locus-tag	class	description
F0316_00040	ENOG4105WMR	Protein CrcB homolog
F0316_00045	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
F0316_00055	ENOG4105D06	uba thif-type nad fad binding protein
F0316_00060	ENOG4105WHD	thiamine biosynthesis protein ThiS
F0316_00065	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
F0316_00070	ENOG4105D41	biosynthesis protein thiH
F0316_00075	ENOG4105DC7	peptidase M24
F0316_00075	ENOG4105DC7	peptidase M24
F0316_00085	ENOG4105CNH	Multidrug resistance protein MdtL
F0316_00095	ENOG4108VVK	transcriptional Regulator, AsnC
F0316_00100	ENOG4105BZU	Histidine kinase
F0316_00105	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
F0316_00115	ENOG4105EMK	carboxylate amino acid amine transporter
F0316_00120	ENOG4108M6U	Universal stress protein A
F0316_00130	ENOG41090A1	ferritin
F0316_00135	ENOG4108V6B	universal stress protein B
F0316_00140	ENOG4105CBX	hi0933 family
F0316_00150	ENOG4105CGY	Dna recombination protein
F0316_00155	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
F0316_00160	ENOG4105JC1	sterol-binding domain protein
F0316_00165	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
F0316_00170	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
F0316_00175	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
F0316_00180	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
F0316_00185	ENOG4107R73	Mate efflux family protein
F0316_00195	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
F0316_00205	ENOG4105E55	glycerol-3-phosphate acyltransferase
F0316_00210	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
F0316_00215	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
F0316_00225	ENOG4105X6C	Flagellar basal body-associated protein FliL
F0316_00230	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_00240	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
F0316_00250	ENOG4105F8V	Hydrolase, tatD family
F0316_00255	ENOG4105D52	delta-aminolevulinic acid dehydratase
F0316_00265	ENOG4105C2M	dna polymerase I
F0316_00270	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
F0316_00275	ENOG4106RE7	Cytochrome
F0316_00285	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
F0316_00290	ENOG4105XCT	Protein of unknown function (DUF2489)
F0316_00295	ENOG4105D4P	Coproporphyrinogen iii oxidase
F0316_00300	ENOG410601J	HemY protein
F0316_00305	ENOG4105ECF	c-methyltransferase
F0316_00310	ENOG41076E6	Uroporphyrinogen-III Synthase
F0316_00315	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
F0316_00325	ENOG4107T0K	Adenylate cyclase
F0316_00330	ENOG4105XQ6	frataxin-like protein
F0316_00340	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
F0316_00345	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
F0316_00350	ENOG4105CT0	Protein of unknown function, DUF484
F0316_00355	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
F0316_00360	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
F0316_00365	ENOG4105BZU	Histidine kinase
F0316_00385	ENOG4105DQF	Hydrolase
F0316_00390	ENOG4108EUD	Lysophospholipase
F0316_00395	ENOG410829K	Lysine exporter protein (Lyse ygga)
F0316_00400	ENOG4105D58	Diguanylate phosphodiesterase
F0316_00405	ENOG4108RMU	ferritin dps family protein
F0316_00445	ENOG4106H78	methyltransferase
F0316_00450	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
F0316_00455	ENOG4105CAK	Cell division ATP-binding protein ftsE
F0316_00460	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
F0316_00465	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F0316_00470	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
F0316_00485	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
F0316_00495	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F0316_00500	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
F0316_00505	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
F0316_00575	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
F0316_00580	ENOG4105BZU	Histidine kinase
F0316_00585	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F0316_00590	ENOG4105CUX	Signal transduction histidine kinase
F0316_00600	ENOG4105C5F	glutamine synthetase
F0316_00615	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
F0316_00625	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
F0316_00630	ENOG4105SUU	thioesterase domain
F0316_00640	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
F0316_00645	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
F0316_00650	ENOG4105VEJ	Heat shock protein
F0316_00655	ENOG4108XKW	General secretion pathway protein C
F0316_00665	ENOG4107QHF	type ii secretion system protein e
F0316_00670	ENOG4105D7Q	type ii secretion system
F0316_00675	ENOG4108VAU	general secretion pathway protein G
F0316_00680	ENOG4105VWV	general secretion pathway protein h
F0316_00685	ENOG4105X5Z	General secretion pathway protein I
F0316_00690	ENOG4108WWZ	General secretion pathway protein J
F0316_00695	ENOG4108RTD	type II secretion system protein K
F0316_00700	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
F0316_00705	ENOG4105U1E	general secretion pathway protein M
F0316_00710	ENOG4105PIC	general secretion pathway protein N
F0316_00715	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
F0316_00720	ENOG4107RK2	ADP-ribose diphosphatase NudE
F0316_00725	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
F0316_00730	ENOG4105MJ2	Competence protein
F0316_00735	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
F0316_00745	ENOG4105BZM	domain protein
F0316_00750	ENOG4108RRZ	Transcription elongation factor GreB
F0316_00755	ENOG4108KHX	Diguanylate cyclase
F0316_00760	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
F0316_00765	ENOG4105E0F	Histidine kinase
F0316_00770	ENOG4105C2W	permease
F0316_00775	ENOG4105CB5	ATP-dependent DNA helicase recG
F0316_00780	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
F0316_00785	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
F0316_00790	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
F0316_00795	ENOG4105EX9	Membrane
F0316_00800	ENOG4107QN1	sodium solute
F0316_00810	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
F0316_00820	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
F0316_00830	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
F0316_00835	ENOG4108IJ0	Aspartate ammonia-lyase
F0316_00840	ENOG4105BZU	Histidine kinase
F0316_00845	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
F0316_00850	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
F0316_00860	ENOG4105E0F	Histidine kinase
F0316_00865	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
F0316_00875	ENOG41076HS	cation diffusion facilitator family transporter
F0316_00880	ENOG4105CTQ	phosphohexokinase
F0316_00885	ENOG4105CBT	Fructose-1,6-bisphosphatase
F0316_00890	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
F0316_00895	ENOG4105SYT	Methylenetetrahydrofolate reductase
F0316_00900	ENOG4105CFH	Aspartokinase
F0316_00905	ENOG4105C28	cystathionine
F0316_00910	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
F0316_00915	ENOG4105C6K	Malic enzyme
F0316_00920	ENOG4105VFB	Binds the 23S rRNA (By similarity)
F0316_00925	ENOG4105C25	Primosomal protein n'
F0316_00930	ENOG4105ETE	Transcriptional regulator (LacI family
F0316_00935	ENOG41063M6	Cell Division Protein
F0316_00940	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
F0316_00945	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
F0316_00950	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
F0316_00955	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
F0316_00965	ENOG4105CP7	Triose-phosphate isomerase
F0316_00995	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
F0316_01000	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
F0316_01010	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
F0316_01015	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
F0316_01020	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
F0316_01025	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
F0316_01030	ENOG4105E33	succinate dehydrogenase
F0316_01040	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
F0316_01045	ENOG4107YZP	Rhodanese domain protein
F0316_01050	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
F0316_01055	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
F0316_01060	ENOG4105D7W	serine acetyltransferase
F0316_01070	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
F0316_01075	ENOG4105CWC	Acetylornithine deacetylase
F0316_01080	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
F0316_01085	ENOG4105CAS	nag kinase
F0316_01090	ENOG4105CDH	Citrulline--aspartate ligase
F0316_01095	ENOG4105CH7	arginosuccinase
F0316_01105	ENOG4107QN2	dihydrolipoyl dehydrogenase
F0316_01110	ENOG4105EHV	domain protein
F0316_01120	ENOG4108JQC	penicillin-binding protein 1A
F0316_01145	ENOG4105E4G	Type IV pilus
F0316_01150	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
F0316_01155	ENOG4105D49	3-dehydroquinate synthase
F0316_01165	ENOG4105DFE	Dna adenine methylase
F0316_01170	ENOG4105DJV	ribulose-phosphate 3-epimerase
F0316_01175	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
F0316_01180	ENOG4105C31	Tryptophanyl-tRNA synthetase
F0316_01195	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
F0316_01200	ENOG4105DDQ	anthranilate synthase
F0316_01205	ENOG4105C8Y	Acetylornithine aminotransferase
F0316_01225	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
F0316_01230	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
F0316_01240	ENOG4105DNZ	Alpha Beta Hydrolase
F0316_01250	ENOG4105C5H	ABC transporter
F0316_01255	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
F0316_01270	ENOG4108YZY	peptidylprolyl cis-trans isomerase
F0316_01275	ENOG4105D44	asparaginase
F0316_01280	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
F0316_01290	ENOG4108UV7	flagellar protein motX
F0316_01295	ENOG4105E68	Sulfatase
F0316_01300	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
F0316_01305	ENOG4105C2N	RNA methyltransferase TrmH family group 3
F0316_01310	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
F0316_01315	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
F0316_01320	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
F0316_01325	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
F0316_01330	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F0316_01335	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
F0316_01340	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
F0316_01345	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
F0316_01350	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
F0316_01355	ENOG41083MP	50s ribosomal protein l29
F0316_01360	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
F0316_01365	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
F0316_01370	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
F0316_01375	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F0316_01380	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
F0316_01385	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
F0316_01390	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
F0316_01395	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
F0316_01400	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
F0316_01405	ENOG4105VPB	50S ribosomal protein L30
F0316_01410	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
F0316_01415	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
F0316_01425	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F0316_01430	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
F0316_01435	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
F0316_01440	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F0316_01445	ENOG4108ZT0	50S ribosomal protein l17
F0316_01455	ENOG4108V1T	peptidylprolyl cis-trans isomerase
F0316_01460	ENOG4108UBT	opacity-associated protein
F0316_01465	ENOG4108SXK	Transporter Drug Metabolite Exporter family
F0316_01470	ENOG4107YB6	acetyltransferase, (GNAT) family
F0316_01475	ENOG4105C1J	atp-dependent rna helicase
F0316_01485	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
F0316_01490	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
F0316_01495	ENOG4105C11	sulfate adenylyltransferase), subunit 2
F0316_01500	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
F0316_01505	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
F0316_01525	ENOG4105C19	ABC transporter
F0316_01540	ENOG4108UUE	Transcriptional regulator
F0316_01545	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
F0316_01550	ENOG4105CFU	surface antigen
F0316_01560	ENOG41066HZ	AIG2-like family
F0316_01565	ENOG4105F0N	pyrophosphate phospho-hydrolase
F0316_01570	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
F0316_01580	ENOG4105DFU	Cell wall formation (By similarity)
F0316_01585	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
F0316_01590	ENOG4105DP9	ABC transporter
F0316_01595	ENOG4106SMU	thiamine transporter membrane protein
F0316_01600	ENOG4107T0D	ABC, transporter
F0316_01605	ENOG4105N42	UPF0307 protein
F0316_01610	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
F0316_01615	ENOG4105CJW	magnesium transporter
F0316_01620	ENOG41080Z8	PHOSPHOCARRIER protein
F0316_01630	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
F0316_01635	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
F0316_01640	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F0316_01645	ENOG4108IUZ	ABC transporter
F0316_01650	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
F0316_01660	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
F0316_01665	ENOG4105C2X	Arabinose 5-phosphate isomerase
F0316_01680	ENOG4105DHJ	ABC, transporter
F0316_01685	ENOG4105CY3	ABC transporter, permease
F0316_01690	ENOG4107PE3	Mammalian cell entry related domain protein
F0316_01695	ENOG4105E3I	toluene tolerance
F0316_01705	ENOG4105VFK	BolA family
F0316_01710	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
F0316_01715	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
F0316_01720	ENOG4105KME	endoribonuclease L-psp
F0316_01725	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
F0316_01730	ENOG4105CXT	aspartate transcarbamylase
F0316_01735	ENOG4105DBV	ornithine carbamoyltransferase
F0316_01740	ENOG4108IAB	Phoh family
F0316_01750	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
F0316_01755	ENOG4105D3G	Pseudouridine synthase
F0316_01760	ENOG4105C5I	Dehydrogenase
F0316_01765	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
F0316_01770	ENOG4105MYG	DNA polymerase iii, chi subunit
F0316_01775	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
F0316_01780	ENOG4108M8S	permease YjgP YjgQ family protein
F0316_01785	ENOG4108K5H	permease YjgP YjgQ family protein
F0316_01800	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
F0316_01845	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
F0316_01850	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
F0316_01855	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
F0316_01860	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
F0316_01880	ENOG41064T2	transcriptional regulator, lysR family
F0316_01885	ENOG4108IQE	Amp-dependent synthetase and ligase
F0316_01890	ENOG4105C7K	acetolactate synthase
F0316_01895	ENOG4108ZP8	Acetolactate synthase small subunit
F0316_01900	ENOG4108JQ1	Dehydrogenase
F0316_01905	ENOG4105E66	phosphoriboisomerase A
F0316_01910	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
F0316_01920	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
F0316_01930	ENOG4105D0A	hydroxylase
F0316_01935	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
F0316_01945	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
F0316_01950	ENOG4105Y75	tpr repeat protein
F0316_01960	ENOG4108IYU	L-aspartate oxidase
F0316_01970	ENOG4105EMN	RNA polymerase sigma factor
F0316_01980	ENOG4105VQK	sigma E regulatory protein, MucB RseB
F0316_01985	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
F0316_01990	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
F0316_01995	ENOG4105C3F	Signal peptidase i
F0316_02000	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
F0316_02005	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
F0316_02010	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
F0316_02015	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
F0316_02020	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
F0316_02040	ENOG4105BZU	Histidine kinase
F0316_02045	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
F0316_02050	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
F0316_02055	ENOG4105DXN	mazG family
F0316_02060	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
F0316_02065	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
F0316_02070	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
F0316_02085	ENOG4106MWK	domain protein
F0316_02090	ENOG4105CJ3	phosphate transporter
F0316_02095	ENOG4107IX6	phosphate transport regulator
F0316_02100	ENOG4105I7R	Adenylate cyclase
F0316_02105	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_02110	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
F0316_02115	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
F0316_02120	ENOG4105DFG	type I secretion outer membrane protein
F0316_02125	ENOG41087AY	ADP-Ribose pyrophosphatase
F0316_02130	ENOG4108SX3	cytoplasmic protein
F0316_02135	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
F0316_02140	ENOG4105IPS	esterase
F0316_02145	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F0316_02150	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F0316_02155	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
F0316_02160	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
F0316_02165	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
F0316_02170	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
F0316_02175	ENOG4105D7Q	type ii secretion system
F0316_02180	ENOG4107QHF	type ii secretion system protein e
F0316_02185	ENOG4105X0D	Fimbrial protein
F0316_02190	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
F0316_02200	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
F0316_02205	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
F0316_02210	ENOG4105T95	Thiol disulfide interChange protein
F0316_02215	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
F0316_02220	ENOG4105CGH	5'-nucleotidase
F0316_02230	ENOG41073TP	transcriptional regulator
F0316_02235	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
F0316_02240	ENOG4107QSN	dihydrolipoamide acetyltransferase
F0316_02245	ENOG4107QN2	dihydrolipoyl dehydrogenase
F0316_02255	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
F0316_02260	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
F0316_02265	ENOG4105CJN	penicillin-binding protein
F0316_02270	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
F0316_02275	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
F0316_02280	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
F0316_02285	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
F0316_02295	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
F0316_02300	ENOG4105DFU	Cell wall formation (By similarity)
F0316_02305	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
F0316_02310	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
F0316_02315	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
F0316_02320	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F0316_02330	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
F0316_02335	ENOG4105M6F	mutator MutT protein
F0316_02340	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
F0316_02350	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
F0316_02355	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
F0316_02370	ENOG4105EJ9	Membrane
F0316_02375	ENOG4105VP0	transcriptional regulator, lysR family
F0316_02380	ENOG4105EN6	Membrane
F0316_02385	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
F0316_02395	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
F0316_02405	ENOG4105BZ8	glutamate synthase
F0316_02410	ENOG4105CBC	glutamate synthase
F0316_02425	ENOG4105N5T	Radical SAM Protein
F0316_02435	ENOG4105BZU	Histidine kinase
F0316_02440	ENOG41065U4	response regulator
F0316_02450	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
F0316_02470	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
F0316_02475	ENOG4105D98	threonine synthase
F0316_02480	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
F0316_02485	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
F0316_02490	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
F0316_02505	ENOG4105BZG	amino acid carrier protein
F0316_02515	ENOG4105EYA	deoxyribonuclease
F0316_02520	ENOG4105D9N	nucleoside
F0316_02530	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
F0316_02535	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
F0316_02540	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
F0316_02545	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
F0316_02555	ENOG4105EAC	phosphoserine phosphatase
F0316_02565	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
F0316_02570	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
F0316_02575	ENOG4108IQE	Amp-dependent synthetase and ligase
F0316_02580	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
F0316_02590	ENOG4105CNT	hydrolase family 2
F0316_02595	ENOG41060NJ	transcriptional regulator
F0316_02600	ENOG4108Y51	tRNA-binding protein
F0316_02615	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
F0316_02620	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
F0316_02630	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
F0316_02635	ENOG4105X2V	dna damage-inducible protein
F0316_02650	ENOG4105DSY	exodeoxyribonuclease V, gamma
F0316_02655	ENOG4107QKA	exodeoxyribonuclease V beta
F0316_02660	ENOG4107QYX	exodeoxyribonuclease v alpha
F0316_02670	ENOG4107QZM	n-acetylglutamate synthase
F0316_02680	ENOG4105CA3	membrane-bound lytic murein transglycosylase
F0316_02685	ENOG4105CUZ	uba thif-type nad fad binding protein
F0316_02690	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
F0316_02695	ENOG4105C9B	Cysteine desulfurase
F0316_02700	ENOG4107S0N	DJ-1 family
F0316_02705	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
F0316_02710	ENOG4105DRB	nucleoside-specific channel-forming protein
F0316_02720	ENOG4105K6V	RNA polymerase
F0316_02730	ENOG4105EYM	Major Facilitator superfamily
F0316_02735	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
F0316_02745	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
F0316_02750	ENOG4105M85	Bola protein
F0316_02755	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
F0316_02760	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
F0316_02765	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
F0316_02770	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
F0316_02775	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
F0316_02780	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
F0316_02785	ENOG4105CJ2	(LipO)protein
F0316_02795	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
F0316_02805	ENOG4105BZU	Histidine kinase
F0316_02810	ENOG4105C8J	)-transporter
F0316_02820	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
F0316_02830	ENOG4105CIN	aminoacyl-histidine dipeptidase
F0316_02835	ENOG4105C7N	Xanthine uracil vitamin C permease
F0316_02840	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
F0316_02850	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
F0316_02855	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
F0316_02860	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
F0316_02865	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
F0316_02870	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
F0316_02885	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
F0316_02890	ENOG4107YIM	Involved in the transcription termination process (By similarity)
F0316_02895	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
F0316_02900	ENOG4108ZAI	phosphatidylglycerophosphatase a
F0316_02905	ENOG4108T8E	UPF0325 protein
F0316_02910	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
F0316_02915	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
F0316_02920	ENOG4105CE9	30S ribosomal protein S2
F0316_02925	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
F0316_02930	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
F0316_02935	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
F0316_02940	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
F0316_02945	ENOG4105KNE	Phosphatidate cytidylyltransferase
F0316_02950	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
F0316_02955	ENOG4105DZP	Membrane-associated zinc metalloprotease
F0316_02965	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
F0316_02970	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F0316_02975	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
F0316_02980	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F0316_02985	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F0316_02990	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
F0316_02995	ENOG4105C0B	DNA polymerase III (alpha subunit)
F0316_03000	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
F0316_03005	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
F0316_03010	ENOG4105N7H	Cytochrome
F0316_03015	ENOG4105PY6	Phenolic acid decarboxylase
F0316_03020	ENOG4108YZA	Nitrogen regulatory protein pii
F0316_03030	ENOG4105E9H	Lytic Murein transglycosylase
F0316_03035	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
F0316_03040	ENOG4105D1A	Methyltransferase
F0316_03045	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
F0316_03050	ENOG4108JDX	DNA polymerase iii, epsilon subunit
F0316_03060	ENOG4107QPN	acyl-Coa dehydrogenase
F0316_03065	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
F0316_03070	ENOG4105E7A	Glutamine amidotransferase
F0316_03075	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
F0316_03080	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
F0316_03085	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
F0316_03090	ENOG4105BZU	Histidine kinase
F0316_03095	ENOG4105FE9	pseudouridine synthase
F0316_03100	ENOG4108DG9	Smr protein MutS2
F0316_03115	ENOG4105MBR	gumn family
F0316_03120	ENOG4105E2D	ec 3.2.1.52
F0316_03130	ENOG4105C59	p-type ATPase
F0316_03135	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
F0316_03140	ENOG4105UYK	outer membrane protein a
F0316_03150	ENOG4107RBR	Receptor
F0316_03155	ENOG4105Q26	Siderophore-interacting protein
F0316_03195	ENOG4107R88	Chemotaxis protein (CheV)
F0316_03200	ENOG4105BZU	Histidine kinase
F0316_03205	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
F0316_03210	ENOG4108ZC9	flagellar basal-body rod protein flgc
F0316_03215	ENOG4105W00	Flagellar hook capping protein
F0316_03220	ENOG4105BZE	flagellar hook protein, FlgE
F0316_03225	ENOG4108KPB	Flagellar basal-body rod protein FlgF
F0316_03230	ENOG4105CGA	flagellar basal-body rod protein FlgG
F0316_03235	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
F0316_03240	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
F0316_03245	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
F0316_03260	ENOG4105I03	Flagellin
F0316_03265	ENOG4105I03	Flagellin
F0316_03350	ENOG4105C3G	gtp-binding protein
F0316_03355	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
F0316_03360	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
F0316_03365	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
F0316_03370	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
F0316_03375	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
F0316_03380	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
F0316_03385	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
F0316_03390	ENOG4108YY7	Invasion gene expression up-regulator SirB
F0316_03395	ENOG41063JG	Transcriptional regulator
F0316_03400	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
F0316_03405	ENOG4105CGH	5'-nucleotidase
F0316_03410	ENOG4108Z66	YbaK ebsC protein
F0316_03415	ENOG4105C2W	permease
F0316_03430	ENOG4105CS1	NAD(P)H quinone oxidoreductase
F0316_03435	ENOG4105K89	arsenate reductase
F0316_03440	ENOG4105ERG	peptidase m48, ste24p
F0316_03455	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_03460	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F0316_03470	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
F0316_03475	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
F0316_03485	ENOG4108RS6	transposase
F0316_03500	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
F0316_03505	ENOG4105KUZ	arsenate reductase
F0316_03520	ENOG4105QZU	Inner membrane protein YfeZ
F0316_03525	ENOG4105EZR	dyp-type peroxidase family protein
F0316_03530	ENOG4105I03	Flagellin
F0316_03535	ENOG4105I03	Flagellin
F0316_03540	ENOG4105I03	Flagellin
F0316_03545	ENOG41063QE	flagellar protein FlaG
F0316_03550	ENOG4107W9T	flagellar hook-associated
F0316_03560	ENOG4105MQ3	flagellar protein FliS
F0316_03565	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F0316_03570	ENOG4105BZU	Histidine kinase
F0316_03575	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F0316_03580	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
F0316_03585	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
F0316_03590	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
F0316_03595	ENOG4105W2B	Flagellar assembly protein
F0316_03600	ENOG4108JIR	Flagellum-specific ATP synthase
F0316_03620	ENOG4105X6C	Flagellar basal body-associated protein FliL
F0316_03625	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
F0316_03630	ENOG4105DD5	Flagellar motor switch protein
F0316_03635	ENOG4105VTB	flagellar biosynthesis protein fliO
F0316_03640	ENOG4105CN7	Flagellar biosynthetic protein FliP
F0316_03645	ENOG4105VS8	Flagellar biosynthetic protein fliq
F0316_03650	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
F0316_03655	ENOG4105D00	flagellar biosynthetic protein flhB
F0316_03665	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
F0316_03675	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
F0316_03680	ENOG4105EN6	Membrane
F0316_03685	ENOG4108BPE	-transporting atpase
F0316_03690	ENOG4105MH2	YfcL protein
F0316_03695	ENOG4105Q8W	reductase
F0316_03700	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
F0316_03705	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
F0316_03710	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
F0316_03715	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
F0316_03720	ENOG41090R7	Ferric uptake
F0316_03730	ENOG4105CMU	LysR family (Transcriptional regulator
F0316_03735	ENOG4105VAW	lrga family
F0316_03740	ENOG41067MG	lrgb family
F0316_03745	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
F0316_03755	ENOG4105EV9	Alpha Beta Hydrolase
F0316_03760	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
F0316_03765	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
F0316_03775	ENOG4107QNR	UPF0135 protein
F0316_03780	ENOG4105BZN	citrate synthase
F0316_03785	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
F0316_03790	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
F0316_03795	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
F0316_03800	ENOG4105E33	succinate dehydrogenase
F0316_03805	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
F0316_03810	ENOG4105C7S	Dehydrogenase
F0316_03815	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
F0316_03820	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
F0316_03825	ENOG4105FAV	ABC, transporter
F0316_03830	ENOG4105FDK	ABC transporter
F0316_03835	ENOG4105NXV	High-affinity zinc uptake system protein
F0316_03840	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
F0316_03845	ENOG4105XFK	Ferrous iron transport protein A
F0316_03865	ENOG4105C75	arginyL-tRNA synthetase
F0316_03875	ENOG4108JQM	Insulinase (Peptidase family M16)
F0316_03880	ENOG4108BY2	phosphohistidine phosphatase
F0316_03885	ENOG4105D7B	Flagellar biosynthesis protein flha
F0316_03890	ENOG4105FZW	flagellar biosynthesis regulator FlhF
F0316_03895	ENOG4107R21	site-determining protein
F0316_03900	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F0316_03905	ENOG4108VYJ	response regulator receiver protein
F0316_03910	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
F0316_03915	ENOG4105CBS	Chea signal transduction histidine kinase
F0316_03920	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
F0316_03925	ENOG4107QJE	Chromosome Partitioning Protein
F0316_03935	ENOG4108V3W	Chemotaxis protein, CheW
F0316_03945	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
F0316_03950	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
F0316_03955	ENOG41060IM	Heme exporter protein
F0316_03960	ENOG41067VX	Heme exporter protein
F0316_03965	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
F0316_03970	ENOG4105DA4	cytochrome c-type biogenesis protein
F0316_03975	ENOG4107QX9	Thiol disulfide interChange protein
F0316_03980	ENOG4108M1T	Cytochrome c-type biogenesis protein
F0316_03990	ENOG410903C	(LipO)protein
F0316_04005	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
F0316_04010	ENOG4105M2J	Glutaredoxin
F0316_04015	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
F0316_04020	ENOG4105DGU	Histone deacetylase
F0316_04035	ENOG4105E68	Sulfatase
F0316_04045	ENOG4106V8H	Nucleoid-associated protein
F0316_04055	ENOG4105DFD	Na H antiporter
F0316_04060	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
F0316_04065	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
F0316_04070	ENOG4108EKI	Dehydrogenase
F0316_04085	ENOG4105CHH	sulfate transporter
F0316_04090	ENOG4105C03	ribonuclease
F0316_04105	ENOG4105EI2	Pseudouridine synthase
F0316_04110	ENOG4108UHJ	MAF-like protein
F0316_04115	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
F0316_04120	ENOG4105VGS	50s ribosomal protein l32
F0316_04125	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
F0316_04130	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
F0316_04135	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
F0316_04140	ENOG4105CHR	reductase
F0316_04145	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
F0316_04150	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
F0316_04155	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
F0316_04160	ENOG4105HHA	aminodeoxychorismate lyase
F0316_04165	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
F0316_04170	ENOG4107QRG	dna polymerase iii
F0316_04175	ENOG4105F8V	Hydrolase, tatD family
F0316_04180	ENOG4105CI1	PTS System
F0316_04190	ENOG4105C8J	)-transporter
F0316_04205	ENOG4108NRW	Phospholipase, patatin family
F0316_04210	ENOG4105CA9	Pyruvate kinase
F0316_04215	ENOG4105DAG	ROK family
F0316_04220	ENOG4107R88	Chemotaxis protein (CheV)
F0316_04235	ENOG4105DHI	Methyltransferase
F0316_04245	ENOG4105DSB	aldose 1-epimerase
F0316_04250	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
F0316_04255	ENOG4105E0X	reductase
F0316_04270	ENOG4105VUT	cytoplasmic protein
F0316_04275	ENOG4105HDK	L-asparaginase
F0316_04280	ENOG4105D07	Signal peptide peptidase, SppA
F0316_04285	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
F0316_04290	ENOG4105CIY	formyltetrahydrofolate deformylase
F0316_04305	ENOG4105DVT	helicase
F0316_04310	ENOG41072GX	Peptidase M22 Glycoprotease
F0316_04325	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
F0316_04330	ENOG4105CEY	Amp-dependent synthetase and ligase
F0316_04335	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
F0316_04350	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
F0316_04355	ENOG4105DK2	UPF0207 protein
F0316_04360	ENOG4105CHM	Aminotransferase
F0316_04365	ENOG4105E4F	Isochorismate synthase
F0316_04370	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
F0316_04375	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
F0316_04380	ENOG4108IPT	Naphthoate synthase
F0316_04385	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
F0316_04390	ENOG4105CEY	Amp-dependent synthetase and ligase
F0316_04395	ENOG4105DKK	Benzoate
F0316_04400	ENOG4108JCI	Transcriptional regulator
F0316_04405	ENOG4108N3W	hemolysin secretion protein
F0316_04410	ENOG4107S74	Lysophospholipid transporter LplT
F0316_04435	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
F0316_04440	ENOG4107QMS	site-determining protein
F0316_04445	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
F0316_04450	ENOG4105VNG	YcgL domain-containing protein
F0316_04455	ENOG4105CVE	Lytic murein transglycosylase
F0316_04460	ENOG4105JQN	Transcriptional regulator
F0316_04465	ENOG4105D9N	nucleoside
F0316_04470	ENOG410662T	chitinase
F0316_04475	ENOG4105CUW	cytochrome C-TYPE protein
F0316_04480	ENOG4107QY8	reductase
F0316_04495	ENOG4105JQN	Transcriptional regulator
F0316_04510	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
F0316_04550	ENOG4108HPI	phosphatidate Cytidylyltransferase
F0316_04560	ENOG4105BZU	Histidine kinase
F0316_04575	ENOG4105CNG	UPF0061 protein
F0316_04580	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
F0316_04585	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
F0316_04590	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
F0316_04595	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F0316_04610	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
F0316_04615	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
F0316_04620	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
F0316_04625	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
F0316_04630	ENOG4105K70	DNA-binding protein
F0316_04635	ENOG4105EIN	peptidylprolyl cis-trans isomerase
F0316_04640	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
F0316_04645	ENOG4105CAT	Cytidine monophosphate kinase
F0316_04650	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
F0316_04655	ENOG4108RS6	transposase
F0316_04660	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
F0316_04665	ENOG4105Q4A	inner membrane protein yciS
F0316_04670	ENOG4105CFV	Tetratricopeptide repeat protein
F0316_04675	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
F0316_04685	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
F0316_04700	ENOG4108JQ7	(ABC) transporter
F0316_04715	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
F0316_04725	ENOG4107R11	Transcriptional regulator
F0316_04735	ENOG4105DCF	alanine dehydrogenase
F0316_04740	ENOG4105EW9	transcriptional regulator AsnC family
F0316_04745	ENOG4105CNU	cell division protein FtsK
F0316_04750	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
F0316_04755	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
F0316_04760	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
F0316_04770	ENOG4108NVR	Methyl-accepting chemotaxis
F0316_04775	ENOG4105K59	histidine triad (HIT) protein
F0316_04805	ENOG4105CEP	NADH dehydrogenase
F0316_04815	ENOG4106M3D	hemolysin
F0316_04825	ENOG4108JA2	transcriptioN-repair coupling factor
F0316_04835	ENOG4105D60	lipoprotein releasing system transmembrane protein
F0316_04840	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
F0316_04845	ENOG4105D60	lipoprotein releasing system transmembrane protein
F0316_04855	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
F0316_04860	ENOG4105BZ1	(ABC) transporter
F0316_04865	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
F0316_04875	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
F0316_04880	ENOG4105ED1	spovr family
F0316_04885	ENOG4106AKX	UPF0229 protein
F0316_04890	ENOG4105CYN	Serine protein kinase
F0316_04895	ENOG4105XWI	UPF0304 protein
F0316_04905	ENOG4105F1A	Pyruvate formate-lyase
F0316_04915	ENOG4108N3W	hemolysin secretion protein
F0316_04925	ENOG4105C6N	Formate acetyltransferase
F0316_04940	ENOG4108JEH	abc transporter atp-binding protein
F0316_04945	ENOG4105E89	ABC transporter
F0316_04950	ENOG4105DSP	amino acid AbC transporter
F0316_04955	ENOG4106YG3	ABC transporter
F0316_04960	ENOG4105CGK	Exodeoxyribonuclease III
F0316_04965	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_04970	ENOG4106428	Protein of unknown function (DUF2496)
F0316_04975	ENOG4108URS	primosomal replication protein n''
F0316_04980	ENOG4105EJ9	Membrane
F0316_04985	ENOG4105DVT	helicase
F0316_04990	ENOG4105ZU8	porin-like protein H
F0316_05005	ENOG4105D58	Diguanylate phosphodiesterase
F0316_05010	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
F0316_05015	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
F0316_05020	ENOG4105C8N	cysteinyl-tRNA synthetase
F0316_05025	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
F0316_05030	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
F0316_05035	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
F0316_05040	ENOG4105C4M	(Ubiquinol oxidase) subunit I
F0316_05045	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
F0316_05055	ENOG4105KJB	cyd operon protein YbgE
F0316_05060	ENOG4107YD3	Thioesterase
F0316_05065	ENOG4105E02	MotA TolQ exbB proton channel
F0316_05070	ENOG4105M8F	Biopolymer transport protein exbD tolR
F0316_05080	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
F0316_05085	ENOG4105KCK	Peptidoglycan-associated lipoprotein
F0316_05095	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
F0316_05105	ENOG4105BZU	Histidine kinase
F0316_05110	ENOG4108RNS	Exports L-alanine (By similarity)
F0316_05115	ENOG4105C26	Dehydrogenase
F0316_05120	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
F0316_05125	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
F0316_05135	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
F0316_05185	ENOG4108YGG	dna repair protein
F0316_05195	ENOG4108478	ec 3.2.1.18
F0316_05200	ENOG4105CE4	GlcNAc 6-P deacetylase
F0316_05205	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
F0316_05210	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
F0316_05220	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
F0316_05225	ENOG41069H7	transport system small permease component
F0316_05230	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
F0316_05240	ENOG4105QEK	Transcriptional regulator
F0316_05245	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
F0316_05260	ENOG4107VGF	ig domain protein group 2 domain protein
F0316_05280	ENOG4107S9D	Alpha beta hydrolase
F0316_05290	ENOG4105F88	accessory colonization factor AcfD
F0316_05325	ENOG4108RS6	transposase
F0316_05330	ENOG4108J1Q	
F0316_05430	ENOG4105UYK	outer membrane protein a
F0316_05455	ENOG4108TU9	TRANSCRIPTIONal
F0316_05470	ENOG41075IY	surface presentation of antigens protein SpaP
F0316_05485	ENOG4105K44	type iii secretion
F0316_05550	ENOG4105DFP	Integrase
F0316_05565	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
F0316_05575	ENOG4105DY2	Paraquat-inducible protein b
F0316_05580	ENOG4105F1S	paraquat-inducible protein a
F0316_05585	ENOG4108R86	Transcriptional regulator
F0316_05590	ENOG4105C26	Dehydrogenase
F0316_05595	ENOG4105MTM	Protein of unknown function (DUF1496)
F0316_05605	ENOG41067SE	Tetr family transcriptional regulator
F0316_05610	ENOG4107QPN	acyl-Coa dehydrogenase
F0316_05620	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
F0316_05625	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
F0316_05630	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
F0316_05640	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
F0316_05645	ENOG4105RKX	Protein of unknown function (DUF2498)
F0316_05650	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
F0316_05655	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
F0316_05660	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
F0316_05680	ENOG4105HP8	regulator of competence-specific genes
F0316_05685	ENOG4105ETE	Transcriptional regulator (LacI family
F0316_05700	ENOG4106WF9	DNA-binding transcriptional regulator TorR
F0316_05705	ENOG4107S90	membrAne
F0316_05710	ENOG4106371	Methyltransferase
F0316_05715	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
F0316_05720	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
F0316_05725	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
F0316_05730	ENOG4107QW4	alcohol dehydrogenase
F0316_05735	ENOG4105CF7	AraC family transcriptional regulator
F0316_05745	ENOG4105EW9	transcriptional regulator AsnC family
F0316_05750	ENOG4108VP3	Lysine exporter protein (LysE YggA)
F0316_05755	ENOG4105CCT	upf0313 protein
F0316_05780	ENOG4105DZ2	Transcriptional regulator
F0316_05785	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
F0316_05795	ENOG4105K9H	YciI-like protein
F0316_05800	ENOG4105NAU	thioesterase Superfamily protein
F0316_05805	ENOG4107835	probably involved in intracellular septation (By similarity)
F0316_05815	ENOG4105GFG	DUF218 domain
F0316_05820	ENOG4108535	NAD dependent epimerase/dehydratase family
F0316_05835	ENOG4105TMB	Formate nitrite transporter
F0316_05855	ENOG4107QY8	reductase
F0316_05870	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
F0316_05885	ENOG4108JQ2	peptide transport system atp-binding protein
F0316_05890	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
F0316_05895	ENOG4108EU3	peptide transport system, permease
F0316_05900	ENOG4108I5W	peptide transport system, permease protein
F0316_05905	ENOG4105DEF	Extracellular solute-binding protein, family 5
F0316_05910	ENOG4105E51	psp operon transcriptional activator
F0316_05915	ENOG41087YS	Phage shock protein A
F0316_05930	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
F0316_05945	ENOG4108R3E	Dna-3-methyladenine glycosylase i
F0316_05950	ENOG4105C28	cystathionine
F0316_05960	ENOG4105C8J	)-transporter
F0316_05965	ENOG4108W1A	pseudouridine synthase
F0316_05970	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
F0316_05975	ENOG4108VGW	abc transporter atp-binding protein
F0316_05980	ENOG4105CXZ	ABC transporter, permease
F0316_05985	ENOG4105VNH	ABC transporter solute-binding protein
F0316_05995	ENOG4105XZD	Fe-S protein
F0316_06005	ENOG4107QWP	ABC-2 type transporter
F0316_06010	ENOG4105CJ1	ABC, transporter
F0316_06020	ENOG4105C44	Serine transporter
F0316_06030	ENOG4105CJW	magnesium transporter
F0316_06035	ENOG4105BZU	Histidine kinase
F0316_06040	ENOG4105BZU	Histidine kinase
F0316_06050	ENOG4105KXC	Collagenase
F0316_06080	ENOG4108N3W	hemolysin secretion protein
F0316_06100	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
F0316_06105	ENOG4105BZU	Histidine kinase
F0316_06120	ENOG4105CFI	type iii restriction protein res subunit
F0316_06125	ENOG4105I08	Pseudouridine synthase
F0316_06130	ENOG4105C2C	drug resistance transporter, Bcr CflA
F0316_06140	ENOG4105CGD	Nad-dependent epimerase dehydratase
F0316_06145	ENOG4105UQX	Mate efflux family protein
F0316_06150	ENOG4108I0Y	(ABC) transporter
F0316_06165	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
F0316_06180	ENOG4105E3Q	saccharopine dehydrogenase
F0316_06185	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
F0316_06190	ENOG4105CDV	Ompa motb domain protein
F0316_06195	ENOG4105DFG	type I secretion outer membrane protein
F0316_06240	ENOG4105VNT	transposase (IS4 family) protein
F0316_06255	ENOG4105F04	LysR family Transcriptional regulator
F0316_06265	ENOG4108VKG	metal-dependent hydrolase
F0316_06270	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
F0316_06280	ENOG41090FY	type IV pilus biogenesis stability protein PilW
F0316_06285	ENOG4105CVG	Homoserine O-transsuccinylase
F0316_06305	ENOG4107V40	secretion protein, HlyD family
F0316_06320	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
F0316_06325	ENOG4106YYS	transcriptional regulatory protein
F0316_06335	ENOG4107R88	Chemotaxis protein (CheV)
F0316_06355	ENOG4105BZU	Histidine kinase
F0316_06380	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
F0316_06385	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
F0316_06390	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
F0316_06395	ENOG4105BZU	Histidine kinase
F0316_06400	ENOG4105BZU	Histidine kinase
F0316_06410	ENOG4105C7K	acetolactate synthase
F0316_06415	ENOG4107FQX	Alpha-acetolactate decarboxylase
F0316_06430	ENOG4108TWJ	NADH dehydrogenase subunit 5
F0316_06435	ENOG4105DUM	transcriptional regulator, lysR family
F0316_06455	ENOG4105V0I	UPF0267 protein
F0316_06470	ENOG4105C9Q	fumarate hydratase class II
F0316_06480	ENOG4105C4M	(Ubiquinol oxidase) subunit I
F0316_06485	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
F0316_06490	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
F0316_06495	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
F0316_06500	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
F0316_06510	ENOG4107QZV	Type I secretion membrane fusion protein
F0316_06525	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
F0316_06530	ENOG4105CS2	ec 3.2.1.21
F0316_06535	ENOG4105DDV	Transcriptional regulator (LacI family
F0316_06540	ENOG4105M4H	endoribonuclease L-psp
F0316_06545	ENOG4105XEP	YhcH YjgK YiaL family protein
F0316_06550	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
F0316_06555	ENOG4105E98	transcriptional regulator DeoR family
F0316_06560	ENOG4108IJ9	(ABC) transporter
F0316_06565	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
F0316_06570	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
F0316_06595	ENOG4109015	Biopolymer transport protein exbD tolR
F0316_06600	ENOG41067XB	TonB family
F0316_06620	ENOG4107QI1	Mate efflux family protein
F0316_06630	ENOG4105FGM	Fructosamine kinase
F0316_06640	ENOG4107TT5	NLP P60 protein
F0316_06645	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_06655	ENOG4106IUH	DTW domain containing protein
F0316_06660	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
F0316_06670	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
F0316_06675	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
F0316_06680	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
F0316_06685	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
F0316_06695	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F0316_06700	ENOG4105BZU	Histidine kinase
F0316_06705	ENOG4105C5H	ABC transporter
F0316_06710	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
F0316_06730	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
F0316_06740	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
F0316_06745	ENOG4105QAX	Iron-sulfur
F0316_06760	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
F0316_06770	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
F0316_06785	ENOG4105QNR	S1 RNA binding domain protein
F0316_06790	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
F0316_06795	ENOG4105DY2	Paraquat-inducible protein b
F0316_06800	ENOG4105H2K	paraquat-inducible protein a
F0316_06805	ENOG4105BZ1	(ABC) transporter
F0316_06810	ENOG4108ZGC	gaf domain protein
F0316_06815	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
F0316_06820	ENOG4105CN1	protease
F0316_06830	ENOG4105CD8	aminopeptidase N
F0316_06840	ENOG4105C7I	Dehydrogenase
F0316_06845	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
F0316_06850	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
F0316_06855	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
F0316_06865	ENOG4105C5H	ABC transporter
F0316_06880	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
F0316_06885	ENOG4105DAN	ATP-dependent protease
F0316_06890	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
F0316_06905	ENOG4105EUK	rtx toxin RtxA
F0316_06910	ENOG4108RC6	RTX toxin
F0316_06935	ENOG4105BZU	Histidine kinase
F0316_06950	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
F0316_06965	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
F0316_06975	ENOG4105C59	p-type ATPase
F0316_06990	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
F0316_06995	ENOG4105Q9Y	Universal stress protein
F0316_07000	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
F0316_07020	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
F0316_07025	ENOG4105F38	ABC transporter, permease
F0316_07030	ENOG4105D38	putrescine abc transporter
F0316_07035	ENOG4107RUE	extracellular solute-binding protein family 1
F0316_07040	ENOG4107RUE	extracellular solute-binding protein family 1
F0316_07055	ENOG4105BZG	amino acid carrier protein
F0316_07060	ENOG410829K	Lysine exporter protein (Lyse ygga)
F0316_07080	ENOG4105CS6	Rhs element vgr protein
F0316_07085	ENOG4108WC9	type VI secretion system effector, hcp1 family
F0316_07090	ENOG4105CTD	carboxy-peptidase
F0316_07095	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_07100	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
F0316_07105	ENOG4105CW7	secretion protein, HlyD family
F0316_07110	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
F0316_07120	ENOG4105C1J	atp-dependent rna helicase
F0316_07125	ENOG4107SDU	Methyl-accepting chemotaxis
F0316_07130	ENOG4108N3W	hemolysin secretion protein
F0316_07135	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_07140	ENOG4108V3W	Chemotaxis protein, CheW
F0316_07145	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
F0316_07155	ENOG4105BZU	Histidine kinase
F0316_07160	ENOG4105CBS	Chea signal transduction histidine kinase
F0316_07165	ENOG4105CBS	Chea signal transduction histidine kinase
F0316_07175	ENOG4108VYJ	response regulator receiver protein
F0316_07180	ENOG4108NVR	Methyl-accepting chemotaxis
F0316_07185	ENOG4105KPY	Small multidrug resistance protein
F0316_07190	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
F0316_07195	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
F0316_07200	ENOG4105EJC	lysr family transcriptional regulator
F0316_07210	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
F0316_07215	ENOG4105R8A	Heat shock protein
F0316_07225	ENOG4105CQ7	ATP-dependent helicase
F0316_07250	ENOG4105BZU	Histidine kinase
F0316_07265	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
F0316_07270	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
F0316_07275	ENOG4105BZU	Histidine kinase
F0316_07285	ENOG4105BZU	Histidine kinase
F0316_07305	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
F0316_07310	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
F0316_07315	ENOG410667J	hydrolase
F0316_07325	ENOG4107QXX	ABC transporter
F0316_07330	ENOG4105EZ7	amino acid ABC transporter
F0316_07335	ENOG4105DRP	amino acid AbC transporter
F0316_07340	ENOG4105CDA	abc transporter atp-binding protein
F0316_07345	ENOG4108MN8	Membrane
F0316_07350	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
F0316_07355	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
F0316_07360	ENOG4105DR4	Methyltransferase
F0316_07365	ENOG4106TD9	Diguanylate cyclase
F0316_07380	ENOG4105BZU	Histidine kinase
F0316_07385	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
F0316_07390	ENOG4108RXX	maleylacetoacetate isomerase
F0316_07400	ENOG4105F1J	Homogentisate 1,2-dioxygenase
F0316_07405	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
F0316_07410	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
F0316_07425	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
F0316_07430	ENOG4105C7F	AcnD-accessory protein PrpF
F0316_07435	ENOG4108I0Z	Aconitate hydratase
F0316_07440	ENOG4105BZN	citrate synthase
F0316_07445	ENOG4105CR4	methylisocitrate lyase
F0316_07450	ENOG41073TP	transcriptional regulator
F0316_07485	ENOG4105EFX	secretion protein, HlyD family
F0316_07500	ENOG4107SDZ	Galactoside transport system permease protein mglC
F0316_07505	ENOG4105C2J	ABC transporter
F0316_07535	ENOG4107EXC	regulatoR
F0316_07540	ENOG4105EB3	Histidine kinase
F0316_07545	ENOG4105RW8	MltA-interacting MipA family protein
F0316_07550	ENOG4108MJ5	VirK protein
F0316_07555	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F0316_07560	ENOG4105BZU	Histidine kinase
F0316_07565	ENOG4105C8P	)-transporter
F0316_07570	ENOG4108NVR	Methyl-accepting chemotaxis
F0316_07575	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
F0316_07595	ENOG4105D9U	N-acetyltransferase
F0316_07600	ENOG4108JU8	Transcriptional regulator
F0316_07610	ENOG4105CM6	amino acid regulated cytosolic protein
F0316_07625	ENOG4105CRQ	synthase (Component I)
F0316_07630	ENOG4105P8F	nudix hydrolase
F0316_07635	ENOG4105C44	Serine transporter
F0316_07640	ENOG4105EJQ	L-serine dehydratase
F0316_07645	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
F0316_07650	ENOG4108NVR	Methyl-accepting chemotaxis
F0316_07655	ENOG4105C5S	asparaginyl-tRNA synthetase
F0316_07665	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
F0316_07670	ENOG4105CGF	Aromatic amino acid aminotransferase
F0316_07685	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_07690	ENOG4105DJ9	glucan biosynthesis protein
F0316_07695	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
F0316_07700	ENOG41060NJ	transcriptional regulator
F0316_07705	ENOG410901P	UPF0249 protein
F0316_07710	ENOG4105F8D	glycoside hydrolase family 4
F0316_07715	ENOG4105VCP	PTS System
F0316_07725	ENOG4105VZJ	PTS System
F0316_07735	ENOG4105C94	Transporter
F0316_07740	ENOG41067TZ	transcriptional regulator, MarR family
F0316_07760	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
F0316_07770	ENOG4105CH5	extracellular solute-binding protein, family 7
F0316_07785	ENOG4105C5X	domain protein
F0316_07790	ENOG4105EAQ	(twin-arginine translocation) pathway signal
F0316_07820	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
F0316_07830	ENOG4105S8Q	sugar efflux transporter
F0316_07840	ENOG4105C72	UPF0176 protein
F0316_07845	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F0316_07850	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
F0316_07855	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
F0316_07860	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
F0316_07865	ENOG4107QK7	reductase
F0316_07895	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_07910	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
F0316_07915	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
F0316_07930	ENOG4108YZT	Adenosylcobinamide kinase
F0316_07935	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
F0316_07940	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
F0316_07945	ENOG4105E0X	reductase
F0316_07950	ENOG4108ETY	sodium dicarboxylate symporter
F0316_07955	ENOG4105CJB	Exodeoxyribonuclease I
F0316_07965	ENOG41067MG	lrgb family
F0316_07970	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
F0316_07990	ENOG4105FQ6	thiopurine methyltransferase
F0316_08005	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
F0316_08010	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
F0316_08015	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
F0316_08025	ENOG4105BZU	Histidine kinase
F0316_08055	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
F0316_08060	ENOG4105WH1	Two component transcriptional regulator luxr family
F0316_08065	ENOG4105CQ2	DNA polymerase
F0316_08070	ENOG4105BZU	Histidine kinase
F0316_08080	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
F0316_08095	ENOG4105CZE	histidine utilization repressor
F0316_08100	ENOG4105CI2	imidazolone-5-propionate hydrolase
F0316_08105	ENOG41088SP	formiminoglutamate hydrolase
F0316_08110	ENOG4105CGP	Urocanate hydratase
F0316_08115	ENOG4105C84	Histidine ammonia-lyase
F0316_08125	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
F0316_08135	ENOG4105CQB	FAD linked oxidase domain protein
F0316_08150	ENOG4108ZG0	Ompa motb domain protein
F0316_08170	ENOG4105C8V	SAICAR synthetase
F0316_08180	ENOG4107R1I	NAD-dependent malic enzyme
F0316_08190	ENOG4107GZ4	SanA protein
F0316_08195	ENOG4105BZU	Histidine kinase
F0316_08210	ENOG4105C3M	thioredoxin reductase
F0316_08215	ENOG4108JJ9	ABC, transporter
F0316_08220	ENOG4108JJ8	(ABC) transporter
F0316_08225	ENOG4105FE9	pseudouridine synthase
F0316_08230	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
F0316_08235	ENOG4105DB7	PHP domain protein
F0316_08245	ENOG4105CRQ	synthase (Component I)
F0316_08250	ENOG4105DDQ	anthranilate synthase
F0316_08255	ENOG4108I0Q	anthranilate phosphoribosyltransferase
F0316_08260	ENOG4105DK0	Indole-3-glycerol phosphate synthase
F0316_08265	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
F0316_08270	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
F0316_08275	ENOG4105CK2	sodium dicarboxylate symporter
F0316_08280	ENOG4107104	thymidine kinase
F0316_08285	ENOG4105C9M	aspartyl-trna synthetase
F0316_08290	ENOG41081XQ	Conserved Protein
F0316_08295	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
F0316_08300	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
F0316_08305	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
F0316_08320	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
F0316_08330	ENOG4105CUX	Signal transduction histidine kinase
F0316_08355	ENOG4105DWU	Membrane
F0316_08365	ENOG4105DY8	decarboxylase
F0316_08370	ENOG4106KNT	transcriptional regulator
F0316_08375	ENOG4108EKI	Dehydrogenase
F0316_08380	ENOG41090BQ	Glutaredoxin
F0316_08390	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F0316_08395	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
F0316_08400	ENOG4105VEQ	Cold shock protein
F0316_08410	ENOG4108R99	pseudouridine synthase
F0316_08415	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
F0316_08420	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
F0316_08425	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
F0316_08430	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
F0316_08435	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
F0316_08440	ENOG4105CIH	Imidazole acetol-phosphate transaminase
F0316_08445	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
F0316_08450	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
F0316_08455	ENOG4107S6Z	Na H antiporter
F0316_08465	ENOG4107RE1	Inosine-guanosine kinase
F0316_08470	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
F0316_08475	ENOG41075W9	High frequency lysogenization protein HflD homolog
F0316_08480	ENOG4107QTF	adenylosuccinate lyase
F0316_08490	ENOG4105RHG	
F0316_08500	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
F0316_08515	ENOG4107FW0	short-chain dehydrogenase reductase
F0316_08525	ENOG4105D0M	Protease HtpX homolog
F0316_08535	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
F0316_08540	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
F0316_08545	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
F0316_08550	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
F0316_08555	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
F0316_08560	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
F0316_08565	ENOG4105D1H	recombination factor protein RarA
F0316_08575	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
F0316_08580	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
F0316_08585	ENOG4105BZU	Histidine kinase
F0316_08590	ENOG4108JJB	ABC transporter
F0316_08595	ENOG4105C7J	ABC transporter, permease
F0316_08605	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
F0316_08610	ENOG4105PQ6	UPF0208 membrane protein
F0316_08615	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
F0316_08620	ENOG4108DNC	Involved in acetate metabolism (By similarity)
F0316_08625	ENOG4105CHF	Glutathione S-transferase
F0316_08630	ENOG4108JQ7	(ABC) transporter
F0316_08635	ENOG4105C3U	ABC transporter
F0316_08640	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F0316_08645	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
F0316_08650	ENOG4107QSI	ABC, transporter
F0316_08665	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F0316_08670	ENOG4105BZU	Histidine kinase
F0316_08675	ENOG4105BZU	Histidine kinase
F0316_08680	ENOG4105BZU	Histidine kinase
F0316_08690	ENOG4107YTP	response regulator receiver protein
F0316_08705	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
F0316_08725	ENOG4108V1U	phospholipid-binding protein
F0316_08750	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
F0316_08755	ENOG41082YX	Transcriptional regulator, arsr family
F0316_08765	ENOG4105BZU	Histidine kinase
F0316_08785	ENOG4105C29	acyl-CoA thioesterase
F0316_08790	ENOG4108XM1	transcriptional regulator AsnC family
F0316_08800	ENOG4105ERU	peptidase
F0316_08805	ENOG4105UBK	short-chain dehydrogenase reductase
F0316_08820	ENOG4105KRS	Proteinase inhibitor
F0316_08825	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
F0316_08830	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
F0316_08835	ENOG4107QMP	dna polymerase iii subunits gamma and tau
F0316_08840	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
F0316_08845	ENOG4105WD1	Membrane
F0316_08855	ENOG4105I93	response regulator
F0316_08860	ENOG4105EJC	lysr family transcriptional regulator
F0316_08865	ENOG41069NU	Nitroreductase
F0316_08870	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
F0316_08875	ENOG4105CHU	acetyl-coa acetyltransferase
F0316_08895	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
F0316_08900	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
F0316_08910	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
F0316_08915	ENOG4108GAE	asmA family
F0316_08920	ENOG4105DBI	uridine monophosphokinase
F0316_08930	ENOG4105D1F	ATP-binding protein
F0316_08935	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
F0316_08945	ENOG4108I5U	Uridine phosphorylase
F0316_08965	ENOG4105BZU	Histidine kinase
F0316_08970	ENOG4108ZAF	Molybdopterin
F0316_08975	ENOG4105M00	molybdopterin converting factor, subunit 1
F0316_08980	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
F0316_08985	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
F0316_08990	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
F0316_08995	ENOG4105CHW	UPF0052 protein
F0316_09005	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F0316_09015	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
F0316_09030	ENOG4108R3D	Electron transport complex
F0316_09040	ENOG4105D6A	Electron transport complex
F0316_09045	ENOG4108UQQ	Electron transport complex
F0316_09050	ENOG4105DZB	Electron transport complex
F0316_09055	ENOG4105CSM	endonuclease III
F0316_09060	ENOG4108UYE	Lactoylglutathione lyase
F0316_09065	ENOG4106WH9	Protein of unknown function (DUF2753)
F0316_09070	ENOG4105EIY	sodium-type flagellar protein motY
F0316_09075	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
F0316_09080	ENOG4105D3Y	Na H antiporter
F0316_09085	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
F0316_09090	ENOG4105E96	Colicin v production protein
F0316_09095	ENOG4108S3P	Sporulation domain protein
F0316_09100	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
F0316_09105	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
F0316_09110	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
F0316_09120	ENOG4105CX6	glutaminyL-tRNA synthetase
F0316_09125	ENOG4105CI1	PTS System
F0316_09130	ENOG4105CE4	GlcNAc 6-P deacetylase
F0316_09135	ENOG4105E2R	ROK family
F0316_09140	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
F0316_09145	ENOG4105CAQ	asparagine synthetase
F0316_09150	ENOG4105MDZ	Transcriptional activator rfaH
F0316_09155	ENOG4105DUX	Transporter
F0316_09160	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
F0316_09165	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
F0316_09170	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
F0316_09175	ENOG4108TU9	TRANSCRIPTIONal
F0316_09190	ENOG4108RE9	Phosphodiesterase
F0316_09195	ENOG4105ECP	epimerase
F0316_09200	ENOG4105E1F	short-chain dehydrogenase reductase
F0316_09210	ENOG4107QR8	Thioredoxin
F0316_09215	ENOG4107QX8	SPFH domain, Band 7 family protein
F0316_09220	ENOG4105G5H	Membrane
F0316_09225	ENOG4108Z6Z	Transcriptional regulator
F0316_09240	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
F0316_09245	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
F0316_09250	ENOG4105EXN	Sulfate transport protein CysZ
F0316_09255	ENOG4105C6T	cysteine synthase
F0316_09265	ENOG4105KZ7	phosphocarrier protein hpr
F0316_09275	ENOG4105C5Y	PTS System
F0316_09280	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
F0316_09285	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
F0316_09290	ENOG4105C9A	Phoh family
F0316_09295	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
F0316_09300	ENOG4108JU5	Magnesium and cobalt efflux protein
F0316_09305	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
F0316_09310	ENOG4107PAI	alpha helical protein
F0316_09315	ENOG4105C8T	Leucyl-tRNA synthetase
F0316_09320	ENOG4108U2H	Rare lipoprotein B
F0316_09325	ENOG4105DJF	DNA polymerase III, delta' subunit
F0316_09330	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
F0316_09335	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
F0316_09340	ENOG4105CJN	penicillin-binding protein
F0316_09345	ENOG4105CNI	cell division protein FtsW
F0316_09350	ENOG4105K6T	rare lipoprotein A
F0316_09355	ENOG4105DZ1	carboxypeptidase
F0316_09360	ENOG4108Z43	UPF0250 protein
F0316_09365	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
F0316_09370	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
F0316_09380	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
F0316_09400	ENOG4105D75	Capsular exopolysaccharide family
F0316_09405	ENOG4105DAY	polysaccharide export protein
F0316_09415	ENOG4105D3Q	Sugar transferase
F0316_09430	ENOG4108MA4	Peptidase M66
F0316_09445	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
F0316_09455	ENOG4105Q84	sucrose synthase
F0316_09465	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
F0316_09490	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
F0316_09495	ENOG4107ZF2	Phosphatase
F0316_09500	ENOG4105BZS	acriflavin resistance protein
F0316_09525	ENOG4105CG3	alpha amylase, catalytic region
F0316_09530	ENOG4105C5Y	PTS System
F0316_09535	ENOG4105D4X	repressor
F0316_09540	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
F0316_09545	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
F0316_09550	ENOG4108UMI	ABC transporter, permease
F0316_09555	ENOG4105D01	(LipO)protein
F0316_09560	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
F0316_09565	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
F0316_09570	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
F0316_09580	ENOG4105BZU	Histidine kinase
F0316_09585	ENOG4105EWT	decarboxylase family
F0316_09590	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
F0316_09595	ENOG4105M08	Membrane
F0316_09600	ENOG4105ETT	transcriptional Regulator, LysR family
F0316_09610	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
F0316_09615	ENOG4106VK6	Flagellar motor protein
F0316_09620	ENOG4105E14	MotA TolQ exbB proton channel
F0316_09630	ENOG4105CTB	Polyprenyl synthetase
F0316_09635	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
F0316_09640	ENOG4105DR9	pseudouridine synthase
F0316_09645	ENOG4105WP7	tRNA pseudouridine synthase C
F0316_09660	ENOG4108428	Inherit from COG: -acetyltransferase
F0316_09670	ENOG4108UPT	UPF0178 protein
F0316_09675	ENOG4105CFC	Transporter
F0316_09685	ENOG4105NRA	50s ribosomal protein l31 type b
F0316_09690	ENOG4108R96	Methyltransferase, YaeB family
F0316_09695	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
F0316_09715	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
F0316_09725	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
F0316_09730	ENOG4108Z6B	deaminase
F0316_09735	ENOG4105CFC	Transporter
F0316_09770	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
F0316_09775	ENOG4105CFG	Acts as a chaperone (By similarity)
F0316_09780	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F0316_09785	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
F0316_09790	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
F0316_09795	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
F0316_09800	ENOG4105VDB	UPF0125 protein
F0316_09805	ENOG4108Z1B	Cyclase dehydrase
F0316_09810	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
F0316_09870	ENOG4105DZ0	fad dependent oxidoreductase
F0316_09880	ENOG4108Z4U	Ferredoxin
F0316_09895	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
F0316_09900	ENOG4105YGP	holo-ACP synthase CitX
F0316_09905	ENOG4105CHY	citrate lyase, alpha
F0316_09910	ENOG4105CI0	Citrate lyase
F0316_09915	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
F0316_09920	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
F0316_09935	ENOG4107QSA	Oxaloacetate decarboxylase
F0316_09940	ENOG4105D9Q	decarboxylase (Beta subunit)
F0316_09945	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
F0316_09950	ENOG4106YYS	transcriptional regulatory protein
F0316_09970	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
F0316_09975	ENOG4105BZG	amino acid carrier protein
F0316_09980	ENOG4105EUZ	Beta-lactamase domain protein
F0316_09985	ENOG41064T2	transcriptional regulator, lysR family
F0316_09995	ENOG4105E0A	ABC, transporter
F0316_10000	ENOG4105TVJ	transport system, permease
F0316_10005	ENOG4105DQ5	transport system permease protein
F0316_10010	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
F0316_10020	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
F0316_10025	ENOG4105E4F	Isochorismate synthase
F0316_10030	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
F0316_10035	ENOG4105WQI	isochorismatase
F0316_10040	ENOG4106HK8	GPR1 FUN34 yaaH family protein
F0316_10050	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
F0316_10055	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
F0316_10060	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
F0316_10075	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
F0316_10080	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
F0316_10085	ENOG4105N21	Membrane
F0316_10090	ENOG4105CUT	histidyl-tRNA synthetase
F0316_10095	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
F0316_10100	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
F0316_10110	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
F0316_10115	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
F0316_10120	ENOG4105WVQ	Fe-S assembly protein IscX
F0316_10125	ENOG4108ZIT	Ferredoxin, 2FE-2S
F0316_10140	ENOG4108Z4V	iron-sulfur cluster assembly
F0316_10145	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
F0316_10155	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
F0316_10160	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
F0316_10165	ENOG4105ECY	inositol monophosphatase
F0316_10170	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
F0316_10175	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
F0316_10180	ENOG4105VIE	preprotein translocase, subunit YajC
F0316_10185	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
F0316_10195	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
F0316_10200	ENOG4105W87	Cbs domain
F0316_10205	ENOG4108I9X	Isocitrate lyase
F0316_10210	ENOG4107QP3	malate synthase g
F0316_10215	ENOG4105C5Q	Transcriptional regulator
F0316_10220	ENOG4105D3R	alkyl hydroperoxide reductase
F0316_10225	ENOG4106N3A	copper homeostasis protein cutc
F0316_10230	ENOG4105CSR	polyphosphate kinase 2
F0316_10240	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
F0316_10245	ENOG4105E2Z	phosphate ABC transporter (Permease
F0316_10250	ENOG4105C8U	phosphate abc transporter
F0316_10255	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
F0316_10260	ENOG4105C9X	ppx gppa phosphatase
F0316_10270	ENOG4105BZU	Histidine kinase
F0316_10275	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
F0316_10280	ENOG4105DH7	May be involved in recombination (By similarity)
F0316_10285	ENOG4105CFP	Peptidase U32
F0316_10290	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
F0316_10335	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F0316_10340	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
F0316_10345	ENOG4105C34	Pseudouridine synthase
F0316_10350	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0316_10355	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
F0316_10365	ENOG4107XW0	Spermidine putrescine ABC transporter periplasmic spermidine putrescine-binding protein
F0316_10370	ENOG4108K0B	C-di-gmp phosphodiesterase
F0316_10375	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
F0316_10380	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
F0316_10385	ENOG4107SC1	transglycosylase
F0316_10390	ENOG4105C5H	ABC transporter
F0316_10405	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
F0316_10410	ENOG4108HRK	Histidine kinase
F0316_10415	ENOG4108NEV	two component transcriptional regulator, LytTR family
F0316_10420	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
F0316_10425	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
F0316_10430	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F0316_10450	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
F0316_10455	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
F0316_10460	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
F0316_10465	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
F0316_10470	ENOG4105DTN	riboflavin biosynthesis protein ribF
F0316_10475	ENOG4105CJR	Integral membrane protein (MviN
F0316_10480	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
F0316_10485	ENOG41080HT	Transcriptional regulator, arsr family
F0316_10490	ENOG41063Z6	transcriptional regulator, lysR family
F0316_10500	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
F0316_10505	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
F0316_10510	ENOG4105HF0	Membrane
F0316_10515	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
F0316_10520	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
F0316_10525	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
F0316_10530	ENOG4105CPC	Aldo Keto reductase
F0316_10540	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F0316_10545	ENOG4105CRK	lysyL-tRNA synthetase
F0316_10555	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
F0316_10560	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
F0316_10565	ENOG4105C1J	atp-dependent rna helicase
F0316_10570	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
F0316_10575	ENOG4105BZU	Histidine kinase
F0316_10590	ENOG4108YYD	acetyltransferase
F0316_10595	ENOG4105XPQ	lipid carrier protein
F0316_10600	ENOG4105BZU	Histidine kinase
F0316_10605	ENOG4105CFP	Peptidase U32
F0316_10610	ENOG4106RZ4	Peptidase U32
F0316_10625	ENOG4105RT1	May be involved in cell division (By similarity)
F0316_10630	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
F0316_10635	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
F0316_10640	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
F0316_10645	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
F0316_10650	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
F0316_10655	ENOG4105CHV	Transcription elongation factor NusA
F0316_10660	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
F0316_10685	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
F0316_10690	ENOG4105EEI	dihydropteroate synthase
F0316_10695	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
F0316_10700	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
F0316_10705	ENOG4105HBR	Rna-binding protein
F0316_10710	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
F0316_10720	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
F0316_10725	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
F0316_10730	ENOG4105DR5	peptidase
F0316_10735	ENOG4105BZS	acriflavin resistance protein
F0316_10745	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
F0316_10750	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
F0316_10760	ENOG4105IPI	Membrane
F0316_10765	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
F0316_10770	ENOG4105BZU	Histidine kinase
F0316_10780	ENOG4107QRA	Extracellular solute-binding protein, family 5
F0316_10790	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F0316_10795	ENOG4105C3U	ABC transporter
F0316_10800	ENOG4108JQ7	(ABC) transporter
F0316_10810	ENOG4105RD7	BadF BadG BcrA BcrD
F0316_10815	ENOG4105E2D	ec 3.2.1.52
F0316_10820	ENOG4105E2V	Glycosyltransferase 36
F0316_10830	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
F0316_10850	ENOG4108YZA	Nitrogen regulatory protein pii
F0316_10855	ENOG4105XTV	UPF0231 protein
F0316_10860	ENOG4107QIJ	Aconitate hydratase 2
F0316_10865	ENOG4105D78	K07001 NTE family protein
F0316_10870	ENOG4105BZ4	penicillin-binding protein
F0316_10875	ENOG4105CQ7	ATP-dependent helicase
F0316_10885	ENOG4105PW4	Sugar fermentation stimulation protein homolog
F0316_10890	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F0316_10895	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
F0316_10900	ENOG4105DJ0	Poly(A) Polymerase
F0316_10905	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F0316_10910	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
F0316_10915	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
F0316_10920	ENOG4105E3A	(ABC) transporter
F0316_10925	ENOG4105DA5	(ABC) transporter
F0316_10930	ENOG4105CHH	sulfate transporter
F0316_10935	ENOG41077A9	carbonic anhydrase
F0316_10940	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
F0316_10945	ENOG410630P	Transcriptional regulator
F0316_10955	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
F0316_10960	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
F0316_10965	ENOG41082RQ	UPF0102 protein
F0316_10970	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
F0316_10975	ENOG4105W4M	Transport-associated protein
F0316_10980	ENOG4105KB2	stringent starvation protein b
F0316_10985	ENOG4107MKT	Stringent starvation protein a
F0316_10990	ENOG4105EIX	cytochrome c1
F0316_10995	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
F0316_11000	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
F0316_11005	ENOG4108UJD	30S ribosomal protein S9
F0316_11010	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
F0316_11015	ENOG4105D6Z	AFG1 family ATPase
F0316_11025	ENOG4105C0H	protease
F0316_11030	ENOG4105C0H	protease
F0316_11035	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
F0316_11040	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
F0316_11045	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
F0316_11050	ENOG4105K5M	30s ribosomal protein S16
F0316_11055	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F0316_11060	ENOG4106KVJ	cytochrome C assembly protein
F0316_11065	ENOG4108JU6	CBS domain protein
F0316_11070	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
F0316_11075	ENOG4105D9M	gamma-glutamylcysteine synthetase
F0316_11085	ENOG4105W39	Membrane
F0316_11095	ENOG4105D9Q	decarboxylase (Beta subunit)
F0316_11100	ENOG4107QSA	Oxaloacetate decarboxylase
F0316_11150	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
F0316_11155	ENOG4105CFH	Aspartokinase
F0316_11160	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
F0316_11165	ENOG4105Y3E	Modulates RecA activity (By similarity)
F0316_11170	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
F0316_11180	ENOG4108IJ6	ABC transporter
F0316_11185	ENOG4105ECW	sulfate abc transporter
F0316_11190	ENOG4108I5D	sulfate abc transporter
F0316_11195	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
F0316_11200	ENOG4105C6T	cysteine synthase
F0316_11205	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
F0316_11210	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F0316_11215	ENOG4108K5P	(LipO)protein
F0316_11220	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
F0316_11225	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
F0316_11230	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
F0316_11235	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
F0316_11240	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
F0316_11250	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
F0316_11255	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F0316_11260	ENOG4107ZVW	dihydroneopterin aldolase
F0316_11270	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
F0316_11280	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
F0316_11285	ENOG4105VCC	30S ribosomal protein S21
F0316_11290	ENOG4105KTH	gatB Yqey
F0316_11300	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F0316_11390	ENOG4108KZE	transcriptional regulator
F0316_11410	ENOG4105CH5	extracellular solute-binding protein, family 7
F0316_11415	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
F0316_11420	ENOG410804X	Transcriptional regulator
F0316_11425	ENOG4105CA9	Pyruvate kinase
F0316_11430	ENOG4105MPN	Membrane
F0316_11435	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
F0316_11440	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
F0316_11445	ENOG4105D64	Mechanosensitive ion channel
F0316_11455	ENOG4105D2N	Aldolase
F0316_11460	ENOG4105BZA	Phosphoglycerate kinase
F0316_11465	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
F0316_11470	ENOG4105D05	Receptor
F0316_11475	ENOG4108R4R	Iron-regulated virulence regulatory protein
F0316_11480	ENOG4105CV1	Transketolase (EC 2.2.1.1)
F0316_11485	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
F0316_11490	ENOG4105GPY	SprT protein
F0316_11495	ENOG4105RWS	endonuclease I
F0316_11500	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
F0316_11505	ENOG4105D7Z	glutathione synthase
F0316_11510	ENOG4108UJU	UPF0301 protein
F0316_11515	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
F0316_11520	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
F0316_11530	ENOG4105CZX	twitching motility protein
F0316_11535	ENOG4105CZX	twitching motility protein
F0316_11540	ENOG4105DFA	alanine racemase domain protein
F0316_11545	ENOG4105II7	pyrroline-5-carboxylate reductase
F0316_11550	ENOG4108VIA	integral membrane protein
F0316_11555	ENOG4105VZ9	UPF0235 protein
F0316_11565	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
F0316_11570	ENOG4105CSA	Coproporphyrinogen iii oxidase
F0316_11575	ENOG4105CSV	Glutaminase
F0316_11580	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
F0316_11585	ENOG4105CEN	a g-specific adenine glycosylase
F0316_11590	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
F0316_11595	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
F0316_11650	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
F0316_11655	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
F0316_11660	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
F0316_11665	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
F0316_11670	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
F0316_11675	ENOG4105NWN	ApaG protein
F0316_11680	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
F0316_11690	ENOG4107XM3	UPF0442 protein
F0316_11695	ENOG4105DWK	Membrane
F0316_11700	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F0316_11705	ENOG4105K46	50S ribosomal protein l27
F0316_11710	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
F0316_11715	ENOG4105EAH	synthase
F0316_11720	ENOG4105D5Q	Arginine ornithine antiporter
F0316_11725	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
F0316_11730	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
F0316_11750	ENOG41081QV	Universal stress protein
F0316_11775	ENOG4105CEU	Arginine dihydrolase
F0316_11790	ENOG4105QD6	exported protein
F0316_11795	ENOG4105C03	ribonuclease
F0316_11800	ENOG4108Z03	MAF-like protein
F0316_11805	ENOG4105VQ7	Rod shape-determining protein MreD
F0316_11810	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
F0316_11815	ENOG4105DFF	Rod shape-determining protein mreb
F0316_11850	ENOG4105X0D	Fimbrial protein
F0316_11860	ENOG4105D7Q	type ii secretion system
F0316_11865	ENOG4107QHF	type ii secretion system protein e
F0316_11880	ENOG4105E4G	Type IV pilus
F0316_11900	ENOG41062P1	Diguanylate cyclase phosphodiesterase
F0316_11905	ENOG4108UUM	single-stranded DNA-binding protein
F0316_11910	ENOG41086KC	Transcriptional regulator
F0316_11915	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
F0316_11920	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
F0316_11930	ENOG4105C5R	Aminotransferase
F0316_11935	ENOG4105CFH	Aspartokinase
F0316_11940	ENOG4105C3R	Methionine synthase
F0316_11945	ENOG4105EEQ	Na H antiporter
F0316_11975	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
F0316_11980	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
F0316_11985	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
F0316_12005	ENOG4105P4Z	Phage shock protein G
F0316_12010	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
F0316_12015	ENOG4105MYN	Zinc uptake regulation protein
F0316_12030	ENOG4107QP8	phosphohexose isomerase
F0316_12055	ENOG4105DZR	Type I site-specific deoxyribonuclease
F0316_12070	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
F0316_12115	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
F0316_12125	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
F0316_12130	ENOG4105CDU	Replicative dna helicase
F0316_12140	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
F0316_12145	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
F0316_12150	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
F0316_12155	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
F0316_12160	ENOG4108UQY	Iron-storage protein
F0316_12165	ENOG4105W53	bacterioferritin-associated ferredoxin
F0316_12170	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
F0316_12175	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
F0316_12180	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
F0316_12185	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
F0316_12195	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
F0316_12200	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
F0316_12205	ENOG4105WWK	YheO domain protein
F0316_12210	ENOG4108V1T	peptidylprolyl cis-trans isomerase
F0316_12220	ENOG41069P5	Protein slyX homolog
F0316_12230	ENOG4105EPW	hflc protein
F0316_12235	ENOG4107QJR	hflk protein
F0316_12240	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
F0316_12245	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
F0316_12250	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
F0316_12260	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
F0316_12270	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
F0316_12315	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
F0316_12320	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
F0316_12325	ENOG4105DJ4	phosphatidylserine decarboxylase
F0316_12330	ENOG4105C8P	)-transporter
F0316_12340	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
F0316_12350	ENOG4108RS6	transposase
F0316_12355	ENOG41063SB	peptidase
F0316_12365	ENOG41062JF	Transcriptional regulator
F0316_12370	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
F0316_12375	ENOG4105E09	nadh pyrophosphatase
F0316_12380	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
F0316_12385	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F0316_12390	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F0316_12395	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
F0316_12400	ENOG4108VZM	50s ribosomal protein L10
F0316_12405	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
F0316_12410	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
F0316_12415	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
F0316_12420	ENOG4105PM1	preprotein translocase subunit SecE
F0316_12425	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
F0316_12450	ENOG4105CS9	pantothenic acid kinase
F0316_12455	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
F0316_12460	ENOG4105D4A	Cell wall formation (By similarity)
F0316_12470	ENOG4105JIM	Phosphatidylserine synthase
F0316_12535	ENOG4107QK7	reductase
F0316_12545	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
F0316_12555	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
F0316_12560	ENOG4105K63	Thioredoxin
F0316_12565	ENOG4105C1J	atp-dependent rna helicase
F0316_12570	ENOG4105C9X	ppx gppa phosphatase
F0316_12575	ENOG4105BZU	Histidine kinase
F0316_12580	ENOG4105D8G	Major Facilitator superfamily
F0316_12600	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
F0316_12605	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
F0316_12610	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
F0316_12615	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
F0316_12620	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
F0316_12625	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
F0316_12630	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
F0316_12635	ENOG4105DIQ	Transcriptional regulator
F0316_12645	ENOG4105EWV	Sodium calcium exchanger membrane region
F0316_12650	ENOG4105C01	Dihydroxy-acid dehydratase
F0316_12655	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
F0316_12660	ENOG4105C6Z	Gluconate
F0316_12665	ENOG4108UHU	Aldolase
F0316_12670	ENOG4105E0K	tonB-dependent siderophore receptor
F0316_12685	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_12690	ENOG4105CXN	decarboxylase
F0316_12695	ENOG4105D5Q	Arginine ornithine antiporter
F0316_12700	ENOG4108M3R	transcriptional activator CadC
F0316_12705	ENOG4105W1Y	Transcriptional regulator
F0316_12715	ENOG4105DC1	bifunctional purine biosynthesis protein purh
F0316_12720	ENOG4105C12	Phosphoribosylglycinamide synthetase
F0316_12730	ENOG4105K70	DNA-binding protein
F0316_12745	ENOG4105R2J	Conserved Protein
F0316_12750	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
F0316_12755	ENOG4108RG0	uracil-dna glycosylase
F0316_12760	ENOG4105CUY	Mechanosensitive ion channel
F0316_12775	ENOG4105CY0	Metallo-Beta-Lactamase
F0316_12785	ENOG4105ESV	Glycosyl transferase, family 4
F0316_12800	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
F0316_12810	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
F0316_12815	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
F0316_12850	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
F0316_12855	ENOG4105D75	Capsular exopolysaccharide family
F0316_12865	ENOG4105DAY	polysaccharide export protein
F0316_12875	ENOG4108MDC	(LipO)protein
F0316_12885	ENOG4105E3R	(LipO)protein
F0316_12895	ENOG4105D3Q	Sugar transferase
F0316_12955	ENOG4108RT7	Glycosyl transferase, family 2
F0316_12975	ENOG4105EY8	ABC transporter
F0316_12985	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
F0316_12995	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
F0316_13000	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
F0316_13005	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
F0316_13020	ENOG4107T94	Endo-14-beta-xylanase
F0316_13025	ENOG4105XA0	heptosyltransferase ii
F0316_13030	ENOG4108ST3	glycosyltransferase
F0316_13035	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
F0316_13040	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
F0316_13045	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
F0316_13060	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
F0316_13065	ENOG4105DKP	glycosyl transferase, family 9
F0316_13070	ENOG4106WTF	Glycosyl transferase, family 2
F0316_13075	ENOG4105M5K	heptosyltransferase
F0316_13080	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
F0316_13085	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
F0316_13095	ENOG4105W0E	50S ribosomal protein L33
F0316_13100	ENOG4105KDC	50s ribosomal protein l28
F0316_13110	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_13115	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
F0316_13125	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
F0316_13130	ENOG4105D1S	lipid A biosynthesis
F0316_13135	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
F0316_13140	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
F0316_13145	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
F0316_13150	ENOG4105DSJ	YicC domain protein
F0316_13160	ENOG4105C5Y	PTS System
F0316_13165	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F0316_13175	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
F0316_13180	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
F0316_13185	ENOG4105J76	Periplasmic binding protein
F0316_13190	ENOG4105E0A	ABC, transporter
F0316_13195	ENOG4105E0K	tonB-dependent siderophore receptor
F0316_13200	ENOG4105BZ1	(ABC) transporter
F0316_13215	ENOG4105C9U	ATP-dependent DNA helicase RecQ
F0316_13220	ENOG4105FR1	rard protein
F0316_13225	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
F0316_13250	ENOG4105C4R	Atp-dependent dna helicase
F0316_13255	ENOG4105DGW	oligopeptidase A
F0316_13260	ENOG4105D6S	protein involved in catabolism of external DNA
F0316_13265	ENOG4105DC8	reductase
F0316_13275	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F0316_13280	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
F0316_13285	ENOG4105DEF	Extracellular solute-binding protein, family 5
F0316_13330	ENOG4105MPD	Cytochrome
F0316_13335	ENOG4105C4R	Atp-dependent dna helicase
F0316_13340	ENOG4105Y7M	Transcriptional regulator, TetR family
F0316_13345	ENOG410624X	efflux transporter, rnd family, mfp subunit
F0316_13350	ENOG4105BZS	acriflavin resistance protein
F0316_13355	ENOG4105W0Z	cytoplasmic protein
F0316_13360	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
F0316_13365	ENOG4105EMY	transcriptional regulator
F0316_13435	ENOG4108RR8	protoporphyrinogen oxidase
F0316_13440	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
F0316_13445	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
F0316_13450	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
F0316_13455	ENOG4105CHU	acetyl-coa acetyltransferase
F0316_13460	ENOG4105F52	Transcriptional regulator
F0316_13465	ENOG4105CZQ	inner membrane transport protein YdhC
F0316_13475	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
F0316_13480	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
F0316_13485	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
F0316_13490	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
F0316_13495	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F0316_13500	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F0316_13505	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F0316_13510	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
F0316_13515	ENOG410684E	atp synthase
F0316_13520	ENOG4105FA0	parb-like partition protein
F0316_13525	ENOG4107QJE	Chromosome Partitioning Protein
F0316_13530	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
F0316_13535	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
F0316_13545	ENOG4105QTB	Flavodoxin
F0316_13550	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
F0316_13555	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
F0316_13560	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
F0316_13565	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
F0316_13580	ENOG4105E5Q	amino acid AbC transporter
F0316_13585	ENOG4105EAB	amino acid AbC transporter
F0316_13590	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
F0316_13595	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
F0316_13600	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
F0316_13605	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F0316_13620	ENOG4108ZNX	Heat shock protein
F0316_13625	ENOG4105JKW	Valine--pyruvate aminotransferase
F0316_13635	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
F0316_13640	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
F0316_13660	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
F0316_13670	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
F0316_13675	ENOG4105C7B	Threonine dehydratase
F0316_13680	ENOG4105C01	Dihydroxy-acid dehydratase
F0316_13685	ENOG4105CM2	brancheD-chain amino acid aminotransferase
F0316_13700	ENOG4105C0P	Mg chelatase subunit ChlI
F0316_13705	ENOG4106HNH	Acyl-transferase
F0316_13710	ENOG4108Z33	Thiol disulfide Interchange Protein
F0316_13715	ENOG4105E27	serine threonine protein kinase
F0316_13725	ENOG4105PC1	Conserved Protein
F0316_13735	ENOG4108N23	SpoOM-related protein
F0316_13740	ENOG4108UT2	hemolysin iii
F0316_13750	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
F0316_13755	ENOG4105C1A	potassium transporter peripheral membrane
F0316_13760	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
F0316_13765	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
F0316_13770	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
F0316_13775	ENOG4108WZM	domain protein
F0316_13780	ENOG4105C79	DNA protecting protein DprA
F0316_13785	ENOG4108RPN	Protein smg homolog
F0316_13790	ENOG4108WI1	Dna topoisomerase
F0316_13795	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
F0316_13800	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
F0316_13805	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
F0316_13810	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
F0316_13815	ENOG4105E2X	shikimate dehydrogenase
F0316_13825	ENOG4108Z0R	Transferase
F0316_14030	ENOG4105FA0	parb-like partition protein
F0316_14050	ENOG4105KCK	Peptidoglycan-associated lipoprotein
F0316_14135	ENOG4108YGG	dna repair protein
F0316_14165	ENOG4105GVR	general secretion pathway protein D
F0316_14195	ENOG4105VZ1	Replication Protein
F0316_14210	ENOG4108ZJT	translation initiation factor, Sui1
F0316_14220	ENOG4105CPF	Cell wall formation (By similarity)
F0316_14230	ENOG4105CD5	CoA-binding domain protein
F0316_14235	ENOG4105CWB	LysR family transcriptional Regulator
F0316_14240	ENOG4105D05	Receptor
F0316_14255	ENOG4105KA0	thioesterase Superfamily protein
F0316_14280	ENOG4105CYM	Glutathione S-transferase
F0316_14295	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
F0316_14300	ENOG4108JQ5	ABC transporter
F0316_14305	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
F0316_14310	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
F0316_14315	ENOG4105E43	Extracellular solute-binding protein, family 5
F0316_14340	ENOG4105DUX	Transporter
F0316_14355	ENOG4107RCV	ABC transporter, permease
F0316_14370	ENOG4107STF	Involved in phosphonate degradation (By similarity)
F0316_14375	ENOG4108JPW	Aminotransferase
F0316_14380	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
F0316_14385	ENOG4105NXH	GreA GreB family elongation factor
F0316_14390	ENOG4105PAD	Hydrolase
F0316_14395	ENOG4105JQN	Transcriptional regulator
F0316_14405	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
F0316_14410	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
F0316_14415	ENOG4105CKU	formyltetrahydrofolate synthetase
F0316_14420	ENOG4105E0X	reductase
F0316_14425	ENOG4105EUJ	GTP cyclohydrolase i
F0316_14430	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
F0316_14435	ENOG4105D06	uba thif-type nad fad binding protein
F0316_14445	ENOG4105KHC	sulfurtransferase
F0316_14455	ENOG4107RHR	regulatoR
F0316_14465	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
F0316_14470	ENOG4105CV1	Transketolase (EC 2.2.1.1)
F0316_14490	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
F0316_14500	ENOG4108M3J	Dehydrogenase
F0316_14515	ENOG4105RA2	Membrane
F0316_14525	ENOG4105ETT	transcriptional Regulator, LysR family
F0316_14530	ENOG41067V3	Antibiotic biosynthesis monooxygenase
F0316_14535	ENOG4108RCM	Nitroreductase
F0316_14565	ENOG41080HT	Transcriptional regulator, arsr family
F0316_14575	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
F0316_14620	ENOG4105C5Y	PTS System
F0316_14625	ENOG4105ETE	Transcriptional regulator (LacI family
F0316_14630	ENOG4108HKT	sucrose-6-phosphate hydrolase
F0316_14635	ENOG4105D7K	pfkb domain protein
F0316_14640	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
F0316_14645	ENOG4108NVR	Methyl-accepting chemotaxis
F0316_14650	ENOG4105CDV	Ompa motb domain protein
F0316_14655	ENOG4108V1T	peptidylprolyl cis-trans isomerase
F0316_14660	ENOG4107VXZ	Hydrolase
F0316_14665	ENOG4108N3W	hemolysin secretion protein
F0316_14670	ENOG4105CEE	C4-dicarboxylate transporter
F0316_14675	ENOG4105EJQ	L-serine dehydratase
F0316_14695	ENOG4105ETE	Transcriptional regulator (LacI family
F0316_14700	ENOG4105WH1	Two component transcriptional regulator luxr family
F0316_14705	ENOG4105BZU	Histidine kinase
F0316_14720	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
F0316_14740	ENOG4105DHT	Metal Dependent Phosphohydrolase
F0316_14745	ENOG4108KX4	response regulator
F0316_14750	ENOG4105BZU	Histidine kinase
F0316_14755	ENOG4105CXY	transporter
F0316_14760	ENOG4105C4Y	ABC transporter
F0316_14765	ENOG4107RCV	ABC transporter, permease
F0316_14770	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
F0316_14775	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
F0316_14785	ENOG4105CHU	acetyl-coa acetyltransferase
F0316_14795	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
F0316_14800	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
F0316_14815	ENOG4105BZU	Histidine kinase
F0316_14820	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
F0316_14830	ENOG4108I6A	alcohol dehydrogenase
F0316_14840	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
F0316_14850	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
F0316_14855	ENOG4105CXY	transporter
F0316_14860	ENOG4105CA9	Pyruvate kinase
F0316_14865	ENOG4105BZU	Histidine kinase
F0316_14870	ENOG4108SV3	Tmao reductase system periplasmic protein tort
F0316_14875	ENOG4108Z5K	methylglyoxal synthase
F0316_14880	ENOG4108RWI	nicotinamidase
F0316_14885	ENOG41080IJ	Diacylglycerol kinase
F0316_14900	ENOG41088T4	Helicase IV
F0316_14905	ENOG4105EM2	membrane
F0316_14935	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
F0316_14940	ENOG4105E0C	molybdate abc transporter
F0316_14945	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
F0316_14950	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
F0316_14960	ENOG4105CC0	LysR family Transcriptional regulator
F0316_14990	ENOG4105BZU	Histidine kinase
F0316_14995	ENOG4108QGH	periplasmic
F0316_15005	ENOG41082IR	Excinuclease ABC C subunit domain protein
F0316_15035	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
F0316_15040	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
F0316_15045	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
F0316_15050	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
F0316_15055	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
F0316_15060	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
F0316_15065	ENOG4105K63	Thioredoxin
F0316_15095	ENOG4105DMR	ABC, transporter
F0316_15100	ENOG4105GBT	ABC transporter
F0316_15105	ENOG4106PMH	Extracellular solute-binding protein family 3
F0316_15110	ENOG4105E5Z	arginine transporter ATP-binding subunit
F0316_15120	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
F0316_15130	ENOG4108YZ4	nudix hydrolase
F0316_15135	ENOG4105C5W	Aldolase
F0316_15140	ENOG4106RE7	Cytochrome
F0316_15145	ENOG4108IG5	Transcriptional regulator
F0316_15150	ENOG4105C1J	atp-dependent rna helicase
F0316_15155	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
F0316_15165	ENOG4105E0U	tyrosine-specific transport protein
F0316_15170	ENOG4108N3W	hemolysin secretion protein
F0316_15175	ENOG4105CMR	udp-glucose 4-epimerase
F0316_15185	ENOG4105E7W	lamb ycsf family protein
F0316_15195	ENOG4107R7A	Allophanate hydrolase subunit 2
F0316_15205	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
F0316_15210	ENOG4105CV6	ABC transporter, permease
F0316_15215	ENOG4108I0Y	(ABC) transporter
F0316_15225	ENOG4105RKW	reductase (By
F0316_15245	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
F0316_15260	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
F0316_15275	ENOG4107RE1	Inosine-guanosine kinase
F0316_15280	ENOG4105E0M	Sulfatase
F0316_15290	ENOG4105C1J	atp-dependent rna helicase
F0316_15295	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
F0316_15305	ENOG4105CVA	phosphate
F0316_15315	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
F0316_15320	ENOG4108M1A	Chitin-binding protein
F0316_15325	ENOG4105D4Y	metalloprotease
F0316_15335	ENOG4105CYW	agmatinase
F0316_15340	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
F0316_15350	ENOG4105CJW	magnesium transporter
F0316_15355	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
F0316_15360	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
F0316_15370	ENOG4105CZK	Aspartate kinase
F0316_15375	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
F0316_15380	ENOG4108JPW	Aminotransferase
F0316_15385	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
F0316_15395	ENOG41090A4	Pterin carbinolamine dehydratase
F0316_15400	ENOG4105MIR	Phenylalanine 4-monooxygenase
F0316_15405	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
F0316_15425	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
F0316_15430	ENOG4105EGI	Transcriptional regulator
F0316_15445	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
F0316_15450	ENOG4105C37	(CBS) domain
F0316_15455	ENOG4108UKZ	OsmC family
F0316_15460	ENOG4107YWA	deoxycytidylate deaminase
F0316_15485	ENOG4105DVH	amino acid
F0316_15490	ENOG4106TD9	Diguanylate cyclase
F0316_15500	ENOG4108VAC	response regulator
F0316_15505	ENOG4108HRK	Histidine kinase
F0316_15520	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
F0316_15525	ENOG4105C19	ABC transporter
F0316_15540	ENOG4107RGM	aldo keto reductase
F0316_15545	ENOG4107T9C	Alpha amylase catalytic region
F0316_15555	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
F0316_15560	ENOG4108M0H	Extracellular lipase
F0316_15565	ENOG4107SDU	Methyl-accepting chemotaxis
F0316_15570	ENOG4105D4Y	metalloprotease
F0316_15580	ENOG4105EIF	outer membrane protein W
F0316_15590	ENOG41061WM	D-Alanyl-D-Alanine
F0316_15595	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
F0316_15600	ENOG4105VEQ	Cold shock protein
F0316_15610	ENOG4105BZC	d-serine deaminase
F0316_15615	ENOG4105W8I	Transcriptional regulator
F0316_15630	ENOG4105CPQ	Dehydrogenase
F0316_15650	ENOG4105HEI	LysR family (Transcriptional regulator
F0316_15660	ENOG4105CHR	reductase
F0316_15775	ENOG4105VCP	PTS System
F0316_15785	ENOG4105CK1	PTS System
F0316_15790	ENOG4105CS2	ec 3.2.1.21
F0316_15795	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F0316_15800	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
F0316_15805	ENOG4105KT5	UmuD protein
F0316_15830	ENOG4105CAR	Terminase, large subunit
F0316_15845	ENOG4108XTP	Transcriptional regulator
F0316_15860	ENOG4107R08	Integrase
F0316_15885	ENOG4105CPQ	Dehydrogenase
F0316_15890	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
F0316_15895	ENOG4108IQK	o-acetylhomoserine
F0316_15900	ENOG4105EXG	Transcriptional regulator
F0316_15905	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
F0316_15925	ENOG4107SSZ	Phosphatase
F0316_15930	ENOG4105DHT	Metal Dependent Phosphohydrolase
F0316_15935	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
F0316_15940	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
F0316_15945	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
F0316_15970	ENOG4105BZW	Glycerate kinase
F0316_15975	ENOG4108NVR	Methyl-accepting chemotaxis
F0316_15980	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
F0316_15985	ENOG41090JE	Utilization Protein
F0316_15990	ENOG4105D4P	Coproporphyrinogen iii oxidase
F0316_15995	ENOG4105WQ5	TonB family
F0316_16000	ENOG41090AP	transport protein
F0316_16005	ENOG4106GFD	transport protein
F0316_16010	ENOG4107R4I	Periplasmic binding protein
F0316_16015	ENOG4105EHG	Permease protein
F0316_16020	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
F0316_16050	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_16055	ENOG4105QVC	MOSC domain-containing protein
F0316_16055	ENOG4105QVC	MOSC domain-containing protein
F0316_16060	ENOG4105EKE	dihydroorotase
F0316_16070	ENOG4105KAF	membrAne
F0316_16080	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
F0316_16085	ENOG4105CKW	Inner membrane protein yedI
F0316_16090	ENOG4108ESY	Metal dependent phosphohydrolase
F0316_16095	ENOG4105VEQ	Cold shock protein
F0316_16125	ENOG4105BZU	Histidine kinase
F0316_16130	ENOG4105E98	transcriptional regulator DeoR family
F0316_16145	ENOG4105EG2	ABC transporter, permease
F0316_16150	ENOG4105D56	permease protein
F0316_16155	ENOG4107FKK	extracellular solute-binding protein family 1
F0316_16160	ENOG4108IJ9	(ABC) transporter
F0316_16165	ENOG4108HK0	-acetyltransferase
F0316_16180	ENOG4105K8R	UPF0145 protein
F0316_16185	ENOG41086KC	Transcriptional regulator
F0316_16190	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
F0316_16195	ENOG4107R88	Chemotaxis protein (CheV)
F0316_16200	ENOG4105K56	Transcriptional regulator
F0316_16205	ENOG4106TD9	Diguanylate cyclase
F0316_16220	ENOG4105BZU	Histidine kinase
F0316_16240	ENOG4105ETT	transcriptional Regulator, LysR family
F0316_16245	ENOG4108K0B	C-di-gmp phosphodiesterase
F0316_16255	ENOG4105EUB	pirin domain protein
F0316_16260	ENOG4105NBK	UPF0345 protein
F0316_16270	ENOG4105E5W	Transporter
F0316_16280	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_16285	ENOG4105DAN	ATP-dependent protease
F0316_16295	ENOG4108JQ5	ABC transporter
F0316_16300	ENOG4105E89	ABC transporter
F0316_16305	ENOG4107SDU	Methyl-accepting chemotaxis
F0316_16315	ENOG4105CC0	LysR family Transcriptional regulator
F0316_16320	ENOG4105DAA	L-lactate
F0316_16325	ENOG4105DMF	Dehydrogenase
F0316_16335	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
F0316_16345	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
F0316_16355	ENOG4105C1J	atp-dependent rna helicase
F0316_16360	ENOG4105ECQ	AraC Family Transcriptional Regulator
F0316_16365	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
F0316_16380	ENOG4105BZ1	(ABC) transporter
F0316_16390	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
F0316_16425	ENOG4105K56	Transcriptional regulator
F0316_16430	ENOG4108ZHJ	Organic hydroperoxide resistance protein
F0316_16440	ENOG4108SXK	Transporter Drug Metabolite Exporter family
F0316_16445	ENOG4105VW4	glutaredoxin 3
F0316_16450	ENOG4108P2H	Inner membrane protein YjiG
F0316_16455	ENOG41074DU	domain protein
F0316_16460	ENOG4105DN9	Na H antiporter
F0316_16465	ENOG4106YYS	transcriptional regulatory protein
F0316_16470	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
F0316_16475	ENOG4107QPK	)-transporter
F0316_16485	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
F0316_16490	ENOG4105D03	DNA-3-methyladenine glycosylase II
F0316_16495	ENOG4108VGI	doxx family
F0316_16520	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
F0316_16530	ENOG4107W52	maltose operon periplasmic protein
F0316_16535	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
F0316_16550	ENOG4108N3W	hemolysin secretion protein
F0316_16565	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_16575	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
F0316_16580	ENOG4105CDA	abc transporter atp-binding protein
F0316_16590	ENOG4106TNF	Periplasmic binding protein
F0316_16595	ENOG4105EZ7	amino acid ABC transporter
F0316_16600	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
F0316_16605	ENOG4105CTS	PTS system mannitol-specific
F0316_16610	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
F0316_16615	ENOG4105E61	Mannitol repressor protein
F0316_16645	ENOG4108KTG	Membrane protein, drug metabolite transporter
F0316_16660	ENOG4108W2Y	isochorismatase
F0316_16670	ENOG4108RYK	Nad-dependent epimerase dehydratase
F0316_16675	ENOG4105JQN	Transcriptional regulator
F0316_16680	ENOG41069D7	Methyl-accepting chemotaxis
F0316_16685	ENOG4105EMU	Dehydrogenase
F0316_16690	ENOG4105JQN	Transcriptional regulator
F0316_16710	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
F0316_16715	ENOG4105D5Q	Arginine ornithine antiporter
F0316_16720	ENOG4105CXN	decarboxylase
F0316_16730	ENOG4107RGH	Aldehyde dehydrogenase
F0316_16735	ENOG4105EW9	transcriptional regulator AsnC family
F0316_16740	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_16750	ENOG4105CK7	Sodium proline symporter
F0316_16760	ENOG4105C26	Dehydrogenase
F0316_16775	ENOG4105E6M	Sulphatase-modifying factor protein
F0316_16785	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
F0316_16790	ENOG4107QZV	Type I secretion membrane fusion protein
F0316_16805	ENOG4108JJA	ABC, transporter
F0316_16815	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
F0316_16825	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_16830	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
F0316_16835	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
F0316_16840	ENOG4105BZU	Histidine kinase
F0316_16845	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_16850	ENOG4108V3W	Chemotaxis protein, CheW
F0316_16855	ENOG4108V3W	Chemotaxis protein, CheW
F0316_16860	ENOG4105CBS	Chea signal transduction histidine kinase
F0316_16865	ENOG4108VYJ	response regulator receiver protein
F0316_16880	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
F0316_16885	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F0316_16890	ENOG4108JQ6	ABC transporter
F0316_16895	ENOG4105DIJ	Phosphoethanolamine transferase
F0316_16900	ENOG4105DHQ	Histidine kinase
F0316_16905	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
F0316_16915	ENOG4105EMU	Dehydrogenase
F0316_16935	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
F0316_16940	ENOG4107RUE	extracellular solute-binding protein family 1
F0316_16945	ENOG4106RMF	ParB family
F0316_16980	ENOG4105CDY	transcriptional regulatory protein
F0316_16985	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
F0316_16990	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_17000	ENOG4108YYI	Protein of unknown function (DUF2810)
F0316_17005	ENOG41061ZR	Transcriptional regulator
F0316_17010	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
F0316_17015	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
F0316_17020	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
F0316_17030	ENOG4108WC9	type VI secretion system effector, hcp1 family
F0316_17035	ENOG4105CS6	Rhs element vgr protein
F0316_17060	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
F0316_17070	ENOG4105C8P	)-transporter
F0316_17075	ENOG4108Q67	UPF0319 protein
F0316_17100	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_17120	ENOG4105EYK	Phosphatidylglycerophosphatase B
F0316_17130	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
F0316_17155	ENOG4105D6U	Sodium Glutamate Symporter
F0316_17160	ENOG4105YE1	PilZ domain
F0316_17175	ENOG4105EFX	secretion protein, HlyD family
F0316_17180	ENOG4105KK7	inner membrane protein YiaW
F0316_17185	ENOG4106TD9	Diguanylate cyclase
F0316_17200	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
F0316_17210	ENOG4107SEY	Conserved Protein
F0316_17220	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
F0316_17225	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
F0316_17235	ENOG4105C1J	atp-dependent rna helicase
F0316_17240	ENOG4105CUG	Oligopeptidase b
F0316_17245	ENOG4107ENK	receptor
F0316_17270	ENOG4105CVA	phosphate
F0316_17275	ENOG4105C8U	phosphate abc transporter
F0316_17280	ENOG4105E2Z	phosphate ABC transporter (Permease
F0316_17285	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
F0316_17290	ENOG4105BZU	Histidine kinase
F0316_17305	ENOG4105DWD	nucleoside recognition domain protein
F0316_17310	ENOG4105CHH	sulfate transporter
F0316_17325	ENOG4105DR5	peptidase
F0316_17330	ENOG4105BZU	Histidine kinase
F0316_17335	ENOG4105EQ2	LysR family Transcriptional regulator
F0316_17340	ENOG4105E5M	Multidrug resistance protein D
F0316_17345	ENOG4108Z4X	TRANSCRIPTIONal
F0316_17365	ENOG4105CK2	sodium dicarboxylate symporter
F0316_17420	ENOG4107RH7	Nicotinate phosphoribosyltransferase
F0316_17425	ENOG4105D9R	oxidoreductase
F0316_17435	ENOG4105BZU	Histidine kinase
F0316_17440	ENOG4107VXZ	Hydrolase
F0316_17450	ENOG4105D3G	Pseudouridine synthase
F0316_17510	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F0316_17515	ENOG4108JUB	Transcriptional regulator
F0316_17545	ENOG4105CS6	Rhs element vgr protein
F0316_17555	ENOG4108J1Q	
F0316_17565	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
F0316_17570	ENOG4105C2J	ABC transporter
F0316_17575	ENOG4105CNN	ABC, transporter
F0316_17580	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
F0316_17585	ENOG4108RVA	ribokinase
F0316_17590	ENOG4105ETE	Transcriptional regulator (LacI family
F0316_17595	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
F0316_17600	ENOG4108I5U	Uridine phosphorylase
F0316_17610	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
F0316_17615	ENOG4105CXY	transporter
F0316_17630	ENOG4105CQZ	Histidine kinase
F0316_17635	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F0316_17655	ENOG4105D5U	fad dependent oxidoreductase
F0316_17665	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
F0316_17680	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
F0316_17685	ENOG4105ETE	Transcriptional regulator (LacI family
F0316_17695	ENOG4105KJM	monovalent cation h antiporter subunit g
F0316_17700	ENOG41080TA	Multiple resistance and ph regulation protein f
F0316_17705	ENOG4105SC1	monovalent cation H antiporter subunit E
F0316_17710	ENOG4108JPZ	Monovalent cation H antiporter subunit D
F0316_17715	ENOG4105MKQ	Monovalent cation H antiporter subunit C
F0316_17720	ENOG4105D65	subunit l
F0316_17730	ENOG4105Q9Y	Universal stress protein
F0316_17735	ENOG4105CIC	tryptophan-specific transport protein
F0316_17740	ENOG4105C0F	tryptophanase EC 4.1.99.1
F0316_17750	ENOG4105VRT	cytoplasmic protein
F0316_17760	ENOG4105BZU	Histidine kinase
F0316_17765	ENOG4105VEQ	Cold shock protein
F0316_17780	ENOG4107QVM	von Willebrand factor, type A
F0316_17800	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
F0316_17805	ENOG41069D7	Methyl-accepting chemotaxis
F0316_17820	ENOG4105D9N	nucleoside
F0316_17825	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
F0316_17835	ENOG4108JUA	Transcriptional regulator
F0316_17840	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
F0316_17845	ENOG4105VEQ	Cold shock protein
F0316_17865	ENOG4108UNF	response regulator
F0316_17875	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
F0316_17880	ENOG4105C5I	Dehydrogenase
F0316_17905	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
F0316_17910	ENOG4105C1J	atp-dependent rna helicase
F0316_17915	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
F0316_17920	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
F0316_17925	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
F0316_17930	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
F0316_17935	ENOG4105BZU	Histidine kinase
F0316_17945	ENOG4107S6Z	Na H antiporter
F0316_17950	ENOG4105E5M	Multidrug resistance protein D
F0316_17960	ENOG4105BZU	Histidine kinase
F0316_17965	ENOG4105KUU	lipolytic protein G-D-S-L family
F0316_17970	ENOG4106M3D	hemolysin
F0316_17975	ENOG4108N3W	hemolysin secretion protein
F0316_17980	ENOG4107IFA	Lipase (EC 3.1.1.3)
F0316_17990	ENOG4107G87	m6 family metalloprotease domain protein
F0316_18010	ENOG4105DHS	permease protein
F0316_18015	ENOG4105CM4	permease protein
F0316_18020	ENOG4108IPW	abc transporter atp-binding protein
F0316_18040	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
F0316_18065	ENOG4105ETX	regulatoR
F0316_18075	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
F0316_18085	ENOG410667J	hydrolase
F0316_18140	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
F0316_18160	ENOG4108IJF	Heavy metal efflux pump, CzcA
F0316_18185	ENOG4105C8Q	Methyl-accepting chemotaxis
F0316_18195	ENOG4105DZ1	carboxypeptidase
F0316_18215	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F0316_18220	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
F0316_18225	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
F0316_18235	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
F0316_18240	ENOG4105C22	threonyL-tRNA synthetase
F0316_18245	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
F0316_18250	ENOG41082NX	50s ribosomal protein l35
F0316_18255	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
F0316_18380	ENOG4108J1Q	
F0316_18400	ENOG4108J1Q	
F0316_18625	ENOG4108J1Q	
F0316_18655	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
F0316_18730	ENOG4105EST	Metal Dependent Phosphohydrolase
F0316_18760	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
F0316_18800	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
F0316_18875	ENOG4105QNF	Outer membrane lipoprotein
F0316_18880	ENOG4105D9U	N-acetyltransferase
F0316_18915	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
F0316_18990	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
F0316_19095	ENOG41080ET	plasmid maintenance system killer protein
F0316_19100	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
F0316_19150	ENOG4108J1Q	
F0316_19315	ENOG4108S58	Phenazine biosynthesis protein PhzF
F0316_19395	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
F0316_19495	ENOG4108RS6	transposase
F0316_19555	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
F0316_19560	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
F0316_19565	ENOG4105CGF	Aromatic amino acid aminotransferase
F0316_19570	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
F0316_19575	ENOG4105DM4	PTS System
F0316_19580	ENOG4105DE4	1-phosphofructokinase
F0316_19585	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
F0316_19590	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
F0316_19595	ENOG4107RFY	SbcCD D subunit
F0316_19600	ENOG4105EYH	Exonuclease
F0316_19605	ENOG4108MGY	Histidine kinase
F0316_19615	ENOG4107KBT	8-Amino-7-oxononanoate synthase
F0316_19625	ENOG4105CMQ	Chloride channel
F0316_19630	ENOG4105CKI	cobalamin synthesis protein
F0316_19635	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
F0316_19640	ENOG4105DFH	Transport of potassium into the cell (By similarity)
F0316_19645	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
F0316_19650	ENOG4105C08	Histidine kinase
F0316_19655	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
F0316_19660	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
F0316_19665	ENOG4108RHM	integral membrane protein
F0316_19675	ENOG4105EPM	Diguanylate phosphodiesterase
F0316_19685	ENOG4105DS1	cytochrome b561
F0316_19695	ENOG4105TMB	Formate nitrite transporter
F0316_19700	ENOG4105DUM	transcriptional regulator, lysR family
F0316_19705	ENOG4108UQ5	membrane protein YcdZ
F0316_19710	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
F0316_19715	ENOG4105CGH	5'-nucleotidase
F0316_19720	ENOG4105DU1	integral membrane protein, terc
F0316_19730	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
F0316_19765	ENOG4105BZU	Histidine kinase
F0316_19775	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
F0316_19785	ENOG4105BZU	Histidine kinase
F0316_19800	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
F0316_19805	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)