locus-tag	class	description
VCSRO45_0001	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCSRO45_0013	COG1104	cysteine desulfurase activity
VCSRO45_0018	COG4974	Belongs to the 'phage' integrase family
VCSRO45_0027	COG0464	growth
VCSRO45_0030	COG1074	ATP-dependent DNA helicase activity
VCSRO45_0049	COG4974	Belongs to the 'phage' integrase family
VCSRO45_0050	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
VCSRO45_0051	COG3385	transposase activity
VCSRO45_0052	COG0706	membrane insertase activity
VCSRO45_0053	COG0594	ribonuclease P activity
VCSRO45_0054	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VCSRO45_0055	COG1126	abc transporter atp-binding protein
VCSRO45_0058	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VCSRO45_0059	COG0592	DNA-directed DNA polymerase activity
VCSRO45_0060	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VCSRO45_0061	COG0187	DNA topoisomerase II activity
VCSRO45_0064	COG0071	Belongs to the small heat shock protein (HSP20) family
VCSRO45_0065	COG3977	Valine--pyruvate aminotransferase
VCSRO45_0066	COG0751	glycine-tRNA ligase activity
VCSRO45_0067	COG0752	glycyl-tRNA synthetase alpha subunit
VCSRO45_0068	COG2119	membrane
VCSRO45_0070	COG0425	Belongs to the sulfur carrier protein TusA family
VCSRO45_0072	COG0604	alcohol dehydrogenase
VCSRO45_0074	COG0129	dihydroxy-acid dehydratase activity
VCSRO45_0075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCSRO45_0078	COG0606	chelatase, subunit chli
VCSRO45_0079	COG0204	Acyl-transferase
VCSRO45_0080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCSRO45_0081	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VCSRO45_0083	COG3084	Protein conserved in bacteria
VCSRO45_0084	COG4326	sporulation control protein
VCSRO45_0085	COG1272	protein, Hemolysin III
VCSRO45_0087	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCSRO45_0088	COG0569	domain protein
VCSRO45_0089	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCSRO45_0089	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VCSRO45_0091	COG0242	peptide deformylase activity
VCSRO45_0092	COG1652	LysM domain
VCSRO45_0093	COG0758	DNA mediated transformation
VCSRO45_0094	COG2922	Belongs to the Smg family
VCSRO45_0095	COG0551	DNA topoisomerase type I activity
VCSRO45_0096	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VCSRO45_0097	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VCSRO45_0098	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO45_0099	COG0408	coproporphyrinogen oxidase activity
VCSRO45_0100	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VCSRO45_0102	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VCSRO45_0109	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VCSRO45_0110	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VCSRO45_0112	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCSRO45_0113	COG2104	thiamine diphosphate biosynthetic process
VCSRO45_0114	COG2022	thiamine diphosphate biosynthetic process
VCSRO45_0115	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCSRO45_0116	COG0006	proline dipeptidase activity
VCSRO45_0116	COG0006	proline dipeptidase activity
VCSRO45_0120	COG1522	sequence-specific DNA binding
VCSRO45_0121	COG5002	protein histidine kinase activity
VCSRO45_0121	COG5001	Diguanylate cyclase
VCSRO45_0125	COG0589	response to stress
VCSRO45_0126	COG1528	Iron-storage protein
VCSRO45_0128	COG2081	HI0933 family
VCSRO45_0131	COG1322	Protein conserved in bacteria
VCSRO45_0132	COG2226	methyltransferase
VCSRO45_0135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO45_0136	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO45_0137	COG0805	protein transport
VCSRO45_0138	COG1858	cytochrome C peroxidase
VCSRO45_0139	COG0534	Mate efflux family protein
VCSRO45_0141	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VCSRO45_0142	COG2937	Belongs to the GPAT DAPAT family
VCSRO45_0143	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VCSRO45_0144	COG3161	chorismate lyase activity
VCSRO45_0145	COG1580	Controls the rotational direction of flagella during chemotaxis
VCSRO45_0146	COG0840	transmembrane signaling receptor activity
VCSRO45_0148	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO45_0149	COG0084	hydrolase, TatD family'
VCSRO45_0152	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO45_0152	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO45_0156	COG3078	GTPase activator activity
VCSRO45_0159	COG3071	HemY protein
VCSRO45_0160	COG2959	enzyme of heme biosynthesis
VCSRO45_0161	COG1587	Uroporphyrinogen-III synthase
VCSRO45_0162	COG0181	hydroxymethylbilane synthase activity
VCSRO45_0164	COG1965	Belongs to the frataxin family
VCSRO45_0165	COG0019	diaminopimelate decarboxylase activity
VCSRO45_0166	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VCSRO45_0168	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VCSRO45_0169	COG1011	Hydrolase
VCSRO45_0170	COG3287	FIST C domain
VCSRO45_0170	COG2200	EAL domain
VCSRO45_0170	COG2199	diguanylate cyclase activity
VCSRO45_0174	COG0561	phosphatase activity
VCSRO45_0175	COG2267	carboxylic ester hydrolase activity
VCSRO45_0176	COG1280	lysine exporter protein (LysE YggA)
VCSRO45_0177	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCSRO45_0178	COG0783	Belongs to the Dps family
VCSRO45_0184	COG0742	ribosomal rna small subunit methyltransferase
VCSRO45_0185	COG0552	protein localization to endoplasmic reticulum
VCSRO45_0186	COG2884	Cell division ATP-binding protein ftsE
VCSRO45_0187	COG2177	Part of the ABC transporter FtsEX involved in
VCSRO45_0188	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCSRO45_0189	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO45_0192	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCSRO45_0193	COG4206	TonB-dependent receptor
VCSRO45_0194	COG1404	Belongs to the peptidase S8 family
VCSRO45_0195	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
VCSRO45_0209	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VCSRO45_0210	COG3300	MHYT domain
VCSRO45_0210	COG5001	Diguanylate cyclase
VCSRO45_0212	COG3852	Histidine kinase
VCSRO45_0214	COG0174	glutamine synthetase
VCSRO45_0216	COG1217	gtp-binding protein TYPA
VCSRO45_0218	COG1295	ribonuclease BN
VCSRO45_0219	COG1490	D-aminoacyl-tRNA deacylase activity
VCSRO45_0220	COG0456	acetyltransferase
VCSRO45_0222	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
VCSRO45_0223	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VCSRO45_0224	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VCSRO45_0225	COG3031	protein transport across the cell outer membrane
VCSRO45_0227	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO45_0228	COG1459	type II secretion system
VCSRO45_0229	COG2165	general secretion pathway protein
VCSRO45_0230	COG2165	general secretion pathway protein
VCSRO45_0231	COG2165	general secretion pathway protein
VCSRO45_0232	COG4795	General secretion pathway protein
VCSRO45_0233	COG3156	type II secretion system protein K
VCSRO45_0234	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCSRO45_0235	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCSRO45_0237	COG1218	3'(2'),5'-bisphosphate nucleotidase
VCSRO45_0238	COG0494	nUDIX hydrolase
VCSRO45_0240	COG1040	competence protein
VCSRO45_0241	COG0596	Alpha beta hydrolase
VCSRO45_0243	COG2183	response to ionizing radiation
VCSRO45_0244	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO45_0247	COG1129	ABC transporter
VCSRO45_0248	COG1172	Belongs to the binding-protein-dependent transport system permease family
VCSRO45_0249	COG1472	Belongs to the glycosyl hydrolase 3 family
VCSRO45_0253	COG2233	PERMEase
VCSRO45_0254	COG3547	Transposase (IS116 IS110 IS902 family)
VCSRO45_0255	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VCSRO45_0256	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCSRO45_0257	COG1758	RNA polymerase activity
VCSRO45_0258	COG0194	GDP metabolic process
VCSRO45_0259	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VCSRO45_0260	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCSRO45_0264	COG4232	protein-disulfide reductase activity
VCSRO45_0266	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCSRO45_0268	COG1027	Aspartate ammonia-lyase
VCSRO45_0269	COG3706	GGDEF domain
VCSRO45_0270	COG3030	protein affecting phage T7 exclusion by the F plasmid
VCSRO45_0271	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VCSRO45_0273	COG2205	protein histidine kinase activity
VCSRO45_0274	COG0745	RESPONSE REGULATOR receiver
VCSRO45_0276	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VCSRO45_0277	COG0205	6-phosphofructokinase activity
VCSRO45_0278	COG1494	fructose-1,6-bisphosphatase
VCSRO45_0279	COG3074	FtsZ-dependent cytokinesis
VCSRO45_0280	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VCSRO45_0281	COG0527	aspartate kinase activity
VCSRO45_0281	COG0460	homoserine dehydrogenase
VCSRO45_0282	COG0626	cystathionine gamma-synthase activity
VCSRO45_0283	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
VCSRO45_0284	COG0281	malic enzyme
VCSRO45_0285	COG0254	rRNA binding
VCSRO45_0286	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VCSRO45_0287	COG1609	Transcriptional regulator
VCSRO45_0288	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCSRO45_0289	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VCSRO45_0290	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VCSRO45_0291	COG1575	Belongs to the MenA family. Type 1 subfamily
VCSRO45_0292	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCSRO45_0293	COG0534	Mate efflux family protein
VCSRO45_0294	COG0149	triose-phosphate isomerase activity
VCSRO45_0299	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCSRO45_0300	COG0459	protein refolding
VCSRO45_0302	COG1509	lysine 2,3-aminomutase activity
VCSRO45_0303	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCSRO45_0305	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VCSRO45_0306	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VCSRO45_0307	COG1053	succinate dehydrogenase
VCSRO45_0308	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VCSRO45_0309	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO45_0310	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VCSRO45_0311	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VCSRO45_0312	COG1045	serine acetyltransferase
VCSRO45_0314	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VCSRO45_0315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VCSRO45_0316	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VCSRO45_0317	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCSRO45_0318	COG0137	argininosuccinate synthase activity
VCSRO45_0319	COG0165	Argininosuccinate lyase
VCSRO45_0321	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO45_0322	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCSRO45_0322	COG0678	peroxiredoxin activity
VCSRO45_0324	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VCSRO45_0330	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VCSRO45_0331	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VCSRO45_0333	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VCSRO45_0334	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VCSRO45_0335	COG0546	phosphoglycolate phosphatase activity
VCSRO45_0336	COG0180	Tryptophanyl-tRNA synthetase
VCSRO45_0339	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCSRO45_0341	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VCSRO45_0343	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO45_0346	COG2801	Transposase and inactivated derivatives
VCSRO45_0348	COG3954	Phosphoribulokinase
VCSRO45_0350	COG0429	hydrolase of the alpha beta-hydrolase fold
VCSRO45_0352	COG0488	(ABC) transporter
VCSRO45_0353	COG2249	NAD(P)H dehydrogenase (quinone) activity
VCSRO45_0356	COG1047	Peptidyl-prolyl cis-trans
VCSRO45_0358	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VCSRO45_0359	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VCSRO45_0360	COG3083	sulfuric ester hydrolase activity
VCSRO45_0361	COG0557	exoribonuclease II activity
VCSRO45_0362	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCSRO45_0363	COG0051	transcription antitermination factor activity, RNA binding
VCSRO45_0364	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VCSRO45_0365	COG0088	Forms part of the polypeptide exit tunnel
VCSRO45_0366	COG0089	rRNA binding
VCSRO45_0367	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VCSRO45_0368	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VCSRO45_0369	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VCSRO45_0370	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VCSRO45_0371	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VCSRO45_0372	COG0255	Belongs to the universal ribosomal protein uL29 family
VCSRO45_0373	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VCSRO45_0374	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VCSRO45_0375	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VCSRO45_0376	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VCSRO45_0377	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VCSRO45_0378	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VCSRO45_0380	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VCSRO45_0381	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VCSRO45_0382	COG1841	ribosomal large subunit assembly
VCSRO45_0384	COG0201	protein transport
VCSRO45_0385	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCSRO45_0386	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VCSRO45_0387	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VCSRO45_0388	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VCSRO45_0389	COG0202	RNA polymerase activity
VCSRO45_0390	COG0203	ribosomal protein L17
VCSRO45_0392	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO45_0393	COG3266	domain, Protein
VCSRO45_0393	COG3061	Opacity-associated protein A
VCSRO45_0394	COG0697	spore germination
VCSRO45_0395	COG2153	protein acetylation
VCSRO45_0396	COG0513	Belongs to the DEAD box helicase family
VCSRO45_0398	COG0737	Belongs to the 5'-nucleotidase family
VCSRO45_0399	COG1648	precorrin-2 dehydrogenase activity
VCSRO45_0399	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VCSRO45_0400	COG0175	sulfate reduction
VCSRO45_0401	COG2895	sulfate adenylyltransferase (ATP) activity
VCSRO45_0402	COG0529	Catalyzes the synthesis of activated sulfate
VCSRO45_0406	COG0577	efflux transmembrane transporter activity
VCSRO45_0406	COG1136	(ABC) transporter
VCSRO45_0409	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VCSRO45_0410	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO45_0411	COG0729	surface antigen
VCSRO45_0412	COG2911	Protein conserved in bacteria
VCSRO45_0413	COG2105	PFAM AIG2 family protein
VCSRO45_0414	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VCSRO45_0416	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCSRO45_0417	COG0163	prenyltransferase activity
VCSRO45_0419	COG1178	ABC-type Fe3 transport system permease component
VCSRO45_0420	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VCSRO45_0421	COG3028	Belongs to the UPF0307 family
VCSRO45_0422	COG0312	modulator of DNA gyrase
VCSRO45_0423	COG2239	Acts as a magnesium transporter
VCSRO45_0424	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO45_0425	COG1660	Displays ATPase and GTPase activities
VCSRO45_0426	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO45_0427	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCSRO45_0429	COG1137	ATPase activity
VCSRO45_0430	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VCSRO45_0433	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VCSRO45_0433	COG0517	IMP dehydrogenase activity
VCSRO45_0435	COG1127	ABC transporter
VCSRO45_0436	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VCSRO45_0437	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCSRO45_0438	COG2854	intermembrane phospholipid transfer
VCSRO45_0440	COG5007	Belongs to the BolA IbaG family
VCSRO45_0441	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VCSRO45_0443	COG0251	oxidation-reduction process
VCSRO45_0445	COG0540	Belongs to the ATCase OTCase family
VCSRO45_0447	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VCSRO45_0448	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VCSRO45_0449	COG0564	pseudouridine synthase activity
VCSRO45_0450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCSRO45_0451	COG0525	valine-tRNA ligase activity
VCSRO45_0452	COG2927	DNA polymerase III (CHI subunit)
VCSRO45_0453	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCSRO45_0454	COG0795	lipopolysaccharide-transporting ATPase activity
VCSRO45_0455	COG0795	lipopolysaccharide-transporting ATPase activity
VCSRO45_0458	COG3437	response regulator, receiver
VCSRO45_0467	COG0066	3-isopropylmalate dehydratase activity
VCSRO45_0468	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
VCSRO45_0469	COG0473	3-isopropylmalate dehydrogenase activity
VCSRO45_0474	COG0583	DNA-binding transcription factor activity
VCSRO45_0475	COG1022	Amp-dependent synthetase and ligase
VCSRO45_0476	COG0028	Belongs to the TPP enzyme family
VCSRO45_0477	COG0440	acetolactate synthase activity
VCSRO45_0478	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO45_0479	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VCSRO45_0480	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VCSRO45_0481	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VCSRO45_0482	COG3079	Belongs to the UPF0149 family
VCSRO45_0483	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO45_0484	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO45_0487	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VCSRO45_0489	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VCSRO45_0490	COG1595	DNA-templated transcription, initiation
VCSRO45_0493	COG3086	response to oxidative stress
VCSRO45_0494	COG0481	GTPase activity
VCSRO45_0496	COG0571	ribonuclease III activity
VCSRO45_0497	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VCSRO45_0498	COG1381	Involved in DNA repair and RecF pathway recombination
VCSRO45_0499	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VCSRO45_0504	COG5001	Diguanylate cyclase
VCSRO45_0507	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCSRO45_0508	COG3956	TIGRFAM MazG family protein
VCSRO45_0509	COG0504	CTP synthase activity
VCSRO45_0510	COG0148	phosphopyruvate hydratase activity
VCSRO45_0511	COG0617	tRNA 3'-terminal CCA addition
VCSRO45_0512	COG3267	Type II secretory pathway component ExeA
VCSRO45_0512	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO45_0514	COG4991	sh3 domain protein
VCSRO45_0515	COG0306	phosphate transporter
VCSRO45_0516	COG1392	Phosphate transport regulator
VCSRO45_0517	COG3025	triphosphatase activity
VCSRO45_0519	COG0840	transmembrane signaling receptor activity
VCSRO45_0520	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VCSRO45_0522	COG1538	Outer membrane efflux protein
VCSRO45_0523	COG0494	nUDIX hydrolase
VCSRO45_0524	COG3151	Protein conserved in bacteria
VCSRO45_0526	COG3150	esterase
VCSRO45_0527	COG0187	DNA topoisomerase II activity
VCSRO45_0528	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VCSRO45_0530	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VCSRO45_0531	COG0237	dephospho-CoA kinase activity
VCSRO45_0533	COG1459	type II secretion system
VCSRO45_0534	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO45_0535	COG4969	Belongs to the N-Me-Phe pilin family
VCSRO45_0538	COG0716	FMN binding
VCSRO45_0539	COG4974	Belongs to the 'phage' integrase family
VCSRO45_0540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCSRO45_0541	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VCSRO45_0542	COG0737	Belongs to the 5'-nucleotidase family
VCSRO45_0543	COG2186	Transcriptional regulator
VCSRO45_0544	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VCSRO45_0545	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCSRO45_0546	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO45_0548	COG3116	cell division
VCSRO45_0549	COG0768	penicillin binding
VCSRO45_0550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VCSRO45_0551	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VCSRO45_0553	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VCSRO45_0554	COG0772	Belongs to the SEDS family
VCSRO45_0556	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCSRO45_0557	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VCSRO45_0558	COG0849	cell division
VCSRO45_0559	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VCSRO45_0560	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VCSRO45_0562	COG0653	protein targeting
VCSRO45_0563	COG0494	nUDIX hydrolase
VCSRO45_0564	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
VCSRO45_0565	COG0505	Belongs to the CarA family
VCSRO45_0566	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VCSRO45_0569	COG0730	response to heat
VCSRO45_0570	COG0583	DNA-binding transcription factor activity
VCSRO45_0571	COG2860	membrane
VCSRO45_0572	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VCSRO45_0574	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VCSRO45_0576	COG0493	'glutamate synthase
VCSRO45_0577	COG0067	glutamate synthase
VCSRO45_0577	COG0069	glutamate synthase activity
VCSRO45_0577	COG0070	glutamate synthase
VCSRO45_0579	COG0067	glutamate synthase
VCSRO45_0579	COG0069	glutamate synthase activity
VCSRO45_0579	COG0070	glutamate synthase
VCSRO45_0580	COG1242	4 iron, 4 sulfur cluster binding
VCSRO45_0581	COG5001	Diguanylate cyclase
VCSRO45_0581	COG4251	negative regulation of phosphorylation
VCSRO45_0581	COG3706	GGDEF domain
VCSRO45_0581	COG2203	Gaf domain
VCSRO45_0582	COG5002	protein histidine kinase activity
VCSRO45_0582	COG0784	Response regulator, receiver
VCSRO45_0582	COG2198	Histidine kinase
VCSRO45_0583	COG0745	RESPONSE REGULATOR receiver
VCSRO45_0585	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCSRO45_0588	COG0083	homoserine kinase activity
VCSRO45_0589	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VCSRO45_0590	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VCSRO45_0591	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VCSRO45_0592	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VCSRO45_0595	COG1115	amino acid carrier protein
VCSRO45_0596	COG3022	response to hydroperoxide
VCSRO45_0598	COG0084	hydrolase, TatD family'
VCSRO45_0599	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO45_0600	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VCSRO45_0601	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO45_0602	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VCSRO45_0603	COG0813	purine-nucleoside phosphorylase activity
VCSRO45_0604	COG3385	transposase activity
VCSRO45_0606	COG0560	Phosphoserine phosphatase
VCSRO45_0608	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VCSRO45_0609	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCSRO45_0610	COG1022	Amp-dependent synthetase and ligase
VCSRO45_0613	COG3250	beta-galactosidase activity
VCSRO45_0614	COG1609	Transcriptional regulator
VCSRO45_0615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO45_0618	COG0189	ligase activity
VCSRO45_0618	COG0569	domain protein
VCSRO45_0622	COG2171	N-acyltransferase activity
VCSRO45_0623	COG3141	response to X-ray
VCSRO45_0626	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VCSRO45_0627	COG1074	ATP-dependent DNA helicase activity
VCSRO45_0628	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VCSRO45_0630	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VCSRO45_0630	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCSRO45_0632	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VCSRO45_0633	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VCSRO45_0634	COG2166	iron-sulfur cluster assembly
VCSRO45_0635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCSRO45_0636	COG0693	protein deglycase activity
VCSRO45_0637	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VCSRO45_0638	COG3248	Nucleoside-binding outer membrane protein
VCSRO45_0640	COG1595	DNA-templated transcription, initiation
VCSRO45_0642	COG2211	Major facilitator Superfamily
VCSRO45_0643	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCSRO45_0645	COG2813	Specifically methylates the guanine in position
VCSRO45_0646	COG0271	Belongs to the BolA IbaG family
VCSRO45_0647	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO45_0648	COG1805	sodium ion transport
VCSRO45_0649	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO45_0650	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO45_0651	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO45_0652	COG2871	sodium ion transport
VCSRO45_0653	COG1477	protein flavinylation
VCSRO45_0657	COG3706	GGDEF domain
VCSRO45_0658	COG0733	neurotransmitter:sodium symporter activity
VCSRO45_0660	COG0189	ligase activity
VCSRO45_0661	COG0189	ligase activity
VCSRO45_0661	COG4067	protein conserved in archaea
VCSRO45_0662	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO45_0663	COG2252	PERMEase
VCSRO45_0664	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VCSRO45_0665	COG1073	alpha beta
VCSRO45_0667	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VCSRO45_0668	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VCSRO45_0669	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VCSRO45_0670	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO45_0670	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO45_0673	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VCSRO45_0674	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCSRO45_0675	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VCSRO45_0676	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VCSRO45_0678	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VCSRO45_0679	COG0024	Methionine aminopeptidase
VCSRO45_0680	COG0052	Belongs to the universal ribosomal protein uS2 family
VCSRO45_0681	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VCSRO45_0682	COG0528	UMP kinase activity
VCSRO45_0683	COG0233	cytoplasmic translational termination
VCSRO45_0684	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VCSRO45_0685	COG0575	Belongs to the CDS family
VCSRO45_0686	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VCSRO45_0687	COG0750	zinc metalloprotease
VCSRO45_0689	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VCSRO45_0690	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO45_0691	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCSRO45_0692	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO45_0693	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO45_0694	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
VCSRO45_0695	COG0587	DNA-directed DNA polymerase activity
VCSRO45_0696	COG0825	malonyl-CoA metabolic process
VCSRO45_0697	COG0037	tRNA processing
VCSRO45_0699	COG3479	Phenolic acid decarboxylase
VCSRO45_0700	COG0347	Belongs to the P(II) protein family
VCSRO45_0701	COG3021	interspecies interaction between organisms
VCSRO45_0702	COG1388	LysM domain
VCSRO45_0702	COG0741	lytic transglycosylase activity
VCSRO45_0703	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCSRO45_0704	COG2226	methyltransferase
VCSRO45_0705	COG0328	RNA-DNA hybrid ribonuclease activity
VCSRO45_0708	COG1960	acyl-CoA dehydrogenase activity
VCSRO45_0709	COG1960	acyl-CoA dehydrogenase activity
VCSRO45_0710	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCSRO45_0711	COG0121	glutamine amidotransferase
VCSRO45_0712	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VCSRO45_0713	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VCSRO45_0714	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VCSRO45_0716	COG1187	pseudouridine synthase activity
VCSRO45_0717	COG2840	Smr protein MutS2
VCSRO45_0723	COG2217	Heavy metal translocating P-type atpase
VCSRO45_0723	COG2608	mercury ion transmembrane transporter activity
VCSRO45_0724	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCSRO45_0727	COG4774	siderophore transport
VCSRO45_0727	COG1629	transport
VCSRO45_0728	COG2375	cellular response to nickel ion
VCSRO45_0729	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCSRO45_0729	COG2226	methyltransferase
VCSRO45_0729	COG3433	isochorismatase activity
VCSRO45_0736	COG0784	Response regulator, receiver
VCSRO45_0736	COG0835	chemotaxis
VCSRO45_0737	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCSRO45_0738	COG1815	bacterial-type flagellum-dependent cell motility
VCSRO45_0741	COG1749	Flagellar hook protein flgE
VCSRO45_0742	COG4787	bacterial-type flagellum-dependent cell motility
VCSRO45_0744	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VCSRO45_0745	COG1706	bacterial-type flagellum-dependent cell motility
VCSRO45_0746	COG1705	Flagellar rod assembly protein muramidase FlgJ
VCSRO45_0746	COG3951	Flagellar rod assembly protein muramidase FlgJ
VCSRO45_0749	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO45_0750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO45_0767	COG0012	GTP binding
VCSRO45_0768	COG0193	aminoacyl-tRNA hydrolase activity
VCSRO45_0769	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VCSRO45_0770	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VCSRO45_0771	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VCSRO45_0772	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VCSRO45_0773	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VCSRO45_0774	COG2890	protein-(glutamine-N5) methyltransferase activity
VCSRO45_0776	COG2912	Transglutaminase-like superfamily
VCSRO45_0777	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VCSRO45_0778	COG0737	Belongs to the 5'-nucleotidase family
VCSRO45_0779	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VCSRO45_0780	COG2233	PERMEase
VCSRO45_0784	COG1393	Belongs to the ArsC family
VCSRO45_0785	COG4783	chaperone-mediated protein folding
VCSRO45_0789	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VCSRO45_0792	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VCSRO45_0794	COG1876	peptidase activity
VCSRO45_0796	COG1393	Belongs to the ArsC family
VCSRO45_0800	COG2837	iron assimilation
VCSRO45_0801	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO45_0802	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO45_0803	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO45_0804	COG1334	flagellar protein FlaG
VCSRO45_0805	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VCSRO45_0807	COG1516	flagellar protein fliS
VCSRO45_0812	COG1677	Flagellar hook-basal body complex protein FliE
VCSRO45_0814	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VCSRO45_0819	COG1580	Controls the rotational direction of flagella during chemotaxis
VCSRO45_0824	COG1987	bacterial-type flagellum assembly
VCSRO45_0825	COG1684	flagellar biosynthetic protein fliR
VCSRO45_0827	COG2840	Smr protein MutS2
VCSRO45_0828	COG2890	protein-(glutamine-N5) methyltransferase activity
VCSRO45_0829	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VCSRO45_0830	COG2860	membrane
VCSRO45_0831	COG3101	peptidyl-lysine hydroxylation
VCSRO45_0833	COG0431	NADPH-dependent FMN reductase
VCSRO45_0834	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VCSRO45_0834	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VCSRO45_0835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCSRO45_0836	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO45_0837	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCSRO45_0838	COG0735	belongs to the Fur family
VCSRO45_0840	COG0583	DNA-binding transcription factor activity
VCSRO45_0842	COG1346	cytolysis
VCSRO45_0845	COG0596	Alpha beta hydrolase
VCSRO45_0846	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VCSRO45_0847	COG0033	Phosphoglucomutase
VCSRO45_0849	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VCSRO45_0850	COG0372	Belongs to the citrate synthase family
VCSRO45_0851	COG2009	succinate dehydrogenase
VCSRO45_0852	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VCSRO45_0853	COG1053	succinate dehydrogenase
VCSRO45_0855	COG0567	Dehydrogenase, E1 component
VCSRO45_0856	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCSRO45_0857	COG0045	succinate-CoA ligase (ADP-forming) activity
VCSRO45_0859	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VCSRO45_0860	COG1121	(ABC) transporter
VCSRO45_0861	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VCSRO45_0862	COG4977	sequence-specific DNA binding
VCSRO45_0863	COG1918	ferrous iron import across plasma membrane
VCSRO45_0867	COG0018	arginyl-trna synthetase
VCSRO45_0869	COG1025	Belongs to the peptidase M16 family
VCSRO45_0870	COG2062	phosphohistidine phosphatase, SixA
VCSRO45_0876	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VCSRO45_0877	COG0784	Response regulator, receiver
VCSRO45_0877	COG2198	Histidine kinase
VCSRO45_0877	COG0643	Histidine kinase
VCSRO45_0878	COG2201	protein-glutamate methylesterase activity
VCSRO45_0879	COG1192	Involved in chromosome partitioning
VCSRO45_0881	COG0835	chemotaxis
VCSRO45_0883	COG4133	protoheme IX ABC transporter activity
VCSRO45_0884	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCSRO45_0885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCSRO45_0887	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VCSRO45_0888	COG1138	Cytochrome C-type biogenesis protein
VCSRO45_0889	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VCSRO45_0890	COG3088	subunit of a heme lyase
VCSRO45_0890	COG4235	cytochrome complex assembly
VCSRO45_0892	COG2853	Lipoprotein
VCSRO45_0896	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VCSRO45_0897	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCSRO45_0898	COG0123	including yeast histone deacetylase and acetoin utilization protein
VCSRO45_0901	COG3083	sulfuric ester hydrolase activity
VCSRO45_0902	COG3082	Protein of unknown function (DUF1414)
VCSRO45_0903	COG3081	Nucleoid-associated protein
VCSRO45_0905	COG1757	Na H antiporter
VCSRO45_0906	COG1757	Na H antiporter
VCSRO45_0907	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCSRO45_0908	COG2095	MarC family integral membrane protein
VCSRO45_0909	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO45_0909	COG1454	alcohol dehydrogenase
VCSRO45_0911	COG3385	transposase activity
VCSRO45_0913	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO45_0914	COG1530	ribonuclease E activity
VCSRO45_0915	COG0564	pseudouridine synthase activity
VCSRO45_0916	COG0424	maF-like protein
VCSRO45_0917	COG1399	metal-binding, possibly nucleic acid-binding protein
VCSRO45_0918	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VCSRO45_0919	COG0416	fatty acid biosynthetic process
VCSRO45_0920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCSRO45_0922	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO45_0923	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VCSRO45_0924	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCSRO45_0925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCSRO45_0926	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VCSRO45_0927	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VCSRO45_0929	COG0084	hydrolase, TatD family'
VCSRO45_0930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO45_0930	COG1263	PTS System
VCSRO45_0932	COG0733	neurotransmitter:sodium symporter activity
VCSRO45_0935	COG4667	esterase of the alpha-beta hydrolase superfamily
VCSRO45_0937	COG1940	carbohydrate kinase activity
VCSRO45_0938	COG0835	chemotaxis
VCSRO45_0938	COG0784	Response regulator, receiver
VCSRO45_0941	COG2226	methyltransferase
VCSRO45_0943	COG0676	glucose-6-phosphate 1-epimerase activity
VCSRO45_0944	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO45_0945	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO45_0947	COG3139	Protein of unknown function (DUF1315)
VCSRO45_0948	COG0252	asparaginase activity
VCSRO45_0949	COG0616	signal peptide processing
VCSRO45_0950	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCSRO45_0950	COG1902	pentaerythritol trinitrate reductase activity
VCSRO45_0951	COG0788	formyltetrahydrofolate deformylase activity
VCSRO45_0953	COG1199	ATP-dependent helicase activity
VCSRO45_0954	COG1214	PFAM Peptidase M22, glycoprotease
VCSRO45_0957	COG0596	Alpha beta hydrolase
VCSRO45_0958	COG0318	PFAM AMP-dependent synthetase and ligase
VCSRO45_0959	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VCSRO45_0960	COG0705	Rhomboid family
VCSRO45_0962	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VCSRO45_0963	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VCSRO45_0964	COG0436	Aminotransferase
VCSRO45_0965	COG1169	isochorismate synthase
VCSRO45_0966	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VCSRO45_0967	COG0596	Alpha beta hydrolase
VCSRO45_0971	COG3135	benzoate transporter
VCSRO45_0972	COG1396	sequence-specific DNA binding
VCSRO45_0973	COG0840	transmembrane signaling receptor activity
VCSRO45_0979	COG3015	lipoprotein NlpE involved in copper resistance
VCSRO45_0980	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VCSRO45_0981	COG2894	cell division
VCSRO45_0982	COG0850	regulation of cytokinetic process
VCSRO45_0983	COG3100	YcgL domain-containing protein
VCSRO45_0984	COG2951	lytic endotransglycosylase activity
VCSRO45_0986	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO45_0987	COG3005	denitrification pathway
VCSRO45_0988	COG0243	molybdopterin cofactor binding
VCSRO45_0992	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO45_0994	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VCSRO45_1001	COG4589	Belongs to the CDS family
VCSRO45_1003	COG5001	Diguanylate cyclase
VCSRO45_1003	COG3300	MHYT domain
VCSRO45_1006	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VCSRO45_1007	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCSRO45_1008	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCSRO45_1009	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCSRO45_1010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCSRO45_1012	COG4191	Histidine kinase
VCSRO45_1013	COG0544	peptidyl-prolyl cis-trans isomerase activity
VCSRO45_1015	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VCSRO45_1016	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VCSRO45_1017	COG0776	regulation of translation
VCSRO45_1018	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO45_1019	COG1555	photosystem II stabilization
VCSRO45_1020	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VCSRO45_1021	COG0539	negative regulation of cytoplasmic translation
VCSRO45_1022	COG0776	regulation of translation
VCSRO45_1023	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VCSRO45_1024	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VCSRO45_1026	COG0601	transmembrane transport
VCSRO45_1027	COG4239	(ABC) transporter, permease
VCSRO45_1028	COG0747	negative chemotaxis
VCSRO45_1029	COG0444	Belongs to the ABC transporter superfamily
VCSRO45_1030	COG4608	Belongs to the ABC transporter superfamily
VCSRO45_1035	COG0583	DNA-binding transcription factor activity
VCSRO45_1037	COG0686	Belongs to the AlaDH PNT family
VCSRO45_1039	COG1674	ftsk spoiiie
VCSRO45_1040	COG3385	transposase activity
VCSRO45_1041	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VCSRO45_1042	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCSRO45_1043	COG2186	Transcriptional regulator
VCSRO45_1046	COG0537	adenosine 5'-monophosphoramidase activity
VCSRO45_1051	COG3150	esterase
VCSRO45_1052	COG1252	NADH dehydrogenase
VCSRO45_1056	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VCSRO45_1058	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO45_1059	COG1136	(ABC) transporter
VCSRO45_1060	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO45_1062	COG2333	competence protein COMEC
VCSRO45_1062	COG0658	competence protein
VCSRO45_1063	COG1132	(ABC) transporter
VCSRO45_1064	COG1663	tetraacyldisaccharide 4'-kinase activity
VCSRO45_1065	COG2835	tetraacyldisaccharide 4'-kinase activity
VCSRO45_1066	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VCSRO45_1067	COG2719	SpoVR family
VCSRO45_1068	COG2718	Belongs to the UPF0229 family
VCSRO45_1069	COG2766	serine protein kinase
VCSRO45_1070	COG3385	transposase activity
VCSRO45_1071	COG3013	Belongs to the UPF0304 family
VCSRO45_1073	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VCSRO45_1074	COG0840	transmembrane signaling receptor activity
VCSRO45_1076	COG1882	Formate acetyltransferase
VCSRO45_1083	COG4160	amino acid transport
VCSRO45_1084	COG0708	Exodeoxyribonuclease III
VCSRO45_1085	COG0840	transmembrane signaling receptor activity
VCSRO45_1087	COG3923	Primosomal replication protein n
VCSRO45_1088	COG0730	response to heat
VCSRO45_1089	COG1199	ATP-dependent helicase activity
VCSRO45_1091	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCSRO45_1092	COG3012	SEC-C Motif Domain Protein
VCSRO45_1093	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCSRO45_1094	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO45_1095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCSRO45_1096	COG0215	cysteine-tRNA ligase activity
VCSRO45_1097	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VCSRO45_1098	COG0632	four-way junction helicase activity
VCSRO45_1101	COG1271	oxidase subunit
VCSRO45_1102	COG1294	oxidase, subunit
VCSRO45_1103	COG4890	Cyd operon protein YbgT
VCSRO45_1104	COG0824	Thioesterase
VCSRO45_1105	COG0811	peptide transport
VCSRO45_1108	COG0823	Involved in the tonB-independent uptake of proteins
VCSRO45_1109	COG2885	chlorophyll binding
VCSRO45_1111	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VCSRO45_1113	COG5002	protein histidine kinase activity
VCSRO45_1113	COG0784	Response regulator, receiver
VCSRO45_1115	COG1482	cell wall glycoprotein biosynthetic process
VCSRO45_1116	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO45_1116	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO45_1116	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO45_1117	COG2207	Transcriptional regulator
VCSRO45_1119	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO45_1120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO45_1122	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VCSRO45_1124	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO45_1126	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO45_1128	COG3284	Transcriptional regulator
VCSRO45_1129	COG4628	conserved protein (DUF2132)
VCSRO45_1131	COG0415	Belongs to the DNA photolyase family
VCSRO45_1147	COG3501	Rhs element vgr protein
VCSRO45_1151	COG1715	Restriction endonuclease
VCSRO45_1152	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
VCSRO45_1153	COG0732	type I restriction modification DNA specificity domain
VCSRO45_1154	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VCSRO45_1159	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VCSRO45_1163	COG0582	viral genome integration into host DNA
VCSRO45_1164	COG0582	viral genome integration into host DNA
VCSRO45_1166	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO45_1167	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO45_1169	COG3008	intermembrane lipid transfer
VCSRO45_1169	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCSRO45_1170	COG2995	paraquat-inducible protein a
VCSRO45_1171	COG1309	transcriptional regulator
VCSRO45_1172	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO45_1176	COG1960	acyl-CoA dehydrogenase activity
VCSRO45_1177	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCSRO45_1178	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VCSRO45_1179	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
VCSRO45_1180	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VCSRO45_1183	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCSRO45_1184	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCSRO45_1185	COG0297	glycogen (starch) synthase activity
VCSRO45_1189	COG3070	regulator of competence-specific genes
VCSRO45_1190	COG1609	Transcriptional regulator
VCSRO45_1191	COG3381	protein complex oligomerization
VCSRO45_1192	COG0745	RESPONSE REGULATOR receiver
VCSRO45_1193	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCSRO45_1194	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCSRO45_1195	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VCSRO45_1196	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VCSRO45_1200	COG1032	radical SAM domain protein
VCSRO45_1202	COG0612	Peptidase, M16
VCSRO45_1205	COG0583	DNA-binding transcription factor activity
VCSRO45_1206	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VCSRO45_1208	COG2350	Protein conserved in bacteria
VCSRO45_1209	COG1607	acyl-coa hydrolase
VCSRO45_1212	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCSRO45_1213	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCSRO45_1215	COG2116	formate transmembrane transporter activity
VCSRO45_1216	COG4459	periplasmic nitrate reductase
VCSRO45_1217	COG3005	denitrification pathway
VCSRO45_1218	COG0243	molybdopterin cofactor binding
VCSRO45_1221	COG1227	inorganic diphosphatase activity
VCSRO45_1224	COG4172	Belongs to the ABC transporter superfamily
VCSRO45_1227	COG4168	peptide transport system, permease
VCSRO45_1229	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VCSRO45_1230	COG1842	Phage shock protein A
VCSRO45_1233	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO45_1236	COG2818	Glycosylase
VCSRO45_1237	COG0589	response to stress
VCSRO45_1239	COG0626	cystathionine gamma-synthase activity
VCSRO45_1241	COG0733	neurotransmitter:sodium symporter activity
VCSRO45_1242	COG0564	pseudouridine synthase activity
VCSRO45_1243	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VCSRO45_1244	COG4136	ATPase activity
VCSRO45_1245	COG4135	transport system, permease component
VCSRO45_1246	COG4134	Bacterial extracellular solute-binding protein
VCSRO45_1248	COG3313	Fe-S protein
VCSRO45_1250	COG0842	Transport permease protein
VCSRO45_1251	COG1131	(ABC) transporter
VCSRO45_1252	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO45_1253	COG0814	amino acid
VCSRO45_1256	COG2239	Acts as a magnesium transporter
VCSRO45_1257	COG0784	Response regulator, receiver
VCSRO45_1257	COG2205	protein histidine kinase activity
VCSRO45_1260	COG4934	collagen metabolic process
VCSRO45_1266	COG0840	transmembrane signaling receptor activity
VCSRO45_1268	COG2203	Gaf domain
VCSRO45_1268	COG3706	GGDEF domain
VCSRO45_1268	COG4251	negative regulation of phosphorylation
VCSRO45_1268	COG5001	Diguanylate cyclase
VCSRO45_1269	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VCSRO45_1273	COG1061	Type III restriction enzyme res subunit
VCSRO45_1274	COG1187	pseudouridine synthase activity
VCSRO45_1275	COG2814	Major facilitator Superfamily
VCSRO45_1277	COG0702	epimerase
VCSRO45_1278	COG0534	Mate efflux family protein
VCSRO45_1279	COG4181	ATPase activity
VCSRO45_1280	COG0577	efflux transmembrane transporter activity
VCSRO45_1282	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCSRO45_1284	COG1748	Saccharopine dehydrogenase
VCSRO45_1287	COG1538	Outer membrane efflux protein
VCSRO45_1291	COG0583	DNA-binding transcription factor activity
VCSRO45_1293	COG1451	nucleotide metabolic process
VCSRO45_1296	COG3063	Type IV pilus biogenesis stability protein PilW
VCSRO45_1297	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VCSRO45_1302	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO45_1305	COG3290	protein histidine kinase activity
VCSRO45_1306	COG4565	transcriptional regulatory protein
VCSRO45_1308	COG0784	Response regulator, receiver
VCSRO45_1308	COG0835	chemotaxis
VCSRO45_1316	COG1085	galactose-1-phosphate uridylyltransferase
VCSRO45_1317	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VCSRO45_1318	COG2017	converts alpha-aldose to the beta-anomer
VCSRO45_1320	COG2199	diguanylate cyclase activity
VCSRO45_1320	COG2200	EAL domain
VCSRO45_1323	COG3527	Alpha-acetolactate decarboxylase
VCSRO45_1326	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCSRO45_1328	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCSRO45_1331	COG3097	Belongs to the UPF0267 family
VCSRO45_1336	COG1271	oxidase subunit
VCSRO45_1337	COG1294	oxidase, subunit
VCSRO45_1338	COG1136	(ABC) transporter
VCSRO45_1338	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO45_1339	COG0577	efflux transmembrane transporter activity
VCSRO45_1339	COG1136	(ABC) transporter
VCSRO45_1340	COG0577	efflux transmembrane transporter activity
VCSRO45_1340	COG1136	(ABC) transporter
VCSRO45_1346	COG2723	6-phospho-beta-galactosidase activity
VCSRO45_1347	COG1609	Transcriptional regulator
VCSRO45_1348	COG0251	oxidation-reduction process
VCSRO45_1349	COG2731	YhcH YjgK YiaL family protein
VCSRO45_1350	COG0584	glycerophosphoryl diester phosphodiesterase
VCSRO45_1351	COG1349	DNA-binding transcription factor activity
VCSRO45_1352	COG3842	ATPase activity
VCSRO45_1353	COG0395	ABC-type sugar transport system, permease component
VCSRO45_1354	COG1175	transmembrane transport
VCSRO45_1357	COG0811	peptide transport
VCSRO45_1358	COG0811	peptide transport
VCSRO45_1359	COG0848	biopolymer transport protein
VCSRO45_1360	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCSRO45_1362	COG1793	dna ligase
VCSRO45_1365	COG0534	Mate efflux family protein
VCSRO45_1367	COG3001	Fructosamine kinase
VCSRO45_1369	COG0791	NLP P60 protein
VCSRO45_1370	COG0840	transmembrane signaling receptor activity
VCSRO45_1372	COG3148	PFAM DTW domain containing protein
VCSRO45_1373	COG1940	carbohydrate kinase activity
VCSRO45_1376	COG0746	molybdenum cofactor guanylyltransferase activity
VCSRO45_1377	COG3842	ATPase activity
VCSRO45_1378	COG4662	Binding-protein-dependent transport system inner membrane component
VCSRO45_1380	COG2204	response regulator
VCSRO45_1381	COG3829	transcription factor binding
VCSRO45_1382	COG3852	Histidine kinase
VCSRO45_1383	COG0488	(ABC) transporter
VCSRO45_1384	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VCSRO45_1390	COG3383	formate dehydrogenase (NAD+) activity
VCSRO45_1390	COG3383	formate dehydrogenase (NAD+) activity
VCSRO45_1391	COG0437	4 iron, 4 sulfur cluster binding
VCSRO45_1394	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VCSRO45_1395	COG1666	GTP binding
VCSRO45_1396	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO45_1399	COG2996	Protein conserved in bacteria
VCSRO45_1401	COG3008	intermembrane lipid transfer
VCSRO45_1402	COG2995	paraquat-inducible protein a
VCSRO45_1403	COG1132	(ABC) transporter
VCSRO45_1404	COG1956	GAF domain-containing protein
VCSRO45_1405	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VCSRO45_1408	COG0308	aminopeptidase N
VCSRO45_1411	COG0167	dihydroorotate dehydrogenase activity
VCSRO45_1414	COG0116	Belongs to the methyltransferase superfamily
VCSRO45_1414	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCSRO45_1416	COG0488	(ABC) transporter
VCSRO45_1419	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCSRO45_1420	COG1067	ATP-dependent peptidase activity
VCSRO45_1421	COG3120	sequence-specific DNA binding
VCSRO45_1434	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VCSRO45_1434	COG3064	Membrane
VCSRO45_1434	COG1073	alpha beta
VCSRO45_1437	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VCSRO45_1437	COG1073	alpha beta
VCSRO45_1437	COG3064	Membrane
VCSRO45_1438	COG3064	Membrane
VCSRO45_1438	COG1073	alpha beta
VCSRO45_1438	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VCSRO45_1439	COG2994	toxin metabolic process
VCSRO45_1441	COG2274	protein secretion by the type I secretion system
VCSRO45_1444	COG0784	Response regulator, receiver
VCSRO45_1444	COG2205	protein histidine kinase activity
VCSRO45_1447	COG3278	Belongs to the heme-copper respiratory oxidase family
VCSRO45_1450	COG2010	Cytochrome c
VCSRO45_1452	COG2217	Heavy metal translocating P-type atpase
VCSRO45_1455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VCSRO45_1456	COG0589	response to stress
VCSRO45_1457	COG0037	tRNA processing
VCSRO45_1461	COG3842	ATPase activity
VCSRO45_1463	COG1177	transmembrane transport
VCSRO45_1465	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCSRO45_1468	COG1115	amino acid carrier protein
VCSRO45_1472	COG1280	lysine exporter protein (LysE YggA)
VCSRO45_1476	COG3501	Rhs element vgr protein
VCSRO45_1478	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VCSRO45_1480	COG2814	Major facilitator Superfamily
VCSRO45_1481	COG1566	PFAM secretion protein HlyD family protein
VCSRO45_1482	COG1538	Outer membrane efflux protein
VCSRO45_1484	COG0513	Belongs to the DEAD box helicase family
VCSRO45_1488	COG0415	Belongs to the DNA photolyase family
VCSRO45_1489	COG0477	Major facilitator Superfamily
VCSRO45_1490	COG0583	DNA-binding transcription factor activity
VCSRO45_1491	COG0095	Lipoate-protein ligase
VCSRO45_1492	COG0443	Heat shock 70 kDa protein
VCSRO45_1495	COG1643	Atp-dependent helicase
VCSRO45_1502	COG0443	Heat shock 70 kDa protein
VCSRO45_1503	COG0443	Heat shock 70 kDa protein
VCSRO45_1510	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VCSRO45_1511	COG0602	queuosine metabolic process
VCSRO45_1513	COG0561	phosphatase activity
VCSRO45_1515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO45_1516	COG4597	amino acid ABC transporter
VCSRO45_1517	COG0765	amino acid transport
VCSRO45_1518	COG1126	abc transporter atp-binding protein
VCSRO45_1519	COG0670	Belongs to the BI1 family
VCSRO45_1520	COG2920	part of a sulfur-relay system
VCSRO45_1521	COG1254	Belongs to the acylphosphatase family
VCSRO45_1522	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCSRO45_1523	COG3706	GGDEF domain
VCSRO45_1525	COG2205	protein histidine kinase activity
VCSRO45_1525	COG3437	response regulator, receiver
VCSRO45_1525	COG3850	Histidine kinase
VCSRO45_1525	COG4999	Histidine kinase
VCSRO45_1528	COG3437	response regulator, receiver
VCSRO45_1529	COG0625	glutathione transferase activity
VCSRO45_1531	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VCSRO45_1533	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO45_1539	COG0372	Belongs to the citrate synthase family
VCSRO45_1540	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VCSRO45_1548	COG1129	ABC transporter
VCSRO45_1553	COG0745	RESPONSE REGULATOR receiver
VCSRO45_1554	COG2205	protein histidine kinase activity
VCSRO45_1555	COG3713	MltA-interacting MipA family protein
VCSRO45_1556	COG2990	Protein conserved in bacteria
VCSRO45_1558	COG2205	protein histidine kinase activity
VCSRO45_1559	COG0471	metal ion transport
VCSRO45_1561	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCSRO45_1564	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO45_1566	COG3768	UPF0283 membrane protein
VCSRO45_1567	COG3106	COG3106 Predicted ATPase
VCSRO45_1570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCSRO45_1571	COG0494	nUDIX hydrolase
VCSRO45_1572	COG0814	amino acid
VCSRO45_1573	COG1760	l-serine dehydratase
VCSRO45_1574	COG0720	synthase
VCSRO45_1575	COG0840	transmembrane signaling receptor activity
VCSRO45_1576	COG0017	Asparaginyl-tRNA synthetase
VCSRO45_1577	COG0351	phosphomethylpyrimidine kinase
VCSRO45_1578	COG3437	response regulator, receiver
VCSRO45_1578	COG2770	Histidine kinase
VCSRO45_1579	COG1448	Aminotransferase
VCSRO45_1582	COG0840	transmembrane signaling receptor activity
VCSRO45_1583	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
VCSRO45_1584	COG2943	transferase activity, transferring hexosyl groups
VCSRO45_1585	COG1609	Transcriptional regulator
VCSRO45_1586	COG3394	polysaccharide catabolic process
VCSRO45_1587	COG1486	melibiose metabolic process
VCSRO45_1588	COG1447	Phosphotransferase system cellobiose-specific component IIA
VCSRO45_1590	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VCSRO45_1591	COG0726	polysaccharide deacetylase
VCSRO45_1592	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VCSRO45_1593	COG1846	Transcriptional regulator
VCSRO45_1599	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCSRO45_1603	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCSRO45_1604	COG3108	Peptidase M15
VCSRO45_1610	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VCSRO45_1612	COG2814	Major facilitator Superfamily
VCSRO45_1614	COG1054	Belongs to the UPF0176 family
VCSRO45_1616	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCSRO45_1617	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCSRO45_1618	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCSRO45_1627	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
VCSRO45_1628	COG4139	cobalamin transport
VCSRO45_1629	COG2988	succinylglutamate desuccinylase activity
VCSRO45_1633	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VCSRO45_1634	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VCSRO45_1635	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO45_1636	COG1823	symporter activity
VCSRO45_1637	COG2925	Exonuclease
VCSRO45_1638	COG1380	Effector of murein hydrolase LrgA
VCSRO45_1639	COG1346	cytolysis
VCSRO45_1644	COG0500	methyltransferase
VCSRO45_1647	COG0776	regulation of translation
VCSRO45_1648	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO45_1648	COG0072	phenylalanine-tRNA ligase activity
VCSRO45_1649	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VCSRO45_1657	COG0322	excinuclease ABC activity
VCSRO45_1658	COG2197	response regulator
VCSRO45_1659	COG0417	DNA replication proofreading
VCSRO45_1660	COG5001	Diguanylate cyclase
VCSRO45_1662	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCSRO45_1663	COG3099	Belongs to the UPF0263 family
VCSRO45_1666	COG1228	amidohydrolase
VCSRO45_1667	COG0010	Belongs to the arginase family
VCSRO45_1668	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VCSRO45_1669	COG2986	histidine ammonia-lyase
VCSRO45_1673	COG0277	FAD linked oxidase domain protein
VCSRO45_1673	COG0247	lactate metabolic process
VCSRO45_1676	COG2885	chlorophyll binding
VCSRO45_1680	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VCSRO45_1682	COG0281	malic enzyme
VCSRO45_1684	COG2949	membrane
VCSRO45_1685	COG3706	GGDEF domain
VCSRO45_1686	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCSRO45_1688	COG0492	ferredoxin-NADP+ reductase activity
VCSRO45_1689	COG4988	ABC transporter
VCSRO45_1690	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VCSRO45_1691	COG1187	pseudouridine synthase activity
VCSRO45_1692	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO45_1693	COG0613	PHP domain protein
VCSRO45_1694	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCSRO45_1695	COG0512	Glutamine amidotransferase of anthranilate synthase
VCSRO45_1696	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VCSRO45_1697	COG0135	phosphoribosylanthranilate isomerase activity
VCSRO45_1697	COG0134	indole-3-glycerol-phosphate synthase activity
VCSRO45_1698	COG0133	tryptophan synthase activity
VCSRO45_1699	COG0159	tryptophan synthase activity
VCSRO45_1700	COG1301	dicarboxylic acid transport
VCSRO45_1701	COG1435	thymidine kinase activity
VCSRO45_1702	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VCSRO45_1703	COG1801	Protein of unknown function DUF72
VCSRO45_1704	COG4106	trans-aconitate 2-methyltransferase activity
VCSRO45_1705	COG0500	methyltransferase
VCSRO45_1706	COG4067	protein conserved in archaea
VCSRO45_1706	COG0189	ligase activity
VCSRO45_1709	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VCSRO45_1711	COG3852	Histidine kinase
VCSRO45_1714	COG3070	regulator of competence-specific genes
VCSRO45_1716	COG2431	L-lysine efflux transmembrane transporter activity
VCSRO45_1718	COG0076	glutamate decarboxylase activity
VCSRO45_1719	COG1737	Transcriptional regulator
VCSRO45_1720	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO45_1720	COG1454	alcohol dehydrogenase
VCSRO45_1721	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCSRO45_1722	COG2985	domain, Protein
VCSRO45_1722	COG3273	potassium ion transport
VCSRO45_1723	COG0542	response to heat
VCSRO45_1724	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VCSRO45_1725	COG1278	Cold shock
VCSRO45_1727	COG1187	pseudouridine synthase activity
VCSRO45_1728	COG0140	phosphoribosyl-ATP diphosphatase activity
VCSRO45_1728	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VCSRO45_1729	COG0107	imidazoleglycerol-phosphate synthase activity
VCSRO45_1730	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VCSRO45_1731	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VCSRO45_1732	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCSRO45_1732	COG0131	Imidazoleglycerol-phosphate dehydratase
VCSRO45_1733	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VCSRO45_1734	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VCSRO45_1735	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VCSRO45_1736	COG1757	Na H antiporter
VCSRO45_1737	COG2916	Histone family protein nucleoid-structuring protein H-NS
VCSRO45_1738	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO45_1739	COG0482	sulfurtransferase activity
VCSRO45_1740	COG2915	High frequency lysogenization protein hflD homolog
VCSRO45_1741	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VCSRO45_1743	COG2268	Band 7 protein
VCSRO45_1745	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VCSRO45_1748	COG0300	oxidoreductase activity
VCSRO45_1750	COG0501	Belongs to the peptidase M48B family
VCSRO45_1752	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VCSRO45_1753	COG2226	methyltransferase
VCSRO45_1754	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO45_1755	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCSRO45_1756	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VCSRO45_1757	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VCSRO45_1758	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VCSRO45_1759	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VCSRO45_1760	COG0653	protein targeting
VCSRO45_1761	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO45_1762	COG2199	diguanylate cyclase activity
VCSRO45_1762	COG2203	Gaf domain
VCSRO45_1764	COG4120	Belongs to the binding-protein-dependent transport system permease family
VCSRO45_1766	COG4628	conserved protein (DUF2132)
VCSRO45_1767	COG3092	negative regulation of chromosome organization
VCSRO45_1768	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCSRO45_1769	COG0280	phosphate acetyltransferase
VCSRO45_1769	COG0857	belongs to the CobB CobQ family
VCSRO45_1770	COG0435	Glutathione S-transferase
VCSRO45_1771	COG4608	Belongs to the ABC transporter superfamily
VCSRO45_1772	COG0444	Belongs to the ABC transporter superfamily
VCSRO45_1773	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO45_1774	COG0601	transmembrane transport
VCSRO45_1778	COG2204	response regulator
VCSRO45_1779	COG5001	Diguanylate cyclase
VCSRO45_1779	COG3300	MHYT domain
VCSRO45_1780	COG4191	Histidine kinase
VCSRO45_1781	COG5002	protein histidine kinase activity
VCSRO45_1783	COG2201	protein-glutamate methylesterase activity
VCSRO45_1786	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO45_1789	COG1881	PFAM PEBP family protein
VCSRO45_1795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO45_1796	COG0640	Transcriptional regulator
VCSRO45_1797	COG3706	GGDEF domain
VCSRO45_1801	COG1946	Acyl-CoA thioesterase
VCSRO45_1802	COG1522	sequence-specific DNA binding
VCSRO45_1804	COG0616	signal peptide processing
VCSRO45_1805	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO45_1808	COG2983	Belongs to the UPF0260 family
VCSRO45_1810	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VCSRO45_1811	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VCSRO45_1813	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VCSRO45_1814	COG2832	Protein of unknown function (DUF454)
VCSRO45_1816	COG0745	RESPONSE REGULATOR receiver
VCSRO45_1817	COG0583	DNA-binding transcription factor activity
VCSRO45_1818	COG0778	Nitroreductase
VCSRO45_1819	COG1024	Enoyl-CoA hydratase
VCSRO45_1819	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCSRO45_1820	COG0183	Belongs to the thiolase family
VCSRO45_1823	COG2067	long-chain fatty acid transport protein
VCSRO45_1825	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VCSRO45_1826	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VCSRO45_1827	COG2982	Protein involved in outer membrane biogenesis
VCSRO45_1828	COG0572	uridine kinase
VCSRO45_1829	COG0489	protein tyrosine kinase activity
VCSRO45_1830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO45_1830	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO45_1833	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO45_1835	COG0617	tRNA 3'-terminal CCA addition
VCSRO45_1835	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
VCSRO45_1835	COG0517	IMP dehydrogenase activity
VCSRO45_1836	COG2199	diguanylate cyclase activity
VCSRO45_1837	COG0314	molybdopterin synthase activity
VCSRO45_1838	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VCSRO45_1839	COG0315	cyclic pyranopterin monophosphate synthase activity
VCSRO45_1840	COG0521	Mo-molybdopterin cofactor biosynthetic process
VCSRO45_1841	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VCSRO45_1842	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VCSRO45_1843	COG2198	Histidine kinase
VCSRO45_1844	COG2204	response regulator
VCSRO45_1845	COG0556	nucleotide-excision repair
VCSRO45_1847	COG4657	Part of a membrane complex involved in electron transport
VCSRO45_1848	COG2878	Part of a membrane complex involved in electron transport
VCSRO45_1849	COG4656	Part of a membrane complex involved in electron transport
VCSRO45_1852	COG4660	Part of a membrane complex involved in electron transport
VCSRO45_1853	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VCSRO45_1854	COG0346	lactoylglutathione lyase activity
VCSRO45_1857	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VCSRO45_1858	COG2056	Na+-H+ antiporter family
VCSRO45_1859	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VCSRO45_1860	COG1286	toxin biosynthetic process
VCSRO45_1861	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VCSRO45_1862	COG0285	dihydrofolate synthase activity
VCSRO45_1863	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VCSRO45_1864	COG0101	tRNA pseudouridine synthase activity
VCSRO45_1867	COG1263	PTS System
VCSRO45_1867	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO45_1867	COG2190	(PTS) system
VCSRO45_1868	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VCSRO45_1869	COG1846	Transcriptional regulator
VCSRO45_1869	COG1940	carbohydrate kinase activity
VCSRO45_1870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCSRO45_1870	COG4651	solute:proton antiporter activity
VCSRO45_1871	COG0367	asparagine synthase
VCSRO45_1874	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VCSRO45_1875	COG0563	adenylate kinase activity
VCSRO45_1876	COG0326	Molecular chaperone. Has ATPase activity
VCSRO45_1877	COG3710	Transcriptional regulator
VCSRO45_1880	COG0622	Phosphoesterase
VCSRO45_1881	COG1090	epimerase
VCSRO45_1882	COG0300	oxidoreductase activity
VCSRO45_1883	COG3118	belongs to the thioredoxin family
VCSRO45_1885	COG0330	HflC and HflK could
VCSRO45_1886	COG1585	Membrane protein implicated in regulation of membrane protease activity
VCSRO45_1887	COG0789	Transcriptional regulator
VCSRO45_1890	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VCSRO45_1891	COG3115	cell septum assembly
VCSRO45_1892	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VCSRO45_1893	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VCSRO45_1894	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO45_1896	COG2190	(PTS) system
VCSRO45_1897	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO45_1898	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCSRO45_1899	COG1702	phosphate starvation-inducible protein PhoH
VCSRO45_1900	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VCSRO45_1901	COG4535	Mg2 and Co2 transporter CorC
VCSRO45_1902	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VCSRO45_1903	COG2888	peptidyl-tyrosine sulfation
VCSRO45_1904	COG0495	leucyl-tRNA aminoacylation
VCSRO45_1905	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VCSRO45_1906	COG1466	dna polymerase III delta subunit
VCSRO45_1907	COG0799	negative regulation of ribosome biogenesis
VCSRO45_1908	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VCSRO45_1909	COG0768	penicillin binding
VCSRO45_1910	COG0772	Belongs to the SEDS family
VCSRO45_1911	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCSRO45_1912	COG1686	Belongs to the peptidase S11 family
VCSRO45_1913	COG2921	Belongs to the UPF0250 family
VCSRO45_1914	COG0321	lipoyl(octanoyl) transferase activity
VCSRO45_1915	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VCSRO45_1917	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCSRO45_1922	COG1596	polysaccharide export
VCSRO45_1924	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCSRO45_1931	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
VCSRO45_1939	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VCSRO45_1940	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VCSRO45_1941	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VCSRO45_1942	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO45_1947	COG0366	Alpha amylase catalytic
VCSRO45_1948	COG1263	PTS System
VCSRO45_1948	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO45_1949	COG1609	Transcriptional regulator
VCSRO45_1950	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCSRO45_1951	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VCSRO45_1952	COG2011	ABC-type metal ion transport system permease component
VCSRO45_1953	COG1464	Belongs to the NlpA lipoprotein family
VCSRO45_1954	COG3385	transposase activity
VCSRO45_1955	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VCSRO45_1957	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCSRO45_1957	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCSRO45_1960	COG1611	Belongs to the LOG family
VCSRO45_1961	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO45_1962	COG2363	Small membrane protein
VCSRO45_1963	COG0583	DNA-binding transcription factor activity
VCSRO45_1964	COG0301	tRNA thio-modification
VCSRO45_1964	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO45_1966	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VCSRO45_1967	COG1722	exodeoxyribonuclease VII activity
VCSRO45_1968	COG0142	geranyltranstransferase activity
VCSRO45_1969	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VCSRO45_1970	COG0564	pseudouridine synthase activity
VCSRO45_1971	COG3098	single-species biofilm formation
VCSRO45_1974	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO45_1976	COG1671	Belongs to the UPF0178 family
VCSRO45_1977	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCSRO45_1978	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCSRO45_1979	COG0254	rRNA binding
VCSRO45_1980	COG1720	tRNA m6t6A37 methyltransferase activity
VCSRO45_1981	COG0442	prolyl-tRNA aminoacylation
VCSRO45_1985	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VCSRO45_1985	COG0047	phosphoribosylformylglycinamidine synthase activity
VCSRO45_1986	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VCSRO45_1989	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCSRO45_1995	COG0484	heat shock protein binding
VCSRO45_1996	COG0443	Heat shock 70 kDa protein
VCSRO45_1997	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VCSRO45_1998	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VCSRO45_1999	COG0497	DNA recombination
VCSRO45_2000	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO45_2001	COG2914	Belongs to the UPF0125 (RnfH) family
VCSRO45_2002	COG2867	negative regulation of translational initiation
VCSRO45_2003	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VCSRO45_2005	COG0582	viral genome integration into host DNA
VCSRO45_2017	COG0210	DNA helicase
VCSRO45_2021	COG3501	Rhs element vgr protein
VCSRO45_2037	COG2003	Belongs to the UPF0758 family
VCSRO45_2049	COG1061	Type III restriction enzyme res subunit
VCSRO45_2052	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VCSRO45_2053	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VCSRO45_2054	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCSRO45_2058	COG3051	citrate lyase alpha subunit
VCSRO45_2059	COG2301	Belongs to the HpcH HpaI aldolase family
VCSRO45_2061	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
VCSRO45_2063	COG3630	sodium ion export across plasma membrane
VCSRO45_2064	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO45_2064	COG5016	pyruvate
VCSRO45_2065	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCSRO45_2067	COG4565	transcriptional regulatory protein
VCSRO45_2070	COG0583	DNA-binding transcription factor activity
VCSRO45_2072	COG1115	amino acid carrier protein
VCSRO45_2073	COG2977	Belongs to the P-Pant transferase superfamily
VCSRO45_2074	COG1120	ATPase activity
VCSRO45_2075	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO45_2076	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO45_2077	COG4592	Periplasmic binding protein
VCSRO45_2079	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO45_2080	COG1169	isochorismate synthase
VCSRO45_2081	COG1021	2,3-dihydroxybenzoate-AMP ligase
VCSRO45_2082	COG1535	isochorismatase
VCSRO45_2082	COG3433	isochorismatase activity
VCSRO45_2083	COG1584	GPR1 FUN34 yaaH family protein
VCSRO45_2085	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VCSRO45_2085	COG0519	Catalyzes the synthesis of GMP from XMP
VCSRO45_2086	COG0516	GMP reductase activity
VCSRO45_2086	COG0517	IMP dehydrogenase activity
VCSRO45_2087	COG1570	exodeoxyribonuclease VII activity
VCSRO45_2090	COG1160	GTP binding
VCSRO45_2091	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO45_2092	COG2976	Protein conserved in bacteria
VCSRO45_2093	COG0124	histidyl-tRNA synthetase
VCSRO45_2094	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VCSRO45_2097	COG0105	UTP biosynthetic process
VCSRO45_2098	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCSRO45_2099	COG2975	iron-sulfur cluster assembly
VCSRO45_2100	COG0633	Ferredoxin
VCSRO45_2104	COG0822	iron-sulfur transferase activity
VCSRO45_2106	COG1959	2 iron, 2 sulfur cluster binding
VCSRO45_2108	COG0483	inositol monophosphate 1-phosphatase activity
VCSRO45_2109	COG3385	transposase activity
VCSRO45_2110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO45_2111	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO45_2112	COG1862	Preprotein translocase
VCSRO45_2114	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
VCSRO45_2115	COG0517	IMP dehydrogenase activity
VCSRO45_2117	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VCSRO45_2118	COG0583	DNA-binding transcription factor activity
VCSRO45_2119	COG0450	alkyl hydroperoxide reductase
VCSRO45_2120	COG3142	Participates in the control of copper homeostasis
VCSRO45_2123	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCSRO45_2124	COG0581	inorganic phosphate transmembrane transporter activity
VCSRO45_2126	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VCSRO45_2127	COG0248	Ppx GppA phosphatase
VCSRO45_2129	COG5002	protein histidine kinase activity
VCSRO45_2130	COG0745	RESPONSE REGULATOR receiver
VCSRO45_2132	COG0826	peptidase U32
VCSRO45_2133	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCSRO45_2141	COG0542	response to heat
VCSRO45_2142	COG1496	oxidoreductase activity
VCSRO45_2143	COG0564	pseudouridine synthase activity
VCSRO45_2144	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO45_2145	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCSRO45_2146	COG0077	Prephenate dehydratase
VCSRO45_2146	COG1605	Chorismate mutase
VCSRO45_2147	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCSRO45_2148	COG5001	Diguanylate cyclase
VCSRO45_2150	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VCSRO45_2152	COG0488	(ABC) transporter
VCSRO45_2154	COG0287	Prephenate dehydrogenase
VCSRO45_2154	COG1605	Chorismate mutase
VCSRO45_2155	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO45_2156	COG3275	phosphorelay sensor kinase activity
VCSRO45_2157	COG3279	Response regulator of the LytR AlgR family
VCSRO45_2159	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VCSRO45_2160	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCSRO45_2162	COG1966	Carbon starvation protein
VCSRO45_2163	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VCSRO45_2164	COG1047	Peptidyl-prolyl cis-trans
VCSRO45_2165	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VCSRO45_2167	COG0196	riboflavin kinase activity
VCSRO45_2168	COG0728	peptidoglycan biosynthetic process
VCSRO45_2169	COG0268	Binds directly to 16S ribosomal RNA
VCSRO45_2170	COG0640	Transcriptional regulator
VCSRO45_2171	COG0583	DNA-binding transcription factor activity
VCSRO45_2172	COG1283	sodium-dependent phosphate transmembrane transporter activity
VCSRO45_2174	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VCSRO45_2175	COG0730	response to heat
VCSRO45_2176	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
VCSRO45_2177	COG0494	nUDIX hydrolase
VCSRO45_2179	COG0667	Aldo Keto reductase
VCSRO45_2181	COG2204	response regulator
VCSRO45_2183	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VCSRO45_2184	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VCSRO45_2187	COG0513	Belongs to the DEAD box helicase family
VCSRO45_2192	COG3153	acetyltransferase
VCSRO45_2193	COG3154	lipid carrier protein
VCSRO45_2195	COG0826	peptidase U32
VCSRO45_2196	COG0826	peptidase U32
VCSRO45_2202	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VCSRO45_2204	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VCSRO45_2205	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VCSRO45_2206	COG0195	Participates in both transcription termination and antitermination
VCSRO45_2207	COG0779	Required for maturation of 30S ribosomal subunits
VCSRO45_2210	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCSRO45_2213	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VCSRO45_2214	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VCSRO45_2215	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VCSRO45_2216	COG1534	Rna-binding protein
VCSRO45_2217	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO45_2219	COG2027	D-alanyl-D-alanine carboxypeptidase
VCSRO45_2220	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCSRO45_2221	COG0739	heme binding
VCSRO45_2224	COG0316	Belongs to the HesB IscA family
VCSRO45_2225	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VCSRO45_2227	COG0628	permease
VCSRO45_2228	COG2813	Specifically methylates the guanine in position
VCSRO45_2229	COG2205	protein histidine kinase activity
VCSRO45_2229	COG0784	Response regulator, receiver
VCSRO45_2230	COG0747	negative chemotaxis
VCSRO45_2231	COG0601	transmembrane transport
VCSRO45_2232	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO45_2233	COG0444	Belongs to the ABC transporter superfamily
VCSRO45_2234	COG4608	Belongs to the ABC transporter superfamily
VCSRO45_2236	COG2971	BadF BadG BcrA BcrD
VCSRO45_2240	COG3842	ATPase activity
VCSRO45_2242	COG1840	ABC-type Fe3 transport system, periplasmic component
VCSRO45_2243	COG0004	ammonium transporteR
VCSRO45_2244	COG0347	Belongs to the P(II) protein family
VCSRO45_2245	COG3112	Uncharacterised protein family (UPF0231)
VCSRO45_2246	COG1049	propionate catabolic process, 2-methylcitrate cycle
VCSRO45_2247	COG1752	Esterase of the alpha-beta hydrolase superfamily
VCSRO45_2248	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VCSRO45_2249	COG1643	Atp-dependent helicase
VCSRO45_2251	COG1489	DNA binding
VCSRO45_2253	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCSRO45_2255	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCSRO45_2256	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VCSRO45_2257	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VCSRO45_2258	COG0842	Transport permease protein
VCSRO45_2259	COG1131	(ABC) transporter
VCSRO45_2260	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO45_2261	COG0288	reversible hydration of carbon dioxide
VCSRO45_2264	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VCSRO45_2265	COG3107	peptidoglycan biosynthetic process
VCSRO45_2266	COG0792	nuclease activity
VCSRO45_2267	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCSRO45_2268	COG2823	Periplasmic or secreted lipoprotein
VCSRO45_2269	COG2969	positive regulation of protein catabolic process
VCSRO45_2270	COG0625	glutathione transferase activity
VCSRO45_2271	COG2857	Cytochrome c1
VCSRO45_2272	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VCSRO45_2273	COG0723	plastoquinol--plastocyanin reductase activity
VCSRO45_2274	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VCSRO45_2275	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VCSRO45_2276	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VCSRO45_2278	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCSRO45_2279	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCSRO45_2280	COG0335	large ribosomal subunit rRNA binding
VCSRO45_2281	COG0336	Belongs to the RNA methyltransferase TrmD family
VCSRO45_2282	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VCSRO45_2283	COG0228	four-way junction DNA binding
VCSRO45_2284	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VCSRO45_2286	COG4137	Cytochrome C assembly protein
VCSRO45_2287	COG4536	flavin adenine dinucleotide binding
VCSRO45_2288	COG1854	S-ribosylhomocysteine lyase activity
VCSRO45_2289	COG2918	glutathione biosynthetic process
VCSRO45_2290	COG0612	Peptidase, M16
VCSRO45_2291	COG1238	metal cluster binding
VCSRO45_2293	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCSRO45_2294	COG5016	pyruvate
VCSRO45_2294	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO45_2295	COG3630	sodium ion export across plasma membrane
VCSRO45_2305	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
VCSRO45_2306	COG0527	aspartate kinase activity
VCSRO45_2307	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VCSRO45_2308	COG2137	regulation of response to DNA damage stimulus
VCSRO45_2309	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VCSRO45_2311	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
VCSRO45_2312	COG4208	sulfate ABC transporter
VCSRO45_2316	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VCSRO45_2318	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCSRO45_2319	COG1388	LysM domain
VCSRO45_2319	COG4942	peptidase
VCSRO45_2320	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VCSRO45_2321	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VCSRO45_2322	COG0585	pseudouridine synthase activity
VCSRO45_2323	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VCSRO45_2324	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VCSRO45_2325	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VCSRO45_2326	COG1968	undecaprenyl-diphosphatase activity
VCSRO45_2327	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCSRO45_2328	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VCSRO45_2329	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VCSRO45_2331	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VCSRO45_2332	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VCSRO45_2333	COG1610	YqeY-like protein
VCSRO45_2334	COG0358	DNA primase activity
VCSRO45_2338	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCSRO45_2348	COG0840	transmembrane signaling receptor activity
VCSRO45_2351	COG3547	Transposase (IS116 IS110 IS902 family)
VCSRO45_2352	COG2801	Transposase and inactivated derivatives
VCSRO45_2353	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VCSRO45_2354	COG1349	DNA-binding transcription factor activity
VCSRO45_2359	COG1279	arginine transmembrane transporter activity
VCSRO45_2360	COG0668	transmembrane transport
VCSRO45_2361	COG0191	fructose-bisphosphate aldolase activity
VCSRO45_2362	COG0126	phosphoglycerate kinase activity
VCSRO45_2363	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO45_2364	COG4771	TonB-dependent receptor
VCSRO45_2365	COG0583	DNA-binding transcription factor activity
VCSRO45_2366	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCSRO45_2367	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VCSRO45_2368	COG3091	SprT-like family
VCSRO45_2369	COG2356	endonuclease I
VCSRO45_2370	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VCSRO45_2371	COG0189	ligase activity
VCSRO45_2372	COG1678	Uncharacterized ACR, COG1678
VCSRO45_2373	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VCSRO45_2374	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCSRO45_2378	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VCSRO45_2379	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VCSRO45_2380	COG0762	integral membrane protein
VCSRO45_2383	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VCSRO45_2384	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VCSRO45_2385	COG2066	Belongs to the glutaminase family
VCSRO45_2386	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VCSRO45_2387	COG1194	a g-specific adenine glycosylase
VCSRO45_2388	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VCSRO45_2389	COG0741	lytic transglycosylase activity
VCSRO45_2400	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VCSRO45_2401	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VCSRO45_2402	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO45_2403	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VCSRO45_2404	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VCSRO45_2405	COG2967	ApaG domain
VCSRO45_2406	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VCSRO45_2408	COG3610	response to peptide
VCSRO45_2409	COG2966	Psort location CytoplasmicMembrane, score
VCSRO45_2410	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VCSRO45_2411	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VCSRO45_2412	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VCSRO45_2413	COG0142	geranyltranstransferase activity
VCSRO45_2414	COG0531	amino acid
VCSRO45_2415	COG0039	L-malate dehydrogenase activity
VCSRO45_2416	COG1438	arginine binding
VCSRO45_2417	COG2358	TRAP transporter, solute receptor (TAXI family
VCSRO45_2419	COG0589	response to stress
VCSRO45_2424	COG2235	arginine
VCSRO45_2425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCSRO45_2426	COG1151	hydroxylamine reductase activity
VCSRO45_2427	COG0312	modulator of DNA gyrase
VCSRO45_2428	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VCSRO45_2429	COG3164	Protein of unknown function
VCSRO45_2431	COG0424	maF-like protein
VCSRO45_2432	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VCSRO45_2433	COG1792	Involved in formation and maintenance of cell shape
VCSRO45_2434	COG1077	Cell shape determining protein MreB Mrl
VCSRO45_2440	COG2165	general secretion pathway protein
VCSRO45_2441	COG2165	general secretion pathway protein
VCSRO45_2443	COG1459	type II secretion system
VCSRO45_2444	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO45_2446	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO45_2446	COG3267	Type II secretory pathway component ExeA
VCSRO45_2451	COG2200	EAL domain
VCSRO45_2451	COG2199	diguanylate cyclase activity
VCSRO45_2452	COG0629	single-stranded DNA binding
VCSRO45_2455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VCSRO45_2457	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCSRO45_2458	COG0527	aspartate kinase activity
VCSRO45_2459	COG1410	methionine synthase
VCSRO45_2459	COG0646	methionine synthase
VCSRO45_2475	COG0175	sulfate reduction
VCSRO45_2477	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCSRO45_2481	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO45_2482	COG0735	belongs to the Fur family
VCSRO45_2485	COG0166	Belongs to the GPI family
VCSRO45_2486	COG0432	Pfam Uncharacterised protein family UPF0047
VCSRO45_2487	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCSRO45_2490	COG0359	binds to the 23S rRNA
VCSRO45_2491	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
VCSRO45_2492	COG2965	DNA replication, synthesis of RNA primer
VCSRO45_2493	COG0360	Binds together with S18 to 16S ribosomal RNA
VCSRO45_2495	COG2906	2 iron, 2 sulfur cluster binding
VCSRO45_2496	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCSRO45_2497	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCSRO45_2498	COG0049	tRNA binding
VCSRO45_2501	COG2923	Belongs to the DsrF TusC family
VCSRO45_2502	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VCSRO45_2503	COG2964	Protein conserved in bacteria
VCSRO45_2504	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO45_2506	COG2900	Belongs to the SlyX family
VCSRO45_2507	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VCSRO45_2508	COG0330	HflC and HflK could
VCSRO45_2509	COG0330	HflC and HflK could
VCSRO45_2510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VCSRO45_2511	COG1923	regulation of RNA biosynthetic process
VCSRO45_2512	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VCSRO45_2513	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VCSRO45_2515	COG0802	atpase or kinase
VCSRO45_2516	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VCSRO45_2525	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VCSRO45_2526	COG1162	GTPase activity
VCSRO45_2527	COG0688	phosphatidylethanolamine metabolic process
VCSRO45_2528	COG0471	metal ion transport
VCSRO45_2530	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VCSRO45_2531	COG4942	peptidase
VCSRO45_2534	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VCSRO45_2535	COG2816	NAD+ diphosphatase activity
VCSRO45_2536	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VCSRO45_2537	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VCSRO45_2538	COG0085	RNA polymerase activity
VCSRO45_2539	COG0222	ribosome binding
VCSRO45_2540	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VCSRO45_2542	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VCSRO45_2543	COG0250	Participates in transcription elongation, termination and antitermination
VCSRO45_2544	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCSRO45_2545	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCSRO45_2550	COG1072	(Pantothenic acid kinase))
VCSRO45_2552	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VCSRO45_2554	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VCSRO45_2563	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VCSRO45_2566	COG3118	belongs to the thioredoxin family
VCSRO45_2567	COG0513	Belongs to the DEAD box helicase family
VCSRO45_2568	COG0248	Ppx GppA phosphatase
VCSRO45_2569	COG2205	protein histidine kinase activity
VCSRO45_2569	COG0784	Response regulator, receiver
VCSRO45_2570	COG2814	Major facilitator Superfamily
VCSRO45_2573	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCSRO45_2574	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VCSRO45_2575	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO45_2576	COG0439	Biotin carboxylase
VCSRO45_2577	COG2264	protein methyltransferase activity
VCSRO45_2578	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO45_2579	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VCSRO45_2585	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VCSRO45_2586	COG1518	maintenance of DNA repeat elements
VCSRO45_2588	COG1857	crispr-associated protein
VCSRO45_2595	COG1609	Transcriptional regulator
VCSRO45_2596	COG0129	dihydroxy-acid dehydratase activity
VCSRO45_2597	COG3265	gluconokinase activity
VCSRO45_2599	COG0800	Aldolase
VCSRO45_2602	COG0840	transmembrane signaling receptor activity
VCSRO45_2603	COG1982	Orn Lys Arg decarboxylase major
VCSRO45_2604	COG0531	amino acid
VCSRO45_2605	COG3710	Transcriptional regulator
VCSRO45_2606	COG0789	Transcriptional regulator
VCSRO45_2608	COG0151	Belongs to the GarS family
VCSRO45_2610	COG0776	regulation of translation
VCSRO45_2611	COG1253	flavin adenine dinucleotide binding
VCSRO45_2612	COG3068	Protein conserved in bacteria
VCSRO45_2614	COG1573	uracil-dna glycosylase
VCSRO45_2615	COG0668	transmembrane transport
VCSRO45_2616	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VCSRO45_2618	COG3385	transposase activity
VCSRO45_2620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCSRO45_2622	COG1216	Glycosyl transferase, family 2
VCSRO45_2626	COG1051	belongs to the nudix hydrolase family
VCSRO45_2627	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCSRO45_2628	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
VCSRO45_2631	COG0438	transferase activity, transferring glycosyl groups
VCSRO45_2632	COG1216	Glycosyl transferase, family 2
VCSRO45_2636	COG5433	transposase activity
VCSRO45_2637	COG5433	transposase activity
VCSRO45_2638	COG5433	transposase activity
VCSRO45_2639	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
VCSRO45_2645	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO45_2647	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCSRO45_2654	COG1519	Transferase
VCSRO45_2659	COG3642	lipopolysaccharide core region biosynthetic process
VCSRO45_2660	COG0859	PFAM glycosyl transferase family 9
VCSRO45_2661	COG0463	Glycosyl transferase, family 2
VCSRO45_2662	COG0463	Glycosyl transferase, family 2
VCSRO45_2663	COG0859	PFAM glycosyl transferase family 9
VCSRO45_2664	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VCSRO45_2665	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VCSRO45_2667	COG0267	Belongs to the bacterial ribosomal protein bL33 family
VCSRO45_2668	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VCSRO45_2669	COG2003	Belongs to the UPF0758 family
VCSRO45_2671	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VCSRO45_2672	COG1309	transcriptional regulator
VCSRO45_2673	COG1560	Kdo2-lipid A biosynthetic process
VCSRO45_2674	COG1560	Kdo2-lipid A biosynthetic process
VCSRO45_2675	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VCSRO45_2676	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VCSRO45_2677	COG1561	YicC-like family, N-terminal region
VCSRO45_2685	COG2003	Belongs to the UPF0758 family
VCSRO45_2692	COG0328	RNA-DNA hybrid ribonuclease activity
VCSRO45_2698	COG2862	Uncharacterized protein family, UPF0114
VCSRO45_2699	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO45_2699	COG1263	PTS System
VCSRO45_2700	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCSRO45_2703	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VCSRO45_2704	COG1120	ATPase activity
VCSRO45_2705	COG4774	siderophore transport
VCSRO45_2706	COG1132	(ABC) transporter
VCSRO45_2709	COG0514	ATP-dependent DNA helicase (RecQ)
VCSRO45_2710	COG2962	Rard protein
VCSRO45_2711	COG0405	Gamma-glutamyltransferase
VCSRO45_2713	COG1280	lysine exporter protein (LysE YggA)
VCSRO45_2714	COG0210	DNA helicase
VCSRO45_2716	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VCSRO45_2717	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO45_2719	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO45_2720	COG0601	transmembrane transport
VCSRO45_2721	COG0747	negative chemotaxis
VCSRO45_2730	COG1309	transcriptional regulator
VCSRO45_2731	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO45_2732	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO45_2733	COG2960	long-chain fatty acid transporting porin activity
VCSRO45_2734	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VCSRO45_2735	COG0583	DNA-binding transcription factor activity
VCSRO45_2748	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
VCSRO45_2749	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCSRO45_2750	COG1739	Uncharacterized protein family UPF0029
VCSRO45_2751	COG1024	Enoyl-CoA hydratase
VCSRO45_2751	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCSRO45_2752	COG0183	Belongs to the thiolase family
VCSRO45_2753	COG0583	DNA-binding transcription factor activity
VCSRO45_2754	COG2814	Major facilitator Superfamily
VCSRO45_2756	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VCSRO45_2757	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VCSRO45_2758	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VCSRO45_2759	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VCSRO45_2760	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VCSRO45_2761	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VCSRO45_2763	COG0356	it plays a direct role in the translocation of protons across the membrane
VCSRO45_2764	COG3312	ion transport
VCSRO45_2765	COG1475	DNA binding
VCSRO45_2766	COG1192	Involved in chromosome partitioning
VCSRO45_2767	COG0357	Ribosomal RNA small subunit methyltransferase G
VCSRO45_2768	COG0445	tRNA wobble uridine modification
VCSRO45_2773	COG0217	transcriptional regulatory protein
VCSRO45_2774	COG2084	Dehydrogenase
VCSRO45_2777	COG2909	trisaccharide binding
VCSRO45_2778	COG0058	SHG alpha-glucan phosphorylase activity
VCSRO45_2779	COG1640	4-alpha-glucanotransferase
VCSRO45_2780	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VCSRO45_2783	COG3501	Rhs element vgr protein
VCSRO45_2790	COG0471	metal ion transport
VCSRO45_2791	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCSRO45_2799	COG0671	phosphoesterase, PA-phosphatase related
VCSRO45_2800	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VCSRO45_2802	COG1999	signal sequence binding
VCSRO45_2805	COG0786	glutamate:sodium symporter activity
VCSRO45_2812	COG0813	purine-nucleoside phosphorylase activity
VCSRO45_2813	COG3272	Protein of unknown function (DUF1722)
VCSRO45_2815	COG0415	Belongs to the DNA photolyase family
VCSRO45_2816	COG1376	ErfK ybiS ycfS ynhG family protein
VCSRO45_2816	COG1388	LysM domain
VCSRO45_2818	COG0513	Belongs to the DEAD box helicase family
VCSRO45_2819	COG1770	oligopeptidase
VCSRO45_2824	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCSRO45_2825	COG0573	inorganic phosphate transmembrane transporter activity
VCSRO45_2826	COG0581	inorganic phosphate transmembrane transporter activity
VCSRO45_2827	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCSRO45_2830	COG3314	Sporulation integral membrane protein YlbJ
VCSRO45_2831	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO45_2833	COG0739	heme binding
VCSRO45_2834	COG3300	MHYT domain
VCSRO45_2834	COG5001	Diguanylate cyclase
VCSRO45_2836	COG0583	DNA-binding transcription factor activity
VCSRO45_2837	COG2814	Major facilitator Superfamily
VCSRO45_2842	COG1301	dicarboxylic acid transport
VCSRO45_2844	COG1342	Belongs to the UPF0251 family
VCSRO45_2850	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VCSRO45_2851	COG0673	inositol 2-dehydrogenase activity
VCSRO45_2853	COG2200	EAL domain
VCSRO45_2853	COG2771	luxR family
VCSRO45_2854	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO45_2856	COG0564	pseudouridine synthase activity
VCSRO45_2869	COG3829	transcription factor binding
VCSRO45_2874	COG3501	Rhs element vgr protein
VCSRO45_2874	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO45_2878	COG1869	D-ribose catabolic process
VCSRO45_2879	COG1129	ABC transporter
VCSRO45_2880	COG1172	Belongs to the binding-protein-dependent transport system permease family
VCSRO45_2881	COG1879	ABC-type sugar transport system periplasmic component
VCSRO45_2882	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO45_2883	COG1609	Transcriptional regulator
VCSRO45_2886	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO45_2888	COG0584	glycerophosphoryl diester phosphodiesterase
VCSRO45_2889	COG2271	Major facilitator Superfamily
VCSRO45_2896	COG0579	oxidoreductase
VCSRO45_2898	COG0242	peptide deformylase activity
VCSRO45_2901	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO45_2902	COG1609	Transcriptional regulator
VCSRO45_2903	COG1017	nitric oxide dioxygenase activity
VCSRO45_2903	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCSRO45_2904	COG1320	monovalent cation:proton antiporter activity
VCSRO45_2905	COG2212	antiporter activity
VCSRO45_2906	COG1863	multisubunit Na H antiporter MnhE subunit
VCSRO45_2907	COG0651	ATP synthesis coupled electron transport
VCSRO45_2908	COG1006	Multisubunit Na H antiporter MnhC subunit
VCSRO45_2909	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCSRO45_2909	COG2111	Na H antiporter
VCSRO45_2911	COG0589	response to stress
VCSRO45_2912	COG0814	amino acid
VCSRO45_2915	COG3530	Putative quorum-sensing-regulated virulence factor
VCSRO45_2917	COG5002	protein histidine kinase activity
VCSRO45_2917	COG5001	Diguanylate cyclase
VCSRO45_2918	COG1278	Cold shock
VCSRO45_2921	COG2304	oxidoreductase activity
VCSRO45_2925	COG0714	Associated with various cellular activities
VCSRO45_2926	COG0840	transmembrane signaling receptor activity
VCSRO45_2929	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO45_2930	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO45_2932	COG3604	Transcriptional regulator
VCSRO45_2933	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCSRO45_2933	COG1017	nitric oxide dioxygenase activity
VCSRO45_2934	COG1278	Cold shock
VCSRO45_2935	COG3036	rescue of stalled ribosome
VCSRO45_2940	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VCSRO45_2940	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VCSRO45_2941	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCSRO45_2943	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCSRO45_2946	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
VCSRO45_2947	COG0516	GMP reductase activity
VCSRO45_2955	COG1175	transmembrane transport
VCSRO45_2956	COG0395	ABC-type sugar transport system, permease component
VCSRO45_2957	COG5578	integral membrane protein
VCSRO45_2962	COG1609	Transcriptional regulator
VCSRO45_2964	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
VCSRO45_2965	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
VCSRO45_2967	COG4580	involved in the transport of maltose and maltodextrins
VCSRO45_2968	COG0840	transmembrane signaling receptor activity
VCSRO45_2969	COG1482	cell wall glycoprotein biosynthetic process
VCSRO45_2972	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
VCSRO45_2976	COG0513	Belongs to the DEAD box helicase family
VCSRO45_2977	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCSRO45_2978	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VCSRO45_2979	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VCSRO45_2980	COG0784	Response regulator, receiver
VCSRO45_2980	COG3437	response regulator, receiver
VCSRO45_2981	COG4191	Histidine kinase
VCSRO45_2981	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO45_2983	COG1757	Na H antiporter
VCSRO45_2984	COG2814	Major facilitator Superfamily
VCSRO45_2986	COG3706	GGDEF domain
VCSRO45_2987	COG3240	lipase activity
VCSRO45_2989	COG0840	transmembrane signaling receptor activity
VCSRO45_2990	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VCSRO45_2991	COG5380	lipid catabolic process
VCSRO45_2996	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO45_2997	COG4605	iron ion homeostasis
VCSRO45_2998	COG4604	ABC transporter, ATP-binding protein
VCSRO45_2999	COG2207	Transcriptional regulator
VCSRO45_3002	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCSRO45_3010	COG0348	domain, Protein
VCSRO45_3015	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
VCSRO45_3020	COG3290	protein histidine kinase activity
VCSRO45_3020	COG0840	transmembrane signaling receptor activity
VCSRO45_3022	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
VCSRO45_3023	COG2197	response regulator
VCSRO45_3024	COG3850	Histidine kinase
VCSRO45_3025	COG2223	nitrite transmembrane transporter activity
VCSRO45_3026	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
VCSRO45_3027	COG1140	nitrate reductase beta subunit
VCSRO45_3028	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
VCSRO45_3029	COG2181	nitrate reductase activity
VCSRO45_3050	COG1279	arginine transmembrane transporter activity
VCSRO45_3051	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VCSRO45_3052	COG1280	lysine exporter protein (LysE YggA)
VCSRO45_3053	COG3550	peptidyl-serine autophosphorylation
VCSRO45_3060	COG0745	RESPONSE REGULATOR receiver
VCSRO45_3062	COG3623	hexulose-6-phosphate isomerase
VCSRO45_3063	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
VCSRO45_3064	COG0561	phosphatase activity
VCSRO45_3074	COG0745	RESPONSE REGULATOR receiver
VCSRO45_3075	COG5002	protein histidine kinase activity
VCSRO45_3078	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO45_3085	COG1686	Belongs to the peptidase S11 family
VCSRO45_3090	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCSRO45_3090	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCSRO45_3091	COG0509	glycine decarboxylation via glycine cleavage system
VCSRO45_3092	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCSRO45_3094	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VCSRO45_3097	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VCSRO45_3098	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
VCSRO45_3110	COG0454	-acetyltransferase
VCSRO45_3162	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
VCSRO45_3163	COG2944	sequence-specific DNA binding
VCSRO45_3180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO45_3189	COG3549	Plasmid maintenance system killer
VCSRO45_3190	COG3093	addiction module antidote protein HigA
VCSRO45_3194	COG1328	CTP reductase activity
VCSRO45_3195	COG0602	queuosine metabolic process
VCSRO45_3197	COG4067	protein conserved in archaea
VCSRO45_3197	COG0189	ligase activity
VCSRO45_3198	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VCSRO45_3198	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO45_3198	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO45_3199	COG1105	Belongs to the carbohydrate kinase PfkB family
VCSRO45_3200	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO45_3200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO45_3201	COG1609	Transcriptional regulator
VCSRO45_3202	COG0420	3'-5' exonuclease activity
VCSRO45_3203	COG0419	ATPase involved in DNA repair
VCSRO45_3204	COG2205	protein histidine kinase activity
VCSRO45_3204	COG0784	Response regulator, receiver
VCSRO45_3205	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO45_3207	COG0038	chloride channel
VCSRO45_3208	COG0523	cobalamin synthesis protein
VCSRO45_3213	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCSRO45_3215	COG2390	Transcriptional regulator
VCSRO45_3216	COG2897	thiosulfate sulfurtransferase activity
VCSRO45_3218	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCSRO45_3220	COG0302	gtp cyclohydrolase
VCSRO45_3221	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO45_3221	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO45_3222	COG2759	Belongs to the formate--tetrahydrofolate ligase family
VCSRO45_3223	COG1970	mechanosensitive ion channel activity
VCSRO45_3224	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VCSRO45_3227	COG1011	Hydrolase
VCSRO45_3231	COG3833	ABC-type maltose transport systems, permease component
VCSRO45_3232	COG1175	transmembrane transport
VCSRO45_3235	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO45_3237	COG3842	ATPase activity
VCSRO45_3239	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO45_3240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO45_3241	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VCSRO45_3242	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCSRO45_3244	COG3842	ATPase activity
VCSRO45_3245	COG3842	ATPase activity
VCSRO45_3249	COG3104	oligopeptide transport
VCSRO45_3254	COG4166	transmembrane transport
VCSRO45_3255	COG4174	ABC transporter (Permease)
VCSRO45_3256	COG4239	(ABC) transporter, permease
VCSRO45_3257	COG4172	Belongs to the ABC transporter superfamily
VCSRO45_3258	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VCSRO45_3261	COG0625	glutathione transferase activity
VCSRO45_3265	COG2050	protein possibly involved in aromatic compounds catabolism
VCSRO45_3268	COG4771	TonB-dependent receptor
VCSRO45_3268	COG1629	transport
VCSRO45_3269	COG0583	DNA-binding transcription factor activity
VCSRO45_3270	COG0045	succinate-CoA ligase (ADP-forming) activity
VCSRO45_3270	COG1042	CoA-binding domain protein
VCSRO45_3270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO45_3274	COG0023	Translation Initiation Factor
VCSRO45_3276	COG3140	Belongs to the UPF0181 family
VCSRO45_3279	COG0745	RESPONSE REGULATOR receiver
VCSRO45_3281	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VCSRO45_3282	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VCSRO45_3285	COG3706	GGDEF domain
VCSRO45_3289	COG2199	diguanylate cyclase activity
VCSRO45_3295	COG2824	Alkylphosphonate utilization operon protein PhnA
VCSRO45_3299	COG0737	Belongs to the 5'-nucleotidase family
VCSRO45_3300	COG3593	DNA synthesis involved in DNA repair
VCSRO45_3302	COG0583	DNA-binding transcription factor activity
VCSRO45_3303	COG2116	formate transmembrane transporter activity
VCSRO45_3305	COG3038	cytochrome b561
VCSRO45_3307	COG2200	EAL domain
VCSRO45_3309	COG0586	Pfam SNARE associated Golgi protein
VCSRO45_3310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO45_3311	COG0745	RESPONSE REGULATOR receiver
VCSRO45_3312	COG2205	protein histidine kinase activity
VCSRO45_3313	COG0674	pyruvate-flavodoxin oxidoreductase activity
VCSRO45_3313	COG1013	pyruvate-flavodoxin oxidoreductase activity
VCSRO45_3313	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
VCSRO45_3313	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VCSRO45_3314	COG3158	transport of potassium into the cell
VCSRO45_3315	COG0582	viral genome integration into host DNA
VCSRO45_3317	COG3436	PFAM IS66 Orf2 family protein
VCSRO45_3320	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO45_3325	COG2205	protein histidine kinase activity
VCSRO45_3326	COG0745	RESPONSE REGULATOR receiver
VCSRO45_3332	COG2217	Heavy metal translocating P-type atpase
VCSRO45_3333	COG0789	Transcriptional regulator
VCSRO45_3340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO45_3345	COG0583	DNA-binding transcription factor activity
VCSRO45_3354	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCSRO45_3361	COG3385	transposase activity
VCSRO45_3365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO45_3365	COG1263	PTS System
VCSRO45_3366	COG1609	Transcriptional regulator
VCSRO45_3367	COG1621	beta-fructofuranosidase activity
VCSRO45_3368	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO45_3369	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCSRO45_3372	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO45_3373	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO45_3377	COG3069	C4-dicarboxylate transmembrane transporter activity
VCSRO45_3378	COG1760	l-serine dehydratase
VCSRO45_3379	COG2197	response regulator
VCSRO45_3380	COG3850	Histidine kinase
VCSRO45_3381	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCSRO45_3383	COG0243	molybdopterin cofactor binding
VCSRO45_3387	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO45_3388	COG2197	response regulator
VCSRO45_3389	COG3851	Histidine kinase
VCSRO45_3390	COG2271	Major facilitator Superfamily
VCSRO45_3391	COG1840	ABC-type Fe3 transport system, periplasmic component
VCSRO45_3393	COG3842	ATPase activity
VCSRO45_3394	COG3243	poly(R)-hydroxyalkanoic acid synthase
VCSRO45_3396	COG0183	Belongs to the thiolase family
VCSRO45_3397	COG0183	Belongs to the thiolase family
VCSRO45_3400	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO45_3401	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO45_3405	COG3385	transposase activity
VCSRO45_3407	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCSRO45_3409	COG1979	alcohol dehydrogenase
VCSRO45_3412	COG4191	Histidine kinase
VCSRO45_3415	COG2271	Major facilitator Superfamily
VCSRO45_3416	COG0469	pyruvate kinase activity
VCSRO45_3417	COG0784	Response regulator, receiver
VCSRO45_3417	COG2198	Histidine kinase
VCSRO45_3417	COG2205	protein histidine kinase activity
VCSRO45_3418	COG1879	ABC-type sugar transport system periplasmic component
VCSRO45_3419	COG1803	Methylglyoxal synthase
VCSRO45_3420	COG1335	isochorismatase
VCSRO45_3421	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VCSRO45_3422	COG0210	DNA helicase
VCSRO45_3423	COG1289	transmembrane transporter activity
VCSRO45_3430	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
VCSRO45_3431	COG4149	molybdate abc transporter
VCSRO45_3432	COG0725	ABC transporter, periplasmic molybdate-binding protein
VCSRO45_3433	COG1492	cobalamin metabolic process
VCSRO45_3439	COG5002	protein histidine kinase activity
VCSRO45_3439	COG0784	Response regulator, receiver
VCSRO45_3440	COG1879	ABC-type sugar transport system periplasmic component
VCSRO45_3442	COG2827	Endonuclease containing a URI domain
VCSRO45_3443	COG3132	Protein of unknown function, DUF480
VCSRO45_3445	COG2926	Belongs to the UPF0265 family
VCSRO45_3447	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
VCSRO45_3448	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VCSRO45_3449	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCSRO45_3451	COG0247	lactate metabolic process
VCSRO45_3452	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCSRO45_3453	COG3118	belongs to the thioredoxin family
VCSRO45_3458	COG4160	amino acid transport
VCSRO45_3459	COG4215	(ABC) transporter
VCSRO45_3460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO45_3461	COG1126	abc transporter atp-binding protein
VCSRO45_3462	COG3385	transposase activity
VCSRO45_3464	COG2425	protein containing a von Willebrand factor type A (vWA) domain
VCSRO45_3466	COG0494	nUDIX hydrolase
VCSRO45_3467	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VCSRO45_3469	COG1309	transcriptional regulator
VCSRO45_3470	COG0513	Belongs to the DEAD box helicase family
VCSRO45_3471	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
VCSRO45_3473	COG0814	amino acid
VCSRO45_3474	COG0840	transmembrane signaling receptor activity
VCSRO45_3475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VCSRO45_3476	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
VCSRO45_3478	COG1984	allophanate hydrolase subunit 2
VCSRO45_3481	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VCSRO45_3482	COG4181	ATPase activity
VCSRO45_3484	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCSRO45_3485	COG1716	ATPase activity
VCSRO45_3485	COG5001	Diguanylate cyclase
VCSRO45_3487	COG0484	heat shock protein binding
VCSRO45_3491	COG0546	phosphoglycolate phosphatase activity
VCSRO45_3494	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO45_3496	COG0513	Belongs to the DEAD box helicase family
VCSRO45_3499	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCSRO45_3501	COG3046	protein related to deoxyribodipyrimidine photolyase
VCSRO45_3502	COG3397	chitin binding
VCSRO45_3506	COG1166	arginine decarboxylase activity
VCSRO45_3508	COG2239	Acts as a magnesium transporter
VCSRO45_3509	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCSRO45_3510	COG0459	protein refolding
VCSRO45_3512	COG0527	aspartate kinase activity
VCSRO45_3513	COG0662	Cupin 2, conserved barrel domain protein
VCSRO45_3514	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VCSRO45_3515	COG0456	acetyltransferase
VCSRO45_3516	COG2154	pterin-4-alpha-carbinolamine dehydratase
VCSRO45_3517	COG3186	Phenylalanine-4-hydroxylase
VCSRO45_3518	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCSRO45_3521	COG2264	protein methyltransferase activity
VCSRO45_3527	COG1253	flavin adenine dinucleotide binding
VCSRO45_3528	COG1765	OsmC-like protein
VCSRO45_3533	COG0531	amino acid
VCSRO45_3536	COG3279	Response regulator of the LytR AlgR family
VCSRO45_3537	COG3275	phosphorelay sensor kinase activity
VCSRO45_3540	COG0577	efflux transmembrane transporter activity
VCSRO45_3540	COG1136	(ABC) transporter
VCSRO45_3541	COG1136	(ABC) transporter
VCSRO45_3543	COG4989	oxidoreductase activity
VCSRO45_3544	COG0366	Alpha amylase catalytic
VCSRO45_3545	COG2067	long-chain fatty acid transport protein
VCSRO45_3546	COG2267	carboxylic ester hydrolase activity
VCSRO45_3548	COG3227	Zinc metalloprotease (Elastase)
VCSRO45_3549	COG3047	cAMP biosynthetic process
VCSRO45_3551	COG1686	Belongs to the peptidase S11 family
VCSRO45_3552	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VCSRO45_3553	COG1271	oxidase subunit
VCSRO45_3554	COG1271	oxidase subunit
VCSRO45_3555	COG1294	oxidase, subunit
VCSRO45_3558	COG3048	D-serine ammonia-lyase activity
VCSRO45_3559	COG0583	DNA-binding transcription factor activity
VCSRO45_3563	COG1063	alcohol dehydrogenase
VCSRO45_3564	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO45_3565	COG2873	o-acetylhomoserine
VCSRO45_3567	COG0346	lactoylglutathione lyase activity
VCSRO45_3571	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
VCSRO45_3572	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO45_3573	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VCSRO45_3574	COG0363	glucosamine-6-phosphate deaminase activity
VCSRO45_3575	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VCSRO45_3580	COG1929	Belongs to the glycerate kinase type-1 family
VCSRO45_3582	COG0748	coenzyme F420 binding
VCSRO45_3583	COG3721	Heme iron utilization protein
VCSRO45_3585	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCSRO45_3586	COG0811	peptide transport
VCSRO45_3587	COG0848	biopolymer transport protein
VCSRO45_3588	COG4558	Periplasmic binding protein
VCSRO45_3589	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO45_3590	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VCSRO45_3598	COG0633	Ferredoxin
VCSRO45_3598	COG3217	Mosc domain protein beta barrel domain protein
VCSRO45_3598	COG3217	Mosc domain protein beta barrel domain protein
VCSRO45_3598	COG0633	Ferredoxin
VCSRO45_3599	COG0418	dihydroorotase activity
VCSRO45_3601	COG3152	Membrane
VCSRO45_3603	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCSRO45_3604	COG2354	Protein conserved in bacteria
VCSRO45_3605	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO45_3606	COG1278	Cold shock
VCSRO45_3611	COG2199	diguanylate cyclase activity
VCSRO45_3612	COG2199	diguanylate cyclase activity
VCSRO45_3613	COG1349	DNA-binding transcription factor activity
VCSRO45_3616	COG3833	ABC-type maltose transport systems, permease component
VCSRO45_3617	COG1175	transmembrane transport
VCSRO45_3619	COG3842	ATPase activity
VCSRO45_3620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO45_3623	COG0393	Putative heavy-metal-binding
VCSRO45_3625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO45_3626	COG0784	Response regulator, receiver
VCSRO45_3626	COG0835	chemotaxis
VCSRO45_3627	COG1846	Transcriptional regulator
VCSRO45_3628	COG3706	GGDEF domain
VCSRO45_3635	COG0583	DNA-binding transcription factor activity
VCSRO45_3636	COG5001	Diguanylate cyclase
VCSRO45_3638	COG1741	Belongs to the pirin family
VCSRO45_3639	COG3123	guanosine phosphorylase activity
VCSRO45_3641	COG2211	Major facilitator Superfamily
VCSRO45_3644	COG1067	ATP-dependent peptidase activity
VCSRO45_3646	COG4172	Belongs to the ABC transporter superfamily
VCSRO45_3650	COG0583	DNA-binding transcription factor activity
VCSRO45_3651	COG1620	l-lactate permease
VCSRO45_3654	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
VCSRO45_3656	COG0840	transmembrane signaling receptor activity
VCSRO45_3658	COG0513	Belongs to the DEAD box helicase family
VCSRO45_3660	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
VCSRO45_3662	COG1132	(ABC) transporter
VCSRO45_3664	COG1902	pentaerythritol trinitrate reductase activity
VCSRO45_3666	COG1280	lysine exporter protein (LysE YggA)
VCSRO45_3667	COG2207	Transcriptional regulator
VCSRO45_3671	COG1846	Transcriptional regulator
VCSRO45_3672	COG1764	response to oxidative stress
VCSRO45_3673	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCSRO45_3674	COG0697	spore germination
VCSRO45_3676	COG0700	Nucleoside recognition
VCSRO45_3677	COG3366	ferrous iron transmembrane transporter activity
VCSRO45_3678	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
VCSRO45_3680	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VCSRO45_3681	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
VCSRO45_3682	COG2259	Doxx family
VCSRO45_3687	COG0363	glucosamine-6-phosphate deaminase activity
VCSRO45_3690	COG4580	involved in the transport of maltose and maltodextrins
VCSRO45_3693	COG0840	transmembrane signaling receptor activity
VCSRO45_3695	COG0840	transmembrane signaling receptor activity
VCSRO45_3697	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO45_3698	COG1126	abc transporter atp-binding protein
VCSRO45_3700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO45_3701	COG4597	amino acid ABC transporter
VCSRO45_3702	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCSRO45_3703	COG2213	PTS system mannitol-specific
VCSRO45_3703	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO45_3704	COG0246	Mannitol dehydrogenase
VCSRO45_3705	COG3722	fumarate hydratase activity
VCSRO45_3706	COG0673	inositol 2-dehydrogenase activity
VCSRO45_3712	COG2910	NAD(P)H-binding
VCSRO45_3714	COG0840	transmembrane signaling receptor activity
VCSRO45_3715	COG4221	oxidoreductase activity
VCSRO45_3717	COG1901	pseudouridine methyltransferase
VCSRO45_3719	COG0531	amino acid
VCSRO45_3720	COG1982	Orn Lys Arg decarboxylase major
VCSRO45_3725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCSRO45_3730	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VCSRO45_3738	COG0745	RESPONSE REGULATOR receiver
VCSRO45_3742	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
VCSRO45_3743	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCSRO45_3744	COG0840	transmembrane signaling receptor activity
VCSRO45_3745	COG0835	chemotaxis
VCSRO45_3746	COG0835	chemotaxis
VCSRO45_3747	COG0643	Histidine kinase
VCSRO45_3747	COG2198	Histidine kinase
VCSRO45_3751	COG0601	transmembrane transport
VCSRO45_3752	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO45_3754	COG2194	sulfuric ester hydrolase activity
VCSRO45_3755	COG0642	Histidine kinase
VCSRO45_3758	COG4221	oxidoreductase activity
VCSRO45_3762	COG1444	tRNA N-acetyltransferase activity
VCSRO45_3763	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine