locus-tag	class	description
LZM82_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LZM82_00010	COG0592	DNA-directed DNA polymerase activity
LZM82_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LZM82_00020	COG0187	DNA topoisomerase II activity
LZM82_00030	COG0071	Belongs to the small heat shock protein (HSP20) family
LZM82_00035	COG3977	Valine--pyruvate aminotransferase
LZM82_00040	COG0751	glycine-tRNA ligase activity
LZM82_00045	COG0752	glycyl-tRNA synthetase alpha subunit
LZM82_00050	COG2119	membrane
LZM82_00060	COG0425	Belongs to the sulfur carrier protein TusA family
LZM82_00070	COG0604	alcohol dehydrogenase
LZM82_00080	COG0129	dihydroxy-acid dehydratase activity
LZM82_00085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LZM82_00100	COG0606	chelatase, subunit chli
LZM82_00105	COG0204	Acyl-transferase
LZM82_00110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZM82_00115	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LZM82_00125	COG3084	Protein conserved in bacteria
LZM82_00130	COG4326	sporulation control protein
LZM82_00135	COG1272	protein, Hemolysin III
LZM82_00145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LZM82_00150	COG0569	domain protein
LZM82_00155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LZM82_00155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LZM82_00160	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LZM82_00165	COG0242	peptide deformylase activity
LZM82_00170	COG1652	LysM domain
LZM82_00175	COG0758	DNA mediated transformation
LZM82_00180	COG2922	Belongs to the Smg family
LZM82_00185	COG0551	DNA topoisomerase type I activity
LZM82_00190	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LZM82_00195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LZM82_00200	COG0009	L-threonylcarbamoyladenylate synthase
LZM82_00205	COG0408	coproporphyrinogen oxidase activity
LZM82_00210	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LZM82_00220	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LZM82_00260	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LZM82_00265	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LZM82_00275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LZM82_00280	COG2104	thiamine diphosphate biosynthetic process
LZM82_00285	COG2022	thiamine diphosphate biosynthetic process
LZM82_00290	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LZM82_00295	COG0006	proline dipeptidase activity
LZM82_00295	COG0006	proline dipeptidase activity
LZM82_00315	COG1522	sequence-specific DNA binding
LZM82_00320	COG5001	Diguanylate cyclase
LZM82_00320	COG5002	protein histidine kinase activity
LZM82_00340	COG0589	response to stress
LZM82_00345	COG1528	Iron-storage protein
LZM82_00355	COG2081	HI0933 family
LZM82_00365	COG1322	Protein conserved in bacteria
LZM82_00370	COG2226	methyltransferase
LZM82_00385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LZM82_00390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LZM82_00395	COG0805	protein transport
LZM82_00400	COG1858	cytochrome C peroxidase
LZM82_00405	COG0534	Mate efflux family protein
LZM82_00415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LZM82_00425	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LZM82_00430	COG3161	chorismate lyase activity
LZM82_00435	COG1580	Controls the rotational direction of flagella during chemotaxis
LZM82_00440	COG0840	transmembrane signaling receptor activity
LZM82_00450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LZM82_00455	COG0084	hydrolase, TatD family'
LZM82_00470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LZM82_00470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LZM82_00490	COG3078	GTPase activator activity
LZM82_00505	COG3071	HemY protein
LZM82_00510	COG2959	enzyme of heme biosynthesis
LZM82_00515	COG1587	Uroporphyrinogen-III synthase
LZM82_00520	COG0181	hydroxymethylbilane synthase activity
LZM82_00530	COG1965	Belongs to the frataxin family
LZM82_00540	COG0019	diaminopimelate decarboxylase activity
LZM82_00545	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LZM82_00555	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZM82_00560	COG1011	Hydrolase
LZM82_00565	COG2199	diguanylate cyclase activity
LZM82_00565	COG2200	EAL domain
LZM82_00565	COG3287	FIST C domain
LZM82_00580	COG0561	phosphatase activity
LZM82_00585	COG2267	carboxylic ester hydrolase activity
LZM82_00590	COG1280	lysine exporter protein (LysE YggA)
LZM82_00595	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LZM82_00600	COG0783	Belongs to the Dps family
LZM82_00630	COG0742	ribosomal rna small subunit methyltransferase
LZM82_00635	COG0552	protein localization to endoplasmic reticulum
LZM82_00640	COG2884	Cell division ATP-binding protein ftsE
LZM82_00645	COG2177	Part of the ABC transporter FtsEX involved in
LZM82_00650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LZM82_00655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZM82_00670	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LZM82_00675	COG4206	TonB-dependent receptor
LZM82_00680	COG1404	Belongs to the peptidase S8 family
LZM82_00685	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LZM82_00720	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LZM82_00725	COG5001	Diguanylate cyclase
LZM82_00725	COG3300	MHYT domain
LZM82_00735	COG3852	Histidine kinase
LZM82_00745	COG0174	glutamine synthetase
LZM82_00755	COG1217	gtp-binding protein TYPA
LZM82_00765	COG1295	ribonuclease BN
LZM82_00770	COG1490	D-aminoacyl-tRNA deacylase activity
LZM82_00775	COG0456	acetyltransferase
LZM82_00785	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LZM82_00790	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LZM82_00795	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LZM82_00800	COG3031	protein transport across the cell outer membrane
LZM82_00810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZM82_00815	COG1459	type II secretion system
LZM82_00820	COG2165	general secretion pathway protein
LZM82_00825	COG2165	general secretion pathway protein
LZM82_00830	COG2165	general secretion pathway protein
LZM82_00835	COG4795	General secretion pathway protein
LZM82_00840	COG3156	type II secretion system protein K
LZM82_00845	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
LZM82_00850	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
LZM82_00860	COG1218	3'(2'),5'-bisphosphate nucleotidase
LZM82_00865	COG0494	nUDIX hydrolase
LZM82_00875	COG1040	competence protein
LZM82_00885	COG0596	Alpha beta hydrolase
LZM82_00895	COG2183	response to ionizing radiation
LZM82_00900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LZM82_00915	COG2233	PERMEase
LZM82_00920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LZM82_00925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZM82_00930	COG1758	RNA polymerase activity
LZM82_00935	COG0194	GDP metabolic process
LZM82_00940	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LZM82_00945	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LZM82_00965	COG4232	protein-disulfide reductase activity
LZM82_00975	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LZM82_00980	COG1027	Aspartate ammonia-lyase
LZM82_00985	COG3706	GGDEF domain
LZM82_00990	COG3030	protein affecting phage T7 exclusion by the F plasmid
LZM82_00995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LZM82_01005	COG2205	protein histidine kinase activity
LZM82_01010	COG0745	RESPONSE REGULATOR receiver
LZM82_01020	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LZM82_01025	COG0205	6-phosphofructokinase activity
LZM82_01030	COG1494	fructose-1,6-bisphosphatase
LZM82_01035	COG3074	FtsZ-dependent cytokinesis
LZM82_01040	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LZM82_01045	COG0460	homoserine dehydrogenase
LZM82_01045	COG0527	aspartate kinase activity
LZM82_01050	COG0626	cystathionine gamma-synthase activity
LZM82_01055	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
LZM82_01060	COG0281	malic enzyme
LZM82_01065	COG0254	rRNA binding
LZM82_01070	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LZM82_01075	COG1609	Transcriptional regulator
LZM82_01080	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LZM82_01085	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LZM82_01090	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LZM82_01095	COG1575	Belongs to the MenA family. Type 1 subfamily
LZM82_01100	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LZM82_01105	COG0534	Mate efflux family protein
LZM82_01110	COG0149	triose-phosphate isomerase activity
LZM82_01135	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LZM82_01140	COG0459	protein refolding
LZM82_01150	COG1509	lysine 2,3-aminomutase activity
LZM82_01155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LZM82_01165	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LZM82_01170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LZM82_01175	COG1053	succinate dehydrogenase
LZM82_01180	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LZM82_01185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LZM82_01190	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LZM82_01195	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LZM82_01200	COG1045	serine acetyltransferase
LZM82_01210	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LZM82_01215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LZM82_01220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LZM82_01225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LZM82_01230	COG0137	argininosuccinate synthase activity
LZM82_01235	COG0165	Argininosuccinate lyase
LZM82_01245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZM82_01250	COG0678	peroxiredoxin activity
LZM82_01250	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LZM82_01260	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LZM82_01290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LZM82_01295	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LZM82_01305	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LZM82_01310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LZM82_01315	COG0546	phosphoglycolate phosphatase activity
LZM82_01320	COG0180	Tryptophanyl-tRNA synthetase
LZM82_01335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LZM82_01345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LZM82_01355	COG1012	belongs to the aldehyde dehydrogenase family
LZM82_01370	COG3954	Phosphoribulokinase
LZM82_01380	COG0429	hydrolase of the alpha beta-hydrolase fold
LZM82_01390	COG0488	(ABC) transporter
LZM82_01395	COG2249	NAD(P)H dehydrogenase (quinone) activity
LZM82_01410	COG1047	Peptidyl-prolyl cis-trans
LZM82_01425	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LZM82_01430	COG3083	sulfuric ester hydrolase activity
LZM82_01435	COG0557	exoribonuclease II activity
LZM82_01440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LZM82_01445	COG0051	transcription antitermination factor activity, RNA binding
LZM82_01450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LZM82_01455	COG0088	Forms part of the polypeptide exit tunnel
LZM82_01460	COG0089	rRNA binding
LZM82_01465	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LZM82_01470	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LZM82_01475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LZM82_01480	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LZM82_01485	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LZM82_01490	COG0255	Belongs to the universal ribosomal protein uL29 family
LZM82_01495	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LZM82_01500	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LZM82_01505	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LZM82_01510	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LZM82_01515	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LZM82_01520	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LZM82_01530	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LZM82_01535	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LZM82_01540	COG1841	ribosomal large subunit assembly
LZM82_01550	COG0201	protein transport
LZM82_01555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LZM82_01560	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LZM82_01565	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LZM82_01570	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LZM82_01575	COG0202	RNA polymerase activity
LZM82_01580	COG0203	ribosomal protein L17
LZM82_01590	COG0545	Peptidyl-prolyl cis-trans isomerase
LZM82_01595	COG3266	domain, Protein
LZM82_01595	COG3061	Opacity-associated protein A
LZM82_01600	COG0697	spore germination
LZM82_01605	COG2153	protein acetylation
LZM82_01610	COG0513	Belongs to the DEAD box helicase family
LZM82_01625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LZM82_01625	COG1648	precorrin-2 dehydrogenase activity
LZM82_01640	COG0529	Catalyzes the synthesis of activated sulfate
LZM82_01660	COG1136	(ABC) transporter
LZM82_01675	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LZM82_01680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LZM82_01685	COG0729	surface antigen
LZM82_01695	COG2105	PFAM AIG2 family protein
LZM82_01700	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LZM82_01710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LZM82_01715	COG0163	prenyltransferase activity
LZM82_01725	COG1178	ABC-type Fe3 transport system permease component
LZM82_01730	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
LZM82_01735	COG3028	Belongs to the UPF0307 family
LZM82_01740	COG0312	modulator of DNA gyrase
LZM82_01745	COG2239	Acts as a magnesium transporter
LZM82_01750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZM82_01755	COG1660	Displays ATPase and GTPase activities
LZM82_01760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZM82_01765	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LZM82_01775	COG1137	ATPase activity
LZM82_01780	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LZM82_01795	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LZM82_01795	COG0517	IMP dehydrogenase activity
LZM82_01805	COG1127	ABC transporter
LZM82_01810	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZM82_01815	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LZM82_01820	COG2854	intermembrane phospholipid transfer
LZM82_01830	COG5007	Belongs to the BolA IbaG family
LZM82_01835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LZM82_01845	COG0251	oxidation-reduction process
LZM82_01855	COG0540	Belongs to the ATCase OTCase family
LZM82_01865	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LZM82_01875	COG0564	pseudouridine synthase activity
LZM82_01880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LZM82_01885	COG0525	valine-tRNA ligase activity
LZM82_01890	COG2927	DNA polymerase III (CHI subunit)
LZM82_01895	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LZM82_01900	COG0795	lipopolysaccharide-transporting ATPase activity
LZM82_01905	COG0795	lipopolysaccharide-transporting ATPase activity
LZM82_01920	COG3437	response regulator, receiver
LZM82_01965	COG0066	3-isopropylmalate dehydratase activity
LZM82_01970	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LZM82_01975	COG0473	3-isopropylmalate dehydrogenase activity
LZM82_02000	COG0583	DNA-binding transcription factor activity
LZM82_02005	COG1022	Amp-dependent synthetase and ligase
LZM82_02010	COG0028	Belongs to the TPP enzyme family
LZM82_02015	COG0440	acetolactate synthase activity
LZM82_02020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LZM82_02025	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LZM82_02030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LZM82_02040	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LZM82_02045	COG3079	Belongs to the UPF0149 family
LZM82_02050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZM82_02055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZM82_02070	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LZM82_02080	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LZM82_02085	COG1595	DNA-templated transcription, initiation
LZM82_02100	COG3086	response to oxidative stress
LZM82_02105	COG0481	GTPase activity
LZM82_02120	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LZM82_02125	COG1381	Involved in DNA repair and RecF pathway recombination
LZM82_02130	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LZM82_02150	COG5001	Diguanylate cyclase
LZM82_02165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZM82_02170	COG3956	TIGRFAM MazG family protein
LZM82_02175	COG0504	CTP synthase activity
LZM82_02180	COG0148	phosphopyruvate hydratase activity
LZM82_02190	COG3409	Peptidoglycan-binding domain 1 protein
LZM82_02190	COG3267	Type II secretory pathway component ExeA
LZM82_02200	COG4991	sh3 domain protein
LZM82_02205	COG0306	phosphate transporter
LZM82_02210	COG1392	Phosphate transport regulator
LZM82_02215	COG3025	triphosphatase activity
LZM82_02220	COG0840	transmembrane signaling receptor activity
LZM82_02225	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LZM82_02235	COG1538	Outer membrane efflux protein
LZM82_02240	COG0494	nUDIX hydrolase
LZM82_02245	COG3151	Protein conserved in bacteria
LZM82_02255	COG3150	esterase
LZM82_02260	COG0187	DNA topoisomerase II activity
LZM82_02265	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LZM82_02275	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
LZM82_02280	COG0237	dephospho-CoA kinase activity
LZM82_02290	COG1459	type II secretion system
LZM82_02295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZM82_02315	COG0716	FMN binding
LZM82_02320	COG4974	Belongs to the 'phage' integrase family
LZM82_02325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZM82_02330	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LZM82_02335	COG0737	Belongs to the 5'-nucleotidase family
LZM82_02340	COG2186	Transcriptional regulator
LZM82_02345	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LZM82_02350	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZM82_02355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZM82_02370	COG3116	cell division
LZM82_02375	COG0768	penicillin binding
LZM82_02380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LZM82_02385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LZM82_02395	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LZM82_02400	COG0772	Belongs to the SEDS family
LZM82_02410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LZM82_02415	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LZM82_02420	COG0849	cell division
LZM82_02425	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LZM82_02430	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LZM82_02440	COG0653	protein targeting
LZM82_02445	COG0494	nUDIX hydrolase
LZM82_02450	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LZM82_02460	COG0505	Belongs to the CarA family
LZM82_02465	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LZM82_02480	COG4172	Belongs to the ABC transporter superfamily
LZM82_02490	COG0730	response to heat
LZM82_02495	COG0583	DNA-binding transcription factor activity
LZM82_02500	COG2860	membrane
LZM82_02505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LZM82_02515	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LZM82_02525	COG0493	'glutamate synthase
LZM82_02530	COG0067	glutamate synthase
LZM82_02530	COG0069	glutamate synthase activity
LZM82_02530	COG0070	glutamate synthase
LZM82_02540	COG0070	glutamate synthase
LZM82_02540	COG0067	glutamate synthase
LZM82_02540	COG0069	glutamate synthase activity
LZM82_02545	COG1242	4 iron, 4 sulfur cluster binding
LZM82_02550	COG2203	Gaf domain
LZM82_02550	COG3706	GGDEF domain
LZM82_02550	COG4251	negative regulation of phosphorylation
LZM82_02550	COG5001	Diguanylate cyclase
LZM82_02555	COG5002	protein histidine kinase activity
LZM82_02555	COG0784	Response regulator, receiver
LZM82_02555	COG2198	Histidine kinase
LZM82_02560	COG0745	RESPONSE REGULATOR receiver
LZM82_02570	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LZM82_02595	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LZM82_02600	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LZM82_02605	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LZM82_02610	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LZM82_02625	COG1115	amino acid carrier protein
LZM82_02630	COG3022	response to hydroperoxide
LZM82_02640	COG0084	hydrolase, TatD family'
LZM82_02645	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LZM82_02655	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LZM82_02660	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LZM82_02665	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LZM82_02670	COG0813	purine-nucleoside phosphorylase activity
LZM82_02680	COG0560	Phosphoserine phosphatase
LZM82_02690	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LZM82_02695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LZM82_02700	COG1022	Amp-dependent synthetase and ligase
LZM82_02730	COG1609	Transcriptional regulator
LZM82_02735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LZM82_02750	COG0569	domain protein
LZM82_02750	COG0189	ligase activity
LZM82_02755	COG0456	acetyltransferase
LZM82_02765	COG2171	N-acyltransferase activity
LZM82_02770	COG3141	response to X-ray
LZM82_02785	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LZM82_02790	COG1074	ATP-dependent DNA helicase activity
LZM82_02795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZM82_02805	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LZM82_02805	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LZM82_02815	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LZM82_02820	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LZM82_02825	COG2166	iron-sulfur cluster assembly
LZM82_02830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LZM82_02835	COG0693	protein deglycase activity
LZM82_02840	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LZM82_02845	COG3248	Nucleoside-binding outer membrane protein
LZM82_02855	COG1595	DNA-templated transcription, initiation
LZM82_02865	COG2211	Major facilitator Superfamily
LZM82_02870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LZM82_02880	COG2813	Specifically methylates the guanine in position
LZM82_02885	COG0271	Belongs to the BolA IbaG family
LZM82_02890	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LZM82_02895	COG1805	sodium ion transport
LZM82_02900	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LZM82_02905	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LZM82_02910	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LZM82_02915	COG2871	sodium ion transport
LZM82_02920	COG1477	protein flavinylation
LZM82_02950	COG3328	transposase activity
LZM82_02955	COG3706	GGDEF domain
LZM82_02960	COG0733	neurotransmitter:sodium symporter activity
LZM82_02970	COG0189	ligase activity
LZM82_02975	COG0189	ligase activity
LZM82_02975	COG4067	protein conserved in archaea
LZM82_02980	COG2195	Cleaves the N-terminal amino acid of tripeptides
LZM82_02985	COG2252	PERMEase
LZM82_02990	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LZM82_02995	COG1073	alpha beta
LZM82_03005	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LZM82_03010	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LZM82_03015	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LZM82_03020	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZM82_03020	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZM82_03035	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LZM82_03040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LZM82_03045	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LZM82_03050	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LZM82_03060	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LZM82_03065	COG0024	Methionine aminopeptidase
LZM82_03070	COG0052	Belongs to the universal ribosomal protein uS2 family
LZM82_03075	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LZM82_03080	COG0528	UMP kinase activity
LZM82_03085	COG0233	cytoplasmic translational termination
LZM82_03090	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LZM82_03095	COG0575	Belongs to the CDS family
LZM82_03100	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LZM82_03105	COG0750	zinc metalloprotease
LZM82_03115	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LZM82_03120	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZM82_03125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LZM82_03130	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZM82_03135	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZM82_03140	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LZM82_03145	COG0587	DNA-directed DNA polymerase activity
LZM82_03150	COG0825	malonyl-CoA metabolic process
LZM82_03155	COG0037	tRNA processing
LZM82_03165	COG3479	Phenolic acid decarboxylase
LZM82_03170	COG0347	Belongs to the P(II) protein family
LZM82_03175	COG3021	interspecies interaction between organisms
LZM82_03180	COG1388	LysM domain
LZM82_03180	COG0741	lytic transglycosylase activity
LZM82_03185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZM82_03190	COG2226	methyltransferase
LZM82_03195	COG0328	RNA-DNA hybrid ribonuclease activity
LZM82_03210	COG1960	acyl-CoA dehydrogenase activity
LZM82_03215	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LZM82_03220	COG0121	glutamine amidotransferase
LZM82_03225	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LZM82_03230	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LZM82_03235	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LZM82_03245	COG1187	pseudouridine synthase activity
LZM82_03250	COG2840	Smr protein MutS2
LZM82_03265	COG3735	TraB family
LZM82_03280	COG2217	Heavy metal translocating P-type atpase
LZM82_03280	COG2608	mercury ion transmembrane transporter activity
LZM82_03285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LZM82_03305	COG4774	siderophore transport
LZM82_03305	COG1629	transport
LZM82_03310	COG2375	cellular response to nickel ion
LZM82_03315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LZM82_03315	COG2226	methyltransferase
LZM82_03315	COG3433	isochorismatase activity
LZM82_03350	COG0835	chemotaxis
LZM82_03350	COG0784	Response regulator, receiver
LZM82_03355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LZM82_03360	COG1815	bacterial-type flagellum-dependent cell motility
LZM82_03375	COG1749	Flagellar hook protein flgE
LZM82_03380	COG4787	bacterial-type flagellum-dependent cell motility
LZM82_03390	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LZM82_03395	COG1706	bacterial-type flagellum-dependent cell motility
LZM82_03400	COG1705	Flagellar rod assembly protein muramidase FlgJ
LZM82_03400	COG3951	Flagellar rod assembly protein muramidase FlgJ
LZM82_03500	COG0012	GTP binding
LZM82_03505	COG0193	aminoacyl-tRNA hydrolase activity
LZM82_03510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LZM82_03515	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LZM82_03520	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LZM82_03525	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LZM82_03530	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LZM82_03535	COG2890	protein-(glutamine-N5) methyltransferase activity
LZM82_03545	COG2912	Transglutaminase-like superfamily
LZM82_03550	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LZM82_03555	COG0737	Belongs to the 5'-nucleotidase family
LZM82_03560	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LZM82_03565	COG2233	PERMEase
LZM82_03585	COG1393	Belongs to the ArsC family
LZM82_03590	COG4783	chaperone-mediated protein folding
LZM82_03605	COG0840	transmembrane signaling receptor activity
LZM82_03610	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LZM82_03625	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LZM82_03635	COG1876	peptidase activity
LZM82_03645	COG1393	Belongs to the ArsC family
LZM82_03665	COG2837	iron assimilation
LZM82_03670	COG1334	flagellar protein FlaG
LZM82_03675	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LZM82_03685	COG1516	flagellar protein fliS
LZM82_03705	COG1677	Flagellar hook-basal body complex protein FliE
LZM82_03715	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LZM82_03720	COG1317	bacterial-type flagellum organization
LZM82_03745	COG1580	Controls the rotational direction of flagella during chemotaxis
LZM82_03770	COG1987	bacterial-type flagellum assembly
LZM82_03775	COG1684	flagellar biosynthetic protein fliR
LZM82_03785	COG2840	Smr protein MutS2
LZM82_03790	COG2890	protein-(glutamine-N5) methyltransferase activity
LZM82_03795	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LZM82_03800	COG2860	membrane
LZM82_03805	COG3101	peptidyl-lysine hydroxylation
LZM82_03815	COG0431	NADPH-dependent FMN reductase
LZM82_03825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LZM82_03830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LZM82_03835	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LZM82_03840	COG0735	belongs to the Fur family
LZM82_03850	COG0583	DNA-binding transcription factor activity
LZM82_03860	COG1346	cytolysis
LZM82_03875	COG0596	Alpha beta hydrolase
LZM82_03880	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LZM82_03885	COG0033	Phosphoglucomutase
LZM82_03895	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LZM82_03900	COG0372	Belongs to the citrate synthase family
LZM82_03905	COG2009	succinate dehydrogenase
LZM82_03910	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LZM82_03915	COG1053	succinate dehydrogenase
LZM82_03925	COG0567	Dehydrogenase, E1 component
LZM82_03930	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZM82_03935	COG0045	succinate-CoA ligase (ADP-forming) activity
LZM82_03945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LZM82_03950	COG1121	(ABC) transporter
LZM82_03955	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LZM82_03960	COG4977	sequence-specific DNA binding
LZM82_03965	COG1918	ferrous iron import across plasma membrane
LZM82_03985	COG0018	arginyl-trna synthetase
LZM82_03995	COG1025	Belongs to the peptidase M16 family
LZM82_04000	COG2062	phosphohistidine phosphatase, SixA
LZM82_04030	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LZM82_04035	COG0643	Histidine kinase
LZM82_04035	COG2198	Histidine kinase
LZM82_04035	COG0784	Response regulator, receiver
LZM82_04040	COG2201	protein-glutamate methylesterase activity
LZM82_04045	COG1192	Involved in chromosome partitioning
LZM82_04055	COG0835	chemotaxis
LZM82_04065	COG4133	protoheme IX ABC transporter activity
LZM82_04070	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LZM82_04075	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LZM82_04085	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LZM82_04090	COG1138	Cytochrome C-type biogenesis protein
LZM82_04095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZM82_04100	COG4235	cytochrome complex assembly
LZM82_04100	COG3088	subunit of a heme lyase
LZM82_04110	COG2853	Lipoprotein
LZM82_04130	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZM82_04135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LZM82_04140	COG0123	including yeast histone deacetylase and acetoin utilization protein
LZM82_04155	COG3083	sulfuric ester hydrolase activity
LZM82_04160	COG3082	Protein of unknown function (DUF1414)
LZM82_04165	COG3081	Nucleoid-associated protein
LZM82_04175	COG1757	Na H antiporter
LZM82_04180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LZM82_04185	COG2095	MarC family integral membrane protein
LZM82_04190	COG1454	alcohol dehydrogenase
LZM82_04190	COG1012	belongs to the aldehyde dehydrogenase family
LZM82_04200	COG0659	secondary active sulfate transmembrane transporter activity
LZM82_04205	COG1530	ribonuclease E activity
LZM82_04210	COG0564	pseudouridine synthase activity
LZM82_04215	COG0424	maF-like protein
LZM82_04220	COG1399	metal-binding, possibly nucleic acid-binding protein
LZM82_04225	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LZM82_04230	COG0416	fatty acid biosynthetic process
LZM82_04235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZM82_04245	COG1028	Short-chain dehydrogenase reductase Sdr
LZM82_04250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LZM82_04255	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LZM82_04260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LZM82_04265	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LZM82_04270	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LZM82_04280	COG0084	hydrolase, TatD family'
LZM82_04285	COG1263	PTS System
LZM82_04285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LZM82_04295	COG0733	neurotransmitter:sodium symporter activity
LZM82_04310	COG4667	esterase of the alpha-beta hydrolase superfamily
LZM82_04320	COG1940	carbohydrate kinase activity
LZM82_04325	COG0835	chemotaxis
LZM82_04325	COG0784	Response regulator, receiver
LZM82_04340	COG2226	methyltransferase
LZM82_04350	COG0676	glucose-6-phosphate 1-epimerase activity
LZM82_04355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LZM82_04360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LZM82_04370	COG3139	Protein of unknown function (DUF1315)
LZM82_04375	COG0252	asparaginase activity
LZM82_04380	COG0616	signal peptide processing
LZM82_04385	COG0446	pyridine nucleotide-disulphide oxidoreductase
LZM82_04385	COG1902	pentaerythritol trinitrate reductase activity
LZM82_04390	COG0788	formyltetrahydrofolate deformylase activity
LZM82_04400	COG1199	ATP-dependent helicase activity
LZM82_04405	COG1214	PFAM Peptidase M22, glycoprotease
LZM82_04420	COG0596	Alpha beta hydrolase
LZM82_04425	COG0318	PFAM AMP-dependent synthetase and ligase
LZM82_04430	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LZM82_04450	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LZM82_04455	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LZM82_04460	COG0436	Aminotransferase
LZM82_04465	COG1169	isochorismate synthase
LZM82_04470	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LZM82_04475	COG0596	Alpha beta hydrolase
LZM82_04495	COG3135	benzoate transporter
LZM82_04500	COG1396	sequence-specific DNA binding
LZM82_04505	COG0840	transmembrane signaling receptor activity
LZM82_04515	COG0477	Major facilitator Superfamily
LZM82_04535	COG3015	lipoprotein NlpE involved in copper resistance
LZM82_04540	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LZM82_04545	COG2894	cell division
LZM82_04550	COG0850	regulation of cytokinetic process
LZM82_04555	COG3100	YcgL domain-containing protein
LZM82_04560	COG2951	lytic endotransglycosylase activity
LZM82_04570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LZM82_04575	COG3469	chitinase activity
LZM82_04575	COG3325	Belongs to the glycosyl hydrolase 18 family
LZM82_04580	COG3005	denitrification pathway
LZM82_04585	COG0243	molybdopterin cofactor binding
LZM82_04600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZM82_04610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LZM82_04645	COG4589	Belongs to the CDS family
LZM82_04655	COG3300	MHYT domain
LZM82_04655	COG5001	Diguanylate cyclase
LZM82_04665	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LZM82_04670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LZM82_04675	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LZM82_04680	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LZM82_04690	COG4191	Histidine kinase
LZM82_04700	COG0544	peptidyl-prolyl cis-trans isomerase activity
LZM82_04710	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LZM82_04715	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LZM82_04720	COG0776	regulation of translation
LZM82_04725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LZM82_04730	COG1555	photosystem II stabilization
LZM82_04735	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LZM82_04740	COG0539	negative regulation of cytoplasmic translation
LZM82_04745	COG0776	regulation of translation
LZM82_04750	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LZM82_04755	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LZM82_04775	COG0583	DNA-binding transcription factor activity
LZM82_04785	COG0686	Belongs to the AlaDH PNT family
LZM82_04795	COG1674	ftsk spoiiie
LZM82_04800	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LZM82_04805	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LZM82_04810	COG2186	Transcriptional regulator
LZM82_04825	COG0537	adenosine 5'-monophosphoramidase activity
LZM82_04850	COG3150	esterase
LZM82_04855	COG1252	NADH dehydrogenase
LZM82_04875	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LZM82_04885	COG4591	ABC-type transport system involved in lipoprotein release permease component
LZM82_04890	COG1136	(ABC) transporter
LZM82_04895	COG4591	ABC-type transport system involved in lipoprotein release permease component
LZM82_04905	COG0658	competence protein
LZM82_04905	COG2333	competence protein COMEC
LZM82_04910	COG1132	(ABC) transporter
LZM82_04915	COG1663	tetraacyldisaccharide 4'-kinase activity
LZM82_04920	COG2835	tetraacyldisaccharide 4'-kinase activity
LZM82_04925	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LZM82_04930	COG2719	SpoVR family
LZM82_04935	COG2718	Belongs to the UPF0229 family
LZM82_04940	COG2766	serine protein kinase
LZM82_04945	COG3013	Belongs to the UPF0304 family
LZM82_04955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LZM82_04960	COG0840	transmembrane signaling receptor activity
LZM82_04970	COG1882	Formate acetyltransferase
LZM82_04995	COG4160	amino acid transport
LZM82_05000	COG0708	Exodeoxyribonuclease III
LZM82_05005	COG0840	transmembrane signaling receptor activity
LZM82_05015	COG3923	Primosomal replication protein n
LZM82_05020	COG0730	response to heat
LZM82_05025	COG1199	ATP-dependent helicase activity
LZM82_05030	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LZM82_05035	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LZM82_05040	COG3012	SEC-C Motif Domain Protein
LZM82_05045	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LZM82_05050	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZM82_05055	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LZM82_05060	COG0215	cysteine-tRNA ligase activity
LZM82_05065	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LZM82_05070	COG0632	four-way junction helicase activity
LZM82_05080	COG1271	oxidase subunit
LZM82_05085	COG1294	oxidase, subunit
LZM82_05090	COG4890	Cyd operon protein YbgT
LZM82_05100	COG0824	Thioesterase
LZM82_05105	COG0811	peptide transport
LZM82_05120	COG0823	Involved in the tonB-independent uptake of proteins
LZM82_05125	COG2885	chlorophyll binding
LZM82_05135	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LZM82_05145	COG0784	Response regulator, receiver
LZM82_05145	COG5002	protein histidine kinase activity
LZM82_05155	COG1482	cell wall glycoprotein biosynthetic process
LZM82_05160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LZM82_05160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZM82_05160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LZM82_05165	COG2207	Transcriptional regulator
LZM82_05175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LZM82_05180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LZM82_05185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LZM82_05195	COG1012	belongs to the aldehyde dehydrogenase family
LZM82_05200	COG3284	Transcriptional regulator
LZM82_05205	COG4628	conserved protein (DUF2132)
LZM82_05215	COG0415	Belongs to the DNA photolyase family
LZM82_05300	COG0488	(ABC) transporter
LZM82_05340	COG3941	tape measure
LZM82_05360	COG2003	Belongs to the UPF0758 family
LZM82_05370	COG4409	exo-alpha-(2->6)-sialidase activity
LZM82_05375	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LZM82_05380	COG1940	carbohydrate kinase activity
LZM82_05390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LZM82_05395	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LZM82_05400	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LZM82_05405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LZM82_05410	COG1737	Transcriptional regulator
LZM82_05415	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
LZM82_05420	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
LZM82_05440	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LZM82_05460	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LZM82_05480	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LZM82_05485	COG0582	viral genome integration into host DNA
LZM82_05490	COG0582	viral genome integration into host DNA
LZM82_05505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZM82_05515	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LZM82_05515	COG3008	intermembrane lipid transfer
LZM82_05520	COG2995	paraquat-inducible protein a
LZM82_05525	COG0668	transmembrane transport
LZM82_05545	COG1309	transcriptional regulator
LZM82_05550	COG1012	belongs to the aldehyde dehydrogenase family
LZM82_05580	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LZM82_05585	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LZM82_05610	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LZM82_05615	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LZM82_05620	COG0297	glycogen (starch) synthase activity
LZM82_05640	COG3070	regulator of competence-specific genes
LZM82_05645	COG1609	Transcriptional regulator
LZM82_05650	COG3381	protein complex oligomerization
LZM82_05655	COG0745	RESPONSE REGULATOR receiver
LZM82_05660	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LZM82_05665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LZM82_05675	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
LZM82_05695	COG1032	radical SAM domain protein
LZM82_05700	COG5001	Diguanylate cyclase
LZM82_05705	COG0612	Peptidase, M16
LZM82_05720	COG0583	DNA-binding transcription factor activity
LZM82_05725	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LZM82_05735	COG2350	Protein conserved in bacteria
LZM82_05740	COG1607	acyl-coa hydrolase
LZM82_05755	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LZM82_05760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZM82_05770	COG2116	formate transmembrane transporter activity
LZM82_05780	COG4459	periplasmic nitrate reductase
LZM82_05785	COG3005	denitrification pathway
LZM82_05790	COG0243	molybdopterin cofactor binding
LZM82_05810	COG1227	inorganic diphosphatase activity
LZM82_05825	COG4172	Belongs to the ABC transporter superfamily
LZM82_05840	COG4168	peptide transport system, permease
LZM82_05850	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LZM82_05855	COG1842	Phage shock protein A
LZM82_05870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZM82_05885	COG2818	Glycosylase
LZM82_05890	COG0626	cystathionine gamma-synthase activity
LZM82_05900	COG0733	neurotransmitter:sodium symporter activity
LZM82_05905	COG0564	pseudouridine synthase activity
LZM82_05910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LZM82_05915	COG4136	ATPase activity
LZM82_05920	COG4135	transport system, permease component
LZM82_05925	COG4134	Bacterial extracellular solute-binding protein
LZM82_05935	COG3313	Fe-S protein
LZM82_05945	COG0842	Transport permease protein
LZM82_05950	COG1131	(ABC) transporter
LZM82_05955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZM82_05960	COG0814	amino acid
LZM82_05970	COG2239	Acts as a magnesium transporter
LZM82_05975	COG0784	Response regulator, receiver
LZM82_05975	COG2205	protein histidine kinase activity
LZM82_05990	COG4934	collagen metabolic process
LZM82_06020	COG0840	transmembrane signaling receptor activity
LZM82_06030	COG5001	Diguanylate cyclase
LZM82_06030	COG2203	Gaf domain
LZM82_06030	COG4251	negative regulation of phosphorylation
LZM82_06030	COG3706	GGDEF domain
LZM82_06035	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LZM82_06055	COG1061	Type III restriction enzyme res subunit
LZM82_06060	COG1187	pseudouridine synthase activity
LZM82_06065	COG2814	Major facilitator Superfamily
LZM82_06075	COG0702	epimerase
LZM82_06080	COG0534	Mate efflux family protein
LZM82_06085	COG4181	ATPase activity
LZM82_06090	COG0577	efflux transmembrane transporter activity
LZM82_06100	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LZM82_06110	COG1748	Saccharopine dehydrogenase
LZM82_06125	COG1538	Outer membrane efflux protein
LZM82_06150	COG0583	DNA-binding transcription factor activity
LZM82_06160	COG1451	nucleotide metabolic process
LZM82_06165	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LZM82_06175	COG3063	Type IV pilus biogenesis stability protein PilW
LZM82_06180	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LZM82_06200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZM82_06215	COG3290	protein histidine kinase activity
LZM82_06220	COG4565	transcriptional regulatory protein
LZM82_06230	COG0835	chemotaxis
LZM82_06230	COG0784	Response regulator, receiver
LZM82_06275	COG1085	galactose-1-phosphate uridylyltransferase
LZM82_06280	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LZM82_06285	COG2017	converts alpha-aldose to the beta-anomer
LZM82_06295	COG2200	EAL domain
LZM82_06295	COG2199	diguanylate cyclase activity
LZM82_06325	COG0753	catalase activity
LZM82_06345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LZM82_06355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LZM82_06395	COG1271	oxidase subunit
LZM82_06400	COG1294	oxidase, subunit
LZM82_06405	COG4591	ABC-type transport system involved in lipoprotein release permease component
LZM82_06405	COG1136	(ABC) transporter
LZM82_06410	COG0577	efflux transmembrane transporter activity
LZM82_06410	COG1136	(ABC) transporter
LZM82_06415	COG0577	efflux transmembrane transporter activity
LZM82_06415	COG1136	(ABC) transporter
LZM82_06435	COG0583	DNA-binding transcription factor activity
LZM82_06445	COG2723	6-phospho-beta-galactosidase activity
LZM82_06450	COG1609	Transcriptional regulator
LZM82_06455	COG0251	oxidation-reduction process
LZM82_06460	COG2731	YhcH YjgK YiaL family protein
LZM82_06465	COG0584	glycerophosphoryl diester phosphodiesterase
LZM82_06470	COG1349	DNA-binding transcription factor activity
LZM82_06475	COG3842	ATPase activity
LZM82_06480	COG0395	ABC-type sugar transport system, permease component
LZM82_06485	COG1175	transmembrane transport
LZM82_06500	COG0811	peptide transport
LZM82_06505	COG0811	peptide transport
LZM82_06510	COG0848	biopolymer transport protein
LZM82_06515	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LZM82_06525	COG1793	dna ligase
LZM82_06535	COG0534	Mate efflux family protein
LZM82_06545	COG3001	Fructosamine kinase
LZM82_06555	COG0791	NLP P60 protein
LZM82_06560	COG0840	transmembrane signaling receptor activity
LZM82_06570	COG3148	PFAM DTW domain containing protein
LZM82_06575	COG1940	carbohydrate kinase activity
LZM82_06600	COG0746	molybdenum cofactor guanylyltransferase activity
LZM82_06605	COG3842	ATPase activity
LZM82_06610	COG4662	Binding-protein-dependent transport system inner membrane component
LZM82_06620	COG2204	response regulator
LZM82_06625	COG3852	Histidine kinase
LZM82_06630	COG0488	(ABC) transporter
LZM82_06635	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LZM82_06665	COG3383	formate dehydrogenase (NAD+) activity
LZM82_06665	COG0243	molybdopterin cofactor binding
LZM82_06670	COG0437	4 iron, 4 sulfur cluster binding
LZM82_06685	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LZM82_06690	COG1666	GTP binding
LZM82_06695	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LZM82_06710	COG2996	Protein conserved in bacteria
LZM82_06720	COG3008	intermembrane lipid transfer
LZM82_06725	COG2995	paraquat-inducible protein a
LZM82_06730	COG1132	(ABC) transporter
LZM82_06735	COG1956	GAF domain-containing protein
LZM82_06740	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
LZM82_06755	COG0308	aminopeptidase N
LZM82_06770	COG0167	dihydroorotate dehydrogenase activity
LZM82_06780	COG0116	Belongs to the methyltransferase superfamily
LZM82_06780	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LZM82_06790	COG0488	(ABC) transporter
LZM82_06805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LZM82_06810	COG1067	ATP-dependent peptidase activity
LZM82_06815	COG3120	sequence-specific DNA binding
LZM82_06830	COG0784	Response regulator, receiver
LZM82_06830	COG2205	protein histidine kinase activity
LZM82_06845	COG3278	Belongs to the heme-copper respiratory oxidase family
LZM82_06860	COG2010	Cytochrome c
LZM82_06870	COG2217	Heavy metal translocating P-type atpase
LZM82_06885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZM82_06890	COG0589	response to stress
LZM82_06915	COG3842	ATPase activity
LZM82_06925	COG1177	transmembrane transport
LZM82_06935	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LZM82_06950	COG1115	amino acid carrier protein
LZM82_06955	COG1280	lysine exporter protein (LysE YggA)
LZM82_06970	COG3675	Pfam Lipase (class 3)
LZM82_06980	COG3501	Rhs element vgr protein
LZM82_06990	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LZM82_07000	COG2814	Major facilitator Superfamily
LZM82_07005	COG1566	PFAM secretion protein HlyD family protein
LZM82_07010	COG1538	Outer membrane efflux protein
LZM82_07020	COG0513	Belongs to the DEAD box helicase family
LZM82_07025	COG0840	transmembrane signaling receptor activity
LZM82_07035	COG0840	transmembrane signaling receptor activity
LZM82_07040	COG3290	protein histidine kinase activity
LZM82_07040	COG0840	transmembrane signaling receptor activity
LZM82_07045	COG0835	chemotaxis
LZM82_07050	COG2201	protein-glutamate methylesterase activity
LZM82_07060	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LZM82_07065	COG2198	Histidine kinase
LZM82_07065	COG0784	Response regulator, receiver
LZM82_07065	COG0643	Histidine kinase
LZM82_07070	COG2198	Histidine kinase
LZM82_07070	COG0643	Histidine kinase
LZM82_07080	COG0745	RESPONSE REGULATOR receiver
LZM82_07095	COG0415	Belongs to the DNA photolyase family
LZM82_07100	COG0477	Major facilitator Superfamily
LZM82_07105	COG0583	DNA-binding transcription factor activity
LZM82_07115	COG0095	Lipoate-protein ligase
LZM82_07120	COG0443	Heat shock 70 kDa protein
LZM82_07130	COG1643	Atp-dependent helicase
LZM82_07160	COG0443	Heat shock 70 kDa protein
LZM82_07165	COG0443	Heat shock 70 kDa protein
LZM82_07170	COG3706	GGDEF domain
LZM82_07200	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LZM82_07205	COG0602	queuosine metabolic process
LZM82_07210	COG0561	phosphatase activity
LZM82_07220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LZM82_07225	COG4597	amino acid ABC transporter
LZM82_07230	COG0765	amino acid transport
LZM82_07235	COG1126	abc transporter atp-binding protein
LZM82_07240	COG0670	Belongs to the BI1 family
LZM82_07245	COG2920	part of a sulfur-relay system
LZM82_07250	COG1254	Belongs to the acylphosphatase family
LZM82_07255	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LZM82_07260	COG3706	GGDEF domain
LZM82_07275	COG3437	response regulator, receiver
LZM82_07280	COG0625	glutathione transferase activity
LZM82_07290	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LZM82_07300	COG2195	Cleaves the N-terminal amino acid of tripeptides
LZM82_07330	COG0372	Belongs to the citrate synthase family
LZM82_07335	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LZM82_07375	COG1129	ABC transporter
LZM82_07400	COG0745	RESPONSE REGULATOR receiver
LZM82_07405	COG2205	protein histidine kinase activity
LZM82_07410	COG3713	MltA-interacting MipA family protein
LZM82_07415	COG2990	Protein conserved in bacteria
LZM82_07425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LZM82_07425	COG4191	Histidine kinase
LZM82_07430	COG0471	metal ion transport
LZM82_07440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LZM82_07455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LZM82_07465	COG3768	UPF0283 membrane protein
LZM82_07470	COG3106	COG3106 Predicted ATPase
LZM82_07485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LZM82_07490	COG0494	nUDIX hydrolase
LZM82_07495	COG0814	amino acid
LZM82_07500	COG1760	l-serine dehydratase
LZM82_07505	COG0720	synthase
LZM82_07515	COG0017	Asparaginyl-tRNA synthetase
LZM82_07520	COG0351	phosphomethylpyrimidine kinase
LZM82_07525	COG3437	response regulator, receiver
LZM82_07525	COG2770	Histidine kinase
LZM82_07530	COG1448	Aminotransferase
LZM82_07545	COG0840	transmembrane signaling receptor activity
LZM82_07550	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LZM82_07555	COG2943	transferase activity, transferring hexosyl groups
LZM82_07560	COG1609	Transcriptional regulator
LZM82_07570	COG1486	melibiose metabolic process
LZM82_07575	COG1447	Phosphotransferase system cellobiose-specific component IIA
LZM82_07585	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LZM82_07590	COG0726	polysaccharide deacetylase
LZM82_07595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LZM82_07600	COG1846	Transcriptional regulator
LZM82_07625	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LZM82_07640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZM82_07645	COG3108	Peptidase M15
LZM82_07650	COG2989	Protein conserved in bacteria
LZM82_07675	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LZM82_07685	COG2814	Major facilitator Superfamily
LZM82_07695	COG1054	Belongs to the UPF0176 family
LZM82_07705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LZM82_07710	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZM82_07715	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZM82_07765	COG4139	cobalamin transport
LZM82_07785	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LZM82_07790	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LZM82_07795	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LZM82_07800	COG1823	symporter activity
LZM82_07805	COG2925	Exonuclease
LZM82_07810	COG1380	Effector of murein hydrolase LrgA
LZM82_07815	COG1346	cytolysis
LZM82_07845	COG0776	regulation of translation
LZM82_07850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LZM82_07850	COG0072	phenylalanine-tRNA ligase activity
LZM82_07855	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LZM82_07895	COG0322	excinuclease ABC activity
LZM82_07900	COG2197	response regulator
LZM82_07905	COG0417	DNA replication proofreading
LZM82_07910	COG5001	Diguanylate cyclase
LZM82_07920	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LZM82_07925	COG3099	Belongs to the UPF0263 family
LZM82_07940	COG1228	amidohydrolase
LZM82_07945	COG0010	Belongs to the arginase family
LZM82_07950	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LZM82_07955	COG2986	histidine ammonia-lyase
LZM82_07975	COG0277	FAD linked oxidase domain protein
LZM82_07975	COG0247	lactate metabolic process
LZM82_07990	COG2885	chlorophyll binding
LZM82_08010	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LZM82_08020	COG0281	malic enzyme
LZM82_08030	COG2949	membrane
LZM82_08035	COG3706	GGDEF domain
LZM82_08040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LZM82_08050	COG0492	ferredoxin-NADP+ reductase activity
LZM82_08055	COG4988	ABC transporter
LZM82_08060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LZM82_08065	COG1187	pseudouridine synthase activity
LZM82_08070	COG0009	L-threonylcarbamoyladenylate synthase
LZM82_08075	COG0613	PHP domain protein
LZM82_08085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LZM82_08090	COG0512	Glutamine amidotransferase of anthranilate synthase
LZM82_08095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LZM82_08100	COG0134	indole-3-glycerol-phosphate synthase activity
LZM82_08100	COG0135	phosphoribosylanthranilate isomerase activity
LZM82_08105	COG0133	tryptophan synthase activity
LZM82_08110	COG0159	tryptophan synthase activity
LZM82_08120	COG1435	thymidine kinase activity
LZM82_08125	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LZM82_08130	COG1801	Protein of unknown function DUF72
LZM82_08135	COG4106	trans-aconitate 2-methyltransferase activity
LZM82_08140	COG0500	methyltransferase
LZM82_08145	COG0189	ligase activity
LZM82_08145	COG4067	protein conserved in archaea
LZM82_08160	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LZM82_08170	COG3852	Histidine kinase
LZM82_08185	COG3070	regulator of competence-specific genes
LZM82_08195	COG2431	L-lysine efflux transmembrane transporter activity
LZM82_08205	COG0076	glutamate decarboxylase activity
LZM82_08210	COG1737	Transcriptional regulator
LZM82_08215	COG1012	belongs to the aldehyde dehydrogenase family
LZM82_08215	COG1454	alcohol dehydrogenase
LZM82_08220	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LZM82_08225	COG2985	domain, Protein
LZM82_08225	COG3273	potassium ion transport
LZM82_08230	COG0542	response to heat
LZM82_08235	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LZM82_08240	COG1278	Cold shock
LZM82_08250	COG1187	pseudouridine synthase activity
LZM82_08255	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LZM82_08255	COG0140	phosphoribosyl-ATP diphosphatase activity
LZM82_08260	COG0107	imidazoleglycerol-phosphate synthase activity
LZM82_08265	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LZM82_08270	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LZM82_08275	COG0131	Imidazoleglycerol-phosphate dehydratase
LZM82_08275	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LZM82_08280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LZM82_08285	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LZM82_08290	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LZM82_08295	COG1757	Na H antiporter
LZM82_08300	COG2916	Histone family protein nucleoid-structuring protein H-NS
LZM82_08305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZM82_08310	COG0482	sulfurtransferase activity
LZM82_08315	COG2915	High frequency lysogenization protein hflD homolog
LZM82_08320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LZM82_08330	COG2268	Band 7 protein
LZM82_08340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LZM82_08355	COG0300	oxidoreductase activity
LZM82_08365	COG0501	Belongs to the peptidase M48B family
LZM82_08375	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LZM82_08380	COG2226	methyltransferase
LZM82_08385	COG0156	8-amino-7-oxononanoate synthase activity
LZM82_08390	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LZM82_08395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LZM82_08400	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LZM82_08405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LZM82_08410	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LZM82_08420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LZM82_08425	COG2199	diguanylate cyclase activity
LZM82_08425	COG2203	Gaf domain
LZM82_08435	COG4120	Belongs to the binding-protein-dependent transport system permease family
LZM82_08445	COG4628	conserved protein (DUF2132)
LZM82_08450	COG3092	negative regulation of chromosome organization
LZM82_08455	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LZM82_08460	COG0857	belongs to the CobB CobQ family
LZM82_08460	COG0280	phosphate acetyltransferase
LZM82_08465	COG0435	Glutathione S-transferase
LZM82_08470	COG4608	Belongs to the ABC transporter superfamily
LZM82_08475	COG0444	Belongs to the ABC transporter superfamily
LZM82_08480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LZM82_08485	COG0601	transmembrane transport
LZM82_08505	COG2204	response regulator
LZM82_08510	COG3300	MHYT domain
LZM82_08510	COG5001	Diguanylate cyclase
LZM82_08515	COG4191	Histidine kinase
LZM82_08520	COG5002	protein histidine kinase activity
LZM82_08530	COG2201	protein-glutamate methylesterase activity
LZM82_08545	COG0009	L-threonylcarbamoyladenylate synthase
LZM82_08560	COG1881	PFAM PEBP family protein
LZM82_08585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LZM82_08590	COG0640	Transcriptional regulator
LZM82_08600	COG3706	GGDEF domain
LZM82_08620	COG1946	Acyl-CoA thioesterase
LZM82_08625	COG1522	sequence-specific DNA binding
LZM82_08635	COG0616	signal peptide processing
LZM82_08640	COG1028	Short-chain dehydrogenase reductase Sdr
LZM82_08645	COG2983	Belongs to the UPF0260 family
LZM82_08655	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LZM82_08660	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LZM82_08670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LZM82_08675	COG2832	Protein of unknown function (DUF454)
LZM82_08680	COG0745	RESPONSE REGULATOR receiver
LZM82_08685	COG0583	DNA-binding transcription factor activity
LZM82_08690	COG0778	Nitroreductase
LZM82_08695	COG1250	3-hydroxyacyl-CoA dehydrogenase
LZM82_08695	COG1024	Enoyl-CoA hydratase
LZM82_08700	COG0183	Belongs to the thiolase family
LZM82_08715	COG2067	long-chain fatty acid transport protein
LZM82_08725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LZM82_08730	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
LZM82_08735	COG2982	Protein involved in outer membrane biogenesis
LZM82_08740	COG0572	uridine kinase
LZM82_08745	COG0489	protein tyrosine kinase activity
LZM82_08750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LZM82_08750	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LZM82_08760	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
LZM82_08770	COG0517	IMP dehydrogenase activity
LZM82_08770	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LZM82_08770	COG0617	tRNA 3'-terminal CCA addition
LZM82_08775	COG2199	diguanylate cyclase activity
LZM82_08780	COG0314	molybdopterin synthase activity
LZM82_08785	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LZM82_08790	COG0315	cyclic pyranopterin monophosphate synthase activity
LZM82_08795	COG0521	Mo-molybdopterin cofactor biosynthetic process
LZM82_08800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LZM82_08805	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LZM82_08810	COG2198	Histidine kinase
LZM82_08815	COG2204	response regulator
LZM82_08820	COG0556	nucleotide-excision repair
LZM82_08830	COG4657	Part of a membrane complex involved in electron transport
LZM82_08835	COG2878	Part of a membrane complex involved in electron transport
LZM82_08840	COG4656	Part of a membrane complex involved in electron transport
LZM82_08860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LZM82_08865	COG0346	lactoylglutathione lyase activity
LZM82_08880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LZM82_08885	COG2056	Na+-H+ antiporter family
LZM82_08890	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LZM82_08895	COG1286	toxin biosynthetic process
LZM82_08900	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LZM82_08905	COG0285	dihydrofolate synthase activity
LZM82_08910	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LZM82_08915	COG0101	tRNA pseudouridine synthase activity
LZM82_08935	COG1263	PTS System
LZM82_08935	COG2190	(PTS) system
LZM82_08935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LZM82_08940	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LZM82_08945	COG1940	carbohydrate kinase activity
LZM82_08945	COG1846	Transcriptional regulator
LZM82_08950	COG4651	solute:proton antiporter activity
LZM82_08950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LZM82_08955	COG0367	asparagine synthase
LZM82_08970	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LZM82_08975	COG0563	adenylate kinase activity
LZM82_08980	COG0326	Molecular chaperone. Has ATPase activity
LZM82_08985	COG3710	Transcriptional regulator
LZM82_09000	COG0622	Phosphoesterase
LZM82_09005	COG1090	epimerase
LZM82_09010	COG0300	oxidoreductase activity
LZM82_09015	COG3118	belongs to the thioredoxin family
LZM82_09020	COG0330	HflC and HflK could
LZM82_09025	COG1585	Membrane protein implicated in regulation of membrane protease activity
LZM82_09030	COG0789	Transcriptional regulator
LZM82_09045	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LZM82_09050	COG3115	cell septum assembly
LZM82_09055	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LZM82_09060	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LZM82_09065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZM82_09075	COG2190	(PTS) system
LZM82_09080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZM82_09085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LZM82_09090	COG1702	phosphate starvation-inducible protein PhoH
LZM82_09100	COG4535	Mg2 and Co2 transporter CorC
LZM82_09105	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LZM82_09110	COG2888	peptidyl-tyrosine sulfation
LZM82_09115	COG0495	leucyl-tRNA aminoacylation
LZM82_09120	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
LZM82_09125	COG1466	dna polymerase III delta subunit
LZM82_09130	COG0799	negative regulation of ribosome biogenesis
LZM82_09135	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LZM82_09140	COG0768	penicillin binding
LZM82_09145	COG0772	Belongs to the SEDS family
LZM82_09150	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LZM82_09155	COG1686	Belongs to the peptidase S11 family
LZM82_09160	COG2921	Belongs to the UPF0250 family
LZM82_09165	COG0321	lipoyl(octanoyl) transferase activity
LZM82_09170	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LZM82_09180	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LZM82_09205	COG1596	polysaccharide export
LZM82_09215	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LZM82_09245	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LZM82_09255	COG0438	transferase activity, transferring glycosyl groups
LZM82_09265	COG1045	serine acetyltransferase
LZM82_09285	COG0110	maltose O-acetyltransferase activity
LZM82_09290	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LZM82_09295	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LZM82_09300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LZM82_09305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZM82_09335	COG0366	Alpha amylase catalytic
LZM82_09340	COG1263	PTS System
LZM82_09340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LZM82_09345	COG1609	Transcriptional regulator
LZM82_09350	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LZM82_09355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LZM82_09360	COG2011	ABC-type metal ion transport system permease component
LZM82_09365	COG1464	Belongs to the NlpA lipoprotein family
LZM82_09370	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
LZM82_09380	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LZM82_09380	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LZM82_09395	COG1611	Belongs to the LOG family
LZM82_09400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LZM82_09405	COG2363	Small membrane protein
LZM82_09410	COG0583	DNA-binding transcription factor activity
LZM82_09415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LZM82_09415	COG0301	tRNA thio-modification
LZM82_09425	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LZM82_09435	COG1722	exodeoxyribonuclease VII activity
LZM82_09440	COG0142	geranyltranstransferase activity
LZM82_09445	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LZM82_09450	COG0564	pseudouridine synthase activity
LZM82_09455	COG3098	single-species biofilm formation
LZM82_09470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LZM82_09480	COG1671	Belongs to the UPF0178 family
LZM82_09485	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LZM82_09490	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LZM82_09495	COG0254	rRNA binding
LZM82_09500	COG1720	tRNA m6t6A37 methyltransferase activity
LZM82_09505	COG0442	prolyl-tRNA aminoacylation
LZM82_09530	COG0047	phosphoribosylformylglycinamidine synthase activity
LZM82_09530	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LZM82_09540	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LZM82_09550	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LZM82_09580	COG0484	heat shock protein binding
LZM82_09585	COG0443	Heat shock 70 kDa protein
LZM82_09595	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LZM82_09600	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LZM82_09605	COG0497	DNA recombination
LZM82_09610	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZM82_09615	COG2914	Belongs to the UPF0125 (RnfH) family
LZM82_09620	COG2867	negative regulation of translational initiation
LZM82_09625	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LZM82_09635	COG0582	viral genome integration into host DNA
LZM82_09645	COG3064	Membrane
LZM82_09655	COG0739	heme binding
LZM82_09670	COG0840	transmembrane signaling receptor activity
LZM82_09675	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LZM82_09680	COG2207	Transcriptional regulator
LZM82_09690	COG1459	type II secretion system
LZM82_09695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZM82_09715	COG4796	Type ii and iii secretion system protein
LZM82_09730	COG2165	general secretion pathway protein
LZM82_09740	COG3710	Transcriptional regulator
LZM82_09745	COG0840	transmembrane signaling receptor activity
LZM82_09750	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LZM82_09770	COG1012	belongs to the aldehyde dehydrogenase family
LZM82_09825	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
LZM82_09830	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LZM82_09835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LZM82_09855	COG3051	citrate lyase alpha subunit
LZM82_09860	COG2301	Belongs to the HpcH HpaI aldolase family
LZM82_09870	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LZM82_09880	COG3630	sodium ion export across plasma membrane
LZM82_09885	COG0511	ligase activity, forming carbon-carbon bonds
LZM82_09885	COG5016	pyruvate
LZM82_09890	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
LZM82_09900	COG4565	transcriptional regulatory protein
LZM82_09915	COG0583	DNA-binding transcription factor activity
LZM82_09925	COG1115	amino acid carrier protein
LZM82_09930	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LZM82_09935	COG0583	DNA-binding transcription factor activity
LZM82_09945	COG1120	ATPase activity
LZM82_09950	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LZM82_09955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LZM82_09960	COG4592	Periplasmic binding protein
LZM82_09970	COG1028	Short-chain dehydrogenase reductase Sdr
LZM82_09975	COG1169	isochorismate synthase
LZM82_09980	COG1021	2,3-dihydroxybenzoate-AMP ligase
LZM82_09985	COG1535	isochorismatase
LZM82_09985	COG3433	isochorismatase activity
LZM82_09990	COG1584	GPR1 FUN34 yaaH family protein
LZM82_10000	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LZM82_10000	COG0519	Catalyzes the synthesis of GMP from XMP
LZM82_10005	COG0516	GMP reductase activity
LZM82_10005	COG0517	IMP dehydrogenase activity
LZM82_10010	COG1570	exodeoxyribonuclease VII activity
LZM82_10025	COG1160	GTP binding
LZM82_10030	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZM82_10035	COG2976	Protein conserved in bacteria
LZM82_10040	COG0124	histidyl-tRNA synthetase
LZM82_10045	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LZM82_10055	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LZM82_10060	COG0105	UTP biosynthetic process
LZM82_10065	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LZM82_10070	COG2975	iron-sulfur cluster assembly
LZM82_10075	COG0633	Ferredoxin
LZM82_10080	COG0443	Heat shock 70 kDa protein
LZM82_10085	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LZM82_10095	COG0822	iron-sulfur transferase activity
LZM82_10100	COG1104	cysteine desulfurase activity
LZM82_10105	COG1959	2 iron, 2 sulfur cluster binding
LZM82_10115	COG0483	inositol monophosphate 1-phosphatase activity
LZM82_10120	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZM82_10125	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZM82_10130	COG1862	Preprotein translocase
LZM82_10145	COG0517	IMP dehydrogenase activity
LZM82_10155	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LZM82_10160	COG0583	DNA-binding transcription factor activity
LZM82_10165	COG0450	alkyl hydroperoxide reductase
LZM82_10170	COG3142	Participates in the control of copper homeostasis
LZM82_10185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LZM82_10190	COG0581	inorganic phosphate transmembrane transporter activity
LZM82_10200	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LZM82_10205	COG0248	Ppx GppA phosphatase
LZM82_10215	COG5002	protein histidine kinase activity
LZM82_10220	COG0745	RESPONSE REGULATOR receiver
LZM82_10230	COG0826	peptidase U32
LZM82_10235	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LZM82_10275	COG0542	response to heat
LZM82_10285	COG0564	pseudouridine synthase activity
LZM82_10290	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZM82_10295	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LZM82_10300	COG0077	Prephenate dehydratase
LZM82_10300	COG1605	Chorismate mutase
LZM82_10305	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LZM82_10310	COG5001	Diguanylate cyclase
LZM82_10320	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LZM82_10330	COG0488	(ABC) transporter
LZM82_10340	COG0287	Prephenate dehydrogenase
LZM82_10340	COG1605	Chorismate mutase
LZM82_10345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LZM82_10350	COG3275	phosphorelay sensor kinase activity
LZM82_10355	COG3279	Response regulator of the LytR AlgR family
LZM82_10365	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LZM82_10370	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LZM82_10385	COG1966	Carbon starvation protein
LZM82_10390	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LZM82_10395	COG1047	Peptidyl-prolyl cis-trans
LZM82_10410	COG0196	riboflavin kinase activity
LZM82_10415	COG0728	peptidoglycan biosynthetic process
LZM82_10420	COG0268	Binds directly to 16S ribosomal RNA
LZM82_10425	COG0640	Transcriptional regulator
LZM82_10430	COG0583	DNA-binding transcription factor activity
LZM82_10435	COG1283	sodium-dependent phosphate transmembrane transporter activity
LZM82_10445	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LZM82_10450	COG0730	response to heat
LZM82_10455	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
LZM82_10460	COG0494	nUDIX hydrolase
LZM82_10470	COG0667	Aldo Keto reductase
LZM82_10480	COG2204	response regulator
LZM82_10485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LZM82_10505	COG0513	Belongs to the DEAD box helicase family
LZM82_10590	COG2003	Belongs to the UPF0758 family
LZM82_10615	COG0714	Associated with various cellular activities
LZM82_10635	COG0629	single-stranded DNA binding
LZM82_10650	COG2356	endonuclease I
LZM82_10690	COG0681	Belongs to the peptidase S26 family
LZM82_10705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZM82_10835	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LZM82_10850	COG3328	transposase activity
LZM82_10855	COG3328	transposase activity
LZM82_10920	COG3153	acetyltransferase
LZM82_10925	COG3154	lipid carrier protein
LZM82_10935	COG0826	peptidase U32
LZM82_10940	COG0826	peptidase U32
LZM82_10965	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LZM82_10975	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LZM82_10980	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LZM82_10985	COG0195	Participates in both transcription termination and antitermination
LZM82_10990	COG0779	Required for maturation of 30S ribosomal subunits
LZM82_11005	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LZM82_11015	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LZM82_11020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LZM82_11025	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LZM82_11030	COG1534	Rna-binding protein
LZM82_11035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LZM82_11040	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LZM82_11045	COG2027	D-alanyl-D-alanine carboxypeptidase
LZM82_11050	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LZM82_11055	COG0739	heme binding
LZM82_11070	COG0316	Belongs to the HesB IscA family
LZM82_11075	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LZM82_11080	COG0628	permease
LZM82_11085	COG2813	Specifically methylates the guanine in position
LZM82_11090	COG0784	Response regulator, receiver
LZM82_11090	COG2205	protein histidine kinase activity
LZM82_11095	COG0747	negative chemotaxis
LZM82_11100	COG0601	transmembrane transport
LZM82_11105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LZM82_11110	COG0444	Belongs to the ABC transporter superfamily
LZM82_11115	COG4608	Belongs to the ABC transporter superfamily
LZM82_11125	COG2971	BadF BadG BcrA BcrD
LZM82_11155	COG3842	ATPase activity
LZM82_11165	COG1840	ABC-type Fe3 transport system, periplasmic component
LZM82_11170	COG0004	ammonium transporteR
LZM82_11175	COG0347	Belongs to the P(II) protein family
LZM82_11180	COG3112	Uncharacterised protein family (UPF0231)
LZM82_11185	COG1049	propionate catabolic process, 2-methylcitrate cycle
LZM82_11190	COG1752	Esterase of the alpha-beta hydrolase superfamily
LZM82_11195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LZM82_11200	COG1643	Atp-dependent helicase
LZM82_11210	COG1489	DNA binding
LZM82_11220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LZM82_11230	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LZM82_11235	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LZM82_11240	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LZM82_11245	COG0842	Transport permease protein
LZM82_11250	COG1131	(ABC) transporter
LZM82_11255	COG0659	secondary active sulfate transmembrane transporter activity
LZM82_11260	COG0288	reversible hydration of carbon dioxide
LZM82_11275	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LZM82_11280	COG3107	peptidoglycan biosynthetic process
LZM82_11285	COG0792	nuclease activity
LZM82_11290	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LZM82_11295	COG2823	Periplasmic or secreted lipoprotein
LZM82_11300	COG2969	positive regulation of protein catabolic process
LZM82_11305	COG0625	glutathione transferase activity
LZM82_11310	COG2857	Cytochrome c1
LZM82_11315	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LZM82_11320	COG0723	plastoquinol--plastocyanin reductase activity
LZM82_11325	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LZM82_11330	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LZM82_11335	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LZM82_11345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZM82_11350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZM82_11355	COG0335	large ribosomal subunit rRNA binding
LZM82_11360	COG0336	Belongs to the RNA methyltransferase TrmD family
LZM82_11365	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LZM82_11370	COG0228	four-way junction DNA binding
LZM82_11375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LZM82_11380	COG4137	Cytochrome C assembly protein
LZM82_11385	COG4536	flavin adenine dinucleotide binding
LZM82_11390	COG1854	S-ribosylhomocysteine lyase activity
LZM82_11395	COG2918	glutathione biosynthetic process
LZM82_11400	COG0612	Peptidase, M16
LZM82_11405	COG1238	metal cluster binding
LZM82_11415	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
LZM82_11420	COG5016	pyruvate
LZM82_11420	COG0511	ligase activity, forming carbon-carbon bonds
LZM82_11425	COG3630	sodium ion export across plasma membrane
LZM82_11470	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LZM82_11475	COG0527	aspartate kinase activity
LZM82_11480	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LZM82_11495	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LZM82_11500	COG4208	sulfate ABC transporter
LZM82_11520	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LZM82_11525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LZM82_11535	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LZM82_11540	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LZM82_11545	COG0585	pseudouridine synthase activity
LZM82_11550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LZM82_11555	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LZM82_11560	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LZM82_11565	COG1968	undecaprenyl-diphosphatase activity
LZM82_11570	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LZM82_11575	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LZM82_11580	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LZM82_11590	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LZM82_11595	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LZM82_11600	COG1610	YqeY-like protein
LZM82_11605	COG0358	DNA primase activity
LZM82_11620	COG0582	viral genome integration into host DNA
LZM82_11625	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LZM82_11630	COG0840	transmembrane signaling receptor activity
LZM82_11635	COG2207	Transcriptional regulator
LZM82_11680	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LZM82_11685	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LZM82_11690	COG1349	DNA-binding transcription factor activity
LZM82_11710	COG1279	arginine transmembrane transporter activity
LZM82_11715	COG0668	transmembrane transport
LZM82_11720	COG0191	fructose-bisphosphate aldolase activity
LZM82_11725	COG0126	phosphoglycerate kinase activity
LZM82_11730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LZM82_11735	COG4771	TonB-dependent receptor
LZM82_11740	COG0583	DNA-binding transcription factor activity
LZM82_11745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LZM82_11750	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LZM82_11760	COG2356	endonuclease I
LZM82_11765	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LZM82_11770	COG0189	ligase activity
LZM82_11775	COG1678	Uncharacterized ACR, COG1678
LZM82_11780	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LZM82_11785	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LZM82_11805	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LZM82_11810	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LZM82_11815	COG0762	integral membrane protein
LZM82_11820	COG1872	DUF167
LZM82_11830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LZM82_11835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LZM82_11840	COG2066	Belongs to the glutaminase family
LZM82_11850	COG1194	a g-specific adenine glycosylase
LZM82_11855	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LZM82_11860	COG0741	lytic transglycosylase activity
LZM82_11915	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LZM82_11920	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LZM82_11925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LZM82_11930	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LZM82_11935	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LZM82_11940	COG2967	ApaG domain
LZM82_11945	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LZM82_11955	COG3610	response to peptide
LZM82_11960	COG2966	Psort location CytoplasmicMembrane, score
LZM82_11965	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LZM82_11970	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LZM82_11975	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LZM82_11980	COG0142	geranyltranstransferase activity
LZM82_11990	COG0039	L-malate dehydrogenase activity
LZM82_11995	COG1438	arginine binding
LZM82_12000	COG2358	TRAP transporter, solute receptor (TAXI family
LZM82_12010	COG0589	response to stress
LZM82_12030	COG2235	arginine
LZM82_12035	COG0312	modulator of DNA gyrase
LZM82_12040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LZM82_12045	COG3164	Protein of unknown function
LZM82_12055	COG0424	maF-like protein
LZM82_12060	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LZM82_12065	COG1792	Involved in formation and maintenance of cell shape
LZM82_12070	COG1077	Cell shape determining protein MreB Mrl
LZM82_12100	COG2165	general secretion pathway protein
LZM82_12105	COG2165	general secretion pathway protein
LZM82_12115	COG1459	type II secretion system
LZM82_12120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZM82_12130	COG3267	Type II secretory pathway component ExeA
LZM82_12130	COG3409	Peptidoglycan-binding domain 1 protein
LZM82_12155	COG2200	EAL domain
LZM82_12155	COG2199	diguanylate cyclase activity
LZM82_12160	COG0629	single-stranded DNA binding
LZM82_12175	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LZM82_12185	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LZM82_12190	COG0527	aspartate kinase activity
LZM82_12195	COG0646	methionine synthase
LZM82_12195	COG1410	methionine synthase
LZM82_12290	COG0175	sulfate reduction
LZM82_12300	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LZM82_12325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LZM82_12330	COG0735	belongs to the Fur family
LZM82_12350	COG0432	Pfam Uncharacterised protein family UPF0047
LZM82_12355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LZM82_12370	COG0359	binds to the 23S rRNA
LZM82_12375	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LZM82_12380	COG2965	DNA replication, synthesis of RNA primer
LZM82_12385	COG0360	Binds together with S18 to 16S ribosomal RNA
LZM82_12395	COG2906	2 iron, 2 sulfur cluster binding
LZM82_12400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LZM82_12405	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LZM82_12410	COG0049	tRNA binding
LZM82_12415	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LZM82_12425	COG2923	Belongs to the DsrF TusC family
LZM82_12430	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LZM82_12435	COG2964	Protein conserved in bacteria
LZM82_12440	COG0545	Peptidyl-prolyl cis-trans isomerase
LZM82_12450	COG2900	Belongs to the SlyX family
LZM82_12455	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LZM82_12460	COG0330	HflC and HflK could
LZM82_12465	COG0330	HflC and HflK could
LZM82_12470	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LZM82_12475	COG1923	regulation of RNA biosynthetic process
LZM82_12480	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LZM82_12485	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LZM82_12495	COG0802	atpase or kinase
LZM82_12500	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LZM82_12545	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LZM82_12550	COG1162	GTPase activity
LZM82_12555	COG0688	phosphatidylethanolamine metabolic process
LZM82_12560	COG0471	metal ion transport
LZM82_12570	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LZM82_12575	COG4942	peptidase
LZM82_12590	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LZM82_12595	COG2816	NAD+ diphosphatase activity
LZM82_12600	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LZM82_12605	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LZM82_12610	COG0085	RNA polymerase activity
LZM82_12615	COG0222	ribosome binding
LZM82_12620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LZM82_12630	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LZM82_12635	COG0250	Participates in transcription elongation, termination and antitermination
LZM82_12640	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LZM82_12645	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LZM82_12670	COG1072	(Pantothenic acid kinase))
LZM82_12680	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LZM82_12690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZM82_12735	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LZM82_12750	COG3118	belongs to the thioredoxin family
LZM82_12755	COG0513	Belongs to the DEAD box helicase family
LZM82_12760	COG0248	Ppx GppA phosphatase
LZM82_12765	COG0784	Response regulator, receiver
LZM82_12765	COG2205	protein histidine kinase activity
LZM82_12770	COG2814	Major facilitator Superfamily
LZM82_12785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LZM82_12790	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LZM82_12795	COG0511	ligase activity, forming carbon-carbon bonds
LZM82_12800	COG0439	Biotin carboxylase
LZM82_12805	COG2264	protein methyltransferase activity
LZM82_12810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LZM82_12815	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LZM82_12820	COG1609	Transcriptional regulator
LZM82_12825	COG0129	dihydroxy-acid dehydratase activity
LZM82_12830	COG3265	gluconokinase activity
LZM82_12840	COG0800	Aldolase
LZM82_12865	COG0840	transmembrane signaling receptor activity
LZM82_12870	COG1982	Orn Lys Arg decarboxylase major
LZM82_12875	COG0531	amino acid
LZM82_12880	COG3710	Transcriptional regulator
LZM82_12885	COG0789	Transcriptional regulator
LZM82_12900	COG0151	Belongs to the GarS family
LZM82_12910	COG0776	regulation of translation
LZM82_12915	COG1253	flavin adenine dinucleotide binding
LZM82_12920	COG1940	carbohydrate kinase activity
LZM82_12930	COG3068	Protein conserved in bacteria
LZM82_12940	COG1573	uracil-dna glycosylase
LZM82_12945	COG0668	transmembrane transport
LZM82_12950	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LZM82_12955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LZM82_13000	COG1012	belongs to the aldehyde dehydrogenase family
LZM82_13000	COG1454	alcohol dehydrogenase
LZM82_13005	COG0318	PFAM AMP-dependent synthetase and ligase
LZM82_13035	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LZM82_13040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZM82_13045	COG0662	Cupin 2, conserved barrel domain protein
LZM82_13045	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LZM82_13050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZM82_13085	COG1519	Transferase
LZM82_13115	COG3642	lipopolysaccharide core region biosynthetic process
LZM82_13120	COG0859	PFAM glycosyl transferase family 9
LZM82_13125	COG0463	Glycosyl transferase, family 2
LZM82_13130	COG0859	PFAM glycosyl transferase family 9
LZM82_13135	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LZM82_13140	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LZM82_13150	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LZM82_13155	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LZM82_13160	COG2003	Belongs to the UPF0758 family
LZM82_13170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LZM82_13180	COG1309	transcriptional regulator
LZM82_13185	COG1560	Kdo2-lipid A biosynthetic process
LZM82_13190	COG1560	Kdo2-lipid A biosynthetic process
LZM82_13195	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LZM82_13200	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LZM82_13205	COG1561	YicC-like family, N-terminal region
LZM82_13210	COG2862	Uncharacterized protein family, UPF0114
LZM82_13215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LZM82_13215	COG1263	PTS System
LZM82_13220	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LZM82_13240	COG1120	ATPase activity
LZM82_13245	COG4774	siderophore transport
LZM82_13250	COG1132	(ABC) transporter
LZM82_13265	COG0514	ATP-dependent DNA helicase (RecQ)
LZM82_13270	COG2962	Rard protein
LZM82_13285	COG1280	lysine exporter protein (LysE YggA)
LZM82_13290	COG0210	DNA helicase
LZM82_13300	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LZM82_13305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZM82_13345	COG3621	Patatin-like phospholipase
LZM82_13370	COG2131	deaminase
LZM82_13380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LZM82_13385	COG0601	transmembrane transport
LZM82_13390	COG0747	negative chemotaxis
LZM82_13440	COG1309	transcriptional regulator
LZM82_13445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZM82_13450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZM82_13455	COG2960	long-chain fatty acid transporting porin activity
LZM82_13460	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LZM82_13465	COG0583	DNA-binding transcription factor activity
LZM82_13510	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LZM82_13515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LZM82_13520	COG1739	Uncharacterized protein family UPF0029
LZM82_13530	COG0183	Belongs to the thiolase family
LZM82_13535	COG0583	DNA-binding transcription factor activity
LZM82_13540	COG2814	Major facilitator Superfamily
LZM82_13545	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LZM82_13550	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LZM82_13555	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LZM82_13560	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LZM82_13565	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LZM82_13570	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LZM82_13575	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LZM82_13585	COG0356	it plays a direct role in the translocation of protons across the membrane
LZM82_13590	COG3312	ion transport
LZM82_13595	COG1475	DNA binding
LZM82_13600	COG1192	Involved in chromosome partitioning
LZM82_13610	COG0445	tRNA wobble uridine modification
LZM82_13615	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LZM82_13620	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LZM82_13625	COG0706	membrane insertase activity
LZM82_13635	COG0594	ribonuclease P activity
LZM82_13640	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LZM82_13645	COG1126	abc transporter atp-binding protein
LZM82_13665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LZM82_13680	COG0840	transmembrane signaling receptor activity
LZM82_13685	COG0714	Associated with various cellular activities
LZM82_13705	COG2304	oxidoreductase activity
LZM82_13720	COG1278	Cold shock
LZM82_13725	COG5002	protein histidine kinase activity
LZM82_13725	COG5001	Diguanylate cyclase
LZM82_13735	COG3530	Putative quorum-sensing-regulated virulence factor
LZM82_13745	COG0814	amino acid
LZM82_13750	COG0589	response to stress
LZM82_13760	COG2111	Na H antiporter
LZM82_13760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LZM82_13765	COG1006	Multisubunit Na H antiporter MnhC subunit
LZM82_13770	COG0651	ATP synthesis coupled electron transport
LZM82_13775	COG1863	multisubunit Na H antiporter MnhE subunit
LZM82_13780	COG2212	antiporter activity
LZM82_13785	COG1320	monovalent cation:proton antiporter activity
LZM82_13795	COG0242	peptide deformylase activity
LZM82_13805	COG0579	oxidoreductase
LZM82_13840	COG2271	Major facilitator Superfamily
LZM82_13845	COG0584	glycerophosphoryl diester phosphodiesterase
LZM82_13855	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
LZM82_13865	COG1609	Transcriptional regulator
LZM82_13870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZM82_13875	COG1879	ABC-type sugar transport system periplasmic component
LZM82_13880	COG1172	Belongs to the binding-protein-dependent transport system permease family
LZM82_13885	COG1129	ABC transporter
LZM82_13890	COG1869	D-ribose catabolic process
LZM82_13905	COG3501	Rhs element vgr protein
LZM82_13905	COG3409	Peptidoglycan-binding domain 1 protein
LZM82_13930	COG3829	transcription factor binding
LZM82_13995	COG0564	pseudouridine synthase activity
LZM82_14005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LZM82_14010	COG2200	EAL domain
LZM82_14010	COG2771	luxR family
LZM82_14020	COG0673	inositol 2-dehydrogenase activity
LZM82_14025	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LZM82_14055	COG1342	Belongs to the UPF0251 family
LZM82_14065	COG1301	dicarboxylic acid transport
LZM82_14085	COG2814	Major facilitator Superfamily
LZM82_14090	COG0583	DNA-binding transcription factor activity
LZM82_14095	COG5001	Diguanylate cyclase
LZM82_14095	COG3300	MHYT domain
LZM82_14100	COG0739	heme binding
LZM82_14110	COG0659	secondary active sulfate transmembrane transporter activity
LZM82_14115	COG3314	Sporulation integral membrane protein YlbJ
LZM82_14135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LZM82_14140	COG0581	inorganic phosphate transmembrane transporter activity
LZM82_14145	COG0573	inorganic phosphate transmembrane transporter activity
LZM82_14150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LZM82_14180	COG1770	oligopeptidase
LZM82_14185	COG0513	Belongs to the DEAD box helicase family
LZM82_14195	COG1388	LysM domain
LZM82_14195	COG1376	ErfK ybiS ycfS ynhG family protein
LZM82_14200	COG0415	Belongs to the DNA photolyase family
LZM82_14210	COG3272	Protein of unknown function (DUF1722)
LZM82_14215	COG0813	purine-nucleoside phosphorylase activity
LZM82_14240	COG1566	PFAM secretion protein HlyD family protein
LZM82_14260	COG0786	glutamate:sodium symporter activity
LZM82_14275	COG1999	signal sequence binding
LZM82_14285	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LZM82_14290	COG0671	phosphoesterase, PA-phosphatase related
LZM82_14330	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LZM82_14335	COG0471	metal ion transport
LZM82_14365	COG4104	PAAR repeat-containing protein
LZM82_14370	COG3501	Rhs element vgr protein
LZM82_14380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LZM82_14385	COG1640	4-alpha-glucanotransferase
LZM82_14390	COG0058	SHG alpha-glucan phosphorylase activity
LZM82_14395	COG2909	trisaccharide binding
LZM82_14410	COG2084	Dehydrogenase
LZM82_14415	COG0217	transcriptional regulatory protein
LZM82_14450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LZM82_14455	COG1444	tRNA N-acetyltransferase activity
LZM82_14490	COG0642	Histidine kinase
LZM82_14495	COG2194	sulfuric ester hydrolase activity
LZM82_14505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LZM82_14510	COG0601	transmembrane transport
LZM82_14530	COG0643	Histidine kinase
LZM82_14530	COG2198	Histidine kinase
LZM82_14535	COG0643	Histidine kinase
LZM82_14535	COG2198	Histidine kinase
LZM82_14540	COG0835	chemotaxis
LZM82_14545	COG0835	chemotaxis
LZM82_14550	COG0840	transmembrane signaling receptor activity
LZM82_14555	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LZM82_14580	COG0745	RESPONSE REGULATOR receiver
LZM82_14620	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LZM82_14645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LZM82_14675	COG1982	Orn Lys Arg decarboxylase major
LZM82_14680	COG0531	amino acid
LZM82_14695	COG1901	pseudouridine methyltransferase
LZM82_14705	COG4221	oxidoreductase activity
LZM82_14710	COG0840	transmembrane signaling receptor activity
LZM82_14720	COG2910	NAD(P)H-binding
LZM82_14750	COG0673	inositol 2-dehydrogenase activity
LZM82_14755	COG3722	fumarate hydratase activity
LZM82_14760	COG0246	Mannitol dehydrogenase
LZM82_14765	COG2213	PTS system mannitol-specific
LZM82_14765	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZM82_14770	COG0739	heme binding
LZM82_14780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZM82_14785	COG4597	amino acid ABC transporter
LZM82_14790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LZM82_14800	COG1126	abc transporter atp-binding protein
LZM82_14805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LZM82_14815	COG0840	transmembrane signaling receptor activity
LZM82_14830	COG0840	transmembrane signaling receptor activity
LZM82_14845	COG4580	involved in the transport of maltose and maltodextrins
LZM82_14860	COG0363	glucosamine-6-phosphate deaminase activity
LZM82_14885	COG2259	Doxx family
LZM82_14890	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LZM82_14895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LZM82_14905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LZM82_14910	COG3366	ferrous iron transmembrane transporter activity
LZM82_14915	COG0700	Nucleoside recognition
LZM82_14925	COG0697	spore germination
LZM82_14930	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LZM82_14935	COG1764	response to oxidative stress
LZM82_14940	COG1846	Transcriptional regulator
LZM82_14960	COG2207	Transcriptional regulator
LZM82_14965	COG1280	lysine exporter protein (LysE YggA)
LZM82_14975	COG1902	pentaerythritol trinitrate reductase activity
LZM82_14985	COG1132	(ABC) transporter
LZM82_14995	COG1902	pentaerythritol trinitrate reductase activity
LZM82_15005	COG0583	DNA-binding transcription factor activity
LZM82_15010	COG0513	Belongs to the DEAD box helicase family
LZM82_15020	COG0840	transmembrane signaling receptor activity
LZM82_15030	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LZM82_15045	COG1620	l-lactate permease
LZM82_15055	COG0583	DNA-binding transcription factor activity
LZM82_15080	COG4172	Belongs to the ABC transporter superfamily
LZM82_15090	COG1067	ATP-dependent peptidase activity
LZM82_15095	COG0840	transmembrane signaling receptor activity
LZM82_15100	COG2211	Major facilitator Superfamily
LZM82_15110	COG3123	guanosine phosphorylase activity
LZM82_15115	COG1741	Belongs to the pirin family
LZM82_15125	COG5001	Diguanylate cyclase
LZM82_15130	COG0583	DNA-binding transcription factor activity
LZM82_15165	COG3706	GGDEF domain
LZM82_15170	COG1846	Transcriptional regulator
LZM82_15175	COG0784	Response regulator, receiver
LZM82_15175	COG0835	chemotaxis
LZM82_15180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LZM82_15190	COG0393	Putative heavy-metal-binding
LZM82_15205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LZM82_15210	COG3842	ATPase activity
LZM82_15220	COG1175	transmembrane transport
LZM82_15225	COG3833	ABC-type maltose transport systems, permease component
LZM82_15240	COG1349	DNA-binding transcription factor activity
LZM82_15245	COG2199	diguanylate cyclase activity
LZM82_15270	COG1278	Cold shock
LZM82_15275	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LZM82_15280	COG2354	Protein conserved in bacteria
LZM82_15285	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LZM82_15295	COG3152	Membrane
LZM82_15305	COG0418	dihydroorotase activity
LZM82_15310	COG3217	Mosc domain protein beta barrel domain protein
LZM82_15310	COG3217	Mosc domain protein beta barrel domain protein
LZM82_15310	COG0633	Ferredoxin
LZM82_15310	COG0633	Ferredoxin
LZM82_15345	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LZM82_15350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LZM82_15355	COG4558	Periplasmic binding protein
LZM82_15360	COG0848	biopolymer transport protein
LZM82_15365	COG0811	peptide transport
LZM82_15370	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LZM82_15380	COG3721	Heme iron utilization protein
LZM82_15385	COG0748	coenzyme F420 binding
LZM82_15395	COG3835	regulator
LZM82_15400	COG2610	gluconate transmembrane transporter activity
LZM82_15405	COG1929	Belongs to the glycerate kinase type-1 family
LZM82_15430	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LZM82_15435	COG0363	glucosamine-6-phosphate deaminase activity
LZM82_15440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LZM82_15445	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LZM82_15450	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LZM82_15470	COG0346	lactoylglutathione lyase activity
LZM82_15500	COG1063	alcohol dehydrogenase
LZM82_15555	COG0583	DNA-binding transcription factor activity
LZM82_15560	COG3048	D-serine ammonia-lyase activity
LZM82_15575	COG1294	oxidase, subunit
LZM82_15580	COG1271	oxidase subunit
LZM82_15585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LZM82_15590	COG1686	Belongs to the peptidase S11 family
LZM82_15600	COG3047	cAMP biosynthetic process
LZM82_15610	COG3227	Zinc metalloprotease (Elastase)
LZM82_15620	COG2267	carboxylic ester hydrolase activity
LZM82_15625	COG2067	long-chain fatty acid transport protein
LZM82_15635	COG0366	Alpha amylase catalytic
LZM82_15640	COG4989	oxidoreductase activity
LZM82_15650	COG1136	(ABC) transporter
LZM82_15655	COG0577	efflux transmembrane transporter activity
LZM82_15655	COG1136	(ABC) transporter
LZM82_15670	COG3275	phosphorelay sensor kinase activity
LZM82_15675	COG3279	Response regulator of the LytR AlgR family
LZM82_15690	COG0531	amino acid
LZM82_15715	COG1765	OsmC-like protein
LZM82_15720	COG1253	flavin adenine dinucleotide binding
LZM82_15745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LZM82_15760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LZM82_15765	COG3186	Phenylalanine-4-hydroxylase
LZM82_15775	COG0456	acetyltransferase
LZM82_15780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LZM82_15785	COG0662	Cupin 2, conserved barrel domain protein
LZM82_15790	COG0527	aspartate kinase activity
LZM82_15800	COG0459	protein refolding
LZM82_15805	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LZM82_15810	COG2239	Acts as a magnesium transporter
LZM82_15820	COG1166	arginine decarboxylase activity
LZM82_15825	COG0010	Belongs to the arginase family
LZM82_15835	COG3227	Zinc metalloprotease (Elastase)
LZM82_15840	COG3397	chitin binding
LZM82_15845	COG3046	protein related to deoxyribodipyrimidine photolyase
LZM82_15855	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LZM82_15870	COG0513	Belongs to the DEAD box helicase family
LZM82_15880	COG1368	sulfuric ester hydrolase activity
LZM82_15885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZM82_15900	COG0546	phosphoglycolate phosphatase activity
LZM82_15940	COG0484	heat shock protein binding
LZM82_15950	COG5001	Diguanylate cyclase
LZM82_15950	COG1716	ATPase activity
LZM82_15955	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LZM82_15965	COG4181	ATPase activity
LZM82_15970	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LZM82_15985	COG1984	allophanate hydrolase subunit 2
LZM82_15995	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LZM82_16000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LZM82_16005	COG0840	transmembrane signaling receptor activity
LZM82_16010	COG0814	amino acid
LZM82_16015	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LZM82_16020	COG0513	Belongs to the DEAD box helicase family
LZM82_16025	COG1309	transcriptional regulator
LZM82_16035	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LZM82_16040	COG0494	nUDIX hydrolase
LZM82_16050	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LZM82_16060	COG1126	abc transporter atp-binding protein
LZM82_16065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LZM82_16070	COG4215	(ABC) transporter
LZM82_16075	COG4160	amino acid transport
LZM82_16080	COG0583	DNA-binding transcription factor activity
LZM82_16110	COG3118	belongs to the thioredoxin family
LZM82_16115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZM82_16120	COG0247	lactate metabolic process
LZM82_16125	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
LZM82_16130	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LZM82_16135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LZM82_16140	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LZM82_16150	COG2926	Belongs to the UPF0265 family
LZM82_16170	COG1879	ABC-type sugar transport system periplasmic component
LZM82_16175	COG5002	protein histidine kinase activity
LZM82_16175	COG0784	Response regulator, receiver
LZM82_16215	COG1492	cobalamin metabolic process
LZM82_16220	COG0725	ABC transporter, periplasmic molybdate-binding protein
LZM82_16225	COG4149	molybdate abc transporter
LZM82_16230	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LZM82_16260	COG1289	transmembrane transporter activity
LZM82_16265	COG0210	DNA helicase
LZM82_16280	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LZM82_16285	COG1335	isochorismatase
LZM82_16290	COG1803	Methylglyoxal synthase
LZM82_16295	COG1879	ABC-type sugar transport system periplasmic component
LZM82_16300	COG0784	Response regulator, receiver
LZM82_16300	COG2198	Histidine kinase
LZM82_16300	COG2205	protein histidine kinase activity
LZM82_16305	COG0469	pyruvate kinase activity
LZM82_16310	COG2271	Major facilitator Superfamily
LZM82_16320	COG4191	Histidine kinase
LZM82_16335	COG1979	alcohol dehydrogenase
LZM82_16345	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LZM82_16365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZM82_16370	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZM82_16380	COG0183	Belongs to the thiolase family
LZM82_16390	COG3243	poly(R)-hydroxyalkanoic acid synthase
LZM82_16395	COG3842	ATPase activity
LZM82_16405	COG1840	ABC-type Fe3 transport system, periplasmic component
LZM82_16410	COG2271	Major facilitator Superfamily
LZM82_16415	COG3851	Histidine kinase
LZM82_16420	COG2197	response regulator
LZM82_16425	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LZM82_16445	COG0243	molybdopterin cofactor binding
LZM82_16455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LZM82_16460	COG3850	Histidine kinase
LZM82_16465	COG2197	response regulator
LZM82_16470	COG1609	Transcriptional regulator
LZM82_16490	COG1760	l-serine dehydratase
LZM82_16495	COG3069	C4-dicarboxylate transmembrane transporter activity
LZM82_16500	COG0840	transmembrane signaling receptor activity
LZM82_16505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LZM82_16510	COG0545	Peptidyl-prolyl cis-trans isomerase
LZM82_16515	COG2885	chlorophyll binding
LZM82_16525	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LZM82_16530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZM82_16535	COG1621	beta-fructofuranosidase activity
LZM82_16540	COG1609	Transcriptional regulator
LZM82_16545	COG1263	PTS System
LZM82_16545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LZM82_16590	COG0446	pyridine nucleotide-disulphide oxidoreductase
LZM82_16630	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LZM82_16635	COG0583	DNA-binding transcription factor activity
LZM82_16660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LZM82_16685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LZM82_16695	COG2390	Transcriptional regulator
LZM82_16700	COG2897	thiosulfate sulfurtransferase activity
LZM82_16710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LZM82_16720	COG0302	gtp cyclohydrolase
LZM82_16725	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LZM82_16725	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LZM82_16730	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LZM82_16735	COG1970	mechanosensitive ion channel activity
LZM82_16740	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LZM82_16750	COG1011	Hydrolase
LZM82_16755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LZM82_16760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LZM82_16765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LZM82_16770	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LZM82_16780	COG3842	ATPase activity
LZM82_16800	COG3104	oligopeptide transport
LZM82_16825	COG4166	transmembrane transport
LZM82_16830	COG4174	ABC transporter (Permease)
LZM82_16835	COG4239	(ABC) transporter, permease
LZM82_16840	COG4172	Belongs to the ABC transporter superfamily
LZM82_16845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LZM82_16860	COG0625	glutathione transferase activity
LZM82_16880	COG2050	protein possibly involved in aromatic compounds catabolism
LZM82_16895	COG1629	transport
LZM82_16895	COG4771	TonB-dependent receptor
LZM82_16900	COG0583	DNA-binding transcription factor activity
LZM82_16905	COG0045	succinate-CoA ligase (ADP-forming) activity
LZM82_16905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LZM82_16905	COG1042	CoA-binding domain protein
LZM82_16925	COG0023	Translation Initiation Factor
LZM82_16930	COG3140	Belongs to the UPF0181 family
LZM82_16945	COG0745	RESPONSE REGULATOR receiver
LZM82_16955	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LZM82_16960	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LZM82_16975	COG3706	GGDEF domain
LZM82_16995	COG2199	diguanylate cyclase activity
LZM82_17025	COG2824	Alkylphosphonate utilization operon protein PhnA
LZM82_17040	COG0737	Belongs to the 5'-nucleotidase family
LZM82_17045	COG3593	DNA synthesis involved in DNA repair
LZM82_17055	COG0583	DNA-binding transcription factor activity
LZM82_17060	COG2116	formate transmembrane transporter activity
LZM82_17070	COG3038	cytochrome b561
LZM82_17080	COG2200	EAL domain
LZM82_17090	COG0586	Pfam SNARE associated Golgi protein
LZM82_17095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LZM82_17100	COG0745	RESPONSE REGULATOR receiver
LZM82_17105	COG2205	protein histidine kinase activity
LZM82_17110	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZM82_17110	COG0674	pyruvate-flavodoxin oxidoreductase activity
LZM82_17110	COG1013	pyruvate-flavodoxin oxidoreductase activity
LZM82_17110	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LZM82_17125	COG0523	cobalamin synthesis protein
LZM82_17140	COG0156	8-amino-7-oxononanoate synthase activity
LZM82_17145	COG2205	protein histidine kinase activity
LZM82_17145	COG0784	Response regulator, receiver
LZM82_17150	COG0419	ATPase involved in DNA repair
LZM82_17155	COG0420	3'-5' exonuclease activity
LZM82_17160	COG1609	Transcriptional regulator
LZM82_17165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZM82_17165	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZM82_17170	COG1105	Belongs to the carbohydrate kinase PfkB family
LZM82_17175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LZM82_17175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LZM82_17175	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LZM82_17180	COG0189	ligase activity
LZM82_17180	COG4067	protein conserved in archaea
LZM82_17190	COG0602	queuosine metabolic process
LZM82_17195	COG1328	CTP reductase activity
LZM82_17210	COG0346	lactoylglutathione lyase activity
LZM82_17380	COG0346	lactoylglutathione lyase activity
LZM82_17410	COG3039	Transposase
LZM82_17425	COG2944	sequence-specific DNA binding
LZM82_17430	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
LZM82_17510	COG4977	sequence-specific DNA binding
LZM82_17570	COG3040	lipid binding
LZM82_17595	COG1619	proteins homologs of microcin C7 resistance protein MccF
LZM82_17620	COG3093	addiction module antidote protein HigA
LZM82_17625	COG3549	Plasmid maintenance system killer
LZM82_17655	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LZM82_17840	COG1280	lysine exporter protein (LysE YggA)
LZM82_17850	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LZM82_17870	COG3040	lipid binding
LZM82_17885	COG0346	lactoylglutathione lyase activity
LZM82_17935	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LZM82_17945	COG1619	proteins homologs of microcin C7 resistance protein MccF
LZM82_18050	COG3041	Addiction module toxin RelE StbE family
LZM82_18055	COG3328	transposase activity
LZM82_18085	COG3040	lipid binding
LZM82_18090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LZM82_18105	COG0494	nUDIX hydrolase
LZM82_18130	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LZM82_18170	COG1028	Short-chain dehydrogenase reductase Sdr
LZM82_18225	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LZM82_18230	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LZM82_18265	COG3039	Transposase
LZM82_18275	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LZM82_18285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LZM82_18290	COG0509	glycine decarboxylation via glycine cleavage system
LZM82_18295	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LZM82_18295	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LZM82_18320	COG1686	Belongs to the peptidase S11 family
LZM82_18335	COG2814	Major facilitator Superfamily
LZM82_18350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LZM82_18375	COG5002	protein histidine kinase activity
LZM82_18380	COG0745	RESPONSE REGULATOR receiver
LZM82_18405	COG0366	Alpha amylase catalytic
LZM82_18410	COG3038	cytochrome b561
LZM82_18440	COG0561	phosphatase activity
LZM82_18445	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LZM82_18450	COG3623	hexulose-6-phosphate isomerase
LZM82_18460	COG0745	RESPONSE REGULATOR receiver
LZM82_18480	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LZM82_18495	COG2207	Transcriptional regulator
LZM82_18500	COG4604	ABC transporter, ATP-binding protein
LZM82_18505	COG4605	iron ion homeostasis
LZM82_18510	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LZM82_18535	COG5380	lipid catabolic process
LZM82_18540	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LZM82_18545	COG0840	transmembrane signaling receptor activity
LZM82_18555	COG3240	lipase activity
LZM82_18560	COG3706	GGDEF domain
LZM82_18570	COG2814	Major facilitator Superfamily
LZM82_18575	COG1757	Na H antiporter
LZM82_18585	COG4191	Histidine kinase
LZM82_18585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LZM82_18590	COG3437	response regulator, receiver
LZM82_18590	COG0784	Response regulator, receiver
LZM82_18595	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LZM82_18600	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LZM82_18605	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LZM82_18610	COG0513	Belongs to the DEAD box helicase family
LZM82_18645	COG0516	GMP reductase activity
LZM82_18655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LZM82_18665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LZM82_18670	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LZM82_18670	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LZM82_18695	COG3036	rescue of stalled ribosome
LZM82_18700	COG1278	Cold shock
LZM82_18705	COG1017	nitric oxide dioxygenase activity
LZM82_18705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LZM82_18710	COG3604	Transcriptional regulator
