locus-tag	class	description
VCSRO51_0001	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCSRO51_0002	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
VCSRO51_0003	COG0706	membrane insertase activity
VCSRO51_0004	COG0594	ribonuclease P activity
VCSRO51_0005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VCSRO51_0006	COG1126	abc transporter atp-binding protein
VCSRO51_0009	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VCSRO51_0010	COG0592	DNA-directed DNA polymerase activity
VCSRO51_0011	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VCSRO51_0012	COG0187	DNA topoisomerase II activity
VCSRO51_0015	COG0071	Belongs to the small heat shock protein (HSP20) family
VCSRO51_0016	COG3977	Valine--pyruvate aminotransferase
VCSRO51_0017	COG0751	glycine-tRNA ligase activity
VCSRO51_0018	COG0752	glycyl-tRNA synthetase alpha subunit
VCSRO51_0019	COG2119	membrane
VCSRO51_0021	COG0425	Belongs to the sulfur carrier protein TusA family
VCSRO51_0023	COG0604	alcohol dehydrogenase
VCSRO51_0025	COG0129	dihydroxy-acid dehydratase activity
VCSRO51_0026	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCSRO51_0029	COG0606	chelatase, subunit chli
VCSRO51_0030	COG0204	Acyl-transferase
VCSRO51_0031	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCSRO51_0032	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VCSRO51_0034	COG3084	Protein conserved in bacteria
VCSRO51_0035	COG4326	sporulation control protein
VCSRO51_0036	COG1272	protein, Hemolysin III
VCSRO51_0038	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCSRO51_0039	COG0569	domain protein
VCSRO51_0040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VCSRO51_0040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCSRO51_0041	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VCSRO51_0042	COG0242	peptide deformylase activity
VCSRO51_0043	COG1652	LysM domain
VCSRO51_0044	COG0758	DNA mediated transformation
VCSRO51_0045	COG2922	Belongs to the Smg family
VCSRO51_0046	COG0551	DNA topoisomerase type I activity
VCSRO51_0047	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VCSRO51_0048	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VCSRO51_0049	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO51_0050	COG0408	coproporphyrinogen oxidase activity
VCSRO51_0051	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VCSRO51_0053	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VCSRO51_0060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VCSRO51_0061	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VCSRO51_0063	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCSRO51_0064	COG2104	thiamine diphosphate biosynthetic process
VCSRO51_0065	COG2022	thiamine diphosphate biosynthetic process
VCSRO51_0066	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCSRO51_0067	COG2801	Transposase and inactivated derivatives
VCSRO51_0069	COG0006	proline dipeptidase activity
VCSRO51_0069	COG0006	proline dipeptidase activity
VCSRO51_0073	COG1522	sequence-specific DNA binding
VCSRO51_0074	COG5001	Diguanylate cyclase
VCSRO51_0074	COG5002	protein histidine kinase activity
VCSRO51_0078	COG0589	response to stress
VCSRO51_0079	COG1528	Iron-storage protein
VCSRO51_0081	COG2081	HI0933 family
VCSRO51_0084	COG1322	Protein conserved in bacteria
VCSRO51_0085	COG2226	methyltransferase
VCSRO51_0088	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO51_0089	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO51_0090	COG0805	protein transport
VCSRO51_0091	COG1858	cytochrome C peroxidase
VCSRO51_0092	COG0534	Mate efflux family protein
VCSRO51_0094	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VCSRO51_0095	COG2937	Belongs to the GPAT DAPAT family
VCSRO51_0096	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VCSRO51_0097	COG3161	chorismate lyase activity
VCSRO51_0098	COG1580	Controls the rotational direction of flagella during chemotaxis
VCSRO51_0099	COG0840	transmembrane signaling receptor activity
VCSRO51_0101	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO51_0102	COG0084	hydrolase, TatD family'
VCSRO51_0105	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO51_0105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO51_0109	COG3078	GTPase activator activity
VCSRO51_0112	COG3071	HemY protein
VCSRO51_0113	COG2959	enzyme of heme biosynthesis
VCSRO51_0114	COG1587	Uroporphyrinogen-III synthase
VCSRO51_0115	COG0181	hydroxymethylbilane synthase activity
VCSRO51_0117	COG1965	Belongs to the frataxin family
VCSRO51_0118	COG0019	diaminopimelate decarboxylase activity
VCSRO51_0119	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VCSRO51_0121	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VCSRO51_0122	COG1011	Hydrolase
VCSRO51_0123	COG2200	EAL domain
VCSRO51_0123	COG2199	diguanylate cyclase activity
VCSRO51_0123	COG3287	FIST C domain
VCSRO51_0126	COG0561	phosphatase activity
VCSRO51_0127	COG2267	carboxylic ester hydrolase activity
VCSRO51_0128	COG1280	lysine exporter protein (LysE YggA)
VCSRO51_0129	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCSRO51_0130	COG0783	Belongs to the Dps family
VCSRO51_0134	COG2801	Transposase and inactivated derivatives
VCSRO51_0137	COG0742	ribosomal rna small subunit methyltransferase
VCSRO51_0138	COG0552	protein localization to endoplasmic reticulum
VCSRO51_0139	COG2884	Cell division ATP-binding protein ftsE
VCSRO51_0140	COG2177	Part of the ABC transporter FtsEX involved in
VCSRO51_0141	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCSRO51_0142	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO51_0145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCSRO51_0149	COG1404	Belongs to the peptidase S8 family
VCSRO51_0150	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
VCSRO51_0164	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VCSRO51_0165	COG3300	MHYT domain
VCSRO51_0165	COG5001	Diguanylate cyclase
VCSRO51_0167	COG3852	Histidine kinase
VCSRO51_0169	COG0174	glutamine synthetase
VCSRO51_0171	COG1217	gtp-binding protein TYPA
VCSRO51_0173	COG1295	ribonuclease BN
VCSRO51_0174	COG1490	D-aminoacyl-tRNA deacylase activity
VCSRO51_0175	COG0456	acetyltransferase
VCSRO51_0177	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
VCSRO51_0178	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VCSRO51_0179	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VCSRO51_0180	COG3031	protein transport across the cell outer membrane
VCSRO51_0182	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO51_0183	COG1459	type II secretion system
VCSRO51_0184	COG2165	general secretion pathway protein
VCSRO51_0185	COG2165	general secretion pathway protein
VCSRO51_0186	COG2165	general secretion pathway protein
VCSRO51_0187	COG4795	General secretion pathway protein
VCSRO51_0188	COG3156	type II secretion system protein K
VCSRO51_0189	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCSRO51_0190	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCSRO51_0192	COG1218	3'(2'),5'-bisphosphate nucleotidase
VCSRO51_0193	COG0494	nUDIX hydrolase
VCSRO51_0195	COG1040	competence protein
VCSRO51_0196	COG0596	Alpha beta hydrolase
VCSRO51_0198	COG2183	response to ionizing radiation
VCSRO51_0199	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO51_0204	COG1129	ABC transporter
VCSRO51_0205	COG1172	Belongs to the binding-protein-dependent transport system permease family
VCSRO51_0206	COG1472	Belongs to the glycosyl hydrolase 3 family
VCSRO51_0210	COG2233	PERMEase
VCSRO51_0211	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VCSRO51_0212	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCSRO51_0213	COG1758	RNA polymerase activity
VCSRO51_0214	COG0194	GDP metabolic process
VCSRO51_0215	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VCSRO51_0216	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCSRO51_0220	COG4232	protein-disulfide reductase activity
VCSRO51_0222	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCSRO51_0223	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCSRO51_0224	COG1027	Aspartate ammonia-lyase
VCSRO51_0225	COG3706	GGDEF domain
VCSRO51_0226	COG3030	protein affecting phage T7 exclusion by the F plasmid
VCSRO51_0227	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VCSRO51_0229	COG2205	protein histidine kinase activity
VCSRO51_0230	COG0745	RESPONSE REGULATOR receiver
VCSRO51_0232	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VCSRO51_0233	COG0205	6-phosphofructokinase activity
VCSRO51_0234	COG1494	fructose-1,6-bisphosphatase
VCSRO51_0235	COG3074	FtsZ-dependent cytokinesis
VCSRO51_0236	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VCSRO51_0237	COG0527	aspartate kinase activity
VCSRO51_0237	COG0460	homoserine dehydrogenase
VCSRO51_0238	COG0626	cystathionine gamma-synthase activity
VCSRO51_0239	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
VCSRO51_0240	COG0281	malic enzyme
VCSRO51_0241	COG0254	rRNA binding
VCSRO51_0242	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VCSRO51_0243	COG1609	Transcriptional regulator
VCSRO51_0244	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCSRO51_0245	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VCSRO51_0246	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VCSRO51_0247	COG1575	Belongs to the MenA family. Type 1 subfamily
VCSRO51_0248	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCSRO51_0249	COG0534	Mate efflux family protein
VCSRO51_0250	COG0149	triose-phosphate isomerase activity
VCSRO51_0255	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCSRO51_0256	COG0459	protein refolding
VCSRO51_0261	COG1509	lysine 2,3-aminomutase activity
VCSRO51_0262	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCSRO51_0264	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VCSRO51_0265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VCSRO51_0266	COG1053	succinate dehydrogenase
VCSRO51_0267	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VCSRO51_0268	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO51_0269	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VCSRO51_0270	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VCSRO51_0271	COG1045	serine acetyltransferase
VCSRO51_0273	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VCSRO51_0274	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VCSRO51_0275	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VCSRO51_0276	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCSRO51_0277	COG0137	argininosuccinate synthase activity
VCSRO51_0278	COG0165	Argininosuccinate lyase
VCSRO51_0280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO51_0281	COG0678	peroxiredoxin activity
VCSRO51_0281	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCSRO51_0283	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VCSRO51_0289	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VCSRO51_0290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VCSRO51_0291	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VCSRO51_0293	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VCSRO51_0294	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VCSRO51_0295	COG0546	phosphoglycolate phosphatase activity
VCSRO51_0296	COG0180	Tryptophanyl-tRNA synthetase
VCSRO51_0299	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCSRO51_0301	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VCSRO51_0306	COG2801	Transposase and inactivated derivatives
VCSRO51_0308	COG3954	Phosphoribulokinase
VCSRO51_0310	COG0429	hydrolase of the alpha beta-hydrolase fold
VCSRO51_0312	COG0488	(ABC) transporter
VCSRO51_0313	COG2249	NAD(P)H dehydrogenase (quinone) activity
VCSRO51_0316	COG1047	Peptidyl-prolyl cis-trans
VCSRO51_0318	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VCSRO51_0319	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VCSRO51_0320	COG3083	sulfuric ester hydrolase activity
VCSRO51_0321	COG0557	exoribonuclease II activity
VCSRO51_0322	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCSRO51_0323	COG0051	transcription antitermination factor activity, RNA binding
VCSRO51_0324	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VCSRO51_0325	COG0088	Forms part of the polypeptide exit tunnel
VCSRO51_0326	COG0089	rRNA binding
VCSRO51_0327	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VCSRO51_0328	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VCSRO51_0329	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VCSRO51_0330	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VCSRO51_0331	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VCSRO51_0332	COG0255	Belongs to the universal ribosomal protein uL29 family
VCSRO51_0333	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VCSRO51_0334	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VCSRO51_0335	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VCSRO51_0336	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VCSRO51_0337	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VCSRO51_0338	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VCSRO51_0340	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VCSRO51_0341	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VCSRO51_0342	COG1841	ribosomal large subunit assembly
VCSRO51_0344	COG0201	protein transport
VCSRO51_0345	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCSRO51_0346	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VCSRO51_0347	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VCSRO51_0348	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VCSRO51_0349	COG0202	RNA polymerase activity
VCSRO51_0350	COG0203	ribosomal protein L17
VCSRO51_0352	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO51_0353	COG3061	Opacity-associated protein A
VCSRO51_0353	COG3266	domain, Protein
VCSRO51_0354	COG0697	spore germination
VCSRO51_0355	COG2153	protein acetylation
VCSRO51_0356	COG0513	Belongs to the DEAD box helicase family
VCSRO51_0358	COG0737	Belongs to the 5'-nucleotidase family
VCSRO51_0359	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VCSRO51_0359	COG1648	precorrin-2 dehydrogenase activity
VCSRO51_0360	COG0175	sulfate reduction
VCSRO51_0361	COG2895	sulfate adenylyltransferase (ATP) activity
VCSRO51_0362	COG0529	Catalyzes the synthesis of activated sulfate
VCSRO51_0366	COG0577	efflux transmembrane transporter activity
VCSRO51_0366	COG1136	(ABC) transporter
VCSRO51_0369	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VCSRO51_0370	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO51_0371	COG0729	surface antigen
VCSRO51_0372	COG2911	Protein conserved in bacteria
VCSRO51_0373	COG2105	PFAM AIG2 family protein
VCSRO51_0374	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VCSRO51_0376	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCSRO51_0377	COG0163	prenyltransferase activity
VCSRO51_0379	COG1178	ABC-type Fe3 transport system permease component
VCSRO51_0380	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VCSRO51_0381	COG3028	Belongs to the UPF0307 family
VCSRO51_0382	COG0312	modulator of DNA gyrase
VCSRO51_0383	COG2239	Acts as a magnesium transporter
VCSRO51_0384	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO51_0385	COG1660	Displays ATPase and GTPase activities
VCSRO51_0386	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO51_0387	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCSRO51_0389	COG1137	ATPase activity
VCSRO51_0390	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VCSRO51_0393	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VCSRO51_0393	COG0517	IMP dehydrogenase activity
VCSRO51_0395	COG1127	ABC transporter
VCSRO51_0396	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VCSRO51_0397	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCSRO51_0398	COG2854	intermembrane phospholipid transfer
VCSRO51_0400	COG5007	Belongs to the BolA IbaG family
VCSRO51_0401	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VCSRO51_0402	COG0204	Acyl-transferase
VCSRO51_0403	COG0251	oxidation-reduction process
VCSRO51_0405	COG0540	Belongs to the ATCase OTCase family
VCSRO51_0407	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VCSRO51_0408	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VCSRO51_0409	COG0564	pseudouridine synthase activity
VCSRO51_0410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCSRO51_0411	COG0525	valine-tRNA ligase activity
VCSRO51_0412	COG2927	DNA polymerase III (CHI subunit)
VCSRO51_0413	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCSRO51_0414	COG0795	lipopolysaccharide-transporting ATPase activity
VCSRO51_0415	COG0795	lipopolysaccharide-transporting ATPase activity
VCSRO51_0418	COG3437	response regulator, receiver
VCSRO51_0427	COG0066	3-isopropylmalate dehydratase activity
VCSRO51_0428	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
VCSRO51_0429	COG0473	3-isopropylmalate dehydrogenase activity
VCSRO51_0434	COG0583	DNA-binding transcription factor activity
VCSRO51_0435	COG1022	Amp-dependent synthetase and ligase
VCSRO51_0436	COG0028	Belongs to the TPP enzyme family
VCSRO51_0437	COG0440	acetolactate synthase activity
VCSRO51_0438	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO51_0439	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VCSRO51_0440	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VCSRO51_0441	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VCSRO51_0442	COG3079	Belongs to the UPF0149 family
VCSRO51_0443	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO51_0444	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO51_0447	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VCSRO51_0449	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VCSRO51_0450	COG1595	DNA-templated transcription, initiation
VCSRO51_0453	COG3086	response to oxidative stress
VCSRO51_0454	COG0481	GTPase activity
VCSRO51_0456	COG0571	ribonuclease III activity
VCSRO51_0457	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VCSRO51_0458	COG1381	Involved in DNA repair and RecF pathway recombination
VCSRO51_0459	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VCSRO51_0460	COG0736	holo-[acyl-carrier-protein] synthase activity
VCSRO51_0464	COG5001	Diguanylate cyclase
VCSRO51_0466	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCSRO51_0467	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCSRO51_0468	COG3956	TIGRFAM MazG family protein
VCSRO51_0469	COG0504	CTP synthase activity
VCSRO51_0470	COG0148	phosphopyruvate hydratase activity
VCSRO51_0471	COG0617	tRNA 3'-terminal CCA addition
VCSRO51_0472	COG3267	Type II secretory pathway component ExeA
VCSRO51_0472	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO51_0474	COG4991	sh3 domain protein
VCSRO51_0475	COG0306	phosphate transporter
VCSRO51_0476	COG1392	Phosphate transport regulator
VCSRO51_0477	COG3025	triphosphatase activity
VCSRO51_0479	COG0840	transmembrane signaling receptor activity
VCSRO51_0480	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VCSRO51_0482	COG1538	Outer membrane efflux protein
VCSRO51_0483	COG0494	nUDIX hydrolase
VCSRO51_0484	COG3151	Protein conserved in bacteria
VCSRO51_0486	COG3150	esterase
VCSRO51_0487	COG0187	DNA topoisomerase II activity
VCSRO51_0488	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VCSRO51_0490	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VCSRO51_0491	COG0237	dephospho-CoA kinase activity
VCSRO51_0493	COG1459	type II secretion system
VCSRO51_0494	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO51_0498	COG0716	FMN binding
VCSRO51_0499	COG4974	Belongs to the 'phage' integrase family
VCSRO51_0500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCSRO51_0501	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VCSRO51_0502	COG0737	Belongs to the 5'-nucleotidase family
VCSRO51_0503	COG2186	Transcriptional regulator
VCSRO51_0504	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VCSRO51_0505	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCSRO51_0506	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO51_0508	COG3116	cell division
VCSRO51_0509	COG0768	penicillin binding
VCSRO51_0510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VCSRO51_0511	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VCSRO51_0513	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VCSRO51_0514	COG0772	Belongs to the SEDS family
VCSRO51_0516	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCSRO51_0517	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VCSRO51_0518	COG0849	cell division
VCSRO51_0519	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VCSRO51_0520	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VCSRO51_0522	COG0653	protein targeting
VCSRO51_0523	COG0494	nUDIX hydrolase
VCSRO51_0524	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
VCSRO51_0525	COG0505	Belongs to the CarA family
VCSRO51_0526	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VCSRO51_0530	COG0730	response to heat
VCSRO51_0531	COG0583	DNA-binding transcription factor activity
VCSRO51_0532	COG2860	membrane
VCSRO51_0533	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VCSRO51_0535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VCSRO51_0537	COG0493	'glutamate synthase
VCSRO51_0538	COG0067	glutamate synthase
VCSRO51_0538	COG0069	glutamate synthase activity
VCSRO51_0538	COG0070	glutamate synthase
VCSRO51_0540	COG0070	glutamate synthase
VCSRO51_0540	COG0067	glutamate synthase
VCSRO51_0540	COG0069	glutamate synthase activity
VCSRO51_0541	COG1242	4 iron, 4 sulfur cluster binding
VCSRO51_0542	COG3706	GGDEF domain
VCSRO51_0542	COG4251	negative regulation of phosphorylation
VCSRO51_0542	COG5001	Diguanylate cyclase
VCSRO51_0542	COG2203	Gaf domain
VCSRO51_0543	COG0784	Response regulator, receiver
VCSRO51_0543	COG2198	Histidine kinase
VCSRO51_0543	COG5002	protein histidine kinase activity
VCSRO51_0544	COG0745	RESPONSE REGULATOR receiver
VCSRO51_0546	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCSRO51_0549	COG0083	homoserine kinase activity
VCSRO51_0550	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VCSRO51_0551	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VCSRO51_0552	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VCSRO51_0553	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VCSRO51_0556	COG1115	amino acid carrier protein
VCSRO51_0557	COG3022	response to hydroperoxide
VCSRO51_0559	COG0084	hydrolase, TatD family'
VCSRO51_0560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO51_0561	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO51_0562	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VCSRO51_0563	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO51_0564	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VCSRO51_0565	COG0813	purine-nucleoside phosphorylase activity
VCSRO51_0567	COG0560	Phosphoserine phosphatase
VCSRO51_0569	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VCSRO51_0570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCSRO51_0571	COG1022	Amp-dependent synthetase and ligase
VCSRO51_0574	COG3250	beta-galactosidase activity
VCSRO51_0575	COG1609	Transcriptional regulator
VCSRO51_0576	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO51_0579	COG0569	domain protein
VCSRO51_0579	COG0189	ligase activity
VCSRO51_0581	COG0456	acetyltransferase
VCSRO51_0583	COG2171	N-acyltransferase activity
VCSRO51_0584	COG3141	response to X-ray
VCSRO51_0587	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VCSRO51_0588	COG1074	ATP-dependent DNA helicase activity
VCSRO51_0589	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VCSRO51_0591	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VCSRO51_0591	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCSRO51_0593	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VCSRO51_0594	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VCSRO51_0595	COG2166	iron-sulfur cluster assembly
VCSRO51_0596	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCSRO51_0597	COG0693	protein deglycase activity
VCSRO51_0598	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VCSRO51_0599	COG3248	Nucleoside-binding outer membrane protein
VCSRO51_0601	COG1595	DNA-templated transcription, initiation
VCSRO51_0603	COG2211	Major facilitator Superfamily
VCSRO51_0604	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCSRO51_0606	COG2813	Specifically methylates the guanine in position
VCSRO51_0607	COG0271	Belongs to the BolA IbaG family
VCSRO51_0608	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO51_0609	COG1805	sodium ion transport
VCSRO51_0610	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO51_0611	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO51_0612	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO51_0613	COG2871	sodium ion transport
VCSRO51_0614	COG1477	protein flavinylation
VCSRO51_0618	COG3706	GGDEF domain
VCSRO51_0619	COG0733	neurotransmitter:sodium symporter activity
VCSRO51_0620	COG3385	transposase activity
VCSRO51_0622	COG0189	ligase activity
VCSRO51_0623	COG4067	protein conserved in archaea
VCSRO51_0623	COG0189	ligase activity
VCSRO51_0624	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO51_0625	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO51_0626	COG2252	PERMEase
VCSRO51_0627	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VCSRO51_0628	COG1073	alpha beta
VCSRO51_0630	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VCSRO51_0631	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VCSRO51_0632	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VCSRO51_0633	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO51_0633	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO51_0636	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VCSRO51_0637	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCSRO51_0638	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VCSRO51_0639	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VCSRO51_0641	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VCSRO51_0642	COG0024	Methionine aminopeptidase
VCSRO51_0643	COG0052	Belongs to the universal ribosomal protein uS2 family
VCSRO51_0644	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VCSRO51_0645	COG0528	UMP kinase activity
VCSRO51_0646	COG0233	cytoplasmic translational termination
VCSRO51_0647	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VCSRO51_0648	COG0575	Belongs to the CDS family
VCSRO51_0649	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VCSRO51_0650	COG0750	zinc metalloprotease
VCSRO51_0652	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VCSRO51_0653	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO51_0654	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCSRO51_0655	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO51_0656	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO51_0657	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
VCSRO51_0658	COG0587	DNA-directed DNA polymerase activity
VCSRO51_0659	COG0825	malonyl-CoA metabolic process
VCSRO51_0660	COG0037	tRNA processing
VCSRO51_0662	COG3479	Phenolic acid decarboxylase
VCSRO51_0663	COG0347	Belongs to the P(II) protein family
VCSRO51_0664	COG3021	interspecies interaction between organisms
VCSRO51_0665	COG0741	lytic transglycosylase activity
VCSRO51_0665	COG1388	LysM domain
VCSRO51_0666	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCSRO51_0667	COG2226	methyltransferase
VCSRO51_0668	COG0328	RNA-DNA hybrid ribonuclease activity
VCSRO51_0671	COG1960	acyl-CoA dehydrogenase activity
VCSRO51_0672	COG1960	acyl-CoA dehydrogenase activity
VCSRO51_0673	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCSRO51_0674	COG0121	glutamine amidotransferase
VCSRO51_0675	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VCSRO51_0676	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VCSRO51_0677	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VCSRO51_0679	COG1187	pseudouridine synthase activity
VCSRO51_0680	COG2840	Smr protein MutS2
VCSRO51_0683	COG3735	TraB family
VCSRO51_0686	COG2217	Heavy metal translocating P-type atpase
VCSRO51_0686	COG2608	mercury ion transmembrane transporter activity
VCSRO51_0687	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCSRO51_0690	COG1629	transport
VCSRO51_0690	COG4774	siderophore transport
VCSRO51_0691	COG2375	cellular response to nickel ion
VCSRO51_0692	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCSRO51_0692	COG2226	methyltransferase
VCSRO51_0692	COG3433	isochorismatase activity
VCSRO51_0699	COG0784	Response regulator, receiver
VCSRO51_0699	COG0835	chemotaxis
VCSRO51_0700	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCSRO51_0701	COG1815	bacterial-type flagellum-dependent cell motility
VCSRO51_0704	COG1749	Flagellar hook protein flgE
VCSRO51_0705	COG4787	bacterial-type flagellum-dependent cell motility
VCSRO51_0707	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VCSRO51_0708	COG1706	bacterial-type flagellum-dependent cell motility
VCSRO51_0709	COG1705	Flagellar rod assembly protein muramidase FlgJ
VCSRO51_0709	COG3951	Flagellar rod assembly protein muramidase FlgJ
VCSRO51_0712	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO51_0713	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO51_0728	COG0012	GTP binding
VCSRO51_0729	COG0193	aminoacyl-tRNA hydrolase activity
VCSRO51_0730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VCSRO51_0731	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VCSRO51_0732	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VCSRO51_0733	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VCSRO51_0734	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VCSRO51_0735	COG2890	protein-(glutamine-N5) methyltransferase activity
VCSRO51_0737	COG2912	Transglutaminase-like superfamily
VCSRO51_0738	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VCSRO51_0739	COG0737	Belongs to the 5'-nucleotidase family
VCSRO51_0740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VCSRO51_0741	COG2233	PERMEase
VCSRO51_0743	COG3385	transposase activity
VCSRO51_0747	COG1393	Belongs to the ArsC family
VCSRO51_0748	COG4783	chaperone-mediated protein folding
VCSRO51_0752	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VCSRO51_0755	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VCSRO51_0757	COG1876	peptidase activity
VCSRO51_0759	COG1393	Belongs to the ArsC family
VCSRO51_0763	COG2837	iron assimilation
VCSRO51_0764	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO51_0765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO51_0766	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO51_0767	COG1334	flagellar protein FlaG
VCSRO51_0768	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VCSRO51_0770	COG1516	flagellar protein fliS
VCSRO51_0774	COG1677	Flagellar hook-basal body complex protein FliE
VCSRO51_0776	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VCSRO51_0777	COG1317	bacterial-type flagellum organization
VCSRO51_0781	COG1580	Controls the rotational direction of flagella during chemotaxis
VCSRO51_0786	COG1987	bacterial-type flagellum assembly
VCSRO51_0787	COG1684	flagellar biosynthetic protein fliR
VCSRO51_0789	COG2840	Smr protein MutS2
VCSRO51_0790	COG2890	protein-(glutamine-N5) methyltransferase activity
VCSRO51_0791	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VCSRO51_0792	COG2860	membrane
VCSRO51_0793	COG3101	peptidyl-lysine hydroxylation
VCSRO51_0796	COG0431	NADPH-dependent FMN reductase
VCSRO51_0798	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCSRO51_0799	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO51_0800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCSRO51_0801	COG0735	belongs to the Fur family
VCSRO51_0803	COG0583	DNA-binding transcription factor activity
VCSRO51_0805	COG1346	cytolysis
VCSRO51_0808	COG0596	Alpha beta hydrolase
VCSRO51_0809	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VCSRO51_0810	COG0033	Phosphoglucomutase
VCSRO51_0812	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VCSRO51_0813	COG0372	Belongs to the citrate synthase family
VCSRO51_0814	COG2009	succinate dehydrogenase
VCSRO51_0815	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VCSRO51_0816	COG1053	succinate dehydrogenase
VCSRO51_0818	COG0567	Dehydrogenase, E1 component
VCSRO51_0819	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCSRO51_0820	COG0045	succinate-CoA ligase (ADP-forming) activity
VCSRO51_0822	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VCSRO51_0823	COG1121	(ABC) transporter
VCSRO51_0824	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VCSRO51_0825	COG4977	sequence-specific DNA binding
VCSRO51_0826	COG1918	ferrous iron import across plasma membrane
VCSRO51_0830	COG0018	arginyl-trna synthetase
VCSRO51_0832	COG1025	Belongs to the peptidase M16 family
VCSRO51_0833	COG2062	phosphohistidine phosphatase, SixA
VCSRO51_0839	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VCSRO51_0840	COG0784	Response regulator, receiver
VCSRO51_0840	COG0643	Histidine kinase
VCSRO51_0840	COG2198	Histidine kinase
VCSRO51_0841	COG2201	protein-glutamate methylesterase activity
VCSRO51_0842	COG1192	Involved in chromosome partitioning
VCSRO51_0844	COG0835	chemotaxis
VCSRO51_0846	COG4133	protoheme IX ABC transporter activity
VCSRO51_0847	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCSRO51_0848	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCSRO51_0850	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VCSRO51_0851	COG1138	Cytochrome C-type biogenesis protein
VCSRO51_0852	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VCSRO51_0853	COG3088	subunit of a heme lyase
VCSRO51_0853	COG4235	cytochrome complex assembly
VCSRO51_0855	COG2853	Lipoprotein
VCSRO51_0859	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VCSRO51_0860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCSRO51_0861	COG0123	including yeast histone deacetylase and acetoin utilization protein
VCSRO51_0864	COG3083	sulfuric ester hydrolase activity
VCSRO51_0865	COG3082	Protein of unknown function (DUF1414)
VCSRO51_0866	COG3081	Nucleoid-associated protein
VCSRO51_0868	COG1757	Na H antiporter
VCSRO51_0869	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCSRO51_0870	COG2095	MarC family integral membrane protein
VCSRO51_0871	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO51_0871	COG1454	alcohol dehydrogenase
VCSRO51_0873	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO51_0874	COG1530	ribonuclease E activity
VCSRO51_0875	COG0564	pseudouridine synthase activity
VCSRO51_0876	COG0424	maF-like protein
VCSRO51_0877	COG1399	metal-binding, possibly nucleic acid-binding protein
VCSRO51_0878	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VCSRO51_0879	COG0416	fatty acid biosynthetic process
VCSRO51_0880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCSRO51_0882	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO51_0883	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VCSRO51_0884	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCSRO51_0885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCSRO51_0886	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VCSRO51_0887	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VCSRO51_0889	COG0084	hydrolase, TatD family'
VCSRO51_0890	COG1263	PTS System
VCSRO51_0890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO51_0892	COG0733	neurotransmitter:sodium symporter activity
VCSRO51_0895	COG4667	esterase of the alpha-beta hydrolase superfamily
VCSRO51_0897	COG1940	carbohydrate kinase activity
VCSRO51_0898	COG0784	Response regulator, receiver
VCSRO51_0898	COG0835	chemotaxis
VCSRO51_0902	COG3423	Transcriptional regulator
VCSRO51_0904	COG2842	Transposition protein
VCSRO51_0924	COG3772	lysozyme
VCSRO51_0954	COG2226	methyltransferase
VCSRO51_0956	COG0676	glucose-6-phosphate 1-epimerase activity
VCSRO51_0957	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO51_0958	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO51_0960	COG3139	Protein of unknown function (DUF1315)
VCSRO51_0961	COG0252	asparaginase activity
VCSRO51_0962	COG0616	signal peptide processing
VCSRO51_0963	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCSRO51_0963	COG1902	pentaerythritol trinitrate reductase activity
VCSRO51_0964	COG0788	formyltetrahydrofolate deformylase activity
VCSRO51_0966	COG1199	ATP-dependent helicase activity
VCSRO51_0967	COG1214	PFAM Peptidase M22, glycoprotease
VCSRO51_0970	COG0596	Alpha beta hydrolase
VCSRO51_0971	COG0318	PFAM AMP-dependent synthetase and ligase
VCSRO51_0972	COG0318	PFAM AMP-dependent synthetase and ligase
VCSRO51_0973	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VCSRO51_0976	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VCSRO51_0977	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VCSRO51_0978	COG0436	Aminotransferase
VCSRO51_0979	COG1169	isochorismate synthase
VCSRO51_0980	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VCSRO51_0981	COG0596	Alpha beta hydrolase
VCSRO51_0985	COG3135	benzoate transporter
VCSRO51_0986	COG1396	sequence-specific DNA binding
VCSRO51_0987	COG0840	transmembrane signaling receptor activity
VCSRO51_0993	COG3015	lipoprotein NlpE involved in copper resistance
VCSRO51_0994	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VCSRO51_0995	COG2894	cell division
VCSRO51_0996	COG0850	regulation of cytokinetic process
VCSRO51_0997	COG3100	YcgL domain-containing protein
VCSRO51_0998	COG2951	lytic endotransglycosylase activity
VCSRO51_1000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO51_1001	COG3325	Belongs to the glycosyl hydrolase 18 family
VCSRO51_1001	COG3469	chitinase activity
VCSRO51_1002	COG3005	denitrification pathway
VCSRO51_1003	COG0243	molybdopterin cofactor binding
VCSRO51_1006	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO51_1008	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VCSRO51_1015	COG4589	Belongs to the CDS family
VCSRO51_1017	COG3300	MHYT domain
VCSRO51_1017	COG5001	Diguanylate cyclase
VCSRO51_1020	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VCSRO51_1021	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCSRO51_1022	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCSRO51_1023	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCSRO51_1025	COG4191	Histidine kinase
VCSRO51_1026	COG0544	peptidyl-prolyl cis-trans isomerase activity
VCSRO51_1028	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VCSRO51_1029	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VCSRO51_1030	COG0776	regulation of translation
VCSRO51_1031	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO51_1032	COG1555	photosystem II stabilization
VCSRO51_1033	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VCSRO51_1034	COG0539	negative regulation of cytoplasmic translation
VCSRO51_1035	COG0776	regulation of translation
VCSRO51_1036	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VCSRO51_1037	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VCSRO51_1039	COG0601	transmembrane transport
VCSRO51_1040	COG4239	(ABC) transporter, permease
VCSRO51_1041	COG0747	negative chemotaxis
VCSRO51_1042	COG0444	Belongs to the ABC transporter superfamily
VCSRO51_1043	COG4608	Belongs to the ABC transporter superfamily
VCSRO51_1048	COG0583	DNA-binding transcription factor activity
VCSRO51_1050	COG0686	Belongs to the AlaDH PNT family
VCSRO51_1052	COG1674	ftsk spoiiie
VCSRO51_1053	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VCSRO51_1054	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCSRO51_1055	COG2186	Transcriptional regulator
VCSRO51_1059	COG0537	adenosine 5'-monophosphoramidase activity
VCSRO51_1064	COG3150	esterase
VCSRO51_1065	COG1252	NADH dehydrogenase
VCSRO51_1069	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VCSRO51_1071	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO51_1072	COG1136	(ABC) transporter
VCSRO51_1073	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO51_1075	COG0658	competence protein
VCSRO51_1075	COG2333	competence protein COMEC
VCSRO51_1076	COG1132	(ABC) transporter
VCSRO51_1077	COG1663	tetraacyldisaccharide 4'-kinase activity
VCSRO51_1078	COG2835	tetraacyldisaccharide 4'-kinase activity
VCSRO51_1079	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VCSRO51_1080	COG2719	SpoVR family
VCSRO51_1081	COG2718	Belongs to the UPF0229 family
VCSRO51_1082	COG2766	serine protein kinase
VCSRO51_1083	COG3013	Belongs to the UPF0304 family
VCSRO51_1085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VCSRO51_1086	COG0840	transmembrane signaling receptor activity
VCSRO51_1088	COG1882	Formate acetyltransferase
VCSRO51_1094	COG4160	amino acid transport
VCSRO51_1095	COG0708	Exodeoxyribonuclease III
VCSRO51_1096	COG0840	transmembrane signaling receptor activity
VCSRO51_1098	COG3923	Primosomal replication protein n
VCSRO51_1099	COG0730	response to heat
VCSRO51_1100	COG1199	ATP-dependent helicase activity
VCSRO51_1102	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCSRO51_1103	COG3012	SEC-C Motif Domain Protein
VCSRO51_1104	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCSRO51_1105	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO51_1106	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCSRO51_1107	COG0215	cysteine-tRNA ligase activity
VCSRO51_1108	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VCSRO51_1109	COG0632	four-way junction helicase activity
VCSRO51_1112	COG1271	oxidase subunit
VCSRO51_1113	COG1294	oxidase, subunit
VCSRO51_1114	COG4890	Cyd operon protein YbgT
VCSRO51_1115	COG0824	Thioesterase
VCSRO51_1116	COG0811	peptide transport
VCSRO51_1119	COG0823	Involved in the tonB-independent uptake of proteins
VCSRO51_1120	COG2885	chlorophyll binding
VCSRO51_1122	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VCSRO51_1124	COG0784	Response regulator, receiver
VCSRO51_1124	COG5002	protein histidine kinase activity
VCSRO51_1126	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO51_1128	COG3284	Transcriptional regulator
VCSRO51_1129	COG4628	conserved protein (DUF2132)
VCSRO51_1131	COG0415	Belongs to the DNA photolyase family
VCSRO51_1144	COG2003	Belongs to the UPF0758 family
VCSRO51_1146	COG4409	exo-alpha-(2->6)-sialidase activity
VCSRO51_1147	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VCSRO51_1148	COG1940	carbohydrate kinase activity
VCSRO51_1150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCSRO51_1151	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCSRO51_1152	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCSRO51_1153	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VCSRO51_1154	COG1737	Transcriptional regulator
VCSRO51_1155	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VCSRO51_1156	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VCSRO51_1159	COG2801	Transposase and inactivated derivatives
VCSRO51_1167	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VCSRO51_1175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VCSRO51_1176	COG0582	viral genome integration into host DNA
VCSRO51_1177	COG0582	viral genome integration into host DNA
VCSRO51_1180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO51_1182	COG3008	intermembrane lipid transfer
VCSRO51_1182	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCSRO51_1183	COG2995	paraquat-inducible protein a
VCSRO51_1184	COG1309	transcriptional regulator
VCSRO51_1185	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO51_1189	COG1960	acyl-CoA dehydrogenase activity
VCSRO51_1190	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCSRO51_1191	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VCSRO51_1193	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VCSRO51_1196	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCSRO51_1197	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCSRO51_1198	COG0297	glycogen (starch) synthase activity
VCSRO51_1202	COG3070	regulator of competence-specific genes
VCSRO51_1203	COG1609	Transcriptional regulator
VCSRO51_1205	COG0745	RESPONSE REGULATOR receiver
VCSRO51_1206	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCSRO51_1207	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCSRO51_1208	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VCSRO51_1209	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VCSRO51_1213	COG1032	radical SAM domain protein
VCSRO51_1214	COG5001	Diguanylate cyclase
VCSRO51_1215	COG0612	Peptidase, M16
VCSRO51_1218	COG0583	DNA-binding transcription factor activity
VCSRO51_1219	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VCSRO51_1221	COG2350	Protein conserved in bacteria
VCSRO51_1222	COG1607	acyl-coa hydrolase
VCSRO51_1225	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCSRO51_1226	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCSRO51_1228	COG2116	formate transmembrane transporter activity
VCSRO51_1229	COG4459	periplasmic nitrate reductase
VCSRO51_1230	COG3005	denitrification pathway
VCSRO51_1231	COG0243	molybdopterin cofactor binding
VCSRO51_1234	COG1227	inorganic diphosphatase activity
VCSRO51_1237	COG4172	Belongs to the ABC transporter superfamily
VCSRO51_1240	COG4168	peptide transport system, permease
VCSRO51_1242	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VCSRO51_1243	COG1842	Phage shock protein A
VCSRO51_1246	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO51_1249	COG2818	Glycosylase
VCSRO51_1250	COG0589	response to stress
VCSRO51_1252	COG0626	cystathionine gamma-synthase activity
VCSRO51_1254	COG0733	neurotransmitter:sodium symporter activity
VCSRO51_1255	COG0564	pseudouridine synthase activity
VCSRO51_1256	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VCSRO51_1257	COG4136	ATPase activity
VCSRO51_1258	COG4135	transport system, permease component
VCSRO51_1259	COG4134	Bacterial extracellular solute-binding protein
VCSRO51_1261	COG3313	Fe-S protein
VCSRO51_1263	COG0842	Transport permease protein
VCSRO51_1264	COG1131	(ABC) transporter
VCSRO51_1265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO51_1266	COG0814	amino acid
VCSRO51_1268	COG2239	Acts as a magnesium transporter
VCSRO51_1271	COG4934	collagen metabolic process
VCSRO51_1277	COG0840	transmembrane signaling receptor activity
VCSRO51_1279	COG2203	Gaf domain
VCSRO51_1279	COG3706	GGDEF domain
VCSRO51_1279	COG4251	negative regulation of phosphorylation
VCSRO51_1279	COG5001	Diguanylate cyclase
VCSRO51_1280	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VCSRO51_1284	COG1061	Type III restriction enzyme res subunit
VCSRO51_1285	COG1187	pseudouridine synthase activity
VCSRO51_1286	COG2814	Major facilitator Superfamily
VCSRO51_1288	COG0702	epimerase
VCSRO51_1289	COG0534	Mate efflux family protein
VCSRO51_1290	COG4181	ATPase activity
VCSRO51_1291	COG0577	efflux transmembrane transporter activity
VCSRO51_1293	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCSRO51_1295	COG1748	Saccharopine dehydrogenase
VCSRO51_1298	COG1538	Outer membrane efflux protein
VCSRO51_1300	COG3385	transposase activity
VCSRO51_1303	COG0583	DNA-binding transcription factor activity
VCSRO51_1305	COG1451	nucleotide metabolic process
VCSRO51_1308	COG3063	Type IV pilus biogenesis stability protein PilW
VCSRO51_1309	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VCSRO51_1313	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO51_1316	COG3290	protein histidine kinase activity
VCSRO51_1317	COG4565	transcriptional regulatory protein
VCSRO51_1319	COG0784	Response regulator, receiver
VCSRO51_1319	COG0835	chemotaxis
VCSRO51_1327	COG1085	galactose-1-phosphate uridylyltransferase
VCSRO51_1328	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VCSRO51_1329	COG2017	converts alpha-aldose to the beta-anomer
VCSRO51_1331	COG2200	EAL domain
VCSRO51_1331	COG2199	diguanylate cyclase activity
VCSRO51_1334	COG3527	Alpha-acetolactate decarboxylase
VCSRO51_1337	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCSRO51_1342	COG3097	Belongs to the UPF0267 family
VCSRO51_1347	COG1271	oxidase subunit
VCSRO51_1348	COG1294	oxidase, subunit
VCSRO51_1349	COG1136	(ABC) transporter
VCSRO51_1349	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO51_1350	COG0577	efflux transmembrane transporter activity
VCSRO51_1350	COG1136	(ABC) transporter
VCSRO51_1351	COG0577	efflux transmembrane transporter activity
VCSRO51_1356	COG2723	6-phospho-beta-galactosidase activity
VCSRO51_1357	COG1609	Transcriptional regulator
VCSRO51_1358	COG0251	oxidation-reduction process
VCSRO51_1359	COG2731	YhcH YjgK YiaL family protein
VCSRO51_1360	COG0584	glycerophosphoryl diester phosphodiesterase
VCSRO51_1361	COG1349	DNA-binding transcription factor activity
VCSRO51_1362	COG3842	ATPase activity
VCSRO51_1363	COG0395	ABC-type sugar transport system, permease component
VCSRO51_1364	COG1175	transmembrane transport
VCSRO51_1367	COG0811	peptide transport
VCSRO51_1368	COG0811	peptide transport
VCSRO51_1369	COG0848	biopolymer transport protein
VCSRO51_1370	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCSRO51_1372	COG1793	dna ligase
VCSRO51_1374	COG0534	Mate efflux family protein
VCSRO51_1376	COG3001	Fructosamine kinase
VCSRO51_1378	COG0791	NLP P60 protein
VCSRO51_1379	COG0840	transmembrane signaling receptor activity
VCSRO51_1379	COG3290	protein histidine kinase activity
VCSRO51_1381	COG3148	PFAM DTW domain containing protein
VCSRO51_1382	COG1940	carbohydrate kinase activity
VCSRO51_1384	COG0303	'Molybdopterin
VCSRO51_1385	COG0746	molybdenum cofactor guanylyltransferase activity
VCSRO51_1386	COG3842	ATPase activity
VCSRO51_1387	COG4662	Binding-protein-dependent transport system inner membrane component
VCSRO51_1389	COG2204	response regulator
VCSRO51_1390	COG3852	Histidine kinase
VCSRO51_1391	COG0488	(ABC) transporter
VCSRO51_1392	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VCSRO51_1398	COG3383	formate dehydrogenase (NAD+) activity
VCSRO51_1398	COG3383	formate dehydrogenase (NAD+) activity
VCSRO51_1399	COG0437	4 iron, 4 sulfur cluster binding
VCSRO51_1402	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VCSRO51_1403	COG1666	GTP binding
VCSRO51_1404	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO51_1407	COG2996	Protein conserved in bacteria
VCSRO51_1409	COG3008	intermembrane lipid transfer
VCSRO51_1410	COG2995	paraquat-inducible protein a
VCSRO51_1411	COG1132	(ABC) transporter
VCSRO51_1412	COG1956	GAF domain-containing protein
VCSRO51_1413	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VCSRO51_1416	COG0308	aminopeptidase N
VCSRO51_1419	COG0167	dihydroorotate dehydrogenase activity
VCSRO51_1422	COG0116	Belongs to the methyltransferase superfamily
VCSRO51_1422	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCSRO51_1424	COG0488	(ABC) transporter
VCSRO51_1427	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCSRO51_1428	COG1067	ATP-dependent peptidase activity
VCSRO51_1429	COG3120	sequence-specific DNA binding
VCSRO51_1432	COG1073	alpha beta
VCSRO51_1432	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VCSRO51_1432	COG3064	Membrane
VCSRO51_1433	COG1073	alpha beta
VCSRO51_1433	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VCSRO51_1433	COG3064	Membrane
VCSRO51_1434	COG1073	alpha beta
VCSRO51_1434	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VCSRO51_1434	COG3064	Membrane
VCSRO51_1435	COG2994	toxin metabolic process
VCSRO51_1440	COG2205	protein histidine kinase activity
VCSRO51_1440	COG0784	Response regulator, receiver
VCSRO51_1443	COG3278	Belongs to the heme-copper respiratory oxidase family
VCSRO51_1446	COG2010	Cytochrome c
VCSRO51_1448	COG2217	Heavy metal translocating P-type atpase
VCSRO51_1451	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VCSRO51_1452	COG0589	response to stress
VCSRO51_1453	COG0037	tRNA processing
VCSRO51_1457	COG3842	ATPase activity
VCSRO51_1459	COG1177	transmembrane transport
VCSRO51_1461	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCSRO51_1464	COG1115	amino acid carrier protein
VCSRO51_1465	COG1280	lysine exporter protein (LysE YggA)
VCSRO51_1469	COG3501	Rhs element vgr protein
VCSRO51_1471	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VCSRO51_1473	COG2814	Major facilitator Superfamily
VCSRO51_1474	COG1566	PFAM secretion protein HlyD family protein
VCSRO51_1475	COG1538	Outer membrane efflux protein
VCSRO51_1477	COG0513	Belongs to the DEAD box helicase family
VCSRO51_1481	COG0415	Belongs to the DNA photolyase family
VCSRO51_1482	COG0477	Major facilitator Superfamily
VCSRO51_1483	COG0583	DNA-binding transcription factor activity
VCSRO51_1484	COG0402	S-adenosylhomocysteine deaminase activity
VCSRO51_1485	COG0095	Lipoate-protein ligase
VCSRO51_1486	COG0443	Heat shock 70 kDa protein
VCSRO51_1488	COG1643	Atp-dependent helicase
VCSRO51_1495	COG0443	Heat shock 70 kDa protein
VCSRO51_1496	COG0443	Heat shock 70 kDa protein
VCSRO51_1497	COG3706	GGDEF domain
VCSRO51_1503	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VCSRO51_1504	COG0602	queuosine metabolic process
VCSRO51_1506	COG0561	phosphatase activity
VCSRO51_1508	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO51_1509	COG4597	amino acid ABC transporter
VCSRO51_1510	COG0765	amino acid transport
VCSRO51_1511	COG1126	abc transporter atp-binding protein
VCSRO51_1512	COG0670	Belongs to the BI1 family
VCSRO51_1513	COG2920	part of a sulfur-relay system
VCSRO51_1514	COG1254	Belongs to the acylphosphatase family
VCSRO51_1515	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCSRO51_1516	COG3706	GGDEF domain
VCSRO51_1518	COG3850	Histidine kinase
VCSRO51_1518	COG4999	Histidine kinase
VCSRO51_1518	COG3437	response regulator, receiver
VCSRO51_1518	COG2205	protein histidine kinase activity
VCSRO51_1521	COG3437	response regulator, receiver
VCSRO51_1522	COG0625	glutathione transferase activity
VCSRO51_1524	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VCSRO51_1526	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO51_1532	COG0372	Belongs to the citrate synthase family
VCSRO51_1533	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VCSRO51_1541	COG1129	ABC transporter
VCSRO51_1546	COG0745	RESPONSE REGULATOR receiver
VCSRO51_1547	COG2205	protein histidine kinase activity
VCSRO51_1548	COG3713	MltA-interacting MipA family protein
VCSRO51_1549	COG2990	Protein conserved in bacteria
VCSRO51_1551	COG2205	protein histidine kinase activity
VCSRO51_1552	COG0471	metal ion transport
VCSRO51_1554	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCSRO51_1557	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO51_1559	COG3768	UPF0283 membrane protein
VCSRO51_1560	COG3106	COG3106 Predicted ATPase
VCSRO51_1563	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCSRO51_1564	COG0494	nUDIX hydrolase
VCSRO51_1565	COG0814	amino acid
VCSRO51_1566	COG1760	l-serine dehydratase
VCSRO51_1567	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO51_1568	COG1136	(ABC) transporter
VCSRO51_1568	COG0577	efflux transmembrane transporter activity
VCSRO51_1570	COG0720	synthase
VCSRO51_1572	COG0017	Asparaginyl-tRNA synthetase
VCSRO51_1573	COG0351	phosphomethylpyrimidine kinase
VCSRO51_1574	COG1448	Aminotransferase
VCSRO51_1577	COG0840	transmembrane signaling receptor activity
VCSRO51_1578	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
VCSRO51_1579	COG2943	transferase activity, transferring hexosyl groups
VCSRO51_1580	COG1609	Transcriptional regulator
VCSRO51_1581	COG3394	polysaccharide catabolic process
VCSRO51_1582	COG1486	melibiose metabolic process
VCSRO51_1583	COG1447	Phosphotransferase system cellobiose-specific component IIA
VCSRO51_1585	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VCSRO51_1586	COG0726	polysaccharide deacetylase
VCSRO51_1587	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VCSRO51_1588	COG1846	Transcriptional regulator
VCSRO51_1593	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCSRO51_1596	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCSRO51_1597	COG3108	Peptidase M15
VCSRO51_1603	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VCSRO51_1605	COG2814	Major facilitator Superfamily
VCSRO51_1607	COG1054	Belongs to the UPF0176 family
VCSRO51_1609	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCSRO51_1610	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCSRO51_1611	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCSRO51_1620	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
VCSRO51_1621	COG4139	cobalamin transport
VCSRO51_1622	COG2988	succinylglutamate desuccinylase activity
VCSRO51_1625	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VCSRO51_1626	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VCSRO51_1627	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO51_1628	COG1823	symporter activity
VCSRO51_1629	COG2925	Exonuclease
VCSRO51_1630	COG1380	Effector of murein hydrolase LrgA
VCSRO51_1631	COG1346	cytolysis
VCSRO51_1638	COG0776	regulation of translation
VCSRO51_1639	COG0072	phenylalanine-tRNA ligase activity
VCSRO51_1639	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO51_1640	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VCSRO51_1648	COG0322	excinuclease ABC activity
VCSRO51_1649	COG2197	response regulator
VCSRO51_1650	COG0417	DNA replication proofreading
VCSRO51_1651	COG5001	Diguanylate cyclase
VCSRO51_1653	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCSRO51_1654	COG3099	Belongs to the UPF0263 family
VCSRO51_1657	COG1228	amidohydrolase
VCSRO51_1658	COG0010	Belongs to the arginase family
VCSRO51_1659	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VCSRO51_1660	COG2986	histidine ammonia-lyase
VCSRO51_1664	COG0247	lactate metabolic process
VCSRO51_1664	COG0277	FAD linked oxidase domain protein
VCSRO51_1667	COG2885	chlorophyll binding
VCSRO51_1671	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VCSRO51_1673	COG0281	malic enzyme
VCSRO51_1675	COG2949	membrane
VCSRO51_1676	COG3706	GGDEF domain
VCSRO51_1677	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCSRO51_1679	COG0492	ferredoxin-NADP+ reductase activity
VCSRO51_1680	COG4988	ABC transporter
VCSRO51_1681	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VCSRO51_1682	COG1187	pseudouridine synthase activity
VCSRO51_1683	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO51_1684	COG0613	PHP domain protein
VCSRO51_1685	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCSRO51_1686	COG0512	Glutamine amidotransferase of anthranilate synthase
VCSRO51_1687	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VCSRO51_1688	COG0134	indole-3-glycerol-phosphate synthase activity
VCSRO51_1688	COG0135	phosphoribosylanthranilate isomerase activity
VCSRO51_1689	COG0133	tryptophan synthase activity
VCSRO51_1690	COG0159	tryptophan synthase activity
VCSRO51_1692	COG1435	thymidine kinase activity
VCSRO51_1693	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VCSRO51_1694	COG1801	Protein of unknown function DUF72
VCSRO51_1695	COG4106	trans-aconitate 2-methyltransferase activity
VCSRO51_1696	COG0500	methyltransferase
VCSRO51_1697	COG0189	ligase activity
VCSRO51_1697	COG4067	protein conserved in archaea
VCSRO51_1700	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VCSRO51_1702	COG3852	Histidine kinase
VCSRO51_1705	COG3070	regulator of competence-specific genes
VCSRO51_1707	COG2431	L-lysine efflux transmembrane transporter activity
VCSRO51_1709	COG0076	glutamate decarboxylase activity
VCSRO51_1710	COG1737	Transcriptional regulator
VCSRO51_1711	COG1454	alcohol dehydrogenase
VCSRO51_1711	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO51_1712	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCSRO51_1713	COG3273	potassium ion transport
VCSRO51_1713	COG2985	domain, Protein
VCSRO51_1714	COG0542	response to heat
VCSRO51_1715	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VCSRO51_1716	COG1278	Cold shock
VCSRO51_1718	COG1187	pseudouridine synthase activity
VCSRO51_1719	COG0140	phosphoribosyl-ATP diphosphatase activity
VCSRO51_1719	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VCSRO51_1720	COG0107	imidazoleglycerol-phosphate synthase activity
VCSRO51_1721	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VCSRO51_1722	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VCSRO51_1723	COG0131	Imidazoleglycerol-phosphate dehydratase
VCSRO51_1723	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCSRO51_1724	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VCSRO51_1725	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VCSRO51_1726	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VCSRO51_1727	COG1757	Na H antiporter
VCSRO51_1728	COG2916	Histone family protein nucleoid-structuring protein H-NS
VCSRO51_1729	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO51_1730	COG0482	sulfurtransferase activity
VCSRO51_1731	COG2915	High frequency lysogenization protein hflD homolog
VCSRO51_1732	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VCSRO51_1734	COG2268	Band 7 protein
VCSRO51_1736	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VCSRO51_1739	COG0300	oxidoreductase activity
VCSRO51_1741	COG0501	Belongs to the peptidase M48B family
VCSRO51_1743	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VCSRO51_1744	COG2226	methyltransferase
VCSRO51_1745	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO51_1746	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCSRO51_1747	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VCSRO51_1748	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VCSRO51_1749	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VCSRO51_1750	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VCSRO51_1751	COG0653	protein targeting
VCSRO51_1752	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO51_1753	COG2199	diguanylate cyclase activity
VCSRO51_1753	COG2203	Gaf domain
VCSRO51_1755	COG4120	Belongs to the binding-protein-dependent transport system permease family
VCSRO51_1757	COG4628	conserved protein (DUF2132)
VCSRO51_1758	COG3092	negative regulation of chromosome organization
VCSRO51_1759	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCSRO51_1760	COG0280	phosphate acetyltransferase
VCSRO51_1760	COG0857	belongs to the CobB CobQ family
VCSRO51_1761	COG0435	Glutathione S-transferase
VCSRO51_1762	COG4608	Belongs to the ABC transporter superfamily
VCSRO51_1763	COG0444	Belongs to the ABC transporter superfamily
VCSRO51_1764	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO51_1765	COG0601	transmembrane transport
VCSRO51_1769	COG2204	response regulator
VCSRO51_1770	COG5001	Diguanylate cyclase
VCSRO51_1770	COG3300	MHYT domain
VCSRO51_1771	COG4191	Histidine kinase
VCSRO51_1772	COG5002	protein histidine kinase activity
VCSRO51_1774	COG2201	protein-glutamate methylesterase activity
VCSRO51_1777	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO51_1780	COG1881	PFAM PEBP family protein
VCSRO51_1785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO51_1786	COG0640	Transcriptional regulator
VCSRO51_1787	COG3706	GGDEF domain
VCSRO51_1791	COG1946	Acyl-CoA thioesterase
VCSRO51_1792	COG1522	sequence-specific DNA binding
VCSRO51_1794	COG0616	signal peptide processing
VCSRO51_1795	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO51_1800	COG2983	Belongs to the UPF0260 family
VCSRO51_1802	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VCSRO51_1803	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VCSRO51_1804	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
VCSRO51_1805	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VCSRO51_1806	COG2832	Protein of unknown function (DUF454)
VCSRO51_1808	COG0745	RESPONSE REGULATOR receiver
VCSRO51_1809	COG0583	DNA-binding transcription factor activity
VCSRO51_1810	COG0778	Nitroreductase
VCSRO51_1811	COG1024	Enoyl-CoA hydratase
VCSRO51_1811	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCSRO51_1812	COG0183	Belongs to the thiolase family
VCSRO51_1815	COG2067	long-chain fatty acid transport protein
VCSRO51_1817	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VCSRO51_1818	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VCSRO51_1819	COG2982	Protein involved in outer membrane biogenesis
VCSRO51_1820	COG0572	uridine kinase
VCSRO51_1821	COG0489	protein tyrosine kinase activity
VCSRO51_1822	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO51_1822	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO51_1824	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO51_1826	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
VCSRO51_1826	COG0517	IMP dehydrogenase activity
VCSRO51_1826	COG0617	tRNA 3'-terminal CCA addition
VCSRO51_1827	COG2199	diguanylate cyclase activity
VCSRO51_1828	COG0314	molybdopterin synthase activity
VCSRO51_1829	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VCSRO51_1830	COG0315	cyclic pyranopterin monophosphate synthase activity
VCSRO51_1831	COG0521	Mo-molybdopterin cofactor biosynthetic process
VCSRO51_1832	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VCSRO51_1833	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VCSRO51_1834	COG2198	Histidine kinase
VCSRO51_1835	COG2204	response regulator
VCSRO51_1836	COG0556	nucleotide-excision repair
VCSRO51_1838	COG4657	Part of a membrane complex involved in electron transport
VCSRO51_1839	COG2878	Part of a membrane complex involved in electron transport
VCSRO51_1840	COG4656	Part of a membrane complex involved in electron transport
VCSRO51_1843	COG4660	Part of a membrane complex involved in electron transport
VCSRO51_1844	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VCSRO51_1845	COG0346	lactoylglutathione lyase activity
VCSRO51_1848	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VCSRO51_1849	COG2056	Na+-H+ antiporter family
VCSRO51_1850	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VCSRO51_1851	COG1286	toxin biosynthetic process
VCSRO51_1852	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VCSRO51_1853	COG0285	dihydrofolate synthase activity
VCSRO51_1854	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VCSRO51_1855	COG0101	tRNA pseudouridine synthase activity
VCSRO51_1858	COG2190	(PTS) system
VCSRO51_1858	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO51_1858	COG1263	PTS System
VCSRO51_1859	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VCSRO51_1860	COG1940	carbohydrate kinase activity
VCSRO51_1860	COG1846	Transcriptional regulator
VCSRO51_1861	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCSRO51_1861	COG4651	solute:proton antiporter activity
VCSRO51_1862	COG0367	asparagine synthase
VCSRO51_1865	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VCSRO51_1866	COG0563	adenylate kinase activity
VCSRO51_1867	COG0326	Molecular chaperone. Has ATPase activity
VCSRO51_1868	COG3710	Transcriptional regulator
VCSRO51_1871	COG0622	Phosphoesterase
VCSRO51_1872	COG1090	epimerase
VCSRO51_1873	COG0300	oxidoreductase activity
VCSRO51_1874	COG3118	belongs to the thioredoxin family
VCSRO51_1875	COG0330	HflC and HflK could
VCSRO51_1876	COG1585	Membrane protein implicated in regulation of membrane protease activity
VCSRO51_1877	COG0789	Transcriptional regulator
VCSRO51_1880	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VCSRO51_1881	COG3115	cell septum assembly
VCSRO51_1882	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VCSRO51_1883	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VCSRO51_1884	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO51_1886	COG2190	(PTS) system
VCSRO51_1887	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO51_1888	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCSRO51_1889	COG1702	phosphate starvation-inducible protein PhoH
VCSRO51_1890	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VCSRO51_1891	COG4535	Mg2 and Co2 transporter CorC
VCSRO51_1892	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VCSRO51_1893	COG2888	peptidyl-tyrosine sulfation
VCSRO51_1894	COG0495	leucyl-tRNA aminoacylation
VCSRO51_1895	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VCSRO51_1896	COG1466	dna polymerase III delta subunit
VCSRO51_1897	COG0799	negative regulation of ribosome biogenesis
VCSRO51_1898	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VCSRO51_1899	COG0768	penicillin binding
VCSRO51_1900	COG0772	Belongs to the SEDS family
VCSRO51_1901	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCSRO51_1902	COG1686	Belongs to the peptidase S11 family
VCSRO51_1903	COG2921	Belongs to the UPF0250 family
VCSRO51_1904	COG0321	lipoyl(octanoyl) transferase activity
VCSRO51_1905	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VCSRO51_1907	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCSRO51_1912	COG1596	polysaccharide export
VCSRO51_1914	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCSRO51_1920	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
VCSRO51_1922	COG0438	transferase activity, transferring glycosyl groups
VCSRO51_1924	COG1045	serine acetyltransferase
VCSRO51_1928	COG1045	serine acetyltransferase
VCSRO51_1929	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VCSRO51_1930	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VCSRO51_1933	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO51_1939	COG0366	Alpha amylase catalytic
VCSRO51_1941	COG1263	PTS System
VCSRO51_1941	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO51_1942	COG1609	Transcriptional regulator
VCSRO51_1943	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCSRO51_1944	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VCSRO51_1945	COG2011	ABC-type metal ion transport system permease component
VCSRO51_1946	COG1464	Belongs to the NlpA lipoprotein family
VCSRO51_1947	COG3385	transposase activity
VCSRO51_1948	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VCSRO51_1950	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCSRO51_1950	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCSRO51_1953	COG1611	Belongs to the LOG family
VCSRO51_1954	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO51_1955	COG2363	Small membrane protein
VCSRO51_1956	COG0583	DNA-binding transcription factor activity
VCSRO51_1957	COG0301	tRNA thio-modification
VCSRO51_1957	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO51_1959	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VCSRO51_1960	COG1722	exodeoxyribonuclease VII activity
VCSRO51_1961	COG0142	geranyltranstransferase activity
VCSRO51_1962	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VCSRO51_1963	COG0564	pseudouridine synthase activity
VCSRO51_1964	COG3098	single-species biofilm formation
VCSRO51_1967	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO51_1969	COG1671	Belongs to the UPF0178 family
VCSRO51_1970	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCSRO51_1971	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCSRO51_1972	COG0254	rRNA binding
VCSRO51_1973	COG1720	tRNA m6t6A37 methyltransferase activity
VCSRO51_1974	COG0442	prolyl-tRNA aminoacylation
VCSRO51_1978	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VCSRO51_1978	COG0047	phosphoribosylformylglycinamidine synthase activity
VCSRO51_1979	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VCSRO51_1982	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCSRO51_1988	COG0484	heat shock protein binding
VCSRO51_1989	COG0443	Heat shock 70 kDa protein
VCSRO51_1990	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VCSRO51_1991	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VCSRO51_1992	COG0497	DNA recombination
VCSRO51_1993	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO51_1994	COG2914	Belongs to the UPF0125 (RnfH) family
VCSRO51_1995	COG2867	negative regulation of translational initiation
VCSRO51_1996	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VCSRO51_1998	COG0582	viral genome integration into host DNA
VCSRO51_2003	COG1203	CRISPR-associated helicase, Cas3
VCSRO51_2004	COG1518	maintenance of DNA repeat elements
VCSRO51_2007	COG3501	Rhs element vgr protein
VCSRO51_2018	COG1061	Type III restriction enzyme res subunit
VCSRO51_2022	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VCSRO51_2023	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VCSRO51_2024	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCSRO51_2028	COG3051	citrate lyase alpha subunit
VCSRO51_2029	COG2301	Belongs to the HpcH HpaI aldolase family
VCSRO51_2030	COG3052	prosthetic group binding
VCSRO51_2031	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
VCSRO51_2033	COG3630	sodium ion export across plasma membrane
VCSRO51_2034	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO51_2034	COG5016	pyruvate
VCSRO51_2035	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCSRO51_2037	COG4565	transcriptional regulatory protein
VCSRO51_2040	COG0583	DNA-binding transcription factor activity
VCSRO51_2042	COG1115	amino acid carrier protein
VCSRO51_2043	COG2977	Belongs to the P-Pant transferase superfamily
VCSRO51_2044	COG1120	ATPase activity
VCSRO51_2045	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO51_2046	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO51_2047	COG4592	Periplasmic binding protein
VCSRO51_2049	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO51_2050	COG1169	isochorismate synthase
VCSRO51_2051	COG1021	2,3-dihydroxybenzoate-AMP ligase
VCSRO51_2052	COG1535	isochorismatase
VCSRO51_2052	COG3433	isochorismatase activity
VCSRO51_2053	COG1584	GPR1 FUN34 yaaH family protein
VCSRO51_2055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VCSRO51_2055	COG0519	Catalyzes the synthesis of GMP from XMP
VCSRO51_2056	COG0516	GMP reductase activity
VCSRO51_2056	COG0517	IMP dehydrogenase activity
VCSRO51_2057	COG1570	exodeoxyribonuclease VII activity
VCSRO51_2060	COG1160	GTP binding
VCSRO51_2061	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO51_2062	COG2976	Protein conserved in bacteria
VCSRO51_2063	COG0124	histidyl-tRNA synthetase
VCSRO51_2064	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VCSRO51_2067	COG0105	UTP biosynthetic process
VCSRO51_2068	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCSRO51_2069	COG2975	iron-sulfur cluster assembly
VCSRO51_2070	COG0633	Ferredoxin
VCSRO51_2074	COG0822	iron-sulfur transferase activity
VCSRO51_2076	COG1959	2 iron, 2 sulfur cluster binding
VCSRO51_2078	COG0483	inositol monophosphate 1-phosphatase activity
VCSRO51_2079	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO51_2080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO51_2081	COG1862	Preprotein translocase
VCSRO51_2083	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
VCSRO51_2084	COG0517	IMP dehydrogenase activity
VCSRO51_2086	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VCSRO51_2087	COG0583	DNA-binding transcription factor activity
VCSRO51_2088	COG0450	alkyl hydroperoxide reductase
VCSRO51_2089	COG3142	Participates in the control of copper homeostasis
VCSRO51_2092	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCSRO51_2093	COG0581	inorganic phosphate transmembrane transporter activity
VCSRO51_2095	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VCSRO51_2096	COG0248	Ppx GppA phosphatase
VCSRO51_2098	COG5002	protein histidine kinase activity
VCSRO51_2099	COG0745	RESPONSE REGULATOR receiver
VCSRO51_2101	COG0826	peptidase U32
VCSRO51_2102	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCSRO51_2110	COG0542	response to heat
VCSRO51_2111	COG1496	oxidoreductase activity
VCSRO51_2112	COG0564	pseudouridine synthase activity
VCSRO51_2113	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO51_2114	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCSRO51_2115	COG0077	Prephenate dehydratase
VCSRO51_2115	COG1605	Chorismate mutase
VCSRO51_2116	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCSRO51_2117	COG5001	Diguanylate cyclase
VCSRO51_2119	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VCSRO51_2121	COG0488	(ABC) transporter
VCSRO51_2123	COG0287	Prephenate dehydrogenase
VCSRO51_2123	COG1605	Chorismate mutase
VCSRO51_2124	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO51_2125	COG3275	phosphorelay sensor kinase activity
VCSRO51_2126	COG3279	Response regulator of the LytR AlgR family
VCSRO51_2127	COG1472	Belongs to the glycosyl hydrolase 3 family
VCSRO51_2128	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VCSRO51_2129	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCSRO51_2131	COG1966	Carbon starvation protein
VCSRO51_2132	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VCSRO51_2133	COG1047	Peptidyl-prolyl cis-trans
VCSRO51_2134	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VCSRO51_2136	COG0196	riboflavin kinase activity
VCSRO51_2137	COG0728	peptidoglycan biosynthetic process
VCSRO51_2138	COG0268	Binds directly to 16S ribosomal RNA
VCSRO51_2139	COG0640	Transcriptional regulator
VCSRO51_2140	COG0583	DNA-binding transcription factor activity
VCSRO51_2141	COG1283	sodium-dependent phosphate transmembrane transporter activity
VCSRO51_2142	COG3385	transposase activity
VCSRO51_2144	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VCSRO51_2145	COG0730	response to heat
VCSRO51_2146	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
VCSRO51_2147	COG0494	nUDIX hydrolase
VCSRO51_2148	COG3066	DNA modification
VCSRO51_2149	COG0667	Aldo Keto reductase
VCSRO51_2151	COG2204	response regulator
VCSRO51_2153	COG2801	Transposase and inactivated derivatives
VCSRO51_2154	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VCSRO51_2155	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VCSRO51_2158	COG0513	Belongs to the DEAD box helicase family
VCSRO51_2163	COG3153	acetyltransferase
VCSRO51_2164	COG3154	lipid carrier protein
VCSRO51_2166	COG0826	peptidase U32
VCSRO51_2167	COG0826	peptidase U32
VCSRO51_2172	COG1185	polyribonucleotide nucleotidyltransferase activity
VCSRO51_2173	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VCSRO51_2175	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VCSRO51_2176	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VCSRO51_2177	COG0195	Participates in both transcription termination and antitermination
VCSRO51_2178	COG0779	Required for maturation of 30S ribosomal subunits
VCSRO51_2181	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCSRO51_2184	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VCSRO51_2185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VCSRO51_2186	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VCSRO51_2187	COG1534	Rna-binding protein
VCSRO51_2188	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO51_2189	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCSRO51_2190	COG2027	D-alanyl-D-alanine carboxypeptidase
VCSRO51_2191	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCSRO51_2192	COG0739	heme binding
VCSRO51_2195	COG0316	Belongs to the HesB IscA family
VCSRO51_2196	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VCSRO51_2198	COG0628	permease
VCSRO51_2199	COG2813	Specifically methylates the guanine in position
VCSRO51_2200	COG2205	protein histidine kinase activity
VCSRO51_2200	COG0784	Response regulator, receiver
VCSRO51_2201	COG0747	negative chemotaxis
VCSRO51_2202	COG0601	transmembrane transport
VCSRO51_2203	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO51_2204	COG0444	Belongs to the ABC transporter superfamily
VCSRO51_2205	COG4608	Belongs to the ABC transporter superfamily
VCSRO51_2207	COG2971	BadF BadG BcrA BcrD
VCSRO51_2211	COG3842	ATPase activity
VCSRO51_2213	COG1840	ABC-type Fe3 transport system, periplasmic component
VCSRO51_2214	COG0004	ammonium transporteR
VCSRO51_2215	COG0347	Belongs to the P(II) protein family
VCSRO51_2216	COG3112	Uncharacterised protein family (UPF0231)
VCSRO51_2217	COG1049	propionate catabolic process, 2-methylcitrate cycle
VCSRO51_2218	COG1752	Esterase of the alpha-beta hydrolase superfamily
VCSRO51_2219	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VCSRO51_2220	COG1643	Atp-dependent helicase
VCSRO51_2222	COG1489	DNA binding
VCSRO51_2224	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCSRO51_2226	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCSRO51_2227	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VCSRO51_2228	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VCSRO51_2229	COG0842	Transport permease protein
VCSRO51_2230	COG1131	(ABC) transporter
VCSRO51_2231	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO51_2232	COG0288	reversible hydration of carbon dioxide
VCSRO51_2235	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VCSRO51_2236	COG3107	peptidoglycan biosynthetic process
VCSRO51_2237	COG0792	nuclease activity
VCSRO51_2238	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCSRO51_2239	COG2823	Periplasmic or secreted lipoprotein
VCSRO51_2240	COG2969	positive regulation of protein catabolic process
VCSRO51_2241	COG0625	glutathione transferase activity
VCSRO51_2242	COG2857	Cytochrome c1
VCSRO51_2243	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VCSRO51_2244	COG0723	plastoquinol--plastocyanin reductase activity
VCSRO51_2245	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VCSRO51_2246	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VCSRO51_2247	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VCSRO51_2248	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VCSRO51_2250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCSRO51_2251	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCSRO51_2252	COG0335	large ribosomal subunit rRNA binding
VCSRO51_2253	COG0336	Belongs to the RNA methyltransferase TrmD family
VCSRO51_2254	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VCSRO51_2255	COG0228	four-way junction DNA binding
VCSRO51_2256	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VCSRO51_2258	COG4137	Cytochrome C assembly protein
VCSRO51_2259	COG4536	flavin adenine dinucleotide binding
VCSRO51_2260	COG1854	S-ribosylhomocysteine lyase activity
VCSRO51_2261	COG2918	glutathione biosynthetic process
VCSRO51_2262	COG0612	Peptidase, M16
VCSRO51_2263	COG1238	metal cluster binding
VCSRO51_2265	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCSRO51_2266	COG5016	pyruvate
VCSRO51_2266	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO51_2267	COG3630	sodium ion export across plasma membrane
VCSRO51_2276	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
VCSRO51_2277	COG0527	aspartate kinase activity
VCSRO51_2278	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VCSRO51_2279	COG2137	regulation of response to DNA damage stimulus
VCSRO51_2280	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VCSRO51_2282	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
VCSRO51_2283	COG4208	sulfate ABC transporter
VCSRO51_2287	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VCSRO51_2288	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCSRO51_2289	COG4942	peptidase
VCSRO51_2289	COG1388	LysM domain
VCSRO51_2290	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VCSRO51_2291	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VCSRO51_2292	COG0585	pseudouridine synthase activity
VCSRO51_2293	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VCSRO51_2294	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VCSRO51_2295	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VCSRO51_2296	COG1968	undecaprenyl-diphosphatase activity
VCSRO51_2297	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCSRO51_2298	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VCSRO51_2299	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VCSRO51_2301	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VCSRO51_2302	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VCSRO51_2303	COG1610	YqeY-like protein
VCSRO51_2308	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCSRO51_2309	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VCSRO51_2310	COG1349	DNA-binding transcription factor activity
VCSRO51_2315	COG1279	arginine transmembrane transporter activity
VCSRO51_2316	COG0668	transmembrane transport
VCSRO51_2317	COG0191	fructose-bisphosphate aldolase activity
VCSRO51_2318	COG0126	phosphoglycerate kinase activity
VCSRO51_2319	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO51_2320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO51_2321	COG4771	TonB-dependent receptor
VCSRO51_2322	COG0583	DNA-binding transcription factor activity
VCSRO51_2323	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCSRO51_2324	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VCSRO51_2325	COG3091	SprT-like family
VCSRO51_2326	COG2356	endonuclease I
VCSRO51_2327	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VCSRO51_2328	COG0189	ligase activity
VCSRO51_2329	COG1678	Uncharacterized ACR, COG1678
VCSRO51_2330	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VCSRO51_2331	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCSRO51_2335	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VCSRO51_2336	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VCSRO51_2337	COG0762	integral membrane protein
VCSRO51_2338	COG1872	DUF167
VCSRO51_2340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VCSRO51_2341	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VCSRO51_2342	COG2066	Belongs to the glutaminase family
VCSRO51_2343	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VCSRO51_2344	COG1194	a g-specific adenine glycosylase
VCSRO51_2345	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VCSRO51_2346	COG0741	lytic transglycosylase activity
VCSRO51_2357	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VCSRO51_2358	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VCSRO51_2359	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO51_2360	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VCSRO51_2361	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VCSRO51_2362	COG2967	ApaG domain
VCSRO51_2363	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VCSRO51_2365	COG3610	response to peptide
VCSRO51_2366	COG2966	Psort location CytoplasmicMembrane, score
VCSRO51_2367	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VCSRO51_2368	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VCSRO51_2369	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VCSRO51_2370	COG0142	geranyltranstransferase activity
VCSRO51_2371	COG0531	amino acid
VCSRO51_2372	COG0039	L-malate dehydrogenase activity
VCSRO51_2373	COG1438	arginine binding
VCSRO51_2374	COG2358	TRAP transporter, solute receptor (TAXI family
VCSRO51_2376	COG0589	response to stress
VCSRO51_2380	COG2235	arginine
VCSRO51_2381	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCSRO51_2382	COG1151	hydroxylamine reductase activity
VCSRO51_2383	COG0312	modulator of DNA gyrase
VCSRO51_2384	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VCSRO51_2385	COG3164	Protein of unknown function
VCSRO51_2387	COG1530	ribonuclease E activity
VCSRO51_2388	COG0424	maF-like protein
VCSRO51_2389	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VCSRO51_2390	COG1792	Involved in formation and maintenance of cell shape
VCSRO51_2391	COG1077	Cell shape determining protein MreB Mrl
VCSRO51_2397	COG2165	general secretion pathway protein
VCSRO51_2398	COG2165	general secretion pathway protein
VCSRO51_2400	COG1459	type II secretion system
VCSRO51_2401	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO51_2403	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO51_2403	COG3267	Type II secretory pathway component ExeA
VCSRO51_2408	COG2199	diguanylate cyclase activity
VCSRO51_2408	COG2200	EAL domain
VCSRO51_2410	COG2801	Transposase and inactivated derivatives
VCSRO51_2416	COG0629	single-stranded DNA binding
VCSRO51_2419	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VCSRO51_2422	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCSRO51_2423	COG0527	aspartate kinase activity
VCSRO51_2424	COG0646	methionine synthase
VCSRO51_2424	COG1410	methionine synthase
VCSRO51_2446	COG0175	sulfate reduction
VCSRO51_2447	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VCSRO51_2448	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCSRO51_2452	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO51_2453	COG0735	belongs to the Fur family
VCSRO51_2456	COG0166	Belongs to the GPI family
VCSRO51_2457	COG0432	Pfam Uncharacterised protein family UPF0047
VCSRO51_2458	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCSRO51_2461	COG0359	binds to the 23S rRNA
VCSRO51_2462	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
VCSRO51_2463	COG2965	DNA replication, synthesis of RNA primer
VCSRO51_2464	COG0360	Binds together with S18 to 16S ribosomal RNA
VCSRO51_2466	COG2906	2 iron, 2 sulfur cluster binding
VCSRO51_2467	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCSRO51_2468	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCSRO51_2469	COG0049	tRNA binding
VCSRO51_2472	COG2923	Belongs to the DsrF TusC family
VCSRO51_2473	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VCSRO51_2474	COG2964	Protein conserved in bacteria
VCSRO51_2475	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO51_2477	COG2900	Belongs to the SlyX family
VCSRO51_2478	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VCSRO51_2479	COG0330	HflC and HflK could
VCSRO51_2480	COG0330	HflC and HflK could
VCSRO51_2481	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VCSRO51_2482	COG1923	regulation of RNA biosynthetic process
VCSRO51_2483	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VCSRO51_2484	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VCSRO51_2486	COG0802	atpase or kinase
VCSRO51_2487	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VCSRO51_2497	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VCSRO51_2498	COG1162	GTPase activity
VCSRO51_2499	COG0688	phosphatidylethanolamine metabolic process
VCSRO51_2500	COG0471	metal ion transport
VCSRO51_2502	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VCSRO51_2503	COG4942	peptidase
VCSRO51_2506	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VCSRO51_2507	COG2816	NAD+ diphosphatase activity
VCSRO51_2508	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VCSRO51_2509	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VCSRO51_2510	COG0085	RNA polymerase activity
VCSRO51_2511	COG0222	ribosome binding
VCSRO51_2512	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VCSRO51_2514	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VCSRO51_2515	COG0250	Participates in transcription elongation, termination and antitermination
VCSRO51_2516	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCSRO51_2517	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCSRO51_2522	COG1072	(Pantothenic acid kinase))
VCSRO51_2524	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VCSRO51_2526	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VCSRO51_2535	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VCSRO51_2539	COG3118	belongs to the thioredoxin family
VCSRO51_2540	COG0513	Belongs to the DEAD box helicase family
VCSRO51_2541	COG0248	Ppx GppA phosphatase
VCSRO51_2542	COG2205	protein histidine kinase activity
VCSRO51_2542	COG0784	Response regulator, receiver
VCSRO51_2542	COG2198	Histidine kinase
VCSRO51_2544	COG2814	Major facilitator Superfamily
VCSRO51_2547	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCSRO51_2548	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VCSRO51_2549	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO51_2550	COG0439	Biotin carboxylase
VCSRO51_2551	COG2264	protein methyltransferase activity
VCSRO51_2552	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO51_2553	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VCSRO51_2554	COG1609	Transcriptional regulator
VCSRO51_2555	COG0129	dihydroxy-acid dehydratase activity
VCSRO51_2556	COG3265	gluconokinase activity
VCSRO51_2558	COG0800	Aldolase
VCSRO51_2561	COG0840	transmembrane signaling receptor activity
VCSRO51_2562	COG1982	Orn Lys Arg decarboxylase major
VCSRO51_2563	COG0531	amino acid
VCSRO51_2564	COG3710	Transcriptional regulator
VCSRO51_2565	COG0789	Transcriptional regulator
VCSRO51_2567	COG0151	Belongs to the GarS family
VCSRO51_2569	COG0776	regulation of translation
VCSRO51_2570	COG1253	flavin adenine dinucleotide binding
VCSRO51_2572	COG3068	Protein conserved in bacteria
VCSRO51_2574	COG1573	uracil-dna glycosylase
VCSRO51_2575	COG0668	transmembrane transport
VCSRO51_2578	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VCSRO51_2580	COG0367	asparagine synthase
VCSRO51_2581	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCSRO51_2583	COG0728	peptidoglycan biosynthetic process
VCSRO51_2586	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO51_2587	COG1083	cytidylyl-transferase
VCSRO51_2588	COG0673	inositol 2-dehydrogenase activity
VCSRO51_2591	COG2089	acid synthase
VCSRO51_2594	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VCSRO51_2595	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VCSRO51_2597	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
VCSRO51_2598	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCSRO51_2600	COG0110	maltose O-acetyltransferase activity
VCSRO51_2604	COG0859	PFAM glycosyl transferase family 9
VCSRO51_2606	COG1519	Transferase
VCSRO51_2611	COG3642	lipopolysaccharide core region biosynthetic process
VCSRO51_2612	COG0859	PFAM glycosyl transferase family 9
VCSRO51_2613	COG0463	Glycosyl transferase, family 2
VCSRO51_2614	COG0859	PFAM glycosyl transferase family 9
VCSRO51_2615	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VCSRO51_2616	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VCSRO51_2618	COG0267	Belongs to the bacterial ribosomal protein bL33 family
VCSRO51_2619	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VCSRO51_2620	COG2003	Belongs to the UPF0758 family
VCSRO51_2622	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VCSRO51_2623	COG1309	transcriptional regulator
VCSRO51_2624	COG1560	Kdo2-lipid A biosynthetic process
VCSRO51_2625	COG1560	Kdo2-lipid A biosynthetic process
VCSRO51_2626	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VCSRO51_2627	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VCSRO51_2628	COG1561	YicC-like family, N-terminal region
VCSRO51_2652	COG2801	Transposase and inactivated derivatives
VCSRO51_2668	COG2862	Uncharacterized protein family, UPF0114
VCSRO51_2670	COG1263	PTS System
VCSRO51_2670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO51_2671	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCSRO51_2674	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VCSRO51_2675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VCSRO51_2676	COG1120	ATPase activity
VCSRO51_2677	COG4774	siderophore transport
VCSRO51_2678	COG1132	(ABC) transporter
VCSRO51_2681	COG0514	ATP-dependent DNA helicase (RecQ)
VCSRO51_2682	COG2962	Rard protein
VCSRO51_2683	COG0405	Gamma-glutamyltransferase
VCSRO51_2685	COG1280	lysine exporter protein (LysE YggA)
VCSRO51_2686	COG0210	DNA helicase
VCSRO51_2688	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VCSRO51_2689	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO51_2691	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO51_2692	COG0601	transmembrane transport
VCSRO51_2693	COG0747	negative chemotaxis
VCSRO51_2702	COG1309	transcriptional regulator
VCSRO51_2703	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO51_2704	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO51_2705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO51_2706	COG2960	long-chain fatty acid transporting porin activity
VCSRO51_2707	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VCSRO51_2708	COG0583	DNA-binding transcription factor activity
VCSRO51_2716	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
VCSRO51_2717	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCSRO51_2718	COG1739	Uncharacterized protein family UPF0029
VCSRO51_2719	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCSRO51_2719	COG1024	Enoyl-CoA hydratase
VCSRO51_2720	COG0183	Belongs to the thiolase family
VCSRO51_2721	COG0583	DNA-binding transcription factor activity
VCSRO51_2722	COG2814	Major facilitator Superfamily
VCSRO51_2724	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VCSRO51_2725	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VCSRO51_2726	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VCSRO51_2727	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VCSRO51_2728	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VCSRO51_2729	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VCSRO51_2731	COG0356	it plays a direct role in the translocation of protons across the membrane
VCSRO51_2732	COG3312	ion transport
VCSRO51_2733	COG1475	DNA binding
VCSRO51_2734	COG1192	Involved in chromosome partitioning
VCSRO51_2735	COG0357	Ribosomal RNA small subunit methyltransferase G
VCSRO51_2736	COG0445	tRNA wobble uridine modification
VCSRO51_2741	COG0217	transcriptional regulatory protein
VCSRO51_2742	COG2084	Dehydrogenase
VCSRO51_2745	COG2909	trisaccharide binding
VCSRO51_2746	COG0058	SHG alpha-glucan phosphorylase activity
VCSRO51_2747	COG1640	4-alpha-glucanotransferase
VCSRO51_2748	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VCSRO51_2750	COG3501	Rhs element vgr protein
VCSRO51_2757	COG0471	metal ion transport
VCSRO51_2758	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCSRO51_2762	COG0840	transmembrane signaling receptor activity
VCSRO51_2766	COG0671	phosphoesterase, PA-phosphatase related
VCSRO51_2767	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VCSRO51_2769	COG1999	signal sequence binding
VCSRO51_2772	COG0786	glutamate:sodium symporter activity
VCSRO51_2779	COG0813	purine-nucleoside phosphorylase activity
VCSRO51_2780	COG3272	Protein of unknown function (DUF1722)
VCSRO51_2782	COG0415	Belongs to the DNA photolyase family
VCSRO51_2783	COG1388	LysM domain
VCSRO51_2783	COG1376	ErfK ybiS ycfS ynhG family protein
VCSRO51_2785	COG0513	Belongs to the DEAD box helicase family
VCSRO51_2786	COG1770	oligopeptidase
VCSRO51_2792	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCSRO51_2793	COG0573	inorganic phosphate transmembrane transporter activity
VCSRO51_2794	COG0581	inorganic phosphate transmembrane transporter activity
VCSRO51_2795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCSRO51_2798	COG3314	Sporulation integral membrane protein YlbJ
VCSRO51_2799	COG3314	Sporulation integral membrane protein YlbJ
VCSRO51_2800	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO51_2802	COG0739	heme binding
VCSRO51_2803	COG3300	MHYT domain
VCSRO51_2803	COG5001	Diguanylate cyclase
VCSRO51_2805	COG0583	DNA-binding transcription factor activity
VCSRO51_2806	COG2814	Major facilitator Superfamily
VCSRO51_2811	COG1301	dicarboxylic acid transport
VCSRO51_2813	COG1342	Belongs to the UPF0251 family
VCSRO51_2819	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VCSRO51_2820	COG0673	inositol 2-dehydrogenase activity
VCSRO51_2822	COG2200	EAL domain
VCSRO51_2822	COG2771	luxR family
VCSRO51_2823	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO51_2825	COG0564	pseudouridine synthase activity
VCSRO51_2838	COG3829	transcription factor binding
VCSRO51_2843	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO51_2843	COG3501	Rhs element vgr protein
VCSRO51_2847	COG1869	D-ribose catabolic process
VCSRO51_2848	COG1129	ABC transporter
VCSRO51_2849	COG1172	Belongs to the binding-protein-dependent transport system permease family
VCSRO51_2850	COG1879	ABC-type sugar transport system periplasmic component
VCSRO51_2851	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO51_2852	COG1609	Transcriptional regulator
VCSRO51_2857	COG0584	glycerophosphoryl diester phosphodiesterase
VCSRO51_2858	COG2271	Major facilitator Superfamily
VCSRO51_2865	COG0579	oxidoreductase
VCSRO51_2867	COG0242	peptide deformylase activity
VCSRO51_2870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO51_2871	COG1609	Transcriptional regulator
VCSRO51_2872	COG1017	nitric oxide dioxygenase activity
VCSRO51_2872	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCSRO51_2873	COG1320	monovalent cation:proton antiporter activity
VCSRO51_2874	COG2212	antiporter activity
VCSRO51_2875	COG1863	multisubunit Na H antiporter MnhE subunit
VCSRO51_2876	COG0651	ATP synthesis coupled electron transport
VCSRO51_2877	COG1006	Multisubunit Na H antiporter MnhC subunit
VCSRO51_2878	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCSRO51_2878	COG2111	Na H antiporter
VCSRO51_2880	COG0589	response to stress
VCSRO51_2881	COG0814	amino acid
VCSRO51_2884	COG3530	Putative quorum-sensing-regulated virulence factor
VCSRO51_2886	COG5002	protein histidine kinase activity
VCSRO51_2886	COG5001	Diguanylate cyclase
VCSRO51_2887	COG1278	Cold shock
VCSRO51_2890	COG2304	oxidoreductase activity
VCSRO51_2894	COG0714	Associated with various cellular activities
VCSRO51_2895	COG0840	transmembrane signaling receptor activity
VCSRO51_2898	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO51_2899	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO51_2901	COG3604	Transcriptional regulator
VCSRO51_2902	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCSRO51_2902	COG1017	nitric oxide dioxygenase activity
VCSRO51_2903	COG1278	Cold shock
VCSRO51_2904	COG3036	rescue of stalled ribosome
VCSRO51_2909	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VCSRO51_2909	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VCSRO51_2910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCSRO51_2912	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCSRO51_2914	COG0516	GMP reductase activity
VCSRO51_2921	COG1175	transmembrane transport
VCSRO51_2922	COG0395	ABC-type sugar transport system, permease component
VCSRO51_2923	COG5578	integral membrane protein
VCSRO51_2926	COG1609	Transcriptional regulator
VCSRO51_2928	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
VCSRO51_2929	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
VCSRO51_2930	COG4580	involved in the transport of maltose and maltodextrins
VCSRO51_2931	COG0840	transmembrane signaling receptor activity
VCSRO51_2932	COG1482	cell wall glycoprotein biosynthetic process
VCSRO51_2936	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
VCSRO51_2937	COG3385	transposase activity
VCSRO51_2940	COG0513	Belongs to the DEAD box helicase family
VCSRO51_2941	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCSRO51_2942	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VCSRO51_2943	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VCSRO51_2944	COG3437	response regulator, receiver
VCSRO51_2944	COG0784	Response regulator, receiver
VCSRO51_2945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO51_2945	COG4191	Histidine kinase
VCSRO51_2947	COG1757	Na H antiporter
VCSRO51_2948	COG2814	Major facilitator Superfamily
VCSRO51_2950	COG3706	GGDEF domain
VCSRO51_2951	COG3240	lipase activity
VCSRO51_2954	COG0840	transmembrane signaling receptor activity
VCSRO51_2955	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VCSRO51_2956	COG5380	lipid catabolic process
VCSRO51_2961	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO51_2962	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO51_2963	COG4605	iron ion homeostasis
VCSRO51_2964	COG4604	ABC transporter, ATP-binding protein
VCSRO51_2965	COG2207	Transcriptional regulator
VCSRO51_2968	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCSRO51_2975	COG0745	RESPONSE REGULATOR receiver
VCSRO51_2977	COG3623	hexulose-6-phosphate isomerase
VCSRO51_2978	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
VCSRO51_2979	COG0561	phosphatase activity
VCSRO51_2989	COG0745	RESPONSE REGULATOR receiver
VCSRO51_2990	COG5002	protein histidine kinase activity
VCSRO51_2993	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO51_3000	COG1686	Belongs to the peptidase S11 family
VCSRO51_3005	COG3385	transposase activity
VCSRO51_3006	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCSRO51_3006	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCSRO51_3007	COG0509	glycine decarboxylation via glycine cleavage system
VCSRO51_3008	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCSRO51_3010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VCSRO51_3013	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VCSRO51_3014	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
VCSRO51_3023	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO51_3031	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO51_3036	COG2161	toxin-antitoxin pair type II binding
VCSRO51_3037	COG4115	mRNA cleavage
VCSRO51_3049	COG5433	transposase activity
VCSRO51_3062	COG3549	Plasmid maintenance system killer
VCSRO51_3063	COG3093	addiction module antidote protein HigA
VCSRO51_3068	COG2801	Transposase and inactivated derivatives
VCSRO51_3073	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO51_3080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO51_3092	COG1619	proteins homologs of microcin C7 resistance protein MccF
VCSRO51_3104	COG1328	CTP reductase activity
VCSRO51_3105	COG0602	queuosine metabolic process
VCSRO51_3107	COG0189	ligase activity
VCSRO51_3107	COG4067	protein conserved in archaea
VCSRO51_3108	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO51_3108	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO51_3108	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VCSRO51_3109	COG1105	Belongs to the carbohydrate kinase PfkB family
VCSRO51_3110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO51_3110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO51_3111	COG1609	Transcriptional regulator
VCSRO51_3112	COG0420	3'-5' exonuclease activity
VCSRO51_3113	COG0419	ATPase involved in DNA repair
VCSRO51_3114	COG0784	Response regulator, receiver
VCSRO51_3114	COG2205	protein histidine kinase activity
VCSRO51_3115	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO51_3117	COG0038	chloride channel
VCSRO51_3118	COG0523	cobalamin synthesis protein
VCSRO51_3121	COG2200	EAL domain
VCSRO51_3123	COG3038	cytochrome b561
VCSRO51_3125	COG2116	formate transmembrane transporter activity
VCSRO51_3126	COG0583	DNA-binding transcription factor activity
VCSRO51_3128	COG3593	DNA synthesis involved in DNA repair
VCSRO51_3129	COG0737	Belongs to the 5'-nucleotidase family
VCSRO51_3132	COG2824	Alkylphosphonate utilization operon protein PhnA
VCSRO51_3138	COG2199	diguanylate cyclase activity
VCSRO51_3142	COG3706	GGDEF domain
VCSRO51_3145	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VCSRO51_3146	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VCSRO51_3148	COG0745	RESPONSE REGULATOR receiver
VCSRO51_3151	COG3140	Belongs to the UPF0181 family
VCSRO51_3153	COG0023	Translation Initiation Factor
VCSRO51_3157	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO51_3157	COG1042	CoA-binding domain protein
VCSRO51_3157	COG0045	succinate-CoA ligase (ADP-forming) activity
VCSRO51_3158	COG0583	DNA-binding transcription factor activity
VCSRO51_3159	COG1629	transport
VCSRO51_3159	COG4771	TonB-dependent receptor
VCSRO51_3162	COG2050	protein possibly involved in aromatic compounds catabolism
VCSRO51_3166	COG0625	glutathione transferase activity
VCSRO51_3169	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VCSRO51_3170	COG4172	Belongs to the ABC transporter superfamily
VCSRO51_3171	COG4239	(ABC) transporter, permease
VCSRO51_3172	COG4174	ABC transporter (Permease)
VCSRO51_3173	COG4166	transmembrane transport
VCSRO51_3180	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCSRO51_3181	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO51_3182	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO51_3184	COG3842	ATPase activity
VCSRO51_3186	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO51_3189	COG1175	transmembrane transport
VCSRO51_3190	COG3833	ABC-type maltose transport systems, permease component
VCSRO51_3194	COG1011	Hydrolase
VCSRO51_3196	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VCSRO51_3197	COG1970	mechanosensitive ion channel activity
VCSRO51_3198	COG2759	Belongs to the formate--tetrahydrofolate ligase family
VCSRO51_3199	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO51_3199	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO51_3200	COG0302	gtp cyclohydrolase
VCSRO51_3202	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCSRO51_3204	COG2897	thiosulfate sulfurtransferase activity
VCSRO51_3205	COG2390	Transcriptional regulator
VCSRO51_3207	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCSRO51_3213	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO51_3218	COG0583	DNA-binding transcription factor activity
VCSRO51_3219	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
VCSRO51_3227	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCSRO51_3237	COG1263	PTS System
VCSRO51_3237	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO51_3238	COG1609	Transcriptional regulator
VCSRO51_3239	COG1621	beta-fructofuranosidase activity
VCSRO51_3240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO51_3241	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCSRO51_3244	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO51_3245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO51_3246	COG0840	transmembrane signaling receptor activity
VCSRO51_3247	COG3069	C4-dicarboxylate transmembrane transporter activity
VCSRO51_3248	COG1760	l-serine dehydratase
VCSRO51_3249	COG2197	response regulator
VCSRO51_3250	COG3850	Histidine kinase
VCSRO51_3251	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCSRO51_3253	COG0243	molybdopterin cofactor binding
VCSRO51_3257	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO51_3258	COG2197	response regulator
VCSRO51_3259	COG3851	Histidine kinase
VCSRO51_3260	COG2271	Major facilitator Superfamily
VCSRO51_3261	COG1840	ABC-type Fe3 transport system, periplasmic component
VCSRO51_3263	COG3842	ATPase activity
VCSRO51_3264	COG3243	poly(R)-hydroxyalkanoic acid synthase
VCSRO51_3266	COG0183	Belongs to the thiolase family
VCSRO51_3268	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO51_3269	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO51_3273	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCSRO51_3275	COG1979	alcohol dehydrogenase
VCSRO51_3278	COG4191	Histidine kinase
VCSRO51_3280	COG2271	Major facilitator Superfamily
VCSRO51_3281	COG0469	pyruvate kinase activity
VCSRO51_3282	COG2198	Histidine kinase
VCSRO51_3282	COG2205	protein histidine kinase activity
VCSRO51_3282	COG0784	Response regulator, receiver
VCSRO51_3283	COG1879	ABC-type sugar transport system periplasmic component
VCSRO51_3284	COG1803	Methylglyoxal synthase
VCSRO51_3285	COG1335	isochorismatase
VCSRO51_3286	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VCSRO51_3287	COG0210	DNA helicase
VCSRO51_3288	COG1289	transmembrane transporter activity
VCSRO51_3295	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
VCSRO51_3296	COG4149	molybdate abc transporter
VCSRO51_3297	COG0725	ABC transporter, periplasmic molybdate-binding protein
VCSRO51_3298	COG1492	cobalamin metabolic process
VCSRO51_3307	COG5002	protein histidine kinase activity
VCSRO51_3307	COG0784	Response regulator, receiver
VCSRO51_3308	COG1879	ABC-type sugar transport system periplasmic component
VCSRO51_3310	COG2827	Endonuclease containing a URI domain
VCSRO51_3311	COG3132	Protein of unknown function, DUF480
VCSRO51_3313	COG2926	Belongs to the UPF0265 family
VCSRO51_3316	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
VCSRO51_3317	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VCSRO51_3318	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCSRO51_3319	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
VCSRO51_3320	COG0247	lactate metabolic process
VCSRO51_3321	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCSRO51_3322	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCSRO51_3323	COG3118	belongs to the thioredoxin family
VCSRO51_3328	COG4160	amino acid transport
VCSRO51_3329	COG4215	(ABC) transporter
VCSRO51_3330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO51_3331	COG1126	abc transporter atp-binding protein
VCSRO51_3333	COG2425	protein containing a von Willebrand factor type A (vWA) domain
VCSRO51_3335	COG0494	nUDIX hydrolase
VCSRO51_3336	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VCSRO51_3338	COG1309	transcriptional regulator
VCSRO51_3339	COG0513	Belongs to the DEAD box helicase family
VCSRO51_3340	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
VCSRO51_3342	COG0814	amino acid
VCSRO51_3343	COG0840	transmembrane signaling receptor activity
VCSRO51_3344	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VCSRO51_3345	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
VCSRO51_3347	COG1984	allophanate hydrolase subunit 2
VCSRO51_3350	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VCSRO51_3351	COG4181	ATPase activity
VCSRO51_3353	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCSRO51_3354	COG1716	ATPase activity
VCSRO51_3354	COG5001	Diguanylate cyclase
VCSRO51_3356	COG0484	heat shock protein binding
VCSRO51_3360	COG0546	phosphoglycolate phosphatase activity
VCSRO51_3363	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO51_3365	COG0513	Belongs to the DEAD box helicase family
VCSRO51_3368	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCSRO51_3370	COG3046	protein related to deoxyribodipyrimidine photolyase
VCSRO51_3371	COG3397	chitin binding
VCSRO51_3375	COG1166	arginine decarboxylase activity
VCSRO51_3377	COG2239	Acts as a magnesium transporter
VCSRO51_3378	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCSRO51_3379	COG0459	protein refolding
VCSRO51_3381	COG0527	aspartate kinase activity
VCSRO51_3382	COG0662	Cupin 2, conserved barrel domain protein
VCSRO51_3383	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VCSRO51_3384	COG0456	acetyltransferase
VCSRO51_3385	COG2154	pterin-4-alpha-carbinolamine dehydratase
VCSRO51_3386	COG3186	Phenylalanine-4-hydroxylase
VCSRO51_3387	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCSRO51_3390	COG2264	protein methyltransferase activity
VCSRO51_3396	COG1253	flavin adenine dinucleotide binding
VCSRO51_3397	COG1765	OsmC-like protein
VCSRO51_3402	COG0531	amino acid
VCSRO51_3405	COG4989	oxidoreductase activity
VCSRO51_3406	COG0366	Alpha amylase catalytic
VCSRO51_3407	COG2067	long-chain fatty acid transport protein
VCSRO51_3408	COG2267	carboxylic ester hydrolase activity
VCSRO51_3410	COG3227	Zinc metalloprotease (Elastase)
VCSRO51_3411	COG3047	cAMP biosynthetic process
VCSRO51_3414	COG1686	Belongs to the peptidase S11 family
VCSRO51_3415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VCSRO51_3416	COG1271	oxidase subunit
VCSRO51_3417	COG1294	oxidase, subunit
VCSRO51_3420	COG3048	D-serine ammonia-lyase activity
VCSRO51_3421	COG0583	DNA-binding transcription factor activity
VCSRO51_3423	COG0582	viral genome integration into host DNA
VCSRO51_3430	COG1063	alcohol dehydrogenase
VCSRO51_3431	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO51_3432	COG2873	o-acetylhomoserine
VCSRO51_3434	COG0346	lactoylglutathione lyase activity
VCSRO51_3438	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
VCSRO51_3439	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO51_3440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VCSRO51_3441	COG0363	glucosamine-6-phosphate deaminase activity
VCSRO51_3442	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VCSRO51_3447	COG1929	Belongs to the glycerate kinase type-1 family
VCSRO51_3449	COG0748	coenzyme F420 binding
VCSRO51_3450	COG3721	Heme iron utilization protein
VCSRO51_3452	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCSRO51_3453	COG0811	peptide transport
VCSRO51_3454	COG0848	biopolymer transport protein
VCSRO51_3455	COG4558	Periplasmic binding protein
VCSRO51_3456	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO51_3457	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VCSRO51_3464	COG0633	Ferredoxin
VCSRO51_3464	COG0633	Ferredoxin
VCSRO51_3464	COG3217	Mosc domain protein beta barrel domain protein
VCSRO51_3464	COG3217	Mosc domain protein beta barrel domain protein
VCSRO51_3465	COG0418	dihydroorotase activity
VCSRO51_3467	COG3152	Membrane
VCSRO51_3469	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCSRO51_3470	COG2354	Protein conserved in bacteria
VCSRO51_3471	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO51_3472	COG1278	Cold shock
VCSRO51_3477	COG2199	diguanylate cyclase activity
VCSRO51_3478	COG2199	diguanylate cyclase activity
VCSRO51_3479	COG1349	DNA-binding transcription factor activity
VCSRO51_3482	COG3833	ABC-type maltose transport systems, permease component
VCSRO51_3483	COG1175	transmembrane transport
VCSRO51_3485	COG3842	ATPase activity
VCSRO51_3486	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO51_3489	COG0393	Putative heavy-metal-binding
VCSRO51_3491	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO51_3492	COG0835	chemotaxis
VCSRO51_3492	COG0784	Response regulator, receiver
VCSRO51_3493	COG1846	Transcriptional regulator
VCSRO51_3494	COG3706	GGDEF domain
VCSRO51_3501	COG0583	DNA-binding transcription factor activity
VCSRO51_3502	COG5001	Diguanylate cyclase
VCSRO51_3504	COG1741	Belongs to the pirin family
VCSRO51_3505	COG3123	guanosine phosphorylase activity
VCSRO51_3507	COG2211	Major facilitator Superfamily
VCSRO51_3508	COG0840	transmembrane signaling receptor activity
VCSRO51_3509	COG1067	ATP-dependent peptidase activity
VCSRO51_3511	COG4172	Belongs to the ABC transporter superfamily
VCSRO51_3516	COG0583	DNA-binding transcription factor activity
VCSRO51_3518	COG1620	l-lactate permease
VCSRO51_3521	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
VCSRO51_3523	COG0840	transmembrane signaling receptor activity
VCSRO51_3525	COG0513	Belongs to the DEAD box helicase family
VCSRO51_3527	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
VCSRO51_3529	COG1132	(ABC) transporter
VCSRO51_3531	COG1902	pentaerythritol trinitrate reductase activity
VCSRO51_3533	COG1280	lysine exporter protein (LysE YggA)
VCSRO51_3534	COG2207	Transcriptional regulator
VCSRO51_3538	COG1846	Transcriptional regulator
VCSRO51_3539	COG1764	response to oxidative stress
VCSRO51_3540	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCSRO51_3541	COG0697	spore germination
VCSRO51_3543	COG0700	Nucleoside recognition
VCSRO51_3544	COG3366	ferrous iron transmembrane transporter activity
VCSRO51_3545	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
VCSRO51_3547	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VCSRO51_3548	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
VCSRO51_3549	COG2259	Doxx family
VCSRO51_3554	COG0363	glucosamine-6-phosphate deaminase activity
VCSRO51_3557	COG4580	involved in the transport of maltose and maltodextrins
VCSRO51_3560	COG0840	transmembrane signaling receptor activity
VCSRO51_3562	COG0840	transmembrane signaling receptor activity
VCSRO51_3565	COG2801	Transposase and inactivated derivatives
VCSRO51_3566	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO51_3567	COG1126	abc transporter atp-binding protein
VCSRO51_3569	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO51_3570	COG4597	amino acid ABC transporter
VCSRO51_3571	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCSRO51_3572	COG2213	PTS system mannitol-specific
VCSRO51_3572	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO51_3573	COG0246	Mannitol dehydrogenase
VCSRO51_3574	COG3722	fumarate hydratase activity
VCSRO51_3575	COG0673	inositol 2-dehydrogenase activity
VCSRO51_3581	COG2910	NAD(P)H-binding
VCSRO51_3583	COG0840	transmembrane signaling receptor activity
VCSRO51_3584	COG4221	oxidoreductase activity
VCSRO51_3586	COG1901	pseudouridine methyltransferase
VCSRO51_3588	COG0531	amino acid
VCSRO51_3589	COG1982	Orn Lys Arg decarboxylase major
VCSRO51_3594	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCSRO51_3599	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VCSRO51_3607	COG0745	RESPONSE REGULATOR receiver
VCSRO51_3613	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCSRO51_3614	COG0840	transmembrane signaling receptor activity
VCSRO51_3615	COG0835	chemotaxis
VCSRO51_3616	COG0835	chemotaxis
VCSRO51_3617	COG0643	Histidine kinase
VCSRO51_3617	COG2198	Histidine kinase
VCSRO51_3621	COG0601	transmembrane transport
VCSRO51_3622	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO51_3624	COG2194	sulfuric ester hydrolase activity
VCSRO51_3625	COG0642	Histidine kinase
VCSRO51_3632	COG1444	tRNA N-acetyltransferase activity
VCSRO51_3633	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine