locus-tag	class	description
IX92_00005	COG0445	tRNA wobble uridine modification
IX92_00015	COG1192	Involved in chromosome partitioning
IX92_00020	COG1475	DNA binding
IX92_00025	COG3312	ion transport
IX92_00045	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IX92_00050	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IX92_00055	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IX92_00060	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IX92_00065	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IX92_00075	COG0765	amino acid transport
IX92_00085	COG2814	Major facilitator Superfamily
IX92_00090	COG0583	DNA-binding transcription factor activity
IX92_00095	COG3706	GGDEF domain
IX92_00100	COG0183	Belongs to the thiolase family
IX92_00110	COG1739	Uncharacterized protein family UPF0029
IX92_00115	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IX92_00170	COG2132	Multicopper oxidase
IX92_00190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IX92_00200	COG2022	thiamine diphosphate biosynthetic process
IX92_00210	COG0006	proline dipeptidase activity
IX92_00230	COG1522	sequence-specific DNA binding
IX92_00235	COG5001	Diguanylate cyclase
IX92_00235	COG5002	protein histidine kinase activity
IX92_00240	COG0742	ribosomal rna small subunit methyltransferase
IX92_00250	COG0697	spore germination
IX92_00255	COG0589	response to stress
IX92_00260	COG1528	Iron-storage protein
IX92_00270	COG2081	HI0933 family
IX92_00300	COG1639	'signal transduction protein
IX92_00310	COG1322	Protein conserved in bacteria
IX92_00340	COG0805	protein transport
IX92_00345	COG0084	hydrolase, TatD family'
IX92_00360	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IX92_00360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IX92_00365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IX92_00390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IX92_00395	COG0583	DNA-binding transcription factor activity
IX92_00405	COG2960	long-chain fatty acid transporting porin activity
IX92_00410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX92_00415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX92_00420	COG1309	transcriptional regulator
IX92_00465	COG0747	negative chemotaxis
IX92_00475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IX92_00490	COG0745	RESPONSE REGULATOR receiver
IX92_00510	COG0477	Major facilitator Superfamily
IX92_00520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IX92_00525	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IX92_00545	COG3220	belongs to the UPF0276 family
IX92_00555	COG0210	DNA helicase
IX92_00570	COG0405	Gamma-glutamyltransferase
IX92_00575	COG1280	lysine exporter protein (LysE YggA)
IX92_00585	COG2962	Rard protein
IX92_00590	COG0514	ATP-dependent DNA helicase (RecQ)
IX92_00600	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IX92_00605	COG0248	Ppx GppA phosphatase
IX92_00615	COG3118	belongs to the thioredoxin family
IX92_00620	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IX92_00630	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IX92_00690	COG3071	HemY protein
IX92_00695	COG2959	enzyme of heme biosynthesis
IX92_00700	COG1587	Uroporphyrinogen-III synthase
IX92_00710	COG3072	Adenylate cyclase
IX92_00715	COG1965	Belongs to the frataxin family
IX92_00725	COG0019	diaminopimelate decarboxylase activity
IX92_00730	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IX92_00740	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IX92_00745	COG1011	Hydrolase
IX92_00750	COG3287	FIST C domain
IX92_00750	COG2199	diguanylate cyclase activity
IX92_00750	COG2200	EAL domain
IX92_00770	COG0561	phosphatase activity
IX92_00780	COG1280	lysine exporter protein (LysE YggA)
IX92_00785	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IX92_00790	COG0640	Transcriptional regulator
IX92_00795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IX92_00840	COG2095	MarC family integral membrane protein
IX92_00850	COG0742	ribosomal rna small subunit methyltransferase
IX92_00855	COG0552	protein localization to endoplasmic reticulum
IX92_00860	COG2884	Cell division ATP-binding protein ftsE
IX92_00865	COG2177	Part of the ABC transporter FtsEX involved in
IX92_00870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IX92_00875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IX92_00885	COG1580	Controls the rotational direction of flagella during chemotaxis
IX92_00890	COG3161	chorismate lyase activity
IX92_00895	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IX92_00900	COG2937	Belongs to the GPAT DAPAT family
IX92_00905	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IX92_00910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IX92_00920	COG0534	Mate efflux family protein
IX92_00945	COG4206	TonB-dependent receptor
IX92_00955	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IX92_01020	COG0646	methionine synthase
IX92_01020	COG1410	methionine synthase
IX92_01025	COG2239	Acts as a magnesium transporter
IX92_01030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX92_01040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX92_01045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IX92_01055	COG1137	ATPase activity
IX92_01060	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IX92_01070	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IX92_01075	COG0517	IMP dehydrogenase activity
IX92_01075	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IX92_01085	COG1127	ABC transporter
IX92_01090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IX92_01095	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IX92_01100	COG2854	intermembrane phospholipid transfer
IX92_01110	COG5007	Belongs to the BolA IbaG family
IX92_01120	COG0204	Acyl-transferase
IX92_01125	COG2235	arginine
IX92_01145	COG0589	response to stress
IX92_01165	COG0039	L-malate dehydrogenase activity
IX92_01175	COG0251	oxidation-reduction process
IX92_01180	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IX92_01195	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IX92_01210	COG0564	pseudouridine synthase activity
IX92_01215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IX92_01225	COG4269	membrane
IX92_01235	COG0525	valine-tRNA ligase activity
IX92_01240	COG2927	DNA polymerase III (CHI subunit)
IX92_01250	COG0795	lipopolysaccharide-transporting ATPase activity
IX92_01255	COG0795	lipopolysaccharide-transporting ATPase activity
IX92_01260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IX92_01265	COG1546	Belongs to the CinA family
IX92_01270	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IX92_01275	COG2137	regulation of response to DNA damage stimulus
IX92_01285	COG0527	aspartate kinase activity
IX92_01335	COG3630	sodium ion export across plasma membrane
IX92_01340	COG5016	pyruvate
IX92_01340	COG0511	ligase activity, forming carbon-carbon bonds
IX92_01345	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
IX92_01350	COG2130	NADP-dependent
IX92_01355	COG1238	metal cluster binding
IX92_01360	COG0612	Peptidase, M16
IX92_01365	COG2918	glutathione biosynthetic process
IX92_01375	COG1854	S-ribosylhomocysteine lyase activity
IX92_01390	COG0582	viral genome integration into host DNA
IX92_01425	COG0328	RNA-DNA hybrid ribonuclease activity
IX92_01455	COG2197	response regulator
IX92_01460	COG4251	negative regulation of phosphorylation
IX92_01485	COG0328	RNA-DNA hybrid ribonuclease activity
IX92_01525	COG2003	Belongs to the UPF0758 family
IX92_01535	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IX92_01560	COG3437	response regulator, receiver
IX92_01620	COG0473	3-isopropylmalate dehydrogenase activity
IX92_01625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IX92_01645	COG0583	DNA-binding transcription factor activity
IX92_01650	COG1022	Amp-dependent synthetase and ligase
IX92_01655	COG0028	Belongs to the TPP enzyme family
IX92_01660	COG0440	acetolactate synthase activity
IX92_01665	COG0584	glycerophosphoryl diester phosphodiesterase
IX92_01670	COG2271	Major facilitator Superfamily
IX92_01675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IX92_01685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IX92_01690	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IX92_01700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX92_01705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX92_01735	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IX92_01740	COG1595	DNA-templated transcription, initiation
IX92_01750	COG3026	antisigma factor binding
IX92_01755	COG3086	response to oxidative stress
IX92_01760	COG0481	GTPase activity
IX92_01765	COG0681	Belongs to the peptidase S26 family
IX92_01775	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IX92_01780	COG1381	Involved in DNA repair and RecF pathway recombination
IX92_01790	COG0736	holo-[acyl-carrier-protein] synthase activity
IX92_01795	COG4999	Histidine kinase
IX92_01795	COG3850	Histidine kinase
IX92_01795	COG2205	protein histidine kinase activity
IX92_01795	COG3437	response regulator, receiver
IX92_01800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IX92_01805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IX92_01810	COG3956	TIGRFAM MazG family protein
IX92_01820	COG0148	phosphopyruvate hydratase activity
IX92_01825	COG0148	phosphopyruvate hydratase activity
IX92_01830	COG0148	phosphopyruvate hydratase activity
IX92_01835	COG0617	tRNA 3'-terminal CCA addition
IX92_01840	COG3267	Type II secretory pathway component ExeA
IX92_01840	COG3409	Peptidoglycan-binding domain 1 protein
IX92_01850	COG4991	sh3 domain protein
IX92_01855	COG0306	phosphate transporter
IX92_01860	COG1392	Phosphate transport regulator
IX92_01865	COG3025	triphosphatase activity
IX92_01870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IX92_01880	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IX92_01890	COG0745	RESPONSE REGULATOR receiver
IX92_01920	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IX92_01925	COG2860	membrane
IX92_01930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IX92_01935	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IX92_01960	COG1846	Transcriptional regulator
IX92_01965	COG0534	Mate efflux family protein
IX92_01970	COG2204	response regulator
IX92_01980	COG0667	Aldo Keto reductase
IX92_01990	COG3066	DNA modification
IX92_02005	COG0730	response to heat
IX92_02015	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IX92_02020	COG1283	sodium-dependent phosphate transmembrane transporter activity
IX92_02030	COG0583	DNA-binding transcription factor activity
IX92_02035	COG0640	Transcriptional regulator
IX92_02040	COG0268	Binds directly to 16S ribosomal RNA
IX92_02045	COG0728	peptidoglycan biosynthetic process
IX92_02050	COG0196	riboflavin kinase activity
IX92_02065	COG1047	Peptidyl-prolyl cis-trans
IX92_02070	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IX92_02075	COG1966	Carbon starvation protein
IX92_02085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IX92_02090	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IX92_02105	COG1737	Transcriptional regulator
IX92_02110	COG1472	Belongs to the glycosyl hydrolase 3 family
IX92_02115	COG3279	Response regulator of the LytR AlgR family
IX92_02120	COG3275	phosphorelay sensor kinase activity
IX92_02125	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IX92_02130	COG0287	Prephenate dehydrogenase
IX92_02130	COG1605	Chorismate mutase
IX92_02135	COG0739	heme binding
IX92_02145	COG0488	(ABC) transporter
IX92_02150	COG0741	lytic transglycosylase activity
IX92_02155	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
IX92_02160	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
IX92_02165	COG5001	Diguanylate cyclase
IX92_02170	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IX92_02175	COG1605	Chorismate mutase
IX92_02175	COG0077	Prephenate dehydratase
IX92_02180	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IX92_02185	COG0741	lytic transglycosylase activity
IX92_02190	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IX92_02195	COG0564	pseudouridine synthase activity
IX92_02205	COG0542	response to heat
IX92_02245	COG0483	inositol monophosphate 1-phosphatase activity
IX92_02255	COG1959	2 iron, 2 sulfur cluster binding
IX92_02265	COG0822	iron-sulfur transferase activity
IX92_02285	COG0633	Ferredoxin
IX92_02290	COG2975	iron-sulfur cluster assembly
IX92_02295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IX92_02305	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IX92_02310	COG0583	DNA-binding transcription factor activity
IX92_02320	COG0583	DNA-binding transcription factor activity
IX92_02325	COG1022	Amp-dependent synthetase and ligase
IX92_02330	COG2169	Transcriptional regulator
IX92_02355	COG4964	Belongs to the GSP D family
IX92_02395	COG0583	DNA-binding transcription factor activity
IX92_02405	COG2169	Transcriptional regulator
IX92_02410	COG1486	melibiose metabolic process
IX92_02415	COG2211	Major facilitator Superfamily
IX92_02425	COG3408	Glycogen debranching enzyme
IX92_02425	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IX92_02445	COG0531	amino acid
IX92_02450	COG2731	YhcH YjgK YiaL family protein
IX92_02455	COG3250	beta-galactosidase activity
IX92_02460	COG1609	Transcriptional regulator
IX92_02465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IX92_02470	COG1085	galactose-1-phosphate uridylyltransferase
IX92_02480	COG2017	converts alpha-aldose to the beta-anomer
IX92_02490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IX92_02500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IX92_02500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IX92_02500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX92_02505	COG2207	Transcriptional regulator
IX92_02515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IX92_02525	COG2171	N-acyltransferase activity
IX92_02530	COG0450	alkyl hydroperoxide reductase
IX92_02535	COG0583	DNA-binding transcription factor activity
IX92_02540	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IX92_02550	COG0517	IMP dehydrogenase activity
IX92_02555	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IX92_02565	COG1862	Preprotein translocase
IX92_02570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IX92_02575	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IX92_02595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IX92_02610	COG0745	RESPONSE REGULATOR receiver
IX92_02615	COG5002	protein histidine kinase activity
IX92_02625	COG0248	Ppx GppA phosphatase
IX92_02630	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IX92_02635	COG0573	inorganic phosphate transmembrane transporter activity
IX92_02640	COG0581	inorganic phosphate transmembrane transporter activity
IX92_02645	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IX92_02650	COG0704	Plays a role in the regulation of phosphate uptake
IX92_02665	COG3141	response to X-ray
IX92_02670	COG1309	transcriptional regulator
IX92_02675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX92_02695	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IX92_02700	COG1074	ATP-dependent DNA helicase activity
IX92_02705	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IX92_02725	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IX92_02730	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IX92_02735	COG2166	iron-sulfur cluster assembly
IX92_02745	COG1426	Protein conserved in bacteria
IX92_02755	COG0124	histidyl-tRNA synthetase
IX92_02760	COG2976	Protein conserved in bacteria
IX92_02765	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IX92_02770	COG1160	GTP binding
IX92_02780	COG2199	diguanylate cyclase activity
IX92_02780	COG2203	Gaf domain
IX92_02795	COG0517	IMP dehydrogenase activity
IX92_02795	COG0516	GMP reductase activity
IX92_02810	COG1584	GPR1 FUN34 yaaH family protein
IX92_02815	COG1115	amino acid carrier protein
IX92_02820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IX92_02840	COG2873	o-acetylhomoserine
IX92_02845	COG0835	chemotaxis
IX92_02845	COG0784	Response regulator, receiver
IX92_02850	COG0204	Acyl-transferase
IX92_02870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IX92_02875	COG0668	transmembrane transport
IX92_02915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IX92_02930	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IX92_02950	COG0582	viral genome integration into host DNA
IX92_02960	COG2867	negative regulation of translational initiation
IX92_02970	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IX92_02975	COG0497	DNA recombination
IX92_02985	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IX92_02990	COG1301	dicarboxylic acid transport
IX92_02995	COG0443	Heat shock 70 kDa protein
IX92_03010	COG4970	Tfp pilus assembly protein FimT
IX92_03030	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IX92_03035	COG0590	tRNA wobble adenosine to inosine editing
IX92_03040	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IX92_03045	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IX92_03045	COG0047	phosphoribosylformylglycinamidine synthase activity
IX92_03070	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IX92_03075	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IX92_03080	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IX92_03085	COG1187	pseudouridine synthase activity
IX92_03090	COG2840	Smr protein MutS2
IX92_03115	COG3104	oligopeptide transport
IX92_03120	COG0367	asparagine synthase
IX92_03125	COG4651	solute:proton antiporter activity
IX92_03125	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IX92_03130	COG1846	Transcriptional regulator
IX92_03130	COG1940	carbohydrate kinase activity
IX92_03135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IX92_03140	COG2190	(PTS) system
IX92_03140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IX92_03140	COG1263	PTS System
IX92_03160	COG0716	FMN binding
IX92_03170	COG0596	Alpha beta hydrolase
IX92_03175	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IX92_03180	COG0033	Phosphoglucomutase
IX92_03190	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IX92_03200	COG2009	succinate dehydrogenase
IX92_03205	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IX92_03210	COG1053	succinate dehydrogenase
IX92_03215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IX92_03220	COG0567	Dehydrogenase, E1 component
IX92_03225	COG0508	dehydrogenase complex catalyzes the overall conversion of
IX92_03260	COG3098	single-species biofilm formation
IX92_03265	COG0564	pseudouridine synthase activity
IX92_03275	COG0142	geranyltranstransferase activity
IX92_03285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IX92_03295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IX92_03295	COG0301	tRNA thio-modification
IX92_03300	COG0583	DNA-binding transcription factor activity
IX92_03325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IX92_03330	COG1611	Belongs to the LOG family
IX92_03335	COG3706	GGDEF domain
IX92_03335	COG0745	RESPONSE REGULATOR receiver
IX92_03355	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
IX92_03365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IX92_03370	COG1393	Belongs to the ArsC family
IX92_03400	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
IX92_03405	COG0437	4 iron, 4 sulfur cluster binding
IX92_03410	COG3301	Polysulphide reductase, NrfD
IX92_03415	COG1138	Cytochrome C-type biogenesis protein
IX92_03420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IX92_03425	COG3088	subunit of a heme lyase
IX92_03425	COG4235	cytochrome complex assembly
IX92_03435	COG2837	iron assimilation
IX92_03455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IX92_03465	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IX92_03475	COG1516	flagellar protein fliS
IX92_03480	COG2204	response regulator
IX92_03485	COG4191	Histidine kinase
IX92_03490	COG2204	response regulator
IX92_03495	COG1677	Flagellar hook-basal body complex protein FliE
IX92_03505	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IX92_03555	COG1987	bacterial-type flagellum assembly
IX92_03560	COG1684	flagellar biosynthetic protein fliR
IX92_03575	COG2890	protein-(glutamine-N5) methyltransferase activity
IX92_03580	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IX92_03590	COG2860	membrane
IX92_03595	COG3101	peptidyl-lysine hydroxylation
IX92_03625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IX92_03630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IX92_03635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IX92_03645	COG0101	tRNA pseudouridine synthase activity
IX92_03655	COG0285	dihydrofolate synthase activity
IX92_03660	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IX92_03665	COG1286	toxin biosynthetic process
IX92_03670	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IX92_03675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IX92_03680	COG1121	(ABC) transporter
IX92_03685	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IX92_03690	COG4977	sequence-specific DNA binding
IX92_03695	COG1918	ferrous iron import across plasma membrane
IX92_03700	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IX92_03715	COG0018	arginyl-trna synthetase
IX92_03720	COG3102	Protein conserved in bacteria
IX92_03725	COG1025	Belongs to the peptidase M16 family
IX92_03730	COG2062	phosphohistidine phosphatase, SixA
IX92_03745	COG0455	bacterial-type flagellum organization
IX92_03760	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IX92_03765	COG2198	Histidine kinase
IX92_03765	COG0643	Histidine kinase
IX92_03775	COG1192	Involved in chromosome partitioning
IX92_03785	COG0835	chemotaxis
IX92_03795	COG4133	protoheme IX ABC transporter activity
IX92_03800	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IX92_03805	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IX92_03810	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IX92_03820	COG1138	Cytochrome C-type biogenesis protein
IX92_03825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IX92_03830	COG4235	cytochrome complex assembly
IX92_03830	COG3088	subunit of a heme lyase
IX92_03840	COG2853	Lipoprotein
IX92_03845	COG2067	long-chain fatty acid transport protein
IX92_03850	COG2067	long-chain fatty acid transport protein
IX92_03865	COG0183	Belongs to the thiolase family
IX92_03875	COG0778	Nitroreductase
IX92_03880	COG0583	DNA-binding transcription factor activity
IX92_03885	COG0745	RESPONSE REGULATOR receiver
IX92_03895	COG2832	Protein of unknown function (DUF454)
IX92_03900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IX92_03910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IX92_03915	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IX92_03940	COG0745	RESPONSE REGULATOR receiver
IX92_03945	COG2205	protein histidine kinase activity
IX92_03950	COG1653	transport
IX92_03965	COG3842	ATPase activity
IX92_03970	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IX92_03975	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IX92_03980	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IX92_04015	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IX92_04020	COG0776	regulation of translation
IX92_04025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IX92_04030	COG1555	photosystem II stabilization
IX92_04040	COG0539	negative regulation of cytoplasmic translation
IX92_04050	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IX92_04055	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IX92_04060	COG0284	orotidine-5'-phosphate decarboxylase activity
IX92_04095	COG4120	Belongs to the binding-protein-dependent transport system permease family
IX92_04105	COG3706	GGDEF domain
IX92_04110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IX92_04130	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IX92_04135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IX92_04145	COG0252	asparaginase activity
IX92_04150	COG0616	signal peptide processing
IX92_04155	COG0446	pyridine nucleotide-disulphide oxidoreductase
IX92_04155	COG1902	pentaerythritol trinitrate reductase activity
IX92_04160	COG0788	formyltetrahydrofolate deformylase activity
IX92_04170	COG1199	ATP-dependent helicase activity
IX92_04175	COG1214	PFAM Peptidase M22, glycoprotease
IX92_04190	COG2267	carboxylic ester hydrolase activity
IX92_04195	COG0318	PFAM AMP-dependent synthetase and ligase
IX92_04200	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IX92_04205	COG0659	secondary active sulfate transmembrane transporter activity
IX92_04210	COG1530	ribonuclease E activity
IX92_04215	COG0564	pseudouridine synthase activity
IX92_04220	COG0424	maF-like protein
IX92_04225	COG1399	metal-binding, possibly nucleic acid-binding protein
IX92_04240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IX92_04265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IX92_04270	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IX92_04275	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IX92_04280	COG0470	DNA polymerase III
IX92_04285	COG0084	hydrolase, TatD family'
IX92_04290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IX92_04290	COG1263	PTS System
IX92_04300	COG0733	neurotransmitter:sodium symporter activity
IX92_04315	COG4667	esterase of the alpha-beta hydrolase superfamily
IX92_04320	COG0469	pyruvate kinase activity
IX92_04325	COG1940	carbohydrate kinase activity
IX92_04330	COG0784	Response regulator, receiver
IX92_04330	COG0835	chemotaxis
IX92_04350	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_04355	COG0616	signal peptide processing
IX92_04360	COG0513	Belongs to the DEAD box helicase family
IX92_04375	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IX92_04380	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IX92_04395	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IX92_04400	COG0436	Aminotransferase
IX92_04405	COG1169	isochorismate synthase
IX92_04410	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IX92_04415	COG0596	Alpha beta hydrolase
IX92_04425	COG1441	menaquinone biosynthetic process
IX92_04435	COG2855	membrane
IX92_04440	COG0477	Major facilitator Superfamily
IX92_04465	COG1522	sequence-specific DNA binding
IX92_04480	COG1946	Acyl-CoA thioesterase
IX92_04485	COG3126	Type III secretion system lipoprotein chaperone (YscW)
IX92_04500	COG3706	GGDEF domain
IX92_04520	COG1414	Transcriptional regulator
IX92_04525	COG0280	phosphate acetyltransferase
IX92_04530	COG0730	response to heat
IX92_04550	COG2855	membrane
IX92_04565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IX92_04570	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IX92_04575	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IX92_04595	COG1472	Belongs to the glycosyl hydrolase 3 family
IX92_04600	COG3876	Protein conserved in bacteria
IX92_04605	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IX92_04610	COG1215	transferase activity, transferring glycosyl groups
IX92_04625	COG3397	chitin binding
IX92_04630	COG1770	oligopeptidase
IX92_04640	COG3227	Zinc metalloprotease (Elastase)
IX92_04650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX92_04660	COG0577	efflux transmembrane transporter activity
IX92_04670	COG0577	efflux transmembrane transporter activity
IX92_04670	COG1136	(ABC) transporter
IX92_04690	COG0330	HflC and HflK could
IX92_04700	COG0840	transmembrane signaling receptor activity
IX92_04705	COG1404	Belongs to the peptidase S8 family
IX92_04715	COG0840	transmembrane signaling receptor activity
IX92_04730	COG3706	GGDEF domain
IX92_04735	COG2067	long-chain fatty acid transport protein
IX92_04750	COG0601	transmembrane transport
IX92_04755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IX92_04760	COG0444	Belongs to the ABC transporter superfamily
IX92_04770	COG0435	Glutathione S-transferase
IX92_04775	COG3706	GGDEF domain
IX92_04780	COG0857	belongs to the CobB CobQ family
IX92_04780	COG0280	phosphate acetyltransferase
IX92_04790	COG3092	negative regulation of chromosome organization
IX92_04795	COG0686	Belongs to the AlaDH PNT family
IX92_04805	COG1674	ftsk spoiiie
IX92_04820	COG2186	Transcriptional regulator
IX92_04835	COG0537	adenosine 5'-monophosphoramidase activity
IX92_04865	COG1252	NADH dehydrogenase
IX92_04885	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IX92_04895	COG4591	ABC-type transport system involved in lipoprotein release permease component
IX92_04900	COG1136	(ABC) transporter
IX92_04905	COG4591	ABC-type transport system involved in lipoprotein release permease component
IX92_04915	COG2333	competence protein COMEC
IX92_04915	COG0658	competence protein
IX92_04920	COG1132	(ABC) transporter
IX92_04935	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IX92_04940	COG2719	SpoVR family
IX92_04945	COG2718	Belongs to the UPF0229 family
IX92_04950	COG2766	serine protein kinase
IX92_04955	COG3713	MltA-interacting MipA family protein
IX92_04970	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IX92_04985	COG1882	Formate acetyltransferase
IX92_05005	COG4215	(ABC) transporter
IX92_05020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IX92_05025	COG1012	belongs to the aldehyde dehydrogenase family
IX92_05025	COG1454	alcohol dehydrogenase
IX92_05030	COG1737	Transcriptional regulator
IX92_05035	COG0076	glutamate decarboxylase activity
IX92_05045	COG2431	L-lysine efflux transmembrane transporter activity
IX92_05055	COG3070	regulator of competence-specific genes
IX92_05070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX92_05070	COG4191	Histidine kinase
IX92_05080	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IX92_05090	COG1032	radical SAM domain protein
IX92_05115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IX92_05120	COG1764	response to oxidative stress
IX92_05125	COG1846	Transcriptional regulator
IX92_05135	COG0583	DNA-binding transcription factor activity
IX92_05145	COG0673	inositol 2-dehydrogenase activity
IX92_05150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IX92_05170	COG0840	transmembrane signaling receptor activity
IX92_05175	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IX92_05190	COG3152	Membrane
IX92_05235	COG1858	cytochrome C peroxidase
IX92_05245	COG0443	Heat shock 70 kDa protein
IX92_05290	COG1643	Atp-dependent helicase
IX92_05300	COG1301	dicarboxylic acid transport
IX92_05305	COG0159	tryptophan synthase activity
IX92_05310	COG0133	tryptophan synthase activity
IX92_05315	COG0135	phosphoribosylanthranilate isomerase activity
IX92_05315	COG0134	indole-3-glycerol-phosphate synthase activity
IX92_05320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IX92_05325	COG0512	Glutamine amidotransferase of anthranilate synthase
IX92_05330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IX92_05340	COG0613	PHP domain protein
IX92_05345	COG0009	L-threonylcarbamoyladenylate synthase
IX92_05360	COG1187	pseudouridine synthase activity
IX92_05365	COG0384	phenazine biosynthesis protein PhzF
IX92_05375	COG2814	Major facilitator Superfamily
IX92_05380	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IX92_05385	COG4988	ABC transporter
IX92_05390	COG0492	ferredoxin-NADP+ reductase activity
IX92_05405	COG2175	clavaminate synthase activity
IX92_05420	COG0612	Peptidase, M16
IX92_05430	COG2949	membrane
IX92_05440	COG0281	malic enzyme
IX92_05445	COG1643	Atp-dependent helicase
IX92_05460	COG1448	Aminotransferase
IX92_05465	COG2770	Histidine kinase
IX92_05465	COG3437	response regulator, receiver
IX92_05475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IX92_05485	COG0017	Asparaginyl-tRNA synthetase
IX92_05500	COG0814	amino acid
IX92_05510	COG1760	l-serine dehydratase
IX92_05515	COG0814	amino acid
IX92_05520	COG0494	nUDIX hydrolase
IX92_05530	COG2205	protein histidine kinase activity
IX92_05530	COG0784	Response regulator, receiver
IX92_05550	COG3106	COG3106 Predicted ATPase
IX92_05560	COG3283	Transcriptional regulator of aromatic amino acids metabolism
IX92_05565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IX92_05585	COG3706	GGDEF domain
IX92_05595	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IX92_05620	COG2989	Protein conserved in bacteria
IX92_05625	COG3108	Peptidase M15
IX92_05630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IX92_05645	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IX92_05680	COG4667	esterase of the alpha-beta hydrolase superfamily
IX92_05685	COG0783	Belongs to the Dps family
IX92_05695	COG0531	amino acid
IX92_05700	COG2962	Rard protein
IX92_05710	COG0791	NLP P60 protein
IX92_05900	COG4628	conserved protein (DUF2132)
IX92_05910	COG0456	acetyltransferase
IX92_05920	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IX92_05930	COG0730	response to heat
IX92_05940	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_05950	COG2824	Alkylphosphonate utilization operon protein PhnA
IX92_05965	COG0456	acetyltransferase
IX92_05985	COG3040	lipid binding
IX92_06000	COG3122	Protein conserved in bacteria
IX92_06055	COG0454	-acetyltransferase
IX92_06060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IX92_06085	COG0456	acetyltransferase
IX92_06095	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IX92_06100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IX92_06115	COG2195	Cleaves the N-terminal amino acid of tripeptides
IX92_06125	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IX92_06135	COG0625	glutathione transferase activity
IX92_06150	COG2885	chlorophyll binding
IX92_06165	COG0247	lactate metabolic process
IX92_06165	COG0277	FAD linked oxidase domain protein
IX92_06180	COG2986	histidine ammonia-lyase
IX92_06190	COG0010	Belongs to the arginase family
IX92_06195	COG1228	amidohydrolase
IX92_06200	COG2188	Transcriptional regulator
IX92_06205	COG4326	sporulation control protein
IX92_06225	COG0500	methyltransferase
IX92_06245	COG1346	cytolysis
IX92_06255	COG2925	Exonuclease
IX92_06295	COG0702	epimerase
IX92_06300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IX92_06310	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IX92_06320	COG0406	alpha-ribazole phosphatase activity
IX92_06335	COG4139	cobalamin transport
IX92_06355	COG2203	Gaf domain
IX92_06355	COG2199	diguanylate cyclase activity
IX92_06365	COG2814	Major facilitator Superfamily
IX92_06375	COG1119	ATPase activity
IX92_06455	COG1451	nucleotide metabolic process
IX92_06470	COG3063	Type IV pilus biogenesis stability protein PilW
IX92_06475	COG0596	Alpha beta hydrolase
IX92_06475	COG0508	dehydrogenase complex catalyzes the overall conversion of
IX92_06495	COG5001	Diguanylate cyclase
IX92_06495	COG2203	Gaf domain
IX92_06495	COG3706	GGDEF domain
IX92_06495	COG4251	negative regulation of phosphorylation
IX92_06510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX92_06535	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IX92_06540	COG0515	serine threonine protein kinase
IX92_06645	COG3501	Rhs element vgr protein
IX92_06660	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IX92_06665	COG0372	Belongs to the citrate synthase family
IX92_06675	COG2828	Protein conserved in bacteria
IX92_06695	COG0561	phosphatase activity
IX92_06700	COG0602	queuosine metabolic process
IX92_06730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IX92_06735	COG0840	transmembrane signaling receptor activity
IX92_06740	COG1254	Belongs to the acylphosphatase family
IX92_06745	COG2920	part of a sulfur-relay system
IX92_06750	COG0670	Belongs to the BI1 family
IX92_06755	COG1126	abc transporter atp-binding protein
IX92_06760	COG0765	amino acid transport
IX92_06765	COG4597	amino acid ABC transporter
IX92_06770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX92_06780	COG1666	GTP binding
IX92_06785	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IX92_06790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IX92_06815	COG3008	intermembrane lipid transfer
IX92_06820	COG2995	paraquat-inducible protein a
IX92_06825	COG1132	(ABC) transporter
IX92_06830	COG1956	GAF domain-containing protein
IX92_06835	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
IX92_06850	COG0308	aminopeptidase N
IX92_06865	COG0167	dihydroorotate dehydrogenase activity
IX92_06885	COG0488	(ABC) transporter
IX92_06900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IX92_06905	COG1067	ATP-dependent peptidase activity
IX92_06965	COG0789	Transcriptional regulator
IX92_07085	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IX92_07090	COG0840	transmembrane signaling receptor activity
IX92_07225	COG3424	synthase
IX92_07240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IX92_07365	COG3278	Belongs to the heme-copper respiratory oxidase family
IX92_07380	COG2010	Cytochrome c
IX92_07390	COG2217	Heavy metal translocating P-type atpase
IX92_07405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IX92_07410	COG0589	response to stress
IX92_07435	COG3842	ATPase activity
IX92_07440	COG1176	ABC-type spermidine putrescine transport system, permease component I
IX92_07445	COG1177	transmembrane transport
IX92_07450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IX92_07455	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IX92_07460	COG2199	diguanylate cyclase activity
IX92_07465	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IX92_07470	COG0004	ammonium transporteR
IX92_07485	COG0437	4 iron, 4 sulfur cluster binding
IX92_07490	COG3383	formate dehydrogenase (NAD+) activity
IX92_07490	COG0243	molybdopterin cofactor binding
IX92_07520	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IX92_07530	COG3038	cytochrome b561
IX92_07560	COG0583	DNA-binding transcription factor activity
IX92_07570	COG0583	DNA-binding transcription factor activity
IX92_07575	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IX92_07595	COG0069	glutamate synthase activity
IX92_07610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX92_07625	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_07640	COG0488	(ABC) transporter
IX92_07650	COG1595	DNA-templated transcription, initiation
IX92_07665	COG3852	Histidine kinase
IX92_07680	COG4662	Binding-protein-dependent transport system inner membrane component
IX92_07685	COG3842	ATPase activity
IX92_07690	COG0746	molybdenum cofactor guanylyltransferase activity
IX92_07695	COG0303	'Molybdopterin
IX92_07725	COG1940	carbohydrate kinase activity
IX92_07740	COG0840	transmembrane signaling receptor activity
IX92_07745	COG0791	NLP P60 protein
IX92_07765	COG0307	riboflavin synthase, alpha
IX92_07815	COG2204	response regulator
IX92_07825	COG0438	transferase activity, transferring glycosyl groups
IX92_07830	COG0438	transferase activity, transferring glycosyl groups
IX92_07860	COG0297	glycogen (starch) synthase activity
IX92_07870	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IX92_07905	COG4774	siderophore transport
IX92_07925	COG4615	Cyclic peptide transporter
IX92_07935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IX92_07940	COG1120	ATPase activity
IX92_07945	COG2977	Belongs to the P-Pant transferase superfamily
IX92_07950	COG1929	Belongs to the glycerate kinase type-1 family
IX92_07955	COG3835	regulator
IX92_07965	COG2814	Major facilitator Superfamily
IX92_07975	COG1288	antiporter activity
IX92_07985	COG2186	Transcriptional regulator
IX92_07995	COG3713	MltA-interacting MipA family protein
IX92_08005	COG0745	RESPONSE REGULATOR receiver
IX92_08015	COG0583	DNA-binding transcription factor activity
IX92_08035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IX92_08055	COG2116	formate transmembrane transporter activity
IX92_08060	COG2146	nitrite reductase [NAD(P)H] activity
IX92_08065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IX92_08095	COG4565	transcriptional regulatory protein
IX92_08100	COG3290	protein histidine kinase activity
IX92_08120	COG0848	biopolymer transport protein
IX92_08125	COG0811	peptide transport
IX92_08130	COG0811	peptide transport
IX92_08145	COG2205	protein histidine kinase activity
IX92_08150	COG0745	RESPONSE REGULATOR receiver
IX92_08155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IX92_08195	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IX92_08200	COG1328	CTP reductase activity
IX92_08205	COG0840	transmembrane signaling receptor activity
IX92_08215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IX92_08220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IX92_08225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IX92_08230	COG0633	Ferredoxin
IX92_08255	COG0019	diaminopimelate decarboxylase activity
IX92_08300	COG1136	(ABC) transporter
IX92_08305	COG0534	Mate efflux family protein
IX92_08310	COG0702	epimerase
IX92_08320	COG2814	Major facilitator Superfamily
IX92_08330	COG1061	Type III restriction enzyme res subunit
IX92_08345	COG2205	protein histidine kinase activity
IX92_08370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX92_08375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX92_08395	COG0463	Glycosyl transferase, family 2
IX92_08405	COG2188	Transcriptional regulator
IX92_08410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IX92_08410	COG1263	PTS System
IX92_08415	COG1621	beta-fructofuranosidase activity
IX92_08425	COG0583	DNA-binding transcription factor activity
IX92_08430	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IX92_08460	COG4221	oxidoreductase activity
IX92_08495	COG0307	riboflavin synthase, alpha
IX92_08545	COG0242	peptide deformylase activity
IX92_08550	COG0519	Catalyzes the synthesis of GMP from XMP
IX92_08565	COG4580	involved in the transport of maltose and maltodextrins
IX92_08570	COG0778	Nitroreductase
IX92_08630	COG5001	Diguanylate cyclase
IX92_08630	COG3300	MHYT domain
IX92_08665	COG1115	amino acid carrier protein
IX92_08670	COG1280	lysine exporter protein (LysE YggA)
IX92_08675	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IX92_08680	COG0352	thiamine-phosphate diphosphorylase activity
IX92_08685	COG0583	DNA-binding transcription factor activity
IX92_08710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IX92_08720	COG1012	belongs to the aldehyde dehydrogenase family
IX92_08730	COG0583	DNA-binding transcription factor activity
IX92_08780	COG1609	Transcriptional regulator
IX92_08785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IX92_08810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IX92_08815	COG1609	Transcriptional regulator
IX92_08825	COG0642	Histidine kinase
IX92_08830	COG0745	RESPONSE REGULATOR receiver
IX92_08850	COG1858	cytochrome C peroxidase
IX92_08855	COG0784	Response regulator, receiver
IX92_08855	COG2205	protein histidine kinase activity
IX92_08860	COG0784	Response regulator, receiver
IX92_08860	COG2205	protein histidine kinase activity
IX92_08865	COG0488	(ABC) transporter
IX92_08870	COG3437	response regulator, receiver
IX92_08880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IX92_08895	COG1216	Glycosyl transferase, family 2
IX92_08905	COG0673	inositol 2-dehydrogenase activity
IX92_08910	COG3718	enzyme involved in inositol metabolism
IX92_08935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IX92_08940	COG0673	inositol 2-dehydrogenase activity
IX92_08945	COG3962	Belongs to the TPP enzyme family
IX92_08955	COG0477	Major facilitator Superfamily
IX92_08955	COG2814	Major facilitator Superfamily
IX92_08975	COG0183	Belongs to the thiolase family
IX92_08980	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IX92_09020	COG3962	Belongs to the TPP enzyme family
IX92_09025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IX92_09035	COG1129	ABC transporter
IX92_09040	COG4211	Belongs to the binding-protein-dependent transport system permease family
IX92_09050	COG0277	FAD linked oxidase domain protein
IX92_09060	COG0583	DNA-binding transcription factor activity
IX92_09080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IX92_09085	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IX92_09105	COG1621	beta-fructofuranosidase activity
IX92_09120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IX92_09120	COG1263	PTS System
IX92_09125	COG1335	isochorismatase
IX92_09130	COG1741	Belongs to the pirin family
IX92_09175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IX92_09175	COG0072	phenylalanine-tRNA ligase activity
IX92_09185	COG3706	GGDEF domain
IX92_09210	COG2133	pyrroloquinoline quinone binding
IX92_09220	COG1902	pentaerythritol trinitrate reductase activity
IX92_09250	COG0322	excinuclease ABC activity
IX92_09255	COG2197	response regulator
IX92_09270	COG0417	DNA replication proofreading
IX92_09285	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IX92_09290	COG3099	Belongs to the UPF0263 family
IX92_09325	COG1607	acyl-coa hydrolase
IX92_09330	COG2350	Protein conserved in bacteria
IX92_09345	COG3313	Fe-S protein
IX92_09355	COG4134	Bacterial extracellular solute-binding protein
IX92_09360	COG4135	transport system, permease component
IX92_09365	COG4136	ATPase activity
IX92_09370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IX92_09375	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IX92_09380	COG0564	pseudouridine synthase activity
IX92_09385	COG0733	neurotransmitter:sodium symporter activity
IX92_09395	COG0626	cystathionine gamma-synthase activity
IX92_09400	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IX92_09405	COG5380	lipid catabolic process
IX92_09410	COG2818	Glycosylase
IX92_09430	COG1983	PspC domain protein
IX92_09440	COG1842	Phage shock protein A
IX92_09445	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IX92_09455	COG4168	peptide transport system, permease
IX92_09460	COG4171	peptide transport system, permease
IX92_09470	COG4172	Belongs to the ABC transporter superfamily
IX92_09485	COG1227	inorganic diphosphatase activity
IX92_09495	COG0217	transcriptional regulatory protein
IX92_09500	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IX92_09500	COG0140	phosphoribosyl-ATP diphosphatase activity
IX92_09505	COG0107	imidazoleglycerol-phosphate synthase activity
IX92_09515	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IX92_09520	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IX92_09520	COG0131	Imidazoleglycerol-phosphate dehydratase
IX92_09530	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IX92_09540	COG1757	Na H antiporter
IX92_09550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IX92_09560	COG0482	sulfurtransferase activity
IX92_09570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IX92_09580	COG2268	Band 7 protein
IX92_09590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IX92_09620	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IX92_09625	COG2226	methyltransferase
IX92_09625	COG1073	alpha beta
IX92_09630	COG0156	8-amino-7-oxononanoate synthase activity
IX92_09640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IX92_09655	COG1199	ATP-dependent helicase activity
IX92_09660	COG0730	response to heat
IX92_09675	COG2850	peptidyl-arginine hydroxylation
IX92_09680	COG0840	transmembrane signaling receptor activity
IX92_09685	COG0708	Exodeoxyribonuclease III
IX92_09690	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IX92_09695	COG1960	acyl-CoA dehydrogenase activity
IX92_09715	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IX92_09720	COG0463	Glycosyl transferase, family 2
IX92_09725	COG0745	RESPONSE REGULATOR receiver
IX92_09730	COG5002	protein histidine kinase activity
IX92_09730	COG3850	Histidine kinase
IX92_09745	COG1940	carbohydrate kinase activity
IX92_09760	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IX92_09765	COG1881	PFAM PEBP family protein
IX92_09770	COG1902	pentaerythritol trinitrate reductase activity
IX92_09790	COG0784	Response regulator, receiver
IX92_09790	COG5002	protein histidine kinase activity
IX92_09810	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IX92_09820	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IX92_09825	COG2885	chlorophyll binding
IX92_09845	COG0811	peptide transport
IX92_09850	COG0824	Thioesterase
IX92_09860	COG4890	Cyd operon protein YbgT
IX92_09865	COG1294	oxidase, subunit
IX92_09870	COG1271	oxidase subunit
IX92_09875	COG2255	four-way junction helicase activity
IX92_09880	COG0632	four-way junction helicase activity
IX92_09885	COG0840	transmembrane signaling receptor activity
IX92_09890	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IX92_09910	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_09925	COG0243	molybdopterin cofactor binding
IX92_09930	COG3005	denitrification pathway
IX92_09935	COG4459	periplasmic nitrate reductase
IX92_09940	COG0390	transport system, permease component
IX92_09945	COG2116	formate transmembrane transporter activity
IX92_09970	COG0542	response to heat
IX92_09975	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IX92_09980	COG1278	Cold shock
IX92_09990	COG1187	pseudouridine synthase activity
IX92_10000	COG1801	Protein of unknown function DUF72
IX92_10010	COG0500	methyltransferase
IX92_10015	COG0189	ligase activity
IX92_10015	COG4067	protein conserved in archaea
IX92_10045	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
IX92_10050	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IX92_10060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IX92_10065	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IX92_10070	COG0745	RESPONSE REGULATOR receiver
IX92_10085	COG3070	regulator of competence-specific genes
IX92_10110	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IX92_10115	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IX92_10140	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IX92_10145	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IX92_10150	COG1435	thymidine kinase activity
IX92_10155	COG0215	cysteine-tRNA ligase activity
IX92_10160	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IX92_10170	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IX92_10175	COG3012	SEC-C Motif Domain Protein
IX92_10180	COG3139	Protein of unknown function (DUF1315)
IX92_10190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IX92_10205	COG0840	transmembrane signaling receptor activity
IX92_10210	COG2226	methyltransferase
IX92_10225	COG1785	Belongs to the alkaline phosphatase family
IX92_10245	COG0668	transmembrane transport
IX92_10250	COG2983	Belongs to the UPF0260 family
IX92_10260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IX92_10265	COG0583	DNA-binding transcription factor activity
IX92_10270	COG2951	lytic endotransglycosylase activity
IX92_10275	COG3100	YcgL domain-containing protein
IX92_10285	COG2894	cell division
IX92_10295	COG1012	belongs to the aldehyde dehydrogenase family
IX92_10295	COG1454	alcohol dehydrogenase
IX92_10300	COG2095	MarC family integral membrane protein
IX92_10305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IX92_10310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IX92_10315	COG1757	Na H antiporter
IX92_10340	COG3082	Protein of unknown function (DUF1414)
IX92_10345	COG3083	sulfuric ester hydrolase activity
IX92_10380	COG3852	Histidine kinase
IX92_10410	COG0123	including yeast histone deacetylase and acetoin utilization protein
IX92_10420	COG1881	PFAM PEBP family protein
IX92_10430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IX92_10435	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IX92_10455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IX92_10460	COG0302	gtp cyclohydrolase
IX92_10460	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IX92_10465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IX92_10470	COG0302	gtp cyclohydrolase
IX92_10480	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IX92_10490	COG2982	Protein involved in outer membrane biogenesis
IX92_10495	COG0572	uridine kinase
IX92_10500	COG0489	protein tyrosine kinase activity
IX92_10505	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IX92_10505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IX92_10545	COG0517	IMP dehydrogenase activity
IX92_10555	COG3706	GGDEF domain
IX92_10560	COG0314	molybdopterin synthase activity
IX92_10565	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IX92_10570	COG0315	cyclic pyranopterin monophosphate synthase activity
IX92_10575	COG0521	Mo-molybdopterin cofactor biosynthetic process
IX92_10580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IX92_10585	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IX92_10590	COG2198	Histidine kinase
IX92_10600	COG0556	nucleotide-excision repair
IX92_10615	COG0739	heme binding
IX92_10640	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IX92_10655	COG2204	response regulator
IX92_10660	COG2885	chlorophyll binding
IX92_10680	COG1987	bacterial-type flagellum assembly
IX92_10690	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IX92_10705	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IX92_10710	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IX92_10715	COG1516	flagellar protein fliS
IX92_10730	COG1580	Controls the rotational direction of flagella during chemotaxis
IX92_10735	COG1191	sigma factor activity
IX92_10740	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IX92_10745	COG1360	Flagellar Motor Protein
IX92_10775	COG1706	bacterial-type flagellum-dependent cell motility
IX92_10780	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IX92_10785	COG4786	Flagellar basal body rod
IX92_10790	COG4787	bacterial-type flagellum-dependent cell motility
IX92_10795	COG1749	Flagellar hook protein flgE
IX92_10800	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IX92_10805	COG1558	bacterial-type flagellum-dependent cell motility
IX92_10810	COG1815	bacterial-type flagellum-dependent cell motility
IX92_10830	COG1388	LysM domain
IX92_10830	COG0741	lytic transglycosylase activity
IX92_10835	COG4657	Part of a membrane complex involved in electron transport
IX92_10845	COG4656	Part of a membrane complex involved in electron transport
IX92_10850	COG4658	electron transport chain
IX92_10865	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IX92_10895	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IX92_10935	COG3384	dioxygenase
IX92_10965	COG0346	lactoylglutathione lyase activity
IX92_10985	COG2056	Na+-H+ antiporter family
IX92_10995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IX92_11000	COG2716	regulation of RNA biosynthetic process
IX92_11005	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IX92_11025	COG4783	chaperone-mediated protein folding
IX92_11030	COG1393	Belongs to the ArsC family
IX92_11055	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IX92_11070	COG2912	Transglutaminase-like superfamily
IX92_11075	COG3094	Invasion gene expression up-regulator, SirB
IX92_11080	COG2890	protein-(glutamine-N5) methyltransferase activity
IX92_11105	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IX92_11115	COG0012	GTP binding
IX92_11225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IX92_11230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IX92_11235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IX92_11245	COG3951	Flagellar rod assembly protein muramidase FlgJ
IX92_11245	COG1705	Flagellar rod assembly protein muramidase FlgJ
IX92_11250	COG1706	bacterial-type flagellum-dependent cell motility
IX92_11255	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IX92_11260	COG4786	Flagellar basal body rod
IX92_11265	COG4787	bacterial-type flagellum-dependent cell motility
IX92_11270	COG1749	Flagellar hook protein flgE
IX92_11275	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IX92_11280	COG1558	bacterial-type flagellum-dependent cell motility
IX92_11285	COG1815	bacterial-type flagellum-dependent cell motility
IX92_11290	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IX92_11295	COG0784	Response regulator, receiver
IX92_11295	COG0835	chemotaxis
IX92_11305	COG2747	anti-sigma28 factor FlgM
IX92_11345	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IX92_11355	COG2194	sulfuric ester hydrolase activity
IX92_11395	COG2217	Heavy metal translocating P-type atpase
IX92_11395	COG2608	mercury ion transmembrane transporter activity
IX92_11415	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IX92_11425	COG0326	Molecular chaperone. Has ATPase activity
IX92_11430	COG3710	Transcriptional regulator
IX92_11450	COG0622	Phosphoesterase
IX92_11475	COG1090	epimerase
IX92_11480	COG0300	oxidoreductase activity
IX92_11485	COG3118	belongs to the thioredoxin family
IX92_11490	COG0330	HflC and HflK could
IX92_11510	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IX92_11515	COG3115	cell septum assembly
IX92_11520	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
IX92_11525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IX92_11530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX92_11535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IX92_11540	COG2190	(PTS) system
IX92_11545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX92_11555	COG1702	phosphate starvation-inducible protein PhoH
IX92_11560	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IX92_11565	COG4535	Mg2 and Co2 transporter CorC
IX92_11570	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IX92_11575	COG2888	peptidyl-tyrosine sulfation
IX92_11580	COG0495	leucyl-tRNA aminoacylation
IX92_11585	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
IX92_11590	COG1466	dna polymerase III delta subunit
IX92_11595	COG0799	negative regulation of ribosome biogenesis
IX92_11600	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IX92_11605	COG0768	penicillin binding
IX92_11610	COG0772	Belongs to the SEDS family
IX92_11615	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IX92_11620	COG1686	Belongs to the peptidase S11 family
IX92_11635	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IX92_11650	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IX92_11660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX92_11665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX92_11690	COG0366	Alpha amylase catalytic
IX92_11695	COG1263	PTS System
IX92_11695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IX92_11700	COG1609	Transcriptional regulator
IX92_11710	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IX92_11715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IX92_11720	COG2011	ABC-type metal ion transport system permease component
IX92_11725	COG1464	Belongs to the NlpA lipoprotein family
IX92_11735	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IX92_11745	COG1720	tRNA m6t6A37 methyltransferase activity
IX92_11755	COG0121	glutamine amidotransferase
IX92_11760	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IX92_11765	COG1960	acyl-CoA dehydrogenase activity
IX92_11775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IX92_11785	COG2226	methyltransferase
IX92_11795	COG0741	lytic transglycosylase activity
IX92_11795	COG1388	LysM domain
IX92_11810	COG0347	Belongs to the P(II) protein family
IX92_11820	COG0037	tRNA processing
IX92_11825	COG0825	malonyl-CoA metabolic process
IX92_11830	COG0587	DNA-directed DNA polymerase activity
IX92_11835	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IX92_11855	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IX92_11860	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IX92_11865	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IX92_11870	COG0750	zinc metalloprotease
IX92_11880	COG0575	Belongs to the CDS family
IX92_11885	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IX92_11890	COG0233	cytoplasmic translational termination
IX92_11895	COG0528	UMP kinase activity
IX92_11905	COG0052	Belongs to the universal ribosomal protein uS2 family
IX92_11910	COG0024	Methionine aminopeptidase
IX92_11925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IX92_11930	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IX92_11955	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IX92_11955	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IX92_11960	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IX92_11965	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IX92_11970	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IX92_11985	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IX92_11990	COG2252	PERMEase
IX92_11995	COG2195	Cleaves the N-terminal amino acid of tripeptides
IX92_12000	COG4067	protein conserved in archaea
IX92_12000	COG0189	ligase activity
IX92_12005	COG0189	ligase activity
IX92_12015	COG0733	neurotransmitter:sodium symporter activity
IX92_12030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IX92_12035	COG0514	ATP-dependent DNA helicase (RecQ)
IX92_12040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IX92_12045	COG3706	GGDEF domain
IX92_12045	COG0745	RESPONSE REGULATOR receiver
IX92_12055	COG1477	protein flavinylation
IX92_12060	COG2871	sodium ion transport
IX92_12065	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IX92_12080	COG1805	sodium ion transport
IX92_12085	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IX92_12090	COG0271	Belongs to the BolA IbaG family
IX92_12095	COG2813	Specifically methylates the guanine in position
IX92_12105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IX92_12120	COG1595	DNA-templated transcription, initiation
IX92_12130	COG3248	Nucleoside-binding outer membrane protein
IX92_12135	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IX92_12140	COG0693	protein deglycase activity
IX92_12145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IX92_12150	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IX92_12160	COG0560	Phosphoserine phosphatase
IX92_12170	COG0813	purine-nucleoside phosphorylase activity
IX92_12175	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IX92_12180	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IX92_12195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IX92_12200	COG0084	hydrolase, TatD family'
IX92_12205	COG3022	response to hydroperoxide
IX92_12210	COG1115	amino acid carrier protein
IX92_12225	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IX92_12230	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IX92_12240	COG0583	DNA-binding transcription factor activity
IX92_12245	COG0730	response to heat
IX92_12250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IX92_12255	COG0505	Belongs to the CarA family
IX92_12265	COG0494	nUDIX hydrolase
IX92_12275	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IX92_12280	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IX92_12285	COG0849	cell division
IX92_12290	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IX92_12305	COG0772	Belongs to the SEDS family
IX92_12310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IX92_12315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IX92_12320	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IX92_12325	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IX92_12330	COG0768	penicillin binding
IX92_12335	COG3116	cell division
IX92_12345	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IX92_12350	COG3107	peptidoglycan biosynthetic process
IX92_12360	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IX92_12370	COG2969	positive regulation of protein catabolic process
IX92_12375	COG0625	glutathione transferase activity
IX92_12380	COG2857	Cytochrome c1
IX92_12385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IX92_12390	COG0723	plastoquinol--plastocyanin reductase activity
IX92_12405	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IX92_12410	COG3105	Protein conserved in bacteria
IX92_12415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IX92_12420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IX92_12430	COG0187	DNA topoisomerase II activity
IX92_12435	COG3150	esterase
IX92_12445	COG3151	Protein conserved in bacteria
IX92_12450	COG0494	nUDIX hydrolase
IX92_12455	COG1538	Outer membrane efflux protein
IX92_12465	COG5002	protein histidine kinase activity
IX92_12465	COG2198	Histidine kinase
IX92_12465	COG0784	Response regulator, receiver
IX92_12470	COG5001	Diguanylate cyclase
IX92_12470	COG4251	negative regulation of phosphorylation
IX92_12470	COG3706	GGDEF domain
IX92_12470	COG2203	Gaf domain
IX92_12475	COG1242	4 iron, 4 sulfur cluster binding
IX92_12480	COG0070	glutamate synthase
IX92_12480	COG0067	glutamate synthase
IX92_12480	COG0069	glutamate synthase activity
IX92_12490	COG0070	glutamate synthase
IX92_12490	COG0069	glutamate synthase activity
IX92_12490	COG0067	glutamate synthase
IX92_12495	COG0493	'glutamate synthase
IX92_12520	COG0195	Participates in both transcription termination and antitermination
IX92_12525	COG0779	Required for maturation of 30S ribosomal subunits
IX92_12540	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IX92_12545	COG3153	acetyltransferase
IX92_12570	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IX92_12575	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IX92_12590	COG0513	Belongs to the DEAD box helicase family
IX92_12615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IX92_12620	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IX92_12625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IX92_12630	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IX92_12635	COG1534	Rna-binding protein
IX92_12640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IX92_12645	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IX92_12650	COG2027	D-alanyl-D-alanine carboxypeptidase
IX92_12660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IX92_12665	COG0739	heme binding
IX92_12690	COG0628	permease
IX92_12695	COG2813	Specifically methylates the guanine in position
IX92_12705	COG0747	negative chemotaxis
IX92_12720	COG0444	Belongs to the ABC transporter superfamily
IX92_12725	COG4608	Belongs to the ABC transporter superfamily
IX92_12735	COG2971	BadF BadG BcrA BcrD
IX92_12750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IX92_12755	COG3842	ATPase activity
IX92_12765	COG1840	ABC-type Fe3 transport system, periplasmic component
IX92_12770	COG0004	ammonium transporteR
IX92_12785	COG1049	propionate catabolic process, 2-methylcitrate cycle
IX92_12790	COG1752	Esterase of the alpha-beta hydrolase superfamily
IX92_12795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IX92_12800	COG1643	Atp-dependent helicase
IX92_12810	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IX92_12825	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IX92_12840	COG0842	Transport permease protein
IX92_12845	COG1131	(ABC) transporter
IX92_12850	COG0659	secondary active sulfate transmembrane transporter activity
IX92_12855	COG0288	reversible hydration of carbon dioxide
IX92_12870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IX92_12875	COG0508	dehydrogenase complex catalyzes the overall conversion of
IX92_12880	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IX92_12885	COG2186	Transcriptional regulator
IX92_12895	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IX92_12900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IX92_12910	COG0716	FMN binding
IX92_12915	COG3023	N-Acetylmuramoyl-L-alanine amidase
IX92_12920	COG0157	Belongs to the NadC ModD family
IX92_12925	COG4969	Belongs to the N-Me-Phe pilin family
IX92_12930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IX92_12935	COG1459	type II secretion system
IX92_12945	COG0237	dephospho-CoA kinase activity
IX92_12950	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
IX92_12955	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IX92_12965	COG0336	Belongs to the RNA methyltransferase TrmD family
IX92_12975	COG0228	four-way junction DNA binding
IX92_12980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IX92_12985	COG4137	Cytochrome C assembly protein
IX92_12990	COG4536	flavin adenine dinucleotide binding
IX92_12995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IX92_13000	COG4942	peptidase
IX92_13000	COG1388	LysM domain
IX92_13010	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IX92_13015	COG0585	pseudouridine synthase activity
IX92_13025	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IX92_13030	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IX92_13040	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IX92_13045	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IX92_13050	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IX92_13055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IX92_13060	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IX92_13065	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IX92_13070	COG1610	YqeY-like protein
IX92_13075	COG0358	DNA primase activity
IX92_13080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IX92_13090	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IX92_13095	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IX92_13100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IX92_13120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IX92_13130	COG3610	response to peptide
IX92_13135	COG2966	Psort location CytoplasmicMembrane, score
IX92_13140	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IX92_13145	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IX92_13150	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IX92_13155	COG0142	geranyltranstransferase activity
IX92_13165	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IX92_13170	COG2213	PTS system mannitol-specific
IX92_13170	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX92_13180	COG3722	fumarate hydratase activity
IX92_13185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IX92_13190	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IX92_13195	COG1349	DNA-binding transcription factor activity
IX92_13200	COG0469	pyruvate kinase activity
IX92_13210	COG3706	GGDEF domain
IX92_13220	COG0583	DNA-binding transcription factor activity
IX92_13230	COG0442	prolyl-tRNA aminoacylation
IX92_13235	COG0668	transmembrane transport
IX92_13240	COG0191	fructose-bisphosphate aldolase activity
IX92_13255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IX92_13260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IX92_13270	COG3091	SprT-like family
IX92_13275	COG2356	endonuclease I
IX92_13280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IX92_13285	COG0189	ligase activity
IX92_13295	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IX92_13310	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IX92_13315	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IX92_13320	COG0762	integral membrane protein
IX92_13340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IX92_13345	COG2066	Belongs to the glutaminase family
IX92_13350	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IX92_13360	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IX92_13415	COG0312	modulator of DNA gyrase
IX92_13420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IX92_13425	COG3164	Protein of unknown function
IX92_13430	COG1530	ribonuclease E activity
IX92_13435	COG0424	maF-like protein
IX92_13440	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IX92_13445	COG1792	Involved in formation and maintenance of cell shape
IX92_13450	COG1077	Cell shape determining protein MreB Mrl
IX92_13495	COG1459	type II secretion system
IX92_13500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IX92_13510	COG3267	Type II secretory pathway component ExeA
IX92_13510	COG3409	Peptidoglycan-binding domain 1 protein
IX92_13535	COG2200	EAL domain
IX92_13535	COG2199	diguanylate cyclase activity
IX92_13540	COG0629	single-stranded DNA binding
IX92_13555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IX92_13565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IX92_13570	COG0527	aspartate kinase activity
IX92_13575	COG0312	modulator of DNA gyrase
IX92_13580	COG3028	Belongs to the UPF0307 family
IX92_13585	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IX92_13590	COG1178	ABC-type Fe3 transport system permease component
IX92_13595	COG4143	(ABC) transporter
IX92_13600	COG0163	prenyltransferase activity
IX92_13605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IX92_13620	COG2105	PFAM AIG2 family protein
IX92_13630	COG0729	surface antigen
IX92_13635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IX92_13645	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IX92_13660	COG1136	(ABC) transporter
IX92_13685	COG0432	Pfam Uncharacterised protein family UPF0047
IX92_13690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IX92_13695	COG0305	Participates in initiation and elongation during chromosome replication
IX92_13725	COG2906	2 iron, 2 sulfur cluster binding
IX92_13730	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IX92_13735	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IX92_13740	COG0049	tRNA binding
IX92_13750	COG2168	tRNA wobble position uridine thiolation
IX92_13755	COG2923	Belongs to the DsrF TusC family
IX92_13765	COG2964	Protein conserved in bacteria
IX92_13770	COG0545	Peptidyl-prolyl cis-trans isomerase
IX92_13785	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IX92_13790	COG0330	HflC and HflK could
IX92_13795	COG0330	HflC and HflK could
IX92_13800	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IX92_13815	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IX92_13825	COG0802	atpase or kinase
IX92_13830	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IX92_13885	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IX92_13890	COG1162	GTPase activity
IX92_13895	COG0688	phosphatidylethanolamine metabolic process
IX92_13900	COG0471	metal ion transport
IX92_13900	COG0490	domain, Protein
IX92_13905	COG0840	transmembrane signaling receptor activity
IX92_13915	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IX92_13920	COG4942	peptidase
IX92_13940	COG2816	NAD+ diphosphatase activity
IX92_13945	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
IX92_13950	COG1943	Transposase
IX92_13955	COG1943	Transposase
IX92_13965	COG0085	RNA polymerase activity
IX92_13975	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IX92_13990	COG0250	Participates in transcription elongation, termination and antitermination
IX92_13995	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IX92_14005	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IX92_14030	COG1072	(Pantothenic acid kinase))
IX92_14045	COG0149	triose-phosphate isomerase activity
IX92_14050	COG0534	Mate efflux family protein
IX92_14055	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IX92_14060	COG1575	Belongs to the MenA family. Type 1 subfamily
IX92_14065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IX92_14070	COG1509	lysine 2,3-aminomutase activity
IX92_14080	COG1285	pathogenesis
IX92_14085	COG0205	6-phosphofructokinase activity
IX92_14090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IX92_14095	COG3678	ATP-independent chaperone mediated protein folding
IX92_14100	COG0745	RESPONSE REGULATOR receiver
IX92_14105	COG2205	protein histidine kinase activity
IX92_14110	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IX92_14115	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IX92_14120	COG0180	Tryptophanyl-tRNA synthetase
IX92_14125	COG0546	phosphoglycolate phosphatase activity
IX92_14130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IX92_14135	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IX92_14180	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IX92_14190	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IX92_14190	COG0678	peroxiredoxin activity
IX92_14200	COG0251	oxidation-reduction process
IX92_14205	COG0165	Argininosuccinate lyase
IX92_14205	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IX92_14210	COG0137	argininosuccinate synthase activity
IX92_14220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IX92_14315	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IX92_14320	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IX92_14465	COG3437	response regulator, receiver
IX92_14470	COG2205	protein histidine kinase activity
IX92_14470	COG5002	protein histidine kinase activity
IX92_14470	COG0784	Response regulator, receiver
IX92_14475	COG0735	belongs to the Fur family
IX92_14485	COG0529	Catalyzes the synthesis of activated sulfate
IX92_14490	COG3273	potassium ion transport
IX92_14490	COG0471	metal ion transport
IX92_14505	COG1648	precorrin-2 dehydrogenase activity
IX92_14505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IX92_14510	COG0737	Belongs to the 5'-nucleotidase family
IX92_14520	COG2153	protein acetylation
IX92_14535	COG0545	Peptidyl-prolyl cis-trans isomerase
IX92_14545	COG0203	ribosomal protein L17
IX92_14560	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IX92_14565	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IX92_14575	COG0201	protein transport
IX92_14585	COG1841	ribosomal large subunit assembly
IX92_14600	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IX92_14615	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IX92_14645	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IX92_14650	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IX92_14670	COG0088	Forms part of the polypeptide exit tunnel
IX92_14680	COG0051	transcription antitermination factor activity, RNA binding
IX92_14685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IX92_14690	COG0557	exoribonuclease II activity
IX92_14695	COG0402	S-adenosylhomocysteine deaminase activity
IX92_14700	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IX92_14705	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IX92_14715	COG1047	Peptidyl-prolyl cis-trans
IX92_14730	COG2249	NAD(P)H dehydrogenase (quinone) activity
IX92_14735	COG0488	(ABC) transporter
IX92_14745	COG0429	hydrolase of the alpha beta-hydrolase fold
IX92_14750	COG3089	Belongs to the UPF0270 family
IX92_14755	COG3954	Phosphoribulokinase
IX92_14760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IX92_14780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IX92_14810	COG3210	domain, Protein
IX92_14815	COG3210	domain, Protein
IX92_14835	COG1027	Aspartate ammonia-lyase
IX92_14840	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IX92_14845	COG1288	antiporter activity
IX92_14860	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IX92_14865	COG0540	Belongs to the ATCase OTCase family
IX92_14870	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IX92_14875	COG1438	arginine binding
IX92_14880	COG4232	protein-disulfide reductase activity
IX92_14890	COG2095	MarC family integral membrane protein
IX92_14900	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IX92_14910	COG2205	protein histidine kinase activity
IX92_14910	COG0784	Response regulator, receiver
IX92_14915	COG2814	Major facilitator Superfamily
IX92_14930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IX92_14935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IX92_14940	COG0511	ligase activity, forming carbon-carbon bonds
IX92_14945	COG0439	Biotin carboxylase
IX92_14950	COG2264	protein methyltransferase activity
IX92_14955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IX92_14960	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IX92_14965	COG3706	GGDEF domain
IX92_14970	COG0789	Transcriptional regulator
IX92_14975	COG0138	bifunctional purine biosynthesis protein purh
IX92_14980	COG0151	Belongs to the GarS family
IX92_14995	COG1253	flavin adenine dinucleotide binding
IX92_15000	COG3068	Protein conserved in bacteria
IX92_15005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IX92_15010	COG1573	uracil-dna glycosylase
IX92_15015	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IX92_15020	COG1695	Transcriptional regulator
IX92_15025	COG1045	serine acetyltransferase
IX92_15040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IX92_15045	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IX92_15050	COG1053	succinate dehydrogenase
IX92_15055	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IX92_15085	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IX92_15090	COG1609	Transcriptional regulator
IX92_15095	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IX92_15105	COG0281	malic enzyme
IX92_15115	COG0626	cystathionine gamma-synthase activity
IX92_15120	COG0460	homoserine dehydrogenase
IX92_15120	COG0527	aspartate kinase activity
IX92_15125	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IX92_15135	COG1494	fructose-1,6-bisphosphatase
IX92_15145	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IX92_15160	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IX92_15165	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IX92_15165	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IX92_15170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IX92_15180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IX92_15185	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IX92_15195	COG2076	Multidrug Resistance protein
IX92_15205	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IX92_15210	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_15240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IX92_15255	COG0438	transferase activity, transferring glycosyl groups
IX92_15260	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IX92_15260	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IX92_15265	COG0367	asparagine synthase
IX92_15275	COG0438	transferase activity, transferring glycosyl groups
IX92_15300	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IX92_15320	COG0859	PFAM glycosyl transferase family 9
IX92_15335	COG1519	Transferase
IX92_15360	COG3642	lipopolysaccharide core region biosynthetic process
IX92_15365	COG0859	PFAM glycosyl transferase family 9
IX92_15370	COG0463	Glycosyl transferase, family 2
IX92_15375	COG0859	PFAM glycosyl transferase family 9
IX92_15380	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IX92_15410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IX92_15415	COG1309	transcriptional regulator
IX92_15420	COG1560	Kdo2-lipid A biosynthetic process
IX92_15425	COG1560	Kdo2-lipid A biosynthetic process
IX92_15430	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IX92_15440	COG1561	YicC-like family, N-terminal region
IX92_15445	COG2252	PERMEase
IX92_15455	COG0848	biopolymer transport protein
IX92_15485	COG1595	DNA-templated transcription, initiation
IX92_15500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IX92_15505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IX92_15510	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IX92_15515	COG1218	3'(2'),5'-bisphosphate nucleotidase
IX92_15520	COG0494	nUDIX hydrolase
IX92_15525	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IX92_15525	COG0316	Belongs to the HesB IscA family
IX92_15535	COG0596	Alpha beta hydrolase
IX92_15545	COG2183	response to ionizing radiation
IX92_15555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IX92_15560	COG0745	RESPONSE REGULATOR receiver
IX92_15575	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IX92_15580	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IX92_15585	COG3156	type II secretion system protein K
IX92_15590	COG4795	General secretion pathway protein
IX92_15595	COG2165	general secretion pathway protein
IX92_15600	COG2165	general secretion pathway protein
IX92_15605	COG2165	general secretion pathway protein
IX92_15610	COG1459	type II secretion system
IX92_15615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IX92_15625	COG3031	protein transport across the cell outer membrane
IX92_15630	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IX92_15640	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IX92_15650	COG0456	acetyltransferase
IX92_15655	COG1490	D-aminoacyl-tRNA deacylase activity
IX92_15675	COG0174	glutamine synthetase
IX92_15680	COG3852	Histidine kinase
IX92_15685	COG2204	response regulator
IX92_15695	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IX92_15735	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IX92_15750	COG0408	coproporphyrinogen oxidase activity
IX92_15760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IX92_15765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IX92_15770	COG0551	DNA topoisomerase type I activity
IX92_15775	COG2922	Belongs to the Smg family
IX92_15780	COG0758	DNA mediated transformation
IX92_15795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IX92_15795	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IX92_15800	COG0569	domain protein
IX92_15805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IX92_15815	COG1272	protein, Hemolysin III
IX92_15820	COG4326	sporulation control protein
IX92_15830	COG3084	Protein conserved in bacteria
IX92_15840	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IX92_15845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IX92_15850	COG0204	Acyl-transferase
IX92_15860	COG0606	chelatase, subunit chli
IX92_15870	COG3978	acetolactate synthase activity
IX92_15875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IX92_15880	COG0129	dihydroxy-acid dehydratase activity
IX92_15890	COG0604	alcohol dehydrogenase
IX92_15905	COG0425	Belongs to the sulfur carrier protein TusA family
IX92_15915	COG2119	membrane
IX92_15925	COG0751	glycine-tRNA ligase activity
IX92_15930	COG3977	Valine--pyruvate aminotransferase
IX92_15935	COG0071	Belongs to the small heat shock protein (HSP20) family
IX92_15940	COG0187	DNA topoisomerase II activity
IX92_15945	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IX92_15950	COG0592	DNA-directed DNA polymerase activity
IX92_15970	COG1126	abc transporter atp-binding protein
IX92_15985	COG0706	membrane insertase activity
IX92_15990	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IX92_15995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IX92_16020	COG4608	Belongs to the ABC transporter superfamily
IX92_16025	COG0444	Belongs to the ABC transporter superfamily
IX92_16060	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_16070	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_16075	COG1733	regulation of RNA biosynthetic process
IX92_16095	COG0583	DNA-binding transcription factor activity
IX92_16100	COG1051	belongs to the nudix hydrolase family
IX92_16120	COG0697	spore germination
IX92_16125	COG1846	Transcriptional regulator
IX92_16155	COG1288	antiporter activity
IX92_16160	COG0583	DNA-binding transcription factor activity
IX92_16170	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IX92_16175	COG3960	tartronate-semialdehyde synthase activity
IX92_16180	COG3622	Belongs to the hyi family
IX92_16185	COG2084	Dehydrogenase
IX92_16205	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IX92_16220	COG0559	Belongs to the binding-protein-dependent transport system permease family
IX92_16245	COG0831	urea catabolic process
IX92_16250	COG0832	Belongs to the urease beta subunit family
IX92_16255	COG0804	urea catabolic process
IX92_16260	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
IX92_16310	COG0840	transmembrane signaling receptor activity
IX92_16315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX92_16330	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IX92_16340	COG4145	pantothenate transmembrane transporter activity
IX92_16345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IX92_16350	COG0800	Aldolase
IX92_16360	COG2706	6-phosphogluconolactonase activity
IX92_16370	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IX92_16375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IX92_16380	COG1845	cytochrome c oxidase, subunit III
IX92_16385	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IX92_16390	COG0109	protoheme IX farnesyltransferase activity
IX92_16425	COG0583	DNA-binding transcription factor activity
IX92_16450	COG3214	Protein conserved in bacteria
IX92_16455	COG0596	Alpha beta hydrolase
IX92_16470	COG2252	PERMEase
IX92_16490	COG4266	Belongs to the allantoicase family
IX92_16505	COG0840	transmembrane signaling receptor activity
IX92_16515	COG1522	sequence-specific DNA binding
IX92_16525	COG5002	protein histidine kinase activity
IX92_16525	COG0784	Response regulator, receiver
IX92_16525	COG2205	protein histidine kinase activity
IX92_16530	COG2226	methyltransferase
IX92_16535	COG0402	S-adenosylhomocysteine deaminase activity
IX92_16545	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IX92_16555	COG2186	Transcriptional regulator
IX92_16580	COG3795	YCII-related domain
IX92_16610	COG0402	S-adenosylhomocysteine deaminase activity
IX92_16615	COG1404	Belongs to the peptidase S8 family
IX92_16620	COG1335	isochorismatase
IX92_16625	COG2207	Transcriptional regulator
IX92_16670	COG2909	trisaccharide binding
IX92_16675	COG0058	SHG alpha-glucan phosphorylase activity
IX92_16680	COG1640	4-alpha-glucanotransferase
IX92_16685	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IX92_16700	COG1619	proteins homologs of microcin C7 resistance protein MccF
IX92_16740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IX92_16755	COG2249	NAD(P)H dehydrogenase (quinone) activity
IX92_16765	COG0583	DNA-binding transcription factor activity
IX92_16775	COG0300	oxidoreductase activity
IX92_16825	COG0561	phosphatase activity
IX92_16840	COG0024	Methionine aminopeptidase
IX92_16870	COG1733	regulation of RNA biosynthetic process
IX92_16930	COG0583	DNA-binding transcription factor activity
IX92_16965	COG1917	Cupin 2, conserved barrel domain protein
IX92_16965	COG2207	Transcriptional regulator
IX92_16970	COG1280	lysine exporter protein (LysE YggA)
IX92_16995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IX92_17000	COG0383	alpha-mannosidase activity
IX92_17005	COG0366	Alpha amylase catalytic
IX92_17010	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IX92_17010	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IX92_17010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX92_17015	COG4968	Prepilin-type N-terminal cleavage methylation domain
IX92_17025	COG2814	Major facilitator Superfamily
IX92_17030	COG1120	ATPase activity
IX92_17045	COG4264	IucA IucC family
IX92_17070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IX92_17080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IX92_17090	COG0662	Cupin 2, conserved barrel domain protein
IX92_17095	COG1960	acyl-CoA dehydrogenase activity
IX92_17100	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IX92_17105	COG2076	Multidrug Resistance protein
IX92_17110	COG2076	Multidrug Resistance protein
IX92_17115	COG0590	tRNA wobble adenosine to inosine editing
IX92_17130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IX92_17170	COG3448	diguanylate cyclase activity
IX92_17170	COG4175	Glycine betaine
IX92_17175	COG4176	ABC-type proline glycine betaine transport system permease component
IX92_17195	COG2095	MarC family integral membrane protein
IX92_17205	COG0534	Mate efflux family protein
IX92_17215	COG0583	DNA-binding transcription factor activity
IX92_17240	COG4964	Belongs to the GSP D family
IX92_17250	COG2894	cell division
IX92_17305	COG1477	protein flavinylation
IX92_17325	COG4221	oxidoreductase activity
IX92_17330	COG0840	transmembrane signaling receptor activity
IX92_17335	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IX92_17340	COG0573	inorganic phosphate transmembrane transporter activity
IX92_17345	COG0581	inorganic phosphate transmembrane transporter activity
IX92_17365	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IX92_17370	COG1162	GTPase activity
IX92_17390	COG1122	ATPase activity
IX92_17395	COG4720	Psort location CytoplasmicMembrane, score
IX92_17400	COG0363	glucosamine-6-phosphate deaminase activity
IX92_17415	COG0454	-acetyltransferase
IX92_17420	COG0840	transmembrane signaling receptor activity
IX92_17450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IX92_17455	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IX92_17460	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
IX92_17470	COG1522	sequence-specific DNA binding
IX92_17500	COG3608	succinylglutamate desuccinylase aspartoacylase
IX92_17505	COG1288	antiporter activity
IX92_17520	COG0745	RESPONSE REGULATOR receiver
IX92_17545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX92_17565	COG0583	DNA-binding transcription factor activity
IX92_17570	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IX92_17575	COG1151	hydroxylamine reductase activity
IX92_17585	COG3706	GGDEF domain
IX92_17590	COG0583	DNA-binding transcription factor activity
IX92_17610	COG3604	Transcriptional regulator
IX92_17635	COG0415	Belongs to the DNA photolyase family
IX92_17640	COG3046	protein related to deoxyribodipyrimidine photolyase
IX92_17650	COG2329	Antibiotic biosynthesis monooxygenase
IX92_17655	COG3304	Inner membrane component domain
IX92_17665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX92_17675	COG0583	DNA-binding transcription factor activity
IX92_17680	COG1234	tRNA 3'-trailer cleavage
IX92_17710	COG0004	ammonium transporteR
IX92_17715	COG3437	response regulator, receiver
IX92_17720	COG3383	formate dehydrogenase (NAD+) activity
IX92_17725	COG0446	pyridine nucleotide-disulphide oxidoreductase
IX92_17730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IX92_17735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IX92_17760	COG0739	heme binding
IX92_17765	COG3047	cAMP biosynthetic process
IX92_17790	COG0300	oxidoreductase activity
IX92_17795	COG5553	Cysteine dioxygenase type I
IX92_17810	COG0673	inositol 2-dehydrogenase activity
IX92_17815	COG0488	(ABC) transporter
IX92_17845	COG4191	Histidine kinase
IX92_17845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX92_17850	COG1320	monovalent cation:proton antiporter activity
IX92_17855	COG2212	antiporter activity
IX92_17870	COG1006	Multisubunit Na H antiporter MnhC subunit
IX92_17875	COG2111	Na H antiporter
IX92_17875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IX92_17885	COG0589	response to stress
IX92_17890	COG1132	(ABC) transporter
IX92_17900	COG0583	DNA-binding transcription factor activity
IX92_17915	COG1690	Belongs to the RtcB family
IX92_17920	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IX92_17940	COG3541	Predicted nucleotidyltransferase
IX92_17945	COG1690	Belongs to the RtcB family
IX92_17965	COG4650	regulator
IX92_17980	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IX92_17990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IX92_18005	COG4580	involved in the transport of maltose and maltodextrins
IX92_18015	COG0840	transmembrane signaling receptor activity
IX92_18050	COG0840	transmembrane signaling receptor activity
IX92_18080	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IX92_18090	COG0415	Belongs to the DNA photolyase family
IX92_18110	COG0697	spore germination
IX92_18135	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IX92_18135	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IX92_18145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IX92_18145	COG2207	Transcriptional regulator
IX92_18150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IX92_18170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IX92_18180	COG1522	sequence-specific DNA binding
IX92_18205	COG1357	PFAM Pentapeptide repeats (8 copies)
IX92_18210	COG1294	oxidase, subunit
IX92_18215	COG1271	oxidase subunit
IX92_18220	COG1805	sodium ion transport
IX92_18240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IX92_18265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX92_18275	COG1309	transcriptional regulator
IX92_18295	COG0745	RESPONSE REGULATOR receiver
IX92_18300	COG5002	protein histidine kinase activity
IX92_18335	COG0842	Transport permease protein
IX92_18340	COG1131	(ABC) transporter
IX92_18380	COG0346	lactoylglutathione lyase activity
IX92_18385	COG0625	glutathione transferase activity
IX92_18390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IX92_18400	COG0366	Alpha amylase catalytic
IX92_18420	COG2084	Dehydrogenase
IX92_18430	COG0625	glutathione transferase activity
IX92_18435	COG2130	NADP-dependent
IX92_18440	COG1309	transcriptional regulator
IX92_18445	COG3706	GGDEF domain
IX92_18465	COG0513	Belongs to the DEAD box helicase family
IX92_18475	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IX92_18500	COG0745	RESPONSE REGULATOR receiver
IX92_18505	COG4191	Histidine kinase
IX92_18515	COG0573	inorganic phosphate transmembrane transporter activity
IX92_18525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IX92_18545	COG0395	ABC-type sugar transport system, permease component
IX92_18550	COG1554	hydrolase, family 65, central catalytic
IX92_18555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IX92_18570	COG1621	beta-fructofuranosidase activity
IX92_18580	COG0110	maltose O-acetyltransferase activity
IX92_18605	COG0251	oxidation-reduction process
IX92_18620	COG2356	endonuclease I
IX92_18645	COG0564	pseudouridine synthase activity
IX92_18670	COG0583	DNA-binding transcription factor activity
IX92_18675	COG2814	Major facilitator Superfamily
IX92_18700	COG0840	transmembrane signaling receptor activity
IX92_18705	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IX92_18715	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IX92_18725	COG0579	oxidoreductase
IX92_18755	COG1012	belongs to the aldehyde dehydrogenase family
IX92_18760	COG3284	Transcriptional regulator
IX92_18780	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IX92_18785	COG0363	glucosamine-6-phosphate deaminase activity
IX92_18790	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IX92_18795	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IX92_18815	COG2271	Major facilitator Superfamily
IX92_18820	COG3851	Histidine kinase
IX92_18825	COG2197	response regulator
IX92_18850	COG3217	Mosc domain protein beta barrel domain protein
IX92_18850	COG0633	Ferredoxin
IX92_18850	COG0633	Ferredoxin
IX92_18850	COG3217	Mosc domain protein beta barrel domain protein
IX92_18860	COG1349	DNA-binding transcription factor activity
IX92_18885	COG2354	Protein conserved in bacteria
IX92_18895	COG0366	Alpha amylase catalytic
IX92_18930	COG0840	transmembrane signaling receptor activity
IX92_18935	COG1366	Belongs to the anti-sigma-factor antagonist family
IX92_18945	COG2172	sigma factor antagonist activity
IX92_18955	COG3437	response regulator, receiver
IX92_18955	COG3850	Histidine kinase
IX92_18955	COG4999	Histidine kinase
IX92_18955	COG2205	protein histidine kinase activity
IX92_18960	COG3437	response regulator, receiver
IX92_18975	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IX92_18975	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IX92_18985	COG0516	GMP reductase activity
IX92_18990	COG0582	viral genome integration into host DNA
IX92_19140	COG4695	Portal protein
IX92_19180	COG4386	tail sheath protein
IX92_19210	COG3646	Phage regulatory protein
IX92_19235	COG0516	GMP reductase activity
IX92_19260	COG1309	transcriptional regulator
IX92_19285	COG3448	diguanylate cyclase activity
IX92_19285	COG4175	Glycine betaine
IX92_19305	COG1304	FMN binding
IX92_19310	COG1620	l-lactate permease
IX92_19315	COG0583	DNA-binding transcription factor activity
IX92_19335	COG4172	Belongs to the ABC transporter superfamily
IX92_19345	COG1067	ATP-dependent peptidase activity
IX92_19350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IX92_19355	COG0840	transmembrane signaling receptor activity
IX92_19370	COG4166	transmembrane transport
IX92_19375	COG4174	ABC transporter (Permease)
IX92_19380	COG4239	(ABC) transporter, permease
IX92_19385	COG4172	Belongs to the ABC transporter superfamily
IX92_19395	COG0745	RESPONSE REGULATOR receiver
IX92_19395	COG3706	GGDEF domain
IX92_19435	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IX92_19440	COG4605	iron ion homeostasis
IX92_19445	COG4604	ABC transporter, ATP-binding protein
IX92_19450	COG2759	Belongs to the formate--tetrahydrofolate ligase family
IX92_19465	COG0004	ammonium transporteR
IX92_19470	COG4607	ABC-type enterochelin transport system periplasmic component
IX92_19475	COG4206	TonB-dependent receptor
IX92_19495	COG2271	Major facilitator Superfamily
IX92_19505	COG0840	transmembrane signaling receptor activity
IX92_19510	COG2203	Gaf domain
IX92_19510	COG2199	diguanylate cyclase activity
IX92_19520	COG0739	heme binding
IX92_19555	COG3501	Rhs element vgr protein
IX92_19580	COG2815	serine threonine protein kinase
IX92_19580	COG0515	serine threonine protein kinase
IX92_19615	COG1522	sequence-specific DNA binding
IX92_19655	COG3250	beta-galactosidase activity
IX92_19660	COG2211	Major facilitator Superfamily
IX92_19675	COG1609	Transcriptional regulator
IX92_19680	COG1309	transcriptional regulator
IX92_19685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX92_19690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX92_19705	COG0183	Belongs to the thiolase family
IX92_19720	COG1794	racemase activity, acting on amino acids and derivatives
IX92_19725	COG2814	Major facilitator Superfamily
IX92_19730	COG3240	lipase activity
IX92_19735	COG4412	M6 family metalloprotease domain protein
IX92_19735	COG3291	Pkd domain containing protein
IX92_19780	COG1328	CTP reductase activity
IX92_19785	COG0602	queuosine metabolic process
IX92_19795	COG0189	ligase activity
IX92_19795	COG4067	protein conserved in archaea
IX92_19805	COG0545	Peptidyl-prolyl cis-trans isomerase
IX92_19825	COG0247	lactate metabolic process
IX92_19830	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
IX92_19835	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IX92_19840	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IX92_19845	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IX92_19870	COG2827	Endonuclease containing a URI domain
IX92_19885	COG5002	protein histidine kinase activity
IX92_19885	COG0784	Response regulator, receiver
IX92_19910	COG1289	transmembrane transporter activity
IX92_19915	COG0210	DNA helicase
IX92_19935	COG0484	heat shock protein binding
IX92_19945	COG5001	Diguanylate cyclase
IX92_19945	COG3300	MHYT domain
IX92_19950	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IX92_19960	COG4181	ATPase activity
IX92_19965	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IX92_19970	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IX92_19975	COG1984	allophanate hydrolase subunit 2
IX92_19985	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IX92_19990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IX92_19995	COG3005	denitrification pathway
IX92_20005	COG0243	molybdopterin cofactor binding
IX92_20015	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IX92_20020	COG3850	Histidine kinase
IX92_20025	COG2197	response regulator
IX92_20030	COG3069	C4-dicarboxylate transmembrane transporter activity
IX92_20050	COG3038	cytochrome b561
IX92_20055	COG2353	YceI-like domain
IX92_20060	COG2116	formate transmembrane transporter activity
IX92_20065	COG0583	DNA-binding transcription factor activity
IX92_20075	COG3593	DNA synthesis involved in DNA repair
IX92_20080	COG0737	Belongs to the 5'-nucleotidase family
IX92_20115	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IX92_20145	COG0582	viral genome integration into host DNA
IX92_20170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IX92_20225	COG3772	lysozyme
IX92_20365	COG4783	chaperone-mediated protein folding
IX92_20370	COG2050	protein possibly involved in aromatic compounds catabolism
IX92_20380	COG4533	DNA binding
IX92_20395	COG0583	DNA-binding transcription factor activity
IX92_20400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IX92_20400	COG1042	CoA-binding domain protein
IX92_20400	COG0045	succinate-CoA ligase (ADP-forming) activity
IX92_20405	COG3266	domain, Protein
IX92_20410	COG1181	Belongs to the D-alanine--D-alanine ligase family
IX92_20425	COG0023	Translation Initiation Factor
IX92_20550	COG0745	RESPONSE REGULATOR receiver
IX92_20560	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IX92_20565	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IX92_20580	COG3706	GGDEF domain
IX92_20585	COG4251	negative regulation of phosphorylation
IX92_20585	COG2203	Gaf domain
IX92_20585	COG5001	Diguanylate cyclase
IX92_20585	COG3706	GGDEF domain
IX92_20595	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IX92_20600	COG4149	molybdate abc transporter
IX92_20605	COG0725	ABC transporter, periplasmic molybdate-binding protein
IX92_20625	COG1609	Transcriptional regulator
IX92_20635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX92_20635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX92_20640	COG1105	Belongs to the carbohydrate kinase PfkB family
IX92_20645	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IX92_20645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IX92_20645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IX92_20650	COG3706	GGDEF domain
IX92_20655	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IX92_20660	COG2207	Transcriptional regulator
IX92_20665	COG1979	alcohol dehydrogenase
IX92_20680	COG2205	protein histidine kinase activity
IX92_20680	COG2198	Histidine kinase
IX92_20680	COG0784	Response regulator, receiver
IX92_20685	COG1879	ABC-type sugar transport system periplasmic component
IX92_20690	COG1803	Methylglyoxal synthase
IX92_20695	COG2188	Transcriptional regulator
IX92_20705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IX92_20705	COG1263	PTS System
IX92_20710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IX92_20715	COG0800	Aldolase
IX92_20725	COG0546	phosphoglycolate phosphatase activity
IX92_20740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IX92_20745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IX92_20755	COG0583	DNA-binding transcription factor activity
IX92_20760	COG3048	D-serine ammonia-lyase activity
IX92_20770	COG0346	lactoylglutathione lyase activity
IX92_20785	COG0456	acetyltransferase
IX92_20785	COG1214	PFAM Peptidase M22, glycoprotease
IX92_20815	COG0513	Belongs to the DEAD box helicase family
IX92_20825	COG0814	amino acid
IX92_20830	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IX92_20830	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IX92_20840	COG0513	Belongs to the DEAD box helicase family
IX92_20855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IX92_20865	COG2897	thiosulfate sulfurtransferase activity
IX92_20890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IX92_20895	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IX92_20900	COG1522	sequence-specific DNA binding
IX92_20915	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IX92_20920	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IX92_20925	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IX92_20930	COG1473	amidohydrolase
IX92_20940	COG1522	sequence-specific DNA binding
IX92_20955	COG2199	diguanylate cyclase activity
IX92_20975	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IX92_20985	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IX92_20990	COG0523	cobalamin synthesis protein
IX92_20995	COG0038	chloride channel
IX92_21005	COG0156	8-amino-7-oxononanoate synthase activity
IX92_21010	COG0784	Response regulator, receiver
IX92_21010	COG2205	protein histidine kinase activity
IX92_21015	COG0419	ATPase involved in DNA repair
IX92_21025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IX92_21030	COG3118	belongs to the thioredoxin family
IX92_21050	COG2146	nitrite reductase [NAD(P)H] activity
IX92_21055	COG2146	nitrite reductase [NAD(P)H] activity
IX92_21055	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IX92_21060	COG1116	anion transmembrane transporter activity
IX92_21065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IX92_21070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IX92_21070	COG1116	anion transmembrane transporter activity
IX92_21080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IX92_21085	COG1648	precorrin-2 dehydrogenase activity
IX92_21085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IX92_21090	COG0243	molybdopterin cofactor binding
IX92_21130	COG2315	Protein conserved in bacteria
IX92_21140	COG2203	Gaf domain
IX92_21140	COG2199	diguanylate cyclase activity
IX92_21165	COG3706	GGDEF domain
IX92_21185	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
IX92_21190	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_21200	COG1024	Enoyl-CoA hydratase
IX92_21205	COG1024	Enoyl-CoA hydratase
IX92_21210	COG1960	acyl-CoA dehydrogenase activity
IX92_21220	COG0183	Belongs to the thiolase family
IX92_21230	COG1960	acyl-CoA dehydrogenase activity
IX92_21235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IX92_21240	COG1024	Enoyl-CoA hydratase
IX92_21270	COG2259	Doxx family
IX92_21275	COG1741	Belongs to the pirin family
IX92_21290	COG1115	amino acid carrier protein
IX92_21295	COG0583	DNA-binding transcription factor activity
IX92_21300	COG2910	NAD(P)H-binding
IX92_21320	COG5001	Diguanylate cyclase
IX92_21320	COG1716	ATPase activity
IX92_21390	COG0583	DNA-binding transcription factor activity
IX92_21395	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IX92_21400	COG5001	Diguanylate cyclase
IX92_21400	COG3300	MHYT domain
IX92_21425	COG0789	Transcriptional regulator
IX92_21435	COG2176	DNA-directed DNA polymerase activity
IX92_21440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IX92_21445	COG1846	Transcriptional regulator
IX92_21450	COG3706	GGDEF domain
IX92_21475	COG2814	Major facilitator Superfamily
IX92_21480	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IX92_21485	COG0714	Associated with various cellular activities
IX92_21490	COG0494	nUDIX hydrolase
IX92_21500	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_21515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IX92_21520	COG0835	chemotaxis
IX92_21520	COG0784	Response regulator, receiver
IX92_21525	COG3706	GGDEF domain
IX92_21550	COG1760	l-serine dehydratase
IX92_21555	COG0583	DNA-binding transcription factor activity
IX92_21560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IX92_21565	COG2866	Carboxypeptidase
IX92_21595	COG3842	ATPase activity
IX92_21605	COG1840	ABC-type Fe3 transport system, periplasmic component
IX92_21610	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IX92_21635	COG2378	regulation of single-species biofilm formation
IX92_21645	COG1011	Hydrolase
IX92_21655	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IX92_21660	COG1454	alcohol dehydrogenase
IX92_21705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IX92_21710	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IX92_21755	COG3186	Phenylalanine-4-hydroxylase
IX92_21760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IX92_21765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IX92_21785	COG0784	Response regulator, receiver
IX92_21785	COG2205	protein histidine kinase activity
IX92_21790	COG2205	protein histidine kinase activity
IX92_21790	COG0784	Response regulator, receiver
IX92_21795	COG0612	Peptidase, M16
IX92_21805	COG0798	PFAM Bile acid sodium symporter
IX92_21820	COG2195	Cleaves the N-terminal amino acid of tripeptides
IX92_21830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IX92_21860	COG1063	alcohol dehydrogenase
IX92_21865	COG0156	8-amino-7-oxononanoate synthase activity
IX92_21870	COG2199	diguanylate cyclase activity
IX92_21870	COG2200	EAL domain
IX92_21870	COG2202	Pas domain
IX92_21890	COG0346	lactoylglutathione lyase activity
IX92_21900	COG4452	Inner membrane protein CreD
IX92_21905	COG2205	protein histidine kinase activity
IX92_21910	COG0745	RESPONSE REGULATOR receiver
IX92_21925	COG0745	RESPONSE REGULATOR receiver
IX92_21930	COG2205	protein histidine kinase activity
IX92_21945	COG0667	Aldo Keto reductase
IX92_21950	COG0583	DNA-binding transcription factor activity
IX92_21965	COG0714	Associated with various cellular activities
IX92_21980	COG2304	oxidoreductase activity
IX92_21985	COG2304	oxidoreductase activity
IX92_22005	COG0110	maltose O-acetyltransferase activity
IX92_22010	COG1765	OsmC-like protein
IX92_22015	COG0673	inositol 2-dehydrogenase activity
IX92_22035	COG0531	amino acid
IX92_22055	COG2205	protein histidine kinase activity
IX92_22060	COG0745	RESPONSE REGULATOR receiver
IX92_22085	COG1566	PFAM secretion protein HlyD family protein
IX92_22090	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IX92_22095	COG0402	S-adenosylhomocysteine deaminase activity
IX92_22100	COG0861	Integral membrane protein TerC family
IX92_22110	COG0784	Response regulator, receiver
IX92_22110	COG2205	protein histidine kinase activity
IX92_22110	COG5002	protein histidine kinase activity
IX92_22150	COG4533	DNA binding
IX92_22165	COG1175	transmembrane transport
IX92_22175	COG3842	ATPase activity
IX92_22180	COG2096	Adenosyltransferase
IX92_22185	COG0748	coenzyme F420 binding
IX92_22190	COG3721	Heme iron utilization protein
IX92_22200	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IX92_22205	COG0811	peptide transport
IX92_22210	COG0848	biopolymer transport protein
IX92_22220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IX92_22225	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IX92_22230	COG2814	Major facilitator Superfamily
IX92_22240	COG0739	heme binding
IX92_22255	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IX92_22265	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
IX92_22275	COG0513	Belongs to the DEAD box helicase family
IX92_22285	COG4191	Histidine kinase
IX92_22285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX92_22290	COG3437	response regulator, receiver
IX92_22290	COG0784	Response regulator, receiver
IX92_22295	COG1609	Transcriptional regulator
IX92_22300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IX92_22305	COG1879	ABC-type sugar transport system periplasmic component
IX92_22310	COG1172	Belongs to the binding-protein-dependent transport system permease family
IX92_22315	COG1129	ABC transporter
IX92_22320	COG1869	D-ribose catabolic process
IX92_22330	COG3469	chitinase activity
IX92_22345	COG0004	ammonium transporteR
IX92_22370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IX92_22390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IX92_22395	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IX92_22425	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
IX92_22430	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IX92_22435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IX92_22440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IX92_22460	COG1609	Transcriptional regulator
IX92_22465	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IX92_22470	COG3265	gluconokinase activity
IX92_22475	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IX92_22485	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IX92_22530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IX92_22540	COG0668	transmembrane transport
IX92_22560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IX92_22600	COG3118	belongs to the thioredoxin family
IX92_22605	COG4232	protein-disulfide reductase activity
IX92_22620	COG1280	lysine exporter protein (LysE YggA)
IX92_22650	COG0443	Heat shock 70 kDa protein
IX92_22655	COG0583	DNA-binding transcription factor activity
IX92_22665	COG4948	Mandelate Racemase Muconate Lactonizing
IX92_22670	COG1396	sequence-specific DNA binding
IX92_22685	COG3706	GGDEF domain
IX92_22695	COG0642	Histidine kinase
IX92_22700	COG0745	RESPONSE REGULATOR receiver
IX92_22715	COG2130	NADP-dependent
IX92_22730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IX92_22760	COG0534	Mate efflux family protein
IX92_22765	COG0444	Belongs to the ABC transporter superfamily
IX92_22770	COG4608	Belongs to the ABC transporter superfamily
IX92_22775	COG0747	negative chemotaxis
IX92_22795	COG0366	Alpha amylase catalytic
IX92_22825	COG3279	Response regulator of the LytR AlgR family
IX92_22830	COG3275	phosphorelay sensor kinase activity
IX92_22845	COG4591	ABC-type transport system involved in lipoprotein release permease component
IX92_22850	COG1136	(ABC) transporter
IX92_22880	COG3530	Putative quorum-sensing-regulated virulence factor
IX92_22895	COG1686	Belongs to the peptidase S11 family
IX92_22910	COG3036	rescue of stalled ribosome
IX92_22915	COG1278	Cold shock
IX92_22930	COG1017	nitric oxide dioxygenase activity
IX92_22930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IX92_22935	COG3604	Transcriptional regulator
IX92_22945	COG0546	phosphoglycolate phosphatase activity
IX92_22950	COG2249	NAD(P)H dehydrogenase (quinone) activity
IX92_22960	COG0534	Mate efflux family protein
IX92_22970	COG0697	spore germination
IX92_22985	COG2814	Major facilitator Superfamily
IX92_22990	COG0583	DNA-binding transcription factor activity
IX92_22995	COG5001	Diguanylate cyclase
IX92_23045	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
IX92_23055	COG0438	transferase activity, transferring glycosyl groups
IX92_23055	COG0297	glycogen (starch) synthase activity
IX92_23065	COG1045	serine acetyltransferase
IX92_23080	COG0438	transferase activity, transferring glycosyl groups
IX92_23085	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IX92_23090	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IX92_23095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IX92_23100	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IX92_23110	COG2203	Gaf domain
IX92_23110	COG5001	Diguanylate cyclase
IX92_23110	COG3706	GGDEF domain
IX92_23110	COG4251	negative regulation of phosphorylation
IX92_23115	COG4989	oxidoreductase activity
IX92_23125	COG0366	Alpha amylase catalytic
IX92_23135	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IX92_23140	COG1126	abc transporter atp-binding protein
IX92_23145	COG0765	amino acid transport
IX92_23150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX92_23155	COG0765	amino acid transport
IX92_23160	COG0109	protoheme IX farnesyltransferase activity
IX92_23190	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
IX92_23195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IX92_23200	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IX92_23210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IX92_23250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IX92_23275	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX92_23290	COG1741	Belongs to the pirin family
IX92_23300	COG2814	Major facilitator Superfamily
IX92_23305	COG1686	Belongs to the peptidase S11 family
IX92_23310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IX92_23350	COG1253	flavin adenine dinucleotide binding
IX92_23390	COG1280	lysine exporter protein (LysE YggA)
IX92_23395	COG0583	DNA-binding transcription factor activity
IX92_23450	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IX92_23460	COG0523	cobalamin synthesis protein
IX92_23465	COG2988	succinylglutamate desuccinylase activity
IX92_23510	COG1846	Transcriptional regulator
IX92_23520	COG1280	lysine exporter protein (LysE YggA)
IX92_23535	COG1176	ABC-type spermidine putrescine transport system, permease component I
IX92_23540	COG3842	ATPase activity
IX92_23545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IX92_23550	COG2423	ornithine cyclodeaminase activity
IX92_23565	COG3938	Belongs to the proline racemase family
IX92_23575	COG2186	Transcriptional regulator
IX92_23590	COG0601	transmembrane transport
IX92_23595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IX92_23610	COG0006	proline dipeptidase activity
IX92_23645	COG3568	Endonuclease Exonuclease Phosphatase
IX92_23650	COG3291	Pkd domain containing protein
IX92_23655	COG0513	Belongs to the DEAD box helicase family
IX92_23665	COG1388	LysM domain
IX92_23665	COG1376	ErfK ybiS ycfS ynhG family protein
IX92_23670	COG0415	Belongs to the DNA photolyase family
IX92_23675	COG0789	Transcriptional regulator
IX92_23680	COG3272	Protein of unknown function (DUF1722)
IX92_23685	COG0813	purine-nucleoside phosphorylase activity
IX92_23700	COG3706	GGDEF domain
IX92_23715	COG1566	PFAM secretion protein HlyD family protein
IX92_23720	COG0786	glutamate:sodium symporter activity
IX92_23730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IX92_23745	COG0583	DNA-binding transcription factor activity
IX92_23755	COG1132	(ABC) transporter
IX92_23800	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IX92_23810	COG0259	pyridoxamine-phosphate oxidase activity
IX92_23840	COG3033	Beta-eliminating lyase
IX92_23845	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IX92_23850	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IX92_23855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IX92_23865	COG1999	signal sequence binding
IX92_23880	COG1671	Belongs to the UPF0178 family
IX92_23885	COG0393	Putative heavy-metal-binding
IX92_23890	COG0583	DNA-binding transcription factor activity
IX92_23895	COG2814	Major facilitator Superfamily
IX92_23915	COG0584	glycerophosphoryl diester phosphodiesterase
IX92_23930	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IX92_23945	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_23950	COG0583	DNA-binding transcription factor activity
IX92_23970	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IX92_24120	COG1301	dicarboxylic acid transport
IX92_24130	COG1404	Belongs to the peptidase S8 family
IX92_24140	COG2207	Transcriptional regulator
IX92_24155	COG0700	Nucleoside recognition
IX92_24160	COG3366	ferrous iron transmembrane transporter activity
IX92_24165	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IX92_24180	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IX92_24195	COG0784	Response regulator, receiver
IX92_24195	COG5002	protein histidine kinase activity
IX92_24195	COG2198	Histidine kinase
IX92_24200	COG0745	RESPONSE REGULATOR receiver
IX92_24205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX92_24210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX92_24215	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IX92_24240	COG0745	RESPONSE REGULATOR receiver
IX92_24245	COG2205	protein histidine kinase activity
IX92_24250	COG0471	metal ion transport
IX92_24290	COG1595	DNA-templated transcription, initiation
IX92_24305	COG0697	spore germination
IX92_24310	COG0251	oxidation-reduction process
IX92_24315	COG0697	spore germination
IX92_24325	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IX92_24325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IX92_24360	COG0583	DNA-binding transcription factor activity
IX92_24380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IX92_24390	COG1175	transmembrane transport
IX92_24405	COG1940	carbohydrate kinase activity
IX92_24415	COG0438	transferase activity, transferring glycosyl groups
IX92_24425	COG0671	phosphoesterase, PA-phosphatase related
IX92_24435	COG2207	Transcriptional regulator
IX92_24435	COG3708	Transcriptional regulator
IX92_24455	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IX92_24460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IX92_24465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IX92_24470	COG1116	anion transmembrane transporter activity
IX92_24475	COG0351	phosphomethylpyrimidine kinase
IX92_24480	COG0656	L-ascorbic acid biosynthetic process
IX92_24500	COG0583	DNA-binding transcription factor activity
IX92_24520	COG0840	transmembrane signaling receptor activity
IX92_24525	COG0768	penicillin binding
IX92_24530	COG2723	6-phospho-beta-galactosidase activity
IX92_24540	COG0589	response to stress
IX92_24545	COG3842	ATPase activity
IX92_24550	COG0546	phosphoglycolate phosphatase activity
IX92_24570	COG1175	transmembrane transport
IX92_24575	COG0583	DNA-binding transcription factor activity
IX92_24635	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IX92_24655	COG3706	GGDEF domain
IX92_24655	COG0745	RESPONSE REGULATOR receiver
IX92_24680	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IX92_24685	COG0840	transmembrane signaling receptor activity
IX92_24690	COG0835	chemotaxis
IX92_24705	COG0745	RESPONSE REGULATOR receiver
IX92_24715	COG0840	transmembrane signaling receptor activity
IX92_24720	COG1444	tRNA N-acetyltransferase activity
IX92_25360	COG2304	oxidoreductase activity
IX92_25370	COG1595	DNA-templated transcription, initiation
IX92_25525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IX92_25690	COG1475	DNA binding
IX92_25715	COG2916	Histone family protein nucleoid-structuring protein H-NS
IX92_25725	COG5001	Diguanylate cyclase
IX92_25805	COG0210	DNA helicase
IX92_26160	COG2205	protein histidine kinase activity
IX92_26165	COG0745	RESPONSE REGULATOR receiver
IX92_26310	COG2200	EAL domain
IX92_26405	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
IX92_26460	COG3070	regulator of competence-specific genes
IX92_26570	COG1598	PFAM Uncharacterised protein family UPF0150
IX92_26650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IX92_26655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IX92_26715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IX92_26815	COG4591	ABC-type transport system involved in lipoprotein release permease component
IX92_26820	COG1136	(ABC) transporter
IX92_26995	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_27030	COG1716	ATPase activity
IX92_27030	COG5001	Diguanylate cyclase
IX92_27135	COG3437	response regulator, receiver
IX92_27145	COG1192	Involved in chromosome partitioning
IX92_27155	COG2814	Major facilitator Superfamily
IX92_27170	COG3033	Beta-eliminating lyase
IX92_27205	COG0745	RESPONSE REGULATOR receiver
IX92_27215	COG4191	Histidine kinase
IX92_27220	COG5001	Diguanylate cyclase
IX92_27220	COG3300	MHYT domain
IX92_27235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX92_27235	COG4191	Histidine kinase
IX92_27285	COG0814	amino acid
IX92_27305	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_27310	COG0583	DNA-binding transcription factor activity
IX92_27320	COG3527	Alpha-acetolactate decarboxylase
IX92_27330	COG0745	RESPONSE REGULATOR receiver
IX92_27335	COG2205	protein histidine kinase activity
IX92_27430	COG0671	phosphoesterase, PA-phosphatase related
IX92_27445	COG0113	porphobilinogen synthase activity
IX92_27450	COG0183	Belongs to the thiolase family
IX92_27480	COG0604	alcohol dehydrogenase
IX92_27490	COG0702	epimerase
IX92_27510	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IX92_27520	COG0583	DNA-binding transcription factor activity
IX92_27525	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_27640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IX92_27650	COG2084	Dehydrogenase
IX92_27675	COG4774	siderophore transport
IX92_27735	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IX92_27735	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IX92_27740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IX92_27800	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
IX92_27800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IX92_27815	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_27825	COG2274	protein secretion by the type I secretion system
IX92_27845	COG0583	DNA-binding transcription factor activity
IX92_27880	COG1280	lysine exporter protein (LysE YggA)
IX92_27885	COG1917	Cupin 2, conserved barrel domain protein
IX92_27885	COG2207	Transcriptional regulator
IX92_27905	COG0625	glutathione transferase activity
IX92_27910	COG0583	DNA-binding transcription factor activity
IX92_27935	COG1917	Cupin 2, conserved barrel domain protein
IX92_27935	COG2207	Transcriptional regulator
IX92_27945	COG4608	Belongs to the ABC transporter superfamily
IX92_27950	COG0444	Belongs to the ABC transporter superfamily
IX92_27955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IX92_27975	COG1609	Transcriptional regulator
IX92_27985	COG4580	involved in the transport of maltose and maltodextrins
IX92_28035	COG2267	carboxylic ester hydrolase activity
IX92_28070	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IX92_28085	COG3706	GGDEF domain
IX92_28085	COG0745	RESPONSE REGULATOR receiver
IX92_28120	COG2003	Belongs to the UPF0758 family
IX92_28225	COG0305	Participates in initiation and elongation during chromosome replication
IX92_28230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IX92_28315	COG2026	Addiction module toxin, RelE StbE family
IX92_28340	COG1609	Transcriptional regulator
IX92_28350	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IX92_28360	COG1280	lysine exporter protein (LysE YggA)
IX92_28470	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IX92_28470	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IX92_28480	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IX92_28500	COG1181	Belongs to the D-alanine--D-alanine ligase family
IX92_28505	COG4191	Histidine kinase
IX92_28570	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family