locus-tag	class	description
B6A42_00015	COG3220	belongs to the UPF0276 family
B6A42_00035	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B6A42_00040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B6A42_00075	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B6A42_00090	COG0477	Major facilitator Superfamily
B6A42_00105	COG0745	RESPONSE REGULATOR receiver
B6A42_00120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B6A42_00130	COG0747	negative chemotaxis
B6A42_00175	COG1309	transcriptional regulator
B6A42_00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6A42_00185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B6A42_00190	COG2960	long-chain fatty acid transporting porin activity
B6A42_00200	COG0583	DNA-binding transcription factor activity
B6A42_00205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B6A42_00230	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B6A42_00250	COG0084	hydrolase, TatD family'
B6A42_00255	COG0805	protein transport
B6A42_00285	COG1322	Protein conserved in bacteria
B6A42_00295	COG1639	'signal transduction protein
B6A42_00325	COG2081	HI0933 family
B6A42_00335	COG1528	Iron-storage protein
B6A42_00340	COG0589	response to stress
B6A42_00345	COG0697	spore germination
B6A42_00365	COG1522	sequence-specific DNA binding
B6A42_00385	COG0006	proline dipeptidase activity
B6A42_00385	COG0006	proline dipeptidase activity
B6A42_00395	COG2022	thiamine diphosphate biosynthetic process
B6A42_00410	COG0352	thiamine-phosphate diphosphorylase activity
B6A42_00495	COG0183	Belongs to the thiolase family
B6A42_00505	COG0583	DNA-binding transcription factor activity
B6A42_00510	COG2814	Major facilitator Superfamily
B6A42_00520	COG0765	amino acid transport
B6A42_00530	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B6A42_00535	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B6A42_00540	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B6A42_00545	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B6A42_00570	COG3312	ion transport
B6A42_00575	COG1475	DNA binding
B6A42_00580	COG1192	Involved in chromosome partitioning
B6A42_00590	COG0445	tRNA wobble uridine modification
B6A42_00595	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B6A42_00600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B6A42_00605	COG0706	membrane insertase activity
B6A42_00610	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B6A42_00625	COG1126	abc transporter atp-binding protein
B6A42_00645	COG0592	DNA-directed DNA polymerase activity
B6A42_00660	COG0071	Belongs to the small heat shock protein (HSP20) family
B6A42_00665	COG3977	Valine--pyruvate aminotransferase
B6A42_00670	COG0751	glycine-tRNA ligase activity
B6A42_00680	COG2119	membrane
B6A42_00690	COG0425	Belongs to the sulfur carrier protein TusA family
B6A42_00705	COG0604	alcohol dehydrogenase
B6A42_00720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B6A42_00725	COG3978	acetolactate synthase activity
B6A42_00735	COG0606	chelatase, subunit chli
B6A42_00750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B6A42_00755	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B6A42_00765	COG2932	Transcriptional regulator
B6A42_00880	COG3084	Protein conserved in bacteria
B6A42_00885	COG4326	sporulation control protein
B6A42_00890	COG1272	protein, Hemolysin III
B6A42_00900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B6A42_00905	COG0569	domain protein
B6A42_00910	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B6A42_00910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B6A42_00920	COG0242	peptide deformylase activity
B6A42_00925	COG0758	DNA mediated transformation
B6A42_00930	COG2922	Belongs to the Smg family
B6A42_00935	COG0551	DNA topoisomerase type I activity
B6A42_00940	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B6A42_00945	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B6A42_00955	COG0408	coproporphyrinogen oxidase activity
B6A42_00970	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B6A42_01010	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B6A42_01020	COG2204	response regulator
B6A42_01025	COG3852	Histidine kinase
B6A42_01030	COG0174	glutamine synthetase
B6A42_01050	COG1490	D-aminoacyl-tRNA deacylase activity
B6A42_01065	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
B6A42_01075	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B6A42_01080	COG3031	protein transport across the cell outer membrane
B6A42_01090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B6A42_01100	COG2165	general secretion pathway protein
B6A42_01110	COG2165	general secretion pathway protein
B6A42_01115	COG4795	General secretion pathway protein
B6A42_01120	COG3156	type II secretion system protein K
B6A42_01125	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
B6A42_01130	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
B6A42_01145	COG0745	RESPONSE REGULATOR receiver
B6A42_01150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B6A42_01170	COG0596	Alpha beta hydrolase
B6A42_01180	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B6A42_01180	COG0316	Belongs to the HesB IscA family
B6A42_01185	COG0494	nUDIX hydrolase
B6A42_01190	COG1218	3'(2'),5'-bisphosphate nucleotidase
B6A42_01195	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B6A42_01200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B6A42_01205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B6A42_01220	COG1595	DNA-templated transcription, initiation
B6A42_01250	COG0848	biopolymer transport protein
B6A42_01260	COG2252	PERMEase
B6A42_01265	COG1561	YicC-like family, N-terminal region
B6A42_01275	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B6A42_01285	COG1560	Kdo2-lipid A biosynthetic process
B6A42_01290	COG1309	transcriptional regulator
B6A42_01295	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B6A42_01300	COG2003	Belongs to the UPF0758 family
B6A42_01330	COG0859	PFAM glycosyl transferase family 9
B6A42_01335	COG0463	Glycosyl transferase, family 2
B6A42_01340	COG0859	PFAM glycosyl transferase family 9
B6A42_01345	COG3642	lipopolysaccharide core region biosynthetic process
B6A42_01375	COG1519	Transferase
B6A42_01440	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B6A42_01460	COG1216	Glycosyl transferase, family 2
B6A42_01490	COG0438	transferase activity, transferring glycosyl groups
B6A42_01495	COG0438	transferase activity, transferring glycosyl groups
B6A42_01505	COG0438	transferase activity, transferring glycosyl groups
B6A42_01515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B6A42_01525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B6A42_01530	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
B6A42_01530	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
B6A42_01550	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
B6A42_01555	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B6A42_01565	COG1494	fructose-1,6-bisphosphatase
B6A42_01575	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B6A42_01580	COG0460	homoserine dehydrogenase
B6A42_01580	COG0527	aspartate kinase activity
B6A42_01585	COG0626	cystathionine gamma-synthase activity
B6A42_01595	COG0281	malic enzyme
B6A42_01610	COG1609	Transcriptional regulator
B6A42_01615	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B6A42_01645	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B6A42_01650	COG1053	succinate dehydrogenase
B6A42_01655	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
B6A42_01695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B6A42_01710	COG1045	serine acetyltransferase
B6A42_01715	COG1695	Transcriptional regulator
B6A42_01725	COG1573	uracil-dna glycosylase
B6A42_01730	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B6A42_01735	COG3068	Protein conserved in bacteria
B6A42_01740	COG1253	flavin adenine dinucleotide binding
B6A42_01755	COG0151	Belongs to the GarS family
B6A42_01770	COG0789	Transcriptional regulator
B6A42_01775	COG3706	GGDEF domain
B6A42_01780	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
B6A42_01790	COG2264	protein methyltransferase activity
B6A42_01795	COG0439	Biotin carboxylase
B6A42_01800	COG0511	ligase activity, forming carbon-carbon bonds
B6A42_01805	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B6A42_01810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B6A42_01825	COG2814	Major facilitator Superfamily
B6A42_01840	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B6A42_01850	COG2095	MarC family integral membrane protein
B6A42_01860	COG4232	protein-disulfide reductase activity
B6A42_01865	COG1438	arginine binding
B6A42_01870	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
B6A42_01875	COG0540	Belongs to the ATCase OTCase family
B6A42_01880	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B6A42_01895	COG1288	antiporter activity
B6A42_01900	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B6A42_01905	COG1027	Aspartate ammonia-lyase
B6A42_01925	COG3210	domain, Protein
B6A42_01930	COG3210	domain, Protein
B6A42_01965	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B6A42_01985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B6A42_01990	COG3954	Phosphoribulokinase
B6A42_02000	COG0429	hydrolase of the alpha beta-hydrolase fold
B6A42_02010	COG0488	(ABC) transporter
B6A42_02015	COG2249	NAD(P)H dehydrogenase (quinone) activity
B6A42_02030	COG1047	Peptidyl-prolyl cis-trans
B6A42_02040	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B6A42_02055	COG0402	S-adenosylhomocysteine deaminase activity
B6A42_02060	COG0557	exoribonuclease II activity
B6A42_02065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B6A42_02070	COG0051	transcription antitermination factor activity, RNA binding
B6A42_02080	COG0088	Forms part of the polypeptide exit tunnel
B6A42_02100	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B6A42_02105	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B6A42_02135	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B6A42_02150	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B6A42_02165	COG1841	ribosomal large subunit assembly
B6A42_02175	COG0201	protein transport
B6A42_02185	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B6A42_02190	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B6A42_02205	COG0203	ribosomal protein L17
B6A42_02215	COG0545	Peptidyl-prolyl cis-trans isomerase
B6A42_02230	COG2153	protein acetylation
B6A42_02240	COG0737	Belongs to the 5'-nucleotidase family
B6A42_02245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B6A42_02245	COG1648	precorrin-2 dehydrogenase activity
B6A42_02265	COG0529	Catalyzes the synthesis of activated sulfate
B6A42_02275	COG0735	belongs to the Fur family
B6A42_02280	COG0784	Response regulator, receiver
B6A42_02280	COG5002	protein histidine kinase activity
B6A42_02280	COG2205	protein histidine kinase activity
B6A42_02285	COG3437	response regulator, receiver
B6A42_02420	COG3157	Type VI secretion system effector, Hcp
B6A42_02530	COG3692	DNA binding
B6A42_02535	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B6A42_02560	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B6A42_02645	COG2239	Acts as a magnesium transporter
B6A42_02650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B6A42_02660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B6A42_02665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B6A42_02680	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
B6A42_02690	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B6A42_02695	COG0517	IMP dehydrogenase activity
B6A42_02695	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B6A42_02710	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B6A42_02730	COG5007	Belongs to the BolA IbaG family
B6A42_02765	COG0589	response to stress
B6A42_02790	COG0039	L-malate dehydrogenase activity
B6A42_02800	COG0251	oxidation-reduction process
B6A42_02805	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
B6A42_02820	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B6A42_02850	COG4269	membrane
B6A42_02860	COG0525	valine-tRNA ligase activity
B6A42_02865	COG2927	DNA polymerase III (CHI subunit)
B6A42_02885	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B6A42_02890	COG1546	Belongs to the CinA family
B6A42_02895	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B6A42_02900	COG2137	regulation of response to DNA damage stimulus
B6A42_02910	COG0527	aspartate kinase activity
B6A42_02965	COG0511	ligase activity, forming carbon-carbon bonds
B6A42_02965	COG5016	pyruvate
B6A42_02970	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
B6A42_02975	COG2130	NADP-dependent
B6A42_02980	COG1238	metal cluster binding
B6A42_02985	COG0612	Peptidase, M16
B6A42_03000	COG1854	S-ribosylhomocysteine lyase activity
B6A42_03025	COG3437	response regulator, receiver
B6A42_03085	COG0473	3-isopropylmalate dehydrogenase activity
B6A42_03090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B6A42_03110	COG0583	DNA-binding transcription factor activity
B6A42_03115	COG1022	Amp-dependent synthetase and ligase
B6A42_03120	COG0028	Belongs to the TPP enzyme family
B6A42_03125	COG0440	acetolactate synthase activity
B6A42_03130	COG0584	glycerophosphoryl diester phosphodiesterase
B6A42_03135	COG2271	Major facilitator Superfamily
B6A42_03140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B6A42_03160	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
B6A42_03170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B6A42_03175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B6A42_03205	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B6A42_03210	COG1595	DNA-templated transcription, initiation
B6A42_03220	COG3026	antisigma factor binding
B6A42_03225	COG3086	response to oxidative stress
B6A42_03230	COG0481	GTPase activity
B6A42_03235	COG0681	Belongs to the peptidase S26 family
B6A42_03245	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B6A42_03250	COG1381	Involved in DNA repair and RecF pathway recombination
B6A42_03260	COG0736	holo-[acyl-carrier-protein] synthase activity
B6A42_03270	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B6A42_03275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B6A42_03290	COG0148	phosphopyruvate hydratase activity
B6A42_03295	COG0617	tRNA 3'-terminal CCA addition
B6A42_03310	COG4991	sh3 domain protein
B6A42_03315	COG0306	phosphate transporter
B6A42_03320	COG1392	Phosphate transport regulator
B6A42_03325	COG3025	triphosphatase activity
B6A42_03330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B6A42_03340	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B6A42_03350	COG0745	RESPONSE REGULATOR receiver
B6A42_03385	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B6A42_03400	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
B6A42_03425	COG1846	Transcriptional regulator
B6A42_03430	COG0534	Mate efflux family protein
B6A42_03455	COG3066	DNA modification
B6A42_03470	COG0730	response to heat
B6A42_03480	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B6A42_03485	COG1283	sodium-dependent phosphate transmembrane transporter activity
B6A42_03490	COG0583	DNA-binding transcription factor activity
B6A42_03495	COG0640	Transcriptional regulator
B6A42_03500	COG0268	Binds directly to 16S ribosomal RNA
B6A42_03505	COG0728	peptidoglycan biosynthetic process
B6A42_03510	COG0196	riboflavin kinase activity
B6A42_03525	COG1047	Peptidyl-prolyl cis-trans
B6A42_03530	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B6A42_03535	COG1966	Carbon starvation protein
B6A42_03545	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B6A42_03550	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B6A42_03555	COG2971	BadF BadG BcrA BcrD
B6A42_03565	COG1737	Transcriptional regulator
B6A42_03570	COG1472	Belongs to the glycosyl hydrolase 3 family
B6A42_03575	COG3279	Response regulator of the LytR AlgR family
B6A42_03580	COG3275	phosphorelay sensor kinase activity
B6A42_03585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B6A42_03590	COG1605	Chorismate mutase
B6A42_03590	COG0287	Prephenate dehydrogenase
B6A42_03595	COG0739	heme binding
B6A42_03605	COG0488	(ABC) transporter
B6A42_03615	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
B6A42_03625	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
B6A42_03635	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B6A42_03640	COG1605	Chorismate mutase
B6A42_03640	COG0077	Prephenate dehydratase
B6A42_03645	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B6A42_03650	COG0741	lytic transglycosylase activity
B6A42_03655	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B6A42_03660	COG0564	pseudouridine synthase activity
B6A42_03670	COG0542	response to heat
B6A42_03715	COG0483	inositol monophosphate 1-phosphatase activity
B6A42_03725	COG1959	2 iron, 2 sulfur cluster binding
B6A42_03730	COG1104	cysteine desulfurase activity
B6A42_03735	COG0822	iron-sulfur transferase activity
B6A42_03755	COG0633	Ferredoxin
B6A42_03760	COG2975	iron-sulfur cluster assembly
B6A42_03765	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B6A42_03775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B6A42_03790	COG0583	DNA-binding transcription factor activity
B6A42_03800	COG2169	Transcriptional regulator
B6A42_03825	COG4964	Belongs to the GSP D family
B6A42_03890	COG2169	Transcriptional regulator
B6A42_03895	COG1486	melibiose metabolic process
B6A42_03910	COG3408	Glycogen debranching enzyme
B6A42_03910	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
B6A42_03925	COG1309	transcriptional regulator
B6A42_03935	COG2731	YhcH YjgK YiaL family protein
B6A42_03945	COG1609	Transcriptional regulator
B6A42_03950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B6A42_03955	COG1085	galactose-1-phosphate uridylyltransferase
B6A42_03965	COG2017	converts alpha-aldose to the beta-anomer
B6A42_03985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B6A42_03985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B6A42_03985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B6A42_04000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B6A42_04010	COG2171	N-acyltransferase activity
B6A42_04015	COG0450	alkyl hydroperoxide reductase
B6A42_04020	COG0583	DNA-binding transcription factor activity
B6A42_04035	COG0517	IMP dehydrogenase activity
B6A42_04040	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B6A42_04050	COG1862	Preprotein translocase
B6A42_04055	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B6A42_04060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B6A42_04080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B6A42_04100	COG0745	RESPONSE REGULATOR receiver
B6A42_04105	COG5002	protein histidine kinase activity
B6A42_04125	COG0573	inorganic phosphate transmembrane transporter activity
B6A42_04135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B6A42_04155	COG3141	response to X-ray
B6A42_04160	COG1309	transcriptional regulator
B6A42_04165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6A42_04215	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
B6A42_04220	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B6A42_04225	COG2166	iron-sulfur cluster assembly
B6A42_04235	COG1426	Protein conserved in bacteria
B6A42_04245	COG0124	histidyl-tRNA synthetase
B6A42_04250	COG2976	Protein conserved in bacteria
B6A42_04260	COG1160	GTP binding
B6A42_04270	COG2199	diguanylate cyclase activity
B6A42_04270	COG2203	Gaf domain
B6A42_04285	COG0516	GMP reductase activity
B6A42_04285	COG0517	IMP dehydrogenase activity
B6A42_04300	COG1584	GPR1 FUN34 yaaH family protein
B6A42_04310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B6A42_04335	COG0784	Response regulator, receiver
B6A42_04335	COG0835	chemotaxis
B6A42_04400	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B6A42_04415	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B6A42_04420	COG1301	dicarboxylic acid transport
B6A42_04425	COG0443	Heat shock 70 kDa protein
B6A42_04440	COG4970	Tfp pilus assembly protein FimT
B6A42_04460	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
B6A42_04465	COG0590	tRNA wobble adenosine to inosine editing
B6A42_04470	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
B6A42_04475	COG0047	phosphoribosylformylglycinamidine synthase activity
B6A42_04475	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B6A42_04500	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B6A42_04505	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B6A42_04510	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B6A42_04515	COG1187	pseudouridine synthase activity
B6A42_04520	COG2840	Smr protein MutS2
B6A42_04545	COG3104	oligopeptide transport
B6A42_04550	COG0367	asparagine synthase
B6A42_04555	COG4651	solute:proton antiporter activity
B6A42_04555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B6A42_04560	COG1940	carbohydrate kinase activity
B6A42_04560	COG1846	Transcriptional regulator
B6A42_04565	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B6A42_04570	COG1263	PTS System
B6A42_04570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B6A42_04570	COG2190	(PTS) system
B6A42_04590	COG0716	FMN binding
B6A42_04600	COG0596	Alpha beta hydrolase
B6A42_04605	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
B6A42_04610	COG0033	Phosphoglucomutase
B6A42_04630	COG2009	succinate dehydrogenase
B6A42_04635	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B6A42_04640	COG1053	succinate dehydrogenase
B6A42_04645	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B6A42_04650	COG0567	Dehydrogenase, E1 component
B6A42_04655	COG0508	dehydrogenase complex catalyzes the overall conversion of
B6A42_04690	COG3098	single-species biofilm formation
B6A42_04695	COG0564	pseudouridine synthase activity
B6A42_04705	COG0142	geranyltranstransferase activity
B6A42_04730	COG0301	tRNA thio-modification
B6A42_04730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B6A42_04735	COG0583	DNA-binding transcription factor activity
B6A42_04770	COG3706	GGDEF domain
B6A42_04770	COG0745	RESPONSE REGULATOR receiver
B6A42_04790	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
B6A42_04805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B6A42_04810	COG1393	Belongs to the ArsC family
B6A42_04840	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
B6A42_04845	COG0437	4 iron, 4 sulfur cluster binding
B6A42_04850	COG3301	Polysulphide reductase, NrfD
B6A42_04855	COG1138	Cytochrome C-type biogenesis protein
B6A42_04865	COG3088	subunit of a heme lyase
B6A42_04865	COG4235	cytochrome complex assembly
B6A42_04875	COG2837	iron assimilation
B6A42_04890	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B6A42_04910	COG1516	flagellar protein fliS
B6A42_04915	COG2204	response regulator
B6A42_04920	COG4191	Histidine kinase
B6A42_04925	COG2204	response regulator
B6A42_04930	COG1677	Flagellar hook-basal body complex protein FliE
B6A42_04940	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B6A42_04990	COG1987	bacterial-type flagellum assembly
B6A42_04995	COG1684	flagellar biosynthetic protein fliR
B6A42_05015	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B6A42_05025	COG2860	membrane
B6A42_05030	COG3101	peptidyl-lysine hydroxylation
B6A42_05060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B6A42_05070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B6A42_05085	COG0101	tRNA pseudouridine synthase activity
B6A42_05100	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
B6A42_05105	COG1286	toxin biosynthetic process
B6A42_05110	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B6A42_05115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B6A42_05120	COG1121	(ABC) transporter
B6A42_05125	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
B6A42_05130	COG4977	sequence-specific DNA binding
B6A42_05135	COG1918	ferrous iron import across plasma membrane
B6A42_05155	COG0018	arginyl-trna synthetase
B6A42_05160	COG3102	Protein conserved in bacteria
B6A42_05170	COG2062	phosphohistidine phosphatase, SixA
B6A42_05185	COG0455	bacterial-type flagellum organization
B6A42_05200	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
B6A42_05210	COG2201	protein-glutamate methylesterase activity
B6A42_05215	COG1192	Involved in chromosome partitioning
B6A42_05225	COG0835	chemotaxis
B6A42_05235	COG4133	protoheme IX ABC transporter activity
B6A42_05250	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B6A42_05260	COG1138	Cytochrome C-type biogenesis protein
B6A42_05265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B6A42_05270	COG3088	subunit of a heme lyase
B6A42_05270	COG4235	cytochrome complex assembly
B6A42_05280	COG2853	Lipoprotein
B6A42_05285	COG2067	long-chain fatty acid transport protein
B6A42_05290	COG2067	long-chain fatty acid transport protein
B6A42_05305	COG0183	Belongs to the thiolase family
B6A42_05315	COG0778	Nitroreductase
B6A42_05320	COG0583	DNA-binding transcription factor activity
B6A42_05330	COG2832	Protein of unknown function (DUF454)
B6A42_05335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B6A42_05345	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B6A42_05350	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B6A42_05375	COG0745	RESPONSE REGULATOR receiver
B6A42_05380	COG2205	protein histidine kinase activity
B6A42_05385	COG1653	transport
B6A42_05400	COG3842	ATPase activity
B6A42_05405	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B6A42_05410	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B6A42_05415	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B6A42_05425	COG2204	response regulator
B6A42_05455	COG0776	regulation of translation
B6A42_05460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B6A42_05465	COG1555	photosystem II stabilization
B6A42_05475	COG0539	negative regulation of cytoplasmic translation
B6A42_05485	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
B6A42_05490	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
B6A42_05495	COG0284	orotidine-5'-phosphate decarboxylase activity
B6A42_05585	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B6A42_05595	COG0252	asparaginase activity
B6A42_05600	COG0616	signal peptide processing
B6A42_05610	COG0788	formyltetrahydrofolate deformylase activity
B6A42_05640	COG2267	carboxylic ester hydrolase activity
B6A42_05645	COG0318	PFAM AMP-dependent synthetase and ligase
B6A42_05650	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
B6A42_05655	COG0659	secondary active sulfate transmembrane transporter activity
B6A42_05660	COG1530	ribonuclease E activity
B6A42_05665	COG0564	pseudouridine synthase activity
B6A42_05670	COG0424	maF-like protein
B6A42_05675	COG1399	metal-binding, possibly nucleic acid-binding protein
B6A42_05690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B6A42_05720	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B6A42_05730	COG0470	DNA polymerase III
B6A42_05735	COG0084	hydrolase, TatD family'
B6A42_05740	COG1263	PTS System
B6A42_05740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B6A42_05760	COG4667	esterase of the alpha-beta hydrolase superfamily
B6A42_05770	COG1940	carbohydrate kinase activity
B6A42_05775	COG0835	chemotaxis
B6A42_05775	COG0784	Response regulator, receiver
B6A42_05795	COG1028	Short-chain dehydrogenase reductase Sdr
B6A42_05800	COG0616	signal peptide processing
B6A42_05805	COG0513	Belongs to the DEAD box helicase family
B6A42_05820	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B6A42_05840	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
B6A42_05850	COG1169	isochorismate synthase
B6A42_05855	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
B6A42_05860	COG0596	Alpha beta hydrolase
B6A42_05870	COG1441	menaquinone biosynthetic process
B6A42_05885	COG2814	Major facilitator Superfamily
B6A42_05910	COG1522	sequence-specific DNA binding
B6A42_05930	COG3126	Type III secretion system lipoprotein chaperone (YscW)
B6A42_05975	COG1414	Transcriptional regulator
B6A42_05980	COG0280	phosphate acetyltransferase
B6A42_06005	COG2855	membrane
B6A42_06020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B6A42_06025	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B6A42_06030	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B6A42_06055	COG3876	Protein conserved in bacteria
B6A42_06080	COG1770	oligopeptidase
B6A42_06100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6A42_06140	COG0330	HflC and HflK could
B6A42_06155	COG3710	Transcriptional regulator
B6A42_06170	COG0840	transmembrane signaling receptor activity
B6A42_06175	COG1404	Belongs to the peptidase S8 family
B6A42_06205	COG2067	long-chain fatty acid transport protein
B6A42_06220	COG0601	transmembrane transport
B6A42_06225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B6A42_06230	COG0444	Belongs to the ABC transporter superfamily
B6A42_06240	COG0435	Glutathione S-transferase
B6A42_06245	COG3706	GGDEF domain
B6A42_06250	COG0857	belongs to the CobB CobQ family
B6A42_06250	COG0280	phosphate acetyltransferase
B6A42_06260	COG3092	negative regulation of chromosome organization
B6A42_06265	COG0686	Belongs to the AlaDH PNT family
B6A42_06275	COG1674	ftsk spoiiie
B6A42_06295	COG2186	Transcriptional regulator
B6A42_06310	COG0537	adenosine 5'-monophosphoramidase activity
B6A42_06340	COG1252	NADH dehydrogenase
B6A42_06370	COG4591	ABC-type transport system involved in lipoprotein release permease component
B6A42_06395	COG1132	(ABC) transporter
B6A42_06420	COG2718	Belongs to the UPF0229 family
B6A42_06425	COG2766	serine protein kinase
B6A42_06445	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B6A42_06460	COG1882	Formate acetyltransferase
B6A42_06480	COG4215	(ABC) transporter
B6A42_06495	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B6A42_06525	COG1737	Transcriptional regulator
B6A42_06550	COG3070	regulator of competence-specific genes
B6A42_06585	COG1032	radical SAM domain protein
B6A42_06610	COG0583	DNA-binding transcription factor activity
B6A42_06615	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B6A42_06620	COG1764	response to oxidative stress
B6A42_06625	COG1846	Transcriptional regulator
B6A42_06635	COG0583	DNA-binding transcription factor activity
B6A42_06645	COG0673	inositol 2-dehydrogenase activity
B6A42_06650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B6A42_06670	COG0840	transmembrane signaling receptor activity
B6A42_06675	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B6A42_06740	COG1858	cytochrome C peroxidase
B6A42_06755	COG0443	Heat shock 70 kDa protein
B6A42_06820	COG1301	dicarboxylic acid transport
B6A42_06825	COG0159	tryptophan synthase activity
B6A42_06830	COG0133	tryptophan synthase activity
B6A42_06835	COG0135	phosphoribosylanthranilate isomerase activity
B6A42_06835	COG0134	indole-3-glycerol-phosphate synthase activity
B6A42_06840	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B6A42_06850	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B6A42_06860	COG0613	PHP domain protein
B6A42_06880	COG1187	pseudouridine synthase activity
B6A42_06885	COG0384	phenazine biosynthesis protein PhzF
B6A42_06895	COG2814	Major facilitator Superfamily
B6A42_06910	COG0492	ferredoxin-NADP+ reductase activity
B6A42_06940	COG0612	Peptidase, M16
B6A42_06950	COG2949	membrane
B6A42_06960	COG0281	malic enzyme
B6A42_06980	COG1448	Aminotransferase
B6A42_06985	COG2770	Histidine kinase
B6A42_06985	COG3437	response regulator, receiver
B6A42_06995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B6A42_07005	COG0017	Asparaginyl-tRNA synthetase
B6A42_07010	COG0840	transmembrane signaling receptor activity
B6A42_07020	COG0814	amino acid
B6A42_07030	COG1760	l-serine dehydratase
B6A42_07035	COG0814	amino acid
B6A42_07040	COG0494	nUDIX hydrolase
B6A42_07080	COG3283	Transcriptional regulator of aromatic amino acids metabolism
B6A42_07085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B6A42_07105	COG3706	GGDEF domain
B6A42_07110	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B6A42_07135	COG2989	Protein conserved in bacteria
B6A42_07140	COG3108	Peptidase M15
B6A42_07145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B6A42_07160	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B6A42_07195	COG4667	esterase of the alpha-beta hydrolase superfamily
B6A42_07200	COG0783	Belongs to the Dps family
B6A42_07210	COG0531	amino acid
B6A42_07215	COG2962	Rard protein
B6A42_07340	COG0653	protein targeting
B6A42_07380	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B6A42_07425	COG2026	Addiction module toxin, RelE StbE family
B6A42_07440	COG1683	Conserved Protein
B6A42_07470	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B6A42_07470	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B6A42_07520	COG0456	acetyltransferase
B6A42_07540	COG0730	response to heat
B6A42_07550	COG1028	Short-chain dehydrogenase reductase Sdr
B6A42_07560	COG2824	Alkylphosphonate utilization operon protein PhnA
B6A42_07575	COG0456	acetyltransferase
B6A42_07600	COG3040	lipid binding
B6A42_07615	COG3122	Protein conserved in bacteria
B6A42_07670	COG0454	-acetyltransferase
B6A42_07675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B6A42_07700	COG0456	acetyltransferase
B6A42_07715	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B6A42_07720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B6A42_07740	COG2195	Cleaves the N-terminal amino acid of tripeptides
B6A42_07760	COG0625	glutathione transferase activity
B6A42_07775	COG2885	chlorophyll binding
B6A42_07805	COG2986	histidine ammonia-lyase
B6A42_07815	COG0010	Belongs to the arginase family
B6A42_07820	COG1228	amidohydrolase
B6A42_07830	COG4326	sporulation control protein
B6A42_07870	COG1346	cytolysis
B6A42_07880	COG2925	Exonuclease
B6A42_07930	COG0702	epimerase
B6A42_07935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B6A42_07945	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
B6A42_07955	COG0406	alpha-ribazole phosphatase activity
B6A42_07970	COG4139	cobalamin transport
B6A42_07990	COG5002	protein histidine kinase activity
B6A42_07990	COG5001	Diguanylate cyclase
B6A42_07990	COG3447	MASE1 domain protein
B6A42_08000	COG2814	Major facilitator Superfamily
B6A42_08010	COG1119	ATPase activity
B6A42_08020	COG0784	Response regulator, receiver
B6A42_08020	COG5002	protein histidine kinase activity
B6A42_08030	COG1451	nucleotide metabolic process
B6A42_08045	COG3063	Type IV pilus biogenesis stability protein PilW
B6A42_08070	COG2203	Gaf domain
B6A42_08070	COG3706	GGDEF domain
B6A42_08070	COG4251	negative regulation of phosphorylation
B6A42_08070	COG5001	Diguanylate cyclase
B6A42_08085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6A42_08110	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B6A42_08115	COG0515	serine threonine protein kinase
B6A42_08215	COG3501	Rhs element vgr protein
B6A42_08230	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B6A42_08235	COG0372	Belongs to the citrate synthase family
B6A42_08270	COG0602	queuosine metabolic process
B6A42_08310	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B6A42_08315	COG0840	transmembrane signaling receptor activity
B6A42_08320	COG1254	Belongs to the acylphosphatase family
B6A42_08325	COG2920	part of a sulfur-relay system
B6A42_08330	COG0670	Belongs to the BI1 family
B6A42_08335	COG1126	abc transporter atp-binding protein
B6A42_08340	COG0765	amino acid transport
B6A42_08350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B6A42_08360	COG1666	GTP binding
B6A42_08365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B6A42_08395	COG3008	intermembrane lipid transfer
B6A42_08400	COG2995	paraquat-inducible protein a
B6A42_08405	COG1132	(ABC) transporter
B6A42_08410	COG1956	GAF domain-containing protein
B6A42_08415	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
B6A42_08430	COG0308	aminopeptidase N
B6A42_08445	COG0167	dihydroorotate dehydrogenase activity
B6A42_08455	COG0116	Belongs to the methyltransferase superfamily
B6A42_08455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B6A42_08465	COG0488	(ABC) transporter
B6A42_08480	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B6A42_08485	COG1067	ATP-dependent peptidase activity
B6A42_08540	COG0789	Transcriptional regulator
B6A42_09030	COG3424	synthase
B6A42_09045	COG1942	4-Oxalocrotonate Tautomerase
B6A42_09070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B6A42_09190	COG3278	Belongs to the heme-copper respiratory oxidase family
B6A42_09205	COG2010	Cytochrome c
B6A42_09215	COG2217	Heavy metal translocating P-type atpase
B6A42_09230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B6A42_09235	COG0589	response to stress
B6A42_09265	COG1176	ABC-type spermidine putrescine transport system, permease component I
B6A42_09270	COG1177	transmembrane transport
B6A42_09275	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B6A42_09280	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B6A42_09290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B6A42_09295	COG0004	ammonium transporteR
B6A42_09310	COG0437	4 iron, 4 sulfur cluster binding
B6A42_09315	COG0243	molybdopterin cofactor binding
B6A42_09315	COG3383	formate dehydrogenase (NAD+) activity
B6A42_09345	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B6A42_09355	COG3038	cytochrome b561
B6A42_09430	COG3710	Transcriptional regulator
B6A42_09450	COG1028	Short-chain dehydrogenase reductase Sdr
B6A42_09465	COG0488	(ABC) transporter
B6A42_09475	COG1595	DNA-templated transcription, initiation
B6A42_09490	COG3852	Histidine kinase
B6A42_09505	COG4662	Binding-protein-dependent transport system inner membrane component
B6A42_09510	COG3842	ATPase activity
B6A42_09515	COG0746	molybdenum cofactor guanylyltransferase activity
B6A42_09535	COG1940	carbohydrate kinase activity
B6A42_09550	COG0840	transmembrane signaling receptor activity
B6A42_09555	COG0791	NLP P60 protein
B6A42_09575	COG0307	riboflavin synthase, alpha
B6A42_09625	COG2204	response regulator
B6A42_09635	COG0438	transferase activity, transferring glycosyl groups
B6A42_09680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B6A42_09735	COG4615	Cyclic peptide transporter
B6A42_09745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B6A42_09750	COG1120	ATPase activity
B6A42_09755	COG2977	Belongs to the P-Pant transferase superfamily
B6A42_09765	COG3835	regulator
B6A42_09780	COG0583	DNA-binding transcription factor activity
B6A42_09785	COG2814	Major facilitator Superfamily
B6A42_09800	COG3713	MltA-interacting MipA family protein
B6A42_09810	COG0745	RESPONSE REGULATOR receiver
B6A42_09815	COG0814	amino acid
B6A42_09825	COG1475	DNA binding
B6A42_09830	COG3969	phosphoadenosine phosphosulfate
B6A42_09845	COG0583	DNA-binding transcription factor activity
B6A42_09885	COG2116	formate transmembrane transporter activity
B6A42_09890	COG2146	nitrite reductase [NAD(P)H] activity
B6A42_09925	COG4565	transcriptional regulatory protein
B6A42_09930	COG3290	protein histidine kinase activity
B6A42_09950	COG0848	biopolymer transport protein
B6A42_09955	COG0811	peptide transport
B6A42_09960	COG0811	peptide transport
B6A42_09975	COG3710	Transcriptional regulator
B6A42_09985	COG0745	RESPONSE REGULATOR receiver
B6A42_09990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B6A42_10065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B6A42_10070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B6A42_10075	COG0633	Ferredoxin
B6A42_10100	COG0019	diaminopimelate decarboxylase activity
B6A42_10220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B6A42_10225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6A42_10245	COG0463	Glycosyl transferase, family 2
B6A42_10305	COG1279	arginine transmembrane transporter activity
B6A42_10310	COG0583	DNA-binding transcription factor activity
B6A42_10315	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B6A42_10340	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
B6A42_10375	COG0307	riboflavin synthase, alpha
B6A42_10430	COG0242	peptide deformylase activity
B6A42_10435	COG0519	Catalyzes the synthesis of GMP from XMP
B6A42_10450	COG4580	involved in the transport of maltose and maltodextrins
B6A42_10455	COG0778	Nitroreductase
B6A42_10535	COG1115	amino acid carrier protein
B6A42_10540	COG1280	lysine exporter protein (LysE YggA)
B6A42_10545	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
B6A42_10550	COG0352	thiamine-phosphate diphosphorylase activity
B6A42_10580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B6A42_10590	COG1012	belongs to the aldehyde dehydrogenase family
B6A42_10600	COG0583	DNA-binding transcription factor activity
B6A42_10625	COG2267	carboxylic ester hydrolase activity
B6A42_10650	COG1609	Transcriptional regulator
B6A42_10670	COG1609	Transcriptional regulator
B6A42_10685	COG0745	RESPONSE REGULATOR receiver
B6A42_10705	COG1858	cytochrome C peroxidase
B6A42_10710	COG0784	Response regulator, receiver
B6A42_10710	COG2205	protein histidine kinase activity
B6A42_10720	COG0488	(ABC) transporter
B6A42_10725	COG3437	response regulator, receiver
B6A42_10735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B6A42_10760	COG0673	inositol 2-dehydrogenase activity
B6A42_10765	COG3718	enzyme involved in inositol metabolism
B6A42_10790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B6A42_10895	COG4211	Belongs to the binding-protein-dependent transport system permease family
B6A42_10905	COG0277	FAD linked oxidase domain protein
B6A42_10915	COG0583	DNA-binding transcription factor activity
B6A42_10935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B6A42_10975	COG1263	PTS System
B6A42_10975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B6A42_10985	COG1335	isochorismatase
B6A42_10990	COG1741	Belongs to the pirin family
B6A42_11080	COG3706	GGDEF domain
B6A42_11105	COG2133	pyrroloquinoline quinone binding
B6A42_11115	COG1902	pentaerythritol trinitrate reductase activity
B6A42_11150	COG2197	response regulator
B6A42_11180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B6A42_11185	COG3099	Belongs to the UPF0263 family
B6A42_11220	COG1607	acyl-coa hydrolase
B6A42_11225	COG2350	Protein conserved in bacteria
B6A42_11240	COG3313	Fe-S protein
B6A42_11250	COG4134	Bacterial extracellular solute-binding protein
B6A42_11260	COG4136	ATPase activity
B6A42_11265	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B6A42_11270	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B6A42_11275	COG0564	pseudouridine synthase activity
B6A42_11290	COG0626	cystathionine gamma-synthase activity
B6A42_11295	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
B6A42_11300	COG5380	lipid catabolic process
B6A42_11305	COG2818	Glycosylase
B6A42_11325	COG1983	PspC domain protein
B6A42_11335	COG1842	Phage shock protein A
B6A42_11340	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B6A42_11350	COG4168	peptide transport system, permease
B6A42_11355	COG4171	peptide transport system, permease
B6A42_11365	COG4172	Belongs to the ABC transporter superfamily
B6A42_11380	COG1227	inorganic diphosphatase activity
B6A42_11390	COG0217	transcriptional regulatory protein
B6A42_11395	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B6A42_11395	COG0140	phosphoribosyl-ATP diphosphatase activity
B6A42_11400	COG0107	imidazoleglycerol-phosphate synthase activity
B6A42_11405	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B6A42_11410	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B6A42_11415	COG0131	Imidazoleglycerol-phosphate dehydratase
B6A42_11415	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B6A42_11425	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B6A42_11445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B6A42_11455	COG0482	sulfurtransferase activity
B6A42_11465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B6A42_11475	COG2268	Band 7 protein
B6A42_11525	COG0156	8-amino-7-oxononanoate synthase activity
B6A42_11535	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B6A42_11555	COG0730	response to heat
B6A42_11570	COG2850	peptidyl-arginine hydroxylation
B6A42_11575	COG0840	transmembrane signaling receptor activity
B6A42_11580	COG0708	Exodeoxyribonuclease III
B6A42_11585	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B6A42_11610	COG0463	Glycosyl transferase, family 2
B6A42_11615	COG0745	RESPONSE REGULATOR receiver
B6A42_11620	COG5002	protein histidine kinase activity
B6A42_11620	COG3850	Histidine kinase
B6A42_11635	COG1940	carbohydrate kinase activity
B6A42_11650	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B6A42_11655	COG1881	PFAM PEBP family protein
B6A42_11660	COG1902	pentaerythritol trinitrate reductase activity
B6A42_11680	COG0784	Response regulator, receiver
B6A42_11680	COG5002	protein histidine kinase activity
B6A42_11705	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
B6A42_11710	COG2885	chlorophyll binding
B6A42_11730	COG0811	peptide transport
B6A42_11735	COG0824	Thioesterase
B6A42_11745	COG4890	Cyd operon protein YbgT
B6A42_11750	COG1294	oxidase, subunit
B6A42_11755	COG1271	oxidase subunit
B6A42_11760	COG2255	four-way junction helicase activity
B6A42_11770	COG0840	transmembrane signaling receptor activity
B6A42_11775	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B6A42_11795	COG1028	Short-chain dehydrogenase reductase Sdr
B6A42_11805	COG0243	molybdopterin cofactor binding
B6A42_11810	COG3005	denitrification pathway
B6A42_11815	COG4459	periplasmic nitrate reductase
B6A42_11820	COG0390	transport system, permease component
B6A42_11855	COG0542	response to heat
B6A42_11860	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B6A42_11865	COG1278	Cold shock
B6A42_11875	COG1187	pseudouridine synthase activity
B6A42_11885	COG1801	Protein of unknown function DUF72
B6A42_11895	COG0500	methyltransferase
B6A42_11900	COG4067	protein conserved in archaea
B6A42_11900	COG0189	ligase activity
B6A42_11935	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
B6A42_11950	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B6A42_11955	COG0745	RESPONSE REGULATOR receiver
B6A42_11970	COG3070	regulator of competence-specific genes
B6A42_11995	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B6A42_12000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B6A42_12025	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
B6A42_12030	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B6A42_12035	COG1435	thymidine kinase activity
B6A42_12040	COG0215	cysteine-tRNA ligase activity
B6A42_12045	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B6A42_12055	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
B6A42_12060	COG3012	SEC-C Motif Domain Protein
B6A42_12065	COG3139	Protein of unknown function (DUF1315)
B6A42_12075	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B6A42_12095	COG2226	methyltransferase
B6A42_12135	COG2983	Belongs to the UPF0260 family
B6A42_12165	COG3100	YcgL domain-containing protein
B6A42_12175	COG2894	cell division
B6A42_12185	COG1012	belongs to the aldehyde dehydrogenase family
B6A42_12185	COG1454	alcohol dehydrogenase
B6A42_12190	COG2095	MarC family integral membrane protein
B6A42_12195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B6A42_12200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B6A42_12205	COG1757	Na H antiporter
B6A42_12230	COG3082	Protein of unknown function (DUF1414)
B6A42_12255	COG0840	transmembrane signaling receptor activity
B6A42_12300	COG0123	including yeast histone deacetylase and acetoin utilization protein
B6A42_12310	COG1881	PFAM PEBP family protein
B6A42_12320	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B6A42_12345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B6A42_12355	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B6A42_12360	COG0302	gtp cyclohydrolase
B6A42_12370	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
B6A42_12380	COG2982	Protein involved in outer membrane biogenesis
B6A42_12385	COG0572	uridine kinase
B6A42_12390	COG0489	protein tyrosine kinase activity
B6A42_12395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B6A42_12395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B6A42_12450	COG0517	IMP dehydrogenase activity
B6A42_12460	COG3706	GGDEF domain
B6A42_12465	COG0314	molybdopterin synthase activity
B6A42_12470	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
B6A42_12475	COG0315	cyclic pyranopterin monophosphate synthase activity
B6A42_12480	COG0521	Mo-molybdopterin cofactor biosynthetic process
B6A42_12485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B6A42_12490	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B6A42_12495	COG2198	Histidine kinase
B6A42_12525	COG0739	heme binding
B6A42_12550	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B6A42_12565	COG2204	response regulator
B6A42_12570	COG2885	chlorophyll binding
B6A42_12590	COG1987	bacterial-type flagellum assembly
B6A42_12600	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B6A42_12615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B6A42_12620	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
B6A42_12625	COG1516	flagellar protein fliS
B6A42_12640	COG1580	Controls the rotational direction of flagella during chemotaxis
B6A42_12645	COG1191	sigma factor activity
B6A42_12650	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B6A42_12655	COG1360	Flagellar Motor Protein
B6A42_12685	COG1706	bacterial-type flagellum-dependent cell motility
B6A42_12690	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
B6A42_12695	COG4786	Flagellar basal body rod
B6A42_12705	COG1749	Flagellar hook protein flgE
B6A42_12715	COG1558	bacterial-type flagellum-dependent cell motility
B6A42_12740	COG0741	lytic transglycosylase activity
B6A42_12740	COG1388	LysM domain
B6A42_12745	COG4657	Part of a membrane complex involved in electron transport
B6A42_12755	COG4656	Part of a membrane complex involved in electron transport
B6A42_12760	COG4658	electron transport chain
B6A42_12775	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B6A42_12800	COG2056	Na+-H+ antiporter family
B6A42_12810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B6A42_12815	COG2716	regulation of RNA biosynthetic process
B6A42_12820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B6A42_12840	COG4783	chaperone-mediated protein folding
B6A42_12845	COG1393	Belongs to the ArsC family
B6A42_12870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B6A42_12895	COG2890	protein-(glutamine-N5) methyltransferase activity
B6A42_12920	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B6A42_12930	COG0012	GTP binding
B6A42_13180	COG4695	Portal protein
B6A42_13265	COG4974	Belongs to the 'phage' integrase family
B6A42_13270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B6A42_13275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B6A42_13285	COG3951	Flagellar rod assembly protein muramidase FlgJ
B6A42_13285	COG1705	Flagellar rod assembly protein muramidase FlgJ
B6A42_13290	COG1706	bacterial-type flagellum-dependent cell motility
B6A42_13295	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
B6A42_13300	COG4786	Flagellar basal body rod
B6A42_13305	COG4787	bacterial-type flagellum-dependent cell motility
B6A42_13310	COG1749	Flagellar hook protein flgE
B6A42_13315	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B6A42_13320	COG1558	bacterial-type flagellum-dependent cell motility
B6A42_13325	COG1815	bacterial-type flagellum-dependent cell motility
B6A42_13330	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B6A42_13335	COG0835	chemotaxis
B6A42_13335	COG0784	Response regulator, receiver
B6A42_13345	COG2747	anti-sigma28 factor FlgM
B6A42_13385	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B6A42_13395	COG2194	sulfuric ester hydrolase activity
B6A42_13465	COG0326	Molecular chaperone. Has ATPase activity
B6A42_13470	COG3710	Transcriptional regulator
B6A42_13490	COG0622	Phosphoesterase
B6A42_13515	COG1090	epimerase
B6A42_13520	COG0300	oxidoreductase activity
B6A42_13525	COG3118	belongs to the thioredoxin family
B6A42_13530	COG0330	HflC and HflK could
B6A42_13555	COG3115	cell septum assembly
B6A42_13560	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
B6A42_13565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B6A42_13570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B6A42_13575	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B6A42_13580	COG2190	(PTS) system
B6A42_13595	COG1702	phosphate starvation-inducible protein PhoH
B6A42_13600	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B6A42_13605	COG4535	Mg2 and Co2 transporter CorC
B6A42_13610	COG0815	Transfers the fatty acyl group on membrane lipoproteins
B6A42_13620	COG0495	leucyl-tRNA aminoacylation
B6A42_13635	COG0799	negative regulation of ribosome biogenesis
B6A42_13645	COG0768	penicillin binding
B6A42_13655	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B6A42_13660	COG1686	Belongs to the peptidase S11 family
B6A42_13675	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B6A42_13690	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B6A42_13700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B6A42_13705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6A42_13735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B6A42_13735	COG1263	PTS System
B6A42_13740	COG1609	Transcriptional regulator
B6A42_13750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B6A42_13755	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B6A42_13760	COG2011	ABC-type metal ion transport system permease component
B6A42_13765	COG1464	Belongs to the NlpA lipoprotein family
B6A42_13775	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
B6A42_13790	COG1720	tRNA m6t6A37 methyltransferase activity
B6A42_13800	COG0121	glutamine amidotransferase
B6A42_13805	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B6A42_13820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B6A42_13830	COG2226	methyltransferase
B6A42_13855	COG0347	Belongs to the P(II) protein family
B6A42_13870	COG0825	malonyl-CoA metabolic process
B6A42_13885	COG0587	DNA-directed DNA polymerase activity
B6A42_13890	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B6A42_13895	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B6A42_13915	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
B6A42_13920	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B6A42_13925	COG0750	zinc metalloprotease
B6A42_13935	COG0575	Belongs to the CDS family
B6A42_13940	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B6A42_13945	COG0233	cytoplasmic translational termination
B6A42_13950	COG0528	UMP kinase activity
B6A42_13960	COG0052	Belongs to the universal ribosomal protein uS2 family
B6A42_13980	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B6A42_13985	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B6A42_14010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B6A42_14010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B6A42_14015	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B6A42_14020	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B6A42_14025	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B6A42_14040	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
B6A42_14045	COG2252	PERMEase
B6A42_14050	COG2195	Cleaves the N-terminal amino acid of tripeptides
B6A42_14055	COG4067	protein conserved in archaea
B6A42_14055	COG0189	ligase activity
B6A42_14060	COG0189	ligase activity
B6A42_14070	COG0733	neurotransmitter:sodium symporter activity
B6A42_14090	COG0514	ATP-dependent DNA helicase (RecQ)
B6A42_14095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B6A42_14100	COG0745	RESPONSE REGULATOR receiver
B6A42_14100	COG3706	GGDEF domain
B6A42_14110	COG1477	protein flavinylation
B6A42_14115	COG2871	sodium ion transport
B6A42_14120	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
B6A42_14135	COG1805	sodium ion transport
B6A42_14140	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
B6A42_14145	COG0271	Belongs to the BolA IbaG family
B6A42_14160	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B6A42_14175	COG1595	DNA-templated transcription, initiation
B6A42_14190	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B6A42_14195	COG0693	protein deglycase activity
B6A42_14205	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B6A42_14215	COG0560	Phosphoserine phosphatase
B6A42_14225	COG0813	purine-nucleoside phosphorylase activity
B6A42_14230	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B6A42_14235	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
B6A42_14250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B6A42_14260	COG3022	response to hydroperoxide
B6A42_14265	COG1115	amino acid carrier protein
B6A42_14285	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B6A42_14295	COG0583	DNA-binding transcription factor activity
B6A42_14310	COG0505	Belongs to the CarA family
B6A42_14320	COG0494	nUDIX hydrolase
B6A42_14325	COG0653	protein targeting
B6A42_14330	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
B6A42_14335	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B6A42_14340	COG0849	cell division
B6A42_14345	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B6A42_14360	COG0772	Belongs to the SEDS family
B6A42_14365	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B6A42_14370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B6A42_14375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B6A42_14380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B6A42_14390	COG3116	cell division
B6A42_14405	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B6A42_14410	COG3107	peptidoglycan biosynthetic process
B6A42_14420	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B6A42_14435	COG0625	glutathione transferase activity
B6A42_14440	COG2857	Cytochrome c1
B6A42_14445	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B6A42_14450	COG0723	plastoquinol--plastocyanin reductase activity
B6A42_14470	COG3105	Protein conserved in bacteria
B6A42_14480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B6A42_14490	COG0187	DNA topoisomerase II activity
B6A42_14495	COG3150	esterase
B6A42_14505	COG3151	Protein conserved in bacteria
B6A42_14510	COG0494	nUDIX hydrolase
B6A42_14515	COG1538	Outer membrane efflux protein
B6A42_14525	COG5002	protein histidine kinase activity
B6A42_14525	COG2198	Histidine kinase
B6A42_14525	COG0784	Response regulator, receiver
B6A42_14535	COG1242	4 iron, 4 sulfur cluster binding
B6A42_14540	COG0067	glutamate synthase
B6A42_14540	COG0070	glutamate synthase
B6A42_14540	COG0069	glutamate synthase activity
B6A42_14555	COG0493	'glutamate synthase
B6A42_14580	COG0195	Participates in both transcription termination and antitermination
B6A42_14585	COG0779	Required for maturation of 30S ribosomal subunits
B6A42_14600	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B6A42_14605	COG3153	acetyltransferase
B6A42_14630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B6A42_14635	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B6A42_14645	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B6A42_14650	COG0513	Belongs to the DEAD box helicase family
B6A42_14675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B6A42_14680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B6A42_14690	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
B6A42_14695	COG1534	Rna-binding protein
B6A42_14700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B6A42_14705	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B6A42_14725	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B6A42_14755	COG0628	permease
B6A42_14760	COG2813	Specifically methylates the guanine in position
B6A42_14770	COG0747	negative chemotaxis
B6A42_14785	COG0444	Belongs to the ABC transporter superfamily
B6A42_14790	COG4608	Belongs to the ABC transporter superfamily
B6A42_14815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B6A42_14820	COG3842	ATPase activity
B6A42_14830	COG1840	ABC-type Fe3 transport system, periplasmic component
B6A42_14835	COG0004	ammonium transporteR
B6A42_14855	COG1752	Esterase of the alpha-beta hydrolase superfamily
B6A42_14865	COG1643	Atp-dependent helicase
B6A42_14875	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B6A42_14890	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B6A42_14905	COG0842	Transport permease protein
B6A42_14915	COG0659	secondary active sulfate transmembrane transporter activity
B6A42_14920	COG0288	reversible hydration of carbon dioxide
B6A42_14935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B6A42_14940	COG0508	dehydrogenase complex catalyzes the overall conversion of
B6A42_14945	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B6A42_14950	COG2186	Transcriptional regulator
B6A42_14955	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B6A42_14960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B6A42_14970	COG0716	FMN binding
B6A42_14980	COG0157	Belongs to the NadC ModD family
B6A42_14985	COG4969	Belongs to the N-Me-Phe pilin family
B6A42_14995	COG1459	type II secretion system
B6A42_15005	COG0237	dephospho-CoA kinase activity
B6A42_15010	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
B6A42_15015	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
B6A42_15025	COG0336	Belongs to the RNA methyltransferase TrmD family
B6A42_15035	COG0228	four-way junction DNA binding
B6A42_15040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B6A42_15045	COG4137	Cytochrome C assembly protein
B6A42_15050	COG4536	flavin adenine dinucleotide binding
B6A42_15055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B6A42_15060	COG4942	peptidase
B6A42_15060	COG1388	LysM domain
B6A42_15075	COG0585	pseudouridine synthase activity
B6A42_15085	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B6A42_15090	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B6A42_15105	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B6A42_15110	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B6A42_15115	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B6A42_15125	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B6A42_15130	COG1610	YqeY-like protein
B6A42_15135	COG0358	DNA primase activity
B6A42_15140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B6A42_15150	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B6A42_15155	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B6A42_15160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B6A42_15180	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B6A42_15195	COG3610	response to peptide
B6A42_15200	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B6A42_15205	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B6A42_15210	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B6A42_15215	COG0142	geranyltranstransferase activity
B6A42_15225	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B6A42_15245	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B6A42_15250	COG1349	DNA-binding transcription factor activity
B6A42_15255	COG0469	pyruvate kinase activity
B6A42_15275	COG0583	DNA-binding transcription factor activity
B6A42_15285	COG0442	prolyl-tRNA aminoacylation
B6A42_15290	COG0668	transmembrane transport
B6A42_15295	COG0191	fructose-bisphosphate aldolase activity
B6A42_15310	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B6A42_15315	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B6A42_15325	COG3091	SprT-like family
B6A42_15335	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B6A42_15340	COG0189	ligase activity
B6A42_15350	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B6A42_15365	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B6A42_15370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B6A42_15375	COG0762	integral membrane protein
B6A42_15395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B6A42_15400	COG2066	Belongs to the glutaminase family
B6A42_15405	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B6A42_15415	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
B6A42_15475	COG0312	modulator of DNA gyrase
B6A42_15480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B6A42_15490	COG1530	ribonuclease E activity
B6A42_15495	COG0424	maF-like protein
B6A42_15500	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B6A42_15505	COG1792	Involved in formation and maintenance of cell shape
B6A42_15510	COG1077	Cell shape determining protein MreB Mrl
B6A42_15555	COG1459	type II secretion system
B6A42_15560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B6A42_15595	COG2199	diguanylate cyclase activity
B6A42_15595	COG2200	EAL domain
B6A42_15600	COG0629	single-stranded DNA binding
B6A42_15615	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B6A42_15625	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B6A42_15630	COG0527	aspartate kinase activity
B6A42_15635	COG0312	modulator of DNA gyrase
B6A42_15640	COG3028	Belongs to the UPF0307 family
B6A42_15650	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
B6A42_15655	COG1178	ABC-type Fe3 transport system permease component
B6A42_15665	COG0163	prenyltransferase activity
B6A42_15670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B6A42_15700	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B6A42_15710	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
B6A42_15725	COG1136	(ABC) transporter
B6A42_15750	COG0432	Pfam Uncharacterised protein family UPF0047
B6A42_15760	COG0305	Participates in initiation and elongation during chromosome replication
B6A42_15790	COG2906	2 iron, 2 sulfur cluster binding
B6A42_15800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B6A42_15805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B6A42_15810	COG0049	tRNA binding
B6A42_15820	COG2168	tRNA wobble position uridine thiolation
B6A42_15825	COG2923	Belongs to the DsrF TusC family
B6A42_15835	COG2964	Protein conserved in bacteria
B6A42_15840	COG0545	Peptidyl-prolyl cis-trans isomerase
B6A42_15855	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
B6A42_15860	COG0330	HflC and HflK could
B6A42_15865	COG0330	HflC and HflK could
B6A42_15870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B6A42_15885	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B6A42_15895	COG0802	atpase or kinase
B6A42_15955	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
B6A42_15960	COG1162	GTPase activity
B6A42_15965	COG0688	phosphatidylethanolamine metabolic process
B6A42_15975	COG0840	transmembrane signaling receptor activity
B6A42_15990	COG4942	peptidase
B6A42_16010	COG2816	NAD+ diphosphatase activity
B6A42_16015	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
B6A42_16025	COG0085	RNA polymerase activity
B6A42_16035	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B6A42_16050	COG0250	Participates in transcription elongation, termination and antitermination
B6A42_16055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B6A42_16065	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B6A42_16090	COG1072	(Pantothenic acid kinase))
B6A42_16105	COG0149	triose-phosphate isomerase activity
B6A42_16110	COG0534	Mate efflux family protein
B6A42_16115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B6A42_16120	COG1575	Belongs to the MenA family. Type 1 subfamily
B6A42_16125	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B6A42_16130	COG1509	lysine 2,3-aminomutase activity
B6A42_16140	COG1285	pathogenesis
B6A42_16145	COG0205	6-phosphofructokinase activity
B6A42_16155	COG3678	ATP-independent chaperone mediated protein folding
B6A42_16160	COG0745	RESPONSE REGULATOR receiver
B6A42_16165	COG2205	protein histidine kinase activity
B6A42_16170	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B6A42_16175	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B6A42_16180	COG0180	Tryptophanyl-tRNA synthetase
B6A42_16185	COG0546	phosphoglycolate phosphatase activity
B6A42_16190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B6A42_16195	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B6A42_16240	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B6A42_16250	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B6A42_16250	COG0678	peroxiredoxin activity
B6A42_16260	COG0251	oxidation-reduction process
B6A42_16275	COG0137	argininosuccinate synthase activity
B6A42_16285	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B6A42_16400	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B6A42_16435	COG0534	Mate efflux family protein
B6A42_16445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B6A42_16450	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B6A42_16455	COG2937	Belongs to the GPAT DAPAT family
B6A42_16460	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B6A42_16465	COG3161	chorismate lyase activity
B6A42_16470	COG1580	Controls the rotational direction of flagella during chemotaxis
B6A42_16485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B6A42_16490	COG2177	Part of the ABC transporter FtsEX involved in
B6A42_16495	COG2884	Cell division ATP-binding protein ftsE
B6A42_16500	COG0552	protein localization to endoplasmic reticulum
B6A42_16505	COG0742	ribosomal rna small subunit methyltransferase
B6A42_16515	COG2095	MarC family integral membrane protein
B6A42_16555	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B6A42_16560	COG0640	Transcriptional regulator
B6A42_16565	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
B6A42_16570	COG1280	lysine exporter protein (LysE YggA)
B6A42_16580	COG0561	phosphatase activity
B6A42_16600	COG2199	diguanylate cyclase activity
B6A42_16600	COG2200	EAL domain
B6A42_16600	COG3287	FIST C domain
B6A42_16605	COG1011	Hydrolase
B6A42_16610	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B6A42_16620	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B6A42_16625	COG0019	diaminopimelate decarboxylase activity
B6A42_16635	COG1965	Belongs to the frataxin family
B6A42_16640	COG3072	Adenylate cyclase
B6A42_16650	COG1587	Uroporphyrinogen-III synthase
B6A42_16655	COG2959	enzyme of heme biosynthesis
B6A42_16720	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B6A42_16730	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B6A42_16735	COG3118	belongs to the thioredoxin family
B6A42_16745	COG0248	Ppx GppA phosphatase
B6A42_16750	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B6A42_16760	COG0514	ATP-dependent DNA helicase (RecQ)
B6A42_16775	COG1280	lysine exporter protein (LysE YggA)
B6A42_16810	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
B6A42_16815	COG1028	Short-chain dehydrogenase reductase Sdr
B6A42_16825	COG1024	Enoyl-CoA hydratase
B6A42_16830	COG1024	Enoyl-CoA hydratase
B6A42_16855	COG1960	acyl-CoA dehydrogenase activity
B6A42_16860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B6A42_16895	COG2259	Doxx family
B6A42_16900	COG1741	Belongs to the pirin family
B6A42_16915	COG1115	amino acid carrier protein
B6A42_16920	COG0583	DNA-binding transcription factor activity
B6A42_17000	COG0583	DNA-binding transcription factor activity
B6A42_17005	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B6A42_17030	COG2176	DNA-directed DNA polymerase activity
B6A42_17035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B6A42_17040	COG1846	Transcriptional regulator
B6A42_17045	COG3706	GGDEF domain
B6A42_17075	COG2425	protein containing a von Willebrand factor type A (vWA) domain
B6A42_17080	COG0714	Associated with various cellular activities
B6A42_17085	COG0494	nUDIX hydrolase
B6A42_17095	COG1028	Short-chain dehydrogenase reductase Sdr
B6A42_17125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B6A42_17130	COG0835	chemotaxis
B6A42_17130	COG0784	Response regulator, receiver
B6A42_17135	COG3706	GGDEF domain
B6A42_17160	COG1760	l-serine dehydratase
B6A42_17165	COG0583	DNA-binding transcription factor activity
B6A42_17170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B6A42_17205	COG3842	ATPase activity
B6A42_17220	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B6A42_17255	COG1011	Hydrolase
B6A42_17265	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
B6A42_17270	COG1454	alcohol dehydrogenase
B6A42_17320	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B6A42_17370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B6A42_17375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B6A42_17395	COG0784	Response regulator, receiver
B6A42_17395	COG2205	protein histidine kinase activity
B6A42_17400	COG2205	protein histidine kinase activity
B6A42_17400	COG0784	Response regulator, receiver
B6A42_17475	COG1063	alcohol dehydrogenase
B6A42_17480	COG0156	8-amino-7-oxononanoate synthase activity
B6A42_17485	COG2200	EAL domain
B6A42_17485	COG2202	Pas domain
B6A42_17485	COG2199	diguanylate cyclase activity
B6A42_17505	COG0346	lactoylglutathione lyase activity
B6A42_17510	COG1028	Short-chain dehydrogenase reductase Sdr
B6A42_17525	COG2205	protein histidine kinase activity
B6A42_17540	COG0667	Aldo Keto reductase
B6A42_17545	COG0583	DNA-binding transcription factor activity
B6A42_17560	COG0714	Associated with various cellular activities
B6A42_17580	COG2304	oxidoreductase activity
B6A42_17600	COG0110	maltose O-acetyltransferase activity
B6A42_17605	COG1765	OsmC-like protein
B6A42_17610	COG0673	inositol 2-dehydrogenase activity
B6A42_17630	COG0531	amino acid
B6A42_17650	COG2205	protein histidine kinase activity
B6A42_17685	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B6A42_17690	COG0402	S-adenosylhomocysteine deaminase activity
B6A42_17695	COG0861	Integral membrane protein TerC family
B6A42_17750	COG1175	transmembrane transport
B6A42_17765	COG3842	ATPase activity
B6A42_17770	COG2096	Adenosyltransferase
B6A42_17775	COG0748	coenzyme F420 binding
B6A42_17780	COG3721	Heme iron utilization protein
B6A42_17790	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
B6A42_17795	COG0811	peptide transport
B6A42_17800	COG0848	biopolymer transport protein
B6A42_17815	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
B6A42_17820	COG2814	Major facilitator Superfamily
B6A42_17830	COG0739	heme binding
B6A42_17845	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B6A42_17855	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
B6A42_17865	COG0513	Belongs to the DEAD box helicase family
B6A42_17875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B6A42_17875	COG4191	Histidine kinase
B6A42_17880	COG0784	Response regulator, receiver
B6A42_17880	COG3437	response regulator, receiver
B6A42_17885	COG1609	Transcriptional regulator
B6A42_17890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B6A42_17895	COG1879	ABC-type sugar transport system periplasmic component
B6A42_17900	COG1172	Belongs to the binding-protein-dependent transport system permease family
B6A42_17905	COG1129	ABC transporter
B6A42_17910	COG1869	D-ribose catabolic process
B6A42_17920	COG3469	chitinase activity
B6A42_17935	COG0004	ammonium transporteR
B6A42_17980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B6A42_17985	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
B6A42_18075	COG1609	Transcriptional regulator
B6A42_18080	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B6A42_18085	COG3265	gluconokinase activity
B6A42_18100	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B6A42_18125	COG0583	DNA-binding transcription factor activity
B6A42_18145	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B6A42_18155	COG0668	transmembrane transport
B6A42_18175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B6A42_18215	COG3118	belongs to the thioredoxin family
B6A42_18235	COG1280	lysine exporter protein (LysE YggA)
B6A42_18270	COG0583	DNA-binding transcription factor activity
B6A42_18280	COG4948	Mandelate Racemase Muconate Lactonizing
B6A42_18285	COG1396	sequence-specific DNA binding
B6A42_18290	COG5001	Diguanylate cyclase
B6A42_18300	COG3706	GGDEF domain
B6A42_18310	COG0642	Histidine kinase
B6A42_18315	COG0745	RESPONSE REGULATOR receiver
B6A42_18330	COG2130	NADP-dependent
B6A42_18385	COG0366	Alpha amylase catalytic
B6A42_18415	COG3279	Response regulator of the LytR AlgR family
B6A42_18420	COG3275	phosphorelay sensor kinase activity
B6A42_18435	COG4591	ABC-type transport system involved in lipoprotein release permease component
B6A42_18440	COG1136	(ABC) transporter
B6A42_18475	COG3530	Putative quorum-sensing-regulated virulence factor
B6A42_18490	COG1686	Belongs to the peptidase S11 family
B6A42_18510	COG3036	rescue of stalled ribosome
B6A42_18515	COG1278	Cold shock
B6A42_18530	COG1017	nitric oxide dioxygenase activity
B6A42_18530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B6A42_18535	COG3604	Transcriptional regulator
B6A42_18545	COG0546	phosphoglycolate phosphatase activity
B6A42_18550	COG2249	NAD(P)H dehydrogenase (quinone) activity
B6A42_18585	COG2814	Major facilitator Superfamily
B6A42_18685	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B6A42_18690	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B6A42_18695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B6A42_18700	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B6A42_18715	COG4989	oxidoreductase activity
B6A42_18725	COG0366	Alpha amylase catalytic
B6A42_18735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B6A42_18740	COG1126	abc transporter atp-binding protein
B6A42_18745	COG0765	amino acid transport
B6A42_18755	COG0765	amino acid transport
B6A42_18760	COG0109	protoheme IX farnesyltransferase activity
B6A42_18790	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
B6A42_18795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B6A42_18800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B6A42_18810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B6A42_18850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B6A42_18875	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B6A42_18890	COG1741	Belongs to the pirin family
B6A42_18900	COG2814	Major facilitator Superfamily
B6A42_18905	COG1686	Belongs to the peptidase S11 family
B6A42_18910	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B6A42_18915	COG0583	DNA-binding transcription factor activity
B6A42_18950	COG1253	flavin adenine dinucleotide binding
B6A42_18995	COG0583	DNA-binding transcription factor activity
B6A42_19055	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B6A42_19070	COG2988	succinylglutamate desuccinylase activity
B6A42_19115	COG1846	Transcriptional regulator
B6A42_19140	COG1176	ABC-type spermidine putrescine transport system, permease component I
B6A42_19150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B6A42_19155	COG2423	ornithine cyclodeaminase activity
B6A42_19170	COG3938	Belongs to the proline racemase family
B6A42_19200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B6A42_19215	COG0006	proline dipeptidase activity
B6A42_19280	COG3568	Endonuclease Exonuclease Phosphatase
B6A42_19290	COG3291	Pkd domain containing protein
B6A42_19295	COG0513	Belongs to the DEAD box helicase family
B6A42_19305	COG1376	ErfK ybiS ycfS ynhG family protein
B6A42_19305	COG1388	LysM domain
B6A42_19315	COG0789	Transcriptional regulator
B6A42_19320	COG3272	Protein of unknown function (DUF1722)
B6A42_19325	COG0813	purine-nucleoside phosphorylase activity
B6A42_19340	COG3706	GGDEF domain
B6A42_19355	COG1566	PFAM secretion protein HlyD family protein
B6A42_19360	COG0786	glutamate:sodium symporter activity
B6A42_19370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B6A42_19385	COG0583	DNA-binding transcription factor activity
B6A42_19395	COG1132	(ABC) transporter
B6A42_19440	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B6A42_19450	COG0259	pyridoxamine-phosphate oxidase activity
B6A42_19485	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
B6A42_19490	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B6A42_19495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B6A42_19505	COG1999	signal sequence binding
B6A42_19520	COG1671	Belongs to the UPF0178 family
B6A42_19525	COG0393	Putative heavy-metal-binding
B6A42_19530	COG0583	DNA-binding transcription factor activity
B6A42_19565	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B6A42_19775	COG1301	dicarboxylic acid transport
B6A42_19800	COG2207	Transcriptional regulator
B6A42_19860	COG5001	Diguanylate cyclase
B6A42_19860	COG5002	protein histidine kinase activity
B6A42_19865	COG3070	regulator of competence-specific genes
B6A42_19895	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B6A42_19910	COG3437	response regulator, receiver
B6A42_19910	COG3850	Histidine kinase
B6A42_19910	COG2205	protein histidine kinase activity
B6A42_19910	COG4999	Histidine kinase
B6A42_19915	COG0745	RESPONSE REGULATOR receiver
B6A42_19920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6A42_19930	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B6A42_19955	COG0745	RESPONSE REGULATOR receiver
B6A42_19965	COG0471	metal ion transport
B6A42_20005	COG1595	DNA-templated transcription, initiation
B6A42_20025	COG0251	oxidation-reduction process
B6A42_20035	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B6A42_20035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B6A42_20050	COG1063	alcohol dehydrogenase
B6A42_20070	COG0583	DNA-binding transcription factor activity
B6A42_20090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B6A42_20100	COG1175	transmembrane transport
B6A42_20125	COG0438	transferase activity, transferring glycosyl groups
B6A42_20135	COG0671	phosphoesterase, PA-phosphatase related
B6A42_20145	COG3708	Transcriptional regulator
B6A42_20145	COG2207	Transcriptional regulator
B6A42_20160	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B6A42_20165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B6A42_20175	COG1116	anion transmembrane transporter activity
B6A42_20185	COG0656	L-ascorbic acid biosynthetic process
B6A42_20205	COG0583	DNA-binding transcription factor activity
B6A42_20230	COG0768	penicillin binding
B6A42_20235	COG2723	6-phospho-beta-galactosidase activity
B6A42_20245	COG0589	response to stress
B6A42_20250	COG3842	ATPase activity
B6A42_20255	COG0546	phosphoglycolate phosphatase activity
B6A42_20275	COG1175	transmembrane transport
B6A42_20280	COG0583	DNA-binding transcription factor activity
B6A42_20350	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B6A42_20370	COG3706	GGDEF domain
B6A42_20370	COG0745	RESPONSE REGULATOR receiver
B6A42_20395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B6A42_20420	COG0745	RESPONSE REGULATOR receiver
B6A42_20430	COG0840	transmembrane signaling receptor activity
B6A42_20435	COG1444	tRNA N-acetyltransferase activity
B6A42_20465	COG4608	Belongs to the ABC transporter superfamily
B6A42_20470	COG0444	Belongs to the ABC transporter superfamily
B6A42_20510	COG1028	Short-chain dehydrogenase reductase Sdr
B6A42_20520	COG1028	Short-chain dehydrogenase reductase Sdr
B6A42_20525	COG1733	regulation of RNA biosynthetic process
B6A42_20545	COG0583	DNA-binding transcription factor activity
B6A42_20550	COG1051	belongs to the nudix hydrolase family
B6A42_20565	COG5001	Diguanylate cyclase
B6A42_20565	COG3300	MHYT domain
B6A42_20570	COG0697	spore germination
B6A42_20575	COG1846	Transcriptional regulator
B6A42_20605	COG1288	antiporter activity
B6A42_20610	COG0583	DNA-binding transcription factor activity
B6A42_20620	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B6A42_20625	COG3960	tartronate-semialdehyde synthase activity
B6A42_20630	COG3622	Belongs to the hyi family
B6A42_20635	COG2084	Dehydrogenase
B6A42_20685	COG0831	urea catabolic process
B6A42_20690	COG0832	Belongs to the urease beta subunit family
B6A42_20695	COG0804	urea catabolic process
B6A42_20700	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
B6A42_20710	COG0830	nickel cation binding
B6A42_20745	COG0840	transmembrane signaling receptor activity
B6A42_20765	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
B6A42_20780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B6A42_20785	COG0800	Aldolase
B6A42_20805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B6A42_20810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B6A42_20815	COG1845	cytochrome c oxidase, subunit III
B6A42_20820	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B6A42_20825	COG0109	protoheme IX farnesyltransferase activity
B6A42_20845	COG3179	chitinase
B6A42_20875	COG0583	DNA-binding transcription factor activity
B6A42_20900	COG3214	Protein conserved in bacteria
B6A42_20905	COG0596	Alpha beta hydrolase
B6A42_20940	COG4266	Belongs to the allantoicase family
B6A42_20955	COG0840	transmembrane signaling receptor activity
B6A42_20975	COG2205	protein histidine kinase activity
B6A42_20975	COG0784	Response regulator, receiver
B6A42_20975	COG5002	protein histidine kinase activity
B6A42_20980	COG2226	methyltransferase
B6A42_20985	COG0402	S-adenosylhomocysteine deaminase activity
B6A42_20995	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B6A42_21005	COG2186	Transcriptional regulator
B6A42_21035	COG1278	Cold shock
B6A42_21040	COG3795	YCII-related domain
B6A42_21070	COG1404	Belongs to the peptidase S8 family
B6A42_21125	COG2909	trisaccharide binding
B6A42_21130	COG0058	SHG alpha-glucan phosphorylase activity
B6A42_21135	COG1640	4-alpha-glucanotransferase
B6A42_21140	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B6A42_21145	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B6A42_21160	COG1132	(ABC) transporter
B6A42_21190	COG1619	proteins homologs of microcin C7 resistance protein MccF
B6A42_21295	COG0561	phosphatase activity
B6A42_21305	COG0024	Methionine aminopeptidase
B6A42_21375	COG4771	TonB-dependent receptor
B6A42_21380	COG1917	Cupin 2, conserved barrel domain protein
B6A42_21380	COG4977	sequence-specific DNA binding
B6A42_21400	COG1733	regulation of RNA biosynthetic process
B6A42_21445	COG1414	Transcriptional regulator
B6A42_21480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B6A42_21485	COG0383	alpha-mannosidase activity
B6A42_21490	COG0366	Alpha amylase catalytic
B6A42_21495	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B6A42_21495	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B6A42_21495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B6A42_21510	COG2814	Major facilitator Superfamily
B6A42_21515	COG1120	ATPase activity
B6A42_21555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B6A42_21565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B6A42_21575	COG0662	Cupin 2, conserved barrel domain protein
B6A42_21585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B6A42_21590	COG2076	Multidrug Resistance protein
B6A42_21595	COG2076	Multidrug Resistance protein
B6A42_21600	COG0590	tRNA wobble adenosine to inosine editing
B6A42_21615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B6A42_21660	COG4175	Glycine betaine
B6A42_21660	COG3448	diguanylate cyclase activity
B6A42_21665	COG4176	ABC-type proline glycine betaine transport system permease component
B6A42_21705	COG0583	DNA-binding transcription factor activity
B6A42_21730	COG4964	Belongs to the GSP D family
B6A42_21740	COG2894	cell division
B6A42_21795	COG1477	protein flavinylation
B6A42_21825	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B6A42_21835	COG0581	inorganic phosphate transmembrane transporter activity
B6A42_21855	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
B6A42_21860	COG1162	GTPase activity
B6A42_21885	COG4720	Psort location CytoplasmicMembrane, score
B6A42_21890	COG0363	glucosamine-6-phosphate deaminase activity
B6A42_21905	COG0454	-acetyltransferase
B6A42_21910	COG0840	transmembrane signaling receptor activity
B6A42_21940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B6A42_21945	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B6A42_21950	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
B6A42_21960	COG1522	sequence-specific DNA binding
B6A42_21995	COG1288	antiporter activity
B6A42_22085	COG0583	DNA-binding transcription factor activity
B6A42_22100	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B6A42_22140	COG3046	protein related to deoxyribodipyrimidine photolyase
B6A42_22150	COG2329	Antibiotic biosynthesis monooxygenase
B6A42_22165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B6A42_22175	COG0583	DNA-binding transcription factor activity
B6A42_22180	COG1234	tRNA 3'-trailer cleavage
B6A42_22215	COG3437	response regulator, receiver
B6A42_22220	COG3383	formate dehydrogenase (NAD+) activity
B6A42_22235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B6A42_22260	COG0739	heme binding
B6A42_22290	COG0300	oxidoreductase activity
B6A42_22295	COG5553	Cysteine dioxygenase type I
B6A42_22310	COG0673	inositol 2-dehydrogenase activity
B6A42_22345	COG4191	Histidine kinase
B6A42_22345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B6A42_22350	COG1132	(ABC) transporter
B6A42_22370	COG0625	glutathione transferase activity
B6A42_22390	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B6A42_22405	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B6A42_22420	COG4580	involved in the transport of maltose and maltodextrins
B6A42_22430	COG0840	transmembrane signaling receptor activity
B6A42_22495	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B6A42_22505	COG0415	Belongs to the DNA photolyase family
B6A42_22550	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B6A42_22550	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B6A42_22560	COG2207	Transcriptional regulator
B6A42_22560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B6A42_22565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B6A42_22585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B6A42_22600	COG1522	sequence-specific DNA binding
B6A42_22625	COG1357	PFAM Pentapeptide repeats (8 copies)
B6A42_22635	COG1294	oxidase, subunit
B6A42_22640	COG1271	oxidase subunit
B6A42_22645	COG1805	sodium ion transport
B6A42_22670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B6A42_22705	COG4943	cyclic-guanylate-specific phosphodiesterase activity
B6A42_22765	COG1309	transcriptional regulator
B6A42_22785	COG0745	RESPONSE REGULATOR receiver
B6A42_22790	COG5002	protein histidine kinase activity
B6A42_22825	COG0842	Transport permease protein
B6A42_22830	COG1131	(ABC) transporter
B6A42_22875	COG0110	maltose O-acetyltransferase activity
B6A42_22885	COG0625	glutathione transferase activity
B6A42_22890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B6A42_22900	COG0366	Alpha amylase catalytic
B6A42_22935	COG0625	glutathione transferase activity
B6A42_22940	COG2130	NADP-dependent
B6A42_22945	COG1309	transcriptional regulator
B6A42_22955	COG0583	DNA-binding transcription factor activity
B6A42_22960	COG0583	DNA-binding transcription factor activity
B6A42_22965	COG3706	GGDEF domain
B6A42_22985	COG0513	Belongs to the DEAD box helicase family
B6A42_22995	COG3447	MASE1 domain protein
B6A42_22995	COG5001	Diguanylate cyclase
B6A42_22995	COG5002	protein histidine kinase activity
B6A42_23025	COG2204	response regulator
B6A42_23040	COG0573	inorganic phosphate transmembrane transporter activity
B6A42_23050	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B6A42_23065	COG2815	serine threonine protein kinase
B6A42_23065	COG0515	serine threonine protein kinase
B6A42_23145	COG0583	DNA-binding transcription factor activity
B6A42_23150	COG2814	Major facilitator Superfamily
B6A42_23175	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B6A42_23185	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B6A42_23195	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B6A42_23205	COG0579	oxidoreductase
B6A42_23235	COG1012	belongs to the aldehyde dehydrogenase family
B6A42_23240	COG3284	Transcriptional regulator
B6A42_23260	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B6A42_23265	COG0363	glucosamine-6-phosphate deaminase activity
B6A42_23270	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B6A42_23275	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B6A42_23295	COG2271	Major facilitator Superfamily
B6A42_23300	COG3851	Histidine kinase
B6A42_23305	COG2197	response regulator
B6A42_23330	COG3217	Mosc domain protein beta barrel domain protein
B6A42_23330	COG0633	Ferredoxin
B6A42_23330	COG0633	Ferredoxin
B6A42_23330	COG3217	Mosc domain protein beta barrel domain protein
B6A42_23365	COG2354	Protein conserved in bacteria
B6A42_23375	COG0366	Alpha amylase catalytic
B6A42_23410	COG0840	transmembrane signaling receptor activity
B6A42_23425	COG2172	sigma factor antagonist activity
B6A42_23435	COG3437	response regulator, receiver
B6A42_23455	COG0516	GMP reductase activity
B6A42_23520	COG0242	peptide deformylase activity
B6A42_23580	COG4208	sulfate ABC transporter
B6A42_23590	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
B6A42_23600	COG3604	Transcriptional regulator
B6A42_23630	COG1196	nuclear chromosome segregation
B6A42_23650	COG1278	Cold shock
B6A42_23690	COG0741	lytic transglycosylase activity
B6A42_23700	COG4974	Belongs to the 'phage' integrase family
B6A42_23725	COG1132	(ABC) transporter
B6A42_23740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B6A42_23815	COG1278	Cold shock
B6A42_23820	COG4974	Belongs to the 'phage' integrase family
B6A42_23955	COG0516	GMP reductase activity
B6A42_23995	COG1404	Belongs to the peptidase S8 family
B6A42_24010	COG1309	transcriptional regulator
B6A42_24035	COG4175	Glycine betaine
B6A42_24035	COG3448	diguanylate cyclase activity
B6A42_24055	COG1304	FMN binding
B6A42_24060	COG1620	l-lactate permease
B6A42_24065	COG0583	DNA-binding transcription factor activity
B6A42_24080	COG1067	ATP-dependent peptidase activity
B6A42_24090	COG0840	transmembrane signaling receptor activity
B6A42_24105	COG4166	transmembrane transport
B6A42_24110	COG4174	ABC transporter (Permease)
B6A42_24115	COG4239	(ABC) transporter, permease
B6A42_24130	COG0745	RESPONSE REGULATOR receiver
B6A42_24130	COG3706	GGDEF domain
B6A42_24170	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B6A42_24175	COG4605	iron ion homeostasis
B6A42_24180	COG4604	ABC transporter, ATP-binding protein
B6A42_24185	COG2759	Belongs to the formate--tetrahydrofolate ligase family
B6A42_24200	COG0004	ammonium transporteR
B6A42_24210	COG2271	Major facilitator Superfamily
B6A42_24225	COG2199	diguanylate cyclase activity
B6A42_24225	COG2203	Gaf domain
B6A42_24235	COG0739	heme binding
B6A42_24270	COG3501	Rhs element vgr protein
B6A42_24295	COG2815	serine threonine protein kinase
B6A42_24295	COG0515	serine threonine protein kinase
B6A42_24330	COG1522	sequence-specific DNA binding
B6A42_24375	COG1309	transcriptional regulator
B6A42_24380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6A42_24385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6A42_24400	COG0183	Belongs to the thiolase family
B6A42_24415	COG1794	racemase activity, acting on amino acids and derivatives
B6A42_24430	COG4412	M6 family metalloprotease domain protein
B6A42_24430	COG3291	Pkd domain containing protein
B6A42_24480	COG0602	queuosine metabolic process
B6A42_24490	COG0189	ligase activity
B6A42_24490	COG4067	protein conserved in archaea
B6A42_24500	COG0545	Peptidyl-prolyl cis-trans isomerase
B6A42_24535	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B6A42_24540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B6A42_24565	COG2827	Endonuclease containing a URI domain
B6A42_24580	COG5002	protein histidine kinase activity
B6A42_24580	COG0784	Response regulator, receiver
B6A42_24645	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B6A42_24655	COG4181	ATPase activity
B6A42_24680	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B6A42_24685	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B6A42_24695	COG3005	denitrification pathway
B6A42_24705	COG0243	molybdopterin cofactor binding
B6A42_24715	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B6A42_24720	COG3850	Histidine kinase
B6A42_24725	COG2197	response regulator
B6A42_24730	COG3069	C4-dicarboxylate transmembrane transporter activity
B6A42_24750	COG3038	cytochrome b561
B6A42_24755	COG2353	YceI-like domain
B6A42_24775	COG3593	DNA synthesis involved in DNA repair
B6A42_24810	COG1605	Chorismate mutase
B6A42_24835	COG0745	RESPONSE REGULATOR receiver
B6A42_24840	COG0784	Response regulator, receiver
B6A42_24840	COG2205	protein histidine kinase activity
B6A42_24845	COG0840	transmembrane signaling receptor activity
B6A42_24850	COG3070	regulator of competence-specific genes
B6A42_24855	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B6A42_24875	COG2050	protein possibly involved in aromatic compounds catabolism
B6A42_24895	COG4771	TonB-dependent receptor
B6A42_24895	COG1629	transport
B6A42_24900	COG0583	DNA-binding transcription factor activity
B6A42_24905	COG1042	CoA-binding domain protein
B6A42_24905	COG0045	succinate-CoA ligase (ADP-forming) activity
B6A42_24905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B6A42_24910	COG3266	domain, Protein
B6A42_24930	COG0023	Translation Initiation Factor
B6A42_25085	COG0745	RESPONSE REGULATOR receiver
B6A42_25095	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
B6A42_25100	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
B6A42_25115	COG3706	GGDEF domain
B6A42_25135	COG4149	molybdate abc transporter
B6A42_25165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B6A42_25165	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B6A42_25170	COG1105	Belongs to the carbohydrate kinase PfkB family
B6A42_25175	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
B6A42_25175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B6A42_25175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B6A42_25190	COG2207	Transcriptional regulator
B6A42_25195	COG1979	alcohol dehydrogenase
B6A42_25210	COG0784	Response regulator, receiver
B6A42_25210	COG2198	Histidine kinase
B6A42_25210	COG2205	protein histidine kinase activity
B6A42_25220	COG1803	Methylglyoxal synthase
B6A42_25225	COG2188	Transcriptional regulator
B6A42_25245	COG0800	Aldolase
B6A42_25270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B6A42_25275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B6A42_25280	COG0840	transmembrane signaling receptor activity
B6A42_25285	COG0583	DNA-binding transcription factor activity
B6A42_25290	COG3048	D-serine ammonia-lyase activity
B6A42_25300	COG0346	lactoylglutathione lyase activity
B6A42_25315	COG0456	acetyltransferase
B6A42_25315	COG1214	PFAM Peptidase M22, glycoprotease
B6A42_25345	COG0513	Belongs to the DEAD box helicase family
B6A42_25355	COG0814	amino acid
B6A42_25360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B6A42_25360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B6A42_25385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B6A42_25395	COG2897	thiosulfate sulfurtransferase activity
B6A42_25420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B6A42_25425	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B6A42_25430	COG1522	sequence-specific DNA binding
B6A42_25450	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B6A42_25455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B6A42_25460	COG1473	amidohydrolase
B6A42_25470	COG1522	sequence-specific DNA binding
B6A42_25505	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B6A42_25520	COG0523	cobalamin synthesis protein
B6A42_25535	COG0156	8-amino-7-oxononanoate synthase activity
B6A42_25540	COG2205	protein histidine kinase activity
B6A42_25540	COG0784	Response regulator, receiver
B6A42_25555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B6A42_25585	COG2146	nitrite reductase [NAD(P)H] activity
B6A42_25595	COG1116	anion transmembrane transporter activity
B6A42_25600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B6A42_25615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B6A42_25625	COG0243	molybdopterin cofactor binding
B6A42_25670	COG2315	Protein conserved in bacteria
B6A42_25680	COG2199	diguanylate cyclase activity
B6A42_25680	COG2203	Gaf domain
B6A42_25705	COG3706	GGDEF domain
B6A42_25790	COG2200	EAL domain
B6A42_25790	COG2199	diguanylate cyclase activity
B6A42_25800	COG2267	carboxylic ester hydrolase activity
B6A42_25830	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B6A42_25835	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B6A42_25870	COG0305	Participates in initiation and elongation during chromosome replication
B6A42_26040	COG1280	lysine exporter protein (LysE YggA)
B6A42_26135	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B6A42_26140	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
B6A42_26160	COG1181	Belongs to the D-alanine--D-alanine ligase family
B6A42_26305	COG0561	phosphatase activity
B6A42_26400	COG0583	DNA-binding transcription factor activity
B6A42_26420	COG0604	alcohol dehydrogenase
B6A42_26435	COG0702	epimerase
B6A42_26450	COG0583	DNA-binding transcription factor activity
B6A42_26455	COG1028	Short-chain dehydrogenase reductase Sdr
B6A42_26505	COG0384	phenazine biosynthesis protein PhzF
B6A42_26610	COG0583	DNA-binding transcription factor activity
B6A42_26730	COG1028	Short-chain dehydrogenase reductase Sdr
B6A42_26745	COG2274	protein secretion by the type I secretion system
B6A42_26895	COG0583	DNA-binding transcription factor activity
B6A42_26920	COG0625	glutathione transferase activity
B6A42_26925	COG0583	DNA-binding transcription factor activity
B6A42_27285	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B6A42_27290	COG2131	deaminase
B6A42_27385	COG1132	(ABC) transporter
B6A42_27390	COG1538	Outer membrane efflux protein
B6A42_27400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B6A42_27445	COG0753	catalase activity
B6A42_27565	COG2801	Transposase and inactivated derivatives
B6A42_27610	COG1192	Involved in chromosome partitioning