locus-tag	class	description
G3U99_00025	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G3U99_00035	COG1677	Flagellar hook-basal body complex protein FliE
G3U99_00045	COG4191	Histidine kinase
G3U99_00055	COG1516	flagellar protein fliS
G3U99_00065	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G3U99_00075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G3U99_00090	COG2837	iron assimilation
G3U99_00100	COG4235	cytochrome complex assembly
G3U99_00100	COG3088	subunit of a heme lyase
G3U99_00105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G3U99_00110	COG1138	Cytochrome C-type biogenesis protein
G3U99_00115	COG3301	Polysulphide reductase, NrfD
G3U99_00120	COG0437	4 iron, 4 sulfur cluster binding
G3U99_00125	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
G3U99_00130	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
G3U99_00155	COG1393	Belongs to the ArsC family
G3U99_00160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3U99_00175	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
G3U99_00185	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G3U99_00185	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G3U99_00200	COG1611	Belongs to the LOG family
G3U99_00205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3U99_00230	COG0583	DNA-binding transcription factor activity
G3U99_00235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G3U99_00235	COG0301	tRNA thio-modification
G3U99_00245	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G3U99_00255	COG0142	geranyltranstransferase activity
G3U99_00265	COG0564	pseudouridine synthase activity
G3U99_00270	COG3098	single-species biofilm formation
G3U99_00305	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3U99_00310	COG0567	Dehydrogenase, E1 component
G3U99_00315	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G3U99_00320	COG1053	succinate dehydrogenase
G3U99_00325	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G3U99_00340	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G3U99_00350	COG0033	Phosphoglucomutase
G3U99_00355	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
G3U99_00360	COG0596	Alpha beta hydrolase
G3U99_00370	COG0716	FMN binding
G3U99_00390	COG1263	PTS System
G3U99_00390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G3U99_00390	COG2190	(PTS) system
G3U99_00395	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G3U99_00400	COG1940	carbohydrate kinase activity
G3U99_00400	COG1846	Transcriptional regulator
G3U99_00405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G3U99_00405	COG4651	solute:proton antiporter activity
G3U99_00410	COG0367	asparagine synthase
G3U99_00415	COG3104	oligopeptide transport
G3U99_00440	COG2840	Smr protein MutS2
G3U99_00445	COG1187	pseudouridine synthase activity
G3U99_00450	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G3U99_00455	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G3U99_00460	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G3U99_00485	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G3U99_00485	COG0047	phosphoribosylformylglycinamidine synthase activity
G3U99_00490	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G3U99_00500	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
G3U99_00520	COG4970	Tfp pilus assembly protein FimT
G3U99_00535	COG0443	Heat shock 70 kDa protein
G3U99_00540	COG1301	dicarboxylic acid transport
G3U99_00545	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G3U99_00560	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3U99_00565	COG2914	Belongs to the UPF0125 (RnfH) family
G3U99_00570	COG2867	negative regulation of translational initiation
G3U99_00595	COG0668	transmembrane transport
G3U99_00600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G3U99_00620	COG0204	Acyl-transferase
G3U99_00625	COG0835	chemotaxis
G3U99_00625	COG0784	Response regulator, receiver
G3U99_00630	COG2873	o-acetylhomoserine
G3U99_00650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3U99_00655	COG1115	amino acid carrier protein
G3U99_00660	COG1584	GPR1 FUN34 yaaH family protein
G3U99_00675	COG0516	GMP reductase activity
G3U99_00675	COG0517	IMP dehydrogenase activity
G3U99_00690	COG2203	Gaf domain
G3U99_00690	COG2199	diguanylate cyclase activity
G3U99_00700	COG1160	GTP binding
G3U99_00705	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3U99_00710	COG2976	Protein conserved in bacteria
G3U99_00715	COG0124	histidyl-tRNA synthetase
G3U99_00720	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G3U99_00725	COG1426	Protein conserved in bacteria
G3U99_00735	COG2166	iron-sulfur cluster assembly
G3U99_00740	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G3U99_00745	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
G3U99_00765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G3U99_00770	COG1074	ATP-dependent DNA helicase activity
G3U99_00775	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G3U99_00795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_00800	COG1309	transcriptional regulator
G3U99_00805	COG3141	response to X-ray
G3U99_00820	COG0704	Plays a role in the regulation of phosphate uptake
G3U99_00825	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G3U99_00830	COG0581	inorganic phosphate transmembrane transporter activity
G3U99_00840	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G3U99_00845	COG0248	Ppx GppA phosphatase
G3U99_00855	COG5002	protein histidine kinase activity
G3U99_00860	COG0745	RESPONSE REGULATOR receiver
G3U99_00875	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G3U99_00895	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3U99_00900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3U99_00905	COG1862	Preprotein translocase
G3U99_00915	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G3U99_00920	COG0517	IMP dehydrogenase activity
G3U99_00930	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G3U99_00935	COG0583	DNA-binding transcription factor activity
G3U99_00940	COG0450	alkyl hydroperoxide reductase
G3U99_00945	COG2171	N-acyltransferase activity
G3U99_00955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3U99_00965	COG2207	Transcriptional regulator
G3U99_00970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3U99_00970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3U99_00970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3U99_00985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3U99_00995	COG2017	converts alpha-aldose to the beta-anomer
G3U99_01005	COG1085	galactose-1-phosphate uridylyltransferase
G3U99_01010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G3U99_01015	COG1609	Transcriptional regulator
G3U99_01020	COG3250	beta-galactosidase activity
G3U99_01025	COG2731	YhcH YjgK YiaL family protein
G3U99_01030	COG0531	amino acid
G3U99_01035	COG1309	transcriptional regulator
G3U99_01050	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
G3U99_01050	COG3408	Glycogen debranching enzyme
G3U99_01060	COG2211	Major facilitator Superfamily
G3U99_01065	COG1486	melibiose metabolic process
G3U99_01070	COG2169	Transcriptional regulator
G3U99_01135	COG4964	Belongs to the GSP D family
G3U99_01165	COG2169	Transcriptional regulator
G3U99_01170	COG1022	Amp-dependent synthetase and ligase
G3U99_01175	COG0583	DNA-binding transcription factor activity
G3U99_01185	COG0583	DNA-binding transcription factor activity
G3U99_01190	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G3U99_01200	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G3U99_01205	COG2975	iron-sulfur cluster assembly
G3U99_01210	COG0633	Ferredoxin
G3U99_01215	COG0443	Heat shock 70 kDa protein
G3U99_01230	COG0822	iron-sulfur transferase activity
G3U99_01235	COG1104	cysteine desulfurase activity
G3U99_01250	COG0483	inositol monophosphate 1-phosphatase activity
G3U99_01290	COG0542	response to heat
G3U99_01300	COG0564	pseudouridine synthase activity
G3U99_01305	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3U99_01310	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G3U99_01315	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G3U99_01320	COG0077	Prephenate dehydratase
G3U99_01320	COG1605	Chorismate mutase
G3U99_01325	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G3U99_01330	COG5001	Diguanylate cyclase
G3U99_01335	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
G3U99_01340	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
G3U99_01350	COG0488	(ABC) transporter
G3U99_01360	COG0739	heme binding
G3U99_01365	COG0287	Prephenate dehydrogenase
G3U99_01365	COG1605	Chorismate mutase
G3U99_01370	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G3U99_01375	COG3275	phosphorelay sensor kinase activity
G3U99_01380	COG3279	Response regulator of the LytR AlgR family
G3U99_01390	COG1737	Transcriptional regulator
G3U99_01405	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G3U99_01410	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G3U99_01420	COG1966	Carbon starvation protein
G3U99_01425	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G3U99_01430	COG1047	Peptidyl-prolyl cis-trans
G3U99_01445	COG0196	riboflavin kinase activity
G3U99_01450	COG0728	peptidoglycan biosynthetic process
G3U99_01455	COG0268	Binds directly to 16S ribosomal RNA
G3U99_01460	COG0640	Transcriptional regulator
G3U99_01465	COG0583	DNA-binding transcription factor activity
G3U99_01470	COG1283	sodium-dependent phosphate transmembrane transporter activity
G3U99_01475	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G3U99_01485	COG0730	response to heat
G3U99_01500	COG3066	DNA modification
G3U99_01510	COG0667	Aldo Keto reductase
G3U99_01520	COG2204	response regulator
G3U99_01525	COG0534	Mate efflux family protein
G3U99_01530	COG1846	Transcriptional regulator
G3U99_01545	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G3U99_01555	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G3U99_01560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G3U99_01565	COG2860	membrane
G3U99_01570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G3U99_01575	COG0083	homoserine kinase activity
G3U99_01595	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3U99_01605	COG0745	RESPONSE REGULATOR receiver
G3U99_01615	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G3U99_01625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3U99_01630	COG3025	triphosphatase activity
G3U99_01635	COG1392	Phosphate transport regulator
G3U99_01640	COG0306	phosphate transporter
G3U99_01645	COG4991	sh3 domain protein
G3U99_01655	COG3409	Peptidoglycan-binding domain 1 protein
G3U99_01655	COG3267	Type II secretory pathway component ExeA
G3U99_01660	COG0617	tRNA 3'-terminal CCA addition
G3U99_01665	COG0148	phosphopyruvate hydratase activity
G3U99_01675	COG3956	TIGRFAM MazG family protein
G3U99_01680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3U99_01685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G3U99_01690	COG2205	protein histidine kinase activity
G3U99_01690	COG4999	Histidine kinase
G3U99_01690	COG3437	response regulator, receiver
G3U99_01690	COG3850	Histidine kinase
G3U99_01695	COG0736	holo-[acyl-carrier-protein] synthase activity
G3U99_01700	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G3U99_01705	COG1381	Involved in DNA repair and RecF pathway recombination
G3U99_01710	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G3U99_01725	COG0481	GTPase activity
G3U99_01730	COG3086	response to oxidative stress
G3U99_01735	COG3026	antisigma factor binding
G3U99_01745	COG1595	DNA-templated transcription, initiation
G3U99_01750	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G3U99_01775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3U99_01780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3U99_01790	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
G3U99_01800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G3U99_01810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3U99_01815	COG2271	Major facilitator Superfamily
G3U99_01820	COG0584	glycerophosphoryl diester phosphodiesterase
G3U99_01825	COG0440	acetolactate synthase activity
G3U99_01830	COG0028	Belongs to the TPP enzyme family
G3U99_01835	COG1022	Amp-dependent synthetase and ligase
G3U99_01840	COG0583	DNA-binding transcription factor activity
G3U99_01860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3U99_01865	COG0473	3-isopropylmalate dehydrogenase activity
G3U99_01925	COG3437	response regulator, receiver
G3U99_01945	COG1854	S-ribosylhomocysteine lyase activity
G3U99_01955	COG2918	glutathione biosynthetic process
G3U99_01960	COG0612	Peptidase, M16
G3U99_01965	COG1238	metal cluster binding
G3U99_01970	COG2130	NADP-dependent
G3U99_01975	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
G3U99_01980	COG5016	pyruvate
G3U99_01980	COG0511	ligase activity, forming carbon-carbon bonds
G3U99_01985	COG3630	sodium ion export across plasma membrane
G3U99_02035	COG0527	aspartate kinase activity
G3U99_02045	COG2137	regulation of response to DNA damage stimulus
G3U99_02050	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G3U99_02055	COG1546	Belongs to the CinA family
G3U99_02085	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G3U99_02090	COG0795	lipopolysaccharide-transporting ATPase activity
G3U99_02095	COG0795	lipopolysaccharide-transporting ATPase activity
G3U99_02105	COG2927	DNA polymerase III (CHI subunit)
G3U99_02110	COG0525	valine-tRNA ligase activity
G3U99_02120	COG4269	membrane
G3U99_02130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3U99_02135	COG0564	pseudouridine synthase activity
G3U99_02145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G3U99_02150	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G3U99_02165	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
G3U99_02170	COG0251	oxidation-reduction process
G3U99_02180	COG0039	L-malate dehydrogenase activity
G3U99_02190	COG2358	TRAP transporter, solute receptor (TAXI family
G3U99_02200	COG0589	response to stress
G3U99_02220	COG2235	arginine
G3U99_02225	COG0204	Acyl-transferase
G3U99_02235	COG5007	Belongs to the BolA IbaG family
G3U99_02245	COG2854	intermembrane phospholipid transfer
G3U99_02250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G3U99_02255	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G3U99_02260	COG1127	ABC transporter
G3U99_02270	COG0517	IMP dehydrogenase activity
G3U99_02270	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G3U99_02275	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G3U99_02285	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G3U99_02290	COG1137	ATPase activity
G3U99_02300	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G3U99_02305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3U99_02310	COG1660	Displays ATPase and GTPase activities
G3U99_02315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3U99_02320	COG2239	Acts as a magnesium transporter
G3U99_02325	COG1410	methionine synthase
G3U99_02325	COG0646	methionine synthase
G3U99_02385	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3U99_02390	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G3U99_02535	COG3437	response regulator, receiver
G3U99_02540	COG5002	protein histidine kinase activity
G3U99_02540	COG2205	protein histidine kinase activity
G3U99_02540	COG0784	Response regulator, receiver
G3U99_02545	COG0735	belongs to the Fur family
G3U99_02555	COG0529	Catalyzes the synthesis of activated sulfate
G3U99_02560	COG0471	metal ion transport
G3U99_02560	COG3273	potassium ion transport
G3U99_02575	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G3U99_02575	COG1648	precorrin-2 dehydrogenase activity
G3U99_02580	COG0737	Belongs to the 5'-nucleotidase family
G3U99_02590	COG2153	protein acetylation
G3U99_02605	COG0545	Peptidyl-prolyl cis-trans isomerase
G3U99_02615	COG0203	ribosomal protein L17
G3U99_02630	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G3U99_02635	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G3U99_02640	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G3U99_02645	COG0201	protein transport
G3U99_02655	COG1841	ribosomal large subunit assembly
G3U99_02670	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G3U99_02685	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G3U99_02700	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G3U99_02715	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G3U99_02720	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G3U99_02725	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G3U99_02740	COG0088	Forms part of the polypeptide exit tunnel
G3U99_02750	COG0051	transcription antitermination factor activity, RNA binding
G3U99_02755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G3U99_02760	COG0557	exoribonuclease II activity
G3U99_02765	COG0402	S-adenosylhomocysteine deaminase activity
G3U99_02770	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
G3U99_02775	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G3U99_02785	COG1047	Peptidyl-prolyl cis-trans
G3U99_02800	COG2249	NAD(P)H dehydrogenase (quinone) activity
G3U99_02805	COG0488	(ABC) transporter
G3U99_02815	COG0429	hydrolase of the alpha beta-hydrolase fold
G3U99_02825	COG3954	Phosphoribulokinase
G3U99_02830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3U99_02850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G3U99_02890	COG1027	Aspartate ammonia-lyase
G3U99_02895	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
G3U99_02900	COG1288	antiporter activity
G3U99_02915	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G3U99_02920	COG0540	Belongs to the ATCase OTCase family
G3U99_02925	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
G3U99_02930	COG1438	arginine binding
G3U99_02935	COG4232	protein-disulfide reductase activity
G3U99_02945	COG2095	MarC family integral membrane protein
G3U99_02955	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3U99_02965	COG2205	protein histidine kinase activity
G3U99_02965	COG0784	Response regulator, receiver
G3U99_02970	COG2814	Major facilitator Superfamily
G3U99_02985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3U99_02990	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G3U99_02995	COG0511	ligase activity, forming carbon-carbon bonds
G3U99_03000	COG0439	Biotin carboxylase
G3U99_03005	COG2264	protein methyltransferase activity
G3U99_03010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G3U99_03015	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G3U99_03050	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G3U99_03065	COG3706	GGDEF domain
G3U99_03070	COG0789	Transcriptional regulator
G3U99_03080	COG0151	Belongs to the GarS family
G3U99_03095	COG1253	flavin adenine dinucleotide binding
G3U99_03105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3U99_03110	COG1573	uracil-dna glycosylase
G3U99_03115	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G3U99_03120	COG1695	Transcriptional regulator
G3U99_03125	COG1045	serine acetyltransferase
G3U99_03140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G3U99_03175	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3U99_03180	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
G3U99_03185	COG1053	succinate dehydrogenase
G3U99_03190	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G3U99_03220	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G3U99_03225	COG1609	Transcriptional regulator
G3U99_03230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G3U99_03240	COG0281	malic enzyme
G3U99_03250	COG0626	cystathionine gamma-synthase activity
G3U99_03255	COG0527	aspartate kinase activity
G3U99_03255	COG0460	homoserine dehydrogenase
G3U99_03260	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G3U99_03270	COG1494	fructose-1,6-bisphosphatase
G3U99_03310	COG0438	transferase activity, transferring glycosyl groups
G3U99_03320	COG0463	Glycosyl transferase, family 2
G3U99_03350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G3U99_03360	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
G3U99_03365	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
G3U99_03400	COG1086	Polysaccharide biosynthesis protein
G3U99_03410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G3U99_03415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3U99_03420	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
G3U99_03420	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
G3U99_03425	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G3U99_03435	COG0438	transferase activity, transferring glycosyl groups
G3U99_03455	COG0859	PFAM glycosyl transferase family 9
G3U99_03470	COG1519	Transferase
G3U99_03485	COG3642	lipopolysaccharide core region biosynthetic process
G3U99_03490	COG0859	PFAM glycosyl transferase family 9
G3U99_03495	COG0463	Glycosyl transferase, family 2
G3U99_03500	COG0859	PFAM glycosyl transferase family 9
G3U99_03505	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G3U99_03535	COG2003	Belongs to the UPF0758 family
G3U99_03540	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G3U99_03545	COG1309	transcriptional regulator
G3U99_03550	COG1560	Kdo2-lipid A biosynthetic process
G3U99_03555	COG1560	Kdo2-lipid A biosynthetic process
G3U99_03560	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G3U99_03565	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G3U99_03570	COG1561	YicC-like family, N-terminal region
G3U99_03575	COG2252	PERMEase
G3U99_03585	COG0848	biopolymer transport protein
G3U99_03605	COG4206	TonB-dependent receptor
G3U99_03605	COG1629	transport
G3U99_03615	COG1595	DNA-templated transcription, initiation
G3U99_03620	COG0194	GDP metabolic process
G3U99_03625	COG1758	RNA polymerase activity
G3U99_03630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3U99_03635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G3U99_03640	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G3U99_03645	COG1218	3'(2'),5'-bisphosphate nucleotidase
G3U99_03650	COG0494	nUDIX hydrolase
G3U99_03655	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G3U99_03655	COG0316	Belongs to the HesB IscA family
G3U99_03665	COG0596	Alpha beta hydrolase
G3U99_03675	COG2183	response to ionizing radiation
G3U99_03685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3U99_03690	COG0745	RESPONSE REGULATOR receiver
G3U99_03705	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
G3U99_03710	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
G3U99_03715	COG3156	type II secretion system protein K
G3U99_03720	COG4795	General secretion pathway protein
G3U99_03725	COG2165	general secretion pathway protein
G3U99_03730	COG2165	general secretion pathway protein
G3U99_03735	COG2165	general secretion pathway protein
G3U99_03740	COG1459	type II secretion system
G3U99_03745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G3U99_03755	COG3031	protein transport across the cell outer membrane
G3U99_03760	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G3U99_03770	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
G3U99_03780	COG0456	acetyltransferase
G3U99_03785	COG1490	D-aminoacyl-tRNA deacylase activity
G3U99_03805	COG0174	glutamine synthetase
G3U99_03810	COG3852	Histidine kinase
G3U99_03815	COG2204	response regulator
G3U99_03825	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3U99_03865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G3U99_03880	COG0408	coproporphyrinogen oxidase activity
G3U99_03890	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G3U99_03895	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G3U99_03900	COG0551	DNA topoisomerase type I activity
G3U99_03905	COG2922	Belongs to the Smg family
G3U99_03910	COG0758	DNA mediated transformation
G3U99_03915	COG0242	peptide deformylase activity
G3U99_03925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G3U99_03925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G3U99_03930	COG0569	domain protein
G3U99_03935	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G3U99_03945	COG1272	protein, Hemolysin III
G3U99_03950	COG4326	sporulation control protein
G3U99_03955	COG3084	Protein conserved in bacteria
G3U99_03965	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G3U99_03970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G3U99_03975	COG0204	Acyl-transferase
G3U99_03985	COG0606	chelatase, subunit chli
G3U99_03995	COG3978	acetolactate synthase activity
G3U99_04000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G3U99_04005	COG0129	dihydroxy-acid dehydratase activity
G3U99_04015	COG0604	alcohol dehydrogenase
G3U99_04030	COG0425	Belongs to the sulfur carrier protein TusA family
G3U99_04040	COG2119	membrane
G3U99_04050	COG0751	glycine-tRNA ligase activity
G3U99_04055	COG3977	Valine--pyruvate aminotransferase
G3U99_04060	COG0071	Belongs to the small heat shock protein (HSP20) family
G3U99_04065	COG0187	DNA topoisomerase II activity
G3U99_04070	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G3U99_04075	COG0592	DNA-directed DNA polymerase activity
G3U99_04095	COG1126	abc transporter atp-binding protein
G3U99_04115	COG0706	membrane insertase activity
G3U99_04120	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G3U99_04125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G3U99_04130	COG0445	tRNA wobble uridine modification
G3U99_04140	COG1192	Involved in chromosome partitioning
G3U99_04145	COG1475	DNA binding
G3U99_04150	COG3312	ion transport
G3U99_04170	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G3U99_04175	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G3U99_04180	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G3U99_04185	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G3U99_04190	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G3U99_04200	COG0765	amino acid transport
G3U99_04210	COG2814	Major facilitator Superfamily
G3U99_04215	COG0583	DNA-binding transcription factor activity
G3U99_04220	COG3706	GGDEF domain
G3U99_04235	COG1739	Uncharacterized protein family UPF0029
G3U99_04240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G3U99_04295	COG2132	Multicopper oxidase
G3U99_04310	COG0352	thiamine-phosphate diphosphorylase activity
G3U99_04315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G3U99_04325	COG2022	thiamine diphosphate biosynthetic process
G3U99_04335	COG0006	proline dipeptidase activity
G3U99_04335	COG0006	proline dipeptidase activity
G3U99_04355	COG1522	sequence-specific DNA binding
G3U99_04360	COG5001	Diguanylate cyclase
G3U99_04360	COG5002	protein histidine kinase activity
G3U99_04365	COG0742	ribosomal rna small subunit methyltransferase
G3U99_04380	COG0589	response to stress
G3U99_04385	COG1528	Iron-storage protein
G3U99_04395	COG2081	HI0933 family
G3U99_04425	COG1639	'signal transduction protein
G3U99_04435	COG1322	Protein conserved in bacteria
G3U99_04440	COG2226	methyltransferase
G3U99_04460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G3U99_04465	COG0805	protein transport
G3U99_04470	COG0084	hydrolase, TatD family'
G3U99_04485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3U99_04485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3U99_04515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G3U99_04520	COG0583	DNA-binding transcription factor activity
G3U99_04525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G3U99_04530	COG2960	long-chain fatty acid transporting porin activity
G3U99_04535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3U99_04540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_04545	COG1309	transcriptional regulator
G3U99_04590	COG0747	negative chemotaxis
G3U99_04600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3U99_04615	COG0745	RESPONSE REGULATOR receiver
G3U99_04635	COG0477	Major facilitator Superfamily
G3U99_04650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3U99_04655	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G3U99_04675	COG3220	belongs to the UPF0276 family
G3U99_04685	COG0210	DNA helicase
G3U99_04700	COG0405	Gamma-glutamyltransferase
G3U99_04705	COG1280	lysine exporter protein (LysE YggA)
G3U99_04715	COG2962	Rard protein
G3U99_04720	COG0514	ATP-dependent DNA helicase (RecQ)
G3U99_04730	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G3U99_04735	COG0248	Ppx GppA phosphatase
G3U99_04745	COG3118	belongs to the thioredoxin family
G3U99_04760	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G3U99_04820	COG3071	HemY protein
G3U99_04825	COG2959	enzyme of heme biosynthesis
G3U99_04830	COG1587	Uroporphyrinogen-III synthase
G3U99_04840	COG3072	Adenylate cyclase
G3U99_04845	COG1965	Belongs to the frataxin family
G3U99_04855	COG0019	diaminopimelate decarboxylase activity
G3U99_04860	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G3U99_04870	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G3U99_04875	COG1011	Hydrolase
G3U99_04880	COG3287	FIST C domain
G3U99_04880	COG2199	diguanylate cyclase activity
G3U99_04880	COG2200	EAL domain
G3U99_04900	COG0561	phosphatase activity
G3U99_04910	COG1280	lysine exporter protein (LysE YggA)
G3U99_04915	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G3U99_04920	COG0640	Transcriptional regulator
G3U99_04925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G3U99_04970	COG2095	MarC family integral membrane protein
G3U99_04980	COG0742	ribosomal rna small subunit methyltransferase
G3U99_04985	COG0552	protein localization to endoplasmic reticulum
G3U99_04990	COG2884	Cell division ATP-binding protein ftsE
G3U99_04995	COG2177	Part of the ABC transporter FtsEX involved in
G3U99_05000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G3U99_05005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G3U99_05015	COG1580	Controls the rotational direction of flagella during chemotaxis
G3U99_05020	COG3161	chorismate lyase activity
G3U99_05025	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G3U99_05030	COG2937	Belongs to the GPAT DAPAT family
G3U99_05035	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G3U99_05040	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G3U99_05050	COG0534	Mate efflux family protein
G3U99_05055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3U99_05075	COG4206	TonB-dependent receptor
G3U99_05085	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G3U99_05180	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G3U99_05190	COG0137	argininosuccinate synthase activity
G3U99_05195	COG0165	Argininosuccinate lyase
G3U99_05195	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G3U99_05205	COG0251	oxidation-reduction process
G3U99_05215	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G3U99_05215	COG0678	peroxiredoxin activity
G3U99_05225	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G3U99_05270	COG0338	D12 class N6 adenine-specific DNA methyltransferase
G3U99_05275	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G3U99_05280	COG0546	phosphoglycolate phosphatase activity
G3U99_05285	COG0180	Tryptophanyl-tRNA synthetase
G3U99_05290	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G3U99_05295	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G3U99_05300	COG2205	protein histidine kinase activity
G3U99_05305	COG0745	RESPONSE REGULATOR receiver
G3U99_05310	COG3678	ATP-independent chaperone mediated protein folding
G3U99_05320	COG0205	6-phosphofructokinase activity
G3U99_05325	COG1285	pathogenesis
G3U99_05335	COG1509	lysine 2,3-aminomutase activity
G3U99_05340	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G3U99_05345	COG1575	Belongs to the MenA family. Type 1 subfamily
G3U99_05350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3U99_05355	COG0534	Mate efflux family protein
G3U99_05360	COG0149	triose-phosphate isomerase activity
G3U99_05375	COG1072	(Pantothenic acid kinase))
G3U99_05400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G3U99_05410	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G3U99_05415	COG0250	Participates in transcription elongation, termination and antitermination
G3U99_05430	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G3U99_05440	COG0085	RNA polymerase activity
G3U99_05450	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
G3U99_05455	COG2816	NAD+ diphosphatase activity
G3U99_05475	COG4942	peptidase
G3U99_05480	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G3U99_05490	COG0840	transmembrane signaling receptor activity
G3U99_05495	COG0471	metal ion transport
G3U99_05495	COG0490	domain, Protein
G3U99_05500	COG0688	phosphatidylethanolamine metabolic process
G3U99_05505	COG1162	GTPase activity
G3U99_05510	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G3U99_05565	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G3U99_05570	COG0802	atpase or kinase
G3U99_05580	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G3U99_05595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G3U99_05600	COG0330	HflC and HflK could
G3U99_05605	COG0330	HflC and HflK could
G3U99_05610	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
G3U99_05625	COG0545	Peptidyl-prolyl cis-trans isomerase
G3U99_05630	COG2964	Protein conserved in bacteria
G3U99_05640	COG2923	Belongs to the DsrF TusC family
G3U99_05645	COG2168	tRNA wobble position uridine thiolation
G3U99_05655	COG0049	tRNA binding
G3U99_05660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G3U99_05665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G3U99_05670	COG2906	2 iron, 2 sulfur cluster binding
G3U99_05680	COG0360	Binds together with S18 to 16S ribosomal RNA
G3U99_05700	COG0305	Participates in initiation and elongation during chromosome replication
G3U99_05705	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G3U99_05710	COG0432	Pfam Uncharacterised protein family UPF0047
G3U99_05735	COG1136	(ABC) transporter
G3U99_05750	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
G3U99_05760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3U99_05765	COG0729	surface antigen
G3U99_05775	COG2105	PFAM AIG2 family protein
G3U99_05780	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G3U99_05790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G3U99_05795	COG0163	prenyltransferase activity
G3U99_05800	COG4143	(ABC) transporter
G3U99_05805	COG1178	ABC-type Fe3 transport system permease component
G3U99_05810	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
G3U99_05815	COG3028	Belongs to the UPF0307 family
G3U99_05820	COG0312	modulator of DNA gyrase
G3U99_05825	COG0527	aspartate kinase activity
G3U99_05830	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G3U99_05840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G3U99_05855	COG0629	single-stranded DNA binding
G3U99_05860	COG2199	diguanylate cyclase activity
G3U99_05860	COG2200	EAL domain
G3U99_05885	COG3267	Type II secretory pathway component ExeA
G3U99_05885	COG3409	Peptidoglycan-binding domain 1 protein
G3U99_05895	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G3U99_05900	COG1459	type II secretion system
G3U99_05945	COG1077	Cell shape determining protein MreB Mrl
G3U99_05950	COG1792	Involved in formation and maintenance of cell shape
G3U99_05955	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G3U99_05960	COG0424	maF-like protein
G3U99_05965	COG1530	ribonuclease E activity
G3U99_05970	COG3164	Protein of unknown function
G3U99_05975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3U99_05980	COG0312	modulator of DNA gyrase
G3U99_06035	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
G3U99_06045	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G3U99_06050	COG2066	Belongs to the glutaminase family
G3U99_06055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G3U99_06060	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G3U99_06175	COG0762	integral membrane protein
G3U99_06180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G3U99_06185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G3U99_06200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G3U99_06205	COG1678	Uncharacterized ACR, COG1678
G3U99_06210	COG0189	ligase activity
G3U99_06215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G3U99_06220	COG2356	endonuclease I
G3U99_06225	COG3091	SprT-like family
G3U99_06235	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G3U99_06245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G3U99_06255	COG0191	fructose-bisphosphate aldolase activity
G3U99_06260	COG0668	transmembrane transport
G3U99_06265	COG0442	prolyl-tRNA aminoacylation
G3U99_06275	COG0583	DNA-binding transcription factor activity
G3U99_06285	COG3706	GGDEF domain
G3U99_06295	COG0469	pyruvate kinase activity
G3U99_06300	COG1349	DNA-binding transcription factor activity
G3U99_06305	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G3U99_06310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3U99_06315	COG3722	fumarate hydratase activity
G3U99_06325	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3U99_06325	COG2213	PTS system mannitol-specific
G3U99_06330	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G3U99_06340	COG0142	geranyltranstransferase activity
G3U99_06345	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G3U99_06355	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G3U99_06360	COG2966	Psort location CytoplasmicMembrane, score
G3U99_06365	COG3610	response to peptide
G3U99_06375	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G3U99_06385	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G3U99_06395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3U99_06405	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G3U99_06420	COG0358	DNA primase activity
G3U99_06425	COG1610	YqeY-like protein
G3U99_06430	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G3U99_06435	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G3U99_06445	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G3U99_06450	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G3U99_06455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G3U99_06465	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G3U99_06470	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G3U99_06480	COG0585	pseudouridine synthase activity
G3U99_06485	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G3U99_06500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G3U99_06505	COG4536	flavin adenine dinucleotide binding
G3U99_06510	COG4137	Cytochrome C assembly protein
G3U99_06515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G3U99_06520	COG0228	four-way junction DNA binding
G3U99_06530	COG0336	Belongs to the RNA methyltransferase TrmD family
G3U99_06540	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G3U99_06545	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
G3U99_06550	COG0237	dephospho-CoA kinase activity
G3U99_06560	COG1459	type II secretion system
G3U99_06565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G3U99_06570	COG4969	Belongs to the N-Me-Phe pilin family
G3U99_06575	COG0157	Belongs to the NadC ModD family
G3U99_06580	COG3023	N-Acetylmuramoyl-L-alanine amidase
G3U99_06590	COG4974	Belongs to the 'phage' integrase family
G3U99_06595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G3U99_06600	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G3U99_06605	COG2186	Transcriptional regulator
G3U99_06610	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G3U99_06615	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3U99_06620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3U99_06635	COG0288	reversible hydration of carbon dioxide
G3U99_06640	COG0659	secondary active sulfate transmembrane transporter activity
G3U99_06645	COG1131	(ABC) transporter
G3U99_06650	COG0842	Transport permease protein
G3U99_06660	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G3U99_06665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G3U99_06680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G3U99_06690	COG1643	Atp-dependent helicase
G3U99_06695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3U99_06700	COG1752	Esterase of the alpha-beta hydrolase superfamily
G3U99_06705	COG1049	propionate catabolic process, 2-methylcitrate cycle
G3U99_06720	COG0004	ammonium transporteR
G3U99_06725	COG1840	ABC-type Fe3 transport system, periplasmic component
G3U99_06735	COG3842	ATPase activity
G3U99_06740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3U99_06755	COG2971	BadF BadG BcrA BcrD
G3U99_06765	COG4608	Belongs to the ABC transporter superfamily
G3U99_06770	COG0444	Belongs to the ABC transporter superfamily
G3U99_06785	COG0747	negative chemotaxis
G3U99_06790	COG2205	protein histidine kinase activity
G3U99_06790	COG0784	Response regulator, receiver
G3U99_06795	COG2813	Specifically methylates the guanine in position
G3U99_06800	COG0628	permease
G3U99_06825	COG0739	heme binding
G3U99_06830	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G3U99_06835	COG2239	Acts as a magnesium transporter
G3U99_06840	COG2027	D-alanyl-D-alanine carboxypeptidase
G3U99_06845	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
G3U99_06850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3U99_06855	COG1534	Rna-binding protein
G3U99_06860	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G3U99_06865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3U99_06870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G3U99_06875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3U99_06900	COG0513	Belongs to the DEAD box helicase family
G3U99_06920	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G3U99_06925	COG0826	peptidase U32
G3U99_06930	COG0826	peptidase U32
G3U99_06940	COG3154	lipid carrier protein
G3U99_06945	COG3153	acetyltransferase
G3U99_06950	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G3U99_06965	COG0779	Required for maturation of 30S ribosomal subunits
G3U99_06970	COG0195	Participates in both transcription termination and antitermination
G3U99_06995	COG0493	'glutamate synthase
G3U99_07000	COG0069	glutamate synthase activity
G3U99_07000	COG0070	glutamate synthase
G3U99_07000	COG0067	glutamate synthase
G3U99_07010	COG0070	glutamate synthase
G3U99_07010	COG0069	glutamate synthase activity
G3U99_07010	COG0067	glutamate synthase
G3U99_07015	COG1242	4 iron, 4 sulfur cluster binding
G3U99_07020	COG4251	negative regulation of phosphorylation
G3U99_07020	COG5001	Diguanylate cyclase
G3U99_07020	COG3706	GGDEF domain
G3U99_07020	COG2203	Gaf domain
G3U99_07025	COG2198	Histidine kinase
G3U99_07025	COG5002	protein histidine kinase activity
G3U99_07025	COG0784	Response regulator, receiver
G3U99_07035	COG1538	Outer membrane efflux protein
G3U99_07040	COG0494	nUDIX hydrolase
G3U99_07045	COG3151	Protein conserved in bacteria
G3U99_07055	COG3150	esterase
G3U99_07070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3U99_07075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3U99_07080	COG3105	Protein conserved in bacteria
G3U99_07085	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G3U99_07100	COG0723	plastoquinol--plastocyanin reductase activity
G3U99_07105	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G3U99_07110	COG2857	Cytochrome c1
G3U99_07115	COG0625	glutathione transferase activity
G3U99_07120	COG2969	positive regulation of protein catabolic process
G3U99_07130	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G3U99_07140	COG3107	peptidoglycan biosynthetic process
G3U99_07145	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G3U99_07160	COG3116	cell division
G3U99_07165	COG0768	penicillin binding
G3U99_07170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G3U99_07175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G3U99_07185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G3U99_07190	COG0772	Belongs to the SEDS family
G3U99_07205	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G3U99_07210	COG0849	cell division
G3U99_07215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G3U99_07220	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
G3U99_07225	COG0653	protein targeting
G3U99_07230	COG0494	nUDIX hydrolase
G3U99_07240	COG0505	Belongs to the CarA family
G3U99_07245	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G3U99_07250	COG0730	response to heat
G3U99_07255	COG0583	DNA-binding transcription factor activity
G3U99_07260	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
G3U99_07270	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G3U99_07285	COG1115	amino acid carrier protein
G3U99_07290	COG3022	response to hydroperoxide
G3U99_07300	COG0084	hydrolase, TatD family'
G3U99_07305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G3U99_07320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G3U99_07325	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G3U99_07330	COG0813	purine-nucleoside phosphorylase activity
G3U99_07340	COG0560	Phosphoserine phosphatase
G3U99_07350	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
G3U99_07355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G3U99_07360	COG0693	protein deglycase activity
G3U99_07365	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3U99_07380	COG1595	DNA-templated transcription, initiation
G3U99_07395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G3U99_07405	COG2813	Specifically methylates the guanine in position
G3U99_07410	COG0271	Belongs to the BolA IbaG family
G3U99_07415	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G3U99_07420	COG1805	sodium ion transport
G3U99_07435	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G3U99_07440	COG2871	sodium ion transport
G3U99_07445	COG1477	protein flavinylation
G3U99_07460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G3U99_07465	COG0514	ATP-dependent DNA helicase (RecQ)
G3U99_07470	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3U99_07485	COG0733	neurotransmitter:sodium symporter activity
G3U99_07495	COG0189	ligase activity
G3U99_07500	COG4067	protein conserved in archaea
G3U99_07500	COG0189	ligase activity
G3U99_07505	COG2195	Cleaves the N-terminal amino acid of tripeptides
G3U99_07510	COG2252	PERMEase
G3U99_07515	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
G3U99_07530	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G3U99_07535	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G3U99_07540	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G3U99_07545	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3U99_07545	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3U99_07565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G3U99_07570	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G3U99_07575	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G3U99_07590	COG0024	Methionine aminopeptidase
G3U99_07595	COG0052	Belongs to the universal ribosomal protein uS2 family
G3U99_07600	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G3U99_07605	COG0528	UMP kinase activity
G3U99_07610	COG0233	cytoplasmic translational termination
G3U99_07615	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G3U99_07620	COG0575	Belongs to the CDS family
G3U99_07630	COG0750	zinc metalloprotease
G3U99_07635	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3U99_07640	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
G3U99_07645	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3U99_07650	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G3U99_07665	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G3U99_07670	COG0587	DNA-directed DNA polymerase activity
G3U99_07675	COG0825	malonyl-CoA metabolic process
G3U99_07690	COG0347	Belongs to the P(II) protein family
G3U99_07695	COG3021	interspecies interaction between organisms
G3U99_07705	COG1388	LysM domain
G3U99_07705	COG0741	lytic transglycosylase activity
G3U99_07715	COG2226	methyltransferase
G3U99_07720	COG0328	RNA-DNA hybrid ribonuclease activity
G3U99_07735	COG1960	acyl-CoA dehydrogenase activity
G3U99_07740	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G3U99_07745	COG0121	glutamine amidotransferase
G3U99_07755	COG1720	tRNA m6t6A37 methyltransferase activity
G3U99_07770	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
G3U99_07780	COG1464	Belongs to the NlpA lipoprotein family
G3U99_07785	COG2011	ABC-type metal ion transport system permease component
G3U99_07790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G3U99_07795	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G3U99_07805	COG1609	Transcriptional regulator
G3U99_07810	COG1263	PTS System
G3U99_07810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G3U99_07815	COG0366	Alpha amylase catalytic
G3U99_07840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_07845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3U99_07855	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G3U99_07870	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G3U99_07880	COG2921	Belongs to the UPF0250 family
G3U99_07885	COG1686	Belongs to the peptidase S11 family
G3U99_07890	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G3U99_07895	COG0772	Belongs to the SEDS family
G3U99_07900	COG0768	penicillin binding
G3U99_07905	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G3U99_07910	COG0799	negative regulation of ribosome biogenesis
G3U99_07915	COG1466	dna polymerase III delta subunit
G3U99_07920	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
G3U99_07925	COG0495	leucyl-tRNA aminoacylation
G3U99_07930	COG2888	peptidyl-tyrosine sulfation
G3U99_07935	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G3U99_07940	COG4535	Mg2 and Co2 transporter CorC
G3U99_07945	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G3U99_07950	COG1702	phosphate starvation-inducible protein PhoH
G3U99_07960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3U99_07965	COG2190	(PTS) system
G3U99_07970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G3U99_07975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3U99_07980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G3U99_07985	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
G3U99_07990	COG3115	cell septum assembly
G3U99_08015	COG0330	HflC and HflK could
G3U99_08020	COG3118	belongs to the thioredoxin family
G3U99_08030	COG0300	oxidoreductase activity
G3U99_08035	COG1090	epimerase
G3U99_08060	COG0622	Phosphoesterase
G3U99_08080	COG3710	Transcriptional regulator
G3U99_08085	COG0326	Molecular chaperone. Has ATPase activity
G3U99_08095	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G3U99_08115	COG2608	mercury ion transmembrane transporter activity
G3U99_08115	COG2217	Heavy metal translocating P-type atpase
G3U99_08155	COG2194	sulfuric ester hydrolase activity
G3U99_08165	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
G3U99_08205	COG2747	anti-sigma28 factor FlgM
G3U99_08215	COG0835	chemotaxis
G3U99_08215	COG0784	Response regulator, receiver
G3U99_08220	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G3U99_08225	COG1815	bacterial-type flagellum-dependent cell motility
G3U99_08245	COG4787	bacterial-type flagellum-dependent cell motility
G3U99_08255	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G3U99_08260	COG1706	bacterial-type flagellum-dependent cell motility
G3U99_08265	COG1705	Flagellar rod assembly protein muramidase FlgJ
G3U99_08265	COG3951	Flagellar rod assembly protein muramidase FlgJ
G3U99_08275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G3U99_08280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G3U99_08395	COG0012	GTP binding
G3U99_08405	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G3U99_08430	COG2890	protein-(glutamine-N5) methyltransferase activity
G3U99_08440	COG2912	Transglutaminase-like superfamily
G3U99_08445	COG2877	3-deoxy-8-phosphooctulonate synthase activity
G3U99_08455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G3U99_08460	COG2233	PERMEase
G3U99_08480	COG1393	Belongs to the ArsC family
G3U99_08485	COG4783	chaperone-mediated protein folding
G3U99_08505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G3U99_08510	COG2716	regulation of RNA biosynthetic process
G3U99_08525	COG2056	Na+-H+ antiporter family
G3U99_08545	COG0346	lactoylglutathione lyase activity
G3U99_08550	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G3U99_08565	COG4658	electron transport chain
G3U99_08570	COG4656	Part of a membrane complex involved in electron transport
G3U99_08580	COG4657	Part of a membrane complex involved in electron transport
G3U99_08585	COG1388	LysM domain
G3U99_08585	COG0741	lytic transglycosylase activity
G3U99_08605	COG1815	bacterial-type flagellum-dependent cell motility
G3U99_08610	COG1558	bacterial-type flagellum-dependent cell motility
G3U99_08620	COG1749	Flagellar hook protein flgE
G3U99_08625	COG4787	bacterial-type flagellum-dependent cell motility
G3U99_08630	COG4786	Flagellar basal body rod
G3U99_08635	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G3U99_08640	COG1706	bacterial-type flagellum-dependent cell motility
G3U99_08670	COG1360	Flagellar Motor Protein
G3U99_08675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G3U99_08680	COG1191	sigma factor activity
G3U99_08685	COG1580	Controls the rotational direction of flagella during chemotaxis
G3U99_08700	COG1516	flagellar protein fliS
G3U99_08705	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G3U99_08710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G3U99_08725	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G3U99_08735	COG1987	bacterial-type flagellum assembly
G3U99_08755	COG2885	chlorophyll binding
G3U99_08800	COG0739	heme binding
G3U99_08820	COG0556	nucleotide-excision repair
G3U99_08830	COG2198	Histidine kinase
G3U99_08835	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G3U99_08840	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G3U99_08845	COG0521	Mo-molybdopterin cofactor biosynthetic process
G3U99_08855	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G3U99_08860	COG0314	molybdopterin synthase activity
G3U99_08865	COG3706	GGDEF domain
G3U99_08875	COG0617	tRNA 3'-terminal CCA addition
G3U99_08875	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G3U99_08875	COG0517	IMP dehydrogenase activity
G3U99_08905	COG0745	RESPONSE REGULATOR receiver
G3U99_08915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3U99_08915	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3U99_08920	COG0489	protein tyrosine kinase activity
G3U99_08925	COG0572	uridine kinase
G3U99_08930	COG2982	Protein involved in outer membrane biogenesis
G3U99_08980	COG0110	maltose O-acetyltransferase activity
G3U99_08985	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
G3U99_08995	COG0302	gtp cyclohydrolase
G3U99_09000	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G3U99_09005	COG0302	gtp cyclohydrolase
G3U99_09005	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G3U99_09010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G3U99_09030	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G3U99_09035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G3U99_09045	COG1881	PFAM PEBP family protein
G3U99_09055	COG0123	including yeast histone deacetylase and acetoin utilization protein
G3U99_09100	COG0840	transmembrane signaling receptor activity
G3U99_09115	COG3083	sulfuric ester hydrolase activity
G3U99_09120	COG3082	Protein of unknown function (DUF1414)
G3U99_09145	COG1757	Na H antiporter
G3U99_09150	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G3U99_09155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3U99_09160	COG2095	MarC family integral membrane protein
G3U99_09165	COG1454	alcohol dehydrogenase
G3U99_09165	COG1012	belongs to the aldehyde dehydrogenase family
G3U99_09170	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G3U99_09175	COG2894	cell division
G3U99_09180	COG0850	regulation of cytokinetic process
G3U99_09185	COG3100	YcgL domain-containing protein
G3U99_09190	COG2951	lytic endotransglycosylase activity
G3U99_09195	COG0583	DNA-binding transcription factor activity
G3U99_09200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G3U99_09215	COG2983	Belongs to the UPF0260 family
G3U99_09220	COG0668	transmembrane transport
G3U99_09240	COG1785	Belongs to the alkaline phosphatase family
G3U99_09255	COG2226	methyltransferase
G3U99_09260	COG0840	transmembrane signaling receptor activity
G3U99_09275	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3U99_09285	COG3139	Protein of unknown function (DUF1315)
G3U99_09290	COG3012	SEC-C Motif Domain Protein
G3U99_09295	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G3U99_09305	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G3U99_09310	COG0215	cysteine-tRNA ligase activity
G3U99_09315	COG1435	thymidine kinase activity
G3U99_09320	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G3U99_09325	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G3U99_09350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G3U99_09355	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G3U99_09380	COG3070	regulator of competence-specific genes
G3U99_09395	COG0745	RESPONSE REGULATOR receiver
G3U99_09400	COG1434	Gram-negative-bacterium-type cell wall biogenesis
G3U99_09405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3U99_09415	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
G3U99_09420	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
G3U99_09450	COG4067	protein conserved in archaea
G3U99_09450	COG0189	ligase activity
G3U99_09455	COG0500	methyltransferase
G3U99_09465	COG1801	Protein of unknown function DUF72
G3U99_09475	COG1187	pseudouridine synthase activity
G3U99_09485	COG1278	Cold shock
G3U99_09495	COG0542	response to heat
G3U99_09520	COG2116	formate transmembrane transporter activity
G3U99_09525	COG0390	transport system, permease component
G3U99_09530	COG4459	periplasmic nitrate reductase
G3U99_09535	COG3005	denitrification pathway
G3U99_09540	COG0243	molybdopterin cofactor binding
G3U99_09550	COG4221	oxidoreductase activity
G3U99_09570	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G3U99_09575	COG0840	transmembrane signaling receptor activity
G3U99_09580	COG0632	four-way junction helicase activity
G3U99_09585	COG2255	four-way junction helicase activity
G3U99_09590	COG1271	oxidase subunit
G3U99_09595	COG1294	oxidase, subunit
G3U99_09600	COG4890	Cyd operon protein YbgT
G3U99_09610	COG0824	Thioesterase
G3U99_09615	COG0811	peptide transport
G3U99_09635	COG2885	chlorophyll binding
G3U99_09640	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
G3U99_09645	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G3U99_09650	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G3U99_09660	COG5640	endopeptidase activity
G3U99_09675	COG5002	protein histidine kinase activity
G3U99_09675	COG0784	Response regulator, receiver
G3U99_09690	COG0556	nucleotide-excision repair
G3U99_09705	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G3U99_09720	COG1940	carbohydrate kinase activity
G3U99_09735	COG5002	protein histidine kinase activity
G3U99_09735	COG3850	Histidine kinase
G3U99_09740	COG0745	RESPONSE REGULATOR receiver
G3U99_09745	COG0463	Glycosyl transferase, family 2
G3U99_09750	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G3U99_09765	COG1960	acyl-CoA dehydrogenase activity
G3U99_09770	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G3U99_09775	COG0708	Exodeoxyribonuclease III
G3U99_09780	COG0840	transmembrane signaling receptor activity
G3U99_09785	COG2850	peptidyl-arginine hydroxylation
G3U99_09800	COG0730	response to heat
G3U99_09805	COG1199	ATP-dependent helicase activity
G3U99_09815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G3U99_09825	COG0156	8-amino-7-oxononanoate synthase activity
G3U99_09830	COG2226	methyltransferase
G3U99_09830	COG1073	alpha beta
G3U99_09835	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G3U99_09850	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_09865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3U99_09875	COG2268	Band 7 protein
G3U99_09885	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G3U99_09895	COG0482	sulfurtransferase activity
G3U99_09905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3U99_09915	COG1757	Na H antiporter
G3U99_09925	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G3U99_09935	COG0131	Imidazoleglycerol-phosphate dehydratase
G3U99_09935	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G3U99_09940	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G3U99_09945	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G3U99_09955	COG0140	phosphoribosyl-ATP diphosphatase activity
G3U99_09955	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G3U99_09960	COG0217	transcriptional regulatory protein
G3U99_09970	COG1227	inorganic diphosphatase activity
G3U99_09985	COG4172	Belongs to the ABC transporter superfamily
G3U99_09995	COG4171	peptide transport system, permease
G3U99_10010	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
G3U99_10015	COG1842	Phage shock protein A
G3U99_10025	COG1983	PspC domain protein
G3U99_10045	COG2818	Glycosylase
G3U99_10050	COG5380	lipid catabolic process
G3U99_10055	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G3U99_10060	COG0626	cystathionine gamma-synthase activity
G3U99_10070	COG0733	neurotransmitter:sodium symporter activity
G3U99_10075	COG0564	pseudouridine synthase activity
G3U99_10080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G3U99_10085	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G3U99_10090	COG4136	ATPase activity
G3U99_10095	COG4135	transport system, permease component
G3U99_10100	COG4134	Bacterial extracellular solute-binding protein
G3U99_10110	COG3313	Fe-S protein
G3U99_10125	COG2350	Protein conserved in bacteria
G3U99_10170	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G3U99_10185	COG0417	DNA replication proofreading
G3U99_10200	COG2197	response regulator
G3U99_10205	COG0322	excinuclease ABC activity
G3U99_10235	COG1902	pentaerythritol trinitrate reductase activity
G3U99_10245	COG2133	pyrroloquinoline quinone binding
G3U99_10270	COG3706	GGDEF domain
G3U99_10280	COG0072	phenylalanine-tRNA ligase activity
G3U99_10280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3U99_10330	COG1741	Belongs to the pirin family
G3U99_10335	COG1335	isochorismatase
G3U99_10345	COG1263	PTS System
G3U99_10345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G3U99_10360	COG1621	beta-fructofuranosidase activity
G3U99_10380	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G3U99_10385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3U99_10405	COG0583	DNA-binding transcription factor activity
G3U99_10415	COG0277	FAD linked oxidase domain protein
G3U99_10425	COG4211	Belongs to the binding-protein-dependent transport system permease family
G3U99_10440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3U99_10445	COG3962	Belongs to the TPP enzyme family
G3U99_10485	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G3U99_10490	COG0183	Belongs to the thiolase family
G3U99_10505	COG0583	DNA-binding transcription factor activity
G3U99_10510	COG0477	Major facilitator Superfamily
G3U99_10510	COG2814	Major facilitator Superfamily
G3U99_10520	COG3962	Belongs to the TPP enzyme family
G3U99_10525	COG0673	inositol 2-dehydrogenase activity
G3U99_10530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3U99_10555	COG3718	enzyme involved in inositol metabolism
G3U99_10560	COG0673	inositol 2-dehydrogenase activity
G3U99_10570	COG1216	Glycosyl transferase, family 2
G3U99_10585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G3U99_10595	COG3437	response regulator, receiver
G3U99_10600	COG0488	(ABC) transporter
G3U99_10605	COG2205	protein histidine kinase activity
G3U99_10605	COG0784	Response regulator, receiver
G3U99_10615	COG1858	cytochrome C peroxidase
G3U99_10635	COG0745	RESPONSE REGULATOR receiver
G3U99_10640	COG0642	Histidine kinase
G3U99_10650	COG1609	Transcriptional regulator
G3U99_10655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3U99_10670	COG1609	Transcriptional regulator
G3U99_10680	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G3U99_10720	COG0583	DNA-binding transcription factor activity
G3U99_10730	COG1012	belongs to the aldehyde dehydrogenase family
G3U99_10740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G3U99_10765	COG0583	DNA-binding transcription factor activity
G3U99_10770	COG0352	thiamine-phosphate diphosphorylase activity
G3U99_10775	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
G3U99_10780	COG1280	lysine exporter protein (LysE YggA)
G3U99_10785	COG1115	amino acid carrier protein
G3U99_10800	COG1987	bacterial-type flagellum assembly
G3U99_10810	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G3U99_10815	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G3U99_10820	COG4786	Flagellar basal body rod
G3U99_10825	COG4786	Flagellar basal body rod
G3U99_10835	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G3U99_10840	COG1706	bacterial-type flagellum-dependent cell motility
G3U99_10855	COG1677	Flagellar hook-basal body complex protein FliE
G3U99_10860	COG1766	The M ring may be actively involved in energy transduction
G3U99_10890	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
G3U99_10915	COG1191	sigma factor activity
G3U99_11030	COG3300	MHYT domain
G3U99_11030	COG5001	Diguanylate cyclase
G3U99_11090	COG0778	Nitroreductase
G3U99_11095	COG4580	involved in the transport of maltose and maltodextrins
G3U99_11115	COG0242	peptide deformylase activity
G3U99_11165	COG0307	riboflavin synthase, alpha
G3U99_11200	COG4221	oxidoreductase activity
G3U99_11235	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G3U99_11240	COG0583	DNA-binding transcription factor activity
G3U99_11270	COG0463	Glycosyl transferase, family 2
G3U99_11290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_11295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3U99_11320	COG2205	protein histidine kinase activity
G3U99_11335	COG1061	Type III restriction enzyme res subunit
G3U99_11345	COG2814	Major facilitator Superfamily
G3U99_11355	COG0702	epimerase
G3U99_11360	COG0534	Mate efflux family protein
G3U99_11365	COG1136	(ABC) transporter
G3U99_11410	COG0019	diaminopimelate decarboxylase activity
G3U99_11435	COG0633	Ferredoxin
G3U99_11440	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G3U99_11445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G3U99_11450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3U99_11460	COG0840	transmembrane signaling receptor activity
G3U99_11465	COG1328	CTP reductase activity
G3U99_11470	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G3U99_11515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3U99_11520	COG0745	RESPONSE REGULATOR receiver
G3U99_11525	COG2205	protein histidine kinase activity
G3U99_11540	COG0811	peptide transport
G3U99_11545	COG0811	peptide transport
G3U99_11550	COG0848	biopolymer transport protein
G3U99_11570	COG3290	protein histidine kinase activity
G3U99_11575	COG4565	transcriptional regulatory protein
G3U99_11605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3U99_11615	COG2116	formate transmembrane transporter activity
G3U99_11635	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G3U99_11640	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
G3U99_11655	COG0583	DNA-binding transcription factor activity
G3U99_11665	COG0745	RESPONSE REGULATOR receiver
G3U99_11675	COG3713	MltA-interacting MipA family protein
G3U99_11685	COG2186	Transcriptional regulator
G3U99_11695	COG1288	antiporter activity
G3U99_11705	COG2814	Major facilitator Superfamily
G3U99_11715	COG3835	regulator
G3U99_11720	COG1929	Belongs to the glycerate kinase type-1 family
G3U99_11725	COG2977	Belongs to the P-Pant transferase superfamily
G3U99_11730	COG1120	ATPase activity
G3U99_11735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G3U99_11745	COG4615	Cyclic peptide transporter
G3U99_11765	COG4774	siderophore transport
G3U99_11800	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G3U99_11810	COG0297	glycogen (starch) synthase activity
G3U99_11845	COG0438	transferase activity, transferring glycosyl groups
G3U99_11855	COG2204	response regulator
G3U99_11900	COG0534	Mate efflux family protein
G3U99_11905	COG0307	riboflavin synthase, alpha
G3U99_11915	COG3001	Fructosamine kinase
G3U99_11925	COG0791	NLP P60 protein
G3U99_11930	COG0840	transmembrane signaling receptor activity
G3U99_11945	COG1940	carbohydrate kinase activity
G3U99_11960	COG0303	'Molybdopterin
G3U99_11965	COG0746	molybdenum cofactor guanylyltransferase activity
G3U99_11970	COG3842	ATPase activity
G3U99_11990	COG3852	Histidine kinase
G3U99_12005	COG1595	DNA-templated transcription, initiation
G3U99_12015	COG0488	(ABC) transporter
G3U99_12030	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_12040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_12045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3U99_12050	COG3710	Transcriptional regulator
G3U99_12055	COG0069	glutamate synthase activity
G3U99_12075	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
G3U99_12080	COG0583	DNA-binding transcription factor activity
G3U99_12090	COG0583	DNA-binding transcription factor activity
G3U99_12115	COG3038	cytochrome b561
G3U99_12125	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G3U99_12155	COG3383	formate dehydrogenase (NAD+) activity
G3U99_12155	COG0243	molybdopterin cofactor binding
G3U99_12160	COG0437	4 iron, 4 sulfur cluster binding
G3U99_12175	COG0004	ammonium transporteR
G3U99_12180	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G3U99_12185	COG2199	diguanylate cyclase activity
G3U99_12190	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G3U99_12195	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G3U99_12200	COG1177	transmembrane transport
G3U99_12210	COG3842	ATPase activity
G3U99_12235	COG0589	response to stress
G3U99_12240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3U99_12255	COG2217	Heavy metal translocating P-type atpase
G3U99_12265	COG2010	Cytochrome c
G3U99_12280	COG3278	Belongs to the heme-copper respiratory oxidase family
G3U99_12315	COG2197	response regulator
G3U99_12410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3U99_12425	COG3424	synthase
G3U99_12560	COG0840	transmembrane signaling receptor activity
G3U99_12745	COG0789	Transcriptional regulator
G3U99_12800	COG1067	ATP-dependent peptidase activity
G3U99_12805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G3U99_12820	COG0488	(ABC) transporter
G3U99_12830	COG0116	Belongs to the methyltransferase superfamily
G3U99_12830	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G3U99_12840	COG0167	dihydroorotate dehydrogenase activity
G3U99_12855	COG0308	aminopeptidase N
G3U99_12870	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
G3U99_12875	COG1956	GAF domain-containing protein
G3U99_12880	COG1132	(ABC) transporter
G3U99_12885	COG2995	paraquat-inducible protein a
G3U99_12890	COG3008	intermembrane lipid transfer
G3U99_12920	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G3U99_12935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3U99_12940	COG4597	amino acid ABC transporter
G3U99_12945	COG0765	amino acid transport
G3U99_12950	COG1126	abc transporter atp-binding protein
G3U99_12955	COG0670	Belongs to the BI1 family
G3U99_12960	COG2920	part of a sulfur-relay system
G3U99_12965	COG1254	Belongs to the acylphosphatase family
G3U99_12970	COG0840	transmembrane signaling receptor activity
G3U99_12975	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G3U99_13005	COG0602	queuosine metabolic process
G3U99_13010	COG0561	phosphatase activity
G3U99_13030	COG2828	Protein conserved in bacteria
G3U99_13040	COG0372	Belongs to the citrate synthase family
G3U99_13045	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G3U99_13060	COG3501	Rhs element vgr protein
G3U99_13160	COG0515	serine threonine protein kinase
G3U99_13165	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G3U99_13190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_13205	COG4943	cyclic-guanylate-specific phosphodiesterase activity
G3U99_13225	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3U99_13225	COG0596	Alpha beta hydrolase
G3U99_13230	COG3063	Type IV pilus biogenesis stability protein PilW
G3U99_13245	COG1451	nucleotide metabolic process
G3U99_13255	COG0784	Response regulator, receiver
G3U99_13255	COG5002	protein histidine kinase activity
G3U99_13265	COG1119	ATPase activity
G3U99_13275	COG2814	Major facilitator Superfamily
G3U99_13285	COG2203	Gaf domain
G3U99_13285	COG2199	diguanylate cyclase activity
G3U99_13305	COG4139	cobalamin transport
G3U99_13320	COG0406	alpha-ribazole phosphatase activity
G3U99_13330	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G3U99_13340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3U99_13345	COG0702	epimerase
G3U99_13355	COG2925	Exonuclease
G3U99_13360	COG1380	Effector of murein hydrolase LrgA
G3U99_13365	COG1346	cytolysis
G3U99_13380	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G3U99_13460	COG0500	methyltransferase
G3U99_13480	COG4326	sporulation control protein
G3U99_13485	COG2188	Transcriptional regulator
G3U99_13490	COG1228	amidohydrolase
G3U99_13495	COG0010	Belongs to the arginase family
G3U99_13505	COG2986	histidine ammonia-lyase
G3U99_13520	COG0247	lactate metabolic process
G3U99_13520	COG0277	FAD linked oxidase domain protein
G3U99_13535	COG2885	chlorophyll binding
G3U99_13550	COG0625	glutathione transferase activity
G3U99_13560	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G3U99_13570	COG2195	Cleaves the N-terminal amino acid of tripeptides
G3U99_13585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3U99_13590	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G3U99_13600	COG0456	acetyltransferase
G3U99_13625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3U99_13630	COG0454	-acetyltransferase
G3U99_13685	COG3122	Protein conserved in bacteria
G3U99_13700	COG3040	lipid binding
G3U99_13715	COG0456	acetyltransferase
G3U99_13730	COG2824	Alkylphosphonate utilization operon protein PhnA
G3U99_13740	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_13750	COG0730	response to heat
G3U99_13775	COG4628	conserved protein (DUF2132)
G3U99_13830	COG3755	Protein conserved in bacteria
G3U99_14005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3U99_14005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3U99_14010	COG0346	lactoylglutathione lyase activity
G3U99_14025	COG0346	lactoylglutathione lyase activity
G3U99_14030	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G3U99_14140	COG2962	Rard protein
G3U99_14145	COG0531	amino acid
G3U99_14155	COG0783	Belongs to the Dps family
G3U99_14160	COG4667	esterase of the alpha-beta hydrolase superfamily
G3U99_14195	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G3U99_14210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3U99_14215	COG3108	Peptidase M15
G3U99_14220	COG2989	Protein conserved in bacteria
G3U99_14245	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G3U99_14250	COG3706	GGDEF domain
G3U99_14270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3U99_14280	COG3768	UPF0283 membrane protein
G3U99_14285	COG3106	COG3106 Predicted ATPase
G3U99_14305	COG0784	Response regulator, receiver
G3U99_14305	COG2205	protein histidine kinase activity
G3U99_14315	COG0494	nUDIX hydrolase
G3U99_14320	COG0814	amino acid
G3U99_14325	COG1760	l-serine dehydratase
G3U99_14335	COG0814	amino acid
G3U99_14350	COG0017	Asparaginyl-tRNA synthetase
G3U99_14365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3U99_14375	COG3437	response regulator, receiver
G3U99_14375	COG2770	Histidine kinase
G3U99_14380	COG1448	Aminotransferase
G3U99_14395	COG1643	Atp-dependent helicase
G3U99_14400	COG0281	malic enzyme
G3U99_14410	COG2949	membrane
G3U99_14420	COG0612	Peptidase, M16
G3U99_14450	COG0492	ferredoxin-NADP+ reductase activity
G3U99_14455	COG4988	ABC transporter
G3U99_14460	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G3U99_14465	COG2814	Major facilitator Superfamily
G3U99_14475	COG0384	phenazine biosynthesis protein PhzF
G3U99_14480	COG1187	pseudouridine synthase activity
G3U99_14495	COG0009	L-threonylcarbamoyladenylate synthase
G3U99_14500	COG0613	PHP domain protein
G3U99_14510	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G3U99_14515	COG0512	Glutamine amidotransferase of anthranilate synthase
G3U99_14520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G3U99_14525	COG0134	indole-3-glycerol-phosphate synthase activity
G3U99_14525	COG0135	phosphoribosylanthranilate isomerase activity
G3U99_14535	COG0159	tryptophan synthase activity
G3U99_14540	COG1301	dicarboxylic acid transport
G3U99_14550	COG1643	Atp-dependent helicase
G3U99_14605	COG0443	Heat shock 70 kDa protein
G3U99_14610	COG0443	Heat shock 70 kDa protein
G3U99_14620	COG1858	cytochrome C peroxidase
G3U99_14665	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3U99_14670	COG0840	transmembrane signaling receptor activity
G3U99_14690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G3U99_14695	COG0673	inositol 2-dehydrogenase activity
G3U99_14705	COG0583	DNA-binding transcription factor activity
G3U99_14715	COG1846	Transcriptional regulator
G3U99_14720	COG1764	response to oxidative stress
G3U99_14725	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G3U99_14755	COG1032	radical SAM domain protein
G3U99_14765	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G3U99_14775	COG4191	Histidine kinase
G3U99_14775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3U99_14790	COG3070	regulator of competence-specific genes
G3U99_14800	COG2431	L-lysine efflux transmembrane transporter activity
G3U99_14810	COG0076	glutamate decarboxylase activity
G3U99_14815	COG1737	Transcriptional regulator
G3U99_14820	COG1454	alcohol dehydrogenase
G3U99_14820	COG1012	belongs to the aldehyde dehydrogenase family
G3U99_14825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G3U99_14860	COG1882	Formate acetyltransferase
G3U99_14875	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G3U99_14890	COG3713	MltA-interacting MipA family protein
G3U99_14895	COG2766	serine protein kinase
G3U99_14900	COG2718	Belongs to the UPF0229 family
G3U99_14905	COG2719	SpoVR family
G3U99_14910	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G3U99_14915	COG2835	tetraacyldisaccharide 4'-kinase activity
G3U99_14925	COG1132	(ABC) transporter
G3U99_14930	COG2333	competence protein COMEC
G3U99_14930	COG0658	competence protein
G3U99_14940	COG4591	ABC-type transport system involved in lipoprotein release permease component
G3U99_14945	COG1136	(ABC) transporter
G3U99_14950	COG4591	ABC-type transport system involved in lipoprotein release permease component
G3U99_14960	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G3U99_14980	COG1252	NADH dehydrogenase
G3U99_15010	COG0537	adenosine 5'-monophosphoramidase activity
G3U99_15025	COG2186	Transcriptional regulator
G3U99_15030	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G3U99_15040	COG1674	ftsk spoiiie
G3U99_15050	COG0686	Belongs to the AlaDH PNT family
G3U99_15055	COG3092	negative regulation of chromosome organization
G3U99_15060	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G3U99_15065	COG0280	phosphate acetyltransferase
G3U99_15065	COG0857	belongs to the CobB CobQ family
G3U99_15070	COG3706	GGDEF domain
G3U99_15075	COG0435	Glutathione S-transferase
G3U99_15085	COG0444	Belongs to the ABC transporter superfamily
G3U99_15090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3U99_15095	COG0601	transmembrane transport
G3U99_15110	COG2067	long-chain fatty acid transport protein
G3U99_15115	COG3706	GGDEF domain
G3U99_15140	COG1404	Belongs to the peptidase S8 family
G3U99_15145	COG0840	transmembrane signaling receptor activity
G3U99_15160	COG0330	HflC and HflK could
G3U99_15180	COG0577	efflux transmembrane transporter activity
G3U99_15180	COG1136	(ABC) transporter
G3U99_15185	COG1136	(ABC) transporter
G3U99_15185	COG0577	efflux transmembrane transporter activity
G3U99_15190	COG0577	efflux transmembrane transporter activity
G3U99_15200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_15210	COG3227	Zinc metalloprotease (Elastase)
G3U99_15220	COG1770	oligopeptidase
G3U99_15225	COG3397	chitin binding
G3U99_15245	COG3876	Protein conserved in bacteria
G3U99_15250	COG1472	Belongs to the glycosyl hydrolase 3 family
G3U99_15270	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G3U99_15275	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3U99_15280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3U99_15295	COG2855	membrane
G3U99_15315	COG0730	response to heat
G3U99_15320	COG0280	phosphate acetyltransferase
G3U99_15325	COG1414	Transcriptional regulator
G3U99_15360	COG3706	GGDEF domain
G3U99_15375	COG3126	Type III secretion system lipoprotein chaperone (YscW)
G3U99_15380	COG1946	Acyl-CoA thioesterase
G3U99_15395	COG1522	sequence-specific DNA binding
G3U99_15420	COG0477	Major facilitator Superfamily
G3U99_15425	COG2855	membrane
G3U99_15430	COG0318	PFAM AMP-dependent synthetase and ligase
G3U99_15445	COG0596	Alpha beta hydrolase
G3U99_15450	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
G3U99_15455	COG1169	isochorismate synthase
G3U99_15460	COG0436	Aminotransferase
G3U99_15465	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
G3U99_15475	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G3U99_15480	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3U99_15495	COG0513	Belongs to the DEAD box helicase family
G3U99_15500	COG0616	signal peptide processing
G3U99_15505	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_15520	COG0587	DNA-directed DNA polymerase activity
G3U99_15525	COG0784	Response regulator, receiver
G3U99_15525	COG0835	chemotaxis
G3U99_15530	COG1940	carbohydrate kinase activity
G3U99_15535	COG0469	pyruvate kinase activity
G3U99_15540	COG4667	esterase of the alpha-beta hydrolase superfamily
G3U99_15555	COG0733	neurotransmitter:sodium symporter activity
G3U99_15570	COG1263	PTS System
G3U99_15570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G3U99_15575	COG0084	hydrolase, TatD family'
G3U99_15580	COG0470	DNA polymerase III
G3U99_15585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G3U99_15590	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G3U99_15595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G3U99_15620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3U99_15635	COG1399	metal-binding, possibly nucleic acid-binding protein
G3U99_15640	COG0424	maF-like protein
G3U99_15645	COG0564	pseudouridine synthase activity
G3U99_15650	COG1530	ribonuclease E activity
G3U99_15655	COG0659	secondary active sulfate transmembrane transporter activity
G3U99_15660	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
G3U99_15665	COG0318	PFAM AMP-dependent synthetase and ligase
G3U99_15685	COG1214	PFAM Peptidase M22, glycoprotease
G3U99_15690	COG1199	ATP-dependent helicase activity
G3U99_15700	COG0788	formyltetrahydrofolate deformylase activity
G3U99_15705	COG1902	pentaerythritol trinitrate reductase activity
G3U99_15705	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3U99_15710	COG0616	signal peptide processing
G3U99_15715	COG0252	asparaginase activity
G3U99_15725	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G3U99_15730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G3U99_15745	COG2165	general secretion pathway protein
G3U99_15750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G3U99_15755	COG3706	GGDEF domain
G3U99_15765	COG4120	Belongs to the binding-protein-dependent transport system permease family
G3U99_15800	COG0284	orotidine-5'-phosphate decarboxylase activity
G3U99_15805	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
G3U99_15810	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
G3U99_15820	COG0539	negative regulation of cytoplasmic translation
G3U99_15830	COG1555	photosystem II stabilization
G3U99_15835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3U99_15840	COG0776	regulation of translation
G3U99_15845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G3U99_15870	COG2204	response regulator
G3U99_15880	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3U99_15885	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G3U99_15890	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3U99_15895	COG3842	ATPase activity
G3U99_15905	COG1175	transmembrane transport
G3U99_15910	COG1653	transport
G3U99_15920	COG0745	RESPONSE REGULATOR receiver
G3U99_15945	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G3U99_15960	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G3U99_15965	COG2832	Protein of unknown function (DUF454)
G3U99_15970	COG0745	RESPONSE REGULATOR receiver
G3U99_15975	COG0583	DNA-binding transcription factor activity
G3U99_15980	COG0778	Nitroreductase
G3U99_15990	COG0183	Belongs to the thiolase family
G3U99_16005	COG2067	long-chain fatty acid transport protein
G3U99_16010	COG2067	long-chain fatty acid transport protein
G3U99_16015	COG2853	Lipoprotein
G3U99_16025	COG4235	cytochrome complex assembly
G3U99_16025	COG3088	subunit of a heme lyase
G3U99_16030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G3U99_16035	COG1138	Cytochrome C-type biogenesis protein
G3U99_16045	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G3U99_16050	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G3U99_16055	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G3U99_16060	COG4133	protoheme IX ABC transporter activity
G3U99_16070	COG0835	chemotaxis
G3U99_16080	COG1192	Involved in chromosome partitioning
G3U99_16085	COG2201	protein-glutamate methylesterase activity
G3U99_16090	COG2198	Histidine kinase
G3U99_16090	COG0784	Response regulator, receiver
G3U99_16090	COG0643	Histidine kinase
G3U99_16095	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
G3U99_16125	COG2062	phosphohistidine phosphatase, SixA
G3U99_16130	COG1025	Belongs to the peptidase M16 family
G3U99_16135	COG3102	Protein conserved in bacteria
G3U99_16140	COG0018	arginyl-trna synthetase
G3U99_16155	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
G3U99_16160	COG1918	ferrous iron import across plasma membrane
G3U99_16165	COG4977	sequence-specific DNA binding
G3U99_16170	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
G3U99_16175	COG1121	(ABC) transporter
G3U99_16180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G3U99_16185	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G3U99_16190	COG1286	toxin biosynthetic process
G3U99_16195	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
G3U99_16200	COG0285	dihydrofolate synthase activity
G3U99_16205	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G3U99_16210	COG0101	tRNA pseudouridine synthase activity
G3U99_16220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G3U99_16225	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3U99_16230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3U99_16265	COG2205	protein histidine kinase activity
G3U99_16270	COG0745	RESPONSE REGULATOR receiver
G3U99_16290	COG0628	permease
G3U99_16330	COG2860	membrane
G3U99_16340	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G3U99_16345	COG2890	protein-(glutamine-N5) methyltransferase activity
G3U99_16360	COG1684	flagellar biosynthetic protein fliR
G3U99_16365	COG1987	bacterial-type flagellum assembly
G3U99_16420	COG2146	nitrite reductase [NAD(P)H] activity
G3U99_16425	COG2146	nitrite reductase [NAD(P)H] activity
G3U99_16425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3U99_16430	COG1116	anion transmembrane transporter activity
G3U99_16435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3U99_16440	COG1116	anion transmembrane transporter activity
G3U99_16440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3U99_16450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G3U99_16455	COG1648	precorrin-2 dehydrogenase activity
G3U99_16455	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G3U99_16460	COG0243	molybdopterin cofactor binding
G3U99_16500	COG2315	Protein conserved in bacteria
G3U99_16510	COG2199	diguanylate cyclase activity
G3U99_16510	COG2203	Gaf domain
G3U99_16535	COG3706	GGDEF domain
G3U99_16555	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
G3U99_16560	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_16570	COG1024	Enoyl-CoA hydratase
G3U99_16575	COG1024	Enoyl-CoA hydratase
G3U99_16590	COG0183	Belongs to the thiolase family
G3U99_16600	COG1960	acyl-CoA dehydrogenase activity
G3U99_16605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3U99_16640	COG2259	Doxx family
G3U99_16645	COG1741	Belongs to the pirin family
G3U99_16660	COG1115	amino acid carrier protein
G3U99_16665	COG0583	DNA-binding transcription factor activity
G3U99_16670	COG2910	NAD(P)H-binding
G3U99_16690	COG1716	ATPase activity
G3U99_16690	COG5001	Diguanylate cyclase
G3U99_16715	COG1858	cytochrome C peroxidase
G3U99_16745	COG0583	DNA-binding transcription factor activity
G3U99_16750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G3U99_16755	COG5001	Diguanylate cyclase
G3U99_16755	COG3300	MHYT domain
G3U99_16765	COG0789	Transcriptional regulator
G3U99_16775	COG2176	DNA-directed DNA polymerase activity
G3U99_16780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G3U99_16785	COG1846	Transcriptional regulator
G3U99_16790	COG3706	GGDEF domain
G3U99_16815	COG2814	Major facilitator Superfamily
G3U99_16820	COG2425	protein containing a von Willebrand factor type A (vWA) domain
G3U99_16825	COG0714	Associated with various cellular activities
G3U99_16830	COG0494	nUDIX hydrolase
G3U99_16840	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_16850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3U99_16855	COG0835	chemotaxis
G3U99_16855	COG0784	Response regulator, receiver
G3U99_16860	COG3706	GGDEF domain
G3U99_16885	COG1760	l-serine dehydratase
G3U99_16890	COG0583	DNA-binding transcription factor activity
G3U99_16900	COG2866	Carboxypeptidase
G3U99_16905	COG3104	oligopeptide transport
G3U99_16930	COG3842	ATPase activity
G3U99_16940	COG1840	ABC-type Fe3 transport system, periplasmic component
G3U99_16945	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G3U99_16980	COG1011	Hydrolase
G3U99_16990	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
G3U99_16995	COG1454	alcohol dehydrogenase
G3U99_17040	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3U99_17045	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3U99_17085	COG3186	Phenylalanine-4-hydroxylase
G3U99_17090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3U99_17095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3U99_17115	COG0784	Response regulator, receiver
G3U99_17115	COG2205	protein histidine kinase activity
G3U99_17120	COG0784	Response regulator, receiver
G3U99_17120	COG2205	protein histidine kinase activity
G3U99_17125	COG0612	Peptidase, M16
G3U99_17135	COG0798	PFAM Bile acid sodium symporter
G3U99_17165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G3U99_17195	COG1063	alcohol dehydrogenase
G3U99_17200	COG0156	8-amino-7-oxononanoate synthase activity
G3U99_17205	COG2200	EAL domain
G3U99_17205	COG2199	diguanylate cyclase activity
G3U99_17205	COG2202	Pas domain
G3U99_17225	COG0346	lactoylglutathione lyase activity
G3U99_17235	COG4452	Inner membrane protein CreD
G3U99_17240	COG2205	protein histidine kinase activity
G3U99_17245	COG0745	RESPONSE REGULATOR receiver
G3U99_17255	COG0745	RESPONSE REGULATOR receiver
G3U99_17260	COG2205	protein histidine kinase activity
G3U99_17275	COG0667	Aldo Keto reductase
G3U99_17280	COG0583	DNA-binding transcription factor activity
G3U99_17295	COG0714	Associated with various cellular activities
G3U99_17310	COG2304	oxidoreductase activity
G3U99_17315	COG2304	oxidoreductase activity
G3U99_17335	COG0110	maltose O-acetyltransferase activity
G3U99_17340	COG1765	OsmC-like protein
G3U99_17345	COG0673	inositol 2-dehydrogenase activity
G3U99_17365	COG0531	amino acid
G3U99_17385	COG2205	protein histidine kinase activity
G3U99_17390	COG0745	RESPONSE REGULATOR receiver
G3U99_17415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_17420	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G3U99_17425	COG0402	S-adenosylhomocysteine deaminase activity
G3U99_17430	COG0861	Integral membrane protein TerC family
G3U99_17440	COG0784	Response regulator, receiver
G3U99_17440	COG2205	protein histidine kinase activity
G3U99_17440	COG5002	protein histidine kinase activity
G3U99_17480	COG3833	ABC-type maltose transport systems, permease component
G3U99_17485	COG1175	transmembrane transport
G3U99_17495	COG3842	ATPase activity
G3U99_17500	COG2096	Adenosyltransferase
G3U99_17505	COG0748	coenzyme F420 binding
G3U99_17510	COG3721	Heme iron utilization protein
G3U99_17520	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
G3U99_17525	COG0811	peptide transport
G3U99_17530	COG0848	biopolymer transport protein
G3U99_17540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3U99_17545	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
G3U99_17550	COG2814	Major facilitator Superfamily
G3U99_17560	COG0739	heme binding
G3U99_17575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G3U99_17585	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
G3U99_17595	COG0513	Belongs to the DEAD box helicase family
G3U99_17605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3U99_17605	COG4191	Histidine kinase
G3U99_17610	COG0784	Response regulator, receiver
G3U99_17610	COG3437	response regulator, receiver
G3U99_17615	COG1609	Transcriptional regulator
G3U99_17620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3U99_17625	COG1879	ABC-type sugar transport system periplasmic component
G3U99_17630	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3U99_17635	COG1129	ABC transporter
G3U99_17640	COG1869	D-ribose catabolic process
G3U99_17650	COG3469	chitinase activity
G3U99_17665	COG0004	ammonium transporteR
G3U99_17690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3U99_17710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3U99_17715	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
G3U99_17745	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
G3U99_17750	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
G3U99_17755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G3U99_17760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3U99_17780	COG1609	Transcriptional regulator
G3U99_17785	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G3U99_17790	COG3265	gluconokinase activity
G3U99_17795	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3U99_17805	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G3U99_17830	COG0583	DNA-binding transcription factor activity
G3U99_17850	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G3U99_17860	COG0668	transmembrane transport
G3U99_17880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G3U99_17920	COG3118	belongs to the thioredoxin family
G3U99_17925	COG4232	protein-disulfide reductase activity
G3U99_17940	COG1280	lysine exporter protein (LysE YggA)
G3U99_17970	COG0443	Heat shock 70 kDa protein
G3U99_17975	COG0583	DNA-binding transcription factor activity
G3U99_17985	COG4948	Mandelate Racemase Muconate Lactonizing
G3U99_17990	COG1396	sequence-specific DNA binding
G3U99_17995	COG5001	Diguanylate cyclase
G3U99_18005	COG3706	GGDEF domain
G3U99_18015	COG0642	Histidine kinase
G3U99_18020	COG0745	RESPONSE REGULATOR receiver
G3U99_18035	COG2130	NADP-dependent
G3U99_18090	COG0366	Alpha amylase catalytic
G3U99_18120	COG3279	Response regulator of the LytR AlgR family
G3U99_18125	COG3275	phosphorelay sensor kinase activity
G3U99_18140	COG4591	ABC-type transport system involved in lipoprotein release permease component
G3U99_18145	COG1136	(ABC) transporter
G3U99_18180	COG3530	Putative quorum-sensing-regulated virulence factor
G3U99_18195	COG1686	Belongs to the peptidase S11 family
G3U99_18210	COG3036	rescue of stalled ribosome
G3U99_18215	COG1278	Cold shock
G3U99_18230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G3U99_18230	COG1017	nitric oxide dioxygenase activity
G3U99_18235	COG3604	Transcriptional regulator
G3U99_18245	COG0546	phosphoglycolate phosphatase activity
G3U99_18250	COG2249	NAD(P)H dehydrogenase (quinone) activity
G3U99_18260	COG0534	Mate efflux family protein
G3U99_18270	COG0697	spore germination
G3U99_18285	COG2814	Major facilitator Superfamily
G3U99_18290	COG0583	DNA-binding transcription factor activity
G3U99_18295	COG5001	Diguanylate cyclase
G3U99_18370	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
G3U99_18405	COG0438	transferase activity, transferring glycosyl groups
G3U99_18410	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G3U99_18415	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G3U99_18420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G3U99_18425	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
G3U99_18435	COG3706	GGDEF domain
G3U99_18435	COG2203	Gaf domain
G3U99_18435	COG4251	negative regulation of phosphorylation
G3U99_18435	COG5001	Diguanylate cyclase
G3U99_18440	COG4989	oxidoreductase activity
G3U99_18450	COG0366	Alpha amylase catalytic
G3U99_18460	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G3U99_18465	COG1126	abc transporter atp-binding protein
G3U99_18470	COG0765	amino acid transport
G3U99_18475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3U99_18480	COG0765	amino acid transport
G3U99_18485	COG0109	protoheme IX farnesyltransferase activity
G3U99_18490	COG1612	heme a metabolic process
G3U99_18515	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
G3U99_18520	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G3U99_18525	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G3U99_18530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3U99_18570	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G3U99_18610	COG1741	Belongs to the pirin family
G3U99_18620	COG2814	Major facilitator Superfamily
G3U99_18625	COG1686	Belongs to the peptidase S11 family
G3U99_18630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G3U99_18635	COG0583	DNA-binding transcription factor activity
G3U99_18670	COG1253	flavin adenine dinucleotide binding
G3U99_18710	COG1280	lysine exporter protein (LysE YggA)
G3U99_18715	COG0583	DNA-binding transcription factor activity
G3U99_18770	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G3U99_18780	COG0523	cobalamin synthesis protein
G3U99_18785	COG2988	succinylglutamate desuccinylase activity
G3U99_18790	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
G3U99_18830	COG1846	Transcriptional regulator
G3U99_18840	COG1280	lysine exporter protein (LysE YggA)
G3U99_18855	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3U99_18860	COG3842	ATPase activity
G3U99_18865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3U99_18870	COG2423	ornithine cyclodeaminase activity
G3U99_18885	COG3938	Belongs to the proline racemase family
G3U99_18895	COG2186	Transcriptional regulator
G3U99_18910	COG0601	transmembrane transport
G3U99_18915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3U99_18930	COG0006	proline dipeptidase activity
G3U99_18975	COG3568	Endonuclease Exonuclease Phosphatase
G3U99_18985	COG3291	Pkd domain containing protein
G3U99_18990	COG0513	Belongs to the DEAD box helicase family
G3U99_19025	COG1376	ErfK ybiS ycfS ynhG family protein
G3U99_19025	COG1388	LysM domain
G3U99_19030	COG0415	Belongs to the DNA photolyase family
G3U99_19035	COG0789	Transcriptional regulator
G3U99_19040	COG3272	Protein of unknown function (DUF1722)
G3U99_19045	COG0813	purine-nucleoside phosphorylase activity
G3U99_19060	COG3706	GGDEF domain
G3U99_19075	COG1566	PFAM secretion protein HlyD family protein
G3U99_19080	COG0786	glutamate:sodium symporter activity
G3U99_19090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G3U99_19105	COG0583	DNA-binding transcription factor activity
G3U99_19115	COG1132	(ABC) transporter
G3U99_19160	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G3U99_19170	COG0259	pyridoxamine-phosphate oxidase activity
G3U99_19200	COG3033	Beta-eliminating lyase
G3U99_19205	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
G3U99_19210	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G3U99_19215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3U99_19225	COG1999	signal sequence binding
G3U99_19240	COG1671	Belongs to the UPF0178 family
G3U99_19245	COG0393	Putative heavy-metal-binding
G3U99_19250	COG0583	DNA-binding transcription factor activity
G3U99_19255	COG2814	Major facilitator Superfamily
G3U99_19275	COG0584	glycerophosphoryl diester phosphodiesterase
G3U99_19280	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3U99_19290	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3U99_19305	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_19310	COG0583	DNA-binding transcription factor activity
G3U99_19330	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G3U99_19485	COG1301	dicarboxylic acid transport
G3U99_19505	COG1404	Belongs to the peptidase S8 family
G3U99_19515	COG2207	Transcriptional regulator
G3U99_19525	COG0700	Nucleoside recognition
G3U99_19530	COG3366	ferrous iron transmembrane transporter activity
G3U99_19535	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G3U99_19550	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
G3U99_19560	COG0745	RESPONSE REGULATOR receiver
G3U99_19565	COG5002	protein histidine kinase activity
G3U99_19580	COG3437	response regulator, receiver
G3U99_19580	COG3850	Histidine kinase
G3U99_19580	COG4999	Histidine kinase
G3U99_19580	COG2205	protein histidine kinase activity
G3U99_19585	COG0745	RESPONSE REGULATOR receiver
G3U99_19590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_19595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3U99_19600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G3U99_19625	COG0745	RESPONSE REGULATOR receiver
G3U99_19630	COG2205	protein histidine kinase activity
G3U99_19635	COG0471	metal ion transport
G3U99_19675	COG1595	DNA-templated transcription, initiation
G3U99_19695	COG0251	oxidation-reduction process
G3U99_19705	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3U99_19705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3U99_19720	COG0604	alcohol dehydrogenase
G3U99_19760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3U99_19770	COG1175	transmembrane transport
G3U99_19795	COG0438	transferase activity, transferring glycosyl groups
G3U99_19805	COG0671	phosphoesterase, PA-phosphatase related
G3U99_19815	COG2207	Transcriptional regulator
G3U99_19815	COG3708	Transcriptional regulator
G3U99_19835	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G3U99_19840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3U99_19845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3U99_19850	COG1116	anion transmembrane transporter activity
G3U99_19855	COG0351	phosphomethylpyrimidine kinase
G3U99_19860	COG0656	L-ascorbic acid biosynthetic process
G3U99_19865	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_19865	COG0604	alcohol dehydrogenase
G3U99_19865	COG3321	synthase
G3U99_19880	COG0583	DNA-binding transcription factor activity
G3U99_19905	COG0840	transmembrane signaling receptor activity
G3U99_19910	COG0768	penicillin binding
G3U99_19915	COG2723	6-phospho-beta-galactosidase activity
G3U99_19925	COG0589	response to stress
G3U99_19930	COG3842	ATPase activity
G3U99_19935	COG0546	phosphoglycolate phosphatase activity
G3U99_19955	COG1175	transmembrane transport
G3U99_19960	COG0583	DNA-binding transcription factor activity
G3U99_19995	COG3321	synthase
G3U99_19995	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_19995	COG0604	alcohol dehydrogenase
G3U99_20005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3U99_20030	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G3U99_20075	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G3U99_20080	COG0840	transmembrane signaling receptor activity
G3U99_20085	COG0835	chemotaxis
G3U99_20110	COG0840	transmembrane signaling receptor activity
G3U99_20115	COG1444	tRNA N-acetyltransferase activity
G3U99_20145	COG4608	Belongs to the ABC transporter superfamily
G3U99_20150	COG0444	Belongs to the ABC transporter superfamily
G3U99_20185	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_20195	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_20200	COG1733	regulation of RNA biosynthetic process
G3U99_20220	COG0583	DNA-binding transcription factor activity
G3U99_20225	COG1051	belongs to the nudix hydrolase family
G3U99_20240	COG3300	MHYT domain
G3U99_20240	COG5001	Diguanylate cyclase
G3U99_20245	COG0697	spore germination
G3U99_20250	COG1846	Transcriptional regulator
G3U99_20280	COG1288	antiporter activity
G3U99_20285	COG0583	DNA-binding transcription factor activity
G3U99_20295	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G3U99_20300	COG3960	tartronate-semialdehyde synthase activity
G3U99_20305	COG3622	Belongs to the hyi family
G3U99_20310	COG2084	Dehydrogenase
G3U99_20325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G3U99_20345	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G3U99_20355	COG1733	regulation of RNA biosynthetic process
G3U99_20365	COG4974	Belongs to the 'phage' integrase family
G3U99_20375	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3U99_20400	COG0831	urea catabolic process
G3U99_20405	COG0832	Belongs to the urease beta subunit family
G3U99_20410	COG0804	urea catabolic process
G3U99_20415	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
G3U99_20460	COG0840	transmembrane signaling receptor activity
G3U99_20480	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G3U99_20490	COG4145	pantothenate transmembrane transporter activity
G3U99_20495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3U99_20500	COG0800	Aldolase
G3U99_20510	COG2706	6-phosphogluconolactonase activity
G3U99_20515	COG0251	oxidation-reduction process
G3U99_20520	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G3U99_20525	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G3U99_20530	COG1845	cytochrome c oxidase, subunit III
G3U99_20535	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G3U99_20540	COG0109	protoheme IX farnesyltransferase activity
G3U99_20590	COG0583	DNA-binding transcription factor activity
G3U99_20605	COG2205	protein histidine kinase activity
G3U99_20620	COG3214	Protein conserved in bacteria
G3U99_20625	COG0596	Alpha beta hydrolase
G3U99_20640	COG2252	PERMEase
G3U99_20660	COG4266	Belongs to the allantoicase family
G3U99_20665	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
G3U99_20675	COG0840	transmembrane signaling receptor activity
G3U99_20685	COG1522	sequence-specific DNA binding
G3U99_20695	COG0784	Response regulator, receiver
G3U99_20695	COG2205	protein histidine kinase activity
G3U99_20695	COG5002	protein histidine kinase activity
G3U99_20700	COG2226	methyltransferase
G3U99_20705	COG0402	S-adenosylhomocysteine deaminase activity
G3U99_20715	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3U99_20725	COG2186	Transcriptional regulator
G3U99_20750	COG3795	YCII-related domain
G3U99_20780	COG0402	S-adenosylhomocysteine deaminase activity
G3U99_20785	COG1404	Belongs to the peptidase S8 family
G3U99_20790	COG1335	isochorismatase
G3U99_20795	COG2207	Transcriptional regulator
G3U99_20830	COG0456	acetyltransferase
G3U99_20840	COG2909	trisaccharide binding
G3U99_20845	COG0058	SHG alpha-glucan phosphorylase activity
G3U99_20850	COG1640	4-alpha-glucanotransferase
G3U99_20855	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G3U99_20870	COG1619	proteins homologs of microcin C7 resistance protein MccF
G3U99_20910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3U99_20925	COG2249	NAD(P)H dehydrogenase (quinone) activity
G3U99_20935	COG0583	DNA-binding transcription factor activity
G3U99_20945	COG0300	oxidoreductase activity
G3U99_21000	COG0561	phosphatase activity
G3U99_21040	COG1132	(ABC) transporter
G3U99_21045	COG1132	(ABC) transporter
G3U99_21050	COG1021	2,3-dihydroxybenzoate-AMP ligase
G3U99_21055	COG1169	isochorismate synthase
G3U99_21075	COG3433	isochorismatase activity
G3U99_21075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3U99_21075	COG2226	methyltransferase
G3U99_21080	COG2814	Major facilitator Superfamily
G3U99_21085	COG4771	TonB-dependent receptor
G3U99_21090	COG4977	sequence-specific DNA binding
G3U99_21090	COG1917	Cupin 2, conserved barrel domain protein
G3U99_21110	COG1733	regulation of RNA biosynthetic process
G3U99_21170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3U99_21175	COG0383	alpha-mannosidase activity
G3U99_21185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3U99_21185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3U99_21185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3U99_21190	COG4969	Belongs to the N-Me-Phe pilin family
G3U99_21205	COG1120	ATPase activity
G3U99_21220	COG4264	IucA IucC family
G3U99_21245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G3U99_21255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3U99_21265	COG0662	Cupin 2, conserved barrel domain protein
G3U99_21270	COG1960	acyl-CoA dehydrogenase activity
G3U99_21275	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G3U99_21280	COG2076	Multidrug Resistance protein
G3U99_21285	COG2076	Multidrug Resistance protein
G3U99_21290	COG0590	tRNA wobble adenosine to inosine editing
G3U99_21355	COG3448	diguanylate cyclase activity
G3U99_21355	COG4175	Glycine betaine
G3U99_21360	COG4176	ABC-type proline glycine betaine transport system permease component
G3U99_21380	COG2095	MarC family integral membrane protein
G3U99_21390	COG0534	Mate efflux family protein
G3U99_21400	COG0583	DNA-binding transcription factor activity
G3U99_21425	COG4964	Belongs to the GSP D family
G3U99_21435	COG2894	cell division
G3U99_21490	COG1477	protein flavinylation
G3U99_21510	COG4221	oxidoreductase activity
G3U99_21515	COG0840	transmembrane signaling receptor activity
G3U99_21525	COG0573	inorganic phosphate transmembrane transporter activity
G3U99_21530	COG0581	inorganic phosphate transmembrane transporter activity
G3U99_21535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G3U99_21550	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
G3U99_21555	COG1162	GTPase activity
G3U99_21575	COG1122	ATPase activity
G3U99_21580	COG4720	Psort location CytoplasmicMembrane, score
G3U99_21600	COG0454	-acetyltransferase
G3U99_21605	COG0840	transmembrane signaling receptor activity
G3U99_21635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G3U99_21640	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G3U99_21645	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
G3U99_21685	COG3608	succinylglutamate desuccinylase aspartoacylase
G3U99_21690	COG1288	antiporter activity
G3U99_21705	COG0745	RESPONSE REGULATOR receiver
G3U99_21750	COG0583	DNA-binding transcription factor activity
G3U99_21755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G3U99_21760	COG1151	hydroxylamine reductase activity
G3U99_21770	COG3706	GGDEF domain
G3U99_21775	COG0583	DNA-binding transcription factor activity
G3U99_21790	COG3604	Transcriptional regulator
G3U99_21820	COG0415	Belongs to the DNA photolyase family
G3U99_21835	COG2329	Antibiotic biosynthesis monooxygenase
G3U99_21840	COG3304	Inner membrane component domain
G3U99_21865	COG1234	tRNA 3'-trailer cleavage
G3U99_21895	COG0004	ammonium transporteR
G3U99_21900	COG3437	response regulator, receiver
G3U99_21905	COG3383	formate dehydrogenase (NAD+) activity
G3U99_21910	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3U99_21915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3U99_21920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3U99_21945	COG0739	heme binding
G3U99_21950	COG3047	cAMP biosynthetic process
G3U99_21975	COG0300	oxidoreductase activity
G3U99_21980	COG5553	Cysteine dioxygenase type I
G3U99_21995	COG0673	inositol 2-dehydrogenase activity
G3U99_22000	COG0488	(ABC) transporter
G3U99_22030	COG4191	Histidine kinase
G3U99_22030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3U99_22035	COG1132	(ABC) transporter
G3U99_22055	COG0625	glutathione transferase activity
G3U99_22065	COG1690	Belongs to the RtcB family
G3U99_22070	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
G3U99_22095	COG3541	Predicted nucleotidyltransferase
G3U99_22100	COG1690	Belongs to the RtcB family
G3U99_22120	COG4650	regulator
G3U99_22135	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G3U99_22145	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G3U99_22160	COG4580	involved in the transport of maltose and maltodextrins
G3U99_22170	COG0840	transmembrane signaling receptor activity
G3U99_22200	COG0840	transmembrane signaling receptor activity
G3U99_22230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3U99_22240	COG0415	Belongs to the DNA photolyase family
G3U99_22260	COG0697	spore germination
G3U99_22285	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G3U99_22285	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G3U99_22295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G3U99_22295	COG2207	Transcriptional regulator
G3U99_22300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3U99_22320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3U99_22330	COG1522	sequence-specific DNA binding
G3U99_22355	COG1357	PFAM Pentapeptide repeats (8 copies)
G3U99_22365	COG1294	oxidase, subunit
G3U99_22370	COG1271	oxidase subunit
G3U99_22375	COG1805	sodium ion transport
G3U99_22400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G3U99_22425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3U99_22435	COG1309	transcriptional regulator
G3U99_22455	COG0745	RESPONSE REGULATOR receiver
G3U99_22460	COG5002	protein histidine kinase activity
G3U99_22495	COG0842	Transport permease protein
G3U99_22545	COG0110	maltose O-acetyltransferase activity
G3U99_22550	COG0346	lactoylglutathione lyase activity
G3U99_22555	COG0625	glutathione transferase activity
G3U99_22560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3U99_22570	COG0366	Alpha amylase catalytic
G3U99_22590	COG2084	Dehydrogenase
G3U99_22605	COG2130	NADP-dependent
G3U99_22610	COG1309	transcriptional regulator
G3U99_22615	COG3706	GGDEF domain
G3U99_22635	COG0513	Belongs to the DEAD box helicase family
G3U99_22645	COG3447	MASE1 domain protein
G3U99_22645	COG5001	Diguanylate cyclase
G3U99_22645	COG5002	protein histidine kinase activity
G3U99_22650	COG1574	metal-dependent hydrolase with the TIM-barrel fold
G3U99_22675	COG2204	response regulator
G3U99_22690	COG0573	inorganic phosphate transmembrane transporter activity
G3U99_22700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G3U99_22715	COG1175	transmembrane transport
G3U99_22720	COG0395	ABC-type sugar transport system, permease component
G3U99_22725	COG1554	hydrolase, family 65, central catalytic
G3U99_22730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3U99_22735	COG3842	ATPase activity
G3U99_22745	COG1621	beta-fructofuranosidase activity
G3U99_22755	COG0110	maltose O-acetyltransferase activity
G3U99_22785	COG0251	oxidation-reduction process
G3U99_22800	COG2356	endonuclease I
G3U99_22815	COG0564	pseudouridine synthase activity
G3U99_22840	COG0583	DNA-binding transcription factor activity
G3U99_22845	COG2814	Major facilitator Superfamily
G3U99_22875	COG0840	transmembrane signaling receptor activity
G3U99_22880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G3U99_22890	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G3U99_22900	COG0579	oxidoreductase
G3U99_22930	COG1012	belongs to the aldehyde dehydrogenase family
G3U99_22935	COG3284	Transcriptional regulator
G3U99_22955	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G3U99_22960	COG0363	glucosamine-6-phosphate deaminase activity
G3U99_22965	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G3U99_22970	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G3U99_22980	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G3U99_22990	COG2271	Major facilitator Superfamily
G3U99_22995	COG3851	Histidine kinase
G3U99_23000	COG2197	response regulator
G3U99_23025	COG3217	Mosc domain protein beta barrel domain protein
G3U99_23025	COG0633	Ferredoxin
G3U99_23025	COG0633	Ferredoxin
G3U99_23025	COG3217	Mosc domain protein beta barrel domain protein
G3U99_23035	COG1349	DNA-binding transcription factor activity
G3U99_23060	COG2354	Protein conserved in bacteria
G3U99_23070	COG0366	Alpha amylase catalytic
G3U99_23105	COG0840	transmembrane signaling receptor activity
G3U99_23110	COG1366	Belongs to the anti-sigma-factor antagonist family
G3U99_23120	COG2172	sigma factor antagonist activity
G3U99_23130	COG4999	Histidine kinase
G3U99_23130	COG3850	Histidine kinase
G3U99_23130	COG3437	response regulator, receiver
G3U99_23130	COG2205	protein histidine kinase activity
G3U99_23135	COG3437	response regulator, receiver
G3U99_23150	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G3U99_23150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G3U99_23155	COG0516	GMP reductase activity
G3U99_23160	COG0582	viral genome integration into host DNA
G3U99_23175	COG0563	adenylate kinase activity
G3U99_23305	COG3772	lysozyme
G3U99_23320	COG4695	Portal protein
G3U99_23360	COG4386	tail sheath protein
G3U99_23400	COG3646	Phage regulatory protein
G3U99_23450	COG1309	transcriptional regulator
G3U99_23475	COG4175	Glycine betaine
G3U99_23475	COG3448	diguanylate cyclase activity
G3U99_23495	COG1304	FMN binding
G3U99_23500	COG1620	l-lactate permease
G3U99_23505	COG0583	DNA-binding transcription factor activity
G3U99_23510	COG4172	Belongs to the ABC transporter superfamily
G3U99_23520	COG1067	ATP-dependent peptidase activity
G3U99_23525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3U99_23530	COG0840	transmembrane signaling receptor activity
G3U99_23545	COG4166	transmembrane transport
G3U99_23550	COG4174	ABC transporter (Permease)
G3U99_23555	COG4239	(ABC) transporter, permease
G3U99_23560	COG4172	Belongs to the ABC transporter superfamily
G3U99_23610	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3U99_23615	COG4605	iron ion homeostasis
G3U99_23620	COG4604	ABC transporter, ATP-binding protein
G3U99_23625	COG2759	Belongs to the formate--tetrahydrofolate ligase family
G3U99_23640	COG0004	ammonium transporteR
G3U99_23650	COG2271	Major facilitator Superfamily
G3U99_23660	COG0840	transmembrane signaling receptor activity
G3U99_23665	COG2203	Gaf domain
G3U99_23665	COG2199	diguanylate cyclase activity
G3U99_23675	COG0739	heme binding
G3U99_23715	COG3501	Rhs element vgr protein
G3U99_23740	COG0515	serine threonine protein kinase
G3U99_23740	COG2815	serine threonine protein kinase
G3U99_23775	COG1522	sequence-specific DNA binding
G3U99_23815	COG3250	beta-galactosidase activity
G3U99_23820	COG2211	Major facilitator Superfamily
G3U99_23825	COG1609	Transcriptional regulator
G3U99_23830	COG1309	transcriptional regulator
G3U99_23835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_23840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_23855	COG0183	Belongs to the thiolase family
G3U99_23870	COG1794	racemase activity, acting on amino acids and derivatives
G3U99_23875	COG2814	Major facilitator Superfamily
G3U99_23880	COG3240	lipase activity
G3U99_23930	COG1328	CTP reductase activity
G3U99_23935	COG0602	queuosine metabolic process
G3U99_23945	COG4067	protein conserved in archaea
G3U99_23945	COG0189	ligase activity
G3U99_23955	COG0545	Peptidyl-prolyl cis-trans isomerase
G3U99_23975	COG0247	lactate metabolic process
G3U99_23980	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
G3U99_23985	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G3U99_23990	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G3U99_23995	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G3U99_24020	COG2827	Endonuclease containing a URI domain
G3U99_24035	COG5002	protein histidine kinase activity
G3U99_24035	COG0784	Response regulator, receiver
G3U99_24060	COG1289	transmembrane transporter activity
G3U99_24065	COG0210	DNA helicase
G3U99_24085	COG0484	heat shock protein binding
G3U99_24095	COG3300	MHYT domain
G3U99_24095	COG5001	Diguanylate cyclase
G3U99_24100	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G3U99_24110	COG4181	ATPase activity
G3U99_24115	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G3U99_24120	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
G3U99_24125	COG1984	allophanate hydrolase subunit 2
G3U99_24135	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G3U99_24140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G3U99_24160	COG0243	molybdopterin cofactor binding
G3U99_24170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G3U99_24175	COG3850	Histidine kinase
G3U99_24180	COG2197	response regulator
G3U99_24185	COG3069	C4-dicarboxylate transmembrane transporter activity
G3U99_24205	COG3038	cytochrome b561
G3U99_24210	COG2353	YceI-like domain
G3U99_24215	COG2116	formate transmembrane transporter activity
G3U99_24220	COG0583	DNA-binding transcription factor activity
G3U99_24230	COG3593	DNA synthesis involved in DNA repair
G3U99_24235	COG0737	Belongs to the 5'-nucleotidase family
G3U99_24265	COG1605	Chorismate mutase
G3U99_24270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G3U99_24290	COG2050	protein possibly involved in aromatic compounds catabolism
G3U99_24315	COG0583	DNA-binding transcription factor activity
G3U99_24320	COG0045	succinate-CoA ligase (ADP-forming) activity
G3U99_24320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3U99_24320	COG1042	CoA-binding domain protein
G3U99_24325	COG3266	domain, Protein
G3U99_24330	COG1181	Belongs to the D-alanine--D-alanine ligase family
G3U99_24345	COG0023	Translation Initiation Factor
G3U99_24470	COG3140	Belongs to the UPF0181 family
G3U99_24485	COG0745	RESPONSE REGULATOR receiver
G3U99_24495	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
G3U99_24500	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
G3U99_24515	COG3706	GGDEF domain
G3U99_24520	COG5001	Diguanylate cyclase
G3U99_24520	COG4251	negative regulation of phosphorylation
G3U99_24520	COG3706	GGDEF domain
G3U99_24520	COG2203	Gaf domain
G3U99_24530	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G3U99_24535	COG4149	molybdate abc transporter
G3U99_24540	COG0725	ABC transporter, periplasmic molybdate-binding protein
G3U99_24545	COG1492	cobalamin metabolic process
G3U99_24560	COG1609	Transcriptional regulator
G3U99_24565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3U99_24565	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3U99_24570	COG1105	Belongs to the carbohydrate kinase PfkB family
G3U99_24575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3U99_24575	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
G3U99_24575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3U99_24580	COG3706	GGDEF domain
G3U99_24585	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G3U99_24590	COG2207	Transcriptional regulator
G3U99_24595	COG1979	alcohol dehydrogenase
G3U99_24610	COG2205	protein histidine kinase activity
G3U99_24610	COG2198	Histidine kinase
G3U99_24610	COG0784	Response regulator, receiver
G3U99_24615	COG1879	ABC-type sugar transport system periplasmic component
G3U99_24620	COG1803	Methylglyoxal synthase
G3U99_24625	COG2188	Transcriptional regulator
G3U99_24635	COG1263	PTS System
G3U99_24635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G3U99_24640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3U99_24645	COG0800	Aldolase
G3U99_24655	COG0546	phosphoglycolate phosphatase activity
G3U99_24670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3U99_24675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3U99_24685	COG0583	DNA-binding transcription factor activity
G3U99_24690	COG3048	D-serine ammonia-lyase activity
G3U99_24700	COG0346	lactoylglutathione lyase activity
G3U99_24715	COG0456	acetyltransferase
G3U99_24715	COG1214	PFAM Peptidase M22, glycoprotease
G3U99_24745	COG0513	Belongs to the DEAD box helicase family
G3U99_24755	COG0814	amino acid
G3U99_24760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3U99_24760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3U99_24770	COG0513	Belongs to the DEAD box helicase family
G3U99_24785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G3U99_24795	COG2897	thiosulfate sulfurtransferase activity
G3U99_24820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G3U99_24830	COG1522	sequence-specific DNA binding
G3U99_24840	COG0006	proline dipeptidase activity
G3U99_24845	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3U99_24850	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G3U99_24855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3U99_24860	COG1473	amidohydrolase
G3U99_24870	COG1522	sequence-specific DNA binding
G3U99_24890	COG2199	diguanylate cyclase activity
G3U99_24910	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G3U99_24920	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G3U99_24925	COG0523	cobalamin synthesis protein
G3U99_24930	COG0038	chloride channel
G3U99_24940	COG0156	8-amino-7-oxononanoate synthase activity
G3U99_24945	COG0784	Response regulator, receiver
G3U99_24945	COG2205	protein histidine kinase activity
G3U99_24950	COG0419	ATPase involved in DNA repair
G3U99_24960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3U99_24975	COG1192	Involved in chromosome partitioning
G3U99_25035	COG0745	RESPONSE REGULATOR receiver
G3U99_25040	COG2205	protein histidine kinase activity
G3U99_25060	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G3U99_25135	COG0671	phosphoesterase, PA-phosphatase related
G3U99_25160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3U99_25180	COG2986	histidine ammonia-lyase
G3U99_25190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3U99_25195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3U99_25220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3U99_25225	COG2814	Major facilitator Superfamily
G3U99_25240	COG0583	DNA-binding transcription factor activity
G3U99_25250	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G3U99_25270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3U99_25310	COG0583	DNA-binding transcription factor activity
G3U99_25315	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_25375	COG0384	phenazine biosynthesis protein PhzF
G3U99_25495	COG0251	oxidation-reduction process
G3U99_25505	COG0583	DNA-binding transcription factor activity
G3U99_25525	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G3U99_25580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3U99_25580	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
G3U99_25590	COG0583	DNA-binding transcription factor activity
G3U99_25615	COG0625	glutathione transferase activity
G3U99_25620	COG0583	DNA-binding transcription factor activity
G3U99_25645	COG1917	Cupin 2, conserved barrel domain protein
G3U99_25645	COG2207	Transcriptional regulator
G3U99_25655	COG4608	Belongs to the ABC transporter superfamily
G3U99_25660	COG0444	Belongs to the ABC transporter superfamily
G3U99_25665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3U99_25685	COG1609	Transcriptional regulator
G3U99_25695	COG4580	involved in the transport of maltose and maltodextrins
G3U99_25705	COG1472	Belongs to the glycosyl hydrolase 3 family
G3U99_25725	COG1609	Transcriptional regulator
G3U99_25735	COG4260	virion core protein, lumpy skin disease virus
G3U99_25765	COG1335	isochorismatase
G3U99_25770	COG2169	Transcriptional regulator
G3U99_25800	COG2267	carboxylic ester hydrolase activity
G3U99_25840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G3U99_25850	COG5001	Diguanylate cyclase
G3U99_25850	COG3706	GGDEF domain
G3U99_25850	COG2203	Gaf domain
G3U99_25850	COG4251	negative regulation of phosphorylation
G3U99_25885	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3U99_25930	COG2026	Addiction module toxin, RelE StbE family
G3U99_25970	COG1280	lysine exporter protein (LysE YggA)
G3U99_26065	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G3U99_26070	COG3434	signal transduction protein containing EAL and modified HD-GYP domains