locus-tag	class	description
VCSRO77_0001	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCSRO77_0002	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
VCSRO77_0003	COG0706	membrane insertase activity
VCSRO77_0004	COG0594	ribonuclease P activity
VCSRO77_0005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VCSRO77_0006	COG1126	abc transporter atp-binding protein
VCSRO77_0009	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VCSRO77_0010	COG0592	DNA-directed DNA polymerase activity
VCSRO77_0011	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VCSRO77_0012	COG0187	DNA topoisomerase II activity
VCSRO77_0015	COG0071	Belongs to the small heat shock protein (HSP20) family
VCSRO77_0016	COG3977	Valine--pyruvate aminotransferase
VCSRO77_0017	COG0751	glycine-tRNA ligase activity
VCSRO77_0018	COG0752	glycyl-tRNA synthetase alpha subunit
VCSRO77_0019	COG2119	membrane
VCSRO77_0021	COG0425	Belongs to the sulfur carrier protein TusA family
VCSRO77_0023	COG0604	alcohol dehydrogenase
VCSRO77_0025	COG0129	dihydroxy-acid dehydratase activity
VCSRO77_0026	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCSRO77_0029	COG0606	chelatase, subunit chli
VCSRO77_0030	COG0204	Acyl-transferase
VCSRO77_0031	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCSRO77_0032	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VCSRO77_0034	COG3084	Protein conserved in bacteria
VCSRO77_0036	COG4326	sporulation control protein
VCSRO77_0037	COG1272	protein, Hemolysin III
VCSRO77_0039	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCSRO77_0040	COG0569	domain protein
VCSRO77_0041	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VCSRO77_0041	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCSRO77_0042	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VCSRO77_0043	COG0242	peptide deformylase activity
VCSRO77_0044	COG1652	LysM domain
VCSRO77_0045	COG0758	DNA mediated transformation
VCSRO77_0046	COG2922	Belongs to the Smg family
VCSRO77_0047	COG0551	DNA topoisomerase type I activity
VCSRO77_0048	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VCSRO77_0049	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VCSRO77_0050	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO77_0051	COG0408	coproporphyrinogen oxidase activity
VCSRO77_0052	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VCSRO77_0054	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VCSRO77_0062	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VCSRO77_0063	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VCSRO77_0065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCSRO77_0066	COG2104	thiamine diphosphate biosynthetic process
VCSRO77_0067	COG2022	thiamine diphosphate biosynthetic process
VCSRO77_0068	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCSRO77_0069	COG0006	proline dipeptidase activity
VCSRO77_0069	COG0006	proline dipeptidase activity
VCSRO77_0073	COG1522	sequence-specific DNA binding
VCSRO77_0074	COG5001	Diguanylate cyclase
VCSRO77_0074	COG5002	protein histidine kinase activity
VCSRO77_0078	COG0589	response to stress
VCSRO77_0079	COG1528	Iron-storage protein
VCSRO77_0081	COG2081	HI0933 family
VCSRO77_0083	COG1322	Protein conserved in bacteria
VCSRO77_0084	COG2226	methyltransferase
VCSRO77_0087	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO77_0088	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO77_0089	COG0805	protein transport
VCSRO77_0090	COG0534	Mate efflux family protein
VCSRO77_0092	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VCSRO77_0093	COG2937	Belongs to the GPAT DAPAT family
VCSRO77_0094	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VCSRO77_0095	COG3161	chorismate lyase activity
VCSRO77_0096	COG1580	Controls the rotational direction of flagella during chemotaxis
VCSRO77_0097	COG0840	transmembrane signaling receptor activity
VCSRO77_0099	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO77_0100	COG0084	hydrolase, TatD family'
VCSRO77_0103	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO77_0103	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO77_0107	COG3078	GTPase activator activity
VCSRO77_0110	COG3071	HemY protein
VCSRO77_0111	COG2959	enzyme of heme biosynthesis
VCSRO77_0112	COG1587	Uroporphyrinogen-III synthase
VCSRO77_0113	COG0181	hydroxymethylbilane synthase activity
VCSRO77_0115	COG1965	Belongs to the frataxin family
VCSRO77_0116	COG0019	diaminopimelate decarboxylase activity
VCSRO77_0117	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VCSRO77_0119	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VCSRO77_0120	COG1011	Hydrolase
VCSRO77_0121	COG2199	diguanylate cyclase activity
VCSRO77_0121	COG2200	EAL domain
VCSRO77_0121	COG3287	FIST C domain
VCSRO77_0124	COG0561	phosphatase activity
VCSRO77_0125	COG2267	carboxylic ester hydrolase activity
VCSRO77_0126	COG1280	lysine exporter protein (LysE YggA)
VCSRO77_0127	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCSRO77_0128	COG0783	Belongs to the Dps family
VCSRO77_0133	COG0742	ribosomal rna small subunit methyltransferase
VCSRO77_0134	COG0552	protein localization to endoplasmic reticulum
VCSRO77_0135	COG2884	Cell division ATP-binding protein ftsE
VCSRO77_0136	COG2177	Part of the ABC transporter FtsEX involved in
VCSRO77_0137	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCSRO77_0138	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO77_0141	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCSRO77_0143	COG1404	Belongs to the peptidase S8 family
VCSRO77_0144	COG1404	Belongs to the peptidase S8 family
VCSRO77_0145	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
VCSRO77_0159	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VCSRO77_0161	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VCSRO77_0163	COG1072	(Pantothenic acid kinase))
VCSRO77_0168	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCSRO77_0169	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCSRO77_0170	COG0250	Participates in transcription elongation, termination and antitermination
VCSRO77_0171	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VCSRO77_0173	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VCSRO77_0174	COG0222	ribosome binding
VCSRO77_0175	COG0085	RNA polymerase activity
VCSRO77_0176	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VCSRO77_0177	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VCSRO77_0178	COG2816	NAD+ diphosphatase activity
VCSRO77_0179	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VCSRO77_0182	COG4942	peptidase
VCSRO77_0183	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VCSRO77_0185	COG0471	metal ion transport
VCSRO77_0186	COG0688	phosphatidylethanolamine metabolic process
VCSRO77_0187	COG1162	GTPase activity
VCSRO77_0188	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VCSRO77_0198	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VCSRO77_0199	COG0802	atpase or kinase
VCSRO77_0201	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VCSRO77_0202	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VCSRO77_0203	COG1923	regulation of RNA biosynthetic process
VCSRO77_0204	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VCSRO77_0205	COG0330	HflC and HflK could
VCSRO77_0206	COG0330	HflC and HflK could
VCSRO77_0207	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VCSRO77_0208	COG2900	Belongs to the SlyX family
VCSRO77_0210	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO77_0211	COG2964	Protein conserved in bacteria
VCSRO77_0212	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VCSRO77_0213	COG2923	Belongs to the DsrF TusC family
VCSRO77_0216	COG0049	tRNA binding
VCSRO77_0217	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCSRO77_0218	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCSRO77_0219	COG2906	2 iron, 2 sulfur cluster binding
VCSRO77_0221	COG0360	Binds together with S18 to 16S ribosomal RNA
VCSRO77_0222	COG2965	DNA replication, synthesis of RNA primer
VCSRO77_0223	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
VCSRO77_0224	COG0359	binds to the 23S rRNA
VCSRO77_0227	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCSRO77_0229	COG0432	Pfam Uncharacterised protein family UPF0047
VCSRO77_0238	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VCSRO77_0242	COG0432	Pfam Uncharacterised protein family UPF0047
VCSRO77_0243	COG0166	Belongs to the GPI family
VCSRO77_0246	COG0735	belongs to the Fur family
VCSRO77_0247	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO77_0251	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCSRO77_0253	COG0175	sulfate reduction
VCSRO77_0265	COG0583	DNA-binding transcription factor activity
VCSRO77_0266	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VCSRO77_0267	COG2960	long-chain fatty acid transporting porin activity
VCSRO77_0268	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO77_0269	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO77_0270	COG1309	transcriptional regulator
VCSRO77_0279	COG0747	negative chemotaxis
VCSRO77_0280	COG0601	transmembrane transport
VCSRO77_0281	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO77_0283	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO77_0284	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VCSRO77_0286	COG0210	DNA helicase
VCSRO77_0287	COG1280	lysine exporter protein (LysE YggA)
VCSRO77_0289	COG0405	Gamma-glutamyltransferase
VCSRO77_0290	COG2962	Rard protein
VCSRO77_0291	COG0514	ATP-dependent DNA helicase (RecQ)
VCSRO77_0294	COG1132	(ABC) transporter
VCSRO77_0298	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCSRO77_0299	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO77_0299	COG1263	PTS System
VCSRO77_0300	COG2862	Uncharacterized protein family, UPF0114
VCSRO77_0301	COG1561	YicC-like family, N-terminal region
VCSRO77_0302	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VCSRO77_0303	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VCSRO77_0304	COG1560	Kdo2-lipid A biosynthetic process
VCSRO77_0305	COG1560	Kdo2-lipid A biosynthetic process
VCSRO77_0306	COG1309	transcriptional regulator
VCSRO77_0307	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VCSRO77_0309	COG2003	Belongs to the UPF0758 family
VCSRO77_0310	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VCSRO77_0311	COG0267	Belongs to the bacterial ribosomal protein bL33 family
VCSRO77_0313	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VCSRO77_0314	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VCSRO77_0315	COG0859	PFAM glycosyl transferase family 9
VCSRO77_0316	COG0463	Glycosyl transferase, family 2
VCSRO77_0317	COG0859	PFAM glycosyl transferase family 9
VCSRO77_0318	COG3642	lipopolysaccharide core region biosynthetic process
VCSRO77_0319	COG2755	lipolytic protein G-D-S-L family
VCSRO77_0319	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
VCSRO77_0326	COG1519	Transferase
VCSRO77_0328	COG0859	PFAM glycosyl transferase family 9
VCSRO77_0333	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCSRO77_0334	COG0662	Cupin 2, conserved barrel domain protein
VCSRO77_0334	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
VCSRO77_0335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCSRO77_0336	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
VCSRO77_0346	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCSRO77_0347	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VCSRO77_0350	COG0668	transmembrane transport
VCSRO77_0351	COG1573	uracil-dna glycosylase
VCSRO77_0353	COG3068	Protein conserved in bacteria
VCSRO77_0355	COG1940	carbohydrate kinase activity
VCSRO77_0356	COG1253	flavin adenine dinucleotide binding
VCSRO77_0357	COG0776	regulation of translation
VCSRO77_0359	COG0151	Belongs to the GarS family
VCSRO77_0361	COG0789	Transcriptional regulator
VCSRO77_0362	COG3710	Transcriptional regulator
VCSRO77_0363	COG0531	amino acid
VCSRO77_0364	COG1982	Orn Lys Arg decarboxylase major
VCSRO77_0365	COG0840	transmembrane signaling receptor activity
VCSRO77_0368	COG0800	Aldolase
VCSRO77_0370	COG3265	gluconokinase activity
VCSRO77_0371	COG0129	dihydroxy-acid dehydratase activity
VCSRO77_0372	COG1609	Transcriptional regulator
VCSRO77_0379	COG1857	crispr-associated protein
VCSRO77_0381	COG1518	maintenance of DNA repeat elements
VCSRO77_0382	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VCSRO77_0388	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VCSRO77_0389	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO77_0391	COG0439	Biotin carboxylase
VCSRO77_0392	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO77_0393	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VCSRO77_0394	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCSRO77_0397	COG2814	Major facilitator Superfamily
VCSRO77_0398	COG2205	protein histidine kinase activity
VCSRO77_0398	COG0784	Response regulator, receiver
VCSRO77_0399	COG0248	Ppx GppA phosphatase
VCSRO77_0400	COG0513	Belongs to the DEAD box helicase family
VCSRO77_0401	COG3118	belongs to the thioredoxin family
VCSRO77_0404	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VCSRO77_0413	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VCSRO77_0414	COG3300	MHYT domain
VCSRO77_0414	COG5001	Diguanylate cyclase
VCSRO77_0416	COG3852	Histidine kinase
VCSRO77_0418	COG0174	glutamine synthetase
VCSRO77_0420	COG1217	gtp-binding protein TYPA
VCSRO77_0422	COG1295	ribonuclease BN
VCSRO77_0423	COG1490	D-aminoacyl-tRNA deacylase activity
VCSRO77_0424	COG0456	acetyltransferase
VCSRO77_0426	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
VCSRO77_0427	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VCSRO77_0428	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VCSRO77_0429	COG3031	protein transport across the cell outer membrane
VCSRO77_0431	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO77_0432	COG1459	type II secretion system
VCSRO77_0433	COG2165	general secretion pathway protein
VCSRO77_0434	COG2165	general secretion pathway protein
VCSRO77_0435	COG2165	general secretion pathway protein
VCSRO77_0436	COG4795	General secretion pathway protein
VCSRO77_0437	COG3156	type II secretion system protein K
VCSRO77_0438	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCSRO77_0439	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCSRO77_0441	COG1218	3'(2'),5'-bisphosphate nucleotidase
VCSRO77_0442	COG0494	nUDIX hydrolase
VCSRO77_0444	COG1040	competence protein
VCSRO77_0445	COG0596	Alpha beta hydrolase
VCSRO77_0447	COG2183	response to ionizing radiation
VCSRO77_0448	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO77_0449	COG2199	diguanylate cyclase activity
VCSRO77_0452	COG2233	PERMEase
VCSRO77_0453	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VCSRO77_0454	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCSRO77_0455	COG1758	RNA polymerase activity
VCSRO77_0456	COG0194	GDP metabolic process
VCSRO77_0457	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VCSRO77_0458	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCSRO77_0462	COG4232	protein-disulfide reductase activity
VCSRO77_0464	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCSRO77_0465	COG1027	Aspartate ammonia-lyase
VCSRO77_0466	COG3706	GGDEF domain
VCSRO77_0467	COG3030	protein affecting phage T7 exclusion by the F plasmid
VCSRO77_0468	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VCSRO77_0470	COG2205	protein histidine kinase activity
VCSRO77_0471	COG0745	RESPONSE REGULATOR receiver
VCSRO77_0473	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VCSRO77_0474	COG0205	6-phosphofructokinase activity
VCSRO77_0475	COG1494	fructose-1,6-bisphosphatase
VCSRO77_0476	COG3074	FtsZ-dependent cytokinesis
VCSRO77_0477	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VCSRO77_0478	COG0460	homoserine dehydrogenase
VCSRO77_0478	COG0527	aspartate kinase activity
VCSRO77_0479	COG0626	cystathionine gamma-synthase activity
VCSRO77_0480	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
VCSRO77_0481	COG0281	malic enzyme
VCSRO77_0482	COG0254	rRNA binding
VCSRO77_0483	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VCSRO77_0484	COG1609	Transcriptional regulator
VCSRO77_0485	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCSRO77_0486	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VCSRO77_0487	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VCSRO77_0488	COG1575	Belongs to the MenA family. Type 1 subfamily
VCSRO77_0489	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCSRO77_0490	COG0534	Mate efflux family protein
VCSRO77_0491	COG0149	triose-phosphate isomerase activity
VCSRO77_0496	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCSRO77_0497	COG0459	protein refolding
VCSRO77_0499	COG1509	lysine 2,3-aminomutase activity
VCSRO77_0500	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCSRO77_0502	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VCSRO77_0503	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VCSRO77_0504	COG1053	succinate dehydrogenase
VCSRO77_0505	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VCSRO77_0506	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO77_0507	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VCSRO77_0508	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VCSRO77_0509	COG1045	serine acetyltransferase
VCSRO77_0511	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VCSRO77_0512	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VCSRO77_0513	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VCSRO77_0514	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCSRO77_0515	COG0137	argininosuccinate synthase activity
VCSRO77_0516	COG0165	Argininosuccinate lyase
VCSRO77_0518	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO77_0519	COG0678	peroxiredoxin activity
VCSRO77_0519	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCSRO77_0521	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VCSRO77_0527	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VCSRO77_0528	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VCSRO77_0530	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VCSRO77_0531	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VCSRO77_0532	COG0546	phosphoglycolate phosphatase activity
VCSRO77_0533	COG0180	Tryptophanyl-tRNA synthetase
VCSRO77_0536	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCSRO77_0538	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VCSRO77_0543	COG3954	Phosphoribulokinase
VCSRO77_0545	COG0429	hydrolase of the alpha beta-hydrolase fold
VCSRO77_0547	COG0488	(ABC) transporter
VCSRO77_0548	COG2249	NAD(P)H dehydrogenase (quinone) activity
VCSRO77_0552	COG1047	Peptidyl-prolyl cis-trans
VCSRO77_0554	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VCSRO77_0555	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VCSRO77_0556	COG3083	sulfuric ester hydrolase activity
VCSRO77_0557	COG0557	exoribonuclease II activity
VCSRO77_0558	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCSRO77_0559	COG0051	transcription antitermination factor activity, RNA binding
VCSRO77_0560	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VCSRO77_0561	COG0088	Forms part of the polypeptide exit tunnel
VCSRO77_0562	COG0089	rRNA binding
VCSRO77_0563	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VCSRO77_0564	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VCSRO77_0565	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VCSRO77_0566	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VCSRO77_0567	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VCSRO77_0568	COG0255	Belongs to the universal ribosomal protein uL29 family
VCSRO77_0569	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VCSRO77_0570	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VCSRO77_0571	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VCSRO77_0572	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VCSRO77_0573	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VCSRO77_0574	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VCSRO77_0576	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VCSRO77_0577	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VCSRO77_0578	COG1841	ribosomal large subunit assembly
VCSRO77_0580	COG0201	protein transport
VCSRO77_0581	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCSRO77_0582	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VCSRO77_0583	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VCSRO77_0584	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VCSRO77_0585	COG0202	RNA polymerase activity
VCSRO77_0586	COG0203	ribosomal protein L17
VCSRO77_0588	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO77_0589	COG3266	domain, Protein
VCSRO77_0589	COG3061	Opacity-associated protein A
VCSRO77_0590	COG0697	spore germination
VCSRO77_0591	COG2153	protein acetylation
VCSRO77_0592	COG0513	Belongs to the DEAD box helicase family
VCSRO77_0594	COG0737	Belongs to the 5'-nucleotidase family
VCSRO77_0595	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VCSRO77_0595	COG1648	precorrin-2 dehydrogenase activity
VCSRO77_0596	COG0175	sulfate reduction
VCSRO77_0597	COG2895	sulfate adenylyltransferase (ATP) activity
VCSRO77_0598	COG0529	Catalyzes the synthesis of activated sulfate
VCSRO77_0602	COG1136	(ABC) transporter
VCSRO77_0602	COG0577	efflux transmembrane transporter activity
VCSRO77_0605	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VCSRO77_0606	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO77_0607	COG0729	surface antigen
VCSRO77_0609	COG2105	PFAM AIG2 family protein
VCSRO77_0610	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VCSRO77_0612	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCSRO77_0613	COG0163	prenyltransferase activity
VCSRO77_0615	COG1178	ABC-type Fe3 transport system permease component
VCSRO77_0616	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VCSRO77_0617	COG3028	Belongs to the UPF0307 family
VCSRO77_0618	COG0312	modulator of DNA gyrase
VCSRO77_0619	COG2239	Acts as a magnesium transporter
VCSRO77_0620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO77_0621	COG1660	Displays ATPase and GTPase activities
VCSRO77_0622	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO77_0623	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCSRO77_0625	COG1137	ATPase activity
VCSRO77_0626	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VCSRO77_0629	COG0517	IMP dehydrogenase activity
VCSRO77_0629	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VCSRO77_0631	COG1127	ABC transporter
VCSRO77_0632	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VCSRO77_0633	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCSRO77_0634	COG2854	intermembrane phospholipid transfer
VCSRO77_0636	COG5007	Belongs to the BolA IbaG family
VCSRO77_0637	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VCSRO77_0639	COG0251	oxidation-reduction process
VCSRO77_0641	COG0540	Belongs to the ATCase OTCase family
VCSRO77_0643	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VCSRO77_0644	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VCSRO77_0645	COG0564	pseudouridine synthase activity
VCSRO77_0646	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCSRO77_0647	COG0525	valine-tRNA ligase activity
VCSRO77_0648	COG2927	DNA polymerase III (CHI subunit)
VCSRO77_0649	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCSRO77_0650	COG0795	lipopolysaccharide-transporting ATPase activity
VCSRO77_0651	COG0795	lipopolysaccharide-transporting ATPase activity
VCSRO77_0654	COG3437	response regulator, receiver
VCSRO77_0663	COG0066	3-isopropylmalate dehydratase activity
VCSRO77_0664	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
VCSRO77_0665	COG0473	3-isopropylmalate dehydrogenase activity
VCSRO77_0670	COG0583	DNA-binding transcription factor activity
VCSRO77_0671	COG1022	Amp-dependent synthetase and ligase
VCSRO77_0672	COG0028	Belongs to the TPP enzyme family
VCSRO77_0673	COG0440	acetolactate synthase activity
VCSRO77_0674	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO77_0675	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VCSRO77_0676	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VCSRO77_0677	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VCSRO77_0678	COG3079	Belongs to the UPF0149 family
VCSRO77_0679	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO77_0680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO77_0683	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VCSRO77_0685	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VCSRO77_0686	COG1595	DNA-templated transcription, initiation
VCSRO77_0689	COG3086	response to oxidative stress
VCSRO77_0690	COG0481	GTPase activity
VCSRO77_0692	COG0571	ribonuclease III activity
VCSRO77_0693	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VCSRO77_0694	COG1381	Involved in DNA repair and RecF pathway recombination
VCSRO77_0695	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VCSRO77_0699	COG5001	Diguanylate cyclase
VCSRO77_0702	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCSRO77_0703	COG3956	TIGRFAM MazG family protein
VCSRO77_0704	COG0504	CTP synthase activity
VCSRO77_0705	COG0148	phosphopyruvate hydratase activity
VCSRO77_0707	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO77_0707	COG3267	Type II secretory pathway component ExeA
VCSRO77_0709	COG4991	sh3 domain protein
VCSRO77_0710	COG0306	phosphate transporter
VCSRO77_0711	COG1392	Phosphate transport regulator
VCSRO77_0712	COG3025	triphosphatase activity
VCSRO77_0715	COG0840	transmembrane signaling receptor activity
VCSRO77_0716	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VCSRO77_0718	COG1538	Outer membrane efflux protein
VCSRO77_0719	COG0494	nUDIX hydrolase
VCSRO77_0720	COG3151	Protein conserved in bacteria
VCSRO77_0722	COG3150	esterase
VCSRO77_0723	COG0187	DNA topoisomerase II activity
VCSRO77_0724	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VCSRO77_0726	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VCSRO77_0727	COG0237	dephospho-CoA kinase activity
VCSRO77_0729	COG1459	type II secretion system
VCSRO77_0730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO77_0731	COG4969	Belongs to the N-Me-Phe pilin family
VCSRO77_0734	COG0716	FMN binding
VCSRO77_0735	COG4974	Belongs to the 'phage' integrase family
VCSRO77_0736	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCSRO77_0737	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VCSRO77_0738	COG0737	Belongs to the 5'-nucleotidase family
VCSRO77_0739	COG2186	Transcriptional regulator
VCSRO77_0740	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VCSRO77_0741	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCSRO77_0742	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO77_0744	COG3116	cell division
VCSRO77_0745	COG0768	penicillin binding
VCSRO77_0746	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VCSRO77_0747	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VCSRO77_0749	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VCSRO77_0750	COG0772	Belongs to the SEDS family
VCSRO77_0751	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
VCSRO77_0752	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCSRO77_0753	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VCSRO77_0754	COG0849	cell division
VCSRO77_0755	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VCSRO77_0756	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VCSRO77_0758	COG0653	protein targeting
VCSRO77_0759	COG0494	nUDIX hydrolase
VCSRO77_0760	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
VCSRO77_0761	COG0505	Belongs to the CarA family
VCSRO77_0762	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VCSRO77_0765	COG0730	response to heat
VCSRO77_0766	COG0583	DNA-binding transcription factor activity
VCSRO77_0767	COG2860	membrane
VCSRO77_0768	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VCSRO77_0770	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VCSRO77_0772	COG0493	'glutamate synthase
VCSRO77_0773	COG0067	glutamate synthase
VCSRO77_0773	COG0069	glutamate synthase activity
VCSRO77_0773	COG0070	glutamate synthase
VCSRO77_0775	COG0067	glutamate synthase
VCSRO77_0775	COG0069	glutamate synthase activity
VCSRO77_0775	COG0070	glutamate synthase
VCSRO77_0776	COG1242	4 iron, 4 sulfur cluster binding
VCSRO77_0777	COG5001	Diguanylate cyclase
VCSRO77_0777	COG4251	negative regulation of phosphorylation
VCSRO77_0777	COG2203	Gaf domain
VCSRO77_0777	COG3706	GGDEF domain
VCSRO77_0778	COG2198	Histidine kinase
VCSRO77_0778	COG5002	protein histidine kinase activity
VCSRO77_0778	COG0784	Response regulator, receiver
VCSRO77_0779	COG0745	RESPONSE REGULATOR receiver
VCSRO77_0781	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCSRO77_0784	COG0083	homoserine kinase activity
VCSRO77_0785	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VCSRO77_0786	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VCSRO77_0787	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VCSRO77_0788	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VCSRO77_0791	COG1115	amino acid carrier protein
VCSRO77_0792	COG3022	response to hydroperoxide
VCSRO77_0794	COG0084	hydrolase, TatD family'
VCSRO77_0795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO77_0796	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VCSRO77_0797	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO77_0798	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VCSRO77_0799	COG0813	purine-nucleoside phosphorylase activity
VCSRO77_0801	COG0560	Phosphoserine phosphatase
VCSRO77_0803	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VCSRO77_0804	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCSRO77_0805	COG1022	Amp-dependent synthetase and ligase
VCSRO77_0808	COG3250	beta-galactosidase activity
VCSRO77_0809	COG1609	Transcriptional regulator
VCSRO77_0810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO77_0813	COG0189	ligase activity
VCSRO77_0813	COG0569	domain protein
VCSRO77_0817	COG2171	N-acyltransferase activity
VCSRO77_0818	COG3141	response to X-ray
VCSRO77_0821	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VCSRO77_0822	COG1074	ATP-dependent DNA helicase activity
VCSRO77_0823	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VCSRO77_0825	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCSRO77_0825	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VCSRO77_0827	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VCSRO77_0828	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VCSRO77_0829	COG2166	iron-sulfur cluster assembly
VCSRO77_0830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCSRO77_0831	COG0693	protein deglycase activity
VCSRO77_0832	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VCSRO77_0835	COG1595	DNA-templated transcription, initiation
VCSRO77_0837	COG2211	Major facilitator Superfamily
VCSRO77_0838	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCSRO77_0840	COG2813	Specifically methylates the guanine in position
VCSRO77_0841	COG0271	Belongs to the BolA IbaG family
VCSRO77_0842	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO77_0843	COG1805	sodium ion transport
VCSRO77_0844	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO77_0845	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO77_0846	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO77_0847	COG2871	sodium ion transport
VCSRO77_0848	COG1477	protein flavinylation
VCSRO77_0852	COG3706	GGDEF domain
VCSRO77_0853	COG0733	neurotransmitter:sodium symporter activity
VCSRO77_0855	COG0189	ligase activity
VCSRO77_0856	COG4067	protein conserved in archaea
VCSRO77_0856	COG0189	ligase activity
VCSRO77_0857	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO77_0858	COG2252	PERMEase
VCSRO77_0859	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VCSRO77_0860	COG1073	alpha beta
VCSRO77_0862	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VCSRO77_0863	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VCSRO77_0864	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VCSRO77_0865	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO77_0865	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO77_0868	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VCSRO77_0869	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCSRO77_0870	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VCSRO77_0871	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VCSRO77_0873	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VCSRO77_0874	COG0024	Methionine aminopeptidase
VCSRO77_0875	COG0052	Belongs to the universal ribosomal protein uS2 family
VCSRO77_0876	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VCSRO77_0877	COG0528	UMP kinase activity
VCSRO77_0878	COG0233	cytoplasmic translational termination
VCSRO77_0879	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VCSRO77_0880	COG0575	Belongs to the CDS family
VCSRO77_0881	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VCSRO77_0882	COG0750	zinc metalloprotease
VCSRO77_0884	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VCSRO77_0885	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO77_0886	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCSRO77_0887	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO77_0888	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO77_0889	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
VCSRO77_0890	COG0587	DNA-directed DNA polymerase activity
VCSRO77_0891	COG0825	malonyl-CoA metabolic process
VCSRO77_0892	COG0037	tRNA processing
VCSRO77_0894	COG3479	Phenolic acid decarboxylase
VCSRO77_0895	COG0347	Belongs to the P(II) protein family
VCSRO77_0896	COG3021	interspecies interaction between organisms
VCSRO77_0897	COG0741	lytic transglycosylase activity
VCSRO77_0897	COG1388	LysM domain
VCSRO77_0898	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCSRO77_0899	COG2226	methyltransferase
VCSRO77_0900	COG0328	RNA-DNA hybrid ribonuclease activity
VCSRO77_0903	COG1960	acyl-CoA dehydrogenase activity
VCSRO77_0904	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCSRO77_0905	COG0121	glutamine amidotransferase
VCSRO77_0906	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VCSRO77_0907	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VCSRO77_0908	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VCSRO77_0910	COG1187	pseudouridine synthase activity
VCSRO77_0911	COG2840	Smr protein MutS2
VCSRO77_0914	COG3735	TraB family
VCSRO77_0917	COG2217	Heavy metal translocating P-type atpase
VCSRO77_0917	COG2608	mercury ion transmembrane transporter activity
VCSRO77_0918	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCSRO77_0921	COG4774	siderophore transport
VCSRO77_0921	COG1629	transport
VCSRO77_0922	COG2375	cellular response to nickel ion
VCSRO77_0923	COG2226	methyltransferase
VCSRO77_0923	COG3433	isochorismatase activity
VCSRO77_0923	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCSRO77_0930	COG0784	Response regulator, receiver
VCSRO77_0930	COG0835	chemotaxis
VCSRO77_0931	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCSRO77_0932	COG1815	bacterial-type flagellum-dependent cell motility
VCSRO77_0935	COG1749	Flagellar hook protein flgE
VCSRO77_0936	COG4787	bacterial-type flagellum-dependent cell motility
VCSRO77_0938	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VCSRO77_0939	COG1706	bacterial-type flagellum-dependent cell motility
VCSRO77_0940	COG1705	Flagellar rod assembly protein muramidase FlgJ
VCSRO77_0940	COG3951	Flagellar rod assembly protein muramidase FlgJ
VCSRO77_0943	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO77_0944	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO77_0961	COG0012	GTP binding
VCSRO77_0962	COG0193	aminoacyl-tRNA hydrolase activity
VCSRO77_0963	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VCSRO77_0964	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VCSRO77_0965	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VCSRO77_0966	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VCSRO77_0967	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VCSRO77_0968	COG2890	protein-(glutamine-N5) methyltransferase activity
VCSRO77_0970	COG2912	Transglutaminase-like superfamily
VCSRO77_0971	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VCSRO77_0972	COG0737	Belongs to the 5'-nucleotidase family
VCSRO77_0973	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VCSRO77_0974	COG2233	PERMEase
VCSRO77_0978	COG1393	Belongs to the ArsC family
VCSRO77_0979	COG4783	chaperone-mediated protein folding
VCSRO77_0983	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VCSRO77_0986	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VCSRO77_0988	COG1876	peptidase activity
VCSRO77_0990	COG1393	Belongs to the ArsC family
VCSRO77_0994	COG2837	iron assimilation
VCSRO77_0995	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO77_0996	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO77_0997	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO77_0998	COG1334	flagellar protein FlaG
VCSRO77_0999	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VCSRO77_1001	COG1516	flagellar protein fliS
VCSRO77_1006	COG1677	Flagellar hook-basal body complex protein FliE
VCSRO77_1008	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VCSRO77_1009	COG1317	bacterial-type flagellum organization
VCSRO77_1013	COG1580	Controls the rotational direction of flagella during chemotaxis
VCSRO77_1018	COG1987	bacterial-type flagellum assembly
VCSRO77_1019	COG1684	flagellar biosynthetic protein fliR
VCSRO77_1021	COG2840	Smr protein MutS2
VCSRO77_1022	COG2890	protein-(glutamine-N5) methyltransferase activity
VCSRO77_1023	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VCSRO77_1024	COG2860	membrane
VCSRO77_1025	COG3101	peptidyl-lysine hydroxylation
VCSRO77_1027	COG0431	NADPH-dependent FMN reductase
VCSRO77_1028	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VCSRO77_1028	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VCSRO77_1029	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCSRO77_1030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO77_1031	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCSRO77_1032	COG0735	belongs to the Fur family
VCSRO77_1034	COG0583	DNA-binding transcription factor activity
VCSRO77_1036	COG1346	cytolysis
VCSRO77_1039	COG0596	Alpha beta hydrolase
VCSRO77_1040	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VCSRO77_1041	COG0033	Phosphoglucomutase
VCSRO77_1043	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VCSRO77_1044	COG0372	Belongs to the citrate synthase family
VCSRO77_1045	COG2009	succinate dehydrogenase
VCSRO77_1046	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VCSRO77_1047	COG1053	succinate dehydrogenase
VCSRO77_1049	COG0567	Dehydrogenase, E1 component
VCSRO77_1050	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCSRO77_1051	COG0045	succinate-CoA ligase (ADP-forming) activity
VCSRO77_1053	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VCSRO77_1054	COG1121	(ABC) transporter
VCSRO77_1055	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VCSRO77_1056	COG4977	sequence-specific DNA binding
VCSRO77_1057	COG1918	ferrous iron import across plasma membrane
VCSRO77_1061	COG0018	arginyl-trna synthetase
VCSRO77_1063	COG1025	Belongs to the peptidase M16 family
VCSRO77_1064	COG2062	phosphohistidine phosphatase, SixA
VCSRO77_1070	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VCSRO77_1071	COG0643	Histidine kinase
VCSRO77_1071	COG0784	Response regulator, receiver
VCSRO77_1071	COG2198	Histidine kinase
VCSRO77_1072	COG2201	protein-glutamate methylesterase activity
VCSRO77_1073	COG1192	Involved in chromosome partitioning
VCSRO77_1075	COG0835	chemotaxis
VCSRO77_1077	COG4133	protoheme IX ABC transporter activity
VCSRO77_1078	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCSRO77_1079	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCSRO77_1081	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VCSRO77_1082	COG1138	Cytochrome C-type biogenesis protein
VCSRO77_1083	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VCSRO77_1084	COG3088	subunit of a heme lyase
VCSRO77_1084	COG4235	cytochrome complex assembly
VCSRO77_1086	COG2853	Lipoprotein
VCSRO77_1090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VCSRO77_1091	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCSRO77_1092	COG0123	including yeast histone deacetylase and acetoin utilization protein
VCSRO77_1095	COG3083	sulfuric ester hydrolase activity
VCSRO77_1096	COG3082	Protein of unknown function (DUF1414)
VCSRO77_1097	COG3081	Nucleoid-associated protein
VCSRO77_1099	COG1757	Na H antiporter
VCSRO77_1100	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCSRO77_1101	COG2095	MarC family integral membrane protein
VCSRO77_1102	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO77_1102	COG1454	alcohol dehydrogenase
VCSRO77_1105	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO77_1106	COG1530	ribonuclease E activity
VCSRO77_1107	COG0564	pseudouridine synthase activity
VCSRO77_1108	COG0424	maF-like protein
VCSRO77_1109	COG1399	metal-binding, possibly nucleic acid-binding protein
VCSRO77_1110	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VCSRO77_1111	COG0416	fatty acid biosynthetic process
VCSRO77_1112	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCSRO77_1114	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO77_1115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VCSRO77_1116	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCSRO77_1117	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCSRO77_1118	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VCSRO77_1119	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VCSRO77_1121	COG0084	hydrolase, TatD family'
VCSRO77_1122	COG1263	PTS System
VCSRO77_1122	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO77_1124	COG0733	neurotransmitter:sodium symporter activity
VCSRO77_1126	COG0733	neurotransmitter:sodium symporter activity
VCSRO77_1129	COG4667	esterase of the alpha-beta hydrolase superfamily
VCSRO77_1131	COG1940	carbohydrate kinase activity
VCSRO77_1132	COG0784	Response regulator, receiver
VCSRO77_1132	COG0835	chemotaxis
VCSRO77_1135	COG2226	methyltransferase
VCSRO77_1137	COG0676	glucose-6-phosphate 1-epimerase activity
VCSRO77_1138	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO77_1139	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO77_1141	COG3139	Protein of unknown function (DUF1315)
VCSRO77_1142	COG0252	asparaginase activity
VCSRO77_1143	COG0616	signal peptide processing
VCSRO77_1144	COG1902	pentaerythritol trinitrate reductase activity
VCSRO77_1144	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCSRO77_1145	COG0788	formyltetrahydrofolate deformylase activity
VCSRO77_1147	COG1199	ATP-dependent helicase activity
VCSRO77_1148	COG1214	PFAM Peptidase M22, glycoprotease
VCSRO77_1151	COG0596	Alpha beta hydrolase
VCSRO77_1152	COG0318	PFAM AMP-dependent synthetase and ligase
VCSRO77_1153	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VCSRO77_1156	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VCSRO77_1157	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VCSRO77_1158	COG0436	Aminotransferase
VCSRO77_1159	COG1169	isochorismate synthase
VCSRO77_1160	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VCSRO77_1161	COG0596	Alpha beta hydrolase
VCSRO77_1165	COG3135	benzoate transporter
VCSRO77_1166	COG1396	sequence-specific DNA binding
VCSRO77_1167	COG0840	transmembrane signaling receptor activity
VCSRO77_1173	COG3015	lipoprotein NlpE involved in copper resistance
VCSRO77_1174	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VCSRO77_1175	COG2894	cell division
VCSRO77_1176	COG0850	regulation of cytokinetic process
VCSRO77_1177	COG3100	YcgL domain-containing protein
VCSRO77_1178	COG2951	lytic endotransglycosylase activity
VCSRO77_1181	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO77_1182	COG3469	chitinase activity
VCSRO77_1182	COG3325	Belongs to the glycosyl hydrolase 18 family
VCSRO77_1183	COG3005	denitrification pathway
VCSRO77_1184	COG0243	molybdopterin cofactor binding
VCSRO77_1188	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO77_1190	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VCSRO77_1197	COG4589	Belongs to the CDS family
VCSRO77_1199	COG3300	MHYT domain
VCSRO77_1199	COG5001	Diguanylate cyclase
VCSRO77_1202	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VCSRO77_1203	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCSRO77_1204	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCSRO77_1205	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCSRO77_1207	COG4191	Histidine kinase
VCSRO77_1208	COG0544	peptidyl-prolyl cis-trans isomerase activity
VCSRO77_1210	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VCSRO77_1211	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VCSRO77_1212	COG0776	regulation of translation
VCSRO77_1213	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO77_1214	COG1555	photosystem II stabilization
VCSRO77_1215	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VCSRO77_1216	COG0539	negative regulation of cytoplasmic translation
VCSRO77_1217	COG0776	regulation of translation
VCSRO77_1218	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VCSRO77_1219	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VCSRO77_1223	COG0583	DNA-binding transcription factor activity
VCSRO77_1225	COG0686	Belongs to the AlaDH PNT family
VCSRO77_1227	COG1674	ftsk spoiiie
VCSRO77_1228	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VCSRO77_1229	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCSRO77_1230	COG2186	Transcriptional regulator
VCSRO77_1233	COG0537	adenosine 5'-monophosphoramidase activity
VCSRO77_1238	COG3150	esterase
VCSRO77_1239	COG1252	NADH dehydrogenase
VCSRO77_1243	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VCSRO77_1245	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO77_1246	COG1136	(ABC) transporter
VCSRO77_1247	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO77_1249	COG0658	competence protein
VCSRO77_1249	COG2333	competence protein COMEC
VCSRO77_1250	COG1132	(ABC) transporter
VCSRO77_1251	COG1663	tetraacyldisaccharide 4'-kinase activity
VCSRO77_1252	COG2835	tetraacyldisaccharide 4'-kinase activity
VCSRO77_1253	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VCSRO77_1254	COG2719	SpoVR family
VCSRO77_1255	COG2718	Belongs to the UPF0229 family
VCSRO77_1256	COG2766	serine protein kinase
VCSRO77_1258	COG2766	serine protein kinase
VCSRO77_1259	COG3013	Belongs to the UPF0304 family
VCSRO77_1261	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VCSRO77_1262	COG0840	transmembrane signaling receptor activity
VCSRO77_1264	COG1882	Formate acetyltransferase
VCSRO77_1270	COG4160	amino acid transport
VCSRO77_1271	COG0708	Exodeoxyribonuclease III
VCSRO77_1272	COG0840	transmembrane signaling receptor activity
VCSRO77_1274	COG3923	Primosomal replication protein n
VCSRO77_1275	COG0730	response to heat
VCSRO77_1276	COG1199	ATP-dependent helicase activity
VCSRO77_1277	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCSRO77_1279	COG3012	SEC-C Motif Domain Protein
VCSRO77_1280	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCSRO77_1281	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO77_1282	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCSRO77_1283	COG0215	cysteine-tRNA ligase activity
VCSRO77_1284	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VCSRO77_1285	COG0632	four-way junction helicase activity
VCSRO77_1288	COG1271	oxidase subunit
VCSRO77_1289	COG1294	oxidase, subunit
VCSRO77_1290	COG4890	Cyd operon protein YbgT
VCSRO77_1291	COG3790	cyd operon protein YbgE
VCSRO77_1292	COG0824	Thioesterase
VCSRO77_1293	COG0811	peptide transport
VCSRO77_1296	COG0823	Involved in the tonB-independent uptake of proteins
VCSRO77_1297	COG2885	chlorophyll binding
VCSRO77_1299	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VCSRO77_1301	COG0784	Response regulator, receiver
VCSRO77_1301	COG5002	protein histidine kinase activity
VCSRO77_1303	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO77_1304	COG3284	Transcriptional regulator
VCSRO77_1305	COG4628	conserved protein (DUF2132)
VCSRO77_1307	COG0415	Belongs to the DNA photolyase family
VCSRO77_1311	COG4409	exo-alpha-(2->6)-sialidase activity
VCSRO77_1312	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VCSRO77_1313	COG1940	carbohydrate kinase activity
VCSRO77_1315	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCSRO77_1316	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCSRO77_1317	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCSRO77_1318	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VCSRO77_1319	COG1737	Transcriptional regulator
VCSRO77_1320	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VCSRO77_1321	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VCSRO77_1327	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VCSRO77_1328	COG4804	nuclease activity
VCSRO77_1329	COG0732	type I restriction modification DNA specificity domain
VCSRO77_1332	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VCSRO77_1333	COG0582	viral genome integration into host DNA
VCSRO77_1334	COG0582	viral genome integration into host DNA
VCSRO77_1346	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VCSRO77_1348	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VCSRO77_1354	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
VCSRO77_1363	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCSRO77_1366	COG0681	Belongs to the peptidase S26 family
VCSRO77_1377	COG3064	Membrane
VCSRO77_1385	COG4932	domain protein
VCSRO77_1385	COG5492	domain, Protein
VCSRO77_1387	COG2165	general secretion pathway protein
VCSRO77_1390	COG4796	Type ii and iii secretion system protein
VCSRO77_1394	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO77_1395	COG1459	type II secretion system
VCSRO77_1399	COG2207	Transcriptional regulator
VCSRO77_1408	COG3710	Transcriptional regulator
VCSRO77_1409	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO77_1419	COG0629	single-stranded DNA binding
VCSRO77_1423	COG0714	Associated with various cellular activities
VCSRO77_1428	COG2003	Belongs to the UPF0758 family
VCSRO77_1436	COG2801	Transposase and inactivated derivatives
VCSRO77_1437	COG3311	Transcriptional regulator
VCSRO77_1438	COG0582	viral genome integration into host DNA
VCSRO77_1441	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO77_1443	COG3008	intermembrane lipid transfer
VCSRO77_1443	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCSRO77_1444	COG2995	paraquat-inducible protein a
VCSRO77_1445	COG1309	transcriptional regulator
VCSRO77_1446	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO77_1450	COG1960	acyl-CoA dehydrogenase activity
VCSRO77_1451	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCSRO77_1452	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VCSRO77_1453	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
VCSRO77_1454	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VCSRO77_1457	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCSRO77_1458	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCSRO77_1459	COG0297	glycogen (starch) synthase activity
VCSRO77_1463	COG3070	regulator of competence-specific genes
VCSRO77_1464	COG1609	Transcriptional regulator
VCSRO77_1466	COG0745	RESPONSE REGULATOR receiver
VCSRO77_1467	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCSRO77_1468	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCSRO77_1469	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VCSRO77_1470	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VCSRO77_1471	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
VCSRO77_1474	COG1032	radical SAM domain protein
VCSRO77_1476	COG0612	Peptidase, M16
VCSRO77_1479	COG0583	DNA-binding transcription factor activity
VCSRO77_1480	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VCSRO77_1482	COG2350	Protein conserved in bacteria
VCSRO77_1483	COG1607	acyl-coa hydrolase
VCSRO77_1486	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCSRO77_1487	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCSRO77_1489	COG2116	formate transmembrane transporter activity
VCSRO77_1490	COG4459	periplasmic nitrate reductase
VCSRO77_1491	COG3005	denitrification pathway
VCSRO77_1492	COG0243	molybdopterin cofactor binding
VCSRO77_1495	COG1227	inorganic diphosphatase activity
VCSRO77_1498	COG4172	Belongs to the ABC transporter superfamily
VCSRO77_1501	COG4168	peptide transport system, permease
VCSRO77_1503	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VCSRO77_1504	COG1842	Phage shock protein A
VCSRO77_1507	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO77_1510	COG2818	Glycosylase
VCSRO77_1511	COG0626	cystathionine gamma-synthase activity
VCSRO77_1513	COG0733	neurotransmitter:sodium symporter activity
VCSRO77_1514	COG0564	pseudouridine synthase activity
VCSRO77_1515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VCSRO77_1516	COG4136	ATPase activity
VCSRO77_1517	COG4135	transport system, permease component
VCSRO77_1518	COG4134	Bacterial extracellular solute-binding protein
VCSRO77_1520	COG3313	Fe-S protein
VCSRO77_1522	COG0842	Transport permease protein
VCSRO77_1523	COG1131	(ABC) transporter
VCSRO77_1524	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO77_1525	COG0814	amino acid
VCSRO77_1527	COG2239	Acts as a magnesium transporter
VCSRO77_1530	COG0784	Response regulator, receiver
VCSRO77_1530	COG2205	protein histidine kinase activity
VCSRO77_1533	COG4934	collagen metabolic process
VCSRO77_1539	COG0840	transmembrane signaling receptor activity
VCSRO77_1541	COG5001	Diguanylate cyclase
VCSRO77_1541	COG4251	negative regulation of phosphorylation
VCSRO77_1541	COG3706	GGDEF domain
VCSRO77_1541	COG2203	Gaf domain
VCSRO77_1542	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VCSRO77_1546	COG1061	Type III restriction enzyme res subunit
VCSRO77_1547	COG1187	pseudouridine synthase activity
VCSRO77_1548	COG2814	Major facilitator Superfamily
VCSRO77_1550	COG0702	epimerase
VCSRO77_1551	COG0534	Mate efflux family protein
VCSRO77_1552	COG4181	ATPase activity
VCSRO77_1553	COG0577	efflux transmembrane transporter activity
VCSRO77_1555	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCSRO77_1557	COG1748	Saccharopine dehydrogenase
VCSRO77_1560	COG1538	Outer membrane efflux protein
VCSRO77_1562	COG3385	transposase activity
VCSRO77_1565	COG0583	DNA-binding transcription factor activity
VCSRO77_1567	COG1451	nucleotide metabolic process
VCSRO77_1570	COG3063	Type IV pilus biogenesis stability protein PilW
VCSRO77_1571	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VCSRO77_1575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO77_1578	COG3290	protein histidine kinase activity
VCSRO77_1579	COG4565	transcriptional regulatory protein
VCSRO77_1581	COG0835	chemotaxis
VCSRO77_1581	COG0784	Response regulator, receiver
VCSRO77_1589	COG1085	galactose-1-phosphate uridylyltransferase
VCSRO77_1590	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VCSRO77_1591	COG2017	converts alpha-aldose to the beta-anomer
VCSRO77_1594	COG3527	Alpha-acetolactate decarboxylase
VCSRO77_1597	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCSRO77_1599	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCSRO77_1602	COG3097	Belongs to the UPF0267 family
VCSRO77_1607	COG1271	oxidase subunit
VCSRO77_1608	COG1294	oxidase, subunit
VCSRO77_1609	COG1136	(ABC) transporter
VCSRO77_1609	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO77_1610	COG0577	efflux transmembrane transporter activity
VCSRO77_1610	COG1136	(ABC) transporter
VCSRO77_1611	COG0577	efflux transmembrane transporter activity
VCSRO77_1611	COG1136	(ABC) transporter
VCSRO77_1617	COG2723	6-phospho-beta-galactosidase activity
VCSRO77_1618	COG1609	Transcriptional regulator
VCSRO77_1619	COG0251	oxidation-reduction process
VCSRO77_1620	COG2731	YhcH YjgK YiaL family protein
VCSRO77_1621	COG0584	glycerophosphoryl diester phosphodiesterase
VCSRO77_1622	COG1349	DNA-binding transcription factor activity
VCSRO77_1623	COG3842	ATPase activity
VCSRO77_1624	COG0395	ABC-type sugar transport system, permease component
VCSRO77_1625	COG1175	transmembrane transport
VCSRO77_1628	COG0811	peptide transport
VCSRO77_1629	COG0811	peptide transport
VCSRO77_1630	COG0848	biopolymer transport protein
VCSRO77_1631	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCSRO77_1634	COG0534	Mate efflux family protein
VCSRO77_1636	COG3001	Fructosamine kinase
VCSRO77_1638	COG0791	NLP P60 protein
VCSRO77_1639	COG0840	transmembrane signaling receptor activity
VCSRO77_1641	COG3148	PFAM DTW domain containing protein
VCSRO77_1642	COG1940	carbohydrate kinase activity
VCSRO77_1645	COG0746	molybdenum cofactor guanylyltransferase activity
VCSRO77_1646	COG3842	ATPase activity
VCSRO77_1647	COG4662	Binding-protein-dependent transport system inner membrane component
VCSRO77_1649	COG2204	response regulator
VCSRO77_1650	COG3852	Histidine kinase
VCSRO77_1651	COG0488	(ABC) transporter
VCSRO77_1652	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VCSRO77_1658	COG0243	molybdopterin cofactor binding
VCSRO77_1658	COG3383	formate dehydrogenase (NAD+) activity
VCSRO77_1659	COG0437	4 iron, 4 sulfur cluster binding
VCSRO77_1662	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VCSRO77_1663	COG1666	GTP binding
VCSRO77_1664	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO77_1667	COG2996	Protein conserved in bacteria
VCSRO77_1669	COG3008	intermembrane lipid transfer
VCSRO77_1670	COG2995	paraquat-inducible protein a
VCSRO77_1671	COG1132	(ABC) transporter
VCSRO77_1672	COG1956	GAF domain-containing protein
VCSRO77_1673	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VCSRO77_1677	COG0308	aminopeptidase N
VCSRO77_1680	COG0167	dihydroorotate dehydrogenase activity
VCSRO77_1683	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCSRO77_1683	COG0116	Belongs to the methyltransferase superfamily
VCSRO77_1685	COG0488	(ABC) transporter
VCSRO77_1688	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCSRO77_1689	COG1067	ATP-dependent peptidase activity
VCSRO77_1690	COG3120	sequence-specific DNA binding
VCSRO77_1693	COG1073	alpha beta
VCSRO77_1693	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VCSRO77_1693	COG3064	Membrane
VCSRO77_1694	COG2994	toxin metabolic process
VCSRO77_1699	COG0784	Response regulator, receiver
VCSRO77_1699	COG2205	protein histidine kinase activity
VCSRO77_1702	COG3278	Belongs to the heme-copper respiratory oxidase family
VCSRO77_1705	COG2010	Cytochrome c
VCSRO77_1707	COG2217	Heavy metal translocating P-type atpase
VCSRO77_1710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VCSRO77_1711	COG0589	response to stress
VCSRO77_1712	COG0037	tRNA processing
VCSRO77_1716	COG3842	ATPase activity
VCSRO77_1718	COG1177	transmembrane transport
VCSRO77_1720	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCSRO77_1723	COG1115	amino acid carrier protein
VCSRO77_1724	COG1280	lysine exporter protein (LysE YggA)
VCSRO77_1728	COG3501	Rhs element vgr protein
VCSRO77_1730	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VCSRO77_1731	COG0840	transmembrane signaling receptor activity
VCSRO77_1732	COG2814	Major facilitator Superfamily
VCSRO77_1733	COG1566	PFAM secretion protein HlyD family protein
VCSRO77_1734	COG1538	Outer membrane efflux protein
VCSRO77_1736	COG0513	Belongs to the DEAD box helicase family
VCSRO77_1738	COG0840	transmembrane signaling receptor activity
VCSRO77_1740	COG0415	Belongs to the DNA photolyase family
VCSRO77_1741	COG0477	Major facilitator Superfamily
VCSRO77_1742	COG0583	DNA-binding transcription factor activity
VCSRO77_1743	COG0095	Lipoate-protein ligase
VCSRO77_1744	COG0443	Heat shock 70 kDa protein
VCSRO77_1746	COG1643	Atp-dependent helicase
VCSRO77_1753	COG0443	Heat shock 70 kDa protein
VCSRO77_1754	COG0443	Heat shock 70 kDa protein
VCSRO77_1755	COG3706	GGDEF domain
VCSRO77_1761	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VCSRO77_1762	COG0602	queuosine metabolic process
VCSRO77_1764	COG0561	phosphatase activity
VCSRO77_1766	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO77_1767	COG4597	amino acid ABC transporter
VCSRO77_1768	COG0765	amino acid transport
VCSRO77_1769	COG1126	abc transporter atp-binding protein
VCSRO77_1770	COG0670	Belongs to the BI1 family
VCSRO77_1771	COG2920	part of a sulfur-relay system
VCSRO77_1772	COG1254	Belongs to the acylphosphatase family
VCSRO77_1773	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCSRO77_1774	COG3706	GGDEF domain
VCSRO77_1776	COG2205	protein histidine kinase activity
VCSRO77_1776	COG3437	response regulator, receiver
VCSRO77_1776	COG3850	Histidine kinase
VCSRO77_1776	COG4999	Histidine kinase
VCSRO77_1777	COG3437	response regulator, receiver
VCSRO77_1778	COG0625	glutathione transferase activity
VCSRO77_1780	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VCSRO77_1782	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO77_1788	COG0372	Belongs to the citrate synthase family
VCSRO77_1789	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VCSRO77_1797	COG1566	PFAM secretion protein HlyD family protein
VCSRO77_1801	COG1129	ABC transporter
VCSRO77_1806	COG0745	RESPONSE REGULATOR receiver
VCSRO77_1807	COG5002	protein histidine kinase activity
VCSRO77_1808	COG3713	MltA-interacting MipA family protein
VCSRO77_1809	COG2990	Protein conserved in bacteria
VCSRO77_1811	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO77_1811	COG4191	Histidine kinase
VCSRO77_1812	COG0471	metal ion transport
VCSRO77_1814	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCSRO77_1817	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO77_1819	COG3768	UPF0283 membrane protein
VCSRO77_1820	COG3106	COG3106 Predicted ATPase
VCSRO77_1823	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCSRO77_1824	COG0494	nUDIX hydrolase
VCSRO77_1825	COG0814	amino acid
VCSRO77_1826	COG1760	l-serine dehydratase
VCSRO77_1827	COG0720	synthase
VCSRO77_1828	COG0840	transmembrane signaling receptor activity
VCSRO77_1829	COG0017	Asparaginyl-tRNA synthetase
VCSRO77_1830	COG0351	phosphomethylpyrimidine kinase
VCSRO77_1831	COG2770	Histidine kinase
VCSRO77_1831	COG3437	response regulator, receiver
VCSRO77_1832	COG1448	Aminotransferase
VCSRO77_1836	COG0840	transmembrane signaling receptor activity
VCSRO77_1837	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
VCSRO77_1838	COG2943	transferase activity, transferring hexosyl groups
VCSRO77_1839	COG1609	Transcriptional regulator
VCSRO77_1840	COG3394	polysaccharide catabolic process
VCSRO77_1841	COG1486	melibiose metabolic process
VCSRO77_1842	COG1447	Phosphotransferase system cellobiose-specific component IIA
VCSRO77_1845	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VCSRO77_1846	COG0726	polysaccharide deacetylase
VCSRO77_1847	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VCSRO77_1848	COG1846	Transcriptional regulator
VCSRO77_1853	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCSRO77_1856	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCSRO77_1857	COG3108	Peptidase M15
VCSRO77_1863	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VCSRO77_1865	COG2814	Major facilitator Superfamily
VCSRO77_1867	COG1054	Belongs to the UPF0176 family
VCSRO77_1868	COG1054	Belongs to the UPF0176 family
VCSRO77_1870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCSRO77_1871	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCSRO77_1872	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCSRO77_1881	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
VCSRO77_1882	COG4139	cobalamin transport
VCSRO77_1883	COG2988	succinylglutamate desuccinylase activity
VCSRO77_1886	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VCSRO77_1887	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VCSRO77_1888	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO77_1889	COG1823	symporter activity
VCSRO77_1890	COG2925	Exonuclease
VCSRO77_1891	COG1380	Effector of murein hydrolase LrgA
VCSRO77_1892	COG1346	cytolysis
VCSRO77_1899	COG0776	regulation of translation
VCSRO77_1900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO77_1900	COG0072	phenylalanine-tRNA ligase activity
VCSRO77_1901	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VCSRO77_1909	COG0322	excinuclease ABC activity
VCSRO77_1910	COG2197	response regulator
VCSRO77_1911	COG0417	DNA replication proofreading
VCSRO77_1912	COG5001	Diguanylate cyclase
VCSRO77_1914	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCSRO77_1915	COG3099	Belongs to the UPF0263 family
VCSRO77_1918	COG1228	amidohydrolase
VCSRO77_1919	COG0010	Belongs to the arginase family
VCSRO77_1920	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VCSRO77_1921	COG2986	histidine ammonia-lyase
VCSRO77_1923	COG3385	transposase activity
VCSRO77_1926	COG0277	FAD linked oxidase domain protein
VCSRO77_1926	COG0247	lactate metabolic process
VCSRO77_1929	COG2885	chlorophyll binding
VCSRO77_1933	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VCSRO77_1935	COG0281	malic enzyme
VCSRO77_1937	COG2949	membrane
VCSRO77_1938	COG3706	GGDEF domain
VCSRO77_1941	COG0492	ferredoxin-NADP+ reductase activity
VCSRO77_1942	COG4988	ABC transporter
VCSRO77_1943	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VCSRO77_1944	COG1187	pseudouridine synthase activity
VCSRO77_1945	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO77_1946	COG0613	PHP domain protein
VCSRO77_1947	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCSRO77_1948	COG0512	Glutamine amidotransferase of anthranilate synthase
VCSRO77_1949	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VCSRO77_1950	COG0134	indole-3-glycerol-phosphate synthase activity
VCSRO77_1950	COG0135	phosphoribosylanthranilate isomerase activity
VCSRO77_1951	COG0133	tryptophan synthase activity
VCSRO77_1952	COG0159	tryptophan synthase activity
VCSRO77_1954	COG1435	thymidine kinase activity
VCSRO77_1955	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VCSRO77_1956	COG1801	Protein of unknown function DUF72
VCSRO77_1957	COG4106	trans-aconitate 2-methyltransferase activity
VCSRO77_1958	COG0500	methyltransferase
VCSRO77_1959	COG0189	ligase activity
VCSRO77_1959	COG4067	protein conserved in archaea
VCSRO77_1962	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VCSRO77_1964	COG3852	Histidine kinase
VCSRO77_1967	COG3070	regulator of competence-specific genes
VCSRO77_1969	COG2431	L-lysine efflux transmembrane transporter activity
VCSRO77_1971	COG0076	glutamate decarboxylase activity
VCSRO77_1972	COG1737	Transcriptional regulator
VCSRO77_1973	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO77_1973	COG1454	alcohol dehydrogenase
VCSRO77_1974	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCSRO77_1975	COG2985	domain, Protein
VCSRO77_1975	COG3273	potassium ion transport
VCSRO77_1976	COG0542	response to heat
VCSRO77_1977	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VCSRO77_1978	COG1278	Cold shock
VCSRO77_1980	COG1187	pseudouridine synthase activity
VCSRO77_1981	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VCSRO77_1981	COG0140	phosphoribosyl-ATP diphosphatase activity
VCSRO77_1982	COG0107	imidazoleglycerol-phosphate synthase activity
VCSRO77_1983	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VCSRO77_1984	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VCSRO77_1985	COG0131	Imidazoleglycerol-phosphate dehydratase
VCSRO77_1985	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCSRO77_1986	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VCSRO77_1987	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VCSRO77_1988	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VCSRO77_1989	COG1757	Na H antiporter
VCSRO77_1990	COG2916	Histone family protein nucleoid-structuring protein H-NS
VCSRO77_1991	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO77_1992	COG0482	sulfurtransferase activity
VCSRO77_1993	COG2915	High frequency lysogenization protein hflD homolog
VCSRO77_1994	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VCSRO77_1996	COG2268	Band 7 protein
VCSRO77_1998	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VCSRO77_2001	COG0300	oxidoreductase activity
VCSRO77_2003	COG0501	Belongs to the peptidase M48B family
VCSRO77_2005	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VCSRO77_2006	COG2226	methyltransferase
VCSRO77_2007	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO77_2008	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCSRO77_2009	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VCSRO77_2010	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VCSRO77_2011	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VCSRO77_2012	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VCSRO77_2013	COG0653	protein targeting
VCSRO77_2014	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO77_2015	COG2199	diguanylate cyclase activity
VCSRO77_2015	COG2203	Gaf domain
VCSRO77_2017	COG4120	Belongs to the binding-protein-dependent transport system permease family
VCSRO77_2019	COG4628	conserved protein (DUF2132)
VCSRO77_2020	COG3092	negative regulation of chromosome organization
VCSRO77_2021	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCSRO77_2022	COG0280	phosphate acetyltransferase
VCSRO77_2022	COG0857	belongs to the CobB CobQ family
VCSRO77_2023	COG0435	Glutathione S-transferase
VCSRO77_2024	COG4608	Belongs to the ABC transporter superfamily
VCSRO77_2025	COG0444	Belongs to the ABC transporter superfamily
VCSRO77_2026	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO77_2027	COG0601	transmembrane transport
VCSRO77_2031	COG2204	response regulator
VCSRO77_2032	COG3300	MHYT domain
VCSRO77_2032	COG5001	Diguanylate cyclase
VCSRO77_2033	COG4191	Histidine kinase
VCSRO77_2034	COG5002	protein histidine kinase activity
VCSRO77_2036	COG2201	protein-glutamate methylesterase activity
VCSRO77_2039	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO77_2042	COG1881	PFAM PEBP family protein
VCSRO77_2047	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO77_2048	COG0640	Transcriptional regulator
VCSRO77_2049	COG3706	GGDEF domain
VCSRO77_2053	COG1946	Acyl-CoA thioesterase
VCSRO77_2054	COG1522	sequence-specific DNA binding
VCSRO77_2056	COG0616	signal peptide processing
VCSRO77_2057	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO77_2058	COG2983	Belongs to the UPF0260 family
VCSRO77_2060	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VCSRO77_2061	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VCSRO77_2063	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VCSRO77_2064	COG2832	Protein of unknown function (DUF454)
VCSRO77_2066	COG0745	RESPONSE REGULATOR receiver
VCSRO77_2067	COG0583	DNA-binding transcription factor activity
VCSRO77_2068	COG0778	Nitroreductase
VCSRO77_2069	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCSRO77_2069	COG1024	Enoyl-CoA hydratase
VCSRO77_2070	COG0183	Belongs to the thiolase family
VCSRO77_2073	COG2067	long-chain fatty acid transport protein
VCSRO77_2075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VCSRO77_2076	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VCSRO77_2077	COG2982	Protein involved in outer membrane biogenesis
VCSRO77_2078	COG0572	uridine kinase
VCSRO77_2079	COG0489	protein tyrosine kinase activity
VCSRO77_2080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO77_2080	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO77_2082	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO77_2083	COG2217	Heavy metal translocating P-type atpase
VCSRO77_2084	COG0517	IMP dehydrogenase activity
VCSRO77_2084	COG0617	tRNA 3'-terminal CCA addition
VCSRO77_2084	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
VCSRO77_2085	COG2199	diguanylate cyclase activity
VCSRO77_2086	COG0314	molybdopterin synthase activity
VCSRO77_2087	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VCSRO77_2088	COG0315	cyclic pyranopterin monophosphate synthase activity
VCSRO77_2089	COG0521	Mo-molybdopterin cofactor biosynthetic process
VCSRO77_2090	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VCSRO77_2091	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VCSRO77_2092	COG2198	Histidine kinase
VCSRO77_2093	COG2204	response regulator
VCSRO77_2094	COG2204	response regulator
VCSRO77_2095	COG0556	nucleotide-excision repair
VCSRO77_2097	COG4657	Part of a membrane complex involved in electron transport
VCSRO77_2098	COG2878	Part of a membrane complex involved in electron transport
VCSRO77_2099	COG4656	Part of a membrane complex involved in electron transport
VCSRO77_2102	COG4660	Part of a membrane complex involved in electron transport
VCSRO77_2103	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VCSRO77_2104	COG0346	lactoylglutathione lyase activity
VCSRO77_2107	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VCSRO77_2108	COG2056	Na+-H+ antiporter family
VCSRO77_2109	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VCSRO77_2110	COG1286	toxin biosynthetic process
VCSRO77_2111	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VCSRO77_2112	COG0285	dihydrofolate synthase activity
VCSRO77_2113	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VCSRO77_2114	COG0101	tRNA pseudouridine synthase activity
VCSRO77_2117	COG1263	PTS System
VCSRO77_2117	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO77_2117	COG2190	(PTS) system
VCSRO77_2118	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VCSRO77_2119	COG1846	Transcriptional regulator
VCSRO77_2119	COG1940	carbohydrate kinase activity
VCSRO77_2120	COG4651	solute:proton antiporter activity
VCSRO77_2120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCSRO77_2121	COG0367	asparagine synthase
VCSRO77_2124	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VCSRO77_2125	COG0563	adenylate kinase activity
VCSRO77_2126	COG0326	Molecular chaperone. Has ATPase activity
VCSRO77_2127	COG3710	Transcriptional regulator
VCSRO77_2130	COG0622	Phosphoesterase
VCSRO77_2131	COG1090	epimerase
VCSRO77_2132	COG0300	oxidoreductase activity
VCSRO77_2133	COG3118	belongs to the thioredoxin family
VCSRO77_2134	COG0330	HflC and HflK could
VCSRO77_2135	COG1585	Membrane protein implicated in regulation of membrane protease activity
VCSRO77_2136	COG0789	Transcriptional regulator
VCSRO77_2138	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VCSRO77_2139	COG3115	cell septum assembly
VCSRO77_2140	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VCSRO77_2141	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VCSRO77_2142	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO77_2144	COG2190	(PTS) system
VCSRO77_2145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO77_2146	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCSRO77_2147	COG1702	phosphate starvation-inducible protein PhoH
VCSRO77_2148	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VCSRO77_2149	COG4535	Mg2 and Co2 transporter CorC
VCSRO77_2150	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VCSRO77_2151	COG2888	peptidyl-tyrosine sulfation
VCSRO77_2152	COG0495	leucyl-tRNA aminoacylation
VCSRO77_2153	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VCSRO77_2154	COG1466	dna polymerase III delta subunit
VCSRO77_2155	COG0799	negative regulation of ribosome biogenesis
VCSRO77_2156	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VCSRO77_2157	COG0768	penicillin binding
VCSRO77_2158	COG0772	Belongs to the SEDS family
VCSRO77_2159	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCSRO77_2160	COG1686	Belongs to the peptidase S11 family
VCSRO77_2161	COG2921	Belongs to the UPF0250 family
VCSRO77_2162	COG0321	lipoyl(octanoyl) transferase activity
VCSRO77_2163	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VCSRO77_2165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCSRO77_2170	COG1596	polysaccharide export
VCSRO77_2172	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCSRO77_2180	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
VCSRO77_2182	COG0438	transferase activity, transferring glycosyl groups
VCSRO77_2186	COG0438	transferase activity, transferring glycosyl groups
VCSRO77_2190	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VCSRO77_2191	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VCSRO77_2192	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VCSRO77_2193	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO77_2199	COG0366	Alpha amylase catalytic
VCSRO77_2200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO77_2200	COG1263	PTS System
VCSRO77_2201	COG1609	Transcriptional regulator
VCSRO77_2202	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCSRO77_2203	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VCSRO77_2204	COG2011	ABC-type metal ion transport system permease component
VCSRO77_2205	COG1464	Belongs to the NlpA lipoprotein family
VCSRO77_2206	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VCSRO77_2208	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCSRO77_2208	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCSRO77_2211	COG1611	Belongs to the LOG family
VCSRO77_2212	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO77_2213	COG2363	Small membrane protein
VCSRO77_2214	COG0583	DNA-binding transcription factor activity
VCSRO77_2215	COG0301	tRNA thio-modification
VCSRO77_2215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO77_2217	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VCSRO77_2218	COG1722	exodeoxyribonuclease VII activity
VCSRO77_2219	COG0142	geranyltranstransferase activity
VCSRO77_2220	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VCSRO77_2221	COG0564	pseudouridine synthase activity
VCSRO77_2222	COG3098	single-species biofilm formation
VCSRO77_2225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO77_2227	COG1671	Belongs to the UPF0178 family
VCSRO77_2228	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCSRO77_2229	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCSRO77_2230	COG0254	rRNA binding
VCSRO77_2231	COG1720	tRNA m6t6A37 methyltransferase activity
VCSRO77_2232	COG0442	prolyl-tRNA aminoacylation
VCSRO77_2236	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VCSRO77_2236	COG0047	phosphoribosylformylglycinamidine synthase activity
VCSRO77_2237	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VCSRO77_2239	COG0590	tRNA wobble adenosine to inosine editing
VCSRO77_2240	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCSRO77_2246	COG0484	heat shock protein binding
VCSRO77_2247	COG0443	Heat shock 70 kDa protein
VCSRO77_2248	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VCSRO77_2249	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VCSRO77_2250	COG0497	DNA recombination
VCSRO77_2251	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO77_2252	COG2914	Belongs to the UPF0125 (RnfH) family
VCSRO77_2253	COG2867	negative regulation of translational initiation
VCSRO77_2254	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VCSRO77_2256	COG0582	viral genome integration into host DNA
VCSRO77_2262	COG1518	maintenance of DNA repeat elements
VCSRO77_2265	COG3501	Rhs element vgr protein
VCSRO77_2280	COG2003	Belongs to the UPF0758 family
VCSRO77_2294	COG0514	ATP-dependent DNA helicase (RecQ)
VCSRO77_2298	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VCSRO77_2299	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VCSRO77_2300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCSRO77_2304	COG3051	citrate lyase alpha subunit
VCSRO77_2305	COG2301	Belongs to the HpcH HpaI aldolase family
VCSRO77_2307	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
VCSRO77_2309	COG3630	sodium ion export across plasma membrane
VCSRO77_2310	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO77_2310	COG5016	pyruvate
VCSRO77_2311	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCSRO77_2313	COG4565	transcriptional regulatory protein
VCSRO77_2316	COG0583	DNA-binding transcription factor activity
VCSRO77_2318	COG1115	amino acid carrier protein
VCSRO77_2319	COG2015	COG2015, Alkyl sulfatase and related hydrolases
VCSRO77_2320	COG0583	DNA-binding transcription factor activity
VCSRO77_2322	COG1120	ATPase activity
VCSRO77_2323	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO77_2324	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO77_2325	COG4592	Periplasmic binding protein
VCSRO77_2327	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO77_2328	COG1169	isochorismate synthase
VCSRO77_2329	COG1021	2,3-dihydroxybenzoate-AMP ligase
VCSRO77_2330	COG1535	isochorismatase
VCSRO77_2330	COG3433	isochorismatase activity
VCSRO77_2331	COG1584	GPR1 FUN34 yaaH family protein
VCSRO77_2333	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VCSRO77_2333	COG0519	Catalyzes the synthesis of GMP from XMP
VCSRO77_2334	COG0516	GMP reductase activity
VCSRO77_2334	COG0517	IMP dehydrogenase activity
VCSRO77_2335	COG1570	exodeoxyribonuclease VII activity
VCSRO77_2338	COG1160	GTP binding
VCSRO77_2339	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO77_2340	COG2976	Protein conserved in bacteria
VCSRO77_2341	COG0124	histidyl-tRNA synthetase
VCSRO77_2342	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VCSRO77_2343	COG1426	Protein conserved in bacteria
VCSRO77_2345	COG0105	UTP biosynthetic process
VCSRO77_2346	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCSRO77_2347	COG2975	iron-sulfur cluster assembly
VCSRO77_2348	COG0633	Ferredoxin
VCSRO77_2350	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VCSRO77_2352	COG0822	iron-sulfur transferase activity
VCSRO77_2354	COG1959	2 iron, 2 sulfur cluster binding
VCSRO77_2356	COG0483	inositol monophosphate 1-phosphatase activity
VCSRO77_2357	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO77_2358	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO77_2359	COG1862	Preprotein translocase
VCSRO77_2362	COG0517	IMP dehydrogenase activity
VCSRO77_2364	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VCSRO77_2365	COG0583	DNA-binding transcription factor activity
VCSRO77_2366	COG0450	alkyl hydroperoxide reductase
VCSRO77_2367	COG3142	Participates in the control of copper homeostasis
VCSRO77_2370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCSRO77_2371	COG0581	inorganic phosphate transmembrane transporter activity
VCSRO77_2373	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VCSRO77_2374	COG0248	Ppx GppA phosphatase
VCSRO77_2376	COG5002	protein histidine kinase activity
VCSRO77_2377	COG0745	RESPONSE REGULATOR receiver
VCSRO77_2379	COG0826	peptidase U32
VCSRO77_2380	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCSRO77_2388	COG0542	response to heat
VCSRO77_2389	COG1496	oxidoreductase activity
VCSRO77_2390	COG0564	pseudouridine synthase activity
VCSRO77_2391	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO77_2392	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCSRO77_2393	COG0077	Prephenate dehydratase
VCSRO77_2393	COG1605	Chorismate mutase
VCSRO77_2394	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCSRO77_2395	COG5001	Diguanylate cyclase
VCSRO77_2396	COG5001	Diguanylate cyclase
VCSRO77_2398	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VCSRO77_2400	COG0488	(ABC) transporter
VCSRO77_2402	COG0287	Prephenate dehydrogenase
VCSRO77_2402	COG1605	Chorismate mutase
VCSRO77_2403	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO77_2404	COG3275	phosphorelay sensor kinase activity
VCSRO77_2405	COG3279	Response regulator of the LytR AlgR family
VCSRO77_2407	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VCSRO77_2408	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCSRO77_2411	COG1966	Carbon starvation protein
VCSRO77_2412	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VCSRO77_2413	COG1047	Peptidyl-prolyl cis-trans
VCSRO77_2414	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VCSRO77_2416	COG0196	riboflavin kinase activity
VCSRO77_2417	COG0728	peptidoglycan biosynthetic process
VCSRO77_2418	COG0268	Binds directly to 16S ribosomal RNA
VCSRO77_2419	COG0640	Transcriptional regulator
VCSRO77_2420	COG0583	DNA-binding transcription factor activity
VCSRO77_2421	COG1283	sodium-dependent phosphate transmembrane transporter activity
VCSRO77_2423	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VCSRO77_2424	COG0730	response to heat
VCSRO77_2425	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
VCSRO77_2426	COG0494	nUDIX hydrolase
VCSRO77_2428	COG0667	Aldo Keto reductase
VCSRO77_2432	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VCSRO77_2433	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VCSRO77_2436	COG0513	Belongs to the DEAD box helicase family
VCSRO77_2455	COG3335	DDE superfamily endonuclease
VCSRO77_2462	COG2003	Belongs to the UPF0758 family
VCSRO77_2467	COG0714	Associated with various cellular activities
VCSRO77_2471	COG0629	single-stranded DNA binding
VCSRO77_2474	COG3328	transposase activity
VCSRO77_2480	COG0681	Belongs to the peptidase S26 family
VCSRO77_2483	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCSRO77_2492	COG3093	addiction module antidote protein HigA
VCSRO77_2501	COG3335	DDE superfamily endonuclease
VCSRO77_2510	COG3547	Transposase (IS116 IS110 IS902 family)
VCSRO77_2520	COG3153	acetyltransferase
VCSRO77_2521	COG3154	lipid carrier protein
VCSRO77_2523	COG0826	peptidase U32
VCSRO77_2524	COG0826	peptidase U32
VCSRO77_2529	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VCSRO77_2531	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VCSRO77_2532	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VCSRO77_2533	COG0195	Participates in both transcription termination and antitermination
VCSRO77_2534	COG0779	Required for maturation of 30S ribosomal subunits
VCSRO77_2537	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCSRO77_2540	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VCSRO77_2541	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VCSRO77_2542	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VCSRO77_2543	COG1534	Rna-binding protein
VCSRO77_2544	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO77_2545	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCSRO77_2546	COG2027	D-alanyl-D-alanine carboxypeptidase
VCSRO77_2547	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCSRO77_2548	COG0739	heme binding
VCSRO77_2549	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO77_2551	COG0316	Belongs to the HesB IscA family
VCSRO77_2552	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VCSRO77_2554	COG0628	permease
VCSRO77_2555	COG2813	Specifically methylates the guanine in position
VCSRO77_2557	COG0747	negative chemotaxis
VCSRO77_2559	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO77_2560	COG0444	Belongs to the ABC transporter superfamily
VCSRO77_2561	COG4608	Belongs to the ABC transporter superfamily
VCSRO77_2563	COG2971	BadF BadG BcrA BcrD
VCSRO77_2566	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCSRO77_2567	COG3842	ATPase activity
VCSRO77_2569	COG1840	ABC-type Fe3 transport system, periplasmic component
VCSRO77_2570	COG0004	ammonium transporteR
VCSRO77_2571	COG0347	Belongs to the P(II) protein family
VCSRO77_2572	COG3112	Uncharacterised protein family (UPF0231)
VCSRO77_2573	COG1049	propionate catabolic process, 2-methylcitrate cycle
VCSRO77_2574	COG1752	Esterase of the alpha-beta hydrolase superfamily
VCSRO77_2575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VCSRO77_2576	COG1643	Atp-dependent helicase
VCSRO77_2578	COG1489	DNA binding
VCSRO77_2580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCSRO77_2582	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCSRO77_2583	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VCSRO77_2584	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VCSRO77_2585	COG0842	Transport permease protein
VCSRO77_2586	COG1131	(ABC) transporter
VCSRO77_2587	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO77_2588	COG0288	reversible hydration of carbon dioxide
VCSRO77_2591	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VCSRO77_2592	COG3107	peptidoglycan biosynthetic process
VCSRO77_2593	COG0792	nuclease activity
VCSRO77_2594	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCSRO77_2595	COG2823	Periplasmic or secreted lipoprotein
VCSRO77_2596	COG2969	positive regulation of protein catabolic process
VCSRO77_2597	COG0625	glutathione transferase activity
VCSRO77_2598	COG2857	Cytochrome c1
VCSRO77_2599	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VCSRO77_2600	COG0723	plastoquinol--plastocyanin reductase activity
VCSRO77_2601	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VCSRO77_2602	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VCSRO77_2603	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VCSRO77_2605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCSRO77_2606	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCSRO77_2607	COG0335	large ribosomal subunit rRNA binding
VCSRO77_2608	COG0336	Belongs to the RNA methyltransferase TrmD family
VCSRO77_2609	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VCSRO77_2610	COG0228	four-way junction DNA binding
VCSRO77_2611	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VCSRO77_2613	COG4137	Cytochrome C assembly protein
VCSRO77_2614	COG4536	flavin adenine dinucleotide binding
VCSRO77_2615	COG1854	S-ribosylhomocysteine lyase activity
VCSRO77_2616	COG2918	glutathione biosynthetic process
VCSRO77_2617	COG0612	Peptidase, M16
VCSRO77_2618	COG1238	metal cluster binding
VCSRO77_2620	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCSRO77_2621	COG5016	pyruvate
VCSRO77_2621	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO77_2622	COG3630	sodium ion export across plasma membrane
VCSRO77_2631	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
VCSRO77_2632	COG0527	aspartate kinase activity
VCSRO77_2633	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VCSRO77_2634	COG2137	regulation of response to DNA damage stimulus
VCSRO77_2635	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VCSRO77_2637	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
VCSRO77_2638	COG4208	sulfate ABC transporter
VCSRO77_2642	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VCSRO77_2643	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VCSRO77_2644	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCSRO77_2646	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VCSRO77_2647	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VCSRO77_2648	COG0585	pseudouridine synthase activity
VCSRO77_2649	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VCSRO77_2650	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VCSRO77_2651	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VCSRO77_2652	COG1968	undecaprenyl-diphosphatase activity
VCSRO77_2653	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCSRO77_2654	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VCSRO77_2655	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VCSRO77_2657	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VCSRO77_2658	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VCSRO77_2659	COG1610	YqeY-like protein
VCSRO77_2660	COG0358	DNA primase activity
VCSRO77_2664	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCSRO77_2665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VCSRO77_2666	COG1349	DNA-binding transcription factor activity
VCSRO77_2671	COG1279	arginine transmembrane transporter activity
VCSRO77_2672	COG0668	transmembrane transport
VCSRO77_2673	COG0191	fructose-bisphosphate aldolase activity
VCSRO77_2674	COG0126	phosphoglycerate kinase activity
VCSRO77_2675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO77_2676	COG4771	TonB-dependent receptor
VCSRO77_2677	COG0583	DNA-binding transcription factor activity
VCSRO77_2678	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCSRO77_2679	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VCSRO77_2681	COG2356	endonuclease I
VCSRO77_2682	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VCSRO77_2683	COG0189	ligase activity
VCSRO77_2684	COG1678	Uncharacterized ACR, COG1678
VCSRO77_2685	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VCSRO77_2686	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCSRO77_2690	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VCSRO77_2691	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VCSRO77_2692	COG0762	integral membrane protein
VCSRO77_2693	COG1872	DUF167
VCSRO77_2695	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VCSRO77_2696	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VCSRO77_2697	COG2066	Belongs to the glutaminase family
VCSRO77_2698	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VCSRO77_2699	COG1194	a g-specific adenine glycosylase
VCSRO77_2700	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VCSRO77_2701	COG0741	lytic transglycosylase activity
VCSRO77_2712	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VCSRO77_2713	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VCSRO77_2714	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO77_2715	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VCSRO77_2716	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VCSRO77_2717	COG2967	ApaG domain
VCSRO77_2718	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VCSRO77_2720	COG3610	response to peptide
VCSRO77_2721	COG2966	Psort location CytoplasmicMembrane, score
VCSRO77_2722	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VCSRO77_2723	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VCSRO77_2724	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VCSRO77_2725	COG0142	geranyltranstransferase activity
VCSRO77_2726	COG0531	amino acid
VCSRO77_2727	COG0039	L-malate dehydrogenase activity
VCSRO77_2728	COG1438	arginine binding
VCSRO77_2729	COG2358	TRAP transporter, solute receptor (TAXI family
VCSRO77_2731	COG0589	response to stress
VCSRO77_2735	COG2235	arginine
VCSRO77_2736	COG0312	modulator of DNA gyrase
VCSRO77_2737	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VCSRO77_2738	COG3164	Protein of unknown function
VCSRO77_2740	COG0424	maF-like protein
VCSRO77_2741	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VCSRO77_2742	COG1792	Involved in formation and maintenance of cell shape
VCSRO77_2743	COG1077	Cell shape determining protein MreB Mrl
VCSRO77_2749	COG2165	general secretion pathway protein
VCSRO77_2751	COG2165	general secretion pathway protein
VCSRO77_2753	COG1459	type II secretion system
VCSRO77_2754	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO77_2756	COG3267	Type II secretory pathway component ExeA
VCSRO77_2756	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO77_2761	COG2199	diguanylate cyclase activity
VCSRO77_2761	COG2200	EAL domain
VCSRO77_2762	COG0629	single-stranded DNA binding
VCSRO77_2765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VCSRO77_2767	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCSRO77_2768	COG0527	aspartate kinase activity
VCSRO77_2769	COG1410	methionine synthase
VCSRO77_2769	COG0646	methionine synthase
VCSRO77_2784	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
VCSRO77_2785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCSRO77_2786	COG1739	Uncharacterized protein family UPF0029
VCSRO77_2787	COG1024	Enoyl-CoA hydratase
VCSRO77_2787	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCSRO77_2788	COG0183	Belongs to the thiolase family
VCSRO77_2789	COG0583	DNA-binding transcription factor activity
VCSRO77_2790	COG2814	Major facilitator Superfamily
VCSRO77_2792	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VCSRO77_2793	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VCSRO77_2794	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VCSRO77_2795	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VCSRO77_2796	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VCSRO77_2797	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VCSRO77_2799	COG0356	it plays a direct role in the translocation of protons across the membrane
VCSRO77_2800	COG3312	ion transport
VCSRO77_2801	COG1475	DNA binding
VCSRO77_2802	COG1192	Involved in chromosome partitioning
VCSRO77_2803	COG0357	Ribosomal RNA small subunit methyltransferase G
VCSRO77_2804	COG0445	tRNA wobble uridine modification
VCSRO77_2809	COG0217	transcriptional regulatory protein
VCSRO77_2810	COG2084	Dehydrogenase
VCSRO77_2813	COG2909	trisaccharide binding
VCSRO77_2814	COG0058	SHG alpha-glucan phosphorylase activity
VCSRO77_2815	COG1640	4-alpha-glucanotransferase
VCSRO77_2816	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VCSRO77_2818	COG3501	Rhs element vgr protein
VCSRO77_2819	COG4104	PAAR repeat-containing protein
VCSRO77_2825	COG0471	metal ion transport
VCSRO77_2826	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCSRO77_2835	COG0671	phosphoesterase, PA-phosphatase related
VCSRO77_2837	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VCSRO77_2839	COG1999	signal sequence binding
VCSRO77_2842	COG0786	glutamate:sodium symporter activity
VCSRO77_2846	COG1566	PFAM secretion protein HlyD family protein
VCSRO77_2851	COG0813	purine-nucleoside phosphorylase activity
VCSRO77_2852	COG3272	Protein of unknown function (DUF1722)
VCSRO77_2854	COG0415	Belongs to the DNA photolyase family
VCSRO77_2855	COG1388	LysM domain
VCSRO77_2855	COG1376	ErfK ybiS ycfS ynhG family protein
VCSRO77_2858	COG0513	Belongs to the DEAD box helicase family
VCSRO77_2859	COG1770	oligopeptidase
VCSRO77_2865	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCSRO77_2866	COG0573	inorganic phosphate transmembrane transporter activity
VCSRO77_2867	COG0581	inorganic phosphate transmembrane transporter activity
VCSRO77_2868	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCSRO77_2871	COG3314	Sporulation integral membrane protein YlbJ
VCSRO77_2872	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO77_2874	COG0739	heme binding
VCSRO77_2875	COG3300	MHYT domain
VCSRO77_2875	COG5001	Diguanylate cyclase
VCSRO77_2877	COG0583	DNA-binding transcription factor activity
VCSRO77_2878	COG2814	Major facilitator Superfamily
VCSRO77_2883	COG1301	dicarboxylic acid transport
VCSRO77_2885	COG1342	Belongs to the UPF0251 family
VCSRO77_2890	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VCSRO77_2891	COG0673	inositol 2-dehydrogenase activity
VCSRO77_2893	COG2200	EAL domain
VCSRO77_2893	COG2771	luxR family
VCSRO77_2894	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO77_2896	COG0564	pseudouridine synthase activity
VCSRO77_2909	COG3829	transcription factor binding
VCSRO77_2914	COG3501	Rhs element vgr protein
VCSRO77_2914	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO77_2918	COG1869	D-ribose catabolic process
VCSRO77_2919	COG1129	ABC transporter
VCSRO77_2920	COG1172	Belongs to the binding-protein-dependent transport system permease family
VCSRO77_2921	COG1879	ABC-type sugar transport system periplasmic component
VCSRO77_2922	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO77_2923	COG1609	Transcriptional regulator
VCSRO77_2925	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO77_2927	COG0584	glycerophosphoryl diester phosphodiesterase
VCSRO77_2928	COG2271	Major facilitator Superfamily
VCSRO77_2935	COG0579	oxidoreductase
VCSRO77_2937	COG0242	peptide deformylase activity
VCSRO77_2940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO77_2941	COG1609	Transcriptional regulator
VCSRO77_2942	COG1017	nitric oxide dioxygenase activity
VCSRO77_2942	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCSRO77_2943	COG1320	monovalent cation:proton antiporter activity
VCSRO77_2944	COG2212	antiporter activity
VCSRO77_2945	COG1863	multisubunit Na H antiporter MnhE subunit
VCSRO77_2946	COG0651	ATP synthesis coupled electron transport
VCSRO77_2947	COG1006	Multisubunit Na H antiporter MnhC subunit
VCSRO77_2948	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCSRO77_2948	COG2111	Na H antiporter
VCSRO77_2950	COG0589	response to stress
VCSRO77_2952	COG0814	amino acid
VCSRO77_2955	COG3530	Putative quorum-sensing-regulated virulence factor
VCSRO77_2957	COG5001	Diguanylate cyclase
VCSRO77_2957	COG5002	protein histidine kinase activity
VCSRO77_2958	COG1278	Cold shock
VCSRO77_2961	COG2304	oxidoreductase activity
VCSRO77_2965	COG0714	Associated with various cellular activities
VCSRO77_2966	COG0840	transmembrane signaling receptor activity
VCSRO77_2969	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO77_2970	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO77_2972	COG3604	Transcriptional regulator
VCSRO77_2973	COG1017	nitric oxide dioxygenase activity
VCSRO77_2973	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCSRO77_2974	COG1278	Cold shock
VCSRO77_2975	COG3036	rescue of stalled ribosome
VCSRO77_2980	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VCSRO77_2980	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VCSRO77_2981	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCSRO77_2983	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCSRO77_2985	COG0516	GMP reductase activity
VCSRO77_2986	COG4974	Belongs to the 'phage' integrase family
VCSRO77_2992	COG0513	Belongs to the DEAD box helicase family
VCSRO77_2993	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCSRO77_2994	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCSRO77_2995	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VCSRO77_2996	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VCSRO77_2997	COG0784	Response regulator, receiver
VCSRO77_2997	COG3437	response regulator, receiver
VCSRO77_2998	COG4191	Histidine kinase
VCSRO77_2998	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO77_3000	COG1757	Na H antiporter
VCSRO77_3001	COG2814	Major facilitator Superfamily
VCSRO77_3003	COG3706	GGDEF domain
VCSRO77_3004	COG3240	lipase activity
VCSRO77_3006	COG0840	transmembrane signaling receptor activity
VCSRO77_3007	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VCSRO77_3008	COG5380	lipid catabolic process
VCSRO77_3013	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO77_3014	COG4605	iron ion homeostasis
VCSRO77_3015	COG4604	ABC transporter, ATP-binding protein
VCSRO77_3016	COG2207	Transcriptional regulator
VCSRO77_3019	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCSRO77_3021	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VCSRO77_3023	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO77_3025	COG0583	DNA-binding transcription factor activity
VCSRO77_3028	COG0745	RESPONSE REGULATOR receiver
VCSRO77_3030	COG3623	hexulose-6-phosphate isomerase
VCSRO77_3031	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
VCSRO77_3032	COG0561	phosphatase activity
VCSRO77_3041	COG0745	RESPONSE REGULATOR receiver
VCSRO77_3042	COG5002	protein histidine kinase activity
VCSRO77_3046	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VCSRO77_3049	COG2814	Major facilitator Superfamily
VCSRO77_3052	COG1686	Belongs to the peptidase S11 family
VCSRO77_3057	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCSRO77_3057	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCSRO77_3058	COG0509	glycine decarboxylation via glycine cleavage system
VCSRO77_3059	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCSRO77_3061	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VCSRO77_3064	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VCSRO77_3065	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
VCSRO77_3069	COG1011	Hydrolase
VCSRO77_3075	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VCSRO77_3084	COG0432	Pfam Uncharacterised protein family UPF0047
VCSRO77_3093	COG0494	nUDIX hydrolase
VCSRO77_3095	COG2161	toxin-antitoxin pair type II binding
VCSRO77_3096	COG4115	mRNA cleavage
VCSRO77_3109	COG1418	mRNA catabolic process
VCSRO77_3118	COG0346	lactoylglutathione lyase activity
VCSRO77_3141	COG0384	phenazine biosynthesis protein PhzF
VCSRO77_3155	COG3549	Plasmid maintenance system killer
VCSRO77_3156	COG3093	addiction module antidote protein HigA
VCSRO77_3157	COG4977	sequence-specific DNA binding
VCSRO77_3184	COG3040	lipid binding
VCSRO77_3188	COG5642	Protein of unknown function (DUF2384)
VCSRO77_3189	COG1418	mRNA catabolic process
VCSRO77_3190	COG4977	sequence-specific DNA binding
VCSRO77_3200	COG1328	CTP reductase activity
VCSRO77_3201	COG0602	queuosine metabolic process
VCSRO77_3203	COG0189	ligase activity
VCSRO77_3203	COG4067	protein conserved in archaea
VCSRO77_3204	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO77_3204	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO77_3204	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VCSRO77_3205	COG1105	Belongs to the carbohydrate kinase PfkB family
VCSRO77_3206	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO77_3206	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO77_3207	COG1609	Transcriptional regulator
VCSRO77_3208	COG0420	3'-5' exonuclease activity
VCSRO77_3209	COG0419	ATPase involved in DNA repair
VCSRO77_3210	COG0784	Response regulator, receiver
VCSRO77_3210	COG2205	protein histidine kinase activity
VCSRO77_3211	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO77_3213	COG0038	chloride channel
VCSRO77_3214	COG0523	cobalamin synthesis protein
VCSRO77_3216	COG3158	transport of potassium into the cell
VCSRO77_3217	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
VCSRO77_3217	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VCSRO77_3217	COG0674	pyruvate-flavodoxin oxidoreductase activity
VCSRO77_3217	COG1013	pyruvate-flavodoxin oxidoreductase activity
VCSRO77_3218	COG2205	protein histidine kinase activity
VCSRO77_3219	COG0745	RESPONSE REGULATOR receiver
VCSRO77_3220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO77_3221	COG0586	Pfam SNARE associated Golgi protein
VCSRO77_3223	COG2200	EAL domain
VCSRO77_3225	COG3038	cytochrome b561
VCSRO77_3227	COG2116	formate transmembrane transporter activity
VCSRO77_3228	COG0583	DNA-binding transcription factor activity
VCSRO77_3230	COG3593	DNA synthesis involved in DNA repair
VCSRO77_3231	COG0737	Belongs to the 5'-nucleotidase family
VCSRO77_3235	COG2824	Alkylphosphonate utilization operon protein PhnA
VCSRO77_3241	COG2199	diguanylate cyclase activity
VCSRO77_3245	COG3706	GGDEF domain
VCSRO77_3248	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VCSRO77_3249	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VCSRO77_3251	COG0745	RESPONSE REGULATOR receiver
VCSRO77_3254	COG3140	Belongs to the UPF0181 family
VCSRO77_3255	COG0023	Translation Initiation Factor
VCSRO77_3259	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO77_3259	COG1042	CoA-binding domain protein
VCSRO77_3259	COG0045	succinate-CoA ligase (ADP-forming) activity
VCSRO77_3260	COG0583	DNA-binding transcription factor activity
VCSRO77_3261	COG4771	TonB-dependent receptor
VCSRO77_3264	COG2050	protein possibly involved in aromatic compounds catabolism
VCSRO77_3268	COG0625	glutathione transferase activity
VCSRO77_3271	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VCSRO77_3272	COG4172	Belongs to the ABC transporter superfamily
VCSRO77_3273	COG4239	(ABC) transporter, permease
VCSRO77_3274	COG4174	ABC transporter (Permease)
VCSRO77_3275	COG4166	transmembrane transport
VCSRO77_3280	COG3104	oligopeptide transport
VCSRO77_3284	COG3842	ATPase activity
VCSRO77_3285	COG1840	ABC-type Fe3 transport system, periplasmic component
VCSRO77_3286	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCSRO77_3287	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VCSRO77_3288	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO77_3289	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO77_3290	COG1011	Hydrolase
VCSRO77_3292	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VCSRO77_3293	COG1970	mechanosensitive ion channel activity
VCSRO77_3294	COG2759	Belongs to the formate--tetrahydrofolate ligase family
VCSRO77_3295	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO77_3295	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO77_3296	COG0302	gtp cyclohydrolase
VCSRO77_3298	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCSRO77_3300	COG2897	thiosulfate sulfurtransferase activity
VCSRO77_3301	COG2897	thiosulfate sulfurtransferase activity
VCSRO77_3302	COG2390	Transcriptional regulator
VCSRO77_3304	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCSRO77_3311	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO77_3316	COG0583	DNA-binding transcription factor activity
VCSRO77_3317	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
VCSRO77_3325	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCSRO77_3335	COG0745	RESPONSE REGULATOR receiver
VCSRO77_3336	COG1263	PTS System
VCSRO77_3336	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO77_3337	COG1609	Transcriptional regulator
VCSRO77_3338	COG1621	beta-fructofuranosidase activity
VCSRO77_3339	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO77_3340	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCSRO77_3344	COG4160	amino acid transport
VCSRO77_3345	COG4215	(ABC) transporter
VCSRO77_3346	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO77_3347	COG1126	abc transporter atp-binding protein
VCSRO77_3349	COG2425	protein containing a von Willebrand factor type A (vWA) domain
VCSRO77_3351	COG0494	nUDIX hydrolase
VCSRO77_3352	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VCSRO77_3354	COG1309	transcriptional regulator
VCSRO77_3355	COG0513	Belongs to the DEAD box helicase family
VCSRO77_3356	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
VCSRO77_3358	COG0814	amino acid
VCSRO77_3359	COG0840	transmembrane signaling receptor activity
VCSRO77_3360	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VCSRO77_3361	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
VCSRO77_3363	COG1984	allophanate hydrolase subunit 2
VCSRO77_3366	COG2932	Transcriptional regulator
VCSRO77_3367	COG3423	Transcriptional regulator
VCSRO77_3368	COG2801	Transposase and inactivated derivatives
VCSRO77_3369	COG2842	Transposition protein
VCSRO77_3390	COG0640	Transcriptional regulator
VCSRO77_3392	COG4373	Mu-like prophage FluMu protein gp28
VCSRO77_3393	COG4383	Mu-like prophage protein gp29
VCSRO77_3398	COG4397	Mu-like prophage major head subunit gpT
VCSRO77_3400	COG4387	Mu-like prophage protein GP36
VCSRO77_3404	COG4386	tail sheath protein
VCSRO77_3406	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
VCSRO77_3410	COG4384	Bacteriophage Mu Gp45 protein
VCSRO77_3412	COG3299	homolog of phage Mu protein gp47
VCSRO77_3413	COG3778	Protein conserved in bacteria
VCSRO77_3416	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VCSRO77_3417	COG4181	ATPase activity
VCSRO77_3419	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCSRO77_3420	COG1716	ATPase activity
VCSRO77_3420	COG5001	Diguanylate cyclase
VCSRO77_3422	COG0484	heat shock protein binding
VCSRO77_3426	COG0546	phosphoglycolate phosphatase activity
VCSRO77_3429	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO77_3430	COG1368	sulfuric ester hydrolase activity
VCSRO77_3432	COG0513	Belongs to the DEAD box helicase family
VCSRO77_3435	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCSRO77_3437	COG3046	protein related to deoxyribodipyrimidine photolyase
VCSRO77_3438	COG3397	chitin binding
VCSRO77_3439	COG3227	Zinc metalloprotease (Elastase)
VCSRO77_3441	COG0010	Belongs to the arginase family
VCSRO77_3442	COG1166	arginine decarboxylase activity
VCSRO77_3444	COG2239	Acts as a magnesium transporter
VCSRO77_3445	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCSRO77_3446	COG0459	protein refolding
VCSRO77_3448	COG0527	aspartate kinase activity
VCSRO77_3449	COG0662	Cupin 2, conserved barrel domain protein
VCSRO77_3450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VCSRO77_3451	COG0456	acetyltransferase
VCSRO77_3452	COG2154	pterin-4-alpha-carbinolamine dehydratase
VCSRO77_3453	COG3186	Phenylalanine-4-hydroxylase
VCSRO77_3454	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCSRO77_3457	COG2264	protein methyltransferase activity
VCSRO77_3461	COG2171	N-acyltransferase activity
VCSRO77_3462	COG1253	flavin adenine dinucleotide binding
VCSRO77_3463	COG1765	OsmC-like protein
VCSRO77_3468	COG0531	amino acid
VCSRO77_3471	COG3279	Response regulator of the LytR AlgR family
VCSRO77_3472	COG3275	phosphorelay sensor kinase activity
VCSRO77_3475	COG0577	efflux transmembrane transporter activity
VCSRO77_3475	COG1136	(ABC) transporter
VCSRO77_3476	COG1136	(ABC) transporter
VCSRO77_3478	COG4989	oxidoreductase activity
VCSRO77_3479	COG0366	Alpha amylase catalytic
VCSRO77_3480	COG2067	long-chain fatty acid transport protein
VCSRO77_3481	COG2267	carboxylic ester hydrolase activity
VCSRO77_3483	COG3227	Zinc metalloprotease (Elastase)
VCSRO77_3484	COG3047	cAMP biosynthetic process
VCSRO77_3487	COG1686	Belongs to the peptidase S11 family
VCSRO77_3488	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VCSRO77_3489	COG1271	oxidase subunit
VCSRO77_3490	COG1294	oxidase, subunit
VCSRO77_3493	COG3048	D-serine ammonia-lyase activity
VCSRO77_3494	COG0583	DNA-binding transcription factor activity
VCSRO77_3497	COG1063	alcohol dehydrogenase
VCSRO77_3500	COG2873	o-acetylhomoserine
VCSRO77_3502	COG0346	lactoylglutathione lyase activity
VCSRO77_3507	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO77_3508	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VCSRO77_3509	COG0363	glucosamine-6-phosphate deaminase activity
VCSRO77_3510	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VCSRO77_3515	COG1929	Belongs to the glycerate kinase type-1 family
VCSRO77_3516	COG2610	gluconate transmembrane transporter activity
VCSRO77_3517	COG3835	regulator
VCSRO77_3519	COG0748	coenzyme F420 binding
VCSRO77_3520	COG3721	Heme iron utilization protein
VCSRO77_3522	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCSRO77_3523	COG0811	peptide transport
VCSRO77_3524	COG0848	biopolymer transport protein
VCSRO77_3525	COG4558	Periplasmic binding protein
VCSRO77_3526	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO77_3527	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VCSRO77_3534	COG3217	Mosc domain protein beta barrel domain protein
VCSRO77_3534	COG0633	Ferredoxin
VCSRO77_3534	COG3217	Mosc domain protein beta barrel domain protein
VCSRO77_3534	COG0633	Ferredoxin
VCSRO77_3535	COG0418	dihydroorotase activity
VCSRO77_3537	COG3152	Membrane
VCSRO77_3539	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCSRO77_3540	COG2354	Protein conserved in bacteria
VCSRO77_3541	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO77_3542	COG1278	Cold shock
VCSRO77_3547	COG2199	diguanylate cyclase activity
VCSRO77_3548	COG1349	DNA-binding transcription factor activity
VCSRO77_3551	COG3833	ABC-type maltose transport systems, permease component
VCSRO77_3552	COG1175	transmembrane transport
VCSRO77_3554	COG3842	ATPase activity
VCSRO77_3555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO77_3558	COG0393	Putative heavy-metal-binding
VCSRO77_3560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO77_3561	COG0835	chemotaxis
VCSRO77_3561	COG0784	Response regulator, receiver
VCSRO77_3562	COG1846	Transcriptional regulator
VCSRO77_3563	COG3706	GGDEF domain
VCSRO77_3570	COG0583	DNA-binding transcription factor activity
VCSRO77_3571	COG5001	Diguanylate cyclase
VCSRO77_3573	COG1741	Belongs to the pirin family
VCSRO77_3574	COG3123	guanosine phosphorylase activity
VCSRO77_3576	COG2211	Major facilitator Superfamily
VCSRO77_3577	COG0840	transmembrane signaling receptor activity
VCSRO77_3578	COG1067	ATP-dependent peptidase activity
VCSRO77_3580	COG4172	Belongs to the ABC transporter superfamily
VCSRO77_3584	COG0583	DNA-binding transcription factor activity
VCSRO77_3585	COG1620	l-lactate permease
VCSRO77_3588	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
VCSRO77_3590	COG0840	transmembrane signaling receptor activity
VCSRO77_3592	COG0513	Belongs to the DEAD box helicase family
VCSRO77_3595	COG1538	Outer membrane efflux protein
VCSRO77_3600	COG2186	Transcriptional regulator
VCSRO77_3602	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCSRO77_3604	COG0246	Mannitol dehydrogenase
VCSRO77_3605	COG1904	glucuronate isomerase
VCSRO77_3606	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO77_3607	COG0800	Aldolase
VCSRO77_3611	COG1902	pentaerythritol trinitrate reductase activity
VCSRO77_3613	COG1132	(ABC) transporter
VCSRO77_3615	COG1902	pentaerythritol trinitrate reductase activity
VCSRO77_3617	COG1280	lysine exporter protein (LysE YggA)
VCSRO77_3618	COG2207	Transcriptional regulator
VCSRO77_3622	COG1846	Transcriptional regulator
VCSRO77_3623	COG1764	response to oxidative stress
VCSRO77_3624	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCSRO77_3625	COG0697	spore germination
VCSRO77_3627	COG0700	Nucleoside recognition
VCSRO77_3628	COG3366	ferrous iron transmembrane transporter activity
VCSRO77_3629	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
VCSRO77_3631	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VCSRO77_3632	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
VCSRO77_3633	COG2259	Doxx family
VCSRO77_3638	COG0363	glucosamine-6-phosphate deaminase activity
VCSRO77_3641	COG4580	involved in the transport of maltose and maltodextrins
VCSRO77_3647	COG0840	transmembrane signaling receptor activity
VCSRO77_3650	COG0840	transmembrane signaling receptor activity
VCSRO77_3652	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO77_3653	COG1126	abc transporter atp-binding protein
VCSRO77_3655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO77_3656	COG4597	amino acid ABC transporter
VCSRO77_3657	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCSRO77_3658	COG2213	PTS system mannitol-specific
VCSRO77_3658	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO77_3659	COG0246	Mannitol dehydrogenase
VCSRO77_3660	COG3722	fumarate hydratase activity
VCSRO77_3661	COG0673	inositol 2-dehydrogenase activity
VCSRO77_3666	COG0697	spore germination
VCSRO77_3667	COG1846	Transcriptional regulator
VCSRO77_3669	COG1335	isochorismatase
VCSRO77_3671	COG2910	NAD(P)H-binding
VCSRO77_3673	COG0840	transmembrane signaling receptor activity
VCSRO77_3674	COG4221	oxidoreductase activity
VCSRO77_3676	COG1901	pseudouridine methyltransferase
VCSRO77_3678	COG0531	amino acid
VCSRO77_3679	COG1982	Orn Lys Arg decarboxylase major
VCSRO77_3684	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCSRO77_3690	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VCSRO77_3698	COG0745	RESPONSE REGULATOR receiver
VCSRO77_3703	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCSRO77_3704	COG0840	transmembrane signaling receptor activity
VCSRO77_3705	COG0835	chemotaxis
VCSRO77_3706	COG0835	chemotaxis
VCSRO77_3707	COG0643	Histidine kinase
VCSRO77_3707	COG2198	Histidine kinase
VCSRO77_3711	COG0601	transmembrane transport
VCSRO77_3712	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO77_3714	COG0642	Histidine kinase
VCSRO77_3717	COG4221	oxidoreductase activity
VCSRO77_3721	COG1444	tRNA N-acetyltransferase activity
VCSRO77_3722	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine