_A1803	COG1629	transport
VC0395_A1806	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VC0395_A1807	COG2217	Heavy metal translocating P-type atpase
VC0395_A1807	COG2608	mercury ion transmembrane transporter activity
VC0395_A1812	COG3735	TraB family
VC0395_A1815	COG2840	Smr protein MutS2
VC0395_A1816	COG1187	pseudouridine synthase activity
VC0395_A1817	COG3706	GGDEF domain
VC0395_A1818	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VC0395_A1819	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VC0395_A1820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VC0395_A1821	COG0121	glutamine amidotransferase
VC0395_A1822	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VC0395_A1823	COG1960	acyl-CoA dehydrogenase activity
VC0395_A1825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VC0395_A1826	COG0328	RNA-DNA hybrid ribonuclease activity
VC0395_A1827	COG2226	methyltransferase
VC0395_A1828	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VC0395_A1829	COG0741	lytic transglycosylase activity
VC0395_A1829	COG1388	LysM domain
VC0395_A1831	COG0347	Belongs to the P(II) protein family
VC0395_A1832	COG3479	Phenolic acid decarboxylase
VC0395_A1834	COG0037	tRNA processing
VC0395_A1835	COG0825	malonyl-CoA metabolic process
VC0395_A1836	COG0587	DNA-directed DNA polymerase activity
VC0395_A1837	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
VC0395_A1838	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VC0395_A1839	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VC0395_A1840	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VC0395_A1841	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VC0395_A1842	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VC0395_A1844	COG0750	zinc metalloprotease
VC0395_A1845	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VC0395_A1846	COG0575	Belongs to the CDS family
VC0395_A1847	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VC0395_A1848	COG0233	cytoplasmic translational termination
VC0395_A1849	COG0528	UMP kinase activity
VC0395_A1850	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VC0395_A1851	COG0052	Belongs to the universal ribosomal protein uS2 family
VC0395_A1852	COG0024	Methionine aminopeptidase
VC0395_A1853	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VC0395_A1855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VC0395_A1856	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VC0395_A1857	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VC0395_A1858	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VC0395_A1861	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VC0395_A1861	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VC0395_A1862	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VC0395_A1863	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VC0395_A1864	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VC0395_A1867	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VC0395_A1868	COG2252	PERMEase
VC0395_A1869	COG2195	Cleaves the N-terminal amino acid of tripeptides
VC0395_A1870	COG0189	ligase activity
VC0395_A1870	COG4067	protein conserved in archaea
VC0395_A1871	COG0189	ligase activity
VC0395_A1873	COG0733	neurotransmitter:sodium symporter activity
VC0395_A1874	COG3706	GGDEF domain
VC0395_A1876	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VC0395_A1878	COG1477	protein flavinylation
VC0395_A1879	COG2871	sodium ion transport
VC0395_A1880	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VC0395_A1881	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VC0395_A1882	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VC0395_A1883	COG1805	sodium ion transport
VC0395_A1884	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VC0395_A1885	COG0271	Belongs to the BolA IbaG family
VC0395_A1886	COG2813	Specifically methylates the guanine in position
VC0395_A1888	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VC0395_A1889	COG2211	Major facilitator Superfamily
VC0395_A1891	COG1595	DNA-templated transcription, initiation
VC0395_A1893	COG3248	Nucleoside-binding outer membrane protein
VC0395_A1894	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VC0395_A1895	COG0693	protein deglycase activity
VC0395_A1896	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VC0395_A1897	COG2166	iron-sulfur cluster assembly
VC0395_A1898	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VC0395_A1899	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VC0395_A1901	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VC0395_A1901	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VC0395_A1903	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VC0395_A1904	COG1074	ATP-dependent DNA helicase activity
VC0395_A1905	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VC0395_A1908	COG3141	response to X-ray
VC0395_A1909	COG2171	N-acyltransferase activity
VC0395_A1911	COG0456	acetyltransferase
VC0395_A1912	COG0189	ligase activity
VC0395_A1912	COG0569	domain protein
VC0395_A1914	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VC0395_A1917	COG3250	beta-galactosidase activity
VC0395_A1920	COG1022	Amp-dependent synthetase and ligase
VC0395_A1921	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VC0395_A1922	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VC0395_A1924	COG0560	Phosphoserine phosphatase
VC0395_A1926	COG0813	purine-nucleoside phosphorylase activity
VC0395_A1927	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VC0395_A1928	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VC0395_A1929	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VC0395_A1931	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VC0395_A1932	COG0084	hydrolase, TatD family'
VC0395_A1935	COG1115	amino acid carrier protein
VC0395_A1938	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VC0395_A1939	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VC0395_A1940	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VC0395_A1941	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VC0395_A1942	COG0083	homoserine kinase activity
VC0395_A1944	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VC0395_A1947	COG0745	RESPONSE REGULATOR receiver
VC0395_A1948	COG0784	Response regulator, receiver
VC0395_A1948	COG2198	Histidine kinase
VC0395_A1948	COG5002	protein histidine kinase activity
VC0395_A1949	COG5001	Diguanylate cyclase
VC0395_A1949	COG4251	negative regulation of phosphorylation
VC0395_A1949	COG2203	Gaf domain
VC0395_A1949	COG3706	GGDEF domain
VC0395_A1950	COG1242	4 iron, 4 sulfur cluster binding
VC0395_A1952	COG0070	glutamate synthase
VC0395_A1952	COG0069	glutamate synthase activity
VC0395_A1952	COG0067	glutamate synthase
VC0395_A1954	COG0070	glutamate synthase
VC0395_A1954	COG0069	glutamate synthase activity
VC0395_A1954	COG0067	glutamate synthase
VC0395_A1955	COG0493	'glutamate synthase
VC0395_A1957	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VC0395_A1959	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VC0395_A1960	COG2860	membrane
VC0395_A1961	COG0730	response to heat
VC0395_A1963	COG4172	Belongs to the ABC transporter superfamily
VC0395_A1967	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VC0395_A1968	COG0505	Belongs to the CarA family
VC0395_A1970	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
VC0395_A1971	COG0494	nUDIX hydrolase
VC0395_A1972	COG0653	protein targeting
VC0395_A1974	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VC0395_A1975	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VC0395_A1976	COG0849	cell division
VC0395_A1977	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VC0395_A1978	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VC0395_A1979	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
VC0395_A1980	COG0772	Belongs to the SEDS family
VC0395_A1981	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VC0395_A1982	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VC0395_A1983	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VC0395_A1984	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VC0395_A1985	COG0768	penicillin binding
VC0395_A1986	COG3116	cell division
VC0395_A1987	COG0275	rRNA processing
VC0395_A1988	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VC0395_A1989	COG0508	dehydrogenase complex catalyzes the overall conversion of
VC0395_A1990	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VC0395_A1991	COG2186	Transcriptional regulator
VC0395_A1992	COG0737	Belongs to the 5'-nucleotidase family
VC0395_A1993	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VC0395_A1994	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VC0395_A1995	COG4974	Belongs to the 'phage' integrase family
VC0395_A1996	COG0716	FMN binding
VC0395_A2000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VC0395_A2001	COG1459	type II secretion system
VC0395_A2003	COG0237	dephospho-CoA kinase activity
VC0395_A2005	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VC0395_A2006	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
VC0395_A2007	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VC0395_A2008	COG0187	DNA topoisomerase II activity
VC0395_A2009	COG3150	esterase
VC0395_A2011	COG3151	Protein conserved in bacteria
VC0395_A2012	COG0494	nUDIX hydrolase
VC0395_A2013	COG1538	Outer membrane efflux protein
VC0395_A2014	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
VC0395_A2014	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
VC0395_A2015	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VC0395_A2016	COG0840	transmembrane signaling receptor activity
VC0395_A2018	COG3025	triphosphatase activity
VC0395_A2019	COG1392	Phosphate transport regulator
VC0395_A2020	COG0306	phosphate transporter
VC0395_A2021	COG4991	sh3 domain protein
VC0395_A2023	COG3409	Peptidoglycan-binding domain 1 protein
VC0395_A2023	COG3267	Type II secretory pathway component ExeA
VC0395_A2024	COG0617	tRNA 3'-terminal CCA addition
VC0395_A2025	COG0148	phosphopyruvate hydratase activity
VC0395_A2026	COG0504	CTP synthase activity
VC0395_A2028	COG3956	TIGRFAM MazG family protein
VC0395_A2029	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VC0395_A2030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VC0395_A2035	COG0736	holo-[acyl-carrier-protein] synthase activity
VC0395_A2036	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VC0395_A2037	COG1381	Involved in DNA repair and RecF pathway recombination
VC0395_A2038	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VC0395_A2039	COG0571	ribonuclease III activity
VC0395_A2040	COG0681	Belongs to the peptidase S26 family
VC0395_A2041	COG0481	GTPase activity
VC0395_A2042	COG3086	response to oxidative stress
VC0395_A2043	COG3026	antisigma factor binding
VC0395_A2045	COG1595	DNA-templated transcription, initiation
VC0395_A2046	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VC0395_A2048	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VC0395_A2049	COG0354	folic acid binding
VC0395_A2051	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VC0395_A2052	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VC0395_A2054	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VC0395_A2055	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VC0395_A2056	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VC0395_A2057	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VC0395_A2058	COG0440	acetolactate synthase activity
VC0395_A2059	COG0028	Belongs to the TPP enzyme family
VC0395_A2060	COG1022	Amp-dependent synthetase and ligase
VC0395_A2061	COG0583	DNA-binding transcription factor activity
VC0395_A2065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VC0395_A2066	COG0473	3-isopropylmalate dehydrogenase activity
VC0395_A2067	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
VC0395_A2068	COG0066	3-isopropylmalate dehydratase activity
VC0395_A2078	COG3437	response regulator, receiver
VC0395_A2081	COG0795	lipopolysaccharide-transporting ATPase activity
VC0395_A2082	COG0795	lipopolysaccharide-transporting ATPase activity
VC0395_A2083	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VC0395_A2084	COG2927	DNA polymerase III (CHI subunit)
VC0395_A2085	COG0525	valine-tRNA ligase activity
VC0395_A2086	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VC0395_A2087	COG0564	pseudouridine synthase activity
VC0395_A2088	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VC0395_A2090	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VC0395_A2091	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
VC0395_A2092	COG0540	Belongs to the ATCase OTCase family
VC0395_A2093	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
VC0395_A2094	COG0251	oxidation-reduction process
VC0395_A2095	COG0204	Acyl-transferase
VC0395_A2096	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VC0395_A2097	COG5007	Belongs to the BolA IbaG family
VC0395_A2099	COG2854	intermembrane phospholipid transfer
VC0395_A2100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VC0395_A2101	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VC0395_A2102	COG1127	ABC transporter
VC0395_A2104	COG0517	IMP dehydrogenase activity
VC0395_A2104	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VC0395_A2107	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VC0395_A2108	COG1137	ATPase activity
VC0395_A2110	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VC0395_A2111	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VC0395_A2113	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VC0395_A2114	COG2239	Acts as a magnesium transporter
VC0395_A2115	COG0312	modulator of DNA gyrase
VC0395_A2116	COG3028	Belongs to the UPF0307 family
VC0395_A2117	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VC0395_A2118	COG1178	ABC-type Fe3 transport system permease component
VC0395_A2119	COG4143	(ABC) transporter
VC0395_A2120	COG0163	prenyltransferase activity
VC0395_A2121	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VC0395_A2122	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
VC0395_A2123	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VC0395_A2124	COG2105	PFAM AIG2 family protein
VC0395_A2126	COG0729	surface antigen
VC0395_A2127	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VC0395_A2128	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VC0395_A2131	COG1136	(ABC) transporter
VC0395_A2131	COG0577	efflux transmembrane transporter activity
VC0395_A2135	COG0529	Catalyzes the synthesis of activated sulfate
VC0395_A2136	COG2895	sulfate adenylyltransferase (ATP) activity
VC0395_A2137	COG0175	sulfate reduction
VC0395_A2138	COG1648	precorrin-2 dehydrogenase activity
VC0395_A2138	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VC0395_A2139	COG0737	Belongs to the 5'-nucleotidase family
VC0395_A2141	COG0513	Belongs to the DEAD box helicase family
VC0395_A2142	COG2153	protein acetylation
VC0395_A2143	COG0697	spore germination
VC0395_A2145	COG0545	Peptidyl-prolyl cis-trans isomerase
VC0395_A2146	COG1943	Transposase
VC0395_A2148	COG0203	ribosomal protein L17
VC0395_A2149	COG0202	RNA polymerase activity
VC0395_A2150	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VC0395_A2151	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VC0395_A2152	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VC0395_A2154	COG0201	protein transport
VC0395_A2155	COG0200	Binds to the 23S rRNA
VC0395_A2156	COG1841	ribosomal large subunit assembly
VC0395_A2157	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VC0395_A2158	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VC0395_A2159	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
VC0395_A2160	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VC0395_A2161	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VC0395_A2162	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VC0395_A2163	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VC0395_A2164	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VC0395_A2165	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VC0395_A2166	COG0255	Belongs to the universal ribosomal protein uL29 family
VC0395_A2167	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VC0395_A2168	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VC0395_A2169	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VC0395_A2170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VC0395_A2171	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VC0395_A2172	COG0089	rRNA binding
VC0395_A2173	COG0088	Forms part of the polypeptide exit tunnel
VC0395_A2174	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VC0395_A2175	COG0051	transcription antitermination factor activity, RNA binding
VC0395_A2176	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VC0395_A2177	COG0557	exoribonuclease II activity
VC0395_A2178	COG3083	sulfuric ester hydrolase activity
VC0395_A2179	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VC0395_A2180	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VC0395_A2182	COG1047	Peptidyl-prolyl cis-trans
VC0395_A2185	COG2249	NAD(P)H dehydrogenase (quinone) activity
VC0395_A2186	COG0488	(ABC) transporter
VC0395_A2188	COG0429	hydrolase of the alpha beta-hydrolase fold
VC0395_A2190	COG3954	Phosphoribulokinase
VC0395_A2191	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VC0395_A2193	COG1012	belongs to the aldehyde dehydrogenase family
VC0395_A2195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VC0395_A2197	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VC0395_A2200	COG0180	Tryptophanyl-tRNA synthetase
VC0395_A2201	COG0546	phosphoglycolate phosphatase activity
VC0395_A2202	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VC0395_A2203	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VC0395_A2205	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VC0395_A2206	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VC0395_A2212	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VC0395_A2214	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VC0395_A2214	COG0678	peroxiredoxin activity
VC0395_A2215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VC0395_A2217	COG0165	Argininosuccinate lyase
VC0395_A2218	COG0137	argininosuccinate synthase activity
VC0395_A2219	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VC0395_A2220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VC0395_A2221	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VC0395_A2222	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VC0395_A2225	COG1045	serine acetyltransferase
VC0395_A2226	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VC0395_A2227	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VC0395_A2228	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VC0395_A2229	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VC0395_A2230	COG1053	succinate dehydrogenase
VC0395_A2231	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VC0395_A2232	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VC0395_A2233	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VC0395_A2234	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VC0395_A2235	COG1509	lysine 2,3-aminomutase activity
VC0395_A2237	COG0459	protein refolding
VC0395_A2238	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VC0395_A2243	COG0149	triose-phosphate isomerase activity
VC0395_A2245	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VC0395_A2246	COG1575	Belongs to the MenA family. Type 1 subfamily
VC0395_A2247	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VC0395_A2248	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VC0395_A2249	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VC0395_A2250	COG1609	Transcriptional regulator
VC0395_A2251	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VC0395_A2252	COG0254	rRNA binding
VC0395_A2254	COG0281	malic enzyme
VC0395_A2255	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
VC0395_A2256	COG0626	cystathionine gamma-synthase activity
VC0395_A2257	COG0460	homoserine dehydrogenase
VC0395_A2257	COG0527	aspartate kinase activity
VC0395_A2258	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VC0395_A2259	COG3074	FtsZ-dependent cytokinesis
VC0395_A2260	COG1494	fructose-1,6-bisphosphatase
VC0395_A2261	COG0205	6-phosphofructokinase activity
VC0395_A2262	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VC0395_A2264	COG0745	RESPONSE REGULATOR receiver
VC0395_A2265	COG2205	protein histidine kinase activity
VC0395_A2267	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VC0395_A2268	COG3030	protein affecting phage T7 exclusion by the F plasmid
VC0395_A2269	COG3706	GGDEF domain
VC0395_A2270	COG1027	Aspartate ammonia-lyase
VC0395_A2271	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VC0395_A2274	COG4232	protein-disulfide reductase activity
VC0395_A2276	COG3263	regulation of cellular component size
VC0395_A2278	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VC0395_A2279	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VC0395_A2280	COG0194	GDP metabolic process
VC0395_A2281	COG1758	RNA polymerase activity
VC0395_A2282	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VC0395_A2283	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VC0395_A2284	COG2233	PERMEase
VC0395_A2286	COG0745	RESPONSE REGULATOR receiver
VC0395_A2287	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VC0395_A2288	COG2183	response to ionizing radiation
VC0395_A2290	COG0596	Alpha beta hydrolase
VC0395_A2292	COG1040	competence protein
VC0395_A2293	COG0316	Belongs to the HesB IscA family
VC0395_A2293	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
VC0395_A2294	COG0494	nUDIX hydrolase
VC0395_A2295	COG1218	3'(2'),5'-bisphosphate nucleotidase
VC0395_A2297	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VC0395_A2298	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VC0395_A2299	COG3156	type II secretion system protein K
VC0395_A2300	COG4795	General secretion pathway protein
VC0395_A2301	COG2165	general secretion pathway protein
VC0395_A2302	COG2165	general secretion pathway protein
VC0395_A2303	COG2165	general secretion pathway protein
VC0395_A2304	COG1459	type II secretion system
VC0395_A2305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VC0395_A2307	COG3031	protein transport across the cell outer membrane
VC0395_A2308	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VC0395_A2309	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VC0395_A2310	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
VC0395_A2312	COG0456	acetyltransferase
VC0395_A2313	COG1490	D-aminoacyl-tRNA deacylase activity
VC0395_A2315	COG1660	Displays ATPase and GTPase activities
VC0395_A2318	COG0174	glutamine synthetase
VC0395_A2320	COG3852	Histidine kinase
VC0395_A2322	COG5001	Diguanylate cyclase
VC0395_A2322	COG3300	MHYT domain
VC0395_A2323	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VC0395_A2339	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
VC0395_A2341	COG1404	Belongs to the peptidase S8 family
VC0395_A2342	COG4206	TonB-dependent receptor
VC0395_A2345	COG3335	DDE superfamily endonuclease
VC0395_A2351	COG3550	peptidyl-serine autophosphorylation
VC0395_A2362	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
VC0395_A2367	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VC0395_A2370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VC0395_A2371	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VC0395_A2372	COG2177	Part of the ABC transporter FtsEX involved in
VC0395_A2373	COG2884	Cell division ATP-binding protein ftsE
VC0395_A2374	COG0552	protein localization to endoplasmic reticulum
VC0395_A2375	COG0742	ribosomal rna small subunit methyltransferase
VC0395_A2381	COG0783	Belongs to the Dps family
VC0395_A2383	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VC0395_A2384	COG1280	lysine exporter protein (LysE YggA)
VC0395_A2385	COG2267	carboxylic ester hydrolase activity
VC0395_A2386	COG0561	phosphatase activity
VC0395_A2389	COG2199	diguanylate cyclase activity
VC0395_A2389	COG3287	FIST C domain
VC0395_A2389	COG2200	EAL domain
VC0395_A2390	COG1011	Hydrolase
VC0395_A2391	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VC0395_A2393	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VC0395_A2394	COG0019	diaminopimelate decarboxylase activity
VC0395_A2396	COG1965	Belongs to the frataxin family
VC0395_A2397	COG3072	Adenylate cyclase
VC0395_A2398	COG0181	hydroxymethylbilane synthase activity
VC0395_A2399	COG1587	Uroporphyrinogen-III synthase
VC0395_A2400	COG2959	enzyme of heme biosynthesis
VC0395_A2401	COG3071	HemY protein
VC0395_A2402	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VC0395_A2404	COG3078	GTPase activator activity
VC0395_A2407	COG0218	Necessary for normal cell division and for the maintenance of normal septation
VC0395_A2409	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VC0395_A2409	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VC0395_A2415	COG0084	hydrolase, TatD family'
VC0395_A2416	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VC0395_A2418	COG0840	transmembrane signaling receptor activity
VC0395_A2419	COG1580	Controls the rotational direction of flagella during chemotaxis
VC0395_A2420	COG3161	chorismate lyase activity
VC0395_A2421	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VC0395_A2422	COG2937	Belongs to the GPAT DAPAT family
VC0395_A2423	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VC0395_A2425	COG0534	Mate efflux family protein
VC0395_A2426	COG1858	cytochrome C peroxidase
VC0395_A2427	COG0805	protein transport
VC0395_A2428	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VC0395_A2429	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VC0395_A2430	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
VC0395_A2432	COG2226	methyltransferase
VC0395_A2433	COG1322	Protein conserved in bacteria
VC0395_A2434	COG2081	HI0933 family
VC0395_A2437	COG1528	Iron-storage protein
VC0395_A2438	COG0589	response to stress
VC0395_A2439	COG0697	spore germination
VC0395_A2441	COG0742	ribosomal rna small subunit methyltransferase
VC0395_A2442	COG5002	protein histidine kinase activity
VC0395_A2442	COG5001	Diguanylate cyclase
VC0395_A2443	COG1522	sequence-specific DNA binding
VC0395_A2447	COG0006	proline dipeptidase activity
VC0395_A2447	COG0006	proline dipeptidase activity
VC0395_A2448	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VC0395_A2449	COG2022	thiamine diphosphate biosynthetic process
VC0395_A2450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VC0395_A2452	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VC0395_A2453	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VC0395_A2463	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VC0395_A2464	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VC0395_A2465	COG0408	coproporphyrinogen oxidase activity
VC0395_A2466	COG0009	L-threonylcarbamoyladenylate synthase
VC0395_A2467	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VC0395_A2468	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VC0395_A2469	COG0551	DNA topoisomerase type I activity
VC0395_A2470	COG2922	Belongs to the Smg family
VC0395_A2471	COG0758	DNA mediated transformation
VC0395_A2472	COG1652	LysM domain
VC0395_A2473	COG0242	peptide deformylase activity
VC0395_A2474	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VC0395_A2475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VC0395_A2475	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VC0395_A2476	COG0569	domain protein
VC0395_A2477	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VC0395_A2479	COG1272	protein, Hemolysin III
VC0395_A2480	COG4326	sporulation control protein
VC0395_A2482	COG3084	Protein conserved in bacteria
VC0395_A2484	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VC0395_A2485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VC0395_A2486	COG0204	Acyl-transferase
VC0395_A2487	COG0606	chelatase, subunit chli
VC0395_A2490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VC0395_A2491	COG0129	dihydroxy-acid dehydratase activity
VC0395_A2493	COG0604	alcohol dehydrogenase
VC0395_A2495	COG0425	Belongs to the sulfur carrier protein TusA family
VC0395_A2497	COG2119	membrane
VC0395_A2498	COG0752	glycyl-tRNA synthetase alpha subunit
VC0395_A2499	COG0751	glycine-tRNA ligase activity
VC0395_A2500	COG3977	Valine--pyruvate aminotransferase
VC0395_A2501	COG0071	Belongs to the small heat shock protein (HSP20) family
VC0395_A2504	COG0187	DNA topoisomerase II activity
VC0395_A2505	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VC0395_A2506	COG0592	DNA-directed DNA polymerase activity
VC0395_A2507	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VC0395_A2511	COG1126	abc transporter atp-binding protein
VC0395_A2512	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VC0395_A2513	COG0594	ribonuclease P activity
VC0395_A2514	COG0706	membrane insertase activity
VC0395_A2515	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
VC0395_A2516	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VC0395_A2517	COG0445	tRNA wobble uridine modification
VC0395_A2518	COG0357	Ribosomal RNA small subunit methyltransferase G
VC0395_A2519	COG1192	Involved in chromosome partitioning
VC0395_A2520	COG1475	DNA binding
VC0395_A2521	COG3312	ion transport
VC0395_A2522	COG0356	it plays a direct role in the translocation of protons across the membrane
VC0395_A2524	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VC0395_A2525	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VC0395_A2526	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VC0395_A2527	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VC0395_A2528	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VC0395_A2529	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VC0395_A2530	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VC0395_A2531	COG2814	Major facilitator Superfamily
VC0395_A2532	COG0583	DNA-binding transcription factor activity
VC0395_A2533	COG0183	Belongs to the thiolase family
VC0395_A2534	COG1024	Enoyl-CoA hydratase
VC0395_A2534	COG1250	3-hydroxyacyl-CoA dehydrogenase
VC0395_A2535	COG1739	Uncharacterized protein family UPF0029
VC0395_A2536	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VC0395_A2537	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
VC0395_A2549	COG0583	DNA-binding transcription factor activity
VC0395_A2550	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VC0395_A2551	COG2960	long-chain fatty acid transporting porin activity
VC0395_A2552	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VC0395_A2553	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VC0395_A2554	COG1309	transcriptional regulator
VC0395_A2564	COG0747	negative chemotaxis
VC0395_A2566	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VC0395_A2568	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VC0395_A2569	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VC0395_A2571	COG0210	DNA helicase
VC0395_A2572	COG1280	lysine exporter protein (LysE YggA)
VC0395_A2575	COG2962	Rard protein
VC0395_A2576	COG0514	ATP-dependent DNA helicase (RecQ)
VC0395_A2579	COG1132	(ABC) transporter
VC0395_A2580	COG4774	siderophore transport
VC0395_A2581	COG1120	ATPase activity
VC0395_A2585	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VC0395_A2586	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VC0395_A2586	COG1263	PTS System
VC0395_A2588	COG1561	YicC-like family, N-terminal region
VC0395_A2589	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VC0395_A2590	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VC0395_A2591	COG1560	Kdo2-lipid A biosynthetic process
VC0395_A2592	COG1560	Kdo2-lipid A biosynthetic process
VC0395_A2593	COG1309	transcriptional regulator
VC0395_A2595	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VC0395_A2599	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VC0395_A2600	COG0267	Belongs to the bacterial ribosomal protein bL33 family
VC0395_A2602	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VC0395_A2603	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VC0395_A2604	COG0859	PFAM glycosyl transferase family 9
VC0395_A2605	COG0463	Glycosyl transferase, family 2
VC0395_A2606	COG0859	PFAM glycosyl transferase family 9
VC0395_A2607	COG3642	lipopolysaccharide core region biosynthetic process
VC0395_A2613	COG1519	Transferase
VC0395_A2620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VC0395_A2621	COG0662	Cupin 2, conserved barrel domain protein
VC0395_A2621	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
VC0395_A2622	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VC0395_A2623	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
VC0395_A2629	COG0318	PFAM AMP-dependent synthetase and ligase
VC0395_A2630	COG1454	alcohol dehydrogenase
VC0395_A2630	COG1012	belongs to the aldehyde dehydrogenase family
VC0395_A2634	COG5433	transposase activity
VC0395_A2635	COG5433	transposase activity
VC0395_A2642	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VC0395_A2643	COG0668	transmembrane transport
VC0395_A2644	COG1573	uracil-dna glycosylase
VC0395_A2646	COG3068	Protein conserved in bacteria
VC0395_A2648	COG1940	carbohydrate kinase activity
VC0395_A2649	COG1253	flavin adenine dinucleotide binding
VC0395_A2650	COG0776	regulation of translation
VC0395_A2652	COG0151	Belongs to the GarS family
VC0395_A2653	COG0138	bifunctional purine biosynthesis protein purh
VC0395_A2655	COG0789	Transcriptional regulator
VC0395_A2656	COG3710	Transcriptional regulator
VC0395_A2657	COG0531	amino acid
VC0395_A2658	COG1982	Orn Lys Arg decarboxylase major
VC0395_A2659	COG0840	transmembrane signaling receptor activity
VC0395_A2663	COG0800	Aldolase
VC0395_A2665	COG3265	gluconokinase activity
VC0395_A2666	COG0129	dihydroxy-acid dehydratase activity
VC0395_A2667	COG1609	Transcriptional regulator
VC0395_A2674	COG1857	crispr-associated protein
VC0395_A2676	COG1518	maintenance of DNA repeat elements
VC0395_A2685	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VC0395_A2686	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VC0395_A2687	COG2264	protein methyltransferase activity
VC0395_A2688	COG0439	Biotin carboxylase
VC0395_A2689	COG0511	ligase activity, forming carbon-carbon bonds
VC0395_A2690	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VC0395_A2691	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VC0395_A2694	COG2814	Major facilitator Superfamily
VC0395_A2695	COG2205	protein histidine kinase activity
VC0395_A2695	COG0784	Response regulator, receiver
VC0395_A2696	COG0248	Ppx GppA phosphatase
VC0395_A2697	COG0513	Belongs to the DEAD box helicase family
VC0395_A2698	COG3118	belongs to the thioredoxin family
VC0395_A2699	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
VC0395_A2702	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VC0395_A2714	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VC0395_A2716	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VC0395_A2718	COG1072	(Pantothenic acid kinase))
VC0395_A2723	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VC0395_A2724	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VC0395_A2725	COG0250	Participates in transcription elongation, termination and antitermination
VC0395_A2726	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VC0395_A2727	COG0081	regulation of translation
VC0395_A2728	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VC0395_A2729	COG0222	ribosome binding
VC0395_A2730	COG0085	RNA polymerase activity
VC0395_A2731	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VC0395_A2732	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VC0395_A2733	COG2816	NAD+ diphosphatase activity
VC0395_A2734	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VC0395_A2736	COG4942	peptidase
VC0395_A2738	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VC0395_A2740	COG0471	metal ion transport
VC0395_A2740	COG0490	domain, Protein
VC0395_A2741	COG0688	phosphatidylethanolamine metabolic process
VC0395_A2742	COG1162	GTPase activity
VC0395_A2743	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VC0395_A2753	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VC0395_A2754	COG0802	atpase or kinase
VC0395_A2756	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VC0395_A2757	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VC0395_A2758	COG1923	regulation of RNA biosynthetic process
VC0395_A2759	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VC0395_A2760	COG0330	HflC and HflK could
VC0395_A2761	COG0330	HflC and HflK could
VC0395_A2762	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VC0395_A2763	COG2900	Belongs to the SlyX family
VC0395_A2766	COG0545	Peptidyl-prolyl cis-trans isomerase
VC0395_A2767	COG2964	Protein conserved in bacteria
VC0395_A2768	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VC0395_A2769	COG2923	Belongs to the DsrF TusC family
VC0395_A2771	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
VC0395_A2772	COG0049	tRNA binding
VC0395_A2773	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VC0395_A2774	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VC0395_A2775	COG2906	2 iron, 2 sulfur cluster binding
VC0395_A2777	COG0360	Binds together with S18 to 16S ribosomal RNA
VC0395_A2778	COG2965	DNA replication, synthesis of RNA primer
VC0395_A2779	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
VC0395_A2780	COG0359	binds to the 23S rRNA
VC0395_A2782	COG0305	Participates in initiation and elongation during chromosome replication
VC0395_A2783	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VC0395_A2784	COG0432	Pfam Uncharacterised protein family UPF0047
VC0395_A2785	COG0166	Belongs to the GPI family
VC0395_A2788	COG0735	belongs to the Fur family
VC0395_A2790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VC0395_A2795	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VC0395_A2796	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VC0395_A2797	COG0175	sulfate reduction
VC0395_A2808	COG1410	methionine synthase
VC0395_A2808	COG0646	methionine synthase
VC0395_A2809	COG0527	aspartate kinase activity
VC0395_A2810	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VC0395_A2812	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VC0395_A2815	COG0629	single-stranded DNA binding
VC0395_A2816	COG2199	diguanylate cyclase activity
VC0395_A2816	COG2200	EAL domain
VC0395_A2821	COG3409	Peptidoglycan-binding domain 1 protein
VC0395_A2821	COG3267	Type II secretory pathway component ExeA
VC0395_A2823	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VC0395_A2824	COG1459	type II secretion system
VC0395_A2834	COG1077	Cell shape determining protein MreB Mrl
VC0395_A2835	COG1792	Involved in formation and maintenance of cell shape
VC0395_A2836	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VC0395_A2837	COG0424	maF-like protein
VC0395_A2838	COG1530	ribonuclease E activity
VC0395_A2839	COG3164	Protein of unknown function
VC0395_A2840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VC0395_A2841	COG0312	modulator of DNA gyrase
VC0395_A2842	COG2235	arginine
VC0395_A2846	COG0589	response to stress
VC0395_A2849	COG1438	arginine binding
VC0395_A2850	COG0039	L-malate dehydrogenase activity
VC0395_A2851	COG0531	amino acid
VC0395_A2852	COG0142	geranyltranstransferase activity
VC0395_A2853	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VC0395_A2854	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VC0395_A2855	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VC0395_A2856	COG2966	Psort location CytoplasmicMembrane, score
VC0395_A2857	COG3610	response to peptide
VC0395_A2859	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VC0395_A2860	COG2967	ApaG domain
VC0395_A2861	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VC0395_A2862	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VC0395_A2863	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VC0395_A2864	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VC0395_A2865	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA