locus-tag	class	description
VCSRO5_0001	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCSRO5_0002	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
VCSRO5_0003	COG0706	membrane insertase activity
VCSRO5_0004	COG0594	ribonuclease P activity
VCSRO5_0005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VCSRO5_0006	COG1126	abc transporter atp-binding protein
VCSRO5_0009	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VCSRO5_0010	COG0592	DNA-directed DNA polymerase activity
VCSRO5_0011	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VCSRO5_0012	COG0187	DNA topoisomerase II activity
VCSRO5_0015	COG0071	Belongs to the small heat shock protein (HSP20) family
VCSRO5_0016	COG3977	Valine--pyruvate aminotransferase
VCSRO5_0017	COG0751	glycine-tRNA ligase activity
VCSRO5_0018	COG0752	glycyl-tRNA synthetase alpha subunit
VCSRO5_0019	COG2119	membrane
VCSRO5_0021	COG0425	Belongs to the sulfur carrier protein TusA family
VCSRO5_0023	COG0604	alcohol dehydrogenase
VCSRO5_0025	COG0129	dihydroxy-acid dehydratase activity
VCSRO5_0026	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCSRO5_0029	COG0606	chelatase, subunit chli
VCSRO5_0030	COG0204	Acyl-transferase
VCSRO5_0031	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCSRO5_0032	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VCSRO5_0034	COG3084	Protein conserved in bacteria
VCSRO5_0035	COG4326	sporulation control protein
VCSRO5_0036	COG1272	protein, Hemolysin III
VCSRO5_0038	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCSRO5_0039	COG0569	domain protein
VCSRO5_0040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VCSRO5_0040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCSRO5_0041	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VCSRO5_0042	COG0242	peptide deformylase activity
VCSRO5_0043	COG1652	LysM domain
VCSRO5_0044	COG0758	DNA mediated transformation
VCSRO5_0045	COG2922	Belongs to the Smg family
VCSRO5_0046	COG0551	DNA topoisomerase type I activity
VCSRO5_0047	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VCSRO5_0048	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VCSRO5_0049	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO5_0050	COG0408	coproporphyrinogen oxidase activity
VCSRO5_0051	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VCSRO5_0053	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VCSRO5_0060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VCSRO5_0061	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VCSRO5_0063	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCSRO5_0064	COG2104	thiamine diphosphate biosynthetic process
VCSRO5_0065	COG2022	thiamine diphosphate biosynthetic process
VCSRO5_0066	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCSRO5_0067	COG0006	proline dipeptidase activity
VCSRO5_0071	COG1522	sequence-specific DNA binding
VCSRO5_0072	COG5001	Diguanylate cyclase
VCSRO5_0072	COG5002	protein histidine kinase activity
VCSRO5_0076	COG0589	response to stress
VCSRO5_0077	COG1528	Iron-storage protein
VCSRO5_0079	COG2081	HI0933 family
VCSRO5_0081	COG1322	Protein conserved in bacteria
VCSRO5_0082	COG2226	methyltransferase
VCSRO5_0085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO5_0086	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO5_0087	COG0805	protein transport
VCSRO5_0088	COG1858	cytochrome C peroxidase
VCSRO5_0089	COG0534	Mate efflux family protein
VCSRO5_0091	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VCSRO5_0092	COG2937	Belongs to the GPAT DAPAT family
VCSRO5_0093	COG3385	transposase activity
VCSRO5_0094	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VCSRO5_0095	COG3161	chorismate lyase activity
VCSRO5_0096	COG1580	Controls the rotational direction of flagella during chemotaxis
VCSRO5_0097	COG0840	transmembrane signaling receptor activity
VCSRO5_0099	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO5_0100	COG0084	hydrolase, TatD family'
VCSRO5_0103	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO5_0103	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO5_0107	COG3078	GTPase activator activity
VCSRO5_0110	COG3071	HemY protein
VCSRO5_0111	COG2959	enzyme of heme biosynthesis
VCSRO5_0112	COG1587	Uroporphyrinogen-III synthase
VCSRO5_0113	COG0181	hydroxymethylbilane synthase activity
VCSRO5_0115	COG1965	Belongs to the frataxin family
VCSRO5_0116	COG0019	diaminopimelate decarboxylase activity
VCSRO5_0117	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VCSRO5_0119	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VCSRO5_0120	COG1011	Hydrolase
VCSRO5_0121	COG3287	FIST C domain
VCSRO5_0121	COG2200	EAL domain
VCSRO5_0121	COG2199	diguanylate cyclase activity
VCSRO5_0122	COG3148	PFAM DTW domain containing protein
VCSRO5_0124	COG0561	phosphatase activity
VCSRO5_0125	COG2267	carboxylic ester hydrolase activity
VCSRO5_0126	COG1280	lysine exporter protein (LysE YggA)
VCSRO5_0127	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCSRO5_0128	COG0783	Belongs to the Dps family
VCSRO5_0133	COG0742	ribosomal rna small subunit methyltransferase
VCSRO5_0134	COG0552	protein localization to endoplasmic reticulum
VCSRO5_0135	COG2884	Cell division ATP-binding protein ftsE
VCSRO5_0136	COG2177	Part of the ABC transporter FtsEX involved in
VCSRO5_0137	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCSRO5_0138	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO5_0141	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCSRO5_0143	COG1404	Belongs to the peptidase S8 family
VCSRO5_0144	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
VCSRO5_0157	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VCSRO5_0158	COG3300	MHYT domain
VCSRO5_0158	COG5001	Diguanylate cyclase
VCSRO5_0160	COG3852	Histidine kinase
VCSRO5_0162	COG0174	glutamine synthetase
VCSRO5_0164	COG1217	gtp-binding protein TYPA
VCSRO5_0166	COG1295	ribonuclease BN
VCSRO5_0167	COG1490	D-aminoacyl-tRNA deacylase activity
VCSRO5_0168	COG0456	acetyltransferase
VCSRO5_0170	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
VCSRO5_0171	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VCSRO5_0172	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VCSRO5_0173	COG3031	protein transport across the cell outer membrane
VCSRO5_0175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO5_0176	COG1459	type II secretion system
VCSRO5_0177	COG2165	general secretion pathway protein
VCSRO5_0178	COG2165	general secretion pathway protein
VCSRO5_0179	COG2165	general secretion pathway protein
VCSRO5_0180	COG4795	General secretion pathway protein
VCSRO5_0181	COG3156	type II secretion system protein K
VCSRO5_0182	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCSRO5_0183	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCSRO5_0185	COG1218	3'(2'),5'-bisphosphate nucleotidase
VCSRO5_0186	COG0494	nUDIX hydrolase
VCSRO5_0188	COG1040	competence protein
VCSRO5_0189	COG0596	Alpha beta hydrolase
VCSRO5_0191	COG2183	response to ionizing radiation
VCSRO5_0192	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO5_0193	COG2199	diguanylate cyclase activity
VCSRO5_0196	COG2233	PERMEase
VCSRO5_0197	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VCSRO5_0198	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCSRO5_0199	COG1758	RNA polymerase activity
VCSRO5_0200	COG0194	GDP metabolic process
VCSRO5_0201	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VCSRO5_0202	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCSRO5_0206	COG4232	protein-disulfide reductase activity
VCSRO5_0208	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCSRO5_0209	COG3385	transposase activity
VCSRO5_0210	COG1027	Aspartate ammonia-lyase
VCSRO5_0211	COG3706	GGDEF domain
VCSRO5_0212	COG3030	protein affecting phage T7 exclusion by the F plasmid
VCSRO5_0213	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VCSRO5_0215	COG2205	protein histidine kinase activity
VCSRO5_0216	COG0745	RESPONSE REGULATOR receiver
VCSRO5_0218	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VCSRO5_0219	COG0205	6-phosphofructokinase activity
VCSRO5_0220	COG1494	fructose-1,6-bisphosphatase
VCSRO5_0221	COG3074	FtsZ-dependent cytokinesis
VCSRO5_0222	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VCSRO5_0223	COG0460	homoserine dehydrogenase
VCSRO5_0223	COG0527	aspartate kinase activity
VCSRO5_0224	COG0626	cystathionine gamma-synthase activity
VCSRO5_0225	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
VCSRO5_0226	COG0281	malic enzyme
VCSRO5_0227	COG0281	malic enzyme
VCSRO5_0228	COG0254	rRNA binding
VCSRO5_0229	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VCSRO5_0230	COG1609	Transcriptional regulator
VCSRO5_0231	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCSRO5_0232	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VCSRO5_0233	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VCSRO5_0234	COG1575	Belongs to the MenA family. Type 1 subfamily
VCSRO5_0235	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCSRO5_0236	COG0534	Mate efflux family protein
VCSRO5_0237	COG0149	triose-phosphate isomerase activity
VCSRO5_0242	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCSRO5_0243	COG0459	protein refolding
VCSRO5_0245	COG1509	lysine 2,3-aminomutase activity
VCSRO5_0246	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCSRO5_0248	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VCSRO5_0249	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VCSRO5_0250	COG1053	succinate dehydrogenase
VCSRO5_0251	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VCSRO5_0252	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO5_0253	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VCSRO5_0254	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VCSRO5_0255	COG1045	serine acetyltransferase
VCSRO5_0257	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VCSRO5_0258	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VCSRO5_0259	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VCSRO5_0260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCSRO5_0261	COG0137	argininosuccinate synthase activity
VCSRO5_0262	COG0165	Argininosuccinate lyase
VCSRO5_0264	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO5_0265	COG0678	peroxiredoxin activity
VCSRO5_0265	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCSRO5_0267	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VCSRO5_0273	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VCSRO5_0274	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VCSRO5_0276	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VCSRO5_0277	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VCSRO5_0278	COG0546	phosphoglycolate phosphatase activity
VCSRO5_0279	COG0180	Tryptophanyl-tRNA synthetase
VCSRO5_0282	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCSRO5_0284	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VCSRO5_0289	COG3954	Phosphoribulokinase
VCSRO5_0291	COG0429	hydrolase of the alpha beta-hydrolase fold
VCSRO5_0293	COG0488	(ABC) transporter
VCSRO5_0294	COG2249	NAD(P)H dehydrogenase (quinone) activity
VCSRO5_0297	COG1047	Peptidyl-prolyl cis-trans
VCSRO5_0299	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VCSRO5_0300	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VCSRO5_0301	COG3083	sulfuric ester hydrolase activity
VCSRO5_0302	COG0557	exoribonuclease II activity
VCSRO5_0303	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCSRO5_0304	COG0051	transcription antitermination factor activity, RNA binding
VCSRO5_0305	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VCSRO5_0306	COG0088	Forms part of the polypeptide exit tunnel
VCSRO5_0307	COG0089	rRNA binding
VCSRO5_0308	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VCSRO5_0309	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VCSRO5_0310	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VCSRO5_0311	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VCSRO5_0312	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VCSRO5_0313	COG0255	Belongs to the universal ribosomal protein uL29 family
VCSRO5_0314	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VCSRO5_0315	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VCSRO5_0316	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VCSRO5_0317	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VCSRO5_0318	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VCSRO5_0319	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VCSRO5_0320	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
VCSRO5_0321	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VCSRO5_0322	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VCSRO5_0323	COG1841	ribosomal large subunit assembly
VCSRO5_0325	COG0201	protein transport
VCSRO5_0326	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCSRO5_0327	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VCSRO5_0328	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VCSRO5_0329	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VCSRO5_0330	COG0202	RNA polymerase activity
VCSRO5_0331	COG0203	ribosomal protein L17
VCSRO5_0333	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO5_0334	COG3266	domain, Protein
VCSRO5_0334	COG3061	Opacity-associated protein A
VCSRO5_0335	COG0697	spore germination
VCSRO5_0336	COG2153	protein acetylation
VCSRO5_0337	COG0513	Belongs to the DEAD box helicase family
VCSRO5_0339	COG0737	Belongs to the 5'-nucleotidase family
VCSRO5_0340	COG1648	precorrin-2 dehydrogenase activity
VCSRO5_0340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VCSRO5_0341	COG0175	sulfate reduction
VCSRO5_0342	COG2895	sulfate adenylyltransferase (ATP) activity
VCSRO5_0343	COG0529	Catalyzes the synthesis of activated sulfate
VCSRO5_0347	COG1136	(ABC) transporter
VCSRO5_0347	COG0577	efflux transmembrane transporter activity
VCSRO5_0350	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VCSRO5_0351	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO5_0352	COG0729	surface antigen
VCSRO5_0354	COG2105	PFAM AIG2 family protein
VCSRO5_0355	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VCSRO5_0357	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCSRO5_0358	COG0163	prenyltransferase activity
VCSRO5_0360	COG1178	ABC-type Fe3 transport system permease component
VCSRO5_0361	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VCSRO5_0362	COG3028	Belongs to the UPF0307 family
VCSRO5_0363	COG0312	modulator of DNA gyrase
VCSRO5_0364	COG2239	Acts as a magnesium transporter
VCSRO5_0365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO5_0366	COG1660	Displays ATPase and GTPase activities
VCSRO5_0367	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO5_0368	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCSRO5_0370	COG1137	ATPase activity
VCSRO5_0371	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VCSRO5_0374	COG0517	IMP dehydrogenase activity
VCSRO5_0374	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VCSRO5_0376	COG1127	ABC transporter
VCSRO5_0377	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VCSRO5_0378	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCSRO5_0379	COG2854	intermembrane phospholipid transfer
VCSRO5_0381	COG5007	Belongs to the BolA IbaG family
VCSRO5_0382	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VCSRO5_0384	COG0251	oxidation-reduction process
VCSRO5_0386	COG0540	Belongs to the ATCase OTCase family
VCSRO5_0388	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VCSRO5_0390	COG0564	pseudouridine synthase activity
VCSRO5_0391	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCSRO5_0392	COG0525	valine-tRNA ligase activity
VCSRO5_0393	COG2927	DNA polymerase III (CHI subunit)
VCSRO5_0394	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCSRO5_0395	COG0795	lipopolysaccharide-transporting ATPase activity
VCSRO5_0396	COG0795	lipopolysaccharide-transporting ATPase activity
VCSRO5_0399	COG3437	response regulator, receiver
VCSRO5_0408	COG0066	3-isopropylmalate dehydratase activity
VCSRO5_0409	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
VCSRO5_0410	COG0473	3-isopropylmalate dehydrogenase activity
VCSRO5_0415	COG0583	DNA-binding transcription factor activity
VCSRO5_0416	COG1022	Amp-dependent synthetase and ligase
VCSRO5_0417	COG0028	Belongs to the TPP enzyme family
VCSRO5_0418	COG0440	acetolactate synthase activity
VCSRO5_0419	COG3385	transposase activity
VCSRO5_0420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO5_0421	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VCSRO5_0422	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VCSRO5_0423	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VCSRO5_0424	COG3079	Belongs to the UPF0149 family
VCSRO5_0425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO5_0426	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO5_0429	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VCSRO5_0431	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VCSRO5_0432	COG1595	DNA-templated transcription, initiation
VCSRO5_0435	COG3086	response to oxidative stress
VCSRO5_0436	COG0481	GTPase activity
VCSRO5_0438	COG0571	ribonuclease III activity
VCSRO5_0439	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VCSRO5_0440	COG1381	Involved in DNA repair and RecF pathway recombination
VCSRO5_0441	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VCSRO5_0442	COG0736	holo-[acyl-carrier-protein] synthase activity
VCSRO5_0448	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCSRO5_0449	COG3956	TIGRFAM MazG family protein
VCSRO5_0450	COG0504	CTP synthase activity
VCSRO5_0451	COG0148	phosphopyruvate hydratase activity
VCSRO5_0453	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO5_0453	COG3267	Type II secretory pathway component ExeA
VCSRO5_0455	COG4991	sh3 domain protein
VCSRO5_0456	COG0306	phosphate transporter
VCSRO5_0457	COG1392	Phosphate transport regulator
VCSRO5_0458	COG3025	triphosphatase activity
VCSRO5_0460	COG0840	transmembrane signaling receptor activity
VCSRO5_0461	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VCSRO5_0462	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
VCSRO5_0462	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
VCSRO5_0463	COG1538	Outer membrane efflux protein
VCSRO5_0464	COG0494	nUDIX hydrolase
VCSRO5_0465	COG3151	Protein conserved in bacteria
VCSRO5_0467	COG3150	esterase
VCSRO5_0468	COG0187	DNA topoisomerase II activity
VCSRO5_0469	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VCSRO5_0471	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VCSRO5_0472	COG0237	dephospho-CoA kinase activity
VCSRO5_0474	COG1459	type II secretion system
VCSRO5_0475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO5_0479	COG0716	FMN binding
VCSRO5_0480	COG4974	Belongs to the 'phage' integrase family
VCSRO5_0481	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCSRO5_0482	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VCSRO5_0483	COG2186	Transcriptional regulator
VCSRO5_0484	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VCSRO5_0485	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCSRO5_0486	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO5_0488	COG3116	cell division
VCSRO5_0489	COG0768	penicillin binding
VCSRO5_0490	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VCSRO5_0491	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VCSRO5_0493	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VCSRO5_0494	COG0772	Belongs to the SEDS family
VCSRO5_0495	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
VCSRO5_0496	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCSRO5_0497	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VCSRO5_0498	COG0849	cell division
VCSRO5_0499	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VCSRO5_0500	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VCSRO5_0502	COG0653	protein targeting
VCSRO5_0503	COG0494	nUDIX hydrolase
VCSRO5_0504	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
VCSRO5_0505	COG0505	Belongs to the CarA family
VCSRO5_0506	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VCSRO5_0512	COG0730	response to heat
VCSRO5_0513	COG0583	DNA-binding transcription factor activity
VCSRO5_0514	COG2860	membrane
VCSRO5_0515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VCSRO5_0517	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VCSRO5_0519	COG0493	'glutamate synthase
VCSRO5_0520	COG0067	glutamate synthase
VCSRO5_0520	COG0069	glutamate synthase activity
VCSRO5_0520	COG0070	glutamate synthase
VCSRO5_0522	COG0067	glutamate synthase
VCSRO5_0522	COG0069	glutamate synthase activity
VCSRO5_0522	COG0070	glutamate synthase
VCSRO5_0523	COG1242	4 iron, 4 sulfur cluster binding
VCSRO5_0524	COG4251	negative regulation of phosphorylation
VCSRO5_0524	COG5001	Diguanylate cyclase
VCSRO5_0524	COG2203	Gaf domain
VCSRO5_0524	COG3706	GGDEF domain
VCSRO5_0525	COG0784	Response regulator, receiver
VCSRO5_0525	COG2198	Histidine kinase
VCSRO5_0525	COG5002	protein histidine kinase activity
VCSRO5_0526	COG0745	RESPONSE REGULATOR receiver
VCSRO5_0527	COG0745	RESPONSE REGULATOR receiver
VCSRO5_0529	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCSRO5_0532	COG0083	homoserine kinase activity
VCSRO5_0533	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VCSRO5_0534	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VCSRO5_0535	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VCSRO5_0536	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VCSRO5_0539	COG1115	amino acid carrier protein
VCSRO5_0540	COG3022	response to hydroperoxide
VCSRO5_0542	COG0084	hydrolase, TatD family'
VCSRO5_0543	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO5_0544	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VCSRO5_0545	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO5_0546	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VCSRO5_0547	COG0813	purine-nucleoside phosphorylase activity
VCSRO5_0549	COG0560	Phosphoserine phosphatase
VCSRO5_0550	COG3385	transposase activity
VCSRO5_0552	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VCSRO5_0553	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCSRO5_0554	COG1022	Amp-dependent synthetase and ligase
VCSRO5_0557	COG3250	beta-galactosidase activity
VCSRO5_0558	COG1609	Transcriptional regulator
VCSRO5_0559	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO5_0562	COG0189	ligase activity
VCSRO5_0562	COG0569	domain protein
VCSRO5_0564	COG0456	acetyltransferase
VCSRO5_0566	COG2171	N-acyltransferase activity
VCSRO5_0567	COG3141	response to X-ray
VCSRO5_0570	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VCSRO5_0571	COG1074	ATP-dependent DNA helicase activity
VCSRO5_0572	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VCSRO5_0574	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VCSRO5_0574	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCSRO5_0576	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VCSRO5_0577	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VCSRO5_0578	COG2166	iron-sulfur cluster assembly
VCSRO5_0579	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCSRO5_0580	COG0693	protein deglycase activity
VCSRO5_0581	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VCSRO5_0582	COG3248	Nucleoside-binding outer membrane protein
VCSRO5_0584	COG1595	DNA-templated transcription, initiation
VCSRO5_0586	COG2211	Major facilitator Superfamily
VCSRO5_0587	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCSRO5_0589	COG2813	Specifically methylates the guanine in position
VCSRO5_0590	COG0271	Belongs to the BolA IbaG family
VCSRO5_0591	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO5_0592	COG1805	sodium ion transport
VCSRO5_0593	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO5_0594	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO5_0595	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO5_0596	COG2871	sodium ion transport
VCSRO5_0597	COG1477	protein flavinylation
VCSRO5_0601	COG3706	GGDEF domain
VCSRO5_0602	COG0733	neurotransmitter:sodium symporter activity
VCSRO5_0604	COG0189	ligase activity
VCSRO5_0605	COG0189	ligase activity
VCSRO5_0605	COG4067	protein conserved in archaea
VCSRO5_0606	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO5_0607	COG2252	PERMEase
VCSRO5_0608	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VCSRO5_0609	COG1073	alpha beta
VCSRO5_0611	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VCSRO5_0612	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VCSRO5_0613	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VCSRO5_0614	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO5_0614	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO5_0617	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VCSRO5_0618	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCSRO5_0619	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VCSRO5_0620	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VCSRO5_0622	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VCSRO5_0623	COG0024	Methionine aminopeptidase
VCSRO5_0624	COG0052	Belongs to the universal ribosomal protein uS2 family
VCSRO5_0625	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VCSRO5_0626	COG0528	UMP kinase activity
VCSRO5_0627	COG0233	cytoplasmic translational termination
VCSRO5_0628	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VCSRO5_0629	COG0575	Belongs to the CDS family
VCSRO5_0630	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VCSRO5_0631	COG0750	zinc metalloprotease
VCSRO5_0633	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VCSRO5_0634	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO5_0635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCSRO5_0636	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO5_0637	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO5_0638	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
VCSRO5_0639	COG0587	DNA-directed DNA polymerase activity
VCSRO5_0640	COG0825	malonyl-CoA metabolic process
VCSRO5_0641	COG0037	tRNA processing
VCSRO5_0643	COG3479	Phenolic acid decarboxylase
VCSRO5_0644	COG0347	Belongs to the P(II) protein family
VCSRO5_0645	COG3021	interspecies interaction between organisms
VCSRO5_0646	COG1388	LysM domain
VCSRO5_0646	COG0741	lytic transglycosylase activity
VCSRO5_0647	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCSRO5_0648	COG2226	methyltransferase
VCSRO5_0649	COG0328	RNA-DNA hybrid ribonuclease activity
VCSRO5_0652	COG1960	acyl-CoA dehydrogenase activity
VCSRO5_0653	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCSRO5_0654	COG0121	glutamine amidotransferase
VCSRO5_0655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VCSRO5_0656	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VCSRO5_0657	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VCSRO5_0659	COG1187	pseudouridine synthase activity
VCSRO5_0660	COG2840	Smr protein MutS2
VCSRO5_0666	COG2608	mercury ion transmembrane transporter activity
VCSRO5_0666	COG2217	Heavy metal translocating P-type atpase
VCSRO5_0667	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCSRO5_0670	COG1629	transport
VCSRO5_0670	COG4774	siderophore transport
VCSRO5_0671	COG2375	cellular response to nickel ion
VCSRO5_0672	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCSRO5_0672	COG2226	methyltransferase
VCSRO5_0672	COG3433	isochorismatase activity
VCSRO5_0679	COG0784	Response regulator, receiver
VCSRO5_0679	COG0835	chemotaxis
VCSRO5_0680	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCSRO5_0681	COG1815	bacterial-type flagellum-dependent cell motility
VCSRO5_0684	COG1749	Flagellar hook protein flgE
VCSRO5_0685	COG4787	bacterial-type flagellum-dependent cell motility
VCSRO5_0687	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VCSRO5_0688	COG1706	bacterial-type flagellum-dependent cell motility
VCSRO5_0689	COG1705	Flagellar rod assembly protein muramidase FlgJ
VCSRO5_0689	COG3951	Flagellar rod assembly protein muramidase FlgJ
VCSRO5_0692	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO5_0693	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO5_0710	COG0012	GTP binding
VCSRO5_0711	COG0193	aminoacyl-tRNA hydrolase activity
VCSRO5_0712	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VCSRO5_0713	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VCSRO5_0714	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VCSRO5_0715	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VCSRO5_0716	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VCSRO5_0717	COG2890	protein-(glutamine-N5) methyltransferase activity
VCSRO5_0719	COG2912	Transglutaminase-like superfamily
VCSRO5_0720	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VCSRO5_0721	COG0737	Belongs to the 5'-nucleotidase family
VCSRO5_0722	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VCSRO5_0723	COG2233	PERMEase
VCSRO5_0727	COG1393	Belongs to the ArsC family
VCSRO5_0728	COG4783	chaperone-mediated protein folding
VCSRO5_0732	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VCSRO5_0735	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VCSRO5_0737	COG1876	peptidase activity
VCSRO5_0739	COG1393	Belongs to the ArsC family
VCSRO5_0743	COG2837	iron assimilation
VCSRO5_0744	COG3385	transposase activity
VCSRO5_0745	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO5_0746	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO5_0747	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO5_0748	COG1334	flagellar protein FlaG
VCSRO5_0749	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VCSRO5_0751	COG1516	flagellar protein fliS
VCSRO5_0755	COG1677	Flagellar hook-basal body complex protein FliE
VCSRO5_0757	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VCSRO5_0758	COG1317	bacterial-type flagellum organization
VCSRO5_0762	COG1580	Controls the rotational direction of flagella during chemotaxis
VCSRO5_0767	COG1987	bacterial-type flagellum assembly
VCSRO5_0768	COG1684	flagellar biosynthetic protein fliR
VCSRO5_0770	COG2840	Smr protein MutS2
VCSRO5_0771	COG2890	protein-(glutamine-N5) methyltransferase activity
VCSRO5_0772	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VCSRO5_0773	COG2860	membrane
VCSRO5_0774	COG3101	peptidyl-lysine hydroxylation
VCSRO5_0776	COG0431	NADPH-dependent FMN reductase
VCSRO5_0777	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VCSRO5_0777	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VCSRO5_0778	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCSRO5_0779	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO5_0780	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCSRO5_0781	COG0735	belongs to the Fur family
VCSRO5_0783	COG0583	DNA-binding transcription factor activity
VCSRO5_0788	COG0596	Alpha beta hydrolase
VCSRO5_0789	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VCSRO5_0790	COG0033	Phosphoglucomutase
VCSRO5_0792	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VCSRO5_0793	COG0372	Belongs to the citrate synthase family
VCSRO5_0794	COG2009	succinate dehydrogenase
VCSRO5_0795	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VCSRO5_0796	COG1053	succinate dehydrogenase
VCSRO5_0798	COG0567	Dehydrogenase, E1 component
VCSRO5_0799	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCSRO5_0800	COG0045	succinate-CoA ligase (ADP-forming) activity
VCSRO5_0802	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VCSRO5_0803	COG1121	(ABC) transporter
VCSRO5_0804	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VCSRO5_0805	COG4977	sequence-specific DNA binding
VCSRO5_0806	COG1918	ferrous iron import across plasma membrane
VCSRO5_0810	COG0018	arginyl-trna synthetase
VCSRO5_0813	COG1025	Belongs to the peptidase M16 family
VCSRO5_0814	COG2062	phosphohistidine phosphatase, SixA
VCSRO5_0820	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VCSRO5_0821	COG0784	Response regulator, receiver
VCSRO5_0821	COG2198	Histidine kinase
VCSRO5_0821	COG0643	Histidine kinase
VCSRO5_0822	COG2201	protein-glutamate methylesterase activity
VCSRO5_0823	COG1192	Involved in chromosome partitioning
VCSRO5_0825	COG0835	chemotaxis
VCSRO5_0827	COG4133	protoheme IX ABC transporter activity
VCSRO5_0828	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCSRO5_0829	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCSRO5_0831	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VCSRO5_0832	COG1138	Cytochrome C-type biogenesis protein
VCSRO5_0833	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VCSRO5_0836	COG2853	Lipoprotein
VCSRO5_0840	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VCSRO5_0841	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCSRO5_0842	COG0123	including yeast histone deacetylase and acetoin utilization protein
VCSRO5_0845	COG3083	sulfuric ester hydrolase activity
VCSRO5_0846	COG3082	Protein of unknown function (DUF1414)
VCSRO5_0847	COG3081	Nucleoid-associated protein
VCSRO5_0849	COG1757	Na H antiporter
VCSRO5_0850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCSRO5_0851	COG2095	MarC family integral membrane protein
VCSRO5_0852	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO5_0852	COG1454	alcohol dehydrogenase
VCSRO5_0854	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO5_0855	COG1530	ribonuclease E activity
VCSRO5_0856	COG0564	pseudouridine synthase activity
VCSRO5_0857	COG0424	maF-like protein
VCSRO5_0858	COG1399	metal-binding, possibly nucleic acid-binding protein
VCSRO5_0859	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VCSRO5_0860	COG0416	fatty acid biosynthetic process
VCSRO5_0861	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCSRO5_0863	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO5_0864	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VCSRO5_0865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCSRO5_0866	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCSRO5_0867	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VCSRO5_0868	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VCSRO5_0870	COG0084	hydrolase, TatD family'
VCSRO5_0871	COG1263	PTS System
VCSRO5_0871	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO5_0873	COG0733	neurotransmitter:sodium symporter activity
VCSRO5_0876	COG4667	esterase of the alpha-beta hydrolase superfamily
VCSRO5_0878	COG1940	carbohydrate kinase activity
VCSRO5_0879	COG0784	Response regulator, receiver
VCSRO5_0879	COG0835	chemotaxis
VCSRO5_0882	COG2226	methyltransferase
VCSRO5_0884	COG0676	glucose-6-phosphate 1-epimerase activity
VCSRO5_0885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO5_0886	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO5_0888	COG3139	Protein of unknown function (DUF1315)
VCSRO5_0889	COG0252	asparaginase activity
VCSRO5_0890	COG0616	signal peptide processing
VCSRO5_0891	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCSRO5_0891	COG1902	pentaerythritol trinitrate reductase activity
VCSRO5_0892	COG0788	formyltetrahydrofolate deformylase activity
VCSRO5_0894	COG1199	ATP-dependent helicase activity
VCSRO5_0895	COG1214	PFAM Peptidase M22, glycoprotease
VCSRO5_0898	COG0596	Alpha beta hydrolase
VCSRO5_0899	COG0318	PFAM AMP-dependent synthetase and ligase
VCSRO5_0900	COG0318	PFAM AMP-dependent synthetase and ligase
VCSRO5_0901	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VCSRO5_0904	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VCSRO5_0905	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VCSRO5_0906	COG0436	Aminotransferase
VCSRO5_0907	COG1169	isochorismate synthase
VCSRO5_0908	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VCSRO5_0909	COG0596	Alpha beta hydrolase
VCSRO5_0913	COG3135	benzoate transporter
VCSRO5_0919	COG3015	lipoprotein NlpE involved in copper resistance
VCSRO5_0920	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VCSRO5_0921	COG2894	cell division
VCSRO5_0922	COG0850	regulation of cytokinetic process
VCSRO5_0923	COG3100	YcgL domain-containing protein
VCSRO5_0924	COG2951	lytic endotransglycosylase activity
VCSRO5_0926	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO5_0929	COG3005	denitrification pathway
VCSRO5_0930	COG0243	molybdopterin cofactor binding
VCSRO5_0934	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO5_0936	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VCSRO5_0944	COG4589	Belongs to the CDS family
VCSRO5_0946	COG5001	Diguanylate cyclase
VCSRO5_0946	COG3300	MHYT domain
VCSRO5_0949	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VCSRO5_0950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCSRO5_0951	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCSRO5_0952	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCSRO5_0954	COG4191	Histidine kinase
VCSRO5_0955	COG0544	peptidyl-prolyl cis-trans isomerase activity
VCSRO5_0957	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VCSRO5_0958	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VCSRO5_0959	COG0776	regulation of translation
VCSRO5_0960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO5_0961	COG1555	photosystem II stabilization
VCSRO5_0962	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VCSRO5_0963	COG0539	negative regulation of cytoplasmic translation
VCSRO5_0964	COG0776	regulation of translation
VCSRO5_0965	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VCSRO5_0966	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VCSRO5_0970	COG0583	DNA-binding transcription factor activity
VCSRO5_0972	COG0686	Belongs to the AlaDH PNT family
VCSRO5_0974	COG1674	ftsk spoiiie
VCSRO5_0975	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VCSRO5_0976	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCSRO5_0977	COG2186	Transcriptional regulator
VCSRO5_0980	COG0537	adenosine 5'-monophosphoramidase activity
VCSRO5_0985	COG3150	esterase
VCSRO5_0986	COG1252	NADH dehydrogenase
VCSRO5_0990	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VCSRO5_0992	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO5_0993	COG1136	(ABC) transporter
VCSRO5_0994	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO5_0996	COG0658	competence protein
VCSRO5_0996	COG2333	competence protein COMEC
VCSRO5_0997	COG1132	(ABC) transporter
VCSRO5_0998	COG1663	tetraacyldisaccharide 4'-kinase activity
VCSRO5_0999	COG2835	tetraacyldisaccharide 4'-kinase activity
VCSRO5_1000	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VCSRO5_1001	COG2719	SpoVR family
VCSRO5_1002	COG2718	Belongs to the UPF0229 family
VCSRO5_1003	COG2766	serine protein kinase
VCSRO5_1004	COG3013	Belongs to the UPF0304 family
VCSRO5_1006	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VCSRO5_1007	COG0840	transmembrane signaling receptor activity
VCSRO5_1009	COG1882	Formate acetyltransferase
VCSRO5_1015	COG4160	amino acid transport
VCSRO5_1016	COG0708	Exodeoxyribonuclease III
VCSRO5_1017	COG0840	transmembrane signaling receptor activity
VCSRO5_1019	COG3923	Primosomal replication protein n
VCSRO5_1020	COG0730	response to heat
VCSRO5_1021	COG1199	ATP-dependent helicase activity
VCSRO5_1022	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCSRO5_1023	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCSRO5_1024	COG3012	SEC-C Motif Domain Protein
VCSRO5_1025	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCSRO5_1026	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO5_1027	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCSRO5_1028	COG0215	cysteine-tRNA ligase activity
VCSRO5_1029	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VCSRO5_1030	COG0632	four-way junction helicase activity
VCSRO5_1033	COG1271	oxidase subunit
VCSRO5_1034	COG1294	oxidase, subunit
VCSRO5_1035	COG4890	Cyd operon protein YbgT
VCSRO5_1036	COG3790	cyd operon protein YbgE
VCSRO5_1037	COG0824	Thioesterase
VCSRO5_1038	COG0811	peptide transport
VCSRO5_1041	COG0823	Involved in the tonB-independent uptake of proteins
VCSRO5_1042	COG2885	chlorophyll binding
VCSRO5_1044	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VCSRO5_1046	COG0784	Response regulator, receiver
VCSRO5_1046	COG5002	protein histidine kinase activity
VCSRO5_1048	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO5_1049	COG3284	Transcriptional regulator
VCSRO5_1050	COG4628	conserved protein (DUF2132)
VCSRO5_1052	COG0415	Belongs to the DNA photolyase family
VCSRO5_1054	COG5001	Diguanylate cyclase
VCSRO5_1057	COG1401	restriction endodeoxyribonuclease activity
VCSRO5_1064	COG4409	exo-alpha-(2->6)-sialidase activity
VCSRO5_1065	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VCSRO5_1066	COG1940	carbohydrate kinase activity
VCSRO5_1068	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCSRO5_1069	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCSRO5_1070	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCSRO5_1071	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VCSRO5_1072	COG1737	Transcriptional regulator
VCSRO5_1073	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VCSRO5_1074	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VCSRO5_1076	COG4932	domain protein
VCSRO5_1076	COG5492	domain, Protein
VCSRO5_1081	COG2267	carboxylic ester hydrolase activity
VCSRO5_1083	COG3064	Membrane
VCSRO5_1104	COG4789	Type iii secretion
VCSRO5_1105	COG4792	protein secretion
VCSRO5_1111	COG3710	Transcriptional regulator
VCSRO5_1113	COG4790	Type iii secretion
VCSRO5_1128	COG0582	viral genome integration into host DNA
VCSRO5_1131	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO5_1133	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCSRO5_1133	COG3008	intermembrane lipid transfer
VCSRO5_1134	COG2995	paraquat-inducible protein a
VCSRO5_1135	COG0668	transmembrane transport
VCSRO5_1136	COG1309	transcriptional regulator
VCSRO5_1137	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO5_1141	COG1960	acyl-CoA dehydrogenase activity
VCSRO5_1142	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCSRO5_1143	COG3385	transposase activity
VCSRO5_1144	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VCSRO5_1145	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
VCSRO5_1146	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VCSRO5_1149	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCSRO5_1150	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCSRO5_1151	COG0297	glycogen (starch) synthase activity
VCSRO5_1155	COG3070	regulator of competence-specific genes
VCSRO5_1156	COG1609	Transcriptional regulator
VCSRO5_1158	COG0745	RESPONSE REGULATOR receiver
VCSRO5_1159	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCSRO5_1160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCSRO5_1161	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VCSRO5_1162	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VCSRO5_1164	COG1979	alcohol dehydrogenase
VCSRO5_1165	COG2207	Transcriptional regulator
VCSRO5_1169	COG1032	radical SAM domain protein
VCSRO5_1170	COG5001	Diguanylate cyclase
VCSRO5_1174	COG0583	DNA-binding transcription factor activity
VCSRO5_1175	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VCSRO5_1177	COG2350	Protein conserved in bacteria
VCSRO5_1178	COG1607	acyl-coa hydrolase
VCSRO5_1181	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCSRO5_1182	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCSRO5_1184	COG2116	formate transmembrane transporter activity
VCSRO5_1185	COG4459	periplasmic nitrate reductase
VCSRO5_1186	COG3005	denitrification pathway
VCSRO5_1187	COG0243	molybdopterin cofactor binding
VCSRO5_1188	COG0243	molybdopterin cofactor binding
VCSRO5_1191	COG1227	inorganic diphosphatase activity
VCSRO5_1194	COG4172	Belongs to the ABC transporter superfamily
VCSRO5_1197	COG4168	peptide transport system, permease
VCSRO5_1199	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VCSRO5_1200	COG1842	Phage shock protein A
VCSRO5_1203	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO5_1206	COG2818	Glycosylase
VCSRO5_1207	COG0626	cystathionine gamma-synthase activity
VCSRO5_1209	COG0733	neurotransmitter:sodium symporter activity
VCSRO5_1210	COG0564	pseudouridine synthase activity
VCSRO5_1211	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VCSRO5_1212	COG4136	ATPase activity
VCSRO5_1213	COG4135	transport system, permease component
VCSRO5_1214	COG4134	Bacterial extracellular solute-binding protein
VCSRO5_1216	COG3313	Fe-S protein
VCSRO5_1218	COG0842	Transport permease protein
VCSRO5_1219	COG1131	(ABC) transporter
VCSRO5_1220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO5_1221	COG0814	amino acid
VCSRO5_1224	COG2239	Acts as a magnesium transporter
VCSRO5_1225	COG0784	Response regulator, receiver
VCSRO5_1225	COG2205	protein histidine kinase activity
VCSRO5_1228	COG4934	collagen metabolic process
VCSRO5_1232	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
VCSRO5_1234	COG0840	transmembrane signaling receptor activity
VCSRO5_1236	COG2203	Gaf domain
VCSRO5_1236	COG3706	GGDEF domain
VCSRO5_1236	COG4251	negative regulation of phosphorylation
VCSRO5_1236	COG5001	Diguanylate cyclase
VCSRO5_1237	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VCSRO5_1241	COG1061	Type III restriction enzyme res subunit
VCSRO5_1242	COG1187	pseudouridine synthase activity
VCSRO5_1243	COG2814	Major facilitator Superfamily
VCSRO5_1245	COG0702	epimerase
VCSRO5_1246	COG0534	Mate efflux family protein
VCSRO5_1247	COG4181	ATPase activity
VCSRO5_1248	COG0577	efflux transmembrane transporter activity
VCSRO5_1250	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCSRO5_1252	COG1748	Saccharopine dehydrogenase
VCSRO5_1255	COG1538	Outer membrane efflux protein
VCSRO5_1257	COG3385	transposase activity
VCSRO5_1261	COG0583	DNA-binding transcription factor activity
VCSRO5_1263	COG1451	nucleotide metabolic process
VCSRO5_1266	COG3063	Type IV pilus biogenesis stability protein PilW
VCSRO5_1267	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VCSRO5_1271	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO5_1274	COG3290	protein histidine kinase activity
VCSRO5_1275	COG4565	transcriptional regulatory protein
VCSRO5_1277	COG0784	Response regulator, receiver
VCSRO5_1277	COG0835	chemotaxis
VCSRO5_1285	COG1085	galactose-1-phosphate uridylyltransferase
VCSRO5_1286	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VCSRO5_1287	COG2017	converts alpha-aldose to the beta-anomer
VCSRO5_1289	COG2199	diguanylate cyclase activity
VCSRO5_1289	COG2200	EAL domain
VCSRO5_1292	COG3527	Alpha-acetolactate decarboxylase
VCSRO5_1295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCSRO5_1300	COG3097	Belongs to the UPF0267 family
VCSRO5_1305	COG1271	oxidase subunit
VCSRO5_1306	COG1294	oxidase, subunit
VCSRO5_1307	COG1136	(ABC) transporter
VCSRO5_1307	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO5_1308	COG0577	efflux transmembrane transporter activity
VCSRO5_1308	COG1136	(ABC) transporter
VCSRO5_1309	COG0577	efflux transmembrane transporter activity
VCSRO5_1314	COG3385	transposase activity
VCSRO5_1316	COG2723	6-phospho-beta-galactosidase activity
VCSRO5_1317	COG1609	Transcriptional regulator
VCSRO5_1318	COG0251	oxidation-reduction process
VCSRO5_1319	COG2731	YhcH YjgK YiaL family protein
VCSRO5_1320	COG0584	glycerophosphoryl diester phosphodiesterase
VCSRO5_1321	COG1349	DNA-binding transcription factor activity
VCSRO5_1322	COG3842	ATPase activity
VCSRO5_1323	COG0395	ABC-type sugar transport system, permease component
VCSRO5_1324	COG1175	transmembrane transport
VCSRO5_1327	COG0811	peptide transport
VCSRO5_1328	COG0811	peptide transport
VCSRO5_1329	COG0848	biopolymer transport protein
VCSRO5_1330	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCSRO5_1332	COG1793	dna ligase
VCSRO5_1334	COG0534	Mate efflux family protein
VCSRO5_1336	COG3001	Fructosamine kinase
VCSRO5_1338	COG0791	NLP P60 protein
VCSRO5_1339	COG0840	transmembrane signaling receptor activity
VCSRO5_1341	COG3148	PFAM DTW domain containing protein
VCSRO5_1342	COG1940	carbohydrate kinase activity
VCSRO5_1344	COG0303	'Molybdopterin
VCSRO5_1345	COG0746	molybdenum cofactor guanylyltransferase activity
VCSRO5_1346	COG3842	ATPase activity
VCSRO5_1347	COG4662	Binding-protein-dependent transport system inner membrane component
VCSRO5_1349	COG2204	response regulator
VCSRO5_1350	COG3852	Histidine kinase
VCSRO5_1351	COG0488	(ABC) transporter
VCSRO5_1352	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VCSRO5_1358	COG0243	molybdopterin cofactor binding
VCSRO5_1358	COG3383	formate dehydrogenase (NAD+) activity
VCSRO5_1359	COG0437	4 iron, 4 sulfur cluster binding
VCSRO5_1362	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VCSRO5_1363	COG1666	GTP binding
VCSRO5_1364	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO5_1367	COG2996	Protein conserved in bacteria
VCSRO5_1369	COG3008	intermembrane lipid transfer
VCSRO5_1370	COG2995	paraquat-inducible protein a
VCSRO5_1371	COG1132	(ABC) transporter
VCSRO5_1372	COG1956	GAF domain-containing protein
VCSRO5_1373	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VCSRO5_1376	COG0308	aminopeptidase N
VCSRO5_1379	COG0167	dihydroorotate dehydrogenase activity
VCSRO5_1380	COG0167	dihydroorotate dehydrogenase activity
VCSRO5_1383	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCSRO5_1383	COG0116	Belongs to the methyltransferase superfamily
VCSRO5_1385	COG0488	(ABC) transporter
VCSRO5_1388	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCSRO5_1389	COG1067	ATP-dependent peptidase activity
VCSRO5_1390	COG3120	sequence-specific DNA binding
VCSRO5_1431	COG3064	Membrane
VCSRO5_1431	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VCSRO5_1431	COG1073	alpha beta
VCSRO5_1432	COG2994	toxin metabolic process
VCSRO5_1437	COG2205	protein histidine kinase activity
VCSRO5_1437	COG0784	Response regulator, receiver
VCSRO5_1440	COG3278	Belongs to the heme-copper respiratory oxidase family
VCSRO5_1443	COG2010	Cytochrome c
VCSRO5_1445	COG2217	Heavy metal translocating P-type atpase
VCSRO5_1448	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VCSRO5_1449	COG0589	response to stress
VCSRO5_1450	COG0037	tRNA processing
VCSRO5_1454	COG3842	ATPase activity
VCSRO5_1456	COG1177	transmembrane transport
VCSRO5_1458	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCSRO5_1461	COG1115	amino acid carrier protein
VCSRO5_1462	COG1280	lysine exporter protein (LysE YggA)
VCSRO5_1466	COG3501	Rhs element vgr protein
VCSRO5_1468	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VCSRO5_1469	COG0840	transmembrane signaling receptor activity
VCSRO5_1470	COG2814	Major facilitator Superfamily
VCSRO5_1471	COG1566	PFAM secretion protein HlyD family protein
VCSRO5_1474	COG0513	Belongs to the DEAD box helicase family
VCSRO5_1476	COG0840	transmembrane signaling receptor activity
VCSRO5_1477	COG0840	transmembrane signaling receptor activity
VCSRO5_1478	COG0835	chemotaxis
VCSRO5_1479	COG2201	protein-glutamate methylesterase activity
VCSRO5_1481	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCSRO5_1482	COG0643	Histidine kinase
VCSRO5_1482	COG0784	Response regulator, receiver
VCSRO5_1482	COG2198	Histidine kinase
VCSRO5_1483	COG2198	Histidine kinase
VCSRO5_1483	COG0643	Histidine kinase
VCSRO5_1485	COG0745	RESPONSE REGULATOR receiver
VCSRO5_1488	COG0415	Belongs to the DNA photolyase family
VCSRO5_1489	COG0477	Major facilitator Superfamily
VCSRO5_1490	COG0583	DNA-binding transcription factor activity
VCSRO5_1491	COG0402	S-adenosylhomocysteine deaminase activity
VCSRO5_1492	COG0095	Lipoate-protein ligase
VCSRO5_1493	COG0443	Heat shock 70 kDa protein
VCSRO5_1495	COG1643	Atp-dependent helicase
VCSRO5_1503	COG0443	Heat shock 70 kDa protein
VCSRO5_1504	COG3706	GGDEF domain
VCSRO5_1510	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VCSRO5_1511	COG0602	queuosine metabolic process
VCSRO5_1513	COG0561	phosphatase activity
VCSRO5_1515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO5_1516	COG4597	amino acid ABC transporter
VCSRO5_1517	COG0765	amino acid transport
VCSRO5_1518	COG1126	abc transporter atp-binding protein
VCSRO5_1519	COG0670	Belongs to the BI1 family
VCSRO5_1520	COG2920	part of a sulfur-relay system
VCSRO5_1521	COG1254	Belongs to the acylphosphatase family
VCSRO5_1522	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCSRO5_1523	COG3706	GGDEF domain
VCSRO5_1525	COG4999	Histidine kinase
VCSRO5_1525	COG3850	Histidine kinase
VCSRO5_1525	COG3437	response regulator, receiver
VCSRO5_1525	COG2205	protein histidine kinase activity
VCSRO5_1526	COG3437	response regulator, receiver
VCSRO5_1527	COG0625	glutathione transferase activity
VCSRO5_1529	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VCSRO5_1531	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO5_1537	COG0372	Belongs to the citrate synthase family
VCSRO5_1538	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VCSRO5_1546	COG1129	ABC transporter
VCSRO5_1551	COG0745	RESPONSE REGULATOR receiver
VCSRO5_1552	COG5002	protein histidine kinase activity
VCSRO5_1553	COG3713	MltA-interacting MipA family protein
VCSRO5_1554	COG2990	Protein conserved in bacteria
VCSRO5_1556	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO5_1556	COG4191	Histidine kinase
VCSRO5_1557	COG0471	metal ion transport
VCSRO5_1559	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCSRO5_1562	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO5_1564	COG3768	UPF0283 membrane protein
VCSRO5_1565	COG3106	COG3106 Predicted ATPase
VCSRO5_1568	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCSRO5_1569	COG0494	nUDIX hydrolase
VCSRO5_1570	COG0814	amino acid
VCSRO5_1571	COG1760	l-serine dehydratase
VCSRO5_1572	COG0720	synthase
VCSRO5_1573	COG0840	transmembrane signaling receptor activity
VCSRO5_1574	COG0017	Asparaginyl-tRNA synthetase
VCSRO5_1575	COG0351	phosphomethylpyrimidine kinase
VCSRO5_1576	COG2770	Histidine kinase
VCSRO5_1576	COG3437	response regulator, receiver
VCSRO5_1577	COG1448	Aminotransferase
VCSRO5_1580	COG0840	transmembrane signaling receptor activity
VCSRO5_1581	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
VCSRO5_1582	COG2943	transferase activity, transferring hexosyl groups
VCSRO5_1583	COG1609	Transcriptional regulator
VCSRO5_1584	COG3394	polysaccharide catabolic process
VCSRO5_1585	COG1486	melibiose metabolic process
VCSRO5_1586	COG1447	Phosphotransferase system cellobiose-specific component IIA
VCSRO5_1587	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VCSRO5_1588	COG3385	transposase activity
VCSRO5_1590	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VCSRO5_1591	COG0726	polysaccharide deacetylase
VCSRO5_1592	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VCSRO5_1593	COG1846	Transcriptional regulator
VCSRO5_1598	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCSRO5_1601	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCSRO5_1602	COG3108	Peptidase M15
VCSRO5_1608	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VCSRO5_1610	COG2814	Major facilitator Superfamily
VCSRO5_1612	COG1054	Belongs to the UPF0176 family
VCSRO5_1614	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCSRO5_1615	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCSRO5_1616	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCSRO5_1625	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
VCSRO5_1626	COG4139	cobalamin transport
VCSRO5_1627	COG2988	succinylglutamate desuccinylase activity
VCSRO5_1630	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VCSRO5_1631	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VCSRO5_1632	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO5_1634	COG1823	symporter activity
VCSRO5_1635	COG2925	Exonuclease
VCSRO5_1636	COG1380	Effector of murein hydrolase LrgA
VCSRO5_1637	COG1346	cytolysis
VCSRO5_1644	COG0776	regulation of translation
VCSRO5_1645	COG0072	phenylalanine-tRNA ligase activity
VCSRO5_1645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO5_1646	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VCSRO5_1654	COG0322	excinuclease ABC activity
VCSRO5_1655	COG2197	response regulator
VCSRO5_1656	COG0417	DNA replication proofreading
VCSRO5_1657	COG5001	Diguanylate cyclase
VCSRO5_1659	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCSRO5_1660	COG3099	Belongs to the UPF0263 family
VCSRO5_1663	COG1228	amidohydrolase
VCSRO5_1664	COG0010	Belongs to the arginase family
VCSRO5_1665	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VCSRO5_1666	COG2986	histidine ammonia-lyase
VCSRO5_1670	COG0247	lactate metabolic process
VCSRO5_1670	COG0277	FAD linked oxidase domain protein
VCSRO5_1673	COG2885	chlorophyll binding
VCSRO5_1677	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VCSRO5_1679	COG0281	malic enzyme
VCSRO5_1681	COG2949	membrane
VCSRO5_1683	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCSRO5_1685	COG0492	ferredoxin-NADP+ reductase activity
VCSRO5_1686	COG4988	ABC transporter
VCSRO5_1687	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VCSRO5_1688	COG1187	pseudouridine synthase activity
VCSRO5_1689	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO5_1690	COG0613	PHP domain protein
VCSRO5_1691	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCSRO5_1692	COG0512	Glutamine amidotransferase of anthranilate synthase
VCSRO5_1693	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VCSRO5_1694	COG0134	indole-3-glycerol-phosphate synthase activity
VCSRO5_1694	COG0135	phosphoribosylanthranilate isomerase activity
VCSRO5_1695	COG0133	tryptophan synthase activity
VCSRO5_1696	COG0159	tryptophan synthase activity
VCSRO5_1698	COG1435	thymidine kinase activity
VCSRO5_1699	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VCSRO5_1700	COG1801	Protein of unknown function DUF72
VCSRO5_1701	COG4106	trans-aconitate 2-methyltransferase activity
VCSRO5_1702	COG0500	methyltransferase
VCSRO5_1703	COG4067	protein conserved in archaea
VCSRO5_1703	COG0189	ligase activity
VCSRO5_1706	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VCSRO5_1708	COG3852	Histidine kinase
VCSRO5_1711	COG3070	regulator of competence-specific genes
VCSRO5_1713	COG2431	L-lysine efflux transmembrane transporter activity
VCSRO5_1715	COG0076	glutamate decarboxylase activity
VCSRO5_1716	COG1737	Transcriptional regulator
VCSRO5_1717	COG1454	alcohol dehydrogenase
VCSRO5_1717	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO5_1718	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCSRO5_1719	COG3273	potassium ion transport
VCSRO5_1719	COG2985	domain, Protein
VCSRO5_1720	COG0542	response to heat
VCSRO5_1721	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VCSRO5_1722	COG1278	Cold shock
VCSRO5_1724	COG1187	pseudouridine synthase activity
VCSRO5_1725	COG0140	phosphoribosyl-ATP diphosphatase activity
VCSRO5_1725	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VCSRO5_1726	COG0107	imidazoleglycerol-phosphate synthase activity
VCSRO5_1727	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VCSRO5_1728	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VCSRO5_1729	COG0131	Imidazoleglycerol-phosphate dehydratase
VCSRO5_1729	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCSRO5_1730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VCSRO5_1731	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VCSRO5_1732	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VCSRO5_1733	COG1757	Na H antiporter
VCSRO5_1734	COG2916	Histone family protein nucleoid-structuring protein H-NS
VCSRO5_1735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO5_1736	COG0482	sulfurtransferase activity
VCSRO5_1737	COG2915	High frequency lysogenization protein hflD homolog
VCSRO5_1738	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VCSRO5_1740	COG2268	Band 7 protein
VCSRO5_1742	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VCSRO5_1745	COG0300	oxidoreductase activity
VCSRO5_1747	COG0501	Belongs to the peptidase M48B family
VCSRO5_1749	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VCSRO5_1750	COG2226	methyltransferase
VCSRO5_1751	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO5_1752	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCSRO5_1754	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VCSRO5_1755	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VCSRO5_1756	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VCSRO5_1757	COG0653	protein targeting
VCSRO5_1758	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO5_1759	COG2203	Gaf domain
VCSRO5_1759	COG2199	diguanylate cyclase activity
VCSRO5_1761	COG4120	Belongs to the binding-protein-dependent transport system permease family
VCSRO5_1763	COG4628	conserved protein (DUF2132)
VCSRO5_1764	COG3092	negative regulation of chromosome organization
VCSRO5_1765	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCSRO5_1766	COG0857	belongs to the CobB CobQ family
VCSRO5_1766	COG0280	phosphate acetyltransferase
VCSRO5_1767	COG0435	Glutathione S-transferase
VCSRO5_1768	COG4608	Belongs to the ABC transporter superfamily
VCSRO5_1770	COG0444	Belongs to the ABC transporter superfamily
VCSRO5_1771	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO5_1772	COG0601	transmembrane transport
VCSRO5_1776	COG2204	response regulator
VCSRO5_1777	COG5001	Diguanylate cyclase
VCSRO5_1777	COG3300	MHYT domain
VCSRO5_1778	COG4191	Histidine kinase
VCSRO5_1779	COG5002	protein histidine kinase activity
VCSRO5_1781	COG2201	protein-glutamate methylesterase activity
VCSRO5_1784	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO5_1787	COG1881	PFAM PEBP family protein
VCSRO5_1793	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO5_1794	COG3716	PTS system mannose fructose sorbose family IID component
VCSRO5_1795	COG3715	PTS system
VCSRO5_1796	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO5_1797	COG2222	sugar isomerase
VCSRO5_1799	COG1349	DNA-binding transcription factor activity
VCSRO5_1800	COG1349	DNA-binding transcription factor activity
VCSRO5_1803	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO5_1804	COG0640	Transcriptional regulator
VCSRO5_1805	COG3706	GGDEF domain
VCSRO5_1809	COG1946	Acyl-CoA thioesterase
VCSRO5_1810	COG1522	sequence-specific DNA binding
VCSRO5_1812	COG0616	signal peptide processing
VCSRO5_1813	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO5_1815	COG2983	Belongs to the UPF0260 family
VCSRO5_1817	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VCSRO5_1818	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VCSRO5_1820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VCSRO5_1821	COG2832	Protein of unknown function (DUF454)
VCSRO5_1823	COG0745	RESPONSE REGULATOR receiver
VCSRO5_1824	COG0583	DNA-binding transcription factor activity
VCSRO5_1825	COG0778	Nitroreductase
VCSRO5_1826	COG1024	Enoyl-CoA hydratase
VCSRO5_1826	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCSRO5_1827	COG0183	Belongs to the thiolase family
VCSRO5_1830	COG2067	long-chain fatty acid transport protein
VCSRO5_1831	COG2067	long-chain fatty acid transport protein
VCSRO5_1833	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VCSRO5_1834	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VCSRO5_1835	COG2982	Protein involved in outer membrane biogenesis
VCSRO5_1836	COG0572	uridine kinase
VCSRO5_1837	COG0489	protein tyrosine kinase activity
VCSRO5_1838	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO5_1838	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO5_1840	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO5_1842	COG0517	IMP dehydrogenase activity
VCSRO5_1842	COG0617	tRNA 3'-terminal CCA addition
VCSRO5_1842	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
VCSRO5_1843	COG2199	diguanylate cyclase activity
VCSRO5_1844	COG0314	molybdopterin synthase activity
VCSRO5_1845	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VCSRO5_1846	COG0315	cyclic pyranopterin monophosphate synthase activity
VCSRO5_1847	COG0521	Mo-molybdopterin cofactor biosynthetic process
VCSRO5_1848	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VCSRO5_1849	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VCSRO5_1850	COG2198	Histidine kinase
VCSRO5_1851	COG2204	response regulator
VCSRO5_1852	COG0556	nucleotide-excision repair
VCSRO5_1854	COG4657	Part of a membrane complex involved in electron transport
VCSRO5_1855	COG2878	Part of a membrane complex involved in electron transport
VCSRO5_1856	COG4656	Part of a membrane complex involved in electron transport
VCSRO5_1859	COG4660	Part of a membrane complex involved in electron transport
VCSRO5_1860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VCSRO5_1861	COG0346	lactoylglutathione lyase activity
VCSRO5_1864	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VCSRO5_1865	COG2056	Na+-H+ antiporter family
VCSRO5_1866	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VCSRO5_1867	COG1286	toxin biosynthetic process
VCSRO5_1868	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VCSRO5_1869	COG0285	dihydrofolate synthase activity
VCSRO5_1870	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VCSRO5_1871	COG0101	tRNA pseudouridine synthase activity
VCSRO5_1874	COG2190	(PTS) system
VCSRO5_1874	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO5_1874	COG1263	PTS System
VCSRO5_1875	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VCSRO5_1876	COG1940	carbohydrate kinase activity
VCSRO5_1876	COG1846	Transcriptional regulator
VCSRO5_1877	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCSRO5_1877	COG4651	solute:proton antiporter activity
VCSRO5_1878	COG0367	asparagine synthase
VCSRO5_1881	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VCSRO5_1882	COG0563	adenylate kinase activity
VCSRO5_1883	COG0326	Molecular chaperone. Has ATPase activity
VCSRO5_1884	COG3710	Transcriptional regulator
VCSRO5_1887	COG0622	Phosphoesterase
VCSRO5_1888	COG1090	epimerase
VCSRO5_1889	COG0300	oxidoreductase activity
VCSRO5_1890	COG3118	belongs to the thioredoxin family
VCSRO5_1891	COG0330	HflC and HflK could
VCSRO5_1892	COG1585	Membrane protein implicated in regulation of membrane protease activity
VCSRO5_1893	COG0789	Transcriptional regulator
VCSRO5_1894	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCSRO5_1896	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VCSRO5_1897	COG3115	cell septum assembly
VCSRO5_1898	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VCSRO5_1899	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VCSRO5_1900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO5_1902	COG2190	(PTS) system
VCSRO5_1903	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO5_1904	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCSRO5_1905	COG1702	phosphate starvation-inducible protein PhoH
VCSRO5_1906	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VCSRO5_1907	COG4535	Mg2 and Co2 transporter CorC
VCSRO5_1908	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VCSRO5_1909	COG2888	peptidyl-tyrosine sulfation
VCSRO5_1910	COG0495	leucyl-tRNA aminoacylation
VCSRO5_1911	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VCSRO5_1912	COG1466	dna polymerase III delta subunit
VCSRO5_1913	COG0799	negative regulation of ribosome biogenesis
VCSRO5_1914	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VCSRO5_1915	COG0768	penicillin binding
VCSRO5_1916	COG0772	Belongs to the SEDS family
VCSRO5_1917	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCSRO5_1918	COG1686	Belongs to the peptidase S11 family
VCSRO5_1919	COG2921	Belongs to the UPF0250 family
VCSRO5_1920	COG0321	lipoyl(octanoyl) transferase activity
VCSRO5_1921	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VCSRO5_1923	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCSRO5_1928	COG1596	polysaccharide export
VCSRO5_1930	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCSRO5_1936	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
VCSRO5_1938	COG0438	transferase activity, transferring glycosyl groups
VCSRO5_1940	COG0297	glycogen (starch) synthase activity
VCSRO5_1944	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VCSRO5_1945	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VCSRO5_1948	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO5_1954	COG0366	Alpha amylase catalytic
VCSRO5_1955	COG1263	PTS System
VCSRO5_1955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO5_1956	COG1609	Transcriptional regulator
VCSRO5_1957	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCSRO5_1958	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VCSRO5_1959	COG2011	ABC-type metal ion transport system permease component
VCSRO5_1960	COG1464	Belongs to the NlpA lipoprotein family
VCSRO5_1961	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VCSRO5_1963	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCSRO5_1963	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCSRO5_1966	COG1611	Belongs to the LOG family
VCSRO5_1967	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO5_1968	COG2363	Small membrane protein
VCSRO5_1969	COG0583	DNA-binding transcription factor activity
VCSRO5_1970	COG0301	tRNA thio-modification
VCSRO5_1970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO5_1972	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VCSRO5_1973	COG1722	exodeoxyribonuclease VII activity
VCSRO5_1974	COG0142	geranyltranstransferase activity
VCSRO5_1975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VCSRO5_1976	COG0564	pseudouridine synthase activity
VCSRO5_1977	COG3098	single-species biofilm formation
VCSRO5_1980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO5_1982	COG1671	Belongs to the UPF0178 family
VCSRO5_1983	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCSRO5_1984	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCSRO5_1985	COG0254	rRNA binding
VCSRO5_1986	COG1720	tRNA m6t6A37 methyltransferase activity
VCSRO5_1987	COG0442	prolyl-tRNA aminoacylation
VCSRO5_1991	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VCSRO5_1991	COG0047	phosphoribosylformylglycinamidine synthase activity
VCSRO5_1992	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VCSRO5_1995	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCSRO5_2001	COG0484	heat shock protein binding
VCSRO5_2002	COG0443	Heat shock 70 kDa protein
VCSRO5_2003	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VCSRO5_2004	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VCSRO5_2005	COG0497	DNA recombination
VCSRO5_2006	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO5_2007	COG2914	Belongs to the UPF0125 (RnfH) family
VCSRO5_2008	COG2867	negative regulation of translational initiation
VCSRO5_2009	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VCSRO5_2011	COG0582	viral genome integration into host DNA
VCSRO5_2022	COG2003	Belongs to the UPF0758 family
VCSRO5_2025	COG0328	RNA-DNA hybrid ribonuclease activity
VCSRO5_2036	COG1396	sequence-specific DNA binding
VCSRO5_2043	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VCSRO5_2044	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VCSRO5_2045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCSRO5_2049	COG3051	citrate lyase alpha subunit
VCSRO5_2050	COG2301	Belongs to the HpcH HpaI aldolase family
VCSRO5_2051	COG3052	prosthetic group binding
VCSRO5_2052	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
VCSRO5_2054	COG3630	sodium ion export across plasma membrane
VCSRO5_2055	COG5016	pyruvate
VCSRO5_2055	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO5_2056	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCSRO5_2058	COG4565	transcriptional regulatory protein
VCSRO5_2063	COG1115	amino acid carrier protein
VCSRO5_2064	COG2977	Belongs to the P-Pant transferase superfamily
VCSRO5_2065	COG1120	ATPase activity
VCSRO5_2066	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO5_2067	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO5_2068	COG4592	Periplasmic binding protein
VCSRO5_2070	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO5_2071	COG1169	isochorismate synthase
VCSRO5_2072	COG1021	2,3-dihydroxybenzoate-AMP ligase
VCSRO5_2073	COG1535	isochorismatase
VCSRO5_2073	COG3433	isochorismatase activity
VCSRO5_2074	COG1584	GPR1 FUN34 yaaH family protein
VCSRO5_2076	COG0519	Catalyzes the synthesis of GMP from XMP
VCSRO5_2076	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VCSRO5_2077	COG0516	GMP reductase activity
VCSRO5_2077	COG0517	IMP dehydrogenase activity
VCSRO5_2078	COG1570	exodeoxyribonuclease VII activity
VCSRO5_2081	COG1160	GTP binding
VCSRO5_2082	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO5_2083	COG2976	Protein conserved in bacteria
VCSRO5_2084	COG0124	histidyl-tRNA synthetase
VCSRO5_2085	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VCSRO5_2088	COG0105	UTP biosynthetic process
VCSRO5_2089	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCSRO5_2090	COG2975	iron-sulfur cluster assembly
VCSRO5_2091	COG0633	Ferredoxin
VCSRO5_2092	COG0443	Heat shock 70 kDa protein
VCSRO5_2095	COG0822	iron-sulfur transferase activity
VCSRO5_2097	COG1959	2 iron, 2 sulfur cluster binding
VCSRO5_2099	COG0483	inositol monophosphate 1-phosphatase activity
VCSRO5_2100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO5_2101	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO5_2102	COG1862	Preprotein translocase
VCSRO5_2104	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
VCSRO5_2105	COG0517	IMP dehydrogenase activity
VCSRO5_2107	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VCSRO5_2108	COG0583	DNA-binding transcription factor activity
VCSRO5_2109	COG0450	alkyl hydroperoxide reductase
VCSRO5_2110	COG3142	Participates in the control of copper homeostasis
VCSRO5_2113	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCSRO5_2114	COG0581	inorganic phosphate transmembrane transporter activity
VCSRO5_2116	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VCSRO5_2117	COG0248	Ppx GppA phosphatase
VCSRO5_2119	COG5002	protein histidine kinase activity
VCSRO5_2120	COG0745	RESPONSE REGULATOR receiver
VCSRO5_2122	COG0826	peptidase U32
VCSRO5_2123	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCSRO5_2132	COG0542	response to heat
VCSRO5_2134	COG0564	pseudouridine synthase activity
VCSRO5_2135	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO5_2136	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCSRO5_2137	COG1605	Chorismate mutase
VCSRO5_2137	COG0077	Prephenate dehydratase
VCSRO5_2138	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCSRO5_2139	COG5001	Diguanylate cyclase
VCSRO5_2141	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VCSRO5_2143	COG0488	(ABC) transporter
VCSRO5_2145	COG1605	Chorismate mutase
VCSRO5_2145	COG0287	Prephenate dehydrogenase
VCSRO5_2146	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO5_2147	COG3275	phosphorelay sensor kinase activity
VCSRO5_2148	COG3279	Response regulator of the LytR AlgR family
VCSRO5_2150	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VCSRO5_2151	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCSRO5_2154	COG1966	Carbon starvation protein
VCSRO5_2155	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VCSRO5_2156	COG1047	Peptidyl-prolyl cis-trans
VCSRO5_2157	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VCSRO5_2159	COG0196	riboflavin kinase activity
VCSRO5_2160	COG0728	peptidoglycan biosynthetic process
VCSRO5_2161	COG0268	Binds directly to 16S ribosomal RNA
VCSRO5_2162	COG0640	Transcriptional regulator
VCSRO5_2163	COG0583	DNA-binding transcription factor activity
VCSRO5_2164	COG1283	sodium-dependent phosphate transmembrane transporter activity
VCSRO5_2165	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
VCSRO5_2166	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VCSRO5_2167	COG0730	response to heat
VCSRO5_2169	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
VCSRO5_2170	COG0494	nUDIX hydrolase
VCSRO5_2172	COG0667	Aldo Keto reductase
VCSRO5_2175	COG2204	response regulator
VCSRO5_2176	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VCSRO5_2177	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VCSRO5_2180	COG0513	Belongs to the DEAD box helicase family
VCSRO5_2185	COG3153	acetyltransferase
VCSRO5_2186	COG3154	lipid carrier protein
VCSRO5_2188	COG0826	peptidase U32
VCSRO5_2189	COG0826	peptidase U32
VCSRO5_2194	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VCSRO5_2196	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VCSRO5_2197	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VCSRO5_2198	COG0195	Participates in both transcription termination and antitermination
VCSRO5_2199	COG0779	Required for maturation of 30S ribosomal subunits
VCSRO5_2202	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCSRO5_2205	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VCSRO5_2206	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VCSRO5_2207	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VCSRO5_2208	COG1534	Rna-binding protein
VCSRO5_2209	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO5_2211	COG2027	D-alanyl-D-alanine carboxypeptidase
VCSRO5_2212	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCSRO5_2213	COG0739	heme binding
VCSRO5_2216	COG0316	Belongs to the HesB IscA family
VCSRO5_2217	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VCSRO5_2219	COG0628	permease
VCSRO5_2220	COG2813	Specifically methylates the guanine in position
VCSRO5_2221	COG0784	Response regulator, receiver
VCSRO5_2221	COG2205	protein histidine kinase activity
VCSRO5_2222	COG0747	negative chemotaxis
VCSRO5_2224	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO5_2225	COG0444	Belongs to the ABC transporter superfamily
VCSRO5_2226	COG4608	Belongs to the ABC transporter superfamily
VCSRO5_2228	COG2971	BadF BadG BcrA BcrD
VCSRO5_2231	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCSRO5_2232	COG3842	ATPase activity
VCSRO5_2234	COG1840	ABC-type Fe3 transport system, periplasmic component
VCSRO5_2235	COG0004	ammonium transporteR
VCSRO5_2236	COG0347	Belongs to the P(II) protein family
VCSRO5_2237	COG3112	Uncharacterised protein family (UPF0231)
VCSRO5_2238	COG1049	propionate catabolic process, 2-methylcitrate cycle
VCSRO5_2239	COG1752	Esterase of the alpha-beta hydrolase superfamily
VCSRO5_2241	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VCSRO5_2242	COG1643	Atp-dependent helicase
VCSRO5_2244	COG1489	DNA binding
VCSRO5_2246	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCSRO5_2248	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCSRO5_2249	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VCSRO5_2250	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VCSRO5_2251	COG0842	Transport permease protein
VCSRO5_2252	COG1131	(ABC) transporter
VCSRO5_2253	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO5_2254	COG0288	reversible hydration of carbon dioxide
VCSRO5_2258	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VCSRO5_2259	COG3107	peptidoglycan biosynthetic process
VCSRO5_2260	COG0792	nuclease activity
VCSRO5_2261	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCSRO5_2262	COG2823	Periplasmic or secreted lipoprotein
VCSRO5_2263	COG2969	positive regulation of protein catabolic process
VCSRO5_2264	COG0625	glutathione transferase activity
VCSRO5_2265	COG2857	Cytochrome c1
VCSRO5_2266	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VCSRO5_2267	COG0723	plastoquinol--plastocyanin reductase activity
VCSRO5_2268	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VCSRO5_2269	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VCSRO5_2270	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VCSRO5_2272	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCSRO5_2273	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCSRO5_2274	COG0335	large ribosomal subunit rRNA binding
VCSRO5_2275	COG0336	Belongs to the RNA methyltransferase TrmD family
VCSRO5_2276	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VCSRO5_2277	COG0228	four-way junction DNA binding
VCSRO5_2278	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VCSRO5_2280	COG4137	Cytochrome C assembly protein
VCSRO5_2281	COG4536	flavin adenine dinucleotide binding
VCSRO5_2282	COG1854	S-ribosylhomocysteine lyase activity
VCSRO5_2283	COG2918	glutathione biosynthetic process
VCSRO5_2284	COG0612	Peptidase, M16
VCSRO5_2285	COG1238	metal cluster binding
VCSRO5_2287	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCSRO5_2288	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO5_2288	COG5016	pyruvate
VCSRO5_2289	COG3630	sodium ion export across plasma membrane
VCSRO5_2298	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
VCSRO5_2299	COG0527	aspartate kinase activity
VCSRO5_2300	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VCSRO5_2301	COG2137	regulation of response to DNA damage stimulus
VCSRO5_2302	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VCSRO5_2304	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
VCSRO5_2305	COG4208	sulfate ABC transporter
VCSRO5_2309	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VCSRO5_2310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCSRO5_2312	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VCSRO5_2313	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VCSRO5_2314	COG0585	pseudouridine synthase activity
VCSRO5_2315	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VCSRO5_2316	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VCSRO5_2317	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VCSRO5_2318	COG1968	undecaprenyl-diphosphatase activity
VCSRO5_2319	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCSRO5_2320	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VCSRO5_2321	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VCSRO5_2323	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VCSRO5_2324	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VCSRO5_2325	COG1610	YqeY-like protein
VCSRO5_2326	COG0358	DNA primase activity
VCSRO5_2332	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VCSRO5_2346	COG1196	nuclear chromosome segregation
VCSRO5_2348	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCSRO5_2349	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VCSRO5_2350	COG1349	DNA-binding transcription factor activity
VCSRO5_2355	COG1279	arginine transmembrane transporter activity
VCSRO5_2356	COG0668	transmembrane transport
VCSRO5_2357	COG0191	fructose-bisphosphate aldolase activity
VCSRO5_2358	COG0126	phosphoglycerate kinase activity
VCSRO5_2359	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO5_2360	COG4771	TonB-dependent receptor
VCSRO5_2361	COG0583	DNA-binding transcription factor activity
VCSRO5_2362	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCSRO5_2363	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VCSRO5_2365	COG2356	endonuclease I
VCSRO5_2366	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VCSRO5_2367	COG0189	ligase activity
VCSRO5_2368	COG1678	Uncharacterized ACR, COG1678
VCSRO5_2369	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VCSRO5_2370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCSRO5_2374	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VCSRO5_2375	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VCSRO5_2376	COG0762	integral membrane protein
VCSRO5_2377	COG1872	DUF167
VCSRO5_2379	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VCSRO5_2380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VCSRO5_2381	COG2066	Belongs to the glutaminase family
VCSRO5_2382	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VCSRO5_2383	COG1194	a g-specific adenine glycosylase
VCSRO5_2384	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VCSRO5_2385	COG0741	lytic transglycosylase activity
VCSRO5_2390	COG0840	transmembrane signaling receptor activity
VCSRO5_2396	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VCSRO5_2397	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VCSRO5_2398	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO5_2399	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VCSRO5_2400	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VCSRO5_2401	COG2967	ApaG domain
VCSRO5_2402	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VCSRO5_2404	COG3610	response to peptide
VCSRO5_2405	COG2966	Psort location CytoplasmicMembrane, score
VCSRO5_2406	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VCSRO5_2407	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VCSRO5_2408	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VCSRO5_2409	COG0142	geranyltranstransferase activity
VCSRO5_2410	COG0531	amino acid
VCSRO5_2411	COG0039	L-malate dehydrogenase activity
VCSRO5_2412	COG1438	arginine binding
VCSRO5_2413	COG2358	TRAP transporter, solute receptor (TAXI family
VCSRO5_2415	COG0589	response to stress
VCSRO5_2419	COG2235	arginine
VCSRO5_2420	COG0312	modulator of DNA gyrase
VCSRO5_2421	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VCSRO5_2422	COG3164	Protein of unknown function
VCSRO5_2424	COG0424	maF-like protein
VCSRO5_2425	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VCSRO5_2426	COG1792	Involved in formation and maintenance of cell shape
VCSRO5_2427	COG1077	Cell shape determining protein MreB Mrl
VCSRO5_2433	COG2165	general secretion pathway protein
VCSRO5_2434	COG2165	general secretion pathway protein
VCSRO5_2436	COG1459	type II secretion system
VCSRO5_2437	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO5_2439	COG3267	Type II secretory pathway component ExeA
VCSRO5_2439	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO5_2445	COG2199	diguanylate cyclase activity
VCSRO5_2445	COG2200	EAL domain
VCSRO5_2446	COG0629	single-stranded DNA binding
VCSRO5_2449	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VCSRO5_2451	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCSRO5_2452	COG0527	aspartate kinase activity
VCSRO5_2453	COG0646	methionine synthase
VCSRO5_2453	COG1410	methionine synthase
VCSRO5_2460	COG0175	sulfate reduction
VCSRO5_2462	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCSRO5_2466	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO5_2467	COG0735	belongs to the Fur family
VCSRO5_2470	COG0166	Belongs to the GPI family
VCSRO5_2471	COG0432	Pfam Uncharacterised protein family UPF0047
VCSRO5_2472	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCSRO5_2475	COG0359	binds to the 23S rRNA
VCSRO5_2476	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
VCSRO5_2477	COG2965	DNA replication, synthesis of RNA primer
VCSRO5_2478	COG0360	Binds together with S18 to 16S ribosomal RNA
VCSRO5_2480	COG2906	2 iron, 2 sulfur cluster binding
VCSRO5_2481	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCSRO5_2482	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCSRO5_2483	COG0049	tRNA binding
VCSRO5_2486	COG2923	Belongs to the DsrF TusC family
VCSRO5_2487	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VCSRO5_2488	COG2964	Protein conserved in bacteria
VCSRO5_2489	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO5_2491	COG2900	Belongs to the SlyX family
VCSRO5_2492	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VCSRO5_2493	COG0330	HflC and HflK could
VCSRO5_2494	COG0330	HflC and HflK could
VCSRO5_2495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VCSRO5_2496	COG1923	regulation of RNA biosynthetic process
VCSRO5_2497	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VCSRO5_2498	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VCSRO5_2500	COG0802	atpase or kinase
VCSRO5_2501	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VCSRO5_2511	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VCSRO5_2512	COG1162	GTPase activity
VCSRO5_2513	COG0688	phosphatidylethanolamine metabolic process
VCSRO5_2514	COG0471	metal ion transport
VCSRO5_2516	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VCSRO5_2517	COG4942	peptidase
VCSRO5_2520	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VCSRO5_2521	COG2816	NAD+ diphosphatase activity
VCSRO5_2522	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VCSRO5_2524	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VCSRO5_2525	COG0085	RNA polymerase activity
VCSRO5_2526	COG0222	ribosome binding
VCSRO5_2527	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VCSRO5_2529	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VCSRO5_2530	COG0250	Participates in transcription elongation, termination and antitermination
VCSRO5_2531	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCSRO5_2532	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCSRO5_2537	COG1072	(Pantothenic acid kinase))
VCSRO5_2539	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VCSRO5_2541	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VCSRO5_2557	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VCSRO5_2560	COG3118	belongs to the thioredoxin family
VCSRO5_2561	COG0513	Belongs to the DEAD box helicase family
VCSRO5_2562	COG0248	Ppx GppA phosphatase
VCSRO5_2563	COG2205	protein histidine kinase activity
VCSRO5_2563	COG0784	Response regulator, receiver
VCSRO5_2564	COG2814	Major facilitator Superfamily
VCSRO5_2567	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCSRO5_2568	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VCSRO5_2569	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO5_2570	COG0439	Biotin carboxylase
VCSRO5_2571	COG2264	protein methyltransferase activity
VCSRO5_2572	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO5_2573	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VCSRO5_2574	COG1609	Transcriptional regulator
VCSRO5_2575	COG0129	dihydroxy-acid dehydratase activity
VCSRO5_2576	COG3265	gluconokinase activity
VCSRO5_2577	COG2610	gluconate transmembrane transporter activity
VCSRO5_2578	COG0800	Aldolase
VCSRO5_2581	COG0840	transmembrane signaling receptor activity
VCSRO5_2582	COG1982	Orn Lys Arg decarboxylase major
VCSRO5_2583	COG0531	amino acid
VCSRO5_2584	COG3710	Transcriptional regulator
VCSRO5_2585	COG0789	Transcriptional regulator
VCSRO5_2587	COG0151	Belongs to the GarS family
VCSRO5_2589	COG0776	regulation of translation
VCSRO5_2590	COG1253	flavin adenine dinucleotide binding
VCSRO5_2598	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO5_2599	COG3068	Protein conserved in bacteria
VCSRO5_2601	COG1573	uracil-dna glycosylase
VCSRO5_2602	COG0668	transmembrane transport
VCSRO5_2605	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VCSRO5_2606	COG3385	transposase activity
VCSRO5_2608	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VCSRO5_2610	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCSRO5_2611	COG0438	transferase activity, transferring glycosyl groups
VCSRO5_2622	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VCSRO5_2623	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VCSRO5_2625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCSRO5_2630	COG0859	PFAM glycosyl transferase family 9
VCSRO5_2632	COG1519	Transferase
VCSRO5_2638	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
VCSRO5_2638	COG2755	lipolytic protein G-D-S-L family
VCSRO5_2639	COG3642	lipopolysaccharide core region biosynthetic process
VCSRO5_2640	COG0859	PFAM glycosyl transferase family 9
VCSRO5_2641	COG0463	Glycosyl transferase, family 2
VCSRO5_2642	COG0859	PFAM glycosyl transferase family 9
VCSRO5_2643	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VCSRO5_2644	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VCSRO5_2646	COG0267	Belongs to the bacterial ribosomal protein bL33 family
VCSRO5_2647	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VCSRO5_2648	COG2003	Belongs to the UPF0758 family
VCSRO5_2650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VCSRO5_2651	COG1309	transcriptional regulator
VCSRO5_2652	COG1560	Kdo2-lipid A biosynthetic process
VCSRO5_2653	COG1560	Kdo2-lipid A biosynthetic process
VCSRO5_2654	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VCSRO5_2655	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VCSRO5_2656	COG1561	YicC-like family, N-terminal region
VCSRO5_2657	COG2862	Uncharacterized protein family, UPF0114
VCSRO5_2658	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO5_2658	COG1263	PTS System
VCSRO5_2659	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCSRO5_2663	COG1120	ATPase activity
VCSRO5_2664	COG4774	siderophore transport
VCSRO5_2665	COG1132	(ABC) transporter
VCSRO5_2668	COG0514	ATP-dependent DNA helicase (RecQ)
VCSRO5_2669	COG2962	Rard protein
VCSRO5_2670	COG0405	Gamma-glutamyltransferase
VCSRO5_2672	COG1280	lysine exporter protein (LysE YggA)
VCSRO5_2673	COG0210	DNA helicase
VCSRO5_2675	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VCSRO5_2676	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO5_2678	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO5_2679	COG0601	transmembrane transport
VCSRO5_2680	COG0747	negative chemotaxis
VCSRO5_2689	COG1309	transcriptional regulator
VCSRO5_2690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO5_2691	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO5_2692	COG2960	long-chain fatty acid transporting porin activity
VCSRO5_2693	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VCSRO5_2694	COG0583	DNA-binding transcription factor activity
VCSRO5_2702	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
VCSRO5_2703	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCSRO5_2704	COG1739	Uncharacterized protein family UPF0029
VCSRO5_2705	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCSRO5_2705	COG1024	Enoyl-CoA hydratase
VCSRO5_2706	COG0183	Belongs to the thiolase family
VCSRO5_2707	COG0583	DNA-binding transcription factor activity
VCSRO5_2708	COG2814	Major facilitator Superfamily
VCSRO5_2710	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VCSRO5_2711	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VCSRO5_2712	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VCSRO5_2713	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VCSRO5_2714	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VCSRO5_2715	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VCSRO5_2717	COG0356	it plays a direct role in the translocation of protons across the membrane
VCSRO5_2718	COG3312	ion transport
VCSRO5_2719	COG1475	DNA binding
VCSRO5_2720	COG1192	Involved in chromosome partitioning
VCSRO5_2721	COG0357	Ribosomal RNA small subunit methyltransferase G
VCSRO5_2722	COG0445	tRNA wobble uridine modification
VCSRO5_2727	COG0217	transcriptional regulatory protein
VCSRO5_2728	COG2084	Dehydrogenase
VCSRO5_2731	COG2909	trisaccharide binding
VCSRO5_2732	COG0058	SHG alpha-glucan phosphorylase activity
VCSRO5_2733	COG1640	4-alpha-glucanotransferase
VCSRO5_2734	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VCSRO5_2736	COG3501	Rhs element vgr protein
VCSRO5_2740	COG3788	relative of glutathione S-transferase, MAPEG superfamily
VCSRO5_2743	COG0471	metal ion transport
VCSRO5_2744	COG3385	transposase activity
VCSRO5_2745	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCSRO5_2754	COG0671	phosphoesterase, PA-phosphatase related
VCSRO5_2755	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VCSRO5_2757	COG1999	signal sequence binding
VCSRO5_2760	COG0786	glutamate:sodium symporter activity
VCSRO5_2767	COG0813	purine-nucleoside phosphorylase activity
VCSRO5_2768	COG3272	Protein of unknown function (DUF1722)
VCSRO5_2770	COG0415	Belongs to the DNA photolyase family
VCSRO5_2771	COG1376	ErfK ybiS ycfS ynhG family protein
VCSRO5_2771	COG1388	LysM domain
VCSRO5_2773	COG0513	Belongs to the DEAD box helicase family
VCSRO5_2774	COG1770	oligopeptidase
VCSRO5_2779	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCSRO5_2780	COG0573	inorganic phosphate transmembrane transporter activity
VCSRO5_2781	COG0581	inorganic phosphate transmembrane transporter activity
VCSRO5_2782	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCSRO5_2786	COG3314	Sporulation integral membrane protein YlbJ
VCSRO5_2787	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO5_2789	COG0739	heme binding
VCSRO5_2790	COG5001	Diguanylate cyclase
VCSRO5_2790	COG3300	MHYT domain
VCSRO5_2791	COG0583	DNA-binding transcription factor activity
VCSRO5_2792	COG2814	Major facilitator Superfamily
VCSRO5_2797	COG1301	dicarboxylic acid transport
VCSRO5_2799	COG1342	Belongs to the UPF0251 family
VCSRO5_2804	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VCSRO5_2805	COG0673	inositol 2-dehydrogenase activity
VCSRO5_2807	COG2200	EAL domain
VCSRO5_2807	COG2771	luxR family
VCSRO5_2808	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO5_2810	COG0564	pseudouridine synthase activity
VCSRO5_2823	COG3829	transcription factor binding
VCSRO5_2828	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO5_2828	COG3501	Rhs element vgr protein
VCSRO5_2831	COG1869	D-ribose catabolic process
VCSRO5_2832	COG1129	ABC transporter
VCSRO5_2833	COG1172	Belongs to the binding-protein-dependent transport system permease family
VCSRO5_2834	COG1879	ABC-type sugar transport system periplasmic component
VCSRO5_2835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO5_2836	COG1609	Transcriptional regulator
VCSRO5_2838	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO5_2840	COG0584	glycerophosphoryl diester phosphodiesterase
VCSRO5_2841	COG2271	Major facilitator Superfamily
VCSRO5_2848	COG0579	oxidoreductase
VCSRO5_2852	COG0242	peptide deformylase activity
VCSRO5_2853	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCSRO5_2853	COG1017	nitric oxide dioxygenase activity
VCSRO5_2854	COG1320	monovalent cation:proton antiporter activity
VCSRO5_2855	COG2212	antiporter activity
VCSRO5_2856	COG1863	multisubunit Na H antiporter MnhE subunit
VCSRO5_2857	COG0651	ATP synthesis coupled electron transport
VCSRO5_2858	COG1006	Multisubunit Na H antiporter MnhC subunit
VCSRO5_2859	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCSRO5_2859	COG2111	Na H antiporter
VCSRO5_2861	COG0589	response to stress
VCSRO5_2862	COG0814	amino acid
VCSRO5_2865	COG3530	Putative quorum-sensing-regulated virulence factor
VCSRO5_2867	COG5002	protein histidine kinase activity
VCSRO5_2867	COG5001	Diguanylate cyclase
VCSRO5_2868	COG1278	Cold shock
VCSRO5_2871	COG2304	oxidoreductase activity
VCSRO5_2875	COG0714	Associated with various cellular activities
VCSRO5_2876	COG0840	transmembrane signaling receptor activity
VCSRO5_2879	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO5_2880	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO5_2882	COG3604	Transcriptional regulator
VCSRO5_2883	COG1017	nitric oxide dioxygenase activity
VCSRO5_2883	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCSRO5_2884	COG1278	Cold shock
VCSRO5_2885	COG3036	rescue of stalled ribosome
VCSRO5_2890	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VCSRO5_2890	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VCSRO5_2891	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCSRO5_2893	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCSRO5_2895	COG0516	GMP reductase activity
VCSRO5_2897	COG0513	Belongs to the DEAD box helicase family
VCSRO5_2898	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCSRO5_2899	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VCSRO5_2900	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VCSRO5_2901	COG3437	response regulator, receiver
VCSRO5_2901	COG0784	Response regulator, receiver
VCSRO5_2902	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO5_2902	COG4191	Histidine kinase
VCSRO5_2904	COG1757	Na H antiporter
VCSRO5_2905	COG2814	Major facilitator Superfamily
VCSRO5_2907	COG3706	GGDEF domain
VCSRO5_2908	COG3240	lipase activity
VCSRO5_2910	COG0840	transmembrane signaling receptor activity
VCSRO5_2911	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VCSRO5_2912	COG5380	lipid catabolic process
VCSRO5_2917	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO5_2918	COG4605	iron ion homeostasis
VCSRO5_2919	COG4604	ABC transporter, ATP-binding protein
VCSRO5_2920	COG2207	Transcriptional regulator
VCSRO5_2923	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCSRO5_2927	COG0745	RESPONSE REGULATOR receiver
VCSRO5_2929	COG3623	hexulose-6-phosphate isomerase
VCSRO5_2930	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
VCSRO5_2931	COG0561	phosphatase activity
VCSRO5_2938	COG0366	Alpha amylase catalytic
VCSRO5_2942	COG0745	RESPONSE REGULATOR receiver
VCSRO5_2949	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VCSRO5_2952	COG0583	DNA-binding transcription factor activity
VCSRO5_2956	COG1686	Belongs to the peptidase S11 family
VCSRO5_2961	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCSRO5_2961	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCSRO5_2962	COG0509	glycine decarboxylation via glycine cleavage system
VCSRO5_2963	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCSRO5_2965	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VCSRO5_2968	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VCSRO5_2969	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
VCSRO5_2971	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
VCSRO5_2975	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
VCSRO5_2986	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO5_2992	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO5_3008	COG0456	acetyltransferase
VCSRO5_3009	COG0384	phenazine biosynthesis protein PhzF
VCSRO5_3010	COG0384	phenazine biosynthesis protein PhzF
VCSRO5_3023	COG0346	lactoylglutathione lyase activity
VCSRO5_3038	COG5642	Protein of unknown function (DUF2384)
VCSRO5_3051	COG0110	maltose O-acetyltransferase activity
VCSRO5_3062	COG0456	acetyltransferase
VCSRO5_3064	COG0494	nUDIX hydrolase
VCSRO5_3065	COG3041	Addiction module toxin RelE StbE family
VCSRO5_3070	COG0384	phenazine biosynthesis protein PhzF
VCSRO5_3071	COG0384	phenazine biosynthesis protein PhzF
VCSRO5_3089	COG1328	CTP reductase activity
VCSRO5_3090	COG0602	queuosine metabolic process
VCSRO5_3092	COG0189	ligase activity
VCSRO5_3092	COG4067	protein conserved in archaea
VCSRO5_3093	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VCSRO5_3093	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO5_3093	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO5_3094	COG1105	Belongs to the carbohydrate kinase PfkB family
VCSRO5_3095	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO5_3095	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO5_3096	COG1609	Transcriptional regulator
VCSRO5_3097	COG0420	3'-5' exonuclease activity
VCSRO5_3098	COG0419	ATPase involved in DNA repair
VCSRO5_3099	COG0784	Response regulator, receiver
VCSRO5_3099	COG2205	protein histidine kinase activity
VCSRO5_3100	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO5_3102	COG0038	chloride channel
VCSRO5_3103	COG0523	cobalamin synthesis protein
VCSRO5_3105	COG3158	transport of potassium into the cell
VCSRO5_3106	COG0674	pyruvate-flavodoxin oxidoreductase activity
VCSRO5_3106	COG1013	pyruvate-flavodoxin oxidoreductase activity
VCSRO5_3106	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
VCSRO5_3106	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VCSRO5_3107	COG2205	protein histidine kinase activity
VCSRO5_3108	COG0745	RESPONSE REGULATOR receiver
VCSRO5_3109	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO5_3110	COG0586	Pfam SNARE associated Golgi protein
VCSRO5_3112	COG2200	EAL domain
VCSRO5_3114	COG3038	cytochrome b561
VCSRO5_3116	COG2116	formate transmembrane transporter activity
VCSRO5_3117	COG0583	DNA-binding transcription factor activity
VCSRO5_3119	COG3593	DNA synthesis involved in DNA repair
VCSRO5_3120	COG0737	Belongs to the 5'-nucleotidase family
VCSRO5_3122	COG0861	Integral membrane protein TerC family
VCSRO5_3124	COG3385	transposase activity
VCSRO5_3125	COG2824	Alkylphosphonate utilization operon protein PhnA
VCSRO5_3131	COG2199	diguanylate cyclase activity
VCSRO5_3138	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VCSRO5_3139	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VCSRO5_3141	COG0745	RESPONSE REGULATOR receiver
VCSRO5_3144	COG3140	Belongs to the UPF0181 family
VCSRO5_3145	COG0023	Translation Initiation Factor
VCSRO5_3149	COG0045	succinate-CoA ligase (ADP-forming) activity
VCSRO5_3149	COG1042	CoA-binding domain protein
VCSRO5_3149	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO5_3150	COG0583	DNA-binding transcription factor activity
VCSRO5_3151	COG4771	TonB-dependent receptor
VCSRO5_3154	COG2050	protein possibly involved in aromatic compounds catabolism
VCSRO5_3158	COG0625	glutathione transferase activity
VCSRO5_3161	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VCSRO5_3162	COG4172	Belongs to the ABC transporter superfamily
VCSRO5_3163	COG4239	(ABC) transporter, permease
VCSRO5_3164	COG4174	ABC transporter (Permease)
VCSRO5_3165	COG4166	transmembrane transport
VCSRO5_3171	COG3104	oligopeptide transport
VCSRO5_3175	COG3842	ATPase activity
VCSRO5_3177	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCSRO5_3178	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VCSRO5_3179	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO5_3180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO5_3181	COG1011	Hydrolase
VCSRO5_3184	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VCSRO5_3185	COG1970	mechanosensitive ion channel activity
VCSRO5_3186	COG2759	Belongs to the formate--tetrahydrofolate ligase family
VCSRO5_3187	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO5_3187	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO5_3188	COG0302	gtp cyclohydrolase
VCSRO5_3190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCSRO5_3192	COG2897	thiosulfate sulfurtransferase activity
VCSRO5_3193	COG2390	Transcriptional regulator
VCSRO5_3195	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCSRO5_3201	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO5_3206	COG0583	DNA-binding transcription factor activity
VCSRO5_3207	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
VCSRO5_3215	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCSRO5_3224	COG1263	PTS System
VCSRO5_3224	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO5_3225	COG1609	Transcriptional regulator
VCSRO5_3226	COG1621	beta-fructofuranosidase activity
VCSRO5_3227	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO5_3228	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCSRO5_3229	COG0840	transmembrane signaling receptor activity
VCSRO5_3230	COG2885	chlorophyll binding
VCSRO5_3231	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO5_3232	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO5_3233	COG0840	transmembrane signaling receptor activity
VCSRO5_3234	COG3069	C4-dicarboxylate transmembrane transporter activity
VCSRO5_3235	COG1760	l-serine dehydratase
VCSRO5_3240	COG1609	Transcriptional regulator
VCSRO5_3241	COG2197	response regulator
VCSRO5_3242	COG3850	Histidine kinase
VCSRO5_3243	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCSRO5_3245	COG0243	molybdopterin cofactor binding
VCSRO5_3249	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO5_3250	COG2197	response regulator
VCSRO5_3251	COG3851	Histidine kinase
VCSRO5_3252	COG2271	Major facilitator Superfamily
VCSRO5_3253	COG1840	ABC-type Fe3 transport system, periplasmic component
VCSRO5_3255	COG3842	ATPase activity
VCSRO5_3256	COG3243	poly(R)-hydroxyalkanoic acid synthase
VCSRO5_3258	COG0183	Belongs to the thiolase family
VCSRO5_3260	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO5_3261	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO5_3265	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCSRO5_3267	COG1979	alcohol dehydrogenase
VCSRO5_3271	COG4191	Histidine kinase
VCSRO5_3273	COG2271	Major facilitator Superfamily
VCSRO5_3274	COG0469	pyruvate kinase activity
VCSRO5_3276	COG1879	ABC-type sugar transport system periplasmic component
VCSRO5_3277	COG1803	Methylglyoxal synthase
VCSRO5_3278	COG1335	isochorismatase
VCSRO5_3279	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VCSRO5_3282	COG0210	DNA helicase
VCSRO5_3283	COG1289	transmembrane transporter activity
VCSRO5_3289	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
VCSRO5_3290	COG4149	molybdate abc transporter
VCSRO5_3291	COG0725	ABC transporter, periplasmic molybdate-binding protein
VCSRO5_3292	COG1492	cobalamin metabolic process
VCSRO5_3299	COG0784	Response regulator, receiver
VCSRO5_3299	COG5002	protein histidine kinase activity
VCSRO5_3300	COG1879	ABC-type sugar transport system periplasmic component
VCSRO5_3302	COG2827	Endonuclease containing a URI domain
VCSRO5_3303	COG3132	Protein of unknown function, DUF480
VCSRO5_3305	COG2926	Belongs to the UPF0265 family
VCSRO5_3308	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
VCSRO5_3309	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VCSRO5_3310	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCSRO5_3311	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
VCSRO5_3312	COG0247	lactate metabolic process
VCSRO5_3313	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCSRO5_3314	COG3118	belongs to the thioredoxin family
VCSRO5_3320	COG0583	DNA-binding transcription factor activity
VCSRO5_3321	COG4160	amino acid transport
VCSRO5_3322	COG4215	(ABC) transporter
VCSRO5_3323	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO5_3324	COG1126	abc transporter atp-binding protein
VCSRO5_3326	COG2425	protein containing a von Willebrand factor type A (vWA) domain
VCSRO5_3328	COG0494	nUDIX hydrolase
VCSRO5_3329	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VCSRO5_3331	COG1309	transcriptional regulator
VCSRO5_3332	COG0513	Belongs to the DEAD box helicase family
VCSRO5_3333	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
VCSRO5_3335	COG0814	amino acid
VCSRO5_3336	COG0840	transmembrane signaling receptor activity
VCSRO5_3337	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VCSRO5_3338	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
VCSRO5_3340	COG1984	allophanate hydrolase subunit 2
VCSRO5_3343	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VCSRO5_3344	COG4181	ATPase activity
VCSRO5_3346	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCSRO5_3347	COG5001	Diguanylate cyclase
VCSRO5_3347	COG1716	ATPase activity
VCSRO5_3349	COG0484	heat shock protein binding
VCSRO5_3353	COG0546	phosphoglycolate phosphatase activity
VCSRO5_3356	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO5_3357	COG1368	sulfuric ester hydrolase activity
VCSRO5_3359	COG0513	Belongs to the DEAD box helicase family
VCSRO5_3362	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCSRO5_3364	COG3046	protein related to deoxyribodipyrimidine photolyase
VCSRO5_3365	COG3397	chitin binding
VCSRO5_3366	COG3227	Zinc metalloprotease (Elastase)
VCSRO5_3369	COG1166	arginine decarboxylase activity
VCSRO5_3371	COG2239	Acts as a magnesium transporter
VCSRO5_3372	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCSRO5_3373	COG0459	protein refolding
VCSRO5_3375	COG0527	aspartate kinase activity
VCSRO5_3376	COG0662	Cupin 2, conserved barrel domain protein
VCSRO5_3377	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VCSRO5_3378	COG0456	acetyltransferase
VCSRO5_3379	COG2154	pterin-4-alpha-carbinolamine dehydratase
VCSRO5_3380	COG3186	Phenylalanine-4-hydroxylase
VCSRO5_3381	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCSRO5_3384	COG2264	protein methyltransferase activity
VCSRO5_3389	COG1253	flavin adenine dinucleotide binding
VCSRO5_3390	COG1765	OsmC-like protein
VCSRO5_3395	COG0531	amino acid
VCSRO5_3398	COG3279	Response regulator of the LytR AlgR family
VCSRO5_3399	COG3275	phosphorelay sensor kinase activity
VCSRO5_3402	COG0577	efflux transmembrane transporter activity
VCSRO5_3402	COG1136	(ABC) transporter
VCSRO5_3403	COG1136	(ABC) transporter
VCSRO5_3405	COG4989	oxidoreductase activity
VCSRO5_3406	COG0366	Alpha amylase catalytic
VCSRO5_3407	COG2067	long-chain fatty acid transport protein
VCSRO5_3408	COG2267	carboxylic ester hydrolase activity
VCSRO5_3410	COG3227	Zinc metalloprotease (Elastase)
VCSRO5_3411	COG3047	cAMP biosynthetic process
VCSRO5_3414	COG1686	Belongs to the peptidase S11 family
VCSRO5_3415	COG0557	exoribonuclease II activity
VCSRO5_3416	COG1278	Cold shock
VCSRO5_3418	COG3048	D-serine ammonia-lyase activity
VCSRO5_3419	COG0583	DNA-binding transcription factor activity
VCSRO5_3432	COG1337	RAMP superfamily
VCSRO5_3458	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCSRO5_3459	COG0569	domain protein
VCSRO5_3460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCSRO5_3461	COG0745	RESPONSE REGULATOR receiver
VCSRO5_3462	COG2205	protein histidine kinase activity
VCSRO5_3465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VCSRO5_3466	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VCSRO5_3471	COG1802	Transcriptional regulator
VCSRO5_3471	COG4626	Terminase
VCSRO5_3478	COG0582	viral genome integration into host DNA
VCSRO5_3479	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
VCSRO5_3481	COG1063	alcohol dehydrogenase
VCSRO5_3483	COG2873	o-acetylhomoserine
VCSRO5_3485	COG0346	lactoylglutathione lyase activity
VCSRO5_3489	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
VCSRO5_3490	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO5_3491	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VCSRO5_3492	COG0363	glucosamine-6-phosphate deaminase activity
VCSRO5_3493	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VCSRO5_3498	COG1929	Belongs to the glycerate kinase type-1 family
VCSRO5_3500	COG0748	coenzyme F420 binding
VCSRO5_3501	COG3721	Heme iron utilization protein
VCSRO5_3503	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCSRO5_3504	COG0811	peptide transport
VCSRO5_3505	COG0848	biopolymer transport protein
VCSRO5_3506	COG4558	Periplasmic binding protein
VCSRO5_3507	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO5_3508	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VCSRO5_3515	COG0633	Ferredoxin
VCSRO5_3515	COG3217	Mosc domain protein beta barrel domain protein
VCSRO5_3515	COG0633	Ferredoxin
VCSRO5_3515	COG3217	Mosc domain protein beta barrel domain protein
VCSRO5_3516	COG0418	dihydroorotase activity
VCSRO5_3518	COG3152	Membrane
VCSRO5_3520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCSRO5_3521	COG2354	Protein conserved in bacteria
VCSRO5_3522	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO5_3523	COG1278	Cold shock
VCSRO5_3528	COG2199	diguanylate cyclase activity
VCSRO5_3529	COG1349	DNA-binding transcription factor activity
VCSRO5_3532	COG3833	ABC-type maltose transport systems, permease component
VCSRO5_3533	COG1175	transmembrane transport
VCSRO5_3535	COG3842	ATPase activity
VCSRO5_3536	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO5_3539	COG0393	Putative heavy-metal-binding
VCSRO5_3541	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO5_3542	COG0784	Response regulator, receiver
VCSRO5_3542	COG0835	chemotaxis
VCSRO5_3543	COG1846	Transcriptional regulator
VCSRO5_3544	COG3706	GGDEF domain
VCSRO5_3551	COG0583	DNA-binding transcription factor activity
VCSRO5_3552	COG5001	Diguanylate cyclase
VCSRO5_3554	COG1741	Belongs to the pirin family
VCSRO5_3555	COG3123	guanosine phosphorylase activity
VCSRO5_3557	COG2211	Major facilitator Superfamily
VCSRO5_3560	COG1067	ATP-dependent peptidase activity
VCSRO5_3562	COG4172	Belongs to the ABC transporter superfamily
VCSRO5_3566	COG0583	DNA-binding transcription factor activity
VCSRO5_3567	COG1620	l-lactate permease
VCSRO5_3570	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
VCSRO5_3572	COG0840	transmembrane signaling receptor activity
VCSRO5_3574	COG0513	Belongs to the DEAD box helicase family
VCSRO5_3575	COG0583	DNA-binding transcription factor activity
VCSRO5_3577	COG1902	pentaerythritol trinitrate reductase activity
VCSRO5_3579	COG1132	(ABC) transporter
VCSRO5_3581	COG1902	pentaerythritol trinitrate reductase activity
VCSRO5_3583	COG1280	lysine exporter protein (LysE YggA)
VCSRO5_3584	COG2207	Transcriptional regulator
VCSRO5_3588	COG1846	Transcriptional regulator
VCSRO5_3589	COG1764	response to oxidative stress
VCSRO5_3590	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCSRO5_3591	COG0697	spore germination
VCSRO5_3593	COG0700	Nucleoside recognition
VCSRO5_3594	COG3366	ferrous iron transmembrane transporter activity
VCSRO5_3595	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
VCSRO5_3597	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VCSRO5_3598	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
VCSRO5_3599	COG2259	Doxx family
VCSRO5_3604	COG0363	glucosamine-6-phosphate deaminase activity
VCSRO5_3607	COG4580	involved in the transport of maltose and maltodextrins
VCSRO5_3610	COG0840	transmembrane signaling receptor activity
VCSRO5_3613	COG0840	transmembrane signaling receptor activity
VCSRO5_3615	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO5_3616	COG1126	abc transporter atp-binding protein
VCSRO5_3618	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO5_3619	COG4597	amino acid ABC transporter
VCSRO5_3620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCSRO5_3621	COG2213	PTS system mannitol-specific
VCSRO5_3621	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO5_3622	COG0246	Mannitol dehydrogenase
VCSRO5_3623	COG3722	fumarate hydratase activity
VCSRO5_3624	COG0673	inositol 2-dehydrogenase activity
VCSRO5_3630	COG2910	NAD(P)H-binding
VCSRO5_3632	COG0840	transmembrane signaling receptor activity
VCSRO5_3633	COG4221	oxidoreductase activity
VCSRO5_3635	COG1901	pseudouridine methyltransferase
VCSRO5_3637	COG0531	amino acid
VCSRO5_3638	COG1982	Orn Lys Arg decarboxylase major
VCSRO5_3643	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCSRO5_3649	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VCSRO5_3657	COG0745	RESPONSE REGULATOR receiver
VCSRO5_3662	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCSRO5_3663	COG0840	transmembrane signaling receptor activity
VCSRO5_3664	COG0835	chemotaxis
VCSRO5_3665	COG0835	chemotaxis
VCSRO5_3666	COG2198	Histidine kinase
VCSRO5_3666	COG0643	Histidine kinase
VCSRO5_3669	COG0747	negative chemotaxis
VCSRO5_3670	COG0601	transmembrane transport
VCSRO5_3671	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO5_3673	COG2194	sulfuric ester hydrolase activity
VCSRO5_3674	COG0642	Histidine kinase
VCSRO5_3681	COG1444	tRNA N-acetyltransferase activity
VCSRO5_3682	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine