locus-tag	class	description
VCSRO102_0001	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCSRO102_0008	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VCSRO102_0019	COG4974	Belongs to the 'phage' integrase family
VCSRO102_0022	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
VCSRO102_0023	COG0706	membrane insertase activity
VCSRO102_0024	COG0594	ribonuclease P activity
VCSRO102_0025	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VCSRO102_0026	COG1126	abc transporter atp-binding protein
VCSRO102_0029	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VCSRO102_0030	COG0592	DNA-directed DNA polymerase activity
VCSRO102_0031	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VCSRO102_0032	COG0187	DNA topoisomerase II activity
VCSRO102_0033	COG3385	transposase activity
VCSRO102_0036	COG0071	Belongs to the small heat shock protein (HSP20) family
VCSRO102_0037	COG3977	Valine--pyruvate aminotransferase
VCSRO102_0038	COG0751	glycine-tRNA ligase activity
VCSRO102_0039	COG0752	glycyl-tRNA synthetase alpha subunit
VCSRO102_0040	COG2119	membrane
VCSRO102_0042	COG0425	Belongs to the sulfur carrier protein TusA family
VCSRO102_0044	COG0604	alcohol dehydrogenase
VCSRO102_0046	COG0129	dihydroxy-acid dehydratase activity
VCSRO102_0047	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCSRO102_0050	COG0606	chelatase, subunit chli
VCSRO102_0051	COG0204	Acyl-transferase
VCSRO102_0052	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCSRO102_0053	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VCSRO102_0055	COG3084	Protein conserved in bacteria
VCSRO102_0056	COG4326	sporulation control protein
VCSRO102_0057	COG1272	protein, Hemolysin III
VCSRO102_0059	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCSRO102_0060	COG0569	domain protein
VCSRO102_0061	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VCSRO102_0061	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCSRO102_0062	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VCSRO102_0063	COG0242	peptide deformylase activity
VCSRO102_0064	COG1652	LysM domain
VCSRO102_0065	COG0758	DNA mediated transformation
VCSRO102_0066	COG2922	Belongs to the Smg family
VCSRO102_0067	COG0551	DNA topoisomerase type I activity
VCSRO102_0068	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VCSRO102_0069	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VCSRO102_0070	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VCSRO102_0071	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO102_0072	COG0408	coproporphyrinogen oxidase activity
VCSRO102_0073	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VCSRO102_0075	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VCSRO102_0082	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VCSRO102_0083	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VCSRO102_0085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCSRO102_0086	COG2104	thiamine diphosphate biosynthetic process
VCSRO102_0087	COG2022	thiamine diphosphate biosynthetic process
VCSRO102_0088	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCSRO102_0089	COG0006	proline dipeptidase activity
VCSRO102_0089	COG0006	proline dipeptidase activity
VCSRO102_0093	COG1522	sequence-specific DNA binding
VCSRO102_0094	COG5002	protein histidine kinase activity
VCSRO102_0094	COG5001	Diguanylate cyclase
VCSRO102_0098	COG0589	response to stress
VCSRO102_0099	COG1528	Iron-storage protein
VCSRO102_0101	COG2081	HI0933 family
VCSRO102_0103	COG1322	Protein conserved in bacteria
VCSRO102_0104	COG2226	methyltransferase
VCSRO102_0107	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO102_0108	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO102_0109	COG0805	protein transport
VCSRO102_0110	COG0534	Mate efflux family protein
VCSRO102_0112	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VCSRO102_0114	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VCSRO102_0115	COG3161	chorismate lyase activity
VCSRO102_0116	COG1580	Controls the rotational direction of flagella during chemotaxis
VCSRO102_0117	COG0840	transmembrane signaling receptor activity
VCSRO102_0119	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO102_0120	COG0084	hydrolase, TatD family'
VCSRO102_0123	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO102_0123	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO102_0127	COG3078	GTPase activator activity
VCSRO102_0130	COG3071	HemY protein
VCSRO102_0131	COG2959	enzyme of heme biosynthesis
VCSRO102_0132	COG1587	Uroporphyrinogen-III synthase
VCSRO102_0133	COG0181	hydroxymethylbilane synthase activity
VCSRO102_0135	COG1965	Belongs to the frataxin family
VCSRO102_0136	COG0019	diaminopimelate decarboxylase activity
VCSRO102_0137	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VCSRO102_0139	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VCSRO102_0140	COG1011	Hydrolase
VCSRO102_0141	COG3287	FIST C domain
VCSRO102_0141	COG2200	EAL domain
VCSRO102_0141	COG2199	diguanylate cyclase activity
VCSRO102_0144	COG0561	phosphatase activity
VCSRO102_0145	COG2267	carboxylic ester hydrolase activity
VCSRO102_0146	COG1280	lysine exporter protein (LysE YggA)
VCSRO102_0147	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCSRO102_0148	COG0783	Belongs to the Dps family
VCSRO102_0154	COG0742	ribosomal rna small subunit methyltransferase
VCSRO102_0155	COG0552	protein localization to endoplasmic reticulum
VCSRO102_0156	COG2884	Cell division ATP-binding protein ftsE
VCSRO102_0157	COG2177	Part of the ABC transporter FtsEX involved in
VCSRO102_0158	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCSRO102_0159	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO102_0162	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCSRO102_0165	COG1404	Belongs to the peptidase S8 family
VCSRO102_0166	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
VCSRO102_0175	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VCSRO102_0176	COG3300	MHYT domain
VCSRO102_0176	COG5001	Diguanylate cyclase
VCSRO102_0178	COG3852	Histidine kinase
VCSRO102_0180	COG0174	glutamine synthetase
VCSRO102_0182	COG1217	gtp-binding protein TYPA
VCSRO102_0184	COG1295	ribonuclease BN
VCSRO102_0185	COG1490	D-aminoacyl-tRNA deacylase activity
VCSRO102_0186	COG0456	acetyltransferase
VCSRO102_0188	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
VCSRO102_0189	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VCSRO102_0190	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VCSRO102_0191	COG3031	protein transport across the cell outer membrane
VCSRO102_0193	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO102_0194	COG1459	type II secretion system
VCSRO102_0195	COG2165	general secretion pathway protein
VCSRO102_0196	COG2165	general secretion pathway protein
VCSRO102_0197	COG2165	general secretion pathway protein
VCSRO102_0198	COG4795	General secretion pathway protein
VCSRO102_0199	COG3156	type II secretion system protein K
VCSRO102_0200	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCSRO102_0201	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCSRO102_0203	COG1218	3'(2'),5'-bisphosphate nucleotidase
VCSRO102_0204	COG0494	nUDIX hydrolase
VCSRO102_0206	COG1040	competence protein
VCSRO102_0207	COG0596	Alpha beta hydrolase
VCSRO102_0209	COG2183	response to ionizing radiation
VCSRO102_0210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO102_0211	COG2199	diguanylate cyclase activity
VCSRO102_0214	COG2233	PERMEase
VCSRO102_0215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VCSRO102_0216	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCSRO102_0217	COG1758	RNA polymerase activity
VCSRO102_0218	COG0194	GDP metabolic process
VCSRO102_0219	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VCSRO102_0220	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCSRO102_0224	COG4232	protein-disulfide reductase activity
VCSRO102_0226	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCSRO102_0227	COG1027	Aspartate ammonia-lyase
VCSRO102_0228	COG3706	GGDEF domain
VCSRO102_0229	COG3030	protein affecting phage T7 exclusion by the F plasmid
VCSRO102_0230	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VCSRO102_0232	COG2205	protein histidine kinase activity
VCSRO102_0233	COG0745	RESPONSE REGULATOR receiver
VCSRO102_0235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VCSRO102_0236	COG0205	6-phosphofructokinase activity
VCSRO102_0237	COG1494	fructose-1,6-bisphosphatase
VCSRO102_0238	COG3074	FtsZ-dependent cytokinesis
VCSRO102_0239	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VCSRO102_0240	COG0527	aspartate kinase activity
VCSRO102_0240	COG0460	homoserine dehydrogenase
VCSRO102_0241	COG0626	cystathionine gamma-synthase activity
VCSRO102_0242	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
VCSRO102_0243	COG0281	malic enzyme
VCSRO102_0244	COG0254	rRNA binding
VCSRO102_0245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VCSRO102_0246	COG1609	Transcriptional regulator
VCSRO102_0247	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCSRO102_0248	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VCSRO102_0249	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VCSRO102_0250	COG1575	Belongs to the MenA family. Type 1 subfamily
VCSRO102_0251	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCSRO102_0252	COG0534	Mate efflux family protein
VCSRO102_0253	COG0149	triose-phosphate isomerase activity
VCSRO102_0258	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCSRO102_0259	COG0459	protein refolding
VCSRO102_0261	COG1509	lysine 2,3-aminomutase activity
VCSRO102_0262	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCSRO102_0264	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VCSRO102_0265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VCSRO102_0266	COG1053	succinate dehydrogenase
VCSRO102_0267	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VCSRO102_0268	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO102_0269	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VCSRO102_0270	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VCSRO102_0271	COG1045	serine acetyltransferase
VCSRO102_0273	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VCSRO102_0274	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VCSRO102_0275	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VCSRO102_0276	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCSRO102_0277	COG0137	argininosuccinate synthase activity
VCSRO102_0278	COG0165	Argininosuccinate lyase
VCSRO102_0280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO102_0281	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCSRO102_0281	COG0678	peroxiredoxin activity
VCSRO102_0283	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VCSRO102_0289	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VCSRO102_0290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VCSRO102_0292	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VCSRO102_0293	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VCSRO102_0294	COG0546	phosphoglycolate phosphatase activity
VCSRO102_0295	COG0180	Tryptophanyl-tRNA synthetase
VCSRO102_0298	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCSRO102_0300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VCSRO102_0302	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO102_0305	COG3954	Phosphoribulokinase
VCSRO102_0307	COG0429	hydrolase of the alpha beta-hydrolase fold
VCSRO102_0309	COG0488	(ABC) transporter
VCSRO102_0310	COG2249	NAD(P)H dehydrogenase (quinone) activity
VCSRO102_0313	COG1047	Peptidyl-prolyl cis-trans
VCSRO102_0315	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VCSRO102_0316	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VCSRO102_0318	COG0557	exoribonuclease II activity
VCSRO102_0319	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCSRO102_0320	COG0051	transcription antitermination factor activity, RNA binding
VCSRO102_0321	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VCSRO102_0322	COG0088	Forms part of the polypeptide exit tunnel
VCSRO102_0323	COG0089	rRNA binding
VCSRO102_0324	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VCSRO102_0325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VCSRO102_0326	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VCSRO102_0327	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VCSRO102_0328	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VCSRO102_0329	COG0255	Belongs to the universal ribosomal protein uL29 family
VCSRO102_0330	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VCSRO102_0331	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VCSRO102_0332	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VCSRO102_0333	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VCSRO102_0334	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VCSRO102_0335	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VCSRO102_0336	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
VCSRO102_0337	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VCSRO102_0338	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VCSRO102_0339	COG1841	ribosomal large subunit assembly
VCSRO102_0341	COG0201	protein transport
VCSRO102_0342	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCSRO102_0343	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VCSRO102_0344	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VCSRO102_0345	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VCSRO102_0346	COG0202	RNA polymerase activity
VCSRO102_0347	COG0203	ribosomal protein L17
VCSRO102_0349	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO102_0350	COG3061	Opacity-associated protein A
VCSRO102_0350	COG3266	domain, Protein
VCSRO102_0351	COG0697	spore germination
VCSRO102_0352	COG2153	protein acetylation
VCSRO102_0353	COG0513	Belongs to the DEAD box helicase family
VCSRO102_0355	COG0737	Belongs to the 5'-nucleotidase family
VCSRO102_0356	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VCSRO102_0356	COG1648	precorrin-2 dehydrogenase activity
VCSRO102_0357	COG0175	sulfate reduction
VCSRO102_0358	COG2895	sulfate adenylyltransferase (ATP) activity
VCSRO102_0359	COG0529	Catalyzes the synthesis of activated sulfate
VCSRO102_0363	COG1136	(ABC) transporter
VCSRO102_0366	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VCSRO102_0367	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO102_0368	COG0729	surface antigen
VCSRO102_0370	COG2105	PFAM AIG2 family protein
VCSRO102_0371	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VCSRO102_0373	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCSRO102_0374	COG0163	prenyltransferase activity
VCSRO102_0376	COG1178	ABC-type Fe3 transport system permease component
VCSRO102_0377	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VCSRO102_0378	COG3028	Belongs to the UPF0307 family
VCSRO102_0379	COG0312	modulator of DNA gyrase
VCSRO102_0380	COG2239	Acts as a magnesium transporter
VCSRO102_0381	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO102_0382	COG1660	Displays ATPase and GTPase activities
VCSRO102_0383	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO102_0384	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCSRO102_0386	COG1137	ATPase activity
VCSRO102_0387	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VCSRO102_0390	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VCSRO102_0390	COG0517	IMP dehydrogenase activity
VCSRO102_0392	COG1127	ABC transporter
VCSRO102_0393	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VCSRO102_0394	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCSRO102_0395	COG2854	intermembrane phospholipid transfer
VCSRO102_0397	COG5007	Belongs to the BolA IbaG family
VCSRO102_0398	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VCSRO102_0400	COG0251	oxidation-reduction process
VCSRO102_0402	COG0540	Belongs to the ATCase OTCase family
VCSRO102_0404	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VCSRO102_0405	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VCSRO102_0406	COG0564	pseudouridine synthase activity
VCSRO102_0407	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCSRO102_0408	COG3385	transposase activity
VCSRO102_0409	COG0525	valine-tRNA ligase activity
VCSRO102_0410	COG2927	DNA polymerase III (CHI subunit)
VCSRO102_0411	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCSRO102_0412	COG0795	lipopolysaccharide-transporting ATPase activity
VCSRO102_0413	COG0795	lipopolysaccharide-transporting ATPase activity
VCSRO102_0416	COG3437	response regulator, receiver
VCSRO102_0424	COG0066	3-isopropylmalate dehydratase activity
VCSRO102_0425	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
VCSRO102_0426	COG0473	3-isopropylmalate dehydrogenase activity
VCSRO102_0431	COG0583	DNA-binding transcription factor activity
VCSRO102_0432	COG1022	Amp-dependent synthetase and ligase
VCSRO102_0433	COG0028	Belongs to the TPP enzyme family
VCSRO102_0434	COG0440	acetolactate synthase activity
VCSRO102_0435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO102_0436	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VCSRO102_0437	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VCSRO102_0438	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VCSRO102_0439	COG3079	Belongs to the UPF0149 family
VCSRO102_0440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO102_0441	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO102_0444	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VCSRO102_0445	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VCSRO102_0447	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VCSRO102_0448	COG1595	DNA-templated transcription, initiation
VCSRO102_0451	COG3086	response to oxidative stress
VCSRO102_0452	COG0481	GTPase activity
VCSRO102_0454	COG0571	ribonuclease III activity
VCSRO102_0455	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VCSRO102_0456	COG1381	Involved in DNA repair and RecF pathway recombination
VCSRO102_0457	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VCSRO102_0463	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCSRO102_0464	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCSRO102_0465	COG3956	TIGRFAM MazG family protein
VCSRO102_0466	COG0504	CTP synthase activity
VCSRO102_0467	COG0148	phosphopyruvate hydratase activity
VCSRO102_0469	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO102_0469	COG3267	Type II secretory pathway component ExeA
VCSRO102_0471	COG4991	sh3 domain protein
VCSRO102_0472	COG0306	phosphate transporter
VCSRO102_0473	COG1392	Phosphate transport regulator
VCSRO102_0474	COG3025	triphosphatase activity
VCSRO102_0476	COG0840	transmembrane signaling receptor activity
VCSRO102_0477	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VCSRO102_0478	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
VCSRO102_0478	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
VCSRO102_0479	COG1538	Outer membrane efflux protein
VCSRO102_0480	COG0494	nUDIX hydrolase
VCSRO102_0481	COG3151	Protein conserved in bacteria
VCSRO102_0483	COG3150	esterase
VCSRO102_0484	COG0187	DNA topoisomerase II activity
VCSRO102_0485	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VCSRO102_0487	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VCSRO102_0488	COG0237	dephospho-CoA kinase activity
VCSRO102_0490	COG1459	type II secretion system
VCSRO102_0491	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO102_0495	COG0716	FMN binding
VCSRO102_0496	COG4974	Belongs to the 'phage' integrase family
VCSRO102_0497	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCSRO102_0498	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VCSRO102_0499	COG0737	Belongs to the 5'-nucleotidase family
VCSRO102_0500	COG2186	Transcriptional regulator
VCSRO102_0501	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VCSRO102_0502	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCSRO102_0503	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO102_0505	COG3116	cell division
VCSRO102_0506	COG0768	penicillin binding
VCSRO102_0507	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VCSRO102_0508	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VCSRO102_0510	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VCSRO102_0511	COG0772	Belongs to the SEDS family
VCSRO102_0512	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
VCSRO102_0513	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCSRO102_0514	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VCSRO102_0515	COG0849	cell division
VCSRO102_0516	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VCSRO102_0517	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VCSRO102_0519	COG0653	protein targeting
VCSRO102_0520	COG0494	nUDIX hydrolase
VCSRO102_0521	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
VCSRO102_0522	COG0505	Belongs to the CarA family
VCSRO102_0523	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VCSRO102_0527	COG0730	response to heat
VCSRO102_0528	COG0583	DNA-binding transcription factor activity
VCSRO102_0529	COG2860	membrane
VCSRO102_0530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VCSRO102_0532	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VCSRO102_0534	COG0493	'glutamate synthase
VCSRO102_0535	COG0067	glutamate synthase
VCSRO102_0535	COG0069	glutamate synthase activity
VCSRO102_0535	COG0070	glutamate synthase
VCSRO102_0537	COG0070	glutamate synthase
VCSRO102_0537	COG0069	glutamate synthase activity
VCSRO102_0537	COG0067	glutamate synthase
VCSRO102_0538	COG1242	4 iron, 4 sulfur cluster binding
VCSRO102_0539	COG5001	Diguanylate cyclase
VCSRO102_0539	COG4251	negative regulation of phosphorylation
VCSRO102_0539	COG3706	GGDEF domain
VCSRO102_0539	COG2203	Gaf domain
VCSRO102_0540	COG0784	Response regulator, receiver
VCSRO102_0540	COG2198	Histidine kinase
VCSRO102_0540	COG5002	protein histidine kinase activity
VCSRO102_0541	COG0745	RESPONSE REGULATOR receiver
VCSRO102_0543	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCSRO102_0546	COG0083	homoserine kinase activity
VCSRO102_0547	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VCSRO102_0548	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VCSRO102_0549	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VCSRO102_0550	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VCSRO102_0553	COG1115	amino acid carrier protein
VCSRO102_0554	COG3022	response to hydroperoxide
VCSRO102_0556	COG0084	hydrolase, TatD family'
VCSRO102_0557	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO102_0558	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VCSRO102_0559	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO102_0560	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VCSRO102_0561	COG0813	purine-nucleoside phosphorylase activity
VCSRO102_0563	COG0560	Phosphoserine phosphatase
VCSRO102_0565	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VCSRO102_0566	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCSRO102_0567	COG1022	Amp-dependent synthetase and ligase
VCSRO102_0570	COG3250	beta-galactosidase activity
VCSRO102_0571	COG1609	Transcriptional regulator
VCSRO102_0572	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO102_0577	COG0456	acetyltransferase
VCSRO102_0579	COG2171	N-acyltransferase activity
VCSRO102_0580	COG3141	response to X-ray
VCSRO102_0583	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VCSRO102_0584	COG1074	ATP-dependent DNA helicase activity
VCSRO102_0585	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VCSRO102_0587	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCSRO102_0587	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VCSRO102_0589	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VCSRO102_0590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VCSRO102_0591	COG2166	iron-sulfur cluster assembly
VCSRO102_0592	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCSRO102_0593	COG0693	protein deglycase activity
VCSRO102_0594	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VCSRO102_0595	COG3385	transposase activity
VCSRO102_0596	COG3248	Nucleoside-binding outer membrane protein
VCSRO102_0598	COG1595	DNA-templated transcription, initiation
VCSRO102_0600	COG2211	Major facilitator Superfamily
VCSRO102_0601	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCSRO102_0603	COG2813	Specifically methylates the guanine in position
VCSRO102_0604	COG0271	Belongs to the BolA IbaG family
VCSRO102_0605	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO102_0606	COG1805	sodium ion transport
VCSRO102_0607	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO102_0608	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO102_0609	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCSRO102_0610	COG2871	sodium ion transport
VCSRO102_0611	COG1477	protein flavinylation
VCSRO102_0615	COG3706	GGDEF domain
VCSRO102_0616	COG0733	neurotransmitter:sodium symporter activity
VCSRO102_0617	COG3385	transposase activity
VCSRO102_0619	COG0189	ligase activity
VCSRO102_0620	COG0189	ligase activity
VCSRO102_0620	COG4067	protein conserved in archaea
VCSRO102_0621	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO102_0622	COG2252	PERMEase
VCSRO102_0623	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VCSRO102_0624	COG1073	alpha beta
VCSRO102_0626	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VCSRO102_0627	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VCSRO102_0628	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VCSRO102_0629	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO102_0629	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCSRO102_0632	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VCSRO102_0633	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCSRO102_0634	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VCSRO102_0635	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VCSRO102_0637	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VCSRO102_0638	COG0024	Methionine aminopeptidase
VCSRO102_0639	COG0052	Belongs to the universal ribosomal protein uS2 family
VCSRO102_0640	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VCSRO102_0641	COG0528	UMP kinase activity
VCSRO102_0642	COG0233	cytoplasmic translational termination
VCSRO102_0643	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VCSRO102_0644	COG0575	Belongs to the CDS family
VCSRO102_0645	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VCSRO102_0646	COG0750	zinc metalloprotease
VCSRO102_0648	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VCSRO102_0649	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO102_0650	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCSRO102_0651	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO102_0652	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO102_0653	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
VCSRO102_0654	COG0587	DNA-directed DNA polymerase activity
VCSRO102_0655	COG0825	malonyl-CoA metabolic process
VCSRO102_0656	COG0037	tRNA processing
VCSRO102_0658	COG3479	Phenolic acid decarboxylase
VCSRO102_0659	COG0347	Belongs to the P(II) protein family
VCSRO102_0660	COG3021	interspecies interaction between organisms
VCSRO102_0661	COG1388	LysM domain
VCSRO102_0661	COG0741	lytic transglycosylase activity
VCSRO102_0662	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCSRO102_0663	COG2226	methyltransferase
VCSRO102_0664	COG0328	RNA-DNA hybrid ribonuclease activity
VCSRO102_0667	COG1960	acyl-CoA dehydrogenase activity
VCSRO102_0668	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCSRO102_0669	COG0121	glutamine amidotransferase
VCSRO102_0670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VCSRO102_0671	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VCSRO102_0672	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VCSRO102_0674	COG1187	pseudouridine synthase activity
VCSRO102_0675	COG2840	Smr protein MutS2
VCSRO102_0681	COG2217	Heavy metal translocating P-type atpase
VCSRO102_0681	COG2608	mercury ion transmembrane transporter activity
VCSRO102_0682	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCSRO102_0685	COG1629	transport
VCSRO102_0685	COG4774	siderophore transport
VCSRO102_0686	COG2375	cellular response to nickel ion
VCSRO102_0694	COG0784	Response regulator, receiver
VCSRO102_0694	COG0835	chemotaxis
VCSRO102_0695	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCSRO102_0696	COG1815	bacterial-type flagellum-dependent cell motility
VCSRO102_0699	COG1749	Flagellar hook protein flgE
VCSRO102_0700	COG4787	bacterial-type flagellum-dependent cell motility
VCSRO102_0702	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VCSRO102_0703	COG1706	bacterial-type flagellum-dependent cell motility
VCSRO102_0704	COG1705	Flagellar rod assembly protein muramidase FlgJ
VCSRO102_0704	COG3951	Flagellar rod assembly protein muramidase FlgJ
VCSRO102_0707	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO102_0708	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO102_0725	COG0012	GTP binding
VCSRO102_0726	COG0193	aminoacyl-tRNA hydrolase activity
VCSRO102_0727	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VCSRO102_0728	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VCSRO102_0729	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VCSRO102_0730	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VCSRO102_0731	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VCSRO102_0732	COG2890	protein-(glutamine-N5) methyltransferase activity
VCSRO102_0734	COG2912	Transglutaminase-like superfamily
VCSRO102_0735	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VCSRO102_0736	COG0737	Belongs to the 5'-nucleotidase family
VCSRO102_0737	COG0737	Belongs to the 5'-nucleotidase family
VCSRO102_0738	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VCSRO102_0739	COG2233	PERMEase
VCSRO102_0743	COG1393	Belongs to the ArsC family
VCSRO102_0744	COG4783	chaperone-mediated protein folding
VCSRO102_0748	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VCSRO102_0751	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VCSRO102_0753	COG1876	peptidase activity
VCSRO102_0755	COG1393	Belongs to the ArsC family
VCSRO102_0759	COG2837	iron assimilation
VCSRO102_0760	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO102_0761	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO102_0762	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCSRO102_0763	COG1334	flagellar protein FlaG
VCSRO102_0764	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VCSRO102_0766	COG1516	flagellar protein fliS
VCSRO102_0770	COG1677	Flagellar hook-basal body complex protein FliE
VCSRO102_0772	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VCSRO102_0777	COG1580	Controls the rotational direction of flagella during chemotaxis
VCSRO102_0782	COG1987	bacterial-type flagellum assembly
VCSRO102_0783	COG1684	flagellar biosynthetic protein fliR
VCSRO102_0785	COG2840	Smr protein MutS2
VCSRO102_0786	COG2890	protein-(glutamine-N5) methyltransferase activity
VCSRO102_0787	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VCSRO102_0788	COG2860	membrane
VCSRO102_0789	COG3101	peptidyl-lysine hydroxylation
VCSRO102_0791	COG0431	NADPH-dependent FMN reductase
VCSRO102_0792	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VCSRO102_0792	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VCSRO102_0793	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCSRO102_0794	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO102_0795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCSRO102_0796	COG0735	belongs to the Fur family
VCSRO102_0798	COG0583	DNA-binding transcription factor activity
VCSRO102_0800	COG1346	cytolysis
VCSRO102_0803	COG0596	Alpha beta hydrolase
VCSRO102_0804	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VCSRO102_0805	COG0033	Phosphoglucomutase
VCSRO102_0807	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VCSRO102_0808	COG0372	Belongs to the citrate synthase family
VCSRO102_0809	COG2009	succinate dehydrogenase
VCSRO102_0810	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VCSRO102_0811	COG1053	succinate dehydrogenase
VCSRO102_0813	COG0567	Dehydrogenase, E1 component
VCSRO102_0814	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCSRO102_0815	COG0045	succinate-CoA ligase (ADP-forming) activity
VCSRO102_0817	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VCSRO102_0818	COG1121	(ABC) transporter
VCSRO102_0819	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VCSRO102_0820	COG4977	sequence-specific DNA binding
VCSRO102_0821	COG1918	ferrous iron import across plasma membrane
VCSRO102_0825	COG0018	arginyl-trna synthetase
VCSRO102_0827	COG1025	Belongs to the peptidase M16 family
VCSRO102_0828	COG2062	phosphohistidine phosphatase, SixA
VCSRO102_0834	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VCSRO102_0835	COG0643	Histidine kinase
VCSRO102_0835	COG2198	Histidine kinase
VCSRO102_0835	COG0784	Response regulator, receiver
VCSRO102_0836	COG2201	protein-glutamate methylesterase activity
VCSRO102_0837	COG1192	Involved in chromosome partitioning
VCSRO102_0839	COG0835	chemotaxis
VCSRO102_0841	COG4133	protoheme IX ABC transporter activity
VCSRO102_0842	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCSRO102_0843	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCSRO102_0845	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VCSRO102_0846	COG1138	Cytochrome C-type biogenesis protein
VCSRO102_0847	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VCSRO102_0848	COG3088	subunit of a heme lyase
VCSRO102_0848	COG4235	cytochrome complex assembly
VCSRO102_0850	COG2853	Lipoprotein
VCSRO102_0855	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VCSRO102_0856	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCSRO102_0858	COG0123	including yeast histone deacetylase and acetoin utilization protein
VCSRO102_0861	COG3083	sulfuric ester hydrolase activity
VCSRO102_0862	COG3082	Protein of unknown function (DUF1414)
VCSRO102_0863	COG3081	Nucleoid-associated protein
VCSRO102_0864	COG3385	transposase activity
VCSRO102_0866	COG1757	Na H antiporter
VCSRO102_0867	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCSRO102_0868	COG2095	MarC family integral membrane protein
VCSRO102_0869	COG1454	alcohol dehydrogenase
VCSRO102_0869	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO102_0871	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO102_0872	COG1530	ribonuclease E activity
VCSRO102_0873	COG0564	pseudouridine synthase activity
VCSRO102_0874	COG0424	maF-like protein
VCSRO102_0875	COG1399	metal-binding, possibly nucleic acid-binding protein
VCSRO102_0876	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VCSRO102_0877	COG0416	fatty acid biosynthetic process
VCSRO102_0878	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCSRO102_0880	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO102_0881	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VCSRO102_0882	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCSRO102_0883	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCSRO102_0884	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VCSRO102_0885	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VCSRO102_0887	COG0084	hydrolase, TatD family'
VCSRO102_0888	COG1263	PTS System
VCSRO102_0888	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO102_0890	COG0733	neurotransmitter:sodium symporter activity
VCSRO102_0893	COG4667	esterase of the alpha-beta hydrolase superfamily
VCSRO102_0895	COG1940	carbohydrate kinase activity
VCSRO102_0896	COG0784	Response regulator, receiver
VCSRO102_0896	COG0835	chemotaxis
VCSRO102_0899	COG2226	methyltransferase
VCSRO102_0901	COG0676	glucose-6-phosphate 1-epimerase activity
VCSRO102_0902	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO102_0903	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO102_0905	COG3139	Protein of unknown function (DUF1315)
VCSRO102_0906	COG0252	asparaginase activity
VCSRO102_0907	COG0616	signal peptide processing
VCSRO102_0908	COG1902	pentaerythritol trinitrate reductase activity
VCSRO102_0908	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCSRO102_0909	COG0788	formyltetrahydrofolate deformylase activity
VCSRO102_0911	COG1199	ATP-dependent helicase activity
VCSRO102_0912	COG1214	PFAM Peptidase M22, glycoprotease
VCSRO102_0915	COG0596	Alpha beta hydrolase
VCSRO102_0916	COG0318	PFAM AMP-dependent synthetase and ligase
VCSRO102_0917	COG0318	PFAM AMP-dependent synthetase and ligase
VCSRO102_0918	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VCSRO102_0921	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VCSRO102_0922	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VCSRO102_0923	COG0436	Aminotransferase
VCSRO102_0924	COG1169	isochorismate synthase
VCSRO102_0925	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VCSRO102_0926	COG0596	Alpha beta hydrolase
VCSRO102_0930	COG3135	benzoate transporter
VCSRO102_0931	COG1396	sequence-specific DNA binding
VCSRO102_0932	COG0840	transmembrane signaling receptor activity
VCSRO102_0938	COG3015	lipoprotein NlpE involved in copper resistance
VCSRO102_0939	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VCSRO102_0940	COG2894	cell division
VCSRO102_0941	COG0850	regulation of cytokinetic process
VCSRO102_0942	COG3100	YcgL domain-containing protein
VCSRO102_0943	COG2951	lytic endotransglycosylase activity
VCSRO102_0945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO102_0946	COG3005	denitrification pathway
VCSRO102_0947	COG0243	molybdopterin cofactor binding
VCSRO102_0951	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO102_0953	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VCSRO102_0960	COG4589	Belongs to the CDS family
VCSRO102_0962	COG3300	MHYT domain
VCSRO102_0962	COG5001	Diguanylate cyclase
VCSRO102_0965	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VCSRO102_0966	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCSRO102_0967	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCSRO102_0968	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCSRO102_0970	COG4191	Histidine kinase
VCSRO102_0971	COG0544	peptidyl-prolyl cis-trans isomerase activity
VCSRO102_0973	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VCSRO102_0974	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VCSRO102_0975	COG0776	regulation of translation
VCSRO102_0976	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO102_0977	COG1555	photosystem II stabilization
VCSRO102_0978	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VCSRO102_0979	COG0539	negative regulation of cytoplasmic translation
VCSRO102_0981	COG0776	regulation of translation
VCSRO102_0982	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VCSRO102_0983	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VCSRO102_0987	COG0583	DNA-binding transcription factor activity
VCSRO102_0989	COG0686	Belongs to the AlaDH PNT family
VCSRO102_0991	COG1674	ftsk spoiiie
VCSRO102_0992	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VCSRO102_0993	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCSRO102_0994	COG2186	Transcriptional regulator
VCSRO102_0997	COG0537	adenosine 5'-monophosphoramidase activity
VCSRO102_1002	COG3150	esterase
VCSRO102_1003	COG1252	NADH dehydrogenase
VCSRO102_1007	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VCSRO102_1009	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO102_1010	COG1136	(ABC) transporter
VCSRO102_1011	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO102_1013	COG0658	competence protein
VCSRO102_1013	COG2333	competence protein COMEC
VCSRO102_1014	COG1132	(ABC) transporter
VCSRO102_1015	COG1663	tetraacyldisaccharide 4'-kinase activity
VCSRO102_1016	COG2835	tetraacyldisaccharide 4'-kinase activity
VCSRO102_1017	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VCSRO102_1019	COG2719	SpoVR family
VCSRO102_1020	COG2718	Belongs to the UPF0229 family
VCSRO102_1021	COG2766	serine protein kinase
VCSRO102_1022	COG3385	transposase activity
VCSRO102_1024	COG3385	transposase activity
VCSRO102_1025	COG3013	Belongs to the UPF0304 family
VCSRO102_1027	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VCSRO102_1028	COG0840	transmembrane signaling receptor activity
VCSRO102_1030	COG1882	Formate acetyltransferase
VCSRO102_1036	COG4160	amino acid transport
VCSRO102_1037	COG0708	Exodeoxyribonuclease III
VCSRO102_1038	COG0840	transmembrane signaling receptor activity
VCSRO102_1040	COG3923	Primosomal replication protein n
VCSRO102_1041	COG0730	response to heat
VCSRO102_1042	COG1199	ATP-dependent helicase activity
VCSRO102_1043	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCSRO102_1045	COG3012	SEC-C Motif Domain Protein
VCSRO102_1046	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCSRO102_1047	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCSRO102_1048	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCSRO102_1049	COG0215	cysteine-tRNA ligase activity
VCSRO102_1050	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VCSRO102_1051	COG0632	four-way junction helicase activity
VCSRO102_1054	COG1271	oxidase subunit
VCSRO102_1055	COG1294	oxidase, subunit
VCSRO102_1056	COG4890	Cyd operon protein YbgT
VCSRO102_1057	COG0824	Thioesterase
VCSRO102_1058	COG0811	peptide transport
VCSRO102_1061	COG0823	Involved in the tonB-independent uptake of proteins
VCSRO102_1062	COG2885	chlorophyll binding
VCSRO102_1064	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VCSRO102_1066	COG5002	protein histidine kinase activity
VCSRO102_1066	COG0784	Response regulator, receiver
VCSRO102_1068	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO102_1069	COG3284	Transcriptional regulator
VCSRO102_1070	COG4628	conserved protein (DUF2132)
VCSRO102_1072	COG0415	Belongs to the DNA photolyase family
VCSRO102_1078	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO102_1080	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCSRO102_1080	COG3008	intermembrane lipid transfer
VCSRO102_1081	COG2995	paraquat-inducible protein a
VCSRO102_1082	COG1309	transcriptional regulator
VCSRO102_1083	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO102_1087	COG1960	acyl-CoA dehydrogenase activity
VCSRO102_1088	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCSRO102_1089	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VCSRO102_1091	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VCSRO102_1094	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCSRO102_1095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCSRO102_1096	COG0297	glycogen (starch) synthase activity
VCSRO102_1100	COG3070	regulator of competence-specific genes
VCSRO102_1101	COG1609	Transcriptional regulator
VCSRO102_1103	COG0745	RESPONSE REGULATOR receiver
VCSRO102_1104	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCSRO102_1105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCSRO102_1106	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VCSRO102_1107	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VCSRO102_1109	COG1979	alcohol dehydrogenase
VCSRO102_1110	COG2207	Transcriptional regulator
VCSRO102_1114	COG1032	radical SAM domain protein
VCSRO102_1115	COG5001	Diguanylate cyclase
VCSRO102_1119	COG0583	DNA-binding transcription factor activity
VCSRO102_1120	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VCSRO102_1122	COG2350	Protein conserved in bacteria
VCSRO102_1123	COG1607	acyl-coa hydrolase
VCSRO102_1126	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCSRO102_1127	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCSRO102_1129	COG2116	formate transmembrane transporter activity
VCSRO102_1130	COG4459	periplasmic nitrate reductase
VCSRO102_1131	COG3005	denitrification pathway
VCSRO102_1132	COG0243	molybdopterin cofactor binding
VCSRO102_1135	COG1227	inorganic diphosphatase activity
VCSRO102_1138	COG4172	Belongs to the ABC transporter superfamily
VCSRO102_1141	COG4168	peptide transport system, permease
VCSRO102_1143	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VCSRO102_1144	COG1842	Phage shock protein A
VCSRO102_1147	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO102_1150	COG2818	Glycosylase
VCSRO102_1151	COG0626	cystathionine gamma-synthase activity
VCSRO102_1153	COG0733	neurotransmitter:sodium symporter activity
VCSRO102_1154	COG0564	pseudouridine synthase activity
VCSRO102_1155	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VCSRO102_1156	COG4136	ATPase activity
VCSRO102_1157	COG4135	transport system, permease component
VCSRO102_1158	COG4134	Bacterial extracellular solute-binding protein
VCSRO102_1160	COG3313	Fe-S protein
VCSRO102_1162	COG0842	Transport permease protein
VCSRO102_1163	COG1131	(ABC) transporter
VCSRO102_1164	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO102_1165	COG0814	amino acid
VCSRO102_1168	COG2239	Acts as a magnesium transporter
VCSRO102_1169	COG0784	Response regulator, receiver
VCSRO102_1169	COG2205	protein histidine kinase activity
VCSRO102_1172	COG4934	collagen metabolic process
VCSRO102_1177	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
VCSRO102_1179	COG0840	transmembrane signaling receptor activity
VCSRO102_1181	COG4251	negative regulation of phosphorylation
VCSRO102_1181	COG5001	Diguanylate cyclase
VCSRO102_1181	COG3706	GGDEF domain
VCSRO102_1181	COG2203	Gaf domain
VCSRO102_1182	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VCSRO102_1186	COG1061	Type III restriction enzyme res subunit
VCSRO102_1187	COG1187	pseudouridine synthase activity
VCSRO102_1188	COG2814	Major facilitator Superfamily
VCSRO102_1190	COG0702	epimerase
VCSRO102_1191	COG0534	Mate efflux family protein
VCSRO102_1192	COG4181	ATPase activity
VCSRO102_1193	COG0577	efflux transmembrane transporter activity
VCSRO102_1195	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCSRO102_1197	COG1748	Saccharopine dehydrogenase
VCSRO102_1200	COG1538	Outer membrane efflux protein
VCSRO102_1204	COG0583	DNA-binding transcription factor activity
VCSRO102_1206	COG1451	nucleotide metabolic process
VCSRO102_1209	COG3063	Type IV pilus biogenesis stability protein PilW
VCSRO102_1210	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VCSRO102_1214	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO102_1217	COG3290	protein histidine kinase activity
VCSRO102_1218	COG4565	transcriptional regulatory protein
VCSRO102_1220	COG0835	chemotaxis
VCSRO102_1220	COG0784	Response regulator, receiver
VCSRO102_1228	COG1085	galactose-1-phosphate uridylyltransferase
VCSRO102_1229	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VCSRO102_1230	COG2017	converts alpha-aldose to the beta-anomer
VCSRO102_1232	COG2200	EAL domain
VCSRO102_1232	COG2199	diguanylate cyclase activity
VCSRO102_1235	COG3527	Alpha-acetolactate decarboxylase
VCSRO102_1238	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCSRO102_1243	COG3097	Belongs to the UPF0267 family
VCSRO102_1248	COG1271	oxidase subunit
VCSRO102_1249	COG1294	oxidase, subunit
VCSRO102_1250	COG1136	(ABC) transporter
VCSRO102_1250	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCSRO102_1251	COG0577	efflux transmembrane transporter activity
VCSRO102_1251	COG1136	(ABC) transporter
VCSRO102_1252	COG1136	(ABC) transporter
VCSRO102_1252	COG0577	efflux transmembrane transporter activity
VCSRO102_1256	COG3385	transposase activity
VCSRO102_1259	COG1566	PFAM secretion protein HlyD family protein
VCSRO102_1260	COG2814	Major facilitator Superfamily
VCSRO102_1261	COG0840	transmembrane signaling receptor activity
VCSRO102_1262	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VCSRO102_1264	COG3501	Rhs element vgr protein
VCSRO102_1268	COG1280	lysine exporter protein (LysE YggA)
VCSRO102_1269	COG1115	amino acid carrier protein
VCSRO102_1272	COG2801	Transposase and inactivated derivatives
VCSRO102_1273	COG3385	transposase activity
VCSRO102_1274	COG3385	transposase activity
VCSRO102_1276	COG2723	6-phospho-beta-galactosidase activity
VCSRO102_1277	COG1609	Transcriptional regulator
VCSRO102_1278	COG0251	oxidation-reduction process
VCSRO102_1279	COG2731	YhcH YjgK YiaL family protein
VCSRO102_1280	COG0584	glycerophosphoryl diester phosphodiesterase
VCSRO102_1281	COG1349	DNA-binding transcription factor activity
VCSRO102_1282	COG3842	ATPase activity
VCSRO102_1283	COG0395	ABC-type sugar transport system, permease component
VCSRO102_1284	COG1175	transmembrane transport
VCSRO102_1287	COG0811	peptide transport
VCSRO102_1288	COG0811	peptide transport
VCSRO102_1289	COG0848	biopolymer transport protein
VCSRO102_1290	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCSRO102_1292	COG1793	dna ligase
VCSRO102_1294	COG0534	Mate efflux family protein
VCSRO102_1296	COG3001	Fructosamine kinase
VCSRO102_1298	COG0791	NLP P60 protein
VCSRO102_1299	COG0840	transmembrane signaling receptor activity
VCSRO102_1301	COG3148	PFAM DTW domain containing protein
VCSRO102_1302	COG1940	carbohydrate kinase activity
VCSRO102_1305	COG0746	molybdenum cofactor guanylyltransferase activity
VCSRO102_1306	COG3842	ATPase activity
VCSRO102_1307	COG4662	Binding-protein-dependent transport system inner membrane component
VCSRO102_1309	COG2204	response regulator
VCSRO102_1310	COG3852	Histidine kinase
VCSRO102_1311	COG0488	(ABC) transporter
VCSRO102_1312	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VCSRO102_1318	COG3383	formate dehydrogenase (NAD+) activity
VCSRO102_1318	COG0243	molybdopterin cofactor binding
VCSRO102_1319	COG0437	4 iron, 4 sulfur cluster binding
VCSRO102_1322	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VCSRO102_1323	COG1666	GTP binding
VCSRO102_1324	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO102_1327	COG2996	Protein conserved in bacteria
VCSRO102_1329	COG3008	intermembrane lipid transfer
VCSRO102_1330	COG2995	paraquat-inducible protein a
VCSRO102_1331	COG1132	(ABC) transporter
VCSRO102_1332	COG1956	GAF domain-containing protein
VCSRO102_1333	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VCSRO102_1336	COG0308	aminopeptidase N
VCSRO102_1339	COG0167	dihydroorotate dehydrogenase activity
VCSRO102_1341	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCSRO102_1341	COG0116	Belongs to the methyltransferase superfamily
VCSRO102_1343	COG0488	(ABC) transporter
VCSRO102_1346	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCSRO102_1347	COG1067	ATP-dependent peptidase activity
VCSRO102_1348	COG3120	sequence-specific DNA binding
VCSRO102_1363	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VCSRO102_1363	COG1073	alpha beta
VCSRO102_1363	COG3064	Membrane
VCSRO102_1364	COG2994	toxin metabolic process
VCSRO102_1369	COG0784	Response regulator, receiver
VCSRO102_1369	COG2205	protein histidine kinase activity
VCSRO102_1372	COG3278	Belongs to the heme-copper respiratory oxidase family
VCSRO102_1375	COG2010	Cytochrome c
VCSRO102_1377	COG2217	Heavy metal translocating P-type atpase
VCSRO102_1380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VCSRO102_1381	COG0589	response to stress
VCSRO102_1382	COG0037	tRNA processing
VCSRO102_1386	COG3842	ATPase activity
VCSRO102_1388	COG1177	transmembrane transport
VCSRO102_1390	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCSRO102_1391	COG3385	transposase activity
VCSRO102_1392	COG0513	Belongs to the DEAD box helicase family
VCSRO102_1394	COG0840	transmembrane signaling receptor activity
VCSRO102_1395	COG0840	transmembrane signaling receptor activity
VCSRO102_1395	COG3290	protein histidine kinase activity
VCSRO102_1396	COG0835	chemotaxis
VCSRO102_1397	COG2201	protein-glutamate methylesterase activity
VCSRO102_1399	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCSRO102_1400	COG0643	Histidine kinase
VCSRO102_1400	COG0784	Response regulator, receiver
VCSRO102_1400	COG2198	Histidine kinase
VCSRO102_1401	COG2198	Histidine kinase
VCSRO102_1401	COG0643	Histidine kinase
VCSRO102_1403	COG0745	RESPONSE REGULATOR receiver
VCSRO102_1406	COG0415	Belongs to the DNA photolyase family
VCSRO102_1407	COG0477	Major facilitator Superfamily
VCSRO102_1408	COG0583	DNA-binding transcription factor activity
VCSRO102_1409	COG0402	S-adenosylhomocysteine deaminase activity
VCSRO102_1410	COG0095	Lipoate-protein ligase
VCSRO102_1411	COG0443	Heat shock 70 kDa protein
VCSRO102_1413	COG1643	Atp-dependent helicase
VCSRO102_1419	COG0443	Heat shock 70 kDa protein
VCSRO102_1420	COG0443	Heat shock 70 kDa protein
VCSRO102_1427	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VCSRO102_1428	COG0602	queuosine metabolic process
VCSRO102_1429	COG0561	phosphatase activity
VCSRO102_1431	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO102_1432	COG4597	amino acid ABC transporter
VCSRO102_1433	COG0765	amino acid transport
VCSRO102_1434	COG1126	abc transporter atp-binding protein
VCSRO102_1435	COG0670	Belongs to the BI1 family
VCSRO102_1436	COG2920	part of a sulfur-relay system
VCSRO102_1437	COG1254	Belongs to the acylphosphatase family
VCSRO102_1438	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCSRO102_1439	COG3706	GGDEF domain
VCSRO102_1441	COG3437	response regulator, receiver
VCSRO102_1441	COG3850	Histidine kinase
VCSRO102_1441	COG4999	Histidine kinase
VCSRO102_1441	COG2205	protein histidine kinase activity
VCSRO102_1442	COG3437	response regulator, receiver
VCSRO102_1443	COG0625	glutathione transferase activity
VCSRO102_1445	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VCSRO102_1447	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO102_1453	COG0372	Belongs to the citrate synthase family
VCSRO102_1454	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VCSRO102_1462	COG1129	ABC transporter
VCSRO102_1467	COG0745	RESPONSE REGULATOR receiver
VCSRO102_1468	COG2205	protein histidine kinase activity
VCSRO102_1469	COG3713	MltA-interacting MipA family protein
VCSRO102_1470	COG2990	Protein conserved in bacteria
VCSRO102_1472	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO102_1472	COG4191	Histidine kinase
VCSRO102_1473	COG0471	metal ion transport
VCSRO102_1475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCSRO102_1478	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO102_1480	COG3768	UPF0283 membrane protein
VCSRO102_1481	COG3106	COG3106 Predicted ATPase
VCSRO102_1484	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCSRO102_1485	COG0494	nUDIX hydrolase
VCSRO102_1486	COG0814	amino acid
VCSRO102_1487	COG1760	l-serine dehydratase
VCSRO102_1488	COG0720	synthase
VCSRO102_1489	COG0840	transmembrane signaling receptor activity
VCSRO102_1490	COG0017	Asparaginyl-tRNA synthetase
VCSRO102_1491	COG0351	phosphomethylpyrimidine kinase
VCSRO102_1492	COG3437	response regulator, receiver
VCSRO102_1492	COG2770	Histidine kinase
VCSRO102_1493	COG1448	Aminotransferase
VCSRO102_1496	COG0840	transmembrane signaling receptor activity
VCSRO102_1497	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
VCSRO102_1498	COG2943	transferase activity, transferring hexosyl groups
VCSRO102_1499	COG1609	Transcriptional regulator
VCSRO102_1500	COG3394	polysaccharide catabolic process
VCSRO102_1501	COG1486	melibiose metabolic process
VCSRO102_1502	COG1447	Phosphotransferase system cellobiose-specific component IIA
VCSRO102_1504	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VCSRO102_1505	COG0726	polysaccharide deacetylase
VCSRO102_1506	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VCSRO102_1507	COG1846	Transcriptional regulator
VCSRO102_1512	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCSRO102_1515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCSRO102_1516	COG3108	Peptidase M15
VCSRO102_1522	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VCSRO102_1524	COG2814	Major facilitator Superfamily
VCSRO102_1526	COG1054	Belongs to the UPF0176 family
VCSRO102_1528	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCSRO102_1529	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCSRO102_1530	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCSRO102_1532	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VCSRO102_1533	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VCSRO102_1534	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO102_1535	COG1823	symporter activity
VCSRO102_1536	COG2925	Exonuclease
VCSRO102_1537	COG1380	Effector of murein hydrolase LrgA
VCSRO102_1538	COG1346	cytolysis
VCSRO102_1545	COG0776	regulation of translation
VCSRO102_1546	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO102_1546	COG0072	phenylalanine-tRNA ligase activity
VCSRO102_1547	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VCSRO102_1555	COG0322	excinuclease ABC activity
VCSRO102_1556	COG2197	response regulator
VCSRO102_1557	COG0417	DNA replication proofreading
VCSRO102_1558	COG5001	Diguanylate cyclase
VCSRO102_1560	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCSRO102_1561	COG3099	Belongs to the UPF0263 family
VCSRO102_1564	COG1228	amidohydrolase
VCSRO102_1565	COG0010	Belongs to the arginase family
VCSRO102_1566	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VCSRO102_1567	COG2986	histidine ammonia-lyase
VCSRO102_1571	COG0247	lactate metabolic process
VCSRO102_1571	COG0277	FAD linked oxidase domain protein
VCSRO102_1574	COG2885	chlorophyll binding
VCSRO102_1578	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VCSRO102_1580	COG0281	malic enzyme
VCSRO102_1582	COG2949	membrane
VCSRO102_1583	COG3706	GGDEF domain
VCSRO102_1584	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCSRO102_1586	COG0492	ferredoxin-NADP+ reductase activity
VCSRO102_1587	COG4988	ABC transporter
VCSRO102_1588	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VCSRO102_1589	COG1187	pseudouridine synthase activity
VCSRO102_1590	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO102_1591	COG0613	PHP domain protein
VCSRO102_1592	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCSRO102_1593	COG0512	Glutamine amidotransferase of anthranilate synthase
VCSRO102_1594	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VCSRO102_1595	COG0134	indole-3-glycerol-phosphate synthase activity
VCSRO102_1595	COG0135	phosphoribosylanthranilate isomerase activity
VCSRO102_1596	COG0133	tryptophan synthase activity
VCSRO102_1597	COG0159	tryptophan synthase activity
VCSRO102_1599	COG1435	thymidine kinase activity
VCSRO102_1600	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VCSRO102_1601	COG1801	Protein of unknown function DUF72
VCSRO102_1602	COG4106	trans-aconitate 2-methyltransferase activity
VCSRO102_1603	COG0500	methyltransferase
VCSRO102_1604	COG0189	ligase activity
VCSRO102_1604	COG4067	protein conserved in archaea
VCSRO102_1607	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VCSRO102_1609	COG3852	Histidine kinase
VCSRO102_1612	COG3070	regulator of competence-specific genes
VCSRO102_1614	COG2431	L-lysine efflux transmembrane transporter activity
VCSRO102_1616	COG0076	glutamate decarboxylase activity
VCSRO102_1617	COG1737	Transcriptional regulator
VCSRO102_1618	COG1012	belongs to the aldehyde dehydrogenase family
VCSRO102_1618	COG1454	alcohol dehydrogenase
VCSRO102_1619	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCSRO102_1620	COG3273	potassium ion transport
VCSRO102_1620	COG2985	domain, Protein
VCSRO102_1621	COG0542	response to heat
VCSRO102_1622	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VCSRO102_1623	COG1278	Cold shock
VCSRO102_1625	COG1187	pseudouridine synthase activity
VCSRO102_1626	COG0140	phosphoribosyl-ATP diphosphatase activity
VCSRO102_1626	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VCSRO102_1627	COG0107	imidazoleglycerol-phosphate synthase activity
VCSRO102_1628	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VCSRO102_1629	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VCSRO102_1630	COG0131	Imidazoleglycerol-phosphate dehydratase
VCSRO102_1630	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCSRO102_1631	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VCSRO102_1632	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VCSRO102_1633	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VCSRO102_1634	COG1757	Na H antiporter
VCSRO102_1635	COG2916	Histone family protein nucleoid-structuring protein H-NS
VCSRO102_1636	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO102_1637	COG0482	sulfurtransferase activity
VCSRO102_1638	COG2915	High frequency lysogenization protein hflD homolog
VCSRO102_1639	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VCSRO102_1641	COG2268	Band 7 protein
VCSRO102_1643	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VCSRO102_1646	COG0300	oxidoreductase activity
VCSRO102_1648	COG0501	Belongs to the peptidase M48B family
VCSRO102_1650	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VCSRO102_1651	COG2226	methyltransferase
VCSRO102_1652	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO102_1653	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCSRO102_1654	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VCSRO102_1655	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VCSRO102_1656	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VCSRO102_1657	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VCSRO102_1658	COG0653	protein targeting
VCSRO102_1659	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO102_1660	COG2203	Gaf domain
VCSRO102_1660	COG2199	diguanylate cyclase activity
VCSRO102_1662	COG4120	Belongs to the binding-protein-dependent transport system permease family
VCSRO102_1664	COG4628	conserved protein (DUF2132)
VCSRO102_1665	COG3092	negative regulation of chromosome organization
VCSRO102_1666	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCSRO102_1667	COG0280	phosphate acetyltransferase
VCSRO102_1667	COG0857	belongs to the CobB CobQ family
VCSRO102_1668	COG0435	Glutathione S-transferase
VCSRO102_1669	COG4608	Belongs to the ABC transporter superfamily
VCSRO102_1670	COG0444	Belongs to the ABC transporter superfamily
VCSRO102_1671	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO102_1672	COG0601	transmembrane transport
VCSRO102_1677	COG2204	response regulator
VCSRO102_1678	COG3300	MHYT domain
VCSRO102_1678	COG5001	Diguanylate cyclase
VCSRO102_1679	COG4191	Histidine kinase
VCSRO102_1680	COG5002	protein histidine kinase activity
VCSRO102_1682	COG2201	protein-glutamate methylesterase activity
VCSRO102_1685	COG0009	L-threonylcarbamoyladenylate synthase
VCSRO102_1688	COG1881	PFAM PEBP family protein
VCSRO102_1693	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO102_1694	COG0640	Transcriptional regulator
VCSRO102_1695	COG0454	-acetyltransferase
VCSRO102_1697	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO102_1698	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO102_1700	COG5002	protein histidine kinase activity
VCSRO102_1701	COG3706	GGDEF domain
VCSRO102_1705	COG1946	Acyl-CoA thioesterase
VCSRO102_1706	COG1522	sequence-specific DNA binding
VCSRO102_1708	COG0616	signal peptide processing
VCSRO102_1709	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO102_1710	COG2983	Belongs to the UPF0260 family
VCSRO102_1712	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VCSRO102_1713	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VCSRO102_1714	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
VCSRO102_1715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VCSRO102_1716	COG2832	Protein of unknown function (DUF454)
VCSRO102_1718	COG0745	RESPONSE REGULATOR receiver
VCSRO102_1719	COG0583	DNA-binding transcription factor activity
VCSRO102_1720	COG0778	Nitroreductase
VCSRO102_1721	COG1024	Enoyl-CoA hydratase
VCSRO102_1721	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCSRO102_1722	COG0183	Belongs to the thiolase family
VCSRO102_1725	COG2067	long-chain fatty acid transport protein
VCSRO102_1727	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VCSRO102_1728	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VCSRO102_1729	COG2982	Protein involved in outer membrane biogenesis
VCSRO102_1730	COG0572	uridine kinase
VCSRO102_1731	COG0489	protein tyrosine kinase activity
VCSRO102_1732	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO102_1732	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCSRO102_1734	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO102_1736	COG0517	IMP dehydrogenase activity
VCSRO102_1736	COG0617	tRNA 3'-terminal CCA addition
VCSRO102_1736	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
VCSRO102_1737	COG2199	diguanylate cyclase activity
VCSRO102_1738	COG0314	molybdopterin synthase activity
VCSRO102_1739	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VCSRO102_1740	COG0315	cyclic pyranopterin monophosphate synthase activity
VCSRO102_1741	COG0521	Mo-molybdopterin cofactor biosynthetic process
VCSRO102_1742	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VCSRO102_1743	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VCSRO102_1744	COG2198	Histidine kinase
VCSRO102_1745	COG2204	response regulator
VCSRO102_1746	COG0556	nucleotide-excision repair
VCSRO102_1748	COG4657	Part of a membrane complex involved in electron transport
VCSRO102_1749	COG2878	Part of a membrane complex involved in electron transport
VCSRO102_1750	COG4656	Part of a membrane complex involved in electron transport
VCSRO102_1753	COG4660	Part of a membrane complex involved in electron transport
VCSRO102_1754	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VCSRO102_1755	COG0346	lactoylglutathione lyase activity
VCSRO102_1758	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VCSRO102_1759	COG2056	Na+-H+ antiporter family
VCSRO102_1760	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VCSRO102_1761	COG1286	toxin biosynthetic process
VCSRO102_1762	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VCSRO102_1763	COG0285	dihydrofolate synthase activity
VCSRO102_1764	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VCSRO102_1765	COG0101	tRNA pseudouridine synthase activity
VCSRO102_1768	COG1263	PTS System
VCSRO102_1768	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO102_1768	COG2190	(PTS) system
VCSRO102_1769	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VCSRO102_1770	COG1846	Transcriptional regulator
VCSRO102_1770	COG1940	carbohydrate kinase activity
VCSRO102_1771	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCSRO102_1771	COG4651	solute:proton antiporter activity
VCSRO102_1772	COG0367	asparagine synthase
VCSRO102_1775	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VCSRO102_1776	COG0563	adenylate kinase activity
VCSRO102_1777	COG0326	Molecular chaperone. Has ATPase activity
VCSRO102_1778	COG3710	Transcriptional regulator
VCSRO102_1781	COG0622	Phosphoesterase
VCSRO102_1782	COG1090	epimerase
VCSRO102_1783	COG0300	oxidoreductase activity
VCSRO102_1784	COG3118	belongs to the thioredoxin family
VCSRO102_1785	COG0330	HflC and HflK could
VCSRO102_1786	COG1585	Membrane protein implicated in regulation of membrane protease activity
VCSRO102_1787	COG0789	Transcriptional regulator
VCSRO102_1788	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCSRO102_1790	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VCSRO102_1791	COG3115	cell septum assembly
VCSRO102_1792	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VCSRO102_1793	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VCSRO102_1794	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO102_1796	COG2190	(PTS) system
VCSRO102_1797	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCSRO102_1798	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCSRO102_1799	COG1702	phosphate starvation-inducible protein PhoH
VCSRO102_1800	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VCSRO102_1801	COG4535	Mg2 and Co2 transporter CorC
VCSRO102_1802	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VCSRO102_1803	COG2888	peptidyl-tyrosine sulfation
VCSRO102_1804	COG0495	leucyl-tRNA aminoacylation
VCSRO102_1805	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VCSRO102_1806	COG1466	dna polymerase III delta subunit
VCSRO102_1807	COG0799	negative regulation of ribosome biogenesis
VCSRO102_1808	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VCSRO102_1809	COG0768	penicillin binding
VCSRO102_1810	COG0772	Belongs to the SEDS family
VCSRO102_1811	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCSRO102_1812	COG1686	Belongs to the peptidase S11 family
VCSRO102_1813	COG2921	Belongs to the UPF0250 family
VCSRO102_1814	COG0321	lipoyl(octanoyl) transferase activity
VCSRO102_1815	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VCSRO102_1817	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCSRO102_1822	COG1596	polysaccharide export
VCSRO102_1824	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCSRO102_1835	COG1045	serine acetyltransferase
VCSRO102_1837	COG0438	transferase activity, transferring glycosyl groups
VCSRO102_1841	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VCSRO102_1842	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VCSRO102_1843	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VCSRO102_1844	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO102_1850	COG0366	Alpha amylase catalytic
VCSRO102_1851	COG1263	PTS System
VCSRO102_1851	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO102_1852	COG1609	Transcriptional regulator
VCSRO102_1853	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCSRO102_1854	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VCSRO102_1855	COG2011	ABC-type metal ion transport system permease component
VCSRO102_1856	COG1464	Belongs to the NlpA lipoprotein family
VCSRO102_1857	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VCSRO102_1859	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCSRO102_1859	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCSRO102_1862	COG1611	Belongs to the LOG family
VCSRO102_1863	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCSRO102_1864	COG2363	Small membrane protein
VCSRO102_1865	COG0583	DNA-binding transcription factor activity
VCSRO102_1866	COG0301	tRNA thio-modification
VCSRO102_1866	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCSRO102_1868	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VCSRO102_1869	COG1722	exodeoxyribonuclease VII activity
VCSRO102_1870	COG0142	geranyltranstransferase activity
VCSRO102_1871	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VCSRO102_1872	COG0564	pseudouridine synthase activity
VCSRO102_1873	COG3098	single-species biofilm formation
VCSRO102_1876	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO102_1878	COG1671	Belongs to the UPF0178 family
VCSRO102_1879	COG3385	transposase activity
VCSRO102_1880	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCSRO102_1881	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCSRO102_1882	COG0254	rRNA binding
VCSRO102_1883	COG1720	tRNA m6t6A37 methyltransferase activity
VCSRO102_1884	COG0442	prolyl-tRNA aminoacylation
VCSRO102_1888	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VCSRO102_1888	COG0047	phosphoribosylformylglycinamidine synthase activity
VCSRO102_1889	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VCSRO102_1892	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCSRO102_1898	COG0484	heat shock protein binding
VCSRO102_1899	COG0443	Heat shock 70 kDa protein
VCSRO102_1900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VCSRO102_1901	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VCSRO102_1902	COG0497	DNA recombination
VCSRO102_1903	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO102_1904	COG2914	Belongs to the UPF0125 (RnfH) family
VCSRO102_1905	COG2867	negative regulation of translational initiation
VCSRO102_1906	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VCSRO102_1908	COG0582	viral genome integration into host DNA
VCSRO102_1912	COG1203	CRISPR-associated helicase, Cas3
VCSRO102_1913	COG1518	maintenance of DNA repeat elements
VCSRO102_1916	COG3501	Rhs element vgr protein
VCSRO102_1928	COG2003	Belongs to the UPF0758 family
VCSRO102_1940	COG0514	ATP-dependent DNA helicase (RecQ)
VCSRO102_1944	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VCSRO102_1945	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VCSRO102_1946	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCSRO102_1950	COG3051	citrate lyase alpha subunit
VCSRO102_1951	COG2301	Belongs to the HpcH HpaI aldolase family
VCSRO102_1953	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
VCSRO102_1955	COG3630	sodium ion export across plasma membrane
VCSRO102_1956	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO102_1956	COG5016	pyruvate
VCSRO102_1957	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCSRO102_1959	COG4565	transcriptional regulatory protein
VCSRO102_1964	COG1115	amino acid carrier protein
VCSRO102_1965	COG2977	Belongs to the P-Pant transferase superfamily
VCSRO102_1966	COG1120	ATPase activity
VCSRO102_1967	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO102_1968	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO102_1969	COG4592	Periplasmic binding protein
VCSRO102_1971	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO102_1972	COG1169	isochorismate synthase
VCSRO102_1973	COG1021	2,3-dihydroxybenzoate-AMP ligase
VCSRO102_1974	COG1535	isochorismatase
VCSRO102_1974	COG3433	isochorismatase activity
VCSRO102_1975	COG1584	GPR1 FUN34 yaaH family protein
VCSRO102_1977	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VCSRO102_1977	COG0519	Catalyzes the synthesis of GMP from XMP
VCSRO102_1978	COG0517	IMP dehydrogenase activity
VCSRO102_1978	COG0516	GMP reductase activity
VCSRO102_1979	COG1570	exodeoxyribonuclease VII activity
VCSRO102_1982	COG1160	GTP binding
VCSRO102_1983	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO102_1984	COG2976	Protein conserved in bacteria
VCSRO102_1985	COG0124	histidyl-tRNA synthetase
VCSRO102_1986	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VCSRO102_1989	COG0105	UTP biosynthetic process
VCSRO102_1990	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCSRO102_1991	COG2975	iron-sulfur cluster assembly
VCSRO102_1992	COG0633	Ferredoxin
VCSRO102_1996	COG0822	iron-sulfur transferase activity
VCSRO102_1997	COG1104	cysteine desulfurase activity
VCSRO102_1998	COG1959	2 iron, 2 sulfur cluster binding
VCSRO102_2000	COG0483	inositol monophosphate 1-phosphatase activity
VCSRO102_2001	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO102_2002	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO102_2003	COG1862	Preprotein translocase
VCSRO102_2005	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
VCSRO102_2006	COG0517	IMP dehydrogenase activity
VCSRO102_2008	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VCSRO102_2009	COG0583	DNA-binding transcription factor activity
VCSRO102_2010	COG0450	alkyl hydroperoxide reductase
VCSRO102_2011	COG3142	Participates in the control of copper homeostasis
VCSRO102_2014	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCSRO102_2015	COG0581	inorganic phosphate transmembrane transporter activity
VCSRO102_2017	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VCSRO102_2018	COG0248	Ppx GppA phosphatase
VCSRO102_2020	COG5002	protein histidine kinase activity
VCSRO102_2021	COG0745	RESPONSE REGULATOR receiver
VCSRO102_2023	COG0826	peptidase U32
VCSRO102_2024	COG0826	peptidase U32
VCSRO102_2025	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCSRO102_2035	COG0542	response to heat
VCSRO102_2036	COG1496	oxidoreductase activity
VCSRO102_2037	COG0564	pseudouridine synthase activity
VCSRO102_2038	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCSRO102_2039	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCSRO102_2040	COG1605	Chorismate mutase
VCSRO102_2040	COG0077	Prephenate dehydratase
VCSRO102_2041	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCSRO102_2042	COG5001	Diguanylate cyclase
VCSRO102_2044	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VCSRO102_2046	COG0488	(ABC) transporter
VCSRO102_2048	COG0287	Prephenate dehydrogenase
VCSRO102_2048	COG1605	Chorismate mutase
VCSRO102_2049	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO102_2050	COG3275	phosphorelay sensor kinase activity
VCSRO102_2051	COG3279	Response regulator of the LytR AlgR family
VCSRO102_2053	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VCSRO102_2054	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VCSRO102_2055	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCSRO102_2058	COG1966	Carbon starvation protein
VCSRO102_2059	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VCSRO102_2060	COG1047	Peptidyl-prolyl cis-trans
VCSRO102_2061	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VCSRO102_2063	COG0196	riboflavin kinase activity
VCSRO102_2064	COG0728	peptidoglycan biosynthetic process
VCSRO102_2065	COG0268	Binds directly to 16S ribosomal RNA
VCSRO102_2066	COG0640	Transcriptional regulator
VCSRO102_2067	COG0583	DNA-binding transcription factor activity
VCSRO102_2068	COG1283	sodium-dependent phosphate transmembrane transporter activity
VCSRO102_2070	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VCSRO102_2071	COG0730	response to heat
VCSRO102_2072	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
VCSRO102_2073	COG0494	nUDIX hydrolase
VCSRO102_2075	COG0667	Aldo Keto reductase
VCSRO102_2077	COG2204	response regulator
VCSRO102_2078	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VCSRO102_2079	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VCSRO102_2082	COG0513	Belongs to the DEAD box helicase family
VCSRO102_2083	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
VCSRO102_2087	COG3153	acetyltransferase
VCSRO102_2088	COG3154	lipid carrier protein
VCSRO102_2090	COG0826	peptidase U32
VCSRO102_2091	COG0826	peptidase U32
VCSRO102_2095	COG1185	polyribonucleotide nucleotidyltransferase activity
VCSRO102_2096	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VCSRO102_2098	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VCSRO102_2099	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VCSRO102_2100	COG0195	Participates in both transcription termination and antitermination
VCSRO102_2101	COG0779	Required for maturation of 30S ribosomal subunits
VCSRO102_2104	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCSRO102_2107	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VCSRO102_2108	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VCSRO102_2109	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VCSRO102_2110	COG1534	Rna-binding protein
VCSRO102_2111	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO102_2112	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCSRO102_2113	COG2027	D-alanyl-D-alanine carboxypeptidase
VCSRO102_2114	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCSRO102_2115	COG0739	heme binding
VCSRO102_2118	COG0316	Belongs to the HesB IscA family
VCSRO102_2119	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VCSRO102_2121	COG0628	permease
VCSRO102_2122	COG2813	Specifically methylates the guanine in position
VCSRO102_2123	COG0784	Response regulator, receiver
VCSRO102_2123	COG2205	protein histidine kinase activity
VCSRO102_2124	COG0747	negative chemotaxis
VCSRO102_2125	COG0601	transmembrane transport
VCSRO102_2126	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO102_2127	COG0444	Belongs to the ABC transporter superfamily
VCSRO102_2128	COG4608	Belongs to the ABC transporter superfamily
VCSRO102_2130	COG2971	BadF BadG BcrA BcrD
VCSRO102_2133	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCSRO102_2134	COG3842	ATPase activity
VCSRO102_2136	COG1840	ABC-type Fe3 transport system, periplasmic component
VCSRO102_2137	COG0004	ammonium transporteR
VCSRO102_2138	COG0347	Belongs to the P(II) protein family
VCSRO102_2139	COG3112	Uncharacterised protein family (UPF0231)
VCSRO102_2140	COG1049	propionate catabolic process, 2-methylcitrate cycle
VCSRO102_2141	COG1752	Esterase of the alpha-beta hydrolase superfamily
VCSRO102_2142	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VCSRO102_2143	COG1643	Atp-dependent helicase
VCSRO102_2145	COG1489	DNA binding
VCSRO102_2147	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCSRO102_2149	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCSRO102_2150	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VCSRO102_2151	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VCSRO102_2152	COG0842	Transport permease protein
VCSRO102_2153	COG1131	(ABC) transporter
VCSRO102_2154	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO102_2155	COG0288	reversible hydration of carbon dioxide
VCSRO102_2159	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VCSRO102_2160	COG3107	peptidoglycan biosynthetic process
VCSRO102_2161	COG0792	nuclease activity
VCSRO102_2162	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCSRO102_2163	COG2823	Periplasmic or secreted lipoprotein
VCSRO102_2164	COG2969	positive regulation of protein catabolic process
VCSRO102_2165	COG0625	glutathione transferase activity
VCSRO102_2166	COG2857	Cytochrome c1
VCSRO102_2167	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VCSRO102_2168	COG0723	plastoquinol--plastocyanin reductase activity
VCSRO102_2169	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VCSRO102_2170	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VCSRO102_2171	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VCSRO102_2173	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCSRO102_2174	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCSRO102_2175	COG0335	large ribosomal subunit rRNA binding
VCSRO102_2176	COG0336	Belongs to the RNA methyltransferase TrmD family
VCSRO102_2177	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VCSRO102_2178	COG0228	four-way junction DNA binding
VCSRO102_2179	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VCSRO102_2181	COG4137	Cytochrome C assembly protein
VCSRO102_2182	COG4536	flavin adenine dinucleotide binding
VCSRO102_2183	COG1854	S-ribosylhomocysteine lyase activity
VCSRO102_2184	COG2918	glutathione biosynthetic process
VCSRO102_2185	COG0612	Peptidase, M16
VCSRO102_2186	COG1238	metal cluster binding
VCSRO102_2188	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCSRO102_2189	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO102_2189	COG5016	pyruvate
VCSRO102_2190	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO102_2190	COG5016	pyruvate
VCSRO102_2191	COG3630	sodium ion export across plasma membrane
VCSRO102_2200	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
VCSRO102_2201	COG0527	aspartate kinase activity
VCSRO102_2202	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VCSRO102_2203	COG2137	regulation of response to DNA damage stimulus
VCSRO102_2204	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VCSRO102_2206	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
VCSRO102_2207	COG4208	sulfate ABC transporter
VCSRO102_2211	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VCSRO102_2212	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCSRO102_2213	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCSRO102_2215	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VCSRO102_2216	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VCSRO102_2217	COG0585	pseudouridine synthase activity
VCSRO102_2218	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VCSRO102_2219	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VCSRO102_2220	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VCSRO102_2221	COG1968	undecaprenyl-diphosphatase activity
VCSRO102_2222	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCSRO102_2223	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VCSRO102_2224	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VCSRO102_2226	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VCSRO102_2227	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VCSRO102_2228	COG1610	YqeY-like protein
VCSRO102_2233	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCSRO102_2234	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VCSRO102_2235	COG1349	DNA-binding transcription factor activity
VCSRO102_2237	COG3385	transposase activity
VCSRO102_2241	COG1279	arginine transmembrane transporter activity
VCSRO102_2242	COG0668	transmembrane transport
VCSRO102_2243	COG0191	fructose-bisphosphate aldolase activity
VCSRO102_2244	COG0126	phosphoglycerate kinase activity
VCSRO102_2245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCSRO102_2246	COG4771	TonB-dependent receptor
VCSRO102_2247	COG0583	DNA-binding transcription factor activity
VCSRO102_2248	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCSRO102_2249	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VCSRO102_2250	COG3091	SprT-like family
VCSRO102_2251	COG2356	endonuclease I
VCSRO102_2252	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VCSRO102_2253	COG0189	ligase activity
VCSRO102_2254	COG1678	Uncharacterized ACR, COG1678
VCSRO102_2255	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VCSRO102_2256	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCSRO102_2260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VCSRO102_2261	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VCSRO102_2262	COG0762	integral membrane protein
VCSRO102_2265	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VCSRO102_2266	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VCSRO102_2267	COG2066	Belongs to the glutaminase family
VCSRO102_2268	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VCSRO102_2269	COG1194	a g-specific adenine glycosylase
VCSRO102_2270	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VCSRO102_2271	COG0741	lytic transglycosylase activity
VCSRO102_2282	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VCSRO102_2283	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VCSRO102_2284	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO102_2285	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VCSRO102_2286	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VCSRO102_2287	COG2967	ApaG domain
VCSRO102_2288	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VCSRO102_2290	COG3610	response to peptide
VCSRO102_2291	COG2966	Psort location CytoplasmicMembrane, score
VCSRO102_2292	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VCSRO102_2293	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VCSRO102_2294	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VCSRO102_2295	COG0142	geranyltranstransferase activity
VCSRO102_2296	COG0531	amino acid
VCSRO102_2297	COG0039	L-malate dehydrogenase activity
VCSRO102_2298	COG1438	arginine binding
VCSRO102_2299	COG2358	TRAP transporter, solute receptor (TAXI family
VCSRO102_2301	COG0589	response to stress
VCSRO102_2305	COG2235	arginine
VCSRO102_2306	COG0312	modulator of DNA gyrase
VCSRO102_2307	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VCSRO102_2308	COG3164	Protein of unknown function
VCSRO102_2310	COG0424	maF-like protein
VCSRO102_2311	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VCSRO102_2312	COG1792	Involved in formation and maintenance of cell shape
VCSRO102_2313	COG1077	Cell shape determining protein MreB Mrl
VCSRO102_2319	COG2165	general secretion pathway protein
VCSRO102_2320	COG2165	general secretion pathway protein
VCSRO102_2322	COG1459	type II secretion system
VCSRO102_2323	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCSRO102_2325	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO102_2325	COG3267	Type II secretory pathway component ExeA
VCSRO102_2330	COG2199	diguanylate cyclase activity
VCSRO102_2330	COG2200	EAL domain
VCSRO102_2331	COG0629	single-stranded DNA binding
VCSRO102_2334	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VCSRO102_2336	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCSRO102_2337	COG0527	aspartate kinase activity
VCSRO102_2338	COG0646	methionine synthase
VCSRO102_2338	COG1410	methionine synthase
VCSRO102_2346	COG0175	sulfate reduction
VCSRO102_2348	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCSRO102_2352	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO102_2353	COG0735	belongs to the Fur family
VCSRO102_2357	COG0166	Belongs to the GPI family
VCSRO102_2358	COG0432	Pfam Uncharacterised protein family UPF0047
VCSRO102_2359	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCSRO102_2362	COG0359	binds to the 23S rRNA
VCSRO102_2363	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
VCSRO102_2364	COG2965	DNA replication, synthesis of RNA primer
VCSRO102_2365	COG0360	Binds together with S18 to 16S ribosomal RNA
VCSRO102_2367	COG2906	2 iron, 2 sulfur cluster binding
VCSRO102_2368	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCSRO102_2369	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCSRO102_2370	COG0049	tRNA binding
VCSRO102_2373	COG2923	Belongs to the DsrF TusC family
VCSRO102_2374	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VCSRO102_2375	COG2964	Protein conserved in bacteria
VCSRO102_2376	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO102_2378	COG2900	Belongs to the SlyX family
VCSRO102_2379	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VCSRO102_2380	COG0330	HflC and HflK could
VCSRO102_2381	COG0330	HflC and HflK could
VCSRO102_2382	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VCSRO102_2383	COG1923	regulation of RNA biosynthetic process
VCSRO102_2384	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VCSRO102_2385	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VCSRO102_2386	COG0860	N-Acetylmuramoyl-L-alanine amidase
VCSRO102_2387	COG0802	atpase or kinase
VCSRO102_2388	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VCSRO102_2398	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VCSRO102_2399	COG1162	GTPase activity
VCSRO102_2400	COG0688	phosphatidylethanolamine metabolic process
VCSRO102_2401	COG0471	metal ion transport
VCSRO102_2403	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VCSRO102_2404	COG4942	peptidase
VCSRO102_2407	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VCSRO102_2408	COG2816	NAD+ diphosphatase activity
VCSRO102_2409	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VCSRO102_2410	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VCSRO102_2411	COG0085	RNA polymerase activity
VCSRO102_2412	COG0222	ribosome binding
VCSRO102_2413	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VCSRO102_2415	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VCSRO102_2416	COG0250	Participates in transcription elongation, termination and antitermination
VCSRO102_2417	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCSRO102_2418	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCSRO102_2423	COG1072	(Pantothenic acid kinase))
VCSRO102_2425	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VCSRO102_2427	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VCSRO102_2436	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VCSRO102_2440	COG3118	belongs to the thioredoxin family
VCSRO102_2441	COG0513	Belongs to the DEAD box helicase family
VCSRO102_2442	COG0248	Ppx GppA phosphatase
VCSRO102_2443	COG2205	protein histidine kinase activity
VCSRO102_2443	COG0784	Response regulator, receiver
VCSRO102_2444	COG2814	Major facilitator Superfamily
VCSRO102_2447	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCSRO102_2448	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VCSRO102_2449	COG0511	ligase activity, forming carbon-carbon bonds
VCSRO102_2450	COG0439	Biotin carboxylase
VCSRO102_2451	COG2264	protein methyltransferase activity
VCSRO102_2452	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCSRO102_2453	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VCSRO102_2455	COG0003	Pfam Anion-transporting ATPase
VCSRO102_2459	COG1609	Transcriptional regulator
VCSRO102_2460	COG0129	dihydroxy-acid dehydratase activity
VCSRO102_2461	COG3265	gluconokinase activity
VCSRO102_2463	COG0800	Aldolase
VCSRO102_2466	COG0840	transmembrane signaling receptor activity
VCSRO102_2467	COG1982	Orn Lys Arg decarboxylase major
VCSRO102_2468	COG0531	amino acid
VCSRO102_2469	COG3710	Transcriptional regulator
VCSRO102_2470	COG0789	Transcriptional regulator
VCSRO102_2472	COG0151	Belongs to the GarS family
VCSRO102_2474	COG0776	regulation of translation
VCSRO102_2475	COG1253	flavin adenine dinucleotide binding
VCSRO102_2476	COG1940	carbohydrate kinase activity
VCSRO102_2478	COG3068	Protein conserved in bacteria
VCSRO102_2480	COG1573	uracil-dna glycosylase
VCSRO102_2481	COG0668	transmembrane transport
VCSRO102_2484	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VCSRO102_2485	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCSRO102_2490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCSRO102_2491	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
VCSRO102_2496	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCSRO102_2497	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
VCSRO102_2497	COG0662	Cupin 2, conserved barrel domain protein
VCSRO102_2498	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCSRO102_2503	COG0859	PFAM glycosyl transferase family 9
VCSRO102_2505	COG1519	Transferase
VCSRO102_2511	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
VCSRO102_2511	COG2755	lipolytic protein G-D-S-L family
VCSRO102_2512	COG3642	lipopolysaccharide core region biosynthetic process
VCSRO102_2513	COG0859	PFAM glycosyl transferase family 9
VCSRO102_2514	COG0463	Glycosyl transferase, family 2
VCSRO102_2515	COG0859	PFAM glycosyl transferase family 9
VCSRO102_2516	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VCSRO102_2517	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VCSRO102_2519	COG0267	Belongs to the bacterial ribosomal protein bL33 family
VCSRO102_2520	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VCSRO102_2521	COG2003	Belongs to the UPF0758 family
VCSRO102_2523	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VCSRO102_2524	COG1309	transcriptional regulator
VCSRO102_2525	COG1560	Kdo2-lipid A biosynthetic process
VCSRO102_2526	COG1560	Kdo2-lipid A biosynthetic process
VCSRO102_2527	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VCSRO102_2528	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VCSRO102_2529	COG1561	YicC-like family, N-terminal region
VCSRO102_2530	COG2862	Uncharacterized protein family, UPF0114
VCSRO102_2531	COG1263	PTS System
VCSRO102_2531	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO102_2532	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCSRO102_2536	COG1120	ATPase activity
VCSRO102_2537	COG4774	siderophore transport
VCSRO102_2538	COG1132	(ABC) transporter
VCSRO102_2541	COG0514	ATP-dependent DNA helicase (RecQ)
VCSRO102_2542	COG2962	Rard protein
VCSRO102_2543	COG0405	Gamma-glutamyltransferase
VCSRO102_2545	COG1280	lysine exporter protein (LysE YggA)
VCSRO102_2546	COG0210	DNA helicase
VCSRO102_2548	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VCSRO102_2549	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCSRO102_2552	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO102_2553	COG0601	transmembrane transport
VCSRO102_2554	COG0747	negative chemotaxis
VCSRO102_2563	COG1309	transcriptional regulator
VCSRO102_2564	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCSRO102_2565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO102_2566	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCSRO102_2567	COG2960	long-chain fatty acid transporting porin activity
VCSRO102_2568	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VCSRO102_2569	COG0583	DNA-binding transcription factor activity
VCSRO102_2582	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
VCSRO102_2583	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCSRO102_2584	COG1739	Uncharacterized protein family UPF0029
VCSRO102_2585	COG1024	Enoyl-CoA hydratase
VCSRO102_2585	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCSRO102_2586	COG0183	Belongs to the thiolase family
VCSRO102_2587	COG0583	DNA-binding transcription factor activity
VCSRO102_2588	COG2814	Major facilitator Superfamily
VCSRO102_2590	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VCSRO102_2591	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VCSRO102_2592	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VCSRO102_2593	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VCSRO102_2594	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VCSRO102_2595	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VCSRO102_2597	COG0356	it plays a direct role in the translocation of protons across the membrane
VCSRO102_2598	COG3312	ion transport
VCSRO102_2599	COG1475	DNA binding
VCSRO102_2600	COG1192	Involved in chromosome partitioning
VCSRO102_2601	COG0357	Ribosomal RNA small subunit methyltransferase G
VCSRO102_2602	COG0445	tRNA wobble uridine modification
VCSRO102_2607	COG0217	transcriptional regulatory protein
VCSRO102_2608	COG2084	Dehydrogenase
VCSRO102_2611	COG2909	trisaccharide binding
VCSRO102_2612	COG0058	SHG alpha-glucan phosphorylase activity
VCSRO102_2613	COG0058	SHG alpha-glucan phosphorylase activity
VCSRO102_2614	COG1640	4-alpha-glucanotransferase
VCSRO102_2615	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VCSRO102_2617	COG3501	Rhs element vgr protein
VCSRO102_2618	COG4104	PAAR repeat-containing protein
VCSRO102_2624	COG0471	metal ion transport
VCSRO102_2625	COG3385	transposase activity
VCSRO102_2626	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCSRO102_2634	COG0671	phosphoesterase, PA-phosphatase related
VCSRO102_2636	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VCSRO102_2638	COG1999	signal sequence binding
VCSRO102_2641	COG0786	glutamate:sodium symporter activity
VCSRO102_2648	COG0813	purine-nucleoside phosphorylase activity
VCSRO102_2649	COG3272	Protein of unknown function (DUF1722)
VCSRO102_2651	COG0415	Belongs to the DNA photolyase family
VCSRO102_2652	COG1388	LysM domain
VCSRO102_2652	COG1376	ErfK ybiS ycfS ynhG family protein
VCSRO102_2655	COG0513	Belongs to the DEAD box helicase family
VCSRO102_2656	COG1770	oligopeptidase
VCSRO102_2662	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCSRO102_2663	COG0573	inorganic phosphate transmembrane transporter activity
VCSRO102_2664	COG0581	inorganic phosphate transmembrane transporter activity
VCSRO102_2665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCSRO102_2668	COG3314	Sporulation integral membrane protein YlbJ
VCSRO102_2669	COG0659	secondary active sulfate transmembrane transporter activity
VCSRO102_2671	COG0739	heme binding
VCSRO102_2672	COG5001	Diguanylate cyclase
VCSRO102_2672	COG3300	MHYT domain
VCSRO102_2674	COG0583	DNA-binding transcription factor activity
VCSRO102_2675	COG2814	Major facilitator Superfamily
VCSRO102_2680	COG1301	dicarboxylic acid transport
VCSRO102_2682	COG1342	Belongs to the UPF0251 family
VCSRO102_2688	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VCSRO102_2689	COG0673	inositol 2-dehydrogenase activity
VCSRO102_2691	COG2200	EAL domain
VCSRO102_2691	COG2771	luxR family
VCSRO102_2692	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO102_2694	COG0564	pseudouridine synthase activity
VCSRO102_2707	COG3829	transcription factor binding
VCSRO102_2712	COG3409	Peptidoglycan-binding domain 1 protein
VCSRO102_2712	COG3501	Rhs element vgr protein
VCSRO102_2716	COG1869	D-ribose catabolic process
VCSRO102_2717	COG1129	ABC transporter
VCSRO102_2718	COG1172	Belongs to the binding-protein-dependent transport system permease family
VCSRO102_2719	COG1879	ABC-type sugar transport system periplasmic component
VCSRO102_2720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO102_2721	COG1609	Transcriptional regulator
VCSRO102_2724	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCSRO102_2728	COG0584	glycerophosphoryl diester phosphodiesterase
VCSRO102_2729	COG2271	Major facilitator Superfamily
VCSRO102_2736	COG0579	oxidoreductase
VCSRO102_2738	COG0242	peptide deformylase activity
VCSRO102_2741	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO102_2742	COG1609	Transcriptional regulator
VCSRO102_2743	COG1017	nitric oxide dioxygenase activity
VCSRO102_2743	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCSRO102_2744	COG1320	monovalent cation:proton antiporter activity
VCSRO102_2745	COG2212	antiporter activity
VCSRO102_2746	COG1863	multisubunit Na H antiporter MnhE subunit
VCSRO102_2747	COG0651	ATP synthesis coupled electron transport
VCSRO102_2748	COG1006	Multisubunit Na H antiporter MnhC subunit
VCSRO102_2749	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCSRO102_2749	COG2111	Na H antiporter
VCSRO102_2751	COG0589	response to stress
VCSRO102_2752	COG0814	amino acid
VCSRO102_2755	COG3530	Putative quorum-sensing-regulated virulence factor
VCSRO102_2757	COG5001	Diguanylate cyclase
VCSRO102_2757	COG5002	protein histidine kinase activity
VCSRO102_2758	COG1278	Cold shock
VCSRO102_2761	COG2304	oxidoreductase activity
VCSRO102_2765	COG0714	Associated with various cellular activities
VCSRO102_2766	COG0840	transmembrane signaling receptor activity
VCSRO102_2769	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCSRO102_2770	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCSRO102_2772	COG3604	Transcriptional regulator
VCSRO102_2773	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCSRO102_2773	COG1017	nitric oxide dioxygenase activity
VCSRO102_2774	COG1278	Cold shock
VCSRO102_2775	COG3036	rescue of stalled ribosome
VCSRO102_2780	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VCSRO102_2780	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VCSRO102_2781	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCSRO102_2783	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCSRO102_2785	COG0516	GMP reductase activity
VCSRO102_2786	COG4974	Belongs to the 'phage' integrase family
VCSRO102_2792	COG0513	Belongs to the DEAD box helicase family
VCSRO102_2793	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCSRO102_2794	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VCSRO102_2795	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VCSRO102_2796	COG0784	Response regulator, receiver
VCSRO102_2796	COG3437	response regulator, receiver
VCSRO102_2797	COG4191	Histidine kinase
VCSRO102_2797	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO102_2799	COG1757	Na H antiporter
VCSRO102_2800	COG2814	Major facilitator Superfamily
VCSRO102_2801	COG3240	lipase activity
VCSRO102_2803	COG0840	transmembrane signaling receptor activity
VCSRO102_2804	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VCSRO102_2805	COG5380	lipid catabolic process
VCSRO102_2810	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO102_2811	COG4605	iron ion homeostasis
VCSRO102_2812	COG4604	ABC transporter, ATP-binding protein
VCSRO102_2813	COG2207	Transcriptional regulator
VCSRO102_2816	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCSRO102_2820	COG0745	RESPONSE REGULATOR receiver
VCSRO102_2822	COG3623	hexulose-6-phosphate isomerase
VCSRO102_2823	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
VCSRO102_2824	COG0561	phosphatase activity
VCSRO102_2831	COG0366	Alpha amylase catalytic
VCSRO102_2835	COG0745	RESPONSE REGULATOR receiver
VCSRO102_2836	COG5002	protein histidine kinase activity
VCSRO102_2841	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VCSRO102_2845	COG1686	Belongs to the peptidase S11 family
VCSRO102_2850	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCSRO102_2850	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCSRO102_2851	COG0509	glycine decarboxylation via glycine cleavage system
VCSRO102_2852	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCSRO102_2854	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VCSRO102_2857	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VCSRO102_2858	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
VCSRO102_2859	COG3385	transposase activity
VCSRO102_2870	COG0454	-acetyltransferase
VCSRO102_2887	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO102_2890	COG2161	toxin-antitoxin pair type II binding
VCSRO102_2891	COG4115	mRNA cleavage
VCSRO102_2893	COG1418	mRNA catabolic process
VCSRO102_2907	COG1418	mRNA catabolic process
VCSRO102_2947	COG3549	Plasmid maintenance system killer
VCSRO102_2948	COG3093	addiction module antidote protein HigA
VCSRO102_2965	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
VCSRO102_2971	COG0456	acetyltransferase
VCSRO102_2979	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO102_2994	COG0494	nUDIX hydrolase
VCSRO102_3001	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO102_3056	COG1028	Short-chain dehydrogenase reductase Sdr
VCSRO102_3058	COG0653	protein targeting
VCSRO102_3069	COG5642	Protein of unknown function (DUF2384)
VCSRO102_3074	COG1328	CTP reductase activity
VCSRO102_3075	COG0602	queuosine metabolic process
VCSRO102_3077	COG4067	protein conserved in archaea
VCSRO102_3077	COG0189	ligase activity
VCSRO102_3078	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO102_3078	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCSRO102_3078	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VCSRO102_3079	COG1105	Belongs to the carbohydrate kinase PfkB family
VCSRO102_3080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO102_3080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO102_3081	COG1609	Transcriptional regulator
VCSRO102_3082	COG0420	3'-5' exonuclease activity
VCSRO102_3083	COG0419	ATPase involved in DNA repair
VCSRO102_3084	COG0784	Response regulator, receiver
VCSRO102_3084	COG2205	protein histidine kinase activity
VCSRO102_3085	COG0156	8-amino-7-oxononanoate synthase activity
VCSRO102_3087	COG0038	chloride channel
VCSRO102_3088	COG0523	cobalamin synthesis protein
VCSRO102_3090	COG3158	transport of potassium into the cell
VCSRO102_3091	COG0674	pyruvate-flavodoxin oxidoreductase activity
VCSRO102_3091	COG1013	pyruvate-flavodoxin oxidoreductase activity
VCSRO102_3091	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
VCSRO102_3091	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VCSRO102_3092	COG2205	protein histidine kinase activity
VCSRO102_3093	COG0745	RESPONSE REGULATOR receiver
VCSRO102_3094	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCSRO102_3095	COG0586	Pfam SNARE associated Golgi protein
VCSRO102_3097	COG2200	EAL domain
VCSRO102_3099	COG3038	cytochrome b561
VCSRO102_3101	COG2116	formate transmembrane transporter activity
VCSRO102_3102	COG0583	DNA-binding transcription factor activity
VCSRO102_3104	COG3593	DNA synthesis involved in DNA repair
VCSRO102_3105	COG0737	Belongs to the 5'-nucleotidase family
VCSRO102_3109	COG2824	Alkylphosphonate utilization operon protein PhnA
VCSRO102_3115	COG2199	diguanylate cyclase activity
VCSRO102_3119	COG3706	GGDEF domain
VCSRO102_3122	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VCSRO102_3123	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VCSRO102_3125	COG0745	RESPONSE REGULATOR receiver
VCSRO102_3128	COG3140	Belongs to the UPF0181 family
VCSRO102_3129	COG0023	Translation Initiation Factor
VCSRO102_3133	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO102_3133	COG1042	CoA-binding domain protein
VCSRO102_3133	COG0045	succinate-CoA ligase (ADP-forming) activity
VCSRO102_3134	COG0583	DNA-binding transcription factor activity
VCSRO102_3135	COG4771	TonB-dependent receptor
VCSRO102_3138	COG2050	protein possibly involved in aromatic compounds catabolism
VCSRO102_3142	COG0625	glutathione transferase activity
VCSRO102_3145	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VCSRO102_3146	COG4172	Belongs to the ABC transporter superfamily
VCSRO102_3147	COG4239	(ABC) transporter, permease
VCSRO102_3148	COG4174	ABC transporter (Permease)
VCSRO102_3149	COG4166	transmembrane transport
VCSRO102_3154	COG3104	oligopeptide transport
VCSRO102_3158	COG3842	ATPase activity
VCSRO102_3160	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCSRO102_3161	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VCSRO102_3162	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO102_3163	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCSRO102_3164	COG1011	Hydrolase
VCSRO102_3167	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VCSRO102_3168	COG1970	mechanosensitive ion channel activity
VCSRO102_3169	COG2759	Belongs to the formate--tetrahydrofolate ligase family
VCSRO102_3170	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO102_3170	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCSRO102_3171	COG0302	gtp cyclohydrolase
VCSRO102_3173	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCSRO102_3175	COG2897	thiosulfate sulfurtransferase activity
VCSRO102_3176	COG2390	Transcriptional regulator
VCSRO102_3178	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCSRO102_3183	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCSRO102_3188	COG0583	DNA-binding transcription factor activity
VCSRO102_3189	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
VCSRO102_3197	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCSRO102_3207	COG0745	RESPONSE REGULATOR receiver
VCSRO102_3208	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCSRO102_3208	COG1263	PTS System
VCSRO102_3209	COG1609	Transcriptional regulator
VCSRO102_3210	COG1621	beta-fructofuranosidase activity
VCSRO102_3211	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO102_3212	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCSRO102_3214	COG2885	chlorophyll binding
VCSRO102_3215	COG0545	Peptidyl-prolyl cis-trans isomerase
VCSRO102_3216	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCSRO102_3217	COG0840	transmembrane signaling receptor activity
VCSRO102_3218	COG3069	C4-dicarboxylate transmembrane transporter activity
VCSRO102_3219	COG1760	l-serine dehydratase
VCSRO102_3220	COG2197	response regulator
VCSRO102_3221	COG3850	Histidine kinase
VCSRO102_3222	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCSRO102_3224	COG0243	molybdopterin cofactor binding
VCSRO102_3228	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO102_3229	COG2197	response regulator
VCSRO102_3230	COG3851	Histidine kinase
VCSRO102_3231	COG2271	Major facilitator Superfamily
VCSRO102_3232	COG1840	ABC-type Fe3 transport system, periplasmic component
VCSRO102_3234	COG3842	ATPase activity
VCSRO102_3235	COG3243	poly(R)-hydroxyalkanoic acid synthase
VCSRO102_3237	COG0183	Belongs to the thiolase family
VCSRO102_3239	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO102_3240	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCSRO102_3244	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCSRO102_3246	COG1979	alcohol dehydrogenase
VCSRO102_3249	COG4191	Histidine kinase
VCSRO102_3252	COG2271	Major facilitator Superfamily
VCSRO102_3253	COG0469	pyruvate kinase activity
VCSRO102_3255	COG1879	ABC-type sugar transport system periplasmic component
VCSRO102_3256	COG1803	Methylglyoxal synthase
VCSRO102_3257	COG1335	isochorismatase
VCSRO102_3258	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VCSRO102_3261	COG0210	DNA helicase
VCSRO102_3262	COG1289	transmembrane transporter activity
VCSRO102_3268	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
VCSRO102_3269	COG4149	molybdate abc transporter
VCSRO102_3270	COG0725	ABC transporter, periplasmic molybdate-binding protein
VCSRO102_3271	COG1492	cobalamin metabolic process
VCSRO102_3278	COG0784	Response regulator, receiver
VCSRO102_3278	COG5002	protein histidine kinase activity
VCSRO102_3279	COG1879	ABC-type sugar transport system periplasmic component
VCSRO102_3281	COG2827	Endonuclease containing a URI domain
VCSRO102_3284	COG2926	Belongs to the UPF0265 family
VCSRO102_3287	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
VCSRO102_3288	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VCSRO102_3289	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCSRO102_3290	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
VCSRO102_3291	COG0247	lactate metabolic process
VCSRO102_3292	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCSRO102_3293	COG3118	belongs to the thioredoxin family
VCSRO102_3298	COG4160	amino acid transport
VCSRO102_3299	COG4215	(ABC) transporter
VCSRO102_3300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO102_3301	COG1126	abc transporter atp-binding protein
VCSRO102_3303	COG2425	protein containing a von Willebrand factor type A (vWA) domain
VCSRO102_3305	COG0494	nUDIX hydrolase
VCSRO102_3306	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VCSRO102_3308	COG1309	transcriptional regulator
VCSRO102_3309	COG0513	Belongs to the DEAD box helicase family
VCSRO102_3310	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
VCSRO102_3312	COG0814	amino acid
VCSRO102_3313	COG0840	transmembrane signaling receptor activity
VCSRO102_3314	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VCSRO102_3315	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
VCSRO102_3317	COG1984	allophanate hydrolase subunit 2
VCSRO102_3320	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VCSRO102_3321	COG4181	ATPase activity
VCSRO102_3323	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCSRO102_3324	COG1716	ATPase activity
VCSRO102_3324	COG5001	Diguanylate cyclase
VCSRO102_3326	COG0484	heat shock protein binding
VCSRO102_3336	COG0546	phosphoglycolate phosphatase activity
VCSRO102_3339	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCSRO102_3340	COG1368	sulfuric ester hydrolase activity
VCSRO102_3342	COG0513	Belongs to the DEAD box helicase family
VCSRO102_3345	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCSRO102_3347	COG3046	protein related to deoxyribodipyrimidine photolyase
VCSRO102_3348	COG3397	chitin binding
VCSRO102_3349	COG3227	Zinc metalloprotease (Elastase)
VCSRO102_3351	COG0010	Belongs to the arginase family
VCSRO102_3352	COG1166	arginine decarboxylase activity
VCSRO102_3354	COG2239	Acts as a magnesium transporter
VCSRO102_3355	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCSRO102_3356	COG0459	protein refolding
VCSRO102_3358	COG0527	aspartate kinase activity
VCSRO102_3359	COG0662	Cupin 2, conserved barrel domain protein
VCSRO102_3360	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VCSRO102_3361	COG0456	acetyltransferase
VCSRO102_3362	COG2154	pterin-4-alpha-carbinolamine dehydratase
VCSRO102_3363	COG3186	Phenylalanine-4-hydroxylase
VCSRO102_3364	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCSRO102_3368	COG2264	protein methyltransferase activity
VCSRO102_3372	COG2171	N-acyltransferase activity
VCSRO102_3373	COG1253	flavin adenine dinucleotide binding
VCSRO102_3374	COG1765	OsmC-like protein
VCSRO102_3379	COG0531	amino acid
VCSRO102_3382	COG3279	Response regulator of the LytR AlgR family
VCSRO102_3383	COG3275	phosphorelay sensor kinase activity
VCSRO102_3386	COG1136	(ABC) transporter
VCSRO102_3386	COG0577	efflux transmembrane transporter activity
VCSRO102_3387	COG1136	(ABC) transporter
VCSRO102_3389	COG4989	oxidoreductase activity
VCSRO102_3390	COG0366	Alpha amylase catalytic
VCSRO102_3391	COG2067	long-chain fatty acid transport protein
VCSRO102_3392	COG2267	carboxylic ester hydrolase activity
VCSRO102_3394	COG3227	Zinc metalloprotease (Elastase)
VCSRO102_3395	COG3047	cAMP biosynthetic process
VCSRO102_3398	COG1686	Belongs to the peptidase S11 family
VCSRO102_3399	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VCSRO102_3400	COG1271	oxidase subunit
VCSRO102_3401	COG1294	oxidase, subunit
VCSRO102_3404	COG3048	D-serine ammonia-lyase activity
VCSRO102_3405	COG0583	DNA-binding transcription factor activity
VCSRO102_3407	COG0582	viral genome integration into host DNA
VCSRO102_3410	COG1063	alcohol dehydrogenase
VCSRO102_3416	COG0346	lactoylglutathione lyase activity
VCSRO102_3420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
VCSRO102_3421	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO102_3422	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VCSRO102_3423	COG0363	glucosamine-6-phosphate deaminase activity
VCSRO102_3424	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VCSRO102_3429	COG1929	Belongs to the glycerate kinase type-1 family
VCSRO102_3430	COG2610	gluconate transmembrane transporter activity
VCSRO102_3431	COG3835	regulator
VCSRO102_3433	COG0748	coenzyme F420 binding
VCSRO102_3434	COG3721	Heme iron utilization protein
VCSRO102_3436	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCSRO102_3437	COG0811	peptide transport
VCSRO102_3438	COG0848	biopolymer transport protein
VCSRO102_3439	COG4558	Periplasmic binding protein
VCSRO102_3440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCSRO102_3441	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VCSRO102_3448	COG3217	Mosc domain protein beta barrel domain protein
VCSRO102_3448	COG3217	Mosc domain protein beta barrel domain protein
VCSRO102_3448	COG0633	Ferredoxin
VCSRO102_3448	COG0633	Ferredoxin
VCSRO102_3449	COG0418	dihydroorotase activity
VCSRO102_3451	COG3152	Membrane
VCSRO102_3453	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCSRO102_3454	COG2354	Protein conserved in bacteria
VCSRO102_3455	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCSRO102_3456	COG1278	Cold shock
VCSRO102_3461	COG2199	diguanylate cyclase activity
VCSRO102_3462	COG1349	DNA-binding transcription factor activity
VCSRO102_3465	COG3833	ABC-type maltose transport systems, permease component
VCSRO102_3466	COG1175	transmembrane transport
VCSRO102_3468	COG3842	ATPase activity
VCSRO102_3469	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCSRO102_3472	COG0393	Putative heavy-metal-binding
VCSRO102_3474	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCSRO102_3475	COG0784	Response regulator, receiver
VCSRO102_3475	COG0835	chemotaxis
VCSRO102_3476	COG1846	Transcriptional regulator
VCSRO102_3477	COG3706	GGDEF domain
VCSRO102_3484	COG0583	DNA-binding transcription factor activity
VCSRO102_3485	COG5001	Diguanylate cyclase
VCSRO102_3487	COG1741	Belongs to the pirin family
VCSRO102_3488	COG3123	guanosine phosphorylase activity
VCSRO102_3490	COG2211	Major facilitator Superfamily
VCSRO102_3492	COG0840	transmembrane signaling receptor activity
VCSRO102_3493	COG1067	ATP-dependent peptidase activity
VCSRO102_3495	COG4172	Belongs to the ABC transporter superfamily
VCSRO102_3499	COG0583	DNA-binding transcription factor activity
VCSRO102_3500	COG1620	l-lactate permease
VCSRO102_3503	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
VCSRO102_3505	COG0840	transmembrane signaling receptor activity
VCSRO102_3507	COG1472	Belongs to the glycosyl hydrolase 3 family
VCSRO102_3509	COG4580	involved in the transport of maltose and maltodextrins
VCSRO102_3512	COG1609	Transcriptional regulator
VCSRO102_3514	COG4608	Belongs to the ABC transporter superfamily
VCSRO102_3515	COG0444	Belongs to the ABC transporter superfamily
VCSRO102_3516	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO102_3520	COG0513	Belongs to the DEAD box helicase family
VCSRO102_3521	COG0583	DNA-binding transcription factor activity
VCSRO102_3523	COG1902	pentaerythritol trinitrate reductase activity
VCSRO102_3525	COG1132	(ABC) transporter
VCSRO102_3527	COG1902	pentaerythritol trinitrate reductase activity
VCSRO102_3529	COG1280	lysine exporter protein (LysE YggA)
VCSRO102_3530	COG2207	Transcriptional regulator
VCSRO102_3534	COG1846	Transcriptional regulator
VCSRO102_3535	COG1764	response to oxidative stress
VCSRO102_3536	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCSRO102_3537	COG0697	spore germination
VCSRO102_3539	COG0700	Nucleoside recognition
VCSRO102_3540	COG3366	ferrous iron transmembrane transporter activity
VCSRO102_3541	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
VCSRO102_3542	COG4565	transcriptional regulatory protein
VCSRO102_3544	COG0471	metal ion transport
VCSRO102_3546	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VCSRO102_3547	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
VCSRO102_3548	COG2259	Doxx family
VCSRO102_3553	COG0363	glucosamine-6-phosphate deaminase activity
VCSRO102_3556	COG4580	involved in the transport of maltose and maltodextrins
VCSRO102_3559	COG0840	transmembrane signaling receptor activity
VCSRO102_3562	COG0840	transmembrane signaling receptor activity
VCSRO102_3564	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCSRO102_3565	COG1126	abc transporter atp-binding protein
VCSRO102_3567	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCSRO102_3568	COG4597	amino acid ABC transporter
VCSRO102_3569	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCSRO102_3570	COG2213	PTS system mannitol-specific
VCSRO102_3570	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCSRO102_3571	COG0246	Mannitol dehydrogenase
VCSRO102_3572	COG3722	fumarate hydratase activity
VCSRO102_3573	COG0673	inositol 2-dehydrogenase activity
VCSRO102_3578	COG0697	spore germination
VCSRO102_3581	COG1335	isochorismatase
VCSRO102_3583	COG2910	NAD(P)H-binding
VCSRO102_3585	COG0840	transmembrane signaling receptor activity
VCSRO102_3586	COG4221	oxidoreductase activity
VCSRO102_3589	COG1901	pseudouridine methyltransferase
VCSRO102_3591	COG0531	amino acid
VCSRO102_3592	COG1982	Orn Lys Arg decarboxylase major
VCSRO102_3597	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCSRO102_3602	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VCSRO102_3610	COG0745	RESPONSE REGULATOR receiver
VCSRO102_3615	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCSRO102_3616	COG0840	transmembrane signaling receptor activity
VCSRO102_3617	COG0835	chemotaxis
VCSRO102_3618	COG0835	chemotaxis
VCSRO102_3619	COG0643	Histidine kinase
VCSRO102_3619	COG2198	Histidine kinase
VCSRO102_3623	COG0601	transmembrane transport
VCSRO102_3624	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCSRO102_3627	COG2194	sulfuric ester hydrolase activity
VCSRO102_3628	COG0642	Histidine kinase
VCSRO102_3631	COG4221	oxidoreductase activity
VCSRO102_3635	COG1444	tRNA N-acetyltransferase activity
VCSRO102_3636	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine