locus-tag	class	description
VCSRO63_0001	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCSRO63_0008	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VCSRO63_0018	COG4974	Belongs to the 'phage' integrase family
VCSRO63_0019	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
VCSRO63_0020	COG0706	membrane insertase activity
VCSRO63_0021	COG0594	ribonuclease P activity
VCSRO63_0022	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VCSRO63_0023	COG1126	abc transporter atp-binding protein
VCSRO63_0026	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VCSRO63_0027	COG0592	DNA-directed DNA polymerase activity
VCSRO63_0028	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VCSRO63_0029	COG0187	DNA topoisomerase II activity
VCSRO63_0032	COG0071	Belongs to the small heat shock protein (HSP20) family
VCSRO63_0033	COG3977	Valine--pyruvate aminotransferase
VCSRO63_0034	COG0751	glycine-tRNA ligase activity
VCSRO63_0035	COG0752	glycyl-tRNA synthetase alpha subunit
VCSRO63_0036	COG2119	membrane
VCSRO63_0038	COG0425	Belongs to the sulfur carrier protein TusA family
VCSRO63_0040	COG0604	alcohol dehydrogenase
VCSRO63_0042	COG0129	dihydroxy-acid dehydratase activity
VCSRO63_0043	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCSRO63_0046	COG0606	chelatase, subunit chli
VCSRO63_0047	COG0204	Acyl-transferase
VCSRO63_0048	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCSRO63_0049	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VCSRO63_0051	COG3084	Protein conserved in bacteria
VCSRO63_0052	COG4326	sporulation control protein
VCSRO63_0053	COG1272	protein, Hemolysin III
VCSRO63_0055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCSRO63_0056	COG0569	domain protein
VCSRO63_0057	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VCSRO63_0057	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCSRO63_0058	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VCSRO63_0059	COG0242	peptide deformylase activity
VCSRO63_0060	COG1652	LysM domain
VCSRO63_0061	COG0758	DNA mediated transformation
VCSRO63_0062	COG2922	Belongs to the Smg family
VCSRO63_0063	COG0551	DNA topoisomerase type I activity
VCSRO63_0064	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VCSRO63_0065	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VCSRO63_0066	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO63_0067	COG0408	coproporphyrinogen oxidase activity
VCSRO63_0068	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VCSRO63_0070	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VCSRO63_0077	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VCSRO63_0078	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VCSRO63_0080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCSRO63_0081	COG2104	thiamine diphosphate biosynthetic process
VCSRO63_0082	COG2022	thiamine diphosphate biosynthetic process
VCSRO63_0083	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCSRO63_0084	COG0006	proline dipeptidase activity
VCSRO63_0084	COG0006	proline dipeptidase activity
VCSRO63_0088	COG1522	sequence-specific DNA binding
VCSRO63_0089	COG5001	Diguanylate cyclase
VCSRO63_0089	COG5002	protein histidine kinase activity
VCSRO63_0093	COG0589	response to stress
VCSRO63_0094	COG1528	Iron-storage protein
VCSRO63_0096	COG2081	HI0933 family
VCSRO63_0098	COG1322	Protein conserved in bacteria
VCSRO63_0099	COG2226	methyltransferase
VCSRO63_0102	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO63_0103	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO63_0104	COG0805	protein transport
VCSRO63_0105	COG0534	Mate efflux family protein
VCSRO63_0107	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VCSRO63_0108	COG2937	Belongs to the GPAT DAPAT family
VCSRO63_0109	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VCSRO63_0110	COG3161	chorismate lyase activity
VCSRO63_0111	COG1580	Controls the rotational direction of flagella during chemotaxis
VCSRO63_0112	COG0840	transmembrane signaling receptor activity
VCSRO63_0114	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO63_0115	COG0084	hydrolase, TatD family'
VCSRO63_0118	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO63_0118	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO63_0122	COG3078	GTPase activator activity
VCSRO63_0125	COG3071	HemY protein
VCSRO63_0126	COG2959	enzyme of heme biosynthesis
VCSRO63_0127	COG1587	Uroporphyrinogen-III synthase
VCSRO63_0128	COG0181	hydroxymethylbilane synthase activity
VCSRO63_0130	COG1965	Belongs to the frataxin family
VCSRO63_0131	COG0019	diaminopimelate decarboxylase activity
VCSRO63_0132	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VCSRO63_0134	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VCSRO63_0135	COG1011	Hydrolase
VCSRO63_0136	COG3287	FIST C domain
VCSRO63_0136	COG2199	diguanylate cyclase activity
VCSRO63_0136	COG2200	EAL domain
VCSRO63_0139	COG0561	phosphatase activity
VCSRO63_0140	COG2267	carboxylic ester hydrolase activity
VCSRO63_0141	COG1280	lysine exporter protein (LysE YggA)
VCSRO63_0142	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCSRO63_0143	COG0783	Belongs to the Dps family
VCSRO63_0148	COG0742	ribosomal rna small subunit methyltransferase
VCSRO63_0149	COG0552	protein localization to endoplasmic reticulum
VCSRO63_0150	COG2884	Cell division ATP-binding protein ftsE
VCSRO63_0151	COG2177	Part of the ABC transporter FtsEX involved in
VCSRO63_0152	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCSRO63_0153	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO63_0156	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCSRO63_0158	COG1404	Belongs to the peptidase S8 family
VCSRO63_0159	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
VCSRO63_0173	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VCSRO63_0174	COG5001	Diguanylate cyclase
VCSRO63_0174	COG3300	MHYT domain
VCSRO63_0176	COG3852	Histidine kinase
VCSRO63_0178	COG0174	glutamine synthetase
VCSRO63_0180	COG1217	gtp-binding protein TYPA
VCSRO63_0182	COG1295	ribonuclease BN
VCSRO63_0183	COG1490	D-aminoacyl-tRNA deacylase activity
VCSRO63_0184	COG0456	acetyltransferase
VCSRO63_0186	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
VCSRO63_0187	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VCSRO63_0188	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VCSRO63_0189	COG3031	protein transport across the cell outer membrane
VCSRO63_0191	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO63_0192	COG1459	type II secretion system
VCSRO63_0193	COG2165	general secretion pathway protein
VCSRO63_0194	COG2165	general secretion pathway protein
VCSRO63_0195	COG2165	general secretion pathway protein
VCSRO63_0196	COG4795	General secretion pathway protein
VCSRO63_0197	COG3156	type II secretion system protein K
VCSRO63_0198	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCSRO63_0199	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCSRO63_0201	COG1218	3'(2'),5'-bisphosphate nucleotidase
VCSRO63_0202	COG0494	nUDIX hydrolase
VCSRO63_0204	COG1040	competence protein
VCSRO63_0205	COG0596	Alpha beta hydrolase
VCSRO63_0207	COG2183	response to ionizing radiation
VCSRO63_0208	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO63_0209	COG2199	diguanylate cyclase activity
VCSRO63_0212	COG2233	PERMEase
VCSRO63_0213	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VCSRO63_0214	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCSRO63_0215	COG1758	RNA polymerase activity
VCSRO63_0216	COG0194	GDP metabolic process
VCSRO63_0217	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VCSRO63_0218	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCSRO63_0222	COG4232	protein-disulfide reductase activity
VCSRO63_0224	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCSRO63_0225	COG1027	Aspartate ammonia-lyase
VCSRO63_0226	COG3706	GGDEF domain
VCSRO63_0227	COG3030	protein affecting phage T7 exclusion by the F plasmid
VCSRO63_0228	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VCSRO63_0230	COG2205	protein histidine kinase activity
VCSRO63_0231	COG0745	RESPONSE REGULATOR receiver
VCSRO63_0233	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VCSRO63_0234	COG0205	6-phosphofructokinase activity
VCSRO63_0235	COG1494	fructose-1,6-bisphosphatase
VCSRO63_0236	COG3074	FtsZ-dependent cytokinesis
VCSRO63_0237	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VCSRO63_0238	COG0460	homoserine dehydrogenase
VCSRO63_0238	COG0527	aspartate kinase activity
VCSRO63_0239	COG0626	cystathionine gamma-synthase activity
VCSRO63_0240	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
VCSRO63_0241	COG0281	malic enzyme
VCSRO63_0242	COG0254	rRNA binding
VCSRO63_0243	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VCSRO63_0244	COG1609	Transcriptional regulator
VCSRO63_0245	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCSRO63_0246	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VCSRO63_0247	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VCSRO63_0248	COG1575	Belongs to the MenA family. Type 1 subfamily
VCSRO63_0249	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCSRO63_0250	COG0534	Mate efflux family protein
VCSRO63_0251	COG0149	triose-phosphate isomerase activity
VCSRO63_0256	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCSRO63_0257	COG0459	protein refolding
VCSRO63_0262	COG1509	lysine 2,3-aminomutase activity
VCSRO63_0263	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCSRO63_0265	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VCSRO63_0266	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VCSRO63_0267	COG1053	succinate dehydrogenase
VCSRO63_0268	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VCSRO63_0269	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO63_0270	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VCSRO63_0271	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VCSRO63_0272	COG1045	serine acetyltransferase
VCSRO63_0274	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VCSRO63_0275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VCSRO63_0276	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VCSRO63_0277	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCSRO63_0278	COG0137	argininosuccinate synthase activity
VCSRO63_0279	COG0165	Argininosuccinate lyase
VCSRO63_0281	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO63_0282	COG0678	peroxiredoxin activity
VCSRO63_0282	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCSRO63_0284	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VCSRO63_0290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VCSRO63_0291	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VCSRO63_0293	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VCSRO63_0294	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VCSRO63_0295	COG0546	phosphoglycolate phosphatase activity
VCSRO63_0296	COG0180	Tryptophanyl-tRNA synthetase
VCSRO63_0299	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCSRO63_0301	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VCSRO63_0303	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO63_0306	COG3954	Phosphoribulokinase
VCSRO63_0308	COG0429	hydrolase of the alpha beta-hydrolase fold
VCSRO63_0310	COG0488	(ABC) transporter
VCSRO63_0311	COG2249	NAD(P)H dehydrogenase (quinone) activity
VCSRO63_0314	COG1047	Peptidyl-prolyl cis-trans
VCSRO63_0316	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VCSRO63_0317	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VCSRO63_0318	COG3083	sulfuric ester hydrolase activity
VCSRO63_0319	COG0557	exoribonuclease II activity
VCSRO63_0320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCSRO63_0321	COG0051	transcription antitermination factor activity, RNA binding
VCSRO63_0322	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VCSRO63_0323	COG0088	Forms part of the polypeptide exit tunnel
VCSRO63_0324	COG0089	rRNA binding
VCSRO63_0325	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VCSRO63_0326	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VCSRO63_0327	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VCSRO63_0328	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VCSRO63_0329	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VCSRO63_0330	COG0255	Belongs to the universal ribosomal protein uL29 family
VCSRO63_0331	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VCSRO63_0332	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VCSRO63_0333	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VCSRO63_0334	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VCSRO63_0335	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VCSRO63_0336	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VCSRO63_0338	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VCSRO63_0339	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VCSRO63_0340	COG1841	ribosomal large subunit assembly
VCSRO63_0342	COG0201	protein transport
VCSRO63_0343	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCSRO63_0344	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VCSRO63_0345	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VCSRO63_0346	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VCSRO63_0347	COG0202	RNA polymerase activity
VCSRO63_0348	COG0203	ribosomal protein L17
VCSRO63_0350	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO63_0351	COG3266	domain, Protein
VCSRO63_0351	COG3061	Opacity-associated protein A
VCSRO63_0352	COG0697	spore germination
VCSRO63_0353	COG2153	protein acetylation
VCSRO63_0354	COG0513	Belongs to the DEAD box helicase family
VCSRO63_0356	COG0737	Belongs to the 5'-nucleotidase family
VCSRO63_0357	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VCSRO63_0357	COG1648	precorrin-2 dehydrogenase activity
VCSRO63_0358	COG0175	sulfate reduction
VCSRO63_0359	COG2895	sulfate adenylyltransferase (ATP) activity
VCSRO63_0360	COG0529	Catalyzes the synthesis of activated sulfate
VCSRO63_0364	COG1136	(ABC) transporter
VCSRO63_0367	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VCSRO63_0368	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO63_0369	COG0729	surface antigen
VCSRO63_0371	COG2105	PFAM AIG2 family protein
VCSRO63_0372	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VCSRO63_0374	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCSRO63_0375	COG0163	prenyltransferase activity
VCSRO63_0377	COG1178	ABC-type Fe3 transport system permease component
VCSRO63_0378	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VCSRO63_0379	COG3028	Belongs to the UPF0307 family
VCSRO63_0380	COG0312	modulator of DNA gyrase
VCSRO63_0381	COG2239	Acts as a magnesium transporter
VCSRO63_0382	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO63_0383	COG1660	Displays ATPase and GTPase activities
VCSRO63_0384	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO63_0385	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCSRO63_0387	COG1137	ATPase activity
VCSRO63_0388	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VCSRO63_0391	COG0517	IMP dehydrogenase activity
VCSRO63_0391	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VCSRO63_0393	COG1127	ABC transporter
VCSRO63_0394	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VCSRO63_0395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCSRO63_0396	COG2854	intermembrane phospholipid transfer
VCSRO63_0398	COG5007	Belongs to the BolA IbaG family
VCSRO63_0399	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VCSRO63_0401	COG0251	oxidation-reduction process
VCSRO63_0403	COG0540	Belongs to the ATCase OTCase family
VCSRO63_0405	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VCSRO63_0406	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VCSRO63_0407	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VCSRO63_0408	COG0564	pseudouridine synthase activity
VCSRO63_0409	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCSRO63_0410	COG0525	valine-tRNA ligase activity
VCSRO63_0411	COG2927	DNA polymerase III (CHI subunit)
VCSRO63_0412	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCSRO63_0413	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCSRO63_0414	COG0795	lipopolysaccharide-transporting ATPase activity
VCSRO63_0415	COG0795	lipopolysaccharide-transporting ATPase activity
VCSRO63_0418	COG3437	response regulator, receiver
VCSRO63_0427	COG0066	3-isopropylmalate dehydratase activity
VCSRO63_0428	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
VCSRO63_0429	COG0473	3-isopropylmalate dehydrogenase activity
VCSRO63_0434	COG0583	DNA-binding transcription factor activity
VCSRO63_0435	COG0583	DNA-binding transcription factor activity
VCSRO63_0436	COG1022	Amp-dependent synthetase and ligase
VCSRO63_0437	COG0028	Belongs to the TPP enzyme family
VCSRO63_0438	COG0440	acetolactate synthase activity
VCSRO63_0439	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO63_0440	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VCSRO63_0441	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VCSRO63_0442	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VCSRO63_0443	COG3079	Belongs to the UPF0149 family
VCSRO63_0444	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO63_0445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO63_0448	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VCSRO63_0450	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VCSRO63_0451	COG1595	DNA-templated transcription, initiation
VCSRO63_0454	COG3086	response to oxidative stress
VCSRO63_0455	COG0481	GTPase activity
VCSRO63_0457	COG0571	ribonuclease III activity
VCSRO63_0458	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VCSRO63_0459	COG1381	Involved in DNA repair and RecF pathway recombination
VCSRO63_0460	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VCSRO63_0466	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCSRO63_0467	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCSRO63_0468	COG3956	TIGRFAM MazG family protein
VCSRO63_0469	COG0504	CTP synthase activity
VCSRO63_0470	COG0148	phosphopyruvate hydratase activity
VCSRO63_0471	COG0617	tRNA 3'-terminal CCA addition
VCSRO63_0472	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO63_0472	COG3267	Type II secretory pathway component ExeA
VCSRO63_0474	COG4991	sh3 domain protein
VCSRO63_0475	COG0306	phosphate transporter
VCSRO63_0476	COG1392	Phosphate transport regulator
VCSRO63_0477	COG3025	triphosphatase activity
VCSRO63_0479	COG0840	transmembrane signaling receptor activity
VCSRO63_0480	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VCSRO63_0482	COG1538	Outer membrane efflux protein
VCSRO63_0483	COG0494	nUDIX hydrolase
VCSRO63_0484	COG3151	Protein conserved in bacteria
VCSRO63_0486	COG3150	esterase
VCSRO63_0487	COG0187	DNA topoisomerase II activity
VCSRO63_0488	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VCSRO63_0490	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VCSRO63_0491	COG0237	dephospho-CoA kinase activity
VCSRO63_0493	COG1459	type II secretion system
VCSRO63_0494	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO63_0498	COG0716	FMN binding
VCSRO63_0499	COG4974	Belongs to the 'phage' integrase family
VCSRO63_0500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCSRO63_0501	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VCSRO63_0502	COG0737	Belongs to the 5'-nucleotidase family
VCSRO63_0503	COG2186	Transcriptional regulator
VCSRO63_0504	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VCSRO63_0505	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCSRO63_0506	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO63_0508	COG3116	cell division
VCSRO63_0509	COG0768	penicillin binding
VCSRO63_0510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VCSRO63_0511	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VCSRO63_0513	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VCSRO63_0514	COG0772	Belongs to the SEDS family
VCSRO63_0515	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
VCSRO63_0516	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCSRO63_0517	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VCSRO63_0518	COG0849	cell division
VCSRO63_0519	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VCSRO63_0520	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VCSRO63_0522	COG0653	protein targeting
VCSRO63_0523	COG0494	nUDIX hydrolase
VCSRO63_0524	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
VCSRO63_0526	COG0505	Belongs to the CarA family
VCSRO63_0527	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VCSRO63_0530	COG0730	response to heat
VCSRO63_0531	COG0583	DNA-binding transcription factor activity
VCSRO63_0532	COG2860	membrane
VCSRO63_0533	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VCSRO63_0535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VCSRO63_0537	COG0493	'glutamate synthase
VCSRO63_0538	COG0067	glutamate synthase
VCSRO63_0538	COG0069	glutamate synthase activity
VCSRO63_0538	COG0070	glutamate synthase
VCSRO63_0540	COG0070	glutamate synthase
VCSRO63_0540	COG0069	glutamate synthase activity
VCSRO63_0540	COG0067	glutamate synthase
VCSRO63_0541	COG1242	4 iron, 4 sulfur cluster binding
VCSRO63_0542	COG2203	Gaf domain
VCSRO63_0542	COG3706	GGDEF domain
VCSRO63_0542	COG4251	negative regulation of phosphorylation
VCSRO63_0542	COG5001	Diguanylate cyclase
VCSRO63_0543	COG0784	Response regulator, receiver
VCSRO63_0543	COG2198	Histidine kinase
VCSRO63_0543	COG5002	protein histidine kinase activity
VCSRO63_0544	COG0745	RESPONSE REGULATOR receiver
VCSRO63_0546	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCSRO63_0549	COG0083	homoserine kinase activity
VCSRO63_0550	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VCSRO63_0551	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VCSRO63_0552	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VCSRO63_0553	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VCSRO63_0556	COG1115	amino acid carrier protein
VCSRO63_0557	COG3022	response to hydroperoxide
VCSRO63_0559	COG0084	hydrolase, TatD family'
VCSRO63_0560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO63_0561	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VCSRO63_0562	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO63_0563	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VCSRO63_0564	COG0813	purine-nucleoside phosphorylase activity
VCSRO63_0566	COG0560	Phosphoserine phosphatase
VCSRO63_0568	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VCSRO63_0569	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCSRO63_0570	COG1022	Amp-dependent synthetase and ligase
VCSRO63_0573	COG3250	beta-galactosidase activity
VCSRO63_0574	COG1609	Transcriptional regulator
VCSRO63_0575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO63_0578	COG0189	ligase activity
VCSRO63_0578	COG0569	domain protein
VCSRO63_0580	COG0456	acetyltransferase
VCSRO63_0582	COG2171	N-acyltransferase activity
VCSRO63_0583	COG3141	response to X-ray
VCSRO63_0586	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VCSRO63_0587	COG1074	ATP-dependent DNA helicase activity
VCSRO63_0588	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VCSRO63_0590	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCSRO63_0590	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VCSRO63_0592	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VCSRO63_0593	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VCSRO63_0594	COG2166	iron-sulfur cluster assembly
VCSRO63_0595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCSRO63_0596	COG0693	protein deglycase activity
VCSRO63_0597	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VCSRO63_0598	COG3248	Nucleoside-binding outer membrane protein
VCSRO63_0600	COG1595	DNA-templated transcription, initiation
VCSRO63_0602	COG2211	Major facilitator Superfamily
VCSRO63_0605	COG2813	Specifically methylates the guanine in position
VCSRO63_0606	COG0271	Belongs to the BolA IbaG family
VCSRO63_0607	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO63_0608	COG1805	sodium ion transport
VCSRO63_0609	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO63_0610	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO63_0611	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO63_0612	COG2871	sodium ion transport
VCSRO63_0613	COG1477	protein flavinylation
VCSRO63_0617	COG3706	GGDEF domain
VCSRO63_0618	COG0733	neurotransmitter:sodium symporter activity
VCSRO63_0620	COG0189	ligase activity
VCSRO63_0621	COG0189	ligase activity
VCSRO63_0621	COG4067	protein conserved in archaea
VCSRO63_0622	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO63_0623	COG2252	PERMEase
VCSRO63_0624	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VCSRO63_0625	COG1073	alpha beta
VCSRO63_0627	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VCSRO63_0628	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VCSRO63_0629	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VCSRO63_0630	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO63_0630	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO63_0633	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VCSRO63_0634	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCSRO63_0635	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VCSRO63_0636	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VCSRO63_0638	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VCSRO63_0639	COG0024	Methionine aminopeptidase
VCSRO63_0640	COG0052	Belongs to the universal ribosomal protein uS2 family
VCSRO63_0641	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VCSRO63_0642	COG0528	UMP kinase activity
VCSRO63_0643	COG0233	cytoplasmic translational termination
VCSRO63_0644	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VCSRO63_0645	COG0575	Belongs to the CDS family
VCSRO63_0646	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VCSRO63_0647	COG0750	zinc metalloprotease
VCSRO63_0649	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VCSRO63_0650	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO63_0651	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCSRO63_0652	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO63_0653	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO63_0654	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
VCSRO63_0655	COG0587	DNA-directed DNA polymerase activity
VCSRO63_0656	COG0825	malonyl-CoA metabolic process
VCSRO63_0657	COG0037	tRNA processing
VCSRO63_0659	COG3479	Phenolic acid decarboxylase
VCSRO63_0660	COG0347	Belongs to the P(II) protein family
VCSRO63_0661	COG3021	interspecies interaction between organisms
VCSRO63_0662	COG0741	lytic transglycosylase activity
VCSRO63_0662	COG1388	LysM domain
VCSRO63_0663	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCSRO63_0664	COG2226	methyltransferase
VCSRO63_0665	COG0328	RNA-DNA hybrid ribonuclease activity
VCSRO63_0668	COG1960	acyl-CoA dehydrogenase activity
VCSRO63_0669	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCSRO63_0670	COG0121	glutamine amidotransferase
VCSRO63_0671	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VCSRO63_0672	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VCSRO63_0673	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VCSRO63_0675	COG1187	pseudouridine synthase activity
VCSRO63_0676	COG2840	Smr protein MutS2
VCSRO63_0682	COG2217	Heavy metal translocating P-type atpase
VCSRO63_0682	COG2608	mercury ion transmembrane transporter activity
VCSRO63_0683	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCSRO63_0686	COG1629	transport
VCSRO63_0686	COG4774	siderophore transport
VCSRO63_0687	COG2375	cellular response to nickel ion
VCSRO63_0688	COG2226	methyltransferase
VCSRO63_0688	COG3433	isochorismatase activity
VCSRO63_0688	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCSRO63_0695	COG0784	Response regulator, receiver
VCSRO63_0695	COG0835	chemotaxis
VCSRO63_0696	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCSRO63_0697	COG1815	bacterial-type flagellum-dependent cell motility
VCSRO63_0700	COG1749	Flagellar hook protein flgE
VCSRO63_0701	COG4787	bacterial-type flagellum-dependent cell motility
VCSRO63_0703	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VCSRO63_0704	COG1706	bacterial-type flagellum-dependent cell motility
VCSRO63_0705	COG3951	Flagellar rod assembly protein muramidase FlgJ
VCSRO63_0705	COG1705	Flagellar rod assembly protein muramidase FlgJ
VCSRO63_0708	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO63_0709	COG4974	Belongs to the 'phage' integrase family
VCSRO63_0730	COG4695	Portal protein
VCSRO63_0755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO63_0772	COG0012	GTP binding
VCSRO63_0773	COG0193	aminoacyl-tRNA hydrolase activity
VCSRO63_0774	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VCSRO63_0775	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VCSRO63_0776	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VCSRO63_0777	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VCSRO63_0778	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VCSRO63_0779	COG2890	protein-(glutamine-N5) methyltransferase activity
VCSRO63_0781	COG2912	Transglutaminase-like superfamily
VCSRO63_0782	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VCSRO63_0783	COG0737	Belongs to the 5'-nucleotidase family
VCSRO63_0784	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VCSRO63_0785	COG2233	PERMEase
VCSRO63_0790	COG1393	Belongs to the ArsC family
VCSRO63_0791	COG4783	chaperone-mediated protein folding
VCSRO63_0795	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VCSRO63_0798	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VCSRO63_0800	COG1876	peptidase activity
VCSRO63_0802	COG1393	Belongs to the ArsC family
VCSRO63_0806	COG2837	iron assimilation
VCSRO63_0807	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO63_0808	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO63_0809	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO63_0810	COG1334	flagellar protein FlaG
VCSRO63_0811	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VCSRO63_0813	COG1516	flagellar protein fliS
VCSRO63_0817	COG1677	Flagellar hook-basal body complex protein FliE
VCSRO63_0819	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VCSRO63_0820	COG1317	bacterial-type flagellum organization
VCSRO63_0824	COG1580	Controls the rotational direction of flagella during chemotaxis
VCSRO63_0829	COG1987	bacterial-type flagellum assembly
VCSRO63_0830	COG1684	flagellar biosynthetic protein fliR
VCSRO63_0832	COG2840	Smr protein MutS2
VCSRO63_0833	COG2890	protein-(glutamine-N5) methyltransferase activity
VCSRO63_0834	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VCSRO63_0835	COG2860	membrane
VCSRO63_0836	COG3101	peptidyl-lysine hydroxylation
VCSRO63_0838	COG0431	NADPH-dependent FMN reductase
VCSRO63_0839	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VCSRO63_0839	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VCSRO63_0840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCSRO63_0841	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO63_0842	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCSRO63_0843	COG0735	belongs to the Fur family
VCSRO63_0845	COG0583	DNA-binding transcription factor activity
VCSRO63_0847	COG1346	cytolysis
VCSRO63_0850	COG0596	Alpha beta hydrolase
VCSRO63_0851	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VCSRO63_0852	COG0033	Phosphoglucomutase
VCSRO63_0854	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VCSRO63_0855	COG0372	Belongs to the citrate synthase family
VCSRO63_0856	COG2009	succinate dehydrogenase
VCSRO63_0857	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VCSRO63_0858	COG1053	succinate dehydrogenase
VCSRO63_0860	COG0567	Dehydrogenase, E1 component
VCSRO63_0861	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCSRO63_0862	COG0045	succinate-CoA ligase (ADP-forming) activity
VCSRO63_0864	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VCSRO63_0865	COG1121	(ABC) transporter
VCSRO63_0866	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VCSRO63_0867	COG4977	sequence-specific DNA binding
VCSRO63_0868	COG1918	ferrous iron import across plasma membrane
VCSRO63_0872	COG0018	arginyl-trna synthetase
VCSRO63_0874	COG1025	Belongs to the peptidase M16 family
VCSRO63_0875	COG2062	phosphohistidine phosphatase, SixA
VCSRO63_0881	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VCSRO63_0882	COG0643	Histidine kinase
VCSRO63_0882	COG2198	Histidine kinase
VCSRO63_0882	COG0784	Response regulator, receiver
VCSRO63_0883	COG2201	protein-glutamate methylesterase activity
VCSRO63_0884	COG1192	Involved in chromosome partitioning
VCSRO63_0886	COG0835	chemotaxis
VCSRO63_0888	COG4133	protoheme IX ABC transporter activity
VCSRO63_0889	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCSRO63_0890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCSRO63_0892	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VCSRO63_0893	COG1138	Cytochrome C-type biogenesis protein
VCSRO63_0894	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VCSRO63_0895	COG4235	cytochrome complex assembly
VCSRO63_0895	COG3088	subunit of a heme lyase
VCSRO63_0897	COG2853	Lipoprotein
VCSRO63_0901	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VCSRO63_0902	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCSRO63_0903	COG0123	including yeast histone deacetylase and acetoin utilization protein
VCSRO63_0906	COG3083	sulfuric ester hydrolase activity
VCSRO63_0907	COG3082	Protein of unknown function (DUF1414)
VCSRO63_0908	COG3081	Nucleoid-associated protein
VCSRO63_0910	COG1757	Na H antiporter
VCSRO63_0911	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCSRO63_0912	COG2095	MarC family integral membrane protein
VCSRO63_0913	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO63_0913	COG1454	alcohol dehydrogenase
VCSRO63_0915	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO63_0916	COG1530	ribonuclease E activity
VCSRO63_0917	COG0564	pseudouridine synthase activity
VCSRO63_0918	COG0424	maF-like protein
VCSRO63_0919	COG1399	metal-binding, possibly nucleic acid-binding protein
VCSRO63_0920	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VCSRO63_0921	COG0416	fatty acid biosynthetic process
VCSRO63_0922	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCSRO63_0924	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO63_0925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VCSRO63_0926	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCSRO63_0927	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCSRO63_0928	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VCSRO63_0929	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VCSRO63_0931	COG0084	hydrolase, TatD family'
VCSRO63_0932	COG1263	PTS System
VCSRO63_0932	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO63_0934	COG0733	neurotransmitter:sodium symporter activity
VCSRO63_0937	COG4667	esterase of the alpha-beta hydrolase superfamily
VCSRO63_0939	COG1940	carbohydrate kinase activity
VCSRO63_0940	COG0835	chemotaxis
VCSRO63_0940	COG0784	Response regulator, receiver
VCSRO63_0943	COG2226	methyltransferase
VCSRO63_0945	COG0676	glucose-6-phosphate 1-epimerase activity
VCSRO63_0946	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO63_0947	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO63_0949	COG3139	Protein of unknown function (DUF1315)
VCSRO63_0950	COG0252	asparaginase activity
VCSRO63_0951	COG0616	signal peptide processing
VCSRO63_0952	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCSRO63_0952	COG1902	pentaerythritol trinitrate reductase activity
VCSRO63_0953	COG0788	formyltetrahydrofolate deformylase activity
VCSRO63_0955	COG1199	ATP-dependent helicase activity
VCSRO63_0956	COG1214	PFAM Peptidase M22, glycoprotease
VCSRO63_0959	COG0596	Alpha beta hydrolase
VCSRO63_0960	COG0318	PFAM AMP-dependent synthetase and ligase
VCSRO63_0961	COG0318	PFAM AMP-dependent synthetase and ligase
VCSRO63_0962	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VCSRO63_0966	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VCSRO63_0967	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VCSRO63_0968	COG0436	Aminotransferase
VCSRO63_0969	COG1169	isochorismate synthase
VCSRO63_0970	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VCSRO63_0971	COG0596	Alpha beta hydrolase
VCSRO63_0975	COG3135	benzoate transporter
VCSRO63_0976	COG1396	sequence-specific DNA binding
VCSRO63_0977	COG0840	transmembrane signaling receptor activity
VCSRO63_0983	COG3015	lipoprotein NlpE involved in copper resistance
VCSRO63_0984	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VCSRO63_0985	COG2894	cell division
VCSRO63_0986	COG0850	regulation of cytokinetic process
VCSRO63_0987	COG3100	YcgL domain-containing protein
VCSRO63_0988	COG2951	lytic endotransglycosylase activity
VCSRO63_0990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO63_0991	COG3469	chitinase activity
VCSRO63_0991	COG3325	Belongs to the glycosyl hydrolase 18 family
VCSRO63_0992	COG3005	denitrification pathway
VCSRO63_0993	COG0243	molybdopterin cofactor binding
VCSRO63_0997	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO63_0999	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VCSRO63_1006	COG4589	Belongs to the CDS family
VCSRO63_1008	COG5001	Diguanylate cyclase
VCSRO63_1008	COG3300	MHYT domain
VCSRO63_1011	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VCSRO63_1012	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCSRO63_1013	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCSRO63_1014	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCSRO63_1016	COG4191	Histidine kinase
VCSRO63_1017	COG0544	peptidyl-prolyl cis-trans isomerase activity
VCSRO63_1019	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VCSRO63_1020	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VCSRO63_1021	COG0776	regulation of translation
VCSRO63_1022	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO63_1023	COG1555	photosystem II stabilization
VCSRO63_1024	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VCSRO63_1025	COG0539	negative regulation of cytoplasmic translation
VCSRO63_1026	COG0776	regulation of translation
VCSRO63_1027	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VCSRO63_1028	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VCSRO63_1032	COG0583	DNA-binding transcription factor activity
VCSRO63_1034	COG0686	Belongs to the AlaDH PNT family
VCSRO63_1036	COG1674	ftsk spoiiie
VCSRO63_1037	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VCSRO63_1038	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCSRO63_1039	COG2186	Transcriptional regulator
VCSRO63_1042	COG0537	adenosine 5'-monophosphoramidase activity
VCSRO63_1047	COG3150	esterase
VCSRO63_1048	COG1252	NADH dehydrogenase
VCSRO63_1052	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VCSRO63_1054	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO63_1055	COG1136	(ABC) transporter
VCSRO63_1056	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO63_1058	COG0658	competence protein
VCSRO63_1058	COG2333	competence protein COMEC
VCSRO63_1059	COG1132	(ABC) transporter
VCSRO63_1060	COG1663	tetraacyldisaccharide 4'-kinase activity
VCSRO63_1061	COG2835	tetraacyldisaccharide 4'-kinase activity
VCSRO63_1062	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VCSRO63_1063	COG2719	SpoVR family
VCSRO63_1064	COG2718	Belongs to the UPF0229 family
VCSRO63_1065	COG2766	serine protein kinase
VCSRO63_1066	COG2766	serine protein kinase
VCSRO63_1067	COG3013	Belongs to the UPF0304 family
VCSRO63_1069	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VCSRO63_1070	COG0840	transmembrane signaling receptor activity
VCSRO63_1072	COG1882	Formate acetyltransferase
VCSRO63_1079	COG4160	amino acid transport
VCSRO63_1080	COG0708	Exodeoxyribonuclease III
VCSRO63_1081	COG0840	transmembrane signaling receptor activity
VCSRO63_1083	COG3923	Primosomal replication protein n
VCSRO63_1084	COG0730	response to heat
VCSRO63_1085	COG1199	ATP-dependent helicase activity
VCSRO63_1086	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCSRO63_1088	COG3012	SEC-C Motif Domain Protein
VCSRO63_1089	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCSRO63_1090	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO63_1091	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCSRO63_1092	COG0215	cysteine-tRNA ligase activity
VCSRO63_1093	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VCSRO63_1094	COG0632	four-way junction helicase activity
VCSRO63_1097	COG1271	oxidase subunit
VCSRO63_1098	COG1294	oxidase, subunit
VCSRO63_1099	COG4890	Cyd operon protein YbgT
VCSRO63_1100	COG0824	Thioesterase
VCSRO63_1101	COG0811	peptide transport
VCSRO63_1104	COG0823	Involved in the tonB-independent uptake of proteins
VCSRO63_1105	COG2885	chlorophyll binding
VCSRO63_1107	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VCSRO63_1109	COG0784	Response regulator, receiver
VCSRO63_1109	COG5002	protein histidine kinase activity
VCSRO63_1111	COG1482	cell wall glycoprotein biosynthetic process
VCSRO63_1112	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO63_1112	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO63_1112	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO63_1113	COG2207	Transcriptional regulator
VCSRO63_1115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO63_1116	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO63_1117	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO63_1119	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO63_1120	COG3284	Transcriptional regulator
VCSRO63_1121	COG4628	conserved protein (DUF2132)
VCSRO63_1123	COG0415	Belongs to the DNA photolyase family
VCSRO63_1129	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO63_1131	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCSRO63_1131	COG3008	intermembrane lipid transfer
VCSRO63_1132	COG2995	paraquat-inducible protein a
VCSRO63_1133	COG1309	transcriptional regulator
VCSRO63_1134	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO63_1139	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCSRO63_1140	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VCSRO63_1142	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VCSRO63_1145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCSRO63_1146	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCSRO63_1147	COG0297	glycogen (starch) synthase activity
VCSRO63_1151	COG3070	regulator of competence-specific genes
VCSRO63_1152	COG1609	Transcriptional regulator
VCSRO63_1154	COG0745	RESPONSE REGULATOR receiver
VCSRO63_1155	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCSRO63_1156	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCSRO63_1157	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VCSRO63_1158	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VCSRO63_1160	COG1979	alcohol dehydrogenase
VCSRO63_1161	COG2207	Transcriptional regulator
VCSRO63_1165	COG1032	radical SAM domain protein
VCSRO63_1166	COG5001	Diguanylate cyclase
VCSRO63_1167	COG0612	Peptidase, M16
VCSRO63_1170	COG0583	DNA-binding transcription factor activity
VCSRO63_1171	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VCSRO63_1173	COG2350	Protein conserved in bacteria
VCSRO63_1174	COG1607	acyl-coa hydrolase
VCSRO63_1177	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCSRO63_1178	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCSRO63_1180	COG2116	formate transmembrane transporter activity
VCSRO63_1181	COG4459	periplasmic nitrate reductase
VCSRO63_1182	COG3005	denitrification pathway
VCSRO63_1183	COG0243	molybdopterin cofactor binding
VCSRO63_1187	COG1227	inorganic diphosphatase activity
VCSRO63_1190	COG4172	Belongs to the ABC transporter superfamily
VCSRO63_1193	COG4168	peptide transport system, permease
VCSRO63_1195	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VCSRO63_1196	COG1842	Phage shock protein A
VCSRO63_1199	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO63_1202	COG2818	Glycosylase
VCSRO63_1203	COG0626	cystathionine gamma-synthase activity
VCSRO63_1205	COG0733	neurotransmitter:sodium symporter activity
VCSRO63_1209	COG0564	pseudouridine synthase activity
VCSRO63_1210	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VCSRO63_1211	COG4136	ATPase activity
VCSRO63_1212	COG4135	transport system, permease component
VCSRO63_1213	COG4134	Bacterial extracellular solute-binding protein
VCSRO63_1215	COG3313	Fe-S protein
VCSRO63_1217	COG0842	Transport permease protein
VCSRO63_1218	COG1131	(ABC) transporter
VCSRO63_1219	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO63_1220	COG0814	amino acid
VCSRO63_1223	COG2239	Acts as a magnesium transporter
VCSRO63_1224	COG0784	Response regulator, receiver
VCSRO63_1224	COG2205	protein histidine kinase activity
VCSRO63_1227	COG4934	collagen metabolic process
VCSRO63_1233	COG0840	transmembrane signaling receptor activity
VCSRO63_1235	COG5001	Diguanylate cyclase
VCSRO63_1235	COG4251	negative regulation of phosphorylation
VCSRO63_1235	COG3706	GGDEF domain
VCSRO63_1235	COG2203	Gaf domain
VCSRO63_1236	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VCSRO63_1240	COG1061	Type III restriction enzyme res subunit
VCSRO63_1241	COG1187	pseudouridine synthase activity
VCSRO63_1242	COG2814	Major facilitator Superfamily
VCSRO63_1244	COG0702	epimerase
VCSRO63_1245	COG0534	Mate efflux family protein
VCSRO63_1246	COG4181	ATPase activity
VCSRO63_1247	COG0577	efflux transmembrane transporter activity
VCSRO63_1249	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCSRO63_1251	COG1748	Saccharopine dehydrogenase
VCSRO63_1254	COG1538	Outer membrane efflux protein
VCSRO63_1256	COG3385	transposase activity
VCSRO63_1259	COG0583	DNA-binding transcription factor activity
VCSRO63_1261	COG1451	nucleotide metabolic process
VCSRO63_1264	COG3063	Type IV pilus biogenesis stability protein PilW
VCSRO63_1265	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VCSRO63_1269	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO63_1272	COG3290	protein histidine kinase activity
VCSRO63_1273	COG4565	transcriptional regulatory protein
VCSRO63_1275	COG0835	chemotaxis
VCSRO63_1275	COG0784	Response regulator, receiver
VCSRO63_1283	COG1085	galactose-1-phosphate uridylyltransferase
VCSRO63_1284	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VCSRO63_1285	COG2017	converts alpha-aldose to the beta-anomer
VCSRO63_1287	COG2200	EAL domain
VCSRO63_1291	COG3527	Alpha-acetolactate decarboxylase
VCSRO63_1294	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCSRO63_1296	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCSRO63_1299	COG3097	Belongs to the UPF0267 family
VCSRO63_1304	COG1271	oxidase subunit
VCSRO63_1305	COG1294	oxidase, subunit
VCSRO63_1306	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO63_1306	COG1136	(ABC) transporter
VCSRO63_1307	COG0577	efflux transmembrane transporter activity
VCSRO63_1307	COG1136	(ABC) transporter
VCSRO63_1308	COG1136	(ABC) transporter
VCSRO63_1308	COG0577	efflux transmembrane transporter activity
VCSRO63_1312	COG0583	DNA-binding transcription factor activity
VCSRO63_1314	COG2723	6-phospho-beta-galactosidase activity
VCSRO63_1315	COG0848	biopolymer transport protein
VCSRO63_1316	COG3001	Fructosamine kinase
VCSRO63_1318	COG0791	NLP P60 protein
VCSRO63_1319	COG0840	transmembrane signaling receptor activity
VCSRO63_1319	COG3290	protein histidine kinase activity
VCSRO63_1321	COG3148	PFAM DTW domain containing protein
VCSRO63_1322	COG1940	carbohydrate kinase activity
VCSRO63_1324	COG0303	'Molybdopterin
VCSRO63_1325	COG0746	molybdenum cofactor guanylyltransferase activity
VCSRO63_1326	COG3842	ATPase activity
VCSRO63_1327	COG4662	Binding-protein-dependent transport system inner membrane component
VCSRO63_1329	COG2204	response regulator
VCSRO63_1330	COG3852	Histidine kinase
VCSRO63_1331	COG0488	(ABC) transporter
VCSRO63_1332	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VCSRO63_1338	COG0243	molybdopterin cofactor binding
VCSRO63_1338	COG3383	formate dehydrogenase (NAD+) activity
VCSRO63_1339	COG0437	4 iron, 4 sulfur cluster binding
VCSRO63_1342	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VCSRO63_1343	COG1666	GTP binding
VCSRO63_1344	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO63_1347	COG2996	Protein conserved in bacteria
VCSRO63_1349	COG3008	intermembrane lipid transfer
VCSRO63_1350	COG2995	paraquat-inducible protein a
VCSRO63_1351	COG1132	(ABC) transporter
VCSRO63_1352	COG1956	GAF domain-containing protein
VCSRO63_1353	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VCSRO63_1356	COG0308	aminopeptidase N
VCSRO63_1358	COG0167	dihydroorotate dehydrogenase activity
VCSRO63_1360	COG0116	Belongs to the methyltransferase superfamily
VCSRO63_1360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCSRO63_1362	COG0488	(ABC) transporter
VCSRO63_1365	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCSRO63_1366	COG1067	ATP-dependent peptidase activity
VCSRO63_1367	COG3120	sequence-specific DNA binding
VCSRO63_1370	COG3064	Membrane
VCSRO63_1370	COG1073	alpha beta
VCSRO63_1370	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VCSRO63_1371	COG2994	toxin metabolic process
VCSRO63_1376	COG0784	Response regulator, receiver
VCSRO63_1376	COG2205	protein histidine kinase activity
VCSRO63_1379	COG3278	Belongs to the heme-copper respiratory oxidase family
VCSRO63_1382	COG2010	Cytochrome c
VCSRO63_1384	COG2217	Heavy metal translocating P-type atpase
VCSRO63_1387	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VCSRO63_1388	COG0589	response to stress
VCSRO63_1389	COG0037	tRNA processing
VCSRO63_1393	COG3842	ATPase activity
VCSRO63_1395	COG1177	transmembrane transport
VCSRO63_1397	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCSRO63_1400	COG1115	amino acid carrier protein
VCSRO63_1401	COG1280	lysine exporter protein (LysE YggA)
VCSRO63_1406	COG3675	Pfam Lipase (class 3)
VCSRO63_1408	COG3501	Rhs element vgr protein
VCSRO63_1410	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VCSRO63_1411	COG0840	transmembrane signaling receptor activity
VCSRO63_1412	COG2814	Major facilitator Superfamily
VCSRO63_1413	COG1566	PFAM secretion protein HlyD family protein
VCSRO63_1414	COG1538	Outer membrane efflux protein
VCSRO63_1416	COG0513	Belongs to the DEAD box helicase family
VCSRO63_1418	COG0840	transmembrane signaling receptor activity
VCSRO63_1419	COG0840	transmembrane signaling receptor activity
VCSRO63_1420	COG0835	chemotaxis
VCSRO63_1421	COG2201	protein-glutamate methylesterase activity
VCSRO63_1423	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCSRO63_1424	COG0784	Response regulator, receiver
VCSRO63_1424	COG2198	Histidine kinase
VCSRO63_1424	COG0643	Histidine kinase
VCSRO63_1425	COG0643	Histidine kinase
VCSRO63_1425	COG2198	Histidine kinase
VCSRO63_1427	COG0745	RESPONSE REGULATOR receiver
VCSRO63_1430	COG0415	Belongs to the DNA photolyase family
VCSRO63_1431	COG0477	Major facilitator Superfamily
VCSRO63_1432	COG0583	DNA-binding transcription factor activity
VCSRO63_1433	COG0095	Lipoate-protein ligase
VCSRO63_1434	COG0443	Heat shock 70 kDa protein
VCSRO63_1436	COG1643	Atp-dependent helicase
VCSRO63_1437	COG1643	Atp-dependent helicase
VCSRO63_1445	COG0443	Heat shock 70 kDa protein
VCSRO63_1446	COG3706	GGDEF domain
VCSRO63_1452	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VCSRO63_1453	COG0602	queuosine metabolic process
VCSRO63_1454	COG0561	phosphatase activity
VCSRO63_1456	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO63_1457	COG4597	amino acid ABC transporter
VCSRO63_1458	COG0765	amino acid transport
VCSRO63_1459	COG1126	abc transporter atp-binding protein
VCSRO63_1460	COG0670	Belongs to the BI1 family
VCSRO63_1461	COG2920	part of a sulfur-relay system
VCSRO63_1462	COG1254	Belongs to the acylphosphatase family
VCSRO63_1463	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCSRO63_1464	COG3706	GGDEF domain
VCSRO63_1466	COG2205	protein histidine kinase activity
VCSRO63_1466	COG3437	response regulator, receiver
VCSRO63_1466	COG3850	Histidine kinase
VCSRO63_1466	COG4999	Histidine kinase
VCSRO63_1467	COG3437	response regulator, receiver
VCSRO63_1468	COG0625	glutathione transferase activity
VCSRO63_1470	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VCSRO63_1472	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO63_1479	COG0372	Belongs to the citrate synthase family
VCSRO63_1480	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VCSRO63_1485	COG0583	DNA-binding transcription factor activity
VCSRO63_1486	COG4771	TonB-dependent receptor
VCSRO63_1491	COG1129	ABC transporter
VCSRO63_1496	COG0745	RESPONSE REGULATOR receiver
VCSRO63_1497	COG2205	protein histidine kinase activity
VCSRO63_1498	COG3713	MltA-interacting MipA family protein
VCSRO63_1499	COG2990	Protein conserved in bacteria
VCSRO63_1501	COG4191	Histidine kinase
VCSRO63_1501	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO63_1502	COG0471	metal ion transport
VCSRO63_1504	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCSRO63_1507	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO63_1509	COG3768	UPF0283 membrane protein
VCSRO63_1510	COG3106	COG3106 Predicted ATPase
VCSRO63_1513	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCSRO63_1514	COG0494	nUDIX hydrolase
VCSRO63_1515	COG0814	amino acid
VCSRO63_1516	COG1760	l-serine dehydratase
VCSRO63_1517	COG0720	synthase
VCSRO63_1519	COG0017	Asparaginyl-tRNA synthetase
VCSRO63_1520	COG0351	phosphomethylpyrimidine kinase
VCSRO63_1521	COG3437	response regulator, receiver
VCSRO63_1521	COG2770	Histidine kinase
VCSRO63_1522	COG1448	Aminotransferase
VCSRO63_1525	COG0840	transmembrane signaling receptor activity
VCSRO63_1526	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
VCSRO63_1527	COG2943	transferase activity, transferring hexosyl groups
VCSRO63_1528	COG1609	Transcriptional regulator
VCSRO63_1530	COG1486	melibiose metabolic process
VCSRO63_1531	COG1447	Phosphotransferase system cellobiose-specific component IIA
VCSRO63_1533	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VCSRO63_1534	COG0726	polysaccharide deacetylase
VCSRO63_1535	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VCSRO63_1536	COG1846	Transcriptional regulator
VCSRO63_1541	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCSRO63_1544	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCSRO63_1545	COG3108	Peptidase M15
VCSRO63_1551	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VCSRO63_1553	COG2814	Major facilitator Superfamily
VCSRO63_1555	COG1054	Belongs to the UPF0176 family
VCSRO63_1557	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCSRO63_1558	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCSRO63_1559	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCSRO63_1568	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
VCSRO63_1569	COG4139	cobalamin transport
VCSRO63_1570	COG2988	succinylglutamate desuccinylase activity
VCSRO63_1573	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VCSRO63_1574	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VCSRO63_1575	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO63_1576	COG1823	symporter activity
VCSRO63_1577	COG2925	Exonuclease
VCSRO63_1578	COG1380	Effector of murein hydrolase LrgA
VCSRO63_1579	COG1346	cytolysis
VCSRO63_1586	COG0776	regulation of translation
VCSRO63_1587	COG0072	phenylalanine-tRNA ligase activity
VCSRO63_1587	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO63_1588	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VCSRO63_1596	COG0322	excinuclease ABC activity
VCSRO63_1597	COG2197	response regulator
VCSRO63_1598	COG0417	DNA replication proofreading
VCSRO63_1599	COG5001	Diguanylate cyclase
VCSRO63_1601	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCSRO63_1602	COG3099	Belongs to the UPF0263 family
VCSRO63_1605	COG1228	amidohydrolase
VCSRO63_1606	COG0010	Belongs to the arginase family
VCSRO63_1607	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VCSRO63_1608	COG2986	histidine ammonia-lyase
VCSRO63_1613	COG0247	lactate metabolic process
VCSRO63_1613	COG0277	FAD linked oxidase domain protein
VCSRO63_1616	COG2885	chlorophyll binding
VCSRO63_1620	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VCSRO63_1622	COG0281	malic enzyme
VCSRO63_1624	COG2949	membrane
VCSRO63_1625	COG3706	GGDEF domain
VCSRO63_1626	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCSRO63_1628	COG0492	ferredoxin-NADP+ reductase activity
VCSRO63_1629	COG4988	ABC transporter
VCSRO63_1630	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VCSRO63_1631	COG1187	pseudouridine synthase activity
VCSRO63_1632	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO63_1633	COG0613	PHP domain protein
VCSRO63_1634	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCSRO63_1635	COG0512	Glutamine amidotransferase of anthranilate synthase
VCSRO63_1636	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VCSRO63_1637	COG0134	indole-3-glycerol-phosphate synthase activity
VCSRO63_1637	COG0135	phosphoribosylanthranilate isomerase activity
VCSRO63_1638	COG0133	tryptophan synthase activity
VCSRO63_1639	COG0159	tryptophan synthase activity
VCSRO63_1641	COG1435	thymidine kinase activity
VCSRO63_1642	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VCSRO63_1643	COG1801	Protein of unknown function DUF72
VCSRO63_1644	COG4106	trans-aconitate 2-methyltransferase activity
VCSRO63_1645	COG0500	methyltransferase
VCSRO63_1646	COG4067	protein conserved in archaea
VCSRO63_1646	COG0189	ligase activity
VCSRO63_1649	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VCSRO63_1651	COG3852	Histidine kinase
VCSRO63_1654	COG3070	regulator of competence-specific genes
VCSRO63_1656	COG2431	L-lysine efflux transmembrane transporter activity
VCSRO63_1658	COG0076	glutamate decarboxylase activity
VCSRO63_1659	COG1737	Transcriptional regulator
VCSRO63_1660	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO63_1660	COG1454	alcohol dehydrogenase
VCSRO63_1661	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCSRO63_1662	COG3273	potassium ion transport
VCSRO63_1662	COG2985	domain, Protein
VCSRO63_1663	COG0542	response to heat
VCSRO63_1664	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VCSRO63_1665	COG1278	Cold shock
VCSRO63_1667	COG1187	pseudouridine synthase activity
VCSRO63_1668	COG0140	phosphoribosyl-ATP diphosphatase activity
VCSRO63_1668	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VCSRO63_1669	COG0107	imidazoleglycerol-phosphate synthase activity
VCSRO63_1670	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VCSRO63_1671	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VCSRO63_1672	COG0131	Imidazoleglycerol-phosphate dehydratase
VCSRO63_1672	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCSRO63_1673	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VCSRO63_1674	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VCSRO63_1675	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VCSRO63_1676	COG1757	Na H antiporter
VCSRO63_1677	COG2916	Histone family protein nucleoid-structuring protein H-NS
VCSRO63_1678	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO63_1679	COG0482	sulfurtransferase activity
VCSRO63_1680	COG2915	High frequency lysogenization protein hflD homolog
VCSRO63_1681	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VCSRO63_1683	COG2268	Band 7 protein
VCSRO63_1685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VCSRO63_1688	COG0300	oxidoreductase activity
VCSRO63_1690	COG0501	Belongs to the peptidase M48B family
VCSRO63_1692	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VCSRO63_1693	COG2226	methyltransferase
VCSRO63_1694	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO63_1695	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCSRO63_1696	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VCSRO63_1697	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VCSRO63_1698	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VCSRO63_1699	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VCSRO63_1700	COG0653	protein targeting
VCSRO63_1701	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO63_1702	COG2199	diguanylate cyclase activity
VCSRO63_1702	COG2203	Gaf domain
VCSRO63_1704	COG4120	Belongs to the binding-protein-dependent transport system permease family
VCSRO63_1706	COG4628	conserved protein (DUF2132)
VCSRO63_1707	COG3092	negative regulation of chromosome organization
VCSRO63_1708	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCSRO63_1709	COG0857	belongs to the CobB CobQ family
VCSRO63_1709	COG0280	phosphate acetyltransferase
VCSRO63_1710	COG0435	Glutathione S-transferase
VCSRO63_1711	COG4608	Belongs to the ABC transporter superfamily
VCSRO63_1712	COG0444	Belongs to the ABC transporter superfamily
VCSRO63_1713	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO63_1714	COG0601	transmembrane transport
VCSRO63_1718	COG2204	response regulator
VCSRO63_1719	COG3300	MHYT domain
VCSRO63_1719	COG5001	Diguanylate cyclase
VCSRO63_1720	COG4191	Histidine kinase
VCSRO63_1721	COG5002	protein histidine kinase activity
VCSRO63_1723	COG2201	protein-glutamate methylesterase activity
VCSRO63_1726	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO63_1729	COG1881	PFAM PEBP family protein
VCSRO63_1734	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO63_1735	COG0640	Transcriptional regulator
VCSRO63_1736	COG3706	GGDEF domain
VCSRO63_1740	COG1946	Acyl-CoA thioesterase
VCSRO63_1741	COG1522	sequence-specific DNA binding
VCSRO63_1743	COG0616	signal peptide processing
VCSRO63_1744	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO63_1745	COG2983	Belongs to the UPF0260 family
VCSRO63_1747	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VCSRO63_1748	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VCSRO63_1749	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
VCSRO63_1750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VCSRO63_1751	COG2832	Protein of unknown function (DUF454)
VCSRO63_1753	COG0745	RESPONSE REGULATOR receiver
VCSRO63_1754	COG0583	DNA-binding transcription factor activity
VCSRO63_1755	COG0778	Nitroreductase
VCSRO63_1756	COG1024	Enoyl-CoA hydratase
VCSRO63_1756	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCSRO63_1757	COG0183	Belongs to the thiolase family
VCSRO63_1760	COG2067	long-chain fatty acid transport protein
VCSRO63_1761	COG2067	long-chain fatty acid transport protein
VCSRO63_1763	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VCSRO63_1764	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VCSRO63_1765	COG2982	Protein involved in outer membrane biogenesis
VCSRO63_1766	COG0572	uridine kinase
VCSRO63_1767	COG0489	protein tyrosine kinase activity
VCSRO63_1768	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO63_1768	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO63_1770	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO63_1772	COG0517	IMP dehydrogenase activity
VCSRO63_1772	COG0617	tRNA 3'-terminal CCA addition
VCSRO63_1772	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
VCSRO63_1773	COG2199	diguanylate cyclase activity
VCSRO63_1774	COG0314	molybdopterin synthase activity
VCSRO63_1775	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VCSRO63_1776	COG0315	cyclic pyranopterin monophosphate synthase activity
VCSRO63_1777	COG0521	Mo-molybdopterin cofactor biosynthetic process
VCSRO63_1778	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VCSRO63_1779	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VCSRO63_1780	COG2198	Histidine kinase
VCSRO63_1781	COG2204	response regulator
VCSRO63_1782	COG0556	nucleotide-excision repair
VCSRO63_1784	COG4657	Part of a membrane complex involved in electron transport
VCSRO63_1785	COG2878	Part of a membrane complex involved in electron transport
VCSRO63_1786	COG4656	Part of a membrane complex involved in electron transport
VCSRO63_1789	COG4660	Part of a membrane complex involved in electron transport
VCSRO63_1790	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VCSRO63_1791	COG0346	lactoylglutathione lyase activity
VCSRO63_1794	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VCSRO63_1795	COG2056	Na+-H+ antiporter family
VCSRO63_1796	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VCSRO63_1797	COG1286	toxin biosynthetic process
VCSRO63_1798	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VCSRO63_1799	COG0285	dihydrofolate synthase activity
VCSRO63_1800	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VCSRO63_1801	COG0101	tRNA pseudouridine synthase activity
VCSRO63_1804	COG1263	PTS System
VCSRO63_1804	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO63_1804	COG2190	(PTS) system
VCSRO63_1805	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VCSRO63_1806	COG1940	carbohydrate kinase activity
VCSRO63_1806	COG1846	Transcriptional regulator
VCSRO63_1807	COG4651	solute:proton antiporter activity
VCSRO63_1807	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCSRO63_1808	COG0367	asparagine synthase
VCSRO63_1810	COG3104	oligopeptide transport
VCSRO63_1811	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VCSRO63_1812	COG0563	adenylate kinase activity
VCSRO63_1813	COG0326	Molecular chaperone. Has ATPase activity
VCSRO63_1814	COG3710	Transcriptional regulator
VCSRO63_1817	COG0622	Phosphoesterase
VCSRO63_1818	COG1090	epimerase
VCSRO63_1819	COG0300	oxidoreductase activity
VCSRO63_1820	COG3118	belongs to the thioredoxin family
VCSRO63_1821	COG0330	HflC and HflK could
VCSRO63_1822	COG1585	Membrane protein implicated in regulation of membrane protease activity
VCSRO63_1823	COG0789	Transcriptional regulator
VCSRO63_1826	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VCSRO63_1827	COG3115	cell septum assembly
VCSRO63_1828	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VCSRO63_1829	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VCSRO63_1830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO63_1832	COG2190	(PTS) system
VCSRO63_1833	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO63_1834	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCSRO63_1835	COG1702	phosphate starvation-inducible protein PhoH
VCSRO63_1836	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VCSRO63_1837	COG4535	Mg2 and Co2 transporter CorC
VCSRO63_1838	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VCSRO63_1839	COG2888	peptidyl-tyrosine sulfation
VCSRO63_1840	COG0495	leucyl-tRNA aminoacylation
VCSRO63_1841	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VCSRO63_1842	COG1466	dna polymerase III delta subunit
VCSRO63_1843	COG0799	negative regulation of ribosome biogenesis
VCSRO63_1844	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VCSRO63_1845	COG0768	penicillin binding
VCSRO63_1846	COG0772	Belongs to the SEDS family
VCSRO63_1847	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCSRO63_1848	COG1686	Belongs to the peptidase S11 family
VCSRO63_1849	COG2921	Belongs to the UPF0250 family
VCSRO63_1850	COG0321	lipoyl(octanoyl) transferase activity
VCSRO63_1851	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VCSRO63_1853	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCSRO63_1858	COG1596	polysaccharide export
VCSRO63_1860	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCSRO63_1866	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
VCSRO63_1868	COG0438	transferase activity, transferring glycosyl groups
VCSRO63_1870	COG1045	serine acetyltransferase
VCSRO63_1874	COG0110	maltose O-acetyltransferase activity
VCSRO63_1875	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VCSRO63_1876	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VCSRO63_1878	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO63_1884	COG0366	Alpha amylase catalytic
VCSRO63_1885	COG1263	PTS System
VCSRO63_1885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO63_1886	COG1609	Transcriptional regulator
VCSRO63_1887	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCSRO63_1888	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VCSRO63_1889	COG2011	ABC-type metal ion transport system permease component
VCSRO63_1890	COG1464	Belongs to the NlpA lipoprotein family
VCSRO63_1891	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VCSRO63_1893	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCSRO63_1893	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCSRO63_1896	COG1611	Belongs to the LOG family
VCSRO63_1897	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO63_1898	COG2363	Small membrane protein
VCSRO63_1899	COG0583	DNA-binding transcription factor activity
VCSRO63_1900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO63_1900	COG0301	tRNA thio-modification
VCSRO63_1902	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VCSRO63_1903	COG1722	exodeoxyribonuclease VII activity
VCSRO63_1904	COG0142	geranyltranstransferase activity
VCSRO63_1905	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VCSRO63_1906	COG0564	pseudouridine synthase activity
VCSRO63_1907	COG3098	single-species biofilm formation
VCSRO63_1910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO63_1912	COG1671	Belongs to the UPF0178 family
VCSRO63_1913	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCSRO63_1914	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCSRO63_1915	COG0254	rRNA binding
VCSRO63_1916	COG1720	tRNA m6t6A37 methyltransferase activity
VCSRO63_1917	COG0442	prolyl-tRNA aminoacylation
VCSRO63_1921	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VCSRO63_1921	COG0047	phosphoribosylformylglycinamidine synthase activity
VCSRO63_1922	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VCSRO63_1925	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCSRO63_1931	COG0484	heat shock protein binding
VCSRO63_1932	COG0443	Heat shock 70 kDa protein
VCSRO63_1933	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VCSRO63_1934	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VCSRO63_1935	COG0497	DNA recombination
VCSRO63_1936	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO63_1937	COG2914	Belongs to the UPF0125 (RnfH) family
VCSRO63_1938	COG2867	negative regulation of translational initiation
VCSRO63_1939	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VCSRO63_1949	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VCSRO63_1950	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VCSRO63_1951	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCSRO63_1955	COG3051	citrate lyase alpha subunit
VCSRO63_1956	COG2301	Belongs to the HpcH HpaI aldolase family
VCSRO63_1957	COG3052	prosthetic group binding
VCSRO63_1958	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
VCSRO63_1960	COG3630	sodium ion export across plasma membrane
VCSRO63_1961	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO63_1961	COG5016	pyruvate
VCSRO63_1962	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCSRO63_1964	COG4565	transcriptional regulatory protein
VCSRO63_1967	COG0583	DNA-binding transcription factor activity
VCSRO63_1969	COG1115	amino acid carrier protein
VCSRO63_1970	COG2015	COG2015, Alkyl sulfatase and related hydrolases
VCSRO63_1971	COG0583	DNA-binding transcription factor activity
VCSRO63_1973	COG1120	ATPase activity
VCSRO63_1974	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO63_1975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO63_1976	COG4592	Periplasmic binding protein
VCSRO63_1978	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO63_1979	COG1169	isochorismate synthase
VCSRO63_1980	COG1021	2,3-dihydroxybenzoate-AMP ligase
VCSRO63_1981	COG1535	isochorismatase
VCSRO63_1981	COG3433	isochorismatase activity
VCSRO63_1982	COG1584	GPR1 FUN34 yaaH family protein
VCSRO63_1984	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VCSRO63_1984	COG0519	Catalyzes the synthesis of GMP from XMP
VCSRO63_1985	COG0516	GMP reductase activity
VCSRO63_1985	COG0517	IMP dehydrogenase activity
VCSRO63_1986	COG1570	exodeoxyribonuclease VII activity
VCSRO63_1989	COG1160	GTP binding
VCSRO63_1990	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO63_1991	COG2976	Protein conserved in bacteria
VCSRO63_1992	COG0124	histidyl-tRNA synthetase
VCSRO63_1993	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VCSRO63_1994	COG1426	Protein conserved in bacteria
VCSRO63_1996	COG0105	UTP biosynthetic process
VCSRO63_1997	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCSRO63_1998	COG2975	iron-sulfur cluster assembly
VCSRO63_1999	COG0633	Ferredoxin
VCSRO63_2003	COG0822	iron-sulfur transferase activity
VCSRO63_2005	COG1959	2 iron, 2 sulfur cluster binding
VCSRO63_2007	COG0483	inositol monophosphate 1-phosphatase activity
VCSRO63_2008	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO63_2009	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO63_2010	COG1862	Preprotein translocase
VCSRO63_2012	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
VCSRO63_2013	COG0517	IMP dehydrogenase activity
VCSRO63_2015	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VCSRO63_2016	COG0583	DNA-binding transcription factor activity
VCSRO63_2017	COG0450	alkyl hydroperoxide reductase
VCSRO63_2018	COG3142	Participates in the control of copper homeostasis
VCSRO63_2021	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCSRO63_2022	COG0581	inorganic phosphate transmembrane transporter activity
VCSRO63_2024	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VCSRO63_2025	COG0248	Ppx GppA phosphatase
VCSRO63_2027	COG5002	protein histidine kinase activity
VCSRO63_2028	COG0745	RESPONSE REGULATOR receiver
VCSRO63_2030	COG0826	peptidase U32
VCSRO63_2031	COG0826	peptidase U32
VCSRO63_2032	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCSRO63_2040	COG0542	response to heat
VCSRO63_2042	COG0564	pseudouridine synthase activity
VCSRO63_2043	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO63_2044	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCSRO63_2045	COG0077	Prephenate dehydratase
VCSRO63_2045	COG1605	Chorismate mutase
VCSRO63_2046	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCSRO63_2047	COG5001	Diguanylate cyclase
VCSRO63_2049	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VCSRO63_2051	COG0488	(ABC) transporter
VCSRO63_2053	COG1605	Chorismate mutase
VCSRO63_2053	COG0287	Prephenate dehydrogenase
VCSRO63_2054	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO63_2055	COG3275	phosphorelay sensor kinase activity
VCSRO63_2056	COG3279	Response regulator of the LytR AlgR family
VCSRO63_2058	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VCSRO63_2059	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCSRO63_2062	COG1966	Carbon starvation protein
VCSRO63_2063	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VCSRO63_2064	COG1047	Peptidyl-prolyl cis-trans
VCSRO63_2065	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VCSRO63_2067	COG0196	riboflavin kinase activity
VCSRO63_2068	COG0728	peptidoglycan biosynthetic process
VCSRO63_2069	COG0268	Binds directly to 16S ribosomal RNA
VCSRO63_2070	COG0640	Transcriptional regulator
VCSRO63_2071	COG0583	DNA-binding transcription factor activity
VCSRO63_2072	COG1283	sodium-dependent phosphate transmembrane transporter activity
VCSRO63_2074	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VCSRO63_2075	COG0730	response to heat
VCSRO63_2076	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
VCSRO63_2077	COG0494	nUDIX hydrolase
VCSRO63_2079	COG0667	Aldo Keto reductase
VCSRO63_2081	COG2204	response regulator
VCSRO63_2082	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VCSRO63_2083	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VCSRO63_2086	COG0513	Belongs to the DEAD box helicase family
VCSRO63_2091	COG3153	acetyltransferase
VCSRO63_2092	COG3154	lipid carrier protein
VCSRO63_2094	COG0826	peptidase U32
VCSRO63_2095	COG0826	peptidase U32
VCSRO63_2099	COG1185	polyribonucleotide nucleotidyltransferase activity
VCSRO63_2100	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VCSRO63_2102	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VCSRO63_2103	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VCSRO63_2104	COG0195	Participates in both transcription termination and antitermination
VCSRO63_2105	COG0779	Required for maturation of 30S ribosomal subunits
VCSRO63_2108	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCSRO63_2111	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VCSRO63_2112	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VCSRO63_2113	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VCSRO63_2114	COG1534	Rna-binding protein
VCSRO63_2115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO63_2116	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCSRO63_2117	COG2027	D-alanyl-D-alanine carboxypeptidase
VCSRO63_2118	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCSRO63_2119	COG0739	heme binding
VCSRO63_2122	COG0316	Belongs to the HesB IscA family
VCSRO63_2123	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VCSRO63_2125	COG0628	permease
VCSRO63_2126	COG2813	Specifically methylates the guanine in position
VCSRO63_2127	COG0784	Response regulator, receiver
VCSRO63_2127	COG2205	protein histidine kinase activity
VCSRO63_2128	COG0747	negative chemotaxis
VCSRO63_2129	COG0601	transmembrane transport
VCSRO63_2130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO63_2131	COG0444	Belongs to the ABC transporter superfamily
VCSRO63_2132	COG4608	Belongs to the ABC transporter superfamily
VCSRO63_2134	COG2971	BadF BadG BcrA BcrD
VCSRO63_2138	COG3842	ATPase activity
VCSRO63_2140	COG1840	ABC-type Fe3 transport system, periplasmic component
VCSRO63_2141	COG0004	ammonium transporteR
VCSRO63_2142	COG0347	Belongs to the P(II) protein family
VCSRO63_2143	COG3112	Uncharacterised protein family (UPF0231)
VCSRO63_2144	COG1049	propionate catabolic process, 2-methylcitrate cycle
VCSRO63_2145	COG1752	Esterase of the alpha-beta hydrolase superfamily
VCSRO63_2146	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VCSRO63_2147	COG1643	Atp-dependent helicase
VCSRO63_2149	COG1489	DNA binding
VCSRO63_2151	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCSRO63_2153	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCSRO63_2154	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VCSRO63_2155	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VCSRO63_2156	COG0842	Transport permease protein
VCSRO63_2157	COG1131	(ABC) transporter
VCSRO63_2158	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO63_2159	COG0288	reversible hydration of carbon dioxide
VCSRO63_2162	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VCSRO63_2163	COG3107	peptidoglycan biosynthetic process
VCSRO63_2164	COG0792	nuclease activity
VCSRO63_2165	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCSRO63_2166	COG2823	Periplasmic or secreted lipoprotein
VCSRO63_2167	COG2969	positive regulation of protein catabolic process
VCSRO63_2168	COG0625	glutathione transferase activity
VCSRO63_2169	COG2857	Cytochrome c1
VCSRO63_2170	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VCSRO63_2171	COG0723	plastoquinol--plastocyanin reductase activity
VCSRO63_2172	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VCSRO63_2173	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VCSRO63_2174	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VCSRO63_2176	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCSRO63_2177	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCSRO63_2178	COG0335	large ribosomal subunit rRNA binding
VCSRO63_2179	COG0336	Belongs to the RNA methyltransferase TrmD family
VCSRO63_2180	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VCSRO63_2181	COG0228	four-way junction DNA binding
VCSRO63_2182	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VCSRO63_2184	COG4137	Cytochrome C assembly protein
VCSRO63_2185	COG4536	flavin adenine dinucleotide binding
VCSRO63_2186	COG1854	S-ribosylhomocysteine lyase activity
VCSRO63_2187	COG2918	glutathione biosynthetic process
VCSRO63_2188	COG0612	Peptidase, M16
VCSRO63_2189	COG1238	metal cluster binding
VCSRO63_2191	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCSRO63_2192	COG5016	pyruvate
VCSRO63_2192	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO63_2193	COG3630	sodium ion export across plasma membrane
VCSRO63_2202	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
VCSRO63_2203	COG0527	aspartate kinase activity
VCSRO63_2204	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VCSRO63_2205	COG2137	regulation of response to DNA damage stimulus
VCSRO63_2206	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VCSRO63_2208	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
VCSRO63_2209	COG4208	sulfate ABC transporter
VCSRO63_2213	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VCSRO63_2214	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCSRO63_2216	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VCSRO63_2217	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VCSRO63_2218	COG0585	pseudouridine synthase activity
VCSRO63_2219	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VCSRO63_2220	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VCSRO63_2221	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VCSRO63_2222	COG1968	undecaprenyl-diphosphatase activity
VCSRO63_2223	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCSRO63_2224	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VCSRO63_2225	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VCSRO63_2227	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VCSRO63_2228	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VCSRO63_2229	COG1610	YqeY-like protein
VCSRO63_2230	COG0358	DNA primase activity
VCSRO63_2248	COG2378	regulation of single-species biofilm formation
VCSRO63_2251	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCSRO63_2252	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VCSRO63_2253	COG1349	DNA-binding transcription factor activity
VCSRO63_2258	COG1279	arginine transmembrane transporter activity
VCSRO63_2259	COG0668	transmembrane transport
VCSRO63_2260	COG0191	fructose-bisphosphate aldolase activity
VCSRO63_2261	COG0126	phosphoglycerate kinase activity
VCSRO63_2262	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO63_2263	COG4771	TonB-dependent receptor
VCSRO63_2264	COG0583	DNA-binding transcription factor activity
VCSRO63_2265	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCSRO63_2266	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VCSRO63_2267	COG3091	SprT-like family
VCSRO63_2268	COG2356	endonuclease I
VCSRO63_2269	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VCSRO63_2270	COG0189	ligase activity
VCSRO63_2271	COG1678	Uncharacterized ACR, COG1678
VCSRO63_2272	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VCSRO63_2273	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCSRO63_2277	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VCSRO63_2278	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VCSRO63_2279	COG0762	integral membrane protein
VCSRO63_2282	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VCSRO63_2283	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VCSRO63_2284	COG2066	Belongs to the glutaminase family
VCSRO63_2285	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VCSRO63_2286	COG1194	a g-specific adenine glycosylase
VCSRO63_2287	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VCSRO63_2288	COG0741	lytic transglycosylase activity
VCSRO63_2299	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VCSRO63_2300	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VCSRO63_2301	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO63_2302	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VCSRO63_2303	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VCSRO63_2304	COG2967	ApaG domain
VCSRO63_2305	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VCSRO63_2307	COG3610	response to peptide
VCSRO63_2308	COG2966	Psort location CytoplasmicMembrane, score
VCSRO63_2309	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VCSRO63_2310	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VCSRO63_2311	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VCSRO63_2312	COG0142	geranyltranstransferase activity
VCSRO63_2313	COG0531	amino acid
VCSRO63_2314	COG0039	L-malate dehydrogenase activity
VCSRO63_2315	COG1438	arginine binding
VCSRO63_2316	COG2358	TRAP transporter, solute receptor (TAXI family
VCSRO63_2318	COG0589	response to stress
VCSRO63_2323	COG2235	arginine
VCSRO63_2324	COG0312	modulator of DNA gyrase
VCSRO63_2325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VCSRO63_2326	COG3164	Protein of unknown function
VCSRO63_2328	COG0424	maF-like protein
VCSRO63_2329	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VCSRO63_2330	COG1792	Involved in formation and maintenance of cell shape
VCSRO63_2331	COG1077	Cell shape determining protein MreB Mrl
VCSRO63_2337	COG2165	general secretion pathway protein
VCSRO63_2338	COG2165	general secretion pathway protein
VCSRO63_2340	COG1459	type II secretion system
VCSRO63_2341	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO63_2343	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO63_2343	COG3267	Type II secretory pathway component ExeA
VCSRO63_2348	COG2200	EAL domain
VCSRO63_2348	COG2199	diguanylate cyclase activity
VCSRO63_2349	COG0629	single-stranded DNA binding
VCSRO63_2352	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VCSRO63_2354	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCSRO63_2355	COG0527	aspartate kinase activity
VCSRO63_2356	COG0646	methionine synthase
VCSRO63_2356	COG1410	methionine synthase
VCSRO63_2370	COG0175	sulfate reduction
VCSRO63_2371	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VCSRO63_2372	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCSRO63_2376	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO63_2377	COG0735	belongs to the Fur family
VCSRO63_2381	COG0432	Pfam Uncharacterised protein family UPF0047
VCSRO63_2382	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCSRO63_2385	COG0359	binds to the 23S rRNA
VCSRO63_2386	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
VCSRO63_2387	COG2965	DNA replication, synthesis of RNA primer
VCSRO63_2388	COG0360	Binds together with S18 to 16S ribosomal RNA
VCSRO63_2390	COG2906	2 iron, 2 sulfur cluster binding
VCSRO63_2391	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCSRO63_2392	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCSRO63_2393	COG0049	tRNA binding
VCSRO63_2396	COG2923	Belongs to the DsrF TusC family
VCSRO63_2397	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VCSRO63_2398	COG2964	Protein conserved in bacteria
VCSRO63_2399	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO63_2401	COG2900	Belongs to the SlyX family
VCSRO63_2402	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VCSRO63_2403	COG0330	HflC and HflK could
VCSRO63_2404	COG0330	HflC and HflK could
VCSRO63_2405	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VCSRO63_2406	COG1923	regulation of RNA biosynthetic process
VCSRO63_2407	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VCSRO63_2408	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VCSRO63_2410	COG0802	atpase or kinase
VCSRO63_2411	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VCSRO63_2421	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VCSRO63_2422	COG1162	GTPase activity
VCSRO63_2423	COG0688	phosphatidylethanolamine metabolic process
VCSRO63_2424	COG0471	metal ion transport
VCSRO63_2426	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VCSRO63_2427	COG4942	peptidase
VCSRO63_2430	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VCSRO63_2431	COG2816	NAD+ diphosphatase activity
VCSRO63_2433	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VCSRO63_2434	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VCSRO63_2435	COG0085	RNA polymerase activity
VCSRO63_2436	COG0222	ribosome binding
VCSRO63_2437	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VCSRO63_2439	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VCSRO63_2440	COG0250	Participates in transcription elongation, termination and antitermination
VCSRO63_2441	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCSRO63_2446	COG1072	(Pantothenic acid kinase))
VCSRO63_2448	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VCSRO63_2450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VCSRO63_2459	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VCSRO63_2462	COG3118	belongs to the thioredoxin family
VCSRO63_2463	COG0513	Belongs to the DEAD box helicase family
VCSRO63_2464	COG0248	Ppx GppA phosphatase
VCSRO63_2465	COG2205	protein histidine kinase activity
VCSRO63_2465	COG0784	Response regulator, receiver
VCSRO63_2466	COG2814	Major facilitator Superfamily
VCSRO63_2469	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCSRO63_2470	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VCSRO63_2471	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO63_2472	COG0439	Biotin carboxylase
VCSRO63_2473	COG2264	protein methyltransferase activity
VCSRO63_2474	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO63_2475	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VCSRO63_2476	COG1609	Transcriptional regulator
VCSRO63_2478	COG0387	Pfam Sodium calcium exchanger
VCSRO63_2479	COG0129	dihydroxy-acid dehydratase activity
VCSRO63_2480	COG3265	gluconokinase activity
VCSRO63_2482	COG0800	Aldolase
VCSRO63_2485	COG0840	transmembrane signaling receptor activity
VCSRO63_2486	COG1982	Orn Lys Arg decarboxylase major
VCSRO63_2487	COG0531	amino acid
VCSRO63_2488	COG3710	Transcriptional regulator
VCSRO63_2489	COG0789	Transcriptional regulator
VCSRO63_2491	COG0151	Belongs to the GarS family
VCSRO63_2493	COG0776	regulation of translation
VCSRO63_2494	COG1253	flavin adenine dinucleotide binding
VCSRO63_2495	COG1940	carbohydrate kinase activity
VCSRO63_2497	COG3068	Protein conserved in bacteria
VCSRO63_2499	COG1573	uracil-dna glycosylase
VCSRO63_2500	COG0668	transmembrane transport
VCSRO63_2503	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VCSRO63_2504	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCSRO63_2509	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCSRO63_2510	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
VCSRO63_2514	COG0546	phosphoglycolate phosphatase activity
VCSRO63_2521	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCSRO63_2522	COG0662	Cupin 2, conserved barrel domain protein
VCSRO63_2522	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
VCSRO63_2523	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCSRO63_2527	COG0859	PFAM glycosyl transferase family 9
VCSRO63_2529	COG1519	Transferase
VCSRO63_2532	COG3642	lipopolysaccharide core region biosynthetic process
VCSRO63_2533	COG1442	glycosyl transferase family 8
VCSRO63_2534	COG0859	PFAM glycosyl transferase family 9
VCSRO63_2535	COG0463	Glycosyl transferase, family 2
VCSRO63_2536	COG0859	PFAM glycosyl transferase family 9
VCSRO63_2537	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VCSRO63_2538	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VCSRO63_2540	COG0267	Belongs to the bacterial ribosomal protein bL33 family
VCSRO63_2541	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VCSRO63_2542	COG2003	Belongs to the UPF0758 family
VCSRO63_2544	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VCSRO63_2545	COG1309	transcriptional regulator
VCSRO63_2546	COG1560	Kdo2-lipid A biosynthetic process
VCSRO63_2547	COG1560	Kdo2-lipid A biosynthetic process
VCSRO63_2548	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VCSRO63_2549	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VCSRO63_2550	COG1561	YicC-like family, N-terminal region
VCSRO63_2551	COG2862	Uncharacterized protein family, UPF0114
VCSRO63_2552	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO63_2552	COG1263	PTS System
VCSRO63_2553	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCSRO63_2557	COG1120	ATPase activity
VCSRO63_2558	COG4774	siderophore transport
VCSRO63_2559	COG1132	(ABC) transporter
VCSRO63_2562	COG0514	ATP-dependent DNA helicase (RecQ)
VCSRO63_2563	COG2962	Rard protein
VCSRO63_2564	COG0405	Gamma-glutamyltransferase
VCSRO63_2566	COG1280	lysine exporter protein (LysE YggA)
VCSRO63_2567	COG0210	DNA helicase
VCSRO63_2569	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VCSRO63_2570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO63_2572	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO63_2573	COG0601	transmembrane transport
VCSRO63_2574	COG0747	negative chemotaxis
VCSRO63_2583	COG1309	transcriptional regulator
VCSRO63_2584	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO63_2585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO63_2586	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO63_2587	COG2960	long-chain fatty acid transporting porin activity
VCSRO63_2588	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VCSRO63_2589	COG0583	DNA-binding transcription factor activity
VCSRO63_2602	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
VCSRO63_2603	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCSRO63_2604	COG1739	Uncharacterized protein family UPF0029
VCSRO63_2605	COG1024	Enoyl-CoA hydratase
VCSRO63_2605	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCSRO63_2606	COG0183	Belongs to the thiolase family
VCSRO63_2607	COG0583	DNA-binding transcription factor activity
VCSRO63_2608	COG2814	Major facilitator Superfamily
VCSRO63_2610	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VCSRO63_2611	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VCSRO63_2612	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VCSRO63_2613	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VCSRO63_2614	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VCSRO63_2615	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VCSRO63_2617	COG0356	it plays a direct role in the translocation of protons across the membrane
VCSRO63_2618	COG3312	ion transport
VCSRO63_2619	COG1475	DNA binding
VCSRO63_2620	COG1192	Involved in chromosome partitioning
VCSRO63_2621	COG0357	Ribosomal RNA small subunit methyltransferase G
VCSRO63_2622	COG0445	tRNA wobble uridine modification
VCSRO63_2627	COG0217	transcriptional regulatory protein
VCSRO63_2628	COG2084	Dehydrogenase
VCSRO63_2631	COG2909	trisaccharide binding
VCSRO63_2632	COG0058	SHG alpha-glucan phosphorylase activity
VCSRO63_2633	COG1640	4-alpha-glucanotransferase
VCSRO63_2634	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VCSRO63_2636	COG3501	Rhs element vgr protein
VCSRO63_2637	COG4104	PAAR repeat-containing protein
VCSRO63_2643	COG0471	metal ion transport
VCSRO63_2644	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCSRO63_2652	COG0671	phosphoesterase, PA-phosphatase related
VCSRO63_2653	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VCSRO63_2655	COG1999	signal sequence binding
VCSRO63_2658	COG0786	glutamate:sodium symporter activity
VCSRO63_2662	COG1566	PFAM secretion protein HlyD family protein
VCSRO63_2667	COG0813	purine-nucleoside phosphorylase activity
VCSRO63_2668	COG3272	Protein of unknown function (DUF1722)
VCSRO63_2670	COG0415	Belongs to the DNA photolyase family
VCSRO63_2671	COG1376	ErfK ybiS ycfS ynhG family protein
VCSRO63_2671	COG1388	LysM domain
VCSRO63_2673	COG0513	Belongs to the DEAD box helicase family
VCSRO63_2674	COG1770	oligopeptidase
VCSRO63_2675	COG4771	TonB-dependent receptor
VCSRO63_2680	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCSRO63_2681	COG0573	inorganic phosphate transmembrane transporter activity
VCSRO63_2682	COG0581	inorganic phosphate transmembrane transporter activity
VCSRO63_2683	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCSRO63_2686	COG3314	Sporulation integral membrane protein YlbJ
VCSRO63_2687	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO63_2689	COG0739	heme binding
VCSRO63_2690	COG5001	Diguanylate cyclase
VCSRO63_2690	COG3300	MHYT domain
VCSRO63_2692	COG0583	DNA-binding transcription factor activity
VCSRO63_2693	COG2814	Major facilitator Superfamily
VCSRO63_2698	COG1301	dicarboxylic acid transport
VCSRO63_2700	COG1342	Belongs to the UPF0251 family
VCSRO63_2705	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VCSRO63_2706	COG0673	inositol 2-dehydrogenase activity
VCSRO63_2708	COG2200	EAL domain
VCSRO63_2708	COG2771	luxR family
VCSRO63_2709	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO63_2711	COG0564	pseudouridine synthase activity
VCSRO63_2724	COG3829	transcription factor binding
VCSRO63_2729	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO63_2729	COG3501	Rhs element vgr protein
VCSRO63_2732	COG1869	D-ribose catabolic process
VCSRO63_2733	COG1129	ABC transporter
VCSRO63_2734	COG1172	Belongs to the binding-protein-dependent transport system permease family
VCSRO63_2735	COG1879	ABC-type sugar transport system periplasmic component
VCSRO63_2736	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO63_2737	COG1609	Transcriptional regulator
VCSRO63_2738	COG3447	MASE1 domain protein
VCSRO63_2738	COG5001	Diguanylate cyclase
VCSRO63_2738	COG5002	protein histidine kinase activity
VCSRO63_2740	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO63_2742	COG0584	glycerophosphoryl diester phosphodiesterase
VCSRO63_2743	COG2271	Major facilitator Superfamily
VCSRO63_2750	COG0579	oxidoreductase
VCSRO63_2752	COG0242	peptide deformylase activity
VCSRO63_2754	COG1320	monovalent cation:proton antiporter activity
VCSRO63_2755	COG2212	antiporter activity
VCSRO63_2756	COG1863	multisubunit Na H antiporter MnhE subunit
VCSRO63_2757	COG0651	ATP synthesis coupled electron transport
VCSRO63_2758	COG1006	Multisubunit Na H antiporter MnhC subunit
VCSRO63_2759	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCSRO63_2759	COG2111	Na H antiporter
VCSRO63_2761	COG0589	response to stress
VCSRO63_2762	COG0814	amino acid
VCSRO63_2765	COG3530	Putative quorum-sensing-regulated virulence factor
VCSRO63_2767	COG5001	Diguanylate cyclase
VCSRO63_2767	COG5002	protein histidine kinase activity
VCSRO63_2768	COG1278	Cold shock
VCSRO63_2771	COG2304	oxidoreductase activity
VCSRO63_2775	COG0714	Associated with various cellular activities
VCSRO63_2776	COG0840	transmembrane signaling receptor activity
VCSRO63_2779	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO63_2780	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO63_2782	COG3604	Transcriptional regulator
VCSRO63_2783	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCSRO63_2783	COG1017	nitric oxide dioxygenase activity
VCSRO63_2784	COG1278	Cold shock
VCSRO63_2785	COG3036	rescue of stalled ribosome
VCSRO63_2790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VCSRO63_2790	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VCSRO63_2791	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCSRO63_2793	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCSRO63_2795	COG0516	GMP reductase activity
VCSRO63_2797	COG0513	Belongs to the DEAD box helicase family
VCSRO63_2798	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCSRO63_2799	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VCSRO63_2800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VCSRO63_2801	COG0784	Response regulator, receiver
VCSRO63_2801	COG3437	response regulator, receiver
VCSRO63_2802	COG4191	Histidine kinase
VCSRO63_2802	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO63_2804	COG1757	Na H antiporter
VCSRO63_2805	COG2814	Major facilitator Superfamily
VCSRO63_2806	COG3706	GGDEF domain
VCSRO63_2807	COG3240	lipase activity
VCSRO63_2809	COG0840	transmembrane signaling receptor activity
VCSRO63_2810	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VCSRO63_2811	COG5380	lipid catabolic process
VCSRO63_2816	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO63_2817	COG4605	iron ion homeostasis
VCSRO63_2818	COG4604	ABC transporter, ATP-binding protein
VCSRO63_2819	COG2207	Transcriptional regulator
VCSRO63_2822	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCSRO63_2823	COG3385	transposase activity
VCSRO63_2828	COG0745	RESPONSE REGULATOR receiver
VCSRO63_2830	COG3623	hexulose-6-phosphate isomerase
VCSRO63_2831	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
VCSRO63_2832	COG0561	phosphatase activity
VCSRO63_2839	COG0366	Alpha amylase catalytic
VCSRO63_2843	COG0745	RESPONSE REGULATOR receiver
VCSRO63_2844	COG5002	protein histidine kinase activity
VCSRO63_2847	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO63_2854	COG1686	Belongs to the peptidase S11 family
VCSRO63_2859	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCSRO63_2859	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCSRO63_2860	COG0509	glycine decarboxylation via glycine cleavage system
VCSRO63_2861	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCSRO63_2863	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VCSRO63_2866	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VCSRO63_2867	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
VCSRO63_2877	COG0456	acetyltransferase
VCSRO63_2879	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO63_2879	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO63_2882	COG0494	nUDIX hydrolase
VCSRO63_2891	COG0384	phenazine biosynthesis protein PhzF
VCSRO63_2893	COG0494	nUDIX hydrolase
VCSRO63_2894	COG2161	toxin-antitoxin pair type II binding
VCSRO63_2895	COG4115	mRNA cleavage
VCSRO63_2898	COG3040	lipid binding
VCSRO63_2904	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO63_2905	COG0456	acetyltransferase
VCSRO63_2914	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
VCSRO63_2918	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
VCSRO63_2925	COG1619	proteins homologs of microcin C7 resistance protein MccF
VCSRO63_2939	COG4977	sequence-specific DNA binding
VCSRO63_2952	COG1418	mRNA catabolic process
VCSRO63_2975	COG0456	acetyltransferase
VCSRO63_2976	COG0456	acetyltransferase
VCSRO63_2984	COG3549	Plasmid maintenance system killer
VCSRO63_2985	COG3093	addiction module antidote protein HigA
VCSRO63_2986	COG3040	lipid binding
VCSRO63_2992	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO63_2992	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO63_3002	COG0494	nUDIX hydrolase
VCSRO63_3012	COG0454	-acetyltransferase
VCSRO63_3029	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO63_3030	COG0384	phenazine biosynthesis protein PhzF
VCSRO63_3032	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO63_3047	COG1619	proteins homologs of microcin C7 resistance protein MccF
VCSRO63_3049	COG2801	Transposase and inactivated derivatives
VCSRO63_3051	COG1328	CTP reductase activity
VCSRO63_3052	COG0602	queuosine metabolic process
VCSRO63_3054	COG0189	ligase activity
VCSRO63_3054	COG4067	protein conserved in archaea
VCSRO63_3055	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VCSRO63_3055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO63_3055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO63_3056	COG1105	Belongs to the carbohydrate kinase PfkB family
VCSRO63_3057	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO63_3057	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO63_3058	COG1609	Transcriptional regulator
VCSRO63_3059	COG0420	3'-5' exonuclease activity
VCSRO63_3060	COG0419	ATPase involved in DNA repair
VCSRO63_3061	COG2205	protein histidine kinase activity
VCSRO63_3061	COG0784	Response regulator, receiver
VCSRO63_3062	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO63_3064	COG0038	chloride channel
VCSRO63_3065	COG0523	cobalamin synthesis protein
VCSRO63_3067	COG3158	transport of potassium into the cell
VCSRO63_3068	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VCSRO63_3068	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
VCSRO63_3068	COG1013	pyruvate-flavodoxin oxidoreductase activity
VCSRO63_3068	COG0674	pyruvate-flavodoxin oxidoreductase activity
VCSRO63_3069	COG2205	protein histidine kinase activity
VCSRO63_3070	COG0745	RESPONSE REGULATOR receiver
VCSRO63_3071	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO63_3072	COG0586	Pfam SNARE associated Golgi protein
VCSRO63_3074	COG2200	EAL domain
VCSRO63_3076	COG3038	cytochrome b561
VCSRO63_3078	COG2116	formate transmembrane transporter activity
VCSRO63_3079	COG0583	DNA-binding transcription factor activity
VCSRO63_3081	COG3593	DNA synthesis involved in DNA repair
VCSRO63_3082	COG0737	Belongs to the 5'-nucleotidase family
VCSRO63_3085	COG2824	Alkylphosphonate utilization operon protein PhnA
VCSRO63_3091	COG2199	diguanylate cyclase activity
VCSRO63_3095	COG3706	GGDEF domain
VCSRO63_3098	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VCSRO63_3099	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VCSRO63_3101	COG0745	RESPONSE REGULATOR receiver
VCSRO63_3104	COG3140	Belongs to the UPF0181 family
VCSRO63_3105	COG0023	Translation Initiation Factor
VCSRO63_3109	COG1042	CoA-binding domain protein
VCSRO63_3109	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO63_3109	COG0045	succinate-CoA ligase (ADP-forming) activity
VCSRO63_3110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO63_3110	COG1042	CoA-binding domain protein
VCSRO63_3110	COG0045	succinate-CoA ligase (ADP-forming) activity
VCSRO63_3111	COG0583	DNA-binding transcription factor activity
VCSRO63_3112	COG4771	TonB-dependent receptor
VCSRO63_3115	COG2050	protein possibly involved in aromatic compounds catabolism
VCSRO63_3119	COG0625	glutathione transferase activity
VCSRO63_3122	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VCSRO63_3123	COG4172	Belongs to the ABC transporter superfamily
VCSRO63_3124	COG4239	(ABC) transporter, permease
VCSRO63_3125	COG4174	ABC transporter (Permease)
VCSRO63_3126	COG4166	transmembrane transport
VCSRO63_3131	COG3104	oligopeptide transport
VCSRO63_3135	COG3842	ATPase activity
VCSRO63_3136	COG1840	ABC-type Fe3 transport system, periplasmic component
VCSRO63_3137	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCSRO63_3138	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VCSRO63_3139	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO63_3140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO63_3141	COG1011	Hydrolase
VCSRO63_3143	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VCSRO63_3144	COG1970	mechanosensitive ion channel activity
VCSRO63_3145	COG2759	Belongs to the formate--tetrahydrofolate ligase family
VCSRO63_3146	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO63_3146	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO63_3147	COG0302	gtp cyclohydrolase
VCSRO63_3149	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCSRO63_3151	COG2897	thiosulfate sulfurtransferase activity
VCSRO63_3152	COG2390	Transcriptional regulator
VCSRO63_3154	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCSRO63_3155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCSRO63_3160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO63_3165	COG0583	DNA-binding transcription factor activity
VCSRO63_3166	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
VCSRO63_3174	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCSRO63_3183	COG1263	PTS System
VCSRO63_3183	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO63_3184	COG1609	Transcriptional regulator
VCSRO63_3185	COG1621	beta-fructofuranosidase activity
VCSRO63_3186	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO63_3187	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCSRO63_3189	COG2885	chlorophyll binding
VCSRO63_3190	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO63_3191	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO63_3192	COG0840	transmembrane signaling receptor activity
VCSRO63_3193	COG3069	C4-dicarboxylate transmembrane transporter activity
VCSRO63_3194	COG1760	l-serine dehydratase
VCSRO63_3198	COG1609	Transcriptional regulator
VCSRO63_3199	COG2197	response regulator
VCSRO63_3200	COG3850	Histidine kinase
VCSRO63_3201	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCSRO63_3203	COG0243	molybdopterin cofactor binding
VCSRO63_3207	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO63_3208	COG2197	response regulator
VCSRO63_3209	COG3851	Histidine kinase
VCSRO63_3210	COG2271	Major facilitator Superfamily
VCSRO63_3211	COG1840	ABC-type Fe3 transport system, periplasmic component
VCSRO63_3213	COG3842	ATPase activity
VCSRO63_3214	COG3243	poly(R)-hydroxyalkanoic acid synthase
VCSRO63_3216	COG0183	Belongs to the thiolase family
VCSRO63_3218	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO63_3219	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO63_3223	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCSRO63_3225	COG1979	alcohol dehydrogenase
VCSRO63_3228	COG4191	Histidine kinase
VCSRO63_3231	COG2271	Major facilitator Superfamily
VCSRO63_3232	COG0469	pyruvate kinase activity
VCSRO63_3233	COG2198	Histidine kinase
VCSRO63_3233	COG2205	protein histidine kinase activity
VCSRO63_3233	COG0784	Response regulator, receiver
VCSRO63_3234	COG1879	ABC-type sugar transport system periplasmic component
VCSRO63_3235	COG1803	Methylglyoxal synthase
VCSRO63_3236	COG1335	isochorismatase
VCSRO63_3237	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VCSRO63_3240	COG0210	DNA helicase
VCSRO63_3241	COG1289	transmembrane transporter activity
VCSRO63_3247	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
VCSRO63_3248	COG4149	molybdate abc transporter
VCSRO63_3249	COG0725	ABC transporter, periplasmic molybdate-binding protein
VCSRO63_3250	COG1492	cobalamin metabolic process
VCSRO63_3251	COG0210	DNA helicase
VCSRO63_3257	COG0784	Response regulator, receiver
VCSRO63_3257	COG5002	protein histidine kinase activity
VCSRO63_3258	COG1879	ABC-type sugar transport system periplasmic component
VCSRO63_3260	COG2827	Endonuclease containing a URI domain
VCSRO63_3263	COG2926	Belongs to the UPF0265 family
VCSRO63_3267	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VCSRO63_3268	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCSRO63_3269	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
VCSRO63_3270	COG0247	lactate metabolic process
VCSRO63_3271	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCSRO63_3272	COG3118	belongs to the thioredoxin family
VCSRO63_3278	COG0583	DNA-binding transcription factor activity
VCSRO63_3279	COG4160	amino acid transport
VCSRO63_3280	COG4215	(ABC) transporter
VCSRO63_3281	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO63_3282	COG1126	abc transporter atp-binding protein
VCSRO63_3284	COG2425	protein containing a von Willebrand factor type A (vWA) domain
VCSRO63_3286	COG0494	nUDIX hydrolase
VCSRO63_3287	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VCSRO63_3289	COG1309	transcriptional regulator
VCSRO63_3290	COG0513	Belongs to the DEAD box helicase family
VCSRO63_3291	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
VCSRO63_3293	COG0814	amino acid
VCSRO63_3294	COG0840	transmembrane signaling receptor activity
VCSRO63_3295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VCSRO63_3296	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
VCSRO63_3298	COG1984	allophanate hydrolase subunit 2
VCSRO63_3301	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VCSRO63_3302	COG4181	ATPase activity
VCSRO63_3304	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCSRO63_3305	COG5001	Diguanylate cyclase
VCSRO63_3305	COG1716	ATPase activity
VCSRO63_3307	COG0484	heat shock protein binding
VCSRO63_3311	COG0546	phosphoglycolate phosphatase activity
VCSRO63_3314	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO63_3315	COG1368	sulfuric ester hydrolase activity
VCSRO63_3317	COG0513	Belongs to the DEAD box helicase family
VCSRO63_3320	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCSRO63_3322	COG3046	protein related to deoxyribodipyrimidine photolyase
VCSRO63_3323	COG3397	chitin binding
VCSRO63_3324	COG3227	Zinc metalloprotease (Elastase)
VCSRO63_3326	COG0010	Belongs to the arginase family
VCSRO63_3327	COG1166	arginine decarboxylase activity
VCSRO63_3329	COG2239	Acts as a magnesium transporter
VCSRO63_3330	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCSRO63_3331	COG0459	protein refolding
VCSRO63_3333	COG0527	aspartate kinase activity
VCSRO63_3334	COG0662	Cupin 2, conserved barrel domain protein
VCSRO63_3335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VCSRO63_3336	COG0456	acetyltransferase
VCSRO63_3338	COG2154	pterin-4-alpha-carbinolamine dehydratase
VCSRO63_3339	COG3186	Phenylalanine-4-hydroxylase
VCSRO63_3340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCSRO63_3343	COG2264	protein methyltransferase activity
VCSRO63_3348	COG1253	flavin adenine dinucleotide binding
VCSRO63_3349	COG1765	OsmC-like protein
VCSRO63_3354	COG0531	amino acid
VCSRO63_3357	COG3279	Response regulator of the LytR AlgR family
VCSRO63_3358	COG3275	phosphorelay sensor kinase activity
VCSRO63_3361	COG0577	efflux transmembrane transporter activity
VCSRO63_3361	COG1136	(ABC) transporter
VCSRO63_3362	COG1136	(ABC) transporter
VCSRO63_3364	COG4989	oxidoreductase activity
VCSRO63_3365	COG0366	Alpha amylase catalytic
VCSRO63_3366	COG2067	long-chain fatty acid transport protein
VCSRO63_3367	COG2267	carboxylic ester hydrolase activity
VCSRO63_3369	COG3227	Zinc metalloprotease (Elastase)
VCSRO63_3370	COG3047	cAMP biosynthetic process
VCSRO63_3373	COG1686	Belongs to the peptidase S11 family
VCSRO63_3374	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VCSRO63_3375	COG1271	oxidase subunit
VCSRO63_3376	COG1294	oxidase, subunit
VCSRO63_3379	COG3048	D-serine ammonia-lyase activity
VCSRO63_3380	COG0583	DNA-binding transcription factor activity
VCSRO63_3391	COG1337	RAMP superfamily
VCSRO63_3417	COG0571	ribonuclease III activity
VCSRO63_3421	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VCSRO63_3422	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VCSRO63_3427	COG1802	Transcriptional regulator
VCSRO63_3427	COG4626	Terminase
VCSRO63_3434	COG0582	viral genome integration into host DNA
VCSRO63_3435	COG0640	Transcriptional regulator
VCSRO63_3436	COG0798	PFAM Bile acid sodium symporter
VCSRO63_3438	COG1063	alcohol dehydrogenase
VCSRO63_3439	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO63_3444	COG0346	lactoylglutathione lyase activity
VCSRO63_3448	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
VCSRO63_3449	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO63_3450	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VCSRO63_3451	COG0363	glucosamine-6-phosphate deaminase activity
VCSRO63_3452	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VCSRO63_3457	COG1929	Belongs to the glycerate kinase type-1 family
VCSRO63_3458	COG2610	gluconate transmembrane transporter activity
VCSRO63_3459	COG3835	regulator
VCSRO63_3461	COG0748	coenzyme F420 binding
VCSRO63_3462	COG3721	Heme iron utilization protein
VCSRO63_3464	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCSRO63_3465	COG0811	peptide transport
VCSRO63_3466	COG0848	biopolymer transport protein
VCSRO63_3467	COG4558	Periplasmic binding protein
VCSRO63_3468	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO63_3469	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VCSRO63_3476	COG3217	Mosc domain protein beta barrel domain protein
VCSRO63_3476	COG0633	Ferredoxin
VCSRO63_3476	COG3217	Mosc domain protein beta barrel domain protein
VCSRO63_3476	COG0633	Ferredoxin
VCSRO63_3477	COG0418	dihydroorotase activity
VCSRO63_3479	COG3152	Membrane
VCSRO63_3481	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCSRO63_3482	COG2354	Protein conserved in bacteria
VCSRO63_3483	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO63_3484	COG1278	Cold shock
VCSRO63_3489	COG2199	diguanylate cyclase activity
VCSRO63_3490	COG1349	DNA-binding transcription factor activity
VCSRO63_3493	COG3833	ABC-type maltose transport systems, permease component
VCSRO63_3494	COG1175	transmembrane transport
VCSRO63_3496	COG3842	ATPase activity
VCSRO63_3497	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO63_3500	COG0393	Putative heavy-metal-binding
VCSRO63_3502	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO63_3503	COG0784	Response regulator, receiver
VCSRO63_3503	COG0835	chemotaxis
VCSRO63_3504	COG1846	Transcriptional regulator
VCSRO63_3505	COG3706	GGDEF domain
VCSRO63_3512	COG0583	DNA-binding transcription factor activity
VCSRO63_3513	COG5001	Diguanylate cyclase
VCSRO63_3515	COG1741	Belongs to the pirin family
VCSRO63_3516	COG3123	guanosine phosphorylase activity
VCSRO63_3518	COG2211	Major facilitator Superfamily
VCSRO63_3520	COG0840	transmembrane signaling receptor activity
VCSRO63_3521	COG1067	ATP-dependent peptidase activity
VCSRO63_3523	COG4172	Belongs to the ABC transporter superfamily
VCSRO63_3527	COG0583	DNA-binding transcription factor activity
VCSRO63_3528	COG1620	l-lactate permease
VCSRO63_3531	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
VCSRO63_3533	COG0840	transmembrane signaling receptor activity
VCSRO63_3537	COG2258	MOSC domain
VCSRO63_3538	COG0513	Belongs to the DEAD box helicase family
VCSRO63_3540	COG2186	Transcriptional regulator
VCSRO63_3542	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCSRO63_3544	COG0246	Mannitol dehydrogenase
VCSRO63_3545	COG1904	glucuronate isomerase
VCSRO63_3546	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO63_3547	COG0800	Aldolase
VCSRO63_3549	COG0583	DNA-binding transcription factor activity
VCSRO63_3551	COG1902	pentaerythritol trinitrate reductase activity
VCSRO63_3553	COG1132	(ABC) transporter
VCSRO63_3555	COG1902	pentaerythritol trinitrate reductase activity
VCSRO63_3557	COG1280	lysine exporter protein (LysE YggA)
VCSRO63_3558	COG2207	Transcriptional regulator
VCSRO63_3562	COG1846	Transcriptional regulator
VCSRO63_3563	COG1764	response to oxidative stress
VCSRO63_3564	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCSRO63_3565	COG0697	spore germination
VCSRO63_3567	COG0700	Nucleoside recognition
VCSRO63_3568	COG3366	ferrous iron transmembrane transporter activity
VCSRO63_3569	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
VCSRO63_3570	COG4565	transcriptional regulatory protein
VCSRO63_3572	COG0471	metal ion transport
VCSRO63_3574	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VCSRO63_3575	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
VCSRO63_3576	COG2259	Doxx family
VCSRO63_3581	COG0363	glucosamine-6-phosphate deaminase activity
VCSRO63_3584	COG4580	involved in the transport of maltose and maltodextrins
VCSRO63_3587	COG0840	transmembrane signaling receptor activity
VCSRO63_3590	COG0840	transmembrane signaling receptor activity
VCSRO63_3592	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO63_3593	COG1126	abc transporter atp-binding protein
VCSRO63_3595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO63_3596	COG4597	amino acid ABC transporter
VCSRO63_3597	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCSRO63_3598	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO63_3598	COG2213	PTS system mannitol-specific
VCSRO63_3599	COG0246	Mannitol dehydrogenase
VCSRO63_3600	COG3722	fumarate hydratase activity
VCSRO63_3601	COG0673	inositol 2-dehydrogenase activity
VCSRO63_3607	COG2910	NAD(P)H-binding
VCSRO63_3609	COG0840	transmembrane signaling receptor activity
VCSRO63_3610	COG4221	oxidoreductase activity
VCSRO63_3613	COG1901	pseudouridine methyltransferase
VCSRO63_3615	COG0531	amino acid
VCSRO63_3616	COG1982	Orn Lys Arg decarboxylase major
VCSRO63_3621	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCSRO63_3626	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VCSRO63_3634	COG0745	RESPONSE REGULATOR receiver
VCSRO63_3639	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCSRO63_3640	COG0840	transmembrane signaling receptor activity
VCSRO63_3641	COG0835	chemotaxis
VCSRO63_3642	COG0835	chemotaxis
VCSRO63_3643	COG2198	Histidine kinase
VCSRO63_3643	COG0643	Histidine kinase
VCSRO63_3647	COG0601	transmembrane transport
VCSRO63_3648	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO63_3649	COG4608	Belongs to the ABC transporter superfamily
VCSRO63_3650	COG2194	sulfuric ester hydrolase activity
VCSRO63_3651	COG0642	Histidine kinase
VCSRO63_3658	COG1444	tRNA N-acetyltransferase activity
VCSRO63_3659	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine