locus-tag	class	description
VCSRO96_0001	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCSRO96_0002	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
VCSRO96_0003	COG0706	membrane insertase activity
VCSRO96_0004	COG0594	ribonuclease P activity
VCSRO96_0005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VCSRO96_0006	COG1126	abc transporter atp-binding protein
VCSRO96_0009	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VCSRO96_0010	COG0592	DNA-directed DNA polymerase activity
VCSRO96_0011	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VCSRO96_0012	COG0187	DNA topoisomerase II activity
VCSRO96_0015	COG0071	Belongs to the small heat shock protein (HSP20) family
VCSRO96_0016	COG3977	Valine--pyruvate aminotransferase
VCSRO96_0017	COG0751	glycine-tRNA ligase activity
VCSRO96_0018	COG0752	glycyl-tRNA synthetase alpha subunit
VCSRO96_0019	COG2119	membrane
VCSRO96_0022	COG0425	Belongs to the sulfur carrier protein TusA family
VCSRO96_0024	COG0604	alcohol dehydrogenase
VCSRO96_0026	COG0129	dihydroxy-acid dehydratase activity
VCSRO96_0027	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCSRO96_0030	COG0606	chelatase, subunit chli
VCSRO96_0031	COG0204	Acyl-transferase
VCSRO96_0032	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCSRO96_0033	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VCSRO96_0035	COG3084	Protein conserved in bacteria
VCSRO96_0036	COG4326	sporulation control protein
VCSRO96_0037	COG1272	protein, Hemolysin III
VCSRO96_0039	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCSRO96_0040	COG0569	domain protein
VCSRO96_0041	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VCSRO96_0041	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCSRO96_0042	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VCSRO96_0043	COG0242	peptide deformylase activity
VCSRO96_0044	COG1652	LysM domain
VCSRO96_0045	COG0758	DNA mediated transformation
VCSRO96_0046	COG2922	Belongs to the Smg family
VCSRO96_0047	COG0551	DNA topoisomerase type I activity
VCSRO96_0048	COG3385	transposase activity
VCSRO96_0049	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VCSRO96_0050	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VCSRO96_0051	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO96_0052	COG0408	coproporphyrinogen oxidase activity
VCSRO96_0053	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VCSRO96_0055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VCSRO96_0062	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VCSRO96_0063	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VCSRO96_0064	COG0352	thiamine-phosphate diphosphorylase activity
VCSRO96_0065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCSRO96_0066	COG2104	thiamine diphosphate biosynthetic process
VCSRO96_0067	COG2022	thiamine diphosphate biosynthetic process
VCSRO96_0068	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCSRO96_0070	COG2801	Transposase and inactivated derivatives
VCSRO96_0071	COG0006	proline dipeptidase activity
VCSRO96_0071	COG0006	proline dipeptidase activity
VCSRO96_0075	COG1522	sequence-specific DNA binding
VCSRO96_0076	COG5001	Diguanylate cyclase
VCSRO96_0076	COG5002	protein histidine kinase activity
VCSRO96_0080	COG0589	response to stress
VCSRO96_0081	COG1528	Iron-storage protein
VCSRO96_0083	COG2081	HI0933 family
VCSRO96_0085	COG1322	Protein conserved in bacteria
VCSRO96_0086	COG2226	methyltransferase
VCSRO96_0089	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO96_0090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO96_0091	COG0805	protein transport
VCSRO96_0092	COG1858	cytochrome C peroxidase
VCSRO96_0093	COG0534	Mate efflux family protein
VCSRO96_0095	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VCSRO96_0096	COG2937	Belongs to the GPAT DAPAT family
VCSRO96_0097	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VCSRO96_0098	COG3161	chorismate lyase activity
VCSRO96_0099	COG1580	Controls the rotational direction of flagella during chemotaxis
VCSRO96_0100	COG0840	transmembrane signaling receptor activity
VCSRO96_0102	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO96_0106	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO96_0106	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO96_0110	COG3078	GTPase activator activity
VCSRO96_0113	COG3071	HemY protein
VCSRO96_0114	COG2959	enzyme of heme biosynthesis
VCSRO96_0115	COG1587	Uroporphyrinogen-III synthase
VCSRO96_0116	COG0181	hydroxymethylbilane synthase activity
VCSRO96_0118	COG1965	Belongs to the frataxin family
VCSRO96_0119	COG0019	diaminopimelate decarboxylase activity
VCSRO96_0120	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VCSRO96_0122	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VCSRO96_0123	COG1011	Hydrolase
VCSRO96_0124	COG2200	EAL domain
VCSRO96_0124	COG3287	FIST C domain
VCSRO96_0124	COG2199	diguanylate cyclase activity
VCSRO96_0127	COG0561	phosphatase activity
VCSRO96_0128	COG2267	carboxylic ester hydrolase activity
VCSRO96_0129	COG1280	lysine exporter protein (LysE YggA)
VCSRO96_0130	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCSRO96_0131	COG0783	Belongs to the Dps family
VCSRO96_0136	COG0742	ribosomal rna small subunit methyltransferase
VCSRO96_0137	COG0552	protein localization to endoplasmic reticulum
VCSRO96_0138	COG2884	Cell division ATP-binding protein ftsE
VCSRO96_0139	COG2177	Part of the ABC transporter FtsEX involved in
VCSRO96_0140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCSRO96_0142	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO96_0145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCSRO96_0146	COG4206	TonB-dependent receptor
VCSRO96_0147	COG1404	Belongs to the peptidase S8 family
VCSRO96_0148	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
VCSRO96_0162	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VCSRO96_0163	COG5001	Diguanylate cyclase
VCSRO96_0163	COG3300	MHYT domain
VCSRO96_0165	COG3852	Histidine kinase
VCSRO96_0167	COG0174	glutamine synthetase
VCSRO96_0169	COG1217	gtp-binding protein TYPA
VCSRO96_0171	COG1295	ribonuclease BN
VCSRO96_0172	COG1490	D-aminoacyl-tRNA deacylase activity
VCSRO96_0173	COG0456	acetyltransferase
VCSRO96_0175	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
VCSRO96_0176	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VCSRO96_0177	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VCSRO96_0178	COG3031	protein transport across the cell outer membrane
VCSRO96_0180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO96_0181	COG1459	type II secretion system
VCSRO96_0182	COG2165	general secretion pathway protein
VCSRO96_0183	COG2165	general secretion pathway protein
VCSRO96_0184	COG2165	general secretion pathway protein
VCSRO96_0185	COG4795	General secretion pathway protein
VCSRO96_0186	COG3156	type II secretion system protein K
VCSRO96_0187	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCSRO96_0188	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCSRO96_0190	COG1218	3'(2'),5'-bisphosphate nucleotidase
VCSRO96_0191	COG0494	nUDIX hydrolase
VCSRO96_0193	COG1040	competence protein
VCSRO96_0194	COG0596	Alpha beta hydrolase
VCSRO96_0196	COG2183	response to ionizing radiation
VCSRO96_0197	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO96_0202	COG1129	ABC transporter
VCSRO96_0203	COG1172	Belongs to the binding-protein-dependent transport system permease family
VCSRO96_0204	COG1472	Belongs to the glycosyl hydrolase 3 family
VCSRO96_0208	COG2233	PERMEase
VCSRO96_0209	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VCSRO96_0210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCSRO96_0211	COG1758	RNA polymerase activity
VCSRO96_0212	COG0194	GDP metabolic process
VCSRO96_0213	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VCSRO96_0214	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCSRO96_0218	COG4232	protein-disulfide reductase activity
VCSRO96_0220	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCSRO96_0221	COG1027	Aspartate ammonia-lyase
VCSRO96_0222	COG3706	GGDEF domain
VCSRO96_0223	COG3030	protein affecting phage T7 exclusion by the F plasmid
VCSRO96_0224	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VCSRO96_0226	COG2205	protein histidine kinase activity
VCSRO96_0227	COG0745	RESPONSE REGULATOR receiver
VCSRO96_0229	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VCSRO96_0230	COG0205	6-phosphofructokinase activity
VCSRO96_0231	COG1494	fructose-1,6-bisphosphatase
VCSRO96_0232	COG3074	FtsZ-dependent cytokinesis
VCSRO96_0233	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VCSRO96_0234	COG0527	aspartate kinase activity
VCSRO96_0234	COG0460	homoserine dehydrogenase
VCSRO96_0235	COG0626	cystathionine gamma-synthase activity
VCSRO96_0236	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
VCSRO96_0237	COG0281	malic enzyme
VCSRO96_0238	COG0254	rRNA binding
VCSRO96_0239	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VCSRO96_0240	COG1609	Transcriptional regulator
VCSRO96_0241	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCSRO96_0242	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VCSRO96_0243	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VCSRO96_0244	COG1575	Belongs to the MenA family. Type 1 subfamily
VCSRO96_0245	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCSRO96_0246	COG0534	Mate efflux family protein
VCSRO96_0247	COG0149	triose-phosphate isomerase activity
VCSRO96_0252	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCSRO96_0253	COG0459	protein refolding
VCSRO96_0255	COG1509	lysine 2,3-aminomutase activity
VCSRO96_0256	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCSRO96_0258	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VCSRO96_0259	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VCSRO96_0260	COG1053	succinate dehydrogenase
VCSRO96_0261	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VCSRO96_0262	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO96_0263	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VCSRO96_0264	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VCSRO96_0265	COG1045	serine acetyltransferase
VCSRO96_0268	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VCSRO96_0269	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VCSRO96_0270	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VCSRO96_0271	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCSRO96_0272	COG0137	argininosuccinate synthase activity
VCSRO96_0273	COG0165	Argininosuccinate lyase
VCSRO96_0275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO96_0276	COG0678	peroxiredoxin activity
VCSRO96_0276	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCSRO96_0278	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VCSRO96_0284	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VCSRO96_0285	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VCSRO96_0287	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VCSRO96_0288	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VCSRO96_0289	COG0546	phosphoglycolate phosphatase activity
VCSRO96_0290	COG0180	Tryptophanyl-tRNA synthetase
VCSRO96_0293	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCSRO96_0295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VCSRO96_0297	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO96_0300	COG2801	Transposase and inactivated derivatives
VCSRO96_0302	COG3954	Phosphoribulokinase
VCSRO96_0304	COG0429	hydrolase of the alpha beta-hydrolase fold
VCSRO96_0306	COG0488	(ABC) transporter
VCSRO96_0307	COG2249	NAD(P)H dehydrogenase (quinone) activity
VCSRO96_0310	COG1047	Peptidyl-prolyl cis-trans
VCSRO96_0312	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VCSRO96_0313	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VCSRO96_0314	COG3083	sulfuric ester hydrolase activity
VCSRO96_0315	COG0557	exoribonuclease II activity
VCSRO96_0316	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCSRO96_0318	COG0051	transcription antitermination factor activity, RNA binding
VCSRO96_0319	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VCSRO96_0320	COG0088	Forms part of the polypeptide exit tunnel
VCSRO96_0321	COG0089	rRNA binding
VCSRO96_0322	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VCSRO96_0323	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VCSRO96_0324	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VCSRO96_0325	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VCSRO96_0326	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VCSRO96_0327	COG0255	Belongs to the universal ribosomal protein uL29 family
VCSRO96_0328	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VCSRO96_0329	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VCSRO96_0330	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VCSRO96_0331	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VCSRO96_0332	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VCSRO96_0333	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VCSRO96_0335	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VCSRO96_0336	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VCSRO96_0337	COG1841	ribosomal large subunit assembly
VCSRO96_0339	COG0201	protein transport
VCSRO96_0340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCSRO96_0341	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VCSRO96_0342	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VCSRO96_0343	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VCSRO96_0344	COG0202	RNA polymerase activity
VCSRO96_0345	COG0203	ribosomal protein L17
VCSRO96_0347	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO96_0348	COG3266	domain, Protein
VCSRO96_0348	COG3061	Opacity-associated protein A
VCSRO96_0349	COG0697	spore germination
VCSRO96_0350	COG2153	protein acetylation
VCSRO96_0351	COG0513	Belongs to the DEAD box helicase family
VCSRO96_0353	COG0737	Belongs to the 5'-nucleotidase family
VCSRO96_0354	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VCSRO96_0354	COG1648	precorrin-2 dehydrogenase activity
VCSRO96_0355	COG0175	sulfate reduction
VCSRO96_0356	COG2895	sulfate adenylyltransferase (ATP) activity
VCSRO96_0357	COG0529	Catalyzes the synthesis of activated sulfate
VCSRO96_0361	COG0577	efflux transmembrane transporter activity
VCSRO96_0361	COG1136	(ABC) transporter
VCSRO96_0364	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VCSRO96_0365	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO96_0366	COG0729	surface antigen
VCSRO96_0368	COG2105	PFAM AIG2 family protein
VCSRO96_0369	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VCSRO96_0371	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCSRO96_0372	COG0163	prenyltransferase activity
VCSRO96_0374	COG1178	ABC-type Fe3 transport system permease component
VCSRO96_0375	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VCSRO96_0376	COG3028	Belongs to the UPF0307 family
VCSRO96_0377	COG0312	modulator of DNA gyrase
VCSRO96_0378	COG2239	Acts as a magnesium transporter
VCSRO96_0379	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO96_0380	COG1660	Displays ATPase and GTPase activities
VCSRO96_0381	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO96_0382	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCSRO96_0384	COG1137	ATPase activity
VCSRO96_0385	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VCSRO96_0388	COG0517	IMP dehydrogenase activity
VCSRO96_0388	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VCSRO96_0390	COG1127	ABC transporter
VCSRO96_0391	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VCSRO96_0392	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCSRO96_0393	COG2854	intermembrane phospholipid transfer
VCSRO96_0395	COG5007	Belongs to the BolA IbaG family
VCSRO96_0396	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VCSRO96_0397	COG0204	Acyl-transferase
VCSRO96_0398	COG0251	oxidation-reduction process
VCSRO96_0400	COG0540	Belongs to the ATCase OTCase family
VCSRO96_0402	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VCSRO96_0403	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VCSRO96_0404	COG0564	pseudouridine synthase activity
VCSRO96_0405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCSRO96_0407	COG3385	transposase activity
VCSRO96_0408	COG0525	valine-tRNA ligase activity
VCSRO96_0409	COG2927	DNA polymerase III (CHI subunit)
VCSRO96_0410	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCSRO96_0411	COG0795	lipopolysaccharide-transporting ATPase activity
VCSRO96_0412	COG0795	lipopolysaccharide-transporting ATPase activity
VCSRO96_0415	COG3437	response regulator, receiver
VCSRO96_0424	COG0066	3-isopropylmalate dehydratase activity
VCSRO96_0425	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
VCSRO96_0426	COG0473	3-isopropylmalate dehydrogenase activity
VCSRO96_0431	COG0583	DNA-binding transcription factor activity
VCSRO96_0432	COG1022	Amp-dependent synthetase and ligase
VCSRO96_0433	COG0028	Belongs to the TPP enzyme family
VCSRO96_0434	COG0440	acetolactate synthase activity
VCSRO96_0435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO96_0436	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VCSRO96_0437	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VCSRO96_0438	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VCSRO96_0439	COG3079	Belongs to the UPF0149 family
VCSRO96_0440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO96_0441	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO96_0444	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VCSRO96_0446	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VCSRO96_0447	COG1595	DNA-templated transcription, initiation
VCSRO96_0450	COG3086	response to oxidative stress
VCSRO96_0451	COG0481	GTPase activity
VCSRO96_0453	COG0571	ribonuclease III activity
VCSRO96_0454	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VCSRO96_0455	COG1381	Involved in DNA repair and RecF pathway recombination
VCSRO96_0456	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VCSRO96_0461	COG5001	Diguanylate cyclase
VCSRO96_0464	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCSRO96_0465	COG3956	TIGRFAM MazG family protein
VCSRO96_0466	COG0504	CTP synthase activity
VCSRO96_0467	COG0148	phosphopyruvate hydratase activity
VCSRO96_0468	COG0617	tRNA 3'-terminal CCA addition
VCSRO96_0469	COG3267	Type II secretory pathway component ExeA
VCSRO96_0469	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO96_0471	COG4991	sh3 domain protein
VCSRO96_0472	COG0306	phosphate transporter
VCSRO96_0473	COG1392	Phosphate transport regulator
VCSRO96_0474	COG3025	triphosphatase activity
VCSRO96_0475	COG3385	transposase activity
VCSRO96_0477	COG0840	transmembrane signaling receptor activity
VCSRO96_0478	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VCSRO96_0480	COG1538	Outer membrane efflux protein
VCSRO96_0481	COG0494	nUDIX hydrolase
VCSRO96_0482	COG3151	Protein conserved in bacteria
VCSRO96_0484	COG3150	esterase
VCSRO96_0485	COG0187	DNA topoisomerase II activity
VCSRO96_0486	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VCSRO96_0488	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VCSRO96_0489	COG0237	dephospho-CoA kinase activity
VCSRO96_0491	COG1459	type II secretion system
VCSRO96_0492	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO96_0496	COG0716	FMN binding
VCSRO96_0497	COG4974	Belongs to the 'phage' integrase family
VCSRO96_0498	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCSRO96_0499	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VCSRO96_0500	COG0737	Belongs to the 5'-nucleotidase family
VCSRO96_0501	COG2186	Transcriptional regulator
VCSRO96_0502	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VCSRO96_0503	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCSRO96_0504	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO96_0506	COG3116	cell division
VCSRO96_0507	COG0768	penicillin binding
VCSRO96_0508	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VCSRO96_0509	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VCSRO96_0511	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VCSRO96_0512	COG0772	Belongs to the SEDS family
VCSRO96_0514	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCSRO96_0515	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VCSRO96_0516	COG0849	cell division
VCSRO96_0517	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VCSRO96_0518	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VCSRO96_0520	COG0653	protein targeting
VCSRO96_0521	COG0494	nUDIX hydrolase
VCSRO96_0522	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
VCSRO96_0523	COG0505	Belongs to the CarA family
VCSRO96_0524	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VCSRO96_0527	COG0730	response to heat
VCSRO96_0528	COG0583	DNA-binding transcription factor activity
VCSRO96_0529	COG2860	membrane
VCSRO96_0530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VCSRO96_0532	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VCSRO96_0534	COG0493	'glutamate synthase
VCSRO96_0535	COG0069	glutamate synthase activity
VCSRO96_0535	COG0070	glutamate synthase
VCSRO96_0535	COG0067	glutamate synthase
VCSRO96_0537	COG0067	glutamate synthase
VCSRO96_0537	COG0069	glutamate synthase activity
VCSRO96_0537	COG0070	glutamate synthase
VCSRO96_0538	COG1242	4 iron, 4 sulfur cluster binding
VCSRO96_0539	COG3706	GGDEF domain
VCSRO96_0539	COG4251	negative regulation of phosphorylation
VCSRO96_0539	COG5001	Diguanylate cyclase
VCSRO96_0539	COG2203	Gaf domain
VCSRO96_0540	COG0784	Response regulator, receiver
VCSRO96_0540	COG2198	Histidine kinase
VCSRO96_0540	COG5002	protein histidine kinase activity
VCSRO96_0541	COG0745	RESPONSE REGULATOR receiver
VCSRO96_0543	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCSRO96_0546	COG0083	homoserine kinase activity
VCSRO96_0547	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VCSRO96_0548	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VCSRO96_0549	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VCSRO96_0550	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VCSRO96_0553	COG1115	amino acid carrier protein
VCSRO96_0554	COG3022	response to hydroperoxide
VCSRO96_0556	COG0084	hydrolase, TatD family'
VCSRO96_0557	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO96_0558	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VCSRO96_0559	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO96_0560	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VCSRO96_0561	COG0813	purine-nucleoside phosphorylase activity
VCSRO96_0563	COG0560	Phosphoserine phosphatase
VCSRO96_0565	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VCSRO96_0566	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCSRO96_0567	COG1022	Amp-dependent synthetase and ligase
VCSRO96_0570	COG3250	beta-galactosidase activity
VCSRO96_0571	COG1609	Transcriptional regulator
VCSRO96_0572	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO96_0575	COG0189	ligase activity
VCSRO96_0575	COG0569	domain protein
VCSRO96_0579	COG2171	N-acyltransferase activity
VCSRO96_0580	COG3141	response to X-ray
VCSRO96_0583	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VCSRO96_0584	COG1074	ATP-dependent DNA helicase activity
VCSRO96_0585	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VCSRO96_0587	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCSRO96_0587	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VCSRO96_0589	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VCSRO96_0590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VCSRO96_0591	COG2166	iron-sulfur cluster assembly
VCSRO96_0592	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCSRO96_0593	COG0693	protein deglycase activity
VCSRO96_0594	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VCSRO96_0595	COG3385	transposase activity
VCSRO96_0596	COG3248	Nucleoside-binding outer membrane protein
VCSRO96_0598	COG1595	DNA-templated transcription, initiation
VCSRO96_0600	COG2211	Major facilitator Superfamily
VCSRO96_0601	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCSRO96_0603	COG2813	Specifically methylates the guanine in position
VCSRO96_0604	COG0271	Belongs to the BolA IbaG family
VCSRO96_0605	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO96_0606	COG1805	sodium ion transport
VCSRO96_0607	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO96_0608	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO96_0609	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO96_0610	COG2871	sodium ion transport
VCSRO96_0611	COG1477	protein flavinylation
VCSRO96_0615	COG3706	GGDEF domain
VCSRO96_0616	COG0733	neurotransmitter:sodium symporter activity
VCSRO96_0617	COG3385	transposase activity
VCSRO96_0619	COG0189	ligase activity
VCSRO96_0620	COG0189	ligase activity
VCSRO96_0620	COG4067	protein conserved in archaea
VCSRO96_0621	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO96_0622	COG2252	PERMEase
VCSRO96_0623	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VCSRO96_0624	COG1073	alpha beta
VCSRO96_0626	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VCSRO96_0627	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VCSRO96_0628	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VCSRO96_0629	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO96_0629	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO96_0632	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VCSRO96_0633	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCSRO96_0634	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VCSRO96_0635	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VCSRO96_0637	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VCSRO96_0638	COG0024	Methionine aminopeptidase
VCSRO96_0639	COG0052	Belongs to the universal ribosomal protein uS2 family
VCSRO96_0640	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VCSRO96_0641	COG0528	UMP kinase activity
VCSRO96_0642	COG0233	cytoplasmic translational termination
VCSRO96_0643	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VCSRO96_0644	COG0575	Belongs to the CDS family
VCSRO96_0645	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VCSRO96_0646	COG0750	zinc metalloprotease
VCSRO96_0648	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VCSRO96_0649	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO96_0650	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCSRO96_0651	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO96_0652	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO96_0653	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
VCSRO96_0654	COG0587	DNA-directed DNA polymerase activity
VCSRO96_0655	COG0825	malonyl-CoA metabolic process
VCSRO96_0656	COG0037	tRNA processing
VCSRO96_0658	COG3479	Phenolic acid decarboxylase
VCSRO96_0659	COG0347	Belongs to the P(II) protein family
VCSRO96_0660	COG3021	interspecies interaction between organisms
VCSRO96_0661	COG0741	lytic transglycosylase activity
VCSRO96_0661	COG1388	LysM domain
VCSRO96_0662	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCSRO96_0663	COG2226	methyltransferase
VCSRO96_0664	COG0328	RNA-DNA hybrid ribonuclease activity
VCSRO96_0667	COG3385	transposase activity
VCSRO96_0668	COG1960	acyl-CoA dehydrogenase activity
VCSRO96_0669	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCSRO96_0670	COG0121	glutamine amidotransferase
VCSRO96_0671	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VCSRO96_0672	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VCSRO96_0673	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VCSRO96_0675	COG1187	pseudouridine synthase activity
VCSRO96_0676	COG2840	Smr protein MutS2
VCSRO96_0682	COG2217	Heavy metal translocating P-type atpase
VCSRO96_0682	COG2608	mercury ion transmembrane transporter activity
VCSRO96_0683	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCSRO96_0686	COG1629	transport
VCSRO96_0686	COG4774	siderophore transport
VCSRO96_0687	COG2375	cellular response to nickel ion
VCSRO96_0688	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCSRO96_0688	COG2226	methyltransferase
VCSRO96_0688	COG3433	isochorismatase activity
VCSRO96_0695	COG0784	Response regulator, receiver
VCSRO96_0695	COG0835	chemotaxis
VCSRO96_0696	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCSRO96_0697	COG1815	bacterial-type flagellum-dependent cell motility
VCSRO96_0700	COG1749	Flagellar hook protein flgE
VCSRO96_0701	COG4787	bacterial-type flagellum-dependent cell motility
VCSRO96_0703	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VCSRO96_0704	COG1706	bacterial-type flagellum-dependent cell motility
VCSRO96_0705	COG3951	Flagellar rod assembly protein muramidase FlgJ
VCSRO96_0705	COG1705	Flagellar rod assembly protein muramidase FlgJ
VCSRO96_0708	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO96_0709	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO96_0726	COG0012	GTP binding
VCSRO96_0727	COG0193	aminoacyl-tRNA hydrolase activity
VCSRO96_0728	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VCSRO96_0729	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VCSRO96_0730	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VCSRO96_0731	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VCSRO96_0732	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VCSRO96_0733	COG2890	protein-(glutamine-N5) methyltransferase activity
VCSRO96_0735	COG2912	Transglutaminase-like superfamily
VCSRO96_0736	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VCSRO96_0737	COG0737	Belongs to the 5'-nucleotidase family
VCSRO96_0738	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VCSRO96_0739	COG2233	PERMEase
VCSRO96_0743	COG1393	Belongs to the ArsC family
VCSRO96_0744	COG4783	chaperone-mediated protein folding
VCSRO96_0748	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VCSRO96_0751	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VCSRO96_0753	COG1876	peptidase activity
VCSRO96_0755	COG1393	Belongs to the ArsC family
VCSRO96_0759	COG2837	iron assimilation
VCSRO96_0760	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO96_0761	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO96_0762	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO96_0763	COG1334	flagellar protein FlaG
VCSRO96_0764	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VCSRO96_0766	COG1516	flagellar protein fliS
VCSRO96_0770	COG1677	Flagellar hook-basal body complex protein FliE
VCSRO96_0772	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VCSRO96_0773	COG1317	bacterial-type flagellum organization
VCSRO96_0777	COG1580	Controls the rotational direction of flagella during chemotaxis
VCSRO96_0782	COG1987	bacterial-type flagellum assembly
VCSRO96_0783	COG1684	flagellar biosynthetic protein fliR
VCSRO96_0785	COG2840	Smr protein MutS2
VCSRO96_0786	COG2890	protein-(glutamine-N5) methyltransferase activity
VCSRO96_0787	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VCSRO96_0788	COG2860	membrane
VCSRO96_0789	COG3101	peptidyl-lysine hydroxylation
VCSRO96_0791	COG0431	NADPH-dependent FMN reductase
VCSRO96_0792	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VCSRO96_0792	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VCSRO96_0793	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCSRO96_0794	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO96_0795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCSRO96_0796	COG0735	belongs to the Fur family
VCSRO96_0798	COG0583	DNA-binding transcription factor activity
VCSRO96_0800	COG1346	cytolysis
VCSRO96_0801	COG3385	transposase activity
VCSRO96_0804	COG0596	Alpha beta hydrolase
VCSRO96_0805	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VCSRO96_0806	COG0033	Phosphoglucomutase
VCSRO96_0808	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VCSRO96_0809	COG0372	Belongs to the citrate synthase family
VCSRO96_0810	COG2009	succinate dehydrogenase
VCSRO96_0811	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VCSRO96_0812	COG1053	succinate dehydrogenase
VCSRO96_0814	COG0567	Dehydrogenase, E1 component
VCSRO96_0815	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCSRO96_0816	COG0045	succinate-CoA ligase (ADP-forming) activity
VCSRO96_0818	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VCSRO96_0819	COG1121	(ABC) transporter
VCSRO96_0820	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VCSRO96_0821	COG4977	sequence-specific DNA binding
VCSRO96_0822	COG1918	ferrous iron import across plasma membrane
VCSRO96_0826	COG0018	arginyl-trna synthetase
VCSRO96_0828	COG1025	Belongs to the peptidase M16 family
VCSRO96_0829	COG2062	phosphohistidine phosphatase, SixA
VCSRO96_0835	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VCSRO96_0836	COG0643	Histidine kinase
VCSRO96_0836	COG0784	Response regulator, receiver
VCSRO96_0836	COG2198	Histidine kinase
VCSRO96_0837	COG2201	protein-glutamate methylesterase activity
VCSRO96_0838	COG1192	Involved in chromosome partitioning
VCSRO96_0840	COG0835	chemotaxis
VCSRO96_0842	COG4133	protoheme IX ABC transporter activity
VCSRO96_0843	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCSRO96_0844	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCSRO96_0846	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VCSRO96_0847	COG1138	Cytochrome C-type biogenesis protein
VCSRO96_0848	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VCSRO96_0849	COG3088	subunit of a heme lyase
VCSRO96_0849	COG4235	cytochrome complex assembly
VCSRO96_0851	COG2853	Lipoprotein
VCSRO96_0855	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VCSRO96_0856	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCSRO96_0857	COG0123	including yeast histone deacetylase and acetoin utilization protein
VCSRO96_0861	COG3082	Protein of unknown function (DUF1414)
VCSRO96_0862	COG3081	Nucleoid-associated protein
VCSRO96_0864	COG1757	Na H antiporter
VCSRO96_0865	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCSRO96_0866	COG2095	MarC family integral membrane protein
VCSRO96_0867	COG1454	alcohol dehydrogenase
VCSRO96_0867	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO96_0869	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO96_0870	COG1530	ribonuclease E activity
VCSRO96_0871	COG0564	pseudouridine synthase activity
VCSRO96_0872	COG0424	maF-like protein
VCSRO96_0873	COG1399	metal-binding, possibly nucleic acid-binding protein
VCSRO96_0874	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VCSRO96_0875	COG0416	fatty acid biosynthetic process
VCSRO96_0876	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCSRO96_0878	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO96_0879	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VCSRO96_0880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCSRO96_0881	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCSRO96_0882	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VCSRO96_0883	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VCSRO96_0885	COG0084	hydrolase, TatD family'
VCSRO96_0886	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO96_0886	COG1263	PTS System
VCSRO96_0888	COG0733	neurotransmitter:sodium symporter activity
VCSRO96_0891	COG4667	esterase of the alpha-beta hydrolase superfamily
VCSRO96_0893	COG1940	carbohydrate kinase activity
VCSRO96_0894	COG0784	Response regulator, receiver
VCSRO96_0894	COG0835	chemotaxis
VCSRO96_0897	COG2226	methyltransferase
VCSRO96_0899	COG0676	glucose-6-phosphate 1-epimerase activity
VCSRO96_0900	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO96_0901	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO96_0903	COG3139	Protein of unknown function (DUF1315)
VCSRO96_0904	COG0252	asparaginase activity
VCSRO96_0905	COG0616	signal peptide processing
VCSRO96_0906	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCSRO96_0906	COG1902	pentaerythritol trinitrate reductase activity
VCSRO96_0907	COG0788	formyltetrahydrofolate deformylase activity
VCSRO96_0909	COG1199	ATP-dependent helicase activity
VCSRO96_0910	COG1214	PFAM Peptidase M22, glycoprotease
VCSRO96_0913	COG0596	Alpha beta hydrolase
VCSRO96_0914	COG0318	PFAM AMP-dependent synthetase and ligase
VCSRO96_0915	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VCSRO96_0919	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VCSRO96_0920	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VCSRO96_0921	COG0436	Aminotransferase
VCSRO96_0922	COG1169	isochorismate synthase
VCSRO96_0923	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VCSRO96_0924	COG0596	Alpha beta hydrolase
VCSRO96_0928	COG3135	benzoate transporter
VCSRO96_0929	COG1396	sequence-specific DNA binding
VCSRO96_0930	COG0840	transmembrane signaling receptor activity
VCSRO96_0937	COG3385	transposase activity
VCSRO96_0938	COG3015	lipoprotein NlpE involved in copper resistance
VCSRO96_0939	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VCSRO96_0940	COG2894	cell division
VCSRO96_0941	COG0850	regulation of cytokinetic process
VCSRO96_0942	COG3100	YcgL domain-containing protein
VCSRO96_0943	COG2951	lytic endotransglycosylase activity
VCSRO96_0945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO96_0946	COG3005	denitrification pathway
VCSRO96_0947	COG0243	molybdopterin cofactor binding
VCSRO96_0951	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO96_0953	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VCSRO96_0960	COG4589	Belongs to the CDS family
VCSRO96_0962	COG3300	MHYT domain
VCSRO96_0962	COG5001	Diguanylate cyclase
VCSRO96_0965	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VCSRO96_0966	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCSRO96_0967	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCSRO96_0968	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCSRO96_0970	COG4191	Histidine kinase
VCSRO96_0971	COG0544	peptidyl-prolyl cis-trans isomerase activity
VCSRO96_0973	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VCSRO96_0974	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VCSRO96_0975	COG0776	regulation of translation
VCSRO96_0976	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO96_0977	COG1555	photosystem II stabilization
VCSRO96_0978	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VCSRO96_0979	COG0539	negative regulation of cytoplasmic translation
VCSRO96_0980	COG0776	regulation of translation
VCSRO96_0981	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VCSRO96_0982	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VCSRO96_0986	COG0583	DNA-binding transcription factor activity
VCSRO96_0988	COG0686	Belongs to the AlaDH PNT family
VCSRO96_0990	COG1674	ftsk spoiiie
VCSRO96_0991	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VCSRO96_0992	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCSRO96_0993	COG2186	Transcriptional regulator
VCSRO96_0997	COG0537	adenosine 5'-monophosphoramidase activity
VCSRO96_1002	COG3150	esterase
VCSRO96_1003	COG1252	NADH dehydrogenase
VCSRO96_1007	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VCSRO96_1009	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO96_1010	COG1136	(ABC) transporter
VCSRO96_1011	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO96_1013	COG0658	competence protein
VCSRO96_1013	COG2333	competence protein COMEC
VCSRO96_1014	COG1132	(ABC) transporter
VCSRO96_1015	COG1663	tetraacyldisaccharide 4'-kinase activity
VCSRO96_1016	COG2835	tetraacyldisaccharide 4'-kinase activity
VCSRO96_1017	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VCSRO96_1018	COG2719	SpoVR family
VCSRO96_1019	COG2718	Belongs to the UPF0229 family
VCSRO96_1020	COG2766	serine protein kinase
VCSRO96_1021	COG3013	Belongs to the UPF0304 family
VCSRO96_1023	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VCSRO96_1024	COG0840	transmembrane signaling receptor activity
VCSRO96_1026	COG1882	Formate acetyltransferase
VCSRO96_1032	COG4160	amino acid transport
VCSRO96_1033	COG0708	Exodeoxyribonuclease III
VCSRO96_1034	COG0840	transmembrane signaling receptor activity
VCSRO96_1036	COG3923	Primosomal replication protein n
VCSRO96_1037	COG0730	response to heat
VCSRO96_1038	COG1199	ATP-dependent helicase activity
VCSRO96_1039	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCSRO96_1040	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCSRO96_1041	COG3012	SEC-C Motif Domain Protein
VCSRO96_1042	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCSRO96_1043	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO96_1044	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCSRO96_1045	COG0215	cysteine-tRNA ligase activity
VCSRO96_1046	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VCSRO96_1047	COG0632	four-way junction helicase activity
VCSRO96_1050	COG1271	oxidase subunit
VCSRO96_1051	COG1294	oxidase, subunit
VCSRO96_1052	COG4890	Cyd operon protein YbgT
VCSRO96_1053	COG0824	Thioesterase
VCSRO96_1054	COG0811	peptide transport
VCSRO96_1057	COG0823	Involved in the tonB-independent uptake of proteins
VCSRO96_1058	COG2885	chlorophyll binding
VCSRO96_1060	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VCSRO96_1062	COG5002	protein histidine kinase activity
VCSRO96_1062	COG0784	Response regulator, receiver
VCSRO96_1064	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO96_1065	COG3284	Transcriptional regulator
VCSRO96_1066	COG4628	conserved protein (DUF2132)
VCSRO96_1068	COG0415	Belongs to the DNA photolyase family
VCSRO96_1074	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO96_1076	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCSRO96_1076	COG3008	intermembrane lipid transfer
VCSRO96_1077	COG2995	paraquat-inducible protein a
VCSRO96_1078	COG1309	transcriptional regulator
VCSRO96_1079	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO96_1084	COG1960	acyl-CoA dehydrogenase activity
VCSRO96_1085	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCSRO96_1086	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VCSRO96_1087	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
VCSRO96_1088	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VCSRO96_1091	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCSRO96_1092	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCSRO96_1093	COG0297	glycogen (starch) synthase activity
VCSRO96_1097	COG3070	regulator of competence-specific genes
VCSRO96_1098	COG1609	Transcriptional regulator
VCSRO96_1099	COG3381	protein complex oligomerization
VCSRO96_1100	COG0745	RESPONSE REGULATOR receiver
VCSRO96_1101	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCSRO96_1102	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCSRO96_1103	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VCSRO96_1104	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VCSRO96_1108	COG1032	radical SAM domain protein
VCSRO96_1110	COG0612	Peptidase, M16
VCSRO96_1113	COG0583	DNA-binding transcription factor activity
VCSRO96_1114	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VCSRO96_1116	COG2350	Protein conserved in bacteria
VCSRO96_1117	COG1607	acyl-coa hydrolase
VCSRO96_1120	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCSRO96_1121	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCSRO96_1123	COG2116	formate transmembrane transporter activity
VCSRO96_1124	COG4459	periplasmic nitrate reductase
VCSRO96_1125	COG3005	denitrification pathway
VCSRO96_1126	COG0243	molybdopterin cofactor binding
VCSRO96_1129	COG1227	inorganic diphosphatase activity
VCSRO96_1132	COG4172	Belongs to the ABC transporter superfamily
VCSRO96_1135	COG4168	peptide transport system, permease
VCSRO96_1137	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VCSRO96_1138	COG1842	Phage shock protein A
VCSRO96_1141	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO96_1143	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO96_1145	COG2818	Glycosylase
VCSRO96_1146	COG0589	response to stress
VCSRO96_1148	COG0626	cystathionine gamma-synthase activity
VCSRO96_1150	COG0733	neurotransmitter:sodium symporter activity
VCSRO96_1151	COG0564	pseudouridine synthase activity
VCSRO96_1152	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VCSRO96_1153	COG4136	ATPase activity
VCSRO96_1154	COG4135	transport system, permease component
VCSRO96_1155	COG4134	Bacterial extracellular solute-binding protein
VCSRO96_1157	COG3313	Fe-S protein
VCSRO96_1159	COG0842	Transport permease protein
VCSRO96_1160	COG1131	(ABC) transporter
VCSRO96_1161	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO96_1162	COG0814	amino acid
VCSRO96_1165	COG2239	Acts as a magnesium transporter
VCSRO96_1166	COG0784	Response regulator, receiver
VCSRO96_1166	COG2205	protein histidine kinase activity
VCSRO96_1167	COG1716	ATPase activity
VCSRO96_1167	COG5001	Diguanylate cyclase
VCSRO96_1170	COG4934	collagen metabolic process
VCSRO96_1176	COG0840	transmembrane signaling receptor activity
VCSRO96_1178	COG3706	GGDEF domain
VCSRO96_1178	COG5001	Diguanylate cyclase
VCSRO96_1178	COG2203	Gaf domain
VCSRO96_1178	COG4251	negative regulation of phosphorylation
VCSRO96_1179	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VCSRO96_1183	COG1061	Type III restriction enzyme res subunit
VCSRO96_1184	COG1187	pseudouridine synthase activity
VCSRO96_1185	COG2814	Major facilitator Superfamily
VCSRO96_1187	COG0702	epimerase
VCSRO96_1188	COG0534	Mate efflux family protein
VCSRO96_1189	COG4181	ATPase activity
VCSRO96_1190	COG0577	efflux transmembrane transporter activity
VCSRO96_1192	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCSRO96_1194	COG1748	Saccharopine dehydrogenase
VCSRO96_1197	COG1538	Outer membrane efflux protein
VCSRO96_1201	COG0583	DNA-binding transcription factor activity
VCSRO96_1203	COG1451	nucleotide metabolic process
VCSRO96_1206	COG3063	Type IV pilus biogenesis stability protein PilW
VCSRO96_1207	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VCSRO96_1211	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO96_1214	COG3290	protein histidine kinase activity
VCSRO96_1215	COG4565	transcriptional regulatory protein
VCSRO96_1217	COG0835	chemotaxis
VCSRO96_1217	COG0784	Response regulator, receiver
VCSRO96_1225	COG1085	galactose-1-phosphate uridylyltransferase
VCSRO96_1226	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VCSRO96_1227	COG2017	converts alpha-aldose to the beta-anomer
VCSRO96_1229	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO96_1231	COG3527	Alpha-acetolactate decarboxylase
VCSRO96_1234	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCSRO96_1236	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCSRO96_1239	COG3097	Belongs to the UPF0267 family
VCSRO96_1244	COG1271	oxidase subunit
VCSRO96_1245	COG1294	oxidase, subunit
VCSRO96_1246	COG1136	(ABC) transporter
VCSRO96_1246	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO96_1247	COG0577	efflux transmembrane transporter activity
VCSRO96_1247	COG1136	(ABC) transporter
VCSRO96_1248	COG0577	efflux transmembrane transporter activity
VCSRO96_1248	COG1136	(ABC) transporter
VCSRO96_1253	COG2723	6-phospho-beta-galactosidase activity
VCSRO96_1254	COG1609	Transcriptional regulator
VCSRO96_1255	COG0251	oxidation-reduction process
VCSRO96_1256	COG2731	YhcH YjgK YiaL family protein
VCSRO96_1257	COG0584	glycerophosphoryl diester phosphodiesterase
VCSRO96_1258	COG1349	DNA-binding transcription factor activity
VCSRO96_1259	COG3842	ATPase activity
VCSRO96_1260	COG0395	ABC-type sugar transport system, permease component
VCSRO96_1261	COG1175	transmembrane transport
VCSRO96_1264	COG0811	peptide transport
VCSRO96_1265	COG0811	peptide transport
VCSRO96_1266	COG0848	biopolymer transport protein
VCSRO96_1267	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCSRO96_1269	COG1793	dna ligase
VCSRO96_1271	COG0534	Mate efflux family protein
VCSRO96_1273	COG3001	Fructosamine kinase
VCSRO96_1275	COG0791	NLP P60 protein
VCSRO96_1276	COG0840	transmembrane signaling receptor activity
VCSRO96_1278	COG3148	PFAM DTW domain containing protein
VCSRO96_1279	COG1940	carbohydrate kinase activity
VCSRO96_1282	COG0746	molybdenum cofactor guanylyltransferase activity
VCSRO96_1283	COG3842	ATPase activity
VCSRO96_1284	COG4662	Binding-protein-dependent transport system inner membrane component
VCSRO96_1286	COG2204	response regulator
VCSRO96_1287	COG3852	Histidine kinase
VCSRO96_1288	COG0488	(ABC) transporter
VCSRO96_1289	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VCSRO96_1295	COG3383	formate dehydrogenase (NAD+) activity
VCSRO96_1295	COG3383	formate dehydrogenase (NAD+) activity
VCSRO96_1296	COG0437	4 iron, 4 sulfur cluster binding
VCSRO96_1297	COG0437	4 iron, 4 sulfur cluster binding
VCSRO96_1300	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VCSRO96_1301	COG1666	GTP binding
VCSRO96_1302	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO96_1305	COG2996	Protein conserved in bacteria
VCSRO96_1307	COG3008	intermembrane lipid transfer
VCSRO96_1308	COG2995	paraquat-inducible protein a
VCSRO96_1309	COG1132	(ABC) transporter
VCSRO96_1310	COG1956	GAF domain-containing protein
VCSRO96_1311	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VCSRO96_1315	COG0308	aminopeptidase N
VCSRO96_1317	COG0167	dihydroorotate dehydrogenase activity
VCSRO96_1319	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCSRO96_1319	COG0116	Belongs to the methyltransferase superfamily
VCSRO96_1321	COG0488	(ABC) transporter
VCSRO96_1324	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCSRO96_1325	COG1067	ATP-dependent peptidase activity
VCSRO96_1326	COG3120	sequence-specific DNA binding
VCSRO96_1353	COG3064	Membrane
VCSRO96_1353	COG1073	alpha beta
VCSRO96_1353	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VCSRO96_1354	COG2994	toxin metabolic process
VCSRO96_1359	COG0784	Response regulator, receiver
VCSRO96_1359	COG2205	protein histidine kinase activity
VCSRO96_1362	COG3278	Belongs to the heme-copper respiratory oxidase family
VCSRO96_1365	COG2010	Cytochrome c
VCSRO96_1367	COG2217	Heavy metal translocating P-type atpase
VCSRO96_1370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VCSRO96_1371	COG0589	response to stress
VCSRO96_1372	COG0037	tRNA processing
VCSRO96_1376	COG3842	ATPase activity
VCSRO96_1378	COG1177	transmembrane transport
VCSRO96_1380	COG3385	transposase activity
VCSRO96_1381	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCSRO96_1384	COG1115	amino acid carrier protein
VCSRO96_1385	COG1280	lysine exporter protein (LysE YggA)
VCSRO96_1389	COG3501	Rhs element vgr protein
VCSRO96_1391	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VCSRO96_1393	COG2814	Major facilitator Superfamily
VCSRO96_1394	COG1566	PFAM secretion protein HlyD family protein
VCSRO96_1395	COG1538	Outer membrane efflux protein
VCSRO96_1397	COG0513	Belongs to the DEAD box helicase family
VCSRO96_1401	COG0415	Belongs to the DNA photolyase family
VCSRO96_1402	COG0477	Major facilitator Superfamily
VCSRO96_1403	COG0583	DNA-binding transcription factor activity
VCSRO96_1404	COG0095	Lipoate-protein ligase
VCSRO96_1405	COG0443	Heat shock 70 kDa protein
VCSRO96_1407	COG1643	Atp-dependent helicase
VCSRO96_1414	COG0443	Heat shock 70 kDa protein
VCSRO96_1415	COG0443	Heat shock 70 kDa protein
VCSRO96_1416	COG3706	GGDEF domain
VCSRO96_1422	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VCSRO96_1423	COG0602	queuosine metabolic process
VCSRO96_1425	COG0561	phosphatase activity
VCSRO96_1427	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO96_1428	COG4597	amino acid ABC transporter
VCSRO96_1429	COG0765	amino acid transport
VCSRO96_1430	COG1126	abc transporter atp-binding protein
VCSRO96_1431	COG0670	Belongs to the BI1 family
VCSRO96_1432	COG2920	part of a sulfur-relay system
VCSRO96_1433	COG1254	Belongs to the acylphosphatase family
VCSRO96_1434	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCSRO96_1435	COG3706	GGDEF domain
VCSRO96_1437	COG2205	protein histidine kinase activity
VCSRO96_1437	COG3437	response regulator, receiver
VCSRO96_1437	COG3850	Histidine kinase
VCSRO96_1437	COG4999	Histidine kinase
VCSRO96_1438	COG3437	response regulator, receiver
VCSRO96_1439	COG0625	glutathione transferase activity
VCSRO96_1441	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VCSRO96_1443	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO96_1449	COG0372	Belongs to the citrate synthase family
VCSRO96_1450	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VCSRO96_1458	COG1129	ABC transporter
VCSRO96_1463	COG0745	RESPONSE REGULATOR receiver
VCSRO96_1464	COG2205	protein histidine kinase activity
VCSRO96_1465	COG3713	MltA-interacting MipA family protein
VCSRO96_1466	COG2990	Protein conserved in bacteria
VCSRO96_1468	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO96_1468	COG4191	Histidine kinase
VCSRO96_1469	COG0471	metal ion transport
VCSRO96_1471	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCSRO96_1474	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO96_1476	COG3768	UPF0283 membrane protein
VCSRO96_1477	COG3106	COG3106 Predicted ATPase
VCSRO96_1480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCSRO96_1481	COG0494	nUDIX hydrolase
VCSRO96_1482	COG0814	amino acid
VCSRO96_1483	COG1760	l-serine dehydratase
VCSRO96_1484	COG3385	transposase activity
VCSRO96_1485	COG0720	synthase
VCSRO96_1488	COG0720	synthase
VCSRO96_1489	COG0840	transmembrane signaling receptor activity
VCSRO96_1490	COG0017	Asparaginyl-tRNA synthetase
VCSRO96_1491	COG0351	phosphomethylpyrimidine kinase
VCSRO96_1492	COG2770	Histidine kinase
VCSRO96_1492	COG3437	response regulator, receiver
VCSRO96_1493	COG1448	Aminotransferase
VCSRO96_1496	COG0840	transmembrane signaling receptor activity
VCSRO96_1497	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
VCSRO96_1498	COG2943	transferase activity, transferring hexosyl groups
VCSRO96_1499	COG1609	Transcriptional regulator
VCSRO96_1500	COG3394	polysaccharide catabolic process
VCSRO96_1501	COG1486	melibiose metabolic process
VCSRO96_1502	COG1447	Phosphotransferase system cellobiose-specific component IIA
VCSRO96_1504	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VCSRO96_1505	COG0726	polysaccharide deacetylase
VCSRO96_1506	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VCSRO96_1507	COG1846	Transcriptional regulator
VCSRO96_1512	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCSRO96_1515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCSRO96_1516	COG3108	Peptidase M15
VCSRO96_1522	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VCSRO96_1524	COG2814	Major facilitator Superfamily
VCSRO96_1526	COG1054	Belongs to the UPF0176 family
VCSRO96_1528	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCSRO96_1529	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCSRO96_1530	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCSRO96_1539	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
VCSRO96_1540	COG4139	cobalamin transport
VCSRO96_1541	COG2988	succinylglutamate desuccinylase activity
VCSRO96_1545	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VCSRO96_1546	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VCSRO96_1547	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO96_1548	COG1823	symporter activity
VCSRO96_1549	COG2925	Exonuclease
VCSRO96_1550	COG1380	Effector of murein hydrolase LrgA
VCSRO96_1551	COG1346	cytolysis
VCSRO96_1558	COG0776	regulation of translation
VCSRO96_1559	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO96_1559	COG0072	phenylalanine-tRNA ligase activity
VCSRO96_1560	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VCSRO96_1568	COG0322	excinuclease ABC activity
VCSRO96_1569	COG2197	response regulator
VCSRO96_1570	COG0417	DNA replication proofreading
VCSRO96_1571	COG5001	Diguanylate cyclase
VCSRO96_1573	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCSRO96_1574	COG3099	Belongs to the UPF0263 family
VCSRO96_1577	COG1228	amidohydrolase
VCSRO96_1578	COG0010	Belongs to the arginase family
VCSRO96_1579	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VCSRO96_1580	COG2986	histidine ammonia-lyase
VCSRO96_1585	COG0277	FAD linked oxidase domain protein
VCSRO96_1585	COG0247	lactate metabolic process
VCSRO96_1588	COG2885	chlorophyll binding
VCSRO96_1592	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VCSRO96_1594	COG0281	malic enzyme
VCSRO96_1596	COG2949	membrane
VCSRO96_1597	COG3706	GGDEF domain
VCSRO96_1598	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCSRO96_1600	COG0492	ferredoxin-NADP+ reductase activity
VCSRO96_1601	COG4988	ABC transporter
VCSRO96_1602	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VCSRO96_1603	COG1187	pseudouridine synthase activity
VCSRO96_1604	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO96_1605	COG0613	PHP domain protein
VCSRO96_1606	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCSRO96_1607	COG0512	Glutamine amidotransferase of anthranilate synthase
VCSRO96_1608	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VCSRO96_1609	COG0134	indole-3-glycerol-phosphate synthase activity
VCSRO96_1609	COG0135	phosphoribosylanthranilate isomerase activity
VCSRO96_1610	COG0133	tryptophan synthase activity
VCSRO96_1611	COG0159	tryptophan synthase activity
VCSRO96_1613	COG1435	thymidine kinase activity
VCSRO96_1614	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VCSRO96_1615	COG1801	Protein of unknown function DUF72
VCSRO96_1616	COG4106	trans-aconitate 2-methyltransferase activity
VCSRO96_1617	COG0500	methyltransferase
VCSRO96_1618	COG4067	protein conserved in archaea
VCSRO96_1618	COG0189	ligase activity
VCSRO96_1621	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VCSRO96_1623	COG3852	Histidine kinase
VCSRO96_1626	COG3070	regulator of competence-specific genes
VCSRO96_1628	COG2431	L-lysine efflux transmembrane transporter activity
VCSRO96_1630	COG0076	glutamate decarboxylase activity
VCSRO96_1631	COG1737	Transcriptional regulator
VCSRO96_1632	COG1454	alcohol dehydrogenase
VCSRO96_1632	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO96_1633	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCSRO96_1634	COG3385	transposase activity
VCSRO96_1635	COG2985	domain, Protein
VCSRO96_1635	COG3273	potassium ion transport
VCSRO96_1636	COG0542	response to heat
VCSRO96_1637	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VCSRO96_1638	COG1278	Cold shock
VCSRO96_1640	COG1187	pseudouridine synthase activity
VCSRO96_1641	COG0140	phosphoribosyl-ATP diphosphatase activity
VCSRO96_1641	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VCSRO96_1642	COG0107	imidazoleglycerol-phosphate synthase activity
VCSRO96_1643	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VCSRO96_1644	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VCSRO96_1645	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCSRO96_1645	COG0131	Imidazoleglycerol-phosphate dehydratase
VCSRO96_1646	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VCSRO96_1647	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VCSRO96_1648	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VCSRO96_1649	COG1757	Na H antiporter
VCSRO96_1650	COG2916	Histone family protein nucleoid-structuring protein H-NS
VCSRO96_1651	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO96_1652	COG0482	sulfurtransferase activity
VCSRO96_1653	COG2915	High frequency lysogenization protein hflD homolog
VCSRO96_1654	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VCSRO96_1656	COG2268	Band 7 protein
VCSRO96_1658	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VCSRO96_1661	COG0300	oxidoreductase activity
VCSRO96_1663	COG0501	Belongs to the peptidase M48B family
VCSRO96_1665	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VCSRO96_1666	COG2226	methyltransferase
VCSRO96_1667	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO96_1668	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCSRO96_1669	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VCSRO96_1670	COG2801	Transposase and inactivated derivatives
VCSRO96_1673	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VCSRO96_1674	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VCSRO96_1675	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VCSRO96_1676	COG0653	protein targeting
VCSRO96_1677	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO96_1678	COG2199	diguanylate cyclase activity
VCSRO96_1678	COG2203	Gaf domain
VCSRO96_1680	COG4120	Belongs to the binding-protein-dependent transport system permease family
VCSRO96_1683	COG4628	conserved protein (DUF2132)
VCSRO96_1684	COG3092	negative regulation of chromosome organization
VCSRO96_1685	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCSRO96_1686	COG0280	phosphate acetyltransferase
VCSRO96_1686	COG0857	belongs to the CobB CobQ family
VCSRO96_1687	COG0435	Glutathione S-transferase
VCSRO96_1688	COG4608	Belongs to the ABC transporter superfamily
VCSRO96_1689	COG0444	Belongs to the ABC transporter superfamily
VCSRO96_1690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO96_1691	COG0601	transmembrane transport
VCSRO96_1695	COG2204	response regulator
VCSRO96_1696	COG5001	Diguanylate cyclase
VCSRO96_1696	COG3300	MHYT domain
VCSRO96_1697	COG4191	Histidine kinase
VCSRO96_1698	COG5002	protein histidine kinase activity
VCSRO96_1700	COG2201	protein-glutamate methylesterase activity
VCSRO96_1703	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO96_1706	COG1881	PFAM PEBP family protein
VCSRO96_1711	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO96_1712	COG0640	Transcriptional regulator
VCSRO96_1713	COG3706	GGDEF domain
VCSRO96_1716	COG1946	Acyl-CoA thioesterase
VCSRO96_1717	COG1522	sequence-specific DNA binding
VCSRO96_1719	COG0616	signal peptide processing
VCSRO96_1720	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO96_1722	COG2983	Belongs to the UPF0260 family
VCSRO96_1724	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VCSRO96_1725	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VCSRO96_1727	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VCSRO96_1728	COG2832	Protein of unknown function (DUF454)
VCSRO96_1730	COG0745	RESPONSE REGULATOR receiver
VCSRO96_1731	COG0583	DNA-binding transcription factor activity
VCSRO96_1732	COG0778	Nitroreductase
VCSRO96_1733	COG1024	Enoyl-CoA hydratase
VCSRO96_1733	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCSRO96_1734	COG0183	Belongs to the thiolase family
VCSRO96_1737	COG2067	long-chain fatty acid transport protein
VCSRO96_1739	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VCSRO96_1740	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VCSRO96_1741	COG2982	Protein involved in outer membrane biogenesis
VCSRO96_1742	COG0572	uridine kinase
VCSRO96_1743	COG0489	protein tyrosine kinase activity
VCSRO96_1744	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO96_1744	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO96_1746	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO96_1748	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
VCSRO96_1748	COG0617	tRNA 3'-terminal CCA addition
VCSRO96_1748	COG0517	IMP dehydrogenase activity
VCSRO96_1749	COG2199	diguanylate cyclase activity
VCSRO96_1750	COG0314	molybdopterin synthase activity
VCSRO96_1751	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VCSRO96_1752	COG0315	cyclic pyranopterin monophosphate synthase activity
VCSRO96_1753	COG0521	Mo-molybdopterin cofactor biosynthetic process
VCSRO96_1754	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VCSRO96_1755	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VCSRO96_1756	COG2198	Histidine kinase
VCSRO96_1757	COG2204	response regulator
VCSRO96_1758	COG0556	nucleotide-excision repair
VCSRO96_1760	COG4657	Part of a membrane complex involved in electron transport
VCSRO96_1761	COG2878	Part of a membrane complex involved in electron transport
VCSRO96_1762	COG4656	Part of a membrane complex involved in electron transport
VCSRO96_1765	COG4660	Part of a membrane complex involved in electron transport
VCSRO96_1766	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VCSRO96_1767	COG0346	lactoylglutathione lyase activity
VCSRO96_1770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VCSRO96_1771	COG2056	Na+-H+ antiporter family
VCSRO96_1772	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VCSRO96_1773	COG1286	toxin biosynthetic process
VCSRO96_1774	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VCSRO96_1775	COG0285	dihydrofolate synthase activity
VCSRO96_1776	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VCSRO96_1777	COG0101	tRNA pseudouridine synthase activity
VCSRO96_1780	COG2190	(PTS) system
VCSRO96_1780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO96_1780	COG1263	PTS System
VCSRO96_1781	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VCSRO96_1782	COG1940	carbohydrate kinase activity
VCSRO96_1782	COG1846	Transcriptional regulator
VCSRO96_1783	COG4651	solute:proton antiporter activity
VCSRO96_1783	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCSRO96_1784	COG0367	asparagine synthase
VCSRO96_1787	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VCSRO96_1788	COG0563	adenylate kinase activity
VCSRO96_1789	COG0326	Molecular chaperone. Has ATPase activity
VCSRO96_1790	COG3710	Transcriptional regulator
VCSRO96_1793	COG0622	Phosphoesterase
VCSRO96_1794	COG1090	epimerase
VCSRO96_1795	COG0300	oxidoreductase activity
VCSRO96_1796	COG3118	belongs to the thioredoxin family
VCSRO96_1798	COG0330	HflC and HflK could
VCSRO96_1799	COG1585	Membrane protein implicated in regulation of membrane protease activity
VCSRO96_1800	COG0789	Transcriptional regulator
VCSRO96_1803	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VCSRO96_1804	COG3115	cell septum assembly
VCSRO96_1805	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VCSRO96_1806	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VCSRO96_1807	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO96_1809	COG2190	(PTS) system
VCSRO96_1810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO96_1811	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCSRO96_1812	COG1702	phosphate starvation-inducible protein PhoH
VCSRO96_1813	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VCSRO96_1814	COG4535	Mg2 and Co2 transporter CorC
VCSRO96_1815	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VCSRO96_1816	COG2888	peptidyl-tyrosine sulfation
VCSRO96_1817	COG0495	leucyl-tRNA aminoacylation
VCSRO96_1818	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VCSRO96_1819	COG1466	dna polymerase III delta subunit
VCSRO96_1820	COG0799	negative regulation of ribosome biogenesis
VCSRO96_1821	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VCSRO96_1822	COG0768	penicillin binding
VCSRO96_1823	COG0772	Belongs to the SEDS family
VCSRO96_1824	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCSRO96_1825	COG1686	Belongs to the peptidase S11 family
VCSRO96_1826	COG2921	Belongs to the UPF0250 family
VCSRO96_1827	COG0321	lipoyl(octanoyl) transferase activity
VCSRO96_1828	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VCSRO96_1830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCSRO96_1835	COG1596	polysaccharide export
VCSRO96_1837	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCSRO96_1840	COG3385	transposase activity
VCSRO96_1845	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
VCSRO96_1847	COG0438	transferase activity, transferring glycosyl groups
VCSRO96_1849	COG1045	serine acetyltransferase
VCSRO96_1854	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VCSRO96_1855	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VCSRO96_1858	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO96_1864	COG0366	Alpha amylase catalytic
VCSRO96_1865	COG1263	PTS System
VCSRO96_1865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO96_1866	COG1609	Transcriptional regulator
VCSRO96_1867	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCSRO96_1868	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VCSRO96_1869	COG2011	ABC-type metal ion transport system permease component
VCSRO96_1870	COG1464	Belongs to the NlpA lipoprotein family
VCSRO96_1871	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VCSRO96_1873	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCSRO96_1873	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCSRO96_1876	COG1611	Belongs to the LOG family
VCSRO96_1877	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO96_1878	COG2363	Small membrane protein
VCSRO96_1879	COG0583	DNA-binding transcription factor activity
VCSRO96_1880	COG0301	tRNA thio-modification
VCSRO96_1880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO96_1882	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VCSRO96_1883	COG1722	exodeoxyribonuclease VII activity
VCSRO96_1884	COG0142	geranyltranstransferase activity
VCSRO96_1885	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VCSRO96_1886	COG0564	pseudouridine synthase activity
VCSRO96_1887	COG3098	single-species biofilm formation
VCSRO96_1890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO96_1892	COG1671	Belongs to the UPF0178 family
VCSRO96_1893	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCSRO96_1894	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCSRO96_1895	COG0254	rRNA binding
VCSRO96_1896	COG1720	tRNA m6t6A37 methyltransferase activity
VCSRO96_1897	COG0442	prolyl-tRNA aminoacylation
VCSRO96_1901	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VCSRO96_1901	COG0047	phosphoribosylformylglycinamidine synthase activity
VCSRO96_1902	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VCSRO96_1905	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCSRO96_1911	COG0484	heat shock protein binding
VCSRO96_1912	COG0443	Heat shock 70 kDa protein
VCSRO96_1913	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VCSRO96_1914	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VCSRO96_1915	COG0497	DNA recombination
VCSRO96_1916	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO96_1917	COG2914	Belongs to the UPF0125 (RnfH) family
VCSRO96_1918	COG2867	negative regulation of translational initiation
VCSRO96_1919	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VCSRO96_1921	COG0582	viral genome integration into host DNA
VCSRO96_1927	COG1518	maintenance of DNA repeat elements
VCSRO96_1930	COG3501	Rhs element vgr protein
VCSRO96_1946	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VCSRO96_1947	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VCSRO96_1948	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCSRO96_1952	COG3051	citrate lyase alpha subunit
VCSRO96_1953	COG2301	Belongs to the HpcH HpaI aldolase family
VCSRO96_1954	COG3052	prosthetic group binding
VCSRO96_1955	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
VCSRO96_1957	COG3630	sodium ion export across plasma membrane
VCSRO96_1958	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO96_1958	COG5016	pyruvate
VCSRO96_1959	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCSRO96_1961	COG4565	transcriptional regulatory protein
VCSRO96_1964	COG0583	DNA-binding transcription factor activity
VCSRO96_1966	COG1115	amino acid carrier protein
VCSRO96_1967	COG2977	Belongs to the P-Pant transferase superfamily
VCSRO96_1968	COG1120	ATPase activity
VCSRO96_1969	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO96_1970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO96_1971	COG4592	Periplasmic binding protein
VCSRO96_1973	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO96_1974	COG1169	isochorismate synthase
VCSRO96_1975	COG1021	2,3-dihydroxybenzoate-AMP ligase
VCSRO96_1976	COG1535	isochorismatase
VCSRO96_1976	COG3433	isochorismatase activity
VCSRO96_1977	COG1584	GPR1 FUN34 yaaH family protein
VCSRO96_1979	COG0519	Catalyzes the synthesis of GMP from XMP
VCSRO96_1979	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VCSRO96_1980	COG0516	GMP reductase activity
VCSRO96_1980	COG0517	IMP dehydrogenase activity
VCSRO96_1981	COG1570	exodeoxyribonuclease VII activity
VCSRO96_1984	COG1160	GTP binding
VCSRO96_1985	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO96_1986	COG2976	Protein conserved in bacteria
VCSRO96_1987	COG0124	histidyl-tRNA synthetase
VCSRO96_1988	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VCSRO96_1991	COG0105	UTP biosynthetic process
VCSRO96_1992	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCSRO96_1993	COG2975	iron-sulfur cluster assembly
VCSRO96_1994	COG0633	Ferredoxin
VCSRO96_1998	COG0822	iron-sulfur transferase activity
VCSRO96_1999	COG1104	cysteine desulfurase activity
VCSRO96_2000	COG1959	2 iron, 2 sulfur cluster binding
VCSRO96_2002	COG0483	inositol monophosphate 1-phosphatase activity
VCSRO96_2003	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO96_2004	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO96_2005	COG1862	Preprotein translocase
VCSRO96_2007	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
VCSRO96_2008	COG0517	IMP dehydrogenase activity
VCSRO96_2010	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VCSRO96_2011	COG0583	DNA-binding transcription factor activity
VCSRO96_2012	COG0450	alkyl hydroperoxide reductase
VCSRO96_2013	COG3142	Participates in the control of copper homeostasis
VCSRO96_2016	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCSRO96_2017	COG0581	inorganic phosphate transmembrane transporter activity
VCSRO96_2019	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VCSRO96_2020	COG0248	Ppx GppA phosphatase
VCSRO96_2022	COG5002	protein histidine kinase activity
VCSRO96_2023	COG0745	RESPONSE REGULATOR receiver
VCSRO96_2025	COG0826	peptidase U32
VCSRO96_2026	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCSRO96_2034	COG0542	response to heat
VCSRO96_2036	COG0564	pseudouridine synthase activity
VCSRO96_2037	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO96_2038	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCSRO96_2039	COG1605	Chorismate mutase
VCSRO96_2039	COG0077	Prephenate dehydratase
VCSRO96_2040	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCSRO96_2041	COG5001	Diguanylate cyclase
VCSRO96_2043	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VCSRO96_2045	COG0488	(ABC) transporter
VCSRO96_2047	COG1605	Chorismate mutase
VCSRO96_2047	COG0287	Prephenate dehydrogenase
VCSRO96_2048	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO96_2049	COG3275	phosphorelay sensor kinase activity
VCSRO96_2050	COG3279	Response regulator of the LytR AlgR family
VCSRO96_2052	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VCSRO96_2053	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCSRO96_2055	COG1966	Carbon starvation protein
VCSRO96_2056	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VCSRO96_2057	COG1047	Peptidyl-prolyl cis-trans
VCSRO96_2058	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VCSRO96_2060	COG0196	riboflavin kinase activity
VCSRO96_2061	COG0728	peptidoglycan biosynthetic process
VCSRO96_2062	COG0268	Binds directly to 16S ribosomal RNA
VCSRO96_2063	COG0640	Transcriptional regulator
VCSRO96_2064	COG0583	DNA-binding transcription factor activity
VCSRO96_2065	COG1283	sodium-dependent phosphate transmembrane transporter activity
VCSRO96_2067	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VCSRO96_2068	COG0730	response to heat
VCSRO96_2069	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
VCSRO96_2070	COG0494	nUDIX hydrolase
VCSRO96_2072	COG0667	Aldo Keto reductase
VCSRO96_2075	COG2204	response regulator
VCSRO96_2076	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VCSRO96_2077	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VCSRO96_2080	COG0513	Belongs to the DEAD box helicase family
VCSRO96_2085	COG3153	acetyltransferase
VCSRO96_2086	COG3154	lipid carrier protein
VCSRO96_2089	COG0826	peptidase U32
VCSRO96_2090	COG0826	peptidase U32
VCSRO96_2095	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VCSRO96_2097	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VCSRO96_2098	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VCSRO96_2099	COG0195	Participates in both transcription termination and antitermination
VCSRO96_2100	COG0779	Required for maturation of 30S ribosomal subunits
VCSRO96_2103	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCSRO96_2106	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VCSRO96_2107	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VCSRO96_2108	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VCSRO96_2109	COG1534	Rna-binding protein
VCSRO96_2110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO96_2111	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCSRO96_2112	COG2027	D-alanyl-D-alanine carboxypeptidase
VCSRO96_2113	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCSRO96_2114	COG0739	heme binding
VCSRO96_2117	COG0316	Belongs to the HesB IscA family
VCSRO96_2118	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VCSRO96_2120	COG0628	permease
VCSRO96_2121	COG2813	Specifically methylates the guanine in position
VCSRO96_2122	COG0784	Response regulator, receiver
VCSRO96_2122	COG2205	protein histidine kinase activity
VCSRO96_2123	COG2801	Transposase and inactivated derivatives
VCSRO96_2125	COG0747	negative chemotaxis
VCSRO96_2126	COG0601	transmembrane transport
VCSRO96_2127	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO96_2128	COG0444	Belongs to the ABC transporter superfamily
VCSRO96_2129	COG4608	Belongs to the ABC transporter superfamily
VCSRO96_2131	COG2971	BadF BadG BcrA BcrD
VCSRO96_2135	COG3842	ATPase activity
VCSRO96_2137	COG1840	ABC-type Fe3 transport system, periplasmic component
VCSRO96_2138	COG0004	ammonium transporteR
VCSRO96_2139	COG0347	Belongs to the P(II) protein family
VCSRO96_2140	COG3112	Uncharacterised protein family (UPF0231)
VCSRO96_2141	COG1049	propionate catabolic process, 2-methylcitrate cycle
VCSRO96_2142	COG1752	Esterase of the alpha-beta hydrolase superfamily
VCSRO96_2143	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VCSRO96_2144	COG1643	Atp-dependent helicase
VCSRO96_2146	COG1489	DNA binding
VCSRO96_2148	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCSRO96_2150	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCSRO96_2151	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VCSRO96_2152	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VCSRO96_2153	COG0842	Transport permease protein
VCSRO96_2154	COG1131	(ABC) transporter
VCSRO96_2155	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO96_2156	COG0288	reversible hydration of carbon dioxide
VCSRO96_2159	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VCSRO96_2160	COG3107	peptidoglycan biosynthetic process
VCSRO96_2161	COG0792	nuclease activity
VCSRO96_2162	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCSRO96_2163	COG2823	Periplasmic or secreted lipoprotein
VCSRO96_2164	COG2969	positive regulation of protein catabolic process
VCSRO96_2165	COG0625	glutathione transferase activity
VCSRO96_2166	COG2857	Cytochrome c1
VCSRO96_2167	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VCSRO96_2168	COG0723	plastoquinol--plastocyanin reductase activity
VCSRO96_2169	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VCSRO96_2170	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VCSRO96_2171	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VCSRO96_2173	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCSRO96_2174	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCSRO96_2175	COG0335	large ribosomal subunit rRNA binding
VCSRO96_2176	COG0336	Belongs to the RNA methyltransferase TrmD family
VCSRO96_2177	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VCSRO96_2178	COG0228	four-way junction DNA binding
VCSRO96_2179	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VCSRO96_2181	COG4137	Cytochrome C assembly protein
VCSRO96_2182	COG4536	flavin adenine dinucleotide binding
VCSRO96_2183	COG1854	S-ribosylhomocysteine lyase activity
VCSRO96_2184	COG2918	glutathione biosynthetic process
VCSRO96_2185	COG0612	Peptidase, M16
VCSRO96_2186	COG1238	metal cluster binding
VCSRO96_2188	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCSRO96_2189	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO96_2189	COG5016	pyruvate
VCSRO96_2190	COG3630	sodium ion export across plasma membrane
VCSRO96_2199	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
VCSRO96_2200	COG0527	aspartate kinase activity
VCSRO96_2201	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VCSRO96_2202	COG2137	regulation of response to DNA damage stimulus
VCSRO96_2203	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VCSRO96_2205	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
VCSRO96_2206	COG4208	sulfate ABC transporter
VCSRO96_2210	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VCSRO96_2211	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCSRO96_2212	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCSRO96_2214	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VCSRO96_2215	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VCSRO96_2216	COG0585	pseudouridine synthase activity
VCSRO96_2217	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VCSRO96_2218	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VCSRO96_2219	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VCSRO96_2220	COG1968	undecaprenyl-diphosphatase activity
VCSRO96_2221	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCSRO96_2222	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VCSRO96_2223	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VCSRO96_2225	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VCSRO96_2226	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VCSRO96_2227	COG1610	YqeY-like protein
VCSRO96_2228	COG0358	DNA primase activity
VCSRO96_2232	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCSRO96_2241	COG0840	transmembrane signaling receptor activity
VCSRO96_2244	COG3547	Transposase (IS116 IS110 IS902 family)
VCSRO96_2245	COG2801	Transposase and inactivated derivatives
VCSRO96_2246	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VCSRO96_2247	COG1349	DNA-binding transcription factor activity
VCSRO96_2252	COG1279	arginine transmembrane transporter activity
VCSRO96_2253	COG0668	transmembrane transport
VCSRO96_2254	COG0191	fructose-bisphosphate aldolase activity
VCSRO96_2255	COG0126	phosphoglycerate kinase activity
VCSRO96_2256	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO96_2257	COG4771	TonB-dependent receptor
VCSRO96_2258	COG0583	DNA-binding transcription factor activity
VCSRO96_2259	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCSRO96_2260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VCSRO96_2262	COG2356	endonuclease I
VCSRO96_2263	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VCSRO96_2264	COG0189	ligase activity
VCSRO96_2265	COG1678	Uncharacterized ACR, COG1678
VCSRO96_2266	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VCSRO96_2267	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCSRO96_2271	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VCSRO96_2272	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VCSRO96_2273	COG0762	integral membrane protein
VCSRO96_2274	COG1872	DUF167
VCSRO96_2276	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VCSRO96_2277	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VCSRO96_2278	COG2066	Belongs to the glutaminase family
VCSRO96_2279	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VCSRO96_2280	COG1194	a g-specific adenine glycosylase
VCSRO96_2281	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VCSRO96_2282	COG0741	lytic transglycosylase activity
VCSRO96_2287	COG0840	transmembrane signaling receptor activity
VCSRO96_2293	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VCSRO96_2294	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VCSRO96_2295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO96_2296	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VCSRO96_2297	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VCSRO96_2298	COG2967	ApaG domain
VCSRO96_2299	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VCSRO96_2301	COG3610	response to peptide
VCSRO96_2302	COG2966	Psort location CytoplasmicMembrane, score
VCSRO96_2303	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VCSRO96_2304	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VCSRO96_2305	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VCSRO96_2306	COG0142	geranyltranstransferase activity
VCSRO96_2307	COG0531	amino acid
VCSRO96_2308	COG0039	L-malate dehydrogenase activity
VCSRO96_2309	COG1438	arginine binding
VCSRO96_2310	COG2358	TRAP transporter, solute receptor (TAXI family
VCSRO96_2312	COG0589	response to stress
VCSRO96_2316	COG2235	arginine
VCSRO96_2317	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCSRO96_2318	COG1151	hydroxylamine reductase activity
VCSRO96_2319	COG0312	modulator of DNA gyrase
VCSRO96_2320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VCSRO96_2322	COG3164	Protein of unknown function
VCSRO96_2324	COG0424	maF-like protein
VCSRO96_2325	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VCSRO96_2326	COG1792	Involved in formation and maintenance of cell shape
VCSRO96_2327	COG1077	Cell shape determining protein MreB Mrl
VCSRO96_2333	COG2165	general secretion pathway protein
VCSRO96_2334	COG2165	general secretion pathway protein
VCSRO96_2336	COG1459	type II secretion system
VCSRO96_2337	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO96_2339	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO96_2339	COG3267	Type II secretory pathway component ExeA
VCSRO96_2344	COG2200	EAL domain
VCSRO96_2344	COG2199	diguanylate cyclase activity
VCSRO96_2345	COG0629	single-stranded DNA binding
VCSRO96_2348	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VCSRO96_2350	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCSRO96_2351	COG0527	aspartate kinase activity
VCSRO96_2352	COG0646	methionine synthase
VCSRO96_2352	COG1410	methionine synthase
VCSRO96_2360	COG0175	sulfate reduction
VCSRO96_2361	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VCSRO96_2362	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCSRO96_2366	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO96_2367	COG0735	belongs to the Fur family
VCSRO96_2370	COG0166	Belongs to the GPI family
VCSRO96_2371	COG0432	Pfam Uncharacterised protein family UPF0047
VCSRO96_2372	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCSRO96_2375	COG0359	binds to the 23S rRNA
VCSRO96_2376	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
VCSRO96_2377	COG2965	DNA replication, synthesis of RNA primer
VCSRO96_2378	COG0360	Binds together with S18 to 16S ribosomal RNA
VCSRO96_2380	COG2906	2 iron, 2 sulfur cluster binding
VCSRO96_2381	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCSRO96_2382	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCSRO96_2383	COG0049	tRNA binding
VCSRO96_2386	COG2923	Belongs to the DsrF TusC family
VCSRO96_2387	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VCSRO96_2388	COG2964	Protein conserved in bacteria
VCSRO96_2389	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO96_2391	COG2900	Belongs to the SlyX family
VCSRO96_2393	COG0330	HflC and HflK could
VCSRO96_2394	COG0330	HflC and HflK could
VCSRO96_2395	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VCSRO96_2396	COG1923	regulation of RNA biosynthetic process
VCSRO96_2397	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VCSRO96_2398	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VCSRO96_2399	COG0860	N-Acetylmuramoyl-L-alanine amidase
VCSRO96_2400	COG0802	atpase or kinase
VCSRO96_2401	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VCSRO96_2410	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VCSRO96_2411	COG1162	GTPase activity
VCSRO96_2412	COG0688	phosphatidylethanolamine metabolic process
VCSRO96_2413	COG0471	metal ion transport
VCSRO96_2415	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VCSRO96_2416	COG4942	peptidase
VCSRO96_2419	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VCSRO96_2420	COG2816	NAD+ diphosphatase activity
VCSRO96_2421	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VCSRO96_2422	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VCSRO96_2423	COG0085	RNA polymerase activity
VCSRO96_2424	COG0222	ribosome binding
VCSRO96_2425	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VCSRO96_2427	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VCSRO96_2428	COG0250	Participates in transcription elongation, termination and antitermination
VCSRO96_2429	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCSRO96_2430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCSRO96_2435	COG1072	(Pantothenic acid kinase))
VCSRO96_2437	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VCSRO96_2439	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VCSRO96_2448	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VCSRO96_2451	COG3118	belongs to the thioredoxin family
VCSRO96_2452	COG0513	Belongs to the DEAD box helicase family
VCSRO96_2453	COG0248	Ppx GppA phosphatase
VCSRO96_2454	COG0784	Response regulator, receiver
VCSRO96_2454	COG2205	protein histidine kinase activity
VCSRO96_2455	COG2814	Major facilitator Superfamily
VCSRO96_2458	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCSRO96_2459	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VCSRO96_2460	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO96_2461	COG0439	Biotin carboxylase
VCSRO96_2462	COG2264	protein methyltransferase activity
VCSRO96_2463	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO96_2464	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VCSRO96_2465	COG1609	Transcriptional regulator
VCSRO96_2466	COG0129	dihydroxy-acid dehydratase activity
VCSRO96_2467	COG3265	gluconokinase activity
VCSRO96_2469	COG0800	Aldolase
VCSRO96_2471	COG3385	transposase activity
VCSRO96_2473	COG0840	transmembrane signaling receptor activity
VCSRO96_2474	COG1982	Orn Lys Arg decarboxylase major
VCSRO96_2475	COG0531	amino acid
VCSRO96_2476	COG3710	Transcriptional regulator
VCSRO96_2477	COG0789	Transcriptional regulator
VCSRO96_2479	COG0151	Belongs to the GarS family
VCSRO96_2481	COG0776	regulation of translation
VCSRO96_2482	COG1253	flavin adenine dinucleotide binding
VCSRO96_2484	COG3068	Protein conserved in bacteria
VCSRO96_2486	COG1573	uracil-dna glycosylase
VCSRO96_2487	COG0668	transmembrane transport
VCSRO96_2490	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VCSRO96_2491	COG3385	transposase activity
VCSRO96_2492	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCSRO96_2493	COG5433	transposase activity
VCSRO96_2494	COG0706	membrane insertase activity
VCSRO96_2497	COG1213	nucleotidyl transferase
VCSRO96_2498	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
VCSRO96_2499	COG3848	Pyruvate phosphate dikinase
VCSRO96_2499	COG0574	Belongs to the PEP-utilizing enzyme family
VCSRO96_2501	COG5433	transposase activity
VCSRO96_2510	COG0110	maltose O-acetyltransferase activity
VCSRO96_2511	COG0110	maltose O-acetyltransferase activity
VCSRO96_2515	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
VCSRO96_2517	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
VCSRO96_2518	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCSRO96_2523	COG0859	PFAM glycosyl transferase family 9
VCSRO96_2525	COG1519	Transferase
VCSRO96_2530	COG3642	lipopolysaccharide core region biosynthetic process
VCSRO96_2531	COG0859	PFAM glycosyl transferase family 9
VCSRO96_2532	COG0463	Glycosyl transferase, family 2
VCSRO96_2533	COG0859	PFAM glycosyl transferase family 9
VCSRO96_2534	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VCSRO96_2535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VCSRO96_2537	COG0267	Belongs to the bacterial ribosomal protein bL33 family
VCSRO96_2538	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VCSRO96_2539	COG2003	Belongs to the UPF0758 family
VCSRO96_2541	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VCSRO96_2542	COG1309	transcriptional regulator
VCSRO96_2543	COG1560	Kdo2-lipid A biosynthetic process
VCSRO96_2544	COG1560	Kdo2-lipid A biosynthetic process
VCSRO96_2545	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VCSRO96_2546	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VCSRO96_2547	COG1561	YicC-like family, N-terminal region
VCSRO96_2557	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VCSRO96_2558	COG3586	endonuclease activity
VCSRO96_2561	COG2862	Uncharacterized protein family, UPF0114
VCSRO96_2562	COG3385	transposase activity
VCSRO96_2563	COG1263	PTS System
VCSRO96_2563	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO96_2564	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCSRO96_2568	COG1120	ATPase activity
VCSRO96_2569	COG4774	siderophore transport
VCSRO96_2570	COG1132	(ABC) transporter
VCSRO96_2573	COG0514	ATP-dependent DNA helicase (RecQ)
VCSRO96_2574	COG2962	Rard protein
VCSRO96_2575	COG0405	Gamma-glutamyltransferase
VCSRO96_2577	COG1280	lysine exporter protein (LysE YggA)
VCSRO96_2578	COG0210	DNA helicase
VCSRO96_2580	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VCSRO96_2581	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO96_2583	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO96_2584	COG0601	transmembrane transport
VCSRO96_2585	COG0747	negative chemotaxis
VCSRO96_2594	COG1309	transcriptional regulator
VCSRO96_2595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO96_2596	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO96_2597	COG2960	long-chain fatty acid transporting porin activity
VCSRO96_2598	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VCSRO96_2599	COG0583	DNA-binding transcription factor activity
VCSRO96_2612	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
VCSRO96_2613	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCSRO96_2614	COG1739	Uncharacterized protein family UPF0029
VCSRO96_2615	COG1024	Enoyl-CoA hydratase
VCSRO96_2615	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCSRO96_2616	COG0183	Belongs to the thiolase family
VCSRO96_2617	COG0583	DNA-binding transcription factor activity
VCSRO96_2618	COG2814	Major facilitator Superfamily
VCSRO96_2620	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VCSRO96_2621	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VCSRO96_2622	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VCSRO96_2623	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VCSRO96_2624	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VCSRO96_2625	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VCSRO96_2627	COG0356	it plays a direct role in the translocation of protons across the membrane
VCSRO96_2628	COG3312	ion transport
VCSRO96_2629	COG1475	DNA binding
VCSRO96_2630	COG1192	Involved in chromosome partitioning
VCSRO96_2631	COG0357	Ribosomal RNA small subunit methyltransferase G
VCSRO96_2632	COG0445	tRNA wobble uridine modification
VCSRO96_2637	COG0217	transcriptional regulatory protein
VCSRO96_2638	COG2084	Dehydrogenase
VCSRO96_2641	COG2909	trisaccharide binding
VCSRO96_2642	COG0058	SHG alpha-glucan phosphorylase activity
VCSRO96_2643	COG1640	4-alpha-glucanotransferase
VCSRO96_2644	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VCSRO96_2646	COG3501	Rhs element vgr protein
VCSRO96_2654	COG0471	metal ion transport
VCSRO96_2655	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCSRO96_2659	COG0840	transmembrane signaling receptor activity
VCSRO96_2663	COG0671	phosphoesterase, PA-phosphatase related
VCSRO96_2664	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VCSRO96_2666	COG1999	signal sequence binding
VCSRO96_2669	COG0786	glutamate:sodium symporter activity
VCSRO96_2675	COG0813	purine-nucleoside phosphorylase activity
VCSRO96_2676	COG3272	Protein of unknown function (DUF1722)
VCSRO96_2678	COG0415	Belongs to the DNA photolyase family
VCSRO96_2679	COG1376	ErfK ybiS ycfS ynhG family protein
VCSRO96_2679	COG1388	LysM domain
VCSRO96_2681	COG0513	Belongs to the DEAD box helicase family
VCSRO96_2682	COG1770	oligopeptidase
VCSRO96_2687	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCSRO96_2688	COG0573	inorganic phosphate transmembrane transporter activity
VCSRO96_2689	COG0581	inorganic phosphate transmembrane transporter activity
VCSRO96_2690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCSRO96_2693	COG3314	Sporulation integral membrane protein YlbJ
VCSRO96_2694	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO96_2696	COG0739	heme binding
VCSRO96_2697	COG3300	MHYT domain
VCSRO96_2697	COG5001	Diguanylate cyclase
VCSRO96_2699	COG0583	DNA-binding transcription factor activity
VCSRO96_2700	COG2814	Major facilitator Superfamily
VCSRO96_2705	COG1301	dicarboxylic acid transport
VCSRO96_2707	COG1342	Belongs to the UPF0251 family
VCSRO96_2713	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VCSRO96_2714	COG0673	inositol 2-dehydrogenase activity
VCSRO96_2716	COG2771	luxR family
VCSRO96_2716	COG2200	EAL domain
VCSRO96_2717	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO96_2719	COG0564	pseudouridine synthase activity
VCSRO96_2732	COG3829	transcription factor binding
VCSRO96_2737	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO96_2737	COG3501	Rhs element vgr protein
VCSRO96_2741	COG1869	D-ribose catabolic process
VCSRO96_2742	COG1129	ABC transporter
VCSRO96_2743	COG1172	Belongs to the binding-protein-dependent transport system permease family
VCSRO96_2744	COG1879	ABC-type sugar transport system periplasmic component
VCSRO96_2745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO96_2746	COG1609	Transcriptional regulator
VCSRO96_2748	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO96_2750	COG0584	glycerophosphoryl diester phosphodiesterase
VCSRO96_2751	COG2271	Major facilitator Superfamily
VCSRO96_2758	COG0579	oxidoreductase
VCSRO96_2760	COG0242	peptide deformylase activity
VCSRO96_2763	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO96_2764	COG1609	Transcriptional regulator
VCSRO96_2766	COG1320	monovalent cation:proton antiporter activity
VCSRO96_2767	COG2212	antiporter activity
VCSRO96_2768	COG1863	multisubunit Na H antiporter MnhE subunit
VCSRO96_2769	COG0651	ATP synthesis coupled electron transport
VCSRO96_2770	COG0651	ATP synthesis coupled electron transport
VCSRO96_2771	COG1006	Multisubunit Na H antiporter MnhC subunit
VCSRO96_2772	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCSRO96_2772	COG2111	Na H antiporter
VCSRO96_2773	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCSRO96_2773	COG2111	Na H antiporter
VCSRO96_2774	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCSRO96_2774	COG2111	Na H antiporter
VCSRO96_2776	COG0589	response to stress
VCSRO96_2777	COG0814	amino acid
VCSRO96_2780	COG3530	Putative quorum-sensing-regulated virulence factor
VCSRO96_2782	COG5001	Diguanylate cyclase
VCSRO96_2782	COG5002	protein histidine kinase activity
VCSRO96_2783	COG1278	Cold shock
VCSRO96_2786	COG2304	oxidoreductase activity
VCSRO96_2790	COG0714	Associated with various cellular activities
VCSRO96_2791	COG0840	transmembrane signaling receptor activity
VCSRO96_2794	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO96_2795	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO96_2797	COG3604	Transcriptional regulator
VCSRO96_2798	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCSRO96_2798	COG1017	nitric oxide dioxygenase activity
VCSRO96_2799	COG1278	Cold shock
VCSRO96_2800	COG3036	rescue of stalled ribosome
VCSRO96_2805	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VCSRO96_2805	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VCSRO96_2806	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCSRO96_2808	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCSRO96_2810	COG0516	GMP reductase activity
VCSRO96_2818	COG5433	transposase activity
VCSRO96_2819	COG1484	DNA-dependent DNA replication
VCSRO96_2820	COG2390	Transcriptional regulator
VCSRO96_2820	COG4584	PFAM Integrase catalytic
VCSRO96_2830	COG0823	Involved in the tonB-independent uptake of proteins
VCSRO96_2831	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCSRO96_2832	COG0534	Mate efflux family protein
VCSRO96_2834	COG1653	transport
VCSRO96_2835	COG3842	ATPase activity
VCSRO96_2836	COG0395	ABC-type sugar transport system, permease component
VCSRO96_2837	COG1175	transmembrane transport
VCSRO96_2840	COG0840	transmembrane signaling receptor activity
VCSRO96_2842	COG0800	Aldolase
VCSRO96_2843	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO96_2845	COG0235	Class ii aldolase
VCSRO96_2847	COG2207	Transcriptional regulator
VCSRO96_2849	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
VCSRO96_2855	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO96_2856	COG1414	Transcriptional regulator
VCSRO96_2857	COG0517	IMP dehydrogenase activity
VCSRO96_2861	COG0513	Belongs to the DEAD box helicase family
VCSRO96_2862	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCSRO96_2863	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VCSRO96_2864	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VCSRO96_2865	COG0784	Response regulator, receiver
VCSRO96_2865	COG3437	response regulator, receiver
VCSRO96_2866	COG4191	Histidine kinase
VCSRO96_2866	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO96_2868	COG1757	Na H antiporter
VCSRO96_2869	COG2814	Major facilitator Superfamily
VCSRO96_2871	COG3706	GGDEF domain
VCSRO96_2872	COG3240	lipase activity
VCSRO96_2874	COG0840	transmembrane signaling receptor activity
VCSRO96_2875	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VCSRO96_2876	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VCSRO96_2877	COG5380	lipid catabolic process
VCSRO96_2882	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO96_2883	COG4605	iron ion homeostasis
VCSRO96_2884	COG4604	ABC transporter, ATP-binding protein
VCSRO96_2885	COG2207	Transcriptional regulator
VCSRO96_2888	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCSRO96_2896	COG0348	domain, Protein
VCSRO96_2901	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
VCSRO96_2906	COG3290	protein histidine kinase activity
VCSRO96_2906	COG0840	transmembrane signaling receptor activity
VCSRO96_2908	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
VCSRO96_2909	COG2197	response regulator
VCSRO96_2910	COG3850	Histidine kinase
VCSRO96_2911	COG2223	nitrite transmembrane transporter activity
VCSRO96_2912	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
VCSRO96_2913	COG1140	nitrate reductase beta subunit
VCSRO96_2914	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
VCSRO96_2915	COG2181	nitrate reductase activity
VCSRO96_2930	COG5433	transposase activity
VCSRO96_2931	COG5433	transposase activity
VCSRO96_2936	COG3550	peptidyl-serine autophosphorylation
VCSRO96_2943	COG0745	RESPONSE REGULATOR receiver
VCSRO96_2945	COG3623	hexulose-6-phosphate isomerase
VCSRO96_2946	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
VCSRO96_2947	COG0561	phosphatase activity
VCSRO96_2956	COG0745	RESPONSE REGULATOR receiver
VCSRO96_2957	COG5002	protein histidine kinase activity
VCSRO96_2960	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO96_2967	COG1686	Belongs to the peptidase S11 family
VCSRO96_2972	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCSRO96_2972	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCSRO96_2973	COG0509	glycine decarboxylation via glycine cleavage system
VCSRO96_2974	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCSRO96_2976	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VCSRO96_2979	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VCSRO96_2980	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
VCSRO96_2987	COG5433	transposase activity
VCSRO96_2989	COG3549	Plasmid maintenance system killer
VCSRO96_2990	COG3093	addiction module antidote protein HigA
VCSRO96_2994	COG3040	lipid binding
VCSRO96_2998	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO96_3018	COG3040	lipid binding
VCSRO96_3019	COG5433	transposase activity
VCSRO96_3032	COG3041	Addiction module toxin RelE StbE family
VCSRO96_3034	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO96_3044	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
VCSRO96_3045	COG2944	sequence-specific DNA binding
VCSRO96_3048	COG0456	acetyltransferase
VCSRO96_3050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO96_3063	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
VCSRO96_3064	COG2944	sequence-specific DNA binding
VCSRO96_3070	COG5433	transposase activity
VCSRO96_3078	COG1418	mRNA catabolic process
VCSRO96_3088	COG3549	Plasmid maintenance system killer
VCSRO96_3089	COG3093	addiction module antidote protein HigA
VCSRO96_3121	COG0494	nUDIX hydrolase
VCSRO96_3129	COG3549	Plasmid maintenance system killer
VCSRO96_3130	COG3093	addiction module antidote protein HigA
VCSRO96_3136	COG1328	CTP reductase activity
VCSRO96_3137	COG0602	queuosine metabolic process
VCSRO96_3139	COG4067	protein conserved in archaea
VCSRO96_3139	COG0189	ligase activity
VCSRO96_3140	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VCSRO96_3140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO96_3140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO96_3141	COG1105	Belongs to the carbohydrate kinase PfkB family
VCSRO96_3142	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO96_3142	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO96_3143	COG1609	Transcriptional regulator
VCSRO96_3144	COG0420	3'-5' exonuclease activity
VCSRO96_3145	COG0419	ATPase involved in DNA repair
VCSRO96_3146	COG0784	Response regulator, receiver
VCSRO96_3146	COG2205	protein histidine kinase activity
VCSRO96_3147	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO96_3149	COG0038	chloride channel
VCSRO96_3150	COG0523	cobalamin synthesis protein
VCSRO96_3152	COG3158	transport of potassium into the cell
VCSRO96_3153	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VCSRO96_3153	COG1013	pyruvate-flavodoxin oxidoreductase activity
VCSRO96_3153	COG0674	pyruvate-flavodoxin oxidoreductase activity
VCSRO96_3153	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
VCSRO96_3154	COG2205	protein histidine kinase activity
VCSRO96_3156	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO96_3157	COG0586	Pfam SNARE associated Golgi protein
VCSRO96_3159	COG2200	EAL domain
VCSRO96_3161	COG3038	cytochrome b561
VCSRO96_3163	COG2116	formate transmembrane transporter activity
VCSRO96_3164	COG0583	DNA-binding transcription factor activity
VCSRO96_3166	COG3593	DNA synthesis involved in DNA repair
VCSRO96_3167	COG0737	Belongs to the 5'-nucleotidase family
VCSRO96_3171	COG2824	Alkylphosphonate utilization operon protein PhnA
VCSRO96_3177	COG2199	diguanylate cyclase activity
VCSRO96_3181	COG3706	GGDEF domain
VCSRO96_3184	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VCSRO96_3185	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VCSRO96_3187	COG0745	RESPONSE REGULATOR receiver
VCSRO96_3190	COG3140	Belongs to the UPF0181 family
VCSRO96_3191	COG0023	Translation Initiation Factor
VCSRO96_3195	COG0045	succinate-CoA ligase (ADP-forming) activity
VCSRO96_3195	COG1042	CoA-binding domain protein
VCSRO96_3195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO96_3196	COG0583	DNA-binding transcription factor activity
VCSRO96_3197	COG4771	TonB-dependent receptor
VCSRO96_3200	COG2050	protein possibly involved in aromatic compounds catabolism
VCSRO96_3204	COG0625	glutathione transferase activity
VCSRO96_3207	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VCSRO96_3208	COG4172	Belongs to the ABC transporter superfamily
VCSRO96_3209	COG4239	(ABC) transporter, permease
VCSRO96_3210	COG4174	ABC transporter (Permease)
VCSRO96_3211	COG4166	transmembrane transport
VCSRO96_3216	COG3104	oligopeptide transport
VCSRO96_3220	COG3842	ATPase activity
VCSRO96_3221	COG1840	ABC-type Fe3 transport system, periplasmic component
VCSRO96_3222	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCSRO96_3223	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VCSRO96_3224	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO96_3225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO96_3227	COG3842	ATPase activity
VCSRO96_3229	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO96_3232	COG1175	transmembrane transport
VCSRO96_3233	COG3833	ABC-type maltose transport systems, permease component
VCSRO96_3237	COG1011	Hydrolase
VCSRO96_3239	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VCSRO96_3240	COG1970	mechanosensitive ion channel activity
VCSRO96_3241	COG2759	Belongs to the formate--tetrahydrofolate ligase family
VCSRO96_3242	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO96_3242	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO96_3243	COG0302	gtp cyclohydrolase
VCSRO96_3245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCSRO96_3247	COG2897	thiosulfate sulfurtransferase activity
VCSRO96_3249	COG2390	Transcriptional regulator
VCSRO96_3251	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCSRO96_3257	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO96_3262	COG0583	DNA-binding transcription factor activity
VCSRO96_3264	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
VCSRO96_3272	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCSRO96_3282	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO96_3282	COG1263	PTS System
VCSRO96_3283	COG1609	Transcriptional regulator
VCSRO96_3284	COG1621	beta-fructofuranosidase activity
VCSRO96_3285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO96_3286	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCSRO96_3287	COG0840	transmembrane signaling receptor activity
VCSRO96_3288	COG2885	chlorophyll binding
VCSRO96_3289	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO96_3290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO96_3292	COG0840	transmembrane signaling receptor activity
VCSRO96_3293	COG3069	C4-dicarboxylate transmembrane transporter activity
VCSRO96_3294	COG1760	l-serine dehydratase
VCSRO96_3295	COG2197	response regulator
VCSRO96_3296	COG3850	Histidine kinase
VCSRO96_3297	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCSRO96_3299	COG0243	molybdopterin cofactor binding
VCSRO96_3303	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO96_3304	COG2197	response regulator
VCSRO96_3305	COG3851	Histidine kinase
VCSRO96_3306	COG2271	Major facilitator Superfamily
VCSRO96_3307	COG1840	ABC-type Fe3 transport system, periplasmic component
VCSRO96_3309	COG3842	ATPase activity
VCSRO96_3310	COG3243	poly(R)-hydroxyalkanoic acid synthase
VCSRO96_3312	COG0183	Belongs to the thiolase family
VCSRO96_3314	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO96_3315	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO96_3319	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCSRO96_3321	COG1979	alcohol dehydrogenase
VCSRO96_3324	COG4191	Histidine kinase
VCSRO96_3327	COG2271	Major facilitator Superfamily
VCSRO96_3328	COG0469	pyruvate kinase activity
VCSRO96_3329	COG0784	Response regulator, receiver
VCSRO96_3329	COG2198	Histidine kinase
VCSRO96_3329	COG2205	protein histidine kinase activity
VCSRO96_3330	COG1879	ABC-type sugar transport system periplasmic component
VCSRO96_3331	COG1803	Methylglyoxal synthase
VCSRO96_3332	COG1335	isochorismatase
VCSRO96_3333	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VCSRO96_3334	COG0210	DNA helicase
VCSRO96_3335	COG1289	transmembrane transporter activity
VCSRO96_3343	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
VCSRO96_3344	COG4149	molybdate abc transporter
VCSRO96_3345	COG0725	ABC transporter, periplasmic molybdate-binding protein
VCSRO96_3346	COG1492	cobalamin metabolic process
VCSRO96_3355	COG0784	Response regulator, receiver
VCSRO96_3355	COG5002	protein histidine kinase activity
VCSRO96_3356	COG1879	ABC-type sugar transport system periplasmic component
VCSRO96_3358	COG2827	Endonuclease containing a URI domain
VCSRO96_3359	COG3132	Protein of unknown function, DUF480
VCSRO96_3361	COG2926	Belongs to the UPF0265 family
VCSRO96_3365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VCSRO96_3366	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCSRO96_3367	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
VCSRO96_3368	COG0247	lactate metabolic process
VCSRO96_3369	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCSRO96_3370	COG3118	belongs to the thioredoxin family
VCSRO96_3375	COG4160	amino acid transport
VCSRO96_3376	COG4215	(ABC) transporter
VCSRO96_3377	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO96_3378	COG1126	abc transporter atp-binding protein
VCSRO96_3380	COG2425	protein containing a von Willebrand factor type A (vWA) domain
VCSRO96_3382	COG0494	nUDIX hydrolase
VCSRO96_3383	COG3385	transposase activity
VCSRO96_3384	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VCSRO96_3386	COG1309	transcriptional regulator
VCSRO96_3387	COG0513	Belongs to the DEAD box helicase family
VCSRO96_3388	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
VCSRO96_3390	COG0814	amino acid
VCSRO96_3391	COG0840	transmembrane signaling receptor activity
VCSRO96_3392	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VCSRO96_3393	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
VCSRO96_3395	COG1984	allophanate hydrolase subunit 2
VCSRO96_3398	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VCSRO96_3399	COG4181	ATPase activity
VCSRO96_3401	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCSRO96_3402	COG5001	Diguanylate cyclase
VCSRO96_3402	COG1716	ATPase activity
VCSRO96_3404	COG0484	heat shock protein binding
VCSRO96_3413	COG5433	transposase activity
VCSRO96_3414	COG5433	transposase activity
VCSRO96_3416	COG5642	Protein of unknown function (DUF2384)
VCSRO96_3425	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
VCSRO96_3427	COG1418	mRNA catabolic process
VCSRO96_3432	COG2161	toxin-antitoxin pair type II binding
VCSRO96_3433	COG4115	mRNA cleavage
VCSRO96_3442	COG0546	phosphoglycolate phosphatase activity
VCSRO96_3445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO96_3447	COG0513	Belongs to the DEAD box helicase family
VCSRO96_3450	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCSRO96_3452	COG3046	protein related to deoxyribodipyrimidine photolyase
VCSRO96_3453	COG3397	chitin binding
VCSRO96_3454	COG3227	Zinc metalloprotease (Elastase)
VCSRO96_3457	COG1166	arginine decarboxylase activity
VCSRO96_3459	COG2239	Acts as a magnesium transporter
VCSRO96_3460	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCSRO96_3461	COG0459	protein refolding
VCSRO96_3463	COG0527	aspartate kinase activity
VCSRO96_3464	COG0662	Cupin 2, conserved barrel domain protein
VCSRO96_3465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VCSRO96_3466	COG0456	acetyltransferase
VCSRO96_3467	COG2154	pterin-4-alpha-carbinolamine dehydratase
VCSRO96_3468	COG3186	Phenylalanine-4-hydroxylase
VCSRO96_3469	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCSRO96_3478	COG1253	flavin adenine dinucleotide binding
VCSRO96_3479	COG1765	OsmC-like protein
VCSRO96_3484	COG0531	amino acid
VCSRO96_3487	COG4989	oxidoreductase activity
VCSRO96_3488	COG0366	Alpha amylase catalytic
VCSRO96_3489	COG2067	long-chain fatty acid transport protein
VCSRO96_3490	COG2267	carboxylic ester hydrolase activity
VCSRO96_3492	COG3227	Zinc metalloprotease (Elastase)
VCSRO96_3493	COG3047	cAMP biosynthetic process
VCSRO96_3496	COG1686	Belongs to the peptidase S11 family
VCSRO96_3497	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VCSRO96_3498	COG1271	oxidase subunit
VCSRO96_3499	COG1294	oxidase, subunit
VCSRO96_3502	COG3048	D-serine ammonia-lyase activity
VCSRO96_3503	COG0583	DNA-binding transcription factor activity
VCSRO96_3506	COG0270	DNA (cytosine-5-)-methyltransferase activity
VCSRO96_3510	COG3385	transposase activity
VCSRO96_3511	COG1063	alcohol dehydrogenase
VCSRO96_3512	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO96_3513	COG2873	o-acetylhomoserine
VCSRO96_3515	COG0346	lactoylglutathione lyase activity
VCSRO96_3519	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
VCSRO96_3520	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO96_3521	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VCSRO96_3522	COG0363	glucosamine-6-phosphate deaminase activity
VCSRO96_3523	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VCSRO96_3528	COG1929	Belongs to the glycerate kinase type-1 family
VCSRO96_3530	COG0748	coenzyme F420 binding
VCSRO96_3531	COG3721	Heme iron utilization protein
VCSRO96_3533	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCSRO96_3534	COG0811	peptide transport
VCSRO96_3535	COG0848	biopolymer transport protein
VCSRO96_3536	COG4558	Periplasmic binding protein
VCSRO96_3537	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO96_3538	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VCSRO96_3545	COG3217	Mosc domain protein beta barrel domain protein
VCSRO96_3545	COG0633	Ferredoxin
VCSRO96_3545	COG3217	Mosc domain protein beta barrel domain protein
VCSRO96_3545	COG0633	Ferredoxin
VCSRO96_3546	COG0418	dihydroorotase activity
VCSRO96_3548	COG3152	Membrane
VCSRO96_3550	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCSRO96_3551	COG2354	Protein conserved in bacteria
VCSRO96_3552	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO96_3553	COG1278	Cold shock
VCSRO96_3558	COG2199	diguanylate cyclase activity
VCSRO96_3559	COG2199	diguanylate cyclase activity
VCSRO96_3560	COG1349	DNA-binding transcription factor activity
VCSRO96_3563	COG3833	ABC-type maltose transport systems, permease component
VCSRO96_3564	COG1175	transmembrane transport
VCSRO96_3566	COG3842	ATPase activity
VCSRO96_3567	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO96_3570	COG0393	Putative heavy-metal-binding
VCSRO96_3572	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO96_3573	COG0784	Response regulator, receiver
VCSRO96_3573	COG0835	chemotaxis
VCSRO96_3574	COG1846	Transcriptional regulator
VCSRO96_3575	COG3706	GGDEF domain
VCSRO96_3582	COG0583	DNA-binding transcription factor activity
VCSRO96_3583	COG5001	Diguanylate cyclase
VCSRO96_3585	COG1741	Belongs to the pirin family
VCSRO96_3586	COG3123	guanosine phosphorylase activity
VCSRO96_3588	COG2211	Major facilitator Superfamily
VCSRO96_3590	COG1067	ATP-dependent peptidase activity
VCSRO96_3592	COG4172	Belongs to the ABC transporter superfamily
VCSRO96_3596	COG0583	DNA-binding transcription factor activity
VCSRO96_3597	COG1620	l-lactate permease
VCSRO96_3600	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
VCSRO96_3602	COG0840	transmembrane signaling receptor activity
VCSRO96_3604	COG0513	Belongs to the DEAD box helicase family
VCSRO96_3606	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
VCSRO96_3608	COG1132	(ABC) transporter
VCSRO96_3610	COG1902	pentaerythritol trinitrate reductase activity
VCSRO96_3612	COG1280	lysine exporter protein (LysE YggA)
VCSRO96_3613	COG2207	Transcriptional regulator
VCSRO96_3617	COG1846	Transcriptional regulator
VCSRO96_3618	COG1764	response to oxidative stress
VCSRO96_3619	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCSRO96_3620	COG0697	spore germination
VCSRO96_3622	COG0700	Nucleoside recognition
VCSRO96_3623	COG3366	ferrous iron transmembrane transporter activity
VCSRO96_3624	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
VCSRO96_3626	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VCSRO96_3627	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
VCSRO96_3628	COG2259	Doxx family
VCSRO96_3633	COG0363	glucosamine-6-phosphate deaminase activity
VCSRO96_3636	COG4580	involved in the transport of maltose and maltodextrins
VCSRO96_3639	COG0840	transmembrane signaling receptor activity
VCSRO96_3641	COG0840	transmembrane signaling receptor activity
VCSRO96_3643	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO96_3644	COG1126	abc transporter atp-binding protein
VCSRO96_3646	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO96_3647	COG4597	amino acid ABC transporter
VCSRO96_3648	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCSRO96_3649	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO96_3649	COG2213	PTS system mannitol-specific
VCSRO96_3650	COG0246	Mannitol dehydrogenase
VCSRO96_3651	COG3722	fumarate hydratase activity
VCSRO96_3652	COG0673	inositol 2-dehydrogenase activity
VCSRO96_3658	COG2910	NAD(P)H-binding
VCSRO96_3660	COG0840	transmembrane signaling receptor activity
VCSRO96_3661	COG4221	oxidoreductase activity
VCSRO96_3663	COG1901	pseudouridine methyltransferase
VCSRO96_3665	COG0531	amino acid
VCSRO96_3666	COG1982	Orn Lys Arg decarboxylase major
VCSRO96_3671	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCSRO96_3676	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VCSRO96_3684	COG0745	RESPONSE REGULATOR receiver
VCSRO96_3689	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCSRO96_3690	COG0840	transmembrane signaling receptor activity
VCSRO96_3692	COG0835	chemotaxis
VCSRO96_3693	COG0835	chemotaxis
VCSRO96_3694	COG0643	Histidine kinase
VCSRO96_3694	COG2198	Histidine kinase
VCSRO96_3695	COG0643	Histidine kinase
VCSRO96_3695	COG2198	Histidine kinase
VCSRO96_3699	COG0601	transmembrane transport
VCSRO96_3700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO96_3702	COG2194	sulfuric ester hydrolase activity
VCSRO96_3703	COG0642	Histidine kinase
VCSRO96_3704	COG0745	RESPONSE REGULATOR receiver
VCSRO96_3709	COG0318	PFAM AMP-dependent synthetase and ligase
VCSRO96_3712	COG1444	tRNA N-acetyltransferase activity
VCSRO96_3713	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine