locus-tag	class	description
VC395_0003	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
VC395_0004	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
VC395_0005	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
VC395_0010	ENOG4105CAF	HipA N-terminal domain protein
VC395_0021	ENOG4108C33	Resolvase
VC395_0026	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
VC395_0029	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
VC395_0030	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VC395_0031	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
VC395_0032	ENOG4105CAK	Cell division ATP-binding protein ftsE
VC395_0033	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
VC395_0034	ENOG4106H78	methyltransferase
VC395_0041	ENOG4108RMU	ferritin dps family protein
VC395_0043	ENOG4105D58	Diguanylate phosphodiesterase
VC395_0044	ENOG410829K	Lysine exporter protein (Lyse ygga)
VC395_0045	ENOG4108EUD	Lysophospholipase
VC395_0046	ENOG4105DQF	Hydrolase
VC395_0050	ENOG4105BZU	Histidine kinase
VC395_0051	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
VC395_0052	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
VC395_0053	ENOG4105CT0	Protein of unknown function, DUF484
VC395_0054	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
VC395_0055	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
VC395_0057	ENOG4105XQ6	frataxin-like protein
VC395_0058	ENOG4107T0K	Adenylate cyclase
VC395_0060	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
VC395_0061	ENOG41076E6	Uroporphyrinogen-III Synthase
VC395_0062	ENOG4105ECF	c-methyltransferase
VC395_0063	ENOG410601J	HemY protein
VC395_0064	ENOG4105D4P	Coproporphyrinogen iii oxidase
VC395_0065	ENOG4105XCT	Protein of unknown function (DUF2489)
VC395_0066	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
VC395_0068	ENOG4106RE7	Cytochrome
VC395_0069	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
VC395_0072	ENOG4105C2M	dna polymerase I
VC395_0075	ENOG4105D52	delta-aminolevulinic acid dehydratase
VC395_0077	ENOG4105F8V	Hydrolase, tatD family
VC395_0080	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
VC395_0082	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_0083	ENOG4105X6C	Flagellar basal body-associated protein FliL
VC395_0085	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
VC395_0086	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
VC395_0087	ENOG4105E55	glycerol-3-phosphate acyltransferase
VC395_0088	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
VC395_0090	ENOG4107R73	Mate efflux family protein
VC395_0091	ENOG4105CA0	peroxidase
VC395_0092	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
VC395_0093	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
VC395_0094	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
VC395_0095	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
VC395_0096	ENOG4105JC1	sterol-binding domain protein
VC395_0097	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
VC395_0098	ENOG4105CGY	Dna recombination protein
VC395_0100	ENOG4105CBX	hi0933 family
VC395_0101	ENOG4108V6B	universal stress protein B
VC395_0102	ENOG41090A1	ferritin
VC395_0104	ENOG4108M6U	Universal stress protein A
VC395_0105	ENOG4105EMK	carboxylate amino acid amine transporter
VC395_0107	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
VC395_0108	ENOG4105BZU	Histidine kinase
VC395_0109	ENOG4108VVK	transcriptional Regulator, AsnC
VC395_0111	ENOG4105CNH	Multidrug resistance protein MdtL
VC395_0113	ENOG4105DC7	peptidase M24
VC395_0113	ENOG4105DC7	peptidase M24
VC395_0114	ENOG4105D41	biosynthesis protein thiH
VC395_0115	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
VC395_0116	ENOG4105WHD	thiamine biosynthesis protein ThiS
VC395_0117	ENOG4105D06	uba thif-type nad fad binding protein
VC395_0119	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
VC395_0120	ENOG4105WMR	Protein CrcB homolog
VC395_0122	ENOG4108Z0R	Transferase
VC395_0124	ENOG4105E2X	shikimate dehydrogenase
VC395_0125	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
VC395_0126	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
VC395_0128	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
VC395_0129	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
VC395_0130	ENOG4108WI1	Dna topoisomerase
VC395_0131	ENOG4108RPN	Protein smg homolog
VC395_0132	ENOG4105C79	DNA protecting protein DprA
VC395_0133	ENOG4108WZM	domain protein
VC395_0134	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
VC395_0135	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
VC395_0136	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
VC395_0137	ENOG4105C1A	potassium transporter peripheral membrane
VC395_0138	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
VC395_0140	ENOG4108UT2	hemolysin iii
VC395_0141	ENOG4108N23	SpoOM-related protein
VC395_0143	ENOG4105PC1	Conserved Protein
VC395_0145	ENOG4105E27	serine threonine protein kinase
VC395_0146	ENOG4108Z33	Thiol disulfide Interchange Protein
VC395_0147	ENOG4106HNH	Acyl-transferase
VC395_0148	ENOG4105C0P	Mg chelatase subunit ChlI
VC395_0151	ENOG4105CM2	brancheD-chain amino acid aminotransferase
VC395_0152	ENOG4105C01	Dihydroxy-acid dehydratase
VC395_0153	ENOG4105C7B	Threonine dehydratase
VC395_0154	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
VC395_0156	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
VC395_0159	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
VC395_0160	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
VC395_0161	ENOG4105JKW	Valine--pyruvate aminotransferase
VC395_0162	ENOG4108ZNX	Heat shock protein
VC395_0165	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VC395_0166	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
VC395_0167	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
VC395_0168	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
VC395_0170	ENOG4105EAB	amino acid AbC transporter
VC395_0171	ENOG4105E5Q	amino acid AbC transporter
VC395_0174	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
VC395_0175	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
VC395_0176	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
VC395_0177	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
VC395_0178	ENOG4105QTB	Flavodoxin
VC395_0180	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
VC395_0181	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
VC395_0182	ENOG4107QJE	Chromosome Partitioning Protein
VC395_0183	ENOG4105FA0	parb-like partition protein
VC395_0184	ENOG410684E	atp synthase
VC395_0185	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
VC395_0186	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
VC395_0187	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
VC395_0188	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
VC395_0189	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
VC395_0190	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
VC395_0191	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
VC395_0192	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
VC395_0193	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
VC395_0194	ENOG4105CZQ	inner membrane transport protein YdhC
VC395_0195	ENOG4105F52	Transcriptional regulator
VC395_0196	ENOG4105CHU	acetyl-coa acetyltransferase
VC395_0197	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
VC395_0198	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
VC395_0199	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
VC395_0200	ENOG4108RR8	protoporphyrinogen oxidase
VC395_0204	ENOG4105EMY	transcriptional regulator
VC395_0205	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
VC395_0206	ENOG4105W0Z	cytoplasmic protein
VC395_0207	ENOG4105BZS	acriflavin resistance protein
VC395_0208	ENOG410624X	efflux transporter, rnd family, mfp subunit
VC395_0209	ENOG4105Y7M	Transcriptional regulator, TetR family
VC395_0210	ENOG4105C4R	Atp-dependent dna helicase
VC395_0211	ENOG4105MPD	Cytochrome
VC395_0214	ENOG4105DEF	Extracellular solute-binding protein, family 5
VC395_0215	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
VC395_0216	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
VC395_0218	ENOG4105DC8	reductase
VC395_0219	ENOG4105D6S	protein involved in catabolism of external DNA
VC395_0220	ENOG4105DGW	oligopeptidase A
VC395_0222	ENOG4105C4R	Atp-dependent dna helicase
VC395_0224	ENOG4108DMH	HTH_ARAC
VC395_0227	ENOG4105FR1	rard protein
VC395_0228	ENOG4105C9U	ATP-dependent DNA helicase RecQ
VC395_0231	ENOG4105BZ1	(ABC) transporter
VC395_0232	ENOG4105E0K	tonB-dependent siderophore receptor
VC395_0233	ENOG4105E0A	ABC, transporter
VC395_0234	ENOG4105J76	Periplasmic binding protein
VC395_0235	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
VC395_0236	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
VC395_0238	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VC395_0239	ENOG4105C5Y	PTS System
VC395_0241	ENOG4105DSJ	YicC domain protein
VC395_0242	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
VC395_0243	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
VC395_0244	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
VC395_0245	ENOG4105D1S	lipid A biosynthesis
VC395_0246	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
VC395_0247	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
VC395_0248	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_0250	ENOG4105KDC	50s ribosomal protein l28
VC395_0251	ENOG4105W0E	50S ribosomal protein L33
VC395_0253	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
VC395_0254	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
VC395_0255	ENOG4105M5K	heptosyltransferase
VC395_0256	ENOG4106WTF	Glycosyl transferase, family 2
VC395_0257	ENOG4105DKP	glycosyl transferase, family 9
VC395_0259	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
VC395_0265	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
VC395_0266	ENOG4108ST3	glycosyltransferase
VC395_0268	ENOG4105XA0	heptosyltransferase ii
VC395_0271	ENOG4107T94	Endo-14-beta-xylanase
VC395_0272	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
VC395_0273	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
VC395_0274	ENOG4107QKV	phosphomannomutase
VC395_0275	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
VC395_0276	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
VC395_0279	ENOG4105EY8	ABC transporter
VC395_0281	ENOG4105CEY	Amp-dependent synthetase and ligase
VC395_0282	ENOG4108EKI	Dehydrogenase
VC395_0284	ENOG4108UT6	Transferase hexapeptide repeat containing protein
VC395_0292	ENOG4105D3Q	Sugar transferase
VC395_0293	ENOG4105CY0	Metallo-Beta-Lactamase
VC395_0294	ENOG4105CUY	Mechanosensitive ion channel
VC395_0295	ENOG4108RG0	uracil-dna glycosylase
VC395_0296	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
VC395_0297	ENOG4105R2J	Conserved Protein
VC395_0298	ENOG4105EIP	mannose-6-phosphate isomerase
VC395_0299	ENOG4105DKQ	ROK family
VC395_0302	ENOG4105K70	DNA-binding protein
VC395_0304	ENOG4105C12	Phosphoribosylglycinamide synthetase
VC395_0305	ENOG4105DC1	bifunctional purine biosynthesis protein purh
VC395_0306	ENOG4105W1Y	Transcriptional regulator
VC395_0307	ENOG4108M3R	transcriptional activator CadC
VC395_0309	ENOG4105D5Q	Arginine ornithine antiporter
VC395_0310	ENOG4105CXN	decarboxylase
VC395_0311	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_0313	ENOG4105E0K	tonB-dependent siderophore receptor
VC395_0314	ENOG4108UHU	Aldolase
VC395_0315	ENOG4105C6Z	Gluconate
VC395_0316	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
VC395_0317	ENOG4105C01	Dihydroxy-acid dehydratase
VC395_0318	ENOG4105DIQ	Transcriptional regulator
VC395_0320	ENOG4107R3N	Filamentation induced by cAMP protein fic
VC395_0325	ENOG41060M0	Crispr-associated protein, cse4 family
VC395_0327	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
VC395_0334	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
VC395_0335	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
VC395_0337	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
VC395_0339	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
VC395_0340	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
VC395_0341	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
VC395_0342	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
VC395_0346	ENOG4105D8G	Major Facilitator superfamily
VC395_0347	ENOG4105BZU	Histidine kinase
VC395_0348	ENOG4105C9X	ppx gppa phosphatase
VC395_0349	ENOG4105C1J	atp-dependent rna helicase
VC395_0350	ENOG4105K63	Thioredoxin
VC395_0351	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
VC395_0353	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
VC395_0355	ENOG4107QK7	reductase
VC395_0358	ENOG4105JIM	Phosphatidylserine synthase
VC395_0361	ENOG4105D4A	Cell wall formation (By similarity)
VC395_0362	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
VC395_0363	ENOG4105CS9	pantothenic acid kinase
VC395_0364	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
VC395_0365	ENOG4105PM1	preprotein translocase subunit SecE
VC395_0366	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
VC395_0367	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
VC395_0368	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
VC395_0369	ENOG4108VZM	50s ribosomal protein L10
VC395_0370	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
VC395_0371	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VC395_0372	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VC395_0373	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
VC395_0374	ENOG4105E09	nadh pyrophosphatase
VC395_0375	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
VC395_0376	ENOG41062JF	Transcriptional regulator
VC395_0378	ENOG41063SB	peptidase
VC395_0379	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
VC395_0381	ENOG4107QWE	)-transporter
VC395_0382	ENOG4105DJ4	phosphatidylserine decarboxylase
VC395_0383	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
VC395_0384	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
VC395_0385	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
VC395_0386	ENOG4105K8N	protein family UPF0079, ATPase
VC395_0387	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
VC395_0388	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
VC395_0389	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
VC395_0390	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
VC395_0391	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
VC395_0392	ENOG4107QJR	hflk protein
VC395_0393	ENOG4105EPW	hflc protein
VC395_0395	ENOG41069P5	Protein slyX homolog
VC395_0397	ENOG4108V1T	peptidylprolyl cis-trans isomerase
VC395_0398	ENOG4105WWK	YheO domain protein
VC395_0399	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
VC395_0400	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
VC395_0402	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
VC395_0403	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
VC395_0404	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
VC395_0405	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
VC395_0407	ENOG4105W53	bacterioferritin-associated ferredoxin
VC395_0408	ENOG4108UQY	Iron-storage protein
VC395_0409	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
VC395_0410	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
VC395_0411	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
VC395_0412	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
VC395_0414	ENOG4105CDU	Replicative dna helicase
VC395_0415	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
VC395_0416	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
VC395_0417	ENOG4107QP8	phosphohexose isomerase
VC395_0421	ENOG4105MYN	Zinc uptake regulation protein
VC395_0422	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
VC395_0424	ENOG4105P4Z	Phage shock protein G
VC395_0428	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
VC395_0429	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
VC395_0430	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
VC395_0433	ENOG4105EEQ	Na H antiporter
VC395_0434	ENOG4105C3R	Methionine synthase
VC395_0435	ENOG4105CFH	Aspartokinase
VC395_0436	ENOG4105C5R	Aminotransferase
VC395_0438	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
VC395_0439	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
VC395_0440	ENOG41086KC	Transcriptional regulator
VC395_0441	ENOG4108UUM	single-stranded DNA-binding protein
VC395_0442	ENOG41062P1	Diguanylate cyclase phosphodiesterase
VC395_0446	ENOG4105E4G	Type IV pilus
VC395_0449	ENOG4107QHF	type ii secretion system protein e
VC395_0450	ENOG4105D7Q	type ii secretion system
VC395_0459	ENOG4105DFF	Rod shape-determining protein mreb
VC395_0460	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
VC395_0461	ENOG4105VQ7	Rod shape-determining protein MreD
VC395_0462	ENOG4108Z03	MAF-like protein
VC395_0463	ENOG4105C03	ribonuclease
VC395_0464	ENOG4105QD6	exported protein
VC395_0466	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
VC395_0467	ENOG4105CEU	Arginine dihydrolase
VC395_0472	ENOG41081QV	Universal stress protein
VC395_0475	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
VC395_0476	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
VC395_0477	ENOG4105D5Q	Arginine ornithine antiporter
VC395_0478	ENOG4105EAH	synthase
VC395_0479	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
VC395_0480	ENOG4105K46	50S ribosomal protein l27
VC395_0481	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VC395_0482	ENOG4105DWK	Membrane
VC395_0483	ENOG4107XM3	UPF0442 protein
VC395_0485	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
VC395_0486	ENOG4105NWN	ApaG protein
VC395_0487	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
VC395_0488	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
VC395_0489	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
VC395_0490	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
VC395_0491	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
VC395_0494	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
VC395_0495	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
VC395_0496	ENOG4105CEN	a g-specific adenine glycosylase
VC395_0497	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
VC395_0498	ENOG4105CSV	Glutaminase
VC395_0499	ENOG4105CSA	Coproporphyrinogen iii oxidase
VC395_0500	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
VC395_0502	ENOG4105VZ9	UPF0235 protein
VC395_0503	ENOG4108VIA	integral membrane protein
VC395_0504	ENOG4105II7	pyrroline-5-carboxylate reductase
VC395_0505	ENOG4105DFA	alanine racemase domain protein
VC395_0506	ENOG4105CZX	twitching motility protein
VC395_0507	ENOG4105CZX	twitching motility protein
VC395_0509	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
VC395_0510	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
VC395_0511	ENOG4108UJU	UPF0301 protein
VC395_0512	ENOG4105D7Z	glutathione synthase
VC395_0513	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
VC395_0514	ENOG4105RWS	endonuclease I
VC395_0515	ENOG4105GPY	SprT protein
VC395_0516	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
VC395_0517	ENOG4105CV1	Transketolase (EC 2.2.1.1)
VC395_0518	ENOG4108R4R	Iron-regulated virulence regulatory protein
VC395_0519	ENOG4105D05	Receptor
VC395_0520	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
VC395_0521	ENOG4105BZA	Phosphoglycerate kinase
VC395_0522	ENOG4105D2N	Aldolase
VC395_0524	ENOG4105D64	Mechanosensitive ion channel
VC395_0525	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
VC395_0526	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
VC395_0527	ENOG4105MPN	Membrane
VC395_0529	ENOG4105CA9	Pyruvate kinase
VC395_0530	ENOG410804X	Transcriptional regulator
VC395_0531	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
VC395_0532	ENOG4105CH5	extracellular solute-binding protein, family 7
VC395_0534	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VC395_0535	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
VC395_0536	ENOG4105KTH	gatB Yqey
VC395_0537	ENOG4105VCC	30S ribosomal protein S21
VC395_0538	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
VC395_0540	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
VC395_0541	ENOG4107ZVW	dihydroneopterin aldolase
VC395_0542	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VC395_0543	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
VC395_0545	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
VC395_0546	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
VC395_0547	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
VC395_0548	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
VC395_0549	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
VC395_0550	ENOG4108K5P	(LipO)protein
VC395_0551	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VC395_0552	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
VC395_0554	ENOG4105C6T	cysteine synthase
VC395_0555	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
VC395_0556	ENOG4108I5D	sulfate abc transporter
VC395_0557	ENOG4105ECW	sulfate abc transporter
VC395_0558	ENOG4108IJ6	ABC transporter
VC395_0560	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
VC395_0561	ENOG4105Y3E	Modulates RecA activity (By similarity)
VC395_0562	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
VC395_0564	ENOG4105CFH	Aspartokinase
VC395_0565	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
VC395_0567	ENOG4107QSA	Oxaloacetate decarboxylase
VC395_0568	ENOG4105D9Q	decarboxylase (Beta subunit)
VC395_0570	ENOG4105W39	Membrane
VC395_0573	ENOG4105D9M	gamma-glutamylcysteine synthetase
VC395_0574	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
VC395_0575	ENOG4108JU6	CBS domain protein
VC395_0576	ENOG4106KVJ	cytochrome C assembly protein
VC395_0577	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VC395_0578	ENOG4105K5M	30s ribosomal protein S16
VC395_0579	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
VC395_0580	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
VC395_0581	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
VC395_0582	ENOG4105C0H	protease
VC395_0583	ENOG4105C0H	protease
VC395_0585	ENOG4105D6Z	AFG1 family ATPase
VC395_0587	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
VC395_0588	ENOG4108UJD	30S ribosomal protein S9
VC395_0590	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
VC395_0591	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
VC395_0592	ENOG4105EIX	cytochrome c1
VC395_0593	ENOG4107MKT	Stringent starvation protein a
VC395_0594	ENOG4105KB2	stringent starvation protein b
VC395_0595	ENOG4105W4M	Transport-associated protein
VC395_0596	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
VC395_0597	ENOG41082RQ	UPF0102 protein
VC395_0598	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
VC395_0599	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
VC395_0600	ENOG410630P	Transcriptional regulator
VC395_0602	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
VC395_0603	ENOG41077A9	carbonic anhydrase
VC395_0604	ENOG4105CHH	sulfate transporter
VC395_0606	ENOG4105DA5	(ABC) transporter
VC395_0607	ENOG4105E3A	(ABC) transporter
VC395_0608	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
VC395_0609	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
VC395_0610	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VC395_0611	ENOG4105DJ0	Poly(A) Polymerase
VC395_0612	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
VC395_0613	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VC395_0614	ENOG4105PW4	Sugar fermentation stimulation protein homolog
VC395_0618	ENOG4105CQ7	ATP-dependent helicase
VC395_0619	ENOG4105BZ4	penicillin-binding protein
VC395_0620	ENOG4105D78	K07001 NTE family protein
VC395_0621	ENOG4107QIJ	Aconitate hydratase 2
VC395_0622	ENOG4105XTV	UPF0231 protein
VC395_0623	ENOG4108YZA	Nitrogen regulatory protein pii
VC395_0627	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VC395_0628	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
VC395_0629	ENOG4105E2V	Glycosyltransferase 36
VC395_0630	ENOG4105E2D	ec 3.2.1.52
VC395_0631	ENOG4105RD7	BadF BadG BcrA BcrD
VC395_0633	ENOG4108JQ7	(ABC) transporter
VC395_0634	ENOG4105C3U	ABC transporter
VC395_0635	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
VC395_0637	ENOG4107QRA	Extracellular solute-binding protein, family 5
VC395_0639	ENOG4105BZU	Histidine kinase
VC395_0640	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
VC395_0641	ENOG4105IPI	Membrane
VC395_0643	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
VC395_0644	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
VC395_0647	ENOG4105DR5	peptidase
VC395_0648	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
VC395_0649	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
VC395_0651	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
VC395_0652	ENOG4105HBR	Rna-binding protein
VC395_0653	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
VC395_0654	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
VC395_0655	ENOG4105EEI	dihydropteroate synthase
VC395_0656	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
VC395_0658	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
VC395_0659	ENOG4105CHV	Transcription elongation factor NusA
VC395_0660	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
VC395_0661	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
VC395_0662	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
VC395_0663	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
VC395_0664	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
VC395_0665	ENOG4105RT1	May be involved in cell division (By similarity)
VC395_0668	ENOG4106RZ4	Peptidase U32
VC395_0669	ENOG4105CFP	Peptidase U32
VC395_0670	ENOG4105BZU	Histidine kinase
VC395_0671	ENOG4105XPQ	lipid carrier protein
VC395_0672	ENOG4108YYD	acetyltransferase
VC395_0675	ENOG4105BZU	Histidine kinase
VC395_0676	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
VC395_0677	ENOG4105C1J	atp-dependent rna helicase
VC395_0678	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
VC395_0679	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
VC395_0680	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
VC395_0681	ENOG4105CRK	lysyL-tRNA synthetase
VC395_0682	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VC395_0684	ENOG4105CPC	Aldo Keto reductase
VC395_0685	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
VC395_0688	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
VC395_0689	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
VC395_0690	ENOG4105HF0	Membrane
VC395_0691	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
VC395_0692	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
VC395_0694	ENOG41063Z6	transcriptional regulator, lysR family
VC395_0695	ENOG41080HT	Transcriptional regulator, arsr family
VC395_0696	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
VC395_0697	ENOG4105CJR	Integral membrane protein (MviN
VC395_0698	ENOG4105DTN	riboflavin biosynthesis protein ribF
VC395_0699	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
VC395_0700	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
VC395_0701	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
VC395_0702	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
VC395_0707	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VC395_0708	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
VC395_0709	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
VC395_0710	ENOG4108NEV	two component transcriptional regulator, LytTR family
VC395_0711	ENOG4108HRK	Histidine kinase
VC395_0712	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
VC395_0715	ENOG4105C5H	ABC transporter
VC395_0717	ENOG4107SC1	transglycosylase
VC395_0718	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
VC395_0719	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
VC395_0720	ENOG4108K0B	C-di-gmp phosphodiesterase
VC395_0721	ENOG4107XW0	Spermidine putrescine ABC transporter periplasmic spermidine putrescine-binding protein
VC395_0723	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
VC395_0725	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VC395_0726	ENOG4105C34	Pseudouridine synthase
VC395_0727	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
VC395_0728	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
VC395_0733	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
VC395_0734	ENOG4105CFP	Peptidase U32
VC395_0735	ENOG4105DH7	May be involved in recombination (By similarity)
VC395_0736	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
VC395_0737	ENOG4105BZU	Histidine kinase
VC395_0739	ENOG4105C9X	ppx gppa phosphatase
VC395_0740	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
VC395_0741	ENOG4105C8U	phosphate abc transporter
VC395_0742	ENOG4105E2Z	phosphate ABC transporter (Permease
VC395_0743	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
VC395_0745	ENOG4105CSR	polyphosphate kinase 2
VC395_0747	ENOG4106N3A	copper homeostasis protein cutc
VC395_0748	ENOG4105D3R	alkyl hydroperoxide reductase
VC395_0749	ENOG4105C5Q	Transcriptional regulator
VC395_0751	ENOG4107QP3	malate synthase g
VC395_0753	ENOG4108I9X	Isocitrate lyase
VC395_0754	ENOG4105W87	Cbs domain
VC395_0756	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
VC395_0758	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
VC395_0759	ENOG4105VIE	preprotein translocase, subunit YajC
VC395_0760	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
VC395_0761	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
VC395_0762	ENOG4105ECY	inositol monophosphatase
VC395_0763	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
VC395_0764	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
VC395_0765	ENOG4105C3J	Cysteine desulfurase
VC395_0766	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
VC395_0767	ENOG4108Z4V	iron-sulfur cluster assembly
VC395_0768	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
VC395_0769	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
VC395_0770	ENOG4108ZIT	Ferredoxin, 2FE-2S
VC395_0771	ENOG4105WVQ	Fe-S assembly protein IscX
VC395_0772	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
VC395_0773	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
VC395_0774	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
VC395_0776	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
VC395_0777	ENOG4105CUT	histidyl-tRNA synthetase
VC395_0778	ENOG4105N21	Membrane
VC395_0779	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
VC395_0780	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
VC395_0783	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
VC395_0784	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
VC395_0785	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
VC395_0787	ENOG4106HK8	GPR1 FUN34 yaaH family protein
VC395_0788	ENOG4105WQI	isochorismatase
VC395_0789	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
VC395_0790	ENOG4105E4F	Isochorismate synthase
VC395_0791	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
VC395_0793	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
VC395_0794	ENOG4105DQ5	transport system permease protein
VC395_0795	ENOG4105TVJ	transport system, permease
VC395_0796	ENOG4105E0A	ABC, transporter
VC395_0798	ENOG41064T2	transcriptional regulator, lysR family
VC395_0800	ENOG4105EUZ	Beta-lactamase domain protein
VC395_0801	ENOG4105BZG	amino acid carrier protein
VC395_0803	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
VC395_0807	ENOG4106YYS	transcriptional regulatory protein
VC395_0808	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
VC395_0809	ENOG4105D9Q	decarboxylase (Beta subunit)
VC395_0810	ENOG4107QSA	Oxaloacetate decarboxylase
VC395_0813	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
VC395_0814	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
VC395_0815	ENOG4105CI0	Citrate lyase
VC395_0816	ENOG4105CHY	citrate lyase, alpha
VC395_0817	ENOG4105YGP	holo-ACP synthase CitX
VC395_0818	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
VC395_0821	ENOG4108Z4U	Ferredoxin
VC395_0823	ENOG4105DZ0	fad dependent oxidoreductase
VC395_0836	ENOG4105C26	Dehydrogenase
VC395_0840	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
VC395_0844	ENOG4105XB6	Toxin coregulated pilin
VC395_0847	ENOG4105GRU	toxin co-regulated pilus biosynthesis outer membrane protein C
VC395_0851	ENOG4107QHF	type ii secretion system protein e
VC395_0852	ENOG4108VEY	type ii secretion system
VC395_0855	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
VC395_0856	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_0859	ENOG4105DR5	peptidase
VC395_0861	ENOG4105F88	accessory colonization factor AcfD
VC395_0863	ENOG4105DFP	Integrase
VC395_0864	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
VC395_0865	ENOG4108Z1B	Cyclase dehydrase
VC395_0866	ENOG4105VDB	UPF0125 protein
VC395_0867	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
VC395_0868	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
VC395_0869	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
VC395_0870	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VC395_0871	ENOG4105CFG	Acts as a chaperone (By similarity)
VC395_0872	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
VC395_0874	ENOG4106855	Competence protein
VC395_0879	ENOG4105CFC	Transporter
VC395_0880	ENOG4108Z6B	deaminase
VC395_0882	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
VC395_0885	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
VC395_0886	ENOG4108RS6	transposase
VC395_0891	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
VC395_0892	ENOG4108R96	Methyltransferase, YaeB family
VC395_0894	ENOG4105NRA	50s ribosomal protein l31 type b
VC395_0896	ENOG4105CFC	Transporter
VC395_0897	ENOG4108UPT	UPF0178 protein
VC395_0900	ENOG4108428	Inherit from COG: -acetyltransferase
VC395_0903	ENOG4105WP7	tRNA pseudouridine synthase C
VC395_0904	ENOG4105DR9	pseudouridine synthase
VC395_0905	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
VC395_0906	ENOG4105CTB	Polyprenyl synthetase
VC395_0908	ENOG4105E14	MotA TolQ exbB proton channel
VC395_0909	ENOG4106VK6	Flagellar motor protein
VC395_0910	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
VC395_0912	ENOG4105ETT	transcriptional Regulator, LysR family
VC395_0913	ENOG4105M08	Membrane
VC395_0914	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
VC395_0915	ENOG4105EWT	decarboxylase family
VC395_0916	ENOG4105BZU	Histidine kinase
VC395_0918	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
VC395_0919	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
VC395_0920	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
VC395_0921	ENOG4105D01	(LipO)protein
VC395_0922	ENOG4108UMI	ABC transporter, permease
VC395_0923	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
VC395_0924	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
VC395_0925	ENOG4105D4X	repressor
VC395_0926	ENOG4105C5Y	PTS System
VC395_0927	ENOG4105CG3	alpha amylase, catalytic region
VC395_0930	ENOG4105BZS	acriflavin resistance protein
VC395_0932	ENOG4107ZF2	Phosphatase
VC395_0933	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
VC395_0935	ENOG4108UW5	maltose o-acetyltransferase
VC395_0939	ENOG4105D7W	serine acetyltransferase
VC395_0941	ENOG4105Q84	sucrose synthase
VC395_0943	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
VC395_0946	ENOG4108MA4	Peptidase M66
VC395_0949	ENOG4105D3Q	Sugar transferase
VC395_0951	ENOG4105DAY	polysaccharide export protein
VC395_0952	ENOG4105D75	Capsular exopolysaccharide family
VC395_0956	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
VC395_0958	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
VC395_0959	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
VC395_0960	ENOG4108Z43	UPF0250 protein
VC395_0962	ENOG4105DZ1	carboxypeptidase
VC395_0963	ENOG4105K6T	rare lipoprotein A
VC395_0964	ENOG4105CNI	cell division protein FtsW
VC395_0965	ENOG4105CJN	penicillin-binding protein
VC395_0966	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
VC395_0967	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
VC395_0968	ENOG4105DJF	DNA polymerase III, delta' subunit
VC395_0969	ENOG4108U2H	Rare lipoprotein B
VC395_0971	ENOG4105C8T	Leucyl-tRNA synthetase
VC395_0972	ENOG4107PAI	alpha helical protein
VC395_0973	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
VC395_0974	ENOG4108JU5	Magnesium and cobalt efflux protein
VC395_0975	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
VC395_0976	ENOG4105C9A	Phoh family
VC395_0977	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
VC395_0978	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
VC395_0979	ENOG4105C5Y	PTS System
VC395_0981	ENOG4105KZ7	phosphocarrier protein hpr
VC395_0983	ENOG4105C6T	cysteine synthase
VC395_0984	ENOG4105EXN	Sulfate transport protein CysZ
VC395_0985	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
VC395_0986	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
VC395_0987	ENOG41081QG	Porin Gram-negative type
VC395_0989	ENOG4108Z6Z	Transcriptional regulator
VC395_0990	ENOG4105G5H	Membrane
VC395_0991	ENOG4107QX8	SPFH domain, Band 7 family protein
VC395_0992	ENOG4107QR8	Thioredoxin
VC395_0994	ENOG4105E1F	short-chain dehydrogenase reductase
VC395_0995	ENOG4105ECP	epimerase
VC395_0996	ENOG4108RE9	Phosphodiesterase
VC395_0999	ENOG4108TU9	TRANSCRIPTIONal
VC395_1000	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
VC395_1001	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
VC395_1002	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
VC395_1003	ENOG4105DUX	Transporter
VC395_1005	ENOG4105MDZ	Transcriptional activator rfaH
VC395_1006	ENOG4105CAQ	asparagine synthetase
VC395_1007	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
VC395_1008	ENOG4105E2R	ROK family
VC395_1009	ENOG4105CE4	GlcNAc 6-P deacetylase
VC395_1010	ENOG4105CI1	PTS System
VC395_1012	ENOG4105CX6	glutaminyL-tRNA synthetase
VC395_1014	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
VC395_1015	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
VC395_1016	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
VC395_1017	ENOG4108S3P	Sporulation domain protein
VC395_1018	ENOG4105E96	Colicin v production protein
VC395_1019	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
VC395_1020	ENOG4105D3Y	Na H antiporter
VC395_1021	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
VC395_1023	ENOG4105EIY	sodium-type flagellar protein motY
VC395_1024	ENOG4106WH9	Protein of unknown function (DUF2753)
VC395_1025	ENOG4108UYE	Lactoylglutathione lyase
VC395_1026	ENOG4105CSM	endonuclease III
VC395_1027	ENOG4105DZB	Electron transport complex
VC395_1028	ENOG4108UQQ	Electron transport complex
VC395_1029	ENOG4105D6A	Electron transport complex
VC395_1031	ENOG4108R3D	Electron transport complex
VC395_1033	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
VC395_1035	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VC395_1037	ENOG4105CHW	UPF0052 protein
VC395_1038	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
VC395_1039	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
VC395_1040	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
VC395_1041	ENOG4105M00	molybdopterin converting factor, subunit 1
VC395_1042	ENOG4108ZAF	Molybdopterin
VC395_1043	ENOG4105BZU	Histidine kinase
VC395_1048	ENOG4108I5U	Uridine phosphorylase
VC395_1050	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
VC395_1051	ENOG4105D1F	ATP-binding protein
VC395_1052	ENOG4105DBI	uridine monophosphokinase
VC395_1053	ENOG4108GAE	asmA family
VC395_1054	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
VC395_1056	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
VC395_1057	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
VC395_1060	ENOG4105CHU	acetyl-coa acetyltransferase
VC395_1061	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
VC395_1062	ENOG41069NU	Nitroreductase
VC395_1063	ENOG4105EJC	lysr family transcriptional regulator
VC395_1064	ENOG4105I93	response regulator
VC395_1066	ENOG4105WD1	Membrane
VC395_1067	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
VC395_1068	ENOG4107QMP	dna polymerase iii subunits gamma and tau
VC395_1069	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
VC395_1070	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
VC395_1071	ENOG4105KRS	Proteinase inhibitor
VC395_1073	ENOG4105UBK	short-chain dehydrogenase reductase
VC395_1074	ENOG4105ERU	peptidase
VC395_1076	ENOG4108XM1	transcriptional regulator AsnC family
VC395_1077	ENOG4105C29	acyl-CoA thioesterase
VC395_1081	ENOG4105BZU	Histidine kinase
VC395_1083	ENOG41082YX	Transcriptional regulator, arsr family
VC395_1084	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
VC395_1090	ENOG4108V1U	phospholipid-binding protein
VC395_1094	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
VC395_1097	ENOG4107YTP	response regulator receiver protein
VC395_1099	ENOG4105BZU	Histidine kinase
VC395_1100	ENOG4105BZU	Histidine kinase
VC395_1101	ENOG4105BZU	Histidine kinase
VC395_1102	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VC395_1106	ENOG4107QSI	ABC, transporter
VC395_1107	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
VC395_1108	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
VC395_1109	ENOG4105C3U	ABC transporter
VC395_1110	ENOG4108JQ7	(ABC) transporter
VC395_1111	ENOG4105CHF	Glutathione S-transferase
VC395_1112	ENOG4108DNC	Involved in acetate metabolism (By similarity)
VC395_1113	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
VC395_1114	ENOG4105PQ6	UPF0208 membrane protein
VC395_1115	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
VC395_1117	ENOG4105C7J	ABC transporter, permease
VC395_1118	ENOG4108JJB	ABC transporter
VC395_1119	ENOG4105BZU	Histidine kinase
VC395_1121	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
VC395_1123	ENOG4105D1H	recombination factor protein RarA
VC395_1125	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
VC395_1126	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
VC395_1127	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
VC395_1128	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
VC395_1129	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
VC395_1130	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
VC395_1132	ENOG4105D0M	Protease HtpX homolog
VC395_1134	ENOG4107FW0	short-chain dehydrogenase reductase
VC395_1137	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
VC395_1139	ENOG4105RHG	
VC395_1141	ENOG4107QTF	adenylosuccinate lyase
VC395_1142	ENOG41075W9	High frequency lysogenization protein HflD homolog
VC395_1143	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
VC395_1144	ENOG4107RE1	Inosine-guanosine kinase
VC395_1146	ENOG4105R8V	Transcriptional regulator
VC395_1147	ENOG4106YXT	transposase
VC395_1148	ENOG4108WTW	DNA transposition protein
VC395_1158	ENOG41065S5	
VC395_1169	ENOG4108Z6H	mu-like prophage Flumu protein gp27
VC395_1170	ENOG4105CF2	Mu-like prophage FluMu protein GP28
VC395_1171	ENOG4105QIB	mu-like prophage Flumu protein gp29
VC395_1179	ENOG4105EFV	Major head subunit
VC395_1181	ENOG4105Y5J	prophage protein
VC395_1185	ENOG4105TKZ	Tail Sheath
VC395_1187	ENOG41062PQ	Mu-like prophage FluMu protein gp41
VC395_1191	ENOG4105PZ7	Baseplate assembly protein
VC395_1193	ENOG4108T86	baseplate J family protein
VC395_1194	ENOG41061A0	Mu-like prophage Flumu protein
VC395_1198	ENOG4107S6Z	Na H antiporter
VC395_1199	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
VC395_1200	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
VC395_1201	ENOG4105CIH	Imidazole acetol-phosphate transaminase
VC395_1202	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
VC395_1203	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
VC395_1204	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
VC395_1205	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
VC395_1206	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
VC395_1207	ENOG4108R99	pseudouridine synthase
VC395_1209	ENOG4105VEQ	Cold shock protein
VC395_1210	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
VC395_1211	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
VC395_1213	ENOG41090BQ	Glutaredoxin
VC395_1214	ENOG4108EKI	Dehydrogenase
VC395_1215	ENOG4106KNT	transcriptional regulator
VC395_1216	ENOG4105DY8	decarboxylase
VC395_1218	ENOG4105DWU	Membrane
VC395_1223	ENOG4105CUX	Signal transduction histidine kinase
VC395_1225	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
VC395_1228	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VC395_1229	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
VC395_1230	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
VC395_1231	ENOG41081XQ	Conserved Protein
VC395_1232	ENOG4105C9M	aspartyl-trna synthetase
VC395_1233	ENOG4107104	thymidine kinase
VC395_1237	ENOG41061A0	Mu-like prophage Flumu protein
VC395_1238	ENOG4108T86	baseplate J family protein
VC395_1240	ENOG4105PZ7	Baseplate assembly protein
VC395_1244	ENOG41062PQ	Mu-like prophage FluMu protein gp41
VC395_1246	ENOG4105TKZ	Tail Sheath
VC395_1250	ENOG4105Y5J	prophage protein
VC395_1252	ENOG4105EFV	Major head subunit
VC395_1260	ENOG4105QIB	mu-like prophage Flumu protein gp29
VC395_1261	ENOG4105CF2	Mu-like prophage FluMu protein GP28
VC395_1262	ENOG4108Z6H	mu-like prophage Flumu protein gp27
VC395_1273	ENOG41065S5	
VC395_1283	ENOG4108WTW	DNA transposition protein
VC395_1284	ENOG4106YXT	transposase
VC395_1285	ENOG4105R8V	Transcriptional regulator
VC395_1288	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
VC395_1289	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
VC395_1290	ENOG4105DK0	Indole-3-glycerol phosphate synthase
VC395_1291	ENOG4108I0Q	anthranilate phosphoribosyltransferase
VC395_1292	ENOG4105DDQ	anthranilate synthase
VC395_1293	ENOG4105CRQ	synthase (Component I)
VC395_1296	ENOG4105DB7	PHP domain protein
VC395_1297	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
VC395_1298	ENOG4105FE9	pseudouridine synthase
VC395_1299	ENOG4108JJ8	(ABC) transporter
VC395_1300	ENOG4108JJ9	ABC, transporter
VC395_1301	ENOG4105C3M	thioredoxin reductase
VC395_1303	ENOG4105C9B	Cysteine desulfurase
VC395_1304	ENOG4105BZU	Histidine kinase
VC395_1305	ENOG4107GZ4	SanA protein
VC395_1307	ENOG4107R1I	NAD-dependent malic enzyme
VC395_1309	ENOG4105C8V	SAICAR synthetase
VC395_1314	ENOG4108ZG0	Ompa motb domain protein
VC395_1317	ENOG4105CQB	FAD linked oxidase domain protein
VC395_1319	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
VC395_1321	ENOG4105C84	Histidine ammonia-lyase
VC395_1322	ENOG4105CGP	Urocanate hydratase
VC395_1323	ENOG41088SP	formiminoglutamate hydrolase
VC395_1324	ENOG4105CI2	imidazolone-5-propionate hydrolase
VC395_1325	ENOG4105CZE	histidine utilization repressor
VC395_1328	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
VC395_1330	ENOG4105BZU	Histidine kinase
VC395_1331	ENOG4105CQ2	DNA polymerase
VC395_1332	ENOG4105WH1	Two component transcriptional regulator luxr family
VC395_1333	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
VC395_1335	ENOG4105BZU	Histidine kinase
VC395_1338	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
VC395_1339	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
VC395_1341	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
VC395_1345	ENOG4105FQ6	thiopurine methyltransferase
VC395_1350	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
VC395_1351	ENOG41067MG	lrgb family
VC395_1353	ENOG4105CJB	Exodeoxyribonuclease I
VC395_1354	ENOG4108ETY	sodium dicarboxylate symporter
VC395_1355	ENOG4105E0X	reductase
VC395_1356	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
VC395_1357	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
VC395_1358	ENOG4108YZT	Adenosylcobinamide kinase
VC395_1363	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
VC395_1364	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
VC395_1367	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_1373	ENOG4107QK7	reductase
VC395_1374	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
VC395_1375	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
VC395_1376	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
VC395_1377	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VC395_1378	ENOG4105C72	UPF0176 protein
VC395_1380	ENOG4105S8Q	sugar efflux transporter
VC395_1382	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
VC395_1388	ENOG4105EAQ	(twin-arginine translocation) pathway signal
VC395_1389	ENOG4105C5X	domain protein
VC395_1392	ENOG4105CH5	extracellular solute-binding protein, family 7
VC395_1394	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
VC395_1397	ENOG41067TZ	transcriptional regulator, MarR family
VC395_1398	ENOG4105C94	Transporter
VC395_1400	ENOG4105VZJ	PTS System
VC395_1402	ENOG4105VCP	PTS System
VC395_1403	ENOG4105F8D	glycoside hydrolase family 4
VC395_1404	ENOG410901P	UPF0249 protein
VC395_1405	ENOG41060NJ	transcriptional regulator
VC395_1406	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
VC395_1407	ENOG4105DJ9	glucan biosynthesis protein
VC395_1408	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_1412	ENOG4105CGF	Aromatic amino acid aminotransferase
VC395_1414	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
VC395_1415	ENOG4105DWF	phosphomethylpyrimidine kinase
VC395_1416	ENOG4105C5S	asparaginyl-tRNA synthetase
VC395_1417	ENOG4108NVR	Methyl-accepting chemotaxis
VC395_1418	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
VC395_1419	ENOG4105EJQ	L-serine dehydratase
VC395_1420	ENOG4105C44	Serine transporter
VC395_1421	ENOG4105P8F	nudix hydrolase
VC395_1422	ENOG4105CRQ	synthase (Component I)
VC395_1425	ENOG4105CM6	amino acid regulated cytosolic protein
VC395_1427	ENOG4108JU8	Transcriptional regulator
VC395_1428	ENOG4105D9U	N-acetyltransferase
VC395_1431	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
VC395_1432	ENOG4108NVR	Methyl-accepting chemotaxis
VC395_1433	ENOG4105C8P	)-transporter
VC395_1434	ENOG4105BZU	Histidine kinase
VC395_1435	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VC395_1436	ENOG4108MJ5	VirK protein
VC395_1437	ENOG4105RW8	MltA-interacting MipA family protein
VC395_1438	ENOG4105EB3	Histidine kinase
VC395_1439	ENOG4107EXC	regulatoR
VC395_1446	ENOG4105C2J	ABC transporter
VC395_1447	ENOG4107SDZ	Galactoside transport system permease protein mglC
VC395_1454	ENOG41073TP	transcriptional regulator
VC395_1455	ENOG4105CR4	methylisocitrate lyase
VC395_1456	ENOG4105BZN	citrate synthase
VC395_1457	ENOG4108I0Z	Aconitate hydratase
VC395_1458	ENOG4105C7F	AcnD-accessory protein PrpF
VC395_1459	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
VC395_1462	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
VC395_1463	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
VC395_1464	ENOG4105F1J	Homogentisate 1,2-dioxygenase
VC395_1466	ENOG4108RXX	maleylacetoacetate isomerase
VC395_1467	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
VC395_1468	ENOG4105BZU	Histidine kinase
VC395_1472	ENOG4106TD9	Diguanylate cyclase
VC395_1473	ENOG4105DR4	Methyltransferase
VC395_1475	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
VC395_1477	ENOG4108MN8	Membrane
VC395_1478	ENOG4105CDA	abc transporter atp-binding protein
VC395_1479	ENOG4105DRP	amino acid AbC transporter
VC395_1480	ENOG4105EZ7	amino acid ABC transporter
VC395_1481	ENOG4107QXX	ABC transporter
VC395_1483	ENOG410667J	hydrolase
VC395_1484	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
VC395_1485	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
VC395_1489	ENOG4105BZU	Histidine kinase
VC395_1491	ENOG4105BZU	Histidine kinase
VC395_1492	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
VC395_1495	ENOG4105BZU	Histidine kinase
VC395_1501	ENOG4105CQ7	ATP-dependent helicase
VC395_1505	ENOG4105R8A	Heat shock protein
VC395_1507	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
VC395_1509	ENOG4105EJC	lysr family transcriptional regulator
VC395_1510	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
VC395_1511	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
VC395_1512	ENOG4105KPY	Small multidrug resistance protein
VC395_1513	ENOG4108NVR	Methyl-accepting chemotaxis
VC395_1514	ENOG4108VYJ	response regulator receiver protein
VC395_1516	ENOG4105CBS	Chea signal transduction histidine kinase
VC395_1517	ENOG4105CBS	Chea signal transduction histidine kinase
VC395_1518	ENOG4105BZU	Histidine kinase
VC395_1520	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
VC395_1521	ENOG4108V3W	Chemotaxis protein, CheW
VC395_1522	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_1524	ENOG4108N3W	hemolysin secretion protein
VC395_1525	ENOG4107SDU	Methyl-accepting chemotaxis
VC395_1526	ENOG4105C1J	atp-dependent rna helicase
VC395_1528	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
VC395_1529	ENOG4105CW7	secretion protein, HlyD family
VC395_1530	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
VC395_1532	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_1533	ENOG4105CTD	carboxy-peptidase
VC395_1534	ENOG4108WC9	type VI secretion system effector, hcp1 family
VC395_1540	ENOG410829K	Lysine exporter protein (Lyse ygga)
VC395_1541	ENOG4105BZG	amino acid carrier protein
VC395_1544	ENOG4107RUE	extracellular solute-binding protein family 1
VC395_1545	ENOG4107RUE	extracellular solute-binding protein family 1
VC395_1546	ENOG4105D38	putrescine abc transporter
VC395_1547	ENOG4105F38	ABC transporter, permease
VC395_1548	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VC395_1552	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
VC395_1553	ENOG4105Q9Y	Universal stress protein
VC395_1554	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
VC395_1557	ENOG4105C59	p-type ATPase
VC395_1559	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
VC395_1562	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
VC395_1565	ENOG4105BZU	Histidine kinase
VC395_1571	ENOG4107927	Cholera enterotoxin, A subunit
VC395_1572	ENOG4105MQ5	zona occludens toxin
VC395_1578	ENOG41067QW	Transcriptional regulator
VC395_1581	ENOG41067QW	Transcriptional regulator
VC395_1601	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
VC395_1602	ENOG4105DAN	ATP-dependent protease
VC395_1603	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
VC395_1606	ENOG4105C5H	ABC transporter
VC395_1608	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
VC395_1610	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
VC395_1611	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
VC395_1614	ENOG4105CD8	aminopeptidase N
VC395_1616	ENOG4105CN1	protease
VC395_1617	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
VC395_1618	ENOG4108ZGC	gaf domain protein
VC395_1619	ENOG4105BZ1	(ABC) transporter
VC395_1620	ENOG4105H2K	paraquat-inducible protein a
VC395_1621	ENOG4105DY2	Paraquat-inducible protein b
VC395_1622	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
VC395_1623	ENOG4105QNR	S1 RNA binding domain protein
VC395_1626	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
VC395_1628	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
VC395_1631	ENOG4105QAX	Iron-sulfur
VC395_1632	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
VC395_1634	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
VC395_1638	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
VC395_1639	ENOG4105C5H	ABC transporter
VC395_1640	ENOG4105BZU	Histidine kinase
VC395_1641	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VC395_1643	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
VC395_1644	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VC395_1645	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
VC395_1646	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
VC395_1650	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
VC395_1651	ENOG4106IUH	DTW domain containing protein
VC395_1653	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_1654	ENOG4107TT5	NLP P60 protein
VC395_1656	ENOG4105FGM	Fructosamine kinase
VC395_1657	ENOG4107QI1	Mate efflux family protein
VC395_1661	ENOG41067XB	TonB family
VC395_1662	ENOG4109015	Biopolymer transport protein exbD tolR
VC395_1667	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
VC395_1668	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
VC395_1669	ENOG4108IJ9	(ABC) transporter
VC395_1670	ENOG4105E98	transcriptional regulator DeoR family
VC395_1671	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
VC395_1672	ENOG4105XEP	YhcH YjgK YiaL family protein
VC395_1673	ENOG4105M4H	endoribonuclease L-psp
VC395_1674	ENOG4105DDV	Transcriptional regulator (LacI family
VC395_1675	ENOG4105CS2	ec 3.2.1.21
VC395_1677	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
VC395_1680	ENOG4107QZV	Type I secretion membrane fusion protein
VC395_1682	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
VC395_1683	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
VC395_1684	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
VC395_1686	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
VC395_1687	ENOG4105C4M	(Ubiquinol oxidase) subunit I
VC395_1689	ENOG4105C9Q	fumarate hydratase class II
VC395_1692	ENOG4105V0I	UPF0267 protein
VC395_1695	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
VC395_1696	ENOG4105DUM	transcriptional regulator, lysR family
VC395_1697	ENOG4108TWJ	NADH dehydrogenase subunit 5
VC395_1699	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
VC395_1701	ENOG4105CH6	catalase
VC395_1705	ENOG4107FQX	Alpha-acetolactate decarboxylase
VC395_1706	ENOG4105C7K	acetolactate synthase
VC395_1708	ENOG4105BZU	Histidine kinase
VC395_1709	ENOG4106TD9	Diguanylate cyclase
VC395_1710	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
VC395_1711	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
VC395_1712	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
VC395_1718	ENOG4107R88	Chemotaxis protein (CheV)
VC395_1720	ENOG4106YYS	transcriptional regulatory protein
VC395_1721	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
VC395_1723	ENOG4107V40	secretion protein, HlyD family
VC395_1727	ENOG4105CVG	Homoserine O-transsuccinylase
VC395_1728	ENOG41090FY	type IV pilus biogenesis stability protein PilW
VC395_1731	ENOG4108RS6	transposase
VC395_1733	ENOG4108VKG	metal-dependent hydrolase
VC395_1735	ENOG4105F04	LysR family Transcriptional regulator
VC395_1739	ENOG4105DFG	type I secretion outer membrane protein
VC395_1740	ENOG4105CDV	Ompa motb domain protein
VC395_1741	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
VC395_1742	ENOG4105E3Q	saccharopine dehydrogenase
VC395_1744	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
VC395_1747	ENOG4108I0Y	(ABC) transporter
VC395_1748	ENOG4105UQX	Mate efflux family protein
VC395_1749	ENOG4105CGD	Nad-dependent epimerase dehydratase
VC395_1751	ENOG4105C2C	drug resistance transporter, Bcr CflA
VC395_1752	ENOG4105I08	Pseudouridine synthase
VC395_1753	ENOG4105CFI	type iii restriction protein res subunit
VC395_1757	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
VC395_1760	ENOG4108N3W	hemolysin secretion protein
VC395_1769	ENOG4105BZU	Histidine kinase
VC395_1770	ENOG4105BZU	Histidine kinase
VC395_1772	ENOG4105CJW	magnesium transporter
VC395_1775	ENOG4105C44	Serine transporter
VC395_1777	ENOG4105CJ1	ABC, transporter
VC395_1778	ENOG4107QWP	ABC-2 type transporter
VC395_1780	ENOG4105XZD	Fe-S protein
VC395_1782	ENOG4105VNH	ABC transporter solute-binding protein
VC395_1783	ENOG4105CXZ	ABC transporter, permease
VC395_1784	ENOG4108VGW	abc transporter atp-binding protein
VC395_1785	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
VC395_1786	ENOG4108W1A	pseudouridine synthase
VC395_1787	ENOG4105C8J	)-transporter
VC395_1788	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
VC395_1789	ENOG4105C28	cystathionine
VC395_1790	ENOG4108R3E	Dna-3-methyladenine glycosylase i
VC395_1793	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
VC395_1796	ENOG41087YS	Phage shock protein A
VC395_1797	ENOG4105E51	psp operon transcriptional activator
VC395_1798	ENOG4105DEF	Extracellular solute-binding protein, family 5
VC395_1799	ENOG4108I5W	peptide transport system, permease protein
VC395_1800	ENOG4108EU3	peptide transport system, permease
VC395_1801	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
VC395_1802	ENOG4108JQ2	peptide transport system atp-binding protein
VC395_1805	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
VC395_1810	ENOG4107QY8	reductase
VC395_1813	ENOG4105TMB	Formate nitrite transporter
VC395_1815	ENOG4108535	NAD dependent epimerase/dehydratase family
VC395_1816	ENOG4105GFG	DUF218 domain
VC395_1818	ENOG4107835	probably involved in intracellular septation (By similarity)
VC395_1819	ENOG4105NAU	thioesterase Superfamily protein
VC395_1820	ENOG4105K9H	YciI-like protein
VC395_1822	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
VC395_1823	ENOG4105DZ2	Transcriptional regulator
VC395_1828	ENOG4105CCT	upf0313 protein
VC395_1831	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
VC395_1832	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
VC395_1833	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
VC395_1834	ENOG4106371	Methyltransferase
VC395_1835	ENOG4107S90	membrAne
VC395_1836	ENOG4106WF9	DNA-binding transcriptional regulator TorR
VC395_1837	ENOG4108SBI	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
VC395_1838	ENOG4105ETE	Transcriptional regulator (LacI family
VC395_1839	ENOG4105HP8	regulator of competence-specific genes
VC395_1843	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
VC395_1844	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
VC395_1846	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
VC395_1847	ENOG4105RKX	Protein of unknown function (DUF2498)
VC395_1848	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
VC395_1851	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
VC395_1852	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
VC395_1853	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
VC395_1855	ENOG4107QPN	acyl-Coa dehydrogenase
VC395_1856	ENOG41067SE	Tetr family transcriptional regulator
VC395_1859	ENOG4105MTM	Protein of unknown function (DUF1496)
VC395_1860	ENOG4105C26	Dehydrogenase
VC395_1861	ENOG4108R86	Transcriptional regulator
VC395_1868	ENOG4105F1S	paraquat-inducible protein a
VC395_1869	ENOG4105DY2	Paraquat-inducible protein b
VC395_1873	ENOG4105DFP	Integrase
VC395_1875	ENOG4105C0D	helicase
VC395_1879	ENOG4105DZR	Type I site-specific deoxyribonuclease
VC395_1883	ENOG4105CVR	type I restriction-modification system
VC395_1887	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
VC395_1888	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
VC395_1889	ENOG4105QEK	Transcriptional regulator
VC395_1891	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
VC395_1892	ENOG41069H7	transport system small permease component
VC395_1893	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
VC395_1895	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
VC395_1896	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
VC395_1897	ENOG4105CE4	GlcNAc 6-P deacetylase
VC395_1898	ENOG4108478	ec 3.2.1.18
VC395_1900	ENOG4108YGG	dna repair protein
VC395_1905	ENOG4108NYK	Tape measure protein
VC395_1929	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
VC395_1931	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
VC395_1932	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
VC395_1934	ENOG4105C26	Dehydrogenase
VC395_1936	ENOG4105DM4	PTS System
VC395_1937	ENOG4105DM4	PTS System
VC395_1938	ENOG4108YRF	PTS System
VC395_1940	ENOG4106R3P	AraC family transcriptional regulator
VC395_1941	ENOG4105DM4	PTS System
VC395_1942	ENOG4105EIP	mannose-6-phosphate isomerase
VC395_1943	ENOG4108RNS	Exports L-alanine (By similarity)
VC395_1946	ENOG4105BZU	Histidine kinase
VC395_1948	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
VC395_1950	ENOG4105KCK	Peptidoglycan-associated lipoprotein
VC395_1951	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
VC395_1953	ENOG4105M8F	Biopolymer transport protein exbD tolR
VC395_1954	ENOG4105E02	MotA TolQ exbB proton channel
VC395_1956	ENOG4105KJB	cyd operon protein YbgE
VC395_1958	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
VC395_1959	ENOG4105C4M	(Ubiquinol oxidase) subunit I
VC395_1960	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
VC395_1961	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
VC395_1962	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
VC395_1963	ENOG4105C8N	cysteinyl-tRNA synthetase
VC395_1964	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
VC395_1965	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
VC395_1966	ENOG4105D58	Diguanylate phosphodiesterase
VC395_1969	ENOG4105ZU8	porin-like protein H
VC395_1970	ENOG4105DVT	helicase
VC395_1971	ENOG4105EJ9	Membrane
VC395_1972	ENOG4108URS	primosomal replication protein n''
VC395_1973	ENOG4106428	Protein of unknown function (DUF2496)
VC395_1974	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_1975	ENOG4105CGK	Exodeoxyribonuclease III
VC395_1976	ENOG4106YG3	ABC transporter
VC395_1977	ENOG4105DSP	amino acid AbC transporter
VC395_1978	ENOG4105E89	ABC transporter
VC395_1979	ENOG4108JEH	abc transporter atp-binding protein
VC395_1981	ENOG4105C6N	Formate acetyltransferase
VC395_1983	ENOG4108N3W	hemolysin secretion protein
VC395_1984	ENOG4105F1A	Pyruvate formate-lyase
VC395_1986	ENOG4105XWI	UPF0304 protein
VC395_1987	ENOG4105CYN	Serine protein kinase
VC395_1988	ENOG4106AKX	UPF0229 protein
VC395_1989	ENOG4105ED1	spovr family
VC395_1990	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
VC395_1992	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
VC395_1993	ENOG4105BZ1	(ABC) transporter
VC395_1994	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
VC395_1997	ENOG4105D60	lipoprotein releasing system transmembrane protein
VC395_1998	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
VC395_1999	ENOG4105D60	lipoprotein releasing system transmembrane protein
VC395_2001	ENOG4108JA2	transcriptioN-repair coupling factor
VC395_2003	ENOG4106M3D	hemolysin
VC395_2005	ENOG4105CEP	NADH dehydrogenase
VC395_2012	ENOG4105K59	histidine triad (HIT) protein
VC395_2013	ENOG4108NVR	Methyl-accepting chemotaxis
VC395_2015	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
VC395_2016	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
VC395_2017	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
VC395_2018	ENOG4105CNU	cell division protein FtsK
VC395_2019	ENOG4105EW9	transcriptional regulator AsnC family
VC395_2020	ENOG4105DCF	alanine dehydrogenase
VC395_2022	ENOG4107R11	Transcriptional regulator
VC395_2025	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
VC395_2026	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
VC395_2027	ENOG4105CFV	Tetratricopeptide repeat protein
VC395_2028	ENOG4105Q4A	inner membrane protein yciS
VC395_2029	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
VC395_2030	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
VC395_2031	ENOG4105CAT	Cytidine monophosphate kinase
VC395_2032	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
VC395_2033	ENOG4105EIN	peptidylprolyl cis-trans isomerase
VC395_2034	ENOG4105K70	DNA-binding protein
VC395_2035	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
VC395_2036	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
VC395_2037	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
VC395_2038	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
VC395_2041	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VC395_2042	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
VC395_2043	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
VC395_2044	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
VC395_2046	ENOG4105CNG	UPF0061 protein
VC395_2049	ENOG4105BZU	Histidine kinase
VC395_2051	ENOG4108HPI	phosphatidate Cytidylyltransferase
VC395_2057	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
VC395_2062	ENOG4105JQN	Transcriptional regulator
VC395_2065	ENOG4107QY8	reductase
VC395_2066	ENOG4105CUW	cytochrome C-TYPE protein
VC395_2067	ENOG410662T	chitinase
VC395_2068	ENOG4105D9N	nucleoside
VC395_2070	ENOG4105JQN	Transcriptional regulator
VC395_2071	ENOG4105CVE	Lytic murein transglycosylase
VC395_2072	ENOG4105VNG	YcgL domain-containing protein
VC395_2074	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
VC395_2075	ENOG4107QMS	site-determining protein
VC395_2076	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
VC395_2081	ENOG4107S74	Lysophospholipid transporter LplT
VC395_2082	ENOG4108N3W	hemolysin secretion protein
VC395_2083	ENOG4108JCI	Transcriptional regulator
VC395_2085	ENOG4105DKK	Benzoate
VC395_2086	ENOG4105CEY	Amp-dependent synthetase and ligase
VC395_2087	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
VC395_2088	ENOG4108IPT	Naphthoate synthase
VC395_2089	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
VC395_2090	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
VC395_2091	ENOG4105E4F	Isochorismate synthase
VC395_2092	ENOG4105CHM	Aminotransferase
VC395_2093	ENOG4105DK2	UPF0207 protein
VC395_2094	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
VC395_2099	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
VC395_2100	ENOG4105CEY	Amp-dependent synthetase and ligase
VC395_2101	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
VC395_2104	ENOG41072GX	Peptidase M22 Glycoprotease
VC395_2105	ENOG4105DVT	helicase
VC395_2107	ENOG4105CIY	formyltetrahydrofolate deformylase
VC395_2108	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
VC395_2109	ENOG4105D07	Signal peptide peptidase, SppA
VC395_2110	ENOG4105HDK	L-asparaginase
VC395_2111	ENOG4105VUT	cytoplasmic protein
VC395_2113	ENOG4105E0X	reductase
VC395_2115	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
VC395_2116	ENOG4105DSB	aldose 1-epimerase
VC395_2118	ENOG4105DHI	Methyltransferase
VC395_2121	ENOG4107R88	Chemotaxis protein (CheV)
VC395_2122	ENOG4105DAG	ROK family
VC395_2123	ENOG4105CA9	Pyruvate kinase
VC395_2124	ENOG4108NRW	Phospholipase, patatin family
VC395_2127	ENOG4105C8J	)-transporter
VC395_2128	ENOG4105CI1	PTS System
VC395_2129	ENOG4105F8V	Hydrolase, tatD family
VC395_2130	ENOG4107QRG	dna polymerase iii
VC395_2131	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
VC395_2132	ENOG4105HHA	aminodeoxychorismate lyase
VC395_2133	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
VC395_2134	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
VC395_2135	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
VC395_2136	ENOG4105CHR	reductase
VC395_2137	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
VC395_2138	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
VC395_2139	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
VC395_2140	ENOG4105VGS	50s ribosomal protein l32
VC395_2141	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
VC395_2142	ENOG4108UHJ	MAF-like protein
VC395_2143	ENOG4105EI2	Pseudouridine synthase
VC395_2145	ENOG4105C03	ribonuclease
VC395_2146	ENOG4105CHH	sulfate transporter
VC395_2148	ENOG4108EKI	Dehydrogenase
VC395_2150	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
VC395_2151	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
VC395_2152	ENOG4105DFD	Na H antiporter
VC395_2154	ENOG4106V8H	Nucleoid-associated protein
VC395_2156	ENOG4105E68	Sulfatase
VC395_2157	ENOG4105DGU	Histone deacetylase
VC395_2158	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
VC395_2159	ENOG4105M2J	Glutaredoxin
VC395_2160	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
VC395_2163	ENOG410903C	(LipO)protein
VC395_2165	ENOG4105KWW	Biogenesis protein
VC395_2166	ENOG4107QX9	Thiol disulfide interChange protein
VC395_2167	ENOG4105DA4	cytochrome c-type biogenesis protein
VC395_2168	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
VC395_2169	ENOG41067VX	Heme exporter protein
VC395_2170	ENOG41060IM	Heme exporter protein
VC395_2171	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
VC395_2172	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
VC395_2174	ENOG4108V3W	Chemotaxis protein, CheW
VC395_2176	ENOG4107QJE	Chromosome Partitioning Protein
VC395_2177	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
VC395_2178	ENOG4105CBS	Chea signal transduction histidine kinase
VC395_2179	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
VC395_2180	ENOG4108VYJ	response regulator receiver protein
VC395_2181	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VC395_2182	ENOG4107R21	site-determining protein
VC395_2183	ENOG4105FZW	flagellar biosynthesis regulator FlhF
VC395_2184	ENOG4105D7B	Flagellar biosynthesis protein flha
VC395_2185	ENOG4108BY2	phosphohistidine phosphatase
VC395_2187	ENOG4108JQM	Insulinase (Peptidase family M16)
VC395_2189	ENOG4105C75	arginyL-tRNA synthetase
VC395_2193	ENOG4105XFK	Ferrous iron transport protein A
VC395_2195	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
VC395_2196	ENOG4105NXV	High-affinity zinc uptake system protein
VC395_2197	ENOG4105FDK	ABC transporter
VC395_2198	ENOG4105FAV	ABC, transporter
VC395_2199	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
VC395_2200	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
VC395_2201	ENOG4105C7S	Dehydrogenase
VC395_2202	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
VC395_2203	ENOG4105E33	succinate dehydrogenase
VC395_2204	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
VC395_2205	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
VC395_2206	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
VC395_2207	ENOG4105BZN	citrate synthase
VC395_2208	ENOG4107QNR	UPF0135 protein
VC395_2210	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
VC395_2211	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
VC395_2212	ENOG4105EV9	Alpha Beta Hydrolase
VC395_2214	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
VC395_2215	ENOG41067MG	lrgb family
VC395_2216	ENOG4105VAW	lrga family
VC395_2218	ENOG4105CMU	LysR family (Transcriptional regulator
VC395_2220	ENOG41090R7	Ferric uptake
VC395_2221	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
VC395_2222	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
VC395_2223	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
VC395_2224	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
VC395_2225	ENOG4105Q8W	reductase
VC395_2226	ENOG4105MH2	YfcL protein
VC395_2227	ENOG4108BPE	-transporting atpase
VC395_2229	ENOG4105EN6	Membrane
VC395_2230	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
VC395_2232	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
VC395_2234	ENOG4105D00	flagellar biosynthetic protein flhB
VC395_2235	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
VC395_2236	ENOG4105VS8	Flagellar biosynthetic protein fliq
VC395_2237	ENOG4105CN7	Flagellar biosynthetic protein FliP
VC395_2238	ENOG4105VTB	flagellar biosynthesis protein fliO
VC395_2239	ENOG4105DD5	Flagellar motor switch protein
VC395_2240	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
VC395_2241	ENOG4105X6C	Flagellar basal body-associated protein FliL
VC395_2244	ENOG4108JIR	Flagellum-specific ATP synthase
VC395_2245	ENOG4105W2B	Flagellar assembly protein
VC395_2246	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
VC395_2247	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
VC395_2248	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
VC395_2249	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VC395_2250	ENOG4105BZU	Histidine kinase
VC395_2251	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VC395_2252	ENOG4105MQ3	flagellar protein FliS
VC395_2254	ENOG4107W9T	flagellar hook-associated
VC395_2255	ENOG41063QE	flagellar protein FlaG
VC395_2256	ENOG4105I03	Flagellin
VC395_2257	ENOG4105I03	Flagellin
VC395_2258	ENOG4105I03	Flagellin
VC395_2259	ENOG4105EZR	dyp-type peroxidase family protein
VC395_2260	ENOG4105QZU	Inner membrane protein YfeZ
VC395_2264	ENOG4105KUZ	arsenate reductase
VC395_2266	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
VC395_2270	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
VC395_2271	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
VC395_2274	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VC395_2275	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_2278	ENOG4105ERG	peptidase m48, ste24p
VC395_2279	ENOG4105K89	arsenate reductase
VC395_2280	ENOG4105CS1	NAD(P)H quinone oxidoreductase
VC395_2285	ENOG4105C2W	permease
VC395_2286	ENOG4108Z66	YbaK ebsC protein
VC395_2288	ENOG4105CGH	5'-nucleotidase
VC395_2289	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
VC395_2290	ENOG41063JG	Transcriptional regulator
VC395_2291	ENOG4108YY7	Invasion gene expression up-regulator SirB
VC395_2292	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
VC395_2293	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
VC395_2294	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
VC395_2295	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
VC395_2296	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
VC395_2297	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
VC395_2298	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
VC395_2299	ENOG4105C3G	gtp-binding protein
VC395_2301	ENOG4108RS6	transposase
VC395_2303	ENOG4105I03	Flagellin
VC395_2304	ENOG4105I03	Flagellin
VC395_2308	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
VC395_2309	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
VC395_2310	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
VC395_2311	ENOG4105CGA	flagellar basal-body rod protein FlgG
VC395_2312	ENOG4108KPB	Flagellar basal-body rod protein FlgF
VC395_2313	ENOG4105BZE	flagellar hook protein, FlgE
VC395_2314	ENOG4105W00	Flagellar hook capping protein
VC395_2315	ENOG4108ZC9	flagellar basal-body rod protein flgc
VC395_2316	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
VC395_2317	ENOG4105BZU	Histidine kinase
VC395_2318	ENOG4107R88	Chemotaxis protein (CheV)
VC395_2325	ENOG4105C0W	non-ribosomal peptide synthetase
VC395_2326	ENOG4105Q26	Siderophore-interacting protein
VC395_2327	ENOG4107RBR	Receptor
VC395_2329	ENOG4105UYK	outer membrane protein a
VC395_2330	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
VC395_2331	ENOG4105C59	p-type ATPase
VC395_2333	ENOG4105E2D	ec 3.2.1.52
VC395_2336	ENOG4105MBR	gumn family
VC395_2338	ENOG4108DG9	Smr protein MutS2
VC395_2339	ENOG4105FE9	pseudouridine synthase
VC395_2340	ENOG4105BZU	Histidine kinase
VC395_2341	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
VC395_2342	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
VC395_2343	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
VC395_2345	ENOG4105E7A	Glutamine amidotransferase
VC395_2346	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
VC395_2347	ENOG4107QPN	acyl-Coa dehydrogenase
VC395_2349	ENOG4108JDX	DNA polymerase iii, epsilon subunit
VC395_2350	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
VC395_2351	ENOG4105D1A	Methyltransferase
VC395_2352	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
VC395_2353	ENOG4105E9H	Lytic Murein transglycosylase
VC395_2355	ENOG4108YZA	Nitrogen regulatory protein pii
VC395_2356	ENOG4105PY6	Phenolic acid decarboxylase
VC395_2357	ENOG4105N7H	Cytochrome
VC395_2358	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
VC395_2360	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
VC395_2361	ENOG4105C0B	DNA polymerase III (alpha subunit)
VC395_2362	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
VC395_2363	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VC395_2364	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VC395_2365	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
VC395_2366	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VC395_2367	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
VC395_2369	ENOG4105DZP	Membrane-associated zinc metalloprotease
VC395_2370	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
VC395_2371	ENOG4105KNE	Phosphatidate cytidylyltransferase
VC395_2372	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
VC395_2373	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
VC395_2374	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
VC395_2375	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
VC395_2376	ENOG4105CE9	30S ribosomal protein S2
VC395_2377	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
VC395_2378	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
VC395_2380	ENOG4108T8E	UPF0325 protein
VC395_2381	ENOG4108ZAI	phosphatidylglycerophosphatase a
VC395_2382	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
VC395_2383	ENOG4107YIM	Involved in the transcription termination process (By similarity)
VC395_2384	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
VC395_2387	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
VC395_2388	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
VC395_2389	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
VC395_2390	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
VC395_2391	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
VC395_2393	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
VC395_2394	ENOG4105C7N	Xanthine uracil vitamin C permease
VC395_2395	ENOG4105CIN	aminoacyl-histidine dipeptidase
VC395_2396	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VC395_2397	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VC395_2399	ENOG4105C8J	)-transporter
VC395_2401	ENOG4105BZU	Histidine kinase
VC395_2403	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
VC395_2405	ENOG4105CJ2	(LipO)protein
VC395_2406	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
VC395_2407	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VC395_2408	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VC395_2409	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VC395_2410	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VC395_2411	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VC395_2412	ENOG4105M85	Bola protein
VC395_2413	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
VC395_2415	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
VC395_2416	ENOG4105EYM	Major Facilitator superfamily
VC395_2418	ENOG4105K6V	RNA polymerase
VC395_2421	ENOG4105DRB	nucleoside-specific channel-forming protein
VC395_2423	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
VC395_2424	ENOG4107S0N	DJ-1 family
VC395_2425	ENOG4105C9B	Cysteine desulfurase
VC395_2426	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
VC395_2427	ENOG4105CUZ	uba thif-type nad fad binding protein
VC395_2428	ENOG4105CA3	membrane-bound lytic murein transglycosylase
VC395_2432	ENOG4107QZM	n-acetylglutamate synthase
VC395_2435	ENOG4107QYX	exodeoxyribonuclease v alpha
VC395_2436	ENOG4107QKA	exodeoxyribonuclease V beta
VC395_2438	ENOG4105DSY	exodeoxyribonuclease V, gamma
VC395_2442	ENOG4105X2V	dna damage-inducible protein
VC395_2444	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
VC395_2447	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
VC395_2448	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VC395_2451	ENOG4108Y51	tRNA-binding protein
VC395_2453	ENOG4105CNT	hydrolase family 2
VC395_2455	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
VC395_2456	ENOG4108IQE	Amp-dependent synthetase and ligase
VC395_2457	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
VC395_2458	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
VC395_2460	ENOG4105EAC	phosphoserine phosphatase
VC395_2462	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
VC395_2463	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
VC395_2464	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
VC395_2465	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
VC395_2467	ENOG4105D9N	nucleoside
VC395_2468	ENOG4105EYA	deoxyribonuclease
VC395_2471	ENOG4105BZG	amino acid carrier protein
VC395_2474	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
VC395_2475	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
VC395_2476	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
VC395_2477	ENOG4105D98	threonine synthase
VC395_2478	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
VC395_2481	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
VC395_2483	ENOG41065U4	response regulator
VC395_2484	ENOG4105BZU	Histidine kinase
VC395_2486	ENOG4105N5T	Radical SAM Protein
VC395_2491	ENOG4105CBC	glutamate synthase
VC395_2492	ENOG4105BZ8	glutamate synthase
VC395_2494	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
VC395_2496	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
VC395_2497	ENOG4105EN6	Membrane
VC395_2498	ENOG4105VP0	transcriptional regulator, lysR family
VC395_2499	ENOG4105EJ9	Membrane
VC395_2500	ENOG4107RRE	RNA-directed DNA polymerase
VC395_2504	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
VC395_2505	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
VC395_2506	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
VC395_2507	ENOG4105M6F	mutator MutT protein
VC395_2509	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
VC395_2511	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VC395_2512	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
VC395_2513	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
VC395_2514	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
VC395_2515	ENOG4105DFU	Cell wall formation (By similarity)
VC395_2516	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
VC395_2518	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
VC395_2519	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
VC395_2520	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
VC395_2521	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
VC395_2522	ENOG4105CJN	penicillin-binding protein
VC395_2523	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
VC395_2524	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
VC395_2527	ENOG4107QN2	dihydrolipoyl dehydrogenase
VC395_2528	ENOG4107QSN	dihydrolipoamide acetyltransferase
VC395_2529	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
VC395_2530	ENOG41073TP	transcriptional regulator
VC395_2531	ENOG4105CGH	5'-nucleotidase
VC395_2532	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
VC395_2533	ENOG4105T95	Thiol disulfide interChange protein
VC395_2534	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
VC395_2535	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
VC395_2537	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
VC395_2539	ENOG4107QHF	type ii secretion system protein e
VC395_2540	ENOG4105D7Q	type ii secretion system
VC395_2541	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
VC395_2542	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
VC395_2543	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
VC395_2544	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
VC395_2545	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VC395_2546	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VC395_2547	ENOG4105IPS	esterase
VC395_2548	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
VC395_2549	ENOG4108SX3	cytoplasmic protein
VC395_2550	ENOG41087AY	ADP-Ribose pyrophosphatase
VC395_2551	ENOG4105DFG	type I secretion outer membrane protein
VC395_2552	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
VC395_2553	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
VC395_2554	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_2555	ENOG4105I7R	Adenylate cyclase
VC395_2556	ENOG4107IX6	phosphate transport regulator
VC395_2557	ENOG4105CJ3	phosphate transporter
VC395_2558	ENOG4106MWK	domain protein
VC395_2561	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
VC395_2562	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
VC395_2563	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
VC395_2565	ENOG4105DXN	mazG family
VC395_2566	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
VC395_2567	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
VC395_2568	ENOG4105BZU	Histidine kinase
VC395_2572	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
VC395_2573	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
VC395_2574	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
VC395_2575	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
VC395_2576	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
VC395_2577	ENOG4105C3F	Signal peptidase i
VC395_2578	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
VC395_2579	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
VC395_2580	ENOG4105VQK	sigma E regulatory protein, MucB RseB
VC395_2582	ENOG4105EMN	RNA polymerase sigma factor
VC395_2584	ENOG4108IYU	L-aspartate oxidase
VC395_2586	ENOG4105Y75	tpr repeat protein
VC395_2587	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
VC395_2589	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
VC395_2590	ENOG4105D0A	hydroxylase
VC395_2592	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
VC395_2593	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
VC395_2594	ENOG4105E66	phosphoriboisomerase A
VC395_2595	ENOG4108JQ1	Dehydrogenase
VC395_2596	ENOG4108ZP8	Acetolactate synthase small subunit
VC395_2597	ENOG4105C7K	acetolactate synthase
VC395_2598	ENOG4108IQE	Amp-dependent synthetase and ligase
VC395_2599	ENOG41064T2	transcriptional regulator, lysR family
VC395_2604	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
VC395_2605	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
VC395_2606	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
VC395_2607	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
VC395_2611	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
VC395_2613	ENOG4108K5H	permease YjgP YjgQ family protein
VC395_2614	ENOG4108M8S	permease YjgP YjgQ family protein
VC395_2615	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
VC395_2616	ENOG4105MYG	DNA polymerase iii, chi subunit
VC395_2617	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
VC395_2618	ENOG4105C5I	Dehydrogenase
VC395_2619	ENOG4105D3G	Pseudouridine synthase
VC395_2620	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
VC395_2621	ENOG4108IAB	Phoh family
VC395_2622	ENOG4105DBV	ornithine carbamoyltransferase
VC395_2624	ENOG4105CXT	aspartate transcarbamylase
VC395_2625	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
VC395_2626	ENOG4105KME	endoribonuclease L-psp
VC395_2627	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
VC395_2628	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
VC395_2629	ENOG4105VFK	BolA family
VC395_2631	ENOG4105E3I	toluene tolerance
VC395_2632	ENOG4107PE3	Mammalian cell entry related domain protein
VC395_2633	ENOG4105CY3	ABC transporter, permease
VC395_2634	ENOG4105DHJ	ABC, transporter
VC395_2637	ENOG4105C2X	Arabinose 5-phosphate isomerase
VC395_2638	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
VC395_2640	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
VC395_2641	ENOG4108IUZ	ABC transporter
VC395_2642	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VC395_2643	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
VC395_2644	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
VC395_2646	ENOG41080Z8	PHOSPHOCARRIER protein
VC395_2647	ENOG4105CJW	magnesium transporter
VC395_2648	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
VC395_2649	ENOG4105N42	UPF0307 protein
VC395_2650	ENOG4107T0D	ABC, transporter
VC395_2651	ENOG4106SMU	thiamine transporter membrane protein
VC395_2652	ENOG4105DP9	ABC transporter
VC395_2654	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
VC395_2655	ENOG4105DFU	Cell wall formation (By similarity)
VC395_2657	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
VC395_2658	ENOG4105F0N	pyrophosphate phospho-hydrolase
VC395_2659	ENOG41066HZ	AIG2-like family
VC395_2661	ENOG4105CFU	surface antigen
VC395_2662	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
VC395_2663	ENOG4108UUE	Transcriptional regulator
VC395_2666	ENOG4107R39	(ABC) transporter
VC395_2670	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
VC395_2671	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
VC395_2672	ENOG4105C11	sulfate adenylyltransferase), subunit 2
VC395_2673	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
VC395_2674	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
VC395_2676	ENOG4105C1J	atp-dependent rna helicase
VC395_2677	ENOG4107YB6	acetyltransferase, (GNAT) family
VC395_2678	ENOG4108SXK	Transporter Drug Metabolite Exporter family
VC395_2679	ENOG4108UBT	opacity-associated protein
VC395_2680	ENOG4108V1T	peptidylprolyl cis-trans isomerase
VC395_2681	ENOG4108RS6	transposase
VC395_2683	ENOG4108ZT0	50S ribosomal protein l17
VC395_2684	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VC395_2685	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
VC395_2686	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
VC395_2687	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VC395_2689	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
VC395_2690	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
VC395_2691	ENOG4105VPB	50S ribosomal protein L30
VC395_2692	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
VC395_2693	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
VC395_2694	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
VC395_2695	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
VC395_2696	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
VC395_2697	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VC395_2698	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
VC395_2699	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
VC395_2700	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
VC395_2701	ENOG41083MP	50s ribosomal protein l29
VC395_2702	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
VC395_2703	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
VC395_2704	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
VC395_2705	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
VC395_2706	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VC395_2707	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
VC395_2708	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
VC395_2709	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
VC395_2710	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
VC395_2711	ENOG4105C2N	RNA methyltransferase TrmH family group 3
VC395_2712	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
VC395_2713	ENOG4105E68	Sulfatase
VC395_2714	ENOG4108UV7	flagellar protein motX
VC395_2715	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
VC395_2716	ENOG4105D44	asparaginase
VC395_2717	ENOG4108YZY	peptidylprolyl cis-trans isomerase
VC395_2720	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
VC395_2721	ENOG4105C5H	ABC transporter
VC395_2723	ENOG4105DNZ	Alpha Beta Hydrolase
VC395_2726	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
VC395_2727	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
VC395_2729	ENOG4105C26	Dehydrogenase
VC395_2731	ENOG4105C8Y	Acetylornithine aminotransferase
VC395_2732	ENOG4105DDQ	anthranilate synthase
VC395_2733	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
VC395_2736	ENOG4105C31	Tryptophanyl-tRNA synthetase
VC395_2737	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
VC395_2738	ENOG4105DJV	ribulose-phosphate 3-epimerase
VC395_2739	ENOG4105DFE	Dna adenine methylase
VC395_2741	ENOG4105D49	3-dehydroquinate synthase
VC395_2742	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
VC395_2743	ENOG4105E4G	Type IV pilus
VC395_2748	ENOG4108JQC	penicillin-binding protein 1A
VC395_2750	ENOG4105EHV	domain protein
VC395_2751	ENOG4107QN2	dihydrolipoyl dehydrogenase
VC395_2754	ENOG4105CH7	arginosuccinase
VC395_2755	ENOG4105CDH	Citrulline--aspartate ligase
VC395_2756	ENOG4105CAS	nag kinase
VC395_2757	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
VC395_2758	ENOG4105CWC	Acetylornithine deacetylase
VC395_2759	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
VC395_2762	ENOG4105D7W	serine acetyltransferase
VC395_2764	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
VC395_2766	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
VC395_2767	ENOG4107YZP	Rhodanese domain protein
VC395_2768	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
VC395_2770	ENOG4105E33	succinate dehydrogenase
VC395_2771	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
VC395_2772	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
VC395_2773	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
VC395_2774	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
VC395_2777	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
VC395_2778	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
VC395_2783	ENOG4105CP7	Triose-phosphate isomerase
VC395_2785	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
VC395_2786	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
VC395_2787	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
VC395_2788	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
VC395_2789	ENOG41063M6	Cell Division Protein
VC395_2790	ENOG4105ETE	Transcriptional regulator (LacI family
VC395_2791	ENOG4105C25	Primosomal protein n'
VC395_2792	ENOG4105VFB	Binds the 23S rRNA (By similarity)
VC395_2794	ENOG4105C6K	Malic enzyme
VC395_2795	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
VC395_2796	ENOG4105C28	cystathionine
VC395_2797	ENOG4105CFH	Aspartokinase
VC395_2798	ENOG4105SYT	Methylenetetrahydrofolate reductase
VC395_2799	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
VC395_2801	ENOG4105CBT	Fructose-1,6-bisphosphatase
VC395_2802	ENOG4105CTQ	phosphohexokinase
VC395_2803	ENOG41076HS	cation diffusion facilitator family transporter
VC395_2805	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
VC395_2806	ENOG4105E0F	Histidine kinase
VC395_2808	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
VC395_2809	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
VC395_2810	ENOG4105BZU	Histidine kinase
VC395_2811	ENOG4108IJ0	Aspartate ammonia-lyase
VC395_2812	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
VC395_2814	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
VC395_2816	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
VC395_2818	ENOG4107QN1	sodium solute
VC395_2819	ENOG4105EX9	Membrane
VC395_2820	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
VC395_2821	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
VC395_2822	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
VC395_2823	ENOG4105CB5	ATP-dependent DNA helicase recG
VC395_2824	ENOG4105C2W	permease
VC395_2825	ENOG4105E0F	Histidine kinase
VC395_2826	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
VC395_2827	ENOG4108RRZ	Transcription elongation factor GreB
VC395_2828	ENOG4105BZM	domain protein
VC395_2830	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
VC395_2831	ENOG4105MJ2	Competence protein
VC395_2832	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
VC395_2833	ENOG4107RK2	ADP-ribose diphosphatase NudE
VC395_2834	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
VC395_2835	ENOG4105PIC	general secretion pathway protein N
VC395_2836	ENOG4105U1E	general secretion pathway protein M
VC395_2837	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
VC395_2838	ENOG4108RTD	type II secretion system protein K
VC395_2839	ENOG4108WWZ	General secretion pathway protein J
VC395_2840	ENOG4105X5Z	General secretion pathway protein I
VC395_2841	ENOG4105VWV	general secretion pathway protein h
VC395_2842	ENOG4108VAU	general secretion pathway protein G
VC395_2843	ENOG4105D7Q	type ii secretion system
VC395_2844	ENOG4107QHF	type ii secretion system protein e
VC395_2846	ENOG4108XKW	General secretion pathway protein C
VC395_2847	ENOG4105VEJ	Heat shock protein
VC395_2848	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
VC395_2850	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
VC395_2852	ENOG4105SUU	thioesterase domain
VC395_2853	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
VC395_2855	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
VC395_2858	ENOG4105C5F	glutamine synthetase
VC395_2860	ENOG4105CUX	Signal transduction histidine kinase
VC395_2861	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VC395_2862	ENOG4105BZU	Histidine kinase
VC395_2863	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
VC395_A0006	ENOG4105CDY	transcriptional regulatory protein
VC395_A0007	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
VC395_A0008	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_A0009	ENOG4108YYI	Protein of unknown function (DUF2810)
VC395_A0010	ENOG41061ZR	Transcriptional regulator
VC395_A0011	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
VC395_A0012	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
VC395_A0013	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
VC395_A0014	ENOG4108WC9	type VI secretion system effector, hcp1 family
VC395_A0015	ENOG4105CS6	Rhs element vgr protein
VC395_A0020	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
VC395_A0022	ENOG4105C8P	)-transporter
VC395_A0023	ENOG4108Q67	UPF0319 protein
VC395_A0027	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_A0031	ENOG4105EYK	Phosphatidylglycerophosphatase B
VC395_A0032	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
VC395_A0037	ENOG4105D6U	Sodium Glutamate Symporter
VC395_A0038	ENOG4105YE1	PilZ domain
VC395_A0042	ENOG4105EFX	secretion protein, HlyD family
VC395_A0043	ENOG4105KK7	inner membrane protein YiaW
VC395_A0044	ENOG4106TD9	Diguanylate cyclase
VC395_A0047	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
VC395_A0049	ENOG4107SEY	Conserved Protein
VC395_A0051	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
VC395_A0052	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
VC395_A0054	ENOG4105C1J	atp-dependent rna helicase
VC395_A0056	ENOG4105CUG	Oligopeptidase b
VC395_A0063	ENOG4105CVA	phosphate
VC395_A0064	ENOG4105C8U	phosphate abc transporter
VC395_A0065	ENOG4105E2Z	phosphate ABC transporter (Permease
VC395_A0066	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
VC395_A0067	ENOG4105BZU	Histidine kinase
VC395_A0070	ENOG4105DWD	nucleoside recognition domain protein
VC395_A0071	ENOG4105CHH	sulfate transporter
VC395_A0073	ENOG4105DR5	peptidase
VC395_A0074	ENOG4105BZU	Histidine kinase
VC395_A0075	ENOG4105EQ2	LysR family Transcriptional regulator
VC395_A0076	ENOG4105E5M	Multidrug resistance protein D
VC395_A0077	ENOG4108Z4X	TRANSCRIPTIONal
VC395_A0081	ENOG4105CK2	sodium dicarboxylate symporter
VC395_A0091	ENOG4107RH7	Nicotinate phosphoribosyltransferase
VC395_A0092	ENOG4105D9R	oxidoreductase
VC395_A0094	ENOG4105BZU	Histidine kinase
VC395_A0095	ENOG4107VXZ	Hydrolase
VC395_A0097	ENOG4105D3G	Pseudouridine synthase
VC395_A0109	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
VC395_A0110	ENOG4108JUB	Transcriptional regulator
VC395_A0116	ENOG4105CS6	Rhs element vgr protein
VC395_A0120	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
VC395_A0121	ENOG4105C2J	ABC transporter
VC395_A0122	ENOG4105CNN	ABC, transporter
VC395_A0123	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
VC395_A0124	ENOG4108RVA	ribokinase
VC395_A0125	ENOG4105ETE	Transcriptional regulator (LacI family
VC395_A0126	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
VC395_A0127	ENOG4108I5U	Uridine phosphorylase
VC395_A0129	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
VC395_A0130	ENOG4105CXY	transporter
VC395_A0134	ENOG4105CQZ	Histidine kinase
VC395_A0135	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VC395_A0140	ENOG4105D5U	fad dependent oxidoreductase
VC395_A0143	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
VC395_A0144	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
VC395_A0145	ENOG4105KJM	monovalent cation h antiporter subunit g
VC395_A0146	ENOG41080TA	Multiple resistance and ph regulation protein f
VC395_A0147	ENOG4105SC1	monovalent cation H antiporter subunit E
VC395_A0148	ENOG4108JPZ	Monovalent cation H antiporter subunit D
VC395_A0149	ENOG4105MKQ	Monovalent cation H antiporter subunit C
VC395_A0150	ENOG4105D65	subunit l
VC395_A0152	ENOG4105Q9Y	Universal stress protein
VC395_A0153	ENOG4105CIC	tryptophan-specific transport protein
VC395_A0154	ENOG4105C0F	tryptophanase EC 4.1.99.1
VC395_A0156	ENOG4105VRT	cytoplasmic protein
VC395_A0158	ENOG4105BZU	Histidine kinase
VC395_A0159	ENOG4105VEQ	Cold shock protein
VC395_A0166	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
VC395_A0167	ENOG41069D7	Methyl-accepting chemotaxis
VC395_A0170	ENOG4105D9N	nucleoside
VC395_A0171	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
VC395_A0173	ENOG4108JUA	Transcriptional regulator
VC395_A0174	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
VC395_A0175	ENOG4105VEQ	Cold shock protein
VC395_A0180	ENOG4108UNF	response regulator
VC395_A0182	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
VC395_A0183	ENOG4105C5I	Dehydrogenase
VC395_A0188	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
VC395_A0189	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
VC395_A0193	ENOG4105MEH	
VC395_A0202	ENOG4105VZ1	Replication Protein
VC395_A0210	ENOG4105ED4	portal protein
VC395_A0241	ENOG4108RS6	transposase
VC395_A0242	ENOG4105C1J	atp-dependent rna helicase
VC395_A0243	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
VC395_A0244	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
VC395_A0245	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
VC395_A0247	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
VC395_A0248	ENOG4105BZU	Histidine kinase
VC395_A0250	ENOG4107S6Z	Na H antiporter
VC395_A0251	ENOG4105E5M	Multidrug resistance protein D
VC395_A0254	ENOG4105BZU	Histidine kinase
VC395_A0255	ENOG4105KUU	lipolytic protein G-D-S-L family
VC395_A0257	ENOG4108N3W	hemolysin secretion protein
VC395_A0258	ENOG4107IFA	Lipase (EC 3.1.1.3)
VC395_A0260	ENOG4107G87	m6 family metalloprotease domain protein
VC395_A0265	ENOG4105DHS	permease protein
VC395_A0266	ENOG4105CM4	permease protein
VC395_A0267	ENOG4108IPW	abc transporter atp-binding protein
VC395_A0272	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
VC395_A0276	ENOG4105ETX	regulatoR
VC395_A0278	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
VC395_A0280	ENOG410667J	hydrolase
VC395_A0286	ENOG4105DS1	cytochrome b561
VC395_A0294	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
VC395_A0295	ENOG4105BZU	Histidine kinase
VC395_A0301	ENOG4107QVI	Methyltransferase, type 11
VC395_A0304	ENOG4105C2C	drug resistance transporter, Bcr CflA
VC395_A0305	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_A0307	ENOG4105DZ1	carboxypeptidase
VC395_A0312	ENOG4108RS6	transposase
VC395_A0313	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VC395_A0314	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
VC395_A0315	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
VC395_A0317	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
VC395_A0319	ENOG4105F2I	Transposase
VC395_A0324	ENOG4105C22	threonyL-tRNA synthetase
VC395_A0325	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
VC395_A0326	ENOG41082NX	50s ribosomal protein l35
VC395_A0327	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
VC395_A0341	ENOG41080ET	plasmid maintenance system killer protein
VC395_A0342	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
VC395_A0345	ENOG4108S58	Phenazine biosynthesis protein PhzF
VC395_A0351	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
VC395_A0364	ENOG4105YGK	Pfam:UPF0157
VC395_A0365	ENOG4105N14	lysine exporter protein LysE YggA
VC395_A0381	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
VC395_A0392	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
VC395_A0395	ENOG4105QNF	Outer membrane lipoprotein
VC395_A0432	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
VC395_A0436	ENOG4105QNF	Outer membrane lipoprotein
VC395_A0447	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
VC395_A0458	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
VC395_A0459	ENOG4105W08	virulence gene repressor rsal
VC395_A0462	ENOG4105F2I	Transposase
VC395_A0463	ENOG4105EQK	-acetyltransferase
VC395_A0466	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
VC395_A0503	ENOG4108RS6	transposase
VC395_A0515	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
VC395_A0527	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
VC395_A0531	ENOG4105RKW	reductase (By
VC395_A0533	ENOG4108I0Y	(ABC) transporter
VC395_A0534	ENOG4105CV6	ABC transporter, permease
VC395_A0535	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
VC395_A0537	ENOG4107R7A	Allophanate hydrolase subunit 2
VC395_A0539	ENOG4105E7W	lamb ycsf family protein
VC395_A0540	ENOG4105CMR	udp-glucose 4-epimerase
VC395_A0541	ENOG4108N3W	hemolysin secretion protein
VC395_A0542	ENOG4105E0U	tyrosine-specific transport protein
VC395_A0545	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
VC395_A0546	ENOG4105C1J	atp-dependent rna helicase
VC395_A0547	ENOG4108IG5	Transcriptional regulator
VC395_A0548	ENOG4106RE7	Cytochrome
VC395_A0549	ENOG4105C5W	Aldolase
VC395_A0550	ENOG4108YZ4	nudix hydrolase
VC395_A0552	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
VC395_A0554	ENOG4105E5Z	arginine transporter ATP-binding subunit
VC395_A0555	ENOG4106PMH	Extracellular solute-binding protein family 3
VC395_A0556	ENOG4105GBT	ABC transporter
VC395_A0557	ENOG4105DMR	ABC, transporter
VC395_A0558	ENOG4105DUM	transcriptional regulator, lysR family
VC395_A0562	ENOG4105K63	Thioredoxin
VC395_A0563	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
VC395_A0564	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
VC395_A0565	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
VC395_A0566	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
VC395_A0568	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
VC395_A0569	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
VC395_A0574	ENOG4108YXG	UPF0502 protein
VC395_A0575	ENOG41082IR	Excinuclease ABC C subunit domain protein
VC395_A0577	ENOG4108QGH	periplasmic
VC395_A0578	ENOG4105BZU	Histidine kinase
VC395_A0585	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
VC395_A0586	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
VC395_A0587	ENOG4105E0C	molybdate abc transporter
VC395_A0588	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
VC395_A0594	ENOG4105EM2	membrane
VC395_A0595	ENOG41088T4	Helicase IV
VC395_A0598	ENOG41080IJ	Diacylglycerol kinase
VC395_A0600	ENOG4108RWI	nicotinamidase
VC395_A0601	ENOG4108Z5K	methylglyoxal synthase
VC395_A0602	ENOG4108SV3	Tmao reductase system periplasmic protein tort
VC395_A0603	ENOG4105BZU	Histidine kinase
VC395_A0604	ENOG4105CA9	Pyruvate kinase
VC395_A0605	ENOG4105CXY	transporter
VC395_A0606	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
VC395_A0608	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
VC395_A0610	ENOG4108I6A	alcohol dehydrogenase
VC395_A0613	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
VC395_A0615	ENOG4105BZU	Histidine kinase
VC395_A0619	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
VC395_A0620	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
VC395_A0622	ENOG4105CHU	acetyl-coa acetyltransferase
VC395_A0624	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
VC395_A0625	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VC395_A0626	ENOG4107RCV	ABC transporter, permease
VC395_A0627	ENOG4105C4Y	ABC transporter
VC395_A0628	ENOG4105CXY	transporter
VC395_A0629	ENOG4105BZU	Histidine kinase
VC395_A0630	ENOG4108KX4	response regulator
VC395_A0631	ENOG4105DHT	Metal Dependent Phosphohydrolase
VC395_A0634	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
VC395_A0637	ENOG4105BZU	Histidine kinase
VC395_A0638	ENOG4105WH1	Two component transcriptional regulator luxr family
VC395_A0639	ENOG4105ETE	Transcriptional regulator (LacI family
VC395_A0646	ENOG4105EJQ	L-serine dehydratase
VC395_A0647	ENOG4105CEE	C4-dicarboxylate transporter
VC395_A0649	ENOG4108N3W	hemolysin secretion protein
VC395_A0650	ENOG4107VXZ	Hydrolase
VC395_A0651	ENOG4108V1T	peptidylprolyl cis-trans isomerase
VC395_A0653	ENOG4108ZG0	Ompa motb domain protein
VC395_A0654	ENOG4108NVR	Methyl-accepting chemotaxis
VC395_A0655	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
VC395_A0656	ENOG4105D7K	pfkb domain protein
VC395_A0657	ENOG4108HKT	sucrose-6-phosphate hydrolase
VC395_A0658	ENOG4105ETE	Transcriptional regulator (LacI family
VC395_A0659	ENOG4105C5Y	PTS System
VC395_A0668	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
VC395_A0670	ENOG41080HT	Transcriptional regulator, arsr family
VC395_A0675	ENOG4108RCM	Nitroreductase
VC395_A0676	ENOG41067V3	Antibiotic biosynthesis monooxygenase
VC395_A0677	ENOG4105ETT	transcriptional Regulator, LysR family
VC395_A0679	ENOG4105RA2	Membrane
VC395_A0682	ENOG4108M3J	Dehydrogenase
VC395_A0686	ENOG4105F2I	Transposase
VC395_A0691	ENOG4105CV1	Transketolase (EC 2.2.1.1)
VC395_A0692	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
VC395_A0694	ENOG4107RHR	regulatoR
VC395_A0695	ENOG4105KHC	sulfurtransferase
VC395_A0697	ENOG4105D06	uba thif-type nad fad binding protein
VC395_A0698	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
VC395_A0699	ENOG4105EUJ	GTP cyclohydrolase i
VC395_A0700	ENOG4105E0X	reductase
VC395_A0701	ENOG4105CKU	formyltetrahydrofolate synthetase
VC395_A0703	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
VC395_A0705	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
VC395_A0707	ENOG4105PAD	Hydrolase
VC395_A0708	ENOG4105NXH	GreA GreB family elongation factor
VC395_A0709	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
VC395_A0710	ENOG4108JPW	Aminotransferase
VC395_A0711	ENOG4107STF	Involved in phosphonate degradation (By similarity)
VC395_A0714	ENOG4107RCV	ABC transporter, permease
VC395_A0718	ENOG4105DUX	Transporter
VC395_A0723	ENOG4105E43	Extracellular solute-binding protein, family 5
VC395_A0724	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
VC395_A0725	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
VC395_A0726	ENOG4108JQ5	ABC transporter
VC395_A0727	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
VC395_A0730	ENOG4105CYM	Glutathione S-transferase
VC395_A0734	ENOG4105KA0	thioesterase Superfamily protein
VC395_A0740	ENOG4105CWB	LysR family transcriptional Regulator
VC395_A0741	ENOG4105CD5	CoA-binding domain protein
VC395_A0743	ENOG4105CPF	Cell wall formation (By similarity)
VC395_A0745	ENOG4108ZJT	translation initiation factor, Sui1
VC395_A0747	ENOG4107927	Cholera enterotoxin, A subunit
VC395_A0748	ENOG4105MQ5	zona occludens toxin
VC395_A0754	ENOG41067QW	Transcriptional regulator
VC395_A0759	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
VC395_A0761	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
VC395_A0762	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
VC395_A0765	ENOG4105BZU	Histidine kinase
VC395_A0767	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
VC395_A0768	ENOG4105BZU	Histidine kinase
VC395_A0775	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
VC395_A0778	ENOG4105DU1	integral membrane protein, terc
VC395_A0779	ENOG4105CGH	5'-nucleotidase
VC395_A0780	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
VC395_A0781	ENOG4108UQ5	membrane protein YcdZ
VC395_A0782	ENOG4105DUM	transcriptional regulator, lysR family
VC395_A0784	ENOG4105TMB	Formate nitrite transporter
VC395_A0785	ENOG4108YYC	ycei family
VC395_A0786	ENOG4105DS1	cytochrome b561
VC395_A0788	ENOG4105EPM	Diguanylate phosphodiesterase
VC395_A0790	ENOG4108RHM	integral membrane protein
VC395_A0793	ENOG4105C08	Histidine kinase
VC395_A0794	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
VC395_A0795	ENOG4105DFH	Transport of potassium into the cell (By similarity)
VC395_A0796	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
VC395_A0797	ENOG4105CKI	cobalamin synthesis protein
VC395_A0798	ENOG4105CMQ	Chloride channel
VC395_A0801	ENOG4107KBT	8-Amino-7-oxononanoate synthase
VC395_A0802	ENOG4108MGY	Histidine kinase
VC395_A0803	ENOG4105EYH	Exonuclease
VC395_A0805	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
VC395_A0806	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
VC395_A0807	ENOG4105DE4	1-phosphofructokinase
VC395_A0808	ENOG4105DM4	PTS System
VC395_A0809	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VC395_A0810	ENOG4105CGF	Aromatic amino acid aminotransferase
VC395_A0811	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
VC395_A0812	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
VC395_A0822	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
VC395_A0825	ENOG4107RE1	Inosine-guanosine kinase
VC395_A0826	ENOG4105E0M	Sulfatase
VC395_A0828	ENOG4105C1J	atp-dependent rna helicase
VC395_A0829	ENOG4108ENQ	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
VC395_A0831	ENOG4105CVA	phosphate
VC395_A0833	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
VC395_A0835	ENOG4108M1A	Chitin-binding protein
VC395_A0836	ENOG4105D4Y	metalloprotease
VC395_A0838	ENOG4105CYW	agmatinase
VC395_A0839	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
VC395_A0842	ENOG4105CJW	magnesium transporter
VC395_A0843	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
VC395_A0844	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
VC395_A0846	ENOG4105CZK	Aspartate kinase
VC395_A0847	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
VC395_A0848	ENOG4108JPW	Aminotransferase
VC395_A0849	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
VC395_A0851	ENOG41090A4	Pterin carbinolamine dehydratase
VC395_A0852	ENOG4105MIR	Phenylalanine 4-monooxygenase
VC395_A0853	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
VC395_A0856	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
VC395_A0857	ENOG4105EGI	Transcriptional regulator
VC395_A0860	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
VC395_A0861	ENOG4105C37	(CBS) domain
VC395_A0862	ENOG4108UKZ	OsmC family
VC395_A0864	ENOG4107YWA	deoxycytidylate deaminase
VC395_A0871	ENOG4105DVH	amino acid
VC395_A0874	ENOG4108VAC	response regulator
VC395_A0875	ENOG4108HRK	Histidine kinase
VC395_A0878	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
VC395_A0879	ENOG4105C19	ABC transporter
VC395_A0883	ENOG4107RGM	aldo keto reductase
VC395_A0884	ENOG4107T9C	Alpha amylase catalytic region
VC395_A0886	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
VC395_A0887	ENOG4108M0H	Extracellular lipase
VC395_A0888	ENOG4107SDU	Methyl-accepting chemotaxis
VC395_A0889	ENOG4105D4Y	metalloprotease
VC395_A0891	ENOG4105EIF	outer membrane protein W
VC395_A0894	ENOG41061WM	D-Alanyl-D-Alanine
VC395_A0895	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
VC395_A0896	ENOG4105C4M	(Ubiquinol oxidase) subunit I
VC395_A0897	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
VC395_A0899	ENOG4105BZC	d-serine deaminase
VC395_A0900	ENOG4105W8I	Transcriptional regulator
VC395_A0910	ENOG4105CPQ	Dehydrogenase
VC395_A0911	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
VC395_A0912	ENOG4105TMR	Functions as a holding molecular chaperone (holdase) which stabilizes unfolding intermediates and rapidly releases them in an active form once stress has abated. Plays an important role in protecting cells from severe heat shock and starvation, as well as in acid resistance of stationary-phase cells. It catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step (By similarity)
VC395_A0914	ENOG4105EXG	Transcriptional regulator
VC395_A0915	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
VC395_A0921	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
VC395_A0922	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
VC395_A0923	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
VC395_A0928	ENOG4105BZW	Glycerate kinase
VC395_A0929	ENOG4105C6Z	Gluconate
VC395_A0930	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
VC395_A0931	ENOG4108NVR	Methyl-accepting chemotaxis
VC395_A0932	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
VC395_A0933	ENOG41090JE	Utilization Protein
VC395_A0934	ENOG4105D4P	Coproporphyrinogen iii oxidase
VC395_A0935	ENOG4105WQ5	TonB family
VC395_A0936	ENOG41090AP	transport protein
VC395_A0937	ENOG4106GFD	transport protein
VC395_A0938	ENOG4107R4I	Periplasmic binding protein
VC395_A0939	ENOG4105EHG	Permease protein
VC395_A0940	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
VC395_A0948	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_A0949	ENOG4105QVC	MOSC domain-containing protein
VC395_A0949	ENOG4105QVC	MOSC domain-containing protein
VC395_A0950	ENOG4105EKE	dihydroorotase
VC395_A0952	ENOG4105KAF	membrAne
VC395_A0954	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
VC395_A0955	ENOG4105CKW	Inner membrane protein yedI
VC395_A0956	ENOG4108ESY	Metal dependent phosphohydrolase
VC395_A0958	ENOG4105VEQ	Cold shock protein
VC395_A0964	ENOG4105BZU	Histidine kinase
VC395_A0965	ENOG4105E98	transcriptional regulator DeoR family
VC395_A0968	ENOG4105EG2	ABC transporter, permease
VC395_A0969	ENOG4105D56	permease protein
VC395_A0970	ENOG4107FKK	extracellular solute-binding protein family 1
VC395_A0971	ENOG4108IJ9	(ABC) transporter
VC395_A0972	ENOG4108HK0	-acetyltransferase
VC395_A0976	ENOG4105K8R	UPF0145 protein
VC395_A0977	ENOG41086KC	Transcriptional regulator
VC395_A0978	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
VC395_A0979	ENOG4107R88	Chemotaxis protein (CheV)
VC395_A0980	ENOG4105K56	Transcriptional regulator
VC395_A0981	ENOG4106TD9	Diguanylate cyclase
VC395_A0985	ENOG4105BZU	Histidine kinase
VC395_A0989	ENOG4105ETT	transcriptional Regulator, LysR family
VC395_A0990	ENOG4108K0B	C-di-gmp phosphodiesterase
VC395_A0994	ENOG4105EUB	pirin domain protein
VC395_A0995	ENOG4105NBK	UPF0345 protein
VC395_A0997	ENOG4105E5W	Transporter
VC395_A0999	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_A1000	ENOG4105DAN	ATP-dependent protease
VC395_A1002	ENOG4108JQ5	ABC transporter
VC395_A1003	ENOG4105E89	ABC transporter
VC395_A1004	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_A1006	ENOG4105CC0	LysR family Transcriptional regulator
VC395_A1007	ENOG4105DAA	L-lactate
VC395_A1008	ENOG4105DMF	Dehydrogenase
VC395_A1010	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
VC395_A1012	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
VC395_A1014	ENOG4105C1J	atp-dependent rna helicase
VC395_A1015	ENOG4105CR8	Transcriptional regulator
VC395_A1017	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
VC395_A1020	ENOG4105BZ1	(ABC) transporter
VC395_A1022	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
VC395_A1029	ENOG4105K56	Transcriptional regulator
VC395_A1030	ENOG4108ZHJ	Organic hydroperoxide resistance protein
VC395_A1034	ENOG4108SXK	Transporter Drug Metabolite Exporter family
VC395_A1035	ENOG4105VW4	glutaredoxin 3
VC395_A1036	ENOG4108P2H	Inner membrane protein YjiG
VC395_A1037	ENOG41074DU	domain protein
VC395_A1039	ENOG4105DN9	Na H antiporter
VC395_A1041	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
VC395_A1042	ENOG4105D03	DNA-3-methyladenine glycosylase II
VC395_A1043	ENOG4108VGI	doxx family
VC395_A1048	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
VC395_A1050	ENOG4107W52	maltose operon periplasmic protein
VC395_A1051	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
VC395_A1054	ENOG4108N3W	hemolysin secretion protein
VC395_A1057	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_A1059	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
VC395_A1060	ENOG4105CDA	abc transporter atp-binding protein
VC395_A1062	ENOG4106TNF	Periplasmic binding protein
VC395_A1063	ENOG4105EZ7	amino acid ABC transporter
VC395_A1064	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
VC395_A1066	ENOG4105DR5	peptidase
VC395_A1068	ENOG4105CTS	PTS system mannitol-specific
VC395_A1069	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
VC395_A1070	ENOG4105E61	Mannitol repressor protein
VC395_A1071	ENOG4105EP9	oxidoreductase
VC395_A1077	ENOG4108RYK	Nad-dependent epimerase dehydratase
VC395_A1078	ENOG4105JQN	Transcriptional regulator
VC395_A1079	ENOG41069D7	Methyl-accepting chemotaxis
VC395_A1080	ENOG4105EMU	Dehydrogenase
VC395_A1081	ENOG4105JQN	Transcriptional regulator
VC395_A1083	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
VC395_A1084	ENOG4105D5Q	Arginine ornithine antiporter
VC395_A1085	ENOG4105CXN	decarboxylase
VC395_A1089	ENOG4107RGH	Aldehyde dehydrogenase
VC395_A1090	ENOG4105EW9	transcriptional regulator AsnC family
VC395_A1091	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_A1093	ENOG4105CK7	Sodium proline symporter
VC395_A1095	ENOG4105C26	Dehydrogenase
VC395_A1099	ENOG4105E6M	Sulphatase-modifying factor protein
VC395_A1101	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
VC395_A1102	ENOG4107QZV	Type I secretion membrane fusion protein
VC395_A1105	ENOG4108JJA	ABC, transporter
VC395_A1107	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
VC395_A1109	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_A1110	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
VC395_A1111	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
VC395_A1112	ENOG4105BZU	Histidine kinase
VC395_A1113	ENOG4105C8Q	Methyl-accepting chemotaxis
VC395_A1114	ENOG4108V3W	Chemotaxis protein, CheW
VC395_A1115	ENOG4108V3W	Chemotaxis protein, CheW
VC395_A1116	ENOG4105CBS	Chea signal transduction histidine kinase
VC395_A1117	ENOG4108VYJ	response regulator receiver protein
VC395_A1120	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
VC395_A1121	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
VC395_A1122	ENOG4108JQ6	ABC transporter
VC395_A1125	ENOG4105DHQ	Histidine kinase
VC395_A1126	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
VC395_A1132	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
VC395_A1133	ENOG4107RUE	extracellular solute-binding protein family 1
VC395_A1134	ENOG4106RMF	ParB family