locus-tag	class	description
JV59_00010	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JV59_00025	COG0165	Argininosuccinate lyase
JV59_00025	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JV59_00035	COG0251	oxidation-reduction process
JV59_00045	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JV59_00045	COG0678	peroxiredoxin activity
JV59_00055	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JV59_00100	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JV59_00105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JV59_00110	COG0546	phosphoglycolate phosphatase activity
JV59_00115	COG0180	Tryptophanyl-tRNA synthetase
JV59_00120	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JV59_00125	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JV59_00130	COG2205	protein histidine kinase activity
JV59_00135	COG0745	RESPONSE REGULATOR receiver
JV59_00140	COG3678	ATP-independent chaperone mediated protein folding
JV59_00145	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JV59_00150	COG0205	6-phosphofructokinase activity
JV59_00155	COG1285	pathogenesis
JV59_00165	COG1509	lysine 2,3-aminomutase activity
JV59_00170	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JV59_00175	COG1575	Belongs to the MenA family. Type 1 subfamily
JV59_00180	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JV59_00185	COG0534	Mate efflux family protein
JV59_00190	COG0149	triose-phosphate isomerase activity
JV59_00205	COG1072	(Pantothenic acid kinase))
JV59_00250	COG0085	RNA polymerase activity
JV59_00285	COG4942	peptidase
JV59_00290	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JV59_00300	COG0840	transmembrane signaling receptor activity
JV59_00305	COG0471	metal ion transport
JV59_00305	COG0490	domain, Protein
JV59_00315	COG1162	GTPase activity
JV59_00355	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JV59_00370	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JV59_00385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JV59_00390	COG0330	HflC and HflK could
JV59_00395	COG0330	HflC and HflK could
JV59_00450	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JV59_00550	COG0729	surface antigen
JV59_00650	COG2199	diguanylate cyclase activity
JV59_00650	COG2200	EAL domain
JV59_00695	COG1459	type II secretion system
JV59_00740	COG1077	Cell shape determining protein MreB Mrl
JV59_00745	COG1792	Involved in formation and maintenance of cell shape
JV59_00750	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JV59_00755	COG0424	maF-like protein
JV59_00760	COG1530	ribonuclease E activity
JV59_00765	COG3164	Protein of unknown function
JV59_00770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JV59_00775	COG0312	modulator of DNA gyrase
JV59_00845	COG2066	Belongs to the glutaminase family
JV59_00850	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JV59_00990	COG0762	integral membrane protein
JV59_00995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JV59_01000	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JV59_01025	COG0189	ligase activity
JV59_01030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JV59_01035	COG2356	endonuclease I
JV59_01040	COG3091	SprT-like family
JV59_01050	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JV59_01055	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JV59_01070	COG0191	fructose-bisphosphate aldolase activity
JV59_01075	COG0668	transmembrane transport
JV59_01080	COG0442	prolyl-tRNA aminoacylation
JV59_01090	COG0583	DNA-binding transcription factor activity
JV59_01100	COG3706	GGDEF domain
JV59_01110	COG0469	pyruvate kinase activity
JV59_01115	COG1349	DNA-binding transcription factor activity
JV59_01120	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JV59_01125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JV59_01130	COG3722	fumarate hydratase activity
JV59_01135	COG0246	Mannitol dehydrogenase
JV59_01140	COG2213	PTS system mannitol-specific
JV59_01140	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_01145	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JV59_01155	COG0142	geranyltranstransferase activity
JV59_01170	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JV59_01185	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JV59_01190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JV59_01210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JV59_01215	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
JV59_01220	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JV59_01225	COG0582	viral genome integration into host DNA
JV59_01265	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JV59_01280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JV59_01285	COG0358	DNA primase activity
JV59_01300	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JV59_01305	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JV59_01310	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JV59_01320	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JV59_01335	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JV59_01345	COG0585	pseudouridine synthase activity
JV59_01350	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JV59_01360	COG4942	peptidase
JV59_01360	COG1388	LysM domain
JV59_01365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JV59_01370	COG4536	flavin adenine dinucleotide binding
JV59_01375	COG4137	Cytochrome C assembly protein
JV59_01380	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JV59_01395	COG0336	Belongs to the RNA methyltransferase TrmD family
JV59_01410	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
JV59_01415	COG0237	dephospho-CoA kinase activity
JV59_01425	COG1459	type II secretion system
JV59_01430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JV59_01440	COG0157	Belongs to the NadC ModD family
JV59_01445	COG3023	N-Acetylmuramoyl-L-alanine amidase
JV59_01450	COG0716	FMN binding
JV59_01460	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JV59_01465	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JV59_01470	COG2186	Transcriptional regulator
JV59_01475	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JV59_01480	COG0508	dehydrogenase complex catalyzes the overall conversion of
JV59_01485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JV59_01500	COG0288	reversible hydration of carbon dioxide
JV59_01505	COG0659	secondary active sulfate transmembrane transporter activity
JV59_01510	COG1131	(ABC) transporter
JV59_01515	COG0842	Transport permease protein
JV59_01530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JV59_01555	COG1643	Atp-dependent helicase
JV59_01560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JV59_01565	COG1752	Esterase of the alpha-beta hydrolase superfamily
JV59_01570	COG1049	propionate catabolic process, 2-methylcitrate cycle
JV59_01585	COG0004	ammonium transporteR
JV59_01590	COG1840	ABC-type Fe3 transport system, periplasmic component
JV59_01600	COG3842	ATPase activity
JV59_01605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JV59_01620	COG2971	BadF BadG BcrA BcrD
JV59_01630	COG4608	Belongs to the ABC transporter superfamily
JV59_01635	COG0444	Belongs to the ABC transporter superfamily
JV59_01650	COG0747	negative chemotaxis
JV59_01660	COG2813	Specifically methylates the guanine in position
JV59_01665	COG0628	permease
JV59_01690	COG0739	heme binding
JV59_01695	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JV59_01705	COG2027	D-alanyl-D-alanine carboxypeptidase
JV59_01710	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JV59_01715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JV59_01725	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JV59_01730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JV59_01735	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JV59_01765	COG0513	Belongs to the DEAD box helicase family
JV59_01780	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JV59_01785	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JV59_01810	COG3153	acetyltransferase
JV59_01815	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JV59_01830	COG0779	Required for maturation of 30S ribosomal subunits
JV59_01835	COG0195	Participates in both transcription termination and antitermination
JV59_01860	COG0493	'glutamate synthase
JV59_01865	COG0070	glutamate synthase
JV59_01865	COG0067	glutamate synthase
JV59_01865	COG0069	glutamate synthase activity
JV59_01875	COG0069	glutamate synthase activity
JV59_01875	COG0070	glutamate synthase
JV59_01875	COG0067	glutamate synthase
JV59_01880	COG1242	4 iron, 4 sulfur cluster binding
JV59_01885	COG5001	Diguanylate cyclase
JV59_01885	COG2203	Gaf domain
JV59_01885	COG3706	GGDEF domain
JV59_01885	COG4251	negative regulation of phosphorylation
JV59_01890	COG2198	Histidine kinase
JV59_01890	COG5002	protein histidine kinase activity
JV59_01890	COG0784	Response regulator, receiver
JV59_01900	COG1538	Outer membrane efflux protein
JV59_01905	COG0494	nUDIX hydrolase
JV59_01910	COG3151	Protein conserved in bacteria
JV59_01920	COG3150	esterase
JV59_01925	COG0187	DNA topoisomerase II activity
JV59_01935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JV59_01940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JV59_01945	COG3105	Protein conserved in bacteria
JV59_01950	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JV59_01965	COG0723	plastoquinol--plastocyanin reductase activity
JV59_01970	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JV59_01975	COG2857	Cytochrome c1
JV59_01980	COG0625	glutathione transferase activity
JV59_01985	COG2969	positive regulation of protein catabolic process
JV59_01995	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JV59_02010	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JV59_02020	COG3116	cell division
JV59_02025	COG0768	penicillin binding
JV59_02030	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JV59_02035	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JV59_02040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JV59_02045	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JV59_02050	COG0772	Belongs to the SEDS family
JV59_02070	COG0849	cell division
JV59_02075	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JV59_02085	COG0653	protein targeting
JV59_02100	COG0505	Belongs to the CarA family
JV59_02145	COG1115	amino acid carrier protein
JV59_02160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JV59_02175	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JV59_02180	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JV59_02195	COG0560	Phosphoserine phosphatase
JV59_02205	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JV59_02210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JV59_02260	COG2813	Specifically methylates the guanine in position
JV59_02270	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JV59_02275	COG1805	sodium ion transport
JV59_02295	COG2871	sodium ion transport
JV59_02300	COG1477	protein flavinylation
JV59_02310	COG0745	RESPONSE REGULATOR receiver
JV59_02310	COG3706	GGDEF domain
JV59_02315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JV59_02320	COG0514	ATP-dependent DNA helicase (RecQ)
JV59_02340	COG0733	neurotransmitter:sodium symporter activity
JV59_02360	COG2195	Cleaves the N-terminal amino acid of tripeptides
JV59_02365	COG2252	PERMEase
JV59_02385	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JV59_02390	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JV59_02400	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JV59_02400	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JV59_02485	COG0750	zinc metalloprotease
JV59_02490	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JV59_02500	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JV59_02525	COG0587	DNA-directed DNA polymerase activity
JV59_02560	COG1388	LysM domain
JV59_02560	COG0741	lytic transglycosylase activity
JV59_02590	COG1960	acyl-CoA dehydrogenase activity
JV59_02625	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JV59_02645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JV59_02665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JV59_02665	COG1263	PTS System
JV59_02670	COG0366	Alpha amylase catalytic
JV59_02695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JV59_02750	COG0768	penicillin binding
JV59_02775	COG0495	leucyl-tRNA aminoacylation
JV59_02785	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JV59_02820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JV59_02930	COG0326	Molecular chaperone. Has ATPase activity
JV59_02960	COG2217	Heavy metal translocating P-type atpase
JV59_02960	COG2608	mercury ion transmembrane transporter activity
JV59_03220	COG2912	Transglutaminase-like superfamily
JV59_05005	COG3706	GGDEF domain
JV59_05345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JV59_05465	COG1609	Transcriptional regulator
JV59_05500	COG1609	Transcriptional regulator
JV59_06345	COG1929	Belongs to the glycerate kinase type-1 family
JV59_06435	COG0297	glycogen (starch) synthase activity
JV59_06470	COG0438	transferase activity, transferring glycosyl groups
JV59_06840	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JV59_06880	COG0589	response to stress
JV59_07555	COG0602	queuosine metabolic process
JV59_08285	COG2885	chlorophyll binding
JV59_08455	COG3040	lipid binding
JV59_08970	COG0009	L-threonylcarbamoyladenylate synthase
JV59_10105	COG0596	Alpha beta hydrolase
JV59_10720	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JV59_10845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JV59_11870	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JV59_13275	COG0646	methionine synthase
JV59_13275	COG1410	methionine synthase
JV59_13840	COG0540	Belongs to the ATCase OTCase family
JV59_13905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JV59_13965	COG1253	flavin adenine dinucleotide binding
JV59_14210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JV59_14260	COG4310	Domain of unknown function (DUF2172)
JV59_15940	COG0006	proline dipeptidase activity
JV59_15955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JV59_15960	COG0601	transmembrane transport
JV59_15975	COG2186	Transcriptional regulator
JV59_15985	COG3938	Belongs to the proline racemase family
JV59_16000	COG2423	ornithine cyclodeaminase activity
JV59_16005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JV59_16010	COG3842	ATPase activity
JV59_16015	COG1176	ABC-type spermidine putrescine transport system, permease component I
JV59_16030	COG1280	lysine exporter protein (LysE YggA)
JV59_16040	COG1846	Transcriptional regulator
JV59_16085	COG2988	succinylglutamate desuccinylase activity
JV59_16090	COG0523	cobalamin synthesis protein
JV59_16100	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JV59_16155	COG0583	DNA-binding transcription factor activity
JV59_16160	COG1280	lysine exporter protein (LysE YggA)
JV59_16200	COG1253	flavin adenine dinucleotide binding
JV59_16235	COG0583	DNA-binding transcription factor activity
JV59_16240	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JV59_16245	COG1686	Belongs to the peptidase S11 family
JV59_16250	COG2814	Major facilitator Superfamily
JV59_16260	COG1741	Belongs to the pirin family
JV59_16275	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JV59_16300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JV59_16340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JV59_16350	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JV59_16360	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JV59_16385	COG1612	heme a metabolic process
JV59_16390	COG0109	protoheme IX farnesyltransferase activity
JV59_16395	COG0765	amino acid transport
JV59_16400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JV59_16405	COG0765	amino acid transport
JV59_16410	COG1126	abc transporter atp-binding protein
JV59_16415	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JV59_16425	COG0366	Alpha amylase catalytic
JV59_16435	COG4989	oxidoreductase activity
JV59_16440	COG4251	negative regulation of phosphorylation
JV59_16440	COG5001	Diguanylate cyclase
JV59_16440	COG2203	Gaf domain
JV59_16440	COG3706	GGDEF domain
JV59_16455	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JV59_16460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JV59_16465	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JV59_16470	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JV59_16475	COG0438	transferase activity, transferring glycosyl groups
JV59_16490	COG1045	serine acetyltransferase
JV59_16500	COG0438	transferase activity, transferring glycosyl groups
JV59_16500	COG0297	glycogen (starch) synthase activity
JV59_16510	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JV59_16585	COG5001	Diguanylate cyclase
JV59_16590	COG0583	DNA-binding transcription factor activity
JV59_16595	COG2814	Major facilitator Superfamily
JV59_16610	COG0697	spore germination
JV59_16620	COG0534	Mate efflux family protein
JV59_16630	COG2249	NAD(P)H dehydrogenase (quinone) activity
JV59_16635	COG0546	phosphoglycolate phosphatase activity
JV59_16650	COG1017	nitric oxide dioxygenase activity
JV59_16650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JV59_16665	COG1278	Cold shock
JV59_16670	COG3036	rescue of stalled ribosome
JV59_16685	COG1686	Belongs to the peptidase S11 family
JV59_16700	COG3530	Putative quorum-sensing-regulated virulence factor
JV59_16720	COG1012	belongs to the aldehyde dehydrogenase family
JV59_16735	COG1136	(ABC) transporter
JV59_16740	COG4591	ABC-type transport system involved in lipoprotein release permease component
JV59_16755	COG3275	phosphorelay sensor kinase activity
JV59_16760	COG3279	Response regulator of the LytR AlgR family
JV59_16790	COG0366	Alpha amylase catalytic
JV59_16810	COG0747	negative chemotaxis
JV59_16815	COG4608	Belongs to the ABC transporter superfamily
JV59_16820	COG0444	Belongs to the ABC transporter superfamily
JV59_16825	COG0534	Mate efflux family protein
JV59_16830	COG0641	radical SAM
JV59_16850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JV59_16880	COG2130	NADP-dependent
JV59_16895	COG0745	RESPONSE REGULATOR receiver
JV59_16900	COG0642	Histidine kinase
JV59_16910	COG3706	GGDEF domain
JV59_16925	COG1396	sequence-specific DNA binding
JV59_16930	COG4948	Mandelate Racemase Muconate Lactonizing
JV59_16940	COG0583	DNA-binding transcription factor activity
JV59_16945	COG0443	Heat shock 70 kDa protein
JV59_16975	COG1280	lysine exporter protein (LysE YggA)
JV59_16990	COG4232	protein-disulfide reductase activity
JV59_16995	COG3118	belongs to the thioredoxin family
JV59_17035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JV59_17055	COG0668	transmembrane transport
JV59_17065	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JV59_17085	COG0583	DNA-binding transcription factor activity
JV59_17110	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JV59_17125	COG3265	gluconokinase activity
JV59_17130	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JV59_17135	COG1609	Transcriptional regulator
JV59_17155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JV59_17160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JV59_17165	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JV59_17170	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
JV59_17200	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JV59_17205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JV59_17225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JV59_17250	COG0004	ammonium transporteR
JV59_17265	COG3469	chitinase activity
JV59_17275	COG1869	D-ribose catabolic process
JV59_17280	COG1129	ABC transporter
JV59_17285	COG1172	Belongs to the binding-protein-dependent transport system permease family
JV59_17290	COG1879	ABC-type sugar transport system periplasmic component
JV59_17295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JV59_17300	COG1609	Transcriptional regulator
JV59_17305	COG3437	response regulator, receiver
JV59_17305	COG0784	Response regulator, receiver
JV59_17310	COG4191	Histidine kinase
JV59_17310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JV59_17320	COG0513	Belongs to the DEAD box helicase family
JV59_17330	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
JV59_17340	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JV59_17355	COG0739	heme binding
JV59_17365	COG2814	Major facilitator Superfamily
JV59_17370	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JV59_17375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JV59_17385	COG0848	biopolymer transport protein
JV59_17390	COG0811	peptide transport
JV59_17395	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JV59_17405	COG3721	Heme iron utilization protein
JV59_17410	COG0748	coenzyme F420 binding
JV59_17415	COG2096	Adenosyltransferase
JV59_17420	COG3842	ATPase activity
JV59_17430	COG1175	transmembrane transport
JV59_17475	COG2205	protein histidine kinase activity
JV59_17475	COG0784	Response regulator, receiver
JV59_17475	COG5002	protein histidine kinase activity
JV59_17485	COG0861	Integral membrane protein TerC family
JV59_17495	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JV59_17500	COG1566	PFAM secretion protein HlyD family protein
JV59_17525	COG0745	RESPONSE REGULATOR receiver
JV59_17530	COG2205	protein histidine kinase activity
JV59_17560	COG0531	amino acid
JV59_17580	COG0673	inositol 2-dehydrogenase activity
JV59_17585	COG1765	OsmC-like protein
JV59_17590	COG0110	maltose O-acetyltransferase activity
JV59_17610	COG2304	oxidoreductase activity
JV59_17615	COG2304	oxidoreductase activity
JV59_17630	COG0714	Associated with various cellular activities
JV59_17645	COG0583	DNA-binding transcription factor activity
JV59_17650	COG0667	Aldo Keto reductase
JV59_17665	COG2205	protein histidine kinase activity
JV59_17670	COG0745	RESPONSE REGULATOR receiver
JV59_17685	COG0745	RESPONSE REGULATOR receiver
JV59_17690	COG2205	protein histidine kinase activity
JV59_17695	COG4452	Inner membrane protein CreD
JV59_17705	COG0346	lactoylglutathione lyase activity
JV59_17725	COG2199	diguanylate cyclase activity
JV59_17725	COG2200	EAL domain
JV59_17725	COG2202	Pas domain
JV59_17730	COG0156	8-amino-7-oxononanoate synthase activity
JV59_17735	COG1063	alcohol dehydrogenase
JV59_17765	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JV59_17790	COG0798	PFAM Bile acid sodium symporter
JV59_17800	COG0612	Peptidase, M16
JV59_17805	COG2205	protein histidine kinase activity
JV59_17805	COG0784	Response regulator, receiver
JV59_17810	COG0784	Response regulator, receiver
JV59_17810	COG2205	protein histidine kinase activity
JV59_17830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JV59_17835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JV59_17840	COG3186	Phenylalanine-4-hydroxylase
JV59_17890	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JV59_17895	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JV59_17940	COG1454	alcohol dehydrogenase
JV59_17945	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
JV59_17955	COG1011	Hydrolase
JV59_17990	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JV59_18005	COG3842	ATPase activity
JV59_18035	COG2866	Carboxypeptidase
JV59_18040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JV59_18045	COG0583	DNA-binding transcription factor activity
JV59_18050	COG1760	l-serine dehydratase
JV59_18075	COG3706	GGDEF domain
JV59_18080	COG0835	chemotaxis
JV59_18080	COG0784	Response regulator, receiver
JV59_18085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JV59_18105	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_18115	COG0494	nUDIX hydrolase
JV59_18120	COG0714	Associated with various cellular activities
JV59_18125	COG2425	protein containing a von Willebrand factor type A (vWA) domain
JV59_18130	COG2814	Major facilitator Superfamily
JV59_18155	COG3706	GGDEF domain
JV59_18160	COG1846	Transcriptional regulator
JV59_18165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JV59_18170	COG2176	DNA-directed DNA polymerase activity
JV59_18180	COG0789	Transcriptional regulator
JV59_18190	COG5001	Diguanylate cyclase
JV59_18190	COG3300	MHYT domain
JV59_18195	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JV59_18205	COG2204	response regulator
JV59_18220	COG0515	serine threonine protein kinase
JV59_18220	COG2815	serine threonine protein kinase
JV59_18245	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JV59_18265	COG0583	DNA-binding transcription factor activity
JV59_18325	COG1716	ATPase activity
JV59_18325	COG5001	Diguanylate cyclase
JV59_18345	COG2910	NAD(P)H-binding
JV59_18350	COG0583	DNA-binding transcription factor activity
JV59_18355	COG1115	amino acid carrier protein
JV59_18370	COG1741	Belongs to the pirin family
JV59_18375	COG2259	Doxx family
JV59_18405	COG1024	Enoyl-CoA hydratase
JV59_18410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JV59_18415	COG1960	acyl-CoA dehydrogenase activity
JV59_18425	COG0183	Belongs to the thiolase family
JV59_18435	COG1960	acyl-CoA dehydrogenase activity
JV59_18440	COG1024	Enoyl-CoA hydratase
JV59_18445	COG1024	Enoyl-CoA hydratase
JV59_18455	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_18460	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
JV59_18480	COG3706	GGDEF domain
JV59_18505	COG2199	diguanylate cyclase activity
JV59_18505	COG2203	Gaf domain
JV59_18560	COG0243	molybdopterin cofactor binding
JV59_18565	COG1648	precorrin-2 dehydrogenase activity
JV59_18565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JV59_18570	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JV59_18580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JV59_18580	COG1116	anion transmembrane transporter activity
JV59_18585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JV59_18590	COG1116	anion transmembrane transporter activity
JV59_18595	COG2146	nitrite reductase [NAD(P)H] activity
JV59_18595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JV59_18600	COG2146	nitrite reductase [NAD(P)H] activity
JV59_18625	COG3118	belongs to the thioredoxin family
JV59_18630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JV59_18640	COG0419	ATPase involved in DNA repair
JV59_18645	COG0784	Response regulator, receiver
JV59_18645	COG2205	protein histidine kinase activity
JV59_18650	COG0156	8-amino-7-oxononanoate synthase activity
JV59_18660	COG0038	chloride channel
JV59_18665	COG0523	cobalamin synthesis protein
JV59_18680	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JV59_18700	COG2199	diguanylate cyclase activity
JV59_18715	COG1522	sequence-specific DNA binding
JV59_18720	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JV59_18725	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JV59_18750	COG2897	thiosulfate sulfurtransferase activity
JV59_18760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JV59_18775	COG0513	Belongs to the DEAD box helicase family
JV59_18785	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JV59_18785	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JV59_18790	COG0814	amino acid
JV59_18800	COG0513	Belongs to the DEAD box helicase family
JV59_18830	COG0456	acetyltransferase
JV59_18830	COG1214	PFAM Peptidase M22, glycoprotease
JV59_18845	COG0346	lactoylglutathione lyase activity
JV59_18855	COG3048	D-serine ammonia-lyase activity
JV59_18860	COG0583	DNA-binding transcription factor activity
JV59_18870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JV59_18875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JV59_18890	COG0546	phosphoglycolate phosphatase activity
JV59_18900	COG0800	Aldolase
JV59_18905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JV59_18910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JV59_18910	COG1263	PTS System
JV59_18920	COG2188	Transcriptional regulator
JV59_18925	COG1803	Methylglyoxal synthase
JV59_18930	COG1879	ABC-type sugar transport system periplasmic component
JV59_18935	COG2198	Histidine kinase
JV59_18935	COG2205	protein histidine kinase activity
JV59_18935	COG0784	Response regulator, receiver
JV59_18950	COG1979	alcohol dehydrogenase
JV59_18955	COG2207	Transcriptional regulator
JV59_18960	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JV59_18970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_18970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_18970	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JV59_18975	COG1105	Belongs to the carbohydrate kinase PfkB family
JV59_18980	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_18980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_18990	COG1609	Transcriptional regulator
JV59_19010	COG0725	ABC transporter, periplasmic molybdate-binding protein
JV59_19015	COG4149	molybdate abc transporter
JV59_19020	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JV59_19030	COG5001	Diguanylate cyclase
JV59_19030	COG4251	negative regulation of phosphorylation
JV59_19030	COG2203	Gaf domain
JV59_19030	COG3706	GGDEF domain
JV59_19035	COG3706	GGDEF domain
JV59_19050	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JV59_19055	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JV59_19065	COG0745	RESPONSE REGULATOR receiver
JV59_19090	COG0023	Translation Initiation Factor
JV59_19105	COG1181	Belongs to the D-alanine--D-alanine ligase family
JV59_19110	COG3266	domain, Protein
JV59_19115	COG1042	CoA-binding domain protein
JV59_19115	COG0045	succinate-CoA ligase (ADP-forming) activity
JV59_19115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JV59_19120	COG0583	DNA-binding transcription factor activity
JV59_19125	COG4771	TonB-dependent receptor
JV59_19125	COG1629	transport
JV59_19135	COG4533	DNA binding
JV59_19145	COG2050	protein possibly involved in aromatic compounds catabolism
JV59_19150	COG4783	chaperone-mediated protein folding
JV59_19165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JV59_19175	COG0840	transmembrane signaling receptor activity
JV59_19180	COG0784	Response regulator, receiver
JV59_19180	COG2205	protein histidine kinase activity
JV59_19185	COG0745	RESPONSE REGULATOR receiver
JV59_19200	COG1605	Chorismate mutase
JV59_19230	COG0737	Belongs to the 5'-nucleotidase family
JV59_19235	COG3593	DNA synthesis involved in DNA repair
JV59_19245	COG0583	DNA-binding transcription factor activity
JV59_19250	COG2116	formate transmembrane transporter activity
JV59_19255	COG2353	YceI-like domain
JV59_19260	COG3038	cytochrome b561
JV59_19280	COG3069	C4-dicarboxylate transmembrane transporter activity
JV59_19285	COG2197	response regulator
JV59_19290	COG3850	Histidine kinase
JV59_19295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JV59_19305	COG0243	molybdopterin cofactor binding
JV59_19315	COG3005	denitrification pathway
JV59_19320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JV59_19325	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JV59_19335	COG1984	allophanate hydrolase subunit 2
JV59_19340	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JV59_19345	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
JV59_19350	COG4181	ATPase activity
JV59_19360	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JV59_19365	COG3300	MHYT domain
JV59_19365	COG5001	Diguanylate cyclase
JV59_19375	COG0484	heat shock protein binding
JV59_19395	COG0210	DNA helicase
JV59_19400	COG1289	transmembrane transporter activity
JV59_19425	COG0784	Response regulator, receiver
JV59_19425	COG5002	protein histidine kinase activity
JV59_19440	COG2827	Endonuclease containing a URI domain
JV59_19465	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JV59_19470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JV59_19475	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JV59_19480	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
JV59_19485	COG0247	lactate metabolic process
JV59_19505	COG0545	Peptidyl-prolyl cis-trans isomerase
JV59_19515	COG0189	ligase activity
JV59_19515	COG4067	protein conserved in archaea
JV59_19525	COG0602	queuosine metabolic process
JV59_19530	COG1328	CTP reductase activity
JV59_19575	COG3291	Pkd domain containing protein
JV59_19575	COG4412	M6 family metalloprotease domain protein
JV59_19585	COG2814	Major facilitator Superfamily
JV59_19590	COG1794	racemase activity, acting on amino acids and derivatives
JV59_19605	COG0183	Belongs to the thiolase family
JV59_19620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_19625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_19630	COG1309	transcriptional regulator
JV59_19635	COG1609	Transcriptional regulator
JV59_19645	COG3250	beta-galactosidase activity
JV59_19720	COG0515	serine threonine protein kinase
JV59_19720	COG2815	serine threonine protein kinase
JV59_19745	COG3501	Rhs element vgr protein
JV59_19780	COG0739	heme binding
JV59_19790	COG2203	Gaf domain
JV59_19790	COG2199	diguanylate cyclase activity
JV59_19795	COG0840	transmembrane signaling receptor activity
JV59_19805	COG2271	Major facilitator Superfamily
JV59_19825	COG4206	TonB-dependent receptor
JV59_19835	COG0004	ammonium transporteR
JV59_19850	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JV59_19855	COG4604	ABC transporter, ATP-binding protein
JV59_19860	COG4605	iron ion homeostasis
JV59_19865	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JV59_19905	COG3706	GGDEF domain
JV59_19905	COG0745	RESPONSE REGULATOR receiver
JV59_19915	COG4172	Belongs to the ABC transporter superfamily
JV59_19920	COG4239	(ABC) transporter, permease
JV59_19925	COG4174	ABC transporter (Permease)
JV59_19930	COG4166	transmembrane transport
JV59_19945	COG0840	transmembrane signaling receptor activity
JV59_19950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JV59_19955	COG1067	ATP-dependent peptidase activity
JV59_19965	COG4172	Belongs to the ABC transporter superfamily
JV59_19970	COG0583	DNA-binding transcription factor activity
JV59_19975	COG1620	l-lactate permease
JV59_20000	COG3448	diguanylate cyclase activity
JV59_20000	COG4175	Glycine betaine
JV59_20025	COG1309	transcriptional regulator
JV59_20045	COG1346	cytolysis
JV59_20055	COG0516	GMP reductase activity
JV59_20060	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JV59_20060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JV59_20075	COG3437	response regulator, receiver
JV59_20080	COG4999	Histidine kinase
JV59_20080	COG3850	Histidine kinase
JV59_20080	COG3437	response regulator, receiver
JV59_20080	COG2205	protein histidine kinase activity
JV59_20090	COG2172	sigma factor antagonist activity
JV59_20100	COG1366	Belongs to the anti-sigma-factor antagonist family
JV59_20105	COG0840	transmembrane signaling receptor activity
JV59_20140	COG0366	Alpha amylase catalytic
JV59_20150	COG2354	Protein conserved in bacteria
JV59_20175	COG1349	DNA-binding transcription factor activity
JV59_20185	COG3217	Mosc domain protein beta barrel domain protein
JV59_20185	COG0633	Ferredoxin
JV59_20185	COG0633	Ferredoxin
JV59_20185	COG3217	Mosc domain protein beta barrel domain protein
JV59_20210	COG2197	response regulator
JV59_20215	COG3851	Histidine kinase
JV59_20220	COG2271	Major facilitator Superfamily
JV59_20240	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JV59_20245	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JV59_20250	COG0363	glucosamine-6-phosphate deaminase activity
JV59_20255	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JV59_20275	COG3284	Transcriptional regulator
JV59_20280	COG1012	belongs to the aldehyde dehydrogenase family
JV59_20310	COG0579	oxidoreductase
JV59_20320	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JV59_20330	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JV59_20335	COG0840	transmembrane signaling receptor activity
JV59_20360	COG2814	Major facilitator Superfamily
JV59_20365	COG0583	DNA-binding transcription factor activity
JV59_20395	COG0564	pseudouridine synthase activity
JV59_20425	COG0251	oxidation-reduction process
JV59_20460	COG0110	maltose O-acetyltransferase activity
JV59_20470	COG1621	beta-fructofuranosidase activity
JV59_20485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JV59_20490	COG1554	hydrolase, family 65, central catalytic
JV59_20495	COG0395	ABC-type sugar transport system, permease component
JV59_20515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JV59_20525	COG0573	inorganic phosphate transmembrane transporter activity
JV59_20565	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JV59_20570	COG3447	MASE1 domain protein
JV59_20570	COG5002	protein histidine kinase activity
JV59_20570	COG5001	Diguanylate cyclase
JV59_20580	COG0513	Belongs to the DEAD box helicase family
JV59_20600	COG3706	GGDEF domain
JV59_20605	COG1309	transcriptional regulator
JV59_20610	COG2130	NADP-dependent
JV59_20625	COG2084	Dehydrogenase
JV59_20645	COG0366	Alpha amylase catalytic
JV59_20655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JV59_20660	COG0625	glutathione transferase activity
JV59_20665	COG0346	lactoylglutathione lyase activity
JV59_20715	COG1131	(ABC) transporter
JV59_20720	COG0842	Transport permease protein
JV59_20755	COG5002	protein histidine kinase activity
JV59_20760	COG0745	RESPONSE REGULATOR receiver
JV59_20780	COG1309	transcriptional regulator
JV59_20790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JV59_20795	COG2813	Specifically methylates the guanine in position
JV59_20815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JV59_20835	COG1805	sodium ion transport
JV59_20840	COG1271	oxidase subunit
JV59_20845	COG1294	oxidase, subunit
JV59_20860	COG0719	Fe-S assembly protein
JV59_20865	COG0396	ATPase activity
JV59_20870	COG0719	Fe-S assembly protein
JV59_20875	COG0316	Belongs to the HesB IscA family
JV59_20885	COG1780	Probably involved in ribonucleotide reductase function
JV59_20890	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JV59_20900	COG1357	PFAM Pentapeptide repeats (8 copies)
JV59_20905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JV59_20905	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JV59_20925	COG1522	sequence-specific DNA binding
JV59_20935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JV59_20955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JV59_20960	COG2207	Transcriptional regulator
JV59_20960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JV59_20970	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JV59_20970	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JV59_20995	COG0697	spore germination
JV59_21015	COG0415	Belongs to the DNA photolyase family
JV59_21055	COG0840	transmembrane signaling receptor activity
JV59_21080	COG0583	DNA-binding transcription factor activity
JV59_21095	COG0840	transmembrane signaling receptor activity
JV59_21105	COG4580	involved in the transport of maltose and maltodextrins
JV59_21120	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JV59_21135	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JV59_21160	COG0583	DNA-binding transcription factor activity
JV59_21170	COG1132	(ABC) transporter
JV59_21175	COG0589	response to stress
JV59_21185	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JV59_21185	COG2111	Na H antiporter
JV59_21190	COG1006	Multisubunit Na H antiporter MnhC subunit
JV59_21205	COG2212	antiporter activity
JV59_21210	COG1320	monovalent cation:proton antiporter activity
JV59_21215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JV59_21215	COG4191	Histidine kinase
JV59_21255	COG0488	(ABC) transporter
JV59_21260	COG0673	inositol 2-dehydrogenase activity
JV59_21275	COG5553	Cysteine dioxygenase type I
JV59_21280	COG0300	oxidoreductase activity
JV59_21305	COG3047	cAMP biosynthetic process
JV59_21310	COG0739	heme binding
JV59_21335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JV59_21340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JV59_21350	COG3383	formate dehydrogenase (NAD+) activity
JV59_21390	COG1234	tRNA 3'-trailer cleavage
JV59_21395	COG0583	DNA-binding transcription factor activity
JV59_21405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JV59_21415	COG3304	Inner membrane component domain
JV59_21420	COG2329	Antibiotic biosynthesis monooxygenase
JV59_21430	COG3046	protein related to deoxyribodipyrimidine photolyase
JV59_21435	COG0415	Belongs to the DNA photolyase family
JV59_21460	COG3604	Transcriptional regulator
JV59_21480	COG0583	DNA-binding transcription factor activity
JV59_21490	COG1151	hydroxylamine reductase activity
JV59_21495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JV59_21520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JV59_21545	COG0745	RESPONSE REGULATOR receiver
JV59_21550	COG3850	Histidine kinase
JV59_21550	COG5002	protein histidine kinase activity
JV59_21560	COG1288	antiporter activity
JV59_21565	COG3608	succinylglutamate desuccinylase aspartoacylase
JV59_21595	COG1522	sequence-specific DNA binding
JV59_21605	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
JV59_21610	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JV59_21615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JV59_21670	COG0363	glucosamine-6-phosphate deaminase activity
JV59_21675	COG4720	Psort location CytoplasmicMembrane, score
JV59_21680	COG1122	ATPase activity
JV59_21700	COG1162	GTPase activity
JV59_21705	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JV59_21725	COG0581	inorganic phosphate transmembrane transporter activity
JV59_21730	COG0573	inorganic phosphate transmembrane transporter activity
JV59_21735	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JV59_21740	COG0840	transmembrane signaling receptor activity
JV59_21745	COG4221	oxidoreductase activity
JV59_21765	COG1477	protein flavinylation
JV59_21830	COG4964	Belongs to the GSP D family
JV59_21855	COG0583	DNA-binding transcription factor activity
JV59_21865	COG0534	Mate efflux family protein
JV59_21875	COG2095	MarC family integral membrane protein
JV59_21895	COG4176	ABC-type proline glycine betaine transport system permease component
JV59_21900	COG4175	Glycine betaine
JV59_21900	COG3448	diguanylate cyclase activity
JV59_21945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JV59_21945	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JV59_21955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JV59_21980	COG4264	IucA IucC family
JV59_21995	COG1120	ATPase activity
JV59_22000	COG2814	Major facilitator Superfamily
JV59_22010	COG4968	Prepilin-type N-terminal cleavage methylation domain
JV59_22015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_22015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_22015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_22025	COG0383	alpha-mannosidase activity
JV59_22030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_22055	COG1414	Transcriptional regulator
JV59_22090	COG0583	DNA-binding transcription factor activity
JV59_22120	COG1733	regulation of RNA biosynthetic process
JV59_22160	COG1733	regulation of RNA biosynthetic process
JV59_22180	COG4977	sequence-specific DNA binding
JV59_22180	COG1917	Cupin 2, conserved barrel domain protein
JV59_22185	COG4771	TonB-dependent receptor
JV59_22190	COG2814	Major facilitator Superfamily
JV59_22215	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JV59_22220	COG1169	isochorismate synthase
JV59_22225	COG1021	2,3-dihydroxybenzoate-AMP ligase
JV59_22230	COG1132	(ABC) transporter
JV59_22235	COG1132	(ABC) transporter
JV59_22260	COG0024	Methionine aminopeptidase
JV59_22270	COG0561	phosphatase activity
JV59_22275	COG1482	cell wall glycoprotein biosynthetic process
JV59_22280	COG0383	alpha-mannosidase activity
JV59_22285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_22285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_22285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_22290	COG2188	Transcriptional regulator
JV59_22340	COG0300	oxidoreductase activity
JV59_22350	COG0583	DNA-binding transcription factor activity
JV59_22360	COG2249	NAD(P)H dehydrogenase (quinone) activity
JV59_22410	COG1619	proteins homologs of microcin C7 resistance protein MccF
JV59_22425	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JV59_22430	COG1640	4-alpha-glucanotransferase
JV59_22435	COG0058	SHG alpha-glucan phosphorylase activity
JV59_22440	COG2909	trisaccharide binding
JV59_22485	COG2207	Transcriptional regulator
JV59_22490	COG1335	isochorismatase
JV59_22495	COG1404	Belongs to the peptidase S8 family
JV59_22500	COG0402	S-adenosylhomocysteine deaminase activity
JV59_22530	COG3795	YCII-related domain
JV59_22555	COG2186	Transcriptional regulator
JV59_22565	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JV59_22575	COG0402	S-adenosylhomocysteine deaminase activity
JV59_22585	COG2205	protein histidine kinase activity
JV59_22585	COG0784	Response regulator, receiver
JV59_22585	COG5002	protein histidine kinase activity
JV59_22595	COG1522	sequence-specific DNA binding
JV59_22605	COG0840	transmembrane signaling receptor activity
JV59_22620	COG4266	Belongs to the allantoicase family
JV59_22640	COG2252	PERMEase
JV59_22655	COG0596	Alpha beta hydrolase
JV59_22660	COG3214	Protein conserved in bacteria
JV59_22690	COG0583	DNA-binding transcription factor activity
JV59_22715	COG3179	chitinase
JV59_22740	COG0109	protoheme IX farnesyltransferase activity
JV59_22745	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JV59_22750	COG1845	cytochrome c oxidase, subunit III
JV59_22755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JV59_22760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JV59_22770	COG2706	6-phosphogluconolactonase activity
JV59_22780	COG0800	Aldolase
JV59_22785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JV59_22815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JV59_22820	COG0840	transmembrane signaling receptor activity
JV59_22855	COG0830	nickel cation binding
JV59_22865	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
JV59_22870	COG0804	urea catabolic process
JV59_22875	COG0832	Belongs to the urease beta subunit family
JV59_22880	COG0831	urea catabolic process
JV59_22905	COG0559	Belongs to the binding-protein-dependent transport system permease family
JV59_22920	COG2207	Transcriptional regulator
JV59_22920	COG1917	Cupin 2, conserved barrel domain protein
JV59_22950	COG2084	Dehydrogenase
JV59_22955	COG3622	Belongs to the hyi family
JV59_22960	COG3960	tartronate-semialdehyde synthase activity
JV59_22965	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JV59_22980	COG1288	antiporter activity
JV59_23010	COG1846	Transcriptional regulator
JV59_23015	COG0697	spore germination
JV59_23020	COG3300	MHYT domain
JV59_23020	COG5001	Diguanylate cyclase
JV59_23035	COG1051	belongs to the nudix hydrolase family
JV59_23040	COG0583	DNA-binding transcription factor activity
JV59_23060	COG1733	regulation of RNA biosynthetic process
JV59_23065	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_23075	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_23110	COG0444	Belongs to the ABC transporter superfamily
JV59_23115	COG4608	Belongs to the ABC transporter superfamily
JV59_23145	COG1444	tRNA N-acetyltransferase activity
JV59_23150	COG0840	transmembrane signaling receptor activity
JV59_23160	COG0745	RESPONSE REGULATOR receiver
JV59_23175	COG0835	chemotaxis
JV59_23180	COG0840	transmembrane signaling receptor activity
JV59_23185	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JV59_23210	COG0745	RESPONSE REGULATOR receiver
JV59_23210	COG3706	GGDEF domain
JV59_23230	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JV59_23290	COG0583	DNA-binding transcription factor activity
JV59_23315	COG0546	phosphoglycolate phosphatase activity
JV59_23320	COG3842	ATPase activity
JV59_23325	COG0589	response to stress
JV59_23335	COG2723	6-phospho-beta-galactosidase activity
JV59_23340	COG0768	penicillin binding
JV59_23345	COG0840	transmembrane signaling receptor activity
JV59_23365	COG0583	DNA-binding transcription factor activity
JV59_23385	COG0656	L-ascorbic acid biosynthetic process
JV59_23390	COG0351	phosphomethylpyrimidine kinase
JV59_23395	COG1116	anion transmembrane transporter activity
JV59_23400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JV59_23405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JV59_23410	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JV59_23430	COG2207	Transcriptional regulator
JV59_23430	COG3708	Transcriptional regulator
JV59_23440	COG0671	phosphoesterase, PA-phosphatase related
JV59_23450	COG0438	transferase activity, transferring glycosyl groups
JV59_23460	COG1940	carbohydrate kinase activity
JV59_23475	COG1175	transmembrane transport
JV59_23485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JV59_23505	COG0583	DNA-binding transcription factor activity
JV59_23535	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JV59_23535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JV59_23545	COG0251	oxidation-reduction process
JV59_23550	COG0697	spore germination
JV59_23565	COG1595	DNA-templated transcription, initiation
JV59_23605	COG0471	metal ion transport
JV59_23610	COG4191	Histidine kinase
JV59_23610	COG0745	RESPONSE REGULATOR receiver
JV59_23610	COG2205	protein histidine kinase activity
JV59_23615	COG0745	RESPONSE REGULATOR receiver
JV59_23640	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JV59_23650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_23655	COG0745	RESPONSE REGULATOR receiver
JV59_23660	COG3437	response regulator, receiver
JV59_23660	COG4999	Histidine kinase
JV59_23660	COG3850	Histidine kinase
JV59_23660	COG2205	protein histidine kinase activity
JV59_23680	COG0745	RESPONSE REGULATOR receiver
JV59_23690	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JV59_23705	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JV59_23710	COG3366	ferrous iron transmembrane transporter activity
JV59_23715	COG0700	Nucleoside recognition
JV59_23725	COG2207	Transcriptional regulator
JV59_23735	COG1404	Belongs to the peptidase S8 family
JV59_23740	COG2200	EAL domain
JV59_23915	COG0583	DNA-binding transcription factor activity
JV59_23920	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_23935	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JV59_23945	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JV59_23950	COG0584	glycerophosphoryl diester phosphodiesterase
JV59_23975	COG0583	DNA-binding transcription factor activity
JV59_23980	COG0393	Putative heavy-metal-binding
JV59_23985	COG1671	Belongs to the UPF0178 family
JV59_24000	COG1999	signal sequence binding
JV59_24010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JV59_24015	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JV59_24020	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JV59_24025	COG3033	Beta-eliminating lyase
JV59_24055	COG0259	pyridoxamine-phosphate oxidase activity
JV59_24065	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JV59_24110	COG1132	(ABC) transporter
JV59_24120	COG0583	DNA-binding transcription factor activity
JV59_24135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JV59_24145	COG0786	glutamate:sodium symporter activity
JV59_24150	COG1566	PFAM secretion protein HlyD family protein
JV59_24180	COG0813	purine-nucleoside phosphorylase activity
JV59_24185	COG3272	Protein of unknown function (DUF1722)
JV59_24190	COG0789	Transcriptional regulator
JV59_24195	COG0415	Belongs to the DNA photolyase family
JV59_24200	COG1376	ErfK ybiS ycfS ynhG family protein
JV59_24200	COG1388	LysM domain
JV59_24210	COG0513	Belongs to the DEAD box helicase family
JV59_24215	COG3291	Pkd domain containing protein
JV59_24220	COG3568	Endonuclease Exonuclease Phosphatase
JV59_24260	COG0604	alcohol dehydrogenase
JV59_24270	COG0702	epimerase
JV59_24290	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
JV59_24305	COG0583	DNA-binding transcription factor activity
JV59_24310	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_24415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JV59_24425	COG2084	Dehydrogenase
JV59_24510	COG0494	nUDIX hydrolase
JV59_24560	COG1742	UPF0060 membrane protein
JV59_24570	COG0251	oxidation-reduction process
JV59_24600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JV59_24685	COG1074	ATP-dependent DNA helicase activity
JV59_24700	COG1335	isochorismatase
JV59_24705	COG1741	Belongs to the pirin family
JV59_24710	COG0583	DNA-binding transcription factor activity
JV59_24740	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_24750	COG2274	protein secretion by the type I secretion system
JV59_24760	COG2274	protein secretion by the type I secretion system
JV59_24770	COG0583	DNA-binding transcription factor activity
JV59_24805	COG3706	GGDEF domain
JV59_24815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JV59_24820	COG4139	cobalamin transport
JV59_24855	COG0693	protein deglycase activity
JV59_24910	COG1335	isochorismatase
JV59_24915	COG2169	Transcriptional regulator
JV59_24960	COG2267	carboxylic ester hydrolase activity
JV59_24985	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JV59_24990	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JV59_25005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JV59_25035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JV59_25085	COG2003	Belongs to the UPF0758 family
JV59_25195	COG0305	Participates in initiation and elongation during chromosome replication
JV59_25200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JV59_25230	COG0215	cysteine-tRNA ligase activity
JV59_25240	COG1045	serine acetyltransferase
JV59_25245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JV59_25290	COG2814	Major facilitator Superfamily
JV59_25335	COG1401	restriction endodeoxyribonuclease activity
JV59_25425	COG1609	Transcriptional regulator
JV59_25435	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JV59_25445	COG1280	lysine exporter protein (LysE YggA)
JV59_25450	COG0735	belongs to the Fur family
JV59_25555	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JV59_25555	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JV59_25560	COG0840	transmembrane signaling receptor activity
JV59_25565	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JV59_25585	COG1181	Belongs to the D-alanine--D-alanine ligase family
JV59_25590	COG4191	Histidine kinase
JV59_25655	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JV59_25675	COG1192	Involved in chromosome partitioning
JV59_25685	COG2814	Major facilitator Superfamily
JV59_25700	COG3033	Beta-eliminating lyase
JV59_25730	COG0745	RESPONSE REGULATOR receiver
JV59_25740	COG4191	Histidine kinase
JV59_25745	COG3300	MHYT domain
JV59_25745	COG5001	Diguanylate cyclase
JV59_25810	COG0814	amino acid
JV59_25830	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_25835	COG0583	DNA-binding transcription factor activity
JV59_25845	COG3527	Alpha-acetolactate decarboxylase
JV59_25855	COG0745	RESPONSE REGULATOR receiver
JV59_25860	COG2205	protein histidine kinase activity
JV59_25975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JV59_25985	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JV59_25990	COG0250	Participates in transcription elongation, termination and antitermination
JV59_26005	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JV59_26015	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
JV59_26035	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JV59_26065	COG0802	atpase or kinase
JV59_26075	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
JV59_26085	COG0545	Peptidyl-prolyl cis-trans isomerase
JV59_26090	COG2964	Protein conserved in bacteria
JV59_26100	COG2923	Belongs to the DsrF TusC family
JV59_26115	COG0049	tRNA binding
JV59_26120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JV59_26125	COG2906	2 iron, 2 sulfur cluster binding
JV59_26155	COG0305	Participates in initiation and elongation during chromosome replication
JV59_26160	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JV59_26165	COG0432	Pfam Uncharacterised protein family UPF0047
JV59_26185	COG1136	(ABC) transporter
JV59_26200	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
JV59_26210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JV59_26215	COG2105	PFAM AIG2 family protein
JV59_26235	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JV59_26240	COG0163	prenyltransferase activity
JV59_26245	COG4143	(ABC) transporter
JV59_26250	COG1178	ABC-type Fe3 transport system permease component
JV59_26255	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
JV59_26260	COG3028	Belongs to the UPF0307 family
JV59_26265	COG0312	modulator of DNA gyrase
JV59_26270	COG0527	aspartate kinase activity
JV59_26275	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JV59_26300	COG0629	single-stranded DNA binding
JV59_26325	COG3409	Peptidoglycan-binding domain 1 protein
JV59_26325	COG3267	Type II secretory pathway component ExeA
JV59_26335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JV59_26400	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
JV59_26490	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JV59_26495	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JV59_26500	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JV59_26510	COG3610	response to peptide
JV59_26545	COG1610	YqeY-like protein
JV59_26550	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JV59_26555	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JV59_26560	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JV59_26565	COG0228	four-way junction DNA binding
JV59_26575	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JV59_26580	COG4969	Belongs to the N-Me-Phe pilin family
JV59_26585	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JV59_26610	COG1534	Rna-binding protein
JV59_26645	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JV59_26650	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JV59_26655	COG0494	nUDIX hydrolase
JV59_26670	COG0730	response to heat
JV59_26675	COG0583	DNA-binding transcription factor activity
JV59_26685	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JV59_26690	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JV59_26705	COG3022	response to hydroperoxide
JV59_26710	COG0084	hydrolase, TatD family'
JV59_26725	COG0813	purine-nucleoside phosphorylase activity
JV59_26735	COG0693	protein deglycase activity
JV59_26740	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JV59_26745	COG3248	Nucleoside-binding outer membrane protein
JV59_26755	COG1595	DNA-templated transcription, initiation
JV59_26765	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JV59_26775	COG0271	Belongs to the BolA IbaG family
JV59_26790	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JV59_26800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JV59_26810	COG0189	ligase activity
JV59_26815	COG0189	ligase activity
JV59_26815	COG4067	protein conserved in archaea
JV59_26820	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
JV59_26830	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JV59_26850	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JV59_26855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JV59_26865	COG0024	Methionine aminopeptidase
JV59_26870	COG0052	Belongs to the universal ribosomal protein uS2 family
JV59_26880	COG0528	UMP kinase activity
JV59_26885	COG0233	cytoplasmic translational termination
JV59_26890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JV59_26895	COG0575	Belongs to the CDS family
JV59_26900	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
JV59_26915	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JV59_26920	COG0825	malonyl-CoA metabolic process
JV59_26930	COG0347	Belongs to the P(II) protein family
JV59_26950	COG2226	methyltransferase
JV59_26960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JV59_26965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JV59_26970	COG0121	glutamine amidotransferase
JV59_26975	COG1720	tRNA m6t6A37 methyltransferase activity
JV59_26995	COG1464	Belongs to the NlpA lipoprotein family
JV59_27000	COG2011	ABC-type metal ion transport system permease component
JV59_27005	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JV59_27015	COG1609	Transcriptional regulator
JV59_27035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_27060	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JV59_27075	COG1686	Belongs to the peptidase S11 family
JV59_27080	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JV59_27085	COG0772	Belongs to the SEDS family
JV59_27090	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JV59_27095	COG0799	negative regulation of ribosome biogenesis
JV59_27100	COG1466	dna polymerase III delta subunit
JV59_27105	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
JV59_27110	COG2888	peptidyl-tyrosine sulfation
JV59_27115	COG4535	Mg2 and Co2 transporter CorC
JV59_27120	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JV59_27125	COG1702	phosphate starvation-inducible protein PhoH
JV59_27130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JV59_27135	COG2190	(PTS) system
JV59_27140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_27145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JV59_27150	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
JV59_27155	COG3115	cell septum assembly
JV59_27175	COG0330	HflC and HflK could
JV59_27180	COG3118	belongs to the thioredoxin family
JV59_27185	COG0300	oxidoreductase activity
JV59_27190	COG1090	epimerase
JV59_27215	COG0622	Phosphoesterase
JV59_27235	COG3710	Transcriptional regulator
JV59_27245	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JV59_27300	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JV59_27340	COG2747	anti-sigma28 factor FlgM
JV59_27350	COG0835	chemotaxis
JV59_27350	COG0784	Response regulator, receiver
JV59_27355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JV59_27360	COG1815	bacterial-type flagellum-dependent cell motility
JV59_27365	COG1558	bacterial-type flagellum-dependent cell motility
JV59_27370	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JV59_27375	COG1749	Flagellar hook protein flgE
JV59_27380	COG4787	bacterial-type flagellum-dependent cell motility
JV59_27385	COG4786	Flagellar basal body rod
JV59_27390	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JV59_27395	COG1706	bacterial-type flagellum-dependent cell motility
JV59_27400	COG1705	Flagellar rod assembly protein muramidase FlgJ
JV59_27400	COG3951	Flagellar rod assembly protein muramidase FlgJ
JV59_27405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JV59_27410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JV59_27415	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JV59_27465	COG0012	GTP binding
JV59_27475	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JV59_27495	COG2890	protein-(glutamine-N5) methyltransferase activity
JV59_27515	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JV59_27540	COG1393	Belongs to the ArsC family
JV59_27545	COG4783	chaperone-mediated protein folding
JV59_27565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JV59_27570	COG2716	regulation of RNA biosynthetic process
JV59_27575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JV59_27585	COG2056	Na+-H+ antiporter family
JV59_27605	COG0346	lactoylglutathione lyase activity
JV59_27610	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JV59_27620	COG4658	electron transport chain
JV59_27625	COG4656	Part of a membrane complex involved in electron transport
JV59_27635	COG4657	Part of a membrane complex involved in electron transport
JV59_27640	COG0741	lytic transglycosylase activity
JV59_27640	COG1388	LysM domain
JV59_27660	COG1815	bacterial-type flagellum-dependent cell motility
JV59_27665	COG1558	bacterial-type flagellum-dependent cell motility
JV59_27670	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JV59_27675	COG1749	Flagellar hook protein flgE
JV59_27680	COG4787	bacterial-type flagellum-dependent cell motility
JV59_27685	COG4786	Flagellar basal body rod
JV59_27690	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JV59_27695	COG1706	bacterial-type flagellum-dependent cell motility
JV59_27725	COG1360	Flagellar Motor Protein
JV59_27730	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JV59_27735	COG1191	sigma factor activity
JV59_27740	COG1580	Controls the rotational direction of flagella during chemotaxis
JV59_27755	COG1516	flagellar protein fliS
JV59_27760	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JV59_27765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JV59_27780	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JV59_27790	COG1987	bacterial-type flagellum assembly
JV59_27810	COG2885	chlorophyll binding
JV59_27815	COG2204	response regulator
JV59_27830	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JV59_27855	COG0739	heme binding
JV59_27865	COG0556	nucleotide-excision repair
JV59_27875	COG2198	Histidine kinase
JV59_27880	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JV59_27885	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JV59_27890	COG0521	Mo-molybdopterin cofactor biosynthetic process
JV59_27895	COG0315	cyclic pyranopterin monophosphate synthase activity
JV59_27900	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JV59_27905	COG0314	molybdopterin synthase activity
JV59_27910	COG3706	GGDEF domain
JV59_27920	COG0517	IMP dehydrogenase activity
JV59_27960	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JV59_27960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JV59_27965	COG0489	protein tyrosine kinase activity
JV59_27970	COG0572	uridine kinase
JV59_27975	COG2982	Protein involved in outer membrane biogenesis
JV59_27985	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
JV59_27995	COG0302	gtp cyclohydrolase
JV59_28000	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JV59_28005	COG0302	gtp cyclohydrolase
JV59_28005	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JV59_28010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JV59_28030	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JV59_28035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JV59_28045	COG1881	PFAM PEBP family protein
JV59_28055	COG0123	including yeast histone deacetylase and acetoin utilization protein
JV59_28085	COG3852	Histidine kinase
JV59_28120	COG3083	sulfuric ester hydrolase activity
JV59_28125	COG3082	Protein of unknown function (DUF1414)
JV59_28150	COG1757	Na H antiporter
JV59_28155	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JV59_28160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JV59_28165	COG2095	MarC family integral membrane protein
JV59_28170	COG1012	belongs to the aldehyde dehydrogenase family
JV59_28170	COG1454	alcohol dehydrogenase
JV59_28185	COG0850	regulation of cytokinetic process
JV59_28190	COG3100	YcgL domain-containing protein
JV59_28195	COG2951	lytic endotransglycosylase activity
JV59_28200	COG0583	DNA-binding transcription factor activity
JV59_28205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JV59_28215	COG2983	Belongs to the UPF0260 family
JV59_28220	COG0668	transmembrane transport
JV59_28240	COG1785	Belongs to the alkaline phosphatase family
JV59_28255	COG2226	methyltransferase
JV59_28285	COG3139	Protein of unknown function (DUF1315)
JV59_28290	COG3012	SEC-C Motif Domain Protein
JV59_28295	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JV59_28305	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JV59_28310	COG0215	cysteine-tRNA ligase activity
JV59_28315	COG1435	thymidine kinase activity
JV59_28320	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JV59_28325	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
JV59_28350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JV59_28355	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JV59_28380	COG3070	regulator of competence-specific genes
JV59_28395	COG0745	RESPONSE REGULATOR receiver
JV59_28400	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JV59_28405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JV59_28415	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
JV59_28450	COG0189	ligase activity
JV59_28450	COG4067	protein conserved in archaea
JV59_28465	COG1801	Protein of unknown function DUF72
JV59_28475	COG1187	pseudouridine synthase activity
JV59_28485	COG1278	Cold shock
JV59_28490	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JV59_28495	COG0542	response to heat
JV59_28520	COG2116	formate transmembrane transporter activity
JV59_28525	COG0390	transport system, permease component
JV59_28530	COG4459	periplasmic nitrate reductase
JV59_28535	COG3005	denitrification pathway
JV59_28540	COG0243	molybdopterin cofactor binding
JV59_28555	COG4221	oxidoreductase activity
JV59_28575	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JV59_28580	COG0840	transmembrane signaling receptor activity
JV59_28585	COG0632	four-way junction helicase activity
JV59_28590	COG2255	four-way junction helicase activity
JV59_28595	COG1271	oxidase subunit
JV59_28600	COG1294	oxidase, subunit
JV59_28605	COG4890	Cyd operon protein YbgT
JV59_28615	COG0824	Thioesterase
JV59_28620	COG0811	peptide transport
JV59_28640	COG2885	chlorophyll binding
JV59_28645	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
JV59_28650	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JV59_28655	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JV59_28675	COG0784	Response regulator, receiver
JV59_28675	COG5002	protein histidine kinase activity
JV59_28695	COG1902	pentaerythritol trinitrate reductase activity
JV59_28700	COG1881	PFAM PEBP family protein
JV59_28705	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JV59_28720	COG1940	carbohydrate kinase activity
JV59_28735	COG3850	Histidine kinase
JV59_28735	COG5002	protein histidine kinase activity
JV59_28740	COG0745	RESPONSE REGULATOR receiver
JV59_28745	COG0463	Glycosyl transferase, family 2
JV59_28750	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JV59_28770	COG1960	acyl-CoA dehydrogenase activity
JV59_28775	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JV59_28780	COG0708	Exodeoxyribonuclease III
JV59_28785	COG0840	transmembrane signaling receptor activity
JV59_28805	COG0730	response to heat
JV59_28810	COG1199	ATP-dependent helicase activity
JV59_28820	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JV59_28830	COG0156	8-amino-7-oxononanoate synthase activity
JV59_28835	COG2226	methyltransferase
JV59_28835	COG1073	alpha beta
JV59_28840	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JV59_28865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JV59_28875	COG2268	Band 7 protein
JV59_28885	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JV59_28895	COG0482	sulfurtransferase activity
JV59_28905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JV59_28915	COG1757	Na H antiporter
JV59_28925	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JV59_28935	COG0131	Imidazoleglycerol-phosphate dehydratase
JV59_28935	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JV59_28940	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JV59_28950	COG0107	imidazoleglycerol-phosphate synthase activity
JV59_28955	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JV59_28955	COG0140	phosphoribosyl-ATP diphosphatase activity
JV59_28960	COG0217	transcriptional regulatory protein
JV59_28970	COG1227	inorganic diphosphatase activity
JV59_28985	COG4172	Belongs to the ABC transporter superfamily
JV59_28995	COG4171	peptide transport system, permease
JV59_29000	COG4168	peptide transport system, permease
JV59_29010	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JV59_29015	COG1842	Phage shock protein A
JV59_29025	COG1983	PspC domain protein
JV59_29045	COG2818	Glycosylase
JV59_29050	COG5380	lipid catabolic process
JV59_29055	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JV59_29060	COG0626	cystathionine gamma-synthase activity
JV59_29070	COG0733	neurotransmitter:sodium symporter activity
JV59_29075	COG0564	pseudouridine synthase activity
JV59_29080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JV59_29085	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JV59_29090	COG4136	ATPase activity
JV59_29095	COG4135	transport system, permease component
JV59_29100	COG4134	Bacterial extracellular solute-binding protein
JV59_29110	COG3313	Fe-S protein
JV59_29125	COG2350	Protein conserved in bacteria
JV59_29130	COG1607	acyl-coa hydrolase
JV59_29165	COG3099	Belongs to the UPF0263 family
JV59_29170	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JV59_29200	COG2197	response regulator
JV59_29205	COG0322	excinuclease ABC activity
JV59_29235	COG1902	pentaerythritol trinitrate reductase activity
JV59_29245	COG2133	pyrroloquinoline quinone binding
JV59_29270	COG0072	phenylalanine-tRNA ligase activity
JV59_29270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JV59_29320	COG1741	Belongs to the pirin family
JV59_29325	COG1335	isochorismatase
JV59_29335	COG1263	PTS System
JV59_29335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JV59_29350	COG1621	beta-fructofuranosidase activity
JV59_29370	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JV59_29375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JV59_29395	COG0583	DNA-binding transcription factor activity
JV59_29405	COG0277	FAD linked oxidase domain protein
JV59_29415	COG4211	Belongs to the binding-protein-dependent transport system permease family
JV59_29420	COG1129	ABC transporter
JV59_29430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JV59_29435	COG3962	Belongs to the TPP enzyme family
JV59_29505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JV59_29530	COG0583	DNA-binding transcription factor activity
JV59_29540	COG2995	paraquat-inducible protein a
JV59_29545	COG3008	intermembrane lipid transfer
JV59_29545	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JV59_29565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JV59_29570	COG0183	Belongs to the thiolase family
JV59_29585	COG0583	DNA-binding transcription factor activity
JV59_29590	COG0477	Major facilitator Superfamily
JV59_29590	COG2814	Major facilitator Superfamily
JV59_29600	COG3962	Belongs to the TPP enzyme family
JV59_29605	COG0673	inositol 2-dehydrogenase activity
JV59_29635	COG0673	inositol 2-dehydrogenase activity
JV59_29645	COG1216	Glycosyl transferase, family 2
JV59_29650	COG2223	nitrite transmembrane transporter activity
JV59_29660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JV59_29665	COG3437	response regulator, receiver
JV59_29675	COG0784	Response regulator, receiver
JV59_29675	COG2205	protein histidine kinase activity
JV59_29685	COG1858	cytochrome C peroxidase
JV59_29705	COG0745	RESPONSE REGULATOR receiver
JV59_29710	COG0642	Histidine kinase
JV59_29720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JV59_29745	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JV59_29795	COG0583	DNA-binding transcription factor activity
JV59_29840	COG0583	DNA-binding transcription factor activity
JV59_29845	COG0352	thiamine-phosphate diphosphorylase activity
JV59_29850	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JV59_29860	COG1115	amino acid carrier protein
JV59_29890	COG3300	MHYT domain
JV59_29890	COG5001	Diguanylate cyclase
JV59_29945	COG0778	Nitroreductase
JV59_29950	COG4580	involved in the transport of maltose and maltodextrins
JV59_29970	COG0519	Catalyzes the synthesis of GMP from XMP
JV59_29975	COG0242	peptide deformylase activity
JV59_30020	COG0307	riboflavin synthase, alpha
JV59_30055	COG4221	oxidoreductase activity
JV59_30085	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JV59_30090	COG0583	DNA-binding transcription factor activity
JV59_30100	COG1621	beta-fructofuranosidase activity
JV59_30105	COG1263	PTS System
JV59_30105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JV59_30110	COG2188	Transcriptional regulator
JV59_30120	COG0463	Glycosyl transferase, family 2
JV59_30140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_30145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JV59_30170	COG2205	protein histidine kinase activity
JV59_30185	COG1061	Type III restriction enzyme res subunit
JV59_30195	COG2814	Major facilitator Superfamily
JV59_30205	COG0702	epimerase
JV59_30210	COG0534	Mate efflux family protein
JV59_30215	COG1136	(ABC) transporter
JV59_30260	COG0019	diaminopimelate decarboxylase activity
JV59_30285	COG0633	Ferredoxin
JV59_30290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JV59_30300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JV59_30310	COG0840	transmembrane signaling receptor activity
JV59_30315	COG1328	CTP reductase activity
JV59_30320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JV59_30360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JV59_30365	COG0745	RESPONSE REGULATOR receiver
JV59_30370	COG2205	protein histidine kinase activity
JV59_30375	COG4774	siderophore transport
JV59_30385	COG0811	peptide transport
JV59_30390	COG0811	peptide transport
JV59_30395	COG0848	biopolymer transport protein
JV59_30415	COG3290	protein histidine kinase activity
JV59_30420	COG4565	transcriptional regulatory protein
JV59_30450	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JV59_30455	COG2146	nitrite reductase [NAD(P)H] activity
JV59_30460	COG2116	formate transmembrane transporter activity
JV59_30480	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JV59_30500	COG0583	DNA-binding transcription factor activity
JV59_30520	COG1475	DNA binding
JV59_30530	COG0814	amino acid
JV59_30535	COG0745	RESPONSE REGULATOR receiver
JV59_30545	COG3713	MltA-interacting MipA family protein
JV59_30560	COG2814	Major facilitator Superfamily
JV59_30565	COG0583	DNA-binding transcription factor activity
JV59_30580	COG3835	regulator
JV59_30585	COG2977	Belongs to the P-Pant transferase superfamily
JV59_30590	COG1120	ATPase activity
JV59_30595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JV59_30605	COG4615	Cyclic peptide transporter
JV59_30620	COG4774	siderophore transport
JV59_30655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JV59_30700	COG2204	response regulator
JV59_30750	COG0307	riboflavin synthase, alpha
JV59_30770	COG0791	NLP P60 protein
JV59_30775	COG3290	protein histidine kinase activity
JV59_30775	COG0840	transmembrane signaling receptor activity
JV59_30820	COG0303	'Molybdopterin
JV59_30825	COG0746	molybdenum cofactor guanylyltransferase activity
JV59_30830	COG3842	ATPase activity
JV59_30835	COG4662	Binding-protein-dependent transport system inner membrane component
JV59_30850	COG3852	Histidine kinase
JV59_30865	COG1595	DNA-templated transcription, initiation
JV59_30875	COG0488	(ABC) transporter
JV59_30890	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_30900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JV59_30915	COG0069	glutamate synthase activity
JV59_30935	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JV59_30940	COG0583	DNA-binding transcription factor activity
JV59_30950	COG0583	DNA-binding transcription factor activity
JV59_30975	COG3038	cytochrome b561
JV59_30980	COG0840	transmembrane signaling receptor activity
JV59_30985	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JV59_31015	COG0243	molybdopterin cofactor binding
JV59_31015	COG3383	formate dehydrogenase (NAD+) activity
JV59_31020	COG0437	4 iron, 4 sulfur cluster binding
JV59_31035	COG0004	ammonium transporteR
JV59_31040	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JV59_31045	COG2199	diguanylate cyclase activity
JV59_31050	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JV59_31055	COG1177	transmembrane transport
JV59_31060	COG1176	ABC-type spermidine putrescine transport system, permease component I
JV59_31065	COG3842	ATPase activity
JV59_31090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JV59_31105	COG2217	Heavy metal translocating P-type atpase
JV59_31115	COG2010	Cytochrome c
JV59_31130	COG3278	Belongs to the heme-copper respiratory oxidase family
JV59_31165	COG2197	response regulator
JV59_31255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JV59_31265	COG3424	synthase
JV59_31400	COG0840	transmembrane signaling receptor activity
JV59_31405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JV59_31625	COG1067	ATP-dependent peptidase activity
JV59_31630	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JV59_31645	COG0488	(ABC) transporter
JV59_31665	COG0167	dihydroorotate dehydrogenase activity
JV59_31680	COG0308	aminopeptidase N
JV59_31695	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
JV59_31700	COG1956	GAF domain-containing protein
JV59_31705	COG1132	(ABC) transporter
JV59_31710	COG2995	paraquat-inducible protein a
JV59_31715	COG3008	intermembrane lipid transfer
JV59_31745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JV59_31750	COG1666	GTP binding
JV59_31760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JV59_31765	COG4597	amino acid ABC transporter
JV59_31770	COG0765	amino acid transport
JV59_31775	COG1126	abc transporter atp-binding protein
JV59_31780	COG0670	Belongs to the BI1 family
JV59_31785	COG2920	part of a sulfur-relay system
JV59_31790	COG1254	Belongs to the acylphosphatase family
JV59_31795	COG0840	transmembrane signaling receptor activity
JV59_31800	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JV59_31830	COG0561	phosphatase activity
JV59_31850	COG2828	Protein conserved in bacteria
JV59_31860	COG0372	Belongs to the citrate synthase family
JV59_31865	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JV59_31880	COG3501	Rhs element vgr protein
JV59_31980	COG0515	serine threonine protein kinase
JV59_31985	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JV59_32010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_32025	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JV59_32045	COG0508	dehydrogenase complex catalyzes the overall conversion of
JV59_32045	COG0596	Alpha beta hydrolase
JV59_32050	COG3063	Type IV pilus biogenesis stability protein PilW
JV59_32065	COG1451	nucleotide metabolic process
JV59_32085	COG1119	ATPase activity
JV59_32105	COG3706	GGDEF domain
JV59_32125	COG4139	cobalamin transport
JV59_32140	COG0406	alpha-ribazole phosphatase activity
JV59_32150	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JV59_32160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JV59_32165	COG0702	epimerase
JV59_32295	COG0740	serine-type endopeptidase activity
JV59_32420	COG0582	viral genome integration into host DNA
JV59_32425	COG2925	Exonuclease
JV59_32435	COG1346	cytolysis
JV59_32475	COG0500	methyltransferase
JV59_32495	COG4326	sporulation control protein
JV59_32500	COG2188	Transcriptional regulator
JV59_32505	COG1228	amidohydrolase
JV59_32510	COG0010	Belongs to the arginase family
JV59_32520	COG2986	histidine ammonia-lyase
JV59_32555	COG0625	glutathione transferase activity
JV59_32565	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JV59_32575	COG2195	Cleaves the N-terminal amino acid of tripeptides
JV59_32590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JV59_32595	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JV59_32610	COG0456	acetyltransferase
JV59_32640	COG0454	-acetyltransferase
JV59_32695	COG3122	Protein conserved in bacteria
JV59_32725	COG0456	acetyltransferase
JV59_32740	COG2824	Alkylphosphonate utilization operon protein PhnA
JV59_32750	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_32760	COG0730	response to heat
JV59_32770	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JV59_32785	COG4628	conserved protein (DUF2132)
JV59_32790	COG0546	phosphoglycolate phosphatase activity
JV59_32865	COG2962	Rard protein
JV59_32880	COG0783	Belongs to the Dps family
JV59_32885	COG4667	esterase of the alpha-beta hydrolase superfamily
JV59_32920	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JV59_32935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JV59_32940	COG3108	Peptidase M15
JV59_32945	COG2989	Protein conserved in bacteria
JV59_32970	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JV59_32980	COG3706	GGDEF domain
JV59_33000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JV59_33005	COG3283	Transcriptional regulator of aromatic amino acids metabolism
JV59_33015	COG3106	COG3106 Predicted ATPase
JV59_33030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JV59_33035	COG0784	Response regulator, receiver
JV59_33035	COG2205	protein histidine kinase activity
JV59_33045	COG0494	nUDIX hydrolase
JV59_33050	COG0814	amino acid
JV59_33055	COG1760	l-serine dehydratase
JV59_33065	COG0814	amino acid
JV59_33080	COG0017	Asparaginyl-tRNA synthetase
JV59_33090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JV59_33100	COG2770	Histidine kinase
JV59_33100	COG3437	response regulator, receiver
JV59_33105	COG1448	Aminotransferase
JV59_33120	COG1643	Atp-dependent helicase
JV59_33125	COG0281	malic enzyme
JV59_33135	COG2949	membrane
JV59_33145	COG0612	Peptidase, M16
JV59_33160	COG2175	clavaminate synthase activity
JV59_33175	COG0492	ferredoxin-NADP+ reductase activity
JV59_33180	COG4988	ABC transporter
JV59_33185	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JV59_33190	COG2814	Major facilitator Superfamily
JV59_33200	COG0384	phenazine biosynthesis protein PhzF
JV59_33205	COG1187	pseudouridine synthase activity
JV59_33220	COG0613	PHP domain protein
JV59_33230	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JV59_33235	COG0512	Glutamine amidotransferase of anthranilate synthase
JV59_33240	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JV59_33245	COG0134	indole-3-glycerol-phosphate synthase activity
JV59_33245	COG0135	phosphoribosylanthranilate isomerase activity
JV59_33250	COG0133	tryptophan synthase activity
JV59_33255	COG0159	tryptophan synthase activity
JV59_33260	COG1301	dicarboxylic acid transport
JV59_33390	COG1643	Atp-dependent helicase
JV59_33435	COG0443	Heat shock 70 kDa protein
JV59_33445	COG1858	cytochrome C peroxidase
JV59_33490	COG3152	Membrane
JV59_33505	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JV59_33510	COG0840	transmembrane signaling receptor activity
JV59_33530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JV59_33535	COG0673	inositol 2-dehydrogenase activity
JV59_33545	COG0583	DNA-binding transcription factor activity
JV59_33555	COG1846	Transcriptional regulator
JV59_33560	COG1764	response to oxidative stress
JV59_33565	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JV59_33590	COG1032	radical SAM domain protein
JV59_33600	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JV59_33610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JV59_33610	COG4191	Histidine kinase
JV59_33625	COG3070	regulator of competence-specific genes
JV59_33635	COG2431	L-lysine efflux transmembrane transporter activity
JV59_33645	COG0076	glutamate decarboxylase activity
JV59_33650	COG1737	Transcriptional regulator
JV59_33655	COG1454	alcohol dehydrogenase
JV59_33655	COG1012	belongs to the aldehyde dehydrogenase family
JV59_33685	COG3646	Phage regulatory protein
JV59_33740	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JV59_33755	COG4215	(ABC) transporter
JV59_33765	COG1882	Formate acetyltransferase
JV59_33780	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JV59_33790	COG3713	MltA-interacting MipA family protein
JV59_33795	COG2766	serine protein kinase
JV59_33800	COG2718	Belongs to the UPF0229 family
JV59_33805	COG2719	SpoVR family
JV59_33810	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JV59_33825	COG1132	(ABC) transporter
JV59_33830	COG2333	competence protein COMEC
JV59_33830	COG0658	competence protein
JV59_33840	COG4591	ABC-type transport system involved in lipoprotein release permease component
JV59_33845	COG1136	(ABC) transporter
JV59_33850	COG4591	ABC-type transport system involved in lipoprotein release permease component
JV59_33860	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JV59_33880	COG1252	NADH dehydrogenase
JV59_33910	COG0537	adenosine 5'-monophosphoramidase activity
JV59_33925	COG2186	Transcriptional regulator
JV59_33940	COG1674	ftsk spoiiie
JV59_33950	COG0686	Belongs to the AlaDH PNT family
JV59_33955	COG3092	negative regulation of chromosome organization
JV59_33965	COG0857	belongs to the CobB CobQ family
JV59_33965	COG0280	phosphate acetyltransferase
JV59_33970	COG3706	GGDEF domain
JV59_33975	COG0435	Glutathione S-transferase
JV59_33985	COG0444	Belongs to the ABC transporter superfamily
JV59_33990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JV59_33995	COG0601	transmembrane transport
JV59_34015	COG3706	GGDEF domain
JV59_34030	COG0840	transmembrane signaling receptor activity
JV59_34040	COG1404	Belongs to the peptidase S8 family
JV59_34045	COG0840	transmembrane signaling receptor activity
JV59_34055	COG0330	HflC and HflK could
JV59_34075	COG1136	(ABC) transporter
JV59_34075	COG0577	efflux transmembrane transporter activity
JV59_34080	COG1136	(ABC) transporter
JV59_34080	COG0577	efflux transmembrane transporter activity
JV59_34085	COG0577	efflux transmembrane transporter activity
JV59_34095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_34105	COG3227	Zinc metalloprotease (Elastase)
JV59_34115	COG1770	oligopeptidase
JV59_34120	COG3397	chitin binding
JV59_34135	COG1215	transferase activity, transferring glycosyl groups
JV59_34140	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JV59_34145	COG3876	Protein conserved in bacteria
JV59_34150	COG1472	Belongs to the glycosyl hydrolase 3 family
JV59_34170	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JV59_34175	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JV59_34180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JV59_34195	COG2855	membrane
JV59_34215	COG0730	response to heat
JV59_34220	COG0280	phosphate acetyltransferase
JV59_34225	COG1414	Transcriptional regulator
JV59_34255	COG3706	GGDEF domain
JV59_34270	COG3126	Type III secretion system lipoprotein chaperone (YscW)
JV59_34275	COG1946	Acyl-CoA thioesterase
JV59_34290	COG1522	sequence-specific DNA binding
JV59_34315	COG0477	Major facilitator Superfamily
JV59_34320	COG2855	membrane
JV59_34330	COG1441	menaquinone biosynthetic process
JV59_34340	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JV59_34345	COG1169	isochorismate synthase
JV59_34350	COG0436	Aminotransferase
JV59_34355	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
JV59_34370	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JV59_34375	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JV59_34390	COG0513	Belongs to the DEAD box helicase family
JV59_34395	COG0616	signal peptide processing
JV59_34400	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_34415	COG0784	Response regulator, receiver
JV59_34415	COG0835	chemotaxis
JV59_34420	COG1940	carbohydrate kinase activity
JV59_34425	COG0469	pyruvate kinase activity
JV59_34430	COG4667	esterase of the alpha-beta hydrolase superfamily
JV59_34445	COG0733	neurotransmitter:sodium symporter activity
JV59_34455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JV59_34455	COG1263	PTS System
JV59_34460	COG0084	hydrolase, TatD family'
JV59_34465	COG0470	DNA polymerase III
JV59_34470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JV59_34475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JV59_34480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JV59_34505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JV59_34520	COG1399	metal-binding, possibly nucleic acid-binding protein
JV59_34525	COG0424	maF-like protein
JV59_34530	COG0564	pseudouridine synthase activity
JV59_34535	COG1530	ribonuclease E activity
JV59_34540	COG0659	secondary active sulfate transmembrane transporter activity
JV59_34550	COG0318	PFAM AMP-dependent synthetase and ligase
JV59_34555	COG2267	carboxylic ester hydrolase activity
JV59_34570	COG1214	PFAM Peptidase M22, glycoprotease
JV59_34575	COG1199	ATP-dependent helicase activity
JV59_34585	COG0788	formyltetrahydrofolate deformylase activity
JV59_34590	COG0446	pyridine nucleotide-disulphide oxidoreductase
JV59_34590	COG1902	pentaerythritol trinitrate reductase activity
JV59_34595	COG0616	signal peptide processing
JV59_34600	COG0252	asparaginase activity
JV59_34610	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JV59_34615	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JV59_34625	COG0653	protein targeting
JV59_34635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JV59_34640	COG3706	GGDEF domain
JV59_34650	COG4120	Belongs to the binding-protein-dependent transport system permease family
JV59_34680	COG0284	orotidine-5'-phosphate decarboxylase activity
JV59_34685	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JV59_34690	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
JV59_34700	COG0539	negative regulation of cytoplasmic translation
JV59_34710	COG1555	photosystem II stabilization
JV59_34715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JV59_34720	COG0776	regulation of translation
JV59_34725	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JV59_34750	COG2204	response regulator
JV59_34760	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JV59_34765	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JV59_34770	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JV59_34775	COG3842	ATPase activity
JV59_34785	COG1653	transport
JV59_34790	COG2205	protein histidine kinase activity
JV59_34795	COG0745	RESPONSE REGULATOR receiver
JV59_34820	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JV59_34825	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JV59_34835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JV59_34840	COG2832	Protein of unknown function (DUF454)
JV59_34850	COG0745	RESPONSE REGULATOR receiver
JV59_34855	COG0583	DNA-binding transcription factor activity
JV59_34860	COG0778	Nitroreductase
JV59_34870	COG0183	Belongs to the thiolase family
JV59_34885	COG2067	long-chain fatty acid transport protein
JV59_34890	COG2067	long-chain fatty acid transport protein
JV59_34895	COG2853	Lipoprotein
JV59_34905	COG3088	subunit of a heme lyase
JV59_34905	COG4235	cytochrome complex assembly
JV59_34910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JV59_34915	COG1138	Cytochrome C-type biogenesis protein
JV59_34925	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JV59_34930	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JV59_34935	COG4133	protoheme IX ABC transporter activity
JV59_34945	COG0835	chemotaxis
JV59_34955	COG1192	Involved in chromosome partitioning
JV59_34960	COG2201	protein-glutamate methylesterase activity
JV59_34965	COG0643	Histidine kinase
JV59_34965	COG2198	Histidine kinase
JV59_34970	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
JV59_34985	COG0455	bacterial-type flagellum organization
JV59_35000	COG2062	phosphohistidine phosphatase, SixA
JV59_35005	COG1025	Belongs to the peptidase M16 family
JV59_35010	COG3102	Protein conserved in bacteria
JV59_35015	COG0018	arginyl-trna synthetase
JV59_35030	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JV59_35035	COG1918	ferrous iron import across plasma membrane
JV59_35040	COG4977	sequence-specific DNA binding
JV59_35045	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
JV59_35050	COG1121	(ABC) transporter
JV59_35055	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JV59_35060	COG1286	toxin biosynthetic process
JV59_35065	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
JV59_35070	COG0285	dihydrofolate synthase activity
JV59_35080	COG0101	tRNA pseudouridine synthase activity
JV59_35090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JV59_35095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JV59_35100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JV59_35130	COG3101	peptidyl-lysine hydroxylation
JV59_35135	COG2860	membrane
JV59_35145	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JV59_35150	COG2890	protein-(glutamine-N5) methyltransferase activity
JV59_35165	COG1684	flagellar biosynthetic protein fliR
JV59_35170	COG1987	bacterial-type flagellum assembly
JV59_35220	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JV59_35230	COG1677	Flagellar hook-basal body complex protein FliE
JV59_35235	COG2204	response regulator
JV59_35240	COG4191	Histidine kinase
JV59_35245	COG2204	response regulator
JV59_35250	COG1516	flagellar protein fliS
JV59_35260	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JV59_35270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JV59_35285	COG2837	iron assimilation
JV59_35295	COG3088	subunit of a heme lyase
JV59_35295	COG4235	cytochrome complex assembly
JV59_35300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JV59_35305	COG1138	Cytochrome C-type biogenesis protein
JV59_35310	COG3301	Polysulphide reductase, NrfD
JV59_35315	COG0437	4 iron, 4 sulfur cluster binding
JV59_35320	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
JV59_35350	COG1393	Belongs to the ArsC family
JV59_35355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JV59_35365	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
JV59_35385	COG3706	GGDEF domain
JV59_35385	COG0745	RESPONSE REGULATOR receiver
JV59_35390	COG1611	Belongs to the LOG family
JV59_35420	COG0583	DNA-binding transcription factor activity
JV59_35425	COG0301	tRNA thio-modification
JV59_35425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JV59_35435	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JV59_35445	COG0142	geranyltranstransferase activity
JV59_35455	COG0564	pseudouridine synthase activity
JV59_35460	COG3098	single-species biofilm formation
JV59_35490	COG0508	dehydrogenase complex catalyzes the overall conversion of
JV59_35495	COG0567	Dehydrogenase, E1 component
JV59_35500	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JV59_35505	COG1053	succinate dehydrogenase
JV59_35510	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JV59_35515	COG2009	succinate dehydrogenase
JV59_35525	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JV59_35535	COG0033	Phosphoglucomutase
JV59_35540	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
JV59_35545	COG0596	Alpha beta hydrolase
JV59_35555	COG0716	FMN binding
JV59_35570	COG0167	dihydroorotate dehydrogenase activity
JV59_35585	COG2190	(PTS) system
JV59_35585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JV59_35585	COG1263	PTS System
JV59_35590	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JV59_35595	COG1846	Transcriptional regulator
JV59_35595	COG1940	carbohydrate kinase activity
JV59_35600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JV59_35600	COG4651	solute:proton antiporter activity
JV59_35605	COG0367	asparagine synthase
JV59_35610	COG3104	oligopeptide transport
JV59_35635	COG2840	Smr protein MutS2
JV59_35640	COG1187	pseudouridine synthase activity
JV59_35645	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JV59_35650	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JV59_35655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JV59_35680	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
JV59_35685	COG0590	tRNA wobble adenosine to inosine editing
JV59_35690	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JV59_35710	COG4970	Tfp pilus assembly protein FimT
JV59_35725	COG0443	Heat shock 70 kDa protein
JV59_35730	COG1301	dicarboxylic acid transport
JV59_35735	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JV59_35745	COG0497	DNA recombination
JV59_35750	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JV59_35760	COG2867	negative regulation of translational initiation
JV59_35775	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JV59_35815	COG0668	transmembrane transport
JV59_35820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JV59_35840	COG0204	Acyl-transferase
JV59_35845	COG0784	Response regulator, receiver
JV59_35845	COG0835	chemotaxis
JV59_35870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JV59_35875	COG1115	amino acid carrier protein
JV59_35880	COG1584	GPR1 FUN34 yaaH family protein
JV59_35895	COG0517	IMP dehydrogenase activity
JV59_35895	COG0516	GMP reductase activity
JV59_35910	COG2203	Gaf domain
JV59_35910	COG2199	diguanylate cyclase activity
JV59_35920	COG1160	GTP binding
JV59_35925	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JV59_35930	COG2976	Protein conserved in bacteria
JV59_35935	COG0124	histidyl-tRNA synthetase
JV59_35945	COG1426	Protein conserved in bacteria
JV59_35955	COG2166	iron-sulfur cluster assembly
JV59_35960	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JV59_35965	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
JV59_35985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JV59_35990	COG1074	ATP-dependent DNA helicase activity
JV59_35995	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JV59_36015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_36020	COG1309	transcriptional regulator
JV59_36025	COG3141	response to X-ray
JV59_36060	COG0704	Plays a role in the regulation of phosphate uptake
JV59_36065	COG0581	inorganic phosphate transmembrane transporter activity
JV59_36070	COG0573	inorganic phosphate transmembrane transporter activity
JV59_36075	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JV59_36080	COG0248	Ppx GppA phosphatase
JV59_36090	COG5002	protein histidine kinase activity
JV59_36095	COG0745	RESPONSE REGULATOR receiver
JV59_36110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JV59_36130	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JV59_36135	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JV59_36140	COG1862	Preprotein translocase
JV59_36150	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JV59_36155	COG0517	IMP dehydrogenase activity
JV59_36165	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JV59_36170	COG0583	DNA-binding transcription factor activity
JV59_36175	COG0450	alkyl hydroperoxide reductase
JV59_36180	COG2171	N-acyltransferase activity
JV59_36190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_36200	COG2207	Transcriptional regulator
JV59_36205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_36205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_36205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_36215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JV59_36225	COG2017	converts alpha-aldose to the beta-anomer
JV59_36235	COG1085	galactose-1-phosphate uridylyltransferase
JV59_36240	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JV59_36245	COG1609	Transcriptional regulator
JV59_36250	COG3250	beta-galactosidase activity
JV59_36255	COG2731	YhcH YjgK YiaL family protein
JV59_36260	COG0531	amino acid
JV59_36280	COG3408	Glycogen debranching enzyme
JV59_36280	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
JV59_36290	COG2211	Major facilitator Superfamily
JV59_36295	COG1486	melibiose metabolic process
JV59_36300	COG2169	Transcriptional regulator
JV59_36350	COG4964	Belongs to the GSP D family
JV59_36380	COG2169	Transcriptional regulator
JV59_36390	COG0583	DNA-binding transcription factor activity
JV59_36400	COG0583	DNA-binding transcription factor activity
JV59_36405	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JV59_36415	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JV59_36420	COG2975	iron-sulfur cluster assembly
JV59_36425	COG0633	Ferredoxin
JV59_36445	COG0822	iron-sulfur transferase activity
JV59_36455	COG1959	2 iron, 2 sulfur cluster binding
JV59_36465	COG0483	inositol monophosphate 1-phosphatase activity
JV59_36505	COG0542	response to heat
JV59_36515	COG0564	pseudouridine synthase activity
JV59_36520	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JV59_36525	COG0741	lytic transglycosylase activity
JV59_36530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JV59_36535	COG1605	Chorismate mutase
JV59_36535	COG0077	Prephenate dehydratase
JV59_36540	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JV59_36545	COG5001	Diguanylate cyclase
JV59_36550	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
JV59_36555	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
JV59_36560	COG0741	lytic transglycosylase activity
JV59_36565	COG0488	(ABC) transporter
JV59_36575	COG0739	heme binding
JV59_36580	COG0287	Prephenate dehydrogenase
JV59_36580	COG1605	Chorismate mutase
JV59_36590	COG3275	phosphorelay sensor kinase activity
JV59_36595	COG3279	Response regulator of the LytR AlgR family
JV59_36600	COG1472	Belongs to the glycosyl hydrolase 3 family
JV59_36605	COG1737	Transcriptional regulator
JV59_36615	COG2971	BadF BadG BcrA BcrD
JV59_36620	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JV59_36625	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JV59_36635	COG1966	Carbon starvation protein
JV59_36640	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JV59_36645	COG1047	Peptidyl-prolyl cis-trans
JV59_36660	COG0196	riboflavin kinase activity
JV59_36665	COG0728	peptidoglycan biosynthetic process
JV59_36670	COG0268	Binds directly to 16S ribosomal RNA
JV59_36675	COG0640	Transcriptional regulator
JV59_36680	COG0583	DNA-binding transcription factor activity
JV59_36690	COG1283	sodium-dependent phosphate transmembrane transporter activity
JV59_36695	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JV59_36705	COG0730	response to heat
JV59_36720	COG3066	DNA modification
JV59_36730	COG0667	Aldo Keto reductase
JV59_36740	COG2204	response regulator
JV59_36745	COG0534	Mate efflux family protein
JV59_36750	COG1846	Transcriptional regulator
JV59_36775	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JV59_36780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JV59_36785	COG2860	membrane
JV59_36790	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JV59_36820	COG0745	RESPONSE REGULATOR receiver
JV59_36830	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JV59_36840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JV59_36845	COG3025	triphosphatase activity
JV59_36850	COG1392	Phosphate transport regulator
JV59_36855	COG0306	phosphate transporter
JV59_36860	COG4991	sh3 domain protein
JV59_36870	COG3267	Type II secretory pathway component ExeA
JV59_36870	COG3409	Peptidoglycan-binding domain 1 protein
JV59_36875	COG0617	tRNA 3'-terminal CCA addition
JV59_36880	COG0148	phosphopyruvate hydratase activity
JV59_36885	COG0148	phosphopyruvate hydratase activity
JV59_36890	COG0148	phosphopyruvate hydratase activity
JV59_36895	COG0148	phosphopyruvate hydratase activity
JV59_36905	COG3956	TIGRFAM MazG family protein
JV59_36910	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JV59_36915	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JV59_36920	COG3850	Histidine kinase
JV59_36920	COG2205	protein histidine kinase activity
JV59_36920	COG3437	response regulator, receiver
JV59_36920	COG4999	Histidine kinase
JV59_36925	COG0736	holo-[acyl-carrier-protein] synthase activity
JV59_36935	COG1381	Involved in DNA repair and RecF pathway recombination
JV59_36940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JV59_36950	COG0681	Belongs to the peptidase S26 family
JV59_36955	COG0481	GTPase activity
JV59_36960	COG3086	response to oxidative stress
JV59_36965	COG3026	antisigma factor binding
JV59_36975	COG1595	DNA-templated transcription, initiation
JV59_36980	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JV59_36995	COG0354	folic acid binding
JV59_37010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JV59_37015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JV59_37025	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JV59_37030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JV59_37040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JV59_37045	COG2271	Major facilitator Superfamily
JV59_37050	COG0584	glycerophosphoryl diester phosphodiesterase
JV59_37055	COG0440	acetolactate synthase activity
JV59_37060	COG0028	Belongs to the TPP enzyme family
JV59_37065	COG1022	Amp-dependent synthetase and ligase
JV59_37070	COG0583	DNA-binding transcription factor activity
JV59_37090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JV59_37095	COG0473	3-isopropylmalate dehydrogenase activity
JV59_37105	COG0066	3-isopropylmalate dehydratase activity
JV59_37155	COG3437	response regulator, receiver
JV59_37175	COG1854	S-ribosylhomocysteine lyase activity
JV59_37185	COG2918	glutathione biosynthetic process
JV59_37190	COG0612	Peptidase, M16
JV59_37195	COG1238	metal cluster binding
JV59_37200	COG2130	NADP-dependent
JV59_37205	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
JV59_37210	COG0511	ligase activity, forming carbon-carbon bonds
JV59_37210	COG5016	pyruvate
JV59_37215	COG3630	sodium ion export across plasma membrane
JV59_37265	COG2137	regulation of response to DNA damage stimulus
JV59_37270	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JV59_37275	COG1546	Belongs to the CinA family
JV59_37280	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JV59_37285	COG0795	lipopolysaccharide-transporting ATPase activity
JV59_37290	COG0795	lipopolysaccharide-transporting ATPase activity
JV59_37315	COG4269	membrane
JV59_37325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JV59_37330	COG0564	pseudouridine synthase activity
JV59_37345	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JV59_37360	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
JV59_37365	COG0251	oxidation-reduction process
JV59_37375	COG0039	L-malate dehydrogenase activity
JV59_37395	COG0589	response to stress
JV59_37415	COG2235	arginine
JV59_37420	COG0204	Acyl-transferase
JV59_37430	COG5007	Belongs to the BolA IbaG family
JV59_37440	COG2854	intermembrane phospholipid transfer
JV59_37445	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JV59_37450	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JV59_37455	COG1127	ABC transporter
JV59_37470	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JV59_37480	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
JV59_37485	COG1137	ATPase activity
JV59_37495	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JV59_37500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_37510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_37515	COG2239	Acts as a magnesium transporter
JV59_37555	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JV59_37560	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JV59_37705	COG3437	response regulator, receiver
JV59_37715	COG0735	belongs to the Fur family
JV59_37725	COG0529	Catalyzes the synthesis of activated sulfate
JV59_37730	COG0471	metal ion transport
JV59_37730	COG3273	potassium ion transport
JV59_37745	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JV59_37745	COG1648	precorrin-2 dehydrogenase activity
JV59_37750	COG0737	Belongs to the 5'-nucleotidase family
JV59_37760	COG2153	protein acetylation
JV59_37785	COG0203	ribosomal protein L17
JV59_37800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JV59_37805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JV59_37815	COG0201	protein transport
JV59_37825	COG1841	ribosomal large subunit assembly
JV59_37840	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JV59_37855	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JV59_37880	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JV59_37885	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JV59_37905	COG0088	Forms part of the polypeptide exit tunnel
JV59_37915	COG0051	transcription antitermination factor activity, RNA binding
JV59_37920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JV59_37925	COG0557	exoribonuclease II activity
JV59_37930	COG0402	S-adenosylhomocysteine deaminase activity
JV59_37935	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
JV59_37940	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JV59_37950	COG1047	Peptidyl-prolyl cis-trans
JV59_37965	COG2249	NAD(P)H dehydrogenase (quinone) activity
JV59_37970	COG0488	(ABC) transporter
JV59_37980	COG0429	hydrolase of the alpha beta-hydrolase fold
JV59_37985	COG3089	Belongs to the UPF0270 family
JV59_37990	COG3954	Phosphoribulokinase
JV59_37995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JV59_38015	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JV59_38080	COG1027	Aspartate ammonia-lyase
JV59_38085	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JV59_38090	COG1288	antiporter activity
JV59_38105	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JV59_38110	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
JV59_38115	COG1438	arginine binding
JV59_38120	COG4232	protein-disulfide reductase activity
JV59_38130	COG2095	MarC family integral membrane protein
JV59_38140	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JV59_38150	COG2205	protein histidine kinase activity
JV59_38150	COG0784	Response regulator, receiver
JV59_38155	COG2814	Major facilitator Superfamily
JV59_38170	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JV59_38175	COG0511	ligase activity, forming carbon-carbon bonds
JV59_38180	COG0439	Biotin carboxylase
JV59_38185	COG2264	protein methyltransferase activity
JV59_38190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JV59_38195	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JV59_38200	COG3706	GGDEF domain
JV59_38205	COG0789	Transcriptional regulator
JV59_38215	COG0151	Belongs to the GarS family
JV59_38230	COG3068	Protein conserved in bacteria
JV59_38235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JV59_38240	COG1573	uracil-dna glycosylase
JV59_38245	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JV59_38250	COG1695	Transcriptional regulator
JV59_38255	COG1045	serine acetyltransferase
JV59_38270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JV59_38305	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JV59_38310	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JV59_38315	COG1053	succinate dehydrogenase
JV59_38320	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JV59_38350	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JV59_38355	COG1609	Transcriptional regulator
JV59_38360	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JV59_38370	COG0281	malic enzyme
JV59_38380	COG0626	cystathionine gamma-synthase activity
JV59_38385	COG0460	homoserine dehydrogenase
JV59_38385	COG0527	aspartate kinase activity
JV59_38390	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JV59_38400	COG1494	fructose-1,6-bisphosphatase
JV59_38420	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JV59_38450	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JV59_38455	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JV59_38455	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JV59_38460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JV59_38490	COG2226	methyltransferase
JV59_38510	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JV59_38520	COG0318	PFAM AMP-dependent synthetase and ligase
JV59_38530	COG2089	acid synthase
JV59_38540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JV59_38545	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JV59_38555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JV59_38560	COG1086	Polysaccharide biosynthesis protein
JV59_38570	COG0438	transferase activity, transferring glycosyl groups
JV59_38605	COG1519	Transferase
JV59_38620	COG3642	lipopolysaccharide core region biosynthetic process
JV59_38625	COG0859	PFAM glycosyl transferase family 9
JV59_38630	COG0463	Glycosyl transferase, family 2
JV59_38640	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JV59_38670	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JV59_38675	COG1309	transcriptional regulator
JV59_38680	COG1560	Kdo2-lipid A biosynthetic process
JV59_38685	COG1560	Kdo2-lipid A biosynthetic process
JV59_38690	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JV59_38700	COG1561	YicC-like family, N-terminal region
JV59_38720	COG3210	domain, Protein
JV59_38725	COG2831	hemolysin activation secretion protein
JV59_38730	COG2252	PERMEase
JV59_38740	COG0848	biopolymer transport protein
JV59_38770	COG1595	DNA-templated transcription, initiation
JV59_38785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JV59_38790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JV59_38795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JV59_38800	COG1218	3'(2'),5'-bisphosphate nucleotidase
JV59_38805	COG0494	nUDIX hydrolase
JV59_38810	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JV59_38810	COG0316	Belongs to the HesB IscA family
JV59_38820	COG0596	Alpha beta hydrolase
JV59_38830	COG2183	response to ionizing radiation
JV59_38840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JV59_38845	COG0745	RESPONSE REGULATOR receiver
JV59_38860	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
JV59_38865	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
JV59_38870	COG3156	type II secretion system protein K
JV59_38875	COG4795	General secretion pathway protein
JV59_38880	COG2165	general secretion pathway protein
JV59_38885	COG2165	general secretion pathway protein
JV59_38890	COG2165	general secretion pathway protein
JV59_38895	COG1459	type II secretion system
JV59_38900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JV59_38910	COG3031	protein transport across the cell outer membrane
JV59_38915	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JV59_38925	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JV59_38935	COG0456	acetyltransferase
JV59_38940	COG1490	D-aminoacyl-tRNA deacylase activity
JV59_38960	COG0174	glutamine synthetase
JV59_38965	COG3852	Histidine kinase
JV59_38970	COG2204	response regulator
JV59_38975	COG5001	Diguanylate cyclase
JV59_38975	COG3300	MHYT domain
JV59_38980	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JV59_39020	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JV59_39035	COG0408	coproporphyrinogen oxidase activity
JV59_39045	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JV59_39050	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JV59_39055	COG0551	DNA topoisomerase type I activity
JV59_39060	COG2922	Belongs to the Smg family
JV59_39065	COG0758	DNA mediated transformation
JV59_39080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JV59_39080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JV59_39085	COG0569	domain protein
JV59_39090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JV59_39100	COG1272	protein, Hemolysin III
JV59_39105	COG4326	sporulation control protein
JV59_39115	COG3084	Protein conserved in bacteria
JV59_39125	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JV59_39130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JV59_39135	COG0204	Acyl-transferase
JV59_39145	COG0606	chelatase, subunit chli
JV59_39155	COG3978	acetolactate synthase activity
JV59_39160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JV59_39165	COG0129	dihydroxy-acid dehydratase activity
JV59_39175	COG0604	alcohol dehydrogenase
JV59_39190	COG0425	Belongs to the sulfur carrier protein TusA family
JV59_39200	COG2119	membrane
JV59_39210	COG0751	glycine-tRNA ligase activity
JV59_39215	COG3977	Valine--pyruvate aminotransferase
JV59_39220	COG0071	Belongs to the small heat shock protein (HSP20) family
JV59_39225	COG0187	DNA topoisomerase II activity
JV59_39230	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JV59_39235	COG0592	DNA-directed DNA polymerase activity
JV59_39255	COG1126	abc transporter atp-binding protein
JV59_39270	COG0706	membrane insertase activity
JV59_39275	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JV59_39280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JV59_39285	COG0445	tRNA wobble uridine modification
JV59_39295	COG1192	Involved in chromosome partitioning
JV59_39300	COG1475	DNA binding
JV59_39305	COG3312	ion transport
JV59_39325	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JV59_39330	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JV59_39335	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JV59_39340	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JV59_39345	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JV59_39355	COG0765	amino acid transport
JV59_39365	COG2814	Major facilitator Superfamily
JV59_39370	COG0583	DNA-binding transcription factor activity
JV59_39375	COG3706	GGDEF domain
JV59_39380	COG0183	Belongs to the thiolase family
JV59_39390	COG1739	Uncharacterized protein family UPF0029
JV59_39395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JV59_39450	COG2132	Multicopper oxidase
JV59_39465	COG0352	thiamine-phosphate diphosphorylase activity
JV59_39470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JV59_39490	COG0006	proline dipeptidase activity
JV59_39490	COG0006	proline dipeptidase activity
JV59_39510	COG1522	sequence-specific DNA binding
JV59_39515	COG5002	protein histidine kinase activity
JV59_39515	COG5001	Diguanylate cyclase
JV59_39520	COG0742	ribosomal rna small subunit methyltransferase
JV59_39530	COG0697	spore germination
JV59_39535	COG0589	response to stress
JV59_39540	COG1528	Iron-storage protein
JV59_39550	COG2081	HI0933 family
JV59_39580	COG1639	'signal transduction protein
JV59_39590	COG1322	Protein conserved in bacteria
JV59_39620	COG0805	protein transport
JV59_39625	COG0084	hydrolase, TatD family'
JV59_39640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JV59_39640	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JV59_39645	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JV59_39670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JV59_39675	COG0583	DNA-binding transcription factor activity
JV59_39685	COG2960	long-chain fatty acid transporting porin activity
JV59_39690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JV59_39695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_39700	COG1309	transcriptional regulator
JV59_39745	COG0747	negative chemotaxis
JV59_39755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JV59_39770	COG0745	RESPONSE REGULATOR receiver
JV59_39795	COG0477	Major facilitator Superfamily
JV59_39805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JV59_39810	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JV59_39830	COG3220	belongs to the UPF0276 family
JV59_39840	COG0210	DNA helicase
JV59_39855	COG0405	Gamma-glutamyltransferase
JV59_39860	COG1280	lysine exporter protein (LysE YggA)
JV59_39870	COG2962	Rard protein
JV59_39875	COG0514	ATP-dependent DNA helicase (RecQ)
JV59_39885	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JV59_39890	COG0248	Ppx GppA phosphatase
JV59_39900	COG3118	belongs to the thioredoxin family
JV59_39905	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JV59_39915	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JV59_39950	COG3071	HemY protein
JV59_39955	COG2959	enzyme of heme biosynthesis
JV59_39960	COG1587	Uroporphyrinogen-III synthase
JV59_39970	COG3072	Adenylate cyclase
JV59_39975	COG1965	Belongs to the frataxin family
JV59_39985	COG0019	diaminopimelate decarboxylase activity
JV59_39990	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JV59_40000	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JV59_40005	COG1011	Hydrolase
JV59_40010	COG3287	FIST C domain
JV59_40010	COG2200	EAL domain
JV59_40010	COG2199	diguanylate cyclase activity
JV59_40030	COG0561	phosphatase activity
JV59_40040	COG1280	lysine exporter protein (LysE YggA)
JV59_40045	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JV59_40050	COG0640	Transcriptional regulator
JV59_40055	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JV59_40100	COG2095	MarC family integral membrane protein
JV59_40110	COG0742	ribosomal rna small subunit methyltransferase
JV59_40115	COG0552	protein localization to endoplasmic reticulum
JV59_40120	COG2884	Cell division ATP-binding protein ftsE
JV59_40125	COG2177	Part of the ABC transporter FtsEX involved in
JV59_40130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JV59_40135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JV59_40145	COG1580	Controls the rotational direction of flagella during chemotaxis
JV59_40150	COG3161	chorismate lyase activity
JV59_40155	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JV59_40160	COG2937	Belongs to the GPAT DAPAT family
JV59_40165	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JV59_40170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JV59_40180	COG0534	Mate efflux family protein
JV59_40205	COG4206	TonB-dependent receptor
JV59_40215	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JV59_40250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JV59_40380	COG1304	FMN binding